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Ranking of HM:PFM:REP : from 8601 to 8700

                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8601] PF02395            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Peptidase_S6:Immunoglobulin A  ----1----------------------------------------------1---------------- ---------------------1-----------1-1-------------------------------------------------1--------------1--------------------------------------------------------------1-----------------------------11111--1---------------1--------------1-------1-------------------------------------------------------------------------------------------1---1-----------------------------------------------------------------------------------------1-1--1------------------------------------------------------------------------------------------------------------------------------3453335----------------------------------1----3----543------------------------------------------------1----------------1---114--121--1---316--6112---------------1---------------21-63-1---------------------------------------411-----------------------------------1-1-11-1----------------------------------------------------------------------------------------- ----------------------------------------------------------------------1-----1-----------------1---------1--------1-4-------1-----------2----1-----------------1----1---1---------1--------221----------
 1 protease                         *                                              *                                      *           * *                                                 *              *                                                              *                             *****  *               *              *       *                                                                                           *   *                                                                                         * *  *                                                                                                                              *******                                  *    *    ***                                                *                *   ***  ***  *   ***  ****               *               ** ** *                                       ***                                   * * ** *                                                                                                                                                                *     *                 *         *        * *       *           *    *                 *    *   *         *        ***          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8602] PF10752            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2533:Protein of unknown fu  ------1------------------------------------------------------------- ----------------------------------------1--------11----------------1111--------1------------------------1---1--------------------------------------1-----------------------------1-------------11111111111111111-11111111111-1--------------1--------------------------------------1-----1-----------------------------------------1---111-1----------21--1-----1----------------1------11-----------------------------------1--1-------------------------------------------------------------111----1------------------111111211111111111111-11----------------------------------------------1------------------------------------------------------------1-------------1---------------------------------------------------------------------------------------------------------------------------------1-------------1-------------------1------------1-----------2--------------1------------------------------------------------------------- 1---1----------11--------------------211111---11----------------1------1--------------1-----1----------------121-------------2-2-2-1-21------------1--------11---3-1-2--111--2-----1-------------------
 nction (DUF2533)                     *                                                                                                      *        **                ****        *                        *   *                                      *                             *             ***************** *********** *              *                                      *     *                                         *   *** *          **  *     *                *      **                                   *  *                                                             ***    *                  ********************* **                                              *                                                            *             *                                                                                                                                 *             *                   *            *           *              *                                                              *   *          **                    ******   **                *      *              *     *                ***             * * * * **            *        **   * * *  ***  *     *                   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8603] PF10786            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 G6PD_bact:Glucose-6-phosphate  ------2-------------------------------11111------------------------- ------------------------------------------------------------------------------------------------------------1--------------1----1--------------------11-----------------1-----11-----111---------22112-----12---------2-------------------------------------1-------111--11-----------111-----11-------------------------11---111------1111-11--------1-1----------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111--1---------1-------------------------11------------------1-11------------1-1-----1-------1---1-----------------------------------------------------1------------------------------------------------------1-----111111-1111---------1----1---------------111--------------------------------------------------------1---------------111----------------------- 11------1----1--2--------1---1--------1-----22-1---------2-111-----------------------1------2---1----2--------1-----1----1--21--------------1--1---2---------1-111-2-1--1----------------1---------1---
  1-dehydrogenase (EC 1.1.1.49        *                               *****                                                                                                                                      *              *    *                    **                 *     **     ***         *****     **         *                                     *       ***  **           ***     **                         **   ***      **** **        * *                                  *                                                                                                                                                                                 *******  *         *                         **                  * **            * *     *       *   *                                                     *                                                      *     ****** ****         *    *               ***                                                        *               ***                        **      *    *  *        *   *        *     ** *         * ***                       *      *   *    *        *     *    *  **              *  *   *         * *** * *  *                *         *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8604] PF07373            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CAMP_factor:CAMP factor (Cfa)  -------1----------------------------1------------------1------------ --------------1------------------------1-----------------------5-----------1---------------------------------------------------------------------------1------------1---1------------------------------------------------------------------1----------------11----------------1-------111------------------1111-11111111-------------11-----------1---------42--------1-----------------------1---1---------------------------------------------------------------------------------------111----1---------------------------------------------------------1----1----1--------1-----------11-----1-----------1-----------1-1--2-------------------1-------1-------------------------------------------------------1------------------------------------------1--------------------------------------------------------------------------------------------1---------11--------------------------------------------1-1------------------------------ 1----1----1-----1-1---------------------------41-------1-----1---1-----11----------1-------1122------------1--2-512--21----1111--5---1-----211-1---11-1-1--111-121212--------1-----11--------1------1-1
                                       *                            *                  *                           *                        *                       *           *                                                                           *            *   *                                                                  *                **                *       ***                  **** ********             **           *         **        *                       *   *                                                                                       ***    *                                                         *    *    *        *           **     *           *           * *  *                   *       *                                                       *                                          *                                                                                            *         **                                            * *                               *    *    *     * *                           **       *     *   *     **          *       ****            *  * ***  **    ****  *   *     *** *   ** * *  *** ******        *     **        *      * *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8605] PF00727            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 IL4:Interleukin 4              --------111111------------------------------------------------------ --------------------------------------------------------------------1--------------------------------------------------1111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------1-----------------1----------------1-----111---1-------------------------------------------------------------------------------1111---------------------------------------------------------1------------------------------------------------------------------------------------------------------1--1---------------------------------------------------------------------------1---------------------------------------------------1----------------------------------------------111-------------1----------------------------11---------------1-------------------------------------- -1---1--1------2-------------1-----------12---1-1---1-----------------1-----------------1------------1---1--1----1-5111212-1132313-3-414211111113212111--6252-----1-211--121-------------111---1--111--
                                        ******                                                                                                                           *                                                  ****                                                                                                                                                                                                                     *        *                 *                *     ***   *                                                                               ****                                                         *                                                                                                      *  *                                                                           *                                                   *                                              ***             *                            **               *                                        *   *  *      *             *           **   * *   *                 *                 *            *   *  *    * ******* ******* * ******************  ****     * ***  ***             ***   *  ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8606] PF10816            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2760:Domain of unknown fun  --------111111------------------------------------------------------ 1-1------------------1-----------------------------1---11------------2-----------------------------------------------------1-----------1--1-----------------1---------------------------------1--11-11-------------------------------------------------------------------------------------------11-2----11-------------------------1-------------------------------------------------1-------------------1--------------------------1--1--------1-------------1----------1----1--------------------------------1-------1-11111----11111111-2121111--------12111-----11----1-11--------1---11---------------------111111-1-------------------------------------1-------------1---------1-------------------------------------------------------------------------------1------------------------111-1---------------------------1111---1-------------------11111111-12111-------------------------------------------------------------------------- -----------------------------1---------------------------------------------1--------1--------------1-11--1--2-----2-----1--------------------1111-1-----11------1---------1--------1---1-21---1-1-2111-
 ction (DUF2760)                        ******                                                       * *                  *                             *   **            *                                                     *           *  *                 *                                 *  ** **                                                                                           ** *    **                         *                                                 *                   *                          *  *        *             *          *    *                                *       * *****    ******** *******        *****     **    * **        *   **                     ****** *                                     *             *         *                                                                               *                        *** *                           ****   *                   ******** *****                                                                                                        *                                             *        *              * **  *  *     *     *                    **** *     **      *         *        *   * **   * * **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8607] PF04609            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 MCR_C:Methyl-coenzyme M reduc  ----------1---------------------3232333332332223333333-1------------ ---------------------------------------------------------------------------------------------------------------------------------------111----11-1-1----------------------------------------------------------------1----1---------------------------------------------------------------------------------------------------------11-------111111---------------------1-------------------------------------------------1---------------------------1-------------------------1------------------------------------------------------------------------------------------1------------1----1-------------------1--------1------------11-----1-----------------------------------------------------------------2--1--11-----11-------------1----------------1--------------------------------------------------------------------------------------------------------------------------------11----------------------------------------1----------- -----1--2---11--------1-1---------------------------1----1---1-----1---1-1-----------------------------1----21-------------------2-1-2-1--------------1---------11-21---2---2-1----------1211-2--------
 tase operon protein C                    *                     ********************** *                                                                                                                                                    ***    ** * *                                                                *    *                                                                                                         **       ******                     *                                                 *                           *                         *                                                                                          *            *    *                   *        *            **     *                                                                 *  *  **     **             *                *                                                                                                                                **                                        *                 *  *   **        * *                           *    *   *     *   * *                             *    **                   * * * *              *         ** **   *   * *          **** *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8608] PF11647            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 PMT_C:C-terminal region of Pa  --------------1----------------1--------------------1----------1---- ----1-----------------------------------------------------------------------------------------1--------------------------------1----1------------------1-----------------2---------------------------------11-------1--------1----------------------------------------------------------------1--------------------------------------1------------1-----------------------1----------------------------------------------11-11-11-----------1---------1-------1------------------------------------------------------------------1----------------1-------------------------------------------------------1----1-------------------1-----------------1----------------------------------------------1-1-111-------1------1--1-------------112-----------------32-2-23-----------------------------------------------1---------------1-11------322-----------11-1111-11-22---------------------------1-----------------------------11----1---------1 -2---1------1----1------------1------------------1-------1--1--1--111------1--------1-1---1---2------1-111------------1----11--1-1-1---1--------1----1---1-22--11111-12-----1-----------12---1-1--1--6-
 steurella multocida toxin res                *                *                    *          *         *                                                                                         *                                *    *                  *                 *                                 **       *        *                                                                *                                      *            *                       *                                              ** ** **           *         *       *                                                                  *                *                                                       *    *                   *                 *                                              * * ***       *      *  *             ***                 ** * **                                               *               * **      ***           ** **** ** **                           *                             **    *         *  *   *      *    *            *                  *       *  *  *  ***      *        * *   *   *      * ***            *    **  * * *   *        *    *   * **  ***** **     *           **   * *  *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8609] PF04713            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Pox_I5:Poxvirus protein I5     ------------------1-----------1------------1--11-------------------- --2----1--------------------------------------------111--------------------1-----------------------------11-----------------------1-------------1------------------------11--------1-------------11222-32-221--11-----12----------1---1---------1-----1--------1--1-----------2------1---------------------------------------------1-1----1111-2--1------1-----------------1--------------------------------------1-----------1-------11---------------------1-------------------------------------------1-1--------------------------------------1----------------------------2131---------------------------------------------------1-----------------1----1-------------------------------------------------------------------------------1---------1-1--1-----------------1-----------------------1----------------------------------------------------1--------------------------------------------------1----------------------------1---1--- ----11----1-11----1---1-----1------------------1--1-1--1------21---------------1----1---1--1-1---------1-----1--211--------1-2--12---11--1------1-----------1-2----2221-----1----1----------1211-------
                                                  *           *            *  **                       *    *                                            ***                    *                             **                       *             *                        **        *             ***** ** ***  **     **          *   *         *     *        *  *           *      *                                             * *    **** *  *      *                 *                                      *           *       **                     *                                           * *                                      *                            ****                                                   *                 *    *                                                                               *         * *  *                 *                       *                                                    *                                                  *                            *   *        **    * **    *   *     *                  *  * *  *      **               *    *   *  * *         *     *  ***        * *  **   **  *      *           * *    ****     *    *          ****       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8610] PF10054            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2291:Predicted periplasmic  ------------------------1------------------------------------------- -------------------------------------11-----------------------1----11-------------------------------------1-1-------------------------------------1----------------1------------------------------------1----11-----1---2----1--1111-----------------------------------1---------------------------------------------------------------------1----------------------------------------2--------------1-1-----11111111112--1-------1--2---11122111--1--------------------1-1---------------------------------------1-1-1---------------------1-1-------------------1----------------------1-1-------------------------------------------------------11--1-----1-------1----------------------------11--------------------------------22221------------------------------112121121222----------------11---1----------------------------------------------------------------------------------------------------------------------------1-----111----- -------------------1---1----------1-------1---1-------------12-1---1---------------------11-----------------3-1--------------1-1-1-----21-1------1--2---11-----------1----1-1-2-2-------11----11-------
  lipoprotein (DUF2291)                                 *                                                                                 **                       *    **                                     * *                                     *                *                                    *    **     *   *    *  ****                                   *                                                                     *                                        *              * *     ***********  *       *  *   ********  *                    * *                                       * * *                     * *                   *                      * *                                                       **  *     *       *                            **                                *****                              ************                **   *                                                                                                                            *     ***                         *   *          *       *   *             ** *   *                     **                 * *              * * *     ** *      *  *   **           *    * * * *       **    **       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8611] PF09858            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2085:Predicted membrane pr  -------------------------11-----121-11----1--1----------1----------- --------------------------------------1-1----------------1------21----------------------11----------1-1----1-------------------------1-33333---1211-1---1-----------11112------------------------11111211--1-2--1-11----2---11--------1--------1---1--------1---------------------------------------------------11----------------1---211111-2-1---------1---------12----------------------------------------------------1---1-1----1-----------------------------------------------1-----------------------------1-----1------------------------------------------------1--------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1--2---------------------------1----------------1--------------1--------------------------------1--11---- --------1--1------1------11---------------------11------1---1----------------------1-----1-1-1-------1----------1---1------------------3-----------1-------1--1--------1---11-----------1-21--1-1-11---
 otein (DUF2085)                                         **     *** **    *  *          *                                                  * *                *      **                      **          * *    *                         * *****   **** *   *           *****                        ********  * *  * **    *   **        *        *   *        *                                                   **                *   ****** * *         *         **                                                    *   * *    *                                               *                             *     *                                                *                                            **                                                                                                                                                                                                               *  *  *                           *                *              *                                *  **             *  *      *      **                     **      *   *                      *     * * *       *          *   *                  *           *       *  *        *   **           * **  * * **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8612] PF11876            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3396:Protein of unknown fu  ---------------------------1---1------------------------------------ --------21---------------------------------------------------------------------------------------------------------------------------------------111--------------------1------------------------------------------------------1--------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------1113--1-----------1-------1------------------------------------------------------------1-2----21--232313-2----------1----21112--1--------------1---11-------1----1---1-------11-131----------------------------1--------------------------------------------4----------------------------------------98--1---------1-1-----------------------------------------------------------1---------11-11----1-1--111-------------------------------332-------------------------------------------------------------1-- ------1-----------1-----1-------------------1-1-----1-----21-------------------------------------1---1---------1----------------------1------------1-1-11--11----1-1--1-----12--1-------1111--1----1-11
 nction (DUF3396)                                          *   *                                             **                                                                                                                                       ***                    *                                                      *                                                              *                                                                                                                                      ****  *           *       *                                                            * *    **  ****** *          *    *****  *              *   **       *    *   *       ** ***                            *                                            *                                        **  *         * *                                                           *         ** **    * *  ***                               ***                                                             *         *           *     *                   * *     *     **                                     *   *         *                      *            * * **  **    * *  *     **  *       ****  *    * **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8613] PF12350            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CTK3_C:CTD kinase subunit gam  ------------------------------1------------------------------------- -------------------------------------------------------------------111-----------------------------1--------1----------------------------------------------------------1---------------1-------1----------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------1--------------------------------------------------1----------------2---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------- -1----------34--2111111211111221312111111111111111121122111111111111-1111111111111112-2111112211-112-41111-1-----1------------------------1-------1-----------111-11-----------1-------------1----111--
