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Ranking of HM:PFM:REP : from 8101 to 8200

                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8101] PF07878            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1662:Protein of unknown fu  ------------1---------1--------------------------------------------- -------------------------1------------------------------------1-----111-----------------------11-----------------------1111--1-------------------2---1------433331--------242222242223--------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------1-------------------11-----------------------------------------------------------1-----------------------------1111------------111-1----------------------------------------------------------------1--------------------------------------1-----------1111--1-----1-1------------------1--------------------------------------1---------------------------1---1------------------------21---------------------1--------1---------1------------------------------------------------------------------------------------------4----------- --111-2----21----1--1-----1---------1---------1----1----1--1------1------1-------111------1--------1-----1--31--21-------------2-6-1-4-1------------1-----------1--1--31-11---1-----11-----11-----111--
 nction (DUF1662)                           *         *                                                                       *                                    *     ***                       **                       ****  *                   *   *      ******        ************                                                                                                                                                        *                                                           *                   **                                                           *                             ****            *** *                                                                *                                      *           ****  *     * *                  *                                      *                           *   *                        **                     *        *         *                                                                                          *              *** *    **    *  *     *         *         *    *    *  *      *      *       ***      *        *     *  **  **             * * * * *            *           *  *  ** **   *     **     **     ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8102] PF04346            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 EutH:Ethanolamine utilisation  ------------1----1-------------1------------------1----------------- -----------------11-1---1-111111----1---11-------------------------1--1--------11------------1---------1------------------------------------------1------------1-------1-2----------------------------1-1----2-------1------21--1111111----------------1----1---111--------------1----------1---------------------------1----------12-1-------1-1-3--122112---------------------1-11-------------11-----------------------------------------------------1--------------------1------------------------------------------------------------------------------------1-------------------------1--------------1-----------1---------------------------------1----------------------1---------------1------1111111111-1111111111111111111111-----11111111111111111-1----1-----------------------------------------------------------11-1-2-----1--------------------------1-------------------1-------------------------------------------------------- -----------------1------1------------------1--2---1------------------1---------------1------------------------1--1-1----1----------1--------------1-----------------1----1--1---------------1-----1----
  protein, EutH                             *    *             *                  *                                   ** *   * ******    *   **                         *  *        **            *         *                                          *            *       * *                            * *    *       *      **  *******                *    *   ***              *          *                           *          ** *       * * *  ******                     * **             **                                                     *                    *                                                                                    *                         *              *           *                                 *                      *               *      ********** **********************     ***************** *    *                                                           ** * *     *                          *                   *                                                                          *      *                  *  *   *                  *               *                        *  * *    *          *              *                 *    *  *               *     *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8103] PF04373            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF511:Protein of unknown fun  --------------1----------------------1---1-------------------------- ------------------------------------------------------------------------------------1----------------------------------------11--1--------1----------------------------------1-------------1--------------------------------1----1-------------------------------------------1---------------------------------------------------------------------------------------1-1--------------------11-1---------1-1---------------------------------------------------------------------------------112-11---23-----------1------------------------------------1------2------1--------------1-----------1-1------------------1------11122--13-11131-2----1----1-------1------1-2------------1----------------------------------------------------2----------------------------------------------------11-----------------1----------1--1------------------------------------------1-------1111--11--------------1----------------------------1----------11 -----1------11---------------------------11--------1--------1--1----1-1-----1--1----1----------------4--1---11-111---1---13-121311-1-126-------2-121--111--4121---1-----1----1------------33--11---2---
 ction (DUF511)                               *                      *   *                                                                                                               *                                        **  *        *                                  *             *                                *    *                                           *                                                                                       * *                    ** *         * *                                                                                 *** **   **           *                                    *      *      *              *           * *                  *      *****  ** ***** *    *    *       *      * *            *                                                    *                                                    **                 *          *  *                                          *       ****  **              *                            *          **      *      **                           **        *        *  *    * *     *  *    *                *  *   ** ***   *   ** ****** * ***       * ***  ***  ****   *     *    *            **  **   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8104] PF12616            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3775:Protein of unknown fu  ---------------1---------11----------------------11----------------- ---------------------1----------------11-------1------------------11-1--------------------------------------------------------------------------------------1----------2--1-------------------1---------------------------1---1--11----------------------------------------------------11-------------------------------------------------------------------------------------------------1-----1-122--2122121-111111111-22122321211-----------------1112----112--------1------1--------------------------------1------------------------2------1122-------------------------------1-------------------------------1--1------------------------------------1--1------------------------111--------------11--------------1-1--------------1--1------------------------------------------11111---1---------------------------------------1----------------------1------------------------------------------------------------------------------------ ---------1----1------11111-2--------1-1-------1---1----------------1---------------------4-1---1--11-1--1---5-11---21-------1-------------1-----1--1-----11-1---------11--1------------11---------5----
 nction (DUF3775)                              *         **                      **                                       *                **       *                  ** *                                                                                      *          *  *                   *                           *   *  **                                                    **                                                                                                 *     * ***  ******* ********* ***********                 ****    ***        *      *                                *                        *      ****                               *                               *  *                                    *  *                        ***              **              * *              *  *                                          *****   *                                       *                      *                                                                                              *    *      ***** *        * *       *   *                *                     * *   *  ** *  *   * **   **       *             *     *  *     ** *         **  *            **         *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8105] PF02983            162                                                                                                                                             1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
 Pro_Al_protease:Alpha-lytic p  ------------------------1-1----1-----------------------------------1 --1-3-1----1-----11-1---1-11111--111-----1-11--1--1------1--221-5326901----1-------------------------------1-------------------------------------1----------------------2-----1---------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------1-21-11-11----11--11----2-----------------------------1--------------------------------------21----------------1-11----------1------1-------1------------------------------------------1-------1---------------------------------11---------------11---------------------------------------1---------1------------1----------------------------------------------------------------------------1-------------1---------------------------------------------------------------------------------------------------1-------1-- -----------1--1--11111----1------1------------1-1-------21---1---------------------------12---1-------------2-1----------1-1--1-------------------------------------1-1-1-1------112--1---134---1--12--
 rotease prodomain                                      * *    *                                   *   * * *    *     ** *   * *****  ***     * **  *  *      *  *** *******    *                               *                                     *                      *     *               *                                                                                                                                                               *                                                        * ** ** **    **  **    *                             *                                      **                * **          *      *       *                                          *       *                                 **               **                                       *         *            *                                                                            *             *                                                                                                   *       *              *  *  *****    *      *            * *       **   *                           **   *             * *          * *  *                                     * * * *      ***  *   ***   *  **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8106] PF11363            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3164:Protein of unknown fu  ------------------------1------------------------------------------- --1-------------------------------------------------------------------------------------------------1-------1-------------------------------------------------------------------------------1-----------------1--1------------2-111-1-----------------------1-------------------1--1-1----------------------------------------------------1----1---1-----------1-------------------------------4--1----1--------------------------------2--------11-------2-----11111111------1------111----------------------------1--1---2--1---------------1----------2-2----------1-1--11--1111-------1---1---------1--1--------------1------------11111-1---------1-1-1--1---11-------1-2-----------1-------------2--12--111--121-1-11--11222221---1----------------------------2------------1------------------------2------1----------1----------------1-----------------2--2--------------------------1---------------------------------------------------- -1---1--1----------------------1-1---------------2------------------1----1-----1-----2---------------2-2------1--------------------------------------1--11---2--17---1---1-11------------1-------------
 nction (DUF3164)                                       *                                              *                                                                                                 *       *                                                                               *                 *  *            * *** *                       *                   *  * *                                                    *    *   *           *                               *  *    *                                *        **       *     ********      *      ***                            *  *   *  *               *          * *          * *  **  ****       *   *         *  *              *            ***** *         * * *  *   **       * *           *             *  **  ***  *** * **  ********   *                            *            *                        *      *          *                *                 *  *                          *                                                      *   *  *                      * *               *                  *    *     *     *               * *      *                                      *  **   *  **   *   * **            *             
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8107] PF08982            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1857:Domain of unknown fun  ----------------------------1-----1--------1------------------------ ----------------------111-----------------------------------------------------------------1-----------------1---------------------11--------------------------------------------------1--------------1------------------------------------------------------------------------------------------------------------1-----------------------------------------------1-----1--------------1--1------------------------------------------1------11-------1-------------------------------11---------------------------------1111111111-11111111-11111111--111-1-11------11------1----------111---------------313---1---1-------------------------------14---------------------------------------------------11--------1---------1---------------------------------------------------------------------1-----------------------------1111-----------------------------------1---------------------------------------------------------------1----------- ----7----1------121-1211--1-----1----333322-1--1-111-1--111----------1-11--------11------11-12-1----1------------1---------1-------1-11-----1-------1-----11-----------1-21-1-11---1-----1---1-----1---
 ction (DUF1857)                                            *     *        *                                               ***                                                                 *                 *                     **                                                  *              *                                                                                                            *                                               *     *              *  *                                          *      **       *                               **                                 ********** ******** ********  *** * **      **      *          ***               ***   *   *                               **                                                   **        *         *                                                                     *                             ****                                   *                                                               *                *    *      *** ****  *     *    ****** *  * *** *  ***          * **        **      ** ** *    *            *         *       * **     *       *     **           * ** * **   *     *   *     *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8108] PF05009            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 EBV-NA3:Epstein-Barr virus nu  ------------------------------1------------------------------------- -------------------------------------1----------------------------------------------------------------------1-----------------------------------------1-------------1------------1---------------------------1--------------------------------------------------------------------------------------------------------------------1----1----1--------------------------------------------------------------------------1-----------------------1-----------------------------------------------------------------------------------11----------1----------------1-------------------------1-------------------------------------------------------------------------------------------------------------11--------1---------1-------------12------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------ -1---21--113---22221----1-131111-1---1112112111-2-111--1----1---1--1--1--1-1111-1-1-12------22-1---2----11---2-------2--1--111-214-1-11--1-----1---1----12-111----1133-1--2341-----2-1----12-13-1-44-11
 clear antigen 3 (EBNA-3)                                     *                                                                           *                                                                      *                                         *             *            *                           *                                                                                                                    *    *    *                                                                          *                       *                                                                                   **          *                *                         *                                                                                                             **        *         *             **                                                      *                                                                                                                                                  *   **  ***   *****    * ****** *   ********** * ***  *    *   *  *  *  * **** * * **      ** *   *    **   *       *  *  *** *** * **  *     *   *    ** ***    **** *  ****     * *    ** ** * ** **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8109] PF06988            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 NifT:NifT/FixU protein         ------------------------------1--------------------------1---------- --------------------------------1-----------------------1-------------1----------------1--------------------1-------------------------------------11211-11------------2122---------------------------------11-----1-----------1----------------------------------1------------1-------------------------------------------------------------1--1--------------------1------------------1--------11122---11121--------------2--1---1------111-111111------1111------------11--111--------------------------1----1--1-------------------2-------211--------1-----1------1--------------1--11-----------------------------------------------------1---11--1------------------------------------------1----------------------------------12111-1----------------------------11111111111-1-----------1---------------1------1------2--------------2--1----------------------------------------1------------------------1------111-------------------1-1- -1--11----1-----------1------1-------1-1111-------1------1--------1-----------------------------1----1------2-1--1--------11---------------------------------------1121----24------3--------121-1------
                                                              *                          *                                           *                       *             *                *                    *                                     ***** **            ****                                 **     *           *                                  *            *                                                             *  *                    *                  *        *****   *****              *  *   *      *** ******      ****            **  ***                          *    *  *                   *       ***        *     *      *              *  **                                                     *   **  *                                          *                                  ***** *                            *********** *           *               *      *      *              *  *                                        *                        *      ***                   * *   *  **    *           *      *       * ****       *      *        *                             *    *      * *  *        **                                       ****    **      *        *** *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8110] PF10627            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CsgE:Curli assembly protein C  ---------------------------------1--------------------------1----1-- -------------------------------------------------------------------------------------------1--------1-----1---------------------2---1----------------------------------------------------------1----------------------------------------1-----------------------1------------------------1-----------------------------------------1--------------2---------------------------------------------------1----------------------------------------------------------------------------1-----1--------1----1-----------1-------------------------1------------------------------2-----------------------------------1----------------------2----------------1---1-1-1111111-1111111-1-1-------------1----1-1111111111-1111111111111111111--------1-111111111111111-111211-------------------------------1-----------------------------1-1-1--11111-------------112---------------------1---------------------------------1----------------------------2 --112---1--1----------1--------------------1-------1-----------1----------------1--1-------1--1-1-1--21-21---2-----1-1------1--2-1--------------------1-2-------------1--1--1------1-1------5----------
 sgE                                                             *                          *    *                                                                                              *        *     *                     *   *                                                          *                                        *                       *                        *                                         *              *                                                   *                                                                            *     *        *    *           *                         *                              *                                   *                      *                *   * * ******* ******* * *             *    * ********** *******************        * *************** ******                               *                             * * *  *****             ***                     *                                 *                            *   ***   *  *          *                    *       *           *                *  *       *  * * *  ** **   *     * *      *  * *                    * *             *  *  *      * *      *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8111] PF12470            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 SUFU_C:Suppressor of Fused Gl  -----------------------------------------1-------------------------- --2-----------------------------------1----1----------------------1--------------------------------------------------------1-----------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------21----------1------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------1---1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1------------------------------------------------------------- ---1-1----------------11-1--1-------1--------111112111----11------------------1----1-1-----1-11---------1--1-141112221211112522314-1-224-1211111111222112122231433-632311121-2--1----------------1-11--
 i/Ci N terminal binding domai                                           *                             *                                   *    *                      *                                                        *                                                                                         *                                                                                                                             **          *                                                                        *                                                                                                 *                                                                                        *   *                                                                                                                                                                                                                                           * *                                                                 * *                ** *  *       *        *********    **                  *    * *     * **         *  * ********************* * *** ************************* ********* *  *                * **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8112] PF10272            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Tmpp129:Putative transmembran  ---------------------------------------------------25--------------- -1---------------------------------------1--------------------1----------------------1-----1---------1----1----------------------------------1---1-----1-----------------------------------------------------1------1-------11----------------------------1--------------------1------1------------------------------------11----1---1------------1------------------------------------------------------1-------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------11----------------------------------------------------1-----------------------1----1--------------------------------------------------------1--1------------------------------------------------------------------------11111-----------------------------------12--------1------------------------11-----------------------------1--------1----------- ----1-1-1--1-----------------1--------------------1---1----1--1-11--2-------1-------1--------2------1-12---1-14111-32211--1111-218-2-213-12111111-22--1--1-11111121411312121231--1------------1----1---
 e protein precursor                                                               **                 *                                       *                    *                      *     *         *    *                                  *   *     *                                                     *      *       **                            *                    *      *                                    **    *   *            *                                                      *                                                                                                       *                                                                          **                                                    *                       *    *                                                        *  *                                                                        *****                                   **        *                        **                             *        *                * * *  *                 *                    *   *    *  * **  *       *       *        *      * **   * ***** *****  **** *** * *** ******** **  *  * ********************  *            *    *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8113] PF02288            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Dehydratase_MU:Dehydratase me  -------------------------------------------------------------------- ----1----------------1---4------1111-------------------------1---------------------1---1---------------------------------------------------1--------------------------------------------------------------------1----------1----222222------------------------2-11-------22----------1-------------1--1-11--------------2---------------------2-2-----222--------------------2---------------------------------------------1------1--------------------------1------------------------------11--11111-11------------------------------1-----------------------1-------2-------------------11----------1--------1---------------------------------------2----------------------------------------2--------------1-------2------2-----2344-----2122222222222222-------2--2-------------1----------1----111----------------------------------------------1-----11------------------------------------------------------------------------------------- ----1---11-1-----2----------1-----------------------------------1--------------------------------------1-1---11--------------------------------------------------------3---------1--1----------1---3-1-
