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Summary of HM:SCP:REP&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbspGo To Summary with VIRUS
see 1-100     see 101-200   see 201-300   see 301-400   see 401-500   
see 501-600   see 601-700   see 701-800   see 801-900   see 901-1000  
see 1001-1100 see 1101-1200 see 1201-1300 see 1301-1400 see 1401-1500 
see 1501-1600 see 1601-1700 see 1701-1800 see 1801-1900 see 1901-2000 
see 2001-2100 see 2101-2200 see 2201-2300 see 2301-2400 see 2401-2500 
see 2501-2600 see 2601-2700 see 2701-2800 see 2801-2900 see 2901-3000 
see 3001-3100 see 3101-3200 see 3201-3300 see 3301-3379 

       aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
       ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
       eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
       rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
       01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[   1] --------1212222--11-111-2----------1---------------------1-11-----1- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------1----------------------------------------3-----------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------- DC9BNJy-U779******t******s*****x*y**t*q*w**trv********z*******ohujjdNqxprjmlsQqsaorqruRXS*******gbciY*u***F*vD*****************************************************************H96N*C8BAC******r89****6 * g.37.1.1 Classic zinc finger, C2H2
[   2] bbYHcWXXghhddbnkyRiejkqh*beu*pynSMNMRKROSPOmujn*Wl***EZnYYkWbOONh5HH px*c***********w*op-o*QQ**onnonm********p**********v***oz*SS*******************l***JHMJJ**vyFtacU24Zykkf*p*pxJKKKKKKLLLJJLJbijmjticpxqm*****UTW*w*******y*vvpfghmf**v*****ZnZdaaZmXdXY*xzno*uKvy*******************************************************************m*****pn***rk****************************yyxz******xy*****************************x***********sU****svxpdv*x**f***b*xssiWabWb*z****p*****************1**********uP**************dgf**********wtwwwwww***pp***CCDCCCCCAAGILJQRHPOLLJMNJDBFCPUejWX*********************************Kc*****************gsXh*vUZWUXWWqij******g*t**t**zx*Tvxtvx**v*******q*kWYdPYYZZYTQNRTPSPOUZhQTbll***x*q*eyl*ov**yot*xwtyty*****81Wl*qm742777****z************-***************************************************q8************65TXPVOOReijgqc***zzx*ywXjneepmu*ijnmnZnXjh*******************TPSNRTTRPc**************yx*uuvtprqZXWXEDtpssbccdKKJLJKLK*RpGFGDP-PPPNVQLdcZNScMYRIIIt**lkx*v*wO*ga VXXa***4**gj*****************y*************y*x*****************mufnjEsrgxsww*G*ytsnn**bkh************r****O*************************8*******************v**********************t*********************** * c.37.1.12 ABC transporter ATPase domain-like
[   3] ---1114533334437-121111-111D-5-1-----------61117-------1-6--12--1--- 5U*4q6444445447BBCC-CE55PECCCCCDDGGHMCiU5xZ*7895665687A5464498A4TINYbaQ6666566323D8111----2--1--7---1---51111333333333333334--1-----2--FDDPR---d3zKTUGDL9A55-1111189DGvnuj-1-----2----86844112143444343444554335333323344224321124223254122121-1112221112211112411511112211111-11111211212113111311221211121111111111111111332111123434111221233122334112215221252112222124211111--3U-w2---------4311--144321------------22221412-2---11321-231--31-6--313231--12222222211-1-712------------------------------11---12215533334122221143222214323624211132A963348537233A33532-----------5C71D6A3241-22111----2----2JKMK**-7-------------1----11---2111125328715231322244533343655257------3------12--3-12343233453-4322323333433332333-13-----212222222224242213233233--122222112121---412322775612J14-------1111-1--11111121325556673335421224522---------14345-----34432-14-5-1222----116-112333---------------1-1111111---212111111-1---1-1---68- *******6************************************************************q*************************************U*************************z****************************************************************** * d.144.1.7 Protein kinases, catalytic subunit
[   4] AA9AF9C9C999EAEFCC76999DILNEPKYIJIFDG68AB9FBHFHM3QOKYADEIDAC8A9EF5QB UMVJhXblllZfScbSXcc-cpNNcgbcabcTmpjwmqmkMurubfcbVXZXnjeVWXHHib*dkagrjpfRIMMVONKKdYGDGPINqorwJcXaQ22TcWTQmnfUhOKKKKKKKLKLLLLTRTWcqbWSvKSRUUQdLHNfLwfdlVYRMMOOTPSRSQfdJbmrvmJPNJNNLOLKKNaWNJJGHIZhccgcfidpddfhhdgfXZdcXaddckbbbWaYbXZWYbikQTSSUTSOSSSSTRTPQXUPaUTXWXUXXSTTQaXUVTYWUTMQQQTTUOOUUQPQUVSaUTSWRRSQRWWTQPQTWRRQQcZSSRaXaRVlbfpsrslpqocufhjccfYdZZgfPTcYkcVbYedYcTWPPTPOYEVQcSqZNPRLXOKnWXigmsTWZiaWkPPOQPPPPOPS-jlgg*phcdZaLaZZeXhYmoSXbOzRUSaRbOSaZUQSigiiiiiigWYiQUWTCCDBBAA9878zEEGKFGMGEGFFFEAGCCUaUYQYVSUmdadfbbiVVVVdaiibYeZQec*iaWhcKQiZUgbpqZkyilivbWwbYRZYVSVPPPQSZaNxcfbc*mbReeMcaVSRHdXmgbZvbtbagX*yhZUQMLKLKPNNPPPUSRQQOOcOIQUkejowk*cxalmyg**y*ovq*orqluti*muB1SjaTdADBEEEcdfjnbicoqhdfegra-mgZdmifdejmffZbcbbeieffieefdeabdadbhabffbaaeecdfYagW9accdffdaegfh89SRJLLJLcZXVcdnbgdabYUWQWVRNeRcXbZYXaVWWdWjhgkpgingpimghesrekUPRQOUPQPTsou*hkjskpwovyeedjjmfZaahgdhHIqUccVVZbJRLJHHHHVJTC9NDD-F89BEE88BBHDFDJCCCCRQQRMIHMIGHdSS *******D***s********************************************************g********t****************************W*************************i****************************************************************** * c.37.1.19 Tandem AAA-ATPase domain
[   5] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 52IL***-6--b-27----2111111-1111111--11111111111111-----1-1----1----------1---------1------------111------1-j4******************************************************************-KA7*735467sdM-H3CG59688 * g.3.11.1 EGF-type module
[   6] LKKGJIUWYZWZXUdeKRaQWNRHlbccZYeONINNeFFJJKFJPLOtMJ*caGlYckdNTGEGPAEF Yk*J*MFTQQKFJEVeblk1jwLLlnnmmnlWwmrqpp**K*t*bXMGLMKMbUbJLNBB*kbL*d****YLIHHYVMEGNZSPMdPPgikjDhQPV34MhSSTxVkUTDEEEEEEEDDEEEEOROZm*XPazfW*****FGG*T****pq*WTRRPOOPNNYfRs****MQMLMMLOMLLMZUVRRHJEaTQaabaaYhdVbaXYddZZXXSVYabadZTSPPQJKKNM*TJJHKMJIHKKKKJMJKIGNHQLIKJQIILHPQOONMMKQLHNFIHQHHLIFJIJIJIGGJGJIIKHHHJNLLIIMMIIJJKLJGFGIJJGY*rZyghejhjhVnVRmZYcRNRRZjOMwXrbR**rvspPcccigWYHKOkg*fRRcLLLLPfi*v*rXUfqgcrMPNPNOOOPPY1kzxeohomfpWHeXXhjc*pkbjcdjRSSidnmykjeTfTTTTTTTTqebMRnhgHHHHHHHHEECCHFRUGKWKGEKKFICJOBYYucPRZTOi****z**flll****srstbn***w***GKrwkz*eqXp**uwlZg*heXaaYKLKKJKJWWT*wtZ***mr**Y*u***P***************w*NOKMMMNNLMOINIIGIHHHSPLQTnqmtfg*mtbgefg*mlkoriupmplilposwA1Ljofq999AAAZXUaYSTceekcirpqh-dcadggfcdgcjdaabbbefbdZYgiUaZXabdYdcbbbgZZdaXURbWX*O8U***k****enc88HRUYSPYSTRRkY*ZrNIJMMMHKIIIKIJGVTWWVSSQSP*e****u****z*z****tFFFEFGEEFXdhmofjeiiqtonnYWdWfYWYZbMKLLDFkRYYVWXXHHHIIIGIUJEPIYHB-CAEBJAA888BGRA77DDFOoOaYTSRSTRZJM **do***D************************************************************e********U****************************i*************************f****************************************************************** * c.37.1.20 Extended AAA-ATPase domain
[   7] ---------------1-----------------1------------1-5-1----------------- -2-------------------------------------------------1-----1--1-1------2-------------------1----------61329x3-2-----------------------1----------1----------------------11--------------11------------------------------------------------------------------------------------------------2-------1--1-111-1-------11----------------1-------------1-------------1-9-213---------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------11-------------------------------111-1-----------------1--2C12-------------------------------------1-1-1-22221-1111-----------------------------45----1---2---113---4---------------------1-----------11----------------------------------4----------------------------------------------------------------------------------------------------------------------------------------1----w-1 ------2----------------1-1--------------------------1-----------------1---------------------------------1----1*****************************************************************-1----------1------111-- * b.1.1.4 I set domains
[   8] ----1--222222222-------1-----I6------------122---83-----111--1----6* 65A-W------1------------1-----------1---46295D4-9332898-1---8D217-1CFB43222322--21--11--7AA21522----D866MEDB8--------------1--1------9-599561-1C3-----------------------1-------------221--24-1616666645785A56B559671165D25172115554669p--------------------12-1--1-121----11------111-------1------------------------------------B21231111111-12W154-CB32-R--42I8-AB5-322112221A---12-111-----------------------------1------G------1--4------1-111-1--1-1--2----------------1-----------------------------------------2----1-111111--242223-----------3N-1-171--2-----1-----------------EP262----------DhFFM9x236798K2774--2333333433333333334242-----25I-1237-44516114-3616-353C---1-11-------311-1--983-315-1-A1-4134244944111111111122-3-----3-31--25--2122-2122--455345555445-------------1-F--1-11-----------2212--11---H2231-2-2--112-445111111-11----122222---221142125111-------18833451111111112--------------------------88123171---G2F ---121f-*WW-66D3542738454212222227873232222222222324225624243333211221222212221222222211122251111-11111111-*s3*****************************************************************-BE39335gAG36436A1RQ*c*q * b.1.2.1 Fibronectin type III
[   9] 655334EILJLHKJKE5I797784eKMRQQQO7B733A16333AC6CF7AGCD18864699CJG919H kq*K*IDURRZHJE*****-**XX****************N*s***eWEwrI*y*UH*44***C*q****Z9888A8A56IFzADHGCgddY5eED4--M*Ole*d*bs22222223332222GWURVdeTUfXWnnnwy675*N*rp*kkpIIMMWURWSVOaPv***hSPPRQSRUWRMTeWRKLFF8SH*cbibiqijajriqsigZlllvhkvHROneofJIIKKH**LMMMMMLKMLMMMMKXJJWRK9N6OUDHB6AdkEELKMMIGLKNPODDDCCBCDFFCCC9CACCB9B79B99A9A99989GDBBB6BBBH9B7UTGGGDGFHGFHxALL8GIBN8G43LE9B9JHLFDG797746888HCkHy*pr*55555*h***TQS*****ZdfgZbfcfey-***********8**************lzbu**zqy*jgnWWWWWWWW**zaWqpe66566666552356786795557456576Sl**uKd**n********************g********FPz**mZjbZ*r*u**RdbRQOQeNABECBCALMVmkUU*bjOCPPKNKMLNFeddXXLkMTtvsy**ISDFGC8EDDBH99FAAAAAAAH9GAKQRigPWgadQlSZSZUUZQbYVSTPZXXZRbb2-6MMNO222222bdpoPiRWccgWdbbaW-caXabaaYbXccbVVWZXXu*uoabURWPVVWWXVWWRWVWVPuXXSXWUWJ3ZXZZbcaXbZcZ339EJMIJKaaacMZ*jiA99JBM88978BBDElihmlNfKTQuY********uut**k***SFIFDFGEFHRROlLLNNMVYUTXknqotnkWYZNHHH74SHjjXWfe1111111191A----3-1-3-2-1---2631-----97ABAAB9C8HvJT 89FI***-*cQ7Yj************************************************tixQUXIiPY*b*aUOSRclllvsRcZ************l****3*************************-******t****xn*x*p*yo**********************x*********************** * c.2.1.2 Tyrosine-dependent oxidoreductases
[  10] BBBABCCACDDDBCBBHAJGIHHECEEEDFEED9FGHDEEEGGCBBCFBGLLHKCCCEGEE788F899 KKLDhMHJLKJIJFIIJKK-JNDDJOJJJJJHLNONTSRQGMKRMKFIMFGFMPQJHJAAPOLISRUdXXQJKLLIHHHHMOEKGKIIMMPIFIJKM67JJGLHKGKHGABBBBBB9BABBBBHIKHLKKIJHVKONNSTDDEPEhWUWTTXNNMLHHJIHHPROHYbZeFHIGFFFHIHIFKKJHHLIDNLMTSVUWVWYRZXYWXWRNLMLLYWYNMOVWPTQPONNPWbNOMNNNMMMMMMNMLNMMNJMLLJLLKIIIJNPKKOOLLFHMJLMLPPPMMMLOPMNMMPOPNPPOPLLLLLLLLLQMKKQNNONNOLMJMZWXbUWUbXbaVZVQdXWOPRQZVQKRNTQROXXSYRLQOJLMLPMHKOHINJHHJHFEFFJLMOOHILMLLNMIJJIJJIJKHK4MNKOMJJJLPGDPNNNONQOPPNOMHHJIIMNPPRQLJPHHHHHHHHGGGGGKLMEFDDEEEEAACCCCEFDBDECCCCCEEED9GGHIHOSRMQPOPQPNSLKLLNMPPNMMNIPOUQROSOEJNNONNNLMUPOPVRLOVKMPNOKJLMMLLKKNJQPRNTWPSKNMKTSMMKGTRXTSRVSTWTUYUbMWIIEGHHHIHGHJHJKJJFFKGIGGLLLQNQKQOKKOMRNMOMNLNSRNOOOOMPLPLC4KLPLIDCBDDDQMJOJMKPRTVQTWTTR-POQRTQRPSURUQONPNNPRSRKKKMMOMONMMNPNMNNONNNLMMMPPPPI9MOOPRPQNPRSRABFIGGGGHJIIKPNRMTMIKMINIFGFEIGGKLMKMKKPKNKPNPPVPPQTMLSWRPRWQUKKJIILKIKNQRRXPNPPNOSUQOKNJIKIJKKNHHHHHGLHJJJMLLDDDCDDCDMAJDDCDG-CCGDDFFFFFCIFFCCEEDIONHJKQLLKEIIG **Zj***9***p********************************************************v*************************************c*************************N****************************************************************** * c.37.1.8 G proteins
[  11] ----3-5778967779-1-1111321112122I2A5AC9BCBCdGMA*DF*pi-755C9962AA--8D j**2*21322212184477-7A44DC776778KFEGC5cS5eYoBG253531AEE533--NID1sLhut*O35554445236CQKWSV***l9xhkT11Q*Wcx**uWuDCCCDCCABAEEEEwPFcYdGMSt*X*****111*8*u*w***WeQPEFBAFJaWRy****6U7M8BAr5L9BcPNMNC8SBCJUQWOXVXbLUXaWVXRLLKNOTWYAEEKE77DCCBDAcQ6555555555555555555634439A45224555567447333334111342242122222211222434444443443431122322219J8dLPOPKOQPPQJCIFFNDCEEKT42I8F88HDEKB7CA8936H95JPwY*USTV88678WR*r*JLIRKRMW9999999899A-IJfHJxILHyO5VFDXfZlqqmcXUOWVfXPIDHHJPNKEEEEEEEEOIHBFsQi4444433323FP74IM57K65477365679IVcQIHOKJIZQQQSVQKKLGMLflUUUPJRjXhNWWSCOKIQePKK9UFLaMFHSkbOWYTD9A99AA9MHYMOZ****YWjmR**hfiR***ykfwcc******Zi9C885AA9ADC69789A889DFDJDMLVSGqoxxP*WXVRSTPabcQRTPUUbbQbt--HbRTb11-111HFDJEKELMMNLIJKKE-KKNLNIHIQJMIJHHLJHJLHIKJCCFJMIHJIJIKLMJJJJIHEAEEBBE91KGGGGGEGGFFG118W797879DDBMK*GQJKGDHD9AABAA87FIHIHHDECDAOkIGJHOQXUMOSORMPLJ745555454HLhhYKLLLLcdWccWRYQURTSTSHGIH35********TRSVVVTW*Y1-------------------------HEMDBBGCDCQ*XV rkbj***2***o******************************************v**********x**X**y*****l******z**************x******G*************************x****************************************************************** * a.118.8.1 Tetratricopeptide repeat (TPR)
[  12] JJBAEEBAGKKJIGICNRKMMJHJRJKOLKWG97788FMIMKFFMDELAAbNK6CECGA7DIGBA-77 GIUF*RNVaadFKFmWVNM-NhFFU*NNNNMMomons***G*U****MWlcM***ML*44jaeN*d****aTPPPhbXGFdZb9AA89BBC94D342--2G756H9ACEAAAAAAACCCCCCC8C97AD9BVBG9jpppp777obmdilaafTWRSIEFIJFPdJjydtQ9G87878I97A7tfVTTYa3ZJjuw*w*w**duy*xv**tqlip*v*NOauocTbabaYZ**IPPQPQPPQRPPPQRTNOMUhZTTbhVMNJNjkJJjeILJLUORSXVWVXQPQMSSTXWXYXXTVTVMMNNLOOOOONMNSQPUSOMMMTVoZi*bdabdhbRZTajdcKRRO*MQPFoQfFG**WaLNYaHGRONZBNSGBHrMNT9DA8E*w***WT***x*v*******y***1**********a9**************TMJ**********gdggggggqxxUfnd*55444444443344443454333333343EDb*RI*********************************Li**************q*wLcUd*nHJHHHHHFGId*u*l*MgdnxTj*ljxAeXTnLVVWPhgVml*FdKJIHHLLLNHFCCAA9BAAAHWKBHQP***u*z*T*l******u*************7-IIVGh211222****v************-************************ow*************************a2************44BL58558QSRSMT***dddnWpGNQNMWOQa*****h*Rfe*z*****************EDFA9EGADS****************sruroUWUFAAA43joFFBACCCBC9C989J8I88F75-1151444111341A22333NbYPOXyVYVHYB4 11--116-1---3FB56A6567676754455556645545554555759A6799666746443344342322444567BB44444433335365392433444655-JRb*hmcndVLHLHKIIkeLcK**S2fOtGNKIUJKOECJIJISHFXIcLM*BBAS*u*b*b**EIyG5da7t5B6FCcHI*6Q579Y88GG * c.94.1.1 Phosphate binding protein-like
[  13] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------- 11--FA1-1---47L453245533323232222333121322222244556789356563331131111111-11-1-11111111---11352364221121----913**********************4******************************************---14-----211141131-7892 * f.13.1.2 Rhodopsin-like
[  14] 32223-UMPQXRRSUR7P56856A7AA5B6DA31121-53321CH86A3-86312545843SRU3--- JLeD*JFflloHKOZOQKK-KZ11e*JKKJKOYcdfy***HoQroaYQGYWC*s*WEe33deWMrU****IFCGGONI36U6Q25222LMME3F332--BM6F7aBS7b222222222122225453442422-4EJJGB221GG836733534773315854436639312-11-14-1--JGFA911CT5hVVXVWWUbHYaWSacI7hdUkWWV8GFMDC8DDDDD8hrDJFFIFHHGHFFIGGQGENSBCN5JN5J848UVIJRUJAGFHNFDA98952234582222232123245444444454451222222119341GOAAACBBB5B66DKK49966112-7--22eR8AA1594G53132--649pKKb3884FXH*otLARXaQVKHKKPHJNILLe-XX*VV*a*IlF1wXXcWaWsqhcdraHJA8JXEEDGBFIUPUUUUUUTeaPIJCM3333333322336B9B79C75867662A44CXwNGReSTw*******************j********2AwsnGKbOPwHVNwVRaI5D4DgF8C89889252DJGCCF592749C65574BA9IB9B96KIFMOQ4B6462277B96333232233334342FFSJLHKEJAQFDMQNNQHJQUPPJHEMMKSO1117A7821-112xgmdSzbtxxyvtwvuw-vwqvxrvtswuvxywswwh***iqRWW*mut*v*yyzvq*qtx*abcokjhB2kYYXZaWUUYZY--49RTMTQSSTS69GSWB98ACB67867545AmnlnnJbAFFuG**v*p***Ry***NpmohRYVNeRPR3GMLTIIIJIMLLKMijYcWbaPON85552142883354---1-111--1------1-22-21111343432---35433332325HB6 67DCTSQ-*fO8KJc**************************************************Y**g*Zc*j*xwV**y*****lu*************w****3T*c**********************4******y*****s***s**f**********************BeaX*VRRk********oa****s * f.38.1.1 Glycerol-3-phosphate transporter
[  15] ---11-------------1--------1----------------------45------------1-4- -14-4----------------1--2------------2---M7M--------------------7-13871--------------1-13111----1-------154-1--------------3211131113A37553C---4-*PYEEFJ11--1-----2A4KhdrQ1-1111111111-1--11------------------------2-------------------------------------------------------------------------------------------------------------1-1--1111111-1-1---------1----1-----11-----1--1-1---E-----11-1--11---------------------2121111-12-------11-1-1------1------111111111111-1-1--2----------------------------------------------21111---11111-1------------2------------9------------------2---1------1-------12--1122224L-113432222211-3111111145323--1111-14212-11111231331211--121---1-1-------------------------------------------------11------------------------------------1-----2-----------1----------------------------2----131-2111-1------------1111122222-11------------------2-------21112111-1--------------------------4122121422-2-- *******E**************************************************************************************************v******************************************************************************************** * b.69.4.1 WD40-repeat
[  16] ----------------------------1--------------------1------------------ ------1--------------------------------------1--------------------------------------------------------G-3--12-----------------2------------------------1-----------A----23-----4------------------------------1-----------------------1--------------------------------------------------------------------------------------------1--------------------------------------------------e3----------4---------------------------------------1-444-----1B1----222---------------29--------------------------------------------------------------------------1--------4---------------------3--H--1---1-------4---5-----------2-------------------------------2E--2-1----AL1---51211E-1------------------------------------------------------1--------------------------------------------------------2-D------------------------1-----------------------------B8A--4734-2-------------------F------------------------------------------------------2-- ------*----------------------------------------------------------------------------------------------------C-1*****************************************************************--------------------G--- * b.1.6.1 Cadherin
[  17] ----------------------------------------------14-------------------- -14-------------------------------------------------------------------------------------44341422----22--311-3--------------122122222222222-------C666443443344433333348854333332233332-----22-----------------------------------------------------------------------------------------------------------------------------------------------------------------5--11-1111-1-11-------1-1---------------------------------------------------------------------------------------------------------------------------------1------------------------1-------11333342122--2-------------------3----232343333-111111211-----7-21111-------111111111--11---2212-12-2221111111111111111111--121----------------------------------------------------------------------------------------------122222-1112-2-1---------------1111111--------------------------------22221111122211------------------443333---------1------------------------------------2111 **r****7***P********************************************************c********g****************************U*************************j******************************************d*********************** * d.58.7.1 Canonical RBD
[  18] -----------------------Bf98I4S9L--C3-133333*m1C*5IMEJ-2-2122-------A j**E*CBEDDE969IHHDD-DZ44JYDDDDDFdUXXWefeRxc*gdIEHPMKLPSDCI11XXuC*Pq***QD888L986CTDP48GDDlj*p-l773--B*HhZ*h*X*122222222111112EB3LKBCLLnF*****XKR*K******VabQSA7BGFBr*ax***i6A6665695665qXSDD587IPammpmpmorSqlqqppgocaTaqsvKVTxLPOHFEGFI**EHHGHGGEGGHHHGGCGGGBH8A6HH77549EF9AHHA997A6797KMLHFFHGEEEEEDEEFEEEECDCCCDDDEEDCCEEDAA8BACCP*cg*ggglkllZhUdrhhMLNJ*VhBDZalbF**yXTTFOJHGBMW77A*g*****DCCCCjw***mah*****QQOQPQPOPOd-********h*r6*************wyYteRj*zz*bnaNNNNNNNNOYWNM***55555566447C555555755553544445Mf*QEVZWNd*******uttl********X********5A******jj*****Rn**kkgf*d3455656NMfy**u***oh**T*****A*******t*******l*lGIG8BBBBBC9C9A99999rwLKXHG*uO****d**e*****u*w***s**y*u**--AYagk------gaZZWbSbeeebbcfac-eebaebdaabeccZabaaZefeVYQMPeacedgeededceceglZWUYWZZJ1dWXYYYWWXYYX--9T9A999HIHHOf*V*55565636556346BMMKMNFLHMGm******************421213212Xlqt*********************RQNQ22*E**adpo66676777D43-------------------------FH7FEBBBBBB*5Q ----DD1-121--1dDIJFEBDEEAAC6755356658777567757DG99DC8FAAAA9DCC876433274475644144466675644885I5949999B69DHM1CHQ121-------------------------1---1----------2----E----7-2-4--1--G22EDAj76685wRT*HiPE8a3237 * c.23.1.1 CheY-related
[  19] -------------2--2-11-----------------1-------------22---------11---- 15K-1113444---1----------1-------2-21221-1--2411---222211-------13-2331----------4---4--2-------*---71-46-713--------------7--1-1--------------5-E432--22211--1---22135435------------313----611-5555543515234431-----555---4-31----1-54--------------------1----------11-----------------------------------------------2------------22-------1-22-------1-1----1--------11-------52A-8211------221311-2---------------1-11111112-11-5112--213-2122--2-12-----12222222221222241-878BBAAB55ep45UU55Q533662N6f*-11511322211457515111122231111117j63333-1226122334422223352333--11211112212365528--2---2----2171623-1----7-2382223222222-E-------1--2111----31--12-5312-233-3---322125--2-131-------2-5-122331211141-412221-1214131111122223512------1----------22344--41-111111111111----7JDBAMPHL3171---------------13444342---2133332614-12122223111-13111--1111111111-2195696C95553343--8*HH96HF22222232A61------------------------------------23- KGIL***-*dd*uauYo*p**********uxqw*****y*xy*ztu************f***MKKIIHAIJNJFGJLCJJIIIIHHGFFNrlo*V*FHIGEGIjk*2*************************t******************************************E*****p**p************** * d.211.1.1 Ankyrin repeat
[  20] ----------------1--------------1----------------------1------------- ---------------1-----1--2------23---1-32-------------------------3-------------------1----------1--------11---1----------------------------1-------1-------------------------------------1111--1----------1-1---1---1------11-------1----11111111111111--------------------------------------------------------1----------------------------------1--------3-----------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------1--1----------------1---------1--------------1-----------------------------------------------------------------------------------------------------1-------------------1-----------------------------------------2---------------------1111-1-11---------------------------1-----1-----------------------1----------------7-----------------------1------- 1--275*-2-33333222334432223333333353433333323334535344333333332---1--121---1-----1---1432333253211111539CD-O77*************************************************u***************-131Q111-21--1541--23444 * a.7.1.1 Spectrin repeat
[  21] A88589JGFGGGHGIGCA99A68KOGHKJKH95A7966989775A7B877FFC7AC6CCACBA8A166 JPSJ*IBHIILEDEtddUW-Yj77**UVUUTatnpn*l**FmgoUOJEEIKBimlJIV33xveG*e*x*vN355566642DEb76532776527552126GBGJgFVLI544444433333344DFBFHJBBIHCRPPOP433QQdPURPQLJHMLMKMOMLINEQVWZTHHFGGHGLIFGIGJMED563ILCLLOMOMNRFOQNONLIOCBCEOPQ8EDHDOOC9AAB8UPDGGGGGGGGGGGGGGEGEIDB384AA45533GG6679A57BB4899A789668675677747756577889978899988687777888B5778HGGGIGFGFG9A8FE7AB7F9875C17DBHDHUA98FDECB97872J8NtaaQ89A7AIS***QKKaTVdUNSSWPOUPRUq1ZZwYc*Zpd*V6*uvrus*w**zyodNNMXntYWVamfwKKKKKKKKRSWKLEJM55634444452344444444444443333HJf*N9UlePi******iaZaVyy**ilkkKf***jyyn9IeaiUTYTQgXwXsvMLLFDBDTCBBB9AAA97GQYILfZFHIIFCHLDEC4BBABA89A9GHNIjrEa875536667533533333337587BHIMKDHSYcEWJMIOQOPGKNHHGELGOOEMZ217FAFH111111NIGMFGLQRRMQNNPQP-RPQQQOOPQQROQORORRPQUUJJKLHLJKJKLMLLKHKMJKMYLLLMMNO84HGGHGHHEHGHG453G9BA99EFEGAPVSeBA9686966639889UTUVTGVHPERWnqmur*ruetvlkWffiFACAADAAAAFEFOFEFFEJJGMMPPYacZaORQBBBB55D8KK99FH44433324729-11-3-5-74254444384443---A858888878CG27 6888RWQ-aFB2DIS************hmgjniplfiikjkmidYa*************vuuDFL97C7G98LHLBA7CADHHIOIECE******mjWfTVUdYVc1Q*l*gkZiVeVNMONWN*sK*N**j4wa*IKKKfNUacDVLNMaNJqRbVVcj*rL*Yi*ner*JNmWN*tY*WaZnp*******uqqkfl* * c.3.1.2 FAD-linked reductases, N-terminal domain
[  22] AA99A9AAAAAAAAA9BA99899BGDDGEHFGDCB999AAAAABA9CBBBFHFCCCCCCCC98997AB QUWFNHGHHHHGHGGGGFF-FIFFIHFFFFFIHHHHNJMMFKIJIGGFFGGHIKKGFGDDLMGEJIMPORGCEFFFFFGEJGIMJKKLKKMJIKLLIABJLLNKLPQOOIIIIIIIIIIIIIILJJKLLKLJMMLPRRMOBBAOEJJIJKKHHHHHHHHHHHHHEHJJLIHHHHHHHHHHHHJIHJJFFGIMMRRRRRQRTQRRRQTRNMOOMMRRRMKKPMSOPPPPPPRQJMMMMMMMMMMMMMJLMLLMOIJJLLJIJJIMLIILMMMLIIBLOPJJJIJJJIGHIIIIIIIIHHHJJIJJJJJJJJJJHKJKKKIIILLPNNRRRRRQTROSNJLSTQLLKSLJKLHKKFHIJPRKHOLJMKKMNHKKLJUOLMRMKKKKTRVPPWNNOOOOQMMMNMMNMMNN6QQOSQPPQPXNHQPPPRPPTTRTROONOMNLSSRSQNNNMMMMMMMMLNNKLMNPIIHIIIIIGGGGHHHHHHHHHHHBHHHHHILMOLKRRRRSSTTUTSSPOONRQSUQQQQPPRRTSWWSJNQQSNPONNOOONJKONPOUMPNPLLLLLLLOOQPQQPOYQXIPPMNQSRQGWXWQVUYWTUUUUXUNOIFFGFFFFFFFFFFFFFFFFHGGFIKKRRQRWTSOUYaPQOQOPOQOPPNPQQPOSSK6LMNKOKIGKKKSRRTUWRXUUXXUUNVV-UWXUUUUXXUUXXTUVVUVTTTUUUVWTTTURSURRPUSUUUUYUUTUUUUPHYWTXYXWSXWYYHHPPJJJJJRRRQQQWRSOOONOOONNGMOMMOPQNNQOPOPOQRRQRRRSSTSTSSSRSRRLLLKKKLLLNUTUZSSSSSRUVVUPPQQQQQQQSOONOLLNILLKOLJFFFGFFGFIHHAAAAA-AAB9B8A9999A8999BAALOKLLLLEKLGLJL ON8FMMS8*NMBVVYSTQRTTTUTTQSTSOSQSTSRRTPSORSSSRTRTTTSUSTVSPTSPTPMRPONIORMPSRQTAOPMOQQNOYYXOdPTQNNOOOMMRLZbZ8Q*Bzjufvw*WRplWmY**T*V***K*s*OhWZzXf**Tghba*UZvavZbhQfcXyZaLiSZqVWiSWdgm*n*qhr****R**WXjWZWn * b.40.4.5 Cold shock DNA-binding domain-like
[  23] 995477778777897A7A76885ARIISGKOG77634378797BCBGE58TXP5AA9BB99BC96147 BXdC*FDIJJIABBYNMHJ-HM88TWHHIHHMNNNNfogdClThm*egQpjBmhjbaZ22z*eE*W****K9EEEBBB94FEO33322KHRL3N67211DlEMLnDa9L111111111111119A78788476BAPOOVUDEE*9*GRNOMB89BC877553DH9XUYfE575655665565pUtDD643D8b********i******nuhhjl***GIO*imrVUTUTS**UTQSQSPQRSRRRRSRONYYTEK8VWADIBFRRFESUDJIHJDPRRNNNEGGGWGGOOONKMPMNNNAC9ABABAAAA9AZNNFDALLLC9dibpaYZedoeSeXFMKJCMPIsAGADUHL53mhI768AC6183BA5JGL4KYXWa33225RLqjnJFHUQPNXFFGGFFGFGGe-KHWLPaIVSuL2*opoyxm***eqWPJYFJhXPJOOOVW88888888JIK8EDUJ1111111111-5427714822133111134JKJJ8ROLDQhwyw*mfUVWTaaeababfHV*dXRPYM67OPKEDPBBSCLGWCBLE6A27vC687777765EDEECTSFE8BFAJJ87A2EEAF85A9DEDIGnoGF6367267674327222222288426EDlfHHGMdKQDKafhfdfPPaTUZZWXfbYo--26B9G1--111TgbZGfUMOOKNLONMM-NKOOOPNNOLOOQMOMNNJqvmTTUWROJOPNMPMMMOTPQPQwLIIKIJKF-UKKLJKJJKJKJ--5E68667LgSZ7BpJj999A79543455549PLPVRIH7ACGEYbaZg*pkUWVYTLckiB554565556TVagYWYTXujetnceLNKOOKLM656511EKCC77FG11111111K1D----1-1---21----1-71-12226G655353325OEH C8ABrnN1lJIGNOWkhzamrvpujqoddcicicfajohlelmVWXqj******bdlYbcbaXLJEIIDJFHKFKIHCOKIIJLKLNKMXuXhageKLPNWKRoYbAS*r*iscajYOROUQZR*yVoT**k3pZ*KVPNePRWUGSKXSZHKgSQIXqZVbN*VWLqYisfmmlLikc*XYXdRvWU*opfhZmWVdW * d.108.1.1 N-acetyl transferase, NAT
[  24] -------1------11--11111--------------------------------------------- --------------------------------------------------------------------11--------------------------1-------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-------------------------------------------------------------------------------------------------------1----------------------------------- eUad***2*ut*u******bopoeilaoohjbmjspkwotfquddd*uqnsn*vmqjjnntrgfeVXYLaYbdfaWWHUZZcdZYYhhji*w*w**hYdfV*d**qJ*************************c*********************************x********Y****ojh*p************** * g.44.1.1 RING finger domain, C3HC4
[  25] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- B89B***-hIF1YV*PTXQTSSSSSPRTRPTQTNOPLSNPLRSUUSPTSSRPRYNNSNRPQQSMMNKO9HPJKILRSGQTMMMNHLRPQVkVTcXgXTWVLUU***4********************************************************************596AP663A7bVXmXiJIL***** * b.55.1.1 Pleckstrin-homology domain (PH domain)
[  26] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1223--Y-1--------------------------------------------------------------------------------------------------*--**********************o*********************************b*v**Uy*8---1A-----1---------11-- * g.18.1.1 Complement control module/SCR domain
[  27] -------------------------------------------------------------------- 1-------------------------------------------------------------------------------------------------------41--1-----------------2--------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------1------------------1-1------------------------------------1-------------1-1-------1-------------------------------------------1---------------1---------------------------------------------------1------------------1--1-------------------------------------------1---------------------------------------------------------------1-----------3-- 2-------1-----1--------------------------------------------1-1-------------------------------------------1----**********************U**************************dks*********Q**W--------------1--------1 * b.1.1.1 V set domains (antibody variable domain-like)
[  28] KKEFINMKQNPPPPPLQKbWbUTOWJIQEQVO88GFGBBACCCKFADOBTOHNCJLMNTHIAJJFAA7 NKNIxFIIGGHHFDNNSPP-PYJJUWQQQQQLUaUgYRMSLZYkXREINMSDSYQEHH99YWZEWMXbhXHEDEEHHF88MIIJGPEESNRTAGFG934ALDCCGDEFBCBCCBBBBCCCCCCGFFCFEECFFGJWSTWWJIIXLyWYSMNKNMJJKHLIJJKPJLVdbPDHEEFDFHDEHDKKHIFIKBVJJJOJPRGKPHMSRHONIJGGJKOLLKKRNGEHIHHJHJLKEHFFHFIGGJFFHFHBFECDTDDAEFA9AABCF99BA8DCHD9ABBGCKACDDFDCBAAHGGCFDBDEDDDCCDEFHCCCIGGDCAKCGCMIJSHJIIIJQJPPNPYQPKJIJQJTFGHNZMMZMYTUFMMOLLNLPIEGPISXGHPBRHGMOJXTiVKUSSLHOIIHJIIIIIIW2RQXNYSUVZZRDXXXdZSUcYWYTMgIJFMFNOLKJJIIGGGGGGGGLXRKGIJMEEEDDDDD99K*FDEFDDJFCEFDDGBGI9MPUMCFPJFaRNPOUUQMMOKUUcWPRRRKUOofMRSYACebYQfVcTYbbbTSROSQQNWNFHIIGGGGJVJdMRHTSLPNRDDVLIHJDTUVXMNPSdWYSVWUUOFEDDG9AG9DCDAIGFEGAJGGGJEJIKOLGRKKGLJLLLMUQILORKKMIKNKLRJ84CONNQ564555PKGRIKQGLJGGKHLLI1NHFQKNNHHILKMHGGGGILMNQILNONOHIKLHJMLNRJLILOFIIGFIIF6QMNPMNMNPYJI77WFFFFFFPWTXIHYIJCEEBCCFEB96BGFCHFHKHBGDEDRLNXWRMQPXPMKLRNXUSCABA9BA9AHKQPbLNLMNSNQOOSQXUbWZLMPIDEG67LDBBDDEDC9988989FBD7GG4518AAB884A989746B8666BFDECHDEGFETHB FCAHJDB1lIG9FHK7CIJKECEPCHEFFHHGGIFEEGFGHGGDDEEC9FGFFGEBHECJDB8BCBBA4BBC8EBCC7FDDBBAECECEKPECGFMACECBIFJOR6GdDnNLMRSYNQMGOJJSPHfM**V1VNkJHOPSGJQOJOMLNMMLdJXLNPHGSEbgHJJBGaFHQFGWWF*JEMJEPZY*EXaCBYZWSH * c.37.1.11 RecA protein-like (ATPase-domain)
[  29] CBAFBEUDHGGIIHHIHDJJKHJJaSPPQEVPEDMNQMPQQOLMJHJLILYXMPJLILKLKEDEC1AB IGOFYBFGEEDBH9POPMO-MXEEQRNNNNNITRPUQZdXEYWbJDEECKJBMOQEBF99LLUFMLOSSQKCAAADCBABGJJHDFEBIHQQ7KDF51-AHCCELCGIC656655565766667QQPRRQNTUPRYVVVX88CQEmgacZacMPKLHFJIFISXMQpmpVHEFGGGGFGGFGKMNCCBB7LJEGHHHKHOHEKJMJMICLGGEEKJJHIFNECEFCCCCDPPDDDDEDDDFDDDDECDDDEFC8878866787AD89898E69A756966965658557566676666666666766686669667777666GTLLRNNMNOOMIMMPISSJHGDNGLABJKNPQdaXXSUHNKPKMKHEGBJLPNIIJ8DB8DROcdkSHKcaQTZKLKLLLLLLKR1XcdVciXiQVJ9RSSZcXUgWbWUPXNJFUMSWWWZRNMLLLLLLLLRLKGHTMh786777776655867767A88777765667DIMFDGJHFNXWXWWZSMNNMXXiaSQQRMTXifQWaY9BSQRPWNRMRXLSTIKKcMPIMMMACBBCBBEJHTTOGbZPRQVUNYUWXUHQONTPMYUVNNPOSSNXEDBCBBCDBCCEEFFEDFEFDGEHDJJMPKJOIKCKJFKMPQPGKNQMMNKPKMNRN7-8ITPO573767LIKOLLIILNHIJHIMI-MKHLJJIJIKLIKJJHIIGPQQKHJHJNKHHJJILJKKLJJHIMJKHJHHKG8PGGHGGEFGIFE77I999889DDCEMKPIKFEEBECDCBBBBC9CGFIHHGJDHFYKNQQOOQSVMQPQPQVUSDBCBBBBBBGRVXXJJJJJXOQVTHGKIJJIEEGEBBD88TCEEGFGFNUNKAAH9D7633334-3374353333348332555DCFCHEEEBCELEE CECBJIN4fFCDILJIIIJLJLJIJJIGHGHHHIJIHIGIJIIHIGHGIKIJLMIHIJHGGEIGHEFFDFDBGGHGGDHGIGGFHFHHGHVIIJHOJIJHGIGJKK9N*MaMUNMLKNLHIILLWRGYJ**U-aLfLOKJPMJLGEILFEKHIPJJMKPMbWFTJTIIGH*GGTGNVYR*USQYQZVjxJfXTWdlWRi * c.37.1.10 Nitrogenase iron protein-like
[  30] 555669NORQPSQQYN9HB8954454793566--21121-1113647334B562C988CC7RLI7-22 58KCu349CCI453G66CC-CC44EPCABCB7FHIIOUdi8G9QII8C9AC4RSRB5M11SZFAbDWSSVBA644OCA1188I24435EECA1E112--1D96AL9A4J22222222233333643634424672IIKMM443HDHABF7736623558AC6A667MKK7375333373353ICAAED98LDQgfjflegmQjiihbiPPOOJShibBFDODKIEEFFGGqYCGGHDHGCGGGGGGGGEGCL3BM9EG9BCAKQNCEHH38BJKGEDE5558A75858877A9697867434454464443396588A55527A3JJ4444555948A9EE156481363C3732ML8466947165H9744A27JFFK4H64FACRFK5248A8996879568655E-DDJBCMEJ8CK1LEEGLMFKGLEIFA9JGBAFB7ABD6B86888888DBE5686B443334442288BAFG9CJAA8BAA333428JHB1A896AWVVUUUPMQQNNMbYQRQPENbMWDTOO49NJM87CB8B8D8FF5888495H435334335489788DF6454247823427238344338BD9HF3694363AADBB946546533555455998A996IF5D36A99AABA58884985C49E2-5353612-111XRQLDSBQSSPQNOQRM-PMPSVPORUSROUOPNPPMniiONHLIURQPMURTUTQSTROTQLJLIHJO71DBCDFHFCEFFE22239A789FIEG45BAF645628233223671GFFEI9E546ICMNOOHQNM9RQSM9MLKKFODCNFHF367896779789A9BFED9GBB79954441174AA445521------A12----1-1132111222-411-----CEA778A8A85I5B PE6BdbO-*QN99GM*******z****ecVYVXqnlXdZbejfacZ**t********tpohkUNXIPP8UMNgRcfZJhdCOOLPTD9AY*f*ifetgqWORRfRe4D*P*******tdkpqxw**g*r***3*w*jimq*up*eUrnpgohj*w*u*****y**m**mw****q9MJN*EJLIQpy***xeal****x * f.38.1.2 LacY-like proton/sugar symporter
[  31] 776268754455544A38DBA9AEF678A5H72-211175775239371BFBI1DEDCDED8966--6 FEHEZ676667756G6633-3F117U333336FGGGGTSQ9941HC9F2GH7OLHA38--ACR6MHcedXD743377776LNJ33---EFHC-F22A--4MAC8MFI4E433333333322224222223112B3DIIBA556GHQDGAAA666667777DB794BGDLG585555585555MJBCCB99KEMkkmkmortYnlnuqrFNVVHbrkqJCGg9HDBCCCCCmYACCAAACDCCCCCCCE99CE69C5885C666MMAA8B7AB7646665553333233666666666661111111111111-2277722263IHGMCCCCACCF8DABOOCACDCI356838B6UTBL-5AECC45656M8F-DPMMK242267CjTZ84JTSUTLQQQPOOQKQMj-KLYJKXISM*D3*ssdqyo***uqYPHG9dxhdYfeps*EEEEEEEEE8AB3KPh--------224422332222322224-61WBEKBBWlfPqivvwtmVZddZnnmuigijSe*fhsqsn4CkkkSWjVYrXieqSJTY8FDJgW8BCCAB997BFMNCGa1WIMONMSRRS4O7O88J889PNLPPJ5AFDHBA9989872822222224E42255qdNLPGZIMRbPTUURDLMSPPHMLMOHML--338552--111RKSQJVSQOPQQSSQQP-OOORRPOORQQQPOQQOOPdkoSTRMOTRPQOUVSTRTRURQakLKLNMOHB1YQOQTQQLQTTT326G47266CGGG6BnUsDDGBHI4DDD9C67FmhihqTRBLLJCsrvqf*hrjgogeXPVTDCB8AFB9CAXVVaORRQRnbhgeYYQMKKLDED4444--6HDD6877--------B2-----------1-----1--------A82BAA9AA81M99 E5ACQKP-aD97IONFMLGDHHGFIGGHFEHHHHFEFIDGFFGFHHDKILLPONDIMKLOOOHBC88B7C9BEDCDE7CD6DDDCCBBAPULMPPRJFIJKIIgdX4E*W*klaZiQIFKJMbMrhFfH**o1kVpAIKIeMOXQGQKFEXFBdCXOYUcaTGIHJ1QCESKUSTQgfV*ZZY*b****M**nf*vvyl * f.39.1.1 Multidrug resistance efflux transporter EmrE
[  32] ------------------------------------------1------------------------- -----------------------------------------------1------------------------------------------2---11--------1------------------1-----------------------------1---------------------------------------1111122211213-2A1----11--------2222321-------------------------------------------1------------------------------------------------1------------------32----1-1----------------3--------------------------1------------------------------------21------------------------------2---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------1-------------------2-----2------------------------------3312122111------1-----------------------------------------------------1--1 ----aT*-E73-wu*PQUQUUTUTURRTTPTQSSURSUPRTNSQSTUTTTTSSPRSUTUSSUQQRQPPAPSQSQQQRFRSQQSTQSPQQTqUQfYnTPSTMfV***-*BG**********************z******************************************--2-----2285EAU54-23534H * b.34.2.1 SH3-domain
[  33] -----------------------8fBBJ5SOP--12-133335AN-EH8PG5B-1-1111-------A Os*7U466778645ACCAA-AG44BDA88998IFGGBEHEALJNGA7679A7ACE45711IHc4d6IUSUB444475558OAA458AAmm*f-n543--8kAOH*n*ft111111111111112A83CB69JJX7ssolkMAE*4*j**ihIJMGH655CC9ViIe***W554554574534XNF99354IGLZZdYdbcdNeafigYMOIHIGefoDJJV9PKBAABABwo79989888889998878886A676BB645466655BB655665575BCB75677776666667666665555666676557445524347AdOR*TTSWXWWYTUHgcbGJLITNP79FJNN8kiXNHF68C687A9537pOfymmk89999US***VNQnsjnrHHHHGHGFHGN-*y*t****Nhb5feeiihanvmcYfiUMYQHUXTWXKbMGGFGGFFGHIHCF*gg33333333335A335534433444422224CQaFAKMJGPqhkmsmjSTUPji**ZZZbIaop*lmpv28cgZ*fmPQ*pgmlFVZmNMLLiM4444444DDMUs*h**eSS*kF**wt*4*******U*******OzW9CC8666657454444444WXCESDDcQDhamgHmXLeRXYWOZUcYXUbbVcWji--5HMLN------NLMMLLGMMMPMONQLM-MOLLMNNLLMMOMLMMMMLPOQILHGFNLMMMNNMMMNMNNMOSJJFKJKMA-NJLLNNMHKNNM--4E77777BCBBDT*Jk444433132233237FGEFH8GBFBYXww*wu***jy**xx***322213312HQTSdYZYZZbgggjrqnjojkbdeCCAC11*7ttMQYX44334333412-------------------------8D777776668*4D --1-FE1------1RGIKGFDEEG9EB5544343445555555555HHABFGBKADA88ABB432111141132211-11133343333683I4B28798A5598C-C1S------------------------------------------------8----4-1----2--6-1775U12224r8EfMEL71Q3434 * a.30.2.1 Homodimeric domain of signal transducing histidine kinase
[  34] 76-4--CKPLNOQLMF2195753RH778429D54A1--66664BB9DC88978----1-11777---3 6AC9*CA977AJBG***kk-j*GG**kjjkjm********5yc*855B6I94HEREEP11pdQ8*e*pk*J4344444-6EDN32432CB9A-A431--6K554o566611111111111111256568536785IHHHI555*9ILK7LMR2233333533633AVItA333333353333A77CD1-3FAjGGIGJOENHHLJNSF89KKOWGHUCLFJE87444444z63888888888888886665631212212121172222121333444223324218612221111111222222222322212212222225---B3333C33142Y3AA1-1-3-921C42C3HE94B5-1F71125-22D5ARFFQ11111BAud*978kejcY46674465657-IHRJIWFHENQ-FEEJABCC9FRBJYAJ8GIQAEEEFHP44444444D9336KEH----------111111111111111----4GLiH1BTRGQRXZYZfsRYYMNLTb***yRnjQpku*g56MMWGKLLHkIRWie54K4144L8222222286FTIK7xYQFDHFCHEBBC2DED7F99BCDFFD*fDG33321333332141-11-111442732EG38EAD8B8AAAAAAOEDAAABF9DDBFG--16DB4------L7WF987AAAMAKKDBA-8BBBAACACD9CEA99AAA98DRDx*797889A999A889889D67788871-8BBCCC9888C9---646665BAAA7Eg6O333263133323334EEFKE6G9BAVFcgYdzmknKWRXUCgV*7444454542677JCDDDDBD8BC88967666665444--53AA44662222222241---------------------------11-------2H25 F767cfF-fIA8LKk***s********ljloon***vmrnpqojjg*o******zi**iWVVJ8C9886CA8A8CCB8CA9BBBICDDDo*Y*YbZA8A8ECcdde3O*W*o*i*fsceaadYe*sW*i**m9wd*XcgcfeYgTRTbZWpdYjcYYTpWh*P*dprkPi*XduO9GGI*EDFLHbkk**nxFHkZYVo * e.23.1.1 Acetyl-CoA synthetase-like
[  35] ----------------1121222-33352334424-------244224224244-------2222-22 89H6622444442247844-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-FDFFDEDDBEFDDDDDDDDFBB9B779DBDBBBDDFDCDDBBB9FHCA7CD75999999979A99555A666668888DAG7E888888888688888AAADA8C998DACCCCCDGCCACAABEEE4444444446GFDGFGFFDEEEDECAAAAAA999777786A67777778888888856222224-2222222222222222222A89AAAAA9A6956 UVRS**j2*nkLQQfmkidjjlchvhhegehfhfbdgegfccfdbdmoiqut*zdilngjhledeeeePdghccksoVpnccccccfbch*ek*i*gaaWdaW***Ed*************y****z*****5***r**y*****x**vy*sz***v*z***t**ul*gelgs*fOVhQ*RSRVU****h**Ycxvvwp * c.55.1.1 Actin/HSP70
[  36] aZ9QJajOWVTVTVUfBEbTeYXQcPPSKUZUOOhWWWYZZZaciQhYXheigRIIHKKKKKGGI3AS 7FD3H87GEEE7BAAEEII-IM44KEIHIIIAOPPPKFJHAJGMCEC7IAB8KGG49A22OMH7GLSNdTI644466644A5IA9JFHCCBD4G682--ANCFLH7FME65555556657777ADDCBADDDBFBSSSVW667EHfNVPJKJFAIIA88886MDDGccWG574545675476D98LJ883BMSOOOOOOMPOOPOQPPLKTSMUOOQILLKPNIJIIIIJQIHCCCAACCCCCCCCACDCDEE888FF85868A888FFG98664977DDDB777ABB888888888887777777777777C66886666A4OHKOIIIMKMLEID6GRRIFFFCC895G66MLPSUWCIHOGE8654289DGFHCCE66666BGVLOSFDKLHHFBB9BBBBA9BG-EHQAAVCGMPE5PKKERLVRKISUFF9C8E8OFEFFBCF88888888FHH88TII55655555666666466665656655555299E97EBB9DSLNLNNKIGGGRRMZLLLL9LMTNGVIP6AKKHJAIGJHIIPN89DTKGCDPL6666666DEDPKRFadXMWfQFmVVRQ8FFDFFGBLAYYlaScCb743334332462622222227A34788MJ9KOFMEIMIMNOONDVSMKLPQOPKPQV1-7JdJJ442333KE989IEDDCDDDCDDB-BDCDDDDDDDBDFDDDDDFHHHAACCCFFFFDDFDDDFEEEFFHDCCCCDD72FBBBBBBA9BBB556977767AA89CFNKL777666766645886AAAAA9EDBBICNLPNHGJIMJIIICFGF965646646JLROOMLMMLLWRSTGGDEEEEABA7666AAQC9977BB5665555599622222-4213422333-2-243444CB9AAGEGGG5E96 13--rtX-LA75KLbFFHEGGGGJGDGFFEFFFDFBEFFGACEFDFCFFFFFFJDDEDEFGFBCBAD62B83CBB552666BBBBB7B9GIBFC9CB8ABCD9Zae-QcWYstdukeOJNNMfM*uJhQ**o2hg*JOPFlJTZPBTPGCmIFlQmMVXJNMXPJNA*FLOZhJHEGIV*NMKLN*p**GupORYnjhM * d.37.1.1 CBS-domain pair
[  37] 99743778987888877D8A877AB88E9BDB9888CA89869AB8ACAEBED6CCBA9BF887H-AB ENSCWCCCEEDAD8QHGLM-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-IIHHIHIHJHIIIJIHJJHOUPMTOUCIGHGFGHGGHFHGHGGKGDCHHFGA6CEFFFFEFFFFF2379BCBBCHGGGGHNJNAAA98B68866A669EIHJFEGCHCKDSRRRReVaKUSUQHRVWHBCBCCBCBFGEBFFGGGGGJHIHIIIIJIJEEF888888K9MMJJKN2222222263211111-1121111111231111---A999A6A676DGBG 6522GEG-H644DFJKOOLRQXNlYiXNNKJJKSLNJOMNMNLJHIPKOYWZheTRMMIHHHJHHCEKJEDDIEJIE6FGIGFGFMEFGGVGOKHFOIMKJOHMPN4J*LfRXMQPOMIKNMJMXQLeOz*T1SPfLLPPNKJKNIMONOMGISMOJMPNeZEZINJNFH*FIQLMOPO*LJKOPgm**NuRQQfOYRb * c.67.1.4 GABA-aminotransferase-like
[  38] 11-1111111111111-1-----343346321-243331111-44-233252321113222112---1 3441211211111112211-12--3111111223334355-1111112----112-----331123335211111-11--1-1212212224-222---1145411-2----------------22-21211-421111-1111-9A68556335533444345234554143211141211113------31334343353444444142112424222143311111111--------------------211--1-11-21111--1-11-12---------111---11111111--------------2211-222--31121111111213-1112------1111-1-11-31--1--------11142112-----223211--33422------------353341-4131-1---132324232342252--1--323111111111111-32-----2-------------------------3211-1111-233463-1111113422221242233341411112----31-1---6-11123---------5112-5523232165112-112221133----1-1421111-----2111111111212452232-334423433222223633344255465--11222-------1--22-1111111111-1111111111111111112111--1-1212111211121211211111111--111111111111---3---------13434---------------22222-22244-222212123212243112111-1--123234111114645522222222221111--4-11------------1------------11----1---1122211111111111-21 9423A5V-NB6164B76885AA9A98966442456654444447767766658656753787964366-562646662666566662447A6687BA779856FIB-9*J**********************D*****************************************q4qnf*TXTH7WYS*8oJaa***** * f.14.1.1 Voltage-gated potassium channels
[  39] --------------------------------22---------------------------------- 76M-*32655A1--W9988-8U--9b888886bTTWuq*g-H4nLZBB223-MEB325--OP9-e5anwj27---44252J33-----****-w556--D*FNS*P*4*--------------2--21---12D145451---O-k57C114----13-311A8-HCiJ-------------45---44266AFFHFEIDL6EKJEIHykMKHOJIK5DCf96CIIGJGDg*2BBB9BBABBBBBB9799FGJ993-162657FD225323B4CD557795A977966777565677764A77449757766D7722-7774SWQB*hehcklfKfEzfNM7IKJ*FHB75Pe--tZ84227224714c-48M-XiHHI-----VN*lm326cNETGILKLIIJHKJY-TLUNNdFhT*I-*zzj*z****x*XI5DKIQpI6FIKTf66666666F9F4855T------------------1-----------2Ez41HTNHo*******z**n********R****l*zf--eefHJHB9xEFE*Q7i9-A6HeG55555555328YC3F2342267DV66F-8B6424D64AADEP*-2H15411111-1---------4E3-722aVSBTde6hI4FRPQQI8JUJJHPEJRFNf----1-2------kYngJrIfooihfjfkb-ndgnfgihhkphmfgdjgZ***ioPQRnrdjihlifkkkojjmxXVRVUVXB-XWWUUWTMWRQR--27-3---44639K*c*84384G-43441331degieHe-84VF*************cfaZ2111111112PSSiNMMOMWjjincvQPSPNB9B2222--3-LN46A9--------8-1------------------------------2-2222h1B -1-----------8---1211112221111111111112111111121111-11---1----222----11-311------22212------------------------------------------------------------------------6----7------1--12----------Z--9-----C---- * a.4.1.8 AraC type transcriptional activator
[  40] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------17-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------ BBMb27A-B--------------------------------------------------------------------------------------------------p--********************************************************g*mr****h---54182B6111---3-1ces*- * g.60.1.1 TSP-1 type 1 repeat
