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Ranking of HM:PFM:REP : from 8301 to 8400

                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8301] PF09239            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Topo-VIb_trans:Topoisomerase   1111111111111111111111111111111112211111111111111111111111111---1111 --1---------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------1-------11-----1---------1----------------------------------------------------------------------------------------1--------1-------1-1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------1111111------1-----------------------1121----------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------- -----11----------------------------------------1--21-------1-2-1--------1-----------1---1-----1------------131-----1---------------1------------1-----------------2111------12-111-811111211--1111-1112
 VI B subunit, transducer       *************************************************************   ****   *                                                                                                                                 *                                                          *       **     *         *                                                                                        *        *       * *                                                                                                                                                                           *                                                            *******      *                       ****                                              *                                                                                                                                                                                                                                      *                                             **                                        *  **       * * *        *           *   *     *            ***     *               *            *                 ****      ** *** *********  **** ****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8302] PF09740            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2043:Uncharacterized conse  111----------------------------------------------------------------- ---------------------1---------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------1---------------------------------------------------------------------------------------------1111111111111-------------------------------------------11----------------18------------------------------------------------------1-----------------------------------------------------------------------------1----111----111111------------1-------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------1------------------------------------------------------1-------------------------------------111----------------------------------------------- -1--111-----11-----------------1--1---------1-2---2---------------------------------------2------------11--12-21111131111121211113-11215112122-1--21--11-31122111-11111----1113---------12122-11-------
 rved protein (DUF2043)         ***                                                                                       *                                                                                                                           *                                                           *                                                                                             *************                                           **                **                                                      *                                                                             *    ***    ******            *                                                       *                                                                                                                        *                                                         *                                                      *                                     ***                                                 *  ***     **                 *  *         * *   *                                       *            **  ** ******************** *********** *  **  ** ******** *****    ****         ***** **       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8303] PF08489            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1743:Domain of unknown fun  1111111111111111111111112111111122222222222333322222221111111111--11 --------------------------------------------1---------------------1---1------------------------------------1---------------1---1----------------------------------------1---1------------------------------------------------------------------------------------------------------------------------------1111111111111-------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------2----------------------------------------- -1--1-------1-------1--1--------1-1-----------2--------1-----------1----------1------------------------112--------1-------------------------------1------1----------1-1-1---1----1-7--------2----------
 ction (DUF1743)                ****************************************************************  **                                             *                     *   *                                    *               *   *                                        *   *                                                                                                                              *************                         **                                                                                                                                                                                                                                           *                                                           *                                                                                                                                                                            *                                                                 *                                           *  *       *       *  *        * *           *        *           *          *                        ***        *                               *      *          * * *   *    * *        *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8304] PF10923            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2791:Protein of unknown fu  11------1111111-------------------1--------111---------------------- -1-------------------1--------------------1-1-------------------122-112-----------------------------1---2-1---------------------1---1-------11--11-1----12----2--1--11113-----------------------------11-------------------------------1---------------------1-1--1-1-1--------------------------------------------------------------------------1-11----1--1------11-----1-1---3--------------------1---2-11------------1---2----------------------1----1---1------------------------------------------1-------1-1-------------------1------1-1----------1---11------2---1--------------------------------1------1--3-2---1--------1-------------------1----1-------1------------1--------------------------------------------------1------------------------------------------------------------1------------------------------11-11--111111----------------1-----------------------------------------------------------------------1------------ --------------1--1-------------------------1---------11---------------1----------11------------------1--11--111----1--------------------1-------1-----1------------1---1--1-------1----1-3--1--12--4---
 nction (DUF2791)               **      *******                   *        ***                        *                   *                    * *                   *** ***                             *   * *                     *   *       **  ** *    **    *  *  *****                             **                               *                     * *  * * *                                                                          * **    *  *      **     * *   *                    *   * **            *   *                      *    *   *                                          *       * *                   *      * *          *   **      *   *                                *      *  * *   *        *                   *    *       *            *                                                  *                                                            *                              ** **  ******                *                                                                       *                           *  *                         *         **               *          **                  *  **  ***    *                    *       *     *            *   *  *       *    * *  *  **  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8305] PF04895            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF651:Archaeal protein of un  111111222222222222222122111111111111-1111112111111111111111121112-11 ------------1-----------------------------------------------1---1----------------------------1------------------------------11--------------------1-------------------11-------------------1---------------------------------1--------1-----------------------------------------1----------------------------------------------------------------1----------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------1-------1-----------------------------------------------------------------------11--11----1---------------------------------------------------------1----------------------------1-1-1--111------------11-------------------------------------------------- ------------------1-1---------------------------------------11-----------1---------------111------------------------------1-4--2-------1---21----1--------------1----41--1-------1--1-------21----1-1-1
 known function (DUF651)        ************************************ **************************** **             *                                               *   *                            *                              **                    *                   **                   *                                 *        *                                         *                                                                *                                                                            *                                                                                                                                       *                                                                                                                 *       *                                                                       **  **    *                                                         *                            * * *  ***            **                                                                     * *                                       **           *               ***                              * *  *       *   **    *              *    **  *       *  *       **    * * *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8306] PF04473            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF553:Transglutaminase-like   --1--1-----------------2-----------2213222211311-1121--222312------1 -------------------------------------1--------------------------------------------------------1--------------------------------------------------1----11-----------------1-----------------1----------1------11-------------11--------------------------------1------1-------1------------------1-----1----------------1--------------------1--------1------------11111--------11-----1-----------------------------------------1---------------------------------------------------------1-------------------------11----------------1-------1--1---------1--------------1----------1-------1--------------1---------------------------------------1--1-------1-------------------------------------------------------------1-------------------------------------------------------1------1111-------------------------------------------------------------------------------------------------------------------1------------------------------- ----1--11---------------------1--------11-----1-----11---------11----1----------------------------------3----1-------111-111211111-1-111---1--12-111------13-11----4-12---1--3--------------1----1-----
 domain                           *  *                 *           ************* ****  ******      *                                      *                                                        *                                                  *    **                 *                 *          *      **             **                                *      *       *                  *     *                *                    *        *            *****        **     *                                         *                                                         *                         **                *       *  *         *              *          *       *              *                                       *  *       *                                                             *                                                       *      ****                                                                                                                   *                                    *  **                     *        **     *     **         **    *                                  *    *       *** ********* * ***   *  ** ***      ** **    * **   *  *              *    *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8307] PF05830            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 NodZ:Nodulation protein Z (No  --1----------------------------------------------------------------- -----------------------------------------------------------------1---------------------------------11--------------------------------------------------2------------------------------------------------1--------1--1-------------------------------------------------1-1--------------------------------------------------------11--------------3------------------------------------1-----------1-------------------------------2------1-1-1---1----2------------------------------------------------------------------------------211111-1--3---------------------------------------1-------1---------1--1-1-------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------2222--1-1-------------------------------------------------------------------------------------------------------------------------------------------1-- ----11--11---------1--------1---------11---------------21--1------1---1---1---11---------------1-------11-1-1-8-11-1-----1---1-----------------1---1-----2231--3641-8-1-----14611--4-1--21-11-1-21-22-1
 dZ)                              *                                                                                                                                   *                                 **                                                  *                                                *        *  *                                                 * *                                                        **              *                                    *           *                               *      * * *   *    *                                                                              ****** *  *                                       *       *         *  * *       *                                                                                                                                                                     ****  * *                                                                                                                                           *       **  **         *        *         **               **  *      *   *   *   **               *       ** * * * ** *     *   *                 *   *     ****  **** * *     *****  * *  ** ** * ** ** *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8308] PF10189            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2356:Conserved protein (DU  ------1----------1-------------------------------------------------- ------------------------------------------------------------------1------------------------------------------------------------------------------1--------11-----------------------1------------1--------------------1----------------1-------------------------------------------------------------------------------------------1--------------------------------11----------------------------------------------------------------------------------1-----1-----------------------------------1-----1---------------------------------------------1-------------------1------------------1-----------------------------------1----------------------------------------------------------------1-----------------------------------------------------------------------------------1---------------------------------1-------------------------------------1-------1--------------------1-------------------------------------------------------- --1-121-----111-------------------1--------1---1------1------------------1--------1--------1-----------22--1-2211113-1111211211214-3-222-1-121111-111-12132-1-21223-11-21142111----------1443-21--1222-
 F2356)                               *          *                                                                                                                     *                                                                              *        **                       *            *                    *                *                                                                                           *                                **                                                                                  *     *                                   *     *                                             *                   *                  *                                   *                                                                *                                                                                   *                                 *                                     *       *                    *                                                           * ***     ***                   *        *   *      *                  *        *        *           **  * ******* ************* * *** * ****** *** ***** * ***** ** ********          **** **  **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8309] PF11111            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CENP-M:Centromere protein M (  --------1111111-----1-----------------------------------1----------- -------------------------------------1-------------------------------------------------------------1---------------------------------------------4-------1--------------------------------------------1--------------------------------------------------------------------11--------------------------------------------------------------------------------1----------1-------------------------1-----------------------------------------------------------1-----------------------------------------------------------------------1------------------------------------------------1--1---------1---1----------------------------------------------1---------11111---------------------------------------1--1---------------------------------------------------------------------------------1------------------------11------------------------------------------------------------------11-----1-1------------------------------------------ -1--6-1-------1------1-----------------------------1----11-----------------1-------------11---1--------11--1--311111222221223232-8-2-52332212111--11-1121112111121-1--1------1--11----------------2----
 CENP-M)                                *******     *                                   *                                                 *                                                             *                                             *       *                                            *                                                                    **                                                                                *          *                         *                                                           *                                                                       *                                                *  *         *   *                                              *         *****                                       *  *                                                                                 *                        **                                                                  **     * *                                            *  * *       *      *                             *    **                 *             **   *        **  *  ****************** * * ***********  ** ************* *  *      *  **                *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8310] PF08769            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Spo0A_C:Sporulation initiatio  ---------1------------1-----1---1--------------------1-------------- ------------------------------------------------------------1---1------------------1--------------------2-----------------------1-------------------------11-----------------1----------------1111111111111211121111111111111111------211-----------------------------------------------------------------------------------------11111111112121121111211112--2141133121111111111---------------------1--------------------11---------------------------------------------1----------------------------------------1------------------------------------------------------------------------1-------------------------------------------------1-1----------------1121---2111-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------1------------------------1------------------1------------------------------ --------11--------1--------------1------------------------------11--------------1---1---------2------------111---------------------------------------------------------------11----------2-------------
 n factor Spo0A C terminal               *            *     *   *                    *                                                                           *   *                  *                    *                       *                         **                 *                **********************************      ***                                                                                         **************************  *******************                     *                    **                                             *                                        *                                                                        *                                                 * *                ****   **** *                                                                                                                                                                         *                *                        *                  *                                       **        *              *                              **              *   *         *            ***                                                               **          *             
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8311] PF07262            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1436:Protein of unknown fu  --------------1----------------------------------1-----1---1-------- --------------------------------------------------------------------------------------11--1---------1------------------1111-----------------------1--1-----------------1-------------------11---------1------1------------------------------------------2111------------1----------------------------------------------------------1---1111111-11-------------------------------1---------------------------------------------------------------------------------------------------------------1------------1-------------------------1-1-----------------------------------112-1--------------------------------------------1-----------1------1----------------------------------------------------------------------------------------131---1-1---1-1-11---------------1-----11---------11----------1----------2-------------------------------------------------------------------------1122-------1-----1-1----------------------2----------- -----1------11---11-11-------1111----------1-----------11-------1111------111-21211-1---------1----------1-----------11-1--121-1-----1-1------111--11-2--4-421--121---1---1-11-----------2--31--12-----
 nction (DUF1436)                             *                                  *     *   *                                                                                               **  *         *                  ****                       *  *                 *                   **         *      *                                          ****            *                                                          *   ******* **                               *                                                                                                               *            *                         * *                                   *** *                                            *           *      *                                                                                        ***   * *   * * **               *     **         **          *          *                                                                         ****       *     * *                      *                 *      **   ** **       ****          *           **       ****      *** ***** *         *          *           ** *  *** *     * *      ***  ** *  * ***  ***   *   * **           *  **  **     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8312] PF00913            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      5                                                                                                                                                                                            
 Trypan_glycop:Trypanosome var  ------------------1-------------------------------------------1----- --------------------------------------12--------------------1---1------------------------------1------------1---------------1-------1------------3----------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------1---------1-----------------------------------------------------1-----1------1------------------------------------------------------------------------1----2---111--------------------------2----------------------------1-----------------------------------------------------------------------------------------------1------------------------------------------1--------------------------------------------------1-----------------------------------------------------------1------1----------1-----------11--------1----------------1---------------------------- ------1---0----1-1------11-----21-------------2------1--1--2-1-----------1--1-----1---1---------111---1--1-------11-4--21----1---------1-1-1---11--1---------2113----1------1-----2----111-11-2-1-11-1-
 iant surface glycoprotein                        *                                           *                                            **                    *   *                              *            *               *       *            *                                                                            *                                                                                                                                           *         *                                                     *     *      *                                                                        *    *   ***                          *                            *                                                                                               *                                          *                                                  *                                                           *      *          *           **        *                *                                   *   *    * *      **     **             *      *  *  * *           *  *     *   *         ***   *  *       ** *  **    *         * * *   **  *         ****    *      *     *    *** ** * * ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8313] PF00552            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                             1              1                                        
 Integrase:Integrase DNA bindi  -------------------1------------------------------------------------ -----1----1------11-1----111111------1-----1------------------------3-----------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------1-------111--------------------------------11--------------------------------------------------111------------------------------------1----11-12------------------1-----------------------------------------------------------------------1----1------------1-----1--------------1-1----------------------1-11-----------1---------------1------------------------------------------------------------------------------------------------------------------------------------------------11111111111---------------------------------------------------------------------------------------------------------------------------------------------------------------- -2---------1---2-------------1---1--------------11-------5----11----------------1---------2----------2----1-1-11-5--1---111--1-1---1-----1-1---63--1-1---1----11---13--1-----1-11----1--1---2--1---1---
