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Ranking of HM:PFM:REP : from 7701 to 7800

                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7701] PF07820            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 TraC:TraC-like protein         -----------------------------111------------------------------------ ---1----111----11--------1----------1-----------------------------------------------------1------------------------------------------------1----1--1------------------1-1--------------1-1---------------------------------------11-1----1--------------1------------------------------------------------------------------------------------------11---------------------------------------1----1--11---121---1---1-111-11--11-1111-222522221-21-2--1-1-------------------1------------------------------------11-----1---1---1-------2112------1------------------11------------------1-------------------------------------------------------------1------------------------------------------------------------------------------13-------------------------------------------------------1---1------------------------------------1-----------------------------------------1----------------------------------------------------------------- --------11-2---1----12-1-1-----------1111------111--1-----1---------------------------1------1-------1-----1---1311--1--1112111111-1-128-11111111-1--11111111-------1-----------1--21-----------111----
                                                             ***                                        *    ***    **        *          *                                                     *                                                *    *  *                  * *              * *                                       ** *    *              *                                                                                          **                                       *    *  **   ***   *   * *** **  ** **** ********* ** *  * *                   *                                    **     *   *   *       ****      *                  **                  *                                                             *                                                                              **                                                       *   *                                    *                                         *                                                                          ** *   *    ** * *           ****      ***  *     *                           *      *       *     *   ****  *  ********** * *** ******** *  ********       *           *  **           ***    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7702] PF09902            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2129:Uncharacterized prote  ---------------------------------1---------------------------------- ----------------------------------------------------------------------------------------------------1---1---------------------------------------------------------------------111-1--1---------111111111211111111111111-1111111211111111-11111111111111111112211111111111111111121-111111111111111111111111111111111-11111111111111------------------------1---------2------------2---1----1-----------------------------------------------------------------------------------------------------1-1--1-----------------------------------------------------------------------1-------------------------------------------------------1------------------------------------------------1----------------------------------------------1-----------------------------------------------------------1----------------------------------------1------------------------1--------------------------1-----------1-------------------------11------------ -1--------------------------------------------1------------1--1------1--------1-------------------------2-----1----2--------1-------------------------------1--------1-----------------1--1------------
 in conserved in bacteria (DUF                                   *                                                                                                                                       *   *                                                                     *** *  *         ************************ **************** ***************************************** ********************************* **************                        *         *            *   *    *                                                                                                     * *  *                                                                       *                                                       *                                                *                                              *                                                           *                                        *                        *                          *           *                         **              *                                            *            *  *      *        *                         *     *    *        *                               *        *                 *  *            
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7703] PF06304            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1048:Protein of unknown fu  -----------------------------------111-----1-----------1-11--------- ---------------------------------------------1------12----------1-------------------------1-------------------------------------------------------------------------------1-------1----------1---11111121-211111-311-11-1----1--111111-2------------------1-1----------------------222---------------------------------------------1-1-1111121-121-33---------------3------------------------------------1----1------------1---------------1-------------------1----------------------------------1---------------------1111111-11-11111111111111111----11------1-----------------------------1----------------------------1------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------1--1--------------------------------1--------------------------1-1--111---------------------------------------------------------------- --11------------1----1---------------121111-----1111-----------------------1----------------11-----1-----1----1222311-1---------------1---1-------111---1------------111-1---2-----------3---------1---
 nction (DUF1048)                                                  ***     *           * **                                                       *      **          *                         *                                                                               *       *          *   ******** ****** *** ** *    *  ****** *                  * *                      ***                                             * * ******* *** **               *                                    *    *            *               *                   *                                  *                     ******* ** *****************    **      *                             *                            *                  *                                                                                                                                                             *  *                                *                          * *  ***                                                                   **            *    *               ******     ****                       *                **     *     *    ******* *               *   *       ***   *            *** *   *           *         *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7704] PF07073            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 ROF:Modulator of Rho-dependen  --------------------------------------1-------------11-------------- 11------------------------------------------------------------------------------------------------------1------------------------------------------------------------1-----------------------1----------------------1-------------------1----------------------------------------------------------------------------------------------1111-21-1-----------------------------------------------1---------------------------------------------1----------------------------------------------------------------------------------------------------1--------------------1--1---------11---------------11----------------------------2---------------11-1----1-11-11111111111111121-2---11-1------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111-----------1--------------------------------111-11-1-1----------------------1111111111----------------------11-------------------------------------------------- -2-----------------------------------1-1-11----------1------------------1----------------------------2---------1--1----------------------1-------------------------------------------------12--1-1--1--
 t transcription termination (                                        *             **               **                                                                                                      *                                                            *                       *                      *                   *                                                                                              **** ** *                                               *                                             *                                                                                                    *                    *  *         **               **                            *               ** *    * ** ***************** *   ** *      ***************** **************************************************** ************           *                                *** ** * *                      **********                      **                                                    *                                   * * **          *                  *                            *         *  *                      *                                                 **  * *  *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7705] PF09746            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Membralin:Tumour-associated p  ------------------------------------------1---1-----------1--------- ---------------------------------------------------------------------------------------------------11------------------------------------------------------------------------------------------------1------1---------1-1----1---------------------------------1--1-----------1----1----------------------------------------------1---1--------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------1-----------------------------1----------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------11111111------------1-1-----------------------------------1--------------------------------1----- 1---2-------11-----------------------------1----------------1-------1-------1--3-11-1----12------------212-2-1321112111--112331213-2-224-1113-11--11--11-2111-112133415122712531---------1233-22112----
 rotein                                                                   *   *           *                                                                                                             **                                                                                                *      *         * *    *                                 *  *           *    *                                              *   *                                            *                                                                                                                                                                           *                            *                             *                                                    *                                                                                                                                                                  ********            * *                                   *                                *      *   *       **                             *                *       *       *  * ** *    **            *** * **********  ********* * *** **** **  **  ** **** ******************         **** *****    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7706] PF02924            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 HDPD:Bacteriophage lambda hea  -------------------------------------------1------------------------ ------1----------------------------------------1-11-----------------1---------------------------------------1--------------------1----1--------1---------------------------------------1------------------------------------1-----------------------------------11---------11----------------------------------------------------------------1---1----------------------------------1---11--21-2-------------------------41-11----1-----1---------1--------------------------1---------------------------2-45-----------1----------------------2-------------1--1-----------------------------1------12----------------1-----------------------------------------------------------------1--------------434-21-1--5114-13232333111-1----------------1----1--1-13-1111-----------------------------3-------------------------------1---------------------------------1-----1--------------1--------------------------------------------------------- -----11-1--1-----21----11------------------2---------3---111--------1--1------------------11-------------1----1--11---1---1----1-1-1---------------------------1-1-1---1-----2--11-1---2---1-1----1112-
 d decoration protein D                                                    *                               *                                        * **                 *                                       *                    *    *        *                                       *                                    *                                   **         **                                                                *   *                                  *   **  ** *                         ** **    *     *         *                          *                           * **           *                      *             *  *                             *      **                *                                                                 *              *** ** *  **** *********** *                *    *  * ** ****                             *                               *                                 *     *              *                                                               ** *  *     **    **                  *         *   ***        *  *                  **             *    *  **   *   *    * * *                           * * *   *     *  ** *   *   * *    **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7707] PF11748            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3306:Protein of unknown fu  -------------------------------------------------------------------- 1--------------11-------------------------------------------------------1-----------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1-1-----------------111111111-------------1------11-----122-------------1--------------------------------------1111------------------------12111111111-11-1111-11----------------111----2-------------------------------------------------------1----------11111-1111111111111----1----------------------------------------------1-----------------------------------------------------------11--------------------------------1-----111--------------12211111111111--------------------------------------------------------------1----------- -1--1-1-11--------------1----1---11--222111----1------1--2-2-2-1-----11-----1------111-----1-11------21--3--42--1--1-1-1-----1----------1-------2------------1--1--2------2--1--113-11-2-1---1-1--12-1-
 nction (DUF3306)                                                                                    *              **                                                       *                                                                                               *                                                                                                                                                                                                                         *  * *                 *********             *      **     ***             *                                      ****                        *********** ** **** **                ***    *                                                       *          ***** *************    *                                              *                                                           **                                *     ***              **************                                                              *             *  * * **              *    *   **  ******    *      *  * * * *     **     *      ***     * **      **  *  **  *  * * *     *          *       *            *  *  *      *  *  *** ** * *   * *  ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7708] PF10742            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2555:Protein of unknown fu  -------------------------------------------------------------------- ---------------1112-1-----11111------------------------------------------------------------------------------------------------------------------3111111111111111111111111111-11112-11------------------1-------2--------1-------------------------------1-------------------------------------------------------------------1---------1111-1-------------------------------------------11------------------------------------1--------1--1---------1-------------------------------1------------------------------------------------21-------------------------1----------------------------1----------------1---------------------------------------1----11--------11-1111-1--111-------------------1-------------------------------------------------------------------------------------------------------------------------2222-1--2----1----------------------------------------------------------------------------------------------------- 2---------------1-------------11---1----------31-------1-----------------1-----------------111-----------------451221-11--113-1316-1-3121111--11--11--1-------1---211-2-----1---1----3--1-1----------1-
 nction (DUF2555)                                                                                                   **** *     *****                                                                                                                  **************************** ***** **                  *       *        *                               *                                                                   *         **** *                                           **                                    *        *  *         *                               *                                                **                         *                            *                *                                       *    **        ** **** *  ***                   *                                                                                                                         **** *  *    *                                                                                                      *               *             **   *          **       *                 *                 ***                 ****** **  *** **** * *******  **  **  *       *   *** *     *   *    *  * *          * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7709] PF02159            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Oest_recep:Oestrogen receptor  -------------------------------------------------------------------- -------------------------1-------------------------1-1-----------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1-----------------------------------------------------------------------1----------------------------1---------------------------------------------------1----------------1111111-------------------------------1-----------------------------------------------------------1---------------------------1------------1-----------------------------------------------1--------------------------------------------1---------1--------------------------------------------------------- ---------------11---21-2---1-----2---232211211-3111--11----1-------------1-1-----11-1-----221-11---112---1----13122211111112511519-1-4222112111121111221-3121131-1--14----1111-------1-------11--------
                                                                                                                              *                         * *                                                                       *                                                                                                        *                                                                                                                                                                                                               *      *                                                                       *                            *                                                   *                *******                               *                                                           *                           *            *                                               *                                            *         *                                                                         **   ** *   *     *   ********* ****  **    *             * *     ** *     *** **   ***   *    ******************** * ******************* ******* *  **    ****       *       **        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7710] PF12064            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1     1                                                               
 DUF3544:Domain of unknown fun  -------------------------------------------------------------------- ---------------------------------1-1-------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------1---------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1-2-1-11---2-2-----11-------------1---1-1-------1----------------1----1-11-----------1--11-1-------1-----2734241133311742515-315201111111111112-112423411111-1-221---2-----1111----4--1-1---2-1--
 ction (DUF3544)                                                                                                                      * *                                                                                                 *                                                                                                                                                                                                                                                                                                                                                                                        *                               *                                                                                                         *                                                                                                                                                                                                                                                                                 * * * **   * *     **             *   * *       *                *    * **           *  ** *       *     ******************* ****************** ************ * ***   *     ****    *  * *   * *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 0002000001200001001230016001234000120000000100000010000000010000000000000120010100000C0101000001001000000000000123450000123020000100000011000100010123400101123456700010000123456789AB1000100001001234012345678900010001020100000012300000123456789ABCD001000000010000001010100000001201210120010123456789A0123456789ABC00101201200000001234567890001001200000000000100000001010000000000101000000001000012340100120001000000100000000010010012000000500001230010123456700100000020000120001000100000001001000000000000000123000123010101234000000100001000000000010000101100010123400001000000000200012200100000001010010000010123400001234562000001000000000000012300001230000000000000001234000000000123456789ABCDEFGHIJKLMNOPQRS0012010000123456789A0123400100120000012345678010000012340123000000120000012300100123450000000234001200123001200123456701011012340000101001230120123000001010100100000000010001001010001200000000100000100000000 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7711] PF09926            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2158:Uncharacterized small  -------------------------------------------------------------------- ---------------------------------1-1-----1-------------------------------------1------1------1---------------------------------------------------1------------------------------------------------------1--------------------1------------------------------------------------------------------------------------------11----------------------------------1-----------------------------------211---1-11-11---------------------1---1----------12---------------------------------------------------------------------1111111-11-11211111-1112----------------------------1------------------------11---------------1------------------------------13--------1-----------1--------------------12---2-11111-1-11--1111121111-1-11--1-1------2211121212111112-1-111-1-----------1--------------------1---------1----11--2-----1--------------------------------------------------------------11---------------------------------------------------- -------1-------11----211-11-11-----111-1111-1-1-----1----11---1-1-------1-----------------1-1-------------1-2--21--1--------1--1-1------------1----1-1--1------11--1-1-------------1----2---1--1------1
  protein (DUF2158)                                                                                                                   * *     *                                     *      *      *                                                   *                                                      *                    *                                                                                          **                                  *                                   ***   * ** **                     *   *          **                                                                     ******* ** ******** ****                            *                        **               *                              **        *           *                    **   * ***** * **  ********** * **  * *      **************** * *** *           *                    *         *    **  *     *                                                              **                                                            *       **    *** ** **     *** **** * *     *    **   * *       *                 * *             * *  **  *        *  * *            *    * *  *      **  * *             *    *   *  *      *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7712] PF11747            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
 RebB:Killing trait             -------------------------------------------------------------------- -------------------------------------------------------------1----1---------------------------------------------------------------------------------1----------------------------------------1------------------------------------------------------------------------------1-------------------------------------------------------------------1-------------------------------------11-------------------1-------------------1-----------------4---1---------3--------------8-----------------------------------------4----481111--1111111-4--------------------11-------7---------------0-------------1-1--------1---------1---------1-----------------1----------5-----------1-------------------1--------------------------------1------------------------------------------------------------------------------------------2-3-311--------------------9----------1--661111111---------------------------------------------------------------- ------1---------11---------21---1-21-111-------1---1-2--1--212---1--------------1----------11-------1--2----11------------------------1------------------1-1---------1-----2-------------12211-1-1-1---
