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Ranking of HM:PFM:REP : from 7601 to 7700

                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7601] PF07892            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1667:Protein of unknown fu  --1-1--1--------------------111-------------1---------11-2111------- ------------------------------------1--------------------------11---------------11--------------1--------1----111111-------1---------------------------------------------------------------11---------------------11--------1-----------------1-21---12---------------------------------------1-1--1-------1111111111111----------111222222224222--11223222-1---1--------1---111211-----------1--------------------------------------------1------------1---------------------------------------------------------------------------------------------------4--------1-----------------------------------------1--------1-------------------------------------1---------1-----------------------------------------------------------------------------------------------1-11-1--1---------------------------------------------------------------------------------------------------------2--------------2---------------111---------1111112111---- ----1---1-11-12---1-1-1111------1-------------11----------------------------1------------------1-------------7---1--1-------12---1------11--------------------------1----------------1------1-1--------
 nction (DUF1667)                 * *  *                    ***             *         ** ****                                            *                          **               **              *        *    ******       *                                                               **                     **        *                 * **   **                                       * *  *       *************          ***************  ******** *   *        *   ******           *                                            *            *                                                                                                   *        *                                         *        *                                     *         *                                                                                               * ** *  *                                                                                                         *              *               ***         **********         *   * ** **   * * ****      *             **                            *                  *             *   *  *       **   *      **                          *                *      * *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7602] PF10050            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2284:Predicted metal-bindi  ---1-------------------1--------11---------2311-1-321-1111111------- ------1-----1---------------------------------------------------------------------------1-11----------------------------------------1------------1-----------------------------------------------------1----------------------------------------------------1----------------------------------------------------------------------1--------1--1----------1--------11-11--12----------2---------------------------------------1-------------------------11-11----------------------------------------------------------------------------1-------------------------------------------------321--12------------1-13------11--------------------1---1--------------------1--------------1------------------------------------------------------------------------------------------------11111----1---------------------1-1-1--------------------------------1-------------------1------------------------------------------------------------------- -11111--1---11--13--11------------1-11-2--7------1--2-21132-11-----------1----1-------1-----1---------------1231-1-1-1---1--11-21----2121---1-1---------11-1--1---11111-121142---1---1---11-2-----11---
 ng protein (DUF2284)              *                   *        **         **** * *** *******              *     *                                                                           * **                                        *            *                                                     *                                                    *                                                                      *        *  *          *        ** **  **          *                                       *                         ** **                                                                            *                                                 ***  **            * **      **                    *   *                    *              *                                                                                                *****    *                     * * *                                *                   *                                                                     *****  *   **  **  **            * ** *  *      *  * ***** **           *    *       *     *               **** * * *   *  ** **    ****   * *         ** *  *   ***** ******   *   *   ** *     **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7603] PF10479            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 FSA_C:Fragile site-associated  ----1--------------------------------------------------------------- ------------------------------------------------------------------------------------------------------1---------------------------------------------------11-------------2-----------------------11111-----------1----------1---------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------1----1-----11-----------------------------------------------------1-----------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------11111111----------------------111---------------------------------------------------------------- --1-1---------1------1----------------1--------------------1-1----------------------------1----1--1----1--12--21131131213411211135-1121211233-32211112121221115335221361216-131-----2----2--1-2-----14-
  protein C-terminus                *                                                                                                                                                                      *                                                   **             *                       *****           *          *                                                                                             *                                                                                                              *                                                                                                                                                *    *     **                                                     *                                                                             *                                                                                                       ********                      ***                                                                   * *         *      *                *                    * *                            *    *  *    *  **  ******************** ********** ***************************** ***     *    *  * *     ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7604] PF09432            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 THP2:Tho complex subunit THP2  ----1---------1------------------1--------11--------1--------------- -----------------------------------------------------------------------------------1---111----------1-------1-------------------------------------1---1-------------------------------------1-------------1----------1------1---------1-------------------1------------------------------------------------111111--1--1----111-----1---------1-1--132-----------1-------11------------------------------------------------------------11-----------------------1------------------------------11--------------------------------------------------------------------------------------------1------------------------------1---------2-11121112-------------------------1----1-1---------------------11---1----------------------------------------------------------------------------------111------------------------------------------------------1-----------------------------------------------------------1-----------1---------1---------- 11---21------2---2------------------------1--1------2----------111111-11---121211-----1------1--211--6-114---1-33212-1---------1-------4---11---1--1111-1-1313-24--12-22-1-1----11--1-----12---11------
                                    *         *                  *        **        *                                                                                                   *   ***          *       *                                     *   *                                     *             *          *      *         *                   *                                                ******  *  *    ***     *         * *  ***           *       **                                                            **                       *                              **                                                                                            *                              *         * ********                         *    * *                     **   *                                                                                  ***                                                      *                                                           *           *         *           **   **      *   *                        *  *      *          ****** **   ******     *      *  ***  * ***   * ***** *         *       *   **   *  **** * **** **  ** ** * *    **  *     **   **      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7605] PF10782            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2602:Protein of unknown fu  -------1------------------------------1111-------------------------- ------1----------------------------------------------22----------------------------------------------------------------------------------------------------------1---------1---------------11---123-332233322123--1111--41111------------11-11111-111-1-1111------------------------------------11----111-1-------------------------1-----------------121--------1-------1-----------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------1----------------------------1-----1------ -2--112-1------1-------------2-----------111--1------2-----------------1---1------------------1--------------1-11---21111----11114-1-1112112111--11--23211---1--2-12-4--111-12-1---------3-211-3----1--
 nction (DUF2602)                      *                              ****                                 *                                              **                                                                                                          *         *               **   *** ************  ****  *****            ** ***** *** * ****                                    **    *** *                         *                 ***        *       *                                                                                                                                                           *                                                                                                                                                                                                                                                                                         *                                                                         *                            *     *        *  *** *      *             *           ***  *      *                 *   *                  *              * **   *****    ***** * **********  **  *****   *  * ** *  *** ** *         * *** *    *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7606] PF09696            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Ctf8:Ctf8                      ---------1---1------------------------------------------------------ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------1------------------------------------------------------------------------1------------------------------------------1------------------------------------1--------------1-------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------1--------1------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------ --1212--1111112111112111111111-11111111111121111111111-1111111111112222111211111111111111-1111121222-22111-124212--11--------1---4-3--1---------------1----1-11---111-1113--112-11-----111--21111-1-11-
                                         *   *                                                                                                                                                                                                                                 *          *                                                                        *                                          *                                    *              *             *                                                                                                                                                                                           *                                                                         *        *                                          *                                                                                                                                                                                                                                *               ****  ********************** *********************** ********************************** ********** ***** ******  **        *   * *  *               *    * **   *** ****  *** **     ***  ***** * ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7607] PF03818            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 MadM:Malonate/sodium symporte  ----------1-------------------------11------1------------------1-1-1 ----------1----------1---------------1-----------1-------1--11-----11----------------------------------1-------------------------------1-----------11------------1------1-------------------------------------1-1--------------1-------1---------------2-------------------------------------------------------------------111-------------------11------1-1--------------1------------1---------311-----1-1----2--1-------1--11--------1----1-------1---1111-11---------------1----------1-----------------1--11---111-11111111111111111122121-11----11-------1--1-------1-------------1-----------------1-----------11------------1------------------1---------------------1------------------------------------------------------1-----------------------------------------------------------11----------------1-22112-11--1-1111-111--1-11122-----------1--------1-------------1-------------1---------------------------------------1--------- --1------------1----1211-------------------------1-2-1--1-------------1-------11---------------1---------1--2---1-----------22-----1---1---1--1------1----------1-1--11-----1------------122----------1
 r MadM subunit                           *                         **      *                  * * *           *          *               *           *       *  **     **                                  *                               *           **            *      *                                     * *              *       *               *                                                                   ***                   **      * *              *            *         ***     * *    *  *       *  **        *    *       *   **** **               *          *                 *  **   *** *********************** **    **       *  *       *             *                 *           **            *                  *                     *                                                      *                                                           **                * ***** **  * **** ***  * *****           *        *             *             *                                       *            *            *    ****                         * * *  *             *       **               *         *  *   *           **     *   *   *  *      *          * *  **     *            ***          *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7608] PF10451            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Stn1:Telomere regulation prot  -----------1-----------1------------1------------------------------- -------------------------------------------------------------------------------1----------------------1-1--1---------------------------------1---1------------1--------------1-----1--------------------------------------------1------1-----------------------------------------------------1------------------------------------------------1-2------------1------------------------1------------------------------------------------------------------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------------11--------------1-------1----1-----------------------------------------------------------------------------1-111-----------------------------------------------------------------------------------------1--------------------------------------------------------1--------------------------------111-1---- --------1-1----11121222-1-1112212111222222222211112211231111111111111-1111-111412---1--1---2111--11--1--11---1---2---1--1--1-----4-2-4-2------------1-----11-----1111-1--12-----2-----1--111122---11-1-
 ein Stn1                                  *           *            *                                                                                                               *                      * *  *                                 *   *            *              *     *                                            *      *                                                     *                                                * *            *                        *                                                                                                                  **                                                                                                                            **              *       *    *                                                                             * ***                                                                                         *                                                        *                                *** *             * *    ******** * ******************************************* **** ******   *  *   ****  **  *  **   *   *   *  *  *     * * * *            *     **     **** *  **     *     *  ******   ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7609] PF11074            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2779:Domain of unknown fun  ------------11--------------------------------------2--------------- --1------------------------------------------1-------1----------------------------------------------1-2--------------------------2----1-----1-1---1112221111------12-----1------1----1-------1--------------1-------------------1--------111-1------1-1--------1--2---------------1------1111------------------------------------------1111123111--------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------11------------------1-------2-11---------1---1---1-1--------1-----------1-11--1----2-1---1-------------------------------1--------------1-------11----1----------1------------------------------------------------------------1--1---1-----------------1------------------------------------------------------------------2-111111----------1111-1-11111111111111221111-1----------- 121111-1311------1----1-------------------------1-----------1-----------------1------1------------------21----2--11-----------1--1-----1-------------1-1-----2----1121-1------2-1-----------11---1121-1
 ction(DUF2779)                             **                                      *                  *                                          *       *                                              * *                          *    *     * *   **********      **     *      *    *       *              *                   *        *** *      * *        *  *               *      ****                                          **********                                                                                                                                                              *                                               **                  *       * **         *   *   * *        *           * **  *    * *   *                               *              *       **    *          *                                                            *  *   *                 *                                                                  * ******          **** * ******************** *            ****** ****      *    *                         *           *                 *      *                  **    *  **           *  *     *             * *     *    **** *      * *           **   **** *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7610] PF10126            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
 Nit_Regul_Hom:Uncharacterized  -------------1---1----------------1221111121----1-1111------1------- -1---1-----------------------------------------------------------------------1----------------------1-----1------------------------------------1------11-----------------------------------------11111---1111-11--------1--------1111----11111111111111--------1----------------------1--------------------------------------------1-1--------------------1--1-------------------1----------------1-----------------------1----------------------------------1----------------------1------3------------1-------1-------1--------------------------------1------------1------11-------1-----1------------1--------------------------------------1-1------------2----------------------------------------------------------------------------------2-111-------------------------------1------1----1------------------------11--------------1---------------------------------------------------------1---1--------------------------------1-111---- 2-12-------1--1-----1------11--11------------------1-1---------11--1---------------------------1--------------1----2---1112111-112-1-211112--111--111-1--11----------1----1-313----2-----2-----1-1-1---
  protein, homolog of nitrogen               *   *                **********    * ****      *         *   *                                                                       *                      *     *                                    *      **                                         *****   **** **        *        ****    **************        *                      *                                            * *                    *  *                   *                *                       *                                  *                      *      *            *       *       *                                *            *      **       *     *            *                                      * *            *                                                                                  * ***                               *      *    *                        **              *                                                         *   *                                * ***     * **       *  *     *      **  **                  * *         **  *                           *              *    *   ******* *** * ******  ***  *** *  **          *    * ***    *     *     * * *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 0002000001200001001230016001234000120000000100000010000000010000000000000120010100000C0101000001001000000000000123450000123020000100000011000100010123400101123456700010000123456789AB1000100001001234012345678900010001020100000012300000123456789ABCD001000000010000001010100000001201210120010123456789A0123456789ABC00101201200000001234567890001001200000000000100000001010000000000101000000001000012340100120001000000100000000010010012000000500001230010123456700100000020000120001000100000001001000000000000000123000123010101234000000100001000000000010000101100010123400001000000000200012200100000001010010000010123400001234562000001000000000000012300001230000000000000001234000000000123456789ABCDEFGHIJKLMNOPQRS0012010000123456789A0123400100120000012345678010000012340123000000120000012300100123450000000234001200123001200123456701011012340000101001230120123000001010100100000000010001001010001200000000100000100000000 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7611] PF01241            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               1                   
 PSI_PSAK:Photosystem I psaG /  -------------1------------------------------------------------------ ----1--------------------------------------1-------1---------------1----------------------------------1-2--------------1111----------------------2224222112211121222113332121111121111-------------------1----1----------------------------------------------------------------------------------------------------------11-----------------------------------------------1--------------------1-----------1-------------------------2---22122---1----------------------------------------------1---------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1-------------------1-1------------1----1-------------------------------------------------------------------------------------------1-----------1----------------------------------------------------------------------1--------------------111-------------- ----1--------------2--------------------------------1----11----1--------------------------1---3---------------4--------1-1---1-------------------------------------2-11----21--12221222226236-52-------
  psaK                                       *                                                           *                                      *       *               *                                  * *              ****                      *************************************                   *    *                                                                                                          **                                               *                    *           *                         *   *****   *                                              *                                             *                                                                                                                                       *                   * *            *    *                                                                                           *           *                                                                      *                    ***                   *              *                                *    **    *                          *   *               *        * *   *                                     * **    **  ************** **       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7612] PF03615            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 GCM:GCM motif protein          --------------1---------1------------------------------------------- ----------------------11-----------------1-------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------1----1-----------------------------------------------------------------------------------1------------1--------------------------------------------------1-------------------------------111--------------------------1----------------------------------------1---------------------------------------------1----------------1-------11------------------------------------------------------------------------2--------------1--------------------------1-----------------------------------------------------1----------------------------1----2----------------------------------1-----------------1----------------------------------------------------------- -----1----------1-------------1------------1---------1--2--21--1---------------2---------1--11-1-----6-1----1-41132222222222222212-2-22422223222122221222213322---521123231--21-11-------4--1-----1----