 dium subunit                                                                                            *                *   *      ****                         *                     *   *                                                   *                                                                    *          *    ******                        * **       **          *             *  * **              *                     * *     ***                    *                                             *      *                          *                              **  ***** **                              *                       *       *                   **          *        *                                       *                                        *              *       *      *     ****     ****************       *  *             *          *    ***                                              *     **                                                                                          *   ** *     *          *                                   *                                      * *   **                                                        *         *  *          *   * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8114] PF01254            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 TP2:Nuclear transition protei  -------------------------------------------------------------------- ----------1---------------------------1------------------------------------------------------------------------------11---------------------111-------------------------------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------1----------------------------------------------------------------------------------------------------------------------------------11-1--2----------------------1------------------------------1--------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------- --1---1-1---112132--1-1-2-11--121--------1122213--211-321111------------2-11-------------1--3111-----11-------121-2-111--3124215-2-3-124-1-12114--13-----121-----11--12--11-2---1--------11121---212--2
 n 2                                                                                                           *                           *                                                                              **                     ***                                                                   **                                                                                                                                                                  *        *                                                                                                                                  ** *  *                      *                              *                          *                                                                                                                                                                                                               *                                                                                                            *   * *   ******  * * * **  ***        *******  *** ******            * **             *  ****     **       *** * ***  ******* * * *** * *****  **     ***     **  **  ** *   *        *****   ***  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8115] PF04721            162                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        4                          
 DUF750:Domain of unknown func  -------------------------------------------------------------------- ------------------------------------1------------------------------------------------------------------1---------------------------------------------------------------------------------------1----------1---------2-----2---------------------------------------------------------------------1------------------1------------------2------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------1----------------------------------------------------------------------1-------------------------------------------1----------------------------------1--1------------------------------------------------111----------------1-----------------1----------------------------- --------2---------------1--1-------------1---------1-------------------------------------------------1--1-----3121112-11-1-1311215-1-212-1-12-131221111--5-111122311212211-1211---11--------3---1-1----
 tion (DUF750)                                                                                                                           *                                                                  *                                                                                       *          *         *     *                                                                     *                  *                  *                              *                                                                                                                                                                                                        *                                                                                       *                                                                      *                                           *                                  *  *                                                ***                *                 *                                      *               *  *             *         *                                                 *  *     ******* ** * ******* * *** * ** *********  * *************** ****   **        *   * *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8116] PF11072            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2859:Protein of unknown fu  -1------------------------------------------------------------------ -------------1-------1--1------1--------------------111--1----------2---------------------------------------------------------------1------------------------1---------1---------------1-11--------------------------------------------2-------------------------------------------------------------------------------------------1-------------------------------------------1------1-11--------1--1---1-------------------------1-------------------------1--------------11-----------------------------------------5-----------------------1--11--1---32311-----1-2--------------1-2--1-----------------------1-11---------------------------------1-1----------------------------1--1---------12-----1-111---------2----11---------1--1111--------11-1--4---------1--------1-----------1212------------1----11-----------1--111-111---11---1--------------------------1-111------------------------------------------------------------------- -----2-----------1-----------1-------111111----11-2111----1--------1------------------1----1--1---------------2111------------------------------------------1------4-1---21--1---1----2---2-1-11--1--3-
 nction (DUF2859)                *                                                                                *       *  *      *                    ***  *          *                                                               *                        *         *               * **                                            *                                                                                           *                                           *      * **        *  *   *                         *                         *              **                                         *                       *  **  *   *****     * *              * *  *                       * **                                 * *                            *  *         **     * ***         *    **         *  ****        ** *  *         *        *           ****            *    **           *  *** ***   **   *                          * ***                                                                         *           *           *       ******    ** ****    *        *                  *    *  *               ****                                          *      * *   **  *   *    *   * * **  *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8117] PF10997            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2837:Protein of unknown fu  ----1----------------1-----------------------1---------------------- ---1----------1------111--------------1-------1------1--------------------------------------------------1-------------------------1--------1-------------------1--1-----------------------------1111111111111221--21-1111---1---------1------------------------------------1---------------------------------------------------------1-1111111---1-11-------------122114---1--11------------111---2---------1-----------------------11--1------1--------------------------------------------------------------1--1--1113-------1111----1111-11------------------------------------------------1------------1--1---1--1----------1--------------------11-1------------1--2-----1----------------------------------------------------------------------------------------------------------------1---1--------------------------------1---------------------1-----------------------------------------------------1-------------------------------1-- ----5----------1-----1------------------------1-----1-----2-----1-----1-1--11------------------------1---1--121-----------1-----------------------------1-----------1-----2-4------41--11-----31-2-----
 nction (DUF2837)                   *                *                       *                          *          *      ***              *       *      *                                                  *                         *        *                   *  *                             ****************  ** ****   *         *                                    *                                                         * *******   * **             ******   *  **            ***   *         *                       **  *      *                                                              *  *  ****       ****    **** **                                                *            *  *   *  *          *                    ** *            *  *     *                                                                                                                *   *                                *                     *                                                     *                               *       *          *     *                        *     *     *     *     * *  **                        *   *  ***           *                             *           *     * *      **  **     ** *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8118] PF04813            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               1                   
 HNF-1A_C:Hepatocyte nuclear f  -----1-------------------------------------------------------------- --------------1-----------------------------------------------------------------------------------------------------1--1111-------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------1--------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -1---1---1-----2-1--1-1-11-------------------111--11-1--------------1---------------11-2-1-1---7---2--21------1-1131111--132421217-1-4131-21112411511-32111222121-12-----12--1---2-3-----21-----212--1-
 actor 1 (HNF-1), alpha isofor       *                                                                             *                                                                                                     *  ****                                                             *                                                                                                                                                                                    **       *                                                                                            *                                                                                                                                                                                                                *                                        *                                                                                                                                                                                                       *   *   *     * *  * * **                   ***  ** *              *               ** * * *   *   *  **      * *******  ********* * **** *********** *********** **     **  *   * *     **     ***  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8119] PF06115            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF956:Domain of unknown func  -------1-------------------1------1--------------------------------- ------------------------------------------------------------------------------1---------1--1----------2-11----------------------------------------1------------1---------1----1----------------------------------------------11-111111------1---1-11--111---41-1111111211--1113112122311111111111111111111111111111121111111111111-1111111-1--111----1111---1----------------------1------------------------------------------------1----------------------------------------1--------------------------------------------------------------1------------------1--------------------------------1-----------------------------------------------------------------------------------------------------1-1---------1-------------------------------------------------------------------------------1-------1----1-----------------------------------1------------------1-------------------1-------------------------------------------------------- -----------1---------------1------------------------------------------1-1--2-------------------1-----1----1--1-----------------------------------------------1-------1-1--4----------------11--1-------
 tion (DUF956)                         *                   *      *                                                                                                                *         *  *          * **                                        *            *         *    *                                              ** ******      *   * **  ***   ** **********  ******************************************************* ******* *  ***    ****   *                      *                                                *                                        *                                                              *                  *                                *                                                                                                     * *         *                                                                               *       *    *                                   *                  *                   *                                                                    *               *                                          * *  *                   *     *    *  *                                               *       * *  *                **  *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8120] PF06576            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1133:Protein of unknown fu  ---------------1----------------------------------1-------------1--1 ----------------------11---------------2------------------------1-----------------------1----1-----1-1---1-------------------------------------------1----------------1------------------------------------------------------------------------------------------------------------222---------------------------------------------1--1---1--1-------------------------------------1-----------------1---1--------------------------------1-121-------------------------------1------11------------------------------------------------------------1-------------------------------------------------11---1---------1---1-----1---------------------------1----------1-----------11------------------1--34----1---2--1-11--12--------------1-----1-11--11---1-111221------------------------------1------------------------------------------------------------1-1-12--------------------------------------------------------1--------------------- -3--21--11-1-----1----11-----1-------111121---------11--2-----1--12--1---1----------1----1---------1-2------132-------------24---------------------------11----12-1-212----1-3------------112-31--2---1
 nction (DUF1133)                              *                                  *             *  *                       **               *                        *                       *    *     * *   *                                           *                *                                                                                                            ***                                             *  *   *  *                                     *                 *   *                                * ***                               *      **                                                            *                                                 **   *         *   *     *                           *          *           **                  *  **    *   *  * **  **              *     * **  **   * ******                              *                                                            * * **                                                        *                       *  **  ** *     *    **     *       ******         **  *     *  **  *   *          *    *         * *      ***             **                           **    ** * ***    * *            *** **  *   *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8121] PF06088            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 TLP-20:Nucleopolyhedrovirus t  ---------------1---------------------1------------------------------ ------------------------------------------------------------------------------------------------------2------------------------------------------------1------------------1-------1---------------------------------------------------------------------------------1---1--------1---------------------------------------11---111---------------11---1-------------------------------------------------------------------------------------------------------------------------------------------1----11--------------------------------------------------------------------------------------------1---------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2------------------------11-------------------------------------------------- --1-32--11---1--12----11-21--------1--1-1----------1-------112--1--1-------1--1-3111-1------1-121-1--3-1-2-1---1111-1111-1114-13-2-3-211-2-22--1321---222212-11---11-92-1---1------3--1--21-223--1---1-
 elokin-like protein-20 (TLP20                 *                     *                                                                                                                                     *                                                *                  *       *                                                                                 *   *        *                                       **   ***               **   *                                                                                                                                           *    **                                                                                            *                                             *                                                                                                                                                                                                                   *                        **                                                     * **  **   *  **    ** **        *  * *          *       ***  *  *       *  * **** *      * *** *  * * * *   **** **** **** ** * * *** * **  ****   ****** **   ** ** *   *      *  *  ** ***  *   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8122] PF09604            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Potass_KdpF:F subunit of K+-t  -----------------1--------1-----------------------------1----------- -----------------11-1----111-11-1---111---------------1---------2-1-1-----------------------------------------------------------------------------1-1111---1111---11--321-------------1-1--------------------------------------1--------------1-1-----1-------------------------------------------------------------------------------------------------------1------------------------------------11---1-----------------1--1-----1----------1-1--------1--------------------------------------------------------------111-111111111111222111111-------1-1-----------11------------------------------11--------------11----1--1------------------121----------------11---------------------------1---111-1111-21--11--1-----1-1-111----1-------11-----1-1-111111---1----1--11-1----------------11------------------------------111-11-----1--1111----------1-------1-----111111-11---------------------------------------------------------------1 ----------------------------------------------1------------------------------------------------------1--------1-------------1------------------------------------------1-11----------------------------
 ransporting ATPase (Potass_Kd                   *        *                             *                             ** *    *** ** *   ***               *         * * *                                                                             * ****   ****   **  ***             * *                                      *              * *     *                                                                                                       *                                    **   *                 *  *     *          * *        *                                                              *** *********************       * *           **                              **              **    *  *                  ***                **                           *   *** **** **  **  *     * * ***    *       **     * * ******   *    *  ** *                **                              *** **     *  ****          *       *     ****** **                                                               *                                               *                                                      *        *             *                                          * **                            
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8123] PF10962            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2764:Protein of unknown fu  -----------------1-------------------1--------------1--------------- ----------------------------------------------------------------------------------------1111-111--------1----111111111111111------------------------111-----------1---------------------------------------------------------1-----------------------------------------111---------------------11----------------------------------1-----------------------1-----3---------------------------------------------------------------------11--------------------------------------------------------------------------1----------------------------------------------------------------------------1--------------1------------------1-1-----------------------1----------------------------------------------------------------------------------------------------------1--11-11-----------11-------1-------------------------------------------------------------------------------1-------2--1111322322324----------------------------1------------ 12111---1---1-----------------1--2-------------1---11---------1-1---1----1----1--111-2---------1--------11-----1---12121--1-1--116-311111-1-1-------------------2-23-------3--1-----------111-1-1--1---
 nction (DUF2764)                                *                   *              *                                                                                                        **** ***        *    ***************                        ***           *                                                         *                                         ***                     **                                  *                       *     *                                                                     **                                                                          *                                                                            *              *                  * *                       *                                                                                                          *  ** **           **       *                                                                               *       *  *************                            *             *****   *   *                 *  *             *   **         * *   *    *    *  *** *         *        **     *   *****  * *  *** ****** * *                   * **       *  *           *** * *  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8124] PF07168            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       1           
 FAE_3-kCoA_syn1:Fatty acid el  ------------------11-1---1111-1-------------------------------1----- --2----------------------1------------11---------------------------------------------------2-2------1-------2-1----1-------------1---------------1---------------11-----1-----------------------------1------1-------------------111-----111-1121-1111----1--1---------------------------------------------------------------------1------------1--111--1------------1----------------1-------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1---1------------------------------------------------11----1----1----------------11---1---------------1---1----1-------------11---------------------------------------------------------------------------------------------------------1--------2----2------------------------------------------------------------------------------------1------1 ----11--1---121--------111---1--------1-----------------2------------------------11-1----11----1-----1---2--5-------------------------1----2---------1-----1-1--2-1---1----1----1--11---44523-921------
 ongase 3-ketoacyl-CoA synthas                    ** *   **** *                               *        *                      *            **                                                   * *      *       * *    *             *               *               **     *                             *      *                   ***     *** **** ****    *  *                                                                     *            *  ***  *            *                *             *                                                                                                                                                                                     *     *   *                                                **    *    *                **   *               *   *    *             **                                                                                                         *        *    *                                                                                    *      *     **  *   ***        ***   *        *                 *                        ** *    **    *     *   *  *                         *    *         *     * *  * *   *    *    *  **   ***** ***      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8125] PF10378            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 RRM:Putative RRM domain        ------------------------1------------------------------------------- -----1-------------------------1-------------------------------------1--------------------------------------------------------------------------------1---------------------------------1-----1------------------------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111--1----------------------------------2-------------------------------------------------1----1--------------------------------------------------------1113-----------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------- ---------------11221112121111111111111111-11111131111111112322111111-212-2131-11111211-11--31-142---1-------11---21-1--------1-121-1-1131----2--1---1------------1--12211-------2---------22-11----1---
