RPS-BLAST 2.2.16 [Mar-25-2007]
Database: 95pdb09Oct16_0000; 95pdb09Oct16_0001; 95pdb09Oct16_0002;
95pdb09Oct16_0003
66,450 sequences; 15,983,541 total letters
Searching..................................................done
Query= ACF68462.1 sent8 panE.2 GIB00763CH01 "2-dehydropantoate
2-reductase"
(305 letters)
Score E
Sequences producing significant alignments: (bits) Value
3egoB [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE 99 2e-23
3egoA [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE 94 4e-22
3dzbA [x.x.x] PREPHENATE DEHYDROGENASE 55 2e-10
3c7dB [x.x.x] OCTOPINE DEHYDROGENASE 55 3e-10
3c7aA [x.x.x] OCTOPINE DEHYDROGENASE 51 3e-09
3dzbB [x.x.x] PREPHENATE DEHYDROGENASE 49 2e-08
1bg6A [x.x.x] N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE 48 3e-08
>3egoB [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE
Length = 291
Score = 99.0 bits (245), Expect = 2e-23
Identities = 58/303 (19%), Positives = 105/303 (34%), Gaps = 12/303 (3%)
Query: 1 MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAM 60
+K +G Y L HDVT++ QE AI+S+G+ + + A
Sbjct: 1 LKIGIIGGGSVGLLCAY-YLSLYHDVTVVTRRQEQAAAIQSEGIRLYKGGEEFRADCSAD 59
Query: 61 LADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLGNIETLEKYVDRQKI 120
+ S + +++ K QL S+ ++ + + + G I L+ + I
Sbjct: 60 TSINSDFDL--LVVTVKQHQLQSVFSSLERIGKTNILFLQNGMGH--IHDLKDWHVGHSI 115
Query: 121 YAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLL 180
Y G+ + + + TG G I+ + ++ N + D
Sbjct: 116 YVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAE-PDRLNILFQHNHSDFPIYYETDWYR 174
Query: 181 SIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQMVM 240
+ K N+ +N ALL G P L + V E + +N + V
Sbjct: 175 LLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEACRILKLENEEKAWERVQ 234
Query: 241 NTVKKVFDPRESGHHYPSMHQDLHKGRLTEIDYLNGAIARIGAQNNIAVPVNKLLTQLIH 300
+ + SM D+ GR TE D + G + + + + + L I
Sbjct: 235 AVCGQTK------ENRSSMLVDVIGGRQTEADAIIGYLLKEASLQGLDAVHLEFLYGSIK 288
Query: 301 AKE 303
A E
Sbjct: 289 ALE 291
>3egoA [x.x.x] PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE
Length = 292
Score = 94.4 bits (233), Expect = 4e-22
Identities = 57/303 (18%), Positives = 105/303 (34%), Gaps = 12/303 (3%)
Query: 1 MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAM 60
+K +G Y L HDVT++ QE AI+S+G+ + + A
Sbjct: 2 LKIGIIGGGSVGLLCAY-YLSLYHDVTVVTRRQEQAAAIQSEGIRLYKGGEEFRADCSAD 60
Query: 61 LADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLGNIETLEKYVDRQKI 120
+ +F+L+++ K QL S+ ++ + + + G + I
Sbjct: 61 TSIN--SDFDLLVVTVKQHQLQSVFSSLERIGKTNILFLQNGMGHIHDLKDW--HVGHSI 116
Query: 121 YAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLL 180
Y G+ + + + TG G I+ + + ++ N + D
Sbjct: 117 YVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAEPDR-LNILFQHNHSDFPIYYETDWYR 175
Query: 181 SIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQMVM 240
+ K N+ +N ALL G P L + V E + +N + V
Sbjct: 176 LLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEACRILKLENEEKAWERVQ 235
Query: 241 NTVKKVFDPRESGHHYPSMHQDLHKGRLTEIDYLNGAIARIGAQNNIAVPVNKLLTQLIH 300
+ + SM D+ GR TE D + G + + + + + L I