                                                                                                                                                                  *    *                                                                                 *                                        *                                                                              *                                                                   *                                     **                   *                   *                 *   *         *              *                                         *    ******  ******* *                    **       *               *             * *        *         *         *                 *          *           *                   *                                *                                                                                          * * ***                    *          *  *********                                                                       *         **         **   * ** ***       *   * *  *  ***   *              *          **       *  *    **                        *                  * *         *     *             ***** * * *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7713] PF10504            178                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2452:Protein of unknown fu  -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------121---1-------------1111-----------1------------------------------------1----------------------------------1----------------------------------------------------1---1-------------------------------------------------------------1-111-1-111---1-------------1---------------------------------11-----------------------------------------1----------------------------------------------1-1-----------------------------------11----------------1-----------1---------------1-1---1-------------------------------1--------------------------1---------------------1----1----------1---------1----------------------------------------1------------------------------------11-------------------------------------------------------------------------111111111---22------------------11----------1------1-------------------------1---------- ------4-1--111--------1----11------------------1-----------1-2--------------------------------------1------11-221212311311121112-3-2-41321121122-1114111-1121-111-1311-1111-121----------111311-11---1-
 nction (DUF2452)                                                                                                                                                                                       ***   *             ****           *                                    *                                  *                                                    *   *                                                             * *** * ***   *             *                                 **                                         *                                              * *                                   **                *           *               * *   *                               *                          *                     *    *          *         *                                        *                                    **                                                                         *********   **                  **          *      *                         *                 * *  ***        *    **                  *           * *                                      *      ** ****************** * * *********** ******* **** *** **** **** ***          ****** **   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7714] PF09840            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2067:Uncharacterized prote  111211-3-1------2111212------------11121321---1-1----11121113--11-11 --1------------------------------------------------------------1---1------------1---------1---------------------------------1-----11------1-------1--12---------1---1-11---11----1--1----1---------------------------1--------------1---1-----------------------------------------------------------------------------------------1------------------------1-1----------------------1----------------------------------------------------------------------11-------------------------------------------------------------------11----1------------1-------------1------------------------11-----------------------------1--------------------------------2-----------------------1-------1-------------111-111---1---111---111-----------2---------------------11111-----------1-------------------2-----------------------------------------1-------------------------------------------1----22---------------------------1---------------------- -----1--21-------1-------1-----------11-111-------11-1------1------------1----11-------------1-11----2-----------------1----------------1--------11---1----1----------2-2--11--2---1-----1--4----1-4211
 in conserved in archaea (DUF2  ****** * *      *******            ********   * *    ********  ** **   *                                                            *   *            *         *                                 *     **      *       *  **         *   * **   **    *  *    *                           *              *   *                                                                                         *                        * *                      *                                                                      **                                                                   **    *            *             *                        **                             *                                *                       *       *             *** ***   *   ***   ***           *                     *****           *                   *                                         *                                           *    **                           *                            *  **       *       *           ** ***       ** *      *            *    **             * **    *                 *                *        **   *    *          * *  **  *   *     *  *    * ****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7715] PF07566            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1543:Domain of Unknown Fun  --1---------------------------------------------------------------1- -------------------------1------------1-----------------------------------------------------------------11--1--------------------------1--------------------222232--------222222222221----------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------111-----------------------------------------------1-2------------------------------------------2------------------1----------------------1---------------------------1-1-----2222222-------------1----------------11-1-----------------1--1--1---------2----2-2--------------11--------1----------22------------------1-----------------12-111-----------------------2----------------------------------------------22222-2-11-------212-2222----22-2-2--2-------------------1---------------------------1-----------------------------------1----- ------1------------1---1-1-111-------1-1---------1-----------1----------1-----------------------------1-------111------1-2-----1------2------------1--------11----1--2--------1-1--------1--12-------1-
 ction (DUF1543)                  *                                                               *                           *            *                                                                 **  *                          *                    ******        ************                *                                                                                                                                                                                *        ***                                               * *                                          *                  *                      *                           * *     *******             *                ** *                 *  *  *         *    * *              **        *          **                  *                 ** ***                       *                                              ***** * **       *** ****    ** * *  *                   *                           *                                   *            *            *   * * ***       * *         *           *          *                             *       ***      * *     *      *            *        **    *  *        * *        *  **       * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7716] PF01986            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF123:Domain of unknown func  --111-1-------1111111111111111-111111111111111111-11111111111--111-- ---------------1---------------------------------11-------------------------------------------------11-----1----------------1111111111111111------1----------------------------------------11--11-----------------------1-----------------------------------1---------------------------------------------1-------------------------------------1----------------1-------11--------------------------1--1-11------------------------------------------------------------1------1--------------------------------------------------------------------------------1-----------------------------------------------------------------------------1-----------------------------------1----111---------------------------------------------------1-111111-1111111--------------------------111------1-----------------------------------------------------------11-111-111-------------1-----1-------------------------------------------11111111111--1 ------1----------------1--1--1---1111-1--11-------1---1-----1-------------11--------------1---1-----1----1----1-----------1----2-2-1----1-111---------------1------1----------------------11---1----21-
 tion DUF123                      *** *       **************** ****************** ***********  ***                  *                                 **                                                 **     *                ****************      *                                        **  **                       *                                   *                                             *                                     *                *       **                          *  * **                                                            *      *                                                                                *                                                                             *                                   *    ***                                                   * ****** *******                          ***      *                                                           ** *** ***             *     *                                           ***********  *       *                *  *  *   **** *  **       *   *     *             **              *   *     *    *    *           *    * * *    * ***               *      *                      **   *    ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7717] PF09933            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2165:Predicted small integ  -----1-------------------------------------1------------------------ -1-------------------1-----------------1--1---------1-1---------211-1----------------------1---------------------------------1-----------------1----------------------------------------------2---------------------------------1111121-----------------------------------------1---------------------------------------11----111-----------1--------------------------------------------------------------------------1---1--1-2-1---------------2----1-----11-11111111----1--------------------------------------------11111---------1111-11----------1--1------1--2-----1------11-----------------------------------1-------3-11------------------------------------------------------1-------------1111112-11-111111211111111111------11-----------------211-111----11111111111---1111111111-11-1----------------------------1---21--1-1--------1111---------------------------------------------1-----------------------------------------11-- ----1-----1-----11--------------------1-----1--1---------1--------------------------------1-1-11--------------2------------------------------1-----------------------1----2-----1-----1---------1-2----
 ral membrane protein (DUF2165       *                                     *                          *                   *                 *  *         * *         *** *                      *                                 *                 *                                              *                                 *******                                         *                                       **    ***           *                                                                          *   *  * * *               *    *     ** ********    *                                            *****         **** **          *  *      *  *     *      **                                   *       * **                                                      *             ******* ** ******************      **                 *** ***    ***********   ********** ** *                            *   **  * *        ****                                             *                                         **       *     *     **                    *     *  *         *                                * * **              *                              *                       *    *     *     *         * *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7718] PF09557            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2382:Domain of unknown fun  ------1----------------------------1----------1--------------------- --3-11-1---11-----------------------1-------4--4----1--21------2-1--111-----------------------------1--------------------------------------------1233----------------2344-------------223----------------1-----------1--------1---------1----------------1-------------1-----------------------------------------------------------2-212222422-2---32-------------------------------------------2------------------------225242---------1-----------------1---------------------------------------------------------------------------2---------------------------------------------------------------------------11112----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------333----------------------------------------------1-11--------------------------------------------1-----11-----1--------- 2---1-----1-----1--------------------------1------1313----1-1---------1--2------------------1------------------2---1--1----------3-1--------------------------------------1--3-------1------21-----1---
 ction (DUF2382)                      *                            *          *                        * ** *   **                       *       *  *    *  **      * *  ***                             *                                            ****                ****             ***                *           *        *         *                *             *                                                           * ********* *   **                                           *                        ******         *                 *                                                                           *                                                                           *****                                                                                                                                                                                                    ***                                              * **                                            *     **     *          *   *     *     *                          *      ****    * *         *  *                  *                  *   *  *          * *                                      *  *       *      **     *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7719] PF03090            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Replicase:Replicase family     -------1------------------------------------------------------------ -------3---1-------------------------1-11---------1----------1--------------------1-------------------------------------------------------------------------111221----211-121111121111----1---------------------------1-1-------1---------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------1--1---1-------------------------------------------1-----------11--1--21-1-----1----11-----------2----1--------------1-----3--------------------------------------------------3--1------------------------------------------112-------------------------------------------1--1-1----1--1----1--111111111111-------------------------1---------1-----11----1-----------22--------------1--------1---2-----1----------------------------------------------------------------- -1---------12--1--------------------------1----1----------------1--------------------------------------11------1311--1-1--1212-3-6-113221-1-4-13112---2-1-----1-2--1-2-------1---1------------1--1---11
                                       *                                                                    *   *                         * **         *          *                    *                                                                         ******    *** ************    *                           * *       *                           *                                                                                                                                                                                            *              *  *   *                                           *           **  *  ** *     *    **           *    *              *     *                                                  *  *                                          ***                                           *  * *    *  *    *  ************                         *         *     **    *           **              *        *   *     *                                                                   *         **  *                          *    *                *                                      **      ****  * *  **** * * ****** * * *****   * *     * *  * *       *   *            *  *   **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7720] PF10749            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2534:Protein of unknown fu  -------1----------------1-----------------------------------1------- -------1-------------------------111------11----1--------------1----1-------------1-----------------------------------------------------------------11------------------------------------------------------------11----1--1----111111-1-------1-------1------------1-------------1---------------------1------------------------------1111111-1-11------1--1---1----------1-----1---------1------111--1-11------------------------------2-111---------1--------11111111-------------------------------------------------------------------------1----1---------------------1-----------------------1------1-----------------------------------------------------------------1---1--------------11---1111111111-1-1111111111111111111212-----1111111111111111-1----11-----------------1----------11--11--------------------------1-------1111---------------------1-------------------------------------------------------------------------------- -1----1----1-----1----------1------------------1---11------1---------------1-------------------------2-2-2-----31--22---------------------------1--1-------------1-1121-----11-----1----------1--------
 nction (DUF2534)                      *                *                                   *               *                         ***      **    *              *    *             *                                                                 **                                                            **    *  *    ****** *       *       *            *             *                     *                              ******* * **      *  *   *          *     *         *      ***  * **                              * ***         *        ********                                                                         *    *                     *                       *      *                                                                 *   *              **   ********** * **********************     **************** *    **                 *          **  **                          *       ****                     *                                                                                  *    *    *     *          *                  *   **      *               *                         * * *     **  **                           *  *             * ****     **     *          *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7721] PF06348            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1059:Protein of unknown fu  -------3-3-33432--------------3-------------1-----111--------1-2--13 ---11----------11----1--11-1---11111---1-2122-1------1--------1---2--1-------------1----------11-------1-----------------------------------------------------------------------------------------11-11-1-1111111-1--------------------1----------------1--------------------------------1------------------------------------------------------------------------------1--------------1--------------1---------------------------11--122-113-1111-------------------------------------------------------------------111-111111-----1111------1-11111--111------1121-1--1-----------------1---1----------------------1-11----------------------------------------------------1-----------------------------------------------------------------1----------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----1---22-------11--1--------------1---------1--1----11-----------------------1--------1----12--------1-1--112------------------1---------1------------1------1--11-2-11---1------------1-11-------1--
 nction (DUF1059)                      * * *****              *             *     ***        * *  **    **          **    *  ** *   *****   * **** *      *        *   *  *             *          **       *                                                                                         ** ** * ******* *                    *                *                                *                                                                              *              *              *                           **  *** *** ****                                                                   *** ******     ****      * *****  ***      **** *  *                 *   *                      * **                                                    *                                                                 *                *                                                                                                                                                                                        *   **       **  *              *         *  *    **                       *        *    **        * *  ***                  *         *            *      *  ** * **   *            * **       *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7722] PF09501            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Bac_small_YrzI:Probable sporu  -------1-----1-1---------------------------------------------------- ----------------------------------------------------------------------------------------11--------------1-1----------------------------------------2------------------11-----------------------1156-55-6-355565421-121--7-1-2---------1----1-11-11---11------------------------------------------------------------1-----11----------------------1----------1--------3----------1--------------------------1-------------------------------------------------------------------------------1-----1--1-------------------------1------------------------------------------------------------------1--------1---------------------1------------------------------------1--------1------------------1-------------------------------------------------------------------1---------------1------------------------------11-111-----------------------------------------------------------------11---1-------------------1------------------------------ 121-----1-------------------------------------1----------------------1-------11----------------------2--22-----13-311------------1----------------------------1---31-11---1-1------3111---321-----1----
 lation protein (Bac_small_yrz         *     * *                                                                                                                                             **              * *                                        *                  **                       **** ** * ********* ***  * * *         *    * ** **   **                                                            *     **                      *          *        *          *                          *                                                                               *     *  *                         *                                                                  *        *                     *                                    *        *                  *                                                                   *               *                              ** ***                                                                 **   *                   *                               ***     *                                     *                      *       **                      *  **     ** ***            *                            *   ** **   * *      ****   ***     *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7723] PF07435            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 YycH:YycH protein              ----------1--------------------1--------------1----1---------------- ---------------------------------------------------------------------------------1--------------------1--------------------1------------------------------------------1-----1-1----11---------211121331211111111111111221211112111111111111111121111111111111111111111111111111111---1-------1--------------------------1---------111-2-------1-----------1---2-----------2----1------------------------------------------------------------------------------------------------------------------2-----------------------------------------------------------------------1------------------------------1-1---1-----------------------------1-----------------------------------1-----------------1---------------------------------------1-----------------------------------------------------------------------------------1-------------------------------------------------------------------------------------1-------1-1------------1-1---- 11--121--------------1-1----------1------------------------------1-------1--1----1-1---1-----1-----1----------1--1---------------1--------------------------------111-1--11---1---------12--2-3----111-