                                              *         *                                                                  **                 *                                                                                                             *                                                                                                                        *    *                                                                                   *            *                                                  *                               ***                          *                                        *                                             *                *       **                                                                        *              *                          *                                                     *                            *    *                                  *                 *                                                                 *          *             *            *         *  *  **  *               *         *  ** *     * *    * ******************** * **************************   *********  ** **       *  *     *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7613] PF02387            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 IncFII_repA:IncFII RepA prote  --------------1---------------------------1------------------------- 1--------------------------------------------------1-----1----------------------------1-------11---------1-------------------------------1--------1----------------------1--------1------------------------1-----1-----1-----------------------1-------1---------------------1--1---------------11111111111-------------------------1-----------------1---1------------------------1-11-------------------1------------------------------------------------------------------1-----------------------------1---------------1----------1----------------2-------1-----------------------------------------1---------------1----1------------------------------------------------------------31--2-1---12-11--1-23--1--211---211-------21----------1---2-1-1--111131--12-111211-1211---2-----------------------------------------------------------------1---1---------------1--------------1-------------------------------------------------------- -1--12-11--------------------11-1---1222222-----1-------1--112--------------------2----------11----------1--1-312-----------2--114-1-12-----2--1---1--1---------1-2--11-------2------1---------1---2---
 in family                                    *                           *                          *                                                  *     *                            *       **         *                               *        *                      *        *                        *     *     *                       *       *                     *  *               ***********                         *                 *   *                        * **                   *                                                                  *                             *               *          *                *       *                                         *               *    *                                                            **  * *   ** **  * **  *  ***   ***       **          *   * * *  ******  ** ****** ****   *                                                                 *   *               *              *                                                          *  ** **                    ** *   *******     *       *  ***                    *          **          *  * ***           *  *** * **     *  *   *  *         * *  **       *      *         *   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7614] PF07961            182                                                                                                                                                                                                                          1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
 MBA1:MBA1-like protein         ------------------111-----------------------1----1------------1----- ----------------------------------------------------------------1---------------------1-11------------------------------------1------1--11--------42-11---11-------1---------------1------------------1------11-------------1--------------------------------------1----------------------111------------------------------------------------------------1----11------------1-----------------------------------------------------------------------------------------------------------------111--------------------------------------------------------1--------1------------------------------------------------------------------------------------------------------------1--------------------1-------------------------------------1---------1--1-----------------------------1---------------------------------------1------------------1-----------1----------------------------------------------1--------------------------------------- -----11-----21-212-111112--11-111111121111111121--------11-111111112-1111111111111111211111211-1111--1---1---11-----1-1-----11--11-1-2-11--------1-1----1--1------11-----111111--2------1111---1----12-
                                                  ***                       *    *            *                                                                      *                     * **                                    *      *  **        ** **   **       *               *                  *      **             *                                      *                      ***                                                            *    **            *                                                                                                                 ***                                                        *        *                                                                                                            *                    *                                     *         *  *                             *                                       *                  *           *                                              *                                             **     ** *** ******  ** ******************        ** ********* ************************* ****  *   *   **     * *     **  ** * * **        * *    *  *      **     ******  *      ****   *    ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7615] PF04844            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      212 1        
 DUF623:Protein of unknown fun  ----------------------------1--------------------------------------- -1----------------------------------------------------------------------------------------1--------------------------------1-----------------------1-111-111---1----------111-11112-12----------------------------------------1------------------------1-------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------1-----------------------------------------------------1-------------------------------------1---------------------------------1-----------------1----------1------------------------------------------------------------11--11-1------11-11--1------------------------------------------------------------------------------------1--------------------------------------------1------------------ ----1-1-1---1-------------------------------------1----11------11------1---4-----11-----1---------------11------2-1------------------------------------------1-------1------1---12-1111--8278-781--11--
 ction, DUF623                                              *                                         *                                                                                        *                                *                       * *** ***   *          *** ***** **                                        *                        *                                                                                                 *                                                                               *                                                                                                       *                                                     *                                     *                                 *                 *          *                                                            **  ** *      ** **  *                                                                                    *                                            *                       * * *   *                                     *    **      **      *   *     **     *               **      * *                                          *       *      *   ** ****  **** ***  **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7616] PF10088            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2326:Uncharacterized prote  --------------------------------1--------1---------1---------------1 ------------------------------------------------1---1-------1-----1---1-----1---------------1--------1----2-------------------1--------------------------1-------------1-----------------11------------1----11-1-----1---1-1----11111------------------1---1-1---------11-----1-------111-------------1----1111-1-1111------------11--1---11---1-21-------1-12--121111---1--1---1--1--1------------------------1---1-11------1--------------1-----------1------1----------11--1----------------------------------------1111111-111111--11111111--1-----1----2--1--1-11---------------------------1---11--1-1-2--------1-------------1--------------------------1---------------------------------------------------------------------------21------------------------------------1----1-1--1------1-----------------1121111------------1--------------------------------2----------1111------------------1----------2--------2------------------1-- -----1------11---1----------------------------22--1-----------1------------------------1-------------------2-2----1-----------------------------------------------1-11----11----------------11--21---2-
 in conserved in bacteria (DUF                                  *        *         *               *                                                 *   *       *     *   *     *               *        *    *                   *                          *             *                 **            *    ** *     *   * *    *****                  *   * *         **     *       ***             *    **** * ****            **  *   **   * **       * **  ******   *  *   *  *  *                        *   * **      *              *           *      *          **  *                                        ******* ******  ********  *     *    *  *  * **                           *   **  * * *        *             *                          *                                                                           **                                    *    * *  *      *                 *******            *                                *          ****                  *          *        *                  *        *      **   *                            **  *           *                        *                   * *    *                                               * **    **                **  **   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7617] PF11674            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3270:Protein of unknown fu  ------------------------------------------4-----1-----------1------- ------------------------------------------------1---1-------------------------------------1-----------1-1---------------------------------------11-11-----------------------1-----------------1------------------1---1--1--------------1-11111-11111111----------------11----------121111111111111111111111111111111111-1111111111----2---------1-1----1--11--------------1----2---1--------------1------------------------------------------------1-1------------------------------------------1------1---------------------------------------------------------------------------------------------------------------------1-1111--------------------------1-1--------------1----------------------------------------------------------------------------------------------------------------------------------------------------------1-1------------------------11-------1-1-----------------------------------------------------1------------- 32-1--1---1------2---1---1---------------1-----11-1--1--1-------1----------------223---------2-1--------2---232-------------42--1-------1-----1---------------1-133-12-1--111---2--1--------1-1--1-----
 nction (DUF3270)                                                         *     *           *                                                        *   *                                     *           * *                                       ** **                       *                 *                  *   *  *              * ***** ********                **          ************************************ **********    *         * *    *  **              *    *   *              *                                                * *                                          *      *                                                                                                                     * ****                          * *              *                                                                                                                                                          * *                        **       * *                                                     *              ** *  *   *      *   *   *               *     ** *  *  *       *                ***         * *        *   ***             **  *       *     *               * *** ** *  ***   *  *        * *  *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7618] PF03534            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 SpvB:Salmonella virulence pla  ----------------------------------------------------1--------------- ----11--------------------------------1----1-----------------1--1---1-1----------------------1-11--21---1-------------------------------11-1---1--------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------1---------------------11-------------------------1---------------------------------2--------3----------------------------1----1---------------------------------------------------------151111----11----------------------1----------1-3----2-1-----------------2-------6--------------1--------1-1---11---2------12321----31---11-1--------------------------------------------------1----23--2--------1-1--1-----------11111111111----------------------------------------11--411-12-11---1--1-1----------1--------2--------1-----------------23-------------------------------------------------- 1--------------1--1----------1------1---------1--4-41311--------1--------1-2--------1---------1-111--1-111---2-1-1------1------------------------1-----------1----2--2--1-----------1----11---1----1-1-
 smid 65kDa B protein                                                               *                    **                                *    *                 *  *   * *                      * **  **   *                               ** *   *                                                                                      *                                                                                                        *                     **                         *                                 *        *                            *    *                                                         ******    **                      *          * *    * *                 *       *              *        * *   **   *      *****    **   ** *                                                  *    **  *        * *  *           ***********                                        **  *** ** **   *  * *          *        *        *                 **                                                   *              *  *          *      *         *  * *****        *        * *        *         * ***  * ***   * * *      *                        *           *    *  *  *           *    **   *    * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7619] PF12204            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3598:Domain of unknown fun  -------------------------------------------------------1------------ --1-----------------------------------------------------------------------------------1-11---1------1---11--------------------1-------------1-----414231111123221211111322----------------------------------------------1------------------------------------------------11--------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------1-----------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------1-12111-----------1-------------------------------1----------------------------------1----------------------1----------------1- ----1---1--1-----111---111---1------11-11111--21--11-1---------1----1--1------11-------------1----------2---6-1211------11--111--3-2----1--1--11-----------1---11112---3-----1-1-3-----217333-5632-1--2
 ction (DUF3598)                                                                       *               *                                                                                   * **   *      *   **                    *             *     ************************                                              *                                                **                                                                                *                                                                                                                                                                                                                    *          *                                                                 *                                                                                                                                                      * *****           *                               *                                  *                      *                *      *   *  *     ***   ***   *      ** *****  **  ** *         *    *  *      **             *          *   * ****      **  ***  * *    *  *  **           *   *****   *     * * *     ****** **** *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7620] PF07736            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CM_1:Chorismate mutase type I  ------------------------------------------------------------------1- ---11-------------------------------------1-1-----------------1----1111----------------------------------------------------------------11111---112111111111111111111112111111111111111---11---111---------------111111---11111--11111111------------------------------------------------------------------------------------------1-1--1111111-1-1--------11-----1111-1111121-111-----1--------1---11------------------------------1-----------------------------------------1--------------------------------------------------------------------------------------------------------------------------------1---1111----1----------------------------------------------------------------------------------------------------------------------------------1--1---------------------------------------------------1-1--------------------------111111111--22-------1-----------------------------------1-----------------------------1----------- --------1--------1-----------------1-------2---------------1-1------------------------------------------1-------------1-1------115-4---2-11--112-------------------1------1-13--------------4-----1--1-
                                                                                                  *     **                                     * *                 *    ****                                                                *****   ***************************************   **   ***               ******   *****  ********                                                                                          * *  ******* * *        **     **** ******* ***     *        *   **                              *                                         *                                                                                                                                *   ****    *                                                                                                                                  *  *                                                   * *                          *********  **       *                                   *                             *                    *        *                 *       *               * *                                          *             * *      *** *   * **  ***                   *      * **              *     *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7621] PF03823            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1   1                                                                 
 Neurokinin_B:Neurokinin B      -------------------------------------------------------------------- -1------11--------------------------1----1-1----------------3-----1-2----------------------------------------------------------------------1------------------1---------1--1-----1------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------1----------------1---------1------1----1--1----------1---------11------------------------------------------------------------------1-1----------1----12-----1------------------1------1--------1-------------2-1-----------------------------1-----------------------1--------------------------------------------------------------1------------------------1-----------------------------------1----------------------------1--------1-----------------------------1-------------11-------------------------------------------------1-- --------1-------1----1-----11-----------------1--1------------------------------------------1--1------------2---12-811111322211418-6-046-1322122111-21-12211-1----1-122-11-11---1---------1-1-1------1-
                                                                                                      *      **                          *    * *                *     * *                                                                      *                  *         *  *     *                                          *                                                                                                                                                               *  *          *                *         *      *    *  *          *         **                                                                  * *          *    **     *                  *      *        *             * *                             *                       *                                                              *                        *                                   *                            *        *                             *             **                                                 *           *       *    *     **                 *  *                                          *  *            *   ** *************** * *** ********** ** ***** *    * *** ** **   *         * * *      * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7622] PF11050            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Viral_env_E26:Virus envelope   -------------------------------------------------------------------- ------------------------1---------------------1--------------------------------------------1----------1------------------------------1------------2------------------1-----------1-------------------111--11-1-1----------------------1---------------------------------------1----------------------------------------------1---------111--1-------------1-----------1---------------------------------------------------------------11-----------------1--------------------1-----------------1----------------------1---------------------------------31---------------1----------------1--------------------------11-------11-------------------------------------------------------------------------1-1---------------------------------------------------3-----------------------------------------1-------------------------------1-----------1--------------1-----1---------------------111-1-------------------------------------1------- ----12--1113--1-------------1---1-------------------------1---1---1-----------1---1-11-1---2---1----1--312--11-132-2-132-11-431-13-----4-1--21132-14-----11212322-12-----14-111121--1-21--1----1--11---
 protein E26                                                                                                                 *                     *                                            *          *                              *            *                  *           *                   ***  ** * *                      *                                       *                                              *         ***  *             *           *                                                               **                 *                    *                 *                      *                                 **               *                *                          **       **                                                                         * *                                                   *                                         *                               *           *              *     *                     *** *                                     *            **  ****  *             *   *                         *   *   *           *   * ** *   *   *    *  ***  ** *** * *** ** *** **     * *  ***** **     ******** **     ** ******  * **  *    *  **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7623] PF09078            182                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CheY-binding:CheY binding      -------------------------------------------------------------------- -------------------------1------------------1---------------------1----------------1-----------------------------------------------------------------------------------------------1-------------11111------1---------1--------------------------------1---------------------------------------------------------------------------------------------------------------1----------------------------1--------------------------------------------------------------------------------------------------------------111112111111111122111111111111111--111---------1-32-1212----------1----------1---------1-------------------------------------------1-----1-----------------------------------21111111111111111-11-1111111111111111---1111111111111111111111-1-1111--111111111111----------------1--------------------------1------------------------------------------11----------------------------------------------------------1--11-1-----1- --------------------------1-----1---1----1----1----------1------------------1-------------1---1------------1-----------11------------------1--------------1-----1----2----1-111------11--1-----1---1---
                                                                                                                              *                  *                     *                *                                                                                               *             *****      *         *                                *                                                                                                               *                            *                                                                                                              *********************************  ***         * ** ****          *          *         *                                           *     *                                   ***************** ** ****************   ********************** * ****  ************                *                          *                                          **                                                          *  ** *     *                            *     *   *    *    *          *                  *             *   *            *           **                  *              *     *    *    * ***      **  *     *   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7624] PF10071            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2310:Zn-ribbon-containing,  ----1--------------------------------------------------------------- ------------------------------------------------------------------------------------------2--1----------1------------------------------------------1---------------------------------------------------1-------1-----------------------------------------------------------4-------------------------11-11----------------------------------------11-----------------1-------------------------------------------------------------------111-------------------------------------------------111121---1--------------------------------------------------------------------------------5-----------1-1-------------------1---1-----------------------11-------111121111111111111111------1----------------------------------------------11--------------------------------------------1-----------1--11111111211-111---------1-1---------------------------11111111121111----1-----1--------------------------------------------------------------- --------1----------11--1-1------1---1111111----1---------------------1-------12--------1-----1-1--------1----1-21111-11-1-1-21---7-6-221----1--1-11--11-----2---1--2-6-3-----31----------------1-------