 ma CTK3 C-terminus                                           *                                                                                                         ***                             *        *                                                          *               *       *                                        *                                                                                                                                                                                                **                                                                                                        *                                                  *                *                                                                                                                                                                                                                                                                     **                                                      *          **  **************************************************** **************** ********** *** ***** *     *                        *       *           *** **           *             *    ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8614] PF09577            144                                   1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
 Spore_YpjB:Sporulation protei  --------------------------------0--------------1---------------1---- ---------------1---------1-1----------1----------------------------------------------------1------------1------------------1-------------------1--------11-------------1-1---------------------11222222212112321111111111111-2--------11-----------------------------------------------------------------------------------------------11-1-21-1------1---------------------------------------------------1--------------11111-1-----------2------------------------------------------------------1------------------------------------------------------------------------------1-1-------------------------------------1-1---------------------------------1-1------1----------1-----------------------------------------------------------------------------------------------------------------------1---------1---------------------------------------11----------11-------------------------------------------------------------------------- 1-1--4--11-----------------31---------------------------11----------1--------------------------2--------22-1-1-1--------------------------------------------------112-13--1---1----2-----1-1----21---1-
 n YpjB (SpoYpjB)                                               *              *               *                    *         * *          *                                                    *            *                  *                   *        **             * *                     ***************************** *        **                                                                                               ** * ** *      *                                                   *              ***** *           *                                                      *                                                                              * *                                     * *                                 * *      *          *                                                                                                                       *         *                                       **          **                                                                           * *  *  **                 **                           **          *                          *        ** * * *                                                  *** **  *   *    *     * *    **   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8615] PF10659            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      9                                                                                                                                                                                            
 Trypan_glycop_C:Trypanosome v  ---------------------------------1---------------------------------- -----------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------11----------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1111-1------------------------------------------------------------------------------------------ ----------9-------------------------11111--1--11--------1------------2-------------------------------1-1-----------5-------------1---------------------1----------11-4--1-------2---------1-1------1--1
 ariant surface glycoprotein C                                   *                                                                                        *                                                                                                                                                    **          **                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         * **** *                                                                                                     *                         *****  *  **        *            *                               * *           *             *                     *          ** *  *       *         * *      *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8616] PF03482            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 SIC:sic protein                -------------------------------------------------------------------- 1---1---------1------1-------------------1----------------------1-1------------------------------------------------------------------------------2----------------------------------------------------------------1-1--------------------------------------------------1----------1------1-----------------1----1---22-----111--------1------------------------1-------------------------------------1---1---------------------------1-------------------------------------------------------------------------------------------------------1--1-----11------1---1--------------------------------1-----------------------------------------------------------------------------------------------------------------2--------------1---------------------------------------------------------------------------------------1---------------------------------2------------------------------------------------------------------------------------ 1-11-------------------1-1-211-11----1212112112-2-3--111-----1----1--------------------1---1-1-3---------1--5-11121-----1---11-2-7-1--22112-11--11---11-11----2----6-111-2----1---1---11--2------1----1
                                                                                                     *   *         *      *                   *                      * *                                                                              *                                                                * *                                                  *          *      *                 *    *   **     ***        *                        *                                     *   *                           *                                                                                                       *  *     **      *   *                                *                                                                                                                 *              *                                                                                       *                                 *                                                                                     * **                   * * *** **    ********** * *  ***     *    *                    *   * * *         *  * *****     *   ** * * *  ***** **  **   ** **    *    * *** *    *   *   **  *      *    *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8617] PF09923            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2155:Uncharacterized prote  -------------------------------------------------------------------- -1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111111111111111111111111111112-111111111111111111111111-1111111111-11111111111111111-1------------1111111111111----111--1--------------------------------------------------------------------------------------111-111-------------------------------------------------------1----1-1--1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------- -1----------------1------------------------111-----------------------------1--------------1-----------------1--1-------------1---------1--------1--------11------111--2---1--11---------------2--1-----
 in conserved in bacteria (DUF                                                                        *                                                                                                                                                                                                 ***                                                                                                                                                                                 ********************************* ************************ ********** ***************** *            *************    ***  *                                                                                      *** ***                                                       *    * *  *                                                                                                                                                                                                       *                                                           *                *                        ***                             *              *                 *  *             *         *        *        **      ***  *   *  **               *  *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8618] PF10542            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           2                                                                       
 Vitelline_membr:Vitelline mem  -------------------------------------------------------------------- ---1----------------------------1----------------------------------------------------------------------------------------------------------------1----------------------1------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------1------------11-2--1------------------------------1---------------1-1---------------------------------------111111-1-------------2---------------------------------------------------------------------1----1-----------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------11-1-----21------------------------------------------------------------------------ --------11-111111--2--------------------1-------------1111---1-----------------1----------111----11--1------1-2-12-1-----1--11-5-2---21--1-----------------2--42----3-1511--28--2-3------2253-1--------
 brane cysteine-rich region                                                                             *                            *                                                                                                                *                      *                              *                                                                                                                                                                              *                     *            ** *  *                              *               * *                                       ****** *             *                                                                     *    *                                                                                         *                                                                                                                                             ** *     **                                                                                 ** ******  *                    *             ****   *                 *          ***    **  *      * * ** *     *  ** * *   **  *                 *  **    * ****  **  * *      **** *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8619] PF08748            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1789:Domain of unknown fun  -------------------------------------------------------------------- ----1-1-----1--------111-1------------1--------1---1--------------------111111--------------------------1-2-----------------------------------1----1------------------------------------------------------------1---------11--------------------------------------------------------------------------------------------------------1-----------------11-------1--1------------------------------------------------------------------------1-1------------------11111111-------------------------------------------12-1------------11--------------------1-2--2-----------1-1----1-1------1----1---------1------------------------------------------------1-------------------1---1---------------------------------------------------------2--------------------------1221-1222--1----11111--------------------------------------1--1-1--1-----1-------------1------1-1---1-----111-----------------------------------------1------1-------------- -1--21--1--------------------------------2-1------21211-------1----1---------------------1-1---1-------113---11-4----------1--------------------------1----1--------11-------------5--------1-1---2--1-
 ction (DUF1789)                                                                                         * *     *        *** *            *        *   *                    ******                          * *                                   *    *                                                            *         **                                                                                                        *                 **       *  *                                                                        * *                  ********                                           ** *            **                    * *  *           * *    * *      *    *         *                                                *                   *   *                                                         *                          **** ****  *    *****                                      *  * *  *     *             *      * *   *     ***                                         *      *                *  **  *                                * *      *****       *    *                     * *   *       ***   ** *          *                          *    *        **             *        * *   *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8620] PF11526            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 CFIA_Pcf11:Subunit of cleavag  -------------------------------------------------------------------- ---------------------------------------------1--------------------------------------------------1---1-----1------------1111--------1-----------------1----------------11--------------------------------1-------------------------------------------------------------------------------1------------------------------------------------------1--1-----1-----------------1-------1---1--------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------1-------------------------------------------1--------------------------------------------------1-------1----------------------------------------------------------------------------------------------------------------------------------1---------------------------1------------------------------------------------------------------------------------------------- --11----------121-1121211111121111211111111111211---141--11----111111211111111112112211-1--11-1------------1-3-111-1--1--1------1-----------------1-1------1---11-1--1-2112--11-----------111-1---1111-
 e factor IA Pcf11                                                                                                                                *                                                  *   *     *            ****        *                 *                **                                *                                                                               *                                                      *  *     *                 *       *   *                                                                                                                                                        *                           *                                           *                                                  *       *                                                                                                                                  *                           *                                                                                                    **          *** *******************************   ***  **    ************************ *  ** *            * * *** *  *  *      *                 * *      *   ** *  * ****  **           *** *   **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8621] PF06979            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1301:Protein of unknown fu  -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------1-1---------------------1----------------------------------------------1----------------1------------------------------------------11111112111111-----------------------------1-----------------1-----------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------1-----------------------------1---------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------- 2-----1---1---1------------------------------------11--------------------------------1-11----1---------11--11-421211-112111111-112-1-11412111111-111111--1111111-13311111222311--11-1-1112143-21-11211-
 nction (DUF1301)                                                                                                                                                                                          * *                     *                                              *                *                                          **************                             *                 *                                                                 *                                                                                                                                                                                                                                                                       *                                                            *                             *                                                                                                               *                                                                                        *     *   *   *                                    **                                * **    *         **  ** ****** ********* *** * *********** ******  ******* **************  ** * ******* ** ***** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8622] PF09425            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     1111 1        
 CCT_2:Divergent CCT motif      -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3----------------2---------------------------------------------------------------------------------------------------------------------------------------1---------1--------------------1------------------1---------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------21--------------------------------------------------2-----1----------1------------------------------------1-1- ----11---11---------11--------------------1---1-1---------1---------------1------------------1-1---1--1--1-----2-1-----21-11-----------1--1-----1-1---1-1-----1-----22----2---------1----0486-79-------
                                                                                                                                                                                                                                *                                                                                                                                                                                                                                                          *                *                                                                                                                                       *         *                    *                  *                                                                           *                                                                                                                                                       **                                                  *     *          *                                    * *      **   **         **                    *   * *         *               *                  * *   *  *  *     * *     ** **           *  *     * *   * *     *     **    *         *    **** **       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8623] PF09354            144                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 HNF_C:HNF3 C-terminal domain   -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------11-11111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------1-----------------------------------------1---1-----------265558-212-34-44-326-4-23511-14-26312--121-41-125--2-21123223--1-------------------------
                                                                                                                                                                                                                                                                                                                                                                        *                                                                                                                                           ** *****                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 *                                         *   *           ****** *** ** ** *** * ***** ** *****  *** ** ***  * ********  *                         
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8624] PF09171            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1886:Domain of unknown fun  22222211------1-1222222------------1-111111----------11111111----1-- ------------------------------------------------------------------------------------1------------------------------------------1------------1-1--------1-----------------1----------------------------------1---------1----------------------------------------1--1---1---------------------------------2---------------1------------1-------------11----1---------------11---1---1---1----------------------------------------------------1-------1-----1-1----------------------1---------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------1111-----------------------------------------------------------------------------------------------------------------------------1-----1-----------------------------------1----1------------1-------111-----------------------------------------------------1-1------------------ --------1-1----------------114----1--111111-------12-1----------1------1---1-----------1--1----1-------1-4---1--1----1--1-----11----------12--113----------111111--1---------1------------1--1---1-----
 ction (DUF1886)                ********      * *******            * ******          ********    *                                                                                       *                                          *            * *        *                 *                                  *         *                                        *  *   *                                 *               *            *             **    *               **   *   *   *                                                    *       *     * *                      *                                                                                                                                                   *                          ****                                                                                                                             *     *                                   *    *            *       ***                                                     * *                           * *                ***    *  ******       ** *          *      *   *           *  *    *       * *   *  *    *  *     **          **  ***          ******  *         *            *  *   *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8625] PF09624            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2393:Protein of unknown fu  --1------------1-------------------1-----------2------1-1-1--------- -1--21-------------------1-------------------------2----1-----1-------------------------------1-------3------------------------------------1---1--11------1---------11131------------------------------------------------1---11--------1----------------------------------------1-1---1---------------------11---1---1-------1------------1--------------------------1--------------------1--------------------------------------1----11----111111--1---------1----------------1-----------------------------------------------1111----1111-1-----1----1--1---1--------11----------1---------1---------------------------------11111----------1------------------1--------1----------------------1---1------1---------------------------------11-1-1------------------------1---------1----------------------------------------------------------1---------1-----------11----------------1-11-----------------------------------1----1------------- -----1----------------------------11-----------1--11-2------1--1-----------------11---------------------1-----41-1--1--1----------------------------1-------1-----12-11-111-1---1-----------2-2--21----
 nction (DUF2393)                 *            *                   *           *      * * *           *  **                   *                         *    *     *                               *       *                                    *   *  **      *         *****                                                *   **        *                                        * *   *                     **   *   *       *            *                          *                    *                                      *    **    ******  *         *                *                                               ****    **** *     *    *  *   *        **          *         *                                 *****          *                  *        *                      *   *      *                                 ** * *                        *         *                                                          *         *           **                * **                                   *    *                   *                            **           *  ** *      *  *                 **                     *     ** *  *  *                            *       *     ** ** *** *   *           * *  **    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8626] PF10102            143                                                     1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
 DUF2341:Domain of unknown fun  --12------11--1-21-------------1---12211112---13--011-1114-42---11-- ----------------------------------------------------------------------------------------------------121---1-----------------------------------3---------------------------------------------------------------------------------------1-------------------------11-----------------------1---------------------------------------1-------------------------------------------------1---1-----------1----12-11--------------------1-----------------------------------------------------------------------------------------------------------11----------1-----------1-11--1----------1-----4----------------5-7---1---1--1-----------------------1--------------------------1------------------------------------------------------------------------------------------------------------------1----------------------------1--11111111----------------------1-------1--11-----------------------------------------1--------1-----------------1--- ---------------------------11--------------1--11-----1--1----1-11--------------------1---------1-------------1-----------1----------------------------------------1-21---------------------1--1---11-1-