[  41] --------111111-----------11-1---------------------1----------------- ----1111111111111----1--11------1-1-1111-1111111111-111111--111111111111111111------------------------------------------------------------1------------------------------------------1111------1----------------------------------------------------------------------------1-----------------------------------------------------1---------------------------------------------------1----------------------11-111------------------1------1----------------------------------------------------------------------111111111111121111111122121111111-1111111111111111111111112222222212111-1111-------------1---------2211---------------------------111111111111111111111111111111--11111------11111111111111111-1111111111111121221111111111111111111111111111111111-1111111-1111--11---------11111221111-1111111111111111111111111111111111111111111-1111111111111111111111111111111--1-------1111121111----1---------------------1----------31- PWNRdf*-***bkdtKRSQPPQRNLQPQPOQPPQRPPQQPPTSOPPSPQMPQQPTTRRQRRQOJKHGG8GJGHKGNK6LKIGIIJJSOQSlORRRSQOOcNXP*x*Ct************************b***********************************x******A**y*YYbnp****Q**k****** * c.37.1.9 Motor proteins
[  42] 551312-1211-212-3-556564F3449-6A----1------111-9--1---1111-11---6-41 ADE8*339BDG22223311-18111V11111198889HVVFeE*erZ1PSL8hZf33E22JFWCjBZpreBLGGGQTQ7---H-----879725121--2D163E3H5H-------2211111-11223211431GIIFD222SA77875573422211332434277B912-11113-1-1MM997KJ-JGFFFGEFDCG9FGEDCFJOJJHFFFCBOS6DCCBCDDBCIr64444444444444453278GBC5DD5E74AIICCAE978EHA988DCDFDBDA99AAAAA9AAABA99999999999999CC887CCCFGD7Bw6666676D7ECC336CBEZ8882D2I74885A95S448FBFJ56952CFDD412212H6***63AdIdgPOQPUNPQLQPl-CFiDBrEXJ*2-*ssk********XbC26STZOKNQSJP33333333YJK35E4H------------2222122112222----44A582JYSJUeimlpgQLMMKcc**TQSRIVec*QdcN15WXWf8PKNbcmSu*8BB-5-3DA---------1AHM6HE366C87JL779345471831255545b2M2--1-222222---------122--11IIR88DB1C5L99AAC48A9893668638C---2212------ZWXTBaMQRRRQSSSRP-RPNSTPQQTSRRRSTOTTQoooUVBEDNNKLLMMMMNLKMKKKlLIKJIKNC-YcccccdZbddd---111111223433TEYAAAE8G27898ACGD------4232RDCCCCBIHUCHDJEBROO---------1DCDMHHHHHIIENN98BBBBB99A2222--8C------65556544437----1-1---1--2221---21---CEJC68SAD9-Z22 ----214-A7y-24B----------------------------------------------------------------------------------------534-8iB*******kaefi*h**b*m**w2*p*Yibf*dhrVSjbeVvWR*fhav*BIGg**aXiLO*mt**-41-------EAB*-M41-5---8 * c.93.1.1 L-arabinose binding protein-like
[  43] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1K-2-1--11--------1111-------------------11----------------------1---------------11-----11--11----1-1-22-**********************G******************************************-11-7-1-212111-1----122- * g.12.1.1 LDL receptor-like module
[  44] -------1111-1111-22-2-1-511343212----------2-215--33--232-2-22------ 64E5M8CCGGG95987A99-9933BD9999989999KNFE3H9QIJFEC977ACF38F22CICAQ5GQRa78999898G5XF2222117853-435B--3C755E5D7A1111111111111127568B97B988788AB322I1IDHJAAB4488D899B99A8FNWYC6C777869676755822D83B39AADADBDE8CCDCCECEEEACDFI4579DBBEEEDEEHO86666665666666675456MK6DKLE4JEQDD55RT96467BC9B8ACJECEJDFDHCEEAEHBDB67766677A7766FKHGGCEEG9H8DCEFFFFIFE5F9HCHH5CBDV99KPCFB2-TTE2225322BBCF67591588854545674HHGD896GBECBBBCBBCC8CH-IJOIKHMLAM74NIIGLOENNMFIFC67687HBACBFBBCCCCCCCCB796AA8G222222223346446746655544533521468236997DAEEEHDB9AA9AA9ADDDC8BC8BD8B523668C8985A798D89CB4B48A636447448789A67573736648722213635567383363BF19756454444442133333334523488BA8B63A386A7899787778889A8E978--74984222222C8BA78A8AAF8DFC88-A8888898AAADB88888A99EFIGKBBC9BABBBBBBBBBBBB77A777853GDFEFFDCDDFD11422432279A742D6E7567893787635595667667448BGBDDDGHBC9EECC4BCC6545475353988F99998DBEDE79C9AA999A44443293884444--------v-D221261532366366543935533365C767A7872725 E9PWhYR-zQBCiieVbcWekuh*zziRRKNMNkqePURTSTTLKIkgk*vw**jZpecWVWVMLCFH4MHANIRGJ4HLDEEFSLCFFc*JbciXQORZMKaomU5P*j*p*o*y*ecjfdha*xU*Y***1*o*YcedyZf*qWdWdPrcW*dpZjtc**a*aSf*in****yDSNG*ACDTJ*xq*X**OU****l * f.37.1.1 ABC transporter transmembrane region
[  45] -----------------------1N76D2IDB---1--112117G-FB79C45-----1--------3 Sp*7U55566765369A77-7E33CD788787IEEFEFHGCJFMHE775BB7BEL547--JHT4SCOOWU9544456637G4B12243aZvN-j223--4U5FDpbnWY-------1------2963C966DKM6knighMAG*5*ZmyRRDCA9A123565OaCd***S13-1111411-1WLC66434GGIJJMINRLLFNKPQQLLKIGIEMPNBGGHBFE766667iZ5554544444555442455573739933222554488543431242555644443455565555656333333333433343444144456KGBU999BCBB6A7DCGG63439CG21H66G5bYSKGA36943257222jJYqcca65666QQ*mrOJJfiedfBCCBBBCBCCF-yp*mvp**GVY5WXXVaYNglbTOPXJFRIFJRLTSGNHEEEEEEEEEBAAC*cd3332233322791133122112112222229LSB7DIHEFdVXZebZORSNZYwzUVUXHPcbuZbdg36UUUtaaIImcVYfDFLZFFFDaD3333333A7IOh*b**aMK*hD**tq*2****uutOm******IrF2642-------1-------LL53F77VLDWQaQDUIGRPOQPFJNQPPMSQOQMaW--3HJOF------FCFHCDCGHHHGHGHFG-HGFFGHIFFEHHGDEGEEFBEBDGCB9FDECFFFFFFFEFFCGLDDACBCG5-HBCEEEDBBEED--48555558A99AKoCY111111-1--111238A77A59494RLggkgfsnvZhhngoghk222212212DDJJWPPOPPOWUYYbaaccebSSU997911*4XXGJRR232121114---------------------------38132322135*4B --1-FE5-533-33SHLPNGGHHHEHE6666667768988878777INCEJIEPEGDCADCB7763533932776322324555783239B7L8E59899C99CCH-GCJ5576565543424455554DS5-7684554445642454245-75345D211562312-4211432AA5h22355o7EcPEMB5M7896 * d.122.1.4 alpha-ketoacid dehydrogenase kinase, C-terminal domain
[  46] 332231BFKJJKJMKF2A664741H66594B431----------311-1-553-11121116442-56 CEQ7o84CCCG456RaWSS-Sb99v*SRSSSTalnmdo**7cIncHJD8GC7QMQFCF11NKVBvEurhdG31113531--5N112111132-311----9-9-Q3B74--------------2432324332749CCB9111EFF97E5551134---33-333EFGM82----2------78588861F3HDDEDEDEG4FHGCCFDCAACBCBD6636FFA8888878E49A999999BAA99BC9A9D4-B-8D-A--2GG6678B4565C5453231222566444444445452222222222222433442333346218332433433385111-1-1-21-211--212141241233441-4A5IQGGJ11111LEcSZ94ETKKML89AA99A688F-KMLHKQGLEQU1TSSJZWXVYcVaKP9SAFEIJFKLJBN88888888EGI768DE111111111111-------------111149SNE65C89GXXYaZZUPNPNXXXaSSRRAMbNbKjWQ-3CDN9HADBMEKGOI9DD-333A4345445463AD865581112-132111-A88454534EGJJTW573----111111111211111-----56875FC9B9VDA7988A7E799958898698--17643------EG9D5DFKJJMKLLLJK-IKJILHJIHKIJJKKJKKEOQKGIB86FEHAGFIGFIFAFAAFOACBDDDG1-B88888888888---722122655538DOG333714-1332-24-99C8I5B6C8J5NQQPFRPMGKLKKGLJL411314111-789C333238A979DFHFIFF9CA6333--25AA6689--------1--------31--1---1---21-----24222253337932 -178z*E-NA5-69O***w********YYSVTVbaSYYWXUZYRQQ*xt*****w**xaaYZMJbBIIFKEITFQMMGLNFPQPPPFGFx*i*WlXXTULYEPUVT-M*b*VePUXOKKEKLZHbdLtI**Z1jXoMLGIPEJcFIKFBIKMJZIcMQlUWNBZQUWHNfVGLERAMOE*C9CJQlz*****HL*xrqO * b.35.1.2 Alcohol dehydrogenase-like, N-terminal domain
[  47] --2-1---2222223---11-11-----------1-----------1-----------------1--1 4472411211121143311-12111311111134442321343444321112223211112231326444311111112--141-211443322331---3114322321---------2222-1132122133111135---322111224231133121222141131343233322334232--23141111111-1121111122211111112311112211111323222222222222221223212-2222-23222--11-1--1111122211111--111111111111111111111111222333222143332111211241443444555211122-24222211121121125--353D433322122344354324244222222222222-453333332331422264153413--3121-221222-2--------3332333311111-----112222222222222---11234122112131111331111333333333433211-13233331342211331333331232222222222247442112333223222133534131299586C22112-211111-31233232331422333444325235432222333222231432321-2433511-11133342324334444434-344333433334344444343433212333333333333333333333233323333333333332233222112322325211112133121-211144434463424522223333322222333---------12112222222211134555553332222115144222222232333212------------------------------------442 221121*1944-4532222111211112211111111111111211-2233337-2222122111211122221111111---112222---21-----1---6671D*-**********************n******************************************4DAA*688A8F7DF2ABirj**xk * b.36.1.1 PDZ domain
[  48] 99BAB9AAABBAABAACCCCCCCA9999999999AAAAAAAAABBABBABCDCABCBCCCBBBBB9AA CCDAEABAAAABAABBBBB-BBBBBBBBBBBBBBBBCDDDAABDACAAAAAABABCAD99DCBBCACCBBAA9AAAAACABDBCCCCCCCCCBCBCB58CBBBBBBBBBAAAAAAAAAAAAAADAAAAAAAAAAAEEEDDCCCDBEECDCCDBBCCBBBBBBCCCBDDCCBBBBBBBBBBBBDDCDDBBBCCCHHHGHGGHFHIHHHIFCDDDDHHICCCDCDDCCCCCCEFBCCCCCCCCCCCCCBDCCCCCCCDCCDDCCCFFDDCCBCCBCBCCCCCCCCCCDDDCDDCCCCCCCCDECCCEDDEDDCEDDCCCDCCCCBGCFGHHHHHGHDHEEFDDDCDCKCDCCCCECADDDCBCCBBBBBBBCCDBACBBBB99999BBDDBBBBCBCCBAAAAAAAAAAB5CCCCCCBCABABGDDDEDCEFFCCCBBB9AABBBABAAABBBBBBBBBBBCBABCA9A99999999999899999999999999AAAAA9BBBBBCCCCEDBCCDDCCEBDDDDCCDDCCCCCBBBBBBBBBBBBBBBBBBCBBBBBBBBBBBBBBBBBBBECCCCBBBBBBBBBBDDDDDDDDDFFDFDECDBB9BBAAAAAAABAAAAAAABBBBBBBCCBCCDCDCDCBCCCCBBBBBBBBBBBBBBC7BBCCCBCBCCCEDCCDDCEEECEEFEEE-EEDEEEEEEEEEEEEEEEEEEFDDDDDDDCDDDDDDDDDDDDDDDEDDDDECBDDDDDDDDDDDDBBCDBBBBBCCCCCCFCEDDDDDDDDDDCDEDDCCCCCCCCCCCBBBBBBDBBBBBBBBCBCBBBBBBBBBCCCCECCCCCDCCCCCCCCCCCCCDCCCCCCCBDDDDDDAAAAAAAABCCBBBBB-DBCBCDBCCCBECBCDCCCBCDBBBBBBBABBB JKCCOOH1mFEBGGIJJMMJLKKLMLKLKJKKKKLJLLIJJJKJKJLKLLLMLNMLKNKKKKJJJJJJCJJIJJJOKCONJIJJLKJJJHWGJHHGHHHGFHJNOPBMbPfQYNUUbROPMRNPgdOXSz*M3WX*MROSZOMPMLNMQPMNLXSPNNOMWpJOLKNQKKhMRMLKKKL*MLLLLUQnnLaQOObYMNM * d.104.1.1 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
[  49] -----------------------------------1------11----1-432-------------1- ------------------------------------------------------------------------------------------------------------------------------------------21------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11-1--------------------------------------------------------------------------------------1------------------------------------------------------1111---------------------------1---------1-----------------------------1----------------------------1-------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 1---**g-521-TWXCC96CA9ABAABEDDEEEABAA75A49AC9BB5CBBBFB77EBCACEB89777387485888279688888FD9DXDCHCEBBDE6EIXgX-*P2**********************R**************************n**************d4-25k23312RUU*9cF--38676 * g.39.1.3 LIM domain
[  50] 66272678CCCCCCC77J877788F45IACD6989667766699A7978AA9B7898974A576A-7B GK*9U99DLMNA8CIPQEE-EV88OREEEEEHUTUUJRgcJKGSejb9BPIDgaiBEL55OLIETFSQfTC999988868B6G99998FEOI7V9A3557I8GQVBpFb555555555555555999A9899BC8HJJYV888DBGEFIDEDBBBBBBABBAEEAHIHLGBAAACDCBBAADFCA77DDAFBCJJKJKGJMBKIKIHJXMGGFHIJHCJKCNBDGGGGGELuAAAAAAA9AABBA9A6986AB8348B58663CI45AA589889BBB7778575978988999897984555544444454977665666ACD9BGAAAAAAADBCBECC9775KDC75DBB9AGGAAD9A888FDFD529GCkLDDE78878E8LMJA9899ADANNNMMKMMNNO-HFHGGDGHObA7eWWOcghkkgaXFCDCBHPJFDGFNKK88888888FGIAAC88443555663333222222222222244448CGMB9BDBACJJJLKLJCCCCKJLOFFFFBGNILGEJD77GEHOCAGCHFHFGOB9A9A89DA88888888AA7BE4GDD9AA99AC8888CDDAC8EBDIGHIDFAH9B9789988A89B9999999AA99A88DCGFAEBAHFGDFCCCCDCEDDCBCDEDEG334AA7D755777MHDHDHDHHHFIHHIHH-HHHHHGLHIHHIJGJHIIFTRSJLJGDHGDEFGFFGHFFIFEDPFFEEFFH85FJJJKKJFIJKI6679777778888AAHFP989B7C77776999DAABBA889BBPEHHEFFIDHFFEHHDIGH9333264339EEDIFFFFFGHGHHCCEFEFFCCC777766D999CCAA22222222237111-2-1111121333112112---6CB87DBEDEAbE9 551197D-NB74AGHLKMIRMQOfRbKDDDDDEEEFBDCCDDCDCCIEJUSUnVNNIIHEEE8CB7CAA89GC8EDC7CDA9AA9AGCDKaIKKKPaSUHEDFHHK3EqCYHTHJMFFBA9CM9n*9a8b*D-KDe5BACk9DO95D7B6EA6NCFDFF99DBUE8IOCHk9CJ7JHJK*EEDIIkWsgKbUVeTVQSX * c.2.1.3 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
[  51] -------1-------1--------31121121-------------------1---------2------ 212-O--31111--PnhKK-Kq22lgKKJKKKorwsRGRc2PEr2-1211--3171-2--SH8-aBaaISA----1------1-----------------1-1-2-2-1--------------------------12221---D-B752772--1111131131-446A6-1-----1----32411---1-7333336644443444226638333----1-1------2-1-----------------1------------------2-------------------------------------------------------1-1111111-1---------1--------------------------1-15443-----22IEC11-739A51111111-111-45855757389-344577924332213822922233334---------22-----------------------------------6GI6--11111112511333344253333-44162245--22121-2121423-----1--2---------2131-----------------------------7O-------111111--------------------2---1------------------------------------21------------------------------------21-3------------------------------------------------11-1132-----------------------1--1--33232221-2---1---2------------1-------1---113333---2222------------------------------------------------------------ ----jt9-842-99B************ddhhff***gjeigjjfaa************phifH893533A3394A3323339AAEC222*******55587ILetn-8n********xnnv*****z*****-*y*ky*x*yn*xUllyu*si***r*****k************5bLC*B9ARg*******ACdUXcA * a.104.1.1 Cytochrome P450
[  52] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--JU2-11--77K54F7877779778977876766777677596BA8CDAND9E99888884476533743456A7AA744435643EKE4IIE86666C8UTiBAbG**********************M*****************************************b745EKB9953****B*g6C7CDC2 * a.4.1.1 Homeodomain
[  53] ----111111211211312112211--1-11121222222222------11113-----1----2--- 3563M535897321B7532-33--6O3333254676DMWd-D38D3553653GBF137--766-K8bMOJ7-11113433493223222221-2-----1412171413---------------21112-1112156634---21A34533423331111113628545211111111111134122---53FAAAAABBA5AAACBBB5A8DGBAC232C472544545MW12234333333323353447434245343-2BB3377334335446222-11124311111111111-1111111111111-12221111-14CI444445444435663112B211394531KJ564314843221-23333VAAF11111bHumwA6KRREQGGGFGFDHFEGd-UapSP*XhV*A1***kx*p******pHCAMZmLGLQEhpGFGGGGGGKXUGFBAM-----------------------------17LgD9l***********txxr********d********27*ztYUsYa*b*V*jIhJ8BBFwH4444444443CYNI672535726A665-736849574FH8LGT2532221222211-1-------24433BBebYJGDjAOKHOYVaUFSZXSSPVVWWSbd2--464C1-----aTaoIZSWYXUWTURWU-YVUUbSPVWTYTZUUVWUN***igGLJVPURTUUUTUTTTSRR*PNMNNON9-SMMMMNMKMNMN--15-2--279897Ajhy888E6D376757546hhhjkMS9EDtD********n****Rtqz497458A596PYarRRRRRdidgZijVWaWVGHH51321-5211------------1-------------------------------------2821 -------------4---------------------------------------------------------------------------------------------------------------------------------1--------------A----3-1----2--5-1--------14--Q-----D-11- * a.4.5.8 N-terminal domain of molybdate-dependent transcriptional regulator ModE
[  54] 22-4-22622422226-2222224C4648888-22333333346646644A6644444644622-2-- SKg4S68AAAAA68*WaUU-UWAAnZQQSSQGUSOUKMKO6KGgC8887C8498869822EGM4G8ALWK8--------2624AA8EEYacU2b8E2--CbESKmSiKP222222222222228A48AAC88AIC4445564444GICCECC4466666C8A8E6UAGMA26222226222258644444888AACAC8ECCCCCCCC6688A8CCA868A6A8646666GE46666666666666684668-242222-22222--22--2-3------------------------------------------------4E28G222222242422884446424224468466C66688242227484U8YYGGQ44444SYsjygOemgkcWCEEGCGGCECI-ouabsimkCMW2aMMSQQUQQOKPOiIOQGCICECCCACKKKKKKKKIROMIGSI44444444442242664664446644244688IKAEGCCNYgigiUOIGGGVUceOOOOGQcUgWiho3CegaIeMKOmYQIOIOYaOVMQIK4444444MHSUZcISOECFIEAITCC84ISCKMOSKMQSOQcQ6QIA8668888888A8888888KC8CMMSMKCeaSmWaUEYaccaccqoccheYo*mqg2-4SOGO------IEEGCQEGKLLGIILGG-GIIGGIJGEIIJIGGGGGIQSQIG8ACFCACFFEFFFCAFADCMEACCAEE4-KGGGGGGECGGH224Q8A888CKIKiSWGI444466444344664IIKMICM666OOUWWYWUaaSaaaQOOSU644444444QEQQTFGGGGMWaUUacUOWOOIMMECCC88OIQRCGOO6666666684-----2-2132211222231122111664AA88888KSE6 336644D-62---2122232222222222212232322222222221233333323333333222222222-22212-22222222---33322242332233433-1h6*ONMQUCIEDAGMHNL9TCt*Z5ULY8FGEIHJNI5IFGDLBASGJMMU7Dc6fLFABDDfx*W7-438VACC42B22P24266K9D6J * f.35.1.1 Multidrug efflux transporter AcrB transmembrane domain
[  55] 44252699DDEDCED84B88898ID88D7A7CC9A7878887979AB7687A865A354445556167 BJK9VC8EBBE99AMNMEE-EK77HaEDEEEEMSNUKOZaDPPgPKID9IECNORFGK55MHP9OEZXcVD8777A773585G88777DDFC6I771115CBCAIBIDE22222222222222467666776786EEEEE555EBG8998888878777678877CBAF9566665565766CC988873IDJJJMJNJKLELJKJLJKHIIJLJLLGIICIEC888888OK9CCCCCCCCCDDCCCD999CC393BE39232DC77CA6868A7BAC4444444666699787775785555555545555666556666A8E3EN555565596A9AEE9665A5775G9785NKCC8G79A7BAB8224F9CJDDD34454IDbRQECGGIFJICDEFCEFEDDL-GISIHdFTNTA2ZOOMOMQTTQUTMNB9CHHOGFHJKHQBBBBBBBBOHGBACBB22122222111123221332133232131ABIOD7GVPGTbZYYaYQKKLIXXfaRRRRJRdTqLWQL7ELJJLGIFELJRNYP9BE8B78DD66666669A8LLF3IDF9BA77886675HCGAEACABGHEHFLAC857665445444645544556669597CAEDDAE9HDDBBCDCBEACBABBBAAACB325BA69332333IFIH9GDKHHJLLKKLJ-HJJJJKKKHKHKIIJJJJJNQMNLFDBIEIHIGIIIIIHIGHHJFGBFFGIA4EGGGGHGFGGGG33569999977778FIIJ888D59345447668GGGDGCF99AP9NQOOINPJLLHJNEHCH5575666558B8AFBBBBBDDADDBBFEEEEDDE766644A899ABCC2222222243411112-113111-1112231211112575586788AC8A 442356G-M961CDFXOSOPRPMcfZWDEABBCCCCCECCCCDABBKIGOSViZHHJFHJKJABA6793877A88DA6EB78888A687DKDOBI9IGHCCCCHGM2IuIeORIKOPFGFCFIGVKFXG**M1RKXCHFCLGHKBDHHFBHHFOEJKGSDKJEYIDDKARPHMM9JMOC*FBBEFXVgiMRGIJYMKLN * c.2.1.6 6-phosphogluconate dehydrogenase-like, N-terminal domain
[  56] AA242-GLNNPNNNKG24E8A84SE666628G222222222222222222222222222228AA4-44 6CIAjB2E668666q**VV-V*CCopUTUUVe****e***8yW*688A6646KKK8AI22akZ2PTbtehM2222222-222K222222229222222-9FBD8QIEAA22222222222222222225222222CCCIK222E8626A4672222444222464D55B4222222222222GCCAA222E8CAAAAAAAA8A8CAAAAG668AAAABEACE84444444IA288888888888888866686244444424222444442242466477386662222222222222288888888888882442224446248864444444444888864442442-C4464IG8C4E24E42242442G2DgQQP68888EAeVbEGIXWbVREGGFGGGGGEI-CCKCCWCIINb4KKKJKJNNMQMMKVFGCGKMGGGGEKO22222222E6637CAI222222222222444425422422422224LNzQ2ClYNdRNNVQRNLNNMNNUUONOOHNmVxTswk68STNNJJWUUOPgjhAAJ5446GA3444442666bPNAuHP92442274442GJG9QBJ7ECEAEZb8C244222222224244444442222255EE6CGDNCEPDHFGGGDJSFFDIGHOFGJH2-4AC64222222GAEA6EEEKKGECCDEE-KEECCCCECCKCGCCECCKKMKIAEHFAAAAAAAAAAAAAAAAOAAAAAAC42GADACDDBDCCC224E8A888EEGE7KLGR444262244244682KJQQKEQEGAOCVWTWQaTUSUIUMIMMM8444444444ACCJ8AAAAEIGHGEEFFFFFFFH45554468AA8ABB222222222-4-------------------------44444242222A4A 441-Xp9-MA62GIGHJcPgJOOlWTRFGKLMKEKSKNLNNQLKIGOSKMNXLSIRNSGIGGC8C88A2C86A8C862968CCCCC666GIEJDED8A88ECISGM2IdAeLSFCJJCD7BGEEUV6aDl*G-SDRDDHC8CGECDH6GAGACMEHNEVDIMAPNCSECGPEJUEABJa*I8RYRPFRZXOOEGQLOD* * c.95.1.1 Thiolase-related
[  57] AAABAAAA9AAAAAAAA9AAAAAABBBBABAAAA999AAAAAB9998999AAA9AAAAAAAAAABABA BBAAEBBBBBBCBCB8AAA-ABAAABAAAAAABBBBDBCBBCEBACCAAABBBBCBBCBBGCCBDBCCDCAABAAAAABBBBBAAAAAAAAAAAAA958ABAAAB9AAA99999999999999999999999999BAABB999BABA9999A99AAAAAAAA999A99999AA9999A99A9CCCAAAA9BA9EEEEEDEEBFFEFFFCBAA9AFEE999CA9A999999BE999999999A99999A9999B9B999999999999999999999999999899999999A99A999999999A9A9A9999A9AA99999CACACAAAAAAAAAAAABBABBBC9B99BAAB9CCAAAAB999AAAD999C9CBBBBCBBBBCCECCCCCCCCCCCCCCCCCCCCC5CCCCEDCCCED9DAAABBADCAAABCBCCCCECCCCCCCCCCCCCCCCCCCCDCCBBCBCBBBCBCBBB9BBBBBBBBBBCBBCACCCDBBBBABCCCCCCDDEEDBBECEEEEBCDCCBBBCBBBBEBBBBBBBBBBBBBCBCBBCCBBBBBBBBABBBBABCBABDBBCBBBBABBBBBBBBCBBCBDECCABBAAAAAAAAAAAAAAAAAAAAABBBDDBBBBBBBCBBBBBBBBBBBBBBABBBBBA8ABBBBAAAAAADCCCCCBBBBBBBABBB-BBCBBBBBBBBBBBBBBBBCCCBCDEBCBCCCCCCCCCCCCCCCBBBBBBBBABBBBBBBBBBBBAAABAAAAABAAABBCBCAAAAAAAA98AAAAABBBCBBBBBBBBCCCCCBBBCBBBBCCCCAAA9AAAAAABBBDCCCCCEDCECBBBBBBBABBAAAAAAA9999999AAAAAAAAAAAAAAA9-9998A99999999999999AAAAAAAAAA9BBA ILBAJKK-gCCBCCGFGKHGGHJKGJJKKIIKJMKJHHHHHGGHHHJKGIIIKJHGIMGFGHGGGGGGBIHGGGGJH7KIGFFGGGGHHEQDGGFGEEEFFGFJJKAIYKfLTKNOXJKLJLKKSQKcN**S4QNXIKILPINOKJMJIHMHIXLIMJOQg*JOLPJNHMvPQNOJIIJ*JKKGJMVfeIPSJLUMQKN * c.26.1.1 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
[  58] 3321218CGFFGFIGA2A554531G55494A521--------1-311-1-644-11122126432-56 CEN7k64AAAD544NTROO-OW88mwONOOORVeffWf*x7ZGlYGHA7EA6MKPEAF11KKO9qCqmfWD31112421--5M112111122-311----9-7-P3B74--------------2432324422849CCCA111FAE85D3331223---22-213CCEJ71----1------78588651D2FDDEDEDEG4CGECCEEA889ACBC6537DD98888878C4898888889998899A97A41A-8D-9--3GG6678B4565C4453221222555444444445452222222222222433221333337217332433433375111-1-1121-211--2121312423334411494GMDDF11111JEXQV83COHHJH6788778577D-JLJGJOFKDPN1RPPHVTSUVYSWJO8L8DCHHDIIG9K77777777DFH668AC111111111111-------------111147OJB55C79FUUVYWUTKJKIUUPWNOMM8JYMZIbTO-3ABI8F899JCHCLF7BB-433833443343428B764571112-132111-988466534DFIISV583----111111111211111-1---45654DA697NA7576675A577746666576--16643------CE8C4BDIHHKIKKJHI-GIHGJGHGGIGHHIIHIICJNHEF975DDF8EDGEDGD9D98DLB9BDDCF2-988888888888---522122655537BLE2226-3-1221-24177A7E48596L3LNNMCPNKFIJJJFKII311213111-66793332369757BDECFCC9DB6333--25AA5588--------1--------31--1-------21-----24122252326932 -277x*C-NA5158N***t*z******XXQVRUZXQWVTTTSSRRP*xr*****uz*vYYVWKIZAIHDIDHQDOKLGKKENONNNDDCv*e*UlTYSSIVCQSOS-J*V*KRHNLKHEDHGMEPQGaDx*N1XNXHHDFJCERABFBABGECNFPGKTPPH9XLOOGITSDGFQ9LOC*B8BJRch**zhtGI*wqmM * c.2.1.1 Alcohol dehydrogenase-like, C-terminal domain
[  59] ---1---111111111------11A225-442222---4232459412--G63-1--1-1-1------ CEF8*JCEGGJDEA***qr-p*AA**rqrqq*********7*U*uqOIKUNDSbXPAi--hlmA*v****LA7778A94ASgE544327572-333---3E635T4F8B------------------23-1136147668234U2V3BE7811111------23-JBBC1------------D7F4532269JUWVWWTaXHXXSTUVNKOOMLSVY99EQM7ACDDCB9gn387797777777777C46CBB7I5GF5A746NQ55FF9A6DACDFD5664435FIG333335333334544544465454G3433344443J9RaCCBECIG7B57HMM3444J33478664-YTB534A8341233384G36*UVU-----WOyWh749fSSSJ8888877888N-KKPKKcJPAli-nVVUeeTqsoQUPPDZDAPHGBHHDKPCCCCCCCC8FG8A8FJ------------------------------6cnI37SLHTlmsnsgOMLMKWWZcOOOOCP*QwYiid12OMOBEFCCWBSHYJ5G76ABCH82222222336AA97*MY62894BL777-484C99878HGDKVa4A4-111111111-1-------2325834HH8CPBQ9L99FHJIFFIIIHHGHHHJFQH--22734------EJDG8IADDDGDGGGFE-EFDFGFEDGGEGEDFCDDBNRNHGABGDBCDCDDCCCDDDCDDNBDAAADCB-A76888867989--161111122225LVAJ844646233233133hhkmkMJ788F6fgcfNeYaQTQQNEXUU---------3BGENDEDFEHHKIIMUGGHFF99A2-1---57TTAB99--------D-3------------------1---11144522242221722 -------------5------------------------------------------------------------------------------------------------1--------------------------------------------1--21---1---------1-----------1--8-----A---- * a.4.1.9 Tetracyclin repressor-like, N-terminal domain
[  60] 32432677777977885656536534437455646344354458642546A88445555655443123 6DE7B99899979998788-8A55978888879888AAAC5JGL8D8A68A7CBBAA955AACAC8ECDD6756677767CB767555897735441--8E999D777955555556565555587597567796BAABD444E7A99A9996688669777C866ADB6575556676555BBG76756789CCCBCDFEAEEECCDA6998BDFD756D8BB766776DFC88888888888888ABCA8AC7A99AABBABB999A889AA9A9B8797767776555766656668877788777788B786667777596A9555556696989875888D577979G68DB97878A86677687BA5A866755556B8CBE867A9AAA88898888879-87C8BB8BAEA7CBBABADFEGCBCE796BBDBCBBBBE777777779667799A556555555534554555755566545456869799BA58ABBEBDAABBAAABFCCCC9AGGAFFFG59A9A9C898BC8ABA7BEAB99D966555558777887A6765776698555A7AA9EB679999FBA5855555666545755555546595AAB7A56B76595855555665766565655765-5677A44144477897A6A77BACCCBB-7AABACAB9B7CAAAAAA8BBB97C7767666766666766669769997955776777777877455855555787776A7866666766767677768788778ABC8BBDBD9AACBECCA99B6776677778667977777787AA8877868888555566C778676466676666457AGF67-757577655558666755558855585556C96 ED78OJa1*OQFPNPDDJBEDDBBFFGBBADCBDDECBAB97AABAFFLKNJNGBGGGGCDGC9999A6889BB8866898CBCCA98A8GGDECQ98CBBCAHFD7HkP******ynnghnvs**f*k***5***lpgh*fr*gepkne*jd*n**tyduwf*oYM*OZ*UaoaHUkH*BCDEFVQUbETPKKLUJLJ * c.37.1.1 Nucleotide and nucleoside kinases
[  61] 33-5-5E7AFFHADDF47ACD226HA7BAE8E312123432243-1---322221345354B763323 34FDY6-BABE537*ifNN-N*22smLJLLMR****en**7MANH9C35751OIS988--KAM2UEMUaS8-------122398A189----12--3221B345H6972---------------DDBC77DB9799885822255LIIC8893466666355CC58BBDA2534223624323624442-46BCCCCCB5C7D8CBBA94FFA5DDA7A57B875666565BA999797A97999979BBAA833-4312-1-852286-2-1226663335----------31-1-1------1--------34---222542326333231313234761433325323125-DB2344-4462216-3331FH99F-1---GHXIL95665ACJ23432334235-CDAEHEFJ9LG-JEEGGEEEDDINCG4M1FCAEGCEC5DBABBBBBBA66BAD54---1----1-1---------------1--88QE82BB873HBFIIM8JHGFRRJIJLJN7MZMg9NJB-5CA8Lj994GCEDJ723889741321111118A93B63675454756977A-2421296D58A96DF262---2-----21-1111111A3-6C8A65B9H521748143336774446649C699---4D96------66C6-5611131214-1-1111112122132211112AA955AC634122211214212--D211113212-22222212222---3221226676AT6GD211--21-------1QNLTQ8H46A85HHEEDGEJE9BD8BIEC225-22322AB68633333845445455B65779----5541DD--65-----1----31--2---1--2-----3----------2--1-13143-3 5422UGN-O8G1BAR***o*v*z****bYVWQVeaVnnhnajnTSR**n********gcgeeLDbAFE5K58KNTBB5AA9ILKMJAC9n*d*QPUHKLITIOcPT1E*K*XmeVcjMPTVQbQspSkL**Y-kVnRMPSiOTcRNKOUHXJLqPVOXYf**9nN7FSHJcPaYhHVbO*IIIKNS*w*x*VMRJEIQi * c.3.1.5 FAD/NAD-linked reductases, N-terminal and central domains
[  62] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----12D-21-2-----------------------------------------------------------------------------------------------V11**********************r*****************************************o--------------------1-1- * g.3.11.2 Laminin-type module
[  63] 33213253223233232121111262254341--2111----131117747582111--1-3111122 ADd4953477633259966-6A2296666669BCCC7BDD187E232-2---3441-2--5554E468BA734442441-2A3112--2221-122---57545C7855--------------224372423485JJION---O3957745C22111114226542FC9G1211111311115532232233533333224232322122555623344453--------D5211111111111111111112-1-11---------1----11-1-1212-1--1--1----1--1------1-12111-1211-------6563322222222232244334424511413125512151132---3-2271V444311111199GE553A999A22222222224-8AD8A88A5B5573336799897554557E95CACBD4A1111111133414875-------------111--1----------153121354351114112-11122561111115497684--43248121786194--7568832-------2217429H63415525144324351332495464Pg341-1---------11-1-111411577668347433443456775558776677B567---3424------14-1-3-3223332823-2222323232232223222-4412--21-1-1-1--1-21--1-2211112--177667767665---5-----554584C13111-111-----3-411111-4-21344444486654645385611222212155AA5222325779833344453332121111577666644444545731------------------1------181-1-1-1-2444 BD11fcc-H447756656577666654774557798596767785647589CBI57584AAA222232-22232222122222222122DBB5A6G85666474331J************************9****************w***************ZDEBGR***T3IA4a565B5PVRU9TIDBHEGEG * c.62.1.1 Integrin A (or I) domain
[  64] --------1--1-1B--------88--1--21----2-------------f11--M-------2--2- F-gK3WHUDD6c-M3RD86-7e--NNM8OOK-TcRfAJeT-4Gx3-3H-1*LC257C*--D9D12-jDE5-9---KP-1-491-12D423F4-6B-9---3-11CAD1---------------7-1-2Q411--4----12517-l-312-C------------H5B-91------------5A-1----5M4----5739AAD796H-B992-846BG992F-D--2-2719853H-322787428-678F87O4*U3l-E844ICE1B52EA5dxY7A2dIlF-957B3C87776963F62F756AA879288SQFC88-AB7-7112111128-S-FF---T7CU-2B-776B4ZBHC3M5A9KAY-8-93ES88D-----12d5IOr46241558A9887769K-INd72C5F6H2-588HF-QCB9NPBG165J744W9DF61gegffggfLbNW2B11------------------62-----1-1--B6AA--1A*oCFJST8V****ZYJH8HGF5C3*h-35w-4EGfC7Wa9EEO36OB8g12316A35E7B9-UoTe-3-1E143AU65138--915GGCBFC5115F6441-----------1-------33-7-7E-e67e284-2A1*JTHGJ3D8B92tLD966---1483------1115984GSXPLAVNLD-SEH8TB95*EVFHDCHED3P7H4-HA15H312F317AH5712WA*******1-J*prI*h*i2K3--6156-15E444A45-EH99-271134-3-1-5-H3435HCOKD78L44-67-5535IaBEk--------6f-3C89769x3DB9J9bWzQZ***11----M-8588F7--------7-1B9C1----24A----2-DI-5-11-3L1Q-------9-- -2--M14-1---U-V41--L-1---431-31-1-----1----H-3Rb--2-2712-e1---C66--1-Q13--3Ai-C6-24B-31-B*6J11I63--E-UH15*--3-12579J331--12111-917Q535471211423e-33111532312D443U12ECD*21-4C1H1-161---11-QlY9g75*BV***6 * c.55.3.2 Retroviral integrase, catalytic domain
[  65] ---------------------------------------------------------1---------- --1-2-----------------------------------------------------------3-11321--------------------------------------------------------------------------2223--211--211222-111---1-1-----1----1----------------11-11-1-1-------11--------------------------------------------------------------------------------------------------------------------------------------------1---------------164331-----12211---2-12211111111111-11213312311-311122-554---122343-3122232------------1231------------------------------22412111--111-1------11--------11-2223-1111-2---1--------1213-2---------2111112-1--11221141-----2-11-----1-2--------------------11--------3--1-312------1----------1----1-----------------------------------------------------------------------------------------------1---------------------------------------121-21113--1211-121111-11111---------------3132422233------2------------------------------------------------------11- SOKVtt*-*kqISSXEEFFGEEEIGGEBCBCEDEDDCFCCDFIDBBFFDFDCFDDCEEDFFFD8A987799A88779588889A88BAAFGBEBCEDGEDCGCWUU6W************************H*********************************v*v******7*qv*KNIJJ****H**Qf***** * a.39.1.5 Calmodulin-like
[  66] -------------------------------------------------------------------- WTt-------------------------------------------22-2--222-33--33--2--4432------------A87GFjlqd-q58---ApASG*YuGb--------------AA69ACC77DGC333332--1-JOGDHFF4466676FABAG4eDFWB-8-----7-----6333--33524444444444444442322524426325344------G722222222222222222222-----------------------------------------------------------------------D33F-------3-3-3551--------3-29344C66439-3-----81aBQmLLY33333Xj*w*qRn*twlcDGIKDKKDIEP-**ll*ywyEXU-rYYaXYfZaWRYaxJOMB8QFJFFDBCPPPPPPPPLZVOJLVL3322222222--31663563234432-22379MOBLPHIUduyryWYNLLKccquXXXXMZkbnbpp*-GjmiJYWQY*fUKUOThiNhVaQT4444444OHWGVeNDN6ACJDDPLGGB4HNBKKNVKLTVRSeM8YK74447777778A8888888IE69IPYPMEncJnXXREZZcddeZuxgfngYp*qwg--4VNCS------OJJMGbKORTSOSSUOO-KQQOOSSOKQOSOOOOOOOfgdNMADIMIEIMMMMMMIEMEIITKEIGDKK4-RPPPPPPLIPPP--4IBEBBAHSORkOWIH333445344443444OOOQOHR777YOkmmmgbkmbinlaPUbd444444444UCTTRKKKKKMYXQRmsgWkWXORRGDFD44JESSEHPQ22222222-----------------------------3---22222JWL7 -------------2------------------------------------------------------------------------------------------------------------------------------------------------C----9-5-------4-----------1--I-----J---- * d.58.44.1 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
[  67] 555463ACMJJPAKJABHCA7A7BH88BDG964FA557674455G3OGEANRR28H689C8AA94252 AKhGUA6977C665CEG88-8I55CC788879JHGHEEJKGZVaWAMG7HI8KEGKK733KIDANEHJHIE5444532-242IA639AZVXW4aAA1--DNGJBUVREP111111111111116BAFJJ7EGLNButt**455uFuZa*deY8BEEKKDBHGKVFUntwX7BAA985HCD77AB88BCE5A38A8B8C68A778B8778CCC8A77H7A8579D222223BU777878988887788C987525466855459EG66CD4D767576355553334228567568534522222222222229567586666A6-NBEDE9DB96C752669IA995C56F68CACBF8O7B69C638D444D8VEBDK11111JNRPJE69BFAEJ66AA599687F-XSugWndhII91VKKILLOGPFTUOFD969DAHEIK8D7GGGGGGGGZRQOILQV----------1122225323253351-2-7AGR66BKKEMTKLMRVNHIIIIIbhNNNNGNTQhOBFC169D5DEHB659CBC367HHD5AB87634445GELQNK3NKJCIYVFdNRQPFMPPKLHWELTPVUXcOMAEBE9443344151111111CB77CMJ764JLAB2I473353633624323553143--1RFCH------57AA7977889779586-8877888B788586676696A764CC79879898A98BA9ABAA87475659-433333333332--11555552532M8PF9343714-223432147437568666HELIIJDJKCCGFBG9FKJ86877967659AC855455B97BC6AFFGFFCCDAAAA11X3DDBBBB111111116-4--11-----11-----1--------EBCDDCCDB9HgIO 1255AAH-D6427CCAA76ADECGFFC7777878888A88888777A877789B998A8BBB6556554585555783686555559998A7A788889A886BAD1Hg7*CGAB7B9566898KI6G6L*E-FBR6975E79EA68774876G7778B8AC8D866866A97G58LNH*GHFMJZVkn8WHAALKJNM * c.87.1.8 Glycosyl transferases group 1
[  68] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------g----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1233PN9-E5729AESXpI9DBCCEAFFEEIFHDCAJECDEDFDBCgQHHMQOVCFIGIHFHQ45355164452644244466666877e*bXj*h569D778EiM-J************************e*****************************z***m*******Z5pR6U4358I****a*fGJIJJKB * d.42.1.1 BTB/POZ domain
[  69] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 9547TVW-XEG-D9G7BA968888688999B788999A78678677788798A96899A998387789187C986AA48AA47685776BDABDAABA8A58BMIK2cc***********************j********************************pj*id*n***-HGEvBCBF7nfj*AnXG8Qshme * b.7.1.2 Synaptotagmin-like (S variant)
[  70] ------1-----11-1-----11-2-14-112---1--34322-1132-1346-122111-------- --2-1----------12----------------1111------------------1--------1--1----------1--------------1--2-------3--21---------2--------------1-222-2-----11--212-1-1---1-2-1-1353B-------------------1---------1----------1---------1-1---------------------------------1--------------------------------------------1111---11-------------11--1111111-1---11------1------------------------1-2-------------1------1-------------21--1--1-----------------------------------------------------------------------------------111------1-------11----------11---111---------------------------------1--3------1---1121---1-111-226-1--------------------------------------------------------------------------------------------1---1---1-------------1-----------------------------------------------------------------------11111------1-------------------------------------------------------------111-------------------1------------1---1-1------------ JBAIs*w-*WeL**ygaimcgkegodgdfeidhhhfcfceYdeejgabekeaendhebgeghccSYZYAXZTeVXYX6VWUSSZQaprnnwfasjwecelbncy**F*******************v*x***V******z*t*********uz******l**q***m****o***Wahe*nlhcl*qr*k**eei*txb * a.118.1.2 HEAT repeat
[  71] 331-1-4754454653-312111-A44431631-11111111222222135541-1--1-13461--1 8BC6QA58CCF658NSOBD-CR33LfBBBBBHWUaXPX**AQ8c9A893A65XLTEBE--GIY5IGWQPRC22224441133H2222221231322-1127386B4977--------------133333323333888A911194778756646332224435565778522222222222298967123DAABBBBB9CCACBBAA9FEDD8CBCDBIHHG97666665F64666666666666668777742324523212454444131344222444433324433333333333344344444444442244222241455D555655675626663554A53315312277362121114211124B1ALGGB22222E7HCM658BD9BBGHINGEIDIHJ-68E64M7EQTC-PMMNNNZVRbUVGEDD6EKYFCDFBMNFEFFFFFFCFD7587B11111111----1111-1111-11-11119BQfC3ERNFHhcfecgVOOOJedilUTRQDTzZ*QfaN25IEHGCFCAJGPEOW4461223E73655555253EF966627445645335-4445547875555CH26322434322211211111113132254DB4AB5O8GDDCDDDDBDEBBBEC9DEEDH-1-6532------EC8A7A9ECCCECBCFF-CFDFCCCFAECCEEEDEEDMQNCBFG7FDCDDCDDDEBBEBDBMAA5889A417898AA97AAAA--1733122999928EMa444334-11113535POQMM9I8DBK2NNNNPTTXIWWSSDMJL5332243333877D89999CFBAD9ABCBCA77711111122552222--------213----1---1-12-111-13--111112212121314627 --22CCC-E761AD9JMPNUQSMXZWWFFDDDDFFEFGFFFFFEEEHELVWk*wTOJEEEEFEAD7BB5C99EABDA6BA9CBABF688LdFMDHGGEFACDIGDG-9XBgTnTUTUNTNHLNMVVOdS**T-XTjJNQHWMNSHFMKPKKPKfLGGJSNjZDUILEWDHNBNWE6CC6*777BCPKhdNM*A9ZJaON * c.82.1.1 ALDH-like
[  72] -----------------------DZ78G4RKO--B1-122124nf1E*-NOFJ-1-1111------19 7Nm5r5556653-5ABA56-5G228F644644JDFELJNI5XQfaI788FE9AB767822DFK5tDM**vT6333A3356G9835788POQP-M43---5a6JD*LkMX22222221222222-33115-363F2TSTPO553a4PJTcLLBEH77554755CAB7TUgC4464434534638895434249KUUZUYSZcFaXabaaNRMLFPcbi7EEaBHBBABBABq*8CCCCCCCCCBBCCCBBAB695335642326882366544274556DFD99BCBA9788688987877988899899988A775546577FmLQ*SSRVVVVYSSPdTSGPRMrLL8CBOaE6VULA6BAB6AD8EI557LFDKGGI354446CNQXG6AHPEJM8778885777B-SNQNLPPWEN6-FGGKGEKHOKKMKEFA8C6GHMEFAJ73333333339966NEE---11---11ar2233223322222----3BAG869855EQLOPOMNDDDCKKMUGGHG4LOQQLQSP12JNDKIOEFTSURL7LOJFJCHFB1122222586IKQBRU789LA3aHEFD3iRpMTaeARFEOGWW9MM9886777757444444444IG7DG66FE4NHRUCPJ8JGKKIFMHJKJFGIGKHLR--3475B------IFFDCHAEEEHEGHIEE-EGFFEEFEEGEGEDEEEEEMJNFD879HFGEEHGFFGHGHGEGFDCCDDED5-EACACDC9CCCC---C2322254448BV9I444434133433226B9AAA39998BHLLMKKRTMHNRPOHRPO2----11--7HHHHIJJJJJKJJLNNQHOGKFJJ555511G5ZZDFLJ21132333412-------------------------98789898A74V1E -1--22---1-1-151--11---1-1-11--------111-11---3-1--1-11--121231--1-1---1----1--1----1-12113----1332-2--223-17E-----------------1------------------------------4--------------4--2113-11-1U45G-6252F---1 * d.122.1.3 Histidine kinase
[  73] 44444466666666665555655555555555455888888885555555565755555555555455 9AA7F97888788899988-8866A98888888BBBCBBB78898878877689987866899688BCBA878887777888888888A999698864588788A78A85555555555555578888889987A899888889898989986788777777998888897777777777779997777776677777777677777786666677766687777777778A78777777777787677777788777788789988777877777678777777777777898788787677777778767789777A7878BACBCBCBBCBBAB9AAAABBBA9A8999AA8BB9A8979888897879889999AA8888AA9BA99AAAAAB9999999999A299B99A9AAA97AAAA9AAAAABCA98A989A99B98888888888898888ABA88877777666666666666666667777689988AAA8AAAACAAAA9AAAABCAAAA9ABBBCCDA79AAAAA999BAAAAA99A8A999A99A99999A9AAB8BBBBBBA9BAAAA8CDCCCCDCBDCDDCAAC8777777877767666666687767AAAA9A9AA8AA9BABBB9ACBBBABABBABA637AA98776888AA999B9AAAAAAAAAA-AAAAAAAAAAAAAAAAAABBBB9AAAAAAAAAAAAAAAAAAAABAAAAAAA95B9A9AAA9AAAA6679888888888A8B99A9AA9A99997988998779998889ABBBBBAA89BBBBA8887887788788AAACAAAAAABACBAA999999A9999988A78889886666666686755556-556555555556555555566666666667A78 IK68KJH2wRL7HGHFFFDDFFFHGHFFFDFFFFGGFHGGIEFFFFFFFFFFFFEFFFFFFFGFFEFE7FFCFDFGG6DGEGGGFEGHHGMHFGGHEEEEGFEIMR6JWcpMhNRTNGEOHGQHYWEfEt*Q3RWdELLDuEKSMFJHJFPG9XIOGJLIazHJLKEVJHibOMKJOON*OMLJNhU*qEWQLOQQLMI * b.43.3.1 Elongation factors
[  74] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4-------------------------------------------------------1----------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1 ----114---1--12--------------------------------------------------------------------------------------------7T-**********************R*********************************h********-111-----2--2-------1-13 * b.23.1.1 Spermadhesin, CUB domain
[  75] 44223422222222224122111322222222324222222222222233333433333333432234 1121211111121122222-22222122222221221222222211112121211111112212112111211111112222222222222222221122222222212111111111111112222222222222222222223111111111111111111111111111111111111133322221222222222222222222222222222222222222222222222222222222222222222121111111111111111211-2222222222222222222222212222222222222222333222225222222222222222222222222222222222223222222222222222222211111112222221222211111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111422322222222222222222232111111222222222222222222222222-22211111111111111111111111111111111-1111111111111111111111111111-1111111111111111111111111111111--1---1111111111111111111111111111111211111111111111111111111111111111111211111111111111111111111111111111111122222112111111111111111111221111112222222222222221---1--1-----11---11122222222221212 HEDD65d1R545NOSPQONOOOOONOMSSSVKSSSRRRKPMPQLOPPQQQRRRRNSOORQQQQJLIII5JJNJFKGIBHIJJLLKLPOKOZKQPORPPPPPOPZTb6QrD**********z***********9*****zy*****z**yw*yr******k***qm*g*wu****j6KTm*ehgPLVk**O*XBVGOLNJ * d.51.1.1 Eukaryotic type KH-domain (KH-domain type I)
[  76] ------------------------------------------------------111--1-------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- FBHONLV-R674LNTLKOQLOMMLNILMNHKHLKIIHLGKJLMKLJMNLLJJLMJILJLLJKHGGHEG8GCEGGGHHCGIGGGGGGNOOGQIKOScPHMLDGLdhc3i*D**********************W************z**********************q**h**gFmWU*NOIXc****Q**NcZ*syd * g.50.1.2 PHD domain
[  77] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------s*****V*********T***************oq****dd2BL---------------------------------------- * a.212.1.1 KRAB domain (Kruppel-associated box)
[  78] ------1---------------------------------1---1----1121----12--------- --2----------------------------------------------------------1-----1-1----------------------------------11----------2--1111------------1--11-------3---1-----11--------114----------------------------1-11-1--3111------2----1--1--1-----21-1--1-122231-----1----1--------------------11---1--------------------------11-----------1-1--------1-11---------1---112-11--------1------------------------------------------------------------------------------------------------1-------------------1----------------------11-1---------------------------7-----------------------------------------1-1----111--1---31-222-1--------------------------------------------------------------------------------------------------------------------------------------------------------------111----------------------------------------------------3------2--------11111-------1-3--212-------1-------------------------------------------------------- SNJL**r3*ZfE*lsUYZXVVWXWbXWVUVSQPUUTXWcVWWWVVVWXYVacZZVSUWQXaVWbcVPWAUbYWYcce6XeYYSXaWgVYVeQYWWYTSWNOWQzpx4zy*****************x*****P********w*********zv*y****s******k*pz*fo**Dcgc*VbWUU*w**U**QLl***a * a.118.1.1 Armadillo repeat
[  79] 66EJAFGBFFHEFGG9JAHKJIJd82253949hSoedpohcenOWQYZOXsjoRDH9MLKI989F166 6HT6822233211349966-67229966666589BA88CE6655244241111142121177976496963-1111116K**A7CA7ADCLG5P551112543385655--------------2EDFDCHDDHBEBDDBBiSW68898877777664444467755FA9625322225223267687GFD2235555554545555556244-4544356331232333345333333333333333322324------1---1112--1-----111------------------------------1-------------NdXFiMLLNNONINHIbSREBDBVFP87TA9XX**kgXRNdehHGKQC32AP8444833333ACECJA8BGJGHF8888888788A1GCGCEECF9D436888BADA98EFCA447FBCEHDEEBH66666666CAA-4S7F222332222233222232223222222226367527CB8HDBBFAC9BAAABBEHCCCC8ADCHFEJE6BDEBMGAGGDJGNJBGBJJCC89J454444466BWOR4**uaergavhddf3nqnkmejcUUSTW7Ig*CKIDD99AA7B5A4444544HRDLG88MF927372546BEGHF5CWKKIHIKNGIaI4-17KGC332333LFKELH3UVVTUTTSUU-UVTVUSTUTUVUUSUUUUMGIGKG65KURSTUTUUUTTRURTREKNJONOQ3-CBBBBBBABBAA2225333333333D37938999895887864594444433776D4EEDEBAA78A99AD5674343443436699K77777DE7AC7745455445333378JB886655--------A1--------------------------AGACCFFGCD8G84 11123221522A33322333333333333333333322222223331322332323322322333111-31133211-1113333311133223223332233246134264B6653244344445442DX5-77642428233434223432437446289392347445365-4452k42253668H2621352221 * d.58.1.5 Ferredoxin domains from multidomain proteins
[  80] ------------------------52454441111-------12223412212--------111--44 3442522222222323322-22222222222222222275255522222543444243222232333432222222223454423233222414111114336335354111111111111111111111122617777722244DBABAADBBAB9999A798A6EEG96767766767762212211221122222122122111121111112211121221111124311111111111111111111211111111111111111111111121111111111111111111111111111111111111111111123326222222242321543323311341431242322223121112125223666933333687885444444444444444445168557565675276666666876656545334333343344444444444546773333344423222222222222222537835565532333433334422223357222222336343433453633333646424574224222333333333747656454533833333546446543BCAAIA786434344444433333333355433435533754355745555564555546335451-2644322222254333335554544454-55655445455454454444443433575757577775575564554555521533333333333112345433433453747333343333233333544652333344444446674444449872222222224676555555556553333333444333322525455543333333343111113-1121183-1111131111121111212222213 oSPQbXf-***8WbbUTcVRTTSSSOSUTPTQSRSSRTSSOTSSRSWYSRRPTTNRRQQSRTVOPMMNFNNMPOQMMEMMMOOPPPPPPOfXTXSdSPOQNYQdaeBV*R***vzzmbZcaaoZ**Y*d**v3*q*VfZZ*Sj*hYdeYUkeX*clgnhgpkkdiaN*bi*VfoWQyq**x*smk****X**sydiom* * a.2.3.1 Chaperone J-domain
[  81] ----------------------------------------112-------73---------------- -------------------------------------------------------------------111----------62------2231-1-----A4D-1-2-----------------4---------1---------2-21-2-----------------111------------------------------------1----------2-------687361---------------------------------21-------------2--1111---1111111111-3333331313331--------------4---11-1111----1---3-----11--2-4--11--------1---------------1----------------------11111111--------------------------------------------1------------------------------------------1111111----111-------111---------1-4------1-----11---------------2---------1------------------11--------------3--------------111---2-111-11111121111-1311-2----------------------------2------------------------------------------------1--1-1-----11----1---1--11-1------1-1-----------------------3-1-11115145-46441111----------1111-----211-----1111---------151144A6--------A11------1--11--111----1------------------ 11--UPW-PEC296G4351343333323322322222332222332353233333322433414132--111735-2111-652273-2222314244545339A93**U**********************S*******************v******t*m*********Zbq*4KGA*979B8c*q*2*o7GWXPUM * c.10.2.7 Ngr ectodomain-like