 ng domain                                         *                                                      *    *      ** *    ******      *     *                        *                                                                                                                                   *                                                                     *       ***                                **                                                  ***                                    *    ** **                  *                                                                       *    *            *     *              * *                      * **           *               *                                                                                                                                                ***********                                                                                                                                                                  *         *   *             *   *              **       *    **                *         *          *    * * ** *  *   ***  * *   *     * *   **  * *   *    **   **  *     * **    *  *   *  *   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8314] PF03506            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1                                  
 Flu_C_NS1:Influenza C non-str  ----------------------1--------------------------------------------- -------------------------------------------1--------------------------------------------1-----------------------------------------------------------------------------1-----------------------------------------------1----------------------------------------------------------------------------------------------------------------------1-----------------------------------------------1---------------------------11-11-11--------------1------------------------------------------------------------------------------------------------------------------------------------------1-----------1-----------------1------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------1----------------------111111111--------1----------------------------------------1--------------------------------------- -1---1------112--1-1111111111--11111111211111113111111-11111111-111111-2111121121-1111111------3111-131-11-11----1----------41-------------1-----------1---------1--1-1---122------2-----1-1-11--------
 uctural protein (NS1)                                *                                                                                         *                                            *                                                                             *                                               *                                                                                                                      *                                               *                           ** ** **              *                                                                                                                                          *           *                 *                                                                                    *                                                                                                            *                      *********        *                                        *                                         *   *      ***  * **********  *********************** ******** ****** ********** *******      **** *** ** **    *          **             *           *         *  * *   ***      *     * * **        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8315] PF03893            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        1          
 Lipase3_N:Lipase 3 N-terminal  ------------------------1-----11------------------------------------ --------------1-----------------------------1-------------------------------------1--------1-------------------------------------------------------1---------------------------------------------------------------------------1--------------------------1--------------------------------1-----------------1111---1111------------------------1--------------------1---------------1--11-----------------------------------1-1---------------1-------------1--11111111----------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------- ----3--------2--12221114342--1111-------1------1121213313---1-1---------1--1--1------1------1---1----1---1---13-------------3----1-1----1------------------11---1-----1---1-----1-----1112541373-------
  region                                                *     **                                                   *                             *                                     *        *                                                       *                                                                           *                          *                                *                 ****   ****                        *                    *               *  **                                   * *               *             *  ********                                                                                                                                              *                                                                                                             *                                                                                                    *                                                                                                              *        *  ***********  ****       *      **********   * *         *  *  *      *      *   *    *   *   **             *    * *    *                  **   *     *   *     *     **********       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8316] PF02927            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CelD_N:N-terminal ig-like dom  ---------------------------2---------------------------------------- 232-1---------------------------------------1-----1-1--------1--1---2-1---------------------------------454-2----------------------------------2-1-------------1------1-----------------------1---------------------------------11111--1-111111-1111111------------------------------1-----------------------------------------------1-----------5---------4----1---------------1---1---11-------------------------------1-------------------------2-1----------------------------------------------------------1----1-------------------------1---------------------------1--------------1-----1------------------1--12-----------------------------11-1-31------------11-1----1----------------1------------------------------------1-----------------------------------------------------------2----------------------------3---------------------------11111111111211--11111------------------------------------------------1---------------3-- ----1---------------------------------1----------11------------------------11----222---------1------1--------------1-------------------1----------------------1----1-11-----1-----1--------------1-1---
 ain of cellulase                                          *                                         *** *                                       *     * *        *  *   * *                                 *** *                                  * *             *      *                       *                                 *****  * ****** *******                              *                                               *           *         *    *               *   *   **                               *                         * *                                                          *    *                         *                           *              *     *                  *  **                             ** * **            ** *    *                *                                    *                                                           *                            *                           **************  *****                                                *               *       *                                 *          **                        **    ***         *      *              *                   *                      *    * **     *     *              * *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8317] PF07590            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1556:Protein of unknown fu  --------------------------------1----------------------------------- ---1---------------------1-------------1-------------------------1-1---------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------7-------------1-2---------------------------------1-----1-------------------------------------------------------------------------1---------------122-----------------------1---1-------------1-------------------------------1-1-------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------1---------------------------------------------1--2-----1-----------------------------------------------------11-- ----------1-1-13-3----------------2--2-2342-1-1----1-2-11-111--------11-1------------------1-2-2-1---4-1---1--21-11211--1---222--2-1---4-1----1--11------1--1-1--21113-31---11--5214------23221---1----
 nction (DUF1556)                                               *                                       *                     *             *                         * *                                       *                                                                                                                                                                                                                                                                          *             * *                                 *     *                                                                         *               ***                       *   *             *                               * *                                                                                                                               *                                                                           *                                             *  *     *                                                     **             * * ** *                *  * **** * *    * * ** ***        ** *                  * * * *   * *   *  ** *****  *   ***  * *   * *    *  **      *  * *  ***** **   **  ****      *****   *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8318] PF10539            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      111          
 Dev_Cell_Death:Development an  ---------------------------------1---------------------------------- ---------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------1----------1--------------------1------------------------11---------------11------------------------------------------------------------------------1--------------------------------------------------1------------1--------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------1--1--------------1-111----------------------------------------------1-------------------------1-----1------------------------ ---111-----1--1-----------------1--1----------1-11-------------------------1-----111-----------------1------4-1222111--1----------------------121-----1--21-----------1----------235---256155-861-23123
 d cell death domain                                             *                                                                                                                          **                                                                                     *          *                    *                        **               **                                                                        *                                                  *            *                                            *                                                                                                                                                 *                                                                                                                                                                        *                                          *  *              * ***                                              *                         *     *                            ***     *  *                 *  *          * **                         *     ***                 *      * *******  *                      ***     *  **           *          ***   ****** *** *****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8319] PF06932            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1283:Protein of unknown fu  -------------------------------------11----------------------------- --------11------------------------------------------------------------------------------11-----------------------------------------------------------------------------1---------------1-------------------------------------------------111-1-11111111----------------------------------------------------------------------------------------------1----------------1-------------------------------------1----------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11121111111111111-11111111111111111111111111111121111112111221--1111-1-1---1----121---------------1------------------------------------------------------------------------------------------------------------------------------------------------ --1---------33-121-11-----------------111---------2-------1-----------------------1---------2--1-----1-11-------1--1----------1------------------------1---11-1--112-11-1-1-41-----3-----1-1--------1--
 nction (DUF1283)                                                    **                                      **                                                                              **                                                                             *               *                                                 *** * ********                                                                                              *                *                                     *                *                                                                                                                                                                                                                                                                  ***************** ********************************************  **** * *   *    ***               *                                                                                                                                                   *         ** *** **                 ***         *       *                       *         *  *     * **       *  *          *                        *   ** *  *** ** * * **     *     * *        *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8320] PF10625            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 UspB:Universal stress protein  -------------------------------------1----------1------------------- ---------------------------------------------------------------------------------------------------------1-----------------------------------------1-----------------------1-------------------------------------1-------1----------------------------------------------------------------------------------------------1-----------1----------------------1----------------------1--------------------------------------11-11-1-----------------------------------------------------------------------------1----------------------1-1------------------------------------------------------------------------1--------------------------------------------------------------1---1-------------11111111111111121-111111111111111111111111111211122122211111111111111--1111111-1111----------1---------------------------------2---------------------------11211111121111-----------------1-------------------------------------------------------- -----1--------------------1----------------------1---------1---1----------------1--------------------1---1----2-------------------------1--------------------1----11-1----4-----1--------1---1--1-111--
  B (UspB)                                                           *          *                                                                                                                             *                                         *                       *                                     *       *                                                                                              *           *                      *                      *                                      ** ** *                                                                             *                      * *                                                                        *                                                              *   *             ***************** ***************************************************  ******* ****          *                                 *                           **************                 *                                                              *                    *                      *         *   *                *                    *   *    *                         *                    *    ** *    *     *        *   *  * ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8321] PF08829            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 AlphaC_N:Alpha C protein N te  ----------------------------------------1--------------------------- ------------1-11111-11111111111111111-11-111-------------------------------------------------------------1--1--------------------------------------11------------------------1-----------------2------------------11--1---------------1-----------------------------------------------111----1-------------------11--------1--------------------------------------------------------------------------------1--------------1--1------11------------1---------1-----------------------------------1-----------1-----------------------1-------------------------1-----------------------------------------------1----------------------------------1--------11----2122--1111--11-----------------1------112-11-----411-1111--31----------------1-------------------------------1-------------------1-------------------1---------------------------11-1--11-------------------------------------------1-----1--------------------------------------- 1----1------11-------1---------111----------1--1-----------111-1-1----12-----1--1--1-----1---1-----1-11------1------1-------------------------1-1----------1-----1131-1-12------1----1---1--1------1---
 rminal                                                                 *                                        * ***** ***************** ** ***                                                             *  *                                      **                        *                 *                  **  *               *                                               ***    *                   **        *                                                                                *              *  *      **            *         *                                   *           *                       *                         *                                               *                                  *        **    ****  ****  **                 *      *** **     *** ****  **                *                               *                   *                   *                           ** *  **                                           *     *                                        *    *      **       *         ***          *  *           *** * *    **     *  *  *     *   *     * **      *      *                         * *          *     **** * **      *    *   *  *      *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8322] PF11811            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3331:Domain of unknown fun  ------------------------------------------1------------------------- -1----1-------1-----------------------1---1---------------11-------------------------------------------------------------------------------------111----1---------2--11111--------------1-----------------------------------1------------------------------------------------------------------------------------------------------------------------------------1--------------------1-----------1------1-1----------------------------------------1---1---------------------------------------------------------------7443461----88661111-1776--1------------11------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1----------------------------------------------------------------------------------------------------1-----------------------------------1----------1------------------------------------------------------- -----------------1------1------11----------1---111-1--11-------------------1-------------------1-----3--------2---------------1--2-1----------1---------------------11---1--12--------13-1-1----1------
 ction (DUF3331)                                                          *                           *    *       *                       *   *               **                                                                                     ***    *         *  *****              *                                   *                                                                                                                                    *                    *           *      * *                                        *   *                                                               *******    ******** ****  *            **                                                                                                                                                      *               *                                                                                                    *                                   *          *                                                                         *      *      **          *   *** *  **                   *                   *     *        *               *  * *          *                     **   *  **        ** * *    *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8323] PF07429            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Fuc4NAc_transf:4-alpha-L-fuco  -------------------------------------------1------------------------ ------1-----------------------------------------------------------------------------------1--1-----------------------------------------1--------------------------1-------------------------------------------------------------1--1-1---------------------------------------------11-------------------------------------1----------------1-----------------------11----------------------------------------1111111-11--------------------------1----------------------------1--------------------------------------------1-----------------------------1----------------------------------------------------1-------------1---------------------1-------1--------------21---------------------11111111111111111-1111111111111111111111111112112121111121221111111111-111111111111-----------------1111---1----1-------------------------------------------------------1----------1---------------------------------------------------11---------- -----1------1-----------------------------------------11---1-1----------------------------------------1-----11--------------22----------------------------------1---11-------1---------11-1--1---------
 syltransferase (Fuc4NAc trans                                             *                               *                                                                                   *  *                                         *                          *                                                             *  * *                                             **                                     *                *                       **                                        ******* **                          *                            *                                            *                             *                                                    *             *                     *       *              **                     ***************** **************************************************** ************                 ****   *    *                                                       *          *                                                   **                *      *                                         **   * *                                        *     **              **                                  *   **       *         ** *  *         
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8324] PF09707            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Cas_Cas2CT1978:CRISPR-associa  --------------------------------------------1--1-1------------------ ---11111-----1-------1---------------1---11-----------------2--1-2-1-1-------------------------------------------------------1---1----2-11---1-----11---1------------------------1-----1--1--------------------------------------11-1--------------------------11-1----------------1-----------1------------------------------------------------------------------------------------------------------------------------------1-----------------------1---1-----11111111-11-2-12--------------------------------------------------------------------------------------1--------------1-----1-1---11---------1-11111--1---1------------------------------1-2----1------------------1----1---------111---111-1------11111--1-11-1--1--1--11------11111111111111-111---1---------------------------1--11-------------------------1------1-11---------------------1-1--1------------111----------11---------------------------------------------------- --------1-----1--1----------------------1-----------1--------------------------------------1---1-1---1-------------1--1--1------12-1-1--------------1---------1----1--------------------11-------------
 ted protein (Cas_Cas2CT1978)                                               *  * *                      *****     *       *               *   **                 *  * * * *                                                       *   *    * **   *     **   *                        *     *  *                                      ** *                          ** *                *           *                                                                                                                              *                       *   *     ******** ** * **                                                                                      *              *     * *   **         * *****  *   *                              * *    *                  *    *         ***   *** *      *****  * ** *  *  *  **      ************** ***   *                           *  **                         *      * **                     * *  *            ***          **                                                             *     *  *                      *           *                                      *   * *   *             *  *  *      ** * *              *         *    *                    **             
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8325] PF12413            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DLL_N:Homeobox protein distal  --------------------------------------------------1----------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------1------------------------------------1-1-----------1---1--------------------------13----114554623222233332334-3-445-23232243-312-32333123323---1------11-----------------1-11---2-
 -less-like N terminal                                                            *                                                                                                                                                                                                                                    **                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     *                                    * *           *   *                          **    ********************* * *** ******** *** ***********   *      **                 * **   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8326] PF06400            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Alpha-2-MRAP_N:Alpha-2-macrog  --------------------------------------------------1----------------- ------------------------------------------------------------------------------------------------------1-----------------------------------------------11-----------------------------------------11--1---1----------------11----1-----1---------------------------------1------1--------------------------------------------------------------1--1----------------------------------1----------------------------------------------1---------1---------------------------11----------------2-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11111----------------------------------------------------------------------------------------------------1-------------------- -1----1----1-----------------2111-------------1------------1---------------2-11----1-----------1---------1----1121114-211122431323-2-224-12122233122--2132262123111-1111221111----------------------1--