Sbjct: 236 AVCGQTK------ENRSSMLVDVIGGRQTEADAIIGYLLKEASLQGLDAVHLEFLYGSIK 289
Query: 301 AKE 303
A E
Sbjct: 290 ALE 292
>3dzbA [x.x.x] PREPHENATE DEHYDROGENASE
Length = 281
Score = 55.3 bits (132), Expect = 2e-10
Identities = 14/268 (5%), Positives = 53/268 (19%), Gaps = 24/268 (8%)
Query: 19 LLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAMLADESQGEFELVILFTKA 78
+++ + + +G+ A + +++IL
Sbjct: 21 RDHPDYEILGYNRSDYSRNIALERGIVDRATGD------FKEFAPLA----DVIILAVPI 70
Query: 79 MQLDSMLQRIKPLLPAAKVVMILSNGL-GNIETLEKYVDRQKIYAGVTLWSSELEGAGHI 137
Q + + L ++ + +E E+Y+ + + + +
Sbjct: 71 KQTAYLKELADLDLKDNVIITDAGSTKREIVEAAERYLTGKNVQFVGSHPAGSAADVTLF 130
Query: 138 MATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCA 197
P + ++ L+ +
Sbjct: 131 EN---AYYIFTPTSLTKETTIPELKDILSGLKSRYVEIDAAEHDRVTSQISHFPHLLASG 187
Query: 198 LLDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQMVMNTVKKVFDPRESGHHYP 257
L + Q A + + + + +
Sbjct: 188 L--EQAADYAQAHETNHFAAGGFRDTRIAESEPGWASILTN-------GPAVLDRIEDFK 238
Query: 258 S-MHQDLHKGRLTEIDYLNGAIARIGAQ 284
+ + + + +
Sbjct: 239 KRLDHVADLIKAEDESAIWEFFDNGRKK 266
>3c7dB [x.x.x] OCTOPINE DEHYDROGENASE
Length = 393
Score = 54.9 bits (130), Expect = 3e-10
Identities = 26/354 (7%), Positives = 75/354 (21%), Gaps = 53/354 (14%)
Query: 1 MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEH------------VDAIRSKGLFVET 48
+K + + +
Sbjct: 2 VKVCVCGGGNGAHTLSGLAASRDGVEVRVLTLFADEAERWTKALGADELTVIVNEKDGTQ 61
Query: 49 ETTQKYYPIPAMLADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLG-N 107
+ + + + ++VIL A + Q + P + + +++ L + G
Sbjct: 62 TEVKSRPKVITKDPEIAISGADVVILTVPAFAHEGYFQAMAPYVQDSALIVGLPSQAGFE 121
Query: 108 IETLEKYVDRQKIYAGVTLWSSELEGAGHIMATGTGTIELQP-------IASQDSAQEAK 160
+ + D+ + ++ + + + + +
Sbjct: 122 FQCRDILGDKAAAVSMMSFETLPWACRIKEFGRKVEVLGTKSVLAASLIKGTAKTVDPLS 181
Query: 161 VIATLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCALLDCNVGGFGQ--------RPGA 212
+ L+ A ++ L + +F + + +
Sbjct: 182 TLQMLHGAEPVFRLAKHFLEMLIMSYSFVHPAILFGRWGSWDGKPVPEAPLFYQGIDQAT 241
Query: 213 LDLAQAVVDEFVLVAASQNIPLTEQMVMNTVKKVFDPRESGHHYPSMHQDLHKGR----- 267
D+ A +E VA + + + + H +
Sbjct: 242 ADMLTACSNECKDVANAIMAACPGNDLSDVKDIY---QWYLHDLYHAITTNKSYKGLVHP 298
Query: 268 -----------------LTEIDYLNGAIARIGAQNNIAVPVNKLLTQLIHAKEA 304
+I + +A+P N L K
Sbjct: 299 VKAVDGGVAPDFGNRYLTEDIPMGMIVFKGVAIAAGVAIPSNDKLIMWAQEKIG 352
>3c7aA [x.x.x] OCTOPINE DEHYDROGENASE
Length = 403
Score = 51.5 bits (121), Expect = 3e-09
Identities = 30/324 (9%), Positives = 73/324 (22%), Gaps = 23/324 (7%)
Query: 1 MKXXXXXXXXMGCRFGYMLLEAGHDVTLIDGWQEH------------VDAIRSKGLFVET 48
+K + + +
Sbjct: 2 VKVCVCGGGNGAHTLSGLAASRDGVEVRVLTLFADEAERWTKALGADELTVIVNEKDGTQ 61
Query: 49 ETTQKYYPIPAMLADESQGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLG-- 106
+ + + + ++VIL A + Q + P + + +++ L + G
Sbjct: 62 TEVKSRPKVITKDPEIAISGADVVILTVPAFAHEGYFQAMAPYVQDSALIVGLPSQAGFE 121
Query: 107 ---NIETLEKYVDRQKIYAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIA 163
+K + W+ ++ G + AS V
Sbjct: 122 FQCRDILGDKAAAVSMMSFETLPWACRIKEFGRKVEVLGTKSV--LAASLIKGTAKTVDP 179