                                                        *                                                 *                         *                                     *                                                                                *                                 *     *                                                                        **                                                                                                                                                                                                                                                                                                     ***  *                                  *                                                 *    *                                                        ****                                                                 *                                                                                                                                                       ************************** ************************** *** **** ******** **  ** ***   *       **   ** *        * *** * ****    *  *   *            *  *****       *         ** **    *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8126] PF10634            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Iron_transport:Fe2+ transport  ------------------------311111-2------------------------------------ ------------------------------------------1----------------------------1---111----1----------1--------1----1------------------------------------------------1-------------------------------------------------------------------11111--------------------------1-------------1------------------------1---------------------------------------------------------------------------11------1-----1--------2--21111111111---------12------------------------------11111111-11--3-1-----------------------------------111111111111111111111111-1121---------------1---11--1--11-----------1-1----------------1----------------1111222221----------1-----------------------1---------1-------1------1-----------1---------------------------11--1--------------------------111111-11111--------------1------11--1------1-------------------------1-1---------------------------------------------------------11--------------------1------------------- -----------------------1-1--------------------------------------------------------------1---------------11--1-2------1--------------------------------1-1---------1-------1-1--1-----------------------
  protein                                               ****** *                                                                               *                            *   ***    *          *        *    *                                                *                                                                   *****                          *             *                        *                                                                           **      *     *        *  ***********         **                              ******** **  * *                                   ************************ ****               *   **  *  **           * *                *                **********          *                       *         *       *      *           *                           **  *                          ****** *****              *      **  *      *                         * *                                                         **                    *                                           * *                                                              *               **  * *      *                                * *         *       * *  *                       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8127] PF07789            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1627:Protein of unknown fu  --------------------------------1----------------------------------- ----1------1--1----------------------------------11------1------------------------------------------------1-------------------------------------------1----------------------------------11-------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------11-------------------------1---1-----------------------------------------------------------------------------1-------1111111--------------1-1----------------------1------------------------------------------1-------------1111-------------------------------------------------------------1-------67-1--11--7-111-3--17-1-----------1-------------1------1----1---1-11--1--12-------------------------------------------2---------------11------------------------------------111---1-------------------------------------------------------1 ------1-21--1--1-----111---11-----1---------11-2--1112-----1-----------1---1-----------------2--1-----------2-1-1---1----2---211-6--11-12--111111-----2--------1----1-----1-1----1----------2-1-1--1--1
 nction (DUF1627)                                               *                                        *      *  *                                  **      *                                                *                                           *                                  **                   *                                                                                                                                                                      *             **                         *   *                                                                             *       *******              * *                      *                                          *             ****                                                             *       ** *  **  * *** *  ** *           *             *      *    *   * **  *  **                                           *               **                                    ***   *                                                       *       * **  *  *     ***   **     *         ** *  ****     *           *   *                 *  *           * * *   *    *   *** *  ** **  ******     *        *    *     * *    *          * * *  *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8128] PF05571            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF766:Protein of unknown fun  ---------------------------------------------------1-------------1-- ----------------------------------------------------------11----------1-----1----1------------------------1----------------1-------------------------11-------------------1----------1---------1-11111---------------------------------1---------------------1----1------11-----------------------------------------------------------------------------1------1---------------------1---------------------------------1-----------1--------------------------------------------------------------------------------------------------------1--1----------------------------------1--------------------------------------------------------------------------------------12--1-------------------------------------------------------------------------------------------------------------------------------------------------1-----1----111---------------------------------------------111---11--------------------------------------1---------1 -31--1-----1--------1111-21------------------------------------------------------------------------------6-1-121111111211112424314-2-22221111122-112-11211-1112--11111-12121112-1--1-----------1--1111-
 ction (DUF766)                                                                    *             *                                                             **          *     *    *                        *                *                         **                   *          *         * *****                                 *                     *    *      **                                                                             *      *                     *                                 *           *                                                                                                        *  *                                  *                                                                                      **  *                                                                                                                                                 *     *    ***                                             ***   **                                      *         *  **  *     *        **** **                                                                              * * ********************* * *********** *** ***** ****  ***** ******** *  *           *  **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8129] PF09246            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 PHAT:PHAT                      ----------------------------------------------------1--------------- -1------------1----------------------------------------------------------------------1---------------------------------------------------------------------------------------1-----------------------------1---1-------------------------------------------------------------------------------------------------------------1--------1----------1-------1---1-------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------1-1------1------------------1---------------------------------------------------------------------------------------------------------------1111-------------------------------------1-----------------------1------------------------------------------------------------------------------------- 11---1--1-11-----3--------------------------------1-------1-------1--------1---------1------------------------216333-312-222331415-21422212251222122--21-621321112-1-2-5221--11-----1----2----1--------
                                                                                    *                 *            *                                                                      *                                                                                       *                             *   *                                                                                                             *        *          *       *   *                                     *                                                                                                                                                                                                     *                                      * *      *                  *                                                                                                               ****                                     *                       *                                                                                      **   *  * **     *                                *       *       *        *         *                        ****** *** ********* *****************  ** ********* * * ****  **     *    *    *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8130] PF10668            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Phage_terminase:Phage termina  -------------------------------------------------------------------- --1------------------------1111-------------------------------1-------------11----------------------1---1-------------------------------------1------------------------11-----------------------1212121---1----1-122-3-1--------3-----------------------1-------------1-------1--1------------------------------------1------1---1-2--11----1-1----32-----1----2------1---11--------1-1----------1-------------------------------2----11-------------------11------------------1--------------------------------1-------1----------1----------------------------1----------1---------------------------------------------------1--111---------1--1-----1--1------1111111111-121--11---------------------------1------1--1111-11--------1-----1------1--1-----------------------------1-------------------------1----------------------------------------------------11-------------------------------------------------------------------------1--- --------1-3------11--------------1-1--------------------------1------------------------1--2-------------2---2----1-----11------------------------------------1-13-111-3-11-1-1--1-----1---11-----1-----
 se small subunit                                                                                      *                        ****                               *             **                      *   *                                     *                        **                       *******   *    * *** * *        *                       *             *       *  *                                    *      *   * *  **    * *    **     *    *      *   **        * *          *                               *    **                   **                  *                                *       *          *                            *          *                                                   *  ***         *  *     *  *      ********** ***  **                           *      *  **** **        *     *      *  *                             *                         *                                                    **                                                                         *            * *      **              * *                          *                        *  *             *   *    *     **                                    * ** *** * ** * *  *     *   **     *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 0002000001200001001230016001234000120000000100000010000000010000000000000120010100000C0101000001001000000000000123450000123020000100000011000100010123400101123456700010000123456789AB1000100001001234012345678900010001020100000012300000123456789ABCD001000000010000001010100000001201210120010123456789A0123456789ABC00101201200000001234567890001001200000000000100000001010000000000101000000001000012340100120001000000100000000010010012000000500001230010123456700100000020000120001000100000001001000000000000000123000123010101234000000100001000000000010000101100010123400001000000000200012200100000001010010000010123400001234562000001000000000000012300001230000000000000001234000000000123456789ABCDEFGHIJKLMNOPQRS0012010000123456789A0123400100120000012345678010000012340123000000120000012300100123450000000234001200123001200123456701011012340000101001230120123000001010100100000000010001001010001200000000100000100000000 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8131] PF03121            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Herpes_UL52:Herpesviridae UL5  -------------------------------------------------------------------- --1-------------------------------------------------------------------------------------------------------------------------1----------------------------------1-------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------1---------------------1----------------------------------------------------------------1----------------------------------------------------------------------------1------------------------------------1----------------------------------------- --11--2-522-11-1------------------11-1-11-----21------------------------------1----------------------1--1--131511211-2121121111324-2-435-12221111212111111312121---111-1--3112-1121311121-121-1112-1---
 2/UL70 DNA primase                                                                                    *                                                                                                                         *                                  *                                                                                                                         *                                                                                                                                                                                                                                                                                                 *                                                                                                    *                     *                                                                *                                                                            *                                    *                                            **  * *** ** *                  ** * **     **                              *                      *  *  ********* ************* * *** ***********************   *** *  **** ********** *** **** *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8132] PF08599            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Nbs1_C:DNA damage repair prot  -------------------------------------------------------------------- -----------------11-1-----111111----------------1----1-1----------1----------------------------------------------------------------------------1------------------------1------------------------------------------------------2---------------------------------------------------------------------------------------------------------------------1-----------1-----1--------------------------------------1-------11----------------------------------1-------------------------------------------------------------------------------------1-1--------------------1------------1-------------------------------------1------1-----------------------------------2----------------------------1-----------------------------------------------1-----------------------------------------1111--------------------------------11-1----------------------------1---------------------------------11--------1----------------------------------1--- ---1-----------11--1--------------111----------2---2-1--1-11-1---------------------1--------12---------1----3-2231121121111-1213-2-3-112111-21111212111212111-113----211--1--12-12-2-1--1412--12-----1-
 ein Nbs1                                                                                                             ** *     ******                *    * *          *                                                                            *                        *                                                      *                                                                                                                     *           *     *                                      *       **                                  *                                                                                     * *                    *            *                                     *      *                                   *                            *                                               *                                         ****                                ** *                            *                                 **        *                                  *       *           **  *              ***          *   * *  * ** *                     *        **         *    * ************* **** * * ****** ***************** ***    ***  *  ** ** * *  ****  **     * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8133] PF03762            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 1      2                          
 VOMI:Vitelline membrane outer  -------------------------------------------------------------------- ------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------1------1--------------------------------1-------------------------------------------1-----------1----------------------------------------------------------------------------------------------------------1--------------------------------------1---------------------1------1----------------------------------------------------------------------------------------------1----------------------1--------------------------------1---------------------------------1------------------------------1--------------------------------------------------------------------------------------------------- --11-1--------1-1----------11--1------------11-----------------------3----------------------1------------1--51-322221112111111-214-1-213-1--121-1-11-121-121283------11---148---541----1--1------1-1---
  layer protein I (VOMI)                                                                                                                 *                                                                                                                                                                                    *                                                                                                              *      *                                *                                           *           *                                                                                                          *                                      *                     *      *                                                                                              *                      *                                *                                 *                              *                                                                                                      ** *        * *          **  *            **                       *                      *            *  ** *************** *** * *** *  *** * ** *** ******      **   ***   ***    *  *      * *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8134] PF10630            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1                                                                              
 DUF2476:Protein of unknown fu  -------------------------------------------------------------------- -------------------------------------------1-1--------1---------------------------------------------------1--------------------------------------------1-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------1--------------------------------------1-------1--1--1-----------------------------------------11---------------------------------------------------------------------------1---------------------1----------1---------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------1----------------------------------------------------------------------------------- -----------------2---------33-111----1222211-11--1---1--11--1-----1----1----1------------3-1--11-11--1------1----11251-13211312316-5-544-12-21211-2241-3------1-----1-2-1-------3------1-112------1--1-
 nction (DUF2476)                                                                                                                               * *        *                                                   *                                            * *                                                                                                                                                                                                              *             *                                      *       *  *  *                                         **                                                                           *                     *          *                     *                                                                                                                                                                                                     *                               *                                                                                                     *         ** ***    ******* **  *   *  **  *     *    *    *            * *  ** **  *      *    ***** *********** * *** ** ***** **** *      *     * * *       *      * ***      *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8135] PF11001            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2841:Protein of unknown fu  -------------------------------------------------------------------- -------------------------------------------------------------------1-----------------------------------1---------------------1------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------1---------------------1------------------------------------------------------------------------------ -1------11------31135533333224122243131112212111112112-11211121-11-111-1111-1111112211--1-1-3---2111-11-11---11---------------------------------1----1-----------1112-1-121-------------51---1----1----
 nction (DUF2841)                                                                                                                                                       *                                   *                     *                  *                                                                                                                                                                                                                                     *                                                                                                                                                                                                                *                 *                                                                                                                                                            *                                                       *                     *                                                                                *      **      ************************************** ******** ** *** **** **********  * * *   **** ** **   **                                 *    *           **** * ***             **   *    *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8136] PF07358            161                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1482:Protein of unknown fu  -------------------------------------------------------------------- --------------------------------------------------------------------1-------------------------------1---1-----------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111--1------------------------1--------------------------------------------------------------------------1---------------------------------------------------1------------------------------------------1------------------------------------------------------------------------------------------------------------1--------------------------------3111-2-2642221241-822222221452322222122111---111111111111111111111111-----------------------------------------------------------------------------------------------2--------------------1--------------------------------------------------------- -----1-----111---1-------------------1111---------------1----------------------------------1---------2-111----1------1----------1----1---------------------1------1--2----1---1----------1-------------
 nction (DUF1482)                                                                                                                                                        *                               *   *                                               *                                                                                                                                                                              ******  *                        *                                                                          *                                                   *                                          *                                                                                                            *                                **** * ********** ************************   ************************                                                                                               *                    *                                                               *     ***   *                   ****               *                                  *         * ***    *      *          *    *                     *      *  *    *   *          *             
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8137] PF07788            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1626:Protein of unknown fu  11--1-22211132534143644------------------------1-----------1----3--- --------------------------------------------------------------------------------------1---------------------------------------1--1-----11-11------11-341--------1--21---------------------------211111-41-111121------111-----------------------------------------------------------------------1-12-2-1-11-----1----------------------------1-1--1---1-----1----------------121-----1--11-------------------------------------------------1--------------------------------------------------------1-----------------------------------------------------------------1----------------------------------------------------1-------------------------------1----------------------------------------------1-------------------------------1-------------------------------------------------------------------1----------------------------------------------------------------------------11111----------------------1---------1----1------------- -----------------------1----------1--1-1111-------1-1-------------------------1---------------1----------1-1---1-----1------1---------------------------------1---1--11-----1----1-----------------1---
 nction (DUF1626)               **  * *****************                        *           *    *                                                                                          *                                       *  *     ** **      ** ***        *  **                           ****** ** ******      ***                                                                       * ** * * **     *                            * *  *   *     *                ***     *  **                                                 *                                                        *                                                                 *                                                    *                               *                                              *                               *                                                                   *                                                                            *****                      *         *    *                                     *          *  * ****       * *                         *               *          * *   *     *      *                                 *   *  **     *    *                 *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8138] PF09249            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 tRNA_NucTransf2:tRNA nucleoti  11111131111111111111111111111111111111111111111211111111111111111111 -------------------------------------1-------------------------------------------------------------------------------------1---------------------1---11----------1-----------------------------------------1---1-------------1-----------------------------------------------------------1--------------------------------------------1----------------------------------------------------------------1-------------------------1---------------------------1---------------------------------------------------------------1----------------------------------------1--------------------------------------------------1---------------------------------------------1---------1------------------------------------------------------------------------------------------------------------1-----1----------------------------------------1---------------------------1----1-------------------------------------------------------------------- -1---2-----1-----------------------------111--1-----------1----------1-----1--1----------1-1--------------1---2-111--1--11-1--1114-1-112----111211-11-1--1-----1--1--112111-----1-----------2-2---1-12-