 lobulin RAP, N-terminal domai                                                    *                                                                                                                        *                                               **                                         **  *   *                **    *     *                                 *      *                                                              *  *                                  *                                              *         *                           **                *                                                                                                                                                                                                                                                                                                                       * *****                                                                                                    *                      *    *    *                 ****             *            *               * **    *           *         *    ******* ************ * *** ***********  ************* **********                      *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8327] PF08778            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 HIF-1a_CTAD:HIF-1 alpha C ter  ---------------------------------------------------1---------------- 1------1-------------------------------------------------------------1------------------------------1----------------------------------------------------------1--------1--1--------------------------11---1-11---------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------11-----------1--------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1-1---------------------------------------------------------------- ----------------------------------1-----1-------------------1--------------1-------1----12-----------1--------121245422--222451211-2-442221221234111214-26-4223-11----1---------1--------111--1---1-1--
 minal transactivation domain                                                      *                 *      *                                                             *                              *                                                          *        *  *                          **   * **         *                                                                                                                                                                              *                                                                                                                                 **           *                                                        *                                                                                                                                                                                                                       *                                        * *                                                                                                   *     *                   *              *       *    **           *        *********  ********* * ****************** ** **** **    *         *        ***  *   * *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8328] PF12360            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Pax7:Paired box protein 7      --------------------------------------------------------1----------- ---------------------------------------------------------------------------1------------------------1-----1--------------------------------------1--------------------------------------------------------------1-----------1-----------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------1---------------------------1------------------1--------------------------------------------------------------------------------------------------------------------1-------------1---11-----------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------112-1------------------------------------------------------------------------------- ----1---1-1----------------------------------------------1----------------1------------1-----1--11-------------343354221223232-519-7-63412232122-12213222314112------2------1-----------1---1----------
                                                                                        *                                                                                       *                        *     *                                      *                                                              *           *                                                                                                                                                           **                                                                                             *                           *                  *                                                                                                                    *             *   **                                                                                                                       *                                                        *** *                                                                                    *   * *                                              *                *            *     *  **             *************** *** * *********** **************      *      *           *   *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8329] PF09301            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1970:Domain of unknown fun  --------------------------------------------------------1----------- --------------1------1---1-1--1-1222-------------------------------1--------------1--------------------1-----------------------------------1-----------------111-------1--------------11------------------------1--------1---------------11-1-1-1111111--------------------11--------2--------11------------------------1--------------------------------------------1-------------------1--------------------------------1---1-----------1----1----------3---------------------------------------------------------------------111-----1111------------------11----------1------------111------------1-------1------------------------------------------------------------1----1------1-----------------------------------------------111---------------------------------------------------------------------------------------1------------------------------------------1-----1---------------------------------------------------------------- -1----1-31-1--1--------1-2----------11111111---11-------1--111-1--------------1----------122----------------1-1--2--1-1-----2-----------2----------1----------1--------4-1--1-2-33-----2--342-12112---1
 ction (DUF1970)                                                                        *                          *      *   * *  * ****                               *              *                    *                                   *                 ***       *              **                        *        *               ** * * *******                    **        *        **                        *                                            *                   *                                *   *           *    *          *                                                                     ***     ****                  **          *            ***            *       *                                                            *    *      *                                               ***                                                                                       *                                          *     *                                                                  *    * ** *  *        * *          ********   **       *  *** *              *          ***                * *  *  * *     *           *          *          *        * *  * * **     *  *** *****   *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8330] PF08481            154                                                                                                                                                                                                                                                                                                                                                                      11                        1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
 GBS_Bsp-like:GBS Bsp-like rep  ------------------------------------------------------------1------- -------------------------------------------------1------------------------------5----------------------------------------------------------------------------------------------------------------111111111121111------111----------------------------1--------------------------------222----922----------------1---1---9661145664-----------------1----------------------------------1---------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------1-----------------------------------------------------------1----------------------------------------------------------------------------- ------1----------1----1----------1------------1----1-1---1--1---------------------------------2-111------------1----1----------------------1--1------------------1--------------------------------1----
 eat                                                                                        *                                                         *                              *                                                                                                                ***************      ***                            *                                ***    ***                *   *   **********                 *                                  *                                                                                                                           *                                                         *                                                                                                                                                                                                                   *        *                                                           *                                                                                    *          *    *          *            *    * *   *  *                                 * ***            *    *                      *  *                  *                                *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8331] PF03089            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 RAG2:Recombination activating  -------------------------------------------------------------------- -1---------------------------------------------1------------------------------------------1----------------------------1-11--------------------------------------------1----------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------1------------1----------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------- ------1-21122----1------------111---1---------23-----------------131-------11---1----1-1-1-----------1-12--111212143112-11226211-3-2-336-3112122214-11311213131----11-1-----11-111------------3---12112
  protein 2                                                                                           *                                             *                                          *                            * **                                            *                                                                                  *                                                                                                               *            *          *                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    *                                                  * *****    *            ***   *         **                 ***       **   *    * * *           * **  ************ ******** * * *** ********** ***********    ** *     ** ***            *   *****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8332] PF01110            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CNTF:Ciliary neurotrophic fac  -------------------------------------------------------------------- --1-------------------11---------1-11-------------------1--------1----------------------1------1------1-2-----------------------1--------------------------------------------------1--------------------------------------------------------------------11--------------------------1------82---11111111111----------------------------------------------------------1-----1----------1----1111---1-------------------------------1--------1--------1-------------------------------------------------------------------1--11-1----------1------------------11---------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------1-------1-----------1-------------------------1--------------------1-----------11-------------------1--------------111---------------------------------1------------- -----------1-----1--------1-2--------1-1-11------1-1--------1--------------------------------1---1------------11121412-11-21322-12-2-1-2-21221-33-12-13--1-3211-1----1-------------------------1----3-1
 tor                                                                                                   *                   **         * **                   *        *                      *      *      * *                       *                                                  *                                                                    **                          *      **   ***********                                                          *     *          *    ****   *                               *        *        *                                                                   *  ** *          *                  **                                                                                 *                                                                                                                              *       *           *                         *                    *           **                   *              ***                                 *                         *     *        * *        * * **      * *        *                                *   *            ******** ** ***** ** * * * ***** ** ** **  * **** *    *                         *    * *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8333] PF07084            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Spot_14:Thyroid hormone-induc  -------------------------------------------------------------------- ---------------------1---------1-----------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------1----------1--------------------------------------------------------------------------------------------------------------------1-----------------1----------------------------------------------------------------------1------------------------------------1--1-------------1---------------------------------------------------------------------------1----------------------------------------------------------------------------------1-----------------1------------------------------------------------------------1------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1-------------1-------1-------------------1-1---------1-------------------------1-------------1---1-1----254424121-222143-324-4-323-21-221231211-21-323213--1111246221--22--1------12--2--1--1----
 ible hepatic protein Spot 14                                                                                             *         *                                                                                                                                         *                                       *          *                                                                                                                    *                 *                                                                      *                                    *  *             *                                                                           *                                                                                  *                 *                                                            *      *                                                                                                                                                                                                   *             *       *                   * *         *                         *             *   * *    ********* ****** *** * *** ** ********* ** ******  **********  **  *      **  *  *  *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8334] PF07326            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1466:Protein of unknown fu  -------------------------------------------------------------------- ------------------------------------------21----------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------11---111---------------------------------------------------1-1-------------------------------------------1------1--2--------------------------------------------------------------------------------------11----13-------1---11-------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1--1-2----1-----11---1-------------22---11--1111-----212-------------11-11----1-------1--1-----2--1-----3----2322-1131431312-1-324112111121-11111213113-1---13-21511--11--11-----1-1--1----2-1-1-
 nction (DUF1466)                                                                                                                              **                                              *                                                                                                                                                                                *                                             **   ***                                                   * *                                           *      *  *                                                                                      **    **       *   **                                                                                                                               *                                                                                                                                                                                                                                                                  *  * *    *     **   *             **   **  ****     ***             ** **    *       *  *     *  *     *    **** ********** * ************ *********** *   ** *****  **  **     * *  *    * * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8335] PF08167            154                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 NUC201:NUC201 domain           -------------------------------------------------------------------- ---------------------------------------------------------1--------------------------------------1-----1-----------------------------1------------1----1---------------11---------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------1-1------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------1---------------------11--11--1-------1-----------1-------1----------------------1------------------------1111--------------------1-1------------------------1-----------1---------------1--------------------------------------------------------------------1-- ------1-1--12----2----1------111112--111111-111--1----111----1-------------1---1-----------1---1-------12-----2-311111111111221313-1-2-411-121111-1--12--3112311--1-11--13---1-----------4331-13----2--
                                                                                                                                                              *                                      *     *                             *            *    *               **                                                               *                                                                                                                                              * *                                                                                                                                                                        *                                                                                                                *                     **  **  *       *           *       *                      *                        ****                    * *                        *           *               *                                                                    *         * *  **    *    *      ******  ****** ***  *    ***    *             *   *           *   *       **     * ****************** * * *** ****** *  **  *******  * **  **   *           **** **    *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8336] PF11452            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3000:Protein of unknown fu  11----------------------------------------------------------------11 ----221111111112111-1111111111111222121112131111111111211111111111112111---111-------------------------------------------------------------------------1-------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------1-------------------------------------------------------1---------------------------------------------------------------------------------1-------111-11---------------2-------------------1------------------------------------------------11-11-----------------------------------1---------------------------------------11-----1--1---------------1---------------------------------------------------------------------------------------------111------------------1--------------------------------------------------------------------------------------------------- ----------1---1-11-111--1---------1-----1--1-------1-111------------------1-----------------1-----1------1--2--------------------1-1-121----------------1--11-1---11-------------3--1--------1-------1-
 nction (DUF3000)               **                                                                **     *************** ****************************************************   ***                                                                         *             *                                                                                                                                                                                        *       *                                                       *                                                                                 *       *** **               *                   *                                                ** **                                   *                                       **     *  *               *                                                                                             ***                  *                                                                                                              *   * ** ***  *         *     *  *       * ***                  *                 *     *      *  *                    * * ***                *  ** *   **             *  *        *       * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8337] PF05005            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Ocnus:Janus/Ocnus family (Ocn  --1----------------------------------------------------------------- -------------------------------------1---------------1-------------------------------1--------------------1----------1---------------------------------------------------------------------------11-111---111211--------1------------------------------------------------------------------------------------------------------------1--1-11-1-1---------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------11------1-------------1-------------------------------------------------------------------------------------------------------------1--1--1------------------1----------------------------------------------------------------------------1------------------------------------------------------------------- ----121-----11--------------1-----------------32--------1---------------------------------1---3--1------------222212-1-1-12211-224-1-122----1-113-111----1-422211-1212161112121-2211111221----1121----2
 us)                              *                                                                                                       *               *                               *                    *          *                                                                           ** ***   ******        *                                                                                                            *  * ** * *               *                                                                                                                                                                                               *                                                                     **      *             *                                                                                                             *  *  *                  *                                                                            *                                                                        ***     **              *                 **        *                                 *   *  *            ****** * * ***** *** * ***    * *** ***    * ****** ************* **********    ****    *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8338] PF09956            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2190:Uncharacterized conse  -----1----------------------------1--------------------------------- ---------------1--------------------1----------------1--------1------1---------------1--------11---11---1-----------------------------------111-----------11---------------------------------1-----------------------------------------------------------------------------------1-------------------------------------------------1--1------------21----------------11-------------------1-----1---122--1-------------3------1-1-1------------1----------2-----------------1-2-------------------------------1-1---1---------1------1------------------------3111---------1------------1-----1--1--1----1------------------------------------------------1----1-111111-------------------------1-------22--1-1---4----1--12311---1-2-1-1-23---1-11-11-1-1-----------1----------1-1-------------1-1--1-1--------1------------------2---1-------------------------------------------1----------------------------1-------------------------------1-- -----------------11--------------------------1------------------------1----1--------------1-----------------31--------1--------------------------------1------------32----1-1---1-1--11-----2-12-1-----
 rved protein (DUF2190)              *                            *                                                 *                    *                *        *      *               *        **   **   *                                   ***           **                                 *                                                                                   *                                                 *  *            **                **                   *     *   ***  *             *      * * *            *          *                 * *                               * *   *         *      *                        ****         *            *     *  *  *    *                                                *    * ******                         *       **  * *   *    *  *****   * * * * **   * ** ** * *           *          * *             * *  * *        *                  *   *                                           *                            *                               *                    **                          *                        *    *              *                 **        *                                *            **    * *   * *  **     * ** *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8339] PF00509            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Hemagglutinin:Hemagglutinin    ------1-------1---------------------1-----------1------------------- -----------1-----------------------------------------------------------------------2--------------------------------------------------1-----------1-1--------------------1-----------------------222221-2-2-211-------2211----------------------------------1-------------------1---------------11111111111----------------------------1111111-1-------------1-------1---------1-------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1------------11---------------------------------------1-----------------------------------1----------------1--1------------------------------------1------------------------------------------------------1------------1----------------------------------------------------11------------------------------------------------1-----------111-------------- -----1--1-11-1--------1---1-----1-------------112212--221-1111--11---11-----1--11---1--1-------2-1----1-----11--1----------1-1-1-2-1--1--111------1----------------------4----1----1-----2211-42112----