 ction (DUF2341)                  **      **  * **             *   ********   **  *** **** **   **                                                                                                       ***   *                                   *                                                                                       *                         **                       *                                       *                                                 *   *           *    ** **                    *                                                                                                           **          *           * **  *          *     *                * *   *   *  *                       *                          *                                                                                                                  *                            *  ********                      *       *  **                                         *        *                 *                               **              *  **     *  *    * **                    *         *             *           *                                        * **                     *  *   ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8627] PF11730            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3297:Protein of unknown fu  ----1------------------------------------------1------------1------- --------------1------1--11------1111---------------------------------1----------------------------------------------------------------------11----------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------1---------------1221-------11111111111------------11111111------------------11-----------11111111-1111---------------------------------11111---------------------------------------111112111-11-------------------------------------------------------------------------------11----1-1111111111111111111111-------------------------------------------------------------------------------------------1----------------------------------------------------------------------------111111111111111111111111--------------1------------------------------------------------- 1---1----------------------11-------------------------------------------------------------2----------2--11-1--2--------1-----------------------------------1----2-----1------------------1----1--------
 nction (DUF3297)                   *                                          *            *                      *      *  **      ****                                 *                                                                      **                                                                            *                                                                                                                                            *               ****       ***********            ********                  **           ******** ****                                 *****                                       ********* **                                                                               **    * **********************                                                                                           *                                                                            ************************              *                                                  *   *                      **                                                             *          *  ** *  *        *                                   *    *     *                  *    *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8628] PF09874            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2101:Predicted membrane pr  ------1----------------12--------11--------2-----1---11111111------- ------------------------------------------------------------------1-------------11---------------------1-------------------------1----1-----------1---------11---------------1----------------1--111--1211---2-1------1-1---1---11------------------------------1-----------------1-------------11111111111---------------------------------11---2-------2-1-----1-111----1--11---------------------1---1---------------------1---1----1------------1-------------------------------------------1-----------------------------------------------------1------------------------------------------------------------------------------------------------------------------------1-----------------------------1------------------------------------------------------------------------2--------------------------1----------------------------1------------------------11----------------------------------1------------------------------------1-- -1---1----21-11--------------1-112----------------1---11-1---1------1------1--------------3----1------1----1-1---11-1-------1------------------------------11--11-1-1-2-1-2-211-------1--1--1-1----111-
 otein (DUF2101)                      *                **        **        *     *   ********                                                                          *             **                     *                         *    *           *         **               *                *  ***  ****   * *      * *   *   **                              *                 *             ***********                                 **   *       * *     * ***    *  **                     *   *                     *   *    *            *                                           *                                                     *                                                                                                                        *                             *                                                                        *                          *                            *                        **                                  *                                    *    *   *    ** **              * ***                *   ** *   *      *      *              *    *      *    * *   ** *       *                              **  ** * * * * * ***       *  *  * *    *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8629] PF11503            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3215:Protein of unknown fu  --------211112---------------1------------------------------------1- --------------------------------1111-----1-----------1----------------------------------11-----------1-----------------------------------------------11----------11---111------------------------11111111-111111------1111--1--1------2--111111111111112---1----------1-------------1----------------1-1---------------------1-------------------1-------1---------------------------------------1--------------1----------------1-------------------------------------------------------------------------1----------------------------------1---------------1--------------------------1--1-----------------1----------------------------------------1-------------------------------------------1----------------------------------------1-------------------1111-------------------11111-------------------------------------------------------------------------1-1-----------------------------1-------------------------------------------1- -----4----------------2111-----------------111--1--1--11---------111--2----121121------------------1-----------------------------3----------------------------1-----11-1---1--1-1-------------11------1
 nction (DUF3215)                       ******               *                                    *                                  ****     *           *                                  **           *                                               **          **   ***                        ******** ******      ****  *  *      *  ***************   *          *             *                * *                     *                   *       *                                       *              *                *                                                                         *                                  *               *                          *  *                 *                                        *                                           *                                        *                   ****                   *****                                                                         * *                             *                                           *       *                ****                 ***  *  *  **         ***  *    ******                  *                             *                            *     ** *   *  * *             **      *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8630] PF07488            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Glyco_hydro_67M:Glycosyl hydr  ---------111-----------------1-------------------------------------- 111-1-----------------------------------1---1---1---------------11-1---------------------111-1------1--1--1---------------------------------111--------------------------------------------11-1-----------------11---------1-----------2----------11---------------------------------1-1------------------------------------------11-------------11---1--2---------11-----------1-11---1111----------------------------1-----------------1---1-----1--1--------------------------------------------------------------------------------------------------------------1--------------------1------1---------------------1----------------------------------1------------------------------------------1------------1-----------------1------------------------------------------------------------------------------------------1-------------------------------------------11111111------------------------------------------------------11-111-1-1 -----1------1--1-1211111112--1--1--1-1111------11214-311111112----------------------------2--1-------1-----1-1---------------------------1---1----------1------11----2----------1------------1--------3
 olase family 67 middle domain           ***                 *                                       *** *                                   *   *   *               ** *                     *** *      *  *  *                                 ***                                            ** *                 **         *           *          **                                 * *                                          **             **   *  *         **           * **   ****                            *                 *   *     *  *                                                                                                              *                    *      *                     *                                  *                                          *            *                 *                                                                                          *                                           ********                                                      ** *** * *      *      *  * **********  *  *  * ****      ***** *********                            *  *       *     * *                           *   *          *      **    *          *            *        *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8631] PF10865            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2703:Protein of unknown fu  ---------1-111---------11--------1-111--11--112---1---------1---1--- -----------------------------------------1-2--------1-11----21----------------------1-1----------------1----------------------------1------------1-----------------------1------------1----------------------1----------------------------------------------1-----------------------------------1---------1--------------------------------------------------------11------11-----1-21-------------------------------------------------------------------------------------------1--1----------------------------------------------11---------1---1-------------------------------------11-11--------11-----1----1------11-----------------------------1-------------------------------------------------------------------------------------1-----------------------1----------------------------1------------------------------------1-----1--1--------------------------------------1-------------------2-------------------------------1------- ----2-------75---1------------------1111111---1---1-31---------1--------------------1------1-1-----1--1-2---1-11-11------------1-2-------1--1-------------1------211-2----1---1-------------21-2---313-
 nction (DUF2703)                        * ***         **        * ***  **  ***   *         *   *                                             * *        * **    **                      * *                *                            *            *                       *            *                      *                                              *                                   *         *                                                        **      **     * **                                                                                           *  *                                              **         *   *                                     ** **        **     *    *      **                             *                                                                                     *                       *                            *                                    *     *  *                                      *                   *                               *            *       **   *                  *******   *   * **         *                    *      * *     *  * *   * ** **            * *       *  *             *      *** *    *   *             ** *   *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8632] PF10553            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 MSV199:MSV199 domain           ---------------1-----------------------1-1-------------------1------ -----------------------------------------------------------------------------------1---11-----------111-------------------------------------------1-------------------1--------------------------------1---1---1-------------11-------1---------------------1------------------------------------------------------------1-------------------------11--------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------211----------------------------1-----1---2-1----------1-------------------------1------1--------------------------------------------------------1----------------------------11111111111------------------------------------------------------------------------------------------------------------1----1--------------------------------1-1----------- -2---1----1------2-----1--------------------------1-1-----------11----2----------------1-------------1-1-2---1---21-311-11-122-2-2----211111--11-1-1121113--2111-1311-2-1--35-2--------------------7---
                                               *                       * *                   *                                                                                          *   **           ***                                           *                   *                                *   *   *             **       *                     *                                                            *                         **              *                                                                                                                                                                                                                       ***                            *     *   * *          *                         *      *                                                        *                            ***********                                                                                                            *    *                                * *             *   *    *      *     *                          * *           **    *                *             * * *   *   ** *** ** *** * *    ******  ** * *******  **** **** * *  ** *                    *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8633] PF09953            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2187:Uncharacterized prote  ---------------1--------------1-1-------1---------11------1--------- -----------------------------------------11---------------------------------------------------------------1--------------------------------------------------------------------1-----1-----1--111222222122222222-111112221111111111112---111111-111111-11111-11122111112211331-1111------------------------------------------------------------------------------1-----------------1-------------------------------------------------1-------------1-------------------------------------------------------------------------------1------------------------------------------------1---------------------------------------------------------------------------------------1---------------------1----------------------------------1------------------------------------------------1------1----1-2----------------------------------------2----------------------------------------------------------1---1---------------1---------------------- -1--2----------------------------------------------------------1----------------------------------------------------------------------------------------------------------2-1----1---------------------
 in conserved in bacteria (DUF                 *              * *       *         **      *                                                   **                                                               *                                                                    *     *     *  ****************** *********************   ****** ****** ***** ***************** ****                                                                              *                 *                                                 *             *                                                                               *                                                *                                                                                       *                     *                                  *                                                *      *    * *                                        *                                                          *   *               *                        *  *                                                          *                                                                                                          * *    *                     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8634] PF09104            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 BRCA-2_OB3:BRCA2, oligonucleo  ---------------1------------------------------------1--------------- -----------------------------------------------------1------------1--------------1------------------11------1------------------------------1--------------------------------1---------------------------------------1----------------------------------------------------------------------------1---------------------------------------------1----------------1--------------1-----------1------------------------------------1-----11-----1------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------1-----------------------------------------1--1------ -----1--21--------------------211-----------------1-------1-----------------1-1----------------2--------11-13-2-212141111133111211-1-11332111-1121121331121421----2--13312211-3-31------------1-1--1---
 tide/oligosaccharide-binding,                 *                                    *                                                                     *            *              *                  **      *                              *                                *                                       *                                                                            *                                             *                *              *           *                                    *     **     *      *                                                                                                                                                                                                      *                                                                                                                                                    *                                                                              *                                         *  *            *  **                    ***                 *       *                 * *                *        ** ** * ****************** * ******** ****************    *  ******** * **            * *  *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8635] PF09964            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2198:Uncharacterized prote  ----------------1--1---------------------------1-------------------- -1------------------------------------------------------------1------------------1--------1----------------------------------------------------1--1------------------------1-1-----1-----------11-----11-----1---11111---1111---222221-1-222122221222121111---1-1------------------1---------------------1-------1--------------------1---1-----11--------1-----2--11-1--------------1-----------------1--------------------------------------------1--1---------------------1------------------------------------------1----1----------------------------------------------------------------1-----1---------------1---1-----------------------------------1-1-----------1-------1-------------------------------------------------------1-----------------------------------1-------------------1---1----1--------------1------------------------------------------12---------------------2------------------------------------------------------ 1---------------1-----1--1-----------1-11-----12----------1----------1-----1--1-------------1-----------------2--1---1-----------1-1--------------------------1---1-4-----2-------------12-1-----1---1-
 in conserved in bacteria (DUF                  *  *                           *                      *                                                            *                  *        *                                                    *  *                        * *     *           **     **     *   *****   ****   ****** * ******************   * *                  *                     *       *                    *   *     **        *     *  ** *              *                 *                                            *  *                     *                                          *    *                                                                *     *               *   *                                   * *           *       *                                                       *                                   *                   *   *    *              *                                          **                     *                                                       *               *     *  *           * **     **          *          *     *  *             *                 *  *   *           * *                          *   * *     *             ** *     *   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8636] PF08882            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Acetone_carb_G:Acetone carbox  -----------------1-------21---11--------------------------1--------- --------------------------------1111--1---2----------1-----------1----------------1-------------------------------------------------------11-------1------------------------------1--------11-------------------1--------1------------1--------------------------------11-----------------------------------------------------------------------1-1-----------1------------------------------------------1---------------1--------11-----------1112-----1--------------------------------1----------------------1---------------------1------1---1-1--11-------2---1-----------------1-2-11--------------------1-------1-------------1-1111111-------111--------1111111-1111111-1-1----1----------------------------------------------------------------------------------------------1111111111---------------------------1--2-------------------------------1---------------------------------------------------------------------------1-1-1---- --------21-1-----1---------------1-1--1-----1-1-----1------1-1-----------------------1-----------1----------2-----121--1---------1------------------------------211-1-1-1-1--11---1--------1---1--1--1-
 ylase gamma subunit                             *       **   **                          *                                          ****  *   *          *           *                *                                                       **       *                              *        **                   *        *            *                                **                                                                       * *           *                                          *               *        **           ****     *                                *                      *                     *      *   * *  **       *   *                 * * **                    *       *             * *******       ***        ******* ******* * *    *                                                                                              **********                           *  *                               *                                                                           * * *             ** *     *               * *  *     * *     *      * *                       *           *          *     ***  *         *                              *** * * * *  **   *        *   *  *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8637] PF08181            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DegQ:DegQ (SacQ) family        ---------------------1-------1-------------------------------------- ------------------------------------------------------------1-------------------------1----1-1--------1---1------------------------------1--------2-----------------------1----------------1---11221221--1222112--1111111-------------1---------------------------------------1-----------------------------------------------------12------1--11--------1-------------------------1-----------------------------------------------------------------------------------------------1-------1------1---------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------1--------------------1----------------------------------------------------------------------------------------2-----1--------------------------------------1----------------------------11----1111-111-1---------------------------------------- 1----2--32--11--1---11-1----------------------------2-11--------1--------------------2------11---------125---11113-21-1--11-----15-21122----1----------------12-------1---12----1-----------11---1-----
                                                     *       *                                                                                                   *                         *    * *        *   *                              *        *                       *                *   ********  *******  *******             *                                       *                                                     **      *  **        *                         *                                                                                               *       *      *                                                                                                         *                                                                                      *                    *                                                                                        *     *                                      *                            **    **** *** *                                         *    *  **  **  *   ** *                            * **        *                    *      **         ***   ***** ** *  **     ** *****    *                **       *   **    *           **   *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8638] PF12188            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 STAT2_C:Signal transducer and  ------------------------1------------------------------------------- ------------------------------------------------------------------------------------------------------1---1-1------------------------------1------1--------------1-------1------------------1----------11--1---1-----------1------------------------------------------------------------------------------------------------------------------1---------------------------1-------1--1------------------------------------------1----------------------------------------------------------------------------1---1-------------2222----22221-------------------------------------------1-----------------1-----------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------11----------------2--2----------------------1-------------------------------------------------------- -1------------1---------------------------1----1-----2--------1----1-1--1--1----1--11---------1----1----------1------21212-2212226-2-224121122222122-121113------11---1----11------------2221-----1----