 dyltransferase, second domain  ********************************************************************                                      *                                                                                     *                     *   **          *                                         *   *             *                                                           *                                            *                                                                *                         *                           *                                                               *                                        *                                                  *                                             *         *                                                                                                            *     *                                        *                           *    *                                                                      *   *     *                             ***  *           *          *     *  *          * *              *   * ***  *  ** *  **** * ***    ****** ** *  *     *  *  ******     *           * *   * ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8139] PF06493            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        3                          
 DUF1096:Protein of unknown fu  -1------------------------------------------------------------------ ---------------11----------1-------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------2----------------1------------------------------------------------------------1------------------------------------------------------------1--------------111--1---332-----------1------------1------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1---------------------------------------------------------------------1---------------------------------------------------------------------------11-------------------------------------------------- ---1-----------111111---1--11----111----------21-----21121----1------------3--------------1-1-----------2---9-3--121--1----11--1-1---1------------1--1---1--1-3-1--2-221---617---7-1-11-13-2-1--1------
 nction (DUF1096)                *                                                                                  **          *       *                                                                                                                                                                                    *                                                                                                                                             *                *                                                            *                                                            *              ***  *   ***           *            *                                                                                                      *                                                                 *                                                                     *                                                                           **                                                      *           ******   *  **    ***          **     *****    *            *              * *           *   * *  ***  *    **  * *   *            *  *   *  * * *  * ***   ***   * * ** ** * *  *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8140] PF07954            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1689:Protein of unknown fu  --1-1-1------------------------------------------------------------- ------1---------------------------------------------------------------------------------1-----------11--1----------------------------------------------------------------------11----------------11111211-112111------111-------122211------------------1-------11-----11--11---------111---------------------------------------------------------------------------1-1-------1-----------------1-----------------------------------------------------------------------------------------11--1--------------------------------------------------------------------------------------------1------------------1-------------------------------1---------1-1-------------------------------------------------1--------------------------2------------------------------------------------------------1---1-1---------------------------------1-----------------------------------------------------------------1--------------3--------------------- 1-1-11--2------2---12------1--1------------111-----1----1--1-1111112122112121111221222---------------11-11----3--1-----------1---1---1-------------------1---1---1----------1------------1--1-1-1--933-
 nction (DUF1689)                 * * *                                                                    *                                                                                 *           **  *                                                                      **                ******** ******      ***       ******                  *       **     **  **         ***                                                                           * *       *                 *                                                                                         **  *                                                                                            *                  *                               *         * *                                                 *                          *                                                            *   * *                                 *                                                                 *              *                      * * **  *      *   **      *  *            ***     *    *  * *************************               ** **    *  *           *   *   *                   *   *   *          *            *  * * *  *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 0002000001200001001230016001234000120000000100000010000000010000000000000120010100000C0101000001001000000000000123450000123020000100000011000100010123400101123456700010000123456789AB1000100001001234012345678900010001020100000012300000123456789ABCD001000000010000001010100000001201210120010123456789A0123456789ABC00101201200000001234567890001001200000000000100000001010000000000101000000001000012340100120001000000100000000010010012000000500001230010123456700100000020000120001000100000001001000000000000000123000123010101234000000100001000000000010000101100010123400001000000000200012200100000001010010000010123400001234562000001000000000000012300001230000000000000001234000000000123456789ABCDEFGHIJKLMNOPQRS0012010000123456789A0123400100120000012345678010000012340123000000120000012300100123450000000234001200123001200123456701011012340000101001230120123000001010100100000000010001001010001200000000100000100000000 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8141] PF08714            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Fae:Formaldehyde-activating e  ---1-------------------1--------111111-----11121122211-------------- --1---------------------------------1---------1-----1-----------1----1-------------1---------------------------------------------------------------------------------1-------------------------------------------------1-----1----------------------------------------------------------------------------------------------------------------1-1-------------------------------------2----------2-----------------------33233333----------------13-------------------------2-------------------------------------------------1------12-1---21-1-1-------22-------2-----434----------------1-----------------------------------------------------------------------------------------------------------------------------------------1-----------------------1----------11111111111-------------2---------------------------------------1------------------------------------------------------11-----------------------------1-------------------- -211------------11------1-----111------------------1------------1-----------1-------1----1--1-1----1---12---1-4-1------------------------------------------1----------26--1-1---13----1-----1----------
 nzyme (Fae)                       *                   *        ******     ***********                 *                                 *         *     *           *    *             *                                                                                 *                                                 *     *                                                                                                                * *                                     *          *                       ********                **                         *                                                 *      ** *   ** * *       **       *     ***                *                                                                                                                                         *                       *          ***********             *                                       *                                                      **                             *                      ***            **      *     ***                  *            *           *       *    *  * *    *   **   * * *                                          *          **  * *   **    *     *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8142] PF09928            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2160:Predicted small integ  ----1---1-----------1----------------------------2------------------ -1----------1--------------------------1---1----------------------------------1----------------------------1------------------1----1-------------------1-------2-------2-------------------------11111--------------------------111111-1--------------------------------------------------------------------------------------------------------1--11--------1-------------1----------------------111---21111----------1---1-----11--211112122211-----1111212111----------------------------------------------------1111-------------11---------1111--111--1111-1121---------------------1--1--11-----2--------1--------------1-------------------------1--1---1----------------------------------------------------------------------------------------------------------------------------------111---------------------------------112-111-111-------------------------1------------------------------------------------------------------------ -----------1------------------------------------------1-----1------------------------------1-1-3---1--------1-1-222------1-1----------1-1----11------1-------1--1--1------2--1-----------1--3--------1-
 ral membrane protein (DUF2160      *   *           *                            *                    *          *                          *   *                                  *                            *                  *    *                   *       *       *                         *****                          ****** *                                                                                                        *  **        *             *                      ***   *****          *   *     **  ************     **********                                                    ****             **         ****  ***  **** ****                     *  *  **     *        *              *                         *  *   *                                                                                                                                  ***                                 *** *** ***                         *                                                                                    *                                          *     *                              * * *   *        * * ***      * *          * *    **      *       *  *  *      *  *           *  *        * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8143] PF07091            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 FmrO:Ribosomal RNA methyltran  -------1111111-----1-------1----------------------------------1--1-- 1-1----------------------1-------------1--2--------------------------------------1------11-------------------------------------1-----1-11112------1--121-------------------------------------11------------------------------------------11111111111111-11-------------------------------------------------------------------------------------------------1----1-------------------1--------------1-2------1-------------11--1------------------------------------------------1--------------11-------------------------12----------------------1---------------------1-------1111------1---------1----------------1-2------------------------------11-------------------11----------------------------------1---1---1-----11----------1---------------------------------------------------1111-----------------11--------11---11-1--------------------------------------------------------------------------------------------------------------- --111-1-1-----12------1----111111--1----1-----21-11132---1--------------1------------------5---------21--1--1111--------2--------1-1-11----1---------------------------------1---------1-------111-----
 sferase (FmrO)                        *******     *       *                                  *  *   * *                      *             *  *                                      *      **                                     *     * *****      *  ***                                     **                                          ************** **                                                                                                 *    *                   *              * *      *             **  *                                                *              **                         **                      *                     *       ****      *         *                * *                              **                   **                                  *   *   *     **          *                                                   ****                 **        **   ** *                                                                                                                  *** * *     **      *    ******  *    *     ** *****   *              *                  *         **  *  ****        *        * * **    *                                 *         *       ***     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8144] PF10798            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 YmgB:Biofilm development prot  -------1-------1----------------------------------1---------------1- -1-------------------------------------------------1-----------------------------------------------1-----------------------1----------------------------1---------1---------------------------------------------1-----------1---------1---------------------1-----------------------------------1111-----1--------------------------------11------1---111--------------------1---------------------------------------------------------1-------1-------------------------------------------------2----111-1------------------------------------------1---1-----1--------------------------------1----------------------------------------------------------------------------1-------------------2---232--2212111--222122222-2223233--2211---11111111111111112-11---1--------------------------1---------1---------------------------------------------------------------------------------11--11-------------------------------------------------- ---------------------1--1--------------------------1---------1--1-----111-1-1121------2----1-----1-----------12-1---2------------2---11----------------------2-1----1--1---1--1------------------------
 ein YmgB/AriR                         *       *                                  *               *   *                                                 *                                               *                       *                            *         *                                             *           *         *                     *                                   ****     *                                **      *   ***                    *                                                         *       *                                                 *    *** *                                          *   *     *                                *                                                                            *                   *   ***  *******  ********* *******  ****   ***************** **   *                          *         *                                                                                 **  **                                                                        *  *                          *         *  *     *** * ****      *    *     *           ** *   *            *   **                      * *    *  *   *  *                        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8145] PF05073            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Baculo_p24:Baculovirus P24 ca  --------1111111------------------1-1--------------1----------------- ----------------------------------------------------------------------------------------------------11-----1---------------1--------------------------------------------15---1-----------------------------------------------------1--11--------------------------------------------------------11111211111------------------------1-------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------1------------------------1---------------------1----------1------------------------------1-------------------------------------------1---1-----1-1--1---1---------------------------------------------------------1-----------------------------------------1---------------------1--11---------------1------------------------------------ -1---1---1-1-----1--1---11--------------------111-2---1-1---------------1-1-11--------12--1-----111-11--7----11--4-11-1-1-112313-6-11-141-1-3--1---2---11--11-----71----1--32----1---1---1--1--4-----1-
 psid protein                           *******                  * *              *                                                                                                                      **     *               *                                            **   *                                                     *  **                                                        ***********                        *       *                                                                                                                                                                       *                                                                                    *                        *                     *          *                              *                                           *   *     * *  *   *                                                         *                                         *                     *  **               *                                      *   *   * *     *  *   **                    *** *   * *               * * **        **  *     *** **  *    **  * ** * * ****** * ** *** * *  *   *   **  **     **    *  **    *   *   *  *  *     * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8146] PF10161            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DDDD:Putative mitochondrial p  --------------1-----------------------------------1--1-------------- ------------------------------------------------------1----------1--1------------1--1---------------------------------1------------------------1----------1-------------------------------------------------------------1--------------------------------------------------11----1-------------------------------------------------11---1-----------------------------------------------11-------------------------------11--1---------1---1------1----1-------------------------------------111---------1----------------------111-----11-1-------------------------------------------------------------------1----------------------------------1------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------111--------------------------------------------------------1------1 1-----1-------1----1------------------1------1-1--1-1----1-111----1--------21--1-------------1----------1--11-23144-11111111111212-1-2312211111121113111-2121121--323-1211-32-1-1----------1---2-----1-
 recursor protein                             *                                   *  *                                                                     *          *  *            *  *                                 *                        *          *                                                             *                                                  **    *                                                 **   *                                               **                               **  *         *   *      *    *                                     ***         *                      ***     ** *                                                                   *                                  *      *                                                                                                                                                                             *                                        ***                                                        *      * *     *       *    *                  *      * *  * *    * ***    *        **  *             *          *  ** ***** ************** * ******************* *******  *** **** ** * *          *   *     * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8147] PF05356            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Phage_Coat_B:Phage Coat prote  ----------------------1-1---------------------1--1------------------ ------1-------1------------------111---------1-----------1---1--1---3-------------------2112---------11-1-----1----1--------1---------------------------------1-------------------------------------------1------------1---------------1-------------------1----------------------------------------------------------------------------------1---------------1-----------------------------------112---2-------------------------1------1--------1----1-----1----------1---1----------------------------------------------1----221-----11---2-1-----1-1----------1-1--1--1--1211111-----------------------------------1----1---1----------------------------1---------------1----1--1--1--------------------------------------------------1--------------------------------------------------------1-------------------------1-111--11------------------------------1---1------------------------------------------------------------------------- ------1--------1121----1-1-----------------1-121-1---21111--------------1------1------1----11--1--------4-----3--1---111----1----2-------1---1------1--11----11--21-1-2-----111-1-1-111-----21--111--1-
 in B                                                 * *                     *  *                         *       *                  ***         *           *   *  *   *                   ****         ** *     *    *        *                                 *                                           *            *               *                   *                                                                                  *               *                                   ***   *                         *      *        *    *     *          *   *                                              *    ***     **   * *     * *          * *  *  *  *******                                   *    *   *                            *               *    *  *  *                                                  *                                                        *                         * ***  **                              *   *                                                                                *        ****    * *                 * *** *   *****              *      *      *    **  *        *     *  *   ***    *    *       *   *      *  **    **  ** * *     *** * * ***     **  ***  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8148] PF07450            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 HycH:Formate hydrogenlyase ma  -----------------------1---1---------------------------------------- -------------------------------------------------------------------------------1----------1--------------1--------------------------------1------------------------1------------------------------------------------------------------------1------------------------1-------------------------------------------------------1---------------1------------2---------1-------1--1-----------------1-------1--1----------------------------------1-------------------------------------------------------------------------------------1----1--------------------------------------------------------------------------------111-----------------1-----11----1------------------------------------111111-2221211122-22222112222122222221111---1111111111111111112221122--1---------------------------------1---------------------7----------------1-------------------------1--------------------------------------------------------------1--------- -1---------1-----1-------1------------------------------1--------------------------1--1-1------1-------------------1----------1-----------1----------------2--------------2-1---------------1----212-5-
 turation protein HycH                                 *   *                                                                                                                        *          *              *                                *                        *                                                                        *                        *                                                       *               *            *         *       *  *                 *       *  *                                  *                                                                                     *    *                                                                                ***                 *     **    *                                    ****** ********** ***********************   *************************  *                                 *                     *                *                         *                                                              *           *         *     *       *                              *                          *  * *      *                   *          *           *                *              * *               *    *** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8149] PF09963            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2197:Uncharacterized prote  ------------------------1----------------------1----1------1-------- --------11------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------112221213112211211-11113112112121111111---111111111111111-111-----------------------------------------------------------------------------------------------------1-11---1--1----------------------------1----111-111111------------------------------------------------------1------------------------------------------------------------------------------------1-----------------------------1---------------1---------1--------------1-1-----------------------------------------------------1------------------------------------------1--------------------------1--------------1------------------------------------------------------1-----------------111-1------------------------------------------------------------------------------- ----1-----------1--------1-------1-2-------211-1-------1----------------1----------------12-111------2--------61--1-----11-1---212-1-11-1--1-------------1---11--1--1-1-----------------------111--1---