                                          *                    *              *    *                                                                                                  *                    *                    *                                          *     * *    **         ************************************************************************************   *       *                          *         *** *       *           *   *           *    *                                                                                                                  *                                                                       *                              * *   *                             *                                   *                 *                                       *                                                                                   *                                                                                     *       * *            * *     **  ***              * *          *                              *       *  *    * *   *     *     *          *  *               *                                *** *  **   *         **  * *    *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7724] PF12200            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3597:Domain of unknown fun  ----------------1---------------------------------1----------------- 1-1-----------------------------------11----------1-------------1----1-------------------11------------------------------------1-2----1--------------------------------------------------------------------------------------------1---1-------------------------------------------------------------------------------------------------------------------------1------------------------------111111211212111111111111-22132222----111--1-111--1-------1------11111111-11111--------------------------------1-1-------------1------13--------111---1---1------1-1--1-------------------1-------------1-1-------------1--------------------------------------1---------------------------------------------------1---------------------------1-------------------------------------------------------------------------------1--------------1---------------------------1---------------1--------------------------------------1--------------1--- --------11-2-----1-5------2------1-1-------------------1-8------------1--------11--11---1----11------2-2---1-----1-----------------1---------------------------2-113-2-----1---1111---2---121------3-12
 ction (DUF3597)                                *                                 *                  * *                                   **          *             *    *                   **                                    * *    *                                                                                            *   *                                                                                                                         *                              ************************ ********    ***  * ***  *       *      ******** *****                                * *             *      **        ***   *   *      * *  *                   *             * *             *                                      *                                                   *                           *                                                                               *              *                           *               *                                      *              *            ** *     * *      *      * *                   * *            *        **  **   *    **      * *   *     *                 *                           * *** *     *   ****   *   ***      * **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7725] PF11184            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2969:Protein of unknown fu  ------------------1-----1-----------1------------------------------- -------------1--------------------------------------------------------------------------1131-1----------1-3-1------------------------------------2-12-------------------1--------------------------------------1-------1-1111---------1--111-1--1---1-1-----2211111111111111111111111111111111111111111111111111111111111111121111---1-33311111-1--11------1----------------------1-----------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------111111----------------------------------------1--------------------------111-1--1-----11---------11111--------------------1--------11-------------------------------1-------------------------------------------------------------------2-------------------------------------1-1------------------------------------ 1--1--1-----13---------------1----------------1-----------------------1----------------------------------1--1-----------------1--------------------------------11---------1---1-----------------1--1---
 nction (DUF2969)                                 *     *           *                                             *                                                                          **** *          * * *                                    * **                   *                                      *       * ****         *  *** *  *   * *     **********************************************************************   * ******** *  **      *                      *                                               *                                                                                                                                                                        *                  ******                                        *                          *** *  *     **         *****                    *        **                               *                                                                   *                                     * *                                     *  *  *     **               *                *                       *                                  *  *                 *                                **         *   *                 *  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7726] PF01517            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 HDV_ag:Hepatitis delta virus   -------------------1---1-------------------------------------------- 1---1------------------------------1---1---1----2----1-------------1-------------------------------------------------------------------------------------------------------------1------1-----------------------1----------1------------------------------1----------------------------11-----------------------------------------------------1-1--------------------------------1---------------------------------------------------------------------------1----------------------------------------------------------------1--------------------------1------------1-------------------1--------2-------------------1------------------------------------------11----1111-1--1-----------------1----------------------------------2---1-------------------------------------------------------------------------------------------------------------------1-----------------1---------1-----11-------------------------------------------------- --11-12-1--1-----1--1-11--111-224--1-1-11---111-311231-1-1-111-----1-------1--1--1-1----------1-211--1-1-1--1-2-112-2-11----11---------11--12-11211-11--1-1123112--1111-12111---1-14---115313-2-1-1----
 delta antigen                                     *   *                                             *   *                              *   *   *    *    *             *                                                                                                             *      *                       *          *                              *                            **                                                     * *                                *                                                                           *                                                                *                          *            *                   *        *                   *                                          **    **** *  *                 *                                  *   *                                                                                                                   *                 *         *     **                                                     ** ** *  *     *  * **  *** ***  * * **   *** ****** * * ***     *       *  *  * *          * ***  * * *  * * *** * **    **         **  ** ***** **  * *******  **** *****   * **   ****** * * *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7727] PF04578            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      433          
 DUF594:Protein of unknown fun  ---------------------1----------------------1----------------------- --1--------1---------------------111-----1---1----------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------1-1-----------1---------------------1-------------------------1----------------------------------------------------------------------------------1------------------------------------1-------------1--------------1----1------------1---------------1---------------------1-11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11--1111-111---------------------------------------------------------------- ----------------1----------11------------11--------------1--1-----------------1-----------2-11-------1------2---------------1----------------------------2----1----1------------1---------50716-----1--
 ction, DUF594                                       *                      *                          *        *                     ***     *   *                                                                                                                *                                                                                                                               *                                                                                       * *           *                     *                         *                                                                                  *                                    *             *              *    *            *               *                     * **                                                                                                                                                                                                * **  **** ***                                                                                 *          **            **              *  *                 *           * **       *      *               *                            *    *    *            *         *****     *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7728] PF11075            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2780:Protein of unknown fu  ------------------------1------1------------------11---------------- -------------------------1---------------------------1----------------------------------------------------------------------1--------------------------------------1-1----------------111--------11111--1------------------1--------------------------------------------------------------------------------------------1---------------------------------------------1-------------------------1-1-----1111-111-1111111-11111-11-1--11-11111-111-----1----------------------------------------------------------------------------------------------------------------------------------11---------------------------2-----------------------1---------1--2-2--1111111111111111111---1----------1-----------------------------------------------------------------------------------------------11-2-------------------------2-11111111-1121-112----------11111111111111--------------------------1----------------------------------------------- --------21-----1-------------1--------1-2---------------------1--------------------------------------11-----21--1111--------11------------------1-11------1---1------1-1----2-1-1--1-----1--11112-337--
 nction VcgC/VcgE (DUF2780)                             *      *                  **                                          *                           *                                                                      *                                      * *                ***        *****  *                  *                                                                                            *                                             *                         * *     **** *** ******* ***** ** *  ** ***** ***     *                                                                                                                                  **                           *                       *         *  * *  *******************   *          *                                                                                               ** *                         * ******** **** ***          **************                          *                                                        **     *             *        * *                     *                                      **     **  ****        **                  * **      *   *      * *    * * *  *     *  ***** ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7729] PF09164            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 VitD-bind_III:Vitamin D bindi  ------------------------1----1----------------1--------------------- -----1---------------------------------------11--------------------111--------------------1-------------1-------------------------------------------1---------------------------------------------------1-12--1-------111-------------------------------1-1----1--1----------------------------------------------------------------1-----------------------1------------------------------------1-------------------------1-------------------------------------------------------1-------------------------1------1---1-------------------------------------------1----------------------------------------------------------------------------------1-1----------------------1--1------1-------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------- ------1-211------------2-1-1------1--1111-1-121---1-----1----1-1-111--1321-11--11-------122---11-----1-1-2--112-2--311111111321212-1-21111222123-112111115-1111---3-11131-3-1---11------111-2---12-----
 ng protein, domain III                                 *    *                *                           *                                       **                    ***                    *             *                                           *                                                   * **  *       ***                               * *    *  *                                                                *                       *                                    *                         *                                                       *                         *      *   *                                           *                                                                                  * *                      *  *      *       *                                                                                                                                                                      *                                                                                 * ***            * * *      *  **** * ***   *     *    * * ***  **** **  **       ***   **     * * *  *** *  *************** * *********** ********* ****   * ***** * *   **      *** *   **     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7730] PF10039            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2275:Predicted integral me  -------------------------11----------------------------------------- -----------1--111----111-2------1211-------1----1-11-1---1----1-1---1------------1------------------------1-1-----------------------------1-111--111-111----------------11------------1---------2-----------------22-1-----1-11--11-1--1-111111-1111111--------------------1------------------------------------------------------1--2--------1--1--------------1--1122-1----111------1-11-----------1---1---------------------1----12--1-------1---------2------------------------1--------------------------------21-------------------------1-----------------------------------------------1------------1--1--------11--------------------------------1--1---------------------------------------1------------------------------------------------------------------------------------------------------1111----------1--11------------11----1----1------------------1--------------------------------------------1---------------------------- 1-----------111--1--21-1-----------1------------1--1---1--------------------------------1----12---1-----11-2--1-------------121--2---12---1------11-----1-----2---11111----11--112---------1--12-------
 mbrane protein (DUF2275)                                **                                                     *  ***    *** *      ****       *    * ** *   *    * *   *            *                        * *                             * ***  *** ***                **            *         *                 ** *     * **  ** *  * ****** *******                    *                                                      *  *        *  *              *  **** *    ***      * **           *   *                     *    **  *       *         *                        *                                **                         *                                               *            *  *        **                                *  *                                       *                                                                                                      ****          *  **            **    *    *                  *                                            *                             *           ***  *  ** *           *            *  *   *                                *    **   *     ** *  *             ***  *   **   *      **     *     *   *****    **  ***         *  **       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7731] PF11140            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2913:Protein of unknown fu  ------------------------------------1----------------------11------- ---------------11-----------------------------------------------------------11-----------------------1-------------------------------------------1--1------------------1--------1--------------------------------------------------------11111112211122---1--------1-1---------------------1----------------------------1---------1--------------------------------1--1---------1---------------1-------2---------------------------------1----------------------------------------------------------------1---------------------------------------------------------------1-----------1-----------------------1-------------------------------------11---11---11223331111111121112----------------------------1-----1---------------2------1-1------1-1----1--------1----------------------11-------------------------------------------------------------41142122242122----------1111--------1-----1------1-------------------------------------- -1-1----3---11-----------------11-1-----------------1--1------------1--1--1-----2-----------------------1----1--1--1------------------------1----1-1-1-----1-------5--13---1-1---1-------1----4-1---2--
 nction (DUF2913)                                                   *                      **                       **                                                           **                       *                                           *  *                  *        *                                                        **************   *        * *                     *                            *         *                                *  *         *               *       *                                 *                                                                *                                                               *           *                       *                                     **   **   ********************                            *     *               *      * *      * *    *        *                      **                                                             **************          ****        *     *      *                                        * *    *   **                 ** *                 *  *            *  *  *     *                       *    *  *  *                        *    * * *     *       *  **   * *   *       *    * *   *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7732] PF01439            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      11           
 Metallothio_2:Metallothionein  --------------------------------------------1----------------------1 ---------------------------------------------------------------------------------------------------1-----------------------1-----------11111---1----------------------------------------------------11111-111111------1-1----------------111111111111-11--1------------------------------------------------------------------------------------2-1----------------------------------------------------1-------------------------1-------------------------------------------------2------------------------------------------------------------1-----------------------------11------1-------------------1-1------------------1-----------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------1- ------1----------121--11--1-12---111112221211111112---------11--2----------1------1--1--1-22-2-------2---1---14-----1--------1--1-----------------1----------------14151--2--4------1-1-1-238-6-------2
                                                                            *                      *                                                                                                    *                       *           *****   *                                                    ***** ******      * *                ************ **  *                                                                                    * *                                                    *                         *                                                 *                                                            *                             **      *                   * *                  *                 *                                                                                                                                                                                                                                *                                                               *        *          ***  **  * **   ******************         **  *          *      *  *  * ** *       *   *   **     *        *  *                 *                *****  *  *      * * * *** *       *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7733] PF11859            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3379:Protein of unknown fu  ----------------------------------------------1---------------1----- --1------------------------------111-------------------------11---------------1----------11--1------2-1------------------------------1-----1---1---------1--------1----------------------------1--------------1-11--1-----1--1-------------------------1-------------------21-------------1-1------------------------------------1---11111-1------------1-----------2-----1--------------------1----1---1-----------------------------------------------------------------1-------1---------------------------1---------1---11--1-111--1-11--------------1----2---------------------------1----------------------------------------------------------1111--1-2121111111111112111122-----1-----------1----------12--1-11--111------------1--------------------------11--1---------------------------------11---------111111--------------------------------2--111111121111------------------11---------------------------------------------------1-- 111--1----1-1------1--------1------1-------------1-------11-----2----1-1------------1--------------1----2-------11------1---1---11-1------------------------11--3-1-211-1----------------1----1--------
 nction (DUF3379)                                                             *               *        *                              ***                         **               *          **  *      * *                              *     *   *         *        *                            *              * **  *     *  *                         *                   **             * *                                    *   ***** *            *           *     *                    *    *   *                                                                 *       *                           *         *   **  * ***  * **              *    *                           *                                                          ****  * **********************     *           *          **  * **  ***            *                          **  *                                 **         ******                                *  ************                  **                                                   *   ***  *    * *      *        *      *             *       **     *    * *            *              *    *       **      *   *   ** *                        **  * * *** *                *    *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7734] PF08945            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 Bclx_interact:Bcl-x interacti  ------------------------------------------------1------------------- -------------------------------1----------------------------------1-------------------------------------------------------------------------------------11-----------1------------1----------------------------------------------1111------1----------------------------------------------------------------------------------------------------------------------------------------1--------------11--------111-11--11------------------11---------1--11-------------------------------------------------------------------1---11---1---------1----------1----------------2-------------------------------------------1----------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------1----1------------------------------------------------------------------------------------------------------------ ---------------1-1--------1--11--221--1-11----------------------------1--1----------1-1---3------------1-----13-13-11321-213911716-4-93912112-115-221121-322-11---------1----------------1--1----------
 ng                                                                             *                                                   *                                  *                                                                                     **           *            *                                              ****      *                                                                                                                                        *              **        *** **  **                  **         *  **                                                                   *   **   *         *          *                *                                           *                                                                                  *                                                                                                                      *    *                                                                                                                            * *        *  **  ***  * **                            *  *          * *   *            *     ** ** ***** ********* * ******** *** ****** *** **         *                *  *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7735] PF10407            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Cytokin_check_N:Cdc14 phospha  --------------------------------------------------11--1------------- ----------------------------------------------------------------------------------------------------111------------------------------------------------------------------11----------------------111111211211121-----11-1---11-------1-------------------1----1---------1------------------------------------------------------------------1-1-----------1---1-------------1----------------------------------------------------------------------1-------------------------------1---------1-11----------1-------------------------------------------------------------------------------------------------------------1---------1---------------111--------------------------1--1-------------------------------------------------------11---------------------------1--1-111---------------------------1--------------------------1------------------------------1--------1------------111-------------------------------1---------------------- --3-23-----1-1---1-12111111111-1111111-111-111------1---1-----211111-12211132222111121121------------------1-11------1-----1-----1-----1----------------21-----133-2121-11---11----------1--3------2--1