  activator of transcription 2                          *                                                                                                                                                  *   * *                              *      *              *       *                  *          **  *   *           *                                                                                                                  *                           *       *  *                                          *                                                                            *   *             ****    *****                                           *                 *                                                           *                                                                                                                                                      *                 **                *  *                      *                                                          *            *                           *    *     *        *    * *  *  *    *  **         *    *          *      ***** ******* * *************** ******      **   *    **            ****     *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8639] PF06670            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          1                                        
 Etmic-2:Microneme protein Etm  ------------------------2--1----------------------1----------------- -----------------11-12----11111------------1-----11------1----1----1-------------------------1--------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------1--------------------------------------------------------------1-----------------------------------------------------------------------------1-----1------------------------------------11---------------------------------11---------2--------------------------------------------------1-1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-------------------------------------------------------1 --------11-----1-1---1----1--1----------1---1---1---1-13-1-111-1-----------------------1--2------1---2--1---1-2-1---12-1----4711-------5-1-151-----1-131------5---21-21-31------221-------31---1--12--1
 ic-2                                                   *  *                      *                                   ** **    *****            *     **      *    *    *                         *                                                                                                                          *                                                                                                  *                                                              *                                                                             *     *                                    **                                 **         *                                                  * *                                                                                                                                                                                                                                               *                   *                                                       *         **     * *   *    *  *          *   *   *   * ** * *** *                       *  *      *   *  *   * * *   ** *    ****       * * ***     * ***      *   ** ** **      ***       **   *  **  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8640] PF09338            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Gly_reductase:Glycine/sarcosi  -------------------------11----------------------------------1------ --1---------------------------------------1--------------------------------------3-------------------1-----------------------------------------1-------------------------1----------------------------------------11-----------1-1111------------------------1------------------------------1--------------------------------------44--5546386-3--7----------31-----------31---1-1---1---------------1---------------------1-------------------1------------------------------------1----------------------------------------1----------------1-------1--------------1---------------------1------1----------1-11-------1-------------------------------------------------------------------------------11------------------1-------1-------------1-------------------------1---------------11-1------------------------------------------------------------111-----1------------------------------------2----------------------------------------- ---------11-----------------------------------1---------1------------------1------------------------1-------1-------------1-----12---1------1------------1----11---1-21-----1---2--------1--2----11----
 ne/betaine reductase componen                           **                                  *         *                                       *                                      *                   *                                         *                         *                                        **           * ****                        *                              *                                      **  ******* *  *          **           **   * *   *               *                     *                   *                                    *                                        *                *       *              *                     *      *          * **       *                                                                               **                  *       *             *                         *               ** *                                                            ***     *                                    *                                                   **                                   *         *                  *                        *       *             *     **   *      *            *    **   * **     *   *        *  *    **    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8641] PF07441            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 BofA:SigmaK-factor processing  ----------------------------12-1-111-------12121-1111-----111------- --------------------------------------------1-----1------------------------------------------------1-------1---------------------------------------1-------------------1-1-1-------------1----11111111111111111111111111111122-------111-1-----1--1111-----------1---------11-----------------------------------------------------1111111111111111-1111112-1-1---11111111-121221---------------------------------------1---------------------------1---------------------------------------------------------------------------------------------------1-------------------------------------------1------------------------------------------------------------------1--------------------------------------1------------------------1------------------------------------------------------------------------------------1---------------------1---------------------1-------------------------------------------------------------1------------- -----------1------------------1--------------------1-----------------------------------------------------------------1-----1-1-----------1-------------------------------1--1-----------------1-1------
  regulatory protein BofA                                   ** * ***       ***** ****     ***                                                    *     *                                                *       *                                       *                   * * *             *    ********************************       *** *     *  ****           *         **                                                     **************** ******* * *   ******** ******                                       *                           *                                                                                                   *                                           *                                                                  *                                      *                        *                                                                                    *                     *                     *                                                             *                         *                  *                    *                                                                 *     * *           *                               *  *                 * *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8642] PF10028            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2270:Predicted integral me  -----------------------------121-----------------------1----------1- ---------------------1----------1-----1-----------------------------1------1------1-----1------------------------------------------------------2----1---1-----------------------------211-----1--------1---1--1--1---------------------1--------------------------------------------------------------------------------1----------1-------------1--------------1--------------------------------11-2-1------1-1-111-11----11-2--11------11111111---1---1---------------------------------------------------1----------------------1-11----1-1----1---------------1-----------------2--------------------------11-----1---1---------------------------------------------------------------------1-------1--------------------------------------1--------------------------------------1-----1111---1--------------------------------1--1-------11----------1------------------------------1----------1---1-------------------------------1--------- ----1-2----3---------11------1111-------------1-------------11----------1--2--------------2-----------------3-1--1---11-----11-----------1------1-11111--------1-1-1-2-1-1---------------111------122--
 mbrane protein (DUF2270)                                    ***                       *          *                       *          *     *                             *      *      *     *                                                      *    *   *                             ***     *        *   *  *  *                     *                                                                                *          *             *              *                                ** * *      * * *** **    ** *  **      ********   *   *                                                   *                      * **    * *    *               *                 *                          **     *   *                                                                     *       *                                      *                                      *     ****   *                                *  *       **          *                              *          *   *                               *              * *    *         **      ****             *             **          *  *              *                 * *  *   **     **           *      * *****        * * * * * *               ***      ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8643] PF06379            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 RhaT:L-rhamnose-proton sympor  ------------------------------------1------------1------------------ 111-----------1---------------------1-11---1---------------------------------------1------21-1------2---1-1-1--------------------1-------------------------------------1-------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------1-------1-------------1-------------------------------------1-1------------------1--1------------------------------------2-------------------1----------------------------------------1-1---2----------------------1---------------------------------1------------------------------21-1------------1---------------1---------11--11-1-11111111--11111111121111111121111---1111111111111111-1111--1---11111111112-----------------------1-------------------1-------------1---------------------------------------------------1-------------------------------------------------- -----11----------------------------------1--------------1---------------------1-----------2-------------1-------------1------------------------------------1------1---1------2--1-231----1------1------
 t protein (RhaT)                                                   *            *                   ***           *                     * **   *                                       *      ** *      *   * * *                    *                                     *                                                                                                             *                                                                            *       *             *                                     * *                  *  *                                    *                   *                                        * *   *                      *                                 *                              ** *            *               *         **  ** * ********  ***********************   **************** ****  *   ***********                       *                   *             *                                                   *                                                        **                                  *              *                     *           *             *             *                                    *      *   *      *  * ***    *      *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8644] PF07509            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1523:Protein of unknown fu  ------------------------------------1------------------------------- -------------------------------------1----------------------------------------------------1--------1--1-1-1--------------------------------------11----1--------------------1---------------1--1-----------1--11--11----11--------------121-2--1-233222------------------------1----------------11111111111----------------------------------------11---1-----------------------------------11--------------------------------------------------------1111111111---------------------------------------------------------------------2--------------------------------1----------------------------------------1---------1-12--------1-1111111-------11---------------------1---------2--------------------------------------------------------------------------------------------------------------111111111111111-----------1--------------111----------------------------------1----1--------------------------1--1---------------------------- --111------------2-----------11--------------1--------11------------------------------------------------1--1--1-------------------------1---------------------11--4--------11---2------------------13--
 nction (DUF1523)                                                   *                                                                     *                                                    *        *  * * *                                      **    *                    *               *  *           *  **  **    **              *** *  * ******                        *                ***********                                        **   *                                   **                                                        **********                                                                     *                                *                                        *         * **        * *******       **                     *         *                                                                                                              ***************           *              ***                                  *    *                          *  *                               ***            *           **              *        **                                                *  *  *                         *                     **  *        **   *                  **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8645] PF12539            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Csm1:Chromosome segregation p  --------------------------------------11111------------------------- ------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1----------1------------------1-------------------------2---------------------------------------------------------------------------------------1---------------1---------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------11--1---------------------------------------1-----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------2-2-12-2---------------------------------111111---------------------1---------------------------- 1---2-1-1--1--111111111111111111111111-111111111111121111111111111111111112111111111121112--1---1--113111-------------------------------------------1----------111---1-------2--------------11----1----
 rotein Csm1/Pcs1                                                     *****                                                                                                              *                                                                                                                     *          *                  *                         *                                                                                       *               *         *                                                                                                                                                                                 *      **  *                                       *                                   *                                                                                                                                                      *                             * * ** *                                 ******                     *                             *   * * *  *  ************************ ***************************************************  *   *  ******                                           *          ***   *       *              **    *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8646] PF05484            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 LRV_FeS:LRV protein FeS4 clus  -------------------------------------------1----------------------1- ------------------1------------------1----2------------------------1---1-------------------------------1--1-----------------------------------------------11---------------------1-------1--------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------21-11---1-11---------------1--1---1-----------11-22------2131------------11---11-------------------------1---------------------2-11------121-111---------1-----1------1----------------121---------------1111--1-----------------------------------11-------------------------------------------------------------1-------------------1---------------------------------------------------------2-1--------------------1------1---------1----1-------------------------------1-------------1111------------------------------------------------1--- ----1---414---1-11---------11-1-1----1----1---2--------------1-------------1--------------1-1---111--2---------11-1-------1-111-------1-1----1---11------1---------211--1-3-----1--2-----------2-1-1--1
 ter                                                                       *                      *                    *                  *    *                        *   *                               *  *                                               **                     *       *                                *                                                                                                                                                                     ** **   * **               *  *   *           ** **      ****            **   **                         *                     * **      *** ***         *     *      *                ***               ****  *                                   **                                                             *                   *                                                         * *                    *      *         *    *                               *             ****                                                *        *   ***   * **         ** * *    *    *   *              *             *              * *   ***  *         ** *       * ***       * *    *   **      *         ***  * *     *  *           * * *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8647] PF06151            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   11 1                            
 Trehalose_recp:Trehalose rece  ----------------------------------------------1---11-----1---------- ------------------------1-----------1---------------------------------------------------211---------11-----------------------------------------------------------------------------1-----------------------1----------------------------------------------------1--------------------1------------------------------------------------------------1---------------------------------------------------1---------------------------1------------11-----------------------------------------1------------------------------------------1-------1-1--------------1--------------11-------------11------------11-------------------11111----------------------------------------------------------------------3-211-------1-1-1--1---------------------------------------------------------------------------------------------------------1--1-------------------------------------------------------11-------------------------1--------------------- 1-1-12--1-12-----------1----------------------1-------------111---------1--1--11----1--1------1---------1---1---------------1-2------------1-----------1------1---113430190--11-------------22-----2---
 ptor                                                                         *   **     *                                   *           *                                                   ***         **                                                                             *                       *                                                    *                    *                                                            *                                                   *                           *            **                                         *                                          *       * *              *              **             **            **                   *****                                                                      * ***       * * *  *                                                                                                         *  *                                                       **                         *                      * * **  * **           *                      *             ***         *  *  **    *  *      *         *   *               * *            *           *      *   *********  **             **     *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8648] PF11587            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Prion_bPrPp:Major prion prote  -----------------------------------------------------1-------------- --------------------------------------------------1-------------------------------------221--1---------------------------------------------------------1-----------------1-----------------------------1------------1--------------------------------------------1----------------------3-------------------------------------------1--------------------------------------1----1---1------------------------------1-1-------------------------------------------------------------------------------------------------------------------------1-1-2----1-1-------1------1------------------11--------1--1--------------1------11111-----------------------------1111-------------------------------1-------------------------------------2---------------------------------------------------------------1---------------------------1---------------1-------------------------------------------------------------------------------------------- ----1---1--3-----1-----1--1--1----------------2--------------1-------------1------1-1-----1----1------------2--1------1-1131111118-5-11211--1-111112211---1121-13--4-1-------2----------1--28--1-11----
 in bPrPp - N terminal                                                               *                                                                 *                                     ***  *                                                         *                 *                             *            *                                            *                      *                                           *                                      *    *   *                              * *                                                                                                                         * * *    * *       *      *                  **        *  *              *      *****                             ****                               *                                     *                                                               *                           *               *                                                                                                 *   *  *     *     *  *  *                *              *             *      * *     *    *            *  *      * ********** * *****  * *********   **** **  * *       *          *  **  * **    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8649] PF11349            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3151:Protein of unknown fu  -------------------------------------------------------------------- ----121111111111111-111111111111211111-2-1112111-111111111--11211111111--------------------------------------------------------------------1----------------1-11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------1-1--------------------------1----1------------------1---1---1-------------------------------------------------2---21----------------------------------------------12---------------------------------------------1--1-------------------------------------------------------------------------------------------1---------1--------------------------------------1--------------------------------------------------------------21---1--1------1--------1--------------1--1-11------------------------------------------------------------------- ----4-----11-----------1-1-------1--------------1--------1-----------------------------------------------2--2--------------------1-----2--------------1-----2---------------1---1-1311--3121---3-1-1---
 nction (DUF3151)                                                                                        *************** ****************** * ******* *********  ***********                                                                    *                * **                                                                                                                                                                                                  *                              * *                          *    *                  *   *   *                                                 *   **                                              **                                             *  *                                                                                           *         *                                      *                                                              **   *  *      *        *              *  * **                                                                        *     **           * *       *              *        *                                               *  *                    *     *              *     *               *   * ****  ****   * * *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8650] PF05806            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Noggin:Noggin                  -------------------------------------------------------------------- ----1------------------------------------------------------------------------------------------------------------------------------------1-------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------1-1--------------------------------------------------------------------------------------1---------------------------------------------------------11------------------------------------------------------1----------------------------------------2-------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------11-------------------------------------------------- --11-1--11----1--------1-1---1121---1--------------1--1--------------------------11-----------1---------3-----623324-11-1---11-112-1-11---11----1--21----1-54351116851-42312341---1--------1--111------
                                                                                                         *                                                                                                                                    *             *    *                                                                                                                                                                        **                                                                                                         * *                                                                                      *                                                         **                                                      *                                        *                                                                                                                                     *                                                    **                                                     ** *  **    *        * *   ****   *              *  *                          **           *         *     ****** ** *   ** *** * **   **    *  **    * *********** ********   *        *  ***      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8651] PF04737            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Lant_dehyd_N:Lantibiotic dehy  -------------------------------------------------------------------- ----4------------------------------------254----------------85-13---23-----------------------1----------3---1---------------------------11-----1---------------------1-----1------1------------1------2---------17--------111--------------1-11111---11-----------------------1--------------------1-------------11111------1------------------------------1--------------------------1------------------------------------1---------------------------------------------------------------------------------------------------2111--2-211111--1---1------------------------------------------------------------------43-----------------------------------------------------------------------------------------------------1----------------1----------------1-------1----------------------------------------------------------------1------------------------------------------------------1--------------------------------------------------- ---1--1-11-1--------1-1------1------------------------------1-----1------11----1-------------------1-------11-------------------11-----1------------1--------1----1----11--11----1--2-1--1-1---------1-