[  82] -----------------------Q*EDWCWKa--D-------2**1l*3C*Ua--------------- IXw49--2221---24423-253337222222633356754A8GU22113425692121132M-I5EGDB911111111-8-G64412AA93-411----9192PLPnC11-----1111111-725CB32HLk7YZYaeSFCd6pUj*QQ1AFDD131232DRDFrz*9111111111111b69314728A9BBB9BBBD5C9FECAA688B6EDF8EB83IF444444NK222222222222232222315-232231---211111-111--11132311111--11111111111111111111111121111111114I45G65675672623A66444213311C2-BAGHNE8O1A444263211S7aJCCK23223AGkndG8DfQRaU99998988998-*w*qwl**APG2HNMIWVNVcYSQNH66C7A6LPJL5A622222222A6675*Rk111-1-------------------------88I625764AMCHLMFMBBBAQPMbFFFF6DINUOXOK25OPPyRYIMZMYoEFHFWHHOLWG--1111153Lgq*D*mVKR*rC*uyt*1*g**bvrVsKNXLq*Mr4--1----------------6815555QHAJGKQFIHLRNPRONKHTSRMJOHGKNV--3GMNK------74B93728668888878-4877878777588788886444556635354455555545445A77344561-A45666643666--17121216754H7W5J111----1111--115656643-11AWabcaTbYYRSVVVfLNR1----2---F5989CCCCCHEGJJRPSVTVUHHL554511*2XXDDFD11--1---1-1-------------------------66143413642m15 -1--761-----22B3745122321242212111--132313311111413227--334232---------------------------11171112221-12----8Bp-------1------------------------------------1---6----3-314--51-4--IH-----213--981318E-14- * d.110.3.2 Heme-binding PAS domain
[  83] --------------------------------------------322---2----------------- A14-u-81222D98**ucc-bR99*ybcbabbXVXV****1ebY2----6---66--5--oW52*ivbn*C-------2---------------------Z---*-212-------------------2---------22---*-JQa-hjf--------------oW*7-------2-----------2--*44949J4L84D9MV5--MMXs44h---C4--222222*1-33333333333333-33----3--------1D--------11--------6--E8-------------------------------------2A----R-----w1HH----1-24---2--446--5-----------2-4---------699-*---4T---2222222222--44-44-4-4---4GES22-2-2W-2M-----A----------------8---1-2------------------------------1---------CGGEGg*LWWMAAAG****RsEAAI-G-----S-1E--K111G7--2----J----------C----2-1---66--------------11121*f-----------------------------AH--66----------O--------------------------T2e6226222M2MM822-2242228288288222222228ZC**6222222222222222272222222--6CBCCC6666C6----2524745422Gu-b---------------999I9-7---kQjnWj*z**IOSYS-*g*-------------H29999A--992282222----------------------------------------------------------------O-- --11--4-----66ikh*k********STWfef***zpfpjloOMLqd******kR***OOO32113221211211312331111-DDD871h8R1112242O442-444B-----------------------------------------------6----55------864--1-24313448GLE*KC2365748 * c.43.1.2 NRPS condensation domain (amide synthase)
[  84] ---------------------------------------------------2---------------- ----5-----1----------------------------------------------------------1------------------111--1--O--22---3-1----------------i-------------------9-1-11-------------------21--------------------------------------------------1-----1--------------------------1----------1-----------------1-1---------------1--1--1---11---------------111--1--------1111-12--------------1-----------7----------------------------------------------------------------------------------------------------111DB-2412--1--1-3-------------------------------------------A--1------------------------------------------------11--------32--------------------------------------------1---------------------------------------------------------------------------1------11-111--------------------------11-118676--1-------------------------11------2-2---1-1-2-2---------------------------1-1-----------1----C7--------1----------------------------------------1 8511**g-***GIJY7F96A6A8AE997647576787665667898976BBAE677A798682375461854D69762553GDADV1-1RsHFy*xAB87ZJ9i*N2**********vt*lz****y*****B***l*ue*q***h**wh*eb*p*py*ggWY*w*R*mt*LS*U1n*O*9DCvU****C**jvo*ovo * c.10.1.1 28-residue LRR
[  85] 971121646646665634544231B66A9A99--1111112111213322323-13124446643166 CIZ7E776997554DA9CC-CG55ECCCCCCEC799CABE4D6D74865644BBB7772298E598B9995-2222223445895A89KNIM-DBB2--8NDGCy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jME677CCCIEKIJFMKLHAB9A8A9996888688AAAFCCGHHKGBBCBCDCD88C8976BA999B9A7BA9EEEBH656FWFCCMA888B99CFGF27qHlSePROKIJDKGHJaZEQHx*Y1YPiEHHIOEOOICMHIGLGFMJHIHOADCBKIKBKCDIITXFASJD*7BBLMVSZzJXVOGYORLJ * c.47.1.10 Glutathione peroxidase-like
[  86] -----------------------------------------------------2-----1-------- GC5BF---111---48511-1M33-211111-FAAA8I96EIFg*-------645-----EC3-J5P8963----1----M29CGQBB-------------------1----------------11111111181EHHCC111F5sWYKNN234HH---4--DNA1EEL4------------bCG84982AE4A9A9A79A3AAA999175554AA9698J4PR444444DG11111111111111111111-124117-1-1441113122111----------1--------------------------1---------7EEAP9999999E8G4dAA6676E6A-18JI8ELIIE885CB933572--D5A9BB71111129ZVVB8KaSLXZ4799489789J-bXUWVBTUBW72MTTWZcUcdgJIYIAJC3A2GGDE8B5--------EHH6-kEa11222222111111111111111-11111-A9JC4EFD72LIIJKKH8887GGYcAAAA4ALVWISLV-3SQNjMfMPf16tA8YXbVMeehS-------67HQpw5QVIOOWVIxYRQT2LJMiJSIaVAAAAIB89OBB91222213-1-------dLWYI43jfLnngzXycu*zyzyv*myxvisrmih**--1EfKl------GLKD6P9IIIIIIIHJG-FIHJIDDHHHGHHHIIHHKILHIK--1B7ACBBBBBBABBBCAFDCB86BE3-F56666655666---Z12-2-JKJLGD*Lv---------------A9AAA5A13-OfXWWWcecdmbZZbYZZc-----2---fXffVffeedhjn**SSVWUWTMMQ3333--j3CC86GG1111111191D-11---1---1-----1---1----H95HFAAAAB-1-- ----1------------------------------------------------------------------------------------------1------------4-------------------------------------------------3----7---------C3----------1--B-----B---- * d.58.29.2 GGDEF domain
[  87] -------------------------------------------1----5311-----1---------- -13------------------------------------------------------------------------------------------------1-1---6--------------------------------------1-------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------1-1-------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------1--------------------1-------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- ------------11-----------------------------------------------------------------------------------------------2**********************4************x******m***o**JKUXa*RY*wQwp*OC------------------------ * b.1.1.2 C1 set domains (antibody constant domain-like)
[  88] ----------------------------2--------------------------------------- ------------------------1-11111--------------------------------------------------1------------------1---1---------------------8----1-----------------11--------------------2-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4--------------------1-----------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------1------------1-----------------1-----------------------1-----------------------------1--------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------11-----------------------------------------------1-- ----22P-41----2112-11112-11------11111-11-1----1---------1--------------------------1-------1----------31--1d3**********************B****************************v****PjZpD****-*S-------2121-11------D * d.169.1.1 C-type lectin domain
[  89] 44544367666666775855666989775667657655765556747667897534333337444-23 55C3C547888656FAA88-8D55DK88888AGGGGFKbT3F7A8565555467796B1174C5C4JCBA786668993286933242777637331--37485I6745111111111111112644889555878888822284C88788955774444448744CBB744454444454498865432779999999A979999997577AA99A6657A77888988EB59988899998899888787766489434367844888344767554445333455555554555555555555555555666444666655ACEBBBBCBDBCC59JI64549544574677DA87845B78889533685CE99723333BAEEG757978A888888888769-99B98A8CBHB3GDDBCECFFEGHED988BCG8888EEG888888887B866A472222222232112222222122222222277BN549IEBCHILIKLDFFFDFFJJGGGH6ILDMCFIB68BBE989AAICCEBC9885887CA66555555557A87EF9B78648777825657968B755656C46535423333322222222224333544A89BA6G8BB79BCDC8DD9999ABBB9CC1-465461-11118ABB8BAABBBACBBAA-BAAABAAABABBCAAAAAACDCECAD9989A999998A8A8AAC688888921999ABAA99BBB--2533333688769ACB666669545545445EEDFF9FBBCG8JJIJGGGMFKJHGCGCG64666666478ABDABAA9CDD88BC8989988843333247BB677733333333623----1-1121---111122-1----23534535457654 4433FHB-PB7599BPUPMRLJLhdgTDDFCCDAAA9CCCDCCCCCKIMUXhsmOOHFFFFEGCH7BD6FCFIBLB978AFHHHGI8FAIzOUGYKJHIBDBEMSN2CWJf8D89998897977C9AB7Mp9-CAJ8988778G568978A67B8AC98AHM6JAACF9BJGIL86GEE*CECDCXQfdKSOJFlXi*N * c.1.4.1 FMN-linked oxidoreductases
[  90] 22---------------322122------------------------------------------2-- 6AU-6---------22222-22222222222-22222222266622242222322222--AC226666666-------4444244444ADE92A664--8G4KCCAI8Q888888888988885666666666I6666AA22266EAA8AAA4488444444AA8CEEIC4444444444448CC4422-6666666666666666666666696666666666444444666444444444444444444443434434433444444424444444444466454444444444444444444444444444444444446EAD6AAAAAAA6A6A6EEC8886A644A442222222246226666222O68AEEA2222266B6A6666666644462266246-86A6666666626222256565226664C666666666666666666266626A66666666666--22222222222226666-FA6AA44444------------------------88884444425644644444448444444-------444444A988488C8A8BB88A8A8888CAPPESUK8E477474444444444444444444422CC4G88HC8G4JJJJJCCDJJJGFDFJGFG---8444------7859667AAAAAAAAAA-AAAAAA6AAAAAAAAAAAA888AA55966566666666666666AA6966A4-A66666666666---C44444444444C4B66643-433344443888888C888AE888889886CCCC788844444444487BBFCCCCCBCEBB444444444444444-A266666678877878444-------------------------22262222224G8C IHe*NNE-sIGAIIJIIJIEJIIIMIIJIIIHIIIIIIJIIIIILLHIIIIIIqIJIMJIIIMOONNNNMMNOKOMNFJNNMMMNVIHIIVEIEFFEEEEMEESUS4R*VafgOWUYJJLKKOFcdMkKx*O5UTWEMQNLJKSHGKQLFKKKbIXPLMIadLNLMQWQZpKnTINKVL*QMMOQlXhYJiUTZNQPMP * d.185.1.1 MPP-like
[  91] 6693B3333333333366333333C99C99CC6696666666669696369966888ABBB3333-66 99C99CCCCCCCC9C6CCC-IC99CCCCCCCCCCCCCCCC9FFFC9F9CCCCCCFCC999CCCC999FFF966666669666973355666666663--666666666666666666666666666666C666CCCBBED666C3FFCC9CC66CC999999CCC9CCCC999699999699696BB99C6767777777777777796666667779C93666CCCCCCA6766666666666666666666666666666666666666666333399999996666666666666699999999999996996669996A839C9999999999ACEEC66699C669669C66CFD9A66977BA66699669996666669C996669999CCCCCCCC9CC9-99999AC96C66999999C9999966666999C999966999999996CC6696933----------333333333333333-366C9666999666666666666666666666669C6696666669666669699666969C9656666666699669699699999999996FCICCCFIC9999CC99966666666666666666666669C9996FC9C96969CCECC9C99FC999999993-69669-3-33399996C69CCC99C999-C99C9C9CC9C9CCC9CCC7C999666C9CCCDCCCCCCCCCC99969A69969CCCCCCCCC9C66666666666669996699966966963699699999996996C666699996C99C9999999999999C9CCCFFFFFFCFCF99999999999999669666666655545444549----3-4-33333---63331-33399999696666636 6579969-M937AA7AAAB9DCDCACAAAAA8AAAAAAAA79A9A96777777747767777AAA99A9BCCAAACC9CC8AAA8ADCDAH9AA9A7777AF9A9F79E9IRIJIJJDCEDFFDSSDTCV*G-SCQDIFCLBFJFEFBCFEDCOFPGGJAOrAH9CBG8AQECEAHBB8*A99CGIGQVAMCGEEA98A * c.84.1.1 Phosphoglucomutase, first 3 domains
[  92] 11--11122222224253214233OJKN-A8L---5--466547E-2U-121315-5-54---12--1 24I2G22-111-2131211-121133222221411113--5B59N-2-B11------1--3461M-6KE9611111---21-1-9745----11----------B-1G---------------1--------12-35576---4G96JGAA14322------4564CDLA------------436--11-6IAFFHFIIBJFGDEGHE8DFCIDCFE7B6iACF333533UO--1-------11--------1---32--112222211112-1-1-21-1----1--------------------------2---------CPKf*PPOPTRPOQcK1dcH--2UKV22RBCN5dfIPEAMDD635CB3--BC-PJJE-1--44Akw*42BUgQSi------------dYuYYGSu38-1KLLnedJcggBAh-C-8161CCCB8J---------B983-*Zq-----------1------------------2D633A8658LLMILKrHFHGGFTcLLMMBKJRYFOHI--JIORGeKJV34O83FMK879EgT-------6643OSNOGELBKXKxlWVf3jjncRigINYXLZnK53TC9E-AB9A5C494434444DWBC-11iX1HOFOFBE-TddcbKPJaWXcNRJNbdQ--115CE------ERgg9ID5554543455-5545533535535555553---ab229A886AA9A9886A66A62424444--C6778A979887---1-----1---21dEp---1-----------11111112219IRRPPXgcwUTRTaYnop---------LFichkjjkjPWVtpCDQMTMOCGF1111--rmQQBBGF77665666U5--------12-1------1-------A-BFF667561R-- 53--9C--3--1--B445-4665646366444455434443444445432323222333333355--1-41-44412111-44445--147748544545574GHw-211K4488A431--3248516-9O415-C212-5115322-347-1C3642C33128J--3-1827K5-1-1--111-5--D5-1--41-1- * h.4.5.1 Methyl-accepting chemotaxis protein (MCP) signaling domain
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kGG4EEEABCBBCCCCCCCCC9CCCCCCCEBCBCCCCCACCCCCCCBBCBCCBCECCCCC4ACACCCBE4CECCCCCCDEEEGCBEEJAAAAACBEEK5FTVLGO9BKGB9B8BBCNI6L9Q*G2FIN9ACAH8CF6AC989ABBUAG9CEEV*AGCC9GAGmUFEEEFJJ*KIIFIZOrdAQOKKOKEGD * d.58.11.1 EF-G/eEF-2 domains III and V
[  94] ------------------------11111121------------------------------------ -----111111--1111----1--11-----111111111-1--111-111-11111---111-1122111-----------3--------------------------------------------------------------G8787721144556645451AA9F6444434344544-------------------------------------1-------------------------------------1---------------1----2222---1111111111111111111111111112221112221---------------------------1-------------------------SJKN11111ECUXa89BGDEID7788778888C-HHHHFMLNBNT1KDDEKJLRRKLNFHEJEAEIA6BADFL545555557B9467B711-11111--11111111111111111111DIQG4BDDATKLNONKDCCDCGGUKEEEFAEQGOFKNE27EFIBGGBCJHOBT84A93333F422222224559A34-----------------------4444CQ---------------------------66A85A9AH6E78B99998A98886A79B59E--24433------BCAB5A7ABB9AAAAAA-BAAAA99A8AB9AAAAAABCEDDD454B8ABABBBBBBBBBBADAA999992-745455555555--1622222555546F7A444626122222114CCDCD7B8AAB1JKKJFJHKAFDFFBCCC2222222223688B7777798A89DDFCECC8892222222-441233-----------------------------------------------1-- 2355RWK-N952BCDQSQLMRWQWWRQGHCGDFKMLFFCEEFF99ANKSkUZgWEHGHECBDD694764C59798AA58A7EEEBA9BARlKSSNL9AB7EBGMJM-G*X*khWboeUSMSfcW**O*U**t-zc*TSOOqPRmaPUORMgQHnTVReUm*dMnkbP*nlWx*c*CNLL*FFEKPk***H**JLjbVhh * a.45.1.1 Glutathione S-transferase (GST), C-terminal domain
[  95] 11---1-----------21-----1--1----------------22-2--211-1-1----1------ BLX6ZB9AAAAB8AKHIKK-KO99NSKKKKKFQOOPPSVR7F9CGFCB5CA8CC934F44GJ77OCObZO964664446597A34333A97737444--8IABOLBL7K44444444444444465556655656899FG---BDE9AE8886777466655A968CEHB345333443343BA956534CAIddjdjjhoTndhikgLFLLHIilnCBBHH89B9999AbOA8A9A87667AA86979BA6BCD9EE99ECBEC99FFA7D77D888BBBBAAAAAA88888888888ABBBBBBBBCB9BM88DC9777A6DAHD999AEDBGBCFCEE9CCCG9B87LAC77EEDCAA7E78AAC7365Q64TKKN46666BDPPOBB8FFFFGBBBDBABAABH-EEGEFHDFEHE4HIIFEFEHHHHJBADLQ9CBA89B7AE666666668897898A33111111--33677758865577632324FDFK97997CJLMMOKGGGGFJJHDJJJJ9IRHCEGHF44FEB88A88G88CI7A977656A6444444446667AB897835468744538989779678979IJ7B5443544343534333333344333AABB69A9A9F879BBBAB89AAAABA8CBB81-5364712-222GC98BDBDDDDDCDCDC-CDFDECCDDDCCEBCDCCCHGE8AFE8DDDCDEDDEDDBDACEGAABB9AC64D8999A999999335E56555CFDB88D77756656476645546ECFDEBA7A7AAGFHFCEBFBDCCDBFDF4444444446697D88888997B6KIB9A9A99777773256DDAA9944444444642----2---1--------2-------33433343335B98 2111983-521-1228AD876A8JAGD6634449877556666445649IHIbK879C5646314----1--1-2------11111---382A332---2--31---3TBc2333112211231311134B3-21312-122232221111112113234216G92-----BB9222116222-5A1-B71311C1227 * e.3.1.1 beta-Lactamase/D-ala carboxypeptidase
[  96] -----------------------7hCDK3HBH--7--------DN1BH2DKF8--------111---1 EgV5N2121111115DD55-5R118K555553WMMM9HSN9YLm*531344-GEK-----CBF-RDIqnaG----1--323-A4A435334212--3---8155L8JSA---------------7544518DGG2*****433*G*cs*iiDQMMO323313OZLL***S111211111211yMAA6774556446466983999889794456898553A3CA222222DD4554544444555444454331111112111111111112113111333111112211111111111111111111111111111111134C7583333333535683352222181-A228HBAICD78586444512-K8D8776-----4BOFG622IGFGA12221222227-XWUWOKXN5D2-6888AA6ACDAAA7745243B89A3773333333358765OFG-----------------------------155B4336659844656E133344EO33333398H898A-2885ECD99ADDF62BAD96A9F72222222338HOI8iSK6FOF8VSJJL2iZhOZbdDQcgnex*BR2-------------------3313474LEDHC9HAHE7GJIIICGAKJJGGEBEFJG---8HAG------9BEF5C5AAA9A988AA-AAAAA99A9AA9AAAAAAACDBCB5357777777777777777B86687873-834344433444---922121654698EC9--------------11111113-11BACBACCECEDDBCHFHJI---------57996AAAA9AACHH87JIIIHBDB111111N5WWKMNO--------721---------------------1---B77C97A7664J24 2411332-C35-76D67899798868622222222212221222228B56967A4743255533111112113221111113333322226372415465643446-658FDOFKQMGFEDGFFiZ9JEw*O-QKZCCFBREDXEBGEC9KAAYDHGEI78F2AF77667S24IA-89181-17AF8ADBB589v**y8 * d.110.2.1 GAF domain
[  97] 77B7678888888888B9888885B778998775655577778656746599A478677675666-45 7995CA99999898A99BB-DC44ABBBBBB9CCCCCCCC8CDCCCA9A9B899AA9955CCBAB9DDCC99999A99889AA75877B99C48872119A898889A81------1221111266558656676BBBDC998BBBAA9CBB8988888A78978ACBAB777677777779BABCC88999ABBBBCBDCBECBCDCBAAABACBB99ABABBCBBBBBBEBAAAAAAAAAAAAA8AAAAABCABBBCCCECDDBBBBABACCACCDBBBBBABCAABBBBBBBBBBBABBBBBBBBCBBBBBBBCAAABBABAABFFFFFFFBGBBCAABCCC8C98897987AA9B869988999A8A796796684444488A887667676678888787888177978977AB74A999CC9999AA656568999B9998877777777988774994444444444112-32-412--22-334455865587778AAAAAAB899AAAADAAAA9BBABCCEB66AAA988888A8B867779778888889998778976A6B8C8897998885978878878AACADA887888777777766666666678889888887958698889898889888989989883-798683314448BA89888AA9889A88-98889988989888888888A9889CA888888888888888898878888738AAA9AAAABAA335655665777887B9A9999998AAAA88897777778888C699A9B9999C9C9BAAB76767767657999888888889887778777775555338966556644444434644----4-445344444445744444585688787778A67 3322BA7-K8A499BABCAB9ACCBDDAA9B99BA99989999A89ABAAC9IBA9BCABBBA999AA79CAAB9EDBCDA89999AAA9E8B99A98999A9EAH-AM7JJIIHK778B79979DBG9Y*C-FAM8A98D9AE989AAA986H8CEBA69E8D799C7868DA79CA7*66797GFUKBREA8KEEI8 * c.61.1.1 Phosphoribosyltransferases (PRTases)
[  98] -------------------------------------------------------------------- ------------1----------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------1-----------1-------1-----------111111111111-1------------------------------1-------1--------------------------1------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NKHK**M-*ZYGQOaUONKOOQPNNKONMJOMNKMKJJQOKNNMOOQOMNNLPOJLLIIJKKNHJGJH7EMFJHEKLCIKKDFGCGOMNTjXOXUhWPONPWNfki7b*****t***slupo*p**e*u***5***esmj*p***c*ehb*fj*t*quoY**o**vi*l**c**lCyaW*QNLeV****N**QWkoqpp * d.15.1.1 Ubiquitin-related
[  99] ------2122122221-1--------------------------11----------------2----- 66C6jA7ABBD413GHD88-8G--E*87888CPILIOZ*x4Q6INLG37AABXUbA6E--GCK8UGiouhE311143262C6O-----4442-211----7-11F1B2D--------------------------23393---461111221112211111112112331111111111111E561124-B6HLLNKMKKPCMLMJJNSJLLDLMON8BCKIABKJKKHJPU78878788888888773459H7A4BI44959JJ55FE94D776555666A999477666666766669998999A988995874538888AK7CSJJJIJJJBHDDRBB9DCCKC5736BC22NO495564395548153214LCEA-----54ZPR-1AD65C4LKIKKKLHIJb-8AX8CgAUZq4-*kkbggn*rwutaP673MMeQITbLKU44444444EAA2-62C------------------------------35K91RwoVdlknhkkUNMMHkk**USPQEKoa*ktwi35MMLFIFAClJiIphCH62445F62222222--18A8-BF45477429768173612543323124715111------------------1--111A895BA95G7C7BA99687979B86A8B6B---1212------ILUG7NBMKKKMJIJMN-LMINRHINLMLLNIIMIINRVSNO667OEPMOLPOOOLLOMMMSEFFGHHG9-EBBACBAABBBB---4111111----4FUP334624222221333LMJLJ9F25298RQRRSYUhMXYYY8STT---------1656D66666BEFCCAA77667545------1311------------5------2---1-111-----1111111255333D343123- -------------2------------------------------------------------------------------------------------------------------------------------------------------------5----1------8--1-----------1--9-----5---- * a.4.5.6 GntR-like transcriptional regulators
[ 100] 444723878888888829888888BA99A9ACAA9A9AA9999CB9BB999BAC57477658773-9A 899BB8989998A6ABBBC-BC99BFBBBBBBGDDDAADCBC9CA88A7999D8998977CCCAD9CCECB9AAAAAA5589D67677777A7A77-2246666A6889211111112222224B9ABAAAAC79CCCCC888B979B89998988979A878998ABA78989799B8A98A99AAA859A9888888887888888A98888888A9ABA99AAAAAAA97999A9999999999A9989675977AA777BB99995767879898887777999999999999997777777777777A778987777AB2BB6668777867B9BB777784946A98BCEECC9667CBA9AA37B7989AA955555ABDBB888EBBBB9989999999A1CBDBBACB8C94DDDBBBADCCAAAC796CCAABCDACD99999999A886C99F6666666655--2144123223222555577988877677CBCDCDEBBBBBBBDCCCCBCECB888A66779ADA89BBAAAB9A99B9A97666666677879A8DB9A8BB9ABBBC4777B7889777889B7A866759899984944444446767699A9B798B8878989999899889A8998B86156BA9342335BA98A988887877788-8888877888878788887CFD99BA7AAA8AAAAAAAAAA9AA777888884876777767777665855455A9AA89C987777675787764587777787777A7FEEEABBBACBBA8AAA97788888778789777777899A889A9AA798887777A688AA992222212141211112-111111-111122-1-11143655858887897 561299A-B3429A9ACBCBDDBFFDCAA9AAAAAABB9AAAAAAABBACDEIC99ACABBBB9B99B5B8AABACC8GB9AABAABCCAH9C99FCABA99ABBB2BQ8FC9A7B78897777HB797Fq81989677786774477669757A78797HE4F786A67K66J6BAC8*99ACDKFOTCRKACIEDBA * c.23.16.1 Class I glutamine amidotransferases (GAT)
[ 101] 22222222222222422322322212424343222222333323332313223111111121223111 1134687777868675566-663366666665776766776767755455556865652245559566778555576554433325344444255521159777545653333333333333345525364435655544222558475334344444444435237573445444444444543442239667777787867777786766667795775567444444875566765576665665555576588786666666666555455555455454443555555555555455544554554444455344453646766667669695866677756544575348635315242433313555575544444445A55545454457777777777616585C98654566776665888556765455766585655555555546544965555545554433444444744444455554454445666588988A75555777766665688787A8387657756579776757A654577455555544598B55935235443555333354445477979B44633333333253343344335454566887CD999BAA8BBBC8AAAAACAAABAA9315697B44533489877A88DD9898BB8-F9799ABA8BFAA8889888888886888899898A8AA999A99A7889863977797777799557655455555677H9B66686666666678688A8977797899A99AAACBCBA9BAAA5555555559BDCDAAABADDCDC8877787777887855B25545441111111122533343-223222222233422133355555555452346 CC36KSG-pJE6DCKIMNNFGGFGHEGGGIGGGEDEFEDEDEEEEEHJKIGIIHHGGIGFEFECECCC5ECADBEFD6DDCDEEEEEDDJRGMKIWFDFEAGCKIJ5MkPdMPNORRSKJJIQMyfMhJ**W2eV*FMIMdKPXGGPNIGWHEcPLLKSOUaIevmDSIOQOaYMCRaK*HJHOMfXMeMoMIIKFIGK * c.55.3.5 DnaQ-like 3'-5' exonuclease
[ 102] ---------------------------------------------------1---------------- --2-1-1------------------------------1-------2-----------------1--1--------1--1------------1-1------1-----2---------------------------------------2---------------------------------------1--------------------------------------------------------------------------------------------------111------------------------1---------2---------------------------------------------------3---1-------1-1--------------------1----11-------------------------------------------------------------------------------13-----------------------------4-----1-----------1----------------------------------2-----1--------------------------------------11--------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21----E-1-----1-----------1----------------------1---------------------------------------------------------F-2**********************j**************************e*****sw**u*m*zX-----1-1--1--------11--1 * b.29.1.4 Laminin G-like module
[ 103] 553344566666658665545555744664G4112332222223324222463498B8A98623A123 7Ia4GA688895449AA87-CA44AH88888799999HGI373597956652BA8A7B11B995F8HADE63333444B667D2-411777B19555223A69KG7D99-------1111111232122212223BCCAA111BE4443334223422211232246552111111111111I8B7777587FEFHFHHHHFHIHHIITCEECHHHJBAEIPBACCCCCATDFCCCBCBCCCCCCCCJDDFGD5859B785747866B9454796657666645586677778777777444444444444487798567784H9CCFGEEFDEAEB6XAAECDB9F6A9C7541FC23324I258A946A5R19CFEC2222233LLN546BA9C63445433443D-88H86G6J9F61REEHAAACDFEBF77756EDA8A99EI44444444D884324511-11111--11111111111111111-127BD84BHF9GIIIFJI79BB9FFFCBCBC59LDDHGJJ12CD965F68K8H6JE373112164111111133234434836366246444-7462424536675DE3A375224444531211111113234411855545A4A777655678944439388368-15575321122277LD978DDDADAAABC-CADCDBACBCDBCCCDCCAHJIED5797776767777777767C969888A51666666655666111833344899932AAC554636345444437555452323344CCBC7EAD59EAA6D9C111--21-13677D66666A776677677773542222114922333333343444C-52-4-1-311121-222-11-13111799997A777677B 1111ACA-QD727ACIHUMLKJJSLRLEEDDEDJJHHGEGFGGBCBEEHPTUZWRSPGFECDEDHAEEAD89GAD987A9CCCCEE567IVEHNMGDDEB86BGDJ-AAG*CKABCG98999A9HBAK9d*B1KGH8BB8E6CE789996B86IAEBDFA8D6JB9DM8B69CMC8ED9*555AENJOTNJM85FEKF9 * c.56.5.4 Bacterial dinuclear zinc exopeptidases
[ 104] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------D--------------------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-223----------------------------------------------1-----------------------------1-1--------------------------------------------------------------------- 1--1hdI-849-OM*mYjRWXXXafbfTVRTWVXVUQaVaQZXPSRMSXedUxVJSYWUTUWqEDBEC3C9BD8A8868B9CFFAFABA**kY***GDIHNEK**c1Y***y*x**ohXacj*m**W*k***6***QcXV*dq*uTweiYvdR*dznu*RXQTuq*FbQddF**d4WVWj7BApB****a**DEFMOLB * a.158.1.1 F-box domain
[ 105] -----------------------------------------------1-------------------- ----1-2-1---1----------------------------------------12--9--341-91G384------------1----------1-----------------------------------------1---1---2--------11----------------------------3-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------111-1111111------------11111311-1------1--121--1112---------------------------------------------------------2-------------------------------1----1----------1------------1----------1---H--------------1------------45-----------------------------1-11--2---1--11-----11-------2---------------------------------------------------------------------------------------------------1---------123--------------------------------------------------------1113333332325511----1------------------------------------------------------------------- --------------1--231--13-11-------------------1112131111-----------------------------------------------121--fH**********************-************o******w*********sjv******9G*N-2256111T---4-1--7PNOVX1 * b.47.1.2 Eukaryotic proteases
[ 106] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-1--------------------------------------------------------------------------------------------------------------------------------------------------- DB89YZc-*gV-aZnafgbcddcifigZZYZbZcbXbZaYYYZYaZabbdhgoiaddaYbbadWaSUXPYVWXZZbZUZZYYXYXYQOOa*bfbbfbccYcaczr*-h*t*******pjyonpt**k*k***2*x*hzkk*mp*hequqfreV*qrqooXklXhbYc*ak*djuYVjeh*heeYf*z**f*z*vqolk* * f.42.1.1 Mitochondrial carrier
[ 107] ------------------------44444354------------------------------------ -----111111---111----1--11-----111111111-1--111-111-11111---11--1122111----------14--------------------------------------------------------------G87977211444455344519A9F6333344433433-------------------------------------1-------------------1-----------------1--------------------2222---11111111111111-------------2221112221---------------------------1-------------------------SKLM11111ECVYa89BGDEID7787778788C-HHKHGMLOBNT1LDDDKJLRRLLLFHFJEADIA5BADFL545555557CA467B711-11111--11111111111111111111DIQG4BDDATKLMONKDABBBGGULEDDE9EQGOFKMF27DFIBFGCCJIOCT85A94333E422222224659A44-----------------------4444CU---------------------------66A86ACBJ7G99BBBBB9CAAAA8C9AD7BG--24544------BCCC5A7ABB9AAA9AA-BAAAA99A8AB9AAAAAABCEDDD454B8ABABBBBBBBBBBADAAA99992-745454555555--1622222555548H8B444626122222114EDFEF7C7AAB2KLLKGJIMBGEGGBDDD4444444443799E77777A9B9ADDFCDCC9992222332-771233-----------------------------------------------1-- 2222MSG-H77188EPTOKMMPLTQOQABBA89IJIBC7CBBB676HISkQVdUEFDEDAACB383552748586994786ACC78486SlNTUQL9787B9DKHD-B*W*aUOQcOMMILVRMwsJxM**b-nWtLHGJdGIeTHMEIEXGAXKKHSQitTGcbXMugbQs*UwBJJQ*JHHKNh***D**KJcRSdg * c.47.1.5 Glutathione S-transferase (GST), N-terminal domain
[ 108] --------------1---------9224-442212---4232357211--B54--------------- 8AD5*E68889674**yZZ-Z*66**ZZYZZp********4*M*bVGE9HG7KLLG4Y--UWW7*a****I344433323539313224321-221---1A313O2B84------------------22-1126-476681-2M3L39C671--11------22-A68C1------------9584421157DMNMNNJNNBNNLIHMFCHHDHKLN76BFB44444444WU11-------------223434131971-11166--45311315365-------51--------------------11---2----------B5BD776877925137DC1111611--7--4-HG85337634123-223834qKKL-----PJkPU638UMLPH5555544555H-BDJDGSFH6bS-cOOMWVJcefKNMN5I98EEB7CD9FG999999995EE478CC------------------------------4KJD24OIFPcejdgbKHGHGOOVUJKKKBIsIgRYXU11KIJ9B9BBQBNGSH5F57ABAC711111112349974rEJ62783BD777-273B77678CBCENQ3A2-----------1--------113622BB58KAI6D47AABA96A7C9A9D967877--11633------BEAA7E7CDCDDEEDDD-DEDEFDBCEFCDDDEBDDAJMJB966AB9ABADBBABBAB9BBICC9BBCD6-854666645767---51111111114FK9C2--112-1111-121MMNLOFA45495STQSEUPQKKHJGAPNP---------2788C78798BADAAHOADADC5561-1---32EE6755----------2-------------------------22122232221722 -------------2-----------------------------------1------------------------------------------------------------1-----------------------------------------------21---1---------1-----------1--7-----6---- * a.121.1.1 Tetracyclin repressor-like, C-terminal domain
[ 109] 22111132443542262------2IDE955IA4313223D69524113-3D32-11323213261-26 97T2A4966543559BA44-4D2296656764Z9JEJEYY2FMZ4323522AC2D272229JS2E6GGFA63444FIE5468521211aPwZ2bA43--4L3E974CB342442222442222B232455442633335326AB5RFEF4711146G3H31455-4DEP11411221B2143B8544234653BFEFHFHG9EMH8CD4797367BEB7DO465B23366639DG7A55976BBD7659C75E8666A586579A98775C55429BEB88746345663477D8687B579B869A655565ED664A7968D67EB767A99BF8BFDB43437472426JC7F7OGHB2B54353933464JP4574C42H58JBTNFC7A2898887888588N-RHLIGPGEHd94A77P82TP57DG6N666NBFDEC98DBIIIIIIIIM8995S372222222222Ha223322332222222221DF9B36934PCCGFCAQ6777QOYeHCBBCHEaN8Aib29RKJHJAL7JNPCD9C9CE4475C56234236CAh8G4DP97689BkBAB5692CG7767I75856C7A5B525141162323321222A3446EC4EBEY5B7AAF5KNWOADGOBII7JAAJ8A--59856------HBHD8IABUWMCLHQHB1UC9IHKOAJHUGGCB8CAAGRDQHQSBEF59BE6CGABIBF9GHFD6JLJ9E-FCBA8ED9CF8F--4335435897D55846633482363356A86967ADD36AAB43AOA5B7F9KLEFITNB322225222DC96IAB7IAIC7CED4MBNCG878DBBA--435534442863--1-523-----121-12-------2-1-33211122121112L95 11--I---J------------1----12212-1---1------1---1--------16-------------------------------71--62S2--5-d-14m--3E612--5---------------------------9-----------22-4----3O8---11--E1-7g2422211---H--221E*8F5 * d.163.1.1 Lambda integrase-like, catalytic core
[ 110] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----32------BGK****************************x*w****************p**exzLzdh*v*qsYywm*****LOTdsu*h*****xRP*YyZ-BQ*-----------------------------------------------------------------------------I-*--14----- * g.38.1.1 Zn2/Cys6 DNA-binding domain
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b*8-A6967778667867867755886777GNT7PEM555BLBAKE8EDD*99AHERHKWEJUEALGIGK * c.67.1.3 Cystathionine synthase-like
[ 112] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MJLLxvc-*RP5ZcUMONPPPPPPPPPPPNRPPPPOOPOMJPPOOOKMOPONPOKOOOPPPPMMNFGG7IIJLJMKKCKKIJLLJKQPPIWJOMLNQPPOGJQw*v7cZQ********z*************Q***quvz*q***m**wm*xe******p**t*qjcvgjnbq*nEPQE*GHBGKXYfvPqOGFXmahC * a.69.2.1 Ypt/Rab-GAP domain of gyp1p
[ 113] -------------------------------------------------------------------- JT*9*997776976JJJDF-DJ44IRDCDDDFQLLLWJWUGOGWYY477997JDC44911OOd6lJbx*oI222232221D8G33555gipe1Z771114T8IK*K*C*22222222222222133333433354MGGII223WDbBEAAA99BAA888B99897IADDA59555659555595222553HAFQQQQQINQBOORNOQEJIIGFPMRCCDMJ8B433444qV433343333333333444445224224222133222232232223123323331223333333333311111111111111222222222ERMESFFEIGJEJHFHCKKBAA9MJN44RDDFBXVNCHEAFDBCAFC743T3sUHHM344447ALHJAHBIBCMM5555555555C1HGNDJJEK9N82JEECLIDIKKDEEHACA89BC9EE89755555555555649HB2222222222222212222222222323429AHG49FCBBJJJKMJHGGHFHHMIIIIIBGNHKCFCH34CCEAC9A9N8BEI5BSA887FA43333333P678DE696244433864352665665956WSQTk*4A822212222222222222222422166796C9IGAFA7AAAAAABB999A99BDABG2-2866A22222274765786556655565-5765646466567566555555CC79655555555555555556536435643765666565665224C33333555534B7A4444434444444444343347222KDNPLOOWSVENbMJAEEE2222222225699977777B9977KMCDDDDBAB33332276BCCDCD2222222264488F21-111112111111111111152645444447k67 1------11----2----------------------------------------------------------------------------------------------3-------------------------------------------------3----1------2---14342K12244969G-64898---6 * a.177.1.1 Sigma2 domain of RNA polymerase sigma factors
[ 114] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 9ABAaVL-fFE2FEOCADDDBBBBDABA9AA7AA9A8BBBACCBBBD9FGIIGM7DGC9CBEABBCAA28999ADCD7CC8ACDADFGHBKFADECA9DB877RUW-lXa**********t*****s*****M***z**x*****j***m*rm******g**crhoP*SS*W*vX4JF9rCB98B****D*hC8cqgjS * b.7.1.1 PLC-like (P variant)
[ 115] -----------------------1-------------------------------------------- 5C9-821222212235489-9522D599999745552443253832233---212241--5351A1677411111111131122-2123342-111----22114221-11111111111111-11-21111171ECC9B---91NKEICC744EE8264857D5DGHS9-6121--5-1--44355111-------------------111-------1----9BBAA5-----------------------11----------11----1-1--------------------------------------11----111-11-11111111121121331---211111114368--44-111---1--1133533C-----39QII773BCB9866665666647-LPMLFRGO6A4-7886GF7BN98876222C958777C482222222252211R98------------------------------47A7-34424B9989A5757699EF9999488AFCGJB22AB5CC8ABFCGBF553E2365631111111211A7BCNB5B43319644--222242-2268F7LJ272-------------------1141144341456424453322223322244336444---2A39------31112212222322232-2222221222222112212232331212323122112232332222111221-222222222222---1-1-1256661995611111111111121111111111--3756565686953547544---------325565444446555332233311-------E9QQBBCC--------832-------------------------33133-1---121- 7C8AA9E-*VM4QNa888688888A8888698888778898887887888A88B8786878788688756528886635667785565468686666565666EEI4H*A*******fVaaalf*ve*c***4*n*XdZW*UiraXieXTpWV*czdeofo*xr*WW*ab*Xnub2dmh*JQHFINQMe7ZHHj***** * b.82.3.2 cAMP-binding domain
[ 116] --561388888888881766666775556566568668777666666669A88647455-54542-66 87A6G878777877BBBAA-AB55BCAAAAA8CBBBABMH5E8977656776A7988866D9A6FDFCEA96777766337597878788883A33122566786576611111111111111155466544485888CB434968788665557766667686667787666666666666756554457BB7777798777877789BAABB8779B9AB89666666D7877777777777777988897646779A484CB7777678774666666545567767767666666555555565555566655566656A3663336653546A7885555436326436599588547544436135656B99A555568ACA9775AAB9B8888888888A-88A88A978DA5DAACBCCBAC999B87888B888899A87888888978677995555555555--111111111111155555998749DAAC9BBCBAA8999888DAAAC789BCDGHE68997BBA89ECCCFG78A898A985655665778A9A5856488767966747777B6896BB8BAA6775466555565464444444576646677869696766887778877777876878752369A822222277AA7676665666666-6666666666666666665697887D76666666666666666A6666666666777777777773357555559A9979B98565848533336556AAAAA89878A8CCDC9CBCD99999EEB678798867766657777769776779A8AA88855555654AAAAAA--------3-1-------------------------21311434545758 341177B-H75-88CCBCCDDFCFCFEAAAABAGCDDCACCCDBBBAC9DCDFCBDBB9AAAB9999989A8B99BB3CB989999888CFABBAD9AA9A97GHD-BZ8dBE9FFH9BAABBCIJBKAn*I1KAK7DCABBBD87BB9DGC9GBGB9IANS8GC76L87YMCS8A9A7*778CCE5FJB8BGKJIBDK * d.142.1.2 BC ATP-binding domain-like
[ 117] 33213223666656632A55515-E66F4HF4441---3-11335-13-1855-11111126443-32 6DR4Z22678826139933-34223E32232248785CBB8H9RNJF45IG2HKK54D1198A5O4PNQJ67577686-1456112219953-5-----17174L2736--------------1121111--12212275111D1877A5673433343433453AC7N83332333232239E411641A3899999A68468878875556886824647777888869O266666666666666644483AG37835545BB99AA3695CA565333211114422222222222111-11111111122211122253314833344352336211----8-32-33322333121342223152124-6D665-----C9BC91-36644411111111119-78A79F7ACM2-QJJCKKKVQKGKA75726674345854333333337A963235-----------------------------14663648869EDECEFB5454BAHF555636GAM5767--5447352253679224213112-----------1331221-2---33--1-5232125418CBABP-31-3--------341-1--1121-11243394341-8242222323132222112112--2-123------876A2B89BBC9CCCAA-A89ACB99C9BCF98999AEFE871227598A8988998889AA78987883-A87888778888-----1-1-1232136951-18-6-------1-4434435122F388685899788896978211-12--1112222222222222659ABAA8884111--27332333111-1-----4----1------1------5------22721656663B81 23--859-E63245BUNQRaUXQgeieFEDEEDFEBHFFFFFFBCCbRSkWfuhaXNKHIIIHAE59GBBBFK7HBG9KECFFFCC9AEs*hNMyOJJLNDCFRJJ15*K*WWGKFRHDCKWFOXbElF**O1dKcGFFBFEAdQ9AEDAPFFIEGFCNDE88LLFRHFKaSHD74IIH*ABAINUWliMQcKRlOUWx * c.1.7.1 Aldo-keto reductases (NADP)
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g*L-TGXB88AF8FQG9CC89GABHAODAFGPhCJAC9LBFKGDFBCGEB*AA9EELGQXAREFGIGEGE * b.84.1.1 Biotinyl/lipoyl-carrier proteins and domains
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o*I3IFJAC8BH7DGB6C9A8F8BHCCACEERcCIFFAGCFOGJCCCACC*CDCBAEFKMAFGHFHCFCH * a.27.1.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
[ 120] -------------------------------------------------------------------- qk*--------------------------------------------------------------------------------15634****-*FG1--b*UjY*K*a*---------------362754345SB----------C11311-22--------94-cAR2---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------51o2-***z11111L8FAFEOBPB8IA33233333338-NI9IHENK519-788633544359E5sjS41R548811-SOSSSSSS6SPZ83dF------------------------------Z**eNAJEFCEKNMNFC8887EE84AAAA4ARAEEBHH13A9F8JGBCd457K69V58RCRC49G99B9AXCA8MH49D1121241322--32483468G6455KN33L4L6-3322416476664569C163FFCA3q6sjX*h1UabgeNXLcaaUNSRgWOh---A8B5------N8973D79DEJAIGF98-C9A8DBF8BCCGE989987DDIKLACF8866888888768668G89B557A2-CBCBCDBBBBCB111F---------6DD9HD783B435C54488CMKMRJ8S14AXsZbUbVjRdHUmUNDPLJ---------5587779989ECB98*******n*sAAAA--428866CE----------------------------------------------Kt2W -------------------------------------------------------------------------------------------------------------------------------1------------------------------D----1-1-------A-------------1L-----w---- * f.4.3.3 Ligand-gated protein channel
[ 121] 11--13-13333313112--1------21-11---1--------1111----1-11111111------ KS*9*997777986JJJDF-DJ44HQCDDDCEPLLMWMWVFNFVZY487996JCC42911MMZ6iGbz*rG22223222195G33555ZaeP1O551113I6CG*EfCg22222222222222165443555365MEEJI225SFYCFAAA989AA876B98897PCGE959555559555596222433B8COOOOOHIOAMLNIKNDGIHDCJJMCBDJG79733446kP222323222222222322438113244221211112213312142312212331111111111111111111112241112111111111ARHCKFFFHGGEHGBFEHHA786GCE54R9CE9RPKCJD9CBAA7E9523V3gXHHM455559BIFH9GAIADLK5554555555D1HHOCKLFJAN82GCCCIGCGIHEFFJBD99ADC9DD9A777777777655649HC22222222222222222222222222222289IF49FCBBJJJKMJGGGHFIIMIIIIIBGNHKCFCH24DBDAC9AAO9BGH6ATA887FA53333333R677DE586264344843342666956A57SQQSr*5C722212322222222222222422166686C8IE9E977999998A777888AA8AE212866922222274765776555655565-5765746466567566555445CC79655555555555555556536435643765666565665224C33333555534B7A4444435444444444343347222KCNPLOOWPVEOcNKAEDE2222222224699866666CB777KMCDEDCAAB333322B6AA78782222222264241D22-112111211112121111142634444445k65 -------1------------------------------------------------------------------------------------------------1---6-------------------------------------------------313--1------1----4142G12264958E-6489A---6 * a.4.13.2 Sigma4 domain
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buZXebKKKHOSOmaJhO**V1cVl9MKMfNQQPHRNHGQGEVQTRQSIKVFFGEAEBIHDIHEKTQZ*WWRMLZhvx7ZbUVNMHI* * d.26.1.1 FKBP immunophilin/proline isomerase
[ 123] 33-1--6998A99B87-232321B84442349-----------------------------2551-11 3769K638224766SueNN-Na99esPNPPPZjioiSf**3c9g3236233387887911CDR2HGQJBHB--------151D1----1111-1211--2544485444--------------11111121112177766---59411411111111111111111223111111111111166555---9587777766868686665A77578866CBA753111111A1122222222222222211121-1----1-----11---1-11111111121111111111111111111111111111111111111112--1351111111212-2221221-212-4-12-671527-16---1--2-7-1IFFP-11-183cPT646VKWPL788A7786888-55A56M6CDHW-A66587BCADDBCGAKBBFG7ABBAEN11111111A33-1JE7-------------1---21--1--1----2GMfG-9tfPcHLNLXIDDEEDHHPOIIIHAIRJwYrxf34IIEIFDFFOIRQWf54C11--98-------111PGE5bDI1----1----18982H14-16656GF53--------------------1--12--8819C3E5BA5888887AE8888A8D98BB---3411------44852447556765688-587865576756566766755533454454444444444444484545555--555555555555---4443435555-9D45222111111112111FGEDF7E8A9A1HHGGAGDEACBDBA778111111111-343B3333369566889999999A1111--11887777-----------------------------------------------115 33--EB9-RD9-76BIGB8FBDDJ9KHDDDEDEA98BFBCECCEEECDCIHGNLFC8988889342221223333333233444541119I8G898666578CFCF-CmEhNKEIGCFIDCDGGUIFOC**P-bFTBFEFHCDIEDECD7DDFJEEGBOIPLBSFF9I9DODGIG5665l667A9KJLa9HEBDG9A9O * c.14.1.3 Crotonase-like
[ 124] 95-1--ADDDGDDECB-253643HA6661-7C-----------------------------6771-11 4667g3-6222846l**aa-a*33**aaaaar****v***4*E*3443146198A878--TTf1OKaWMXJ--------384C-------11-122---1445564555--------------------------787AA---C932-3113----------1--1225-------------8998A--1G645555537566556555666665658ECAC-1------5412222221222222221112--1--------22--------------------------------------------------------111316444444444424332221-6-316-13-B914B6-19---11-3171-SJJZ1111172gQc555SETRJ77676774647-AADABIAJC8c-NBBH985CAC78DM7UA8CD7666B7G5355555591111794------------------------------NVlS18VIDUGJMUZHGHMMGFFRCQQQQCMeFlg**o26GHBC6IFFTHLKVe-38-1-3451111111212G683hCM-----------765-A-5--7787AG77----1-------1--------1-----54-6A576DE15544456F444484F6477---22--------32841213334344334-343433342333444344545511462665356655464644622324223--133343323343---5223227777-IB22--------------1LMMKMEM576G2QQQSEPELGGIEDCCAB111111111211142222246245557556E455------12BB98BB----------1-------------------------1--11-1----1-4 ----568-732-AA9FDEBFABBD9BDCD9B9A888AA9A9AABCCB9789BEIAC8989884-111--1--1-1------11111---7C7D8877666999CDC-B85GETCCEE7A899D9IB6H8S*D-EBQ7988B9AHB5AC97D86GBBBCQBGI8FCD698EDEKFG2355k44354767EC3665G9A9C * a.29.3.1 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
[ 125] ----112-3836IHQ9-1-----8511-411-2---------------11k8D--B-----211---1 C-S15JI6682L-C26A44-4E--DI43444-BLFL66ZI-2Co336D11*M1348C1--C6412-dGF6-6---CE-2-4B7-12D423-4-6B-R---1---6-3G---------------3---4Z2528-6--12D-4-C-qJDH8C*G211------1TF7LIP*------------24154---4H1-1-115-33292441-6JJ312-18CA1-C-311211811121C-----221-1-2-24--53UO1L2272787C1541--1IcR544D43B-22883984B1699-G1-A11133351-34AIK444-6B--7----21--B-Y------23-L-1C-32512W8A42P398I2Z1--131G33------5-P4Ch*214--41-11111211F-88d2-T43-7--7437E1b7A8OT61-4-C1-5C5-21197A99AA95oYQ-48----------12X------32V----1-54-2267---9*977APCAR1111SREK4211-31IN-237--14J55kR27O815K73Q---1-3--E6961QX9E-2-26-19-H11-23--9-245-BF21-239E55-----------------------4-44-p76F-11--E2N262D9832262F38563---H442------2-9555429BB36J6BF-34325H71QBE79AA1991F4A2-Ao21A-111-1-11322127685KDHO--4ujiA*fvU2B---P------7435-2E--H78-16-112---2-----1135A5R-21213-1611422FT4Ajkw-c-qvk-U-2g8A869*357F85K2111cag------H--1-1---11-----4------------4------7--2----2E1h1------6-1 ----19-----422115--I1---171232323232111124622211212-----1A51E112----------1------11122---3--5-1C--28-a42**--3-9*LGNVG8A89899TK6M8v*P-VGT79A7C999849877965J8H66J57GA99RYLC2aLCA4--622142-----54----6KIe1 * a.4.1.5 Paired domain