 tase binding protein N-termin                                                    **  *                                                                                                                  ***                                                                  **                      ***************     ** *   **       *                   *    *         *                                                                  * *           *   *             *                                                                      *                               *         * **          *                                                                                                             *         *               ***                          *  *                                                       **                           *  * ***                           *                          *                              *        *            ***                               *                         * **     * *   * *********** ******* *** ***      *   *     ****** ********************                  * **      *     *     *     *                **     *** **** **   **          *  *      *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7736] PF04806            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                11                  1                                                                                                                                                                                                                                                                                                                                                      1                                                                       
 EspF:EspF protein repeat       -------------------------------------------------------------------- 1----1--------------------------------3-------------------------1--11------------------------1----------1------------------------------1--1------1--------11----------------------------1-------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1--------------------1---111-2-------------------------------------------------------------------------------------1--------------1-----------------------1--------------------111--------------------------------2-----------------------------------------------------------------------------1---35--------7----3----4-------------------------------------------------------------------------------------------------1-------1---1--1----------------------------------111-------------------------------------------------------------1-- -----------1---2-1-1----1----1211------------222--11-1-1-11-11------------------------11------1-----23-1----311------12--1--11-121---2-2--------1-1----1----1-4----2--1-1---11---1------1---1------2-1-
                                                                                                     *    *                                *                         *  **                        *          *                              *  *      *        **                            *                                                                   *                                                                                                                                       *                    *   *** *                                                                                     *              *                       *                    ***                                *                                                                             *   **        *    *    *                                                                                                 *       *   *  *                                  ***                                                             *              *   * * *    *    ****            ***  ** * * ** **                        **      *     ** *    ***      **  *  ** ***   * *        * *    *    * *    *  * *   **   *      *   *      * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7737] PF11651            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 P22_CoatProtein:P22 coat prot  -------------------------------------------------------------------- --3--2-1-12---1--11-1---1-1111111---2--2----2---------------11--1---------------------------------------------------------------1--------------1-------1--------------------------------1------------------------------------------------------------------------------1-----------------1111--------------1111-11111111---111-----------------------1--------------------------------1---1--------11--------------------1---1-1-----------------1-----------------------11----1-------------------------------11--------------1111---11112---1--------1--------------------1--------------------------1-----------------------------1-----------------------1-------------------11-------------1-----------1-2-11---2-----1-1------122-------1-11---1-1----11---111-----------------1----------1---------------------------1-1------1---1------1-------------1----------1---------1-2---------11------------------------------------1------------1 ------1-32----------112-------------1----------1----------------------------1------------------------1--1------------------11-11----------------1-----1----1---------1--111-1-----1---11-----11---111--
 ein - gene protein 5                                                                                  *  * * **   *  ** *   * *******   *  *    *               **  *                                                               *              *       *                                *                                                                              *                 ****              **** ********   ***                       *                                *   *        **                    *   * *                 *                       **    *                               **              ****   *****   *        *                    *                          *                             *                       *                   **             *           * * **   *     * *      ***       * **   * *    **   ***                 *          *                           * *      *   *      *             *          *         * *         **                                    *            *       * **          ***             *          *                            *                        *  *                  ** **                *     *    *         *  *** *     *   **     **   ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7738] PF10420            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 IL12p40_C:Cytokine interleuki  -------------------------------------------------------------------- ------1----------------------------------------------------------------------------1-----------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------- --1-----11-1--1-1---1-----1----1-1---1111------1-------1------------------------------------1-----------------14677433113352441323-3-33523233223323131242224322--1--121-----1-1-1--------1--2-21----2--
 n-12p40 C-terminus                                                                                        *                                                                            *                                                                             *                                                                                                                                                                                                                               *                                                                                                                                            *                                                                                                                                                                                         *                                                                      *                                                                                                                                      *     ** *  * *   *     *    * *   ****      *       *                                    *                 ******************** * **************************  *  ***     * * *        *  * **    *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7739] PF11834            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1 1        
 DUF3354:Domain of unknown fun  -------------------------------------------------------------------- --------1-2---------------------------------------1--------------------1--------------------------------1-2--------------------------1------------------------1--------------1--1----------------------------------------------1-----------------------------------------------1------------------------------------------------------3---------------11--1-------------------------------------------------1---------------------------------------------------------------------------------------------------1---------------------------------------------------------------------1--11-------------------------------1-1------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------111-------------1-1--------------------------------------------------------------------- 11--122-1------------1-----11-----------------11---1-------11-1----2-------------11------------------2------3132223421-1111112-122-2-33211111-111111111113211111-1-2-1----2-13--1----1----434-01---212-
 ction (DUF3354)                                                                                             * *                                       *                    *                                * *                          *                        *              *  *                                              *                                               *                                                      *               **  *                                                 *                                                                                                   *                                                                     *  **                               * *                                                                                                                                          *                                                                                   ***             * *                                                                      **  *** *            *     **                 **   *       ** *    *             **                  *      ********** ******* *** * ******** ****************** * * *    * **  *    *    *** **   *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7740] PF02072            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Orexin:Prepro-orexin           -------------------------------------------------------------------- --------------1-----------------1---1----1---1------------------1-------------------------1------------------------------------------------------------1---------------1----------------------------------------------------1-----------------------------------------------------------------1------------------------------------1--------------------------------------------------1---2----------------------------2----------------------1-----------------------------1-------------------------------------------1------------1-1-11-----------------------1---------------------2--------1--------------------1-------------------------------------------------------------------------------2--------------------------------1--------------1--------------------------------------------------------------------------------1------------------------------------------1-------------------------------------------------------------1-- ------1-1--------1--------1-----2--------1-------------1----1---1-------------1-----------1--------------1-17-351322-2-41231222312-5-232-12333221211-11--213211----1--32--1--81-22-2---2-2331--1-------
                                                                                                                   *                 *   *    *   *                  *                         *                                                            *               *                                                    *                                                                 *                                    *                                                  *   *                            *                      *                             *                                           *            * * **                       *                     *        *                    *                                                                               *                                *              *                                                                                *                                          *                                                             *         * *        *        *     *        *             *    *   *             *           *              * ** ****** * *********** * *** *********** **  ******    *  **  *  ** ** *   * ****  *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7741] PF11274            177                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3074:Protein of unknown fu  -------------------------------------------------------------------- ------------------------------------------------1-------------------------------------1-----------------------------------------1--------------1---------------------------------------------------------1-------1------1--------------------------------------------------------------------------------------------------------------------------------------------1----------1-------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------2---------------------------------------------1-----------------------------------------------------------------1------------------------------------------------------1-1---------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------- 1-------2-1---12232122232331511112222222322111223222122121-313111-11-1--111---1-1111111111222-211112--12-----9-----2-1--------1--1-------1--2---1--------------11--2--1-----1------1--------11---1-----
 nction (DUF3074)                                                                                                                                    *                                     *                                         *              *                                                         *       *      *                                                                                                                                            *          *                                                                                                                                           *                                 *                                             *                                                                 *                                                      * *                                                                                                                                             *                                                              *       * *   ******************************************** ****** ** *  ***   * ************* ******  **     *     * *        *  *       *  *   *              **  *  *     *      *        **   *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7742] PF11305            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3107:Protein of unknown fu  --1-------------1-1------------------------------------------------- 1--1111111111111111-111111111111111111111121111111111111111-1111111111--11112-------------1---------------2--------------------------------1----1-------11---------1-1--2-------------------1-----------------------------------11111---------------------------------------------------------------------------------------------1---------------1-----------------------------------------------------1-----------------1----1-----------1----------------------------------------------------------------------------------1----------------------------------------------------------------------------------1-----------1-----------------------------------1------------1-------------------11--------------1------------------------------1----------------------------------------------1--1----------11----111111---------------------------------111----------------------111------------------------------------------------------------ -----------1--11-----1----1-------------------1----1-----11----1-----1--2--1-1-1--1--1---------1-----1------2------1----1-----------------1---------1------112-111--21------11----1---------1-----1411-
 nction (DUF3107)                 *             * *                                                  *  **************** *************************************** **********  *****             *               *                                *    *       **         * *  *                   *                                   *****                                                                                             *               *                                                     *                 *    *           *                                                                                  *                                                                                  *           *                                   *            *                   **              *                              *                                              *  *          **    ******                                 ***                      ***                                                                        *  **     *    *                   *    *     **    *     *  *  * * *  *  *         *     *      *      *    *                 *         *      *** ***  **      **    *         *     **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7743] PF11003            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2842:Protein of unknown fu  ---1------------1---1---1--1-------1-------------------------------- --2-1------1-----------------------------1---1--------------------211----11---------------------------2----1---------------------1-------------1-1-------1-------------1---------1---------------------1-----------1--------1---------1-----------------------------1--------------------------------------------------------------------1--1-------------------1-----------1---------11111-----112111111111111111111111-22122111131--221111-12111111-1121111111---------1---1--------------------------------1111------111111-111111-111111111------------------------------------------------1---------1---------1---1--------------------------1------------------11------------------------------1----------------------------------1---------------------------------------------------------1-------1------------------1----------------1------------1----------1--------------1---------21-------------------------------------------------- ----1---1----------1-----------1-------------------------------------------1---2-------------------------1----11---1-------------------1---------------------------------121----------1----1--1--------
 nction (DUF2842)                  *            *   *   *  *       *                                   * *      *                             *   *                    ***    **                           *    *                     *             * *       *             *         *                     *           *        *         *                             *                                                                    *  *                   *           *         *****     ************************ ***********  ****** ******** **********         *   *                                ****      ****** ****** *********                                                *         *         *   *                          *                  **                              *                                  *                                                         *       *                  *                *            *          *              *         **                                                       *   *          *           *                                           *   *                         *    **   *                   *                                 ***          *    *  *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7744] PF10038            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2274:Protein of unknown fu  ----1-------------1----------11------------------------------------- ----1-------------------------------2--1----------------------------------------------------------------------------------------1-----11------------1211----11--1-----------------------1----------------1----------------------------------------------------1------------------------------------------------------------------------------------------------1-1---------------------4111------13-4-2224--1111-111-111-------1-333-------------141----4----------------65-2--1------------------1------------1121-21122----1-----11------1-------2--221--12231-----------------------------1-------------1-1--------1------------------------------1------------------1----------------1-------------------------------------------1111----------------------------------------------------1------------------1-------------1---1---------------------------1----------11---------------------------------------------------------------------2-- --------21---------------------------1-1111------1---------------------------------------22--1----------1-------------------1--------------------1-------------------1-11---1-----1--------1------13-1-
 nction (DUF2274)                   *             *          **                                          *                               *  *                                                                                        *     **            ****    **  *                       *                *                                                    *                                                                                                * *                     ****      ** * ****  **** *** ***       * ***             ***    *                ** *  *                  *            **** *****    *     **      *       *  ***  *****                             *             * *        *                              *                  *                *                                           ****                                                    *                  *             *   *                           *          **                                                                     *           **                           * ****      *                                       **  *          *                   *                    *                   * **   *     *        *      ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7745] PF06819            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Arc_PepC:Archaeal Peptidase A  -----1--1-------------2----------1111111111----------12111111------- -1------111---------------------------------------------1-------------1-------------1-----------------1-11---------------------------------1-----1-1-------------------------------------------2------------------11-------1--2----------1---1---1--1-1-------------------------11-----------------------------------------------------121-----1------------1---1---------2--11-----------------1-------------------------------------111---------1-------------11111111------------------------------------------------------------------------------------------------------------------1-----1--11---1-------------------------------------1-----------------12----------------1---1----------------1111111-1--1111111111111111111-------------------------1111111---11111111111---------------------------------1----------------------------------------1---------------------------1-----------1-----------------1-----1-1------------------- 1---3-------------1---1---1-----11------------1---1----------------1-1-----------12111---------1---1---------1---------1-------------------1--------1-------------121----1-11------2----1---3--1-------
 24 C-terminal Domain                *  *             *          **********          ********         *      ***                                             *             *             *                 * **                                 *     * *                                           *                  **       *  *          *   *   *  * *                         **                                                     ***     *            *   *         *  **                 *                                     ***         *             ********                                                                                                                  *     *  **   *                                     *                 **                *   *                ******* *  *******************                         *******   ***********                                 *                                        *                           *           *                 *     * *                    *   *             *   *   *     **            *   *                * *           *****         *   *         *         *                   *        *             ***    * **      *    *   *  *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7746] PF07663            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 EIIBC-GUT_C:Sorbitol phosphot  ------1-----------------------1-------------------12-----------1---- -------1-------------2111-------1--11----2----1----------------1----------------1----1--------------------------------------------------22------------------------1---------------------------------------------21111-----------111111-----------------1----1---11-----12--11-1-----------111-11---------------------------------1----11111111-21-2--------1---------------------------1-------------------------------1------2---2----------1---1-----------------------------------------------------------------1------------------------1---------111--------1-1------1-----------------------------1---1----------------------------------------112---------------------------1------------1------1-11111111--1111-1111-1211111-212-----1111111121112111111-11-1--1--------------------------------1--------111---------------------------------------------------------------------------------------------------------------------1-1------- ----------1-------------------------1------------11------------------------------------------------------1--1--11-------1-------11-1-112-------------1---11---1-----------------------------3----------
 ransferase enzyme II C-termin        *                       *                   **           *            *             ****       *  **    *    *                *                *    *                                                  **                        *                                             *****           ******                 *    *   **     **  ** *           *** **                                 *    ******** ** *        *                           *                               *      *   *          *   *                                                                 *                        *         ***        * *      *                             *   *                                        ***                           *            *      * ********  **** **** ******* ***     ******************* ** *  *                                *        ***                                                                                                                     * *                  *                         *            **                                                      *  *  **       *       ** * ***             *   **   *                             *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7747] PF07285            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1444:Protein of unknown fu  -------------1----1----------------------------1-------------------- ----1--1------------------------------------------------------------------------------------------1---1--1-----------------------------11111---3--11-------------------1-----------------------1122222122112211212111121111111111111111-11111111111111112211-------------11-----1-------------------------1----------------------1------------1----------1-2--1-1-----12--------------1---------1-1----------------------------------1------------------1-------------------1-------------------------------------------1----1---------------1-1------1------------1----1------------------------------1--------------2-1--1-----------1------------------1----1-1----------------------------------------------1--1--1-------1---------------------------------1--------11111-1--1---------------2-------1--------------------1-----------------------------1------------------------------------------------------------------------------------- ------------------1-----1-------1--1-----------------1---1---------------------------1--1------1---------3----211------------------------------------------------1---111--1---1------1------1-----312--