                                      *       *                     *           *                               *                                                                       *                                                  *           * *                    *                       ****** * * ***       ****                                  *                   *               ***********                            ******* *             *       *         *                         *                                                                                                                                                                          *   *            **                                       *                                   *                *  *                                    *                                                      *            *                                                    **                                                *           ***                    *  * ** *        *   *     *             ******  *** ****  **   **     *  **   *  *       * *    *     **  *          * * * * *  *  ***      *                      *    *    *     **** *****    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8340] PF12439            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 GDE_N:Glycogen debranching en  ------1111111111----------1----------------1----11322--------111---- --2-1----------------1---1--------------------------------------------------------------11111111---1-----1-----------------1------------11-----1-1111111--11---------11122------------1-1---------------------------------------------------------------------------------------------------------------------------------------------1----------1----1111-1----1-1--1---1-----------------------------------------------------------------------------------------------------------------------------------------------------------11--------1------------------------------1---------1--111----1-----1111------11-1-32-------------------------1-----1-----------------------------1--------------2--------------------------------------------------------------------------------------11-1---------------------------1-------------------------------111----------------------------------------------------------------------------------1-- 2---1---------------2----1-1111111---1111111111-------------1-----------1-----1------------1------------111--11--------------1-1-2---1-2---------1---------------1---1--1---1--------1-------------1---
 zyme N terminal                      **********          *                *    *****        ***       * *                *   *                                                              ********   *     *                 *            **     * *******  **         *****            * *                                                                                                                                             *          *    **** *    * *  *   *                                                                                                                                                           **        *                              *         *  ***    *     ****      ** * **                         *     *                             *              *                                                                                      ** *                           *                               ***                                                                                  *   *   *               *    * *******   **********             *           *     *            *            ***  **              * * *   * *         *               *   *  *   *        *             *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8341] PF08112            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1                                  
 ATP-synt_E_2:ATP synthase eps  -------311111111-------------------------------1-2---------1-------- -1-------------------------------------------------------------------------------------------1--------------1------------------------------------1---11-----------------1-----------1-1------1-------------------1----1-----------------------------------------11----------------------------------------------------1----------------1-1---1---------------------------------------------1-----------------------------------------------------------------------------------------111--------------------------------------------------------------------------------------------1------------------------------------------------1--------------------------------------1---------------------------------------------------------------1-1-------------1---------------------------------------------------------1----------------------------------------------------------------------------------1-1-------1-----------------------1------- -3--1------1----1--------------------------1----1-1---------------------1--1----1--21-------1-----------21-------1---1-151-125-213-11213-1113-231-312112--12-2----419-------12----------------1--------
 ilon subunit                          *********                               * *         *          *                                                                                           *              *                                    *   **                 *           * *      *                   *    *                                         **                                                    *                * *   *                                             *                                                                                         ***                                                                                            *                                                *                                      *                                                               * *             *                                                         *                                                                                  * *       *                       *         *  *      *    *                          *    * *                     *  *    *  **       *           **       *   * *** *** *** ***** **** *** ******  ** *    ***       **                *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8342] PF04890            153                                                                                                                                                                                               1111                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
 DUF648:Family of unknown func  ---------------1-----------------------------------1---------------- --------------1------------------------------------------------------------------1-----------------------1----------22322111---------1-----------------------------------2----------------------------1--1-1-1------1------------------21--------------------1-------------------------------1-------------------------------------11-----1-------------------------------------1-1-----------------------------------------------------------------------------11111111---------------------------------------------------------------------------------------1----------------------------------------1-------------------1--------1-------1----2----11-------------1---------------------------------11--------1---------1---------------------------------------------------------1-------------------------------------1------------------------------1------------------------------1----------------------------1---------1----------------- -----------1-1------1------111--------1------1------1-----1----1--1----------211----1----------1-----1---3----11-1-1-----------------------1---1-----------11---2-1321--------1--1-------11-1-2--1--1--
 tion (DUF648)                                 *                                   *                               *                                                                  *                       *          ********         *                                   *                            *  * * *      *                  **                    *                               *                                     **     *                                     * *                                                                             ********                                                                                       *                                        *                   *        *       *    *    **             *                                 **        *         *                                                         *                                     *                              *                              *                            *         *                             * *      *      ***        *      *      *     *    *  *          ***    *          *     *   *    ** * *                       *   *           **   * ****        *  *       ** * *  *  *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8343] PF07673            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
 DUF1602:Protein of unknown fu  ---------------2----------------------------------------2----------- -----1-11-1--------------------------------1--------1------------11---------------1-------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1---------2----2-------------1-----1--1-----------21-1--1-----------------------------42---------------------------------------------------------2---------------011-------------------1----1--------1----------------1---2-----------------1-------------------------------------------------------------------------------1------2----1--------------------------------------------------------1---1-----------------------------------------------------------------------------------------------------1---------------------------------------------------------------- ------2--1-----------1----1-------------------1----------1---2---1---------1--------------12-111-----21-1---1-1-----1121---2-11115-2-22112-123---1--2111----1---1---1-1-1-1------118-----3241--3-1-----
 nction (DUF1602)                              *                                        *                 * ** *                                *        *            **               *                                                                               *                                                                                                                                                                                              *     *         *    *             *     *  *           ** *  *                             **                                                         *               ***                   *    *        *                *   *                 *                                                                               *      *    *                                                        *   *                                                                                                     *                                                                       *  *           *    *                   *          *   *   *         *              ** ***     ** *   * *     ****   * ***** * ***** ***   *  ****    *   *   * * * *      ***     ****  * *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8344] PF10137            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 TIR-like:Predicted nucleotide  ----------------1-------2--------1-------1----1---1------------1---- 1-1-1----------------1-----------------1----1-----------------------1-------------------------------------1-----------------1---------1-----------1-------------------1-2------------------------11111---------------------------------1-11111111111111-11--1-------------------------------------------------------------------------1111--1----------------------21--------11---------11--21-1---11----21-1------------1-1----1------1-1--------------------------------------------------------1--1---------------------------------------11-------111-------1-2--1-1----1--------1---1----2------------------------------------------------------1---111--11----11--11---1-1--1----------------------------1------2--1-------------11--------------1----11------------------------2-------------1-------------1------------------------------------------1---------111---------11-1-----------------------------------------1---1-----------1-- -1--53--2--------1------1----11-------------------1--------------------------------------------1-------------------1-------------1-----1----------11--------------11-2---------------1--------------1--
 -binding protein containing T                  *       *        *       *    *   *            *     * * *                *                 *    *                       *                                     *                 *         *           *                   * *                        *****                                 * ************** **  *                                                                         ****  *                      **        **         **  ** *   **    ** *            * *    *      * *                                                        *  *                                       **       ***       * *  * *    *        *   *    *                                                      *   ***  **    **  **   * *  *                            *      *  *             **              *    **                        *             *             *                                          *         ***         ** *                                         *   *           *    *  **  *        *      *    **                   *                                            *                   *             *     *          **              ** *               *              *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8345] PF06685            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1186:Protein of unknown fu  -------------------1---1--1------1----------1---------------1------- --1-------------------------------------------------------------------1-------1-----------11----------1------11111111111111---------2--------------1-----------------112-2----11-----------------11111--1---111-------1-----------------1------------------1------------------------------------------------------------------------2--111---------11---------------1-----2-----1----------------------------------------11-11111----------------------------------------------------------------------1---------1--------------------------------------------------1-----------------------1--1--------1-------------------------------------1------------1---2-------11------1-1----------------------------------------------------------------------------------------------------------1----11---------------------1-------------------------------------1-----1-111-----------------111--1-------------1--1-----2-------1-------------------- -2-12---2---------------1-----1-------1--11--1-----------------1-1---1----11-11--1---1--2--------------11---21-1---1--1-2-1---1-12----------1-------1-------------1-2---111-1-------1----11--------11--
 nction (DUF1186)                                  *   *  *      *          *               *          *                                                                   *       *           **          *      **************         *              *                 *** *    **                 *****  *   ***       *                 *                  *                                                                        *  ***         **               *     *     *                                        ** *****                                                                      *         *                                                  *                       *  *        *                                     *            *   *       **      * *                                                                                                          *    **                     *                                     *     * ***                 ***  *             *  *     *       *                      * **   *               *     *       *  **  *                 * *   *    ** **  *   *  *              **   ** *   *  * * *   * **          *       *             * *   *** *       *    **        **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8346] PF12293            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3625:Protein of unknown fu  ------------------------1-----1------------------------------------- ----1---21------------------------------------------------------1----------------------------------1-1----------------------------------------------1---1---------------------------------------------1------1---------------------------------------------------1-----------------------1------1--111-1-1---------1-------------------------1--------------------------------------------------1--------11------------1-11--1---------------------------------------------1---------------------------------------------11-11---------------12---1---1-----------1--------------------------------1------1-----------1------------------------1--------11------1----------------1--------------------------1--------1-------------------------------1------1-------------------1----2-111111111--------------------11-11---------------------2--------------12--------------1---------1---------------1-----------------------------------------1- ----1--------------------------------333234---11---1--------1-----------1--1--------------1----11----1--1---1-111--2---1-1----11-1---1----21-1---1---111---42-1-----111---1--------8-11--1---1-----1-1-
 nction (DUF3625)                                       *     *                                          *   **                                                      *                                  * *                                              *   *                                             *      *                                                   *                       *      *  *** * *         *                         *                                                  *        **            * **  *                                             *                                             ** **               **   *   *           *                                *      *           *                        *        **      *                *                          *        *                               *      *                   *    * *********                    ** **                     *              **              *         *               *                                         *      *                                ******   **   *        *           *  *              *    **    *  *   * ***  *   * *    ** *   *    ** *   *   ***   ** *     ***   *        * **  *   *     * * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8347] PF10667            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2486:Protein of unknown fu  -------------------------11----------------------------------------- ----------------------------------------1--1-----1--1-------------21-------------------------------------------------------------------1----------------------------------------1------------------------------------------------------1----1--1----------------------------1------------1-----------------1111111111111---------------------------------------------------------------1----------111----211-------------------------1----2---------------------------------------------------------------------1--1111-111111211111111111111211------211-----1--1--------------------------1----------------1------1--1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------1----1-------------------------1--------------------------------------------------------------------------1 ------1-11-1----------1-1--11-------1--------1-------1-------1----------------------------1--------1-1--1---2-421------1-21----1-1-1-1------2-1-1-1-11---1-----1--1-1311----1-2--1-211--111-1---1----3-
 nction (DUF2486)                                        **                                                                                  *  *     *  *             **                                                                   *                                        *                                                      *    *  *                            *            *                 *************                                                               *          ***    ***                         *    *                                                                     *  **** ************************      ***     *  *                          *                *      *  *     *                                                                                                                                                                  *                                       *    *                         *                                                                          *       * ** *          * *  **       *        *       *       *                            *        * *  *   * ***      * **    * * * *      * * * * **   *     *  * ****    * *  * ***  *** *   *    * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8348] PF03580            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Herpes_UL14:Herpesvirus UL14-  ---------------------------1-1-------------------------------------- ----------------------11-----------------------------------------1----------------------------------1-------1---------------------------------1-----------------------------1-----------------1-------------------------------------------------------------1---------------------------------------------------------------------1----------------------------------------------------------------112---------1---1-11----------1----------------------------------------1-------------------11-------------------------1------1-1-----1-----2-1--1-----------1---1-1--------------------1-------------------12----1---------1-------------------------1---------------1-------------------------------11---------------------------------1-----1---------------11--------------------------------------1---------------------1-----------------------------------------------------------11--1--------------------------------------------------- ------1-----111-111111--1----11--1111122-112111-112123--111111---------------------------22111-1-1111-1----2-21---13-1-------2-----1---------------1---------2----31-1-1-11--1---1-4-----1--11-1--23-2-
 like protein                                              * *                                                             **                                         *                                  *       *                                 *                             *                 *                                                             *                                                                     *                                                                ***         *   * **          *                                        *                   **                         *      * *     *     * *  *           *   * *                    *                   **    *         *                         *               *                               **                                 *     *               **                                      *                     *                                                           **  *                                                          *     *** ******  *    **  ******* ****** ******  ******                           ***** * **** *    * **   ** *       *     *               *         *    ** * * **  *   * *     *  ** *  ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8349] PF03777            153                                                                            1                                                               1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      
 DUF320:Small secreted domain   ----------------------------1--------------------------------------- ----8----------------------1-11---------------------837---------2-38194-----------------------1---------------------------------------1-----------------------------------------------1----------------------------------------------------------------------------------22-------------------------------------------------------------1-------------------------------------------1-------------------------------------------------------1------1--------1-------------------------------------------------------------------------------1--------------1-------2----------------------------------------------11-1---1---------------------------------1------------------------------------------------------------------------------------------------------------------------------------1-------------------33333---1---------------------------------------------------------------------------------------------------------------------- -----1------------------1-1----1-------------1-1----1----2----1------------------1-----------1--1--1-2---1--1-1--1--3----------1------1--------1--1--------1----------1--2---------1-----1--2------1-11
 (DUF320)                                                   *                                            *                      * **                     ***         * *****                       *                                       *                                               *                                                                                  **                                                             *                                           *                                                       *      *        *                                                                               *              *       *                                              ** *   *                                 *                                                                                                                                    *                   *****   *                                                                                                                            *                  * *    *             * *    *    *    *                  *           *  *  * *   *  * *  *  *          *      *        *  *        *          *  *         *     *  *      * **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8350] PF07102            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1364:Protein of unknown fu  -----------------------------1-----------------1---------1---------- ----1--1--------------------------------------------------------1-----------------------------------------------------1-------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------1---------------121-----------11-----------------------------------1---------------------1-----------------------------------------------------3-----1-1--111-11-1--11-1-12-1----------------1---------111------------------1--------1---------------------------------------------1------------------------------1--------21-111-12--11112112-13-3-1-2211111111-1-----1---1--1----1--1----12122------------------11-11------------11------------------------1------2-1--------------------------------1-1-------------------------------------------------------------------- 1---1------2-----2-----------------1-111111---1-------1-----1------1-----------------------1-------1-2--1----------------1-----1------------21----1-------1-------121-1-1-------1--------------1---1---
 nction (DUF1364)                                            *                 *         *               *  *                                                        *                                                     *                                                                                           **                                                                                                                                                 *               ***           **                                   *                     *                                                     *     * *  *** ** *  ** * ** *                *         ***                  *        *                                             *                              *        ** *** **  ******** ** * * ********** *     *   *  *    *  *    *****                  ** **            **                        *      * *                                * *                                                                     *   *      *     *                 * ******   *       *     *      *                       *       * *  *                *     *            **    *       *       *** * *       *              *   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8351] PF12553            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3742:Protein of unknown fu  -----------------------------1-------------------------------------- -------------------------1--------1----1-1----1---1--------------11-1---------------------------------------------------------------------------1--------1-------------------1-------------------------------------------------------------------------------1-----------------------------------------------------------------------------1------------------------------------------------------1----1-1--1-------1--------------1----111-111-----1-------1-----------1------1------------------------------1-12--1114---11-11111--1-111111--2---1--1--1113-1-----11-1----1--------1-2-----------2-11---------------2--------------------------------1---------------------1-----------1---------1---------------------------------------12----------11-----------------------1---------------------------1----11-----------1----1----------2----------------1-11----------222------------------------------------------------------------------- ---------1------11-------------------------1---1-1---------11----------------------------1--1-1-------------2-1-----------------------------5--11-----1--1---1-----1---212--1------1---1--641----1---2-