[ 126] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2----------------------------------1-------1122--------------1----------------------------------------------------------------------2---------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4322LUw-A35273B5566877657466687667757777677647786797886776788855545425655454545565555554445155594343245CAD1VWT**********x***********a************t***y**n******c**nsvpT*glxTpuU1CA8L45373EC9G7FC23CGGED * a.60.1.2 SAM (sterile alpha motif) domain
[ 127] --2-1--2444444452422221-4--5335---------------41--32---3-443-311---- GHJ2S5A888867-59A99-9C11A9888888ACCC67BC8C9BIFH5ECC7FHJ97B--24A7L29QOE8JGHHEGD5--3921---HHRH4C55---7J168G5KCA33333333333333456566655666GIHBB---G58HL5CD5653356766666287AD7444444444444GEB45232394A9A9A9997A9AAA96AAA3BBAA67716FF5887862J722222222222222111324B2-6922538CC6669262GE6976777B989ADD899AAAA98986444466665444BBA66299969414C3333333F3C46442CBA9-2B4-7I2333133-D4-4342923722B7661-----17AA87769B99A------------BBF9BDACB49-777EHE7GGE8971924453BCBB63-44444444655-83DB------------------------------54-3--8658BBB3ABD69A9AAAF9899859A9888---8888-7---4-9D---867271--------1379913334-744143222-A79366428ABBBDD57-----------------------1133DCAC5J6-G5C8989A5A-888386193-4---9223------8E355868BB9998899-7A89988A98788688777CCA7544-A96A9AAAAA8AAAA8A66577871-777777776777---------33335-C28333686-33223333----------CM8898898AB9999E8884333334334588C676769CBDE93HHJIIBBB------52551122111111-14-A-11-1--11-4--11151--51---89D66858998L8A --4599M----3229HGDGHMPMLMLK7777874446686576988HFEHBFFIIFGDCBBB2452564322717D95OF244447BDDCECG9E9FACB5L7447-8S4X9MBGFC8ABAB79DG7G5qzM-G9H6898A57A778A86974997788APVBOIGNOLVS77B7BKGM*FGGYPXem*CbX-141217 * c.1.8.1 Amylase, catalytic domain
[ 128] -------1---------------------1---1---------------------------------- ----------------------------------------------------------------------------------------------------------------------------------1-------1----------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------1----------------------------------1--------------------------------------------------------------------1111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 44-4CC3-71-------------------------------------------------------------------------------------------------33G**********s***********2***i*******nU***m*oS**vn**R***r*sT**z*v**j-217h1RQ2E3128-5S-2-B55B * b.1.18.10 Filamin repeat (rod domain)
[ 129] -------------------------------------------------------------------- RLZ-3-----------------------------------22221---------------3-----------------1-11-65677MNQH-P67---6M9DCWCO8F--------------697AAA699A99ABBGF---21IFBHABC6566322447AA6NEMX5152311151321-41443351-----------------1----1----------------L3---------------------------------11-1-----------------------------------------------------9A42G111111121312AA2--1-11--2-2B299C996444B1125131I8TWAAG55557PRideO9MbXOOJACDFAFDDDDN-QZOOUYWaCLG-SKKLQQKSOQLMKX7FDC5HBADCC6BFFFFFFFFDOOE9EMI1111111111--22232332122221-1136CLB9BB95EVXYWYQNHGIHRRPVLLLLBNWPTHTPd-4GIOCAAFHTJDFD7FKICFEDGG4444444DCIDFK2BH657FB6EH88B1EFAIEKHDIIJCJFHBHA32233333332422222226524AGGIGFHNDNDKD9KLNNLGLUSMMJPKSUMTO2-2GB5E------HIIK9JCIJJIIJJJII-JJIIJJJIJJJKHIIIIIGQYQEKDEECDBABCCCCDBACAABLGDACCEH4-HCCEGFFBCFGF--2788678FGGHJELCF555344233331113LNNPLEHBCBCCWXYZVYZSHUSVQGJJO764636536DEMMOAAAAAJPLONRUJGKGGDEE545411M1664444-------121----------------------------11-11111CK95 --------------------------------------------------------------------------------------------------------------2-----------------------------------------------121--3-1-------3--------------D-----E---- * f.46.1.1 HlyD-like secretion proteins
[ 130] 4445559789A898CB94856354866999B97967854B8656685665889467A47564445274 63538A9777795933434-361145333332666674665B6AB5A46772697657--B875BBACCC855553331-331312431--4-2112--2734546343-111111-------3-33234223233444911-5455B845623114545454123C8543421233441124743331-464555554854556635844454555855754311112147444545555544455354541335434445344225536221121233234233444333333424343223433333332222212223262231111311313124421123333-5137499B55515142114-336365566----1645568666665824142243134-8666B967553143355665645566443555737863377777777677474891111122211----------------1-2157873223223224446333344663343243574523-122166784553627146252242332233322254135933556453444-6652455467467BC5331112------1-11112111-113336754647375955675669B87857778771-33346------57784558885875787-7777766767758568668767657856546545565567654575466763-6555555455551-111111141117594A444232321222313222-1-11-16569855678A4745G838111111111465496746787B795587777777233332E12211221222122221232231---1---2----111--11152253211121423 SKAFOGY3*SMIEEL9DDGGGJFDEFDDCDECCFGGDCECGAEAC9EEBFFFIEGDDHDA9BEABACD3EDAA9B8U498BCDEBEFDDBTGDOQeEBHDD*GDEBDFpOoIPIKIYOPQMLFLQOKQQk*J3QOcOWQIHNHKKNJQQIMILSSJQILNZUIIHjRGIIfGLWLFHPY*QXMMOSOMZENgPJMKLGa * c.37.1.14 RNA helicase
[ 131] --341366666666661544444465556456555557555554444445444425223-3444--55 6686E867777877BAA99-9B55AC999998BBBB9BGG5B8776656776A798876688859AC89786777666336697868788983733122566776566611111111111111155466544475888A94348665575555566666666665666656666666666665565544469A77777877777777799999A7779997989666666A7777777777777777877777645777B484CA88776797846665555455555555555555555555555555555555555555567356333555453577885344435326446588587545544436134656B99A5555589A89775A9B9A88888888889-7777787689A5CAACBAABAC888887888A888889A76777777866667995555555555--111111111111155555898748B99988899898888888899996899ABEDB6688787978C9AABD668777886555555566698A5836468656766647777B6876BB8B99667546555555545444444457554667786966676688778677778788667775234578222222678A6676665666666-66666666666666666656768877766666666666666667666666666666666666666335755555777769966444646533335446AAAAA8776787BBBB8BABC88889BAA666666666766656666667666778777777755555554888877--------311-------------------------2-311434445755 331177A-D54-88B9ACBCBBACBCCBBBBBB999AA9AA89BCBA99CBBEB8CA99998B9999987A8A99BB3BB989998888AEAAA9C9AA9A97GHD-BF6IBEAFHF99899A9JG9K7h*H-IDH7A8AA6AD78A97AFA6DAEB8F9KR7E966L87YKAM79787*777A9D4CGA8DCDFCABD * c.30.1.1 BC N-terminal domain-like
[ 132] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------------------- ------F-----A9CCBCCC9A9C9AA8867688857A886887769999GFCl7CABCEEE98989857978A778588879977434BG8BABL989948Chcr-X--*********un*****m*****5***h*so*m***d*vsh*qc******dom***oc*lz*Os*R2832314126****B*s555767- * a.38.1.1 HLH, helix-loop-helix DNA-binding domain
[ 133] ----------------------------------------------------------------1--- -------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1-------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------1-------------------- 1-----2-22211111----------211---------------------1-----1---1---1--1-------1--1---------1------1-----11--1-5-2**********************4************y**********w**DJLM3D524445Pa2--1--9----1112--1----322- * h.1.20.1 Intermediate filament protein, coiled coil region
[ 134] 775375556666666658545554A77A79984332222222376356455542795355A8567-56 A7C5C556665555A6688-8955998788879AAADBBC6C867663556599885622DAC5F9IDBE644445442334854544555526--1334858765678-12-111-21----1555556566558889944488857855865575555566667BCB5555555555555A54445544779999999969999AA9677779988AA6633444444B94777777777777765555743-3443422-442234132143545222222254444444444444111111111111153455533325C8476666776766578843337563245585986B6559766554354A568778-22-255C9C5668988A46554554459176966B7B7G61A7779CF9BBA8898889A66877B8C5555555595555768----------111122111111111----466A656BB67CBBACC9ACCB998EDDDE8CCDA8EA84577957ECCBAD9CA4485655974444444456757478486567865541666676985AABB9F6776656555554353333333755564498576794A566877786B666666A76881115666321223B8C87A89A999A9999-99999899A999989A888BBBA9DB8A9AAA9AAAAA9A9AAD98888897-C99989999999442522212444455D89555544144434454B9BAA8768556CCCCCBDC9CBCA9CBB644345544667778888888866777777778866663464776655--------2-1--------1--------1-------35665646864855 --1167C-8421669BBB9FEGFLIKEDD8888DDD9DCCDCC9AB88CFGJOKCEDA9B9A999787786688877788888888557AG8B797988658AA9B-Bs7Z7D99585244855IB3A6Jj6-9693666A867656554753D8A85ADGD5MC5A4345CHN79CDB*BBBGDIISWBQICDKHGFH * c.79.1.1 Tryptophan synthase beta subunit-like PLP-dependent enzymes
[ 135] -----1----------212-2111---1-----1-1-------1--------1-------1---2--- 1--------------------------------------------------------------------------------1-----------------------1------------1----2--1------------------1-211111-----------111111---------------1--------------2---------------1----1-----------111--1-1111111----------------------------1------232--------------------1-1---1---111---11-----------1-------1111-----1---11------1---------------------------------------------1221-1-1--1--------------1---1--12-1--1-----------11-------------------------------1-1----------------------1-----------------1---11--------1----------------1--------1-----11-----------1-2121----------------1-------------------------1----------1--------1--1-----------1-------------------------------1-1----------------------------------------------------------------111-1-11-111------1--------------------------------------------11------------------------------------4------1----------------2-----1----1-- 5133GEG-bA8DA-L44747744727B6658986869A9A6BA666432374248B49662386212--11253141-215353325545134A9112431266312H13****************v*****b************i*****wl******n**HBCIJ*Pj*elK21CF26231774226687-5-6884 * h.1.26.1 Myosin rod fragments
[ 136] ------------111-----------------1--221---121------142--1-----2-1---- 169-3----------1111-1---1-111111----1--1-4132-1---1-------------1-26391-111---111A--621278571324*--A3442A1411-------2332222H4242142265-233-4---5-A262435-1---1----2114316B-1-----3---1--1211171---------1-1-----11--1--11---511------121--------------------3-11--11---11-----1---1-11------------------11-----------------111------13222211224222533-221411--1133-6131-2-21------5a-25234312212586FA8757544633333333334-999967794991A555567496975659E222333312-5555555555B63962---1-111-----122--1-----1-----4232M-----A78A67222224412333323C7B12162-5354123274155212724154-14588857368653C254-434A7543-A6412572376542F367CA23211123A9CDDBBEC82367776426-6B47485A7996757879G8868AA--15725------1-14-2-666A646263-479762582752646644921246125B1D7B1CBCDB9B97B243365852--22222222222---69D889KIKL42736---181-5168243454A5635453619B7A88A88887557773343444332656676777658655523433-------34X95566982312122251---------------------------4212-----64D3 8866QRM-QBA4RMlEGCDLHDEHEJFHHCGEHHIFCJGGBHHFGGEGEHHILSEGBHDBABCB9BA9CA8H9BAC97ABABBBBCGEFAKJGSCv989C4BA***7Zo**KHJIHQFEFGLKLYTIWFm*P9WPeIECIUDOLCHLJELSIFULKJGOHOAIONF8EAFVBHi*89A*z77A78b*t*D**FJJQQK* * a.118.18.1 HCP-like
[ 137] 443212322222322211---112824845651131-1-222-2123523884-33323322241112 2472P214553427LIE89-8I22IH88888BILNNHCGM3S9RIaF6366466674711ADC5N8JPOQ64444555111-3112221131-312---1123446361---------------222223232246AA65111D4966555544222244436644778422422323222277823--2346HGHFHEIM7FCHHHC895567IGG69747641-1111DH33222222233322422442312-22-211232113312--113441111222211111311111121111111121111322222222122265555565755421443553B362-22242443--323222131-41226B7791111166ABB4336676755555455658-77766A895BA19665889C9A8C6928394266665573333333343333476--------1113-111-12----1----1286B9575556777878A4444886643442596748A7234433546573574656B76386422222225599A456344352-54222-4534435835555AF3411-------2----------23-1333346574323436333356444336354355--13995------66753366555655576-5566885556567557557986673325555575575575557544555573-433343344444---4243237D7948885211343--111-2227666957564A3FGIGCEFBDFGFCEEBG1--------654553336355344996696656633333-43776677--------1--------11------------1-----1----1---1-32 2123685-8221224FdcECJOdjXdpttw********r*y**GFIINGNVMsvJXLce88843U123334254433454444334324RyRdMPc45592633342AWGb8EA8995764487EC785JyB-ABF3A76856873A9579A467CCA88AC5B9CBiMeCNPC93VDB*8AG7AS9BHJAOCF8866Q * d.144.1.6 APH phosphotransferases
[ 138] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----GF*-----1111111111111111111-111111111111111111111111111111111111-11111111-11111111111111121111111-11111a-4u*********************5*******************w******t***fVLa*hh*o*TT---1---1-232441522135341 * d.93.1.1 SH2 domain
[ 139] 44121354455556761467864397785568332223222233433444656233233226663155 57A6A45877845485566-67446966666577777EPQ5989576943359AB55633B8C77ADC8A7333333345468334435655354452159787547693333333333333345535533445477799223967876997666665655577569887454444465445BCA7733397C9999988878789888DAAAA8898997865777777785555655655555555555652225621132883364342433423444433344333333333333444444444444463333333345957555554455466677554676534A55667876867986869544564686675666664D8754433433898A8898889-65B45D469643988696B86A9A685665585555769333333334443466633333444333333333333333333333467B73899A7C9AAABA77789ABF7778679AC9BA834889E76788BA8C7567455556565666666475685A46556555665397A67896577787D66555554444454544444444555544986985B888777777778777777877772-4966622222275757668888898988-8889A78898898888889BDB66776978799999988987977767678627888888588882237666669A9A867785455663555455567777768777B69999AA9DBDDCC89A96777777775666966665666676666666666555544543333331111111141311111-111-111---11111111144534434444765 4311678-F44245679B9AEEBFDGE8867566637777677686A998DECF6AA9ABBB7786774876769884887677766889E8978C8888A57DBF-4I9BCEDFFDA9A7988FE9M6U*C-EACA98AC8ADA89A8898AI7AABA6AA79668L7AK43756HA9*9A9CEMHaZ9KMCAEVCED * c.2.1.7 Aminoacid dehydrogenase-like, C-terminal domain
[ 140] -----------------------1--------------------2-1--------1-----------2 -81-1---------------------------2222--23111-1---------------11------------------1-------7611-4-----12--322513--------------------------12223---9---------------------4----------------12--------1--------------------------------------1---------------------------------------------------------11-------1----------------------------------1---3----11---2----------------------1-1-32--1------------------11111111-1--11-11-1--------------------11-----------------------------------------------------------1---------------------------------2-------1------1---------------------1--2--------------2-----------AM--------------------------------1--1-21------11-----1-11--2---1----------------1112111111-1-1111211-11211111---------11--11111-1111-1-1--1111--111111111111---1-----------1------1--1111---1------------------2------------------------22222---12--11111----------1662154-----------------------------------------------22- AB56TOh-XEHC88M77AA7885869777677854764454555558A88B78FCBB78C886453441453333754553455454547D4785D56454E6diW2Gz********y**uz****u*w***O***ruyr*t***q***v*nc*z*********wSMaIKfJM*QNQOH*FCGHK*pw*7**8IMJFLN * b.68.11.1 Kelch motif
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c.1.10.1 Class I aldolase
[ 142] --1-----2222232-23-1----1--2-L------1-------1--3------1-11--11-11-11 GHY4r--2--1-1--1211-12--13111111333317234B8JFJE-FE917C41-2--4548Q3BKK7696666A92-12------MMje-J33---BX1A2nAL1M-----------------1------1-DEEML---M4A22422-1111---1----12125-------------54122II-53711111111-1212225866561111151-1112221-2r-111111111111111--3413511-11-131233551112422212222333111111111211111111111211111-121111112K22L6333333313-S3---553P3P1-1371-11---46--2236N-2---BD676-----3-9843346556511231232215-32B43947274-A885BB6FEB89475-21323533122--------322--23-111----1--11--11---------1-11--4-1-1----34463414555226B6666355262111--3331-3----3212---1543-----------235---2-11---3-----222--21--42344R123-------------------3--1---2333-l9-B-321313--1----1-11-14---1-1-------25331213333333333-23233343332333333315554423-2211-11--111211141112223--223333322333--1------2321--5-3111122------11-----------4Y22124433243443757-----------233-111113-4513NLLLLDGC4434---2331111111111113-1------------------1------2121-C8BDC2q51 ----CCa----3CDFfj*rlfkVshmtEECDCDDDECCCABABDDEidevltqyjkoibZYYEEHBEB9AFCEBKEDACFBFEFFGA99j*cjsjuPHKPEuSBCC-B*Ic6C88B88A9687AB79CDX*J-GBL79899799A97A68877H77AD967C6hnH8944E8BK4-AG5L676Hjz***n*yD8****H * c.1.8.3 beta-glycanases
[ 143] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 34--A9d-RCA2BAIBGFDBCCDGDABBBABABDCDBDADACDB9AGFDCCGIDFEHDDCDC9799992A998AA99599A99989DEFADGGNHCHA9CBDBHJQ2e*D*******wwvqz*r**g*i***P***yoev*p***t*nws*lk*y****f**WebbV*ck*SoaT1HIMSDEE9DPEPIDNFSYbyzyt * b.72.1.1 WW domain
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j538846C531563111122352357657888988766656699666645A754A4824666C8967B33G3376G56A4H822222222349DRBNMIKENOFUUQRP9MONMKGPHK9AA9CAIKB43334444434333333337663322MHADDB75F8ACICDFCCAHEEADEBABPM--3349A------65794675555555555-6545655556665455446877665775555666565565555745345546-645455545555--4622222446444G4C32334323233333444454444546A99894975B766465674443354346967BHGIIECCJNM5476677655433311RA76666633333333F5735445-1141144111154411444IO8JMGHJIJ2546 11--443-73323342332433354532222324224333233222222433573122222221211112221-2242221222211113423324233233243113E3A5593522333334752638I3-6392343533332433233155233734556521655-35539677p77787EA8E3C95753457 * a.211.1.1 HD domain
[ 145] 44112114AEBB4B5245876356B77A5B45CD7324344447A5CB46ADG395678784444135 BAa5L32543222143444-42117744444468685968BJIHDA9619798BD71622B892G6CJED955665565465912246DDEC3E9A3--8GCFCDGP9C--------------18868D97A7H7MOOUR155MBAIIHGHL54449663478C7BIKIG96635748934824344542646525266353546645524457641354422334442247222333333333233524358542332311299224723432466944342222444556333333322222222222224332233332843G53333444444334411225242-274425458863243252441394CA77A-----A499A6447975622232233336-DADDEJBL3G6-A899BABFACB9ACF87331695663477777777A8659EC8-------------------------1---234B-544445CBC9A995666556F8877358A67854418834543144549337B633554-11--114576C52CBH25DC5RBAAF5IDHDCAO8BBCEEFE9B32421123212-2-------31-366624477A212-41221112512211133-54---4415------23331445444555443-4555514354454335334445332324-575444655555963312333331333233233233--2333234466463B414334232---13-34656561633-7545347D8624468165731121211115444-----2353386643446672231--A9AA9A88---111-----------1--12---------1----23152-2-1-CG59 117774I-64123528665466655644424557675545545555695669BB77666565545444254545534233534554434694654432224348A614S3rUVSXaVPLPMNPMcXNUP**S2WOfJNPMUMPUMLQOIGQIMVMQLRXKRLOdYACRGLVKOFB7568P77648A69A7644624348 * c.68.1.17 Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain
[ 146] ------------111---3-----6224-2C2------------2---------------------3E 6C6-455566635263633-35--613333335-838KGI2323-2332---D2B-3---89822427472-----------53-3-3------------8-A33------------------------------255-----44-582BB------2-3535--242-8-------2----23-3----C-33333333--3-633-33333333335863-2------62----2-----------3-2---2-22-2---22--22--2222-3-------------------------------------------------23332-------------------2--------2------------4--833D-----5A89GD9I634245555555555A-5853D873C65-5447B8K835CA9W365E---2-233F3333333333333---------------------------------9679--3336555555377779922999939587333B--AGDJ4294895-2-C6-64225622222-2HL9-2-2--3-32--2-336-7655A62--75E47P-3---3-333323------------39--3-3336-5-5-2----53-3---5---3-4---92-5------69683666666666966-6966666669666666666969336666666666666666666666666663-666666666666---7-3---3666862-355553533333339563366-3333656666C8B38DDDE96393--------C---3-----3-3336333333333555533--442222----------------------------------------------75-2 ------9-422-9BBdOVLLHMFXhRRAA8DEDIHJ4767867AAAaNNQbYcpFHlOGTQS798889498-85677388CCFF99233FKnOnHbEEDB3UGIGE--c6*UXPyayNRSMIUT*mUMP**Z6VUxUUSRaWWYhVUUSRVRGvUrZaHUfv-Gd9DKIKo225--QG3G112J9c***Y*t22HISX8 * b.6.1.3 Multidomain cupredoxins
[ 147] -----------------121-11-----1-1----------------------1-------------- ABJ3*64988732465677-7C118P777773REHEPUmm4QLfLY643CCEDGE759--JFP5qDni*lD6333D33-F*O6-----9AA9-922---4C387U5P3B--------------1221334561-4888H9655P5I5974442212553677461GDEK214111113111178521--2G9866666778686679AA799557A6395A822222222CE444343444444444135312-1-33-1---222333221-1-211-1111--23222222222222111111111111122322222321728921222222332143-2114-131D4222A7452234163162-1-816E568-----ACYDM83699BBD6656665555B-GIIHLRHNAPA2LJJKMHQQPNNK34674EBAGDEE78I3333333314213986--------------22--------------7GU7-3A966QILZSURLKKCNNQTSRRS8SdOPOVbb23IKRJRC74HGMGQ85A6996B941111111129ABA69A222A3-643361335324A45CB8BA5C2111---------------------111AA5976A7683688A97AA888588795HD---1723------P9689KLHLMJIIHIIK-KKIMJGGIIILIJEEFEEFMPQCDUk6KGKLJJLJKKKLLLLJVFA9EDGDG-QCCCCCBBCCCC--M367545565427F7D222113-11111--3333331331258RTQVLPFNGDDECAIEL---------26577AAAAADD7FG9A7797755611111131772233--------2-----------------------------1-------4L-9 -------------2--------------------------------------------------------------------------------1-------------1-------------------------------------------------2--------------1----------13--6---214---- * a.4.6.2 GerE-like (LuxR/UhpA family of transcriptional regulators)
[ 148] 989FEHC9BBBBBBFDFAEFCFEE55582644B8FEECCBA9BDHEFCIJNSKKGJEDGEF697K344 ACK3D2431111-242377-73--46676664444485543DCC12126211213121--A9959463564222232268BE388969GD7B4F34---2443365423--------------2C85C9G888DH3558AB7B52C8FEAA9474465555477679AA934333346333453311C8545699B9BBBB7BCCAAD669958BB976773574444449A8666666666666666764541-1231211144112222111153544455474664444444343444444444444444557775554IHCFGKKKJNIJCLCFCLL8787ADH9788D9GOSNFOBALGDCDHH8572E75227-1--19787B544AG76821212222222-55966B6726435445AA7656575745542865664354444444487756D5I------------11111111111111-2114545422225667667855545545544525646A6A723566642334427442456554852222222544C8C5RMHEDPE8PQJHH5MTKNNJXROAAHBDDIV655A4534535544434344C84675546746563435657773797887768C7991-35665321111C695896999A999AAA-998A99CA9A9BAAA9AA99C97AC799CAAAABA999AB9A95997AAAA41777677777777-136333334333A67556666555666365585554545543A498A9988H67767A555211112111359B7555554B5AA4476666667333344BE664466--------422------------------2------7CL6AEBDDE8753 23-1123-4111122365333344242332322444343445522223344434133434331111-1111111111-111111112111236111----211223-2B39353344221223335172ES6-5543214423322222132321532623424441211423423535a7444434594326A42546 * c.1.28.3 MoCo biosynthesis proteins
[ 149] -----------------------------------------------1-------------------- 56A2c373333645ORPRR-RJEE*HRQRRPLMJJKnaxu1kWi2112141132511511lX1-*Er*X*4-------11-21222125312121111-37112o14-211111111111111211-12-1111122267111c16AB6CCI11112222113-1EMHs71111---1111-11-111161-*334344348354694-177AW32B11-2111111111p1-11111111111111-----1-11--1-1---321---1-11111122211311571111111111111111111111112112221112-22254344844242X2BB21111-31-14311223--2---1111-132518511211122955482325D14233333333322-65B6A643362-277B213111834A23-4241312-232222222224324212--------1111---1----1---------222112221385564VSPRXN444Bqmrn9p68443431256J113214253842131-1241113111132613314743126621222-767922K274534**13-23--1-1-211221111211111-2255--186212756666F5756666557668---1431------A2U21321338188211-311111413334411111122492MI321222222222222225122211211644555332353111256454766751J151-1-1-1-----111335631511-BG997AJVBE374651LKR4---------222D222222275634323222232222--111111111111111111111111--11-1-1---11111-11122-222222219-1 118Cis6-311-12MSOcLtehq**w*EEAGEEhpZOSQTJQREEEfYXyhZaaMNesZIGH3332211312323221111333334739J8O7H6222232I879-3N8J866552345245352292Cl5-67C123282471343--7316363332242842264BCBA361DJ5pQ4AFP7989g6A313332K * a.28.1.1 Acyl-carrier protein (ACP)
[ 150] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-111111111111111------111111-1--3----1-----------------------------------------------------------------------------------------------------1--------------------------------------------------------------------11--1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CCDGijM2L45EQSWKHFJNJJGGHHIJIYLFINOODIEICHJJIHJJILJNGM9GEILLIKKIGGIH6GIHJGIKLCIKIIIJHIFDGNXHHOLRCCCH98Kho*BV*guqofr*ubceYboZ**Q*c***I*t*bdeRuWiyfQlYSX*WQ*d*qdeJbaUWSYMpORjNlhReYXS*RQPPSz*s*K*uVYluw*q * a.4.1.3 Myb/SANT domain
[ 151] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------221--------------------------------------------------------------------------------------------------------------1----------------2---------------------------------------------1--------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 22127A51XFJ27773363334333343333333333333333333443343533334333343344432443433434443333333346434443332232CAF-8NW**********x***********7***q*wt*x***i***w**z***d**FNeDMNFAUDIlXLTE3662122134969849453ALDB6 * b.29.1.22 SPRY domain
[ 152] 11--1125212111342-44244-3224151-31312-141126B327-3C88123232124531--- 2596*649AAC554MECAA-AH33GUA9AAADIVWYPZcfBRERPG778OJ7OGGD8B--BAH6XAUgjY93333144329G7-----2333-222---16232L3713---------------2----21114298822F48852--311-2211------11-7233-1-------1---A543111265MJJKIKINPCJLJNKK69HHKNJIK579H7FEEDDEDFQT9JKJGJJGKJKKJJJHCCFK55L18844635KK6699E7688AA795555444A986756646665444444454444449554445556296HQCCCDDEFB9F5EML2597B636468441JGA733123421122228-6HB96-----96dPX748IDGHCBEAEEEDCBCK-89J99LADITI1YNNJKHLRVQJHGH9C97GI66788BN6666666686865ABB-----------1-----------------13CRB3CEB9NLQRQRNLFFFCOORSFFEEACWMWMNPH13HEL43865OBEDO75B22224F32222323---6324H754315177447-5772447458737BE333-11--------2-------111--237664636376569999695AAA896788AC2-224-2------58892743655356444-4425453554546443448ABA86445656666766756666594445554522333333333232213-1-11222223A3B---2-2-----1-1-6555516---91DCCE7A9E87B8A47771----------449333337774537999998883333--13554544--------3-5----------1-------1------2131223222-453 --------------1--1-111111111111--1-11111111-----11------1-1-------------1-----------1-----1----------1-----1---1---1-111-11131-1-241-11--11-11-11-11111-------1----------1---------------2--6-11--41-1- * a.4.5.28 MarR-like transcriptional regulators
[ 153] 444-2--63333314-A4-----64222262-----------------2-1---22-42222222--- 8685E24466622224434-46227K4444448EEE4686622ACAE46644A8A422--8AC6ACEFCC64444366-2-2D2----44A826------6-27A-F4E---------------22-222-22-2666AC---64442244222224444642424444422222222-222AA2-2CC2C4A44B4B8A849A988ACACC8C9984886A646888666K4666666666666668888C86C-6C28224AA98GE64866464444422222--444444444442222222222222422---2224A62682222222823A6--4442C422-4662-22-2--822486482222-82222-----8-8CC422224226869668688G-222222226C2-KDDCHDGJJDQP22422BCC848CD6422222222EBB6--2A------------------------------2723-22224BDDDDB78AAADD9DACCC8CD9B2245--224922224254BH2222---42--------2-2222666-222222222-2-2222---222248----------------------2---2--44C246--4444222422844444242446--24242------I9CA3A6GGGEGGEGGG-GGEIIGEGGGGGIGGGGGMMMOAC886GACGEEEGGGGGGGGDG86A88AA6-CGIIIIIIIIII---2442242222-484A888E2E-68866AA8222222224256AA8A484A62224466422222222222226222222442422647442222222---64444444444442462-------2-22-2222222222----44C44AKCGC2822 22--448-B6A23866866A888A698888888888888878885598668886878666666886892668868884878888782227A787778664486CCE-AC5HMMCC9E9898CD7ZOBHCm*E-OKO999EJEAKC996B9BAAK6AC8DANF6AAADaEIE78E7698Ao66684E8DF6EAAAC789A * c.55.1.4 Glycerol kinase
[ 154] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------2-------1------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111----1111-2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 9999LST-gHF6KKKIGNHFHIHGIGHHHFHHHHHHIIIHJGGHIIGHFFFEFDFFFFFFFFFFGFEF7FIGIEGJIBJJFFGGFGGGGIQEGHHIHGGiEFEPLQ4ShM*****t*rxrxrwq**l*****I***rnsl*mq*pjoorfypq*l**qpcw*iZakUnPQ*PbkTBKLC*BDCKNSbUmIdTJINPPQN * d.3.1.9 Ubiquitin carboxyl-terminal hydrolase, UCH
[ 155] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------21--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --12C2M----E--2-----1111--111-------1--------------------------------------------11------------------------P--*******jVbWlij**Y*c***8*u*acgc*fr*sQmmZY*XR*l*pj****j*hXMQKG*k***---17---3222-5-3-------1 * g.3.11.5 EGF-like domain of nidogen-1
[ 156] -------------------------------------------------------------------1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2----------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------111-----------------------------------------11----1-------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------ FIKM45*-i31*--3-----43-8-7----------------------4-9749-----------------------------------8-3-8361223-4-----*Jb*******siwku*u**e*j***3***frmi*lz*iW*mpf*ZW*z*xz*bhj***TE*bk*Se**5K5BtPR8*5--2-----52WFP* * g.3.9.1 Growth factor receptor domain
[ 157] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4333aaN-G7B5AAH7566566666666666566666776568666555555555554555555544414434554433445454556656456584444555FHH4OcR********ywp*****v*****G***m*zz*x**yc**xo*zY******Ugr*inVV*WZ*Xp*Y2655Y44445GA9J6HN22CGEEF * a.40.1.1 Calponin-homology domain, CH-domain
[ 158] --1---12222222222----------4---------------5--1D--231--2-222-2------ DC*-H24444444-33543-35--5544444465554555585877636A68697549--4552C-2RJE644664442--1311---44C31611---37123E7E56333333333333333---------1-57643-12C135738843333234333242W4355333333333333655----14315555644645654652333-255621334523333328D2-------------------22-112--11133112213----2344446646422344445443433-11133331111533---2222477254444444542722216563-9321584-11231-53-323B4-22816111------475D744365G66------------AAB9C787524-5446775887553-6112468B884115555555535517378------------------1-----------131-1-3334544147579994456BBA9976446562--788324--C4158-22634247--------2163411431-433132111-73973B82356J4O919-----------------------1-44A9472G4-52599ABB46189967819619--24224------7A656667667777776-6777677857676777777898553318868788888888887A55577762-755586656888----------1--5-825333343-33133333----------6H66766776755566666433233323259999A9A99A9AA63888897771111--51223322111111113-4----------1--1111--------63624424445R14 --12***----155642551231313222222244333332331227322664533613333111111-1111-111-11111111-1-866273C4443466325-4L2*OLLQGFHDHHGKFWEDIFj*R1aJrGHKEMBKKNFKKFF*EGdEHE7JRW*4LL33534421W54aaG*LGJ76gAFM6FD2I5N69B * b.1.18.2 E-set domains of sugar-utilizing enzymes
[ 159] 22122323333333222222222542232224222222222222222222222222222222222-22 3381c121111121IOKOO-OM99iCOMOOOHKJJJK7EE1cCY5153344156432611cJ51t5f*Ow2--------111311311422215113--5D876S6A371111111111111113211311121144454---U166555491111331332211ADBe41311111311114253111135o77777448776844548448M5753446711333333R4144433433433433344433233333323244333335544333333433333493333333333333333333333334333333333243967777877484Z3996222145-17324222332226522262224217777611111A62442125744422222222222-44A47425475544454433322227464325313234511111111122212311111111111--11111111211111111-2185127645666FEQDIHLH22C2VSVW8X99B1411113481191152348311412124121111112221334D7951234131111856822J446535ry7212111333135111111111111112233113742226566669657675855775B1-31111------82R51111118177211-111112212212211111311243BD21111111111111111211111113-247567646565111147442887921D1211114311111111111111114225865585Q2616252169A21111111131118222223254222434339CB22221114112222222222222-5-------------------------112---4---3C12 1-6Acg7-6224343BHLBQJKOVmdW443524QVDBEFF7CE456OJFOIELJBAXQHCBC222222-222222233232222222228C4H348444222422222S7L7444346597457978A58a7-5676656A55A47367567567955332457855E58GA7873ON5*J18Fc****IvW552422T * c.95.1.2 Chalcone synthase-like
[ 160] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----mlL-----HFK45776666665666566666557666666766666657566666666755666445244466466534555888EME5JGIEEGEAGCYZa2W7R*********yu*****x*****P***t**u****tl**sn*wo******QbmoeYTK*WX*LnfQ1-----------1-6----13333 * a.87.1.1 DBL homology domain (DH-domain)
[ 161] 112-1-22344434432322112312211114------------4---2-311-1212221--2--1- 58F-L342111322EED44-4I--CH434447KHFIGFRO177E2A41354-67542D--8AB3I7KACC4233334311277--11-1135-3-----55-4C81B541212222211222231-12212-12-77743---93A4576634433332423222865632212222232324593443352388888988476899551447378A2534666566655251222422323222232--11554244234256744544253336443332333212111111111112222222222222111111111211-333323344244233312337122-91---531--6421-322-1-2G-9BDD61111134ABC1126648722222222228-216427333882887576894F87755D45744153563444444442556258411211111----1111111111111-1--164H4335548C79DBA6668644D5B9BA57H9DCFAF-5A8744743B564G825142-181222222243314558252322222221-2212132212362FC44-11----1-1--1-----------32155-324625412323333344414428176---4788------53572437888787887-8777676667878777775578655545455455545545455454565672-455565556666---5-----875616862---32-11111-113677663534393A9695C8AD9B8865782--------23113-----332229ABACABBAB6545--2277-233--------5-1----2---4--------2-------3--31212322433 9134659-J743258DHNBHHPJVUZW7787589B98B9A77D544GAKVMemgAHQHAADA7435332444545853552554431218B7HDJA555487B5541F*FWKJEFDC9B97CEBOG9L8u*L1PFV89C5L8BFB8B8B7D45L8C9AE9CC8AD86F89F7FG8AIGHvEECHKRhl*GjQHJSQNRU * c.69.1.21 PepX catalytic domain-like
[ 162] --2---1-11111---2-----1-1----1--113212222214322544566--------11-1--- 1--11--111111112244-421172444444723225431133-2-11--2115112--321---3132322222333-2-2111342221-111---11----1------------------2411221221211143---152B653442211------54219433---------------1111211133333353133344321111133411111-133333311--------------------77437842659551177222332556222111142222222222222111111111111131133211112-115666668665637655343A32122111322312221-13342211-2-3--2-----222131--222211111111111---22-15-4111--------1---142---1-111-1-----------211--121-------------------------------2---21---111111-111111122222-3114-212--11-2--131323213-311--12-------12321311412-2112-112-12132323323211551-------------11-1111--11255112-2--11-2-----111----1----1----2223------21111311111111111-111111111111111111-35311---222122222212221221111111--322222222222--11-----22325-31----------------1111111---31222212121111-3------------2--------------11---------------222--21----------344432-2231211111-43111111--1---1---2-11 8756KLG-WAB7NMOCEGIHIJGLKLJFEEEFFGHIEEHEHDEGFEECGJLNQWKIHGFDFDC9B9AA1AC7ABCGE3ADACCBBCCDCCQGEGCSCBCBCGHbXY1KMSNmtgznyUURRVYW**S*T**uA*c*KWSQhTYqYKUSOOmRS*YmZagIW*aFENLyGIzMbHC8JH9*999CCRUj*FfKBCUhVVF * f.33.1.1 Calcium ATPase, transmembrane domain M
[ 163] --2111-1------1-1------111122411111111111111422233232155434641223133 1413D42799A223D9989-8D--BK888889DFEFJJcU574B4536243-C89554--D871B9BBBD31222111213212222133333333---53235425311111111111111114444534453411111222-14213221111111111111122221111111111111-13--222-132222222222222223222222221223323111111112111111111111112111221-----1---------11--11111111----21122222222221-------------211111111-2324955565568582333466525232122332254322234554122122642211111134B7D1-38548522332331335177B57F5B341295523266658A9B11136B433435944444444733233321111111111--11221111111111111-128316EA9DD9AEAEC9AABDDEIAAAA5BKDMDMHH23B98B9385E9B6EG3B77436634444444332AFB23334436335444143422353444547933-----------------------1-558875A575A77777773787776656767B1-1463711111166565567665755577-6778755767657667668BBB765667677677677677776866655564167777777777711231111145554668C222213111111111ACBBC78366D2EEEFCFBABEHED9787311111111259886666678888566666633322222132442222--------211------------------1------42322232222--2 22--775-PCC298IHCGEGIFGLKIHCCBEABCFBCB9ABCACCDFFCNMLNPEKEDEDDFDAC6884C65C8BAB68B6GHGCP475DMDCAGBA7BA667957-3W7CBC9AANAD98AEDNL8K9f*G-JFM8687GADFB6C987G95NCECABCLW4CBE2866E56B77868w6767BKJdZFWPEAPJOQE * b.43.4.2 Ferredoxin reductase FAD-binding domain-like
[ 164] 22142653544554431233322BmKNbRRdo3352211111133197459EH312564622332-29 B5757756777766BA9HH-HP11QSHHHHHGRZXZBObO2B83D4C34222BHL948--FAL4ACj9MBD4444444-264L666663333-322---2B4FDA38M7---------------942A7B7877B666BB4468CGHHHGGAA899544453EEAHIHM5-1-----1----64377---4223333333333333334322124331215233544444433333334345443353442342A23325222BA553364635467622212221111111111111111111111111111111111111-111211111111111244--1---1--2--1555632-1221124---18MCE33L2111176D7CC6AHECE855555555556-GdJBMJBTEBB-6658B78B963C69433D538878D585555555545443BB9------------1111111111111-----1748-3AA37O99I9HFCBC7IIJTFEFE3E9IF8OQM13BBA787BE5CEBA5D59624138111111166764687QF3IIB4D9HHG16455453658AG8EDAZ222131-11-211111111123---555595F3648288644468D666B84DADE7--18EC9-1----9655A958888887888-8898888888888888888CB95566A7777777777777777885766783-544444423444--1322222842646786111434133332334A678839555E3DDED68D5AKAKF96443323233232775B66666575565522222111------2-22--22----------------------------------------------4224 ----9A3-----77F222212221222222222322231223322222222222122222223231-1-32-33311111-3333322213222223222123DA7-5--------------------------------------------------2C97ESE--------J--9BC9775H9Kgi*2wI--21-12 * c.26.2.4 Universal stress protein-like
[ 165] -----------------------------111-------------1-------1-------------- --------------------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 7567EEF4eJa989FK9868699999AJQ7A689A98B9BCAALB9CA9AAA997AA9A98ACAECCCABFCD7EBC9BBBFFEAEEEDHME9HGU899ALMAELJ9ImI*i**k**pnmr*ws**Z*r***-*z*lwsV*d***bmzs**ximVpjY*H7ZZ***9*b*Raz*7B*nD*BAAWSZbNgZfICJDCFBb * a.22.1.1 Nucleosome core histones
[ 166] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------11--------------------------------------------------------------------------------------------------------------------------------------------------- 1111kiW-2113GFJ768777777777777787777788877777788888798888AAAAAC9A88A4AA9A99AB6BB899989AAABKD6EDGA9ABCCBZXc3X4Pr*******tzpu*x**q*t***M***s*xu*x**xm**st*kg*z****SmmsUTgOnKQsOdQN21122--1228CFE8B31187662 * a.116.1.1 BCR-homology GTPase activation domain (BH-domain)
[ 167] 33211142222222133333322354433461111111232213121112221233333333222-22 2493E32433311456655-56226C434445766645HG3557655133539F9445--535777A7CA34333444114342233344451545---3425554744-----------------1322--12-333671112534346632233222222343245642222223322333224444233444444444444444444654444445569123333343437777777777777786667325544471215544461427A83233331----11-1-1-------1----111111-12112321111361685555555253335532226532143442781111431299421335167557-1--178FFE4367B8A666666665658-89B89A8GGD6-KHHABAGHDDEHD966268B999BA583333333378851445111---------1111-111-111111113458446A88EBFFEGB76666CCKD99998AG9JBNIG15899A79BAE8H6IG764122144333333347433435431--35112232232432347444435242322222222222222222222332339988965354676666576667586895761-13555------67786656667687856-6667877676686666666BFB785566666676666676667B77655564187777777777711333333355553688C3334551443443335565547666C59ABA9CEE7EBEE699A223123122345597777766777556555446511112223334544--------11-------1---2------11------32433242223424 2122584-94--563BDFADCDAJHEBABA9999999CABCBC999A99GGJPNDDFBCCBCG57455365665787488AA99AE3369G8D7A5FBEC718556-5P6IBGDHE95446776FJ4I6FyA-79C6564D56B725774753B9D8CD46F48A79E79B33E73AC7*56799KIUXAFBC9NELJE * c.2.1.4 Formate/glycerate dehydrogenases, NAD-domain
[ 168] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-11------------------------------------------------------------------------------------------------------------------------------------------------------- 65DDPNM1cGDIPRNHIGJIJIIJMIIFHCHGHHFGEHEIDHIEHHDHHIHGOMHIKJHKKKHJIJJK9GQQJHFNPHOPKIIIIHHGIMZJIOPNIGHFHJFSbX8LjNt******iWdadwf**X*d***-*v*Yjfh*dktnSkmZfleZ*amhh*TUSVXUYLrQS*LiTQDXTD*EEEHOjsl*K*Pa*SVOSG * a.74.1.1 Cyclin
[ 169] 1112313344444443-55345421332--2-2221-232232322141211--1212321323--13 2684C53333313286544-45227944444756669AA9373566334342779523--677576CFAD43433555354931--1-55452833--115223G2924222222222222222121331121-22223222-534223443244433442332346554223233323233A8735222-27556567874676896684337575452C342322323H84665656566666665444741213412---4444111--211112222111123311112111111111111111111132311222222943BAAA9BAB2935B773333C34232851167342-314-22323533227443-----44AB92318457522222221219-75857A684E7-6667666988577535286CA89C77E5555555537752469-------------------------2-4-243A27G988DPNNLLOKIKKHQQPUMLMNAHOJJFEID339BA8C766IAC8E97B81646A15555555--277617534245236767-A58465652565579122-1--1-----1-11--1--111-12297636453346496663344346335565B2--232--11111ACBA7E97888777778-8778977878878667669EEEDD645889BAAA9999A9AB8J579666651F888986899992112---------31B7C334222211221113998985533457FFHFGJEHGGGGDBB991-11-11--16669444448AA89447767748612222134332222--------111-------------------------11431323331743 11--378-74314465686BBC9DIBD88ABAA7C8ABBABAB887878ADEII98A77765588688585596855455598978455AC56796566658488C-5L5B7I7CBA867776AFB2D8Hl8-8AC4675959C54466568578456579F69BA9A54F5E975965a23276GCNf7LF98K8A8C * c.67.1.1 AAT-like
[ 170] -------------------------------------------------------------------- 7LN-21-1------1-------1114-----1211112E7--2----------12-------1--11423----------2--63955999A28333--25245H4B65--------------13337435755412121---31---------------------11-1--------------------624777777894887778EA557488837B4912333332M2-------------------12-1--------11-------1--11111112211--111111111111111111111111111---11111GH4ACAACCCC5A61C445223261--7134-bY8HD92BA6857113-CDH466422222B9FFF655CE99B44344442346-BAB9A9A84A41977777877798EG65486CB9BC46633333333A664378F11111111--111111111111111----2688965986COMOLONHFFFEMMMOIIJIAFNPNJOML23GIEKKBBBGGDEGBBADCE9B983333333656INMFdqLLOdUDZMaad6ZabZSSeIMgihkr*KS1-1--111111-2--11--123111GEGCBBEELBBD7GDCDCEIIHGFFICHKFKL--2CIDK1-1111E7CCA77DBBEDCEFCD-BECCFDDCCCBDEDDCDDCCFDA8988CAACACCCCCCCCCCBB88899AA3-7778988679A9--15111116666C7MBN2223222222222235565538232QBNOMPKNLMMOPNLFPNL---------89DEIGGGGGLOHIH89BAAAA889444421C16655551111111132-----------5--------------12122121116922 -1---------------------------------------------------------------------------------------------------------------------------------------------------------1--2-----------3--1-----------1--6---------- * a.4.1.12 FIS-like
[ 171] 11111121111111213-1-2--6533354542-4222333345425A66687--2--1211--1-12 6531533445413255466-651167666666644565663444654363325463351133724434643111133211113374562244-3111--48784A3745344434421322222443434444645554622253B679887664476777867768A87576556676675344541112556767756747665463344378754436562222221A133333333333332332233411-23-1---1111221411233223364513233222222222222222223322222244233444315426444344424241432334212465--4243194-4333441122215A34433333344467324546754444434444A-374393A6333133333333432359645925442263333333333444345443343322222222221222222222222226557344434667867655557777767646675657633675B746559696577DB44575454443477868C46655344283343-45647866767478D47412121111211-11-1111834AI556645799747667777586967B6668B781-3466K11111165345765555555345-55555555555555555546664445666656666665766557555555562655555554555222733333776674A45333433344444444334333333357889A556656567A645544445444999876667678977787787788855553376665555--------112----------------2--------33432333334835 77229B71SCE566A6876577778566656666656757676666367789775567667865B777488A968A97797889896666B68667A775545D776At8N9DDCDBAA8BCDCHK9KCY*G1IHT6CDCF7DHD8DA47D8BFCEEEDGBD8FC75B76GCKIA6DBI*DA8JCOYdw7gMJHHBCFE * c.47.1.1 Thioltransferase