 nction (DUF1444)                            *    *                            *                         *  *                                                                                          *   *  *                             *****   *  **                   *                       **************************************** ********************             **     *                         *                      *            *          * *  * *     **              *         * *                                  *                  *                   *                                           *    *               * *      *            *    *                              *              * *  *           *                  *    * *                                              *  *  *       *                                 *        ***** *  *               *       *                    *                             *                                                                                                        *     *       *  *                 *   *                           *  *      *         *    ***                                                *   ***  *   *      *      *     ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7748] PF09808            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 SNAPc_SNAP43:Small nuclear RN  --------------1----------11--------------------------------1-------- ---------------------------------------1-------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------1------1-------------------------------------------------------------------------------------------------------------------------------------1---------------1--1-------------------------------------------------------------------1-----------------1-----------------------------------------1---11-1111--------------------------------------------------1------11-------------------------------------------------------------------------1----------------------------------------1------------- 11--11--311-22---------------------------11-------------1---------------1------------------1-211-------121-1-2223222111-1122111113-2-11121112211111111121222121-1123111111-1531-21-2111212113-411-2112-
 A activating complex (SNAPc),                *          **                                *                                                *                                                                                                       *                                                                                                                                                                                                                                                         *                                   *      *                                                                                                                                     *               *  *                                                                   *                 *                                         *   ** ****                                                  *      **                                                                         *                                        *              **  **  *** **                           **             *               *                  * ***       *** * ********** ********** * ************************** ********** **** ** ********** *** **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7749] PF10995            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2819:Protein of unknown fu  ----------------1------------1---------------1---------------------- --------------------------------------11-----------------------------------------1-------------------------------------------------------------1---1-------------1---1---------------------1----------1-------1------------------21------------------------1----------------------------------------------------------1----------------------------------------------------------------1---------------------------------------------------1------1------1122--------------------------------1------------------1--1----111111-111-112-1111-1112-1-1-----------------------1---------------------11-1-----------------------------------------------------1---11----------1---------------------11---1-111111111--12-121112111211111111111---111111111111111-111-11-1--1-----------------------------------1--1--------------------------111-11-1----------1111------------------------------------------------------------------------------------ ----111----1-----1-----1------1---------------11----1-11-------------1--------------------1----1------11-1-111---------------1-----------------1-----------------1---1-1--1212-1-11----------------311-
 nction (DUF2819)                               *            *               *                                                             **                                         *                                                             *   *             *   *                     *          *       *                  **                        *                                                          *                                                                *                                                   *      *      ****                                *                  *  *    ****** *** *** **** **** * *                       *                     ** *                                                     *   **          *                     **   * *********  ** *********************   *************** *** ** *  *                                   *  *                          *** ** *          ****                                                                                         ***    *     *     *      *               **    * **             *                    *    *      ** * ***               *                 *                 *   * *  **** * **                *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7750] PF06910            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 MEA1:Male enhanced antigen 1   -----------------1-------------------------------------------------- ------------1----11-1----111111-----1-------1-----1-----1-----------1------1-------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------1--1----1----------------------------------------------------------------1------11-----------------------------------------------------------------1---------------------------1-1--1--1-----------------------------1---------------------------------------------------------------------------------2------------------------------------------1---------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------- ----111----2--1--1-1----1--1-------1----------2-1--112----1-11-----------1---------------11---1---1----1-1-1--1122122123122133-218-1-2131112311422111-4--11-121--1-31312451--11---21-----1115------1---
 (MEA1)                                          *                                                               *    ** *    ******     *       *     *     *           *      *                                                                                                                                     *                                                                                                                                                     *  *    *                                                                *      **                                                                 *                           * *  *  *                             *                                                                                 *                                          *                                                                                                                     *                                                                                                        ***    *  *  * *    *  *       *          * *  ***    * **           *               **   *   *    * * *  **************** *** * **************** *  ** ***  * ********  **   **     ****      *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7751] PF10731            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 1                                 
 Anophelin:Thrombin inhibitor   ------------------1------------------------------------------------- --------------------------------------------------1----------------------------------------1-----------------1-------------------1-1---1--------------------------------------------------------------------------11-------------11-1----------------------------------------------------------------------------------------------------------------------2-----------------------------------------------------------1---1--1---------------1--------1--------11111111-----------------------------------------------------1-------11----1-11--1------1---------1-----------------------2------1-1-----2-------------1---------------------------11----------------------------1--------------------------------------------------1----1---------------------------------------------------------1----1--------------1-------1---------------1--------------------1------------------------------------------------------------------------------ ---1----------1112----1-----1-2---------------------11--1--1---------------1-----112--------11-1-----1---1--2-2-1112----21----12-6-21411-1111------------1-----112--102352-131--1-121-2---254142--11-2-
 from mosquito                                    *                                                                                                    *                                        *                 *                   * *   *                                                                          **             ** *                                                                                                                      *                                                           *   *  *               *        *        ********                                                     *       **    * **  *      *         *                       *      * *     *             *                           **                            *                                                  *    *                                                         *    *              *       *               *                    *                                                                                  *          ****    *     * *                     **  *  *               *     ***        ** *     *   *  * * ****    **    ** * ***** ****            *     ***  ****** ***  * *** *   ******  ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7752] PF09945            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2177:Predicted membrane pr  ------------------11----------------------------------------1------- ----1--------2---------------------------------------12-------11----1-----------------------1-------1-------------------------------------1-114-1----11---------------123--------------------------1----------------2--1----1-1-111111-1----------------------1------1-------------111--------------------1---------------------------------------1-------------1---------------1------1-11------1-11---11222----------------1----11-1221-1-211--2--1----1111-----------1-----1-------------------------------111--------------------------------1--11----11----------1--------------------1-1-11--1----------2--11-------------------------------------1----1------1-1------1--------1-----------------------------1-----------------------------------------------------------------------1111--------1------------------111--1111-1121---1-221--------------------------1-------------------------------1--------------------------------------- ----11-----------------1-1----1-------------------12-2-------------1---------------------------11111---1----11-----1-------------------------------------1---------2------1-1--12-----1-1-------11--11-
 otein (DUF2177)                                  **                                        *            *        *                                       **       **    *                       *       *                                     * *** *    **               ***                          *                *  *    * * ****** *                      *      *             ***                    *                                       *             *               *      * **      * **   *****                *    ** **** * ***  *  *    ****           *     *                               ***                                *  **    **          *                    * * **  *          *  **                                     *    *      * *      *        *                             *                                                                       ****        *                  ***  **** ****   * ***                          *                               *                                            **                 * *    *                   ** *             *                           *****   *    **     *                                     *         *      * *  **     * *       **  ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7753] PF09904            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2131:Uncharacterized prote  ------------------------1-------------------1----------------------- ---------------------1-----------------------------------1--1-------------------------------------------1------------------------------1-----------1------------------11------------------------------------1------1---1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------1------1---------1-------1-------112---------------------------------------------------1---------2111111----11-----1--11----1-----------1-------------------------------------------------------------------------------------11--------11111111111112111111---------------1-1---11-----1--3---11---12-1--------------1------1---1-1--11--------111111111111-----1----1-1---1---------------------------111111122111111111----------11321111122111------------------------------------------------------------------------1- -----------1-----1---1--------------1-------1-1-------------------------------------1----------2---------------2--1-1-----------------------------------1-----3--1---1---3---1------1----2--2--1-1----8
 in conserved in bacteria (DUF                          *                   *                                             *                                   *  *                                           *                              *           *                  **                                    *      *   *                                                                                                                                                                       *                       *      *         *       *       ***                                                   *         *******    **     *  **    *           *                                                                                     **        ********************               * *   **     *  *   **   ** *              *      *   * *  **        ************     *    * *   *                           ******************          **************                                                                        *             *     *   *              *       * *                                     *          *               *  * *                                   *     *  *   *   *   *      *    *  *  * *    *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7754] PF06174            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF987:Protein of unknown fun  ---------------------------1--11------------------------------------ --2-----------1-----------------------11-11--------------1--1---------------------------1---------------1--------------------1--------------------------1-------1-------------------------------1-----------------1111---------1--------------------------------------------1------------------------------------------------------------------------------------1-----1--------------1----------------------------------------1----------------------------------------------------------------------------------------1--------------11111----111----------------------------------------1---------------1----------1---------------------------------1-----1--------------------------1------1--1-1-3226335-3--213-515-34242--31---1------2121111121111111--1211----------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------- -1---------------1-11--1---------------------------2--------1-------------------------------------------1---2--1-3-1-------------3-1-1-1-------------------1---1---3--------2----11------21---1----1-1-
 ction (DUF987)                                            *  **                                       *           *                       ** **              *  *                           *               *                    *                          *       *                               *                 ****         *                                            *                                                                                    *     *              *                                        *                                                                                        *              *****    ***                                        *               *          *                                 *     *                          *      *  * * ******* *  *** *** *****  **   *      ****************  ****                                                                                                    **                                                                            *               * **  *                           *        *                                           *   *  * * *             * * * *                   *   *   *        *    **      **   *    * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7755] PF07290            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1449:Protein of unknown fu  ----------------------------1-----------------2--------------------- ---------------------1---------------1-----1-------------------11----1------------------------------------------------------------------11-----3--111--------------11-----------------------1------------------------1--------1------------------------1--1-------------1----------1-----------------1-------------------------------------------------------------11-1------------------------2--1----------------------11111---1-------11-112--------12---1-1-------------------------------------------------1----------------------------1-----------------1-------1-------------------1-------------------1--------------1-----1-------------------1-------11111-1-111111-11-2--------------------1111111111--111111111111111111--------1-11111111111111-------1-----------------------------1-----------------1111111-----1-11----------------------------------------------------1----------------1----------------------------------------- ----11--------------1-------------------------33----1-111-------------1----11----------------1-----------1---1------------11-1-----1--2-1-1---------1--------1---112---1-11---1-1--------1-1----11-11--
 nction (DUF1449)                                           *                 *                                           *               *     *                   **    *                                                                  **     *  ***              **                       *                        *        *                        *  *             *          *                 *                                                             ** *                        *  *                      *****   *       ** ***        **   * *                                                 *                            *                 *       *                   *                   *              *     *                   *       ***** * ****** ** *                    **********  ******************        * **************       *                             *                 *******     * **                                                    *                *                                              **              *                         **    * ***             *    **                *           *   *            ** *     *  * * *         *        *   ***   * **   * *        * *    ** **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7756] PF04094            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF390:Protein of unknown fun  -------------------------------1------------------------------------ -------------2-------1---1-------222---1-1--1---------1------------11-1------------------------------------1------------------------------1---------1---------------------------------1---------------------------11----1----------------------------------------------------------111------------------------------------------------------------------------------------------------1---------------1------1--------------------------1--------1------1-------11111111----------------------------------------1---------------------2----------------1-----------------------------------------------------------2-121---1----------1-------------------1------1111------------1----------------------------1--------------------------1--------------------------------------------------------1----1----------------------1-----------------1-------------------------------------------------------------------------------------------------- -1--1-1----222-1----------2--3211111-----1-2211-1-1-2---1--1--1-------1-----1-------1-----11--14-1--1--1-2-2--5---2-1---2---2--1-------1--1---111--------1-21-1--1-1--32113--1----1-1-2-12-2123-1-11-11
 ction (DUF390)                                                *                                                  *       *   *       ***   * *  *         *            ** *                                    *                              *         *                                 *                           **    *                                                          ***                                                                                                *               *      *                          *        *      *       ********                                        *                     *                *                                                           * ***   *          *                   *      ****            *                            *                          *                                                        *    *                      *                 *                                                                                                    *  * *    *** *          *  *******     * **** * * *   *  *  *       *     *       *     **  ** *  *  * * *  *   * *   *   *  *       *  *   ***        * ** *  * *  *****  *    * * * ** **** * ** **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7757] PF11236            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3037:Protein of unknown fu  -------------------------------------------------------------------- 111-1---------------------------11111----1111--1--------------1-1--111------------------112--1------11--112-1-------------------1------111-----1---------------------2-------------------------------------------------------------------------1------------------------------------------------------------111-----------------------------1--------------------------------------------------------------------------------------------1---------------1-11--------------------------------------------------------1-----------------------------1-------1-1---------------11---------------------------1-------111112--------1------------------1-1------1----------------1------------------1---11------------1---------1----------------11111111111111111------------1-11-1--------------------11----------1------1---1-2--------------1--1----------1---------1----11--1-----------2-----11-----------------------------------------------1-1 ---1--1-------12--1-11---1--------------------11-----------1-1--1-----------------------------2-1----231-11-2-4-1-111----1-----3------------1---1-1---3-----111---1-11----1-1--1--1-1----31111-1-------
 nction (DUF3037)                                                                                    *** *                           *****    ****  *              * *  ***                  ***  *      **  *** *                   *      ***     *                     *                                                                         *                                                            ***                             *                                                                                            *               * **                                                        *                             *       * *               **                           *       ******        *                  * *      *                *                  *   **            *         *                *****************            * ** *                    **          *      *   * *              *  *          *         *    **  *           *     **                                               * *    *  *       **  * **   *                    **           * *  *                             * *    *** ** * * * ***    *     *            *   * *   *     ***   * **    * *  *  * *    ***** *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7758] PF12162            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 STAT1_TAZ2bind:STAT1 TAZ2 bin  -------------------------------------------------------------------- --111-----------1---------------21-1--11-1-----1-----1----------1-1---------------------11-----------------------------------------------------2-------------------------1--------------------------------------------------------------------------------------------1---------------------------------------------1---------------------------1-------------------------------------1----------------------------------11112----------111122111------------1----------------1-------------------------------------111----------------------------1--------------1-----------------------1-----------------------11-1-----------------------------11--------------------------------------------------1111111111-111111111111111111--------------------------111111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1-----11-----------1------------------1----1-------------1---------------------------1-22---------2---2-113131-1111111231113-1-2221111111111111111132311-------1-------5---1------------1-1------