 nction (DUF3742)                                            *                                                                *        *    * *    *   *              ** *                                                                           *        *                   *                                                                               *                                                                             *                                                      *    * *  *       *              *    *** ***     *       *           *      *                              * **  ****   ** *****  * ******  *   *  *  **** *     ** *    *        * *           * **               *                                *                     *           *         *                                       **          **                       *                           *    **           *    *          *                * **          ***                                                                             *      **                         *   * *         **                            *  * *             * *                             *  **     *  *   *     *   ***  *      *   *  ***    *   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8352] PF06191            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF995:Protein of unknown fun  -----------------------------1----1--------------------------------- --------------------------------------1----------------------------------------1-----------1---------------------------------1---1-----------------1---1--11----------1----------------------------------------------------1-1---------1---------------------------------------------------------------------------------11---111-1--------------1------------------------------1-----------------------1----22222222222-----11---3--211111123222--1-11----11-11--------------------------------------------------------1----1-------1--------------------1-------1------------------------1-------------1--1-------------------------------------------------------------1--1------------------------1--------------------------------------1-1-1-111-21-1---------------------------------------1-------------------------------1--------------------------------------11------------------------------------------------------------------------ --------1111---1-1--------------------3-11----3---11-1----1-11-----------------1-------------1-------3---1--1------1------2211---------1----------------------2----1----1--1----1-1---1--21----1-11--1-
 ction (DUF995)                                              *    *                                                                        *                                        *           *                                 *   *                 *   *  **          *                                                    * *         *                                                                                 **   *** *              *                              *                       *    ***********     **   *  ************  * **    ** **                                                        *    *       *                    *       *                        *             *  *                                                             *  *                        *                                      * * * *** ** *                                       *                               *                                      **                                                                                 ****   * *                    * **    *   ** *    * **                 *             *       *   *  *      *      ****         *                      *    *    *  *    * *   *  **    * **  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8353] PF02084            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Bindin:Bindin                  -------------------------------1------------------------------------ ----1---------1--------------------11------1----------------------1-1--------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------1-1--1----------------1111----22221------1-----------------------------------------1-------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------- ----1---1--------------------1-------111111---1---1---1-1-1---11-2----------2--1-------------1-----12----------25--1211-24-2371426-5-517--1-1-1-----1-1-21-221-------112-1------1-141-1213-1---1-1-11--
                                                               *                                         *         *                    **      *                      * *                                                                                                                                                        *                                                                                                                                                                                                                                          *                                * *  *                ****    *****      *                                         *             *                                                                                                                                                                                                                 *                                                                                                                           *   *                    *       ******   *   *   * * *   ** *          *  *             *     **          **  **** ** ******* * ***  * * *     * * ** ***       *** *      * *** **** *   * * **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8354] PF11884            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           2                                                                                                                                                       
 DUF3404:Domain of unknown fun  -------------------------------1--------------1--1------------------ -1------------------------------------------------------------------2--------------------------------------1------------------1-----1--------------------1---------1-----1---------------------------------------1-----------------------------------------1----------1-1---------1-------------------------------------------------1-----------------------------------------------1-------1----------------1-1111--11-------1---1-----------------1---------------------------------------------1------------------------------------------------------------------------1----------1-----------------------------------------------1---------1----121-1------------------------1-----------------1-------------------1---------------1--------------------1------------------------------1-----1----------------------------------------------1---------11122222221212-----------1-1--------------------1----1---------------------------------- ----1-1----------21--------1--112-------1--1--18--11--2--11-1-------------------111------------------3-1----11---1--1-----------1-------1----------11-1----------21--------2-1--1-11--1-1-1----11------
 ction (DUF3404)                                               *              *  *                    *                                                                  *                                      *                  *     *                    *         *     *                                       *                                         *          * *         *                                                 *                                               *       *                * ****  **       *   *                 *                                             *                                                                        *          *                                               *         *    *** *                        *                 *                   *               *                    *                              *     *                                              *         **************           * *                    *    *                                       * *          **        *  ***       *  *  **  **  *  ** *                   ***                  * *    **   *  *           *       *          ** *          **        * *  * **  * * *    **      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8355] PF09962            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2196:Uncharacterized conse  -------------------------------------11111111111-1111------1------1- ---------------------------------------------------------1-----------1--------------------1------------2111-1---------------1------------------1--------------------------------------1-11-1--1-1111111212131122-----1212-----11---1--11----------------------2--------------------------------------------------------------------1--1-------1-1---------------11--------1-----------1------------------------------------------11------------1-------------------------------------------------------------------------------------------------1-----------------------------------------11-1---11---------1--1-------1-1-------------------1---1----------111-----------------------------111---------------------------------------------11------------------------------------------------------------------------------------1-1--1-1------------1------11-111------------------------------------------------------------------------------- --------------1-111------1-------1------------1-11121111111-11---------------1--------------1-------1-----------2------------1-------------------------1------------------------1117111--1------1-----1
 rved protein (DUF2196)                                              *********** ****      *      *                                                           *           *                    *            **** *               *                  *                                      * ** *  * ****************     ****     **   *  **                      *                                                                    *  *       * *               **        *           *                                          **            *                                                                                                 *                                         ** *   **         *  *       * *                   *   *          ***                             ***                                             **                                                                                    * *  * *            *      ** ***                                                                                              * ***      *       *            * *********** **               *              *       *           *            *                         *                        *******  *      *     *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8356] PF11449            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2899:Protein of unknown fu  -------------------------------------------1-------2--1-1----------- --------------2------1---1------1-----1-----------1--1---------------1----------3--------------------------2---------------1---------------------2-3-----------------1--------------1-----------111--11-2-111111-122---1-----------------------------------------1-------------1------------------1-1111111----------------------------1111111-1--2-------1----2----1--------------------------------------------------------------------------------1-------------------------1-------1-----------------------------------------1---------------1------------------------------------------1---------------1---1-----------1----------1-------------------1--1-------------1-----1------1------------------------------------------------------------------------------11111111-1----------1212---------------------------------------------1-------------11121111111111----------1---------11---------------1------------------------------------ -11-1-----11---1-----------------------1------1-------------------1--1--11-------1---------------21------1-1-21---2------------1-----------1--------1-----------1---------1-21--------------1---1------
 nction (DUF2899)                                                          *       *  * *                          *      *   *      *     *           *  *               *          *                          *               *                     * *                 *              *           ***  ** * ****** ***   *                                         *             *                  * *******                            ******* *  *       *    *    *                                                                                *                         *       *                                         *               *                                          *               *   *           *          *                   *  *             *     *      *                                                                              ******** *          ****                                             *             **************          *         **               *                                      ** *     **   *                       *      *                   *  *  **       *               **      * * **   *            *           *        *           *         * **              *   *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8357] PF12141            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1          1                                                                                                                 
 DUF3589:Protein of unknown fu  ---------------------------------------------1---------------------- ------------------------------------------------------------------------------------------------------1----------------------------------------------1------------------1---1-------------------------1-------1--------------------------------------------------------------------------------------------------------------------------------------------------1--------------1------------------------1------1------------------------------------------------------------------------------1-----------------------------1-----------------------1---------------------------------------------------1------------------------------------1-------------------------------------------------------1-------------------------1---------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1------------------ --1---4----1--2--1--2-----1---1-----1-1-1--1--3-1--------------17----89-541------89952-----5---------1------11------------------------------1----------1--------1-241---1-1--------------2-------1-----
 nction (DUF3589)                                                            *                                                                                                                             *                                              *                  *   *                         *       *                                                                                                                                                  *              *                        *      *                                                                              *                             *                       *                                                   *                                    *                                                       *                         *                                                                                 *                                                                                                             *                     *   *    *  *  *  *     *   *     * * *  *  * *              **    ** ***      *****     *         *      **                              *          *        * ***   * *              *       *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8358] PF11080            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2622:Protein of unknown fu  ----------------------------------------------1----1---------------- --------------1-----------------------------------------------1-----2------------------------1--------1--1-------------------------------------1-------1----------1------------------------------------------------------------------------------------------------------------1---------1----------------------------------------------------------------------1------------111------1------------------------------------1------------------------------------------------------------------------------------------------------------------1---------------------------1------------------------------------------------2-------------------------------------2------------------------------11--2212221222221-2222222222222222221112-----111111111111111111211112---111111-1111---------------------------------------------------------------------------1--------------------------------------------1--------------------------------------- -----------1---11------------------1------------1--------------------------1--1-------------1--------1--------1--1----------------------------------1------1-------1-1-2----1------------1----1------2-
 nction (DUF2622)                                                             *    *                               *                                               *     *                        *        *  *                                     *       *          *                                                                                                            *         *                                                                      *            ***      *                                    *                                                                                                                  *                           *                                                *                                     *                              **  ************* **********************     ************************   ****** ****                                                                           *                                            *                                                   *   **                  *            *                          *  *             *        *        *  *                                  *      *       * * *    *            *    *      * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8359] PF02285            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 COX8:Cytochrome oxidase c sub  ----------------------------------------------1-------------------2- ---------------11-----------------------1---1-1------1----111---1----------1------------11---------------1-1------------------------------1------1----------------------1----1-----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------1--------1-----1-------1-1--------------1---1111-1------111-----------------1-----------------------------------------------------1------------------------3---------------------------1------------------------------1---------1--------------------------------111------------------------------------------------------------------------------------1--------------------------------------------------------1-------------------------------------------------------------------------1-1----1111----11------------------------------------------------------ -----------1---------------1---1-----------11--------------1-----------------------------------------1------2-22224-11212312221112-3-232-12211233122---311-21-1-111--1-1-2---1---1-------1----------1--
 unit VIII                                                                    *                   *                 **                       *   * *      *    ***   *          *            **               * *                              *      *                      *    *     *                                                                                                                                                                               *  *          *        *     *       * *              *   **** *      ***                 *                                                     *                        *                           *                              *         *                                ***                                                                                    *                                                        *                                                                         * *    ****    **                                                                  *               *   *           **              *                                         *      * ***** ************** * *** ***********   *** ** * ***  * * *   *   *       *          *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8360] PF11000            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2840:Protein of unknown fu  -----------------------------------------------------1-1------------ --1---------------------1-------1---1-11-1--------------------1----1------------------------------------------------------------------1-11-----------11--------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------3--1-------2-4-1312--1----------1---1--12-312----------1--16-----4----------------66------------------------------------1121----2---1-1-----111-----1-1-2-113---11--12221--2-111--------------------------1------------------------------------------------------1---------------1-------------1--1----------1---------------------------------------------------------------------------------------------------------------11111-----1--11--------------------------------------1-1-1-1111--------------------------------------1-1----------------------- ------------------11--------------------------2---1------------------------1-------------------------1------1-1--------1-----------1---------1----------------------1-1------1---1---11-----------2-111
 nction (DUF2840)                                                                    * *               *                     *       *   * ** *                    *    *                                                                  * **           **                                                  *                                                                                                                                                                  *          *  *       * * ****  *          *   *  ** ***          *  **     *                **                                    ****    *   * *     ***     * * * ***   **  *****  * ***                          *                                                      *               *             *  *          *                                                                                                               *****     *  **                                      * * * ****                                      * *                                          **                          *   *                        *                         *      * *        *           *         *                      * *      *   *   **           * ***
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8361] PF11343            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3145:Protein of unknown fu  ---------------------------------------------------------1---------- -1-11-------1-11-11-11111111111111111111111-112111111111121121211111111-------------------------------------------------------------------------------------------------1----------1-----------------------------------------------------11111-11111111----------------------------------------------------------------------------------------------------------------------------------------------------------------1-1----1-------------1-1--------------1-----------1--------------------------------------------------1----------------------1---------11-----------1-----------------1-----1-1--111-----------------1-----------------------11----11-----1------------------------------------------------------1----------------11---------------------------1--------------------------------------------------------------1-------------------------------1------------------------------------------------------------------------------ ----------1-----1-------1-----------1111-11-----11------------------------------------------1--4--------11----3------1-------1-1-1---1-1------11-------1-------------2-2--------1-1-1----2----1--21-2--
 nction (DUF3145)                                                                        *            * **       * ** ** *********************** ***************************                                                                                                 *          *                                                     ***** ********                                                                                                                                                                * *    *             * *              *           *                                                  *                      *         **           *                 *     * *  ***                 *                       **    **     *                                                      *                **                           *                                                              *                               *                                                                                         *     *       *           **** **     **                                          *  *        **    *      *       * * *   * *      **       *             * *        * * *    *    *  ** *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8362] PF04319            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 NifZ:NifZ domain               -------------------------------------------------------------1------ ----1------------------------------------111-----------------1----------------------1---------------------1--------------------------1------------11111-12------------2122-----------------------------1---1-111-1--1---1-------------------------------------------------------------------------------------------------------------------------1------------1-----------1--------------------22122---22222--------------1-11---1------111-----22------1111-11---------11--11111--------------1-----------------1-------------------3-------22---------2-----2------2-----------------33-----------------------------------------------------1---22--1--------------------------------1-------1-1-----------------------------------1-1------------------1------------------------------------2-----------------------------2---1----------2-11----------------------------------------2-----------------------------------------------------1--- -----1------1-1--1-------------------------1-----1------1--1-1-----------------------------1---1-----1----------------1--1------------------11---1-1---11----1-----1---------3------------1---1---12---
                                                                                             *           *                                    ***                 *                      *                     *                          *            ***** **            ****                             *   * *** *  *   *                                                                                                                         *            *           *                    *****   *****              * **   *      ***     **      **** **         **  *****              *                 *                   *       **         *     *      *                 **                                                     *   **  *                                *       * *                                   * *                  *                                    *                             *   *          * **                                        *                                                     *         *      * *  *                         *     *      *  * *                             *   *     *                *  *                  **   * *   **    *     *         *            *   *   **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8363] PF03634            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      113 2        
 TCP:TCP family transcription   -----------------------------------------------------------------1-- --1-----------------------------------1-------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------1-----1--------------------------------------------------------------1--------------------------------------------------------------------------------------------1-----------1-------------------------------1--------------------------------------------------------------------------------------------------11----------------------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------1 ----2-1-------1-----------111------------11---1-------------------------1-------------1-------1------1-1----------1---------12--------------------------1----------1-113-1----1------1---6825-76---21--
 factor                                                                                          *     *                                   *                                                             *                                                                                                               *     *                                                              *                                                                                            *           *                               *                                                                                                  **                                                                      **                                                                                                                       *                                                                                                       *                                                                                                   *     * *       *           ***            **   *                         *             *       *      * *          *         **                          *          * *** *    *      *   **** **   **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8364] PF06475            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1089:Protein of unknown fu  -------------------------------------------------------------------- 11---1--------11111-11--1111111111112111-----1-----------1------1----11----------1----------------------1-------------------------------------------------1---1------------------------------------------------------1----------------1------------------------------------------------------------------------------------111---------1111111-1--------------1--1--------------------2----------------------11-111-1-11--------1-2--111---1---11----------11--1---------------------------------------------------1----222222-111122121111-1211------------------2--1-----1--------------1-1-------------------------------1--------------------------------------------------1------------------1----------------------------------------------1----------1----------1-----------------------------------------------------1--1111----1-------------------------------------------------------------------------------------------------------1-- ----------------11-----1-----1----------------1-----121---------------------1---------------1-1--1----1-----11-------------1--------------------1-------------------1-1---------1--------1-----1-1-12--