[ 172] -------------------------------------------------------------------- 721A7---111----3322-2A22-122222-54442532ADAKi-------558-----862-A3C5543----1----A168AG98-------------------1---------------------------33333---34WLEECC11-99---3--8E5-77B3------------B-42----882777775672777777122233777554B2EC33333376---------------------233--5----5522-1-14111-----------------------------------------------4554A22222225261J774343511--3775176521---211113---7237AA51111124RII868IFEGL44554553546-NJIII8EO8I51GFFGLNJMNNEFE7AB82A27A55782--------DAA5-S9K--------11111111111111111-----8A873A9932EBCCEEC8786DDPTBBBB88DIT9GCO--IIEOCLCDN14U55GILJIQWQI-------98FNTV147346AB5AABAE-878H793FD111121-2B6641---------------GEGMD53NH9TOKVKUPbTUTTWQUMSSSRNULKPNQ--1CLCQ------JLC67KAHGGHHHJIHF-DHGIHFEHGHEHHEFGGHGKLFBB---EDCFFGFFEFEGGFFHABA788CB2-B66666645666---F-1-1-CEEEC3dBN---------------456551412-BPLMOKLUMOOLLKLHLNN-----2---NCKIHMLLMLSUPXWDDEEFEECCF3333--J-AA6489111111112-5-------------------------1-111-1------- --------------------------------------------------------------------------------------------------------------------------------------------------------------1----4-1-------A1----------1--B-----6---- * c.1.33.1 EAL domain
[ 173] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 77BDEER-K777CCOBABB99999A7ACCCD9CCBBABBB9ABAABBBBBBBCE8BBCBBBBCCCBBB5BDCACCDFCFFBCCCBCEEEFLNAFHGFFFFDEGPMS5JX7l******jlhfipj**h*i***9***elja*do*Wdpoee*dZ*jxnmkSZxdWTfPoPTikbRN9FA9sDCCDGMHPbCYBKHDOOMK * a.29.2.1 Bromodomain
[ 174] 55352354444444443465677676677677778898AAA977789657CAA98A897786684176 74A3754444444445555-554445555554555554563685535333343334372279339658664433343333743343545566463311127594674431-------111111-43433344464533998656484784443344644646447444763444443546664334343257677777877777878765776777966674444444447744444444444444444444333344343335544443433235553332222344443544434352222222222222344444334344276555545576656554554435325454654854349445544323568755733223447785654748633333333334-556658757B547334556765666435433475654335555555545555A6E2223333322---------------111136778468856677787799986655AAAA797664554444445574457686545A745487444444489698735474368575664596756575877675A66853544333334343443446845454885555846455655575555556655565312A76931122255675565555555555-55555555655565565555555577455556555555555466555555543555556555555114555555556674933222334244322222444543365454986A77575555655564333343335667655555767777886766666555555A3344433222221212111-1-2-111111111111211-11155456645553834 54236A4-L8725795677866788888887676766666577777867888876677766656666626676668757776666666657666696666567C7827F7F7878678576667B78E8Nt9-99C47689798858453672C79658BMO5A767779H8AB67889*77767976C7B988E8888 * c.26.2.1 N-type ATP pyrophosphatases
[ 175] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 543346H-G553AAF99AA98967857998A885666656575687A88CB99B8BCCDFFE845786448854679699754555A9AMdN9UbOAAA79EBURX3CeQo*****rgZu*d*k**c*e***5***Zur**cp*rUqjhPxaT*kqpkxUfQ*casRvOgULTcL-FCG*EDB8EFIMZESAinGDECI * a.21.1.1 HMG-box
[ 176] 11111121111111113------4HCDABDDC789997CABCB779A88BBBB476588A75435154 4232443232422222322-221122222222222222222223122353223443323322522132222222243223531212113212121121-373632142211111111111111122222252222433331215152332222222222222222434222222222222222612211221333333333343345343443433433442125334432375444444356654343343611133141112122641233415446475387332333334343433543454463355322222222433353343448687337554565333461242221232213113334112221311315417211125142111111111111113-12112112312111111111111112111114121113111111111121112111111111111111111111111111111115352122228322324222223332222222264233422642454724543234322222222322222232422231312231322132111412114222214221121211312211111111111111332221314312223222222322322322222-21212211111222322224422424321321435723344233233241222234322234223243332444421213522212222114221242222223333132222222423532433432111221221121222122311132212233333233312323222323323311214221116334112133233311161111122C6H23-314221122114111111122222221221122 CC9B89A-U893DEFCBECCCCBABABCCCCBCDCCDCABBCCBCBCBCCBBBBDCCBCDDE889898678888978778878789BAACCEBEEEA7BBBCBEEIBGOIYSRObJPGIIJHNLcV9SE**J-QOXHHDHPAJPGGIDHCRFHVHOJKGC97CFHt7ADGE9OOI9ADE*KGEGEO**p9**AB8D989 * b.40.4.3 Single strand DNA-binding domain, SSB
[ 177] 33----2233334643122222-3I66645D7322--3322232532224765-13--233-11---- 2-32324378744332222-281162222224655852662326433442225232431132633253532-------34357151113521-4-2111282B77A444--------------2333321-233-444442224544553333323122111341258431121111111214C4442--76455545585555A55564444455667544333223225434445443444444437448411111121-11111114112113335222111422-----------2222222222222233222333449C6B8888888585556656655-53454432F85724464573372335334119-----3311461B216115566466366D-6643C594B36-188732A6227928232B2654553333333333333342425-----------------------------1-21324444566666545666B95456662667E575I25AD4473HEBC8643B7D67435533444445D3546333333342434462353244327332234445452333232244443444424121585736B43622644333362933D2322922---552A------33444333333333333-3333333313333333333435444455353575555575335433333331-444444444444---71111-222354333333434-24561--364567434557658BG555666669A4441----1---25556444445545553--3---------2243553322--------216---------1--------1---11145422333333613 ---1A95-842179967ABABABFADBBB5A8ABB9AB9B9BABAA7A9ACBCE9A9AAA9A8774652643678453357667662226877374222433369E-6K5JSIFLER789DBE8RXEO6y*R-sXt9EBAG8EGFEG97DMB2wBcODH8Iq5D652556Q588J2A9B*548AB**m*C*h64IQKHD * d.58.17.1 HMA, heavy metal-associated domain
[ 178] --1-1------------------5H768-BAB--A-------1o*2Q*47mIO-11---11---1--- BEL-8----------11----311--------312111213528F----11-114-------3-423GD83-------1131425621BB82-632---1H27-AKER7--11111-------212428111HP1IIGECA49J5JAV*88147551-121--F48ebU7-1-----1----D621164485599A9AB9A8CB9BBB788867CDB8DD4645111111H4-111111111111-12---1-11-11-1232--11221-11-1----------13311111111111------1-----11--1-----1-FH2MA99C98C5852B776564-33116-299ONEOFS4KG6557111-56DABBB2334268PCGCA5ECD9F44232333334-ZXVcMNjZCA91B77DIHHDLG9D65558696A9BD793222222223332-QPF11211111-----------------1-11-36634-11-39AAAAB47665CCBH888848BCCAA85--664GGD68CABBB247O754DGB11-----3389BX6tQRINbI4*IXXL-bReHKCcLV88J9JhRf4-2-----------------42--11176366C86779766677A664638467398---4AF9------63846255555565654-4565645555455345443564421615434355445465644622222254-B25555555555--421111-355572537---------------11111-212174CDADDGEDCCCBBEHHI---------5567877777995AA6557777344------I-CC9ADC------------------------------------38245122-21L-6 -----11-742---632112221111---1--1-11-------11113111215211111-1-----------1-----------1---1--2-------11-----5F8-------1----------------------------1----1------4---------2---22---2151-122G64D-B255Raod7 * d.110.3.1 PYP-like
[ 179] 441--12-------1-3222112-11121-42-2---------11--1--4111------1---1--- -------1-------11----1--11------1------1-----1-21---112------1---------1---2----121-------1---------1-1-3-22--------11-----1--111---1--2---1---14155221323----1---2132424D-------1----111-1-1-12-222-2-232-4322-41111---3382-1--12223352---1111-1111--11111-2---13-23-3323332-321--1----311-1--------1--1-112--2112111122--------1521112--2--1-1-2122-2237-11121-31231112123-2217----14-11--12--2--1--1-2----111-1111113---2--532--------1-1--1111--1-1311-1111---------1---21------------------------------2-11--------1--11--1--211-4--22----211---------1---3-----------------------1-111---1--13--------21-1-1221133---11-----------------11-1----1-123--1-2-111----1------1-------1-2--------11-1--------1-1----------1--------1---1-----1------1--1----1---111----------------------------1-21--------1---1--------------1-----11------1----------------1-----11---11-1111------------------114-122---4-------7-------1--1-----2-11-43454-3-- 952275P-*QSXGAV6GIJACDA996BDECBCC9897AAC999GIC8775EFAH89JAED6878466917AA732B968BAB96167CEI9CGKQADA998AA9AE-K29*******SeWSana**Q*T***A***TVNQ*Sb*tOeWON*MK*P*hcxl**NPOMN*Rg*SmhF3jmCtJHIKSGLGPHYG29DDLX8 * h.1.5.1 Tropomyosin
[ 180] 44767633333333544465553944442444536AA8888886858687678B55654564777244 4DI3722222222222233-321142333332222222224695322322322222221165445355495222223369AH166666887737763225665566736222222244444444CBCBCE9CE9C8996798664877888555555555556867987735524334325443644884475555555655556555465555555656532222222275544444444444444444433---11---------111-----322222222322212222111111222222222222221122211128D9EFBBBBBBBCDDKDAABAAACCB9857995EEC8998C78777A88847B43443543545B87335CBACB66566656665-79DBB78849325444875745447645476688877556666666665544G8911122222222333333333233332222145466444345555556777655567777695565555454446476667685576965559833333333336797cLWD9C89IAAB87OPRMKLOGO99B9DGEL768666666565655555557766655776555835448878778B788778A97AB213256522222276567536777677766-76667776767776666676666653566776776677676775664665621656466656666--1522222333373725555444432234444554454455565666645566645585553222332324566866666667775545454444222212A966666611111111732-----------1------3---111CE6CCEFEFE3646 2222334-6232323111111111111111111111111111111111111111111111111111111111111111111111111111111111111112133313739A54442454443553574Fp5-94B4334734645445542575544523747433333363A45558y67686444914I5594447 * c.1.28.2 Oxygen-independent coproporphyrinogen III oxidase HemN
[ 181] 11----------------2-3----------------------------11----------------- CL*2222222222222222-222222222222222222222222222222222222222222222222222------------49G9F11---1---442888DLEh4D--------------2B6687766746A66A7---66654555344884446544456666514222124-221586AA----444444444444444444444444444454444------634---------------------------------------------------------------------------------------------------------------------4--3-22---------------C1hIBCG111119OcVURBIGFEGG8888888788E1FRMGONIPCE6-9896GAEIGCQRJK9A7Z8HIJIIM8WHHHHHHHHEHHC9F971111111111111111111111111111124KLA7CLIDOZeeYeUMEGGGYWXWQQQQIPeUaSUTh9IQOLcRCOKNONKSDPFFTCIEC97764474EHLKHXB-35--54322453-FBJBDCA61EGDGKN-1G8998547758664555555E62FP2266-8EDE799A8DBCCADA99988ADE8AC---BA4K-------2--1-2------------------------------222---------------------L---------6-1111-11111---C-----99A9H7D-1222211-----1--2-------GGBD8SSTTLLRPFRQQML777---------A555A55545B7A558644754333----66I-DD7755----------------------------------------------EI37 22--112-621-1111111111111111111111111111111111111111111111111111111111121112222211111111112111111111111112-1G172232211133--1461A37N1-66212341215321-222141-212421321111213622423313S12233535F1344371215 * a.3.1.1 monodomain cytochrome c
[ 182] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ --11HBM11-11CENHLPNQPSVTPPRLLIKGJJKLKMKLJKKIKHLNOXSWV*IVRHKLKLBACCED9BFICDBGJCIKBBBBBA6769ICLEEEHGIGBDDslr1R53n*****xWUOQZsV**L*e***-*u*QbSW*Sf*dNjXNPhYM*XiddlOQMRUcPHwRTRMkbI4KKBtA77GYf***O*NLISXcd5 * h.1.3.1 Leucine zipper domain
[ 183] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------*******yeqkx****j*r***7***czge*i***V*iYQ*nV*f****y**9W*WJZTRoDQKK------------------------ * g.27.1.2 VWC domain
[ 184] ----1-1111111111-122222-2--3---------------21-13-------------1--1--- 13A3E3333333335DD99-9533F5898889678793E84FCK47636457889333334454434BA84555555433373-----1161-311------------1222222222222223--------3--DDDPS---E3dFFNDD9AA22-1-1119BM6DEDF-------2----2-1--11-------------------22----------2---------42-----------------------------------------------------1------------------------------------1115311111113112-11111111411-141-22222----2111---53-C----------2111----------------------1--2--12---111121322--11-1--312341--1--------2--------------------------------------111-122-2222222-2222-143222212214434------44523435353228-231------------76693-34------1111---1-----HHEHo*-4------1-----1----------1---121-1A2-1--11---11-----1-----3--1-1-7-------1-2--2-11--11111-1--1--11-1111-----1---22211--1-1----1------1------1--122222112121---3-----------9-1---------------111111111117222211115111-2221----------2121111112321111213113321111--2-111111------------------------------------------------1- 8678PMF-SAC3CCL9AB89ABB98A9CBBGFEBC9BC9CAACB8AA8CDA9EBCCCCCAB999BBBA59DB799CFBCEBAAA9A888CHBAABDB999776JMO1I*BrglgxkjSJPNQUP*wH*K**nD*f*LPNLXNWcQIWQLIkNM*OdQSYHUVFXSPFbJNEBLSK3EDEcBEAFAIJRSBMB97KPONH * b.26.1.2 FHA domain
[ 185] -----------------------1-------------------------------------------- 321-K1-12121-1A2311-16221F1111117445ACGD-82511---42-484214--1-31C2D7G7-1333111-1AA3-----------11----51-11--12--------------1-------------------1-51-22221111------1-13442---------------111--11-3555554453435453214423435-1221213554327C12242441442224431223553644433339B443124512231122242222111111111111133333434433332211111114-522-2222332122-433111112-1--34-189--------------11-16222-----98H9A4433A3134454444154E-78887I7CBJ2-SDD8AEGPTOKUF853147E676699G9899999997A25225------------------------------19G438PICLdikondMJJKJaZYVLMLK7U*bXJaRW--QLMA7FDATFF5SJ9C323429812222121234B41---2131-26223-------11-88269L--2-21------1----------1---54NFA9A3L8JF9HIKJI9MTKHHEJKWUElM--11113------GHIBBMFEDDDEDEDDD-BDFEDBBDCEBDEBCDCCCSVSKG9CDLGJGMIMKKKIHNHGIU798AAB89-GBCCEDCADDDC1114111115555-4IBb43372B-12122222HHFEG7G353O4XXVXOmjZJWWWXCIHI71-1132-13ESTTDCDEDMVbKPCA3555443322-1--4-11--------------------------------------------------14-- --------------------------------------------------------------------------------------------------------------------------------------------------------------3----6------C--1----------11--5-----4---- * a.4.5.37 LysR-like transcriptional regulators
[ 186] -------------------------------------------------------------------- -----------------------------------------1------------1------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1--------------------------------------------------------------------------------------------------------------------------------1-------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------- DD8DSUR7lEFCQNPNQRPLNNNMNLMMMLLJKNMMKNMNLMNKJKLNLLLKMMKMKMMJIKGCDCDD8DDACEDFE7EEDDDDCDEDEMaLQNLMIHJLHHGMJQ8OtX*qxfhkdZWfYVhX**Y*X***2*k*VYXZmTZmXOXaYTbUdkZfZXYTZSVcbPLmSWaOShTGMMI*FGFNOdjy*NwYIJJJIKN * d.20.1.1 UBC-related
[ 187] 44132433222222223121121234324344-----11--1-1321324122--2--122111--21 1122533333322233334-35444333333465552366322223133211444232--3322332545411111111112322122666415111--345525222211111111111111132-321322334224411231546555643333212224331776531212111111122222--22122221113222332342222122121111-234333332313333333333333312223123133141224422244333321111111111211122222222221111111111111211111111111233333333343413221331322124221122231123524441112211322611111323342223233222222222222-353344323421222222222232222222222222222222222223222223211111111221111111111111111111123332221132222344122233322222232223223114322243333233211-743122--1-1-1112133233312122221112122231211445466213111111111122222222221233443332325243332222121333212112111-1222311111122242222222222122-222222222222222222311131212222222222222222222222222212222322223221111222222222223331112222212221112122212221222232323223223132322222222262115111112221143334333333333234-2211-1---1111121211111-12112111111111-2----1--------2315 BA89JFC-ZDD69BFCADD8BB9G9FB887998884698877877799ABHFEHBBA9C9B98866664B8587C98888778989A798DBABCAA7A77B9GAF1A*McXYPNYUODMNMQPYZGkJ**S1gQrHOHIWJPWJGNIIEKLGT8XPLQNbHMLIOCcSQYGLRMBPRY*PQRQMoglzC*XLXKNNPZ * c.47.1.6 Phosducin
[ 188] ---------------------------1------------------2----2--------1------- --------------------------------------11----------------------------------------1-------------------------1--------------------------------------1-------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------2-----------------------------------1-------1-------11--------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------2----121---------------------------------------------------------------- 7757SQN-WCC5TNN46ABAAA88B78B8897986B9A9A788868AADE9AC99ACCDBDCC79773468678578699C68766AA99J86BAAFCD849ABIE1Q*V*wzvxvndXWRZoY**U*d***9*x*VgaW*TkzdWlWVSyZT*YzrmqVrdWkrNIdNORIUcTAMUI*HFANO****C**KKUygxe * a.118.1.24 Plakophilin 1 helical region
[ 189] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2222----2---------------------------------------------------------------------------------------------------1-*m*lr**bigZe*Y**k*i***1***gtgq*np**OtZOU*VM*e**z*4CHH**A5C95733**-*v-----g--------------7 * d.170.1.1 Scavenger receptor cysteine-rich (SRCR) domain
[ 190] 22----3877877764-13231-623221-5A-----------------------------421---- 4433M1-3---512SxbKK-Kb--cZKKKKKScamaOfv*1U8X21231111745554--EBQ-7ALIENB---------319-----------11---1545654535--------------------------34344---62-1-1-------------------1-------------34444--18735555545555555553455445557AA8A11------42-111111-1111111----1---------------------------------------------------------------------1113154444444444-3222221-6-3-3-13-551363-17---11-2-31-JCCM111111-MGF442LCLHE66566663544-1161181658O-433233435445687N8376222266D--------7----773------------------------------FEHG-6D96G989AEA9588877EDCCCC8EH6KJZZX23EB973ACDI9AFIR113----42----------8432L67-----------443-6-3--56558633---------------------------32-691459714222234622225362243---11--------1-1---------------------------------------11------------------------------------------3222224454-D712---------------CCBAC7B4751-CCDD6CC99988A7445-------------2-----24-224421211222-------2666666------------------------------------1--11-1------4 ----DD9-62--BBEDFEDFBABGCCJGG8CBC99AFEDECEEGGG88678ADM99676888934211131141311111144454---9LAFA978777B9DKIM-FADUJYEEGIDAECFHCQHBPDh*J-KIVDDCEJACMD6ECBBHD4LDEEEPHOQAOFHCGAEFKTHO2577t65587B59IB7943RHKE7 * e.6.1.2 acyl-CoA oxidase N-terminal domains
[ 191] 33333333333333333333333333333333333333333333333333333333333333333333 4444733333333334444-433343444443344443444444353333334443343344434356653445545444444333335444344433333333533433333333333333334444444444444444444445554554334433333355444445333333333333444444433334444444434444444333334443334333333333453433333333334323333334433334444444433343333323433333333333344434434333333333433334433363434445655555555455544555553544445445544455444444444445533344333344454443444443333333333334444443344334443454445443333333344543343333333343333454333333333333333333333333333333343334443444444444344444544444444455543344444333444444334333333323333333344445555555555555445545555566665555333333343333333333333333333333335434445444444544445444454333433333333333333433333333333-33333333333333333334443333333333333333333334333333333433333333333333333333333343534323333333323333333333333334444443333444433333333333333444444444454554433333333333333443334334444444454433333-333334333333333433344444444443434 9945AAA3SAA39998998899999999989899999B999999999998999988899888A7888837877786A4A8887876AAA8C8988C8888799EFL3ADIJ9F78FA898A6I9LfAaCN*J1DJc9789I79G678776789I9B79A9Fb9D8C9C8CKI9AAC8AA*BAAAARHcP9LD89DC9A8 * d.14.1.1 Translational machinery components
[ 192] 11----3242242442-111---1844945341-1--------12111------11111111----32 5EG3R21355511-GJA66-6U11JN65666BSPVRKLic-G5MCH3C-661CDD33A--KLB28BLRTL41---3312-21B--1--544313221--19344G5B63-111111111-----2222222322245556---ACF4677744344123643433E55A4212122211122AB42311183AFFFFFJHK6GJEHJEBA766BGGK5659CBD577688KB455555545544555611487-1-21-2-----33421121-13772225333233122222222221111111121111366232455615415111243123112111222411116-31-442-1--12-22311329-2HABI-----69UJL635B5AA79B8B989889D-56775989JNE-bHHGNQPZTQKOGCFAB6BAC6AB6AF3333333349932453-----------------------------18OpD36C97EFGHIEHD7786FFOF898839SDVDMFC12CE6BB986HHG2J8373-426B1---11111151E773331111-12211-44313134346A5BK43--1--1---1--1------------1199244286C757878758578874866779--16324-------174-5---------------2---------11-11-88943141-1--------------6-------1-211111111111---7-1--145441296A-1-1-1--------13333324122B1AA7A733A9869553621---------46697655688746CB9BDBA9881---1-2-444455--------1-3-------------------------11211-1---3C22 32--655-72--23689B7AA98ADAD8778776658DABBBB776446C5ADH6777766634423222314443333324444323213193231121-11323-2M5B6695534444545441526J4-549351344277646354315145487B625562314133436755Q44377849E6669945217 * d.32.1.3 Extradiol dioxygenases
[ 193] 22----5244444445-45331117EA788B8--3---------4-52E1645--------211--68 55A9768CDDD583766AA-AC446DAAAAA4GGHIAFNM487A84875973JBE69622DB8-97D9AC8----1-1--13F63668111--155---1647894782--------------222374622331CCCCD1118AA6995553556--111143369A94-111-111-111C77BA---AC599A9AA7A3C7AA97337743AB98B787CA111111A6344513433433434233114111--1-12111--21111-1-3121112---211-2222113232-------------1111112223-8411999997717-16---5556---33132143418---1---1--11A488443-----C7FJR6466668722222222223-66758685F55-7442455444776D4447587B7845644444444B2223643-----------------------------5435246KK7BDBBBBCB8886BBDE899737DGRHBAE4ADD785688J9JBIC686C143452222222-1146856H5D7E938B458186997GF437677987A3121---11-11-111111133677559686264356655785367778677766C7--16D7B------7464C848898887888-9888888898988888888CDD444335455555555555555488533383-455545555544---343444333287A4A3663384222223234444443131HCBB7B6E7EE8G86DGBC5553454359578966666A8554566676666731124383773322111111112-1----1------------------------------6618 22--436-G7625744325666647444333-3444363333444433445424333-333322232322222232322232222232355533443233334352-3L6A6685253242575972G5ajB-9591444723A65522-61343825A2111Q9324472EEA24F8EaABAJ9LCDD388A966547 * c.46.1.2 Multidomain sulfurtransferase (rhodanese)
[ 194] ----------------------1--------------------------------------------- -----------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2--199H-2---A7A44344444424444343444445255552423322444444442422232222222222222-2222222266766648543344244AEG1j--p*******ruk**z**t*****D***ouxp*j***e*tql*ed*w***xNs*iVViK*VYqh*bP--1------1-2474K22123331 * g.49.1.1 Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)
[ 195] 11574277898888983766666332243434455464554444435334545467464353212-22 6373833444444377766-69446A6666669AAA88BB3B7743523334444337228943977887454444442363534343435544222--254746644211111111111111143334534385533883336394894453344444435356455953343433334364334343347566666666667666654665666865544344444447423333333333333333233232344342324433443332315552222222233222322222222222222222222222222222244244444333354524552222424225444444754248455545322445433522222347883343537444444344445-887988885C427665657666986433344466555454444444443345A7D2211111111---------------22225567635774699A9BA6AAA99977BBBB79A955665235546564445684644864447633333334649972456448A466664365557567777676D866425233333212111111167454435556548475655555855555586555552-3976911-11155565555555554555-55455555555555555555555566455554454445555456555555553555555555555--3344444445593935333334133324333444444565554885A7557656565667555456555555567777766877687555555544444482334444--------11---1----------------------43333443334623 44116A4-611-677678876678797777777676565676677766677665567776666666663665566885886666655555A775557666686D7926K3A5556666463558B6375JU7-759345553578657575445467466DR58536G67D69857887*9A9A6GAQL8JG9CF6538 * d.153.1.1 Class II glutamine amidotransferases
[ 196] 2224-156544456451765865553343353222323111123222321322222332323243-31 3563E222449325BEA77-6I22BG77777ACGIIFHPN45483D54522165A425228BI3639976211112223E*N63622233532522---2732175737111-11111111113455454555572333234394887799667675564456655B7952453444423248654643154666666555566655596777655554595665555557B333333333333333544534414234152289111214331-433343112155543334234443222112221112255411144435HB7B323334363644875786A925-2536AZVB98546754453-23448744322121B6EAD5565658544434244444154754B5886616448467445554B6445A7454655B33333333543244741131111111111111111111111111133AD618CC77766B8864444889E33332397FCEF9447888567778A6B9675523184333433356574635H6857747588736359853426657464D34821111112121111111456373356547453776568754BD867A8CB5CE81-13454------65984854447476655-45458554644535545579866555555555655555655567354333341565465544654113422222445433648333222133224553766773433286988876864AAAA5443423223332255645655674666533333322211112242553332---11---1---1-12---1--------1----111-2211222123432 2411325-E6523435553666697834534555564555655676444599FE666465452443432544334562673555552335B45347444326364612C7A773666534273168385K*6-A5845255422144722353445744143563B5C74FC6445858*76643658B6555585458 * c.3.1.4 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
[ 197] -----1--5555555-3C11111-911C266-211---1---11--1--3114134241-31221-13 8As2I11299B12136433-38--3833333377783CKJB65ASZR23FA7VRV34A11A748G4GFKB52111222111-811---43B4-M22---3716GJ2d4L11111111111111133343133462455PL---4345554643333433433432454A53333444433357531-772724556563681656446NA77585633A91F449999967h43333333334432313113652146123226A22664463345554445222311433444343432333322222232333---222564-47222222242313111331752413241-221-1121-175772-362c755412222719A632232344EEEEDBDEEEE-86567476EN11UMMDTUWZZVSO335437G85366D762222222288A2371-------------------------------45923121126777797455588CC55555577A2241--537F-12156455C1232322421111111234-1115-11321-33---222322112353354834-11--1211221211111112--1-223244151-62412111131111111121431-1311211111186384747665766766-6676669675677577775BBC9A7528745666677669654C54546562-466676747776111-3333344444-54D222335111113334---1------C654344637244443745---------13436333333443544555554441111--3233443311111111-12----1--------222---------15421566563T33 11--425-8411287BBA9ECFBKFIA665655567544443454465BJHKSIBCA69666255233222662533233344434668ALABAA6QII864675714E5L8BAB846545456763A5GQ6-957152555562265535319453785646B815754B11939654s11146G88FABC9CBGBCD * d.81.1.5 Glucose 6-phosphate dehydrogenase-like
[ 198] 22-1-185567667881133321431112122----------------13221----1--12113-11 3286E312443242766BA-B644BBCBCCC78666AEKE2A9769533221565413--989379J9B85--------1-181211111---1-----1212142412---------------2322222222288866---34453355333334444432333445426322224223243355--2314444445643454565531124447444441-------44-----------------------12311---11--11---11--1----------------------------------------------4-152323343312-122222231-1-1--2-461121--52--1--1-423722411111559893366875555455554458-67766E7B7A61855878D778CB8533178755676683333333343343437-----------------------------31AA2277678A88C8C6777788GE888878E9GADBB2666788855B8C88C5574221453333333554B6719834345453555-354132232666678242--112211212222222222111344321462416122333322333333324333---7444------32112235324545555-355555555535555555234321342222222222222222232232222--244444444344---1-1112455563656222211-2222222122222223545288986A6455567454542313411211115222222322244322222232222223-332233--------1-1--------------------------11---2---4211 ----BB4-A52-346NJzgmWYMxmrjIHFEEEKLMDIIHFHHBCCcURjio**aYbgJMMM344354453353544144455574232GYNJPJF4445589554-8fEJ454546442244498365BQ61546243253472444445227457579E8498744274678737A6i554A8ONI*lmi55ECBI6 * d.145.1.1 FAD-linked oxidases, N-terminal domain
[ 199] 22222233333333332333333244444262222222222223433322333245443452323122 3583944455545369944-47336A44444677775576442443544445867438226553748898322222222243522222555515332--2424353433222222222222224332232223334554422254345444333222222223426445422222222222244333333334777777774777777654454778456574433333396333333333333333333334344344333333334423234344422332333333333333333333333333333333333333333243266667687464473355553232243433A9452333442222332723222422222224332222233233443443448-333332448G32A996668897874233339A55556762222222222232232222222332222222222222222222225335323333377787754444885965665688825332233223222333346242232263222222222222344435454234333354534354465557343221222222222222222222222222333634666455333344644436365356112322211111153533634444444444-44444444444444444444543343534333333333333335444333332656566545666111422222333322775333222222213222544463322222556557544766625442222222223222222222333224554544444333322243322332222222222212222-222222222222222222224322252222322 765589A-O96488ACBA9CBB9CDCCCC99899989A99899A98ABABAAED98AA9888899777698689977677799989688AHBBABCBCCAAB7EEH38HCXFFBDEEAAAA999FE9KBH*91CCH8BAAD99DB89BA9A78JA8898ALK9C9FACDFLBAFB8AA9*A8989IEJN9HG79GADCC * d.127.1.1 Creatinase/aminopeptidase
[ 200] ---1-------------------2-------------------------------------------1 113-1---------4A944-58--C244444654444322-254---3---1--------44G---11121-----------J111--1111-1------1--722-8---------------------11--13111-------DDQ599A----BB7496421B---T13-13319-313--------1---------1--------6----1----------------1-------------------------------11----------------------------------------------------------------------------------------1-113---3-----------158223-----12143----1---------------3-5--5--377----B--5---673155EE97C8AAA9A22222222587--3-9-----------------------------269B3-1-----1112113344--22555533211121--2--2--2--1-221--1-3---1---------122---52615---13111--313--412-----3-5-----1111---------------743-2-6433-H351322134-21124213261---I12---------1--1-----------------------------------1-------------------------------------------1622221----52831-------------------------232---21311---11-2------1-------------12-221142423345------7---------------2-----------------------------1-------23-- ----B7W-211---187635564GBAB444444BA93222222555338DDAFF326522121-----------------------------7---3---1-1736--*-*u**q*lRXOYUpX*tb*d**z4rk*XaZUkTXoUJYWcMlWM*Xme****zC*ypIROQN87u52MK9kCABL36UKh3M3zy3222* * c.37.1.5 PAPS sulfotransferase
[ 201] 223232121332122132221211222-1111331--1--1-12335211213232244541112-11 39D2842566552553333-3422533333335333988B1C889C542221348122119B72A58CA852111322-1116---12CEE9-611---26166C5F3E33333333332222344366235A3311134---74B787764443321212-342DCFC6-221---2-11-532323311232151565624546853155264462233311333322492--------------31--1-2212321212331142-121--1121-11---111------------------------2111111111-3384222222232231551222324332241112521312-1--1-4-151G544412221549AC53254B4222222222224-8686A9A94532555A4374244534281-24-2-1123--------3342-18-11-11---11----------------111-41521333-278879786665666B8776356A45667-27A774465744593443231-51----------31263422-22-31---132231113176B8GN3211--2---1-1------------1211223462666245333323344433434466--22111------212-2112221221212-2221121111221112111211342222111111111111111111111115-111111111111112111111122342C232222-1311111--122222213234344441285222332776---------2233322222553226654545645----123-332255--------1---------------------------1311122-1-2352 5444OOJ-G7446AAGHKFDHNGKIJJIFCGCEHFGKHIHEEGCCCIIHKKKOOGHIGGHJHJ9A56727569586655569BCBC6548GAHGAH5554869GCC-TphYGFCHEBA9ACCCBMC9KCY*H-KDM8CA7D8AEA9BA8BC8BL98AEDABIAOMA7DAHALNT87EH9f888SOYappHhcEMtzmqH * d.159.1.1 Purple acid phosphatase-like
[ 202] --------------------------------------11111------------------------- 3342244444453433334-53223333333333334544233322333222333333112213323333223333333222232444555525-42113556377836-3333333-323335222222222223333322242445455533445555545434444325222225222244433441655-7777777677777744555577755565555555557865555555555555555555-5556655555665566666554666666666665566666666666666666666666666766666665565755555557576555667756655456324426223243444515542566663333345444444444443333333333426655555534434443444444444488455444445554444444444444664222222223311333333333333321222454534444566676666666666666666666666665655586A8AA988869977766A96787777454698B253759444544435454556458888C935544444444444444444446444555AA8899D6BC9CFFFFGHHCCCEF-HGEGH215344533333387777998888888888-8888888888888888888999777798888888888888888A88878885197778777788822473333344445786988878878888776888878887878A888888888188888883333333339CBBBAAAAAAACAABBAAAAA9A9444433566644443334333374522223-433332233332223422244344333333754 7611774-S982333111111111111111112111111111111111111111111111112233331244233543243333231112421232111112142312kB8343346443244255254CO4-55334436345324542433443445-1339353422412337ABKfHFGA7778B1BAKQD8A9E * d.265.1.3 Pseudouridine synthase RsuA/RluD
[ 203] --111111111111111111111-1--1-1------2----------1--111-1-1-111---2-11 -21-2---11---------------1------3111-211-11-1-------1-----------111221------------1--1----1--------1-11-11-----------------------------23322---2-3124-----22---1--1--2414---------1---111--------------1----1---------------1-------------------------------------------------------------------------------------------------------------------------------------------1------------14222311111---1-1--11--111111111114-241411211--1243232122234111221221212121111111111-----2-------------------------------231-11----222222-----11-111111-3211211----121---11--1---2-11---111111121--3--213-111-11111--1-11-12-112234-1--1----------------------111213-1111211222223221121111321---1-13--------1----1111111111-11111--111111111111-------------------------111---1---33313323212---------------3-2----2----------3333332221--2222121231---31-----------2111111111121113212222---11-1----11-----------------------1------------------------------ 5656TSM-oLM6EGK89A989AB8888997999898998989989986A99ABA89999AAADDEBCB7DBDECECC8DCCEGGDG666FNC9EDGEEEF8BELNI-Hwkr*****jZfZebmc**R*k***3*n*YZaWsagneMiZaTncS*XtlnmLUTfZTWEVHIhMRTHBIGAnA86GDSMPa8VX7DXXWYL * c.45.1.1 Dual specificity phosphatase-like
[ 204] 11-6131--------5-1122125736N1KAC422-21122223127286um3-121D6124--3-3- -8e-E111----1-11122-222235222222235356331425184--21-31---2--441-2-7AGG3-------11-1---1-2C8C5-2-----1A12481D35--------------11--------2-75558222615-22-11-1--1------1-63574------------4392296-2-211111-11--3-122-----2------1--1-------1---------------------1------111------------------------1-------------------------11---111-2-----1-1--2---3-------4-2--51-11119512-21232--1--11q4226-----396A8---111331-111111-11-75455446534-333322424253-22215233444213666666666557553111111111--2211111111111111121223E21111123323342222222372222123273542113426C232632178323175821-1-222-22127323-1----2-1----11225341-4463IT-2-2--------------------113883222215252263343312233262233331-12242------23211332222222222-2223222222222222222343122223223333333333333421122221-111111111311--16-----222232733---------------4455434312665454373366655754421111111112221111112111244767663345545--2-331122111211212---1--------------1--------54312644551B-- 563-D9L-R9E6IDL4977BC8ADDIE76879875867566978B76BAND7CHDA9D67777654382763764333334544475778AB9EDRDB9483D9681DTJ*PQMORPFEMIPWN*mEfK**g3oV*KEIBcNTgKGWKHCwHClNaPQSEVPGUQEDGBFSAKIO4aKD*CCCHBRHKHDAN85DLILP * b.70.1.1 Quinoprotein alcohol dehydrogenase-like
[ 205] ------------------------22222222222--------4442222222--------111--22 4442544444433344444-4444444444444444228446554444444444446444434444474433333333433444434344441411222442444334411111111111111122222222242666663333466666666666666666666488A64646444646644424422422222222222222222222222222222222442222222222222222222222222222222222212222211222222222222222222222222222222222222222222222222222222222222222222222222222222222432142444424422222222122244544944444466465444444444444444444148448464446284446666666644444224222222244444444444444662221111111222222222222222222224366444444222222111112233111112223242444211612444445316664222222222222434646366543353443333443646444444445863433344443333333333333333442222422244621111133111111111112-2442422222231112113333333333-33333333333333333333331211333333333333333334333333312411111111111221244444333344444222242222-2222244444244444222224344244442433444444444644422222222222443333333344442242222222444444441-211-11-221222122221121211112122212124422 EA7689D-cDG6889666677677867998999777875767799976777777678579999A9A895899989A9689997999877BH96A9CE898897IGJ2CICOMWMMPHFFE9FKDTPBSFc*H-KJRAGEEVDGQIAEEDCLBBPDHFGI9FMDCB9BSHLGCAJBCJJD*EHDDDbZg*6kPEDB9DAI * b.4.1.1 HSP40/DnaJ peptide-binding domain
[ 206] 33113122222223222322211363323165223111-1111353332343212322233111--11 3231355977A46342366-6C33756666648679655723446566732286746522336751685524333344612241221156641412---362742244211111111111111323322212212344343335357663344433332333561479A32222122222226965532-35CCCFCEBFBBDCECCDBAAABABDC8969A7AFDDEDD898888868788888887888BCD98BA99B7CHH669AC8A798CCECABE878DDD8888A8888887877888888889CAAEE8788H554CF5555555C6B48776AC84538167632534543332343352273-45116-----6222993A4374222231333336-6843E595745-5555535532563B332915343322222222222343223-4------------------------------33-5134444633443344445533444434464455824BB3234C9883551738442272222222237342642531363423124221111212411328733111-11-----1-11111113111447547553222291111213-31-411-1511--2521511-1129B886A79AB9999C98-AA9999998AA9978987A9BB89775B9C9BBCB9ABBCBAA899888882-A8888888888811122222-334442235444645323224345322332134334334634444344435652111121116455766666669663211211111------483233432222222222636416-9566A6466668855722222223222221651 6654433-K63-24522435333333344524364535545544234344443612424434224342232231442-1223343345435322111211231313138466694586454444864A5Ct5-B5B31165444832443535F3964535B36236325A464548A5k7679EKCJM2CE4686758 * c.108.1.10 Predicted hydrolases Cof
[ 207] 33213244444444433522222253352561345222111111211111322134343341112-22 77D2B32355512134533-37113C3333327555979759478A725754ICG319119887BACDDC723334346112912111447717-----2414453A14-------1------122222222222AA899222873444444222233344312253345434334343333B7633553436555554472555434956646553257554544444466456565555555555445548352673343435339A524334342546554533333333343333344444344433426511154463616A666666676966--4776532644431-2--1-1711445445243145665-----52B89323766665545454344A-116114626I5-CBBAA9DFDCBA3435369AD9BDB772222222285535334------------------1----------22342123323BBBCBA98677AA9BAAAA8BBAB445322788423115675481132423531111111223222244211332262222434233212555556131111-1111111111111112111-4477A615116455555547555645464465--241331--111EA76998CEFFCDHFCC-DBCDDEFDIFDDCCCBCCAGDG68989G9CDDCECCDFDGDDFACC9CCDB4-999999978999112233333111132768555857134435565222221311174555548783444546582111121113566C5666677779556555555522221138222233111111111-2----3-1-2-2-11111211-----48754486663933 ---1575-76314356565667675785555554445455544665545586756667556644424435334443333333444344434655756566454655-4Q577B55843333343643639V5-5483443433743354332243333634538672D467438359CAi986C9QFIS5NF4796599 * c.72.1.1 Ribokinase-like
[ 208] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1123ADA-iLG1K8S11NIJFHHB2CEKLFF9DFHHAEFIBFELGQdo34FK7HGDHv7F35B686792EA9665AC8C9876B73D9AX*t1LPaGFF*8*GYi*2De3aVYRM*KGKJILWSsaGbG**Y6aUgNKKEXGP*NLLOHLTDLfKMJi*HOT*****C8SZBNOC25IF*D8FC8****M*S88R***6 * g.40.1.1 Retrovirus zinc finger-like domains
[ 209] -----1------------------1--2-1-------------72126---------1----12--1- 6EG2J11211111116411-161142111112567682212HDET4413662533221118762G73hfTE211112221264211--111--2------1---23122222222222222222---111-322-FFFCD---M3745E98612331111115455979A---1111111-111322--2234666665563656555444445566365642133322273222222222222222222221111111111111111111111111111111111111111111111111111111111111111111111332443333333432442222223271232433224344442433421136-3----------22-----1---1------------3121-3-2-11-1112-1-1----33-1-1422232122111111111----5---------------------------------12---1112------3------221-------22322--11154533765372345234221---------14771D714234-85112156346263333536S16-------------1-1---1--122121123252-212-----1331--1--43-33---4121-------21---21111111231-1111-11112111111111-1111-1------------1-1--11111111---11121111221---2---------31913-------1-1111--------11213455553234422216422----------422211111-1122114353433311111124PQ9BFD--------12-----1-112-111---11111111122-1111111143- CDCEHFG-mHD677C68998AAB9998777787777788889877777898898677A77778887773888888885887888887776AC8BDB8887776DFN-B*DRUZQSUMJKGGKKHYSGYJ**R6ZNmCGHHSHJPEGJKGGJGDQINKJJAG9HIFBAOCGMFFHB7YcF*GGGTOo***9*xNOWYUSa * d.219.1.1 PP2C-like
[ 210] --11--1----11---1-2222212-242422-----1--11122444----1-----11-11-2--- -32-62222222-2-22----2---3------2545-222-4-36-32222242242-22--522-33332----------141-2--4476-232---21--432--2525353222222221-----------1222----5-6521222222222-22431238443-------4----42322--6646BBB9BAAC6ACBAAC444486BAD445-28944444424344444444444444544444422442444422445442422242222222222222222222222222222222222222222222222-742222222225242433386862222188--5451-214-1-2---262-44222-2222-3---2-1-4-2122222222222-66464442486-34464474766622---82444444223333333322222122------------11------1-111-----142624A6A8HDDBA866666BBAC968846AFDHFBA2297726A988B68M24498926822222222244869A7342243222333267648666288C8FD24-----------2222222222-1-86666428-4244642322346444262762845--424822-22288666768888888888-888888888888888888866766664888888888889888866888868434787477774544442242222121-5344222443222222224666444666872EE9B8BAC9ABAA6CCE4462464442666644464567B688ACACC6995545---2--1111----------2----2---22---222222-22222-12--1-111-92- 3322GG3-733-113AA98BAAAAA98AA98995567776657AAA88BBD8BAABC9AAAA333333-332333331333333433338A5A5579779785GFI4BJ9BHMIHLJD9C68GGRP8ODd*G-JFL9DC8IDFGA4DAA9F86GD788A89E57675M54C7E63--13I43412RUYc8UC55Wiei5 * d.136.1.2 Phospholipase D
[ 211] ------1111111111-1-----11----11-111---111112-111-1231----1111111---- -111822422242221111-12--121111112434244323555854575535433455429242958832222222122-1---1176451522---2515352638---------------11-121-1-41----1-----5434332221111111112142231111111111111334----11-13333332313233322-11-1333---231122222112---------------1----4211111121211221111111111111122223223333343333322222222222232322122221-1112111111111221---22331111--2--1111-1-1----1-1224-7533532222343332223335333333333333-45344333452256627646565432233452424443244444444344532331121111111342222222222222111113244322222455454444444455555534445434422442423223242422222223222222222222262515421121121121-----2-3133437522212422222121211111112-113222224354353422222232111231122231-22222------22333222222222322-22222222222222222222222222324232322222323324222222221222222222222113111111222233633111111211113112222222322232556543443444452221111111112433322222333334343333454222211211111221111111132-------12-111-------12-222---1-------336 4611lA8-A4421122476C542449444543522244544443142c243647326*4345B32111-62222341111253A34111789465833413H37s*15jWurPGJc657A5765GLAi7SoC-77A6768887cA37856*71a975C*9NC*****422633*74Ir3O586D7IE8s4IN4DFACGB * d.151.1.1 DNase I-like
[ 212] 111-1112222222221-12211144443544-2---------22112-1242-------11--1-22 3243A55455435376644-4811794444448888867545AC7A773665687556119986E9A8FC6335545511223-1---2222-1------4112435431111111111----111122222212555341115233323421211111121232244531211111211118794411242266555835535576543223233A11335432322432322222222222222212222211433413233311332112216462332211533555454434342112222221222545444555334524222333332436333454412116351111221212112224133313899A1111146AEC54398A8977777777678-7787978B7991A886A889A7876657587767668572222222255522664----------112111122311221111116674244344566767544445587565545666543423223445444665A3447223283122222222353423311-2--1----1433253243534536635222122222222222222222222--7555577585654443464544444544552-23544------5A699796666666666-66666666666666666669997A7746666666666666666966666665-68887988887811173112234443564465664533344343556546543326755766A66575666676122122112365577787788897677878866944442151333343--------111----------1-------1------2323211111-223 211189C-G66365744765777858755456576635365453444466779A3684689753323333433234322333333354449647764566558899-9aERHHEHJHE9C9DHCTL9PCk*Q-LJR8DDDICEKFAEH89I78GBCECF8888LG959659ABEB6D86b8679D9DET7MBBAC6944 * d.113.1.1 MutT-like