 in conserved in bacteria (DUF                          *                      *    *      *                 **                                                                                                                                                            *                        ****************** ********************   *************** ***                                                                                                     * **   *  *                            *    *** ******                                                      *                                                                                    *                             *               *         *              * *                                                     *                                          *                          *              *                                                      *                 *** *                                                                                    *           *        *       * *       *** *       *                *                ** ***      *        **  *     ** *   *** * ** *  *             *   **  *  * *                       ***  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8150] PF11856            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3376:Protein of unknown fu  ---------------------------1---------------------------------------- --1--------------22-2-----11111-----2-11-314-------------1-----12-1------------------------------------------------------------21-----1--------1---1-----------------1-----------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------11--1121-1--------------------2-1-------------1-----1-------------------------------1111-------------1------1-1---1-----------3---1--11-----------------------1--------------------------2---1---------------------------11-----------------------------------------------------1------------------------------1--------------------------------------------------------1---------------------------1-----1---------------------------------------------1-------------------------------------------------------------1-- ---------1------1--------------------111222-1------------1-1-----------------------------1-21-1----1---1----5----1---111--3-11-112-1-211111-1-1-1-1--11--11----------42--1------11-11-2-1---11-2-2-123-
 nction (DUF3376)                                          *                                           *              ** *     *****     * ** ***             *     ** *                                                            **     *        *   *                 *                 *                                                                                                                                                                                               *                                  **  **** *                    * *             *     *                               ****             *      * *   *           *   *  **                       *                          *   *                           **                                                     *                              *                                                        *                           *     *                                             *                                                             *            *      *                    ****** *            * *                             * ** *    *   *    *    *   ***  * ** *** * ****** * * * *  **  **          **  *      ** ** * *   ** * * *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8151] PF10511            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      7                    1                                                       
 Cementoin:Trappin protein tra  ----------------------------1--------------------------------------- ------------------------------------------1-------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------111-----------------------------------1------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------- ------1-1---------------------------------------------------------------------------------1----------------------1-1-222--3----2-2-2-2232211214853--3-242---1--------------------------------1---------
 nsglutaminase binding domain                               *                                                                                  *                                                             *                                                                                                                                                                                                                                                                  *                                                         ***                                   *                                                                                                                        *                                                                                                                                *                                                                                        *                                                                                                                           * *                                                                                 *                      * * ***  *    * * * *************  * ***   *                                *         
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8152] PF08004            160                                                       1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
 DUF1699:Protein of unknown fu  --------------------------------1---------1-1---32990-1111-11--11--- ------------------------------------------------------------------------------------1-21---------------11---------------------------1------------1--1----------------1---------------------1------------------1--1-----------------------------------------1------------------------1-----------------------------------------------1-1-------1---111-----------1----11--1-1-------------------1--1----------------------------------------------------1------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------1--------------------------------1-------------------------------------------------------------1111111111111111------------------------1------1111-----------------------------------------------------------------------------------1-----------------------------------1------1------1------------- --------2-----------11-----1-11-1----1-111211113--------1--------------1---2----1----------2-----------1-2------211--------1---1--------------1-1--------11---1-1-11-114---12---------------------11-11
 nction (DUF1699)                                               *         * *   ***** **** **  **                                                                                        * **               **                           *            *  *                *                     *                  *  *                                         *                        *                                               * *       *   ***           *    **  * *                   *  *                                                    *                                                                              *                                                                                                       *                                *                                                             ****************                        *      ****                                                                                   *                                   *      *      *                      *           **     * ** *    * *********        *              *   *    *          *           * *      ***        *   *              * *        **   * * ** ***   **                     ** **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8153] PF09480            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 PrgH:Type III secretion syste  ---------------------------------1---------------------------------- ------------------------------------------2------------------------------------------1-------------11-------1---------------------------11------------1------------2----------1---------------1------------------1-------------1----------------------------------------------------11------------------------------------------------------------------------------11------------------------------------------------------------------------1------1-------1----------------------------------------------1------1-----22221-122-----2222-2--------------111------------11---1-11------1-1----1-1------------1------------------------------------------------------1-------11---------------------11-111--1-11--1-1---1-1--1-----------1-21111111111111111--111--12-1-------------1--------1---1---------1--------------1----------11-----------------------------1-----11-1-11----------------------------------------------------------------1 -----1--111------2-------------11------------111----------1111----1-------------1----------1------------1-------1-----1-------1--2---1-1--------11--1------------1-21111---1--------1------1--1-2------
 m protein PrgH-EprH (PrgH)                                      *                                                                             *                                          *             **       *                           **            *            *          *               *                  *             *                                                    **                                                                              **                                                                        *      *       *                                              *      *     ***** ***     **** *              ***            **   * **      * *    * *            *                                                      *       **                     ** ***  * **  * *   * *  *           * *****************  ***  ** *             *        *   *         *              *          **                             *     ** * **                                                                *      *  ***      *             **            ***          ****    *             *          *            *       *     *       *  *   * *        **  *            * *****   *        *      *  * *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8154] PF07618            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 DUF1580:Protein of unknown fu  ------------------------------------1------------------------------- ----1----------11-------------------1--1---1---1------------1--11--1-2------------------------2-----------1---------------------------1---------11--1----------------------------1--------------------1---------------------------------------------------------11------------------------------------------------------------------------------------------------------------------1-5------1----------------------------1-----1-1---------------1-----------12-------------1---------------------------------1------------------------2-11------------------1--1----1----1-------------------------12----------------11--------------------------------------------------------------------------1---------------------------------------1-------------------------------------------------------------------------------------1-------1----------------------------1--------1---2-----------------------------------------------------------1--- -----------211---1---------121111----1111--1----11-2-1---------1-------------------------111-3-2---1-2--1---1------111-12-11--2310-2-323122-111111-----1---1---222--------------1--1---1-2-----1-------
 nction (DUF1580)                                                   *                                    *          **                   *  *   *   *            *  **  * *                        *           *                           *         **  *                            *                    *                                                         **                                                                                                                  * *      *                            *     * *               *           **             *                                 *                        * **                  *  *    *    *                         **                **                                                                          *                                       *                                                                                     *       *                            *        *   *                                                           *               ***   *         ******    ****  *    ** * *         *                         *** * *   * *  *   *      *** ** **  **** * ****** ******     *   *   ***              *  *   * *     *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8155] PF03978            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1              
 Borrelia_REV:Borrelia burgdor  --------------------------------------------------1---------------1- ---------------------------------------------------------------------------------------1--------------1-1---1-1----1-------2-----------2------------1111--------------1--2-----------------1-------------------1--------1-------------------------------------------------------------------------1--1---11-------------------------1--------11----------1---------------------1---1--------------------------------------------------------------------------------------------------------1111111111111-11--------------------------------------------------------------------------------1-----------------------------1------------1------------------1--1----------------------1-----------------------------------------------------1--------1---------------------------------11-----------1-----------------------1----------------1------------------------2-----------------------11---232-1---2----------------------------------------- 1--1----3--1--11---------------------111111--------1----------1-1-1-1-----1-----------11-1----1----------31-111-----1--1-1---1-1-3---1------1--1----1------3--11-111-221--21-12----1----3-1-111---21111
 feri REV protein                                                                 *               *                                                                                         *              * *   * *    *       *           *            ****              *  *                 *                   *        *                                                                         *  *   **                         *        **          *                     *   *                                                                                                        ************* **                                                                                *                             *            *                  *  *                      *                                                     *        *                                 **           *                       *                *                        *                       **   *** *   *                                          *  *    *  *  **                     ******        *          * * * *     *           ** *    *          ** ***     *  * *   * * *   *      *  *    *      *  ** *** ***  ** **    *    * * ***   *****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8156] PF12098            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3574:Protein of unknown fu  ---------------------------------------------------1---------------- ----------1------------------------------------1------1-------------------------2-----------------------1-1---111111--------------------11--------21111------------1-1--1----------------------------------------1----------------------------------------------------------------------------------------------------------------1---------------1---------------1--------------------1--1-----1-------11-11------11----11111-----1-------------11-----------1211111111-111---------------------------------------------1111-1111111--1111111----------------------21------------------------------1------1-----------1------------------------------1------11-------1--------------------------1---11------------------------------11111-------------------1---------1-------------------------------1-----------------------------11---1---1--1-----------------------21-1111111------------21---------------1-------------------------------1-- ----1-1-------------11-----------111-----------1---------13--------------------------------1---1------1----11---1--------------------------1-1-------1---------111-1121---1-1-1----1----------1--12--2-
 nction (DUF3574)                                                                  *                           *                                    *      *                         *                       * *   ******                    **        *****            * *  *                                        *                                                                                                                *               *               *                    *  *     *       ** **      **    *****     *             **           ********** ***                                             **** *******  *******                      **                              *      *           *                              *      **       *                          *   **                              *****                   *         *                               *                             **   *   *  *                       ** *******            **               *                               *       * *             **           ***           *         **                                *   *      *    **   *                          * *       *         *** ****   * * *    *          *  **  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8157] PF06899            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 WzyE:WzyE protein              ----------------------------------------------------1---1--1-------- ----------------111-1-----11-1-----------1----------------------------------------------1-----------1---1--------------------------------------------------------1------------1-----------------------------------------1----------------------1-------------1----------------------------------------------------------------------------------------1---------------1------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------111------------------------------1-1111111-----11--------2----------------------------------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--------------1---111---1----1-------------------------1--1----------------------------------------------------------------------------------------------------- -----------1-----1---------1---------111-11-----1----------1------------------2-----------------------1---------1-1---11--1--11--------1-----------------11-------1--11-----1---1---1----1------2----2-
                                                                                    *   *  *                         *** *     ** *           *                                              *           *   *                                                        *            *                                         *                      *             *                                                                                        *               *                                                      *                                                                                                                                                                      ***                              * *******     **        *                                  ***************** **************************************************** ************              *   ***   *    *                         *  *                                                                                                                 *     *         *         *** **     *          *                  *                       *         * *   **  *  **        *                 **       *  **     *   *   *    *      *    * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8158] PF02982            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Scytalone_dh:Scytalone dehydr  -------------------------------------------------------------------- ----1----------2211-13--12111111222211-----1------------------1-1--12-----------1-------------------------1--------------------------------------1----------------------------1-1--1--------------------------1--1--------------------1--------------------------------------1----------1---------------------------------------------------------------------------------------------------------111------1------------------2--1--------1----------11------------------1------------------------------------113---1--1---2-----------------2----1------1-1----1--------11---------------1---------1---------1--------1--------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------11111----------------------------------------------------1--------------------------------------------------------------------- -----------1---2311122112-2111111-1-----------21-112-311213111-----1----1-------------------3-1-1111----------1------1---------------------1---1-----------------1-----------1--1---1--1-2---3-11--1---
 atase                                                                                                   *          **** **  **************     *                  * *  **           *                         *                                      *                            * *  *                          *  *                    *                                      *          *                                                                                                         ***      *                  *  *        *          **                  *                                    ***   *  *   *                 *    *      * *    *        **               *         *         *        *                                                              *                                                                                                                             *****                                                    *                                                                                 *   ********** ******* *           ** *** *********     *    *                   * * ****          *      *                     *   *                 *           *  *   *  * *   * **  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8159] PF10084            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2322:Uncharacterized prote  -------------------------------------------------------------------- ---------------------2--1------1-----1------------------------1---------------------------1--1------1--1-----------------------------------------------------------------------------------------------------------------1-------------------------------------1--1-1----------------------------------------------------------------1---------------------------------------------------2----------------------------------------------------1--------------------------11-----------------------------------11--1-----111111113221111223222111-1----1111-1211-------11111111111111---111------1-----------------1------------1111-1--------------11------------------------1-----------1----------1----------------------------------------1-------------------------------------------------------111111---1-1111-----------------11------------------------------------------------------------------------------------------------------------ -----1--1-2-111--11-----------------------1---1--1-------------1---------1-------11--------1-1--------------1-------1-------------------------1---1111-1-31-1-1---1------1------21-6---------12---1-1-1
 in conserved in bacteria (DUF                                                                                            *  *      *     *                        *                           *  *      *  *                                                                                                                 *                                     *  * *                                                                *                                                   *                                                    *                          **                                   **  *     ************************ *    **** ****       **************   ***      *                 *            **** *              **                        *           *          *                                        *                                                       ******   * ****                 **                                                                                                                  *  * * ***  **                       *   *  *             *         *       **        * *              *       *                         *   **** * ** * *   *      *      ** *         **   * * *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8160] PF06684            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1185:Protein of unknown fu  -------------------------------------------------------------------- -------------------------------------11--------------2-------------21---------------------------------------------------------------------------1---------------------------------------------11--------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------1---------------1-------111--2---2-------------1-11-21-12--42212111122122----1-----2-3-------------2-------------------------------1-----122111111121----113-11--1--35----------11--123-33-----------------1-------------------------------------------------------------------------------1------------------1-----------------------------------------------------------------------------------------------------------1---------------111-1-1---------1-121-212-111--------------------------2----111---------------------------------------------------------------- --------1-1------11-------1--------------12--------------------1-1-----------------------1----1-----------------------------2----------1---------------------1-------11--------13---1-1-----------11---
 nction (DUF1185)                                                                                                                         **              *             **                                                                           *                                             **                          *                                                                                                                                               *               *       ***  *   *             * ** ** **  **************    *     * *             *                               *     ************    *** **  *  **          **  *** **                 *                                                                               *                  *                                                                                                           *               *** * *         * *** *** ***                          *    ***                                                                         * *      **       *              **                    * *                       *    *                             *          *                     *       **        **   * *           **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8161] PF11041            160                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2612:Protein of unknown fu  -------------------------------------------------------------------- -----------------------------------------------------------------------------------------11----------------------------------------------------1------------------1--1--------111----1------------------------------------------2---------------------------2-2-----------------1--------------------------------------------------6--------2---------------2-------------------------------------------------------------------------------------1-------------11111111----2--------------------------------------1---1---1--2----22---------1--1----1--------1---------------------------------------------------------------11111---------------1-----------1-------------1-----------------------1-----------------1-1------------1---3311------1--12-1-1---1111-5-1--------3-2-------------------------11-2---------1------------------------------------------11-------------2212------------------------------------------------------------ ----1---11--------------1-------------------4112------------1--1-----------------------1------11------------115---------------------------1-----1--------------113-1-11---3--------8-----1---1----1--1-
 nction (DUF2612)                                                                                                                                                                             **                                                    *                  *  *        ***    *                                          *                           * *                 *                                                  *        *               *                                                                                     *             ********    *                                      *   *   *  *    **         *  *    *        *                                                               *****               *           *             *                       *                 * *            *   ****      *  ** * *   **** * *        * *                         ** *         *                                          **             ****                                                                 *   **              *                   ****            *  *                       *      **            ***                           *     *              *** * **   *        *     *   *    *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8162] PF01955            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CbiZ:Adenosylcobinamide amido  11----1-11111111-11-11111111211121-111-----1-212-11111111111-111---- ---------------11--------------------------------------1----11--1-1-111-----------------------11-----------------------------1-1-----11-----837------------------------------------------------11-----------11---1---1---1112----------1-------------------------------------------------------------------------------------------------------------------------1---111-------1---------------------2-----------------1-----2--------11--1-------------12122------------------1--------------11-------------------------------------1--------2--------------------------------------------11-----------------1--2-------1----------------------------------------------1---------1---------------------1-------------1--------------------1----------------------------------------------------------------------------------------------1--------------------------------------------------1111--------------------------------1----------------- -1----------11------------------------------------------------------------------------------------------1---1-11---------------1-1---1---------------------1--------1-1---------2--1----------1--------