 ding domain                                                                                           ***           *               ** *  ** *     *     *          * *                     **                                                     *                         *                                                                                            *                                             *                           *                                     *                                  *****          *********            *                *                                     ***                            *              *                       *                       ** *                             **                                                  ********** ******************                          ******                                                                                                                                                                                      *     **           *                  *    *             *                           * **         *   * ****** ************* * *************************       *       *   *            * *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7759] PF11205            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            5                                                                                                                                                                                                                                                                                      
 DUF2987:Protein of unknown fu  -------------------------------------------------------------------- --------111-------------------------------------------1---------------------------------------11--------1----------------------1-------------------1---------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------1------------------111-----------------------------------------------------------1-------------------111--1-------------------------------------------------------------------------1-------------------------------------------------------------------------------1----1-------11-3--1-2111211111122111211112-------------------------------------------------------------------------------------------------------------------------------------------------------------1-1--1--11-11111111151111-111111111------------11----------------------1----------11------------1-- ---1---------------1---1---------------------------------------1----------1---------------------1----1--------1----2--1--1------------------11----11-----2----1-----2-------3---1-----------11-2--1-1--
 nction (DUF2987)                                                                                            ***                                           *                                       **        *                      *                   *                     *                                                                                                                                                                    *                     *                  ***                                                           *                   ***  *                                                                         *                                                                               *    *       ** *  * **********************                                                                                                                                                             * *  *  ** ************** *********            **                      *          **            *      *               *   *                                       *          *                     *    *        *    *  *  *                  **    **     *    *     *       *   *           ** *  * *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7760] PF12519            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3722:Protein of unknown fu  -------------------------------------------------------------------- -----------------11-1-----11111-----------------------1------------------------------------1-----------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------1---------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ -1------1--11221111111111132221121111111111111221122211111111111112112111111111111111121112111111111-21111--1221-2-11111-------1-2---11-1--1------21----2---------1-2----1-13---11-------312-2---2-----
 nction (DUF3722)                                                                                                     ** *     *****                       *                                    *                                                     *                                                                                                                             *                                 *                                                                                                                                                                                                                                                  *                                                                                                          *                                                                                      *                                                                                             *                                                                                *      *  ***************************************************************************************** *****  **** * *****       * *   ** *  *      **    *         * *    * **   **       *** *   *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7761] PF02267            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                                     
 Rib_hydrolayse:ADP-ribosyl cy  -------------------------------------------------------------------- ----------------------------------------------------------------1-----------------------------------1----------------------------------------------------------------------------------------------------------------------------11-1------------------------------------------------------------------------------------------------1--1------------------1--------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------11----1----------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------ --1-------1------1--11-----------1---1-1--------------1-----------------1--1---1----------------------1--1-111-2212-22342234422223-2-324322262223223312233234121114221------134----------1----1----1---
 clase                                                                                                                                                               *                                   *                                                                                                                            ** *                                                                                                *  *                  *                          *                                                                                                                                                                                                                                                         *                                                              **    *                                                                            *                                                                                                                                                   *       *      *  **           *   * *              *                 *  *   *                      *  * *** **** ************** * *********************************      ***          *    *    *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7762] PF08775            176                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 ParB:ParB family               -------------------------------------------------------------------- -----------------------------------------------------------------------------------------1---------------1--1-------------------------------------12------------------1--------------------------11111---1-1---1------------2-----------------------------------22-----11--11-----1--------------------------------------------------11-----1-----1--1---1-------------------------------------------------------------------------------------------------------------------------1------------------1------------------------------------------------------------------------1131------------------------------------------1----------1----1--------------------111--------1-------------------1----1-11----1------1---------------21----------------111--1-1222-12---111-11-1------------------------------------------------------11----------------------1-----11-----------------1--1--11-------1-----1-------------------------------------- -1---1--11--------111111111232111-21-111111-121----1-------1--1------11---2---1-------------------------21---1---1-1----11--22-1-3---1----1----------12--4----11--4151-----1--1---1---------11----1----
                                                                                                                                                                                              *               *  *                                     **                  *                          *****   * *   *            *                                   **     **  **     *                                                  **     *     *  *   *                                                                                                                         *                  *                                                                        ****                                          *          *    *                    ***        *                   *    * **    *      *               **                ***  * **** **   *** ** *                                                      **                      *     **                 *  *  **       *     *                                        *   *  **        *************** ** ****** ***    *       *  *      **   *   *                         **   *   * *    **  ** * *   *    *          **  *    **  ****     *  *   *         **    *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7763] PF08922            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1905:Domain of unknown fun  1---------1--1----------1-------------11111--1--------------1------- --------------1---------------------1222---1-41--2212----1--211----121------------------12-1--22-------1222-2----------------------------------1----1----1----------------------------------------------------1-------------1---1------1-------------------------------11--11------111-----------------------------------11---1111--1------1---1-1-------211----1--23-----------------2-111------------------------------1--11----1---11---1--------------2---------------------------------------------------1112--------------------1--------------------------1---------------------1-------------------------------1--1-------------------------------1----------------1----1------------------------------------------------------------1----1-----------------------------------------------------------------------1--1------1---1---------11-111111-----------------11111------------1122-----------------------------------------------1-- -----4-----1-----2---------------------------------1----------------------1--------------------1-----1--2--121-1-----1----1----------------------------------1-------1-------2------------2-1-11-------
 ction (DUF1905)                *         *  *          *             *****  *              *                      *                     ****   * **  ****    *  ***    ***                  ** *  **       **** *                                  *    *    *                                                    *             *   *      *                               **  **      ***                                   **   ****  *      *   * *       ***    *  **                 * ***                              *  **    *   **   *              *                                                   ****                    *                          *                     *                               *  *                               *                *    *                                                            *    *                                                                       *  *      *   *         ** ******                 *****            ****                                               *        *     *     *                                 *                      *                    *     *  *  *** *     *    *                                  *       *       *            * * **       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7764] PF09455            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Cas_DxTHG:CRISPR-associated (  --212113322324623132323------1-----11------------------11--2-2-32--- ----------1---1--------------------------------------------------------------------1-------1----------1--1--1-------------------------------11------1--------------------------------------11----------1-------2-----------------------------------------------------------1-----1--1---------------------------------------------1--1---------------------1-----1-------------12----------------------------------------------------------------------------------------------------------1--11--------1-------------------------------------------------------------------------------------------1-----1----------------1--1---------------1--1---------1---------------------1----1--------------1-------------------------------------------------------1-------------------------------------------------------------------------------------------------11111-------------------------11-----------------------------------------11--------- -1--1-1-1-3-------------1--11-----1---------------------------1-1---------111-------11---------1---1----1----1--11--------1-----11-1--13--------------1--23-2--122--31---11-1------1-----41---1----2---
 Cas) DxTHG family                *********************      *     **                  **  * * **              *   *                                                                    *       *          *  *  *                               **      *                                      **          *       *                                                           *     *  *                                             *  *                     *     *             **                                                                                                          *  **        *                                                                                           *     *                *  *               *  *         *                     *    *              *                                                       *                                                                                                 *****                         **                                         **           *  * * * *             *  **     *                           * *         ***       **         *   *    *    *  **        *     ** *  **              *  ** *  ***  **   ** *      *     **   *    *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7765] PF07315            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1462:Protein of unknown fu  --1--------------------------1---1---1---1--1-------1--1---1-------- ---------------------------------------------------------------------------------------------1-------------------------------------------------1-------2--------1-------1----------------------1111111111111111111111111111121111111111112222222222222211111----------1------------------------------------------------------------111----------------------------11-1-----------------------------------------------------------------------------------------------------------------------1------------------------------1--------------------------------------------------------------1-------------------1---------------------1-1111111----------------2---------------------------------------------1----------1----------1---------------------1----1-------------------------11111-----------------------------1----------------------1-----------------------------------------------------------------------------6-------------------- 11---1--------1------------------------------11--------------1---------1---------------------------------------1-1---1--1---211212-2-213-11------22-----1-----------4-------1----1--------1-1-1--------
 nction (DUF1462)                 *                          *   *   *   *  *       *  *   *                                                                                                      *                                                 *       *        *       *                      *************************************************************          *                                                            ***                            ** *                                                                                                                       *                              *                                                              *                   *                     * *******                *                                             *          *          *                     *    *                         *****                             *                      *                                                                             *                     **   *        *                              **              *         *                                       * *   *  *   ****** * *** **      **     *           *       *    *        * * *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7766] PF04090            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 RNA_pol_I_TF:RNA polymerase I  ----1------------------1-------------------------------------1------ ----------------------------------------------------------11--------------------------------------------------------------------------------------------------1-------1-1----------------------1---------1----1------------------------------------------------------1--------1------------------------------------------------------------1-----------------------11----------1----------------1----1-----------------------------1----1---------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------1-----------------------1-----------------------------------1-----------------------------------------------------------------------------------------------------1-------------------------------------1--------------------------------------------------------------------------------------1---------- 1111-2--1-1--1-121-12223112221111211122212111123111-12112---11312111-11-22111111111111211--121311112-21131---11-1----------------------1----1-1-2-----------11---11--1-1-2----1-----1-------4--1--1----
  specific initiation factor        *                  *                                     *                                                                 **                                                                                                  *       * *                      *         *    *                                                      *        *                                                            *                       **          *                *    *                             *    *                                                                                                                           *                                                                    *                       *                                   *                                                                                                     *                                     *                                                                                      *           **** *  * *  * *** ******************************** *****   ******** ** *****************  ********* *****   ** *                      *    * * *           **   **  * * *    *     *       *  *  *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7767] PF11086            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2878:Protein of unknown fu  ----1------------------1-------------------------1-----------------1 ----1------------------------------------1----1---------------------1--------1---------------1-----------------------------1------------11----------------------1----1-----1-----1------------------------------1------------------------------------------1-----------11-----------------------11111111111------------------------2----1--1---1---------------------------1------------------------1-------------------------1--------------------------------1--------------------------------------------------------------1----11--------21------2---1---------1------11----------1------11-1-------------1--1----------------------------1-------1-21111-111111111-111111--1-1---1--------------1---------------1---------------111----------------------------------------------2-----1111-1-11----------------------------1--111111111-111----------211-1111111111111111111111-1------------------------------------------------------------ -----------3-11-1------------------------------111-------1-----1---------1-----------1----111111-----1--------1----------------1-----21------1-----------2-1-----------1--------1------1---2----1-1----
 nction (DUF2878)                   *                  *                         *                 *     *                                    *    *                     *        *               *                             *            **                      *    *     *     *                              *                                          *           **                       ***********                        *    *  *   *                           *                        *                         *                                *                                                              *    **        **      *   *         *      **          *      ** *             *  *                            *       * ***** ********* ******  * *   *              *               *               ***                                              *     **** * **                            *  ********* ***          *** ********************** *                                                                        * ** *                              ***       *     *         *           *    ******     *        *                *     **      *           * *           *        *      *   *    * *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7768] PF02287            175                                                                                                                                                                                                                               1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Dehydratase_SU:Dehydratase sm  -----1-------------------------------------------------------------- -1-------------------1---3------1111-------1-------------2------1--1--------------------------------1-----1----------------------------1---------------9----------------------------------------------------------------11------111111---11111111111111-------1----------11---------------------------------------------1------------1--------1-1--11-111--------------------1------------------1-1----------------------11--1-1--1--------------1-----1--------11111111-----1-------------1-1----------------------------------------------------1---11----------1----------------------1-1------------------------------1----------------------------1-------------------------1--------------1--------------1-------1------1-----1232-----1111111111111112-------1--1--------------------------1---------------------------1------111----------------------------------------------------------------------------------------------------------- --12----2--------1----11-1-----------1111--1---2-----------------1----------1--1-1--11-----1-------------2-1-1---------------------------------------1---1---1-11----11------------------1---1-----2---
 all subunit                         *                                                                *                   *   *      ****       *             *      *  *                                *     *                            *               *                                                                **      ******   **************       *          **                                             *            *        * *  ** ***                    *                  * *                      **  * *  *              *     *        ********     *             * *                                                    *   **          *                      * *                              *                            *                         *              *              *       *      *     ****     ****************       *  *                          *                           *      ***                                                                                                              **    *        *    ** *           ****  *   *                 *          *  * *  **     *             * * *                                       *   *   * **    **                  *   *     *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7769] PF09314            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1972:Domain of unknown fun  -----1-----------1------------------------------------1-1----------- -11------------------------------------1-----11--11---------------1----------1--------1--1-2-2------11---11--------------------------1-----------2--1----------------411-----------------------------------------1----1------------------------------------------1------------1-1-11111111111111--1----1---21111211111111331112221----------------1----1--------1--------------1---------------------------------------1-1-2---1211--1----11---11-----1-------------------------------------------------------1---------------------------------1-----------1----------111-------------1----21------------1--1-2-------------------------11-------------1--1---1------11----1----------------------1---------------1--------------------1-1-1-----------------1---------------------------------------1----------------111----1------------------1---------112---------11----------------------------------1------------------1------1------------- -1---------1-----------------------------------1------------1------------11------------------2----1------1----------------11-----------21--------------1--1------11---1---1------------------1----1--1-
 ction (DUF1972)                     *           *                                    * *             **                                    *     **  **               *          *        *  * * *      **   **                          *           *  *                ***                                         *    *                                          *            * * **************  *    *   ***********************                *    *        *              *                                       * * *   ****  *    **   **     *                                                       *                                 *           *          ***             *    **            *  * *                         **             *  *   *      **    *                      *               *                    * * *                 *                                       *                ***    *                  *         ***         **                                  *                  *      *               *         *                                   *            *            **                  *    *      *                **           **              *  *      **   *   *                  *    *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7770] PF06755            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1219:Protein of unknown fu  -----1------------------------------------1------1------------------ --------------------------------------------------------------------1------------2--1---------------1-------------------------------------1------1------------------------------------------------------------------------------------1-----------------------1----------------------------------------------11--------------------------------------------------------------111--------------------------------------------------------------1-------------------------------------------15--11---------------------------------------------------------1----------------------------------------------------------------------------------------------1----------1---1-------1-------------------2-1-3326346231-2131414-33322-1321111-212212-------1-11-1--4-1111----1---1----121------------------------------------------------------------------------------------11----------------------------1--------------------------------------------- -----1----1-------------1---------------11----------------------------1-----------11---------------------1----2-----------------1------------------------2-1--2---1--21--1-2-----1-51-----------1-1111-