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x*G-MGNA9A8898AC89A9AEA9HAGBBFAKU6E967A649ICCA9464y44477A34E68888G66AD * c.14.1.4 Biotin dependent carboxylase carboxyltransferase domain
[ 214] 994245536667866465644433788B8392-----1-----111112-41--56553245427-12 1215G21122212121211-1411161111118333365637-7A637352256423311BB55C7AHBH411--1--3-216--1--2232-2224--1112112122-------11122224432323442247889622-93543433412333333333116553332233222232354333DD1657CCEBD99C7A8D989IBAA97CAA439EA24333333UC2555455455555554332333354452232332245333434344344344433335533343335443334444443332244322223C9B7444564555754224444A2355615127755136H4-668453242111111111142IEJ326654A4BB8CBCB69BD-44743649CF11TIHNCD8MJCEBI533347985894BA2222222224411137-----------------------------1--1--A773D56655545555668855552555B54D9--2243543341E9CM3443-1153-------33353356922345226434221222241211115623------1----1------------1337723314243633333343333433334341--3221------88D96B89998999999-99999999A99A8999998BAAA87779A999A9A998888999998989A71777777777777-1223233244442-A4B555254466564236------1-14--2222332432222179A23121321318BB9666667B7AA11------------11-522223322122313D143-212-112--11----2-1-211188BAAGMHDF3311 --33582-6242233355455857A65443244454344444445555674588336454345575554653656453555555565554735443557343455613M38GFBDG954554577A4A5Jl6-C8E245574764266426338788684992E5A4933634323765o55577EBDL5EB4453331 * c.37.1.6 Phosphoribulokinase/pantothenate kinase
[ 215] -------------------------------------------------------------------- 433-4--111----4--11-1---13222221----1621111241--13329963AA--11524-6545111114211---212757777738661--6HG894FC663333333444444441123342222544474--186233-224222233333122-134212733222622339AD4411-F9O8888868A8888A888DPPET88ACIGID29DAAAAB9GC899999799999998777BL163652C111BCCC548D757888A2431---43422222222222111111111111132224422216LK718A8998837353889222E8H-1D649AFHQAF2X83ABBB6-1-4414552-11112224311111111----------1-11211212331-332333544344-11-21121-11225--------1----423------------1----1----1-------11212344445444444333344334444445435445--544234334321424483656644455555541442367547332O433339898AB8795535E9B81222111111111111111112224778756767579D78888B8688986865866--19646------64665566666666666-6666666666666556556559452246656666666646466565666653-455565555666--2666565777746658333545322122224BBBBBCBAAB3566664554655445656-111111114B8C988888A9888554444434411113-1822----6666666677--------------------------21424212324934 ----743---1-26AA978lHQGHJFT652222enHH66656621139HcJeVZIHCS7F9B--2-----------------1--1---A7897633323--39LB-2323685834433135486372DT5-748412541485252155247253661-133131I3335J331DK48556X4TEAR6DM-154452 * d.7.1.1 LysM domain
[ 216] ------------------------11111111111---2222122211111111-------1----22 2282422222222223323-22222322222223333333122212111112222112--3222324243211111112121---1--1111-411---2333312223--------------111111211232222221112-5223332333343333333242235333433333433333-----111111111111111111211111111-11221111111133111111111111111111112111111111111111111122122222222222232222222222212222222222222222222222-211211111112122111122221111221311111-1---------225-4655522222222222222222222222222222-22222222222-2222222222222233322222222221111111112211231--------11-------------------2446421111122222222222222222222222222222222222222222222222232222222222222222212211132212222222212222233234312211111111111111111112211211222323525424444433444443444434--211-1------22222222222222122-2222222222222222222222222222222222222222222222222222-222222222222---2-----22221221211111211111111222222121112322222222222222222---------233332222233322222222222211112112222222---1-111112------------------------------------321 BC77DDG-kIP2EEGBCCBABBBBCCAAAAA9A9A89BAABAAAAABAAAAAAAAAAAACAAB9B868576896899789866777A99EMDCEECDDDCBE9EEH2B*JkPOLKQPFDMGIHFVaH*J**f1VTwPGEGMEHNHDIFHKLJHQFLHGKKSTHEIHJMDIVJMIE7VUU*OQPMLfNcrCYOTZPKLIm * b.62.1.1 Cyclophilin (peptidylprolyl isomerase)
[ 217] --------------------------------------------------11---------------- ----1-------------------------------------------------------------------------------------------2---3--1112--------------------------------------2-12--111-------------111------------------------------------------------------111111----------------------------------1-------------------------------------------------------------1--------------1--------------------------------2-----------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------1-------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------1------------1-1-------------------------------1-1--222----------1145-------------------------------------------------- ----PD6-WX277A2121-1111323222222221-221212232313--11-131111322323111-12111311-2113322413124123A-21241314552cz9*jxoovsSLLTOdT*rHqZ**r4ok*MQPNrPfmiFcSRMfOIjUhXgjLKHGlDAARXMlBC6B1MN4*224ZD****2**VU5847J * c.10.2.8 Polygalacturonase inhibiting protein PGIP
[ 218] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 212298O-9347GFICEDEEDEDDDEDDDEDDEEEECDDEBEEDDDADDDDEGECCECCDDDEDDECE8DGDEDDEFAEFDGDEDFCDEEJCEFDHC9CCCIERTQ1hVI***x**zggbYfoe**Z*b***7***RlgZ*XjtfXlgcStfR*fvnglScaMYTIGOIMUDGcL1564F7684496DEE9658****G * d.189.1.1 PX domain
[ 219] ------111112112--------41--1-31------------12----------------1-1--2- 81D11422333431EEDBB-BD--CEB9CBCCEEFF8CEF-8-B452--32-363115--222243A45423222-1-1--1------2132-2------2-163-3-3----------------------------------414111-------------11--1-2-------------13511---2----2-2-21322111--23311--1-112-13-11111321222221211222112222111-2221-21332--22-11311-1------------------------------------11---111-1--2-11111121121-11-3332--1-12---11-----------1--2--9E448-----25631--24-133----------1-23223224141-32212--4632121413--2------13233333311112111------------------------------2B93-121111132223333122453333149345643-1433143--212-7--2--1-31----------111121-1---------1-----------1--22----2----------------------11-151-1114-1-11111211111-1-1121-------------1332-21---1----1-----1-111-1--1------23311-1-22222222223222211---------111111111111--------------22-1---312---------2222213111-41111-111----1-121122122222----111-1141-----36466222--------11------------1-1-------------------------------1----51- --12DF7-421-339ONbOYPYMauna9A9A98EFE6CABCCCBBAePCTSbtrLMMOAFBD414-11-2--322------55314113BWINJFB634554AA8E-5YG*UUeaSNNLKcVQOqiWZP**P6cOiDKNHRIISCGGFLFMMD*LKITPKMSU*Zg*np**ntPQ-285B23112BXWdOIH13H8IIA * c.69.1.1 Acetylcholinesterase-like
[ 220] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- UKDGJJJ-*OO5FFNB8BCACFDFABCBCBDCCCDACCBC9CCBDEJCBFDACC6A9CCB9ABAA887488A8A9A96998ABAA9B9AIKG8PIOGCFA88BLUP7TwCjovjy**iRNQVoU**W*U**wG*x*SQQRnPcojOfgQPcVQ*WedljGLLPaVJGYDMeStOD9MQGoJKGYDq***F*pGFaeXhG * g.66.1.1 CCCH zinc finger
[ 221] 22222223333333332222222242243434222111111136222433755111122222222122 2224444444444444444-444444444444444444444868424422224444442244444444444222222222422222222222222222222222222425565555446555562222222222244444222236444444444444444344456464444444444444222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222332233322234222222222622242222244C6A66544444222222222222446646226A226222868882AA4422222442244222222222224422224222222222222222222222222222222422522222264666642222442244444444A24422288222222242422222222444222222222224222222222224222222222222244444464222222222222222222222222222222222222242222222222222222222222222222222222222222222222422-2222222222222222222222222222222222222222222222222222222222222222222222222222224222222222222222222222224222224222222222222222222222222222222224444424244222222222222222222222222222222222222-2---------------2------22222222222422 AB88DHA9ZDC8BBAABAAAAAAAA9AAA9A9AAAAAA9ACABABAAAAAAAAAAABAAAAAAAAAAA7AA7AAABA6AAAAAAAA9AAAG9BAABAAAAA9ABFI79FHMEL9ADACAB9EEAEKAX7d*L2HINA8B9PBCLCABB8DCADIAEDBBFNH9E8D9E9AJ8EICEEEE*GEEAEaQgfAWLCCAADBG * a.129.1.1 GroEL chaperone, ATPase domain
[ 222] --311133333333331222222253334244222222322232222222222123223-3222--33 4464C54655565597777-78338A777776899979EE37655443455485766544666379A675645544441333755354444413111--34455434441111111111111113324432225366687212643334333333334334344344433443334444343334332224555555555555555555555555555555544444444655555555555555555555552134434-4-5533443443424443333233333333333333333333333333333333333333323334333333333333333222231124212322223323322212112434977733333578675538797866666666667-555556546783A88A87898A6666556667666667854555555644445773333333333--11111111111113333357653698676667766666666667777467789CA94466565756A7889B4465557653333333444757341224533333332444454533776776224323433333323222222235222335564544454454444453444464434453-32356------45563444443444444-4444444444444444442343565543333333333333333544444444344444444444411343333355553764443334313333334388888655455588885878955555877444444444444434444445444556555555533333331445555--------2-1-------------------------2-111212223313 1111556-732-5675677877677886666665557767777777565878A7666655557555554565655773675455554447A666555664657A97-884B686C7B6555665AB6E3U*D-E9F55566668656656B55A6D65C7GR4A644H65EH8B75785x55587A48D7798996669 * b.84.2.1 BC C-terminal domain-like
[ 223] 222112756667777724324224522324621111111111122-2-12453123224434441--- 4467B445667333D6677-9A11B977777499A98DNN57566765676287E4643355H577BB96512223331-125331334442-42212222274332321111111111111134534534253433312111444444444124422222323245474222222222222433552211535555554536565456633535552425487644444564444444444444445A77673718713322CE546756887266675564445544444434444444444444444445664446666324-344444444432533112262-123-11153152235124443144216844533333789565556466655565455556-6686898B6A53666698E889BB3E8767675655777333333335442444422322223221122222222222222222165882897799BBABC77777BB6A88883797F5C9A2356557366668583365423233333333357445336945444456444142525635244545414111-------------------213775558954545722332252422332223341-1787811111143435335555555555-55555554555554545545443344344444544443644455333334531455555555555113311111445455765222222222222222655563656433566765665668744435454453443445655555645554334534323222222434433331111111131422223-3-53222334352233---22123313336512 5511337-E5514433233243434333333333322323333332444446593334333322222212222233323422222233355323333333333546-5A7B9H88D67666787GE7I5W*E-F9Q4476C778757847655C7BA898EI48765E56A87975874*45567ADCD3C7AA9977A * d.87.1.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
[ 224] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------a-----------------------------------------------------------------------------------1----------------7D-v******qmvhw*n**n*l***L***kpxk*l**tf*nhn*Ye*o*zy*QdqhbUXM*VKiU*eP-----21----------546JFJ3 * b.36.1.2 Interleukin 16
[ 225] ------------------1-------------------------------1--1------------24 254-21111111115ACGG-GE44V9GIHGHFBDGG4479-347-3131---111111--342-3221231--------------1----------------22--2-----------------11-212---42CFF54---K-93252211222--111-1321568D-2-----2----11-1111-----------------------------------------1-------------------------------------------------------------------------------------------1---------1--------------------1----1211------1-1-133-441-----13cFD12173798------------76L57I9F-D1-E333MOVTPNPV11--1-21----37B1111111111111751-------------------------------121--1---211112-2222---32222113-1379------313--22414--252221---------32-234485311---2311--12122-11-1121EQ361-------------------11--1-----213--2--1111111111111111121---1122--------------------------------------------------------------------------------------------1111-15555-2411---------------11121-1-1-141111--1-1----1--------------------------11111111---------D1PP89JK--------911-------------------------1--11------4-- 686688N-YD*3ABJ111-1111111111-111111111111111111111111-1111111111111-11111111-11111111111111111111111115662BM**soq*deSSRPSTSokQnT**WAeR*RTQScNTXTKSNUJiQG*SQQWYPi*j*tbRsUV*qobX-**6K36676--5-1-1LSAJKMA * d.58.29.1 Adenylyl and guanylyl cyclase catalytic domain
[ 226] -------------------------------------------------------------------- ------------------------------------------------------1----------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------1-----------------------------------------------1-------------------------------------11-111111-1111111----------211121-11-2---1------------------------------------------------------------------------------------------------------------------------------------------------------------- 1---43Z-731121222223222333222222322322121222223322222222322222233323323433233133332322333342233323333234361923*******pqmirjo**l*m***4***kong*mp*Ygpkje*kc*n**rrkz*u*smLoMMr***J143------12253225--1111- * c.45.1.2 Higher-molecular-weight phosphotyrosine protein phosphatases
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c.51.1.1 Anticodon-binding domain of Class II aaRS
[ 228] --------------------------------------------------21---------------- --------------------------------------------1---------------------1--------------1------111---11----62--152----------------6121221111-1--------4-4-2122---------------1-32-----------------------32323533-322432------234---1---9IIGC7-1--------------------11---------33----1-----1111111111--------------2111123122212-11---1111-1-5-665766616-1-44----551-3-----113-1425--------1--1------------------------------------------------------------------------1-------------2-1------------------------------------------------------1-----------------2----------------------------------1---------------------------3-2-1---------------------1--------------------------1-1---1--1------------------------------------------------------------------------------------------1-----------------2-------------------------1--------111-1111--1------------------------------------------1--24AD--------2------------1---------------------------1 3222LXI-dIV5989333623442223113322334243323324252551333125554442851221532C5E321223MND8E-43466345823124346982bIh*cfflrgPHQGScMyuNwA**dAyc*KSMLiFTgTGSKQJfLNfMnaVrMZPKuYGKm*y*GLKQ2E7B*323G4****3*s42JUOSD * c.10.2.1 Internalin LRR domain
[ 229] -------------------------------------------------------------------- 7963s12577B11112211-12--1F111111433336EL7-2GUjU1IKF4WRU118--968AX6OSZL6IBCCKNL4---3-----2241-2------8-419-A4B------------------------1-67854---C----------------------1-2-------------68222BA-C7ABBBAB98C7BAA989GECCABAB868D28679BBBAA4Q54444444444444442257C791881C527CC99678559C7566777987855677777777877654556666555555744377778417E2222222A295611468AJ434122A--------K1-489991131-1FCC4-----5-765--------6656566656D---4--6135K--VLLFXSXhfbWT76A158E96557966--------56611--1------------------------------3927125524ADEEEB8433399EL656548BAB4664--666C151165A27G----1--3----------------1----11-3------------------5-----------------------------CCG6-77-94B5565734333412233115-------------KMKH7LEEEEFEGGGND-EDBEHEDEFGEEFGHCGHETUSML88BEGCDEEEEEEDDEDCDSBADDDCa7-KIIIIIIFIIJI---------------97D444759133334336------1---9744443659244451776----------A9AABBBBBDB9FG87AAAAA788-111---3----------------5----1-1---1------1--1----567623B544-J-1 --------11---1------------------------------------------------------------------------------------------------------------------------------------------------1-----------4--------------2--2-----3---- * a.35.1.5 GalR/LacI-like bacterial regulator
[ 230] 11-1-112222222232232221414443524332321544447645435565-32234331111--1 67-2b33422111183111-1C--3B111111D76AREAC2LLME641-685565118--OI54S8MIKK931114756-QH6121--7796-444----Y27298G-3--------------21152346BB2114422265E-D34A225-133-11-1-22-289G----1-1--11--2-2--111B96JKLMLGHPAHIMDFH85AA79HHH34393539437659E476666576588755433C7I28-7B225359965CF754CC5BABD8A8986AB9533338656547BEDC89C988A8B7753263574K5AILEFKMGJGFBBKMI3763A3964-JQ31KKND54145A1312132423J6761641788H67886454361-111-1-11C-767485666CA2F65C68ABFAE63655E65A383298A2222222298931B45111---------1134--2-212216-8813AA9-5532A8ACBB9A2212CB7BC5453798F558C-2866264A4G6C4B734213245353544343335333B461432884235-789A579545667CB423--22----2--2-------31-26335685783333-48GJ844451433245758---7135------434D14137853749431534629A3369A7343443558C5FJ82223323233224233623321222-322262212343--44355233351--B5334321132221742-4435562223A75675887968A664DD8-----1---224284822832134917544544571231-12445554--------315----2--1--2--------------12113333231513 -----------1111111-1111111111111111111111111111-111-----------------------------------------11-------------------------------------------------1--------------1----4------6--------8111--42441--------- * a.35.1.3 SinR domain-like
[ 231] -----------------3-1-1--A337A631------------------321-2----1-------3 1-b1-111------34266-53--935555564555-678--34-H8-----3-41----222--132222---------119-----JJWF-K33---6C23AC2R-K-------------------1-------1111---1--423--122-----------42-4--1-----2----2------4-135454545555555553-444455511131222222222G11111111111111121111322223223132222223222321111111111111---1-111-1-11111111111111221112221-1-42222222222451333564262---23-1111----------------*2112-----45A242--324-212221222224-13231211-77-5333235D76CA1416-2322123727--------1111----------------11221111-1111-----155413983446766736666448366664483444441-23112312722-3515532442325234331--331622--132--4221221121122-113188-14121421211147121211121113225642-1F3J22343334473554336965E--13---------7624684ADECABCC88-C899DBC9DADABAAAAAA76735656AGA99BBABAABBB8A685A77881-366566666666--2122222222212-3733334346626423622322121114698B96AA83988817552---------7BB444443495CC542222322211111-13784455--------1-1------------------------------11121-2C3 ----11e----2--144548665BAB922322244353333433333259EIOM98622322111-21-1--2-1-----111121-11--14-1-112---3111--*1*QVMPNSIMDECGGMGFQPm*R3MLZHJJJKHHKKCHED7LGHPMLGKKGJU4*Z6EOCBc44X1-L7-----2-2--22-143POER* * c.76.1.2 Arylsulfatase
[ 232] 11-1-12222222222-21-11111---1--1----------122-111-211--------233--11 115396577777679AA99-9977AB9999999BBBABAD497CB88657748A9568227887A8ACAD788889883-143333333324-232---121214342211111111111111222222222242777772239-898566533553423333557586423222224222264744112221AAAAAABA3BABAA9322221BB9322724377777746-222222222222224333159879976699BB99895665674333338444667444444444443333333333333744453444523338111211-313124322226251-5332143212--2-12222334314455611111234654333442433233232224-7877875648717443984765654479423222227766666666644434243----------11-----------------12532122222444444555554445555544444546412554764444454545542-1121111111122233223722212141112-313222332224255-331-11111111-1-------11223223224333262253333142355343333531-3232211111145434445555555555-55655455555555555545443244355555555555555554433555511433333333333112211111----3552333333312322122344544332454233334334343344443---------21112221223433344454554442333-13244555511111111212-------------------------132--111114311 4244558-I852217BB975897A9A75545664543454344454BC767EBD9B78656577A5654A96978986785BDC9C665796B57667775A7431-3*8679A9AB84855859A6B9GrB198I5688957B537868776E6985766557432D47768233GEBYECC9BKHBO7NSPTFHHFX * c.60.1.1 Cofactor-dependent phosphoglycerate mutase
[ 233] --------------------------------1----------------------------------- ----1---------------------------------------------------------------------------------------------------1-----------------------------------------1--11--------1--------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-111-------1-1--1------------------1--1-----1----1-----111------1---1----11111111-----1--------------------------------1-11--------------------------------------------------------------------------1------11-------1---------1--11-------------------------------11--2---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------- C88777O-U9H88AE355333453334878767453566654446555444334328452223332321222235321224322233336B556766655664B6919*K*z*ox*nnRSSWjh**P*d***5*t*SaRZ*VeujLfWSHpMH*YjbZkhoiftvEFfPRlFNvT1WTO*ABBGDw***4*SCEMpfm* * a.39.1.8 Penta-EF-hand proteins
[ 234] 22663287777777764666666666654756777989999997877766777A66677475554-44 5674664444444445544-45446844444476664565486764554444444544334544466544433333334545565554444435551--4544564444---------------5555554555645544666488655555556665655576445556555555655555333445424344444443334343334444443433333433333333453333333333333333333343-33333-3-3333333333333333333333333333333333333333333333333333333333355645555455554554444444635334456755555353674465733564444533333586574455654533333333334-54546556334343343334343476455445555534455555555555444454454444444---------------333344445455445555555555545568555545577558745444674355757655576644454444444555566566576566666665676666656666656566556666665616111111176656556645545444666666566666666666654-346451--11166556646666666666-66666666666664666666675466666666666666666666666666644655555555555--444444455555565466666635545544544444444446455555554555555545433333333644464444444444554444444444444465444444--------4---------------------------31333333335654 11--444-311-33333333333333333333333333332333323333333333333333333333133333333-3333333333336333343333333333-4418554659344346484674Cd6257H3635644612454553274656658859415C67A64454344Z5434453773464484544 * d.139.1.1 PurM C-terminal domain-like
[ 235] 22663277777777774556666666754756777989999997877766777A66677475543-44 5674655444444445544-45446844444476664565486764554444444544334544466544433333334555565554444435551--4544564444---------------5555554555645544666488655555556665655576445556555555655555333446424344444443334343334444443433343433333333453333333333333333333343-33333-3-3333343333333333333333333333333333333333333333333333333333355645555455553554444444645445456766555353674475733564444533333586574455654533333333334-54546556334343343334343476455445555534455555555555444454454444444---------------333344445455445555555555545568555545577558745444674355757655576644454444444555566566576566666665676666656666656566556666665616111111176656556645545444666666566666666666654-346451--11166556646666666666-66666666666664666666675466666666666666666666666666644655555555555--444444455555565466666635545544544444444446455555554555555545433333333644464444444444554444444444444465444444--------4---------------------------31333333335654 11--443-311-33333333333333333333333333332333333333333333333333333333133333333-3333333333336333343333353333-4418554658445435485574Dd5257G3522634623444354374636658858515C65864454344Y5444452663454464544 * d.79.4.1 PurM N-terminal domain-like
[ 236] 33211-42222222223344433252333361111131222212121112221233333333332-22 1372A11211111356622-241148222224422211AA2423534122217A4223--53424697A833222333114122233344451544---3425444636-----------------1211--12-333551112323124421122111111232233521111112211223222344222333333333333333343543333324347123333342337777777777777786676325544471215544461427A72223331----11-----------1----111111-12111111111361674444444253235532226321143341671111321299421334145334-1--158EDD3256979544444443446-7898977DDB51FEE698ACBADHB843143988897352222222266641324-----------------------------2347345A87CBDDBD84444499FC666656D7H9DD91466576776B5E4CD65222--12112222244312133331--23112222232232347333324242222222222222222222222332226674844344545544465555455564551-12334------45554444445465544-44456554544644444447C85634443444444444444448554444431666666666666113322222555424578222334-332332223343337333A4666668CA597BA5766123124112334456666655666333333333411112213223433--------11-------1---2------11------32433242223324 ----373-53--2329BABBAA9EDB89977778787B8998A778676EDFKI6BA98988F4634425445466546689989C3357E6B674B9C9716554-3A4EEDCFG854246647K5N8ItC-BBJ2653E68951644272276G7AD47845846J6CB22763754j55349GDMV8B974F9BA7 * c.23.12.1 Formate/glycerate dehydrogenases, substrate-binding domain
[ 237] ---------------------------------------------1---------------------- 453262222223225AAAA-AA55E9AAAAACBDED9A99255744523333455435227593977899322222221111223233434413332--56666324143333333333333342212222223255544---6156666652333333222334477732222222222223333322213222222222222222211113122211112321111112121111111111111-11111131222212341111211111211111111111111111111111111111111111111111111111112123222222222212222222322111422211211111113221233614244311111322222123333333333333333-544444543431522255455543223445442333445333333333222344211111111112222222222222221111133251222245444453233333563333344555565225553553334667333732333222322222324664D7832331123331555444354BBABED26434122222-212111111142112446556956684488888586888888678662-34232------65444544555443444-4444444444545344445666544444444444444444443644444442244444443444411285455544444A9582222522222223335466557455558888899AB66674877433333333355577777778888776666645522221121BB66662222222222311111-111111111111111111112121111113234 5555789-P8766885776554564566655454546778557546554545555674554555545444454454535544445543359878778667695GDE3BQAJEJFDFI78547E7NH4L6**I2EDS4764E6CFD59A86F65HAABECFF89FA67DD8RAEE8AB96k65599PPMS5OO8AHCDB8 * c.112.1.1 Glycerol-3-phosphate (1)-acyltransferase
[ 238] --21126B6664654834223213211233-1-81----11--1--21-2254-1213--27442-1- 639772-3455-1114533-352252333335444455873EDA6752-5526944212222515575763-79932511616241225646-8-----26562849-4--------------51-43134452177798---41C7CA66333446453363478A88A11111-1211112411222--1-4454663655266434-113-563-1--1--------67-11---------1-----1--1--23-22--2-1111--2--31-1----111-------11--1---------------2---------1--8466665683611133-2223211-33-2-341132--31---1-211173222-1111765536313146344444343436-FEGEDGGG55119997527573879452498646443746666666699B77413----------11--11--1--------11-113253---2666587D7775AAA8888B488AB7A54-324632522312191321213332-------21225--331-158372434287A64753A75665513-----------1-----------1-22-14A512163112121-212111-1112-1--21411------23541223333334333-344334333332212322643432222332324233223433121343241113111211-1222---------1--151212211-11112421--2--11--2-1-635354DB84799CA5DDB111111111-321211-11-----348787833322221-143344441--1-1111--------1-1-1-----151--1----12211--1-3513 --11546-642-MOREAFEACEEHFCB88B8777889D9B9BA776DCEEIJIEGI9BBDED855444-64354633-33255555111AMCABAI899BDDFWSW16b9pDHGDMA8765EC8LF6D8U*E3HCK4496C5AE937745A35F988AD66EFSMB4E6779EE81BM3Q1228CXSYuHcN997531D * c.68.1.10 N-acetylglucosaminyltransferase I
[ 239] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------9--------------------------2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1--23---------------------------------------------------------------------------------------------------------------------------------------------------- 9944OSK1XEB189F99A88ABB897988AA8A9897A8A8BA788767898A9779A8B9A8646661665557663765456677787B89D9A766A7B7DBA2E*I***ki*bSNQSYfT*yM*W**x7*g*FPNGmSanYJZPHMYNG*PbRX*JURMcVHAJHJYAFcJ8VTK*FHDYL****8*p9EDHHPY * g.44.1.2 U-box
[ 240] 2241314544445545214233225111422211311111111121121----111122123221-11 47D4911222211143355-56118C555556777746DG454524212322324411--53F377FBB931111111122543334411211311---1423582723222222223322223323334233435554543547985666423444342113534857523222233121145422221314334345342444444333314443243311111111132222222222222222211222---------------------------------------------------------------------1A814555545564735431111513335216775689A364622221--8216455222227CLKP6379C9EB33333333324-EDHCCLEIBA42B67955E864DHDA4539A7BABB98A66666666B78349442232222212222222222222222222234983-7DB9AGKKIJG78886MMLM888839EFRIJKC25EF7B9665C6H6IC678234356343333322478938A29232473443-5765B65895535886F2342244443333333333345345776436226361548888597655746557382-1345212122236335336665655465-6656545656655665665454356653333333333333333B434444441433333333333232222222222281554111213111111222767675525392BBBA88D87A9A94877222222222344472222243333334656633322222134332222--------211-------------------------23655232224622 11--223-522-33243444343243433454423223333332433333435333343343222111122123211-1112222211121332223222313334-4A3F6A664A43343748F293AG4-55734338448344243C44B486543BS4895AACF9E7556363q24594A8GF4EC4453233 * d.15.4.2 2Fe-2S ferredoxin domains from multidomain proteins
[ 241] 33333333334333333333333242233342232222222222222222222233333332223244 21222---------22222-23222222222222332222233322--2---222--2--23222223222------------11111--------1--------321----------------11111111121---------11-111111111------1111-------------------11---111111111211111121111111111111111111111111111111111111111111111111311-11111--11111--------------------------------------------------1--------------1---------------1111111111111111---11-111111111112221122222211111111112-22222222122111111111111122222222222222111111111111-12311111111111--11111111111111111122221111121111111111111231111111123333-133322222222232132211123-------111221-11111111211111-------1-11111-111111111111111111111111111221111121111111111111111111111111-1122211111111211111111111111-11111111111111111112222211111111111111111112111111111211111111111--121111111112221111111111111111111111-1---122222111112332111211111111111111111111111122111111111111--11111111111111111---------------------------11111111112--- FFFEGGECmLFEFEEDEEEFEEEFDEEEEFEEEEEEEEFEEEEFEEEEEEEEEEEEEDDECCEDEEEEAEEEEEEFEDEFEEEEDDEEEENEEEEHEEEEEHEEEQEEMERNsRNSLGHKPMKJNXMWI**R-UOWKPLITDLKKEKIIJKHLPGGFGILIDFKGFHWFGVFEGEFGGD*FGGFGcNiYEQONRIGFFN * d.153.1.4 Proteasome subunits
[ 242] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----IIL-1--145A232322222222222222322222222222233333333222324442211111111112111111222123333423333223121385A-X23z******sjkYo*x**j*o***I***dmnf*mz*lR*kbh*fY*z*v*sKenOdTPP*QTsOjSK--1--1--11----3----33332 * d.15.1.5 Ras-binding domain, RBD
[ 243] -------------------------------------------1------11---------------- 111-------------------------------1----------------------------------------------------------------------2---11111111111111--1---11-1----------1------------------------1-------------------------------------1---------1--------------------------------------------------------------------------------------------------------------------------------------------1--------------2-1-----------21111111111---------------------1----------------1-1---------1--------------1------------------------------1--1--111111111111222111232222121231111111122211111112121---------------------1-1-----------------1------1----------------------------1------------------------------------------------------------------------------------------1---------------------------------------------1111--------------------------------------11---------------------------------11111111111111----113333-----------------------------------------------1-- 869BHCF1iIK777IJELH8AA9ABBDAAAA8AB89BAAA9AAA99IC9CFDGFEGHKEFDE746444135656555245544455656AIEEGMS98BB7I9DCG1E*BgcdljraZSWRWdY**TyR**lA*f*OYWTfYYhWMZRQNeQLiXafVULUSRPPRJUNPVNeTF5dLO*EGFEJYVVrIgWJJ**duN * b.85.7.1 Histone lysine methyltransferases
[ 244] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----J8J----Z-----------------------------------------------------------------------------------------------K5********mjZcp*r**m*k***A*u*nrkm*Pu*zVmkkX*nU*j*ourHd*ECaFIlHIxIIJ62FA-5---32---1-21-217336 * g.3.11.6 Integrin beta EGF-like domains
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g55678H7CH5GC7886437 * d.122.1.2 DNA gyrase/MutL, N-terminal domain
[ 246] ---1----111--1--1--1--1-------1----------------1---------111-------- -------------------------------------1-----------------------------------------------------------------------------------------------------1-----1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-2-1---- 22--KGK-fJN29A77743486864366555556756345556576446776775564668668767637667674737778887876756477476565356FFA-ZM7h**v*vrdYZdfjc**U*Z***F*n*SaXbxSiraRjVTUvaR*blcehHNGRXTNBdKNUJTTN-2135-1-21CHGQ5F998****G * g.50.1.1 FYVE, a phosphatidylinositol-3-phosphate binding domain
[ 247] 33131145444444442333333342245343333333333334333333443333323133213-33 4443644444443454444-443355444445655565BA34453433333344445422656334358733333333223333333333333322233254554433522222222222222233333333333666773335444454445555444454444466554544434434434444533244455555465465565644444456544544443333335734444443444444434434321223232213512221223324442222222334222222222221111111111111322333222234444333333333334443222423124335556445334443333213353444433333344563333334333333333333-3343333343434333333333334533365455445673333333333333333222333332222111111111111122223356335333444464453334444644442486766973355447363454535434333454444444434347A23755444444444456545375655554336423333333323533333333444533665653656876866666776666676767112363432233376655656776666677-775776776776777677699865555565556555655555576657567325555555555552233222222222367674444244334333344444444444A4666676668779A766632211222246667777777777733333333333333335333444411111111112111-1-1111131111111112---24322333333333 1111222-744222433334556544433332333333333333334334436333333333353354434443565456333333844353343C44443434561472227223122112A1V*2H2Ax3-32N1222Y22A3-21213--A13123--22411251-944415558*65665JARF3A887AC876 * d.81.1.1 GAPDH-like
[ 248] --1----1-------11132111-111212----1---11111---1--2422--1--------1-33 34D3B856777555AA977-786697777777678899EB444864123LJ857623B--9752C69HJP711111111111612222557617442--32322B4154111111111111111211321232313333344476T4EF55D22122313332358659K3222223822237643322453433333443334434423445443422454231221124629A7679799889994544321111111111111111111212122111111111122122113233111111111111111111111113213211111112134133222343611333333234333234333211232I655A3333369CCFB739878933333333333-9AC9ABAC4A416334797776374473576366655574444444423344B68111111111111221222222222211112332522222265565453554665554544465645552255496A5345534333835445211211123455768441212435322212423422428898QQ371111111111111111111121122332234236364254454545544544445661-2634511-11144443444444444454-4444444444444444444444443424434444444444444444453444144444444444411342222232226352232222222221222222222222233544443234332422435---------12323333333222246537336667645--51446655111212225231111-----1--2111--111-11111111111114764 21--542-512-5683254334362544444686995556444334-32266CG335533446333332333324332331113334441272114-------768-1l6SCCA9G66357897DA3G6OsE1E8G3849887A91865594584A68822422B13244212B35MPA*555CFNuuS3LG39COEFB * b.47.1.1 Prokaryotic proteases
[ 249] --------------------------------1-----11111---1-----1--------------- 1111111111111111111-11111111111111111152111111111111111111111111111111111111111111111111111111111--1111111111111111111111111111111111111111111111D342222112211111122-12222111111111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11--1111111111111111111111111111111111-11113111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111--111111111111111-111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111-111111-1111111111111111111 ---1945-212-66979454456655466886846845555565556666656546554555225232143443442122255564422388999F3344252423-3E8sxupyqqYTcabiT*nS*T***2*y*VTUTqUdkZRXXTPmXP*XujdkFQRTRQeKnPQcGQV52262131256JUcr6WK2224651 * d.50.1.1 Double-stranded RNA-binding domain (dsRBD)
[ 250] -------------------------------------------------------------------- ---------------------6----------6-----------1---------------422-1--2--------------------11-----------K-AW1-21-----------------6--------6DD11---C-AU9-66i----2--7---5-17K7j-------------------------------------------------------------------------------------------------------------------------------1---------------------------------------8----111---------------1-----------1-g---2-------9--------3-------------22--2-----------2-------8-------6-66--------------------------------------------------------------------------------------------7-----12-----1-----1-----------1-8-----------43------b-4---J--2-32---1---------------1------33--121----2111-5--2--12224116--4------------------------------------------------------------------------------------------------1---------1-5-5------------------------P------212--A691-------------------33337E6----13533232----1---44------------------------------------------------------ ------*----------------------------------------------------------------------------------------------------*2-****o*winjfmwp**g*c***H*w*qhmkzetvTsraYiyhh*oytw*Dl*3UeD2622D8D*6-2-11112----------25D374 * b.1.27.1 CalX-beta domain
[ 251] 2221435465554654423332261123324232623455664443463478528A37FEE3123-22 4951612422213143333-371136333333666645991555243-25512441322233122245653-1111113254524233668618331--1937386A27-------1--11112555566555363333645422B9896655655244934656B9BA33634444634342235455412355555554245555544661354511132111111113422222222222222212222211-11-3212222211112112123---1111111111111111111111111111111112111111-58C7B777778887875777ABA8763542351899732676444556225464333-----465465238779944444343444-5544647622514554453476443542452244444322222222234442B8711-1111122111133112-21222222223385344445444345545557796666624377888612443548998565624346537553233333133B7547C568783558873GAHCBD8A7CACA7F794441344443433222222223545334344255635154444343444544445441-14214------46553524444444444-444444344444444444444433324555555555555555554344443313333333333331113-----4343546344444343344314442222225456747777778796667777734444434451223444443414466455565553333--4944334411111111211---------1-2-1111-1-1111165466767772533 ----222-211-11532231323221233332311132112223333222333523233222--1--2------------------111443265721225333231--5V9A22E443754E3HV2N47u8-59C4534I62SD3B163C*-B3445A97554692A4G633C22644b4348A849B3871-4222- * a.25.1.1 Ferritin
[ 252] 33434287788788875444556497766647335224243426546867656288676663222121 5695444555544344444-45445444444444444564655533442445665443227522533856323331224123434243895724332--263336334311111111111111255565755556999893447476554554355444344455B666645543434444566733433243565666657865677484436678445-6451112113D31111111111111121112241245222224411641413224343444555444344344354343333333323333445222334485-97333444453995886755126334544455884353335637446544455211111553656456556544444444445-87687985583256685766686744444454756654-4444444455534844-------------211-11---11-1-11224433422239787996566666AC7777589BD54544413355534355562445666544334444355665332846453443443374755545455455655213212223341421222224223576657565326375564425466433445343--25555------55445555555555555-55555545745556656645543333353366546664565644553555341533233333323-1213333333335243321121111111111111111133314665666576754454787534443443463324444455536334444434422223174444433111111113-1------1-111-1---3211-----44557534545644 2133545-72335654443344446344433444343444344443444432323444444443433313433443212233443344424243334344343647348685655432332444B5292IP6-544423163442141-25223344475C649442645D34742695v44446KCHK4GA3185563 * c.68.1.6 glucose-1-phosphate thymidylyltransferase
[ 253] 223122111111111121232443344514431-1323212132175B75F92-33334531111-13 --1-6EC8DDFG8E21311--311241----132227G79263668759B74D8465B44781ALC75BW81111111222332-122433313332---11111322-3333323333333332423322232447766224D184455523322322322642498222222222322228553333-39AHHJHJEFHAIFHHIFFDEDDEHIH888FB87777777LL7CCCCCCCDCCCCCC97799812122131115512224111314446665555344666666666665555555555555555333555435C57BBBBACB6D8453338676628492214IG41142334433328542221116646633211347765875555555555E-433334447333CFFA896AD9B88612157OD9EE653333333332443118711111111--1111111111111-11111-11112433345666865666655646666567441112--1112221182422311411-1733333333--2242-7833313435332-212211145222251452366144443111111111132211447A62721122123552324322523455331-3244311-111O7AC5EC8AAF8DFF86-98A6EAF6C89GC888886FFGHHAA99899999999999999E88C999A61DDEDDDDCDDDD115-----------2CAH8886A6334555338334432215762684668588674437991111111114CAAA99999FBF7711------------111322------------8332224------------------AAB32322333331131 -------------------------------------------------------------------------------------------------------------------------------2-----------------------------------1------------------------1---------- * f.22.1.1 ABC transporter involved in vitamin B12 uptake, BtuC
[ 254] 33444344222445443444455565565555655555444457779755555876777773233343 5555544444445455555-555555555555555555555455555555555555555555555555555555555555555545554444444441344444444445555555555555544444444444455555444544444444444444444444444444444444444444444555555565555565555556655566555566555544555555554444444444444434444454444444444444445544444555444444454444444444444444444444444444444444445565655555555566566555554645566555555555555555545435344445444444444444444444444444443414444444444444444444444444444444444444444444444444444444444444444444444444444444444443444444444444454444444444444444444444444444444444444444444454444444444444444465655555555555545555555555555568544444444453454455544445444444344444444444444444444444444414444444444444444444444444444-44344444444444444444444444444444444444444444444444443444444444444334444444444444444444444444344444444444444444444444444444444444444444444444444444444444444444444444444444445445665655555544444-444444444444444444456655555553334 2-11222183311111112111111111111111111111111111111111111111111111111111111111111111111111121111111111111443125243323222212221461324J2-2322132322231222231333322222122122233422254238U6763383DB1564322222 * d.52.3.1 Prokaryotic type KH domain (KH-domain type II)
[ 255] -----111---------1111111--------2-------------1--1-1-2---1---111--11 ------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------11111111111---------------------------------------------------------------------------------------------------------------------------------------------------------------- 669ABCI-N9A1DELAADCBCCAC9C9DB9CACBBA8BAB99BABBCCABBCBDBBBABBB9AAA979899AA8799499A88889AAA9C9AA7AB8A85C9HML2KeMtnncsssVSZSQic**V*S**vB*k*TUWUsPgwaRbaSQpNS*WsgWaGNLPONOBsPSGKHPG7HEF*BCD7EURfmEpFB9APCD9 * a.5.2.1 UBA domain
[ 256] --1-1--2222222232-------4--5112---------------1---31---2-333-3------ 79A1G35444423-44533-34--5433333446662355464657637653578524--1263C24FE7466665552--1511---87D71711---48135A3C76111111111111112223333333438A966---B35FD4663422234544424145595222233322222B882311-18488888877587888728882778866515AB344343-F52222222222222211132352-57-14158811462424424334447545344444444444443222233342222333221333432-382222222A283533-7584-282-5A112212--81-134231251176331-----1557534257556------------56B45866645-55599858886741723142797641-22222222322-4276------------------------------22-2--3233566355723334458323332454443---3337-3---2-5A---524131-111111-1145512221-412121111-4341111-265558714-----------------------11118766173-93A4544447-444254-42-4---5112------58223535665655566-55566656665564554455654411-744667777755756665545666--566666655666-------------3-917222343-22122222----------4C334334345333373331111111111366855555797884299999566------41111111--------2-5----1---1-------31--1----36733526774836 --4466D---11114CA96CHIFEEED4444342223333233354CBBD9BACBCCA867721414532216-6783C61333366899AAA5B896783F5234-791I7K8CC65436657AB583SfG-B8A344383474455217225645767IQ5CA87BCK734734AAC*9A9FEGJULAFK--21--5 * b.71.1.1 alpha-Amylases, C-terminal beta-sheet domain