  possibly nucleic-acid-bindin      *                                                                                                                                                          *  *          *                                          *                                                   *       *                                                           *                         ** **                                        **                 *                                                                   ***                                                 ******   *                                                                                *           * *                   *   *                       **       *********************      *                                              **                                            *           *  *********** ***         * *                           **************    *     *                                                                        *          **  * *      *   *******    *                     *       **        *     * *        *    * ***** ** * * **   * * ***    *  * **  **     *   *  * * *     **                *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7625] PF07866            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1653:Protein of unknown fu  -------1-------------------1---------------------------------------- ----------------------------------1----------------------------------------------1-------1---------------1--------------------------------11-------------------------------------------------------------1-----------1-------------------------------------1-----------------------------------------------------------------------111------111-1-5---1111-----11-----1-----------------------------------------------------------1-----1-----------------------11111111-11------------1--------------2------------1111-11111111---111111-1-111111111-11111111111-1-11---1-1--------------1---1-1----111-11111-111--------1-----------------------1--11-11111112-----1----------------------------------------------------------------------------------------------------------------1------11--1111---------------11111111111111111-11111111111------------------------1111111---------1--------------------------------------------------------- ----------1------1--------1--1----1----------------1--------------------------------------1----2------------2--1---1--------------------------------------------------1---11----------------2-----11---
 nction (DUF1653)                      *                   *                                                                           *                                              *       *               *                                **                                                             *           *                                     *                                                                       ***      *** * *   ****     **     *                                                           *     *                       ******** **            *              *            **** ********   ****** * ********* *********** * **   * *              *   * *    *** ***** ***        *                       *  ** ********     *                                                                                                                *      **  ****               ***************** ***********                        *******         *                                                                    *      *        *  *    *                *                                      *    *            *  *   *                                                  *   **                *     **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7626] PF11675            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                2                                                                                                                                                                                                  
 DUF3271:Protein of unknown fu  --------------1--1---------------1--1----------1-------------------- ---------------------------------111-------------------------------------------------1--11----------1---11-------------1---1--------------------------------------------------------------------1-------------------------1------11---------1--------------1-----------------1--------111-------------------------------1------------1--1---1-12-1-------------------1---1---------------------1-----------------------------------------1-------------------1--------------------------------11------------------1-------------------------------------------------------------------------1--------------------------1-------------------------------------------1--------------1---------------------------------------------------1----1-2---22-2211----1-----------11--1111---------------1-----------------------1--1---------------------------------------------------------------1--1111-----------------------1------1-----------------1- -6--04--1-1-------------------------------------1----------------------1---1---1-----------1----1------11----1121-12-12--111111212-2-122111-11212-1-2-111-1111--111---1---2-2------5-----1-------------
 nction (DUF3271)                             *  *               *  *          *                                                      ***                                                 *  **          *   **             *   *                                                                    *                         *      **         *              *                 *        ***                               *            *  *   * ** *                   *   *                     *                                         *                   *                                **                  *                                                                         *                          *                                           *              *                                                   *    * *   ** ****    *           **  ****               *                       *  *                                                               *  ****                       *      *                 *   *  **  * *                                     *                      *   *   *           *    *      **    **** ** **  ********* * ****** ***** * * *** ****  ***   *   * *      *     *             
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7627] PF10766            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2592:Protein of unknown fu  -------------------2----1-------------------------1------1--1------- --------------------------------1222--11----1---1-----2-----------2-----------------1---1-1--2-------------------------1111----1-----------------1-----1----1------1-------------------------------------------------------------1112--------------------------1-------11-------------------------------------------------------------------------------------1------------------------------------1----11-1--------------1-------------------------11-------------------------------------------------------------------------------------------1----------------1------1------------------1-----------------------1--------1-----------------------------1-11---------------------------------11121111111111-11-1111111111111--11-1111-1-111111211111111111211111111-111111111111--1------------------------------11111----------------------------------1-----------------1--111------1----------------------1---------------------------------- ---11----------2--1------------------111-----1-1----1----------------------------------------------------------11-----1----------------1---1--1--------------1------11----1-1-------11----11--1---1----
 nction (DUF2592)                                  *    *                         *      *  *                                        ****  **    *   *     *           *                 *   * *  *                         ****    *                 *     *    *      *                                                             ****                          *       **                                                                                     *                                    *    ** *              *                         **                                                                                           *                *      *                  *                       *        *                             * **                                 ************** ** *************  ** **** * *************************** ************  *                              *****                                  *                 *  ***      *                      *                                      **          *  *                  ***     * *    *                                                          **     *                *   *  *              *      **    * *       **    **  *   *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7628] PF10784            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               1                   
 Plasmid_stab_B:Plasmid stabil  -------------------------------1--------------------------------1--- ----1------------11-1-----11111-1----------1--1-1-----1------1----1------------------------------------11--1------------------------------------1----------------1--------------------11-----------------------1-----------------------1---------------------------1---------------------------------------------------------------------------------1------------1------------1-----------------1111---------11----111--12-21112-----21--1--1------1--1---------------------------------------------------------------1---1----11-------21---------------2-----1----12----------------1--------------------------1--1-1-----------------------------------------------1--11--1----------1--------2---2-11--2-12-----112---21--------411----2----11--11-1---1--221-------------------------------------------------------------------1---------------------1------1---------1-11----111------1------------------------------------------1---------- -1---------1---1--------------1--2---1111------------1-1-------------------2--------------------------------311--11-2------------1---1------------------------1----1------4-----11-4---1--121---------1
 ity protein                                                   *                                *        *            ** *     ***** *          *  * *     *      *    *                                    **  *                                    *                *                    **                       *                       *                           *                                                                                 *            *            *                 ****         **    ***  ** *****     **  *  *      *  *                                                               *   *    **       **               *     *    **                *                          *  * *                                               *  **  *          *        *   * **  * **     ***   **        ***    *    **  ** *   *  ***                                                                   *                     *      *         * **    ***      *                                          *            *         *   *              *  *   ****            * *                   *                                ***  ** *            *   *                        *    *      *     ** *   *  ***         *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7629] PF06718            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1203:Protein of unknown fu  --------------------------------1----------------------------------- ---------------------------------------------------------1------1--111------------------11----------------------------------------------------------------------------------------------------1--222221121112121------111----------------------------------------------11------------------------------------------------------------------------4----------------------------------------1-------------------------------------1-1--111111211112--1-1-1-----111-----------------------------------------1-----1-1-------11---------------------------------------------1--1------------------------------------------1-------------------------------1----------1111-1-1111-1--1-----------------------------------------------------------------------------------------------------------------------------------------------------11-------11------------11----------11------------------------------------------------------------------------ -----------1--1----1-------------121-111122----------------------------------1-1-------------------------3-----44121----1-1-3117-7-1-515---11111--1---11121411----12-1----1---1------------------------
 nction (DUF1203)                                               *                                                                                             *      *  ***                  **                                                                                                    *  ***************      ***                                              **                                                                        *                                        *                                     * *  ************  * * *     ***                                         *     * *       **                                             *  *                                          *                               *          **** * **** *  *                                                                                                                                                     **       **            **          **                                                                                    *  *    *             *** ******                                  * *                         *     *****    * * **** * * ***   *****  *   ********    ** *    *   *                        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7630] PF07485            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1529:Domain of Unknown Fun  ---------------------------------------------1-----2---------------- -22-11-----------44-4-----44444-------2--------------12------------------------------------2----------------------------------------------11---------1------------------------------------------2-----121--1-2--1-11----1--1----------52---------------------------------------------------------------------------------------------1-2222112-2---11-----2-------------------------------------4-4-22-------------------2-2--42--------1--1----1-------------------------------------------------------------2----1------------------2-222---8----2------1---------------------------5-------------------------1---1-3--------------------------------1----------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------1----1--------------------------------1------------2-1-12---1---1------------------------------11----2-11--1-1-----2------------2--3--11--111-
 ction (DUF1259)                                                             *     *                  ** **           ** *     *****       *              **                                    *                                              **         *                                          *     ***  * *  * **    *  *          **                                                                                             * ******* *   **     *                                     * * **                   * *  **        *  *    *                                                             *    *                  * ***   *    *      *                           *                         *   * *                                *                                                                                  *                                                                                                                                                                                                                                                                  *    *                                *            * * **   *   *                              **    * **  * *     *            *  *  **  *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7631] PF07841            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 3 3222                            
 DM4_12:DM4/DM12 family         -------------------------------------------------------------1-1---- -------------------------------------------------------------------------11------------------------1-----------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------111-111---1-----------------------1----------------------------1--1--1-----------------1-------------------------------------------------------------------------------------------------------------1--------------2------------------------------------------------------------------1--------------------------------------------------------2-----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-1------------------------------------------------------------------------------- --------------1-----1------------------------------------------------------------11------------------1--1----11---1--------------------------------1------------111--268211----------------------------
                                                                                             * *                                                                              **                        *                                               *                                                                                                                                     *                                             *** ***   *                       *                            *  *  *                 *                                                                                                             *              *                                                                  *                                                        *                                                                                                                                                                       * * *                                                                                              *     *                                                            **                  *  *    **   *                                *            ***  ******                            
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7632] PF09666            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Sororin:Sororin protein        -------------------------------------------------------------------- --1----------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------11--1-------------------------------------------------------------------1--------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------1------------------------------2--------------1----1----------------------1-----------------------1----------1-------------------------------1-------------------1--------------1----1-1111111211-111111111111111111111111-1-1111111111111111-1111111---------------------------------------------------------------------------------1--------------------------11---------------------------------------------------------------- ----------------221------------1----1-------------121----2-1---1---1-----------1--------1--121-------1---3--1--211-11211112211-112-2-11212122-111-111112-11--13------41-1--112---2-------2111-11-2-----
                                                                                                       *                                  *                                                                                                                                                                     **  *                                                                   *                                                                                                  *                                                                                                                         *                              *              *    *                      *                       *          *                               *                   *              *    * ********** ************************ * **************** *******                                                                                 *                          **                                                                                 ***            *    *             ***    * *   *   *           *        *  ***       *   *  *  *** *********** *** * ******** *** ****** **  **      ** *  ***   *       **** ** *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7633] PF11956            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 KCNQC3-Ank-G_bd:Ankyrin-G bin  -------------------------------------------------------------------- --------------1--------------------------1---------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------1------1----------------1----------------------------------------------------------1-------------------------1----1------------------------1---------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------1--------- ----1---1---------1------------1-----2211111--2--1--------------1-----11-----------------1-2-1-------1--------1232315-22122144-422-5-42711222222112223411624222----2--1--1---1--1--1-----115111---31-1-
 ding motif of KCNQ2-3                                                                                             *                          *                                                                                                                     *                                                                   *                                                                                                                                                              *                        *      *                *                                                          *                         *    *                        *                                                                                 *                                                                                                                                                                 *                                                                                                              *              *   *         *            *     *******  *  *              *     **                 * * *       *        ******* ******** *** * **************************    *  *  *   *  *  *     ******   ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7634] PF12185            181                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 IR1-M:Nup358/RanBP2 E3 ligase  -------------------------------------------------------------------- ------------------------------------------------------------1--------------------------------------1-------------------------------------------------------------------1---------1-------------------------------------------------1-----------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------111--------------------1-------11----------------------------1--------------------------1-------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------1-----------------------1---------------------------------------------------------------------------------------------------------- --------1-2----1-1--------11112--------------11-1-1---11--1111-----------1----------------2----------1-112--114243-3423412323222-4-2-22221222-222232224214--333-2211-1131-114------------312---1-11-1--
  domain                                                                                                                                                         *                                      *                                                                   *         *                                                 *                                         *                                                                                                                                                  *                                                                                               ***                    *       **                            *                          *                                                                                                             *                                                                         *                       *                                                                                                                   * *    * *        *****              ** * *   **  ****           *                *          * ***  ****** ************* * * ******** ************  *** **** **** ***            ***   * ** *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7635] PF06695            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Sm_multidrug_ex:Putative smal  111111-1---------------1--1---1---------1--1123131-11-1111111------- ----------------------------------------------1-----------------1----------------------------1------------1---------------------------------221-----------11---------1-1-------------1---1111-1--------1-1---11-22111-1-1----1--------2-----------------------------------------------111------1---------------------------111-----21--1112231-3--1--1----1--1112-1-----112--13--1-1-----------------1-------------------11-11--------------11-------------------------------------------1----------------1--1-1--------1111111----11--------1--------------------1-------------------------1-------1------------------1--------------------------1--11---1---------------------------1112------1--------------------------------------------------------------------------------------------------------------------------------------------------------------11111----------------------1--------11--11------------------------------------------ ----1----------------------------------------------------------------------1--------------1--111-----1--------4-----------------------------1-1--------------------------------1---------2121-1111----1