 dratase, N terminus                                                                                     *                                    ***                ** **   **                       *          *   *                           **     *                     *     *      *            *      *         **        ***              * *****   **                       *                    *             *****      *                              *                          *                                    *                                                                                                   ****  * ******  *   *                                                                  **                                                                                                     *                *                *       *                                                                *                                                      *                                                       *  * ** *        * *      *                              *     *      **    *                   *       **                   **     *            *        *    *    **  **    *  * *  * *         * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8652] PF12369            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 GnHR_trans:Gonadotropin hormo  -------------------------------------------------------------------- -------1------------------------------1-----------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1---------1------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1-------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------1-------------------------------------------------------1 --1---------1----1-------------------111-------------------1-1-------1-------------------1-----1---------1------2--322332231372215-3-62312213327212223112225431--2---1------1-1------1-----------------
 ne receptor transmembrane reg                                                                              *                              *                                                                 **                                                                                                                                                                                                                                *              *         *                                                                                                                                                                  *                                                                 *                                                                                           *                                                                                             *                                                                                       *                                                       *   *         *    *                   ***                   * *       *                   *     *         *      *  *************** * **************************  *   *      * *      *                 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8653] PF10709            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2511:Protein of unknown fu  -------------------------------------------------------------------- --------------1---------------------------------------1--------------------1------------------------------1------------------------------------------11--------------2-------------------------------------------------------------------------------------------------------1-----1-----------------------------------------------1--------------------------------------------------------------------1-------------------------1--111----11-1---------------------------------------------------------1-1----1-------1--1-1--------1----------------------------1-------------------------1-------------------------------------------------------------------11-1---1-1--1--1---------------1111-111221111111-2111111112211111111111111211111111111111111111111111-111111111111---------------1-----------------1-------------------------------------------1--11------------------------------------------------------------------------------ ----------------------1-------------1-1-------1----------------------------------------------------------1----1-1------1-----1-------------------------------------2-1-2------------------1-1----------
 nction (DUF2511)                                                                                                  *                                       *                    *                              *                                          **              *                                                                                                       *     *                                               *                                                                    *                         *  ***    ** *                                                         * *    *       *  * *        *                            *                         *                                                                   ** *   * *  *  *               **** ************ **************************************************** ************               *                 *                                           *  **                                                                                                     *             * *       *                                                          *    * *      *     *                                     * * *                  * *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8654] PF10330            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Stb3:Putative Sin3 binding pr  -------------------------------------------------------------------- --------------1-----------------------------------------------1----------------------------1--------11-----------------------------1-------------------1--------1-1------------------------------------1---11------------------------------------------------------------------------------------------------------------------------------------1---------------1------------------------1-------1-----------11-111-11-------1-----------1-12--------------------------------1------------------1-----------------1-----11-1------------------------------1---------------------------1------1-----------------------1-------------------------------1--------------1--------------------------1-----------------------------------------------------------------------------------------------------------------------------------1-----1-1------------------------------------------------------------------------------------------------------ --------1------21111111111111121111111111111113111121121111111112111111211111--2111111111---1--1-----1------1-----1------------1-1---------------------------------1------11-------1-----1-121--1------
 otein                                                                                                             *                                               *                            *        **                             *                   *        * *                                    *   **                                                                                                                                    *               *                        *       *           ** *** **       *           * **                                *                  *                 *     ** *                              *                           *      *                       *                               *              *                          *                                                                                                                                   *     * *                                                                                                               *      **************************************************************  **********   *  *     *      *     *            * *                                 *      **       *     * ***  *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8655] PF10489            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            11 1                                                                   
 RFPL3_antisense:Ret finger pr  -------------------------------------------------------------------- ---------------1111-1-----11111-------------------------------------------------------------------------------------------------------------1----1---------------------------------------------------------11----------------------------11111111111111----------------------------------------------------------------------------1---------------1-----------------------------------------------------1----------------------1----1--------------------------11111111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1-----------1----------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------- -211-------------23----1--------11-1--1----11----------------1-------1------1-----------------1---------1---2----11-2----------325-3-852----1----------1--------11---1--------1-----------11------13-1-
 otein-like 3 antisense                                                                                             **** *     *****                                                                                                             *    *                                                         **                            **************                                                                            *               *                                                     *                      *    *                          ********                                                                                                                                                                                 *      *           *                                                                                                                                  *                                                                                                                                     ***             **    *        ** *  *    **                *       *      *                 *         *   *    ** *          *** * ***    *          *        **   *        *           **      ** * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8656] PF05196            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 PTN_MK_N:PTN/MK heparin-bindi  -------------------------------------------------------------------- --------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------- ----------1------2--------1--------------1----------------------------------------------------11------------1-3552232-1221217412-2-6-4241121311431112-121115223---1-3-2-21--2------------2--2--1---2---
 ng protein family, N-terminal                                                                                                                               *                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              *                                                             *                                                                                                                                                                *                                       *      *        *              *                                                    **            * ******* ********** * * **************** *********   * * * **  *            *  *  *   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8657] PF11652            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3259:Protein of unknown fu  -------------------------------------------------------------------- ----------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------2----------------------------------------------1-11----------------------------------------------------------------------------------------1---------------------1------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------11111-11111------------------------------------------------------------1--------------------------------------------------------------------------------------------------- ----1---------1---------1---1----------------1-----1---------------------------11-----------------------1-----42423522121132522113-2-222112221221122322-1222122224-32-----1-11------------------1--11--
 nction (DUF3259)                                                                                                                                                    *                                                                                                                                                                                                                                                                                                                       *                 *                                              * **                                                                                        *                     *                                                                  *                                                                                                                         ***** *****                                                            *                                                                                                        *         *         *   *                *     *                           **                       *     ******************** * ****************** ********** **     * **                  *  **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8658] PF03868            143                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         1         1                                                               
 Ribosomal_L6e_N:Ribosomal pro  -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1-----1-1-------------------1------1----1-1----------------------------------------111-111111111-224-1--21111121-11161221712-4-12011111111111--12111-111111------2--11121-11-----114222-3--------
 tein L6, N-terminal domain                                                                                                                                                                                                                              *                                                         *                                                                                                                                                                                                                                **                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         *     * *                   *      *    * *                                        *** ********* *** *  ******** *********** * **************  ***** ******      *  ***** **     ****** *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8659] PF08901            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1847:Protein of unknown fu  11-----------------------1---------11-1111-------11111-------------- -------------------------------------------------------------------------------------------1--------------------------------11-21-11--1-----------------------------------------------------------------1------------------1----------------------------------------------------------------------------------------------------------1111-11--1-1111------1----2-111111---1-11---------------------------------------------------------------------------------------------------1-------------------------------1-------1-----------1------------------------1-----------1---------------2------11-----111-11133-----------1-----------------1-----------------------------1-----1------------11---1--221-11111-1--1111111111-------------------------------1111111-----------------------------------------------------------------------------------------------1------------------------------------------------------------------1----------- -----2----1-----------1--------------1-1-111---1---------------------------------------------------------1------------------2--2-1-------1------2---1--1-1--1------2-11-11-2------1------1-1-----------
 nction (DUF1847)               **                       *         ** ****       *****                                                                                                          *                                ** ** **  *                                                                 *                  *                                                                                                          **** **  * ****      *    * ******   * **                                                                                                   *                               *       *           *                        *           *               *      **     *** *****           *                 *                             *     *            **   *  *** ***** *  **********                               *******                                                                                               *                                                                  *                 *    *           *              * * ***   *                                                         *                  *  * *       *      *   *  * *  *      * ** ** *      *      * *           
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8660] PF12085            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3562:Protein of unknown fu  11-----------------1-----------------------------1------------------ ----2111------2------1---1------1---2123--2--1-1--------1---121---1--1-----------------------------------------------------1---1--------------------------------1-----------------------------1---------------------------------------1------------------------------------1----------------1------------------------------11------------------------------------------------------------------------1-----------------------------------1-1-------------1-11-1---------1-----------------------------------------------111111132331121334445111-1-1--112----------------------------------1-1-----1----------2----------------------------------------2------------------------------------------------------------------------------------1---------------------------------------------------------------------------------1------------------------------------------1------------------------------------------------------------------------- --------------------1------11---------1-----------1------------------------------------------1-1-----1-----------41-3---1-----------------1------------------1-----2-1-1-----------------1---------11-1
 nction (DUF3562)               **                 *                             *                       ****      *      *   *      *   ****  *  * *        *   ***   *  *                                                     *   *                                *                             *                                       *                                    *                *                              **                                                                        *                                   * *             * ** *         *                                               ************************ * *  ***                                  * *     *          *                                        *                                                                                    *                                                                                 *                                          *                                                                                              *      **         *           *                                          * *     *           ** *   *                 *                  *     * * *                 *         ** *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8661] PF04013            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF358:Protein of unknown fun  22-2-1----------2-22222111111111---1111111211111111211121111-------- --1---------------------------------------------------------1------------------------1--------------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------------------------1------------11----1------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------11--------1-------1-------------------------------------1---1111-1-------------------------------------------------------------------------------1------1-----------------------------------1---------------------------------------------1--------------11111111111--------------------------------1-----------------------------------1----- ------------2-----11--------------------------1-------------------1----------------------------2-----111----5-2-------------13-2-------------2--11------1--112---1-1---------21---22---1-2----------1--
 ction (DUF358)                 ** * *          * **************   *************************           *                                                         *                        *                                                  **                                                                                                                                          *  *                                              *            **    *            *                                                                                                                                                              *                                                               **        *       *                                     *   **** *                                                                               *      *                                   *                                             *              ***********                                *                                   *                  *     **                          *                   *                            *     ***    * *             ** *             *  **      *  ***   * *         **   **   * *          *  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8662] PF11244            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   1                                                               
 Med25_NR-box:Mediator complex  -1------------------------------------------------------------------ -----------------------------------------------------------------------------------------------------------------------------------------1-----------------------1-------------1-------11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------1------------------------------------1-2-----------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------1------------------------------------------1-----------------------------------------------------------1---------11------------------------------------------------------------------- ------------12-1-1-------1-------11-------------1-----1--1--1--1-------------------1-------------------1-----3-1-11-1----111421817-4-615-1--1-231-121-2--3-21211--1114-2-1--33--1------12-112--1---1---
  subunit 25 C-terminal NR box   *                                                                                                                                                                                                            *                       *             *       **                                                                                                                                                                                                                                         *                                                                                     *                                    * *                                                                                                                                                                       *                     *                                          *                                                           *         **                                                                                ** * *       *       **             *     *  *  *  *                   *                   *     * * ** *    ********* * *** *  * *** *** *  * *****  **** * *  **  *      ** ***  *   *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8663] PF10435            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 BetaGal_dom2:Beta-galactosida  --1------------1---------------------------------------------------- ----2----------------------------------------------------------1---21------------------------------------------------------------1--------------------------------------------1-1------------------------------------------------------1-------------------------------------------------------------------------11------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1-----------------------------------------------------1---------------------1--1----1-- 1-----------1-131244443654522----------------13411224433-1-222---------------------------3241-42-----11-------1-----11---------------------------------------1--1---11--1-1--1--------1------3---------
 se, domain 2                     *            *                                                         *                                                          *   **                                                            *                                            * *                                                      *                                                                         **                  *                                                                                                                                                                            *        *                                                                                                                                                                                                                  *                                                                                                             *                                                     *                     *  *    *   *           * ***************                *********** * ***                           **** **     **       *     **                                       *  *   **  * *  *        *      *         
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8664] PF10802            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2540:Protein of unknown fu  --1--------------------1---1-------12-26152----1--1-1--------------- -1------------------------------------------------------------------------------------1-1111------------1------------------------------------------1---------------------1---1-----11--------------------------------------------------3---------------------1--------1-----------------------------------------------------------12-11111111112---21------1---1---2-----1---1--2------------------------------------------------------------------------1--1----------------------1------------------------------------------------------------------------------------------------------------------------1-------------1---------1-----------1------------------------------------------------------------------------------------------1-1------------------------------------------------------------------------------1---------------------1-1--1-1---1-----------------------------1111--------------------------------1-----1---------2--- -1--------11------------------1-----1---------1---1-----1-1-----1-1---1-----11311----------------1---1--1----1--1----1----1---------------------------------1-1-13--231---4--11----------1--5---1------