[ 257] 11211167655666741423322541132233465323555554645547897423111222432-11 437395334444537AC77-77559H767778677767JI232645413532A8965522647368HA9631222112-443911111655314211112322253321--------------133233223322333442221A45635543322224332333344932222222322221211111-24566666568257665732554566634635315555542545555555555555545555222145112-26622553332445341111---22222222222222-------------211222111144446-------5-44233111-223--22241763342233421241-1-315445-11-165KGG434D89BA33333332316-76955D6BD93-A44557B875A9752627AA535898A6666666664222655-----------------------------333A239HD9BECEEDFC999AEEGIEEEE8CDCOAEEB24765444449466EB33631115111111111126661D63523345444614535333654434475821111111211-1-------1221221433341512234443543433335434354-1-413111111177667766777687877-7757878767777776775A9A985478677667778778775B76777761-866666656666111--1---223332962333333133324333444442323542A99959465588644454111-21-1324364444433333443333333311111111331122--------1---------------111--1------111111-1113531 111133--521---2B6846777D9DC555555555566666656644597BBK6634454443564744674547745754444554635264432222312635-37-42322232222222232626K2-2231222222522221221132111348425431112223413333C24365A7BC478224111- * c.36.1.9 Pyruvate oxidase and decarboxylase PP module
[ 258] 33-31353556654554-66654661134344325314544443448952553343245531221--- 36938212222--167766-6C--796666639BCB659B543543323---4361-2--43734496C63--------6ZR565636---------111221242321--------------11133241223288855222463221222111111121111132222------------4424411-3-63333334323333333366263322341--111111131222222222211222211211------1---11-1-------------------------------------------------------166-11111111-1-13--122211--3E--24yr357A-78A11122--43353331111138A6783B6D6B544454443436-99C99B9F9711777667659877B9423749686774844444444944-5A241111111111111111111111111111122443-48748B8888AA8BBBCC9DBCBC6AA9CCCC9149A7696779469778645554571111111112E872CHD46AB6E666D-CB8C95949CEBB699L5AA434367151522222228E677448524346-3-366AB92BJBDC7AAED8JD1--4942111111HBA8BF4EFFEECAGDE-CEEIDCDEEEFEEBFEEE9DDD9942CEDFBDEGEEEDEHECDE978C9BA1-8656788787881112111111111535726669772324334464444423344438889967466888B6761111111112387D344449965644243442221111226-442233--------------------------------------1--111-15521 ------1-----1211112222121212222221112111111111-111131212223111111----1--111------11111---11111111111111122-1--21322121111111111127C1-12111113211111211111111213133151222111132-1111J111-1513C121--3---- * c.81.1.1 Formate dehydrogenase/DMSO reductase, domains 1-3
[ 259] 43-1--7344544546-121333B7344--22-----------------------------1561-11 -134M3-3443435NleJJ-Jb44cuJJJJJThntnebzx3X8Y24321571477648--GLK1KCIJCH9--------3534-----11111122--------1--3---------------------------44477---7842-2224--12----1-1-112241------------77746---8-211111-31221121122112212115342--------2212222222222222121112--1---1----22--------------------111------------------------1--111--------1----------2111--------13----74-256--2------114--C99F-----84ODQ345B5CG944443444436-BBABBDAFA4H1LCCK875B7A67AI39476975667366366666651112253-----------------------------1AJWC13LD8HBHJRRDBDGGABBI7GGGG6CVEaSbaO236A685B76JBE9IK258-1-3442222222212B562XEJ-----1-----322-6-2--32539D45---11-------1--------1-----22-4746387-2544446B444463B6456--1121-------32741214445455445-454544453444555455546511572665356655464644633435234--233343323343---3-----4434-9733--------1-11--1EFGFFAG455L3PONQDMAJFGHGBBCAB1111111112111222222222234366466344------1-665477----------1------------------------------------1-- ----322-744----41433245113311212111---1----1--43233444332321112---1----------------------1211112----2211---15-6-11-252312--23121-6D--2-4232-222-12-413--3222--7123-41351222132311--1---21142731-3323238 * e.6.1.1 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
[ 260] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------1-------------------------x******kqnknuk**i*p***1***fmkn*omy*Woqpbrjd*q*rppDQRYeVNNjNM***K5-----------11----------- * a.123.1.1 Nuclear receptor ligand-binding domain
[ 261] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1d-11--11-1------------------------------------------------------------------------------1---------1--821*******xkpf**z**m*v***7***erzk*ow*tV*uob*hW***y**JMPfaXMLeLOfLiZJ-----------------------1 * b.55.1.2 Phosphotyrosine-binding domain (PTB)
[ 262] 552-53214534435282444321C44A5472--11-243321--132-1412-5756434432---- -212D213335--122233-36223E333331899A25AC364A45321331333121--56716457643211142221--4-----2222-2----------1113---------------1-------1-1-33445--174343622346442333234444454313--11131--12125633-332445356763465656842222557333432322222296422222222222222221114522231-33355112211-3152222222222233444445345332222222222222522111222216123444445434325222333314837432-451-2431-31111132---22221111131MLM225B7996FFEFFEEDDEV-33D23A37Ln3-pkkckej*ysrmF7-11EMOJEINTHE111111117222113811111111---------------------4---3-6FCA8EGHGEG9BBB9HHQREECC7AIDN96A7--777A3766A7MDFT334131184223333332333212A22583--5225211--1123-3233461221-1-1112-1-----------1--1175B1512132922222122223324223221--1212------6AHE2957887977777-8777778867866776776BCCDE3346766666666566666D44445462-8CDCEEEDEEEE11-1-----222231D9M444765123224336222221112243A9999CGEBABAC7DEE111111111-4555777776687722333333332222---22211111111111122422122-22323222222112431113413433454-3-- -------------1------------------------------------------------------------------------------------------------------------------------------------------------3----1------2--1-111-----111--4---------- * b.40.6.3 ABC-transporter additional domain
[ 263] -----------------------29222277H--1--------9B-2C34H97--------------2 347-2-1-------244----4--21-----133335162-3-6B3--11--123-------412-6B651---------31222335-----2-----4661485A85------------------34--1991A99452114-724266112CC------49279571------------511-----34111111111-1211111111211111-1522222222254-------------------------------------1--1--------------------------------------------------71-6111-11-112-3---111--2--2-11-334321-------1---617CBB531212639EE886JGCEI11111111112-URLUP9Pd162-8GGG7798F8786563544143365A2--------84421PAH------------------------------7627-621-483334663232228B33431226B26681-887M8A67999N3256N65KDGD-------2239RX7GD165E81JBFGB-C7EA5675A12214949I2552444423---------LDA7D1-ID6AB4H595IBDGEF8A8HDDCE88ECDA---5D88------4485-453333333332-1333323324133333333-1-76-2222221222222222225231---3--633333333333--15111117666A4DAA----1----------3333311-1-77CEDCCGGGDEEFGCHEI111113111G1436BAABA462555579699789------V-ED4466----------2-------------------------111--------D-1 -1--432-11----47843411221132211-1---1------22266225896467445552-1112--11111-1-111----11--11181212124631346-4h26IDDAEA8764998IC6I8PmI1GAN7857B899859774A45EA589E31184421333E1156-565o33388NBCH6O8ABB9D9I * d.110.3.6 Flavin-binding PAS domain
[ 264] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------1-1-----------------------------------1--------------------------------------1------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1------------------------------------1----------------------------------------------------------------------------------------------1------------ ICDEQRC-vLI7HIMDCEAAEEEDDBCFFBEDEEDFAECDDBDEDDCDDEFEFFADFBBDDDFCCFFE9CFEDCEEGDGFCCCCABBBCBMDCFHFCDFE9JDEBE4IeXqisgdqZPLMJLXP*lMuN**k2lV*KNLLoPQcNLSLJGVLNiLWVaXTXNpMMOEqMGZEOOOBOIG*FFEGGaamtDgRKMUNPNL * h.1.15.1 SNARE fusion complex
[ 265] ------------13B--------1---------------------121--211--1--1--------- 3883L546556646A9844-49338B444446CABBOOMQ3FCGGC7D598389A36733INA3SANUWS9533354422D6411112111111111--2322234213---------------1111111111132344434B3412333221-1-----122142521------------767451-1389CECEEFGJ8DFGEJEH8CCABDCI579B856ABBBD6LJ4444344444444444436354C26634464DD117795543558874532333993323322322322222222222223232223332-ABBIBBBDEDC7B75ECC2331E521-33322FHC2123-22-2---11421844D1221222323527314216666666665B-56637765A87-7AAED8BC8A9848669B68A57758922222222621323751111111111---1----1------11111696E277876CDEFCDA8777EE85999979GDH888F12CF7486DBE7B993777323283111111137128649363313326223143432254332336912212112122111211111112211368892BD54663466556685D76B5546A56---3325------59332745445555554-45555555554555555547662223577766A77777A8669335422251-444444344343---711111365317B35222535-43342-216687A2314-55ACED9C9AACACDC755---------234485555559456A7324223331111--2444------------1------2-------------1----------------C731 -------------2------------------------------------------------------------------------------------------------------------------------------------------------------------6-----------------8-----1---- * a.6.1.3 DNA-binding N-terminal domain of transcription activators
[ 266] -----------------------------2-------12222172134-211---------------- 3CC-J2-54442223CC99-9G--B8999997FCDC999C396A7722433-43512---857-R9CJKF7-------2-2161----2211-311----3-234653433333333333333232244237443WYZYb---u-D8AB77655334454557A318CB9233322232332112----114B4444444524445445577BA544264462399999843111111111111111122121----------------------111--------------------------------------------23213222222222222112222223112326332433421151132-1-1-22111-----559B97134222711111111111-835333264321533423243423374245256555373222222221223-C35-----------------------------3126212434244454563333547B33332343448571-2226453374534387B6314851111111121467288453882DF997354453242645A64*3531---111111---------3232311764465433446555555565554545666--24567------24224232222222122-2222222222222222222455333332222222222222222522222221-412233323333---111111444463A58111222111111222645552422267666678767777797773221222225554677777565BA23778775551111--M5PPLKLL1112122233--------------------------32-22222222321 --11454121--22534322222222222132222222222223333344443633313222333333-2332334413422222333446242253323222977-28-A9EA8CK9675897CF4I5b*J-OEF8867G58D93A545E65K6CCAH5CG487B469AE58212322Q122544BAH3D4349AJG5 * c.13.2.1 Anti-sigma factor antagonist SpoIIaa
[ 267] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2211118-512-4461233222223222233333332222-2222222222222222222221111-11-11-1111-1112211122235223233212321222-9k2*jkt***fXhghsl**e*Z***8*x*mbZf*UvwQZljejrYa*n*mjqKKNSyu*WwYgVGL*G184Cc897FCCAFH3K7A6YZSSp * b.34.9.1 Tudor domain
[ 268] 22112111111111111111112111111111111111111111111122221211111111111111 4443433333332223322-222223222222222222233235343333344444241155332214333333343444353534543333331332133343434341333333313333333333333333344444333434554554555533343355555455453344444445333555525343777677767777766544557774445544666666677444544444444445555424544443543443344454443233555454464456666666666433344333234443355533365866655555556565555767756555754434445435554446625544466654443444444344444444444444444415445444444435444554565554465433333333334444444443444544221222222211444444344444411122444444444444445455555444455555554455555555466666676666656476666444444454456654444444444444453544354455357543334343322143223333333434344553467535566555567445554145566213333333333343332554444444444-44444444444444444454443333434444444444444445444344442544454444555223333333333325456333324333333333333433355334445444545255544443333333334555644444554445656565555333333445534333333233343433234-343332244434323433364255353334554 44224321B442333333333333333332333332332333333333333333333333233233331341233242223333224443633335333333344723K34232151222322357151CG2-422122132121-23131112-112421224252542512427547*88834A9BE3895564436 * d.66.1.2 Ribosomal protein S4
[ 269] -------------------------------------------------------------------- 1-------------------------------------------------------------------------------------------------------14-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--11111-1-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- ----1-------------------------------------------------------------------------------------------------1-------********qbam*v**f*r***2***VoXi*t***S*rsg*bU*qhQX*687LhziX*ro*DHP7------------------------ * b.1.1.3 C2 set domains
[ 270] ------------------------1112231-------------1----1-1--------------22 13-39123113-1164445-48--694444459787C9JE24261113----555331--A65-4448631-111------1------1111-111---4123321431111111111111111-1--11111-1---------14212221111111111111122221111111111111----------2111111111111111211111111---22-1------1111111111111111111112-1-----1----------1--11------1---1--1111111111--------------1----------1-11------12-1-----221---11---------1----------1-1-43221111112295A2-22223222222221224165945C4813-25332226222685711123632231442222222262223211-------------------------------24314A78887796898889668F888858C9C7C8B227767637366535934753345344444442219AB1-112--1--1111----1-----334346-------------------------1-2266746465766765663675555659957A1-1141511111143444335444544455-455544454544444544566643334434434434444444454433334214555555555551123-----344436557222213111111111777775635492BBCB8C98ACBDA7566311111111246544444456655224242233322221-1-442222----------1-------------------------1-111-1------2 2211464-NCA-33HFDHDHDEFIPGH889ABAAC7A776866989D9BEJKKMFMHBEDFDDAC77B4B76C9CAC68A5JKIBQ476BEAD6B8D9B8579A5913W6E88668D6897798GF7E9P*B-E9F6977BA9A6888A8B95D9BB786CB4C6A2653C56C48569t6777BIDWOHIEE8GCGEF * c.25.1.1 Reductases
[ 271] ---------11--1----------1215-2-1---12-323331-13-12476-322223-------- --2-1---------1-------------------------------------------------1-------------------------1----------1-1-11-11------1312222---1--------232-3---2-114263-1---2111-12-122533--1-------1--------------------------------------------------1-----------------------------------1-----------------------------------------------------------------------------------------2--1-----------122---------------1---------------------1-----1-------------------------------------------------------12--21--2-1---------------------------11-11--11111----------------------1------------------------22-2--11--22-----111-----1-43--------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-----------------------------------------1--1-----------------------------------------------------111122--------------------------------------2----------- CE9CQMG-ZDCBEEG9CBBEDBBCBDCDCCECCBBCEACACCAEDECCDBDBACDD9AACAEDBEAIE4DEABECFB7EBEFCEFCCDFDKDCEAKFCBHBCBGEL6GOMWOVMTQgNLSKTXShhTnN**d8lc*QRPLaRVjSLUPILaPHkPZaNUGUkJMPPLTEFlGNPP8CED*DGDFDVHZUBeMCFGEJHC * a.118.1.10 Clathrin adaptor core protein
[ 272] 112-2322222222222234433122211122--2112111111111122111121233311112--1 1451712244411222211-11112311111-33332433141331312111233111--32224146786111112111932112111112-111---1344473341---------------4111122112266678111629476776353322232235238775121111131111222--2211323333333333333331411113332223221------24--------------------112-22-11112211221-1111221111111121122222222222122211111111122211-2221132211111122131321111115131-433-1441--4222---11112315411322222327563333333333333333334-554454437532633365544544353334554444454--------222--3323333333322333333333333333323324444-35544777676333334444565435945454522776344448554644354343531111111333334283234533443332332232362443493252221211111112111111112112333344455333776666666666686686654-4343422-22245344445556566665-555666667656655555744433446545455555555554545555555423444444444443334111113533536432223432222233331111111111337777765664444344532222322233334333335455356555553333333223133434422222222523----------1---------1----3333333333-622 3322A88-C53-675555555545545555555555555545555545455555455555554442222421444222222555453335835536333332377C-795MMVEDPB79679C8JR6MB**C-IBR9867E9BCC7A965B68F8C88EBEHGDCA8T8CFEJDB3475*33357FEPN5N68866568 * d.43.2.1 Band 7/SPFH domain
[ 273] 2212127777777777148373677777727766666666666666667566661111111667-166 2237A38444438388866-682288777778888888883ABA32223111333223--88B8A9A9A9811111111226622213662626661112423383413111111111111112782732222776777732432778777787776666663779777766666666666666277111384444444344444444434434444888832266666684333333333333333444431111111111111661111111111111111111111111111111111111111211116111111111277777777777777677777777721116677789772168774221661214444111116886622388888777777777772C7677677282-888888988899673329988888A896666666632226838----------111111111111111----12933333335999A999888899998888789994444243374E74488838344734348422433333334871662626666666626667666C722222626211111111111111-111122122225384336132343333643333343433A41-1247211111263336232222222222-22222222222222222227774477366666666666666664222222221932233333333221511111124262736221212111111111222222223333888877888888848881111111112233522222346441144444333222222624477771111111152111111-111111111111111111111166111112222 1111113-52211142222222222222232222222222222222222222221322222222322222222222222223342322224222293332212333116121111122111111211417I3-315111112121111111211111121211111-1114112-4446Q4444454562432333335 * c.90.1.1 Tetrapyrrole methylase
[ 274] --1------------2---1------------------------2-1---251--2-1--------F- -4912112222111-------1---1------1111---1-2-311-1-----1111---21--4-3--3----------1-------64B--7-----1123242123--------------------------233-2-----3333331-1--1--2--12161425----------1-1-----------------------------------1-1---------1-------------------------11---1-------------------------------------1111111111111------------1213333333-3---------1-1---12---12----1----1------5----------11-1--------------------11--111---1-2---1-111-------11-------1---------------1-------------------------------------211-1--1-224444221-333212321--1-----111---21--2-------11----------1---232------11----34----2--42468F-1--1--1111-2---------1-----------51-1---------1----21---11---1-----------------------------------------------------------------------------------------------1-----------2-----------------------1---11----11--1111----1---------11111-----111----1----111------11221111111--111-1--------------------------11121-1----112 12--1---226111--1212-113231----------------------323443-11-111--------11--------1-----------11----------2112l*******znphffkk*tl*l**r4ze*jijipclrQUoggW*kW*m*nshQ**X*spZnad**Pb911111131-1121-31-63222-7 * b.68.5.1 YWTD domain
[ 275] 221---6311111112-------3333G-G64--5752----1m*4A*-7***1-122------91-- 13E-L----------------------------111-3---317225-26--------111133141-451-----11---1---6--524--133---4MI9H**E9k--------------1---------A--4455---7-21--11--2-----------2----------------572------1-333334231222222-1----222---1---57798516-------------------------------11----------1-------------------------------------------------1-11111111117----2221-4--2--627--------1---23--1-4--------------------------------------11--------------------14-2------1-F--------------1----------------------------------------------4--------1--------4---1--11121-------1-----------------------2J-2-----------C7H123F--6536F171------------------------1--22-A-D51516B6555C449864553F47N---11--------311----------------------------------1-1-----1111111111111-11-----------11111111111---7---------5-7----------------------------B----------------------------332555555655811--------------1-----------------1-------------------------12-11------3-1 ----1-6---------------------------------------------13-----------------------------------------------------B-7zVeb*kSOOILPWOkbIVM**sATp*EUNIbOUWPBQPP8mB9*MuTfVI924NP428544--K5--------1----------1---2 * b.1.3.1 PKD domain
[ 276] EC347FEGSQQQPOSUF3GF676R857D8IB5232393333339318M346454KFDOf8A434A342 E9H542-1---2--123lk-l81122mimlm15546412235B655181121121111--32223232231----422116313274---11-1--2--2--3---E7211111111111111211O46E-2J21166AD---41FSKOCGt1278612321PK1YDMH2111121112112135DD12-831111111111111112211111121331212111111111111111111111111111111-1-11-1--1111111121---111--------1-----------------------------------71212222222212111222221112111-32H24A3HA427J34582--2A2L33-11--1671545228GA8911--1-11117-371323B3554-C4489CJIE87K47--233852113118888888834751166------------44AB15645-45------1275-1221289AAC951222775222223296876A61423575763AD735D22E312111121-111H33G43121C-16--4-111-282822M111122281511-------11-1-------11-32EE-2253--221-13111121111111111-1--2C26C------1-11--1-------11-----211-1-1---------2232-2412--21-11-11222214---1-----2--------2-1--8133233112211221444----222123--------1---4211312113211122753---------1---1111111-1-122737322225131--32BB7775--------E---------------------------162--11----5-- 1122334131225463333222222232222223222333333222333333332332333345555435535556656555554544456535555454573453246277555865344363864739f6286845544247435544542C4465664445564644945753333F3335463373541212222 * c.120.1.1 PIN domain
[ 277] 67335876666667574488A8785445344567787788977888A998988956546454545288 4B66834333333344566-654455566565855554977AAB52321111344322116792525988311111122155477655777625441113435475527333333343444442665767357554226622274779B66A5499757666998BA997565545665554363778744222222222232222223522222222222112------5422222222222222222221--------------------------1111---1---1111-----------------------------784864344444454567745545473375887779AA765A94357431787455722222466665676587744444444444-76769778464254452234433264442238555532466666666466553322222222222111111112111111111114452354444555555544446598454444567345212333265443443514354424352232222223545-888865AA9B99638989998DC6776586E6555555555544444444545677665564324332435444337664547635543-2423722122244432423333333333-33433333333333333333343366343434344334343344333333333333333342333--224344433335353533322232222222234444342342333233433445434344333333333244344444433333433333333322222244444433--------511-------------------------56677657877742 11--1-1-311133422221222221222222222222222222222222222223122222222122-1122222222222221222224222222222222333-2B321211111113111213235C2-31311211-12-1122113111211312112212111A11426BA9*8788696A9267655334A * c.1.28.1 Biotin synthase
[ 278] 1112111111111111111111121111112111111-122122321311111-13111221112-11 2222322222221221133-3111113333312222111116431124111-112111--21111111113----211122211111122341122---1421121112---------------1111111111111111---3232242211111112111121144321111111111111111111-1247777766867886872233337752223-2211111162422222222222222333331------1--111-1------1--11---12-----1111-----------------------312----44311222222212123221222313-212221322362-2423214121121111-11211121112111221111111111111-12113141112-11123131212111111213211132211111111121211111111111111--------------------21111222223222322222233222222232532243124332223125442332332212222222221-3414114122632223331353254543555563222111222222222223222324222113323312232132222213322312232221-12222------23361222222222222-2222222222222222222233222423333333333333333211222321-222242222252---21111122111-322422111111123221222222232232323211351212112232-1--11--22222433532222222323222232222--5-11------------1----------------------------111--1---1221 9999DDB-ZCC7ABA9AA8AAAAABAAAAAACA998A98BA9AA9989AAA9AAA9AAAAAAA999AA59A9999BB7CBA999A9A9AAEAA9A9BAAA9G9AB96ASJOLLDGINHHGGJDDWLHPFp*L-FGVAJEEGGEFGDEGGGELEPGGDEDAGCDEBCBB9FUCDFB9ABD*BA9BAKHOO9JDCGFDDEF * c.111.1.2 Ubiquitin activating enzymes (UBA)
[ 279] --------------1--------45585355411122222222443453343224333333-337211 1111111111111111111-11111111111111111131111111111111111111111111111111111111111111111111111112111--1112121111---------------11111112111322114441112222331111111111112232221111111111111111111111123233233233323311111122311131111111112111111111111111-11111111111111111111111111111111111-1111111111111111111111111111111111111111112111111111111133111111111121111111111111111111411-111111111112111111112111111111111-11111111121133322222222211111111111111111111111111112-11111111111111111111111111111111111111111111111111111111111111111111111111111111212111111111121111111111111111311111111111111211112111111111111111111111111111111112111112112111111111211222111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111-111111111111111111111111111111111111121111111111111111111111111111111211111111111111111111111111111111112111111111111111--1111111111111111111----1-1111111111-11111---11111111112112 66337774SZD8A9747458666757655455555555454555556576668656525555544444444545455455444444555687766854445549AC35XUfUYYVUFGKQNMKXQVIxL**O-hVxGLJHWKKXO9HJRKQGCXIUFMTFGlEa*DFJFFoEGZF8BCB*99958bJXb5O*79EEHEH * c.32.1.1 Tubulin, GTPase domain
[ 280] 11-1--22111111-22211211123322322111111111111111112222111111111111-23 69E3322222211212244-43444244444412223243223211-13331111-221122111211211-------11212475453312-2224--321236244412222222221111233133223173444843334465594424344335454345876771212111421217634411-256555555565555566336566656236354323333345-11111111111111211-1214122131-12233333323222221111222222222222222222222222212222211---11121--313232332131221111115241-341133454432654443121-46F577845655649898657757655555555555-877898865932955589A8876677678644777736666666666255549432222233333221212223212222333223366245535799B97567778867888886A9777872355566444657544466276545333333355635355331234396445278748666688A9HD552335133333423222222222-21663324363653155555444555545345553-2655511-11154555454554555555-5455555555555554555454553434444444444444444444533444244444444444422452121143446743443434224343344433343322222233333222333434222---------34554444445455555545444444444117333887722222222441-------------------------33332433448D84 1111----732-3473121122222222222222212212122122312222252222232251212112112232222211123245322211222221322567-3J-8ACEDe765358A6JA2G7SyA-B8D4637A686749554845A8B7AA46255363335334454554b311437JNB2C617888A9 * b.36.1.4 HtrA-like serine proteases
[ 281] 11-1--6765565674-312211441132233354322222222423324564411-----2421-11 437395335543536AD77-76559G777878666666GI233545413532A8965622636368F99631232112-3219111115442131-1112322253321--------------132222222222333441111A45635543322224332333344932222222322221211111-23566666568277664733554566634635315555542545555555555555545555222145112-26622553332445341112---22222222222222-------------221222111122136-------5-42133111-122--2122176232121221112--1-114333-11-154GFF324B679833333332316-76955C6BC83-844557B775996425269A42368686666666654322343-----------------------------3336237FBA9BACCBBA8888CCEFCCCC69BAK89BA24655333338355CB33431113111111111125431B22412334333512214112443323474621111111211-1-------1111221433341412234443543433335434354-1-412111111177667766777687877-7757878767777776775A9A984578677667778778775B76777761-866666656666111--1---423332862333333133324333333332323552A99959464588633344111-21-1324364444433333332222222211111111331122--------1---------------111--1-------11--1-1112431 111133--521---2B6746777EADD555555555566656656644597BBJ5645454444564744694547744754444454635264432222312635-37-4232234122112124242CJ2-4231312222511221221142112337415421112223513333C24365B6AC4792331111 * c.36.1.5 Pyruvate oxidase and decarboxylase Pyr module
[ 282] -------------------------------------------------------------------- KCP--------------------------------------------------------------------------------75789RSRJ-R68---7K8DBVBQ9G--------------58799A79B99A----------2122221111111123211352241121121131111-4244226-1--------------------------------------2--------------------------------------------------------------------------------------------12-7-------2-321222----22--1--1144222132-1-----32K6FI77B222229697D8497676311111111112-334243341161322442453323396871141111221DDDDDDDD7KKD695511111111111112221321111111111258HB8BBA4ERRUTUOJFGIIPOOSLMMKBKRLRHPLW35JJMADBHIVFD7G4FKIBKDHCC1122222A7B7CF87J576B444755719E7CBCDCFDDBEF96DA5433323323444444444A648BDG5579568686537666366B8885578985--28828------55592653676455754-6554555456665443445867AC4335654555554445445612753341-633333333333--2733322BEEFG7627222212112112112999A97922397IKKKIKKGAJIIHB9EG33333333394549666667BB77GEC9C99677111121A3DD7777111111112-----------------------------22-22222AF44 ---------------1----------------------------------------------------------------------------------------------------------------------------------------------3----4---------21-------------F-----8---- * f.5.1.1 Outer membrane efflux proteins (OEP)
[ 283] -------------------------------------------------------------------- --3-------------------------------------------------------------1-----1-------------------------1-----1---1-1--------------b----------------------------------------------------------------------------------------1------------2411-----------------------1----------1---------------------------------------------------------------------------------------------1----------------3------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-----------1-------------------------------------1------------------1---------------------------------------------------1------------111-----1-----------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1 1133UiA-E5I3JFS87B6DAA877AA8A86766A6A9788885468896886A34565987795568394536665255588557443Z*I7***5685YF3b*N-8Q**SSKQSFOGLGHSL*eHbL**S3dQlOLLJTJMSQCHOIFQFFUJMILPFGCJYQ*FUJfL6Vf88qj8J322MLn***A*e36FFHHO * c.10.1.3 Cyclin A/CDK2-associated p19, Skp2
[ 284] 22--211111111221111111-2B4432295443--2211123523211332-11--1212221--- 4232123866854443388-8K33D4888885D78C6557232445466221749234112363526364122222223364324323343313-1-111537455444111111111111113212311-121-34433111442557334223311311135429A72111111111111273331-1323555555655556555433333556352434563343334433252222333323243336343554233444225564332244531121112222222222222222222222222222543333333255453334443444248822323324333321744322232242332335136337-----7734B9395473433342443449-6942C775967-5556549944585D34292655552233333333353112525------------------------------2425133333633433444446634444435674467914CD4354C978355295A3443642222222262437313313244534452424223224234365234232232332233332333324-1358444333232242322223242262222722---2316------34333333333333433-3433333324333333333435333324343444444434333333222231-333333333333---31111-456773212111111-11111-11322332234345556856554467645552111-21-14333333333333333211211111----1122432222--------3151111-----1--------2---11111311121113564 5757533-F43676433564434434444432344445342544456455689924545545243331-311325221322333333124D431231211132-3932GF6C5A99HB8C992998B76I*41D8KC9A85757999DC58C7IBA78745B74277112F67462556v75487D95Q5AF67ES8FB * b.82.7.1 Calcium ATPase, transduction domain A
[ 285] ----1-1333333332-1-----5-------1-----------13--1--311-11-1111233--1- 1243K2143342318DD66-8A3398666666A99A8GJE2744A3433352756446--7672J6HHKK311111111-143--1-------------29344B5623---------------46467A437577567822271936711334---11---22-686981--2121-1212A5322111424HHHHGFHJ6GEIGFD435447IID22274252442437743333333333333334455142236312214311541-1124111111----1111--1111-1-1-------------3111111111-345544442335421533-211211112-22-4411-11-1-114--3-8-35894-----33D6A1--5845444444443434-55654346175-A786988C9789D162433433442252222222233211123-----------------------------223942364236BBC85833336657444527C99958A1187848-32478551122212123111111111135872231-11-2211--3322112--6526C9-21-1--------1--------1-1--1132-422214112444334422232253337---2312------111112-1221111311-211211112122111111-2211-22-1-11-11---1-1-116--11111--211111111111---------254413313--------------111221-4-33325555497A4445538A61----1---13322333232355555454552332222--1-443443--------2-2---21-413211222215224----3132214111-2-4 3333C84-6111566CBIB78B5C8BD5424327673555266222DBBPIMSMBE9E7576545114333245422222154655212BH6B6N32-2336766313R3L79BC457464475A84E6Uf8-C7D554376966267657547555A79A76B6B-532C646D5647852296OGJb8TG76D87E9 * c.69.1.7 Proline iminopeptidase-like
[ 286] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2244IR5-51-3DDZ5799S6876856BBHA9C77579899BA987LR99AEHY8BFT9BAA222222-22222232222222222FCB*7D7ACL989S5C2GL*3D*CHymfxjTSRRRMZT**LyU**o6xc*PUSRhPUkSFVTLNfJLkKcSWTBITCCAfFYCIQEPK52DB5E644F8gKHNADG36****- * b.34.13.2 Chromo domain
[ 287] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- DD89FE9-P683HDF7A9A99AAAAAAAAA99AAA9BAAAAAAAAA98AAAAAAB9A9AAAAAABABA2AACABACB4CBB9AAAAAAADHEACDHCCCB5GCDDI3HKDrbk*ggZQQRSTTS**OdK**p6rS*NQQNXLPaLOQPPQZSPvPVYTOSnjPNLjL*NRQAMRI8GGE*FIEILhTngAkMEEKNKJ9 * a.118.1.14 MIF4G domain-like
[ 288] ------------------------------1-77511111111-11-------5-------------- 5546555545556555455-55556555555556565566555754464555555544555545545556554444555454544444555546554--56655666563333333444444455555555555566667---7746655564444444333665466654444444444444334455464545556466457544554555564544496554444545455555555555555566676555555565555544555555555554444344444444444544444444444444444444444444467666555555555554555665456646436588655557556656454441444544444444444444444444444444444-444444444444444444444444444544454544444444444444444454454------22444444345444444444445545466566555555555555555555555555666657665767778776866665555575565555686556655554444444444444443456555556454444444444444444444444444555555557655555555555555555555554-4555514-43455555555555555555-55555555555555555555555555555545555555555455555555554555555555555444544444555555554555555555555555555555655555555555555555555557777677775555555555555555555555555555544546655664445444444--------------------------46444454445556 -----------------------1-11----------------------------------------------------------------------------------------------------------------------------------------1---------31--246-----7123-14--2---- * c.72.2.1 MurCDEF
[ 289] 33---25333333335-233332-33322134111---11111------1111--------122---2 233-541433333243122-24--23222222333355CA23-1211322217553631147725435661---------1-31111122231122---36775866471111111111111112323222223233333---332222222--222222222214334222222222222246444--1624555554565556555364444555244352222222255244444444444444544481-1-22-2---11111111----------1111-22-----------1111111111111---------1122211111111-1-3-22-21-252-1411--11111--3--1131-214-4444511111448563235565822222222224-4464574345A15654546556556554868933334772222222222213576-----------------------------142562576497667679666665AB666656A8B989B139986557788979622411116333333321127855-4143521232221575483574A95A6742343112222222222222221211111552674647839999979899999988999--2221211111144342453444333333-4333333333434333334323443343323333333333333433333331-433333323333---433333333338557222232222212332667766756465BBAB989A88788555621111111124556444335565577444343331111--226566AA--------111-------------------------11111-1---1335 2---555-A32-22535656778988755564655553331334538744557332324343933333-31133311111333333--16B2568544444265F8-984aFKACNB8978698IG7HAX*J2LDH5998998B679596871B69879AGG6U621A472698F4683H555656249688239CGF4 * d.38.1.1 4HBT-like
[ 290] -------------------------------------------11----------------------- ---------------------------------------------------------------------------------------------------------1----------------------------------------1-111--------------1--2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111----------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------111111111----------------------------------------------------------------------------------------- ------2----------------------------------------------------------------------------------------------------1P-*******dchdkih**h*i**x-*n*Zjed*gmxcYghdbkhT*hygkuMVe***UQnSO****--3--1---1--------------D * b.96.1.1 Nicotinic receptor ligand binding domain-like
[ 291] ------------------1-----1-----1------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----DD6-211-JIP3476566574856655565444545445656778889CF6896677754544434345543323444554433443344344244443LJI-G5*V**t*u*gdb*fbi**V*Y***4*m*YVbVvbexcRicYKrYT*c*YdiRRiKOLJ9KGFPKbHK-----------121611-2GOKMD * a.91.1.1 Regulator of G-protein signaling, RGS
[ 292] 22222233333333333233333333333333223344333332222222222322222222223222 3451521222222242222-221122222222233345442223211221112222221122212235332111111112223322222222221111122122232321111111111111111111112211323422111431111111111111111111111111111111111111222222221111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112432333333332321333233322223222333333332332223231313233333222233233223333343333333333413343333433323334334333664324322422322322222222222222333222222221122111111111111122221222223332344454444444444444443455444532333333333433333333233334334333334333413333332232222255454454343444223221221111111111111113221244333334323323344423444433444333211343211122244333434444444444-44444444444444444444443344444444444444444444444444431434344534444221322222222232332444434333323223331333322233444444423444442221221122122333333333333333333333343333322312223221111111111111111-111111111111111111111111111112321 57337661LE9576876666666878666666666666667666666666666656666666566565366554676366566665777698666666666768CG389IUBLEHFA86E97G7CE7N6V*A1FJL4DA4i79FC67776D64D7C7898HN798A9JA58GBB97787*87777HDZL6C8778B887 * b.44.1.1 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
[ 293] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----9AI-----224--------------------------------------------------------------------------------------------H14o******jheakni**d*f***C*z*Zlih*dp*iWpihW*aV*k*rrnRg*aTQRNvHQjNfUK-11181111141-2-23--22221 * a.11.2.1 Second domain of FERM
[ 294] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----57--321-11-------------111111--------------------------------------------------------------------------1-8****z**bfYWbmi**T*m***6***NcVY*XV*rNfbhblNS*WTOu*746J7G33858822Y2----------2-----2------- * g.43.1.1 B-box zinc-binding domain
[ 295] 11-1-1-111111111-122111132231132--11111111124225213532111111111121-- 3362E212--1131A5444-47--5A4444436666B7C7-5487212111-535332--653291EKDD3----2211-1-211222334315111---2143F35291111111--------21111111--12223311151835355----1--22-1-1172352------------21231--13-3998998963988688615434685232344521111194422222232222222422341131211111122112112--2--1--1-1---31111111111111-------------211111111--3-4544444441421211-2222212-1111---1---12-1111-1213-5B777-----547871-33315-33443442446-BA79A77D8F5-8CC8A6BJGAADA4-3447A524459D222222225634422511111111-----------------1111-1-51-26546IQQRQKECDDBIINMGGGG5ITJI7E94-1887138217336A4191121273-------3-4-42431-2342354225-5451225132343392632221111111-1-------1111133432456727323455432464456455546--11113------37874834664444544-64454354546553444447A6567534444444444444444734344444-433333332333---4-1--12222-4EA8---1-1--------1556772514441DDCDCINKFFGEG8B8913322332312228343245524555464662331111--224433441111111111211112-1-11121111112211----1--------2311 1111442-321122533AA58BA57444444444442444443444655D8AHC7677433321413223211113512211113256836438B522311-1222-2F67794388433133294-53GX4-74A2322733531331-42253664645234411211622833542T22235ACIG7GA22B4543 * c.23.16.2 DJ-1/PfpI
[ 296] -------------------------------------------------------------------- -------1----------------------------------------------------------1-------------------------------------------------------------1---1----------------11---11--1------------1---1-1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------1------1-1---1------------------------------------------------------------------------------------------------------------1-----------11-------------------------1---------------------------------------------------1---1--------------------------------------------11--------1---------1--------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------- *23345A-K9213342221422222222222222212212122222332223281122233312222221312212212222222232337225436242-4411--CF4***r**qbWXRYqb**V*a***8*w*YfUe*djzjUkedZ*VS*evdkbPWlOSXLE*EJlTVRL-35271---1444727111695B4 * a.39.1.7 EF-hand modules in multidomain proteins
[ 297] 22--1464988868962812211321132314554577555554743529F9B944445346342212 3471G11111111123311-11--151111111221243352-516621221743317113137B787B4333333334676632211665414332--344547464A11111111111111111-122111312225422226232233213224444452322445534222115222344211985211555555554555565423321555221B411555554732222222222222222224243111211513331122111111333111111113311111111111111111111111111111111116C789EEDEEEE7D64D5586658556484453HL7A7A46BA77A5261644422511111446643225763666666646669-54534744BA21C66866A879975343137A5255546444444442445354211111111111111111111111111111321914354435556567666655677777554793433224464422223224322324444222222223227321K793145629332257454573323321557114-1----111221-11--32124225424344262264444424444444454461-2344311111132742224444444444-4434433444444444444555767533333333333333332224322234132222222221211222222222224282323222211211222222222222224544444433344433333211212211244543444444444222222232222222153--3311111111115-411-11-1-11---11111--11--1194215B5454414 2111555-2-1-11133515674766532332365543132332323246447642-2-345-1111--211322-1--1-22222111513324331211332112447B8656785647566FB4B4PwB-C8A44377487737534745B6447834456863956624663135H2334455592543241214 * c.55.1.5 BadF/BadG/BcrA/BcrD-like
[ 298] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------1----------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------1--------1----------------------------------------------------------------------------11--------------------------1------------------------------1---------------1------------------------------------------------1------------1--------------------------------1-----1------------------------------1-----1-1--1-------------------------------------------------------------------------1-------------------1--1----------------1-------------11---------------------------------------------------- -2--J6P-T-1-5-KN1-2N---1121116--1--16---1--1-3Re-----2--2aF-99D771---b12---Ai155-15I-21-B*-L12KW2-2O2LJ4B*--2-29LI3-1---2121211721R32211-21-212U-111-18-151-Z7E3m1D*Gd*2--2J-m3-3T----151*rZq173--****- * e.8.1.2 Reverse transcriptase
[ 299] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------1-111--------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------11-1-11-1----------------------------------------------------------------------------------------- ------3----------------------------------------------------------------------------------------------------1Z-*******gejeiig**i*i**y-*n*aphd*dmycWidebjeR*iyhfoIad***TIiPM****--33-2---2----------4222A * f.36.1.1 Neurotransmitter-gated ion-channel transmembrane pore