 nction (DUF1089)                                                                                    **   *        ***** **  ****************     *           *      *    **          *                      *                                                 *   *                                                      *                *                                                                                    ***         ******* *              *  *                    *                      ** *** * **        * *  ***   *   **          **  *                                                   *    ****** ************ ****                  *  *     *              * *                               *                                                  *                  *                                              *          *          *                                                     *  ****    *                                                                                                       *                   **     *     *                *     ***                     *               * *  *    *     **             *                    *                   * *         *        *     * * **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8365] PF10832            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2559:Protein of unknown fu  -------------------------------------------------------------------- --1-----------1----------------------1-1-----------------1--11------------------------1------------1----1---------------------------------------------------------11--22---1-----1-----------------------------------1-----------------------------------------1----------------------------------------------------------------------------------------------------------------------------1------11--1-----------------11-11-21-1--------------1--------------------------------------------------------------------------------------------------------------------1-------1-1--------------------------------------------------------------------------------1------------------------------11-----1111111----1111-11111111111111111--1--1111111-1111111-11-11111-------------------------------------------------1-1---------2--1-1-------------------------------------------------------------------------------------------------------1--- -----------2------1---------1----1-1-------------------2----------------------------------1-----------------1---1-----------2--616-1-313--122111----111-1-------1--1------1-----11-------112---1-----1-
 nction (DUF2559)                                                                                      *           *                      * *                 *  **                        *            *    *                                                         **  **   *     *                                   *                                         *                                                                                                                            *      **  *                 ** ** ** *              *                                                                                                                    *       * *                                                                                *                              **     *******    **** *****************  *  ******* ******* ** *****                                                 * *         *  * *                                                                                                       *               *      *         *    * *                   *                                  *                 *   *           *  *** * ***  ******    *** *       *  *      *     **       ***   *     * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8366] PF04521            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Viral_P18:ssRNA positive stra  -------------------------------------------------------------------- ------------------------1------1-------------------------------------------------------------------------1------------------------------------------1-----111----------------1-----1---1------------------1--------------------------------------------------------------------------1---------------------------------------1-----------------1---1-----------------------1-----------1-----------------------1---1-11------------1-----------------------------------------------------------------------------------------------111---------1-------------1------1---------------------------------------------------------1----------------------------1----1----1--------1---------------------------------------1---------------------1---------------------------------------1----------------------------------------------------------------------------------------1--------------------------------------------------------------------- ------1-11-2---1-1-1-----1---1----------1111--11--1115-----111-1-----------21-11---------111-112---1-1-2112111-372-11111--------11---1-11-1111------1-1--21--3-12--111-1--11--1-1------3-1322-232-2----
 nd viral 18kD cysteine rich p                                                                                               *      *                                                                         *                                          *     ***                *     *   *                  *                                                                          *                                       *                 *   *                       *           *                       *   * **            *                                                                                               ***         *             *      *                                                         *                            *    *    *        *                                       *                     *                                       *                                                                                        *                                                                            * ** *   * * *     *   *          ****  **  ****     *** *           ** **         *** ***   * * ******* *** *****        **   * ** ****      * *  **  * **  *** *  **  * *      * **** *** *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8367] PF06614            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Neuromodulin:Neuromodulin      -------------------------------------------------------------------- ---------------------------1----------11--------------------1------------------------------------------------------------------------------------1-------------------------------------------------------------------------------1111--------------------------------------43-----------------------------------1------------------1------------1-------------------------------------------------------------111-11111---1-------------------------------------------------------------------------------------------------1-----------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------1-------------------------------1--1--1---------------------------1----------1------------------------------------------------------------------- ------1----1---222--3--1-1132-1------------------111-1-1--2----1----------------------------2112-----------1-2-31----2211-21641222-1-31411112211-1112-1-2112311-----11--1-------1--1--21--11------21---
                                                                                                                                *          **                    *                                                                                    *                                                                               ****                                      **                                   *                  *            *                                                             *** *****   *                                                                                                 *                                         *                                                                                                                                                      *                                                                    *                               *  *  *                           *          *                                                                          *    *   ***  *  * **** *                  *** * *  *    *                            ****           * * **    **** ******** * *********** **** * *******     **  *       *  *  **  **      **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8368] PF04604            153                                                                                                                                                                                                                                                1  1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
 L_biotic_typeA:Type-A lantibi  -------------------------------------------------------------------- --------------------------------1-------------------------------------------------------1----------1---1------111111-------------------------------3-11----------------14--2-----4-----------------------------7-2-------1------1-------------------------1----------------------------------1-4111----1-1-1111111111111--------1------111-----1------111----------111----1-------------11------------------------------------1-1---------1------1-------------------------------------------------------------------------------------221-1-----------------------------------------------------------------------------1-------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------11111-------1-----------------------------------------------------1-------------------------------------------1---- -----1-----1----------------------------------1------111-------------------11-11---------1------111-12--------1----12------1-------------------------------2--1------2------1-1------1----1-1-1---4-1--
 otic                                                                                                                                *                                                       *          *   *      ******                               * **                **  *     *                             * *       *      *                         *                                  * ****    * * *************        *      ***     *      ***          ***    *             **                                    * *         *      *                                                                                     *** *                                                                             *                                     *                                                                                                                                                                *****       *                                                     *                                           *          *     *                                  *      ***                   ** **         *      *** **        *    **      *                               *  *      *      * *      *    * * *   * *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8369] PF11616            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 EZH2_WD-Binding:WD repeat bin  -------------------------------------------------------------------- ------------------------------------------1---------------------------------------------------------1--------------------------------------------------1----------------------------------------------1--------1-----1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------1----------------------------------------------------------------------2-----------------------------------1----1-------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------1-111------------------------------------------ --11----1---------1--------1-------1--------------1-------------1----------------------------1--1-1--1-------1-2328431122222832411-313182212212211221-211612222-----1-1-----------------------1--1-----
 ding protein EZH2                                                                                                                             *                                                         *                                                  *                                              *        *     *                                                                                                                                                                                                                           *                                                                                             *                                                                      *                                   *    *                                                                                                                                                             *                                                                      * ***                                             **    *         *        *       *              *             *                            *  * *  *       * ******************* ****************** *********     * *                       *  *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8370] PF11522            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Pik1:Yeast phosphatidylinosit  -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------1-----------------------------------------1-1-------------------------------1------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1-----1-----------------------------1------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------1------------56-------------------1--------1--------------------- -11111--1-----11221--------112111-----11-11---1111111111111211111111-121121221221111121112--21-1--1-112215------11-----21--112-12---------1--1--1--2----1------22-2--12-1--------1---------1-1-1--11--1
 ol-4-OH kinase Pik1                                                                                                                                                                                      *                                         * *                               *                                          *                                                                                                                                                                                                                                                                                                            *              *     *                             *                                                      *                                                                                                                                                                                           *                                  *            **                   *        *                       *****  *     *****        ******     ** **   ********************** *********************  ** *  * ******      **     **  *** **         *  *  *  *    *      ** *  ** *        *         * * *  **  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8371] PF06206            153                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CpeT:CpeT/CpcT family (DUF100  -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------1241223332222222211143333-111---1-11-----------------------------------------1-----------------------------1-------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------1--------------------------1-11-----------1-------------------------1------------------------------------------------------------1-------------------------------------21------12--1111------1-1--1-----1---------------------------------------------1--------1------------------------------------------------------1---------------------------1--1-------------------------------------------------------------------------------------------------------1------- -3-----2-----------1---------1111-----11------11-----------------1------------1----------------------11-1---33---1-1----1------112---3-1----1----1----------------1-11----22---11------1-3112-1111-----
 1)                                                                                                                                                                                                                                                   ************************* ***   * **                                         *                             *                                                                                                                         *                                                                                       *                          * **           *                         *                                                            *                                     **      **  ****      * *  *     *                                             *        *                                                      *                           *  *                                                                                                       *         *     *           *         ****     **      **                 *            *                      ** *   **   * *    *      ***   * *    *    *                * **    **   **      * **** ****     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8372] PF09651            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Cas_APE2256:CRISPR-associated  1112-2---111--1122222-22-------------1-2----1-11----21-------------- ---------------------------------------------------------------1----1-11----------1----------------------------------------------1---1-------------1----12---------1-1-------1----11---1---1--1--------------------------1-------11-------------------------------1----------1----1-------------111--1----1------------------------------------3----------1--------------1-1----1-------------------------------------------------1-------------1---------------------------------------------------------------------------------------------------------1--------1----------1------------1-1------1-------------------1---1---------1-------1--------1---1-------------------1------------------------------------------------------1----------------------------------------------1------------------------------------------------------------------------1--------------------1-----1-----------------------------------------------1--------- 1--1--1----2-----12--------------1---------1---1-1----------------------------------------1---11211--2--2-----2-11-5-------------2-----1---------------1-------1211112112------------1---2---2---1-21--
  protein (Cas_APE2256)         **** *   ***  ******* **             * *    * **    **                                                                              *    * **          *                                              *   *             *    **         * *       *    **   *   *  *                          *       **                               *          *    *             ***  *    *                                    *          *              * *    *                                                 *             *                                                                                                         *        *          *            * *      *                   *   *         *       *        *   *                   *                                                      *                                              *                                                                        *                    *     *                                               *          *  *  *    *     **              *         *   * *                                        *   *****  *  *     * ** *             *     *               *       **********            *   *   *   * **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8373] PF04439            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Adenyl_transf:Streptomycin ad  ----1-----------------------------11---------------------------1---- --------------1------------------------1-----------------------------------------------1---1-3------1-----2-1-------------------1-----------11-------1-------------------------------------1-----1111112121211122211-1111------2------1------------------1-12-------------------------1111---1--------------------------111---1-1--12-----------1-111----2--11-1---11---------------------------------------------------------11------------1------------------------------------------------1-----1---------------------------------------------------------------------1----------1-------------------------------------------------1--------1----------------------------------1--------------------------------------------------------11-----------------------------------------------1111---------1-------11-------------11-1--------------------------1--------11----------------------------------1----------1---------------------------- ----1-1-----------------------------------------1-1----------------------------1---------------3111------1---2------1-11--1111-111-1-111-11--1----1-1----111111-------1-----1---1---------1--1---------
 enylyltransferase                  *                             **                           *                   *                        *                                               *   * *      *     * *                   *           **       *                                     *     ******************* ****      *      *                  * **                         ****   *                          ***   * *  **           * ***    *  ** *   **                                                         **            *                                                *     *                                                                     *          *                                                 *        *                                  *                                                        **                                               ****         *       **             ** *                          *        **                                  *          *                                 * *                                         * *                            *               ****      *   *      * **  **** *** * *** **  *    * *    ******       *     *   *         *  *         
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8374] PF11237            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3038:Protein of unknown fu  ------1-----------1-----2--1---------------------------------------- -------------------------------------------1---------1------------------------------------------------------------------------------------11-----23222231111111111222-2222211111211111-----------11212--211211-2----1-11---------------1--------------------1---------------------------------------------------------------------------------1-1--------1------------------------------------------1--------------------------------------------------------------------------------------1----------------------------------------------------------11--------1-----------------------------------------------11-----------------------------------------------------1-----1-1----------------------------------------------------------1--------------------------------------------------------------------------------------------1----------------------------------1------------------11---------------------------------------------------- 1---1----------1---1--------------------------1--1---1--1-----------------1----------1---------------3-1-1-1-1------1-------1----2-------------11-1-2----3-2---12-211------11-1----------1-------132-1-
 nction (DUF3038)                     *           *     *  *                                                                                    *         *                                                                                    **     ******************** ****************           *****  ****** *    * **               *                    *                                                                                 * *        *                                          *                                                                                      *                                                          **        *                                               **                                                     *     * *                                                          *                                                                                            *                                  *                  **                                                     *   *          *   *                          *  *   *  *                 *          *               * * * * *      *       *    *             ** * *    * *   ** ***      ** *          *       *** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8375] PF06799            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1230:Protein of unknown fu  ------1------------1---------------------------------1---------1---- ---------------------------------------------------------------------------------1-------------------1------------------------------1------------11111111111111111111122111-11111-1111---------------------------1-----------------------------------------------------------------1----------------------------------------------------------1-2-1----------------------11---------------------1----------------------------1----------1------------------------------------------------------------------------------------------11---------1-1-1-----------------------11------------------------------------------------------------------------------4-------111--------------------------------------------------------------------1----------------------1-------------------------------------------------------1---------------1------------------1--------------------------------------11-----------------------------1----------------- ----1----------------------11--1--1--------------11-1---1----1----1-1---------1---11-1---------1-----1------22-------1-1-12-1-11-1-1-11----1111-1-111-----------1-1-11---1--1---1113111114222-2111---1-
 nction (DUF1230)                     *            *                                 *         *                                                                                      *                   *                              *            ************************** ***** ****                           *                                                                 *                                                          * * *                      **                     *                            *          *                                                                                          **         * * *                       **                                                                              *       ***                                                                    *                      *                                                       *               *                  *                                      **                             *                      *                      **  *  *              ** *   *    *    * *         *   ** *         *     *      **       * * ** * ** * * **    **** * ***           * * **   *  *   ************* ****   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8376] PF06238            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Borrelia_lipo_2:Borrelia burg  --------2-----1-------------1---1--1111-12-------------1------------ ------------------------------------------------------------------------------------1--------------1--1-----------------------1------------------------------------------------------------------------------1--1-----------1---------2-----------------1----------1-------------------------1--------1----221111--1-12----------1-3--1----11-1----------1-----1--------------------------------------------------------------------1-11------1----------------------------1---------------5----------------------------------------------------------------------------------------------2-------------------------------1---------2---------1------------1--1----------------1------------------------22--------1----1----2-1----------1---------1-------------------1---------------------1------------1----------------1--------------------------------1-----------------------------1------1861----------------1-----------------1-21-1-1---- --112-----11--11-------------1--------1---1------1--------------2-1------21---1----------------------1--3----1-1-1---------------------------1--1----------------12113----2-21--------------1-1--------