 nction (DUF2540)                 *                    *   *       ** *****    *  * *                 *                                                                                    * ****            *                                          *                     *   *     **                                                  *                     *        *                                                           ** ***********   **      *   *   *     *   *  *                                                                        *  *                      *                                                                                                                        *             *         *           *                                                                                          * *                                                                              *                     * *  * *   *                             ****                                *     *         *     *        **                  *     *         *   *     * *     * *   *     *****                *   *  *    *  *    *    *                                 * * **  ***   *  **          *  *   *      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8665] PF08862            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1829:Domain of unknown fun  ----1---------------------------1-1-----1--1----1-----------1-1----- ----------------------------------------------------111----------------------2-------------1----------------1-----------------------11-------------1-------------------------------------------------------------------------------------331-11111333111--------11----1-------------------------111211111-1----1---------11---111------111-----------11111--------------------------------------1------------------------------------------1----------------------------------------1-----2----------------------------------------------------------------1-------1------1------------1-----------1--------------------------1---1------------------------------111-3-5-1----24-1--------------1---------------------------------------------------------------------------------------------------------------1------------------------1------------------------------------------------1-------1--------------------1--------------------------- -3--2-----------11-----------------1----------1-1----1----------1-----------1-----------1---1----------12----1--------1------1---2---1----------------------------1---------------1------1--1-131------
 ction DUF1829                      *                           * *     *  *    *           * *                                                          ***                      *             *                *                       **             *                                                                                     *** ***********        **    *                         ********* *    *         **   ***      ***           *****                                      *                                          *                                        *     *                                                                *       *      *            *           *                          *   *                              *** * * *    ** *              *                                                                                                               *                        *                                                *       *                    *                             *  *           **                 *          * *    *          *           *           *   *          **    *        *      *   *   *                            *               *      *  * ***      
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8666] PF07033            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         3                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
 Orthopox_B11R:Orthopoxvirus B  ------1-2---11-----1--------------------------1---11---------------- ----1-------------------------------------------1-----------------------------------------------------------------------------------------------------1---------------21--------1-1----------1---11---1-------------------------------1-----------------------------------------------1111-----------------1111111111111-------------------------1-11-----1---------------1--------1-1---------------------------------------------------------11------------------------------------------------1---1------------------------------------------------------------------1-----------------------------------------------1------1112-1-----------------------1----3--1-------------------------------------1--1-----------------------------------------------------------------------1-------1------1-----------------------------------------------------------------------------------1--11---------------------1---1-----------11--------------- 1-21-1-----------1--------1-------------------1---1-----------11-----11----------1111------------------1-----21-----2-----------------------1----------1---------1--1-21--2-2------------1-----------1-
 11R protein                          * *   **     *                          *   **                     *                                           *                                                                                                     *               **        * *          *   **   *                               *                                               ****                 *************                         * **     *               *        * *                                                         **                                                *   *                                                                  *                                               *      **** *                       *    *  *                                     *  *                                                                       *       *      *                                                                                   *  **                     *   *           **                * ** *           *        *                   *   *           **     **          ****                  *     **     *                       *          *         *  * **  * *            *           * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8667] PF01289            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Thiol_cytolysin:Thiol-activat  --------1111111---------1------------------------------------------- -----1----------------------------------------------------------------------------------2--3-2-----2-1-1----1----------------------------------------------------------1--------------1----------11111111-111111------112---1----1111-1-----------------1-------------------------1------1------222222212221111111111111-11---111------2121-11111----211--1-------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------11--1-------------------------------1----------11---------------------1---------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------1----------11------------------------------------------------------------------------------------- -----------21----1--------1-------1------11----1-------1--1-------------1------------------------------1-----1---1------------------------------------------1----11--1--1-----------------1--11---1----
 ed cytolysin                           *******         *                                                 *                                                                                  *  * *     * * *    *                                                          *              *          ******** ******      ***   *    **** *                 *                         *      *      ************************ **   ***      **** *****    ***  *                         *                                                                                                                                                                 **  *                               *          **                     *                     *                                                                                                                                                         *                                    *          **                                                                                                 **    *        *       *      **    *       *  *             *                              *     *   *                                          *    **  *  *                 *  **   *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8668] PF10768            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 FliX:Class II flagellar assem  ----------------1--------------------------------------------------- ---1---------------------1----------1------3----------------11-1-----11-------------------------------------------------------------------1------1-----------1------------------------------------------------------------------111111-----------------------1----------------------------------------------------------------------------------------111------------------------------1111-------11111122111------------11121212--1----1----------1-1------------------1----111-----------------------------------1----111-------------------------------------1----2---------------------------1--1------------------1----------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1111--------------------------1-------------------------------------1-- ------1-11------1-1----------1------1-----------------11--------------------------11-------21--21--1-11----11-11111111-----------------------1--2-1---------1----1-111----1-----1--1-111-121------21191
 bly regulator                                  *                                                       *                     *          *      *                ** *     **                                                                   *      *           *                                                                  ******                       *                                                                                        ***                              ****       ***********            ********  *    *          * *                  *    ***                                   *    ***                                     *    *                           *  *                  *                                                    *                                                                                                                                                                                            *  ****                          *                                     *         * **      * *          *      *                 **                          **       **  **  * **    ** ********                       *  * *         *    * ***    *     *  * *** ***      *****
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8669] PF05579            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                                                                     
 Peptidase_S32:Equine arteriti  -----------------1----------1-------------------1-2-1-------------3- ------------11------------------1----1----------------------------1-----------------------12------------1-----------------------------------------------------------1----1-------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------1----------1-----1--1----1-----------------------12------------------------1----------------------1----------------------------------------------------------------------------2-----------------------1-----1-----------------------1------------------------------------------------------------------------------1---------------------------------------1-------------------------------------------------------------------------------------------------1-----------------------------------------------1------------------------------------------------1------- --111-----1-11---------------2311-13--111--1------412---------------11------1-------------17--13--------1--12--11-1---2---2----320-4-41--11----1--21-1------1---1---1--------1-----6-----11-1111-------
 s virus serine endopeptidase                    *          *                   * * *             *              **                  *    *                            *                       **            *                                                           *    *                                                             *                                                                                                                                    *          *     *  *    *                       **                        *                      *                                                                            *                       *     *                       *                                                                              *                                       *                                                                                                 *                                               *                                                *          ***     * **               **** **  ***  *      ***               **      *             **  **        *  **  ** *   *   *    *** * **  **    *  ** *      *   *   *        *     *     ** ****       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8670] PF11165            142                                                                                                                                                                                                                         1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
 DUF2949:Protein of unknown fu  ------------------1------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------07745423222112111122432331111111111-1--------1------1------------------------------------------------------------------------------------------------------------------------------------------------------1---------1----------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------1------------------1--1-11---------------1--112-----1-1---------------------------1---1----------------------------------1--------1--------------------------------------------------------------------------------------------1----------------------------11111----1-----1-1---------------------------------------------------1--------------1--------------------1---------- -1---------2--------------1-----1-------------11------------------1--------------------------1-----------1-------2-----------------------------12-----211-----------------1-----------------1---------1
 nction (DUF2949)                                 *                                                                                                                                                                                                   *********************************** *        *      *                                                                                                                                                      *         *                                        *                                                                                                                                                   *                  *  * **               *  ***     * *                           *   *                                  *        *                                                                                            *                            *****    *     * *                                                   *              *                    *            *         *              *     *             **                  *                          *           *       *                             **     ***                 *                 *         *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8671] PF07071            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1341:Protein of unknown fu  ------------------1------------------------------------------------- -------------------------1------------1----------1----1-------------------------------11---------------------------------------------------------1----------------------1------------------------11111111-1111111----11111---1--111111111--1----------------2---12------1--11---------------------------------------------------------------------1--------------1------------------------------------------------------------------------------1--1----------------------------------------------------------------------------------------------------------------------------------------1-----------------1---11-1----1--------------------------11------------------------1----------------211--11--------1---------1-----------111-----2-122222222222221---------1----------------------------------------------------1-------1----------------------111-------1----------------------------------------------------------------------------- ----1---1--------1--------1-------1---------------1--1-----------------------------------------------1------21---1-11--1----1---12---1111------11----1----------12---11------------------1----1--------
 nction (DUF1341)                                 *                                                                           *            *          *    *                               **                                                         *                      *                        ******** *******    *****   *  *********  *                *   **      *  **                                                                     *              *                                                                              *  *                                                                                                                                        *                 *   ** *    *                          **                        *                ***  **        *         *           ***     * ***************         *                                                    *       *                      ***       *                                                                                  *   *        *        *       *               *  *                                               *      **   * **  *    *   **   ****      **    *          **   **                  *    *        
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8672] PF01893            142                                                                                                                                                                                                                                                                                                                                                                                                                                                              1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
 UPF0058:Uncharacterised prote  -----------------------2322223321-12222222222112--1211-------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1-1------------1------------------------1-------------------2---------------------0-------------1----------1--1---1--------1---------------1-----------------------------------------------------111-------------------------------------------------------------------------------------------------------------------------------11-1-11---------1--------------------------------------------------------------------------------------1----------------111--1-------------------------------------------1-----11------1--------------1--------------------------------------------------------------------------------1-------------------- -------------------4---1-1-----------1111----------1-----------------11--------------1---------1----1---1----1-----2--1-----21-1------23--1-3----1-------31----121-1--------1-------------11-----------
 in family UPF0058                                     ********** **************  ****                                                                                                                                                                                                                                                                                                               *   * *            *                        *                   *                     *             *          *  *   *        *               *                                                     ***                                                                                                                               ** * **         *                                                                                      *                ***  *                                           *     **      *              *                                                                                *                                        *   * *           ****          *                 **              *         *    *   *    *     *  *     ** *      **  * *    *       **    *** *        *             **           
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8673] PF12005            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             1                     
 DUF3499:Protein of unknown fu  ------------------------1------------------------------------------- ----111111111121111-11111111111111112111122121111111111111-111113112111----1---------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------1------------------------1-11--------1-------------------------1-------------------------1-------1-----------------1---------------------------------11-1----------1-------------1----1-----------------1--------------------------------------------------1---------------------------------1-------------------------------11-----------------------------------------------------------------------------------------------------------------1--------------------------1--------1----------------------------------------------------------------------------------------------1---- --------11--111-1-------------------------------------11---------------------------11----2111-1----------1----------------------------------1------------11---1------------------3--------11---11--1--2
 nction (DUF3499)                                       *                                                *************** ************************************** ************    *                                                               *                                                                                                                                                                                      *                        *                        * **        *                         *                         *       *                 *                                 ** *          *             *    *                 *                                                  *                                 *                               **                                                                                                                 *                          *        *                                                                                              *             **  *** *                                     **                           **    **** *          *                                  *            **   *                  *        **   **  *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8674] PF05465            142                            11                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
 Halo_GVPC:Halobacterial gas v  -------------------------93-6--------------------------------------- -1-------------21----2-----------11111-11---------------1------------1---------------------------------------------------------------------------------1-1-----------1------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------------------1----------2----------------------------------1-------------------1----11------------111----------------1----------------------------------------------11-----------------1-1-----------1--------------------------------1-------------------------------------------------1-1--------------------------------------------------------------------------------------2-------2-------------------1-----2--------------------------------------------1---------------------------------------------------------------- -----1--2------11---1--1-1--------------------1---1-----1--------1-------------------------11----------1---1--1--1--------1-----12-2-2----------1-111------1-1-------1-1--2-11--2-1-221-2-1141------11-
 esicle protein C (GVPC) repea                           ** *                                         *             **    *           ***** **               *            *                                                                                 * *           *                                                                                          **                                                                                                                                                             *          *                                  *                   *    **            ***                *                                              **                 * *           *                                *                                                 * *                                                                                      *       *                   *     *                                            *                                                                      *  *      **   *  * *                    *   *     *        *                         **          *   *  *  *        *     ** * *          * ***      * *       * *  * **  * * *** * ****      ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8675] PF11814            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3335:Domain of unknown fun  ------------------------------------------1------1------------------ ------1-----------1-1------------------1---1---1--------------------1---------1---1-1------------------------------------------------1--11----------1---------------------------------------------------------1----------11--------------------------------------------------1--------111----1--------------------------1------------------------------------------11-------------------------1-----1------------------1-------1--2------1-------------------------------------1---------------------------------------------------1---------------------------1-1---------------------1---1----1-----1--1-------1----11--------------------------------111-111-1-----1------------------1-------------------------------------------1-----------------------------------1-----------------------11-1---------------------------1111111--1-1-1111111-11-11-----22222---21----------------1---------------1----------------------------------------- --------2---11--1-1--------------1------------1----1----2------------1------------------1---1-1--------22----31-11---1------1--2-1---2----------------------1----1-4--1----1-------2-----1------1--1--1
 ction (DUF3335)                                                          *      *                         *           * *                  *   *   *                    *         *   * *                                                *  **          *                                                         *          **                                                  *        ***    *                          *                                          **                         *     *                  *       *  *      *                                     *                                                   *                           * *                     *   *    *     *  *       *    **                                *** *** *     *                  *                                           *                                   *                       ** *                           *******  * * ******* ** **     *****   **                *               *                                                  *   **  * *              *            *    *    *            *                  *   * *        **    ** **   *      *  * *   *                      *    * *  *    *       *     *      *  *  *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8676] PF12517            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF3720:Protein of unknown fu  -----------------------------------------------1-------------------- ----1--1----------------------------1-----1----1----------------1------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------1-------------------------1------------------------------------------11------11--1---112---11---------------------------------------------------------------------1----------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------- ----1-1-21-------311---2-21--221111111111111--1-2----1112--1-1--1--1--------1---1------------1--------11---141---2-132-1-1-12----1----24--11---1-2-1-------1-21------3122--1----2----1--1134---3-211-31
 nction (DUF3720)                                                              *                         *  *                            *     *    *                *                                                                  *                                                                                                                                                                                                                                                     *                                                          *                         *                                          **      **  *   ***   **                                                                     *                                  *                                                                                                                                                                    *                                                                                                                         * * **       ***   * **  ***************  * *    ****  * *  *  *        *   *            *        **   ***   * *** * * **    *    **  **   * * *       * **      ****  *    *    *  ****   * *** **