 l multi-drug export protein    ****** *               *  *   *         *  ******* ** *******                                                      *                 *                            *            *                                 ***           **         * *             *   **** *        * *   ** ***** * *    *        *                                               ***      *                           ***     **  ******* *  *  *    *  **** *     ***  **  * *                 *                   ** **              **                                           *                *  * *        *******    **        *                    *                         *       *                  *                          *  **   *                           ****      *                                                                                                                                                              *****                      *        **  **                                               *                                                                      *              *  ***     *        *                             * *                                *         **** ****    *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7636] PF02971            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 FTCD:Formiminotransferase dom  -------1-----------1---------------------------1-----------1-111---- 1111-------------------------------------------------------------------------------1-2--1111-111-----1-----------------------------------------1---------------------------------------------1------------------1------------------------------------------------------------------------1-1-1-------------11131111111111----------24---------------------1---1-----------111111-12-1-------------------------------------------------1-------------------------------------------------------1------------------------------------------------------------------------------------------1--2-1-------------------------1----21-------1----------------------------------------------------1------------------------------------------------------------------------------------1-------------------------------------1-----------------------1----------------11111-------------------------------------2------------------------1111111111111---- 2---11-------------------------------------------------------------------------------------------------1------31211131----1111-116-2-21211111121---1111---1111112222111------2--1-1----112--3-211-----1
 ain                                   *           *                           *           * ***     ****                                                                               * *  **** ***     *                                         *                                             *                  *                                                                        * * *             **************          **                     *   *           ****** ** *                                                 *                                                       *                                                                                          *  * *                         *    **       *                                                    *                                                                                    *                                     *                       *                *****                                     *                        *************     *   **                                                                                                 *      ********    **** *** * ***********   ****   *************      *  * *    ***  * ***     *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7637] PF06784            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 UPF0240:Uncharacterised prote  --------111111-----------------1---------------1-------------------1 -1-----1------------------------------------------1-----------------------------------1------------------1--------------------------------------------------------------11----------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------1---------------------------------16------------------------------------------1--------1--------1----------------------------------------1-----------------1------------------------------------1------------------------------------------------------------------------------------------------------------------------------------1-------------1-----------------1------------------------------------------------------------1-----1--------1-------------------------------1--------- -----11-42-1--11-1------1-1------1-------------1-----1--1------11---------1-1--------1-1-1-1---1-----2-223----411114-121221-221121-1-112112-21131111-1111111321-1132111121111211-11------22321----2131-
 in family (UPF0240)                    ******                 *               *                   *  *     *                                          *                                   *                  *                                                              **                                              **                                                                                                                                   *                                                                                          *                                 **                                          *        *        *                                        *                 *                                    *                                                                                                                                    *             *                 *                                                            *     *        *                               *               ** ** *  ** *      * *      *             *     *  *      **         * *        * * * *   *     * ***    ****** ****** ****** * ****** ******** ********** **************** **      *****    **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7638] PF06372            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Gemin6:Gemin6 protein          --------1111111-------------------------------------1--------------- -1---------------------------------------------------------------1--------------------1---------------1--------------------------------------------1---------------------------------------------------------1-------------------------1--------------------------------------------------111---1---------------------------------------------1---111-----------1--------1--------1---1---------------------------------------1-------------------------------------------------------------------1----------------------111---------2-------------------------------------------------------------------1---1---1-------------------------------------------1----111------1----1--------------------------------------------------------------------------------------111111111111---------------------1----------------------------------------------------1--------1----1-------------------------------------------------------1--------------- -2--1----1------1-----1------------------11-----1-----1--------1------------1-1---------1--11----------111--2-2-211111-1121-223215-2-2241-13211111111121-1111122-3112211-111111---13211-----1-1---1121-
                                        *******                                     *                 *                                                               *                    *               *                                            *                                                         *                         *                                                  ***   *                                             *   ***           *        *        *   *                                       *                                                                   *                      ***         *                                                                   *   *   *                                           *    ***      *    *                                                                                      ************                     *                                                    *        *    *                                                       *                 *  *    *      *     *                  **     *     *        *            * *         *  **          ***  * * ****** **** ****** * **** ************** ******* ******* ******   *****     * *   **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7639] PF08101            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1708:Domain of unknown fun  ---------111-------------------------------------------------------- ------------------------------------------------------------------------------------1---1---------------------------------------1---------------1--1111---------------------1--------------------------------------------------1-----1------------------------1------------------------------------------------------------------------------------------------1---------------------------------------------------------------1--------1----1----1----------------------------------------------1----11-------------------------------------------------------------------------------------1------------------1----------------11------------------11--------1------1---------------------1-------------------------------------------------------------------------------------------------------------------1--------------------------1---------------------------------------------------11-------------------------------------------------- --------2------1111211111211111112-111111111111121121111112112112222-1111111111121111121121313331111223-1--1-2--1-----1-1-------------------1----------1-1---211--1--14--------1------------111---2211-
 ction (DUF1708)                         ***                                                                                                                                             *   *                                       *               *  ****                     *                                                  *     *                        *                                                                                                *                                                               *        *    *    *                                              *    **                                                                                     *                  *                **                  **        *      *                     *                                                                                                                   *                          *                                                   **                                                           *      ******************* ********************************* ********************************** *  * *  *     * *                   *          * *   ***  *  **        *            ***   **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7640] PF12116            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 SpoIIID:Stage III sporulation  -------------1-1-----1--------------------------1------------------- ---------------------1-----------------1------------------------1-11--------1-----------------------------------------------------------------31----------------------------------------------11111111211111111111111112111111--------11------------------1-----------------------------------------------------------------------211111111132131-12211111-1--1312111221121111111----------------------------------------------------1----------------------1--------------------------------1--------------------------1-----------------------------------------------1----------------------------------1-----------------------------------------------1----------2------1-------1--------------------2--------1-------------------------1-1----------------------------------------------------1-------------------------2------------------------1-------------------------------------11------------------------------1--------------------- ----11------------11-------------------------------------1------1---------------------11---1-------1---1-5---1-1-11---------1------------------------1-------2-25-11111---2--1----1---------2-1----13--
  protein D                                  * *     *                          *                                         *                 *                        * **        *                                                                 **                                              ********************************        **                  *                                                                       *************** ******** *  *******************                                                    *                      *                                *                          *                                               *                                  *                                               *          *      *       *                    *        *                         * *                                                    *                         *                        *                                     **                              *                          **            **                                     *      *                     **   *       *   * *   * * **         *                        *       * ** *****   *  *    *         * *    **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7641] PF11750            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3307:Protein of unknown fu  --------------1--------------1-----------------------------------11- ------------------------------------1----1-11----------------------1------------1-------------------1-11-11-1-----------------------1---------------------11---11--------------------------111-----------1-1--1-1-------1--11-2--------1----1--1--------11-------------------1--------1111111111-----------1----111111-1111---1111-1---------------------------------111-4-----1--2-1--1----------11111-11111----------1---1-1-11-1--------1--1----1---1-----111---------------------------------11---------------------111111-----11--------1-------1-------------------1-------------------------1----------------------------------------------------1---111-1-----11----------------------------------------------------------------------1-----1--------2------------------------111111-------1----------------111111-----------------------------------------------11-----------------------------------------------1----------1112111111---3 -1-----------1--------1------------1---------------1--------------1--1-----1---1-----------1--1----------------------1--1----------1----------------1-------1---1--1---1----1------1--------1----------
 nction (DUF3307)                             *              *                                   **                                      *    * **                      *            *                   * ** ** *                       *                     **   **                          ***           * *  * *       *  ** *        *    *  *        **                   *        **********           *    ****** ****   **** *                                 *** *     *  * *  *          ***** *****          *   * * ** *        *  *    *   *     ***                                 **                     ******     **        *       *                   *                         *                                                    *   *** *     **                                                                      *     *        *                        ******       *                ******                                               **                                               *          **********   *  *           *        *            *               *              *  *     *   *           *  *                      *  *          *                *       *   *  *   *    *      *        *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7642] PF10222            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         1                         
 DUF2152:Uncharacterized conse  ----------------1--------------------------------------------------- -------------------------1-------------------------------1--------------------------------1-----------1------------------------------------------------1--------------1---------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------11-------------------------------------------1----------------------------------------------1--------1--------------------------------------------1--------------------------------------------------------------1-------------------------------------------------------1----------------------1----------------------------------------1---------1---------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------11------------------------------------------------1--- ----1211----11--1----------1--11-----111----1----1-----------------------------------------11-------1------2-1621232111--211311116-3141611-132121-11--1-11-21123443723335321102-----------11--------1-1
 rved protein (DUF2152)                         *                                                                             *                               *                                *           *                                                *              *                                                                                 **                                                                                             **                                           *                                              *        *                                            *                                                              *                                                       *                      *                                        *         *                                                                                                                                                         *                        **                                                *        ****    **  *          *  **     ***    *    *                                         **       *      * **********  ********* ******* ****** **  * ** ********************           **        * *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7643] PF10292            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       33                          
 7TM_GPCR_Srab:Serpentine type  -----------------1----11--------------------------1----------------- ---------------------------------------1-----------------------------------------------------1------1---1------------------------------------------------------1------------11------1-----------------11---------------------1----------1------------------------------------------------------------------11-111-1111-1-------------1-6-64224--------------------------------------------------------------------------------------------------------------------------------------1------1-----1---------------------------------------------------------------------------------1----------1-----------2-------------1-1-----------------------------1------1-------1------11-1---1---------------------------------------------------------------1---------------------------------1--1---------1----------------------------------------------------------1-11------------------------11-----------------------1-----------------------------1 --1-------2----1-1----2---------------------1-11-1---------1---------------11-11---------------1--------11---11-----1-------------------------1--------------1---12-2-----2311-------------21----1-11--
  7TM GPCR receptor class ab c                   *    **                          *                                                         *                                                     *      *   *                                                      *            **      *                 **                     *          *                                                                  ** *** **** *             * * *****                                                                                                                                      *      *     *                                                                                 *          *           *             * *                             *      *       *      ** *   *                                                               *                                 *  *         *                                                          * **                        **                       *                             *   *       *    * *    *                     * ** *         *               ** **               *        **   **     *                         *              *   ** *     ****             **    * **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7644] PF09869            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2096:Uncharacterized prote  -------------------1-------1----11111111111----------1--1---1------- -----------------------------------1----------------------------------------------------1211-----------------------------------------------------11----------------------1-----------------------------------1--1----11----1--------11-------------------------------------1---------11-1-------1-------1-------------------------1---2------------------------------------1---------1-------------------1--1--------------1------1-------------------1--------------------1---------------1-------------------------------------------------------------------1-------------111-------1----1---------------------------------1-------1-111------------1---1-------------------1---------------------------------------------------------------------------------------1111-11111------11-11----------------------------------------------------------------111--------11---------1------1---------------2---------1--------------111---1---------1 1--1----------11-------------------1-211121---11---11--------11--------1-121-----11--1-------11----------1---23----4------1-21-1-8-1111--1--1----1--1-----1---1-1232-31---11--1---------1-112----1-2-1-
 in conserved in archaea (DUF2                     *       *    ***********          *  *   *                                           *                                                    ****                                                     **                      *                                   *  *    **    *        **                                     *         ** *       *       *                         *   *                                    *         *                   *  *              *      *                   *                    *               *                                                                   *             ***       *    *                                 *       * ***            *   *                   *                                                                                       **** *****      ** **                                                                ***        **         *      *               *         *              ***   *         * *  *          **                   * ******   **   **        **        * ***     **  *       **          *   **    *      * ** * * ****  *  *    *  *     *   * **** **   **  *         * ***    * * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7645] PF02278            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Lyase_8:Polysaccharide lyase   ---------------------------1---------------------------------------- -1--2----------------------------------------2------1-1--------11--111------------------113-----------------7-----------------------------------1-------------------------------------------------------11-----------------------------1-11121121111111---1-2---11----------1---------11111-1---1111111111111111111111-1-22-----------------111--------111-------------------------------------------------------------1----------------------1-----------------------------------------------------------------------------------1------1---------------------------------------------------------------------------------------------------------------------------1-------------------1----------2---------------------------------------2-1-------------------------22222222222------------------------------------------------------------1------------111--------24-----------------------------------------------------------------------1-- -1111-4----4------1-----------------1-----1----112------1--------------------------------1-1-111-----1-2111-----------------1----------------------------------1--1--1-------6-----11-------1----1-----
 family 8, super-sandwich doma                             *                                          *  *                                        *      * *        **  ***                  ***                 *                                   *                                                       **                             * **************   * *   **          *         ***** *   ********************** * **                 ***        ***                                                             *                      *                                                                                   *      *                                                                                                                           *                   *          *                                       * *                         ***********                                                            *            ***        **                                                                       *    **** *    *      *                 *     *    ***      *                                * * ***     * ****                 *                                  *  *  *       *     **       *    *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7646] PF11854            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         1                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
 DUF3374:Protein of unknown fu  ----------------------------1--------------------------------------- 1-1----------------------------------------------2------------------------------------1-------------1-2------------------------------------------1--------------1------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-----1------------------------------2--1------------112--2--------------1--1---------------------1-1----------------------1----------------------------------11------2-----11111----1111----1-2-2--11--1------1---------11-1---------11--2--1---------1-3--12------------------------------1------1-------11-22232-3324412453202-----1-------------------------------------------------------------1-1-11-----------------------------------1----------------1-------------1----21----1111-------------1-21------11-11--22-22-------------------------------------------------------------1--1-- -----------------------------1111----------1-------------------------------------------------------1----------------------------1----1-1-----------------1---1---------------1--1-----------1--1--131--
 nction (DUF3374)                                           *                                        * *                                              *                                    *             * *                                          *              *      *                                                                                                                                                                          *     *                              *  *            ***  *              *  *                     * *                      *                                  **      *     *****    ****    * * *  **  *      *         ** *         **  *  *         * *  **                              *      *       ** ***** *************     *                                                             * * **                                   *                *             *    **    ****             * **      ** **  ** **                                                             *  *                                ****          *                                                       *                            *    * *                 *   *               *  *           *  *  ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7647] PF08891            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 YfcL:YfcL protein              ------------------------------1------------------------------------- -------------------------------------------------1---1------------1-----------------------------------------------------------------------1--------1-------------------------------------------------------------1--------------1--------------------------------------------------------------------------------------------------------------------------1--------11-----------------------------------------------------1--1----1----------------------------------------------------------------------------------------------------11-------------------------------------------------1---------------------1----1----1-1-----1-----------------11-1--111111111111111111111112-------------11111111211111111-2111112111111111111111111111111111111111111111111111-111111111111---1-----------1-1--------------------------1---------1-----------------11111111111111--------------------------------------------------------------1--1---1---- ----111----------1-----1----------------------1----------1---------------1----------1---2--1-2-1-------1----2-------------------------------------------------2------11-----------------11-------------