 dorferi BBR25 lipoprotein              *     *             *   *  **** **             *                                                                                                 *              *  *                       *                                                                              *  *           *         *                 *          *                         *        *    ******  * **          * *  *    ** *          *     *                                                                    * **      *                            *               *                                                                                              *                               *         *         *            *  *                *                        **        *    *    * *          *         *                   *                     *            *                *                                *                             *      ****                *                 * ** * *       ***     **  **             *        *   *      *              * *      **   *                      *  *    * * *                           *  *                *****    * **              * *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8377] PF10651            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2479:Domain of unknown fun  --------111111--------------------------1--------------------------1 -------1----------------------------------------------------------------------1---------------------1---------------------------------------11-------------------------1-1-------1--------------------1----11-----21---1--------3--121---2-1111331552612--2-1-----------122---12---3-1----------------------------------------------1-1-----1----1-11--1----------------1------------------------------------------------------------------------------------------------------------111------1-1-----------1-----------------------------------------------------------------------------------------------------------------------------------------1----1---------1--11--1-----------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------2-----------------1----------------1-----------------------------------------------11 -----1-----------------1------------------------------------------------------11-11-1------------------------12--1-----------------------1--------1--------2--1---1-12---1-----------1----11-----1-----
 ction (DUF2479)                        ******                          *                          *        *                                                                      *                     *                                       **                         * *       *                    *    **     **   *        *  ***   * *************  * *           ***   **   * *                                              * *     *    * **  *                *                                                                                                            ***      * *           *                                                                                                                                         *    *         *  **  *                                                           *                                                                                                                     *                 *                *                                               **      *                 *                                                      ** ** *                        **  *                       *        *        *  *   * **   *           *    **     *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8378] PF08908            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1852:Domain of unknown fun  ---------11--------------------------------------------------------- --------11-----------------1--1--------1------------11--1-------------------------------------------1----------------------1---------------------------------1---------1------111----1----------------------------11---1--------------------1----------------------------------------------------------------------------------------2----------------------------------------------------------------------------1-------------------11----------------1-1-----11111111---1-----------------------------------1---1-------------------------1-----1-------1--1---------------------------------------------1--------------1----------------------------1--1-11--111--1----1---11-1-------------1-11-11------------------------------11111---1-1-111111-111--1--------------------------------------1------------21-1111131111------11-1-111----1-------------------111111111111111----------1111-----------------------------------------------1-- 1--------2------------------1--------------1-11------------------------------------------1---1-1----------1----------------11--2------13----------------------1--11-1--------------------11-1-----11--1
 ction (DUF1852)                         **                                                                  **                 *  *        *            **  *                                           *                      *                                 *         *      ***    *                            **   *                    *                                                                                        *                                                                            *                   **                * *     ********   *                                   *   *                         *     *       *  *                                             *              *                            *  * **  ***  *    *   ** *             * ** **                              *****   * * ****** ***  *                                      *            ** **********      ** * ***    *                   ***************          ****                                               *   *        *                  *              * **                                          *   * *          *                **  *      **                      *  ** *                    ** *     **  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8379] PF06342            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1057:Alpha/beta hydrolase   ----------1--------------------------------------------------------- ---------------------1--1-------1-----1--------------1------------------------------1--------1-------11-1------------------------1------------------1----1---------------------------------------------------------------------------------------------------------------32---1-1--------------------------------------------------2-1---------------------------------------------12-----------------1----------------1---------------------------------------------------------------------------------------------------------------------------------------------------1--1----------1------------------------------1-----------1----------------1------1---------------------------------------------1-111---------1----1-------------------------1----1--1--------------------------------------------------------------------------------------------11-------1---------------1--------------------------1-----1----------------211--------- --11----1----------------1------1----------------1-21-331---------------------------1----111---------1-----121211-11-----------217-2-214-----------1----11--2--111121------58-7--1---1------21----3312-
 of unknown function (DUF1057)            *                                                                               *  *       *     *              *                              *        *       ** *                        *                  *    *                                                                                                               **   * *                                                  * *                                             **                 *                *                                                                                                                                                   *  *          *                              *           *                *      *                                             * ***         *    *                         *    *  *                                                                                            **       *               *                          *     *                ***            **    *                *      *                * ** ***                           *    ***         *     ****** **           *** * ***           *    **  *  ******      ** *  *   *      **    **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8380] PF12449            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3684:Protein of unknown fu  ---------------1---------------1-------------------------1---------- -------------------------------------------------------------------------------------------------------1------------------------1----------------1--1--------------------------------1----------------------------------------------------------------------------------------------------11-----------------------------------------1--------------------------------------------------------1---------------------------------------------1---------------------------------1-------------------------------1-----------------111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------1-11-1-1-------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1-------1---23211111221111111111121111222321113211111321121111---------1-------------1---12211111121122222-------1---------------1----------1------1--1------1----2-------2-211-----------1-11--82--1--
 nction (DUF3684)                              *               *                         *                                                                                                                  *                        *                *  *                                *                                                                                                    **                                         *                                                        *                                             *                                 *                               *                 ***                                                                                                                                                                                                  *            * ** * *             *                                                                                                                                                                            *       *   **************************************************         *             *   *****************       *               *          *      *  *      *    *       * ***           * **  **  *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8381] PF04210            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 MtrG:Tetrahydromethanopterin   -------------------1------------2121111111111111111112-------------- -------------1---------------------------------------------------------------------------------------------------------------------------------1-1---11-----------------2--------1----------------------------1----------------------------111-111----1--------------------------------------------------------------------------------------12-1----------------------1-1--1---1---1----------2------------1----------1------------1-------11----1--------------------------------------------------------------1---------1--------------------1-------1--------------------------------------1----------------------1-------------1--------------------------1-------1----------------1-----------------------------1---------------------------1---------2-------------1----1---------------1---------------1---1-----------------------------------------------------1-----------------------1--2-----------------------1-1-----------1-111---- ----11--1--------------------1-------1-1111---1---------1---------1---1----------------------------------1---241-------1--1--2-2-1-1-114---2-1121-1---1-1-----11-11-----1-1--------51----1121----------
 S-methyltransferase, subunit                      *            **********************                            *                                                                                                                                 * *   **                 *        *                            *                            *** ***    *                                                                                      ** *                      * *  *   *   *          *            *          *            *       **    *                                                              *         *                    *       *                                      *                      *             *                          *       *                *                             *                           *         *             *    *               *               *   *                                                     *                       *  *                       * *           * ***         **  *                    *       * ****   *         *         *   *                                  *   ***       *  *  * * * * ***   * **** *   * *     ** **     * *        **    ****          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8382] PF10976            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    1                                                                                                                                                                                                                                                                                                              
 DUF2790:Protein of unknown fu  -------------------1------------------------------------------------ -------------------------------------------------------------1--------------------------------------------------------------------------------------1-----------------11----------------------1---1-11----1-----------11---------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------1----------------------------------------------------------1----------------------------------------------------------1---------------------------------------------------------------------------1----------------------------------------1-------1-------------------------------------7144665385778703322-------------1--------------------1111---------------------------------------------------------1-- --11-1---------111--------------------------------------------1------11----1-----111------1-1------------1------2------------------------1--------------------------11----------21-----------12-1------
 nction (DUF2790)                                  *                                                                                                              *                                                                                      *                 **                      *   * **    *           **                                                                     *                                                                                                                                                                                                                         *             *                                                          *                                                          *                                                                           *                                        *       *                                     *******************             *                    ****                                                         *     ** *         ***                                            *      **    *     ***      * *            *      *                        *                          **          **           ** *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8383] PF06956            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 RtcR:Regulator of RNA termina  --------------------11---------------------------------------------- -1----------------------------------------------------------------1------------------------------------------------------------------1----11-----------1--11-------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-------------1--------------------------------1----1--------------------1---------------------------------------------------1----111111---------------1----------1-----121-1---1----1-----------------1-----------------11-----12-------------------------------1------1---------2------------------------1-2---1111111111-11111111111-2111111-1--1-----1-1-1--1--1--1-11-111-----------------1------------4-------1------------1--------1111111-1------------------------------11-------------------------------1------------------------------------------ 1---------------------------1--1-----------1-------1----------------1------------------------------1---111---22---1------1--45-1------2----11--11-----3----2----111--2----1-------------1---------1----
 l phosphate cyclase                                **                                                *                                                                *                                                                  *    **           *  **             *                                                                                                                                                                                                          * *             *                                *    *                    *                                                   *    ******               *          *     *** *   *    *                 *                 **     **                               *      *         *                        * *   ********** *********** ******* *  *     * * *  *  *  * ** ***                 *            *       *            *        ******* *                              **                               *                                           *                           *  *           *       *                *                              *   ***   **   *      *  ** *      *    **  **     *    *    ***  *    *             *         *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8384] PF11844            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3364:Domain of unknown fun  ---------------------11-1------------------------------------------- -1---------------------------------------111--------------------1------------------------1-------1------------------------------------------------12111-11------------2111------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------1------1---------------------1----------21111---11111--------------1--1---1------2221111111------1111------------11--111----------------------------------1-------------------1-------11---------1-----1------1-----------------11---------------211111111--11---1-1-----1-------------1---11--1--------------------------------1---------1-----------------------------------1-1-------------------------------------------------------1----------1---------1-1111---1--------------1-------------------------------------------2---------------1-------------------------------------1--- -3111---1--211--111---------------------------11-1-----------1---------------------------1--1----------1-----------2------1----------------2-------11--------------11-3---1--------1-----1--2---111-3--
 ction (DUF3364)                                     ** *                                             *                                       ***                    *                        *       *                                                ***** **            ****                                    *                                                                                                                                         *      *                     *          *****   *****              *  *   *      **********      ****            **  ***                                  *                   *       **         *     *      *                 **               *********  **   * *     *             *   **  *                                *         *                                   * *                                                       *          *         * ****   *              *                                           *               *                                     *     ****   *  ***  ***                           ** *           *                           *  *          *           *      *                *       **              ** *   *        *     *  *   *** *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8385] PF04510            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             4                                                                            2        
 DUF577:Family of unknown func  ----------------------1-------------------1------------1----1------- ---------------------------------------------------------------------------------------------1----------------------------------1------------------1--------------------1------1----------------------1-------------------------------------------------1---1----------------------------1----------------------------------------1----------------11--1------------------1-1-----1----1---1----------------------------------------1------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------11-----------------------------------1----------------------------------------- -1---1-------1-------1--3-----------1---------12--------1-1122--1--------------1-------3--------1-----------1111-02-1-----2----1-1---1-1---1-1---1--1----1-211------12-----1--------111---1-3-41--2----
 tion (DUF577)                                        *                   *            *    *                                                                                                     *                                  *                  *                    *      *                      *                                                 *   *                            *                                        *                **  *                  * *     *    *   *                                        *                        *                                                                                                                                                                                                                                                                                                                                                                        *                             **                                   *                                           *   *       *       *  *           *         **        * ****  *              *       *        *           **** ** *     *    * *   * *   * *   *  *    * ***      **     *        ***   * * **  *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8386] PF04400            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF539:Protein of unknown fun  ------------------------11111--------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------11--------------------------------------------------------------------------------------------11------1-1------12111111------1--------1-1----------------------------------------------111111111111111111111111111111--1-----------------------------------------------111--1111---------------1---------11-111111111---1---------11111111111111111111-------111111111----1----1-------------22222222212222----------------3--------------------------------------------------------- -----------------1------------------------------------1----------------------1--------1-----------------------2--------11--------1-----------------------1----------------1----1----------1-2-----1----
 ction (DUF539)                                         *****                                                                                                                                                                                                                                                                                                                                                                                                                              *                                                                       **                                                                                            **      * *      ********      *        * *                                              ******************************  *                                               ***  ****               *         ** *********   *         ********************       *********    *    *             **************                *                                                                           *                                    *                      *        *                       *        **        *                       *                *    *          * *     *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8387] PF04642            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF601:Protein of unknown fun  ---------------------------1-----------------------1---------------- ---------------------------------------------1--------------------------------------------------------------------------------------11---------------11------------------------------------------11111------1-1------------------------1-----------------1-------------------------------------------------------------------------------------------1------------------------1-------3--------------------1-----------1-----1----------------------1------------------------------------------------------------------------------------1---1--------1-----------------------------------------------------------1-1----------------------------------1-------------------1---11--------------------------------------------------------1-------------------------------------------1-------------1---------------1-----------1------------------------------------111------------------1-------------------------------------------------------1- ---------21-------11---1-------1-2------------1-2--11221---1-1---1------------1-111-1--------121-1-1-2--11--3342--11----1---12-1---------1--11----121111----11---1----13--1211--1-14-----7---25422---1-
 ction, DUF601                                             *                       *                                                              *                                                                                      **               **                                          *****      * *                        *                 *                                                                                           *                        *       *                    *           *     *                      *                                                                                    *   *        *                                                           * *                                  *                   *   **                                                        *                                           *             *               *           *                                    ***                  *                                                       *           **       **   *       * *            * *  *****   * *   *            * *** *        *** * * *  **  ****  **    *   ** *         *  **    ******    **   *    **  ****  * **     *   *****   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8388] PF11714            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Inhibitor_I53:Thrombin inhibi  ----------------------------111------------------------------------- -----------------11-1-----11111-------------------------------------1---------------------------------1----------------------------------------------------------------------------------------1---------------------1------1------------------------------------------------------------------------------------------------------1------------------------------------------------------1----------------------------1----1--------1------------1-----------1-----------------------------------------------------------------------------------1---11---1---------------------------------------1------------------------1--------------------------------1-----------------------------------------122-1---11-11111--1-12-111111--------------------------1111-1--------------------------------------1---------212211----------------------------------------------------------------1-------------------------------------------------------- --------------------11--2----1122---2111111---12-1---1-11-----1---1-----1--1--1--111------11--1--------1----112------1-----11--117-1-1-3---3---1--1---1-----------1221-3--111---1-1----1-1----2-----1--
 tor Madanin                                                ***                                                       ** *     *****                                     *                                 *                                                                                        *                     *      *                                                                                                      *                                                      *                            *    *        *            *           *                                                                                   *   **   *                                       *                        *                                *                                         *** *   ** *****  * ** ******                          **** *                                      *         ******                                                                *                                                                             **  *    ****   *******   ** *   * **     *   *     *  *  *  ***      **  *        *    ***      *     **  *** * * *   *   *  *   *           **** *  ***   * *    * *    *     *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8389] PF07999            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      3                                                                                                                                                                      1                     