 hydrolase                      **    * ******** ** ************** ***     * *** *********** ***                    **                                      *    **  * * ***                       **                             * *     **     ***                                                **           **   *   *   ****          *                                                                                                                         *   ***       *                     *                 *     *        **  *             *****                  *              **                                     *        *                                            **                 *  *       *                                              *         *                     *             *                    *                                                                                              *                                                  ****                                *                   *          **                                                                                          *   * **               * *   *                     *        * *         *  *          *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8163] PF11628            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 TCR_zetazeta:T-cell surface g  ----1---1111111-----------------------------------1----------------- -------------1-----------------------1--------------1---------------------------------------------------------------------------1-----------------1------------------1------1--------------------11111--1--1---1-----------------11-------------------------1------------------1-------------------------------------------1--------1--------------------------------------1--------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1------------------------------------------------1---------------1-----1----------------------1-11111-111111--------------------------------------------------------------------------------------11---------------------------------------------------1---------11--------- -1--------1-1---1-----------------------------11-1-1----------1----------------------------11--1-----1-1-2-------33411-1-221521215-3-426-11311123-121-21-212-12----1--5-------1-------------11------21-
 lycoprotein CD3 zeta chain         *   *******                                   *                               *                       *              *                                                                           *                 *                  *      *                    *****  *  *   *                 **                         *                  *                                           *        *                                      *                                *                                                                                                                                                                                                                                                   *      *                                                *               *     *                      * ***** ******                                                                                      **                                                   *         **           *        * *   *                             ** * *          *                            **  *     * * *       ***** * ********* * *** ******** *** ** *** **    *  *       *             **      ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8164] PF06783            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                         1                                           
 UPF0239:Uncharacterised prote  -----1----------------------------11--------------------11---------- ------------------------------------------------------------------------------1----------------------------------------------------------1-----1-1------------------------1--1-----1-------------11---11-------1--------1-------------1---------------------------------------------------------------1-----------------1----------------------------1---1--------------------------------------------------1------------------------1-----------11--------------------------------------------------------1---------------1---------------------------------------------------------1------------1------------1----------------------------------------------------1------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------11----------------------------1--1--------------------1---------------------- --111------------1-----11--------11--------122--1--1-1-------1--------1----------1-------------------1---1-1---222-21212111111-310-3-524-1111122121-11112111111------31112---2--1----------11-1-----1--
 in family (UPF0239)                 *                            **                    **                                                                                         *                                                          *     * *                        *  *     *             **   **       *        *             *                                                               *                 *                            *   *                                                  *                        *           **                                                        *               *                                                         *            *            *                                                    *                                                                                                                  *                                                                              **                            *  *                    *                         ***            *     **        **        ***  *  * *       *        *          *                   *   * *   *** *********** *** * *** ********** ***********      *****   *  *          ** *     *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8165] PF11697            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3293:Protein of unknown fu  ------1------------------------------------------------------------- -1-------------------------------------------1----------------1--1-1-1------------------------------------1-1----------------------1----------------1-----------------11--------------121---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------1-----------------------------------------------------------1---------111---111------1--------1-----------111--1----------------------------11-------------3-1-----1--1--1-11-----1---1111111111111111111-----------------------------------------------------------------------------------------------------------------------------------------1------1-------------1-1-111------11111111--1-------------------------------------------------------------------------1 -----1----1-1---11----11--1------1---1--------11----1----------11----------1----------------1----------1----5-------2-111-112214-4-1-22---1-1112-1111-1-1211--------1------------124111---121----------
 nction (DUF3293)                     *                                                               *                                           *                *  * * *                                    * *                      *                *                 **              ***                                                                                                                                                                                             *                                                                                   *                                                           *         ***   ***      *        *           ***  *                            **             * *     *  *  * **     *   *******************                                                                                                                                         *      *             * * ***      ********  *                                                                         *      *    * *   **    **  *      *   *        **    *          **          *                *          *    *       * *** ****** * * **   * **** **** * ****        *            ******   ***          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8166] PF06588            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Muskelin_N:Muskelin N-terminu  ------1------------------------------------------------------------- ------------------------------------------------------------------------------------------1-------------11--1------------------------------------1---------------------1--------1----1-----------11111----------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1------1---------------------------------------------------------1---------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------ 1-1---------222--1------11------------------------------------1---------------1-------111-21-111----14333111-1211121312111121122-6-1-12122122212111111121112111254-21112112--21------------1---------2-
 s                                    *                                                                                                                                                        *             **  *                                    *                     *        *    *           *****                *     *                                                                                                                                                                                                                                                                                                                                                *              *      *                                                         *                                                                                       *                                                                                                        *                                                                                     * *         ***  *      **                                    *               *       *** ** ***    ******** ******************* * * ***************************** ********  **            *         * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8167] PF11820            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      111 1        
 DUF3339:Protein of unknown fu  -------1-------------------1---------------------------------------- -------------------------------------1-----------------------------------------------------1----------1---------------------------------------------------------------------------------------------------------------------1--------------------------------------------------1------1---------------------1--5656431-1---------------------------------------------1--------------------------------------------------------------------------------1----------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------1-------------------------------------1--1---1---1----1---11-1--11-111------1--1-111111111111111-1--------------------------------------------------------------------------------------------11---------------------------1---------------------------------------------1----------- -----------------1-----1--------------------------1----------------------------------------1--------1---------11-1-1------1------1---1---11---11--2------1--1-1-----------1----1---------3127-3------1-
 nction (DUF3339)                      *                   *                                                                              *                                                     *          *                                                                                                                     *                                                  *      *                     *  ******* *                                             *                                                                                *                                                                                  *                                                                                                                    *                                     *  *   *   *    *   ** *  ** ***      *  * *************** *                                                                                            **                           *                                             *                             *     *                          *                                        *        *         ** * *      *      *   *   **   **  *      *  * *           *    *         **** *      * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8168] PF09400            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2002:Protein of unknown fu  --------1111-1-------------1-----------------------------1---------- ------------------------------------------------------------------1-------------------------------------------------------------1---------------------------------------1--------------------------------------------1----------------------------------11------------------------------------------------------------------------------------------------------1--------1--------------------------1-----------------------------------2-1-1-----11--------------------------------------------------------------------111111---------1111111------------1------------------------------------------------------------------------------------------------------1111-111111-1--111-------------21--1111111111111-1111111111111111111111-----111111111111111111111111--111112111111-----------------------------1---------------------------------------------1------------11111111---------------------------------------------------------------- -1------------11-2---------------------------------------------------1-------------------------------1---------------1-1-----11--1------------------11-----11----1-1-111-----1--------------------1----
 nction (DUF2002)                       **** *             *                             *                                                                             *                                                             *                                       *                                            *                                  **                                                                                                      *        *                          *                                   * * *     **                                                                    ******         *******            *                                                                                                      **** ****** *  ***             **  ************* **********************     ************************  ************                             *                                             *            ********                                                                  *            ** *                                                   *                               *               * *     **  *                  **     **    * * ***     *                    *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8169] PF11339            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3141:Protein of unknown fu  -----------------------1----------------------------------1----1--12 ---------------1-----------------------1------------------------1-1------------------------------------------------------------------------1-------------------------------------------------------------------------------------------1----------------------1------------11------111-----------------------------------1----------------------------------------------1---------1-------------351131------1------------1321231---1-----1-1---1-15---------------------2-------------------------------------------1111-11-1------1111------13-1221--21-1--2111-----------2---------1-32---1------------------------------------------------------11--1-------------------------------1----------------------------------------------------------------------------------------------------1222---1--------------------------3--------------1--------1-------------1----11----------------1------------------------------------------------------- 1-----1---------1--1------1------1--1----------1-------1------1-----------1-----------------1--1-----1--12--2112-1--------1-------------1-1-------------------1--1---1121-1-------------------1---1--1-
 nction (DUF3141)                                      *                                  *    *  **                *                       *                        * *                                                                        *                                                                                           *                      *            **      ***                                   *                                              *         *             ******      *            *******   *     * *   * **                     *                                           **** ** *      ****      ** ****  ** *  ****           *         * **   *                                                      **  *                               *                                                                                                    ****   *                          *              *        *             *    **                *                                                        *     *         *  *      *      *  *          *       *      *           *                 *  *     *  **  **** *        *             * *                   *  *   **** *                   *   *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8170] PF05908            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF867:Protein of unknown fun  ------------------------2-----------1--1-------------------1-------- -----1----1----1111-11--121111111111--11-1-----------1------------1--2------------------------------1--1------------------------------------------1--------------------------1-----1------------3-----------------4434-------1--1-----1-----------------3344------------------------------1-----------------------------------------------1---------------1--11----22---1-------------2-------------------------------------------2--2--------1--------------------------------------------------------------------------------------1----------------1-11-------------1--------------------3---------------1----------2-2---------1--------------------------------------1------------1--------------------------------------------------1--------------------------------------------------------------------------------------------1--------------------11111111--1------------------------11--------------------1--------------------------1-- --23--------11-----------------------111111---1-----1---1---------1--------------------1---1-1---------------------2-----------------------------------1--------1--11-------------1--------12--1--2-21-
 ction (DUF867)                                         *           *  *                   *              *    *    **** **  ************  ** *           *            *  *                              *  *                                          *                          *     *            *                 ****       *  *     *                 ****                              *                                               *               *  **    **   *             *                                           *  *        *                                                                                      *                * **             *                    *               *          * *         *                                      *            *                                                  *                                                                                            *                    ********  *                        **                    *                          *     **        **                       ******   *     *   *         *                    *   * *                     *                                   *        *  **             *        **  *  * ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 0002000001200001001230016001234000120000000100000010000000010000000000000120010100000C0101000001001000000000000123450000123020000100000011000100010123400101123456700010000123456789AB1000100001001234012345678900010001020100000012300000123456789ABCD001000000010000001010100000001201210120010123456789A0123456789ABC00101201200000001234567890001001200000000000100000001010000000000101000000001000012340100120001000000100000000010010012000000500001230010123456700100000020000120001000100000001001000000000000000123000123010101234000000100001000000000010000101100010123400001000000000200012200100000001010010000010123400001234562000001000000000000012300001230000000000000001234000000000123456789ABCDEFGHIJKLMNOPQRS0012010000123456789A0123400100120000012345678010000012340123000000120000012300100123450000000234001200123001200123456701011012340000101001230120123000001010100100000000010001001010001200000000100000100000000 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8171] PF11644            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3256:Protein of unknown fu  -------------------------1------------------------------------------ ----------------------------------------------------------------------------------------11111111--------1----------------------------------------------1---------------------------------------------------------------------------------11111111111111----------------------1--1----------------------------------------------------------11-----------------------------1--------1--1---------------------------------------------------------------------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------------------1-1----------------------------1--------------------1-----------------------------------------------------------------------------------------------------------------------------1---1-1-------------------1----------11-------------------------------------------------------------------------- ------------1--------1--2----------------------2---1-1-----111---1-1----1-----1--------------1-----------------2---112111231221617-2-32512123-2213221-321521322--1---2----1---------------11-11---11---
 nction (DUF3256)                                        *                                                                                                                                   ********        *                                              *                                                                                 **************                      *  *                                                          **                             *        *  *                                                                                                                     **                                                                                                                                  * *                            *                    *                                                                                                                             *   * *                   *          **                                                                                       *        *  *                      *   * *     ***   * *    *     *              *                 *   *************** * ******** ******* *********  *   *    *               ** **   **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8172] PF09348            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1990:Domain of unknown fun  ---------------------------1------------------1--------------------- ----11-11111--21111-11--1-11111111112111-2---11--222-12--11111---22211------------------------------1---1--------------------------------------2----------11---------1---1------------214--------------1-------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------21---------------------------------11-11-1---------------11------------------------------------------------------------------------11-1----------------1----1--------------------1-------------1-1------------------------------42--------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------11-------------------------1------------------------------1-2------------------------------------------------------------------1-- -1--111-----------1------------21----------2--1---------1--------------------------------------------3------4-------1-------1-----------------------------------------11-------1111611-311231-112---1--
 ction (DUF1990)                                           *                  *                          ** *****  ***** **  * ************** *   **  *** **  *****   *****                              *   *                                      *          **         *   *            ***              *       *                                                                                                                                                                      **                                 ** ** *               **                                                                        ** *                *    *                    *             * *                              **                                                  *                                                                                                                                      **                         *                              * *                                                                  *    *  ***           *            **          *  *         *                                            *      *       *       *                                         **       ******* ****** ***   *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8173] PF03608            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 EII-GUT:PTS system enzyme II   --------------------------------1--------1-------------------------- -------------------------------------------------11------------1---1--------------------------------------------------------------------11-----------------------------------1-----1----------------------1---1-21111--1---1----111111-----------------111--1---11---1-12--11-1-----------111-11---------------------------------1-1--11111111111-2-----------1--------------------------------------------------------1----------1------------1------------------------------------------------------------------------1------------------------------------------1------------------1----------------------------1----1-----------------------------12----------------------------------------1------1121111111--1111-1111-1211111-212-----11111111211121111111--11--1--------------------11-1--------1--------111------------------------------------------111111------------------------------------------------------------------------------- ------1---------------------------------------------------------------1--1-1-------------------1---------1----1----22-------11-----------------------------1---------1-----------------1--------------1
 sorbitol-specific factor                                       *        *                                                                            **            *   *                                                                    **                                   *     *                      *   * *****  *   *    ******                 ***  *   **   * **  ** *           *** **                                 * *  *********** *           *                                                        *          *            *                                                                        *                                          *                  *                            *    *                             **                                        *      **********  **** **** ******* ***     ********************  **  *                    ** *        *        ***                                          ******                                                                                      *                                                               *  * *                   *         *    *    **       **                             *         *                 *              *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8174] PF02079            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 TP1:Nuclear transition protei  ----------------------------------1-----------------------------1--- ---------------------------------111---------------------------------------------------------------------------------------------------------------------------------1-----------2-------------------------------------------------------------------------------------11--------------------------------------------------------------------------11----------------1---------------------------------------------------1-----------1----------------------------------1--1----------------------------------------------------121------11----------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1--------------------------------------------------------------1------------------------------------------------------------------------------------ --1---1-2-------11111-----1-------------------1--1--11------1--1------------------------1---1---111---------1------1-1125222532338-2-3252112414221324132-11---1------1122-1---1-1---111--321---1---1---