                                                              *                                                                                       *   *            *                                                                       *        *                                                             *              *                                                                                                                          *        **                                                     *  *    *                                                                                                    **                                                 *                     *    *    * *     *                 ** *  ************************             ***************** **************************************************** ************   *           * *                          *         *                 **************                                                              *  *   *         ***          *     *                      *          *               *          *   *  * * *       *    *                                                 *      **                 **             
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7648] PF11454            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            1                                                                                      
 DUF3016:Protein of unknown fu  -------------------------------1------------------------------------ ----------------------------------------------------------------------------------------------------------------------------------------------------1--1------------------------------------------------------------------------------1---------------------2--------------------1----------------------------------------------------------------------------------1--1------------------------2-----1------------------11-11-121----------------------1---------1-----------------------------------------1---------------------------------1---1--------1111---------1-1------------11----------------------1-1-----2--------------------------------1--1111-1111111211111121112---------------------------------------------------------------------------------------------------1-----------------------------------1---1-----1-----1-----------------------------11121211111--------11---------------------------------------------------2-- ----1----------212111111121----1--1--123211---211111-1111111111--1----11-------------1--11--1---111------1-----201---1---1-----1------1---------3----------21-----1--212---112----------1----2-2-------
 nction (DUF3016)                                              *                                                                                                                                                                                         *  *                                                                              *                     *                    *                                                                                  *  *                        *     *                  ** ** ***                      *         *                                         *                                 *   *        ****         * *            **                      * *     *                                *  **** *******************                                                                                                   *                                   *   *     *     *                             ***********        **                                                   *       *          ************    *  *  ******   ****** **********  *    **             *  **  *   ***      *     ***   *   *     *      *         *          **     *  ***   ***          *    * *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7649] PF12069            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3549:Protein of unknown fu  -------------------------------1------------------------------------ ------2-------1---------11---------------3---------------------1----1--------------1------1-----------------1--------------------------------------1--------------1---111--------1--------------------1---------------------------------------------------------------------------------------------------------------------------1-------------1--------------------------------------------------1----------------------------1----------------------------------------11-------------------11------------------1-------------------------------1-----------1-------------------------1-1---1----------1-1------------------------------------1----11-1--111111111111211121121211----------------1----------1------------------------------------------------------------------------------------11-----------------1-------1-11-1----1----1-------------11111111111111----1---------------1111----------------------------1--------------------- 1----1--3----1--------1--------------11111-------2-21----1------1-----1-1-1------------1-2------111----1------9-11111------------2----------2--1----------1--1-------9-21-2-1-------------1--2---11512-
 nction (DUF3549)                                              *                                           *       *         **               *                     *    *              *      *                 *                                      *              *   ***        *                    *                                                                                                                           *             *                                                  *                            *                                        **                   **                  *                               *           *                         * *   *          * *                                    *    ** *  ************************                *          *                                                                                    **                 *       * ** *    *    *             **************    *               ****                            *                      *    *  *    *        *              *****       * **    *      *     * * *            * *      ***    *      * *****            *          *  *          *  *       * ** * *             *  *   ***** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7650] PF06338            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 ComK:ComK protein              --------------------------------------1----------------------------- -1---------------------------------------------------------------1-------------------------------1----------------------------1----------------------13----------------------------1-----------11122222222222222--11112222212222211111--22222222212222222222-------1---11--111------1----------------1-1----------------------------1-----------------------11-------------------1------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1-----------------------------1---------------------1------------------------------------------------------1-----1---------------------------------------------------1---1----1---------------------------------------------------11---------1----------------------------------11---1---------------------------------- -----2------11-----------------11--------11-------21----1-1111-------------1-1----------------1-----11---1------------------1--------1---------------1--1-----21-----21----11-1-----------1-1-12-------
                                                                      *                               *                                                               *                               *                            *                      **                            *           *****************  ********************  ********************       *   **  ***      *                * *                            *                       **                   *                                                *                                                                                                                                                                         *              *                             *                     *                                                      *     *                                                   *   *    *                                                   **         *                                  **   *                                        *      **                 **        **       **    * ****             * *                *     **   *                  *        *               *  *     **     **    ** *           * * **       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7651] PF08138            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Sex_peptide:Sex peptide (SP)   ---------------------------------------------------11---1----------- -11----------------------------1------1---------------------11---------------------------1--------------1--------------------------------------1-1----1-2-111---1--1-----11-----------------------------------1-----1----1-1-------1--------1--1-----------------------------------------------------------1---1-22---1-1-----------------1111-1-1-------1----------11-----------------1-------------------------------------1---------------1---------------------------------------------------------------1---------------------------------------------------1--------------------------------1----1-1-1-----------1-1------------11-------------------------------1----------------1-1------1-------------------1-----1------------------------------------1---------------------1----------1------------------------------------------------------------1--------------------------------11-------------------------------------------------1 -111122----1-11--1---1------------------1-----1-----21-----2---------------------------------------2-11-1-----1----1212111--41-1-2-1-1112---111--1---111-2-112-38-1131-712115------------4112---2----1-
 family                                                                            **   *             **                            *      *                     **                           *              *                                      * *    * * ***   *  *     **                                   *     *    * *       *        *  *                                                           *   * **   * *                 **** * *       *          **                 *                                     *               *                                                               *                                                   *                                *    * * *           * *            **                               *                * *      *                   *     *                                    *                     *          *                                                            *                                **                                                 *  ******    * **  *   *                  *     *     **     *                                       * ** *     *    *******  ** * * * ****   ***  *   *** * *** ** **** ******            ****   *    * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7652] PF11070            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2871:Protein of unknown fu  ----------------------------------------------------------1--------- -----11-11--11-------------------------------11----1--1--------1-----1----------1-------11----------1------------------------------------------------111---------1-------1--------------1--------222222322222232------2-3-11---------1---1111111211111113112----------------------1-------------------------------------1-----------1-----------------11-1-111----------------------------1-----------------------------------------------------1---1------------------------------------------------------------------1----------------------------------------1------------------------------------------------------1--------------------------------1-1---------1------------------------------------------------------------------------------------------------------------------------------1--------------------------------2------------------------------------------------1-------11-1------------------------------------------1------- -----1--21-2-------------------------------------------------------1-------------11-1---------11-------------1311111-11--21-4-1--2-3-132----1-12--1-1--112-2212111-21--------1--------1--------1-------
 nction (DUF2871)                                                                         *               ** **  **                               **    *  *        *     *          *       **          *                                                ***         *       *              *        ***************      * * **         *   *******************                      *                                     *           *                 ** * ***                            *                                                     *   *                                                                  *                                        *                                                      *                                * *         *                                                                                                                              *                                *                                                *       ** *                                          *             *  ** *                                                       *             ** *         **             ******* **  ** * *  * * ***    * **  * *  *** ******* **        *        *        *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7653] PF12127            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 YdfA_immunity:SigmaW regulon   ----------------------------------------------------------------11-- ---------------------------------1----------------------1-------------------------------111111--1--------1-----------------1---------------------1---------------------------------------1112--11------1---1---1111111------12111111111112221111112121111111-----------------1--1------1-------------------------------------------21-1------1-----------1-11111---11-1---1--11-------2------------1-------------------1---1------1-----1---------1--1---1---------------------------------------------------------1----111-11--------------13--------------11------------------------------11-------------------------1---1---111-1--1---------1-----1----1------31--1-----------------1-------------------1-1--------1-----1----------1--------------1----1-------------------------------------------------------------1-------------------1------------------------------------------11-------1---------------------------------1----------111- -1------21-------1---------------1--------------1--1--1---------------------------------------------11-4-4--1------------------------------1-----------------11----2--1--1--1----1-111---211-----------
 antibacterial                                                                                  **                                    *                      *                               ******  *        *                 *                     *                                       ****  **      *   *   *******      ********************************                 *  *      *                                           ** *      *           * *****   ** *   *  **       *            *                   *   *      *     *         *  *   *                                                         *    *** **              **              **                              **                         *   *   *** *  *         *     *    *      **  *                 *                   * *        *     *          *              *    *                                                             *                   *                                          **       *                                 *          ***   *      **       *               *              *  *  *                                             ** * *  *                              *                 **    *  *  *  *    * ***   ***           
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7654] PF11595            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1                    
 DUF3245:Protein of unknown fu  -------------------------------------------------------------------- ---1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------2------------------------------------------------------------------------------------2-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------11------------------------------------------------------------------------ ----1-1-1-2-----131111111111111121221121111522-11--21111-21-1121---1-1-----221-1-----111121111111--2---231-11------5------1-11------------1--------12----21211---1412114--3-3-----04-1---145323-1-1111-
 nction (DUF3245)                                                                                       *                                                                                                                                                                                                                                                                                *                                                                                                                                                                   *                                                                                    *                                                                                                                                                                                                                       *                                                                                                   **                                                                             * * * *     ****************************** **  ***** ** ****   * *     *** *     ************  *   *** **      *      * **            *        **    *****   *******  * *     ** *   ****** * **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7655] PF10536            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      414 1        
 PMD:Plant mobile domain        -------------------------------------------------------------------- ----1-----------------------------------------1---------------------------------------------------------------------------------------------------1-------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------111111-----11---1-----1-----------------1---------------------------------------------------------------------------------1-------------11-1111-1111-1--1---------------------------------------------------------------------------------------------------------11---------------------------------------------------------------1-------------11-------------------------------------------1---------------------------- -----------1-------------------1------------------------------1----1----1------------1--1-----12-----1---1--111--------------------1---1-----1-----------------1--22------1--1------------632-7---1-1--
                                                                                                         *                                         *                                                                                                   *                                           *                                                                                                                                                                                                         *                                                                                                               ******     **   *     *                 *                                                                                 *             ** **** **** *  *                                                                                                         **                                                               *             **                                           *                                        *                   *                              *    *    *            *  *     **     *   *  ***                    *   *     *                 *  **      *  *            *** *   * *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7656] PF05212            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     1 11 1        
 DUF707:Protein of unknown fun  -------------------------------------------------------------------- -----------------11-1---1-111111--------------------1-----------------------------------------------------1-1-----------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------1-----------1---------1--------------------------1--------------------1----------------------------------------------------------------------------------------------1------------------1-----------1------------------1---------------------------------------------1---------------1--------------1-11--------------------11111111111-111111-111111111111-------------------------11111-1----------------------------------------------------------1--------------------------------------------------------------------------------------------------------1------1--- ----111----111--1----------1-----------------------2-1-----111--1-----------1---------------1--------1-1-2-----1----------------------1-------1--------------1-13--1--------21--1117---1-2920-64-1-1-11
 ction (DUF707)                                                                                                       ** *   * ******                    *                                                     * *                       *                                                                                                                                                                                                         **                          *           *         *                          *                    *                                                                                              *                  *           *                  *                                             *               *              * **                    *********** ****** ************                         ***** *                                                          *                                                                                                        *      *        ***    ***  *          *                       * *     ***  *           *               *        * * *     *                      *       *              * **  *        **  ****   * **** ** * * **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7657] PF10631            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 DUF2477:Protein of unknown fu  -------------------------------------------------------------------- ---------------------------------------1-------------1--------1-------------------------------------1---1---------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------1-----------------------------------------------------------------1----------------11--1-----------------------------------------------11---------------1---------1---------------------111111----------------------------------------------------------------------------------------1------------1----------1-----------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1--- --------211----111--1111-1111----1-112222--1--11--1-1-----1-1-----1----------1-1------------1--2-1---2-1-1--3-2--11-2---2-1-231341-8-445--1132111-4-1-2-123221---11--11---1-3---2--------2234--1--11---
 nction (DUF2477)                                                                                                                           *             *        *                                     *   *                                       *                                                                                                                                                                                                                  *                  *                                                                 *                **  *                                               **               *         *                     ******                                                                                        *            *          *                                                                             *                                                                                                                                                            *            ***    ***  **** ****    * ******  *  **  * *     * *     *          * *            *  * *   * * *  * *  ** *   * * ****** * ***  ******* * * * ******   **  **   * *   *        ****  *  **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7658] PF03907            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Spo7:Spo7-like protein         -------------------------------------------------------------------- -----------------------------------------------------1------------------111--------------------------------------------------1------------1--------------------1------------1------------------------------1---1----1-------1--1------2-----------------------------------------------111--------------------------------------------------------1-------3------------------------------------------------------------------------11-------------------------------------11---------------------------------------------------1--------------------------------------------------------------1-----------1-1----------------------------------11-----------1--111---------------------------------------------------------------------------------------------------------------------------1-1---------------------------------------11------------------1-----------------------------1--11------1------------------------------------11--------- --------------21211111111111111211112111111211111111112111-111211111111111211111111111224-112112111-111132----------111---11----1----------------------------------------11--1---1--2----42-11--1--311-
                                                                                                                                                          *                  ***                                                  *            *                    *            *                              *   *    *       *  *      *                                               ***                                                        *       *                                                                        **                                     **                                                   *                                                              *           * *                                  **           *  ***                                                                                                                           * *                                       **                  *                             *  **      *                                    **                        ******************************************** ****************************** ********* ******          ***   **    *                                        **  *   *  *    ** **  *  *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7659] PF12509            180                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   1                                                               