 nction (DUF1219)                    *                                    *      *                                                                                       *            *  *               *                                     *      *                                                                                    *                       *                                              **                                                              ***                                                              *                                           **  **                                                         *                                                                                              *          *   *       *                   * * ********** ******* ***** ******* ******       * ** *  * ****    *   *    ***                                                                                    **                            *                                                   *    *             *               **                            *           **                     *    *                 *                        * *  *   *  **  * *     * **           * **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7771] PF12580            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1                                                                                                                                                                  
 TPPII:Tripeptidyl peptidase I  --------111111---1-------------------------------------------------- ------------------------------------------------1------------------------------------------1-----------------------------------------------------------1-------------1-----------------------------------------------------1---------------------------------------1-------------------------------------------1----------------------1---------------1--------1--------1--------1----------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2----------------------------------------1 ----1-1-----111------------------1--2---------1-------------------------------1-1-----112-------111---1111-11151111121112111221223-1-22211111-11-11111211121121-352121131521112-11-----2121221111-12111
 I                                      ******   *                                                                                                   *                                          *                                                           *             *                                                     *                                       *                                           *                      *               *        *        *        *                                                                                                                                                          *                                                                                                                                                             *                                                                                                                                                                                              *                                        *     * *     ***                  *  *         *                               * *     ***       ***   **** *********************** * ******** ** ************** *************** **     ********** *****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7772] PF04278            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        2                                                                               1          
 Tic22:Tic22-like family        --------------1---1---1-1---------------------1--------------------- ----1----------------------------------------1-----------1---------------------------1-------------------1-----------------------1------11-------12312221111-----111131311-----11--1-1---------1--------------1--------------------------------------------------------------------------------------------1---111111111-----1---1-------------------------------------------------1----------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------8-1----------------------------------- 12-----13---------1----------------------------------1------1--1--------1----1---------------3--------------0-----12------1--------------1--1---1----------1----2--1--1-----1--512--1--223221-3259-11--
                                              *   *   * *                     *                          *                                        *           *                           *                   *                       *      **       ***********     *********     **  * *         *              *                                                                                            *   *********     *   *                                                 *                *                                                                                                                                                                                     *                                                                                                                                                                                                                                                                                                                  * *                                    **     **         *                                  *      *  *        *    *               *              *     **      *              *  *   *          *    *  *  *     *  ***  *  ****** **** **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7773] PF08664            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 YcbB:YcbB domain               --------------1---------------------1----------1----------1--------- ------------------------------------1-----1-----1---------------------------------------1-----11----------------------------------1--------------1----------------------------------------------123233212-12232221112122111-2---------31---------------1------1----1-----11----1------111------------------------------------------1-111211111-11------------------------------1--1---------------------------------1---------1-1--------------------1--------------------------------------------------------------------1-1-----------------------1---------------------------------------1--------------------------------1--------1------1------------------------1-------------1-------------------------------------------------------------1-----------------------------------------------1--------1---------------------------------------------------------1---------------12-----------------------3------1-----------------1----------- --1-1---1--1-1111----11-2-1------------1-11-------11-11----1---------1---1-------------1----1---------11---1--3-------------11----------------1-1-----1-11--1-3--1121-151--1----------1---11-11-1---1--
                                              *                     *          *          *                                              *     *     *                                       *     **                                  *              *                                              ********* ***************** *         **               *      *    *     **    *      ***                                          * ********* **                              *  *                                 *         * *                    *                                                                    * *                       *                                       *                                *        *      *                        *             *                                                             *                                               *        *                                                         *               **                       *      *                 *              * *   *  * ****    ** * *            * **       ** **    *         *   *             *    *         **   *  *             **                * *     * **  * *  **** ***  *          *   ** ** *   *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7774] PF07511            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1525:Protein of unknown fu  ------------------11111-1-----------------------------------1------- --1-11------------------1------111-1--------------------------1---------------------------12---1-------------------------------------------1------------------------1------1-------------------------------------1--------------------1---------------------------------------1-----------------------------------------------------2------------1-11--------------21-1---------1-----1----------------------------------------1-1-1---------------1-----------------------------------------------------------11------4---1-----------------111---1--1--1123-1-----1-1---1----------1-3-------------------------2------------1------------------------1-1----------------1-1---------1--2---------11-------------------1---------------1--1111--------1111--3---111---1--------1--------------1----1------11----11-------1---1--1-1-21-2-----111---------1-11-------1-----1-111----------2-------------------------------------------------------- ------1----1--1--------------1---------------------1---------------------------------------1------------1--272-1------1-----1------------1---1--1----------1-2-13--3-21---1-1--1111----1--1-----1---11-
 nction (DUF1525)                                 ***** *                                   *          * **                  *      *** *                          *                           **   *                                           *                        *      *                                     *                    *                                       *                                                     *            * **              ** *         *     *                                        * * *               *                                                           **      *   *                 ***   *  *  **** *     * *   *          * *                         *            *                        * *                * *         *  *         **                   *               *  ****        ****  *   ***   *        *              *    *      **    **       *   *  * * ** *     ***         * **       *     * ***          *                                                               *    *  *              *                     *                                       *            *  *** *      *     *            *   *  *          * * **  * **   * *  ****    *  *     *   ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7775] PF11193            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2812:Protein of unknown fu  -------------------1---1---------------------1----11---------------- --------------------------------------1---------------------------1-----------1121--------------------1-2-------------------------------------------------------------------------1-------------32222222212221221-11--223---11-21111--11-111111-11111111---------------22-------------1111---1--31111111111-11---132-11-111---111---2--2221122-2-31------31-1---11-22-1--------------1------------1-----------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------1---------------1----------------------1---------------------------------------1--------1--------------------------------------------------------------------1-------------------------------------------------------------------------------------------1--1---------------------------- ----1------------------------------------------2-----1-------1---------------------------------------1-----------------------------------------1--------------------1--------1-----------1-------------
 nction (DUF2812)                                  *   *                     *    **                                                       *                           *           ****                    * *                                                                         *             ***************** **  ***   ** *****  ** ****** ********               **             ****   *  *********** **   *** ** ***   ***   *  ******* * **      ** *   ** ** *              *            *                                                           *                                                                                                                                                           *                               *               *                      *                                       *        *                                                                    *                                                                                           *  *                                 *                                          *     *       *                                       *                                         *                    *        *           *             
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7776] PF05829            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                7                                  
 Adeno_PX:Adenovirus late L2 m  ------------------------1--------------1--------1------------------- ----------1-------------------------1-----3-----1----11-1-----------221---------------------------------1----------------------1---------------------1--------1------111---------------2--------------1------1------------------------------------------111----------------------1----1-------------------1-------------------------------------------------------------1---------------------------111---1-----1---------------1---------1---------1---------------------1-----------------------------------1-----11---------------11-------1-------11----------------------1-------------------------1--------------1---------------------------111-----------------1-------------------------------------------------------------------------------------1----------------------------------------------------------------2-------1-------1-------------1------------1-----1--1---------------------------------------------------------------- ------------------1------1---------1---------------1-----------------------------11-------1--11------------15---------------2-----------12--11----11----1-1----1----23-----------1-2--------1-1--------
 u core protein (Protein X)                             *              *        *                              *                         *     *     *    ** *           ***                                 *                      *                     *        *      ***               *              *      *                                          ***                      *    *                   *                                                             *                           ***   *     *               *         *         *                     *                                   *     **               **       *       **                      *                         *              *                           ***                 *                                                                                     *                                                                *       *       *             *            *     *  *                                                                                   *      *         *               *                             **       *  **            **               *           **  **    **    * *    *    **           * *        * *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7777] PF09839            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2066:Uncharacterized prote  ----------------------------1--1------------------------------------ --1-1----------11--------1--------------11------1-----1---------------------------1------------------------2-------------------------------1--1-1-------11-------1-1----1-----------------1---1---------------------------1---1--------------------------------------------------------------------------------------------------------------------------------1------------1----------------------11---1-------------------------11---------------2-1--------1---------1----211-----------------------------1-----------------------------------1-1------1-------------1------------------------1-------------1-------1-----------------------------11-311111111111111111111111111---2111-----------1----------1----------------------------1-----------1----------------------------111111-----11-1---------------------1---1111111111111111111---------11111111111111111111111111111--2------------------------------------------------------1-- --------1--1--1----------1--------1------1------------------------------------------1-----------------------2-1----1------12-----------------------------2-----1-1----------------1--1------------2-1-1
 in conserved in bacteria (DUF                              *  *                                       * *          **        *              **      *     *                           *                        *                               *  * *       **       * *    *                 *   *                           *   *                                                                                                                                *            *                      **   *                         **               * *        *         *    ***                             *                                   * *      *             *                        *             *       *                             ** ***************************   ****           *          *                            *           *                            ******     ** *                     *   *******************         *****************************  *                                                      *           *  *  *          *        *      *                                          *                       * *    *      **                             *     * *                *  *            * * *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7778] PF11626            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Rap1_C:Rap1 - C terminal doma  -----------------------------1----------------------------------1--- --------------------------------------1--------------1---1--1--1-----------11-----------11----------1---2-----------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1----------------------1-------------1------------------------------------------------------------------------------------------------------------------1-1------------------------1-------------1---------------------------------------------------------------- ---1-1-----1-1111112222212211-32211112322332222221-1-111--11111-1111111113-11-111----1--1--11----------------1-11-1221-1111111-211-1-1-21-111-11-11211-1-111111-----1--111-1-------------11--2---1-1---
 in                                                          *                                  *                                          *              *   *  *  *           **           **          *   *                                                                                                                             *                                                                                                                                                                                                     **              *                                                                                                                                                                                      *                             *                      *             *                                                                                                                  * *                        *             *                                                                    * *     * **************** ******************** * ***  ***** ********** ** ***    *  *  **                * ** **** ******* *** * * ** *** ** ***** * ******     *  *** *             **  *   * *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7779] PF07636            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 PSRT:PSRT                      -----------------------------1----------------1--------------------- ---------------1--------1------1-111-----11-------------1-------1-----------------1------------------------------------------1-----------11-----1--1----------------1---------------------1---1------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------1-912---------------------11-111111-------1-1---------11-----1--------1------------------------------------------------------------------1-1----------1--------------------------------------------1------------------------------12-------------------------------------------------------------------------1----------2--------------------------------2-------------------1------111--------------1------------------------------------1-------------1---1-------------------1-----------1-1-----------------------1---------------------------------------- --------21--11111-111-1-1--------1--1--------111-11112---1-1-------1-1---------------------31--------11-1---3-1-12--22113---21-313-1-11-12--3121---12-1---1-11-1-1-1--------1--11---1---11221-12-2---11
                                                             *                *                                     *        *      * ***     **             *       *                 *                                          *           **     *  *                *                     *   *                                                                                                                                                                  *                  * ***                     ** ******       * *         **     *        *                                                                  * *          *                                            *                              **                                                                         *          *                                *                   *      ***              *                                    *             *   *                   *           * *                       *                                                 **  ***** *** * *        *  *        *** *****   * *       * *                     **        ** *   * * **  *****   ** *** * ** **  ****   ** *   * ** * * *        *  **   *   ***** ** *   **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7780] PF11392            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2877:Protein of unknown fu  -------------------------------1------------------------------------ ---------------------------------------------1----------1-----1---------------------------------------------------------------------------------1-----------------------------------------------------1-----------111-------1---------1----------------1----2------------------------------------111-11----------------------------31---------1-1---------------------------1---------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------1-1------2------2------------------------------------------------------------------------------1------------------------------------1------2223233322-22223322222323313321-1----11-111-1111111111-1111-12--------------------------------------------11-------------------------------------------11-11-------------------------------------------------------------------------------- ----1211-2-------1-111------1--------1111---1-11--------------11-----1--------------------1------------1----1----1-------1-----1---------------1------------------------1-------12-2------1-1---21-1---
 nction (DUF2877)                                              *                                                                                  *          *     *                                                                                 *                                                     *           ***       *         *                *    *                                    *** **                            **         * *                           *                                                         **                                                                                                                    * *      *      *                                                                              *                                    *      ********** ******************** *    ** *** ********** **** **                                            **                                           ** **                                                                                     **** *       * ***      *        ****   * **              **     *                    *            *    *    *       *     *               *                        *       ** *      * *   ** *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7781] PF06942            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 GlpM:GlpM protein              ---------------------------------------------------------1---------- ----1-----------------------------------------------------------------------------------1-----------1---1----------------------------1---------1-----------------1--------1-----------1---------111-------------------------------------1------------------------------22-------------------------------------------------------------------------1--------2---1-------------12-------------------11---1--11----------------------1-------------------------------------------------------------------------------------------------------1----------1----------------------1----------------111-------------1---------------------------------1-------1----------------------------------------11111111111111111-111111111111111111111111---1111-11111111111-1111111--111111111111---------------1-----1----------11111111-1---11111111-111--11---------------111112-122----1--------------------------------------------------------------------- ----------1-----------------1-----------------------1-------------------------11--1--------1---1-----1-11---11----11---1----1--------------------------1------------------------------------111-----2--
                                                                                         *               *                                                                                   *           *   *                            *         *                 *        *           *         ***                                     *                              **                                                                         *        *   *             **                   **   *  **                      *                                                                                                       *          *                      *                ***             *                                 *       *                                        ***************** ************************   **** *********** *******  ************               *     *          ******** *   ******** ***  **               ****** ***    *                                                                                *                 *                       *                         **  *        *   *     * **   **    **   *    *                          *                                    ***     *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7782] PF05463            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Sclerostin:Sclerostin (SOST)   -----------------------------------------------------------1-------- -------1----------------------------------------------------1---1--------------------------------------------------------------------------------------1--------------1--------------------------------------------------------------------1----------1--------------------------------------------------------------------------------------------------------------------------1-------------------------------------------1----------------------------------------------------------------------------------------------------------------------------1-----1---------------------------1---------1-----------------------------------------------------------------------------------------1-------11--------1---------1-----------1-----------------------------------------------------------1-------------------------------------------------------------------------1-------------------------------------------------------------------- 1-----------22--------------------2--------1121-------------------------------1--------1--1--1-1-------------113412513--2223221236-2-423332322223332-122-442321-1--1335---3-112------1---3-------1-1-1-