Query: 164 TLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVDEF 223
L+ L + + S + A+L G + +P +
Sbjct: 180 LSTLQMLHGAEPVFRLAKHFLEMLIMSYSFVHPAILFGRWGSWDGKPVPEAPLFYQGIDQ 239
Query: 224 VLVAASQNIPLTEQMVMNTVKKVFDPRESGH---HYPSMHQDLHKGRLTEIDYLNGAIAR 280
+ V N + P + + + + + L AI
Sbjct: 240 ATADMLTACSNECKDVANAIMAA-CPGNDLSDVKDIYQWYLEYYHEDIQDDHDLYHAITT 298
Query: 281 IGAQNNIAVPVNKLLTQLIHAKEA 304
+ + PV + +
Sbjct: 299 NKSYKGLVHPVKAVDGGVAPDFGN 322
>3dzbB [x.x.x] PREPHENATE DEHYDROGENASE
Length = 270
Score = 49.2 bits (116), Expect = 2e-08
Identities = 12/220 (5%), Positives = 37/220 (16%), Gaps = 13/220 (5%)
Query: 19 LLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQKYYPIPAMLADESQGEFELVILFTKA 78
+++ + + +G+ E +++IL
Sbjct: 21 RDHPDYEILGYNRSDYSRNIALERGIVDRATGD----------FKEFAPLADVIILAVPI 70
Query: 79 MQLDSMLQRIKPLLPAAKVVMILSNGLGNIETLEKYVDRQKIYAGVTLWSSELEGAGHIM 138
Q + + L ++ + A +
Sbjct: 71 KQTAYLKELADLDLKDNVIITDAGST-KREIVEAAERYLTGKNVQFVGSHPAGSHAADVT 129
Query: 139 ATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLLSIWKKAAFNSVMNTYCAL 198
P + ++ L+ + L
Sbjct: 130 LFENAYYIFTPTSLTKETTIPELKDILSGLKSRYVEIDAAEHDRVTSQISHFPHLLASGL 189
Query: 199 LDCNVGGFGQRPGALDLAQAVVDEFVLVAASQNIPLTEQM 238
+ Q A + + +
Sbjct: 190 --EQAADYAQAHETNHFAAGGFRDTRIAESEPGWASILTN 227
>1bg6A [x.x.x] N-(1-D-CARBOXYLETHYL)-L-NORVALINE DEHYDROGENASE
Length = 349
Score = 48.2 bits (113), Expect = 3e-08
Identities = 28/311 (9%), Positives = 82/311 (26%), Gaps = 16/311 (5%)
Query: 11 MGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGLFVETETTQK---YYPIPAMLADESQG 67
G F L G V D + + I+ +G + + + +
Sbjct: 12 GGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPDLLTSDIGLAVK 71
Query: 68 EFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLG---NIETLEKYVDRQKI-YAG 123
+ +++++ A+ S+ I + +++++ G + + ++
Sbjct: 72 DADVILIVVPAIHHASIAANIASYISEGQLIILNPGATGGALEFRKILRENGAPEVTIGE 131
Query: 124 VTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIATLNSAGLNAEISPDVLLSIW 183
+ T A +A+ + + S +VL +
Sbjct: 132 TSSMLFTCRSERPGQVTVNAIKGAMDFACLPAAKAGWALEQIGSVLPQYVAVENVLHTSL 191
Query: 184 KKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVD-------EFVLVAASQNIPLTE 236
G + + +V E + +A + ++ +
Sbjct: 192 TNVNAVMHPLPTLLNAARCESGTPFQYYLEGITPSVGSLAEKVDAERIAIAKAFDLNVPS 251
Query: 237 QMVMNTVKKVFDPRESGHHYPSMHQDLHKGR--LTEIDYLNGAIARIGAQNNIAVPVNKL 294
+ + + R ++ ++ +G N+ P+
Sbjct: 252 VCEWYPATIYEAVQGNPAYRGIAGPINLNTRYFFEDVSTGLVPLSELGRAVNVPTPLIDA 311
Query: 295 LTQLIHAKEAQ 305
+ LI +
Sbjct: 312 VLDLISSLIDT 322
Database: 95pdb09Oct16_0000
Posted date: Oct 27, 2009 4:27 PM
Number of letters in database: 15,983,541
Number of sequences in database: 66,450
Lambda K H
0.324 0.138 0.428
Gapped
Lambda K H
0.267 0.0485 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 66450
Number of Hits to DB: 20,669,662
Number of extensions: 1238167
Number of successful extensions: 14106
Number of sequences better than 1.0e-03: 10
Number of HSP's gapped: 6002
Number of HSP's successfully gapped: 268
Length of database: 100,000
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)