 n 1                                                              *                             *                                     ***                                                                                                                                 *           *                                                                                     **                                                                          **                *                                                   *           *                                  *  *                                                    ***      **                                                                            *                                                                                                                                                                    *  *                                                              *                                                                                       *   * *       *****     *                   *  *  **      *  *                        *   *   ***         *      * ************* * ******************* **   *      **** *   * *   ***  ***   *   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8175] PF04163            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Tht1:Tht1-like nuclear fusion  -------------------------------------1------------------1----------- ---------------------------------------------------------------------------------------------------11-------1------------------------1-------------2--------------------11------------------------------------------------------1---1----------------------------------1--------1----1-------------------------------------------1---11-----------------------------------1-------------------------------1-------------------------------------------------------------------------1-----------11--------------------------------------------------------------------------1-----------------1-------------------------------------1----------------------1-1---------------------------------------------------------------------------1---------------------------------------------------------------1----------------------------1------------------------------------------------------------------------------1----------------1------------ --1--1----11----11111-----1111112111112122111121112-2-1111113112121113111--11121111111111--11-11---1-1111----2-1-1----------1---13-1---11-1--------------1-11------1411---3-1-3--------------1-3-1-----
  protein                                                            *                  *                                                                                                               **       *                        *             *                    **                                                      *   *                                  *        *    *                                           *   **                                   *                               *                                                                         *           **                                                                          *                 *                                     *                      * *                                                                           *                                                               *                            *                                                                              *                *               *  *    **    *****     ************************* * *******************  **************  ** **   * ****    * * *          *   ** *   ** *              * **      ****   * * *              * * *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8176] PF12471            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 GTP_CH_N:GTP cyclohydrolase N  --------------------------------------------1---------------1------- --------111----------1---1------1111--21--------------------------------------------------------1--------------------------------------------------------1--------------1------------------------------------------------------------------------------------1--------------------------------------------------------------------1---------------------------------------------------------------111--------------------1111111----------------------------------------------------------------------------------------------------------------1111-----1------1-1---------------------1-1-----1--1-------------1----1-----------------------------------------------1---------------------------1----------------------1------------------------------------------------------------------1111--------------------------------------------------1----1-1------------------------1----------------------1----------------------------------------- -11--------111-11211122121211111112111111211--11111121121111111--111-----1------1-----11112111111112111122--1------1--------------------------------------------1---------------------------111-4111111
  terminal                                                                  *               *                ***          *   *      ****  **                                                        *                                                        *              *                                                                                    *                                                                    *                                                               ***                    *******                                                                                                                ****     *      * *                     * *     *  *             *    *                                               *                           *                      *                                                                  ****                                                  *    * *                        *                      *                                           **        *** *****************************  *****************  ***     *      *     ********************  *      *                                            *                           *** *******
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8177] PF11909            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 NdhN:NADH-quinone oxidoreduct  ---------------------------------------------1--1------------------- --------------2----------------------1--1---2----------------------------------------------------------------------------------------------------1111111111122211211111111111211112221----------111111-1----1-------------11----111111---------------------------------------------111-----------------------------------11---111--1-------------------------------------------1----------------1---1---------------------------1--------------1------1--------------------------------------------------------------------------1-------------1---------1---------------1--------------1-1------------1--------------11----1------------------1---------------1----------------------------------------------------------------------------1-----------------------------------------------1111------------------------------------------------------------11-----------------------------------111-1-------1--------------------------1-------1-- -----------1----------------------------------1------1----1------------------------------1-1---------1-----1-2-1-11-------1----213-2-21--1--112-1111-12-----------1--1-----------1-------2112-11---1---
 ase cyanobacterial subunit N                                                *  *                                  *                      *  *   *                                                                                                    *************************************          ****** *    *             **    ******                                             ***                                   **   ***  *                                           *                *   *                           *              *      *                                                                          *             *         *               *              * *            *              **    *                  *               *                                                                            *                                               ****                                                            **                                   *** *       *                          *       *              *                                  *      *    *                              * *         *     * * * **       *    *** * **  *  *** **** **           *  *           *       **** **   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8178] PF02532            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 PsbI:Photosystem II reaction   ---------------------------------------------1----2----------1------ ----1--------------------1-----------------------------1-----------------------------------1---------1------------------------------------1------11111111111111111-1111111111111111111---------------------1----------------1-----------------1-----------------------------------1--------------------------------------11---111----11111--1--1--------------------------------1-------------1---1---1------111--11111--------1--1------------------------------------------------------1--------------------1-----111-------------------------------1-------1---------1-----------------------------------------------------1-------------------------------------------------------------------11------------------------------------11-1-1------1-11-----1----------------1-------------1111--------------------------------------------------------------1--------------------------------1--------------------------------------------1------ -----1--1-1------2--1---------11----------------11--1-11-11231-------------------------1-------1-----1--1---113--1----------1---------1-------11--1-----------1---11-11--111-4-1------1---11--2---1---1
 centre I protein (PSII 4.8 kD                                               *    *          *           *                    *                             *                                   *         *                                    *      ***************** *******************                     *                *                 *                                   *                                      **   ***    *****  *  *                                *             *   *   *      ***  *****        *  *                                                      *                    *     ***                               *       *         *                                                     *                                                                   **                                    ** * *      * **     *                *             ****                                                              *                                *                                            *            *  * *      *  *         **                **  * ** *****                         *       *     *  *   ***  *          *         *       **  *           *   ** **  *** * *      *   **  *   *   *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8179] PF11170            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2957:Protein of unknown fu  ---------------------------------------------------1---------------- --------------------------------------1---------------11--------------1---------------------------------1---------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------1------------------------------------------------1--1-----------------------------11------------------------------------1--------55555532446222-4444455522332--431---------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------1-------------------------------------------1----------1--------------------------------------------------------------- ----1----1-------------1----------1-----111---------1----------------------------------------1-1------1------14------------------1---1--1--1---------1--------1----1----1----------------2-12--------11
 nction (DUF2957)                                                                  *                                                       *               **              *                                 *                                                         *                                                                                                                                                     *                                                              *                                                *  *                             **                                    *        ************** *************  ***                                                                                                                                       *                                                                                                                           *                                           *          *                                                                    *    *             *          *     ***         *                                        * *      *      **                  *   *  *  *         *        *    *    *                * **        **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8180] PF06722            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1205:Protein of unknown fu  -----------------------------------------------------1-------------- ----1----------11-----------------1-2-----23-----12------1--521-4-7--11-------------------------------------------------------------------1----22-111111--11--1---11--11-1------------11-------------------------1---------------------1----------------------------------------------------------------------------------------------------------------------1----------------------------------11---------2-----------------11-----1-----------11---1--------------------------------------------------------1---1--1-------------1-1------------1----------1----1-------------------2-------------11-----------------------------------------------1----------------------------------------------1--121-111---1---------11---------2-----1111111111111111---1--------------------------------1------------------------------1111-------------------------------------------1------------------------------------------------------------------- ------1----1----------1-----------1-----------1----1-1-1-1----------------------------1---21--1-------1-------1-1----------------1-------------------2---------------3--1----2-1--11---11---1-1-221--1-
 nction (DUF1205)                                                                    *                   *          **                 * *     **     **      *  *** * *  **                                                                   *    ** ******  **  *   **  ** *            **                         *                     *                                                                                                                      *                                  **         *                 **     *           **   *                                                        *   *  *             * *            *          *    *                   *             **                                               *                                              *  *** ***   *         **         *     ****************   *                                *                              ****                                           *                                                                          *    *          *           *           *    * * * *                            *   **  *       *       * *                *                   *               *  *    * *  **   **   * * ***  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 0002000001200001001230016001234000120000000100000010000000010000000000000120010100000C0101000001001000000000000123450000123020000100000011000100010123400101123456700010000123456789AB1000100001001234012345678900010001020100000012300000123456789ABCD001000000010000001010100000001201210120010123456789A0123456789ABC00101201200000001234567890001001200000000000100000001010000000000101000000001000012340100120001000000100000000010010012000000500001230010123456700100000020000120001000100000001001000000000000000123000123010101234000000100001000000000010000101100010123400001000000000200012200100000001010010000010123400001234562000001000000000000012300001230000000000000001234000000000123456789ABCDEFGHIJKLMNOPQRS0012010000123456789A0123400100120000012345678010000012340123000000120000012300100123450000000234001200123001200123456701011012340000101001230120123000001010100100000000010001001010001200000000100000100000000 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8181] PF08105            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Antimicrobial10:Metchnikowin   -------------------------------------------------------1------------ ----------1------11-1-111-11-1-1------------21------2-------------------------1---------------------------------------------------------11-------1----------------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------------------11-----------------1------------1------------------------------------------111------11------2--------111----1--------------11-------------------------------1------1----1------1---------1-----------------------1-----------------------------1--1------------------------------------------11--1-----1--1----------------------1----------------------------------------------------------1--1----------------------------------------------------1-----1--------------------------------------------1------------------------------------------------------------------------ --1-1------2-------2------2121---21-111111121211---1---121-121----------1----------------121-2-1---1-22-----4-1-------11-1-11--111-1--1-1----1-1--1-11-----11-1--111-1-1-111-1--21--------21111111-121-
 family                                                                                *                       *      ** * *** ** * *            **      *                         *                                                         **       *                                                                **                                                                                                                                               **                 *            *                                          ***      **      *        ***    *              **                               *      *    *      *         *                       *                             *  *                                          **  *     *  *                      *                                                          *  *                                                    *     *                                            *                                                                           * *      *       *      ****   ** ************   *   *** ***          *                *** * *   * **     * *       ** * **  *** *  * *    * *  * **     ** *  *** * * *** *  **        ******** *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8182] PF10042            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2278:Uncharacterized conse  --------------------------------------------------------1----------- -1----------------------------------------1------------------------1--------------------------------------------------1-----11-111211-1---------------------1---------11------------------------1111111111211111-----11211------------------------------11-----------------------------------1--------------------------1--------------------------1-1---1--------------1----------1--------------------------------------------------------211----------------------------1-------------------------1------------------1111111-111111111111111------1111-------1-1-------------------2--------------------------------1--1-------------------------------------------------------1-----------------------1------------------------------------------------------------------------------------1--------------------------------------------------------------------1--------------------------------------1--------------------------------------- ------------16-1---21111411------1---------1----12-1-211------------1------------1--1------------1-------2---1-1---1-----------115---1111--11-------1---------------1-----9--11------------------1-----
 rved protein (DUF2278)                                                                 *             *                                        *                        *                                                  *     ** ****** *                     *         **                        ****************     *****                              **                                   *                          *                          * *   *              *          *                                                        ***                            *                         *                  ******* ***************      ****       * *                   *                                *  *                                                       *                       *                                                                                    *                                                                    *                                      *                                                    ** *   ********      *         *    ** * ***            *            *  *            *       *   * *   *           ***   ****  **       *               *     *  **                  *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8183] PF03040            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CemA:CemA family               ----------------------------------------------------------2--------- -------------------------------------------------------------------------------------1-------1------112--------------------1---------------------21221121111111111121-1221-1-1--11---1---------1-------------------------------------------------------------------------11-----------1--------------------------------------------11--------------------1-----1---11--1----------1---------------1---------------------------------------------------------------------------------------18--1--------------------------------------------------------------------------------------------------------------------------------11-----------------1-----------------------------------------------------------------------------------------1-------------------------1---------------------------1----------------------------------1-------1----------------------2---------------------1------------------------------------------1------------- 21---2--------------------------------------------11-1------------------1---1121--1--1----------------1-12---1-1-----121----1-1----------------------------1211--132-4---2--1--112-1222135317-1----1---
                                                                                          *                                                                                               *       *      ***                    *                     ******************** **** * *  **   *         *                                                                         **           *                                            **                    *     *   **  *          *               *                                                                                       **  *                                                                                                                                **                 *                                                                                         *                         *                           *                                  *       *                      *                     *                                          *              **   *                                            ** *                  *   ****  *  *                * **   * *     ***    * *                            ****  *** *   *  *  *** ********** *    *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8184] PF07821            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               5       1           
 Alpha-amyl_C2:Alpha-amylase C  -----------------------------------------------------------1-------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------1------------------------------------------------------------------------------------------------1-------------------------------1--------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------1------------------1----------------------------------------1-------------------------------------------------------------------------------------1------------------1-----------------------------------------------------------11-----2------------------------------------------------ ---------------------------------------------------------1---------------1---------------------------------1----------------1-----------------------------------1-------1--111--4255464557936-35-----1-
 -terminal beta-sheet domain                                                               *                                                                                                                                                                                                                                                                               *                                                      *                                                                                                *                               *                                                  *                                                                                                                                        *                  *                                        *                                                                                     *                  *                                                           **     *                                                                                                          *               *                                 *                *                                   *       *  ***  ************* **     * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8185] PF07948            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Nairovirus_M:Nairovirus M pol  -------------------------------------------------------------------- --1-------------------------------------------------------------------------------------------------------------------------------------11-----------11-----11-------------1-----1------------------------------------------1---------------------------------------------------------------------------------------------------------1-------1--------------------------------------------------------------111-111111------------------------------------------------------1------------------------------1------------------------1----------------------------------------------------1-----------------1-------------------------------------------------1---1---------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------1------------------------------------------------1-------------------------------------- --11----2---1----1-1-----1-------1-----------------1-2--1--11-------------11---------3-------1-2--------1-----21--1223422-2-462213-1-12311--41322223-21--221221---213112-11--11----------11----1--2121-
 yprotein-like                                                                                         *                                                                                                                                     **           **     **             *     *                                          *                                                                                                         *       *                                                              *** ******                                                      *                              *                        *                                                    *                 *                                                 *   *                                                                                                                           *                                                            *                                                *                                         **    *   *    * *     *       *                 * *  *  **             **         *       * *        *     **  ******* * ****** * *****  ******** **  ******   ****** **  **          **    *  **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8186] PF12502            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3710:Protein of unknown fu  -------------------------------------------------------------------- ----111111111111111-1111111111111212111113241111111111111111212111211411111111---------------------------------------------------------------------------------------1---1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------2-----------1-----------------------1--1----------------------------------------------------------------------------------1------------1----------1-------------11---------------------------------------1---------1-1------------1------------------------------------------------------------------------------------------------------------111-----------------------------------------------1-1---------1----------------11111-1----1-----------------------------------------1--------------------------------1---------------------------------------- ---------1------------1----111111----------1111---11-1-1---1----------------------------------23---1--------4-----1-------1----------------------------1----------1-321----------------1----1---------1
