RPS-BLAST 2.2.16 [Mar-25-2007]

Database: Pfam-A 
           11,912 sequences; 2,039,872 total letters

Searching..................................................done

Query= CIRT_00357 cimm2 CIRG_00357 Broad_Institute ""
         (755 letters)



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PF07690 MFS_1 "Major Facilitator Superfamily"                          89   5e-21
PF06609 TRI12 "Fungal trichothecene efflux pump (TRI12)"               50   2e-09
PF00083 Sugar_tr "Sugar (and other) transporter"                       48   2e-08

>PF07690 MFS_1 "Major Facilitator Superfamily"
          Length = 347

 Score = 89.2 bits (221), Expect = 5e-21
 Identities = 55/176 (31%), Positives = 88/176 (50%), Gaps = 2/176 (1%)

Query: 164 LLSLGFYCMIGGGMTPILAAAFNDVSEEYNVSFQKVALTTGLYMLGLGIGSVVMSPTAIL 223
           LL LG++  + G    IL+ A   ++E+  +S  +V L    ++LG  +GS    P A  
Sbjct: 1   LLLLGYF--LSGLDRSILSPALPALAEDLGLSPSQVGLLLSAFLLGYALGSPPAGPLADR 58

Query: 224 FGKRPVYIAGATMFIISAVWCALSPTYVSLVIARIFQGIAVSPVECLPSATIAEIFFLHE 283
           FG+R V + G  +F + ++  A +     L++AR  QG+    +    SA IA+ F   E
Sbjct: 59  FGRRRVLLLGLLLFALGSLLLAFASNSWLLLVARFLQGLGAGGLFPAASALIADWFPPEE 118

Query: 284 RAYRVGIYTXXXXXXKNLIPLVSAAITEGLGWRWIFWVVAITIAFGLVLVFFFVPE 339
           R   +GI++        L PL+   + E LGWRW F ++AI     L+L    +PE
Sbjct: 119 RGRALGIFSAGGGLGAALGPLLGGLLAESLGWRWAFLILAILGLLALLLALLLLPE 174



 Score = 42.6 bits (100), Expect = 5e-07
 Identities = 34/124 (27%), Positives = 58/124 (46%), Gaps = 16/124 (12%)

Query: 569 KESYNFSALATGLVYISPFVGGILGTVVAGKVSDIIVRWMARRNGGIYEPEFRLVMSAPI 628
           +E   FSAL  GL+     + G +G+++ G++SD +             P  RL++   +
Sbjct: 234 QEVLGFSALQAGLLLALGGLVGAIGSLLGGRLSDRL------------GPRRRLLLGLLL 281

Query: 629 AICTAMGLMGFGWSAQEKEKWIVPTVFFGILSFGCTLGSTTSITFCVDSYRQYAGEALVT 688
            +  A+GL+  G ++     W++  V   +L FG  L     +    D   +YAG AL  
Sbjct: 282 LLLGALGLLLLGLTS--SPVWLL--VALALLGFGLGLAFPALLALLSDLVPEYAGTALGL 337

Query: 689 LNFS 692
           LNF+
Sbjct: 338 LNFA 341


>PF06609 TRI12 "Fungal trichothecene efflux pump (TRI12)"
          Length = 526

 Score = 50.5 bits (120), Expect = 2e-09
 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 1/137 (0%)

Query: 200 ALTTGLYMLGLGIGSVVMSPTAILFGKRPVYIAGATMFIISAVWCALSPTYVSLVIARIF 259
           +L + L+ LG  +  +V+   +  FG+RP  IAG  + ++ A+    + T+ +L+     
Sbjct: 38  SLFSTLWTLGQAVSILVVGRLSDRFGRRPFVIAGHILGLVGAIVGCTANTFNTLIAGMAL 97