 DUF3715:Protein of unknown fu  -------------------------------------------------------------------- ------------------------------------------------------------------------------------------1--1-------------------------------------------------------------------------------------------------------------1--------------------------2----------------------1------------------------------------------------------------1-----------------------------------------------------------1----------------------------------------------111-----1--------------------------------------------------------------------------------------------------------------1---------------------------1--------------------------------------------1---------------------------1-1-----------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------------------------------- -1-------------1---------------11-------1---------------1----------1-------------11-11----------1-1------1---172-315112122313317-8-2-23011115-221111316225121232--222235---134--------1--------------1-
 nction (DUF3715)                                                                                                                                                                              *  *                                                                                                             *                          *                      *                                                            *                                                           *                                              ***     *                                                                                                              *                           *                                            *                           * *                                                                 *                                                                                                                                          ***                                                                  *             *               **       *               *          *             ** **          * *      *   *** *************** * * ******** ******************  ******   ***        *              * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7660] PF09987            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2226:Uncharacterized prote  --1----2111111---------2--------11333232332------11--3-1-3-------1-- -------1-------------------------111------------------------------------------------1-------------------------111111---1111----------3-11111---1-------------------------------------------11--------1-1-1----1---11--------2------------------------------2---------1------------------------------------------------------------1-1----------1---11----------1-------11--------1-----------------1----------------------------1-----------------------------------------------------------1-----2---11-1111-----------------------------------------1-----------------------1-----11---1---2--------------------------1-1-----------------------1------------------------------------------------------------------------1----------------------------------------------------------------------1----1---1------------------------------------------------2-1---------------------------------------------------------------1-------1--1--------- ----11-----------1--1-------1----1---------1--------1----1-1-1--1--12---11-1-------1-1-------------1---11---1-1-1---1--1---1----11-1-------1----1---1------2-1-31---1-21---1------1--1-1-1--------1----
 in conserved in archaea (DUF2    *    *******         *        ***********      **  * * *       *          *                         ***                                                *                         ******   ****          * *****   *                                           **        * * *    *   **        *                              *         *                                                            * *          *   **          *       **        *                 *                            *                                                           *     *   ** ****                                         *                       *     **   *   *                          * *                       *                                                                        *                                                                      *    *   *                                                * *                                                               *       *  *              **           *  *       *    *         *        *    * * *  *  **   ** *       * *             *   **   * * *   *  *   *    ** *       *    *   *      * * **   * **   *      *  * * *        *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7661] PF09664            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2399:Protein of unknown fu  --111111111111111111121------------------------------11111111---11-- ----2-------------------------------2----111----------------------21-2-----------1-1------11--------------------------------1------------------1-------1----1-1-------------------------------11-------------------------11------------1------------------------111--------11-----------------------------------------------------1-----11-1---1--------------1---11-2-------12-1-------11-----------------------------------------------------12--1---111-111--------------------------------------------------------------------------11-1--1---------1---2----11--1-----------------1-1---------------1--------1-1--11----------------------1---------1----------1----------1------1----------------------------------------------1-------------------------------------------------------1-----------------------------1------------1-------------------------------------------------------------------------------------------------------2-- -1-1----321----------2---------------------------1-----1-11------1-1---11--11111------111-1---1--------1-21-2-1--1-----1--------------------1-1----------3-1---12----21---1----1--3-21-111--1-----1----
 nction C-terminus (DUF2399)      *********************                              ********   **       *                               *    ***                      ** *           * *      **                                *                  *       *    * *                               **                         **            *                        ***        **                                                     *     ** *   *              *   ** *       ** *       **                                                     **  *   *** ***                                                                          ** *  *         *   *    **  *                 * *               *        * *  **                      *         *          *          *      *                                              *                                                       *                             *            *                                                                                                       *    * *    ***          *                           *     * **      * *   **  *****      *** *   *        * ** * *  *     *                    * *          * *   **    **   *    *  * ** ***  *     *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7662] PF12225            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 MTHFR_C:Methylene-tetrahydrof  ---1--------------------------2------------------2211-111-1--------- ---------------------1----------1111-1----------------------------------------------1---------1---------------------------------------------11-----------------2---------------------------11------------------------1-----1-1--1---1-------------------11----------------------------231------------------------------------------2--------------1---------------2111-1---211-------1--------------------------1--1---1----------1--1---------11-----------------------------------------------------------------------------------1---1--------------------------1-----------------------453------------1111112111-1-111-------------------------1-1--1---1-----------111--1----------------------------------------1----------------------------------------1----------------------------------------------------1111111---------1----1111-----------------1-----1------1-----------------------------1--------------------------------------1-- --11-------1----1-1-----1-1------------------------1----11-111-------------1---------------11-1------1--1-----2-1--1-----------11--1---------1----------2--1--1-----311-1---15--11-----12-332-1111-----
 olate reductase C terminal        *                          *                  **** *** *                               *          **** *                                              *         *                                             **                 *                           **                        *     * *  *   *                   **                            ***                                          *              *               **** *   ***       *                          *  *   *          *  *         **                                                                                   *   *                          *                       ***            ********** * ***                         * *  *   *           ***  *                                        *                                        *                                                    *******         *    ****                 *     *      *                             *                                      *     **       *    * *     * *                        *    ** ***             *               ** *      *  *     * *  *           **  *         *          *  *  *     *** *   **  **     ** *** ****     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7663] PF07114            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1370:Protein of unknown fu  -----11--------1--------------1---------------1---1----------------1 ----1--1-------11------------------------1------1--------------1--------------------------1---------------1---------------------------------------1----------------------------------------------------------1------------------------------------------------1--------------------------------------1------------------------------------------------------------1-------------1--------------------------------------------1------------------------------------------------------------------------------------1------------1-11----111111---------11-------------------------------1---------------1-------------------------------------------------------------1---------------1-------------------1------------------1---------1----------------------------------------------1-----------1---------------------------------------------------------------------1--------------------------------------------------------------------------- --11----------------11------11----------------------------------1-------------1----------------3--------------21123132226223222415-2-32322421122323322222112112131112-1112212-1------------------------
 nction (DUF1370)                    **        *              *               *   *                *     *  *       **                        *      *              *                          *               *                                       *                                                          *                                                *                                      *                                                            *             *                                            *                                                                                    *            * **    ******         **                               *               *                                                             *               *                   *                  *         *                                              *           *                                                                     *                                                                              **                **      **                                  *             *                *              ******************** * ******************************** ******* *                        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7664] PF12452            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3685:Protein of unknown fu  -------1-----------------1-----------------------1------------------ --------------------------------1------------------------------------------------------1---1------------1-2------------------------------------1-1111111--11121111111-1111111131121211----------------1--1-----------------------------1----------------11-----------------------------1----1-----------1--------------------------1-1-----------------1-1-----1----------1------------------------------------------------------------------------1-----1111----------------------------1--1111-1---11-1----1---------------1-----------------------1---------------------------------1---1--------------------------------------2--------------------------------------------------------1-------------------------1-----------------------------------------1------------------------------------------------------------------------1--1-----------------1--------------------------------------------------------------------------------1---- -111---1---------------------11-----11-----1-------1-111--------1--1-1--11-1--1--111----1--------------111-------2---1------2--2-3-2-21-1---1--------------111---11-----1-1-121----4211117242-52-----1-
 nction (DUF3685)                      *                 *                       *                                                   *                                                      *   *            * *                                    * *******  *********** ****************                *  *                             *                **                             *    *           *                          * *                 * *     *          *                                                                        *     ****                            *  **** *   ** *    *               *                       *                                 *   *                                      *                                                        *                         *                                         *                                                                        *  *                 *                                                                                *      ***   *                     **     **     *       * ***        *  * *  ** *  *  ***    *              ***       *   *      *  * * * ** *   *              ***   **     * * ***    ********** **     * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7665] PF08505            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DSL1:DSL1                      --------1----------------------------------------------------------- 1-------------------------------------------------------------------1------------------------------1--1------1---------------------------------------------------------------------------------------------111-----------11------------------------------------------------------------------------------------------------------------------------111----------------1------------1--------1------------------------------------1----------------------------------------------------------------11--11---------------------------------------------------1---------------1-----------------1--------------------1--1-------------------------------------------------1---1--1-1-------------------------------------------------------------------------------------------------------------1-------11-------------------1----------------------------------------------------------------------------------------------------1-11-1------------1 ----1-1-3-1-111-211--1-12------1111------21-1-111---1-1131-1-----121--22---212211--1-------12-11-1-1-2--1---12-21-335----11--12112-1-21--22---111112--1--4----231411---2-1--21-----1-----1--2-1-12-111-
                                        *                                                            *                                                                   *                              *  *      *                                                                                             ***           **                                                                                                                        ***                *            *        *                                    *                                                                **  **                                                   *               *                 *                    *  *                                                 *   *  * *                                                                                                             *       **                   *                                                                                                    * ** *            *     * * * * *** ***  * **      ****      ** * ***   * **** *     ***  **   ******  *       ** ** * * *  *   ** ** ***    **  ***** * **  **   ******  *  *    ******   * *  **     *     *  * * ** *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7666] PF02341            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 RcbX:RbcX protein              --------1---11--------------------1--------------------------------- --------------1---------------------------------------------------------------1----------------------1--1----------------------------------------11111111111------11111121-1--------------1------11111111-111111------11--------------1----------------------1------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------1----------------------------------------------------11-------------------------------------------1-----------1---------------------------------------------1---------1--------------------------------------1111111111-11111-111111111111--------------------------11-111-2-----------------------------------------------------------------------------------------------------------------------------------1----------------------------------------- ---11-------------------------------1111111------1---------1---------------------------2---------11--1--------------------1-12---2-----------------------------------21--2------3345874433343-221------
                                        *   **                    *                                                *                                                               *                      *  *                                        ***********      ******** *              *      ******** ******      **              *                      *                                                                                                                                          *                                                                                 *                                                    **                                           *           *                                             *         *                                      ********** ***** ************                          ** *** *                                                                                                                                   *                                             **                               *******      *         *                           *         **  *                    * **   *                                   **  *      ************* ***      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7667] PF07560            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1                                                                                                                                                                                          
 DUF1539:Domain of Unknown Fun  ------------11------------------------------------------1----------- -------------------------------------------------------------------------------1---1------------------11------------4441111------------------------1-------------------1----------11----1----------------1---------------1------------1-----------------------------1----------------------------------------------------------------1--------------------1--------------------------------------------------------------------------------------------------------------------------------1-----------------------1---------------11---------1-----------1----------1---1--1--1-------------1-----------1-11---1---------------------1--------------------------------1-----------1-------------1-----------------------------------------------------------------------11-----------1-------11--1------1--------------1----------------------------------------------------------------------11-----------1----------------1--------------------1 ----2---11--07---1-1-1------1---------1-----113-------1----2-1--------------1----------------1--111--1-------222-1------1---4112-1---1-31--2-114112---3-11-11-31--3-121---11111---------14-11-112-112--
 ction (DUF1539)                            **                                          *                                                                                           *   *                  **            *******                        *                   *          **    *                *               *            *                             *                                                                *                    *                                                                                                                                *                       *               **         *           *          *   *  *  *             *           * **   *                     *                                *           *             *                                                                       **           *       **  *      *              *                                                                      **           *                *                    *     *   **  **   * * *      *         *     ***       *    * *              *                *  ***  *       *** *      *   **** *   * **  * ******   * ** ** **  * ***   *****         ** ** *** ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7668] PF09170            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1879:Domain of unknown fun  --------------111--------------1----------------------------1---1--- -------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-----------------------1-1---------------------------------------1------------11--------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1------------------------------1------------------------1------------------1-------------------------------111-----------------------------------------------------------------------------------------------1------1-------------1-----------------------------1--1111----1-------------------------------1------------- -1---1------111----1-----1-------1----1-------1--1-------------------1----------1----------1-----------------255411231211123422114-3-32312334-12122121421432222-111-22-1----22-----------124-1----1112-
 ction (DUF1879)                              ***              *                            *   *                                                                                               *                                                                                                                                                                        *                       * *                                       *            **                                **                                                                                                                                                                                                               *                   *                              *                        *                  *                               ***                                                                                               *      *             *                             *  ****    *                               *               *   *      ***    *     *       *    *       *  *                   *          *          *                 ********************* * ******** ***************** *** ** *    **           *** *    **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7669] PF00963            179                                                                                                                                                                                                                                                                                                               1                                                                                                         1         2                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
 Cohesin:Cohesin domain         ---------------1-------21------1-----1---11-1----31-2-----1--------- 111----------------------------------------1---------------------------------------------------------------1--------1----------11-1------------------1-1------------------------------1-1---------1-11-1----1-----11--------11------1-12---------------------1--------------------------------------------------------------1--------6------1----0-------1-9---1-----5--11---------1------------------------------------------------------------------1-------------------------------------------------------------------------------------------------21--------------------1-1-----11-115-4-----------3221222---------1--1-------1------------1-----------3-------------------1----------------------------------------------------1-----------------------------------------------------1--1-------------------------------------------------------------------------------------------11------------------------------------------1-1--------- 1-----3-------1-----1--1-1---------------------------------111----1--------1-----111---------1----------1---------------------------------------------------------1------------------------------1-1---
                                               *       **      *     *   ** *    ** *     *          ***                                        *                                                               *        *          ** *                  * *                              * *         * ** *    *     **        **      * **                     *                                                              *        *      *    *       * *   *     *  **         *                                                                  *                                                                                                 **                    * *     ** *** *           *******         *  *       *            *           *                   *                                                    *                                                     *  *                                                                                           **                                          * *          *     *       *     *  * *                                 ***    *        *     ***         *          *                                                         *                              * *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7670] PF09948            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2182:Predicted metal-bindi  ---------------------------1--11------------------------------------ -----1--------3----------------------------1---------11-------3---2---------------1--------1--------------1-------------------------------------11-----------------------------------------------------1----1-----------1--------------------------------------------------------------------------------------------------------------------------------1----2-----------1-----------1----------1-------------------------------13-----1--1---11-----11----1211-----------------------------------------------1---1111-222222-111122-111111132---2---121-----224-1--------1------------------------------------2-----1------------------------------------2-----------2------11-------------------------------------------1----------1-----1-------------------------------------------------1---1------------------------------------------------------------1-1--------------------------------------------------------------------------------- ------1-------1----1-1---------------111------------1---1---1--------------------------1--1----2-1---2---1--5-11-2--1-------13---1-2---31-----2-1---11----1----1---1-------231--22--2-------1-----2211-