 nction (DUF3710)                                                                                        *************** **********************************************************                                                                                       *   *                                                                                                                                                                                             *              *           *                       *  *                                                                                  *            *          *             **                                       *         * *            *                                                                                                            ***                                               * *         *                ***** *    *                                         *                                *                                                  *            *    ******          ****   ** * *   *                                  **   *        *     *       *                            *          * ***                *    *         *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8187] PF11446            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2897:Protein of unknown fu  -------------------------------------------------------------------- ------1---------------11-1-----------------------------------------------------------------1-1----------------------------------------------------1---------211------------------------------------------1--------------11-1---------------------------------------------11--------------1---------------------------------------------11111-1------------------1----------------------------1-----------------------------------------------1-----1--------------------------------1-----------------------------------111111111111111111111111-------------------------------------------1------------------------------------------------------------11-11-1-1111111111111121121-----------------1--------------------------------------------------------1------------------------1---------------------------------------1-11111211111111111----------111-11111112111------------------------------------------------------------------------- -1--1---------------------1-------------------------1-----1-----------------------------------1--------1------4-------------11-----------------------------111211--1-3-32-1112------------224----------
 nction (DUF2897)                                                                                          *               ** *                                                                 * *                                                    *         ***                                          *              ** *                                             **              *                                             ***** *                  *                            *                                               *     *                                *                                   ************************                                           *                                                            ** ** * *******************                 *                                                        *                        *                                       * *****************          *** ***********                                                                           *  *                     *                         *     *                                   *        *      *             **                             ******  * * ** ****            ***          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8188] PF09007            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 EBP50_C-term:EBP50, C-termina  -------------------------------------------------------------------- ---------------------------------------1---------11--------------------------------------------------------------------------------------------------1-------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------1------------------------------2------------------------------------------111111---------35112-1----------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------1------------------------------------------------------------------------------ ------1-----1--1--2-----1------1-1-----------------1----1----------------------------------1-------2-1--------136454-23-1232442215-2-223----3-373121--31-8222121111--------------1----------1---------2
 l                                                                                                                                          *         **                                                                                                  *                                           **                                                                                                                                                              *                                                                            *                              *                                          ******         ***** *                *    *                                                                                                                                                                                                                                    *                                                           *                                                                                     *     *  *  *     *      * *                 *    *                                  *       * *        ****** ** ********** * ***    * ******  ** **********              *          *         *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8189] PF10218            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2054:Uncharacterized conse  -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------11------------------------1----------------------------------------------------------------1----------1------------1---------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111-----1------------------------------------------------------------------------- -11-22--1-11-----11------------------------------1----------------------11-----------1---1------1------221-1-23211-3-2112112121111-1-311212411121111--11-4-11211-2124111153-311-1-221111-23-2-31--22211
 rved protein (DUF2054)                                                                                                                                                                                  *                                                                                 *                                                                                                                                                                                               *                                                                                         **                        *                                                                *          *            *                     *                                                                                                                                                                                                                                     *****     *                                                                           ** **  * **     **                              *                      **           *   *      *      *** * ***** * ************* * ***************  ** * ***** ********** *** * ****** ** * **  *****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8190] PF07515            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1528:Protein of unknown fu  -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------1-------------------11-------------------1----------------------------------------1-----------------------------------------1--------------------------------------------111---------------------------------------1--------------21-1----------------------------------11-----------------------------------------------1-----------------------------------------------------------------------------------4---1-------------------1---1--1---123-1-----1-1-------11111--1-3---1-----------------------------------------------------------1-1-------1-----------------------1------1-111----------1--------1--1---------1-11--2111--------11-1--3---------2--------1------111112111---------1-21----1------------2--221-111---1111-1--------------------------1-111---1---1----------------------------------------------------------- -----1--1---------------------1-1--------11--------11-1---------------------11----------1--1-------------1----12323-1--1----11-------1-1------111--1-11-----1----1-1-3----51-1-----------------1-------
 nction (DUF1528)                                                                                                                                                                                              *                   **                   *                                        *                                         *                                            ***                                       *              ** *                                  **                                               *                                                                                   *   *                   *   *  *   *** *     * *       *****  * *   *                                                           * *       *                       *      * ***          *        *  *         * **  ****        ** *  *         *        *      *********         * **    *            *  *** ***   **** *                          * ***   *   *                                                                 *  *                     * *        **        ** *                     **          *  *             *    ***** *  *    **       * *      ***  * **     *    * * *    ** *                 *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8191] PF04856            159                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 Securin:Securin sister-chroma  -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------1------1-------------1---------------------------------------------------------1-------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------- ----------------11-1--1--------------11111----1---1------3-1-----111--121--112212-1---1-2---111--1---1--1--1-1-2111241112221622310-2-32121121-121122211112211-1--1-1-6131-1-111------1----211-11---3---
 tid separation inhibitor                                                                                                                                                                                                                                                                                                                                                                                                                                     *                                                                                                                                                        *      *             *                                                         *                                                                               *                                                                                                                                                                                                                                            *                                     ** *  *              *****    *   *      * *     ***  ***  ****** *   * *   ***  *   *  *  * * ******************* * ******** *************** *  * * **** * ***      *    *** **   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8192] PF07431            158                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1512:Protein of unknown fu  11121-21111111111111111-----------1------------------1----------1-11 --------------1-------------------1-----1-------------1---------------------------1--1------------------1--------------------------------------1----1-------------1------------------------------------------1--1-11----1--------------21---------------------------------------------------------------------------------------------1-------2-1-----------------------------------------------1--------------1-------1----------1--1-------------1--1------1----------------1-----------------------------------------1--1------------------11---------------------------1----------------------------------------1--------1-------1----1-----1-------------------------1--11---------1--------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-------------1----11--------------- 211-1---2111-----------------------------11-------1--1-----1-1----11---------1-----------1---------1-1--------121323----1--1-112-3---3---------1---1----1-------211141121-4-11-1----1-------2-2---1-11-
 nction (DUF1512)               ***** *****************           *                  *          * **               *                   *     *             *                           *  *                  *                                      *    *             *                                          *  * **    *              **                                                                                             *       * *                                               *              *       *          *  *             *  *      *                *                                         *  *                  **                           *                                        *        *       *    *     *                         *  **         *        *                                                                                                                                                                                                           * *             *    **                *** *   ****                             **       *  *     * *    **         *           *         * *        ******    *  * *** *   *         *   *    *       ********* * ** *    *       * *   * ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8193] PF03415            158                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Peptidase_C11:Clostripain fam  --1------------------1-----------------------1-4--1----------------1 -------------------------------1------------------------------1-------------------------3222-1-----1----2----------------------1-------24411---2-1-----------------------------------------1----------------------11------------1---------------1-----------------------------1-----11---------------------111111111111-------------1--1111111-1-----1111121-------------------------------------------------------------------------------------------------------------------------------------1-----1--------------------1-2------------------------------------------------------------6--------1--------2--------1--1-------------------------------------------------1-1--1---------------------------------------------------------1-2-------------------------------------------1-1----------11--------1---------------------1------------------------------------------------------------------------------------------------1-1-21321-1-- ---1-1--211------1------------111-------------11------------------1---11------2-----------------1-------13---11-----------1----2------1--------------------------12--1------1-1-11----1--1--------2----
 ily                              *                  *                       * *  *                *                                *                              *                         **** *     *    *                      *       *****   * *                                         *                      **            *               *                             *     **                     ************             *  ******* *     *******                                                                                                                                     *     *                    * *                                                            *        *        *        *  *                                                 * *  *                                                         * *                                           * *          **        *                     *                                                                                                * * ***** *      * *  ***      *            ***             **                  *   **      *                 *       **   **           *    *      *                          **  *      * * **    *  *        *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8194] PF09969            158                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2203:Uncharacterized conse  ------2121111111-111---------------1------------------------------11 211-------------------------------1--------1----------1---------1----------211-----11111---------------------------------------------------1----12-2-------------------------------------11----1--------------------1--------1-1111131-1-----------------------------------------------------1----------------------------------------1111-1--1---3--1111--1--1--------------------1------------------------------------------1-1----------1-----11-----1---1---------------------------------------------------------------------------------1---------------------1---------------------1-----------------1-----112111----------------1-----1----11----1-------------------------------------------1-------------------------------------------------------------1-----------------------------------------------------1--------------1--------------------------------------------------111111-----------1---------------------111---1---------- -1---------13311---------1----1------------------1---3--1-----1-----1------------------------1-1--------2-----111-11---------1--1-----------1--------1---1--------12----121-1---------1--1--1-1--1--1--
 rved protein (DUF2203)               ********** ***               *                              ** ***                               *        *          *         *          ***     *****                                                   *    ** *                                     **    *                    *        * ******* *                                                     *                                        **** *  *   *  ****  *  *                    *                                          * *          *     **     *   *                                                                                 *                     *                     *                 *     ******                *     *    **    *                                           *                                                             *                                                     *              *                                                  ******           *                     ***   *            *         *****         *    *                  *   *  *     *     *                        * *        *     *** **         *  *           *        *   *        **    *** *         *  *  * *  *  *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8195] PF07914            158                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       43                          
 DUF1679:Protein of unknown fu  -------1----------------------------1-1-----------1----------------- ---------------------------------------------------------------------------------------------------1--------------------------1-----------1----------11-----1--------------------------------------------1-1------11-----------------------------------------1-------------------------------------------------------------------------------------------1------------------1---1---1------------1------------------------------------------------------1--------------------------------------------------------------------------------------------------------1-------1-------------------------------------------------1---------------------------------------------------1-------------------------------------------------------11-1-----------------------1-------------------------1-1---1---------------------------------------------------------------------1-----------------1----11-------------------------------------------------- 1---1-----------------1-------1111------111---21-----1------1-------11-----1--------1-----1---1---------11---2-----3------------1-----1---------1----11--------1-1-1-1-----18-------------1--11---21---
 nction (DUF1679)                      *                            * *           *                                                                                                                     *                          *           *          **     *                                            * *      **                                         *                                                                                           *                  *   *   *            *                                                      *                                                                                                        *       *                                                 *                                                   *                                                       ** *                       *                         * *   *                                                                     *                 *    **                                                   *   *                 *       ****      ***   **     *      *       **     *        *     *   *         **   *     *            *     *         *    **        * * * *     **             *  **   **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8196] PF10711            158                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2513:Hypothetical protein   -------1---1--------------1-12--------1-1--------2----1-1----------- -1--1-----------------------------------------1--------------2-----1-------------1-----------------------1-1-------------------------1-----------11----1----------11-----------------------------11111--1--1----1-11-------1--------------1-1-1---11--------1----1------------1---1-11---------------------------------1--------------1-----------1-------------------------1---------1------------1-2-----------------------1---------------------1-1-----1-11-11111111------1------------------------------------111--1----------221---1----11--2---------1-11--1------------------------1-------------1---------------------------------------------1---1-----1-------1---2----------------------1----------1---1-1--------1--------------------------------------1-1------------------------1------------1-----------1----1-1111-------12-111----------------------------------1-----------------------1------------------------------------1-- ----11--21-------------------------------------11----4--1-----2------------1-----------------------------1------1------11-1-2----3-2-2------------------1------12--------11----------------------------
 (DUF2513)                             *   *              * **        * *        *    * *             *  *                                         *              *     *             *                       * *                         *           **    *          **                             *****  *  *    * **       *              * * *   **        *    *            *   * **                                 *              *           *                         *         *            * *                       *                     * *     * ** ********      *                                    ***  *          ***   *    **  *         * **  *                        *             *                                             *   *     *       *   *                      *          *   * *        *                                      * *                        *            *           *    * ****       ** ***                                  *                       *                                    *       **  **                                     **    *  *     *            *                             *      *      ** * *    * * *                  *      **        **                            
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8197] PF03691            158                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 UPF0167:Uncharacterised prote  --------111111-----------------1-1---------------------------------- -1----------1----11-11----11111------------7-------------1---------1-1---------------------------------------------------------------------------1--------------1----------------------------------------------1----1-------1---------1------------------------------------------------------1--------------------------------------------------1-1------1---------------------1------1-----------1---------1---1--------1----1--------------1----------------------------------------------------------------1----------1--1----------------1--1-------------1-------1---1------------1--1--------1-----------------------1------------------------------1--11---------1--1-1-------------------------1---1---11--111---1-1---111111------------------------------1-----------------------------1------------------------------1111----1----------------------11111---1-11----1---------------------------------------------------------------1--- --111-1---2---1-------1-------1--1------------1------1--------1------1--------1-11-1-----------2-----1------2--2------------1----1-1---1-------1-----1------------12111-2-1--1--------21-2--2112-223--1
 in family (UPF0167)                    ******                 * *                                    *          *    ** **    *****            *             *         * *                                                                           *              *                                              *    *       *         *                                                      *                                                  * *      *                     *      *           *         *   *        *    *              *                                                                *          *  *                *  *             *       *   *            *  *        *                       *                              *  **         *  * *                         *   *   **  ***   * *   ******                              *                             *                              ****    *                      *****   * **    *                                                               *      *** *   *   *       *       *  *            *      *        *      *        * ** *           *     *      *  *            *    * *   *       *     *            ***** * *  *        ** *  **** ***  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8198] PF10078            158                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2316:Uncharacterized prote  --------------1-----------------------------1-------------1--------- 21---------------------------------------1---------------------------------11---------------------------1---------------------1------------------111-11------------1--11-1--------------1-------1------2--1-1----1--------------1111-----111111111111111------1-11-1---11----------211121------------------------------------------1--------------1------1------------------------1---------------1-1--1-1-----------------------------------------------11-------------1-----------------------------------------1----1--------------------------1--------1--1-------------------------------------------------1--------------11111--------------------------1--1----1--------------1--1----------------------------------1----------------------------------------------------------------------------------1-------1-------1-1111-----------1---------------------------1-1---1-1-11------------------------------------------------------1----- -----------------1------1----1----------------11---1-2------11-------------------111------1--1-------1--1----1-1121------1-----2-4-2-1-2-------------------111--11---1-5--111---1----1---1-------------
 in conserved in bacteria (DUF                *                             *             *          **                                       *                                 **                           *                     *                  *** **            *  ** *              *       *      *  * *    *              ****     ***************      * ** *   **          ******                                          *              *      *                        *               * *  * *                                               **             *                                         *    *                          *        *  *                                                 *              *****                          *  *    *              *  *                                  *                                                                                  *       *       * ****           *                           * *   * * **                                                      *                       *      *    *                **   * *      **                   ***      *