 RHSP:Retrotransposon hot spot  -----------------------------1-----------------1--1----------------- --1-----------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------1------1-----------------------------------------------------------------------------------------------------1---------------------3----------1--------------------------------------------------------------------1-----------------------------1-------------------------------------1------------------------------------------------------------1-------1--------------------1-1-------------------------------------------------------------------------------------------1---1--------1------------1--------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- --11------7-55-11--------1----------11-11----------1------------1--1------------1-----------1--6-----------1--3-1-221-----------------------------1---------1-----121-3---1--1--14-------1--2-17-11513-
  protein                                                    *                 *  *                    *                                                                                                     *                                                                                                               *      *                                                                                                     *                     *          *                                                                    *                             *                                     *                                                            *       *                    * *                                                                                           *   *        *            *        **                                                                                                                                                                                                  *       **      * ** **        *          ** **          *            *  *            *           *  *           *  * * ***                             *         *     *** *   *  *  **       *  * ** ***** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8390] PF10445            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2456:Protein of unknown fu  ------------------------------1--1---------------------------------- ------------1------------------------1---1----1------11-------1--------1------------------1--------------2------------------1-------------------------1--------1---------------------------------------1------1--------------------------11111111111111---------22---------12-----------------------------------------------------11-------------3-------1-----1-1--------------------1--------1----------------------------------------1--1-------------1-11-----------------------------------------------------------------------------------------11-----11------1-------------------------------------1-------------1------------1------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------1------------------1--------------2--------------------------1-12----------1----------------1------------------1----------------1--- --------111---1-------------1-----------------12111211111-1-----------1----111122-----111-------111-1311----2-1----11---5----1---1-----1--------1-1----11--1---1--2--1---2--211112----1-------1----111-
 nction (DUF2456)                                             *  *                                               *                        *   *    *      **       *        *                  *              *                  *                         *        *                                       *      *                          **************         **         **                                                     **             *       *     * *                    *        *                                        *  *             * **                                                                                         **     **      *                                     *             *            *                                                                                                                              *                                         *                  *              *                          * **          *                *                  *                *            ***   *             *                 *********** *           *    ******     ***       *** ****    * *    **   *    *   *     *        * *    **  *   *  *  *   *  ******    *       *    *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8391] PF11767            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 SET_assoc:Histone lysine meth  -----------------------------------1-------------1------------------ ----------------------------------------------------------------------------------------121---------1-1--1--1--------1--------------1---------1--------------------------------------------------11-----------------------1-------------------------------------------------------------------------------------------------------------------------------------1----------------------------------11-1-------------------------1---------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1-------------------------1----------------------1------------------------------------------1-1-----------------------------1-------------------------------1---1-----------------------1----1---------------------------------------------------------1----------------------------------------------------------------------------- 12--11--------111111111121111121211111111111211112111111111111111111-1111111111111111111112-1---122---1-112-31---------------1-------------------------1--1-------1-121---------1--------1--321---1----
 yltransferase SET associated                                      *             *                                                                                                           ***         * *  *  *        *              *         *                                                  **                       *                                                                                                                                     *                                  ** *                         *                                                               *                                                                                                             *                         *                      *                                          * *                             *                               *   *                       *    *                                                         *                                                                              **  **        ****************************************************** ********************** *   ***   * *** **               *                         *  *       * ***         *        *  ***   *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8392] PF05509            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 TraY:TraY family               -----------------------------------1--------------1-1-----------1--- ----------------1--------------------1----1------------------------------------------------1----------------1-------------------1----------------1------------------1------1----------------------------------------------------------------------------------------1---1------------------------------------------------------------1------------1------1--1------------------------1-1----------1------------------------2---------------1111----------------1--------111----------------------------------------1----------1----------1-------------1--------------1--------------1-------------------1-1---------12-1----------------------------------1-------13---------------------------------1-----1-2------112---1-2-------4------1------------1----------------------------------------------------------122222-------------1-------------------21-1-----6---1----------------1------------------------------------1-------------------- --------2--------1--111-1-12111111---111211---1------------1---------1-------------------------11-2-1--12-1-2-3----2-------------2-2------------------1------2-11-1---1-----------------1-33-----1-----
                                                                   *              * *           *                    *                    *    *                                                *                *                   *                *                  *      *                                                                                        *   *                                                            *            *      *  *                        * *          *                        *               ****                *        ***                                        *          *          *             *              *              *                   * *         ** *                                  *       **                                 *     * *      ***   * *       *      *            *                                                          ******             *                   ** *     *   *                *                                    *                             *        *  *** * ********   ******   *            *         *                         ** * *  ** * * *    *             * *                  *      * ** *   *                 * **     *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8393] PF12102            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3578:Domain of unknown fun  --------------------------------------1--------1--1----------1------ -----------1---------1---------------1--------------------------1------------------------211-------------1-------------------------1--------------11------------------------------1-------------122222-111111112-2----121112-------1--1--1121111-133111--1-----------------------1-----------------------------------------------1-----111-----------1----------1--1----1--1-1-----1-------------------------------------11111111--------------------------------------------------------------------------------------------1--------1------1----2----1-------------------------------------------------------1-----------------1-----------1--------------------1------------------------------------1---1------------------1111111-------------------------------------------------------------------------------111-1------11111-1-1----1-----1------1----1-----1----------1-----------11--------------1--------------------------------------- -1--1---------------1-1---------------1--11----1---1----------------------------1--------------------2---1--1-1--------------------------------------1----------------1---111-----1---------------111--
 ction (DUF3578)                                                      *        *  *          *                  *         *               *                          *                        ***             *                         *              **                              *             ****** ********* *    ******       *  *  ******* ******  *                       *                                               *     ***           *          *  *    *  * *     *                                     ********                                                                                            *        *      *    *    *                                                       *                 *           *                    *                                    *   *                  *******                                                                               *** *      ***** * *    *     *      *    *     *          *           **              *                                         *  *               * *               *  **    *   *                            *                    *   *  * *                                      *                *   ***     *               ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8394] PF12095            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3571:Protein of unknown fu  -------------------------------------------1------------------------ -------------------------------------------------------------------------------------------1----------1--1-----------------------1--1---11-------2111111111111111111211111221111121111--------------------------1-------------1---------1---------------------------------------------1----------------------------------11---1-1---------------------------------------------------------------------------------------------1---1---------------1----------------------------------------------------------------------1111----------------------------------------1----1--------------------------------------------------------1--------------1------------------1---------------------------------------------------------------------11-1------------------------1--------------------------------------------1---------1----------11--------------------11111------------------------------------1-------1---------------------------------- -------------1---1--1-----------1-1------------1--1111--1----------------1-------11--11---3--1--1--1------1-1--1---121-1-11----1-2-----2-2-------111--12111-1--1-1113------1-------------1111-13--1--1-
 nction (DUF3571)                                                          *                                                                                                                    *          *  *                       *  *   **       *************************************                          *             *         *                                             *                                  **   * *                                                                                             *   *               *                                                                      ****                                        *    *                                                        *              *                  *                                                                     ** *                        *                                            *         *          **                    *****                                    *       *                                                *   *  *           * *            *  ****  *                *       **  **   *  *  *  *      * *  *   *** * **    * *     * *       ***  ***** *  * ****      *             **** **  *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8395] PF06277            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 EutA:Ethanolamine utilisation  ---------------------------------------------------1---------------- ------------------------------------------1-------------------1------2----------------------------------1-----------------------------1----------------------------------1----------------------1-----------------11-1------2-1-1111111---------------------------------------------------------------------------------1----------11-------------111-11-11---11---11-2-----1-----11-1-----------------------------------------------1--------------1----------------------1-----------------1-1---------------------------------------------1------1-1-------1-------------------------------1----------------------------------------------------------1--------------------------------------1----1-1111111111-11111-1111111111111111--11-112211111111112---1-1-11----------------------------------------------------------------1------------------------------------------------------------------------------------------------------------- -----1---1--1-1----------------------------1-------1-1---1-----------1----------------------------------------2--1----111-----------------2---1--12----1111-1-2---121----1------1--------3----1-11---1-
  protein EutA                                                                     *                                                           *                   *      *                                  *                             *                                  *                      *                 ** *      * * *******                                                                                 *          **             *** ** **   **   ** *     *     ** *                                               *              *                      *                 * *                                             *      * *       *                               *                                                          *                                      *    * ********** ***** ****************  ** ***************   * * **                                                                *                                                                                                                   *   *  * *                            *       * *   *           *                                        *  *    ***                 *   *  **    **** * *   ***    *      *        *    * **   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8396] PF11805            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3326:Protein of unknown fu  --------------------------------------------------------1----------- ---------------------------------111-1------------------------------------------1---------------------1----------------------------------------1-1111111121111111111111112111111111111--------------------------------1-----1---------------------------------------------------------111-----------------------------------------------------------------------------1--------1-------------------1----------------------------------------------------------1-------------------------------------------------1-----11-------1111111-1111-1--1-------------------------------------------1----------------1-----------11-----------------------1-1--------------------1---------------------------------------------------------------1----------------------------2---11------------------------------------------------1-----------1---------1------------------------------------------1------------------------------------------------------ -----------1-----1-----------------1-------111----------1--111---------------------------1-2-111------------1-----------111------3-1-1-1--1-112-12111-2---------------4----3---1----11---2211--4--32---
 nction (DUF3326)                                                                       *                                             *** *                                          *                     *                                        * *************************************                                *     *                                                         ***                                                                             *        *                   *                                                          *                                                 *     **       ******* **** *  *                                           *                *           **                       * *                    *                                                               *                            *   **                                                *           *         *                                          *                                                                  *     *                 *       ***          *  ***                           * * ***            *           ***      * * * *  * *** ***** *               *    *   *    **   ****  *  **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8397] PF00236            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Hormone_6:Glycoprotein hormon  --------------------------------------------------------1----------- ----1------------------------------------1-1----------------------------------------------------------1-------------------------------------111---1-------------------11---1--------------------------------------1--1-----1--------------------------------------------------------------------------1--------------------------------------------11---1--------------------------------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------1--------1-------------------------------------------------------------------1---------------1----1--------------------------------------------------------------1---1------------------------------------1--1---------------2--------------------------------------------------------------------314------------2--------------------------------------------------- -1--------1-75------1---1-------------1--11---11-----1-----11--1------------1-1------------1---------1---------3131321-1211-21-1-1-2-12221111-121112211211231211----21--2-----2-1---11---1114---1------
 e                                                                                      *                *                                    * *                                                          *                                     ***   *                   **   *                                      *  *     *                                                                          *                                            **   *                                                                                **                                                                                                                                   *        *                                                                   *               *    *                                                              *   *                                    *  *               *                                                                    ***            *                                                     *        * **      *   *             *  **   **     *     **  *            * *            *         *         ******* **** ** * * * ******** ******************    **  *     * *   **   ****   *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8398] PF07460            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                1           1                      
 NUMOD3:NUMOD3 motif            -------------------------------------------------------------------- 1--------------------------------------------------------------------------------------------1---------------------------------------------------------4---------------------------1---1---------3-333-1---13--1------------1--------------------------------------------------------------1-----------------------------------------------1-------------------1--------------------1--1--------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-----------------------------------------1------------ 1---1---1---111--1--111------1---1-1-----------7-1-------1--------------1------2------1------------------2--2------------------2---------------2-------------------121----------6--211--26114-3-22-----
                                                                                                     *                                                                                            *                                                         *                           *   *         * *** *   **  *            *                                                              *                                               *                   *                    *  *              *                                                                                                                                                                                                                       *                                                                                                                                                                                                                                                            **                                         *             *   *   *   ***  *  ***      *   * *           * *       *              *      *      *                  *  *                  *               *                   ***          *  ***  ***** * **     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8399] PF10614            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Tafi-CsgF:Curli production as  -------------------------------------------------------------------- 1-----------------------------------------------1---------------------------------------------------1------------------------------------------------------1-------------------------------------11--------------------------------------------------------------------------------------1---11----1-----------------------------------------------------------1------------------------------------2---2-1----------------1-1-1-1---------1----------------------------------------------------------------------1-----------1-------------11-1-1------------1----------------------1---------1--------------------------------------------------1-----2---1-1-1111111-1111111-1-1-------------1----2-1111111111-111112111111111111111---1--111-1111111111-1--11-111-----------------------------------------1--------1-1----------1-1-111111-------------111-----------------------------11-----------------------------------------------------1 --1-------1--1---------1-1-------------------11----1-1---1---2----1----------11------------1-1--------1-------21------1-------------------------------------------2--3------------------------1------1-
 sembly/transport component Cs                                                                       *                                               *                                                   *                                                      *                                     **                                                                                      *   **    *                                                           *                                    *   * *                * * * *         *                                                                      *           *             ** * *            *                      *         *                                                  *     *   * * ******* ******* * *             *    * ********** *********************   *  *** ********** *  ** ***                                         *        * *          * * ******             ***                             **                                                     *   *       *  *         * *                   **    * *   *   *    *          **            * *        *       **      *                                           *  *                        *      * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8400] PF10023            152                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2265:Predicted aminopeptid  -------------------------------------------------------------------- -1-------------1----------------------------------------------------2------------------------------------11--------------------------------------------------------------1-----------1----------------------------------1-------1-----1----------------------------------11------------------------------------------------------------2111--1-----------1------------------1-------11------1-------------------------------------1------------1------------------------------------------------------------1----------1---------------------1--1111--1112111111121--11-------------------1---1-----------------------12-------------1-1-----1-----------1---1---1111-1----1---------1--------------------------1---------1-----------1----1-----1------1-1---------------------------------1----12---------------------------1-11111111111111111----------------------------------------1-111111-------------------------------------------------- -1-1----1--1-----1---------11---1--------1-----11-1-1----------------1--------------1----------1-----11-14---1----1--1---------1-----------1------1--------1-2-1--1-1-1---1111-1---2-----11-1--2-1-----
 ase (DUF2265)                                                                                        *             *                                                    *                                    **                                                              *           *                                  *       *     *                                  **                                                            ****  *           *                  *       **      *                                     *            *                                                            *          *                     *  ****  *************  **                   *   *                       **             * *     *           *   *   **** *    *         *                          *         *           *    *     *      * *                                 *    **                           * *****************                                        * ******                                                    * *    *  *     *         **   *        *     ** * *                *              *          *     ** **   *    *  *         *           *      *        * * *  * * *   **** *   *     ** *  * *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreede