RPS-BLAST 2.2.16 [Mar-25-2007]

Database: 95pdb09Oct16_0000; 95pdb09Oct16_0001; 95pdb09Oct16_0002;
95pdb09Oct16_0003 
           66,450 sequences; 15,983,541 total letters

Searching..................................................done

Query= ACF68462.1 sent8 panE.2 GIB00763CH01 "2-dehydropantoate
2-reductase"
         (305 letters)



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

3egoB [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE                   99   2e-23
3egoA [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE                   94   4e-22
3dzbA [x.x.x] PREPHENATE DEHYDROGENASE                                 55   2e-10
3c7dB [x.x.x] OCTOPINE DEHYDROGENASE                                   55   3e-10
3c7aA [x.x.x] OCTOPINE DEHYDROGENASE                                   51   3e-09
3dzbB [x.x.x] PREPHENATE DEHYDROGENASE                                 49   2e-08
1bg6A [x.x.x] N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE          48   3e-08

>3egoB [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE
          Length = 291

 Score = 99.0 bits (245), Expect = 2e-23
 Identities = 58/303 (19%), Positives = 105/303 (34%), Gaps = 12/303 (3%)

Query: 1   MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAM 60
           +K        +G    Y  L   HDVT++   QE   AI+S+G+ +     +      A 
Sbjct: 1   LKIGIIGGGSVGLLCAY-YLSLYHDVTVVTRRQEQAAAIQSEGIRLYKGGEEFRADCSAD 59

Query: 61  LADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLGNIETLEKYVDRQKI 120
            +  S  +   +++  K  QL S+   ++ +     + +    G   I  L+ +     I
Sbjct: 60  TSINSDFDL--LVVTVKQHQLQSVFSSLERIGKTNILFLQNGMGH--IHDLKDWHVGHSI 115

Query: 121 YAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLL 180
           Y G+    +  +    +  TG G I+       +      ++   N +        D   
Sbjct: 116 YVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAE-PDRLNILFQHNHSDFPIYYETDWYR 174

Query: 181 SIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQMVM 240
            +  K   N+ +N   ALL    G     P  L   + V  E   +   +N     + V 
Sbjct: 175 LLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEACRILKLENEEKAWERVQ 234

Query: 241 NTVKKVFDPRESGHHYPSMHQDLHKGRLTEIDYLNGAIARIGAQNNIAVPVNKLLTQLIH 300
               +         +  SM  D+  GR TE D + G + +  +   +     + L   I 
Sbjct: 235 AVCGQTK------ENRSSMLVDVIGGRQTEADAIIGYLLKEASLQGLDAVHLEFLYGSIK 288

Query: 301 AKE 303
           A E
Sbjct: 289 ALE 291


>3egoA [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE
          Length = 292

 Score = 94.4 bits (233), Expect = 4e-22
 Identities = 57/303 (18%), Positives = 105/303 (34%), Gaps = 12/303 (3%)

Query: 1   MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAM 60
           +K        +G    Y  L   HDVT++   QE   AI+S+G+ +     +      A 
Sbjct: 2   LKIGIIGGGSVGLLCAY-YLSLYHDVTVVTRRQEQAAAIQSEGIRLYKGGEEFRADCSAD 60

Query: 61  LADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLGNIETLEKYVDRQKI 120
            +     +F+L+++  K  QL S+   ++ +     + +    G  +            I
Sbjct: 61  TSIN--SDFDLLVVTVKQHQLQSVFSSLERIGKTNILFLQNGMGHIHDLKDW--HVGHSI 116

Query: 121 YAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLL 180
           Y G+    +  +    +  TG G I+       +  +   ++   N +        D   
Sbjct: 117 YVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAEPDR-LNILFQHNHSDFPIYYETDWYR 175

Query: 181 SIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQMVM 240
            +  K   N+ +N   ALL    G     P  L   + V  E   +   +N     + V 
Sbjct: 176 LLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEACRILKLENEEKAWERVQ 235

Query: 241 NTVKKVFDPRESGHHYPSMHQDLHKGRLTEIDYLNGAIARIGAQNNIAVPVNKLLTQLIH 300
               +         +  SM  D+  GR TE D + G + +  +   +     + L   I 
Sbjct: 236 AVCGQTK------ENRSSMLVDVIGGRQTEADAIIGYLLKEASLQGLDAVHLEFLYGSIK 289

Query: 301 AKE 303
           A E
Sbjct: 290 ALE 292


>3dzbA [x.x.x] PREPHENATE DEHYDROGENASE
          Length = 281

 Score = 55.3 bits (132), Expect = 2e-10
 Identities = 14/268 (5%), Positives = 53/268 (19%), Gaps = 24/268 (8%)

Query: 19  LLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAMLADESQGEFELVILFTKA 78
                +++   +      +    +G+                 A  +    +++IL    
Sbjct: 21  RDHPDYEILGYNRSDYSRNIALERGIVDRATGD------FKEFAPLA----DVIILAVPI 70

Query: 79  MQLDSMLQRIKPLLPAAKVVMILSNGL-GNIETLEKYVDRQKIYAGVTLWSSELEGAGHI 137
            Q   + +     L    ++    +     +E  E+Y+  + +    +  +         
Sbjct: 71  KQTAYLKELADLDLKDNVIITDAGSTKREIVEAAERYLTGKNVQFVGSHPAGSAADVTLF 130

Query: 138 MATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCA 197
                      P +        ++   L+                      +        
Sbjct: 131 EN---AYYIFTPTSLTKETTIPELKDILSGLKSRYVEIDAAEHDRVTSQISHFPHLLASG 187

Query: 198 LLDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQMVMNTVKKVFDPRESGHHYP 257
           L       + Q       A     +  +  +                      +    + 
Sbjct: 188 L--EQAADYAQAHETNHFAAGGFRDTRIAESEPGWASILTN-------GPAVLDRIEDFK 238

Query: 258 S-MHQDLHKGRLTEIDYLNGAIARIGAQ 284
             +       +  +   +         +
Sbjct: 239 KRLDHVADLIKAEDESAIWEFFDNGRKK 266


>3c7dB [x.x.x] OCTOPINE DEHYDROGENASE
          Length = 393

 Score = 54.9 bits (130), Expect = 3e-10
 Identities = 26/354 (7%), Positives = 75/354 (21%), Gaps = 53/354 (14%)

Query: 1   MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEH------------VDAIRSKGLFVET 48
           +K               +          +                     +         
Sbjct: 2   VKVCVCGGGNGAHTLSGLAASRDGVEVRVLTLFADEAERWTKALGADELTVIVNEKDGTQ 61

Query: 49  ETTQKYYPIPAMLADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLG-N 107
              +    +     + +    ++VIL   A   +   Q + P +  + +++ L +  G  
Sbjct: 62  TEVKSRPKVITKDPEIAISGADVVILTVPAFAHEGYFQAMAPYVQDSALIVGLPSQAGFE 121

Query: 108 IETLEKYVDRQKIYAGVTLWSSELEGAGHIMATGTGTIELQP-------IASQDSAQEAK 160
            +  +   D+    + ++  +                +  +          +  +     
Sbjct: 122 FQCRDILGDKAAAVSMMSFETLPWACRIKEFGRKVEVLGTKSVLAASLIKGTAKTVDPLS 181

Query: 161 VIATLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCALLDCNVGGFGQ--------RPGA 212
            +  L+ A     ++   L  +    +F      +      +     +            
Sbjct: 182 TLQMLHGAEPVFRLAKHFLEMLIMSYSFVHPAILFGRWGSWDGKPVPEAPLFYQGIDQAT 241

Query: 213 LDLAQAVVDEFVLVAASQNIPLTEQMVMNTVKKVFDPRESGHHYPSMHQDLHKGR----- 267
            D+  A  +E   VA +         + +        +   H            +     
Sbjct: 242 ADMLTACSNECKDVANAIMAACPGNDLSDVKDIY---QWYLHDLYHAITTNKSYKGLVHP 298

Query: 268 -----------------LTEIDYLNGAIARIGAQNNIAVPVNKLLTQLIHAKEA 304
                              +I         +     +A+P N  L      K  
Sbjct: 299 VKAVDGGVAPDFGNRYLTEDIPMGMIVFKGVAIAAGVAIPSNDKLIMWAQEKIG 352


>3c7aA [x.x.x] OCTOPINE DEHYDROGENASE
          Length = 403

 Score = 51.5 bits (121), Expect = 3e-09
 Identities = 30/324 (9%), Positives = 73/324 (22%), Gaps = 23/324 (7%)

Query: 1   MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEH------------VDAIRSKGLFVET 48
           +K               +          +                     +         
Sbjct: 2   VKVCVCGGGNGAHTLSGLAASRDGVEVRVLTLFADEAERWTKALGADELTVIVNEKDGTQ 61

Query: 49  ETTQKYYPIPAMLADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLG-- 106
              +    +     + +    ++VIL   A   +   Q + P +  + +++ L +  G  
Sbjct: 62  TEVKSRPKVITKDPEIAISGADVVILTVPAFAHEGYFQAMAPYVQDSALIVGLPSQAGFE 121

Query: 107 ---NIETLEKYVDRQKIYAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIA 163
                   +K      +      W+  ++  G  +            AS        V  
Sbjct: 122 FQCRDILGDKAAAVSMMSFETLPWACRIKEFGRKVEVLGTKSV--LAASLIKGTAKTVDP 179

Query: 164 TLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVDEF 223
                 L+       L   + +    S    + A+L    G +  +P           + 
Sbjct: 180 LSTLQMLHGAEPVFRLAKHFLEMLIMSYSFVHPAILFGRWGSWDGKPVPEAPLFYQGIDQ 239

Query: 224 VLVAASQNIPLTEQMVMNTVKKVFDPRESGH---HYPSMHQDLHKGRLTEIDYLNGAIAR 280
                        + V N +     P             + + +   + +   L  AI  
Sbjct: 240 ATADMLTACSNECKDVANAIMAA-CPGNDLSDVKDIYQWYLEYYHEDIQDDHDLYHAITT 298

Query: 281 IGAQNNIAVPVNKLLTQLIHAKEA 304
             +   +  PV  +   +      
Sbjct: 299 NKSYKGLVHPVKAVDGGVAPDFGN 322


>3dzbB [x.x.x] PREPHENATE DEHYDROGENASE
          Length = 270

 Score = 49.2 bits (116), Expect = 2e-08
 Identities = 12/220 (5%), Positives = 37/220 (16%), Gaps = 13/220 (5%)

Query: 19  LLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAMLADESQGEFELVILFTKA 78
                +++   +      +    +G+                   E     +++IL    
Sbjct: 21  RDHPDYEILGYNRSDYSRNIALERGIVDRATGD----------FKEFAPLADVIILAVPI 70

Query: 79  MQLDSMLQRIKPLLPAAKVVMILSNGLGNIETLEKYVDRQKIYAGVTLWSSELEGAGHIM 138
            Q   + +     L    ++    +                              A  + 
Sbjct: 71  KQTAYLKELADLDLKDNVIITDAGST-KREIVEAAERYLTGKNVQFVGSHPAGSHAADVT 129

Query: 139 ATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCAL 198
                     P +        ++   L+                      +        L
Sbjct: 130 LFENAYYIFTPTSLTKETTIPELKDILSGLKSRYVEIDAAEHDRVTSQISHFPHLLASGL 189

Query: 199 LDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQM 238
                  + Q       A     +  +  +          
Sbjct: 190 --EQAADYAQAHETNHFAAGGFRDTRIAESEPGWASILTN 227


>1bg6A [x.x.x] N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE
          Length = 349

 Score = 48.2 bits (113), Expect = 3e-08
 Identities = 28/311 (9%), Positives = 82/311 (26%), Gaps = 16/311 (5%)

Query: 11  MGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQK---YYPIPAMLADESQG 67
            G  F   L   G  V   D   + +  I+ +G  +          +  +       +  
Sbjct: 12  GGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPDLLTSDIGLAVK 71

Query: 68  EFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLG---NIETLEKYVDRQKI-YAG 123
           + +++++   A+   S+   I   +   +++++     G       + +     ++    
Sbjct: 72  DADVILIVVPAIHHASIAANIASYISEGQLIILNPGATGGALEFRKILRENGAPEVTIGE 131

Query: 124 VTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLLSIW 183
            +              T          A   +A+    +  + S         +VL +  
Sbjct: 132 TSSMLFTCRSERPGQVTVNAIKGAMDFACLPAAKAGWALEQIGSVLPQYVAVENVLHTSL 191

Query: 184 KKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVD-------EFVLVAASQNIPLTE 236
                                G   +     +  +V         E + +A + ++ +  
Sbjct: 192 TNVNAVMHPLPTLLNAARCESGTPFQYYLEGITPSVGSLAEKVDAERIAIAKAFDLNVPS 251

Query: 237 QMVMNTVKKVFDPRESGHHYPSMHQDLHKGR--LTEIDYLNGAIARIGAQNNIAVPVNKL 294
                        + +  +           R    ++      ++ +G   N+  P+   
Sbjct: 252 VCEWYPATIYEAVQGNPAYRGIAGPINLNTRYFFEDVSTGLVPLSELGRAVNVPTPLIDA 311

Query: 295 LTQLIHAKEAQ 305
           +  LI +    
Sbjct: 312 VLDLISSLIDT 322


  Database: 95pdb09Oct16_0000
    Posted date:  Oct 27, 2009  4:27 PM
  Number of letters in database: 15,983,541
  Number of sequences in database:  66,450
  
Lambda     K      H
   0.324    0.138    0.428 

Gapped
Lambda     K      H
   0.267   0.0485    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 66450
Number of Hits to DB: 20,669,662
Number of extensions: 1238167
Number of successful extensions: 14106
Number of sequences better than 1.0e-03: 10
Number of HSP's gapped: 6002
Number of HSP's successfully gapped: 268
Length of database: 100,000
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)