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8677] PF00283            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Cytochrom_B559:Cytochrome b55  ---------------------------------------------------------1---------- -1--1--------------------1-----------------------------------------------11-1----------1-------------------------------------11------------------3222222222223222222222222223233223233------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------11-----------------------------------------------------------------------11-----------1----------------------1---------------1----------------------------------------------------------------------------------------------------------------1--------2------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------1--1-1--------------------------------1--1---------------11-----------------1--1----1----------5------------------------------1----------------1--11---1---2--1-2-1------2-215--2-------
 9, alpha (gene psbE) and beta                                                           *            *  *                    *                                               ** *          *                                     **                  *************************************                                    *                                                                                                                                     **                                                                       **           *                      *               *                                                                                                                *        *                                                      *                                                                                                                                                                                                                                                                                    *  * *                                *  *               **                 *  *    *          *                              *                *  **   *   *  * * *      * ***  *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8678] PF10840            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2645:Protein of unknown fu  ------------------------------------------------------------1------- -----------------11-1---1-111111-------1-------------------------------------------------------------1---11------------------------------------1--12---1---------------------1----1--------1-1-1-------1-----1---------1--------------1--------------------------------------------1-------------------------------------------------1------------1------1--1------------1--------------------------------------------------------------------------------1-----------------1-----1---------------------------------------------1----------------------------------------------------1---------------------------------------------------------------------1--------1------------------------------1--11---11-1----11-2----1-1---1--1---341111-1-1-11-11-1--1-----------1-11------------------------1----------------------------------1--------------------11--1----------------------------1121-----1--------------------------------------1----- --1--1----------------------------------------------------------1------1-----11------1-----1---------1--1-------------2111222111-1----11-1-12-13-1--11-21------------111----2------------2--4----------
 nction (DUF2645)                                                                           *                         ** *   * ******       *                                                             *   **                                    *  **   *                     *    *        * * *       *     *         *              *                                            *                                                 *            *      *  *            *                                                                                *                 *     *                                             *                                                    *                                                                     *        *                              *  **   ** *    ** *    * *   *  *   ****** * * ** ** *  *           * **                        *                                  *                    **  *                            ****     *                                      *        *  *                                                          *      *     **      *     *         *  *             ********** *    ** * ** ** *  ** **            ***    *            *  *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8679] PF06366            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 FlhE:Flagellar protein FlhE    -------------------------------------------------------------------- --1---------------------------------------------------------------------------------------------1----------11-----------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1--------------------------------------------------------------------------------1-------------1--1-------2------1111-----------------------------------------------------------------------------------------------------1--------------------------------------11111111111111111-1111111111111111111-111212-11111111111111111111111---1111111-1111----------------11-------------------------1------1---------2--------------------------------------------------------------------------------------------------- --11--1---1------------1-----1------------------------1----1----------1--------------------1-21------1------1--------------------1-1----------11--------1-----------------1------11------111------3714-
                                                                                                       *                                                                                             *          **                                                                                                                       *                                                                                                                                                                                        * *                                                                                *             *  *       *      ****                                                                                                     *                                      ***************** ******************* ****** ***********************   ******* ****                **                         *      *         *                                                                                                      **  *   *            *     *                        *    *          *                    * **      *      *                    * *          **        *                 *      **      ***      **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8680] PF03242            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      1 1          
 LEA_3:Late embryogenesis abun  -------------------------------------------------------------------- ----1----------111------1------1----------------------------1--------------------------------------------------------------1----------------------------------1---1--1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-1-121--------------1----1--1-----1-12111--11---------------------1-----1----------------------------------------------------------------1-----------1---------------1-------------------1---1-------------------1-----------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------1-11----------1---111-1-2----111-1131122--12-2-11--112--------------1-1--------------1----------1---1----11---1-----1---1-------------1-11-1-------------213--------1---1----11--3131-83-2---1-
 dant protein                                                                                            *          ***      *      *                            *                                                              *                                  *   *  *                                                                                                                                                                                                                             *** * ***              *    *  *     * *****  **                     *     *                                                                *           *               *                   *   *                   *                                         *                                                                                                                                                                                                                                                                                          * **          *   *** * *    *** *******  ** * **  ***              * *              *          *   *    **   *     *   *             * ** *             ***        *   *    **  **** ** *   * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8681] PF09611            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     1                                             
 Cas_Csy1:CRISPR-associated pr  -------------------------------------------------------------------- ---------------11----------------111-----------------------------------------------------------------------1----1------------------------------------------------------2--1-------------------1-1---------------11------------------------------------------------------------------11-------------------------------------11------------------------------1-----------------------------------------------------------------------------------------------------------------------1----------------------------1-1-------------------1------------1--------1-1----1--1----11----------------------2------------1--------------------------------------1-------1--11-------1---------11-----------11-11-----1-1---------1----1----------1-21----------------------------11111111111----121112--------111-----------121--1-1--1---1----------------------------------1------------------------------------------------------------------------------ --11--1----1-----------------1-------1111----------111------1------1---------1-----------------2-----1-1--11-1-1----2----1-1---1-------2--------1--------04-----1-111-111-1-1--------1--11--1----------
 otein (Cas_Csy1)                                                                                                   **                ***                                                                       *    *                                                      *  *                   * *               **                                                                  **                                     **                              *                                                                                                                       *                            * *                   *            *        * *    *  *    **                      *            *                                      *       *  **       *         **           ** **     * *         *    *          * **                            ***********    ******        ***           ***  * *  *   *                                  *                                                                                 **  *    *                 *       ****          ***      *      *         *                 *     * *  ** * *    *    * *   *       *        *        **     * *** *** * *        *  **  *          
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8682] PF05938            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     1  3 4        
 Self-incomp_S1:Plant self-inc  -------------------------------------------------------------------- ------------------------------------1-11-----------------------------------------------------------------------------------1------------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1------------------1--------------------------------------------------------------------------------1--------------------------------1----1-------------------------------------------------------------------------------------------------------1------------------- -2------1--------------------------1--1--12------11-------------1------------------------------------1--------1-------------1--3---1-1---1----------1----2--------3--------131-----------2--0-74------1
 ompatibility protein S1                                                                                                                 * **                                                                                   *            **                                                                                                                                                                                                            **                                                                                                                                                                                                                                                                                       *                             *                  *                                                                                *                                *    *                                                                                                       *                     *      *                          *  *  **      **             *                                    *        *             *  *   * *   *          *    *        *        ***           *  * **      *
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8683] PF03671            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Ufm1:Ubiquitin fold modifier   -------------------------------------------------------------------- -----------------------------------------------------------1--1-------------------------------------------------------------------------------------------------------1----1----------------------------------------------------------------------------------------------------------------------------------11111111--------------------------------------------------------------------------------------1------------------------------1--1--------------------------------------------------------------------------1111------11-----------------2---------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- --1111--2111-----1------------------1-------------------1-----------------1----1-----1----1---1------2-1----1111-2111---11-12113-5-1-233111-1111111-1-11-5142222111212111111111--11----111123-11---111-
 1 protein                                                                                                                                                      *  *                                                                                                       *    *                                                                                                                                  ********                                                                                      *                              *  *                                                                          ****      **                 *                                             *                                                                                                                                                                                                                                                                                                                                           *     ****  ****     *                  *                   *                 *    *     *    *   *      * *    **** ****   ** ***** * * ****** ******* * ** **********************  **    ****** **   *** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8684] PF10949            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2777:Protein of unknown fu  -------------------------------------------------------------------- ----------------------------------------------------------------------------------------1------1----------------------------1----------------------11-11---------------2--1--------------------11111111111111131111121111111------------------1----------------------------------1-------------------------------1-------------------1----------------111-1----1----1----------------------------1----------------------------1--------------11--------------------------------------------2----------------------------------------------------------------------------11---------------------------------------------1-----1------------------------------------------------11------------------------------------------------------1-------------1-1-1-1--------------------------1---------1--------------------------------------------1------------------------------------------------------------------------------------------------------ ----11----------1----1-------------1-----------------1------------------------11------------1--------1--1-------11-11-1-1-----1314-21335-2111-131-111-3---12111-----------1-2------------2-----2--1----
 nction (DUF2777)                                                                                                                                                                            *      *                            *                      ** **               *  *                    *****************************                  *                                  *                               *                   *                *** *    *    *                            *                            *              **                                            *                                                                            **                                             *     *                                                **                                                      *             * * * *                          *         *                                            *                                                                                                           **          *    *             *                 *                        **            *        *  *       ** ** * *     **** ***** **** *** *** *   *****           * *            *     *  *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8685] PF10549            142                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 ORF11CD3:ORF11CD3 domain       -------------------------------------------------------------------- ----------------------------------------------------------------------------------------11-----------------------------------1-1--1----1---------------------------------1--------------------1---------------------------1-------------------------------------1------------------1--------------------------------------------------------1------------------------------1----------11-------------1-----------------------------------------------1-----51--2--------1------------------------------------------111------------------------------------------------------1------------------------11--------2----------------------1-----------------1--1-1-----------------1----------------1-------75--1-12116----13--162------1-----------1-1--------1-------1-----------------1-----------------------1---11-1---111------------------------------------------------------12------------1--------------------------------------------------- ------1---1-----111---------------------------1------1--------------------------------------1--2-----3-1----111---------------------------------1--1---1-----111-11-111---2-2---2--2--------1-11-1-----
                                                                                                                                                                                             **                                   * *  *    *                                 *                    *                           *                                     *                  *                                                        *                              *          **             *                                               *     **  *        *                                          ***                                                      *                        **        *                      *                 *  * *                 *                *       **  * *****    **  ***      *           * *        *       *                 *                       *   ** *   ***                                                      **            *                                                          *   *     ***                           *      *                                      *  *     * *    ***                                 *  *   *     *** ** ***   * *   *  *        * ** *     
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8686] PF07381            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1495:Winged helix DNA-bind  11---------1-----1--1111-----------11-11112-1---------1211111-11---- --------------------------1-------------------------------------------------------------1-1--------------------------------------1-----------------21------------------------1----------------------------------------------------------------------------------------------------1--------------------------------------------------1-1111111-1---11------------------1--------------------------1-------------------------------------------------------------------------------------------11---------------------------------------------------------1--1------------------------------------------------1----------2-----------------------------------------11------------------------------1----111111111--1111113121111111111--------111-1111111-1--1-121----------------------------------------------1----1-1-11------------------------------------------------------------------------------------------------------------------------1 ----1-----1-------------------1-1-----1-------11--1-----------11---------------------1---------1------------11------------------------------1----------------------21---------1---------1-131--1--1--1-
 ing domain (DUF1495)           **         *     *  ****           ** ***** *         ******* **                               *                                                             * *                                      *                 **                        *                                                                                                    *                                                  * ******* *   **                  *                          *                                                                                           **                                                         *  *                                                *          *                                         **                              *    *********  *******************        *** ******* *  * ***                                              *    * * **                                                                                                                        *     *     *                   * *     *       **  *           **                     *         *            **                              *                      **         *         * ***  *  *  * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8687] PF11783            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Cytochrome_cB:Cytochrome c ba  ---1-1-------------------------------------------11----------------- ----------------------------------------------------------------1---------------------------------------1-------------------1--11111211------------2------------------1------------------------1------------------------1--------------------------------------------------11----------------------------------------------------------------------------------------------2----------1-------------1----------------------1-------------------------------------------------1--11------------------------------------------------------------1---------1--------3-------------------------2111211-11111-1247222-12242---1-1---------1-1-1--11-----------1------1-111-11111-1111-2------1-------------------------------------------------------------------------------------------------------2---1---------------------1--------------------------------------------------------------1--------------------------------------------------------1 ---1--1----------1--1------------1------------12----1-------------1----1---------1-1-----1-----------1--------11-------------1------------1--------------------11--2----1----------1-----1--1------21--
 cterial                           * *                                           **                                                                                  *                                       *                   *  ********            *                  *                        *                        *                                                  **                                                                                              *          *             *                      *                                                 *  **                                                            *         *        *                         ******* ***** ******* *****   * *         * * *  **           *      * *** ***** **** *      *                                                                                                       *   *                     *                                                              *                                                        *    *  *          *  *            *            **    *             *    *         * *     *           *        **             *            *                    **  *    *          *     *  *      **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8688] PF07161            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1396:Protein of unknown fu  ---1----1------1--------111--1-------------------------------------- -1-12---------11144-41225144444511111-1----11-------1-------222--4-132------------------------------------1----------------------------11111--111-1----------1----------------------------------------------------------------1-------1----------------------------------11-------------------------------1---------------------------------------------------2----11----1-1---------------------------1------------------------------------------1-----1---------------------1----------------------------------------------------11-----------------------------------------------1-----1-------------------------------------------------------1---------------------1-----------------------1-1--------------------------------------------------------------------------------------------------111--------------------------------------------------------------1--------1------------------------------------------------------------------- -----------------------1-1--------------------1-------11--------1---1-------1----------------------------------------------------------1----1---------------------11--1------------------------------2-
 nction (DUF1396)                  *    *      *        ***  *                                        * **         ***** ***************** *    **       *       ***  * ***                                    *                            *****  *** *          *                                                                *       *                                  **                               *                                                   *    **    * *                           *                                          *     *                     *                                                    **                                               *     *                                                       *                     *                       * *                                                                                                  ***                                                              *        *                                                                                           * *                    *       **        *   *       *                                                          *    *                     **  *                              * 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8689] PF06069            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 PerC:PerC transcriptional act  ---1----------------------------------------------------------1----- 111--------------11-1----111111--111---1---1---------1------11---1-------------------------------------------1----------------------------1--------------------------1----------------1------------------------------------------11-1-----------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------1--------------------------1---------------------------------------------------------1-----1--------------------------------------------------11-------1-----------11----------------------------------------------1----------------------1--------------------2---1-15-212-4---1-1--22-12341--1--31221----1---111--------------11------------1-1------------1----------13-1--1-------------------------------------------------------1----------------------------------------------------------------------2-1- 1--------------1---1----1----1----------111----1---1------1--------------------------------1-------------------------1--------------------------------------1---1112-311--1-------1-----1---1--11-1----