 ng integral membrane protein                              *  **                                          *        *                            *         **       *   *               *        *              *                                     **                                                     *    *           *                                                                                                                                *    *           *           *          *                               **     *  *   **     **    ****                                               *   **** ****** ****** *********   *   ***     *** *        *                                    *     *                                    *           *      **                                           *          *     *                                                 *   *                                                            * *                                                                                        *       *    * *               ***            *   *   *                          *  *    * *   *   *  * ** *  *       **   * *   **     * *   **    *    *   *       ***  **  *       *     **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7671] PF11939            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3457:Protein of unknown fu  ---------------------------1----------------1----------------------- --1----------------------------------------------1-------1------1---1--------------------------------------------------------------------------------------------------1---1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--1--11-121---111-1------------------------------1-----11-----11111----------------1----------------------------------1--------1111---------1------12---12------1----1-1----1----------------112--------1----------1----11-1------------------------------111-1------------------------------1--------1-111--1111111111-1111111111111111111---1---11211111111111111-1111111--1-----------------------------111111-------------------1-1--1----------------------------------------1-11---------2--------------------------------------------------------- ------------11-1------1-21---------------------1--------1--11--------------1---1---------------------1-1-1-1----2-3----1--1-1--11----2----------2----------------1--112----1-1-------1-1----111--1-----
 nction (DUF3457)                                          *                *                          *                                              *       *      *   *                                                                                                  *   *                                                                                                                                                                                                            **  *  ** ***   *** *                              *     **     *****                *                                  *        ****         *      **   **      *    * *    *                ***        *          *    ** *                              *** *                              *        * ***  ********** *******************   *   ***************** *******  *                             ******                   * *  *                                        * **         *                                                                      ** *      * **                     *        *  **              *   *                     * * * *    * *    *  * *  **    *          *                *  ***    * *       * *    ***  *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7672] PF01716            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               1       1           
 MSP:Manganese-stabilising pro  ---------------------------1-1---------1--1-------------1----------- -----------------11-1-----11111------------------------------------------------------------------------111--1------------------------------------1111111111111111111111111111111111111----------------------------------------------------------------------------------------------------------------------------------------------------1------1---------------------------------------------------------------------------------------------------1-------------------------------------------------------------1------------------1---------------------------------------------------------------------------------------------------------------------------------111---------------------------------------------------------------11------------------------------------------------1--1-----111------------------------------------------------------------------------------------------------------------------------------------------- ----2----------111----1----------------------------1---1----------1---1--1-----1------------1------1-2-11---21---4-2----1------1-1-1-3311-1----1--1--------------1---2-------1-11118212225112-43121-1-1
 tein / photosystem II polypep                             * *         *  *             *                             ** *     *****                                                                        ***  *                                    *************************************                                                                                                                                                    *      *                                                                                                   *                                                             *                  *                                                                                                                                 ***                                                               **                                                *  *     ***                                                                                                                                                *          ***    *                            *   *          *   *  *     *            *      * * **   **   * *    *      * * * **** *    *  *              *   *       * ************** ***** * *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7673] PF09438            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2017:Domain of unknown fun  ----------------------------11------------------------1------------- ----111111111111211-11111111111111111124121121111111111121--112-3311111----------------------------1--------------------------1-----------1------3---------1-------1-----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-----------1------------------------------------------1-11-1112-11------1----------11-1--------11-------1------------------------------------------------------------------------1-1----------------------------------------------------------------------1------------------------------------1-1-------------1----------------------------------------1---------1-1--1------------1---1---------------121-------------------1---------------------------------------------------------------------------1-- --------21--11-1--1-11-3-1--------------------1-111--------1111----1----------------1------1------11---------11------1--11-1-1-11----------1-----1-1---1-----1--1-1--1-------1-11--1--11-111-----------
 ction (DUF2017)                                            **                        *                  *************** **************************************  *** *******                            *                          *           *      *         *       *     *                                                                                                                                                                                                                                                           *           *                                          * ** **** **      *          ** *        **       *                                                                        * *                                                                      *                                    * *             *                                        *         * *  *            *   *               ***                   *                                                                           *           **  ** *  * ** * *                    * ***        ****    *                *      *      **         **      *  ** * * **          *     * *   *     *  * *  *       * **  *  ** ***           
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7674] PF09435            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2015:Fungal protein of unk  ----------------------------2---------------------------1----------- ---------------------------------------------------------------------------------------1--1------------------------------------------------------1----------------------------1------------------------------1---------------1-----------111-1--1-1-1----------------------------------------------------------------------------------1111111-1---------1----------------------------------------11-------------------------------------------------1------------------------------------11-----------------------------------------------------------------------------------11111---------------------------------------------------1------------------------------------------1--1--------------------------------------------------2---1--------------------------1------------------------------------------------------------------------------------------------------------1-1------11-------1-------------------------------------------- --1---1--------1222-1111111221111-1111111113-111111112111111111111---11-1-112-2111112111111121111112131111-1--12112-1-11------11-------------------111--1--11-1--2-1--1---1--1-----1-----1---1111--1---
 nown function (DUF2015)                                    *                           *                                                                                                   *  *                                                      *                            *                              *               *           *** *  * * *                                                                                  ******* *         *                                        **                                                 *                                    **                                                                                   *****                                                   *                                          *  *                                                  *   *                          *                                                                                                            * *      **       *                                               *   *        **** ************* ********** *********************   ** * *** **************************** *  ***** * **      **                   ***  *  ** *  * *  *   *  *     *     *   ****  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7675] PF05745            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CRPA:Chlamydia 15 kDa cystein  ----------------------------1--------1----1--------1---------------1 -----------11----------------------------1---1-------211-2-----1----1-2---------2---------2---1--------------111111111-1111-----------1-----1----2-----1-----------------------------1----------1-1-11-------1--1-11-2--1------3---1-----------------------1---------1---------------------------------------------------11---111-1-----------1--1111----1----------1------------------111-----------------------------------1--------------1----------------1---------------------1-------1----------11-------------------1-----------------1------------------------1-------------------11----------------------------1-------------------------------------1-------------1--1---------------------1------------------------------1111---------------------------------11---1--------------------------------1------------------1--1--------111----------------------11----------------------------------1-------1----------1------------1------- -----1---1-1111-11--------1--2----1-----------22-1------1-----------------11------------1---1--------1--11--4112-1112----1-------1---------1---1---------4-----111-32------41-1-3---------11--1-1------
 e-rich outer membrane protein                              *        *    *        *               *            **                            *   *       *** *     *    * *         *         *   *              ********* ****           *     *    *     *                             *          * * **       *  * ** *  *      *   *                       *         *                                                   **   *** *           *  ****    *          *                  ***                                   *              *                *                     *       *          **                   *                 *                        *                   **                            *                                     *             *  *                     *                              ****                                 **   *                                *                  *  *        ***                      **                                  *       *          *            *             *   * **** **        *  *    *           ** *      *                 **            *   *        *  **  **** ****    *       *         *   *         *     *** **      ** * *         **  * *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7676] PF09954            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2188:Uncharacterized prote  ----------------------------1--------------------------------------- ------1-11--1-------------------------------------------------1--------------------1------------------11---1------------------1--1----------------11------------------121-----------------------1---------------1-1111-------1-2111111-1111111111111111111111------1-----------1--1---1------------------1--------------------------------------1--211-----1---1-------1-----------1---2----------1---------1------------------1---1------1-1----------1-------1---------1----1---------------------------------1-------1------1111-----1111----461----------1111--1-1---------------------11------1--1-----------1--------------------------------------1---1-----1-----------1------1------------------------------------------------1------1------------------------------------------------11--1--------------------------------------2--1---111112111-------------------------------------------------1------111-1-----111---111-1--1--------- ------------------1------------------------------11-------1111-------------------------1-----1---------1------11---1-----------1-1-------1-----1----1------1-----21----1----1-1-----1---1---1-------1--
 in conserved in bacteria (DUF                              *                                              * **  *                                                 *                    *                  **   *                  *  *                **                  ***                       *               * ****       * ******* **********************      *           *  *   *                  *                                      *  ***     *   *       *           *   *          *         *                  *   *      * *          *       *         *    *                                 *       *      ****     ****    ***          ****  * *                     **      *  *           *                                      *   *     *           *      *                                                *      *                                                **  *                                      *  *   *********                                                 *      *** *     ***   *** *  *                            *                              **       ****                         *     *         *      **   *           * *       *     *    *      *     **    *    * *     *   *   *       *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7677] PF10917            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                3       1                          
 DUF2708:Protein of unknown fu  ------------------------------1------------------------------------- --1-----------------------------1--------1--------------------------1----------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------1---1-----------------------------1------------------1------1---------------------------------1-------------------------------------------------------------------------------1-----------------------------1-------------------------------------1----------1----2---------------2-------------------------1-------------------------------------------------------------------------------------------------------1--------------------------11----11-----11-----------------------------------------1----2----------------------1-------------1-1-----11---------1-------------------------------------------- -2--1-----11-----2------1-1--1111----1--1-----1----11----1------------------1----------1----------------------211--2--------3--119-3-1-1----211--------1---1---1212433-423222-1-21----1---333----12----
 nction (DUF2708)                                             *                                        *                             *        *                          *                                                                                                                            **                                                                                                                               *   *                             *                  *      *                                 *                                                                               *                             *                                     *          *    *               *                         *                                                                                                       *                          **    **     **                                         *    *                      *             * *     **         *                                              *  *     **     *      * *  ****    *  *     *    **    *                  *          *                      ***  *        *  *** * * *    ***        *   *   ******* ****** * **    *   ***    **    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7678] PF11398            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2813:Protein of unknown fu  -------------------------------1-----1--------------------1--------- -------------------------------------------1-----------------------------------------------------------------------------------1---------------2------------1---------------------------------------------------1--------------------------------------------------------------------------------------------------------11---111----------------------1-----------11-------1----------1-----------1--------------------------11-----------1--------------1-------------------------------------------------------------1----1---------------------------------1--------------------------1-------------------------------------------------------1--111-----1-3------------1-------------------11111111111111111-111111111111111111111211--1111111111111111111111111--1111111111211---------1-------1111-1--------2-----------------------------1---------11111111111111---------------------------------------------1---------1----11------------ --111-----11---1-------------------1----1----1----1---------------------1--1-------1---1-----2--------1------1---1-------1-------------1----------1--1------------21111---1---1-----1--------------1--1
 nction (DUF2813)                                              *     *                    *                                                     *                                                                                   *               *            *                                                   *                                                                                                        **   ***                      *           **       *          *           *                          **           *              *                                                             *    *                                 *                          *                                                       *  ***     * *            *                   ***************** ************************  *************************  *************         *       **** *        *                             *         **************                                             *         *    **               ***     **   *                   *    *    *    *                     *  *       *   *     *        *      *   *       *             *          *  *            *****   *   *     *              *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7679] PF07227            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1                11 1        
 DUF1423:Protein of unknown fu  ---------------------------------------------1---------------------- -----------------11-1------------------------------------------------------------------------------------1---------------------------------------------------1---------------------------------------------1--------1-------1----------------------------------------1--------1-----------------22222222222--------------1-------------------------------------------------1----1--1-----------------------1-------------1-----------------------1--------------------------------------------------------1-----1--------------------------------------------------------------------------1-----------------1-1--------------------------------1-------------------------------------------------1-------------------------------------1---------------------------------------------------------------------------111111----------------------------------11-----------------------------11-------1--1------------------------------------------- --11----1------1-------------1111----------1-22----------1---------------1----------1--11--1---1-----1--11--21--2-1---1----1-----------1---12--21---------1---1---11--1---0---1-1-211-1114604-3611-2---
 nction (DUF1423)                                                            *                                        ** *                                                                                    *                                                   *                                             *        *       *                                        *        *                 ***********              *                                                 *    *  *                       *             *                       *                                                        *     *                                                                          *                 * *                                *                                                 *                                     *                                                                           ******                                  **                             **       *  *                                              **    *      *             ****          * **          *               *          *  **  *   *     *  **  **  * *   *    *           *   **  **         *   *   **  *   *   * * *** ******* **** *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7680] PF05643            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF799:Putative bacterial lip  ---------------------------------------------------1---------------- ----1-------------------------------------------------------1------1-----------------------1--------1---------------------------1------------------------------------11----------------------------------------------------------------------------------------------1----------------------1------------------------------------------------------11--------------------------------1------------------------------------------------------------1------111-----------------1------------------------------------------11111-1111111--111111-1-1-12----11--1111-1-1-1------11121111-------1-1-----------11-1-11--2222-12--11-1---------------------------11-------1--11-------1------------------11-----------2---1-11--111------------11111----------------11--1111--111111111111---------------1--111--------1---------------22221111-1111-111-------------------1--------------------------------------------------------------------------5--1 -----1-------1---1---------------1-------------1----1--1-11----------------------------------11----------1--3----------------------1--21---------------------------1---11---4---------------1--------1-
 oprotein (DUF799)                                                                 *                     *                                                       *      *                       *        *                           *                                    **                                                                                              *                      *                                                      **                                *                                                            *      ***                 *                                          ***** *******  ****** * * **    **  **** * * *      ********       * *           ** * **  **** **  ** *                           **       *  **       *                  **           *   * **  ***            *****                **  ****  ************               *  ***        *               ******** **** ***                   *                                                                          *  *      *       *   *               *             *    *  * **                                  **          *  *                      *  **                           *   **   *               *        * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7681] PF09149            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    532                                                                                                                                                                                            
 DUF1935:Domain of unknown fun  -------------------------------------------------------1-1-11------- ---------------22-------1------1------1--------------------------------------------------1-----------------------------------------------------1-----1--------------------------------------------1--1---1--------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------1--------11----------------------1-----------------------------------1-----------------------------------1-----------------------1--------------------------------------------------------------------------------------11--------------------------------------------------------------------------11---1-------------1------------------------1111---1--------------------------------------------------------------------------- -2------300----1--------------------------------------------------1---------1--1---------12----1---------1---2--1-------1-1---1----------------------------1------12-8-----1-31-------------1-111--1---
 ction (DUF1935)                                                                       * * **                       **       *      *      *                                                  *                                                     *     *                                            *  *   *              *                                                                                                                                                                                                                          *                                                            *        **                      *                                   *                                   *                       *                                                                                      **                                                                          **   *             *                        ****   *                                                                             *      ***    *                                                  *         *  *         **    *         *   *  *       * *   *                            *      ** *     * **             * ***  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7682] PF11272            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               1                   