                                                                                           *                *                                                    *   *                                                                                      *              *                                                                    *          *                                                                                                                          *                                           *                                                                                                                            *     *                           *         *                                                                                         *       **        *         *           *                                                           *                                                                         *                                                                     *           **                    *        ****                               *        *  *  * *             *********  ********** * *************** *** ****** *  ****   * ***      *   *       * * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7783] PF05420            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 BCSC_C:Cellulose synthase ope  -------------------------------------------------------------------- -1----------1------------1--------------------------1------------------------------21-1------2----------1---------------------1------------------1----------------11--111------------------------------------------------1-------------1---------------------------------------------------------------------------------------------------1-------------------------------------------1---------12-----1---------------------1--------------------1--------------------------------------------------------------11----1111111111-11111111-1121-1-1-111-1--------1-------11-----------1-----------------1-1------1-----1-------------------------------1-----1---111---------------------------11112211111111111-111111111111-11111122211--214111111111-1-1111--------1------------------------------------------------------2--------1-121-11-------------111-------211--212----------------------------1-------------------------------------1-- -----1---------------------------------------1-1----------------------------1-12---------11-----------------1--------------------------------------------------------1-------------------1-----------1-
 ron protein C C-terminus (BCS                                                                        *          *            *                          *                              ** *      *          *                     *                  *                **  ***                                                *             *                                                                                                   *                                           *         **     *                     *                    *                                                              **    ********** ******** **** * * *** *        *       **           *                 * *      *     *                               *     *   ***                           ***************** ************ ***********  ************ * ****        *                                                      *        * *** **             ***       ***  ***                            *                                     *        *                                       * *                            * **         **                 *                                                        *                   *           * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7784] PF06764            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1223:Protein of unknown fu  -------------------------------------------------------------------- -11----------------------------------------1--------------------------------------------------22----2---1--------------------------------1-------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1-------------------------------------------------2111-----111221111121111111111111---2--1-2121-111111112121121111111111111---------1------------------------------------1----------------1111--21111111-----------1-------1-1--11----1-----------------------------------------------------------------------------------11-------111-1--1--1-----------------------------------------------------------1--------------1------------------------------------1----------------------------11--1----------------------------------1----------------------------------1--------------------------------------11- ------1-------1----11---1--111-----------------111--11---1-------11-1-------1-------------------------1--1--411---------------------------------1-1----1-------------1-----11-1-11-----1-2134-31--1----
 nction (DUF1223)                                                                                     **                                        *                                                  **    *   *                                *                                                                                                                         *                                                                 *                                                 ****     ************************   *  * **** ***************************         *                                    *                ****  ********           *       * *  **    *                                                                                   **       *** *  *  *                                                           *              *                                    *                            **  *                                  *                                  *                                      **        *       *    **   *  ***                 ***  **   *       ** *       *                         *  *  ***                                 * *    *             *     ** * **     * **** **  *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7785] PF04836            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 IFRD_C:Interferon-related pro  -------------------------------------------------------------------- --1---------------------------------1111----------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------2-1----------------------------------------------------------------------------------1-------------------------------------------------------------------1-----------------------------------1----------1-------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------1-----11-------------------1----------------11-25624232312232212227-3-213222222221122223112211251212212-12111121-11-----113123-52112-1--
 tein conserved region                                                                                 *                                 ****                                                                                                                            *                                                                                                                                                                                                                 *                                                            * *                                                                                  *                                                                   *                                   *          *                                                                                                                                                       *                                                                                                                                                                                               *     **                   *                ** ******************** * ********************************* ******** **     ****** ***** *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7786] PF03543            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                                                                                                                                                                                                                                               1                                                                     
 Peptidase_C58:Yersinia/Haemop  -------------------------------------------------------------------- --------------------------------------11----------------------------------------1----------------------------2--------1--------------------------1-----------------------------------------------------1------------------1----------------------------------1--------------------1-1------------------------------------------------------------------------------11-----------------------------2----------------------1---1-------------1----1-----------------------------------------1-----------------1------------------------1---1-1-1-2--1-----1--2------1------1-1---------------1--------------------------1-----------------------------------1-----------------------------------------1------------------2------------------44---------------------------211111-11-1---3------2322--5--------2------12------------------11------23--------------------1------------------------------------------------------------------------------ -----1--2--1--1-----11--------1-----1------111-21111-1---1--2--1-------1-----------1-1------------------1-----1---112-------1----2-3-115--1---11---1-----1------11-1---1--1-1---12-------2--1----11----
 hilus virulence surface antig                                                                                                             **                                        *                            *        *                          *                                                     *                  *                                  *                    * *                                                                              **                             *                      *   *             *    *                                         *                 *                        *   * * * *  *     *  *      *      * *               *                          *                                   *                                         *                  *                  **                           ****** ** *   *      ****  *        *      **                  **      **                    *                                                                                    *  *  *  *     **        *     *      *** ***** *   *  *  *       *           * *                  *     *   ***       *    * * ***  *   **   *     *      ** *   *  * *   **       *  *    **    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7787] PF05581            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 MCP_N:Vibrio chemotaxis prote  -------------------------------------------------------------------- ---------------------------------------------1------------------------------------------------------2-----1--------------------1-----1---------------------------------------------1-------------------------------------4-------------1-11111111111111-------------------------------------1---------------1----------------------------------1---11--------------21--------1----1------------------------------------------1-----------------------------------------------1----------1-------------------------------1----1----------1----------------------1-----------1--------------1---------1---1-1--1---1----------1------------------1------------1-1--1---------1---111-----1-1----------------------------------------------1---------------------------------------------------------1-1-------------------1--11---222-1332211111-11----------11124334311133----------------------------------------------------------------1--------- -11-11-------------------------------11--11------1--1-----------------1-1--1-----111-1----1--11--1-1-1---1---1--2----1-11-1--111------11------1--11-------21--1-------1---1-------1------1--2---1--1---
 in N terminus                                                                                                                                    *                                                      *     *                    *     *                                             *                                     *             * **************                                     *               *                                  *   **              **        *    *                                          *                                               *          *                               *    *          *                      *           *              *         *   * *  *   *          *                  *            * *  *         *   ***     * *                                              *                                                         * *                   *  **   *** ********** **          **************                                                                *           ** **                               **  **      *  *                 * *  *     *** *    *  **  * * *   *   *  *    * ** *  ***      **      *  **       **  *       *   *       *      *  *   *  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7788] PF10425            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 SdrG_C_C:C-terminus of bacter  -------------------------------------------------------------------- -------------------------------------------------------------------------------------1----1---------2--1-----------------------------------------------------------------------------------------11111--111-11---------1-----------------777577467777771111-1------------11-----------11121-3--------------------12211-1------------1-1------------11--------4----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1------------------------------------1-------------------------1-----1----------------------------------------------------1-1--1---------1-1------1-------------1-----------------------------------------------------------------------1----------------------------------------------------------------111111--------------------------------------1----------- ----1-----------------------------------------------------------1----1--------1-1--------------1-------------1------------------------------------------------------12-11-1----------------------1-----
 ial fibrinogen-binding adhesi                                                                                                                                                            *    *         *  *                                                                                         *****  *** **         *                 ****************** *            **           ***** *                    ***** *            * *            **        *                                                                                                                                                                                                          *         *                                    *                         *     *                                                    * *  *         * *      *             *                                                                       *                                                                ******                                      *                *                                                           *    *        * *              *             *                                                      ** ** *                      *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7789] PF08890            175                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 XkdN:Phage XkdN-like protein   -------------------------------------------------------------------- -------------------------------------------------------------------------------------------1----------1--------------------------------------------------------------------------1--------------------------------1-11------3--11-----42----------------------------21-------------------------------------------------------------2--4-3-13--1111332----211---11--121------1--1------------1----------1-----------------------------------1-------------------------------------------------------------------------------------------------------------------------1-------11---------------------------------------------1-------1--------------------1---------------------------------------------------------------------------------------------------1------------------------111111---1----------------1---------------------1--1111-------------1----------------------------------------------------------------------------------1----1 1---1-----121-----1---------1-----1--------2-------------------1--------------------1------1-------1-11----1--1--1--12-3122111-2-4-1-2232-122111-131-22---2----1-1111-----114---------1--121----1-11---
                                                                                                                                                                                                *          *                                                                          *                                * **      *  **     **                            **                                                             *  * * **  *******    ***   **  ***      *  *            *          *                                   *                                                                                                                         *       **                                             *       *                    *                                                                                                   *                        ******   *                *                     *  ****             *                                                                                  *    * *   *     ***     *         *     *        *                   *                    *      *       * **    *  *  *  ** ******* * * * **** ****** *** **   *    * ****     ***         *  ***    * **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7790] PF06923            174                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 GutM:Glucitol operon activato  ---1----------------1--1----1------1-------------------------------- ----------1--------------1------------11-----------------------1-----------------------------------------1------------------------------11-----------11---------------------------------------------------------21111-----------111111-----------------1----1---12-----12--11-2--------1--111-11------------1----1---------------1----21111111111-2--------------------------11----------------1--1--------------------1----------1--------------1--1--------1--------------------------------1-------------------------------1-----------1------------------------11---------------------1---------------1------------------1-----1----------1-------12--1------------------1------------------1------1111111111-11111-111111111111--11-----11111111111111112-111111--1--------------------1-----------1-1------1111------------------------------------------11111--------------------1---------------------------------------------------------- -----------1---------------------------------111----------------------------------------------1--------------2----1---------------------------------------------------1-----2------1------1--1----12-2-
 r protein (GutM)                  *                *  *    *      *                                           *              *            **                       *                                         *                              **           **                                                         *****           ******                 *    *   **     **  ** *        *  *** **            *    *               *    *********** *                          **                *  *                    *          *              *  *        *                                *                               *           *                        **                     *               *                  *     *          *       **  *                  *                  *      ********** ***** ************  **     ***************** ******  *                    *           * *      ****                                          *****                    *                                                                      *                                 ***                                              *              *    *                                                   *     *      *      *  *    ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7791] PF10858            174                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2659:Protein of unknown fu  ----1-------------------------------1------------------------------- ----------------------------------------------------1-----1----1----1------------1-----1-----------------------------------------------------------1--------------------1-11--1--------1-------1111111112-1112-1------11-----11--------1------1-12-1--1---1-----------------------------------------1112112--------1-1-------------2-11-1-1112-1-----1----1----------1----------1---------------------------------------------------1--------------1---------------------11---------------111111111111111-----1---------------------------------------11--------------------------------------1-------1------1----------------------------------------------------------------------------------2----------------------1--------------1----------------------------------------------------------------------------------------1------------------------1------------------------------1--1--1111------------1--------------------111-1------------ --1111------12---1-1--1---1---11--------------1----11----------12-1---11-1-------111---1-------------2------2---21---------------2--1-------------------------1-12111-1-1211--------------322----2--1--
 nction (DUF2659)                   *                               *                                                                                    *     *    *    *            *     *                                                           *                    * **  *        *       ********** **** *      **     **        *      * ** *  *   *                                         *******        * *             * ** * **** *     *    *          *          *                                                   *              *                     **               ***************     *                                       **                                      *       *      *                                                                                  *                      *              *                                                                                        *                        *                              *  *  ****            *                    *** *               ****      **   * *  *   *   **              *    **          ** *   ** *       ***   *             *      *   **               *  *                         * ***** * ****              ***    *  *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7792] PF02312            174                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CBF_beta:Core binding factor   ----1-------------1-----------------------------1--1---------------- -------1-----------------------------------------------------------------------------------13------------1---------------------1--------11------------1----------------------1------------1----------------------------1--------111121---------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------1---------------------------------------------------------------------------1---------1--------1------------------------1--------111-1---------------------------------11---1111111111111111----------1--------------------------1--------------------------1-------------------------------------------------1---1-------11----1-----------------------------------------------1- -1---1----------------1--------------1111----1---------------------------------1---------------11----1--------4312-111122112541122-2-213112-2111-111111111131312113111121141221------11-----1----------
 beta subunit                       *             *                             *  *                        *                                                                                   **            *                     *        **            *                      *            *                            *        ******                                             *                                                                                                                                                                                                                                         *                                   *                                                                           *         *        *                        *        *** *                                 **   ****************          *                          *                          *                                                 *   *       **    *                                               *   *   *                *              ****    *                                 *               **    *        **** *************** * ****** **** ******************************      **     *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[7793] PF08329            174                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 ChitinaseA_N:Chitinase A, N-t  ------1--------11---------------------1-----------1----------------- ---------------------------------------------3--11-------1-----------1----------------------------------11------------------------------------------------------1-----1----------------11---------------1-111-1--1----11--------1----1-67--------------------------------------------------------------------------------1-------------444444414--------------------------------1---------------1--1-------------------------------------------------------------------------------------------------------------------------1--------1--------1--------------------------------------2-------------------------------1------------------------------1----2------1111111111-1-14-16-------------1------------------------------------1-----------------------1------------------------1-----------1---------------------------------------------------------11-1111111111--2---2------------------------------------------------------------------- -----------------1-1----1-----------------1--------1----------------------1---1------------------------11-----1-----1---------------------------------------1--11--23121--3------1--11---1341----121---
 erminal domain                       *        **                     *           *                                                               *  **       *           *                                  **                                                      *     *                **               * *** *  *    **        *    * **                                                                                *             *******