 ivator                            *                                                          *      ***              ** *    ******  ***   *   *         *      **   *                                           *                            *                          *                *                                          ** *                                                                                                                                                           *                                 *                          *                                                         *     *                                                  **       *           **                                              *                      *                    *   * ** *** *   * *  ** *****  *  *****    *   ***              **            * *            *          ** *  *                                                       *                                                                      * *  *              *   *    *    *          ***    *   *      *                                *                         *                                      *   **** ***  *       *     *   *  ** *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8690] PF05628            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Borrelia_P13:Borrelia membran  -----1---------------------1--------------1---------1----------1---- ---------------------------------------1--------1-----1---1---------------------------1-111---------1-------2---------------------------11-------------1-------1----------------1---1--------2-1----------1-------------------1--------2----------------------------------------------111------------------------1111--------------1---1111111-2------1111---------------------1--12--1------------1-1-------------------------------------------------1-1-------------------1----------------11------------------------------1-------1------------1--------------------------------------2-----------------------11-2----------1-1-----------1------1----------1--------------1-1------------------------1-----------------------------1-1----------------------------------------------1----------1-----1----------1----------------------------------------------------------1-1-------3--11--864121111-----------------------------11---------- --------------1----------------------1--1--1---1----------------------1----------------------1-----1-1-1------1---------1-------------------------------------1-1--1--1-----2----------------------12--
 e protein P13                       *                     *              *         *          *                                            *        *     *   *                           * ***         *       *                           **             *       *                *   *        * *          *                   *        *                                              ***                        ****              *   ******* *      ****                     *  **  *            * *                                                 * *                   *                **                              *       *            *                                      *                       ** *          * *           *      *          *              * *                        *                             * *                                              *          *     *          *                                                          * *       *  **  *********                             **                         *                      *  *  *   *                      *                      *     * * *      *         *                                     * *  *  *     *                      **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8691] PF09941            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2173:Uncharacterized conse  ------31333333321--1------------------------1-----11--11------------ ----------------------11--------1---1-1-----------------1--------------------------2222-----------------------------------------------------------11-11--111--------11--1--------------------------------------------------------1---1----------------------------------------------------------1-1-111111-------------------------1-1------1--------------1--1--------------------2------------1--------------------------------1-1-----11-----------1--------1---------------------------------------------------------------------------------------1-----11--------6----------------1----------------------------------------------------------11-------------------1----------------3--------------------------------------------1---------1-------1-11--------------------------1-----------------------------------------------------------------------------1------1----------------------------------------------------------------------- ------------11--1---------1-------------1--11111-----111------------------------------------1---------------1-1-12------------1----------------1----1--------------1-1----------11--2--11-11-1---11----
 rved protein (DUF2173)               ***********  *                        *     **  **                                   **        *   * *                 *                          ****                                                           ** **  ***        **  *                                                        *   *                                                          * * ******                         * *      *              *  *                    *            *                                * *     **           *        *                                                                                       *     **        *                *                                                          **                   *                *                                            *         *       * **                          *                                                                             *      *                                                                                    **  *         *             *  *****     ***                                    *               * * **            *                *    *              * *          **  *  ** ** *   **    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8692] PF06746            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          2        
 DUF1216:Protein of unknown fu  ------1------------------------------------------------------------- -21----------------------------------1--------------1----1--------------------------1---1-------------1--------------------------1---------------------------------------1---------------------------------------1--11---------------------------------1--------------1--------------------1----1-----------------------------------------------1----------------------------------------------1----------1-----------------------------------1--------------1---------------------1-----------------------------------------------------------1----11---------------------------------------------------------1------1--1------------------------------1-------------------------------------------1-------------------------------------1-----------------------------------------------------------------------------------------------------------------1----------------------------1-------1-------1----------------------------------------- ----------1-11-----------------111-1-----------1-----------------1-----1--1-1----1-------------2--1--2-111--1-1-1--------1--4------------1-----11--1-11-13---21---1--11-1--1-6------1--1--126-51--3215-
 nction (DUF1216)                     *                                                               **                                  *              *    *                          *   *             *                          *                                       *                                       *  **                                 *              *                    *    *                                               *                                              *          *                                   *              *                     *                                                           *    **                                                         *      *  *                              *                                           *                                     *                                                                                                                 *                            *       *       *                                                    * **                 *** *           *                 *     *  * *    *             *  *  * ***  * * *        *  *            *     **  * ** **   **   *  ** *  * *      *  *  *** **  **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8693] PF09950            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2184:Uncharacterized prote  ---------11111------------------------------------------------------ -1-------------------------------------------------1---------------------------1---------------------------1-------------------------------------1-1-11--------------------1--------------------------------------------1-------1-----1---------------------1----------------------------------------------------------------------3--------------------------------------------------------------1------------------------1--4---1--------1-111--1-------------11111111----1----------------------------------1---2---1---2--2----12---------2--1----2-------1-----------------------------------------1----------------------------------1-----1------------1--------------------------------------2-----------------1-1----------------22-2---1--1--12-1-1---1111-6------------1-------------------------1--1-------1-11-------------1-1--------------------------------1-------2111----------1-----------------------------------1------------- -1-------------1-----------------------------------1---1-1-------1---------1----------1--------------3---1--1-1------1-------1----------1----------------1------1-1---11------------------12--1---211--
 in conserved in bacteria (DUF           *****                                                        *                                                 *                           *                           *                                     * * **                    *                                            *       *     *                     *                                                                      *                                                              *                        *  *   *        * ***  *             ********    *                                  *   *   *   *  *    **         *  *    *       *                                         *                                  *     *            *                                      *                 * *                ** *   *  *  ** * *   **** *            *                         *  *       * **             * *                                *       ****          *                                   *               *             *                                   *   * *       *         *          *              *   *  * *      *       *          *                *      * *   **                  **  *   ***  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8694] PF07268            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 EppA_BapA:Exported protein pr  ---------------1-----------------------22-----------1--------------- -------------------------------------------1--------------------------------------------11-1----------1--11-1------------------------1------------1---------------------------------1-----------11111111111112211-11-11111---1------11------------1------------1-------------------------------------------------------------------1--1-----1-1----------1---------12------1---1--11-1---------------------------------------------------------------------------------------------1---1--1-----------------1-------------------------------------------------------------------------------------------------------------1--------------------------------1---1----1-1---------------------------------------------------1---------------------------1-------11-1--1------------------------1------------------------------------------1------------------------------11------------------11----722-------------------------1---1---------1------- ----21----1-------------------1----------------------1---------1-------1---------1111----------------2--111--11------1--1--1--13-4-1-1------1------1-------1------1---------1-1-------------3-----13---
 ecursor (EppA/BapA)                           *                       **           *                                                           *                                            ** *          *  ** *                        *            *                                 *           ***************** ** *****   *      **            *            *                                                                   *  *     * *          *         **      *   *  ** *                                                                                             *   *  *                 *                                                                                                             *                                *   *    * *                                                   *                           *       ** *  *                        *                                          *                              **                  **    ***                         *   *         *            **    *                   *                      *         *       *         ****                *  ***  **      *  *  *  ** * * *      *      *       *      *         * *             *     **   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8695] PF00997            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 Casein_kappa:Kappa casein      ---------------1----------------------------------1-1--------------- -------------------------------------------1-------1---------------1-------------------------------------------------------1------------------------------------------1-----------------------------11-1----------------------------------------------1-------------------------1------------------------------------------111--------------------1--------------------------1-1------1--------------------------------1------------------------------------------------------------------------------------------------------1-----------------------------------------1--------------------------------1--------------1-1---------------------------------------------------------------------1---------1-1---------1---------------1----1----------------------------------------------------------------------------------------------------1------------------------------------------------111-1------------12--------------------1---------- -1------1----------1-------11-------111-121--------11----11-1----------1---1-----------1-1----1--------1-1----1-2-1111221121411211-1-113211131121121112111---1----2421--21-1----1--------1--1------11--
                                               *                                  * *                                                           *       *               *                                                       *                                          *                             ** *                                              *                         *                                          ***                    *                          * *      *                                *                                                                                                      *                                         *                                *              * *                                                                     *         * *         *               *    *                                                                                                    *                                                *** *            **                    *            *      *          *       **       *** ***        **    ** *          *   *           * *    *        * *    * * **************** * *********************   *    ****  ** *    *        *  *      **  
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8696] PF09544            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
 DUF2381:Protein of unknown fu  ----------------1------------1-----------------------------1-------- ------------1-1--11-1---1------1------1-1-----1-----2-111-----------1-------------1-------------------------------------------------------1------1-------1------1--2-------1-----1----1------------------1----------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-1---1-------11-11-12-----------1----------------------------------1-------------------------------1--------2-----1----11-1-----------------------------------1------------1---------------------------12-01------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------31-----------------------------------11111111--------------------------------------------------------------2- ------1-1-11---1--1-1----12--11------------111--1-------------11--1--1---1----11-------------2-1---------1-1--3--1--1-------1--------------11---------------1---1-1--22-------1-1--6-1--------1---1212-
 nction (DUF2381)                               *            *                             *                     * *  ** *   *      *      * *     *     * ***           *             *                                                       *      *       *      *  *       *     *    *                  *                *                                                                                                                                                            *                   * *   *       ** ** **           *                                  *                               *        *     *    ** *                                   *            *                           ** **                                                                              *                                                                                                                               **                                   ********                                                              *        * * **   *  * *    **  **            ***  *             **  *  *   *    **             * *         * *  *  *  *       *              **               *   * *  **       * *  * *        *   **** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8697] PF04787            141                                                                                                                                                                                                                                                                                                                                        1                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
 Pox_H7:Late protein H7         -----------------1------------------------1------------------------1 --------11-----------------------------------------------------------------------------1--------------------------------------------------------------------------------1-----1-----------------1----------------------------------------111111-1111111----1----9--1-------41-------------------------------------------------------1-------------3--------1-1---------------1----------------------------------------------------11---------------------------1--------------------------------------------------------------------------------------------------1------------------------------------------------------------1111--------------------------1--------1---------------------------1--------------------------------------------------------------------------------------------------------------1---------------------------------------------------1------------------------------1--1-----------------------------1---1-1------- -1--11----------------------------------------------------------3-1-------1---------1-------------------------1----1------1-4113-6-1-213----3-11--1-11-1-5----1--23--21---111------3---------------5---
                                                 *                        *                        *         **                                                                             *                                                                                *     *                 *                                        ****** *******    *    *  *       **                                                       *             *        * *               *                                                    **                           *                                                                                                  *                                                            ****                          *        *                           *                                                                                                              *                                                   *                              *  *                             *   * *         *  **                                                          * *       *         *                         *    *      * **** * * ***    * **  * ** * *    *  **  **   ***      *               *   
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8698] PF10993            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2818:Protein of unknown fu  ------------------1------------1--------------------------------1--- ----------------------------------1-11-------------------------------------------------------------------1--------------------------------1------1-------------------------------------------1------------------------------1----------1----1--1---------------------------------------------1---------------------------------------1----11-1-------------1--1------------------2----------1---------------------------------3-------11---------------------------------------------------------------------------111111111111222211112221111111111--111-1111111-1111-11111111-1111-------------------1--1--------------------------1-------------11----------------------------------1-1-------1-------------------------------------------------------------------------------------------------1------------------------------------------------------1------------------1----------------------------------1---------------------------------- -----------------1------1-1-----------1-------------1-----------1------1-------------1--1---------------1------------2-1--1-21-1-2-2-111-------1-----11--1-----1------------1---------1--------1--1----
 nction (DUF2818)                                 *            *                                *                                      * **                                                                   *                                *      *                                           *                              *          *    *  *                                             *                                       *    ** *             *  *                  *          *                                 *       **                                                                           *********************************  *** ******* **** ******** ****                   *  *                          *             **                                  * *       *                                                                                                 *                                                      *                  *                                  *                                                    *      * *           *             *           *      *             *  *               *            * *  * ** * * * ***       *     **  *     *            *         *        *  *    
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8699] PF07105            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF1367:Protein of unknown fu  -----------------------1-------------1-----------------1------------ -------------------------------------------------------------------------------------------1--------------1----------------------------------------------------------------1--------------------------------------------1--------------1-----------------------------------1---------------------------------------------------------1-11111-1--------------1----------1-----111--------------------------------------------------1------------1--1----------------------------------------------------------------2---2----------------------21------1-----------2--------------1----1-------------1--1--------1------1------------------------------1--11--------1---1-----1-------1----------1---1---11----11-----2---------------11--141-3-1-21231-2221-2--112221------1----1--------------------2--11--2----22-----1----------1-1------------------------------------------------------------------------------------------------------------- 11-1-------1-----------------1----1--------111------------------11--------------1---------11---------------------1--1------------1-----1-1-----------1-------------1----3-------1-------1-----21----11-
 nction (DUF1367)                                      *             *                 *                                                                                                        *              *                                                                *                                            *              *                                   *                                                         * ***** *              *          *     ***                                                  *            *  *                                                                *   *                      **      *           *              *    *             *  *        *      *                              *  **        *   *     *       *          *   *   **    **     *               **  *** * * ***** **** *  ******      *    *                    *  **  *    **     *          * *                                                                                                              ** *       *                 *    *        ***                  **              *         **                     *  *            *     * *           *             *    *       *       *     **    ** 
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[8700] PF09876            141                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
 DUF2103:Predicted metal-bindi  -----------------------111111111-----------------11111-1-1111---1--- --3---------------------------------------------------------------------------------1111---------------------------------------------------------111-11111--1111112-1-1111111111111111-1------------------------------------1------------11111111111111-11------------------1--------------------------------------1-------111-------------------------------11----------11-----------------------------------------------------------11-------1------------------------------------------------------------1-------------------------------------1-------1----------------------------------------------------------------------------------------------------------------------------------------1--1-----------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------1------11111111------------------------------------------ ----111---1------------1-----------------------1----------------------1--1----------------11--1-------1----1-1-1-----------------------------------------------------4--1------11-1311-21211---1-------
 ng protein (DUF2103)                                  *********                 ***** * ****   *      *                                                                                 ****                                                         *** *****  ******* * **************** *                                    *            ************** **                  *                                      *       ***                               **          **                                                           **       *                                                            *                                     *       *                                                                                                                                        *  *                                   *                                                                                                                                               *      ********                                               ***   *            *                       *                      *  *                **  *       *    * * *                                                     *  *      ** **** *****   *       
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
                                aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
                                ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
                                eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
                                rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
                                01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================