 DUF3072:Protein of unknown fu  ------------------------------------------------------------------1- --1---11-------1-----1----------11113--1----1----11----1----11--1-12-----------------1------------------1----------------------------1---------1------------------1-------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------2-------1-----2--------1--1----------1----------1-12---11-------------1-11111111-1-----2----1-------1-------------------11--1--------------------------------1----------------------2---------1--------1-----------------1------------1--------1-----------------11-1-------------------------1----------1------------------1--------------------1----------------------------1---1-111-------------------------------------------------------------------------------------1------2-------1----------------------------1-2-2------------------------------------------------------------------1-- -1---1-----1-1---11-21----1----1---1----2-----12-1--1----1-1-1----------1-----1--------------------2-1-----14-31----1-2-1-3--1--1-------1--1---111-------11-1-----21-------1-2---3-7----11-1------221--
 nction (DUF3072)                                                                                 *    *   **       *     *          *****  *    *    **    *    **  * **                 *                  *                            *         *                  *                                                                         *                                                                                                    *       *     *        *  *          *          * **   **             * ******** *     *    *       *                   **  *                                *                      *         *        *                 *            *        *                 ** *                         *          *                  *                    *                            *   * ***                                                                                     *      *       *                            * * *                                                                  *    *   *     * *   ** **    *    *   *    *     ** *  *    * * *          *     *                    * *     ** **    * * * *  *  *       *  *   ***       ** *     **       * *   * *    ** *      ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7683] PF08633            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Rox3:Rox3 mediator complex su  -------------------------------------------------------------------- 1-------------------------------------------------------------------------------------------------------------------------------------------------------------1-------111------------------------11111--1---1---1-----1--1-----------------------------------------------11----------------------------------------------------------1------------------------------------------------------------------------------------------------------------------1----------------------1----------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1------------------------------------------------------------------------------------ --------1------312121111212213222111112112222212122221112111112221111-11-121112211112-211-4-1------1-2-----1321--1-1----------1---------12------3--------1-311--2---232---1-----12--------21-1-1---211-
 bunit                                                                                               *                                                                                                                                                             *       ***                        *****  *   *   *     *  *                                               **                                                          *                                                                                                                  *                      *                                                                                                                *                                                                                                                                                                                                                                                           * *                                                                                             *      ****************************************************** ** ************ *** * *      * *     ****  * *          *         **      *        * ***  *   ***   *     **        ** * *   *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7684] PF10185            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Mesd:Chaperone for wingless s  -------------------------------------------------------------------- --1----------------------------------------1----------------------------------------------2---------1----------------1--------------------------------------------------------1---------1--------------------1------------1----------------------------1---------------------------------------------------1111111111111-------------------------------------1----------------------------------------------1-------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------111---------------------------1----------------------------------------------------------------------------------------------------------1-1-----------------------------------------111-11---1------------------1--------------11111---11-------------------------------------------------------------------------- 11----1---1--------------------1--------------11---------1------1--------1------------------------1--1-----12-2-122212332211122213-21223112222211221-221-511122131121121132211----1------1--3-12--2-111
 ignalling and trafficking of                                                                          *                                        *                                              *         *                *                                                        *         *                    *            *                            *                                                   *************                                     *                                              *                                                                                                 *                                                                                                                ***                           *                                                                                                          * *                                         *** **   *                  *              *****   **                                                                           **    *   *                    *              **         *      *        *                        *  *     ** * ****************** ***************** *** *********************    *      *  * **  * ***
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7685] PF06037            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF922:Bacterial protein of u  -------------------------------------------------------------------- -----------1-------------------1---------1-1-----------------1------11-------------1------------------11-1-----------------------------111------1--1---------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1----------------1-1-----------1---------122222222223---------23--222222222222----1---------1-------------1----------------------------------1------1-----------------------------1--1--------------------------------1---------------111-----------------------------------------11----1---------1----------------------------11------------------------------------11--------------------------------------1-------------1----2-----------------------------------11------------------------------------1--------------------------------------------------------------------- ------1----------11----211-------1------------1----------------1---------------2------1---6--1-11-1--5----1-12-1-1-------11--1-214-1-31------11----1----------1-12-1232-1-2-------------1-1131---1---2-
 nknown function (DUF922)                                                                                       *                   *         * *                 *      **             *                  ** *                             ***      *  *               *    *                                                                                                                                                            *                             *                * *           *         ************         **  ************    *         *             *                                  *      *                             *  *                                *               ***                                         **    *         *                            **                                    **                                      *             *    *                                   **                                    *                                                                            *          **    ***       *            *                *               *      *   *  * ** *  *    * ** * *       **  * *** * **      **    *          * ** **** * *             * ****   *   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7686] PF11027            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1                                                                          
 DUF2615:Protein of unknown fu  -------------------------------------------------------------------- -------------------------------------1----------------------------------------------------------------------------------------------------1-------1--------------------------------------------1-111---1-----------------------------------------------1--------------------------------------11-11--------------------------------------------------------------------------------------------------------------------------1--1---------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------1----------1-11-1----------------------1-----------------------------------------------------------------------------1---1-----------------1-----------------------------------------------------1--------------------------------3-------------1-11------------------------------------------------------------------- ------1----2----11-----------1---1-1----------1-------------------------11-----------1----1-11----1----2---22142-332311211110311-2-1-11311111-11-1-2-121211313114-512214231112---2----2---132-2-3---23-
 nction (DUF2615)                                                                                                                         *                                                                                                    *       *                                            * ***   *                                               *                                      ** **                                                                                                                          *  *                                                                                                                           *                                                               *          * ** *                      *                                                                             *   *                 *                                                     *                                *             * **                                                                          *    *    **           *   * *          *                         **           *    * **    *    *   ***** *************** * * ******** ** * * ************ ************   *    *   *** * *   ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7687] PF04915            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DltD_N:DltD N-terminal region  -------------------------------------------------------------------- -----------------------------------------11----------------------------------------------------------------------------------------------------------------------------1------------------------12222222312222221-1111223---1---211111--1111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111----------------1------------1---11-------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------1---------------------------------------1--------------------------------------------------------------------1------------------------------------------------------------------------------1--------------------------------------------------------1----------------------------------------------------------------1------------------------------------2----------------------------------------- --------------1-------------------------------3------------------------------2-------1---------------2---1-----------------------1--------------------11---------1-1--1-----1-1-----------12------1----
                                                                                                                                              **                                                                                                                            *                        ***************** *******   *   ******  **************************************************************** *************************                *            *   **                                                                                                             *                                                           *                                       *                                                                    *                                                                              *                                                        *                                                                *                                    *                                                        *                               *                              *       *               *   *                       *                    **         * *  *     * *           **      *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7688] PF05612            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF781:Mouse protein of unkno  -------------------------------------------------------------------- ----------------------------------------------------------------------------------------11--------------1----------------------------1----1--------------------1------1-1--------1------------------------------1---------------------1----------------------1--------------1---------------------------------------------------------11111--1-1----------1---------------------1--------------------------------------------------------------------------------------------------------1-----------------------------------------------------------1------------------------------------------1------------------------------------------1-------11--------1----1----------1--------------------------------------------------------------------------------------------------------------11-1-------------1-----1-----------------------------------------------------------------------11--1----------------1----------------------1----------- 1---31-----1------------1-1-1------------1----------1-------------1---1----1---------1-1--1---11-----1-1-1---1-223-232112223632223-1-1121211212241123522124321112-41112------31----------11-1---1----1-
 wn function (DUF781)                                                                                                                                                                        **              *                            *    *                    *      * *        *                              *                     *                      *              *                                                         *****  * *          *                     *                                                                                                        *                                                           *                                          *                                          *       **        *    *          *                                                                                                              ** *             *     *                                                                       **  *                *                      *            *   **     *            * * *            *          *             *   *    *         * *  *   **     * * *   * *** *************** * **************************** *****      **          ** *   *    * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7689] PF10863            179                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2702:Protein of unknown fu  -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------1-------------------------------------------11-----------------------------------------------1-----------11--1------1-1---------11111111111111------------------------------------------------------------------1---------------------------------1-----------------------------------------------------------------1-----------1-------------------------------------------------------------------------------------------------------------------------------1---------------------1--------------------------------------------------1----------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------4-----------------------------------1-------------------- -----1-----------111---1-1--------------------11--3-2-12-2----112111111111111311111112-----1---------3-1-1---1-2-2--223113214212-5-2111111132112---111221221211--1112-111-111---------------1---3113---
 nction (DUF2702)                                                                                                                                                                                             *                                           **                                               *           **  *      * *         **************                                                                  *                                 *                                                                 *           *                                                                                                                               *                     *                                                  *          *                                                                                                                                                                        *                                                   *                                   *                          *           ***   * *                    **  * * ** *    ************************     *         * * *   * * *  ************ * *************   ************  **** *** ***               *   ****   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7690] PF09512            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 ThiW:Thiamine-precursor trans  11-----1----------2---1----1--------1-----------------------2---2--- --1-1-1--------------1----------1-----1---------1--------------------2------------1----------------------1------------------------------11111--2-1-----------1-1-----------------------1--------------------------------1---1111---------11111111111111111111-1-11-1-----11111--11----111-------11111111111------------------------11-11111111111---------1-111-1-----1---1-1221------1-----------1------1-11-------------------------------------1---------------------------------11-------------------------------------1-----------------------3-------------------------------------1-------------------------1-------------------------------------1------1-----21111-1---------------------------------------------------------------------------------------------------------------------1----------------------------------1-1------121-------------------------------------------------------------------------------------------------- ----------1---------1------------------1-------1-------------------------------1---------1-1----1-1-----------6132---1---------1-1-----2--------------------11-1---------1-------1------------121---21-
 porter protein (ThiW)          **     *          *   *    *        *                       *   *      * * *              *          *     *         *                    *            *                      *                              *****  * *           * *                       *                                *   ****         ******************** * ** *     *****  **    ***       ***********                        ** ***********         * *** *     *   * ****      *           *      * **                                     *                                 **                                     *                       *                                     *                         *                                     *      *     ***** *                                                                                                                     *                                  * *      ***                                                                                                             *         *                  *       *                               *         * *    * *           ****   *         * *     *                    ** *         *       *            ***   ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7691] PF06953            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 ArsD:Arsenical resistance ope  11---1----------2--------1111-1---1-----1----1----1----------------- ---------------------1----------1----1-1------1--------------------------------------1----31----1---------------------------111---2111-1----111----------------------1---------------------------------1----1---------------1--1211111------------------1111--1---------2----------2-2---------------------------------------------21-1111111---1--------1--11---1111--11-------------1-----------------1-1-1-------------------------------------1--------------------------1-1---------------------------------------------------111--------1-------1--1---1-1-1--2---1---1----------112---1---1-1---1-------1--------11---------------------1-----111---------1111---111211-12------1--------------------------------------1------22---1--3------1-1----------------1---------------------------------------------------------------------3-1-------------11-----1-----1------------------11------------------------1-------------------------11 1-------1--1-----------------1----1------------2---------------------------------11-1---------------------------------------------------------------1------------1-41----1-1-------------1----1---1--1-
 ron trans-acting repressor Ar  **   *          *        **** *   *     *    *    *                                       *          *    * *      *                                      *    **    *                           ***   **** *    ***                      *                                 *    *               *  *******                  ****  *         *          * *                                             ** *******   *        *  **   ****  **             *                 * * *                                     *                          * *                                                   ***        *       *  *   * * *  *   *   *          ***   *   * *   *       *        **                     *     ***         ****   ****** **      *                                      *      **   *  *      * *                *                                                                     * *             **     *     *                  **                        *                         ** *       *  *                 *    *            *                                 ** *                                                               *            * **    * *             *    *   *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7692] PF11591            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 2Fe-2S_Ferredox:Ferredoxin ch  -1------------------------------------------------------------------ ---1---1------23211-1----111111------1---1--11-1--1--1--1------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------111-2-------------122-----2---------------11------------------------------------------3211-----113212--1111113---3-1----1--1----------1------1-----------1---------1-1-----1-1------1-11-3------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------1-1-------------------------------1--------------------------1--------1-1-------------------------------------------------------------------------- ----------12-----2-----1-1-----1----1----1-1111-11--112----1-2----------------------------4------1---1---1--3-11-11-1----1-12--3---2-12---1----11----11-------41-----21-1-1-----222--2-2--121-------21-
 loroplastic transit peptide     *                                                                      *   *      ***** *    ******      *   *  ** *  *  *  *            *     *                                                                                                                                                                                                                                                                                                                              *                   *** *             ***     *               **                                          ****     ******  *******   * *    *  *          *      *           *         * *     * *      * ** *                                                                                                                              *                                         * *                               *                          *        * *                                                                                     **     *     * *     *    *    * **** **  ***    * *                            *      *   *   *  * ** ** *    * **  *   * **   *    **    **       **     ** * *     ***  * *  ***       ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7693] PF11847            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3367:Domain of unknown fun  -1---2---------1----1---2------------------------112---------------- --1--1111111-111111-11112311111122221111-222-1---------1----131----1-11----------------------------------------------------------------1---1---1------------------------------------------1------------------------------------1--------------------------------------1-----1--1---------------------------------------------------1-------------------------------11-1-----------------11-------------------------------22-22-1-12--1---111111-----1----------------------1--1-----------------------------------------1-------------1--------11-----11-----------------------------------1-1---11-------1------11--1-1-------1111----------------11-----------------------------------------------1-----1-11-----------------------111-----------------------------1-----------------------------------------------------------------------1---------------------------1---1---------------------------1----------------------------------------- ------1-11--11---1--1--11-1-------------------1------1-2-------------------------------------1-1---1--------11------1--1---------------------------------11------2----1------1---2----1--123---2--11-1-
 ction (DUF3367)                 *   *         *    *   *                        ***                   *  ******* ****** ******************** *** *         *    ***    * **                                                                *   *   *                                          *                                    *                                      *     *  *                                                   *                               ** *                 **                               ** ** * **  *   ******     *                      *  *                                         *             *        **     **                                   * *   **       *      **  *