Query: 260 QGIAVSPVECLPSATIAEIFFLHERAYRVGIYTXXXXXXKNLIPLVSAAITEGLGWRWIF 319
            G+   P E  P   I E+     +   + + +          P ++  ++    WRWIF
Sbjct: 98  LGVGAGPAELSP-LFIGELMSNKTKFLGLLVVSIPTIVATFAGPYLAQRLSIQGNWRWIF 156

Query: 320 WVVAITIAFGLVLVFFF 336
           ++  I  A  LVL+  F
Sbjct: 157 YIYIIWSAIALVLIVVF 173


>PF00083 Sugar_tr "Sugar (and other) transporter"
          Length = 433

 Score = 47.6 bits (113), Expect = 2e-08
 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 8/149 (5%)

Query: 199 VALTTGLYM----LGLGIGSVVMSPTAILFGKRPVYIAGATMFIISAVWCALSPTYVSLV 254
           V L TGL +    LG  IG++   P A  FG++   +    +  +  +  A +P    L+
Sbjct: 34  VGLLTGLVVSILFLGALIGALFFGPLADRFGRKKALLLSLLLMAVGTLLIAFAPNPALLI 93

Query: 255 IARIFQGIAVSPVECLPSATIAEIFFLHERAYRVGIYTXXXXXXKNLIPLVS---AAITE 311
           + R  QG+ V     +    I+EI    +R + V +Y         L  LV    + I  
Sbjct: 94  VGRFLQGLGVGGESGVAPVYISEIAPPKKRGFLVSLYQLFITLGILLAALVGYGLSLIGG 153

Query: 312 GLGWRWIFWVVAITIAFGLVLVFFFVPET 340
             GWR  F + A+  A  L+L   F+PE+
Sbjct: 154 DWGWRIPFGLGAVP-ALLLLLGRLFLPES 181



 Score = 42.6 bits (100), Expect = 5e-07
 Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 24/211 (11%)

Query: 144 QPEESLNDPLNWPQWRRDLAL-LSLGFYCMIGGGMTPILAAAFNDVSEEYNVSFQKVALT 202
           + E S  +    P +RR L L + L F+  + G          N ++      F+   L+
Sbjct: 223 EEEASWRELFRTPGYRRRLLLGVGLQFFQQLTG---------INAITYYAPTIFESAGLS 273

Query: 203 TG--LYMLGLGIGSVVMSPTAIL----FGKRPVYIAG-----ATMFIISAVWCALSPTYV 251
           +   L  + LG+ ++V +  AI     FG+RP+ + G      ++ I+         +  
Sbjct: 274 SSALLATIILGLVNLVGTLIAIFLVDRFGRRPLLLIGFLGMAISLLILGVALLGPDGSAG 333

Query: 252 SLVIARIFQGIAVSPVECLPSATI--AEIFFLHERAYRVGIYTXXXXXXKNLIPLVSAAI 309
            L IA IF  IA   +   P   +  AEIF    RA  VG+ T        ++P V   +
Sbjct: 334 ILAIAFIFLFIAFFAIGWGPVPWVYPAEIFPTRVRATGVGLATAVNWLGNFIVPFVFPYL 393

Query: 310 TEGLGWRWIFWVVAITIAFGLVLVFFFVPET 340
            E +G    F + A       + V+FF+PET
Sbjct: 394 LEAIG-GGTFLIFAGVCLLAALFVYFFLPET 423


  Database: Pfam-A
    Posted date:  Oct 30, 2009  9:48 AM
  Number of letters in database: 2,039,872
  Number of sequences in database:  11,912
  
Lambda     K      H
   0.326    0.140    0.437 

Gapped
Lambda     K      H
   0.267   0.0579    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11912
Number of Hits to DB: 21,375,430
Number of extensions: 1241923
Number of successful extensions: 158103
Number of sequences better than 1.0e-03: 10
Number of HSP's gapped: 2934
Number of HSP's successfully gapped: 206
Length of database: 100,000
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)