[ 300] 1--1321222231113133314126554234241-111-11--5723333N85-4244552-122-12 19L3C1113311--875BB-B844H8CBCCCA847478CC-I8E4462332-43714311A78-G4B9AB5-11111-23--63-2232143-422-1-3537282683-1111111111111234533344495977CA333H6M97F785854423-133143825BF12-43--316113341-32-437DDDDDADE4FBEBAA575542DFB2125131333333D8522111121111211311121-1-22-11-21122321-1221424111112224312222211221111111111111132211122211398766677772A24599443451434332348641111822--233362-63443-1---447566662553745545554554-64846D39485-G447AC9ECDCA622443241524324444444446551673122111111211122443244131111----314124312153314452222--353333143-43121--1114-2512235313133---4------1-13-24-162644334771122894A5463599B8HK6A61441-1--11-1111111171458331113432-1234444442211335-22454--13115------323-142122112221--1111221221122111111-2-233252122222222122222--12332-2-4111111112121-2133333363331823---11--1------233333231324177472473623353522233221223223231111163411658353255411111114665565--------5-1----1--1-----------------31--221444A423 3311946-932-128899536A3F9A91232228F56221122222GA7978DE35824564224-13221132232-11212331542663944412323348D9-2KAS1434312-4122-521328I3-424--232333233123321221-34N86CE66--12222355897L223B6D658969DE5476B * c.66.1.43 CAC2371-like
[ 301] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------w*****tWZdagqe**V*W***1***TZXb*bhsfQgaWPpWW*drkhkDOSudbSJkNMz**J4------------------------ * g.39.1.2 Nuclear receptor
[ 302] 332221----------21321212-2223123------------2-1E12322--3-2341-----42 -25-A11111111135455-5433445455533647316333133813-111526514--ED41M6AEBG1---------3132-1--1122-2-----1522252543---------------1--1---116147779-1-E3374222911----11-232-59878----1--4----M7A24--1-264444475537447675999775753235854-----1941--1111111---11------111231---11---22----1--1-22242233--222211132312222222222222133--1121234139121241281735223675C32-1533521-2314441432325352-42111-----3-23312233233------------422-13-233--11121-252132242114231111112111111111---2--1------------------------------2322-2211-1111223222211134333-31113233--334413--132--21232---1---1111123431-G14------111---1321535-11332AD-41--2-112----------------1--21-3236233-B55749338862B53423B--32111-------2-11-1--------1-------1---1------------11132-----1--1-------3---------3-------------2D-----11112-511111-1-3----1-1-232221----112342435-2222313221--------1-112111113311156BBDBA99C3333--1-11---------------------4--1-6-113-1--111133-221-1----2-4 3213BB4-612235C7BD854747837776789EHGKHHHHJJ56655JhSQXVMKQJ9688G44334145445434244455555444434BC2533333E4GRN25WMoGADHDC99A7AAIFGAGCO*H1IFO7AAADAAB769BA9A98DBEAAB5BEHL8AAH66P8CH5-FS6S222OFCLFcAWrF79C79G * c.41.1.1 Subtilases
[ 303] 1112111111111111111111111--12--------------1------112--------1--1--- -12-2---------11111-1211121111112111-111-21-1----11-------------21-2321-------1-13---1111112-211---1211151-1-------------------11111111------1311-211111----1-111----122---1-----1----42311--1112224243331333333-1222232311113--2222224321111111111111131121211-22-----11--22111--12231111---2--11112211311-------------211---1111-11221111122111-1111---11111112----111----------221131112-----112222221---2----------1-11214211211-211123144321-13122211111-111111111111111322------------------1-----------1131133321222222111112234222212232111111211121112211111121111211111111111111--112--------1--1-2---1211114611-1---1111---1--------1111211121631111622222112322122221321-1221211-11122221213553323533-6243333333633444344232111113232333333343323131111111121111111111111122332211111153222212221111122121111112222222233222244332222111111111211111111111122221111111111111122----------------1-------------------------11111-1111-1-- BBA987E1*VSF88A6A9A89AABAA999A9A999A9969999989A999AAACA9999988BAAA9A8ABBA9AGD9EEAAAABAABBBJBABBECAA9799KHP58pBOMdIOKOHCGBDDGIIDTFl*J-PEbEEFEHFEFDCDEFCDFBOECGDEHJLDAA9AS88FVtC86EDF*CBBCBTIYh9bGCFMGGJS * d.159.1.3 Protein serine/threonine phosphatase
[ 304] 2332-1427545666243455573522653472--2121231244228-36541222-222112--12 26L2722-111-2317633-4211B4454446635463891EDD463111--11-113--98--16995C3----------23213-21121-11----3112282431---------1-----114434-25229CCBG111G2G64854534441221122116364522212312111241344-1-22177767786268687833--2166621-1211---1--72---------1----------1---1--11-1-------------11-21--112-1------------------------2----------1-14----1111221122----1-12-131-2551341--1-122-11134-466513322768F95555547622222222227-ABEA9B9837924335C83A7B2456344243544524333333333355439A422232333-1111122111111111---1-1462-222214444434435544847685596548457245623343532454252A323353--11---336366373535551BA6455A2798A95496782E57-2221-----113-------2131364234317136113333355724436455344---3547------52222123445343422-4222224234443222224434232323233444434433334322333322-255555455353--12-----333334732---131-----1---111111132-36666667732345412551333344333222233333341221212222221111111A2445543--------31--------------------1------2---312223D-- 11--993-C6612347AA97BJAFJDG8696568B67877887868EB9CDDHG39DAA5764521222332422222313332241317C9A755222458688716n7N7794833533342633519J71625223242242225514231228157854D4A6573854857BAGxAA958ICCG8AECIADBBK * c.66.1.41 UbiE/COQ5-like
[ 305] 22-1--2433333332--111112211111231111111111111111111111-----------111 36D5522422332384566-64229F66666788788EHE28375231144264422211355237B54431111111-131511111--------1-----112313111111111-11111111111111111444331111523322232211111211121334531211111211114342211151133333433133333331422133322123122222113711111111111111111111412122121111122221111132223332222122111111111112322322232232122331222311-2111111111112-111---11211211112211111211211111171165571111122LLM224E6AF444554542436189BA576D5B81C44A55567765L91724555455356545555558442222211111122111111111111111111111235D11AHGBAB7BABD5777799FC88784AA9D7CH8143324664474B3C8441111111111111111214424341122111111111111112144345822111111111111111111111211122112232-131411111-111111-11-1-2-111332------1133--2---1-11----------------------113122-1-----------------4----------11111111111----11111333325427---------------444441212213545439583355429791111111112111-----------1132222111----11111111221111111111-----1-11111111111111111111112112111221- 11--222-732---3JJTIILJHOMNPGGCDEECCCEGIHIGGDCBJGEZObhsGFFD5888865244662363A53244455576234DO7J5754447437222-3F4c5663442323222454535N4-437334342253233413317467554752C459D56FBAA12754b3437AFJEOM7B4122224 * c.117.1.1 Amidase signature (AS) enzymes
[ 306] -------------------------11-----332------------------3-------------- 5545544444444444444-44445444444445454455444654464444444444444444444445444444444444444444555545554--47765668564444444444444455555555555555566---7645555554544444444555555554444444444447444444464444646466446544554444464544485554444445444444444444444454454444444454444444444444444444444444444444444444444444444444444444444444448756555555555554554665455445445466644557445654444441444544444444444444455544444444444-444444444444444444445444444544454544444444444444444454444------11444444444444444444445545477677555555555555555555555555777756775666667666866665555565565555686556655554444444444444443456555555454444444444444444444444444555555557555555555555555555555554-4555514-43455555555555555555-55555555555555555555555555555545555555555455555555554555555555555444544444555555564555555555555555555555655555555555555555555556666566665555555555555555555555555555544545555554445444444--------------------------46444444445558 -----------------------1-11------------------------------------------------------------------------------------------------------------------------------------------------1-21-1159111117121-16--2---- * c.59.1.1 MurCDEF C-terminal domain
[ 307] 11111211111111111------2111111111111111111111111111113---111111111-- 3443545555555555555-554455555555555585663333466555545555551145445674445655555543432211214444332331158675433432222222222222244434444444444433---5365444444444555555544444455555555555555555533344333333333333333333333333344433342333333333333333333333333333333433433333344333333333333333333333333333333233333333333333344333333333333333333333333333333433343343344333333333343243333555555445333333333333355554555555-44444444554255555555555544554232222222222222222222234641111111111112222224221221111134434444444444444444444444444444444444444444445444444444444444443454444444445635334444444443333343444444454342212222222212111111132325336636676456664444555444454554551123423------66666656666665665-66666666666666666666666644566666666666666666666666641555555555555113433333333345345444444434344444444444444435333344443444444444453443543566555555656664444444444333332325533332222222242321213-323133233333223333312111222121425 4522762-K86122122221111111111-11111111-11111111111111111111111222222-22221222122221222-11---2----------333-3R352334523333333213423G3-3262231333342334332233333233233-41233-32355DGEaBA977756A2689C7I458 * c.116.1.1 SpoU-like RNA 2'-O ribose methyltransferase
[ 308] ----------------1-------83441155123111233225537754998--------11-1-76 1556P-12111222VOLBB-BN33LRCCCCCHRQVQLKQX3T9WAF2424225A7321--AAA1H8NIOO6122222212328-1-114541-422---1313484632------------------22---13-444771-165954344233222222224211AA61121211121211326----1122555543652554545-3321235422-42121111117311111112111111-21111-212332121233--321-112-3332221111--------------1111111111111111------1-34556754565-3-1355----61311-3-1-34111---11----1523-383351111123A885449756522222222224-66866B796D716775C96CBA67643443B6434564511111111411144361111111111---------------1-1125614136663667776754555447555535866587522444653556484722653133621111111--135445824231234313-897252633887948324244233333224222222233-13463314454351123333422322212222141-1-112------22442222222222222-22222222222222222223334323333333433333333335222222221322222222222111-1111123221182533312133333311321222132223177664565455442233---------3222222222433454344454354211111-2221122--------1-------------2-------------2-----1---2323 11--223-2111529899B5889AAAA6756665567757676666899AACAB789776565463453444545554445444453336A596866664365342-2F574543322343332622324G3-3342333333331315432-32423343-13123715421323644O33498A8JH9C66333425 * b.45.1.1 PNP-oxidase like
[ 309] --1-1------------1-----11--111111111112222322111222221---1--21112--- 3342942344443363343-4322354344435444764424433543333452422611547474898833333333223323332244454534-113423453534--------------122222222332333441113332333343333334333353333433333333333335442233223344444444544444434554344522344332222226335555555555555544444221132221212222321223432221111111222433333333331111111111111222222222325234666556635366224333322113443244232334234342134436544454444435453343446344554555555-444446477A53699966A665556455365644443673333333334442465---11111----1111112111111----2568635656555667756665446377774577645452233633433537654444322254333333346433436732255433666255545444433335423453444444444544444444455433665454654564444454544444444433-11444311111154653435445555555-45556555554555555575455566666776676666767766443555441644354434454113423222444444446222222222222224333632456455667678677777557884343353333444A555557769733444444443333224222222211111111211-------1-----------------44544333333454 11--445-31111122331245364662222222223333333222432345572322312221212321222232212221111222423232212222111213-497A37A5583444233AE3D3BO41637533263373333434235154478A91H4212572338F2554P2223656583545488776 * c.1.6.1 Alanine racemase-like, N-terminal domain
[ 310] -------------------------------------------------------------------- 38C3a21111121-47877-7711756766657798899A4JCQ5A1255525AA314--KFB2S7GEDP5132222224881--12256-3-3------1-12913141111111111111111-211-26121CABGH528E-65535441242324434234336631111112111-154211---126999998AA6889B884986458AE2219243333334BC33333333333333354463B2347744324335555533212221676312223344444454444-1111111121111532213233-457C7779A8A8784G8822426643623A2-B822-214213231112741A66621---47L8A3-13725811211111111-567559574F118556B7ALF998663348975465365--------42235756----------222-2212-11-221----1-442258758CEGCHBC8885AABD8A8939ICE6BAF1168971832C7-4D1445232243-1-----5125473232121-1-2112-3223237443343551-A45523333332122232225534944842314C2635B5775C9C88877ADE6AI---1212------864535B7995766577-987774579795956765798935773B9DCBDDCADBBDBCBB5556664318776877568881146111111111-1738232-1112222----3334323--111212273DB355742232111111121-7GFF77777B9K8A86759558871-----7-222222--------1-2----------------1-1------1121322222161- -------------1------------------------------------------------------------------------------------------------------------------------------------------------1----1-1----------------------6-----4---- * a.4.6.1 PhoB-like
[ 311] 22646642444444446466464E444424444424444444466466222-24AAAAAAA444A-66 246474-2222---22222-2222262222222424448C486546444222444444--44C264AA86A2222222----444333444--222-222222222242222222222222224333333333334444423-46224222422--------42224422------------22244--24222222222222222222244222222224222------42222222222222222422224----------------------------------------------------------------------44---------2-2-2-----------2--2266-2B--246-------26242242222223E6A42C4486822222222222-88A66966684242224266444648222444222284A--------422-4844222222222222222222222222222222242224KCCI64444464444448B44442444E4KGG2422268468C4468B2464222482333333446C442QOC44C6-6A884-868272A24226244K8--22222222----------34553224422422224444444444444444444442222444------8444464888B8BBB88-8788ACB8788B78A6AA84464444664446466666666464446444642444444444444222222222222262464222222-222122222222224222246666242224442222222222222224444444444444444444444442222225-222222------------------------------------2---2-2---4222 44--444-93263335555566665645545555555555455555555567473355555532222212222222212222122223335353333333345435-43687D54664445544885C4El6-7374444544563454444474646A79A4544684A866555332T22233747G5723443333 * c.23.4.1 Succinyl-CoA synthetase domains
[ 312] 33-3-575666655673557686D64443553B57453766778867B4ADA8532211252428-11 4667732222222233344-44224544444335554497447224132111123511--444544557531111111117647765655434533---2634464526111111111111111ABAAA889A9754487---7724553321244333221343433422431222421223323332243433333333333333342334333333432221111113211111111111111111111----11---------11---------1111----11-----------11111111111111111111111-74266666666465547735536323271188GGDJA33AIC3311112393222211111443431122422322222222222-444447483321222234323322451225434444222222222224223362511211111111111111111111111111122221222245555656555588685555256744534333432223363435543682225622222221125672MYHBLGIGEGBCF1HEG8G7E47BA7A579O422425544313433333334454543966334734358A99849888886769886--2647A-1-11174667636666666676-6657676666667666667777664468878888888888888666666662187777777777711131111123337344644453544443444422222222226455555554455554444522224222376666666645666111111111111112273334444--------212-------------------------22322222234523 11--111-311-1111111111111111111111111111111-1-21111111111-1111111111112111111-11111111111111111121111-1212-11-1242211111-12111131161-11211111111--11111111-1211-2311111211211112222c2212212851361122121 * a.1.2.1 Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
[ 313] 1112-13333333333-333222233333333222222222222222223332212111113332-33 3343544566744444433-3433353333334445358933433453444465643411657554654332333333112242322233332422-1234233333331-1-11-1111111122233322233333332223333333333333333333333333333333333333335433322124477777777567778764555477623453333333336333333333333333333333122344322224433442324322222221-11222122112211211111111111111222322222232-45222222222222442221222334222344423143233333112433444433224247333334433355555554545-55555645B5335664566547557A333456443744533333333544333342223333322111111111111111221232343234436655556455554445777765565475724444335346576574333222434544444333344334243452545543333333344443434264374355554533333333333223334443333333344444342222332223443-3333322122254655444444444444-4444744444444444445565774464444444444444444544444444344444444444422332222233333344544444444444444455555353447388886776466665665322222222343354444444434334444444433332222443333---1-1112-1----1---1--------11------22222342333325 12--324-3-1-3342544433345443333433333333333333333437697533333333433334336343323335344334536353343333333444-3526293245454522433454FZ6-8362224333523325635633952566136336833B24753334i4443383394633253335 * a.127.1.1 L-aspartase/fumarase
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n6-77G4455865533566565386435537347412522613231213Q12221649C4571355358 * d.54.1.1 Enolase N-terminal domain-like
[ 315] -------------------------------------------------------------------- 68D11------------11-1---1-111111------1114243--11----1------1-1131-1113------------31322EEI6-9661--AHD8AGQE5D11111111111111132556333643---------1411--1112----1---1--22125-1-----1----1-1----6112112122222222222112212222112121111111121------------------------------------------------------------------------------------------13123222222221213221111111--111112112111113111116863276672111147CDA6758999A55555554556-76A66A795A738667797A9866665968B8CACC7AA5555555587776CBB1111111111111111111111111111117686447748JEEDFHCBCCCEEIFFFFF8EIAD8B9724657C98978687F367F86577523111114457AL88D356B639C8784D9G8A9A6977A7IW74745434444452322222224543433CC26BD95876AB8A89BDCABA99FAA9B1-56A5811-11167434555777577786-775676666777656555577643853474555455455555574346666327B9ABBA9ACBA112633333766635I694443443222134335677656698AAEEFEEDDGHEEFGEABB333333333ACEHF88888KKEBB8889A9889944441146DDAAAA2222222263--------------------------1-121111114226 ------------------------------------------------------------------------------------------------------------1------------------1------------------------------1----1-1-------3--------1-----1-----4---5 * d.79.7.1 OmpA-like
[ 316] 221122----------2244422231123-12--13323333311-1-22333-3333333222212- 2442522233322244444-444444444444444444662667442222222222242233424335534222222212235434444433143341-334243434433333333333333554344434334444771122467857776655555555775588875555555555553334433332444444343347545355774433434343113333536532223221233322321122111113112112122111322212121211121111111121111111333311221221121111111124333422453334433552223335215215644355357334341255445333524324357996575755523333333335154745A4689529555A77889873344423586772542222222253343574222222222233323333332333321572454531311333343432222444733334444634342264522323654343243422334333333335465343344344234363143323544376659934233222222222222222222222244444545754465565666545455565464313444522322245544554AA7475955-B558468678A985554565444444444545646545574456474555643444444444444334644444444443744545445444215444333333343354777A55357766644333333333334444744444666556744444444433322945555552222222244--------------------------12121212223633 22--22222---1131111111111111111111111111111-1111111111111111111----------1---------------12111111111222111-1M221111211-1--111-112161-11111--11111-11111-1-1--111111311-111512459DA7*89ADDLFOV1BE9A3111A * c.14.1.1 Clp protease, ClpP subunit
[ 317] -------1----------------63363332-11-----------11-3211--------------1 275-K222443111EC999-9E22FRBBABAAMEGGCBJF2D898C122441312437--553-D7FBFF3---------1161------------1--13-31F2251--------------14333323212286647---73DDAEAA85799444664776ADBC94542333442333111-----1322222-212121--2421-241-2---1---1--1---1111111111111111------1-----1-1-----11-----1----------22-111112-1111-------------1---11-------23----------11----21-1--------32-------------1-2-2A445-1--195HBB2-255657---------12-57865A5B1B6-56639739EB77481421A423234453333333354316372111-1--111---1211--1-1--1----165B71133137BDED86333344CC555526DA897CA-3554365445293F2331-33331-------21113113-2-----------22--11121435367--2-------------------1------32-151324213322333433312233122---2-11-----------2-------------------------------112112311-1-1-11-11-1--11------------------------4111113333-4452111214-221112214555522-133178472685A24231323----------2324222224222255444454532222---1773366--------1--------1----1---------------1---1----1-1 21--112-4-1-112LMKE6AA7JDIG66A7895956656576364DECVGIPT99GA6666424-32-11131632143145334---JKEMBE52133568455-688REE66A946666468A6E6Ur9-99D4365A55977835455676987AHBA1977CDAEE75BI2874n7479CQMSXCOQ65B9H76 * c.69.1.11 Epoxide hydrolase
[ 318] ------------------------------------------------------------------33 3663333333333333333-3333333333333333333336633333333333333333333666633333333333333333333333333333---3333333333--------------2333333333336336633633333366333333333333333663333333333333333333--3333333333633333333333333333333333333333333333333333333333333333333333333333333333333333336333333363333333333333336333333333333333333363363333333363639933333334333333336333363363333333333333333333-3333333633333333333333-33333333363333333333333333333333333333333333333333333363363333333---3----3---213333333333333333333333333333333333333333333333333333333333333333333333333333336333393333333333333663333333333433333333333333333333333363366333333333333333333333333333333333-333663--33333333333336333633-333333633336333333333333333333333333333333333333333333333333333333333333333333633333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333336---33-333333333333333333333333333333333 3333333-C6R33333333333363623333333333323313333313333332333333333333333663333665633333333333333333333343336-3589LZFFFO36B666695586Ij6-86B36369636366663638966866-9R33653S637ILB33333y63333D8EL4FC-68333F * d.130.1.1 S-adenosylmethionine synthetase
[ 319] 22312212111111123222222231222223434121111112232222212111111111112143 3343333333333333344-4333434444433333333533334433333335433333443333333432333333333333333333333333---344545343311111111111111133333433233444443334333333333344333333343444543333333433334443343334444444354554444444444445444555445555555654444444444444444444554455444546645555446567664445555555444444444445555555555555555555555446554555555545444444545455443453333434454334444356334333333333333343333333533333333333-33333333333333333333333333333334333333333333333233333333333333323---------------222243333333333444444333333333333333543343423334333333334433333333333333333333333453333333333333434333354333443453333333332333333333333333333333333343333333443333333333333-333333--33355554545556566545-557556555556555555655455554656666666666666655545544335434444444441234333333333335433334433443433333332333455334444343343333333333333333333334444444333353444444443333334433333322222222533-1--2-433441233343324422244454444443534 22--313-6213223123333333333333333342243333333323343443333222322322121321312444442222232322412222222311433611636672345353343386354EK416472432434334446-332A345423431313-221332123324L4421395575784253434 * c.26.1.3 Adenylyltransferase
[ 320] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----hcN-----EBJ12336643656522333333333333333233333665646653333---------------------------3232455----121332-PSGct*qw*mcWSLZdW*mP*Y**n3*o*JcZTqXduUIZZTRjUI*dsZcmQ**LVaPQ*SkVDDmW-463o---12ISfW3V8637877A * d.109.1.1 Gelsolin-like
[ 321] -----------------------32222222311122222222221222232213333333-2272-- 1111111111111111111-11111111111111111111111111111111111111111111111111111112111111111111111111111--1111111111---------------11111112111222112221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111211111111111121111111111111111111411-111111111112111111112111111111111-11111111121132222222222211111111111111111111111111112-11121111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111211111111111112411112111111111111111111111111111111113111111112111111111211222111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1111111111111111111----1-11111--111-11-11---1111111111-111 77336664PWA78A7374475556465444444444444444454554555575354444444333333334243443543333334445667556544445489B34VTaRWVRREFGKMKJXNVHqK**R-aQuDIIDTJIQM8HHOHPFCZISDKTEEiCa*CGHAEeEHUE7AB8*77746XFWc4M*69EDDCG * d.79.2.1 Tubulin, C-terminal domain
[ 322] 11-1-16765566674-312211441132233243222222221312213453311-----2421-11 4381942233324258A55-55338E555557555554EF2225343-242197854511635257E98621222111-211911111223112--1112211152321---------------32222222222333441111A44524432211113221222334821111111211111211111-235666665682776647335545676346352-5555542535555555555555545555222145112-26622553331345341111---22222222222222-------------211222111122135-------5-42133111-112--2122176222121221112--1-114333-11-144CCC2149358533333332316-66755B59973-744357B775A96415268A42367676666666654322333-----------------------------3336237DA8899BBA997777BBDEAAAA68A8I89B824654433239355B93343111311111111112533-A32412334333512214112443323463621111111111-1-------1111221433341412233443533333334423343-1-312111111167665665666576766-6646767656666665664989873367566556667667664B65666651-85555554555511---1---223332862222222-111-3222333332323542A99959464588633334111-21-1324363333323333332222222211111111331122------------------------111--1-------11--1-111222- 111133--31----2A6846777D9DC555555555565666656644597ABI6645454444564744674547746754444554635264432222312635-24-42322222222221241527I2-22322222-2521221221142112348416331112223412221812144B5BB476223111- * c.31.1.3 Pyruvate oxidase and decarboxylase, middle domain
[ 323] 112132-11111111-11222118JEGFJJBA343432222216335856BA924443433---1--- 1223545233321144433-34116333333543334444333455433223434482--5535416468321111221-1154-721LLJK4I762--52-A4232I2--------------111---22--26BAAFC333627C789953244444455665A65614433444443445665511-235445455554555555364425555413544311111123322222122222222222223422232322255443223143-22255532234554444444444433333333333335224452222164127757777374343348863754563514442824461621122651492--224444-16--2--1----444422244-5-1-41-3--6-9--4424424446643466A78686676611111111-----454--------11-------------------21422136622111111311111153111111115887411111313223121112544-1113333333311-67267JBB6H747C335426364A39235566876323411111132222222224455711DC4692775676766757667665767687--45547------97668959999999999-99599999999999999999998844699999999999999999999999932988898888999--3822--222-23757466646624444655611311111223455555433C5655B3334422244243888955555898772224244222222244B322112211111111541----1-1111111111111111---32222231221974 ------2---1------------------------------------------------------------------------------------------------1-3-----------------------------------------------------1------2----2E54S4644-624---24421--4 * d.286.1.1 TrkA C-terminal domain-like
[ 324] 55324622222222335333333122224232111111111111111111321122243332112-11 334-322222112122244-6122335555532222324436441223122211131311453221257411111111321111111144441344---3223252254222222223333331111211111212223311142523422311112222112222223611111121111234344222333555454754555565453333666533334333333353233333333333333222224422332122312222322111133355543335454444444444455555555566455655555553444342222222526423336745332452422222222112233343323231222-----225445223223222222222223-45545544551-4333344334431222234333333332222222224412222----------1------------------122221222113443334333333334444143333433-1222222222222421-1111132111111123312142333232235222-334434463344335142222322222232333333322332337523112124335465338433537855C61-2211122-22264445545445555544-44555554554543454454444533455555655565656556344444421454555535555111-22222222221222333333233333333222222211-422222122122222322244444444415765555555746622111111111111--1433333354312111232----2-2122321222222121232354333534313-2 12--224-62253315532SFSBVaVRBB9A68332132334375621QpEJPg99EN532522222212222112222222222222245253331111353332-35399G69C44354344BB464FX5-64A44446557344532756C6444422768934G6576745133141112144A855322A4752 * c.56.2.1 Purine and uridine phosphorylases
[ 325] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ -----------------------------------------------------------------1111--------11-1------------------------------e*kI*UZSYZhnO**Y*b**l-***UTUZfUD*zFRuVv*WJiaQNKd-----------------------------1---------- * d.19.1.1 MHC antigen-recognition domain
[ 326] 222222222222222222222232--------222-------------22122222222222222222 3333333333333333333-33333333333333333333333333332333333333333333333333323333333223233333222222222222222222222222222222222222222222222223333333323333322233333333323232333323222223222233322332233333333333333333333333333333333333333333222222222222222222223----------------1-----22222222222222222222222-2222222222222222222222239322222222232333332333223223223333333333333333233333333322222333333333333333333333333-33333333333333333333333333333333333333333333333333333332222222212333333333333333222223333333333333333333333333333333333333323333333332233323333333333333333333333322232222222222333333333333333322222222222222222222222222333333333333333333333333333333332-3333322222233333333333233333-3323333333333333333333333333333113111333333333333333233333333333322333333333333333333333333333333333333333333333333333333333333333333333233333333333333333333333333332232222222222222222222222---------------------22222222222332 44466582D563666666655555555554655555466555555545666564666666566556665556665454554444556664766666666648666646B5F9A995686766668A5C6KmA1ACC577896676587669769567786A67F687B788C8C7A689*9AA6778CG6EBABA8872 * d.14.1.4 Ribonuclease PH domain 1-like
[ 327] 1111111111111111111211114223323211122111111222121111111111111---1-22 1122745555555546644-45336644444556665544233634232332333233--555263444541111111----3213222223-2--1--11122432521111111111111112334344333433333---3166667755555323333456544543333333333332111111-212111111111111112111111111111111111111131122222222222221222321-1-11-1---11111111111-11111111111111111111111111111111211111111111111---------------1-------------------------------2--3235554122245555765456555777777677771666767664762AAA89AA99ABB5644345787885544444444465544555111111111111222222222222211113555444444423323242222222522222223333542222244222232342224332343333333334434311-2-3333332241222222222332335233222233333213111111122333444444333446244444444444444444332-3443611122233753333323333333-3323333333333333333555445433333333333333333433333333243333333333322223333311113253833334333332333333333332224333334343344445444111111111333343333333333333333333322222221445555111----------------------------------3111121112411 --21433-83514335567455666643333333333333333333446677776657687732322442532324444443332222235353634443433334-5P2DDHAC8A7787679A7496Ph7-98D67878687677587766C9A87C6A56B586B67H4665CA8D*DECAAMEJP8DCBE7355A * e.7.1.1 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
[ 328] -------------------------------------------------------------------- 2241E5445561-1DEELL-LDCCXALKLLLFGDCD85671T9Q1111111121111311SK11v2ZuCh22222222-111211111111111111--11111611131111111111111111111111111111122111O2373355A11111111112119CBV311111111111111111111117111111114111111111154112111311111111141111111111111111111111-111111-1-1111111111111112221111132111111111111111111111111111111111111132111111111181441111112--1111111211111111111211124111111111443111122411111111111111-33734333221123361121112226131312222222311111111122112121111111111111111111111111111111232112212233438A88854423AAAA3A3221211112332221132224423111111111111112221122432111331111113435227142212TD11111111111111111111111111122111-143211443333533333342333341-11111111---71521211226155222-2212112123222111111213527331211111111111111111111211123333323323211112222222232181111111111111111122222122114322233622112222635211111111111141111111311222222211111111111111111--------1-1-------------------------11111111111511 1145px2-311-324BFWCeJMSjvkb666768NREEGDGFFF777PLJTMKHKEDbWHBBB444445-44244444-344444444442C4F4533333457533-3D3R54443-21--222212323B3-324122-222511222-3115263222222871C537C64571222H222291133R211167875 * c.19.1.1 FabD-like
[ 329] 33-3-342445443444-66654761134144214214444433538963433243233431221--- 23628112222--166655-5B--695555529ABA759A443633213---4361-1--43624485B63--------6YP434525-----------11--1323-1--------------11133231222266655222443221222111111121111122222------------33144---3-63333332323333333366263322341--111111131222222222211222211211------1---11-1-------------------------------------------------------144-1----------13---222----1B--22vq2345-589---11--3334222-----268567265B5A433333332324-88A88A8D85--66656654876696312637565663722222222722-4913-----------------------------11332-3874796676887888AA7AAAAA5987ABCC9-39A6575667358668645544451111111--1D861CGB46A85B666D-8A7C84823A979585F499323244-4-311111114B455448524346-3-466AA92BIBCB7AADD8JD1--2931------FAA89C4EFFEEC9EDE-CEEFDCDEEEEEEBEEEE9DDD9942CEDFBDEGEEEDEHECDD978A9AA1-865677777777--11---------5356255585523233244544444233344288888664666669656---------1377D344449965644243442221111-16-331111--------------------------------------1-------33-- -------------1----1111-1-1-11-------1--------------1-1-1111---------------------------------------------------------------------------------------------------1----3---------------------1--3-----1---- * b.52.2.2 Formate dehydrogenase/DMSO reductase, C-terminal domain
[ 330] -----------------------11--1111-1-----111112-1211352411212221111--11 3242412433322243344-44223443444344445564234554533222565322223243437552321112111223422222444413442--333434443422222222222222355344333334111112221134554432233222224443344532222222222224342211233333333536333343343445433333335332222224533333322333333333333223223232223233332233323233332222222333333333331222222222222222222222233233444444444434333333234322433333333333333323122224122122222234533243323233333333334-4325343434226324345444332222223422223222222222223321332222222332211111111111111122221223222333222242232222224333342332343542322236433622252442222232222222234422344456333434443243354355533344634211111111-111111111142112223331222333423333433345443333432-2422222122222222222222222222-2222222222222222222333324322222222222222222222222222222222222222222224443334334234322222222222222233333342322333336533322233433222222222233344335344453444545444422223331222222--------11311112--12-11----12--11---22122222225433 2223C94-6222665788525655477552545344254423455455557777676565665555552555455452555555554554848444989444683424C357A77AB99625G5JF6I9i*J-THI3785C77A87CA64D7484964753336322424966A36648T77686C7CE5889865654 * c.97.1.2 Deoxycytidylate deaminase-like
[ 331] 55342477777777773544533465566766444555555553444444555566657565773-44 4472334333337234444-4222634444462222633333333342333233332322323453334333333333312322222233431322-1135344435331111111111--11122222222223666661224223233332222222222232222332222322222233323333232422222223222222233333322233325216666663425555555555555465556656466465446655675665755565555666566555555555553333444444434655555555533253333333323233332222241122224233333233333333125312211111111122111111111111111111112-22222223232311111111121112112121111111111111111111122111111111111---------------111112211111111111111133331114444442122121111111321111111211111222111111111122111432211121221113212211111111136112212233323222222222222222113443122133333434343333343443351-3111121122243334333333333333-332333333333322332344433453444444444444444433333333315333333333432221333333333312113333231333332331111--1111121111211111111111132232333232333333333323322222222222222112433323333333333423-----------1------1---11122322323332423 11--667-D753665555555556555554555565475555555555555555555565555554552446645662665555555554A55456756456566635L4A7665786536756A86B5CW6-86825549667326664542B7644346547544565759752746n67565CCFL5ED5867968 * d.14.1.5 GHMP Kinase, N-terminal domain
[ 332] 11213122222222222333333211121111111112111112213321222123242222222122 4433323222232234433-3433433333334333433321232332222222232211223432431123222333322313233333333333312333333333422222222222222322222222222333333343333333332233222222333233332222222222224434422333344444434344444433333344433223333333333243333333333333233333333433433334433333333334443333333444333333333333333333333333433333333324355444444444333333343633334343233433232222332333323111211111112212111122111111111112-11111111111222223223222312111121122221111111111111122111111111111111111111111111111111211133332222222222222222222222222222222222222222222322232222333333333222333333333333333333333333343443433342212222222222222222222222223333233333343333333333343343333-2122233333333333334444445444-44444444444444444444443333333333333333333333333333433333333333333333322222333322322333433333334543222222222232333333333333333332222222222444344444434333343433444333322223333332122222222333333-333333333333334333333333232222433 6733765-H553456777777677777776667777677777766656676566557577776666564666666764776555666666C4756565654466663687A69485B5556556884A5DU5167A5545845765544555485654558B45545866D67756545m7665586DC6976596664 * b.40.4.1 Anticodon-binding domain
[ 333] 11----1-2121222--1111---3221--22----------------------------2111---- 4353722222222244555-522274545553555546865657444433335574462266536494534-111111111161112133321211222455557544533333333344444311-21111241566331112533332232222222222222522433221322321224434422153555555555455555557556555557744543333335433333333333333334443211-22-21-1222211121111332111111112211111-111111111111111111211111111122121222222222222221111111--42211112111111132324225-2633633333444334344334367665565565-444445444532444343854465454346575555545555555553563443422222222221122222222222222222247E5323233444454533334447333315434454322334232222246432233111232222222222343213141111211111545356634443444141111111111111111111111222333323324433445333444333343333451-1432221122232222232223233322-2222232222232222222233223422222222222222222222222222222222222222222244443333332242322222222222222233333232226255553433344432222222222222-22232222233233443333333322221121233333--------11111111-1-11121111112111---11111111113434 44--445-C44-444233334446556333333333333332333343343354443333343222222222222221222222222225953558445444354715D4BB8888B8955666BA8E8S*72B8G77A787774457678688546556BL47648LA8J46955655*65568E8IE3CEC776655 * c.36.1.11 Branched-chain alpha-keto acid dehydrogenase PP module
[ 334] -----------------------222223222-----------2222222222--------222---- 2222422222222222224-2533252222225545233342224444444444444444444454244444444444222222232244442444422444444444444444444444444422222222222222222223233433333333333333343333343333333333332222222224444444444444444444444444444434444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444424244444444444442444444444222442244222242222222222225444444444444444444444444444444444-44446444444444444444444444444444444444444444444444444442222223222224444444444444222224444444444444444444444444444444464444444444444444444444442242444444444222444224242222222222222222222222244222222222222222222222222222444445444444444444444444444444442-4444422222244444444444444444-44344444444444444444444444444444444444444444444444442444444444444224444444444444444444444444324444444344444444444444444444444444444444444444444444444544444444444444444424444444444444442422224-444444444444444444522222222222444 33112212722111211111111111111111111111113111111111111111111111131111-111111111111-11111111211211111112111111724222334332422322531AM2-4262543242232234231335422414A132D1111444624333O3343353481544583223 * e.11.1.1 Type II DNA topoisomerase
[ 335] 3325329A899A8B9D33223217EBDCBCED131121211124324236438-9BB8AAA845617B -211H--22221--84434-36--6B33333565656HJO25276312-331C99237--AA73B6AFFD63333-11-2112-21-2434314121--2735463628---------------112111112111---211111---1111----------11-1----------------423-----114666667654656577464447566112312211111176-11111111211111--111--111111---1111122-----------1----------------------------------------13238333323333322442222212---2342663333122311-1-113--C887111-142A7B2225447499A99AA8AAF-22722A246M3-GDDEFFWJIJGF83743AAKABAACIN3333333346541579------------------------------1CK64EDDBFRMOORQGDCCBHIHGGGGGAFLMHCCEC-188C79BBC97D6D43374---622222212---435-25333422352222212-321-1--1-3121---------1----------11-2222554261A3A825455434533334444334--1---1------44673344444444434-4444444454444444444657465544345444454354555A44444442-644444444444---3-----222211A3E222242233342222ABA997713122BBBBAG8F6CGB9599A-1111-1112445654554A8C874433433333---------------11-----1-------1--1-2------------------------1-23 --------------------------------------------------------------------------------------------------------------------------------------------------------------1----3------1--1--------------3-----1---- * a.4.5.32 Lrp/AsnC-like transcriptional regulator N-terminal domain
[ 336] --2324111111111241222211111113112113333333312421212334434434411-1-1- 1141722211122322222-2411232222225333658A154754544653456344115443577576311112111111231123222212221--122224221211111111111111311232223222255231111112232211511111111212132322121221121112233311122211111222322222322222322312222222222223122222222222222222221122111222331122111212232221112222222111111111112222222222222122222222221422111111121254222222322112213211211231213323243436322322222233424334336422222222223-33433343232132233452424421233132323222122222222322233321111111111-12111121122222111112111133324333333444443353545533433433323333433244232333332433322321222222443244223323664442121122232334342232332311222222111211122222323355443254245554346433345543332-2333411111166545755555555555-555555555555555555555544453555533533355555545555565324444444444442224111113323342323234342233343352322323333547767786767767656622222222236663555555576543232333332222115111111111-11111212----3-223121122223112221223212222221412 -1119C6-A53436934461332244223142354512211112224344556536625334443654443246244444343356644242424532332227B5-8b6O8549664355447D73F6QhA-C6A3735A97735746655373B966783988A8967968D328A7PEFE5A998F5CBD98BA9F * c.66.1.30 N5-glutamine methyltransferase, HemK
[ 337] 112242111111112111111-17IDFDIE8D144443444436432666BA952223333112---- 1313623111132345533-34--6333333453334377255343343111333442--665332576731111-11-2344415213333-3221--1--64111E---------------22211141124655598555346C99AA85544222233796698942222222222222134411--44445453354555445254334555323252211111113222222122222222222221211111211122221112-11----33311113443333333333311111111111113113331111264--331333313121111111233423331333142446141112133245433323333231131125253344444444425-4445443433612441232333454564455234335431111111122211343111111111111111111111111111112465413544345555524444443433331454224321254263544434231358445615333333324178516A877862883373324325144--3-357733332222223141111111536A833873665659886777766777766866666--27432------55445546666665666-56466666466666666665554443565555565556565567666666632555555555555--24-----311346656544333333334442555454433334555556645544455334334343334666855555898883344444544111122B244333311111111541----1-1111111111111111---33333331331-3- ----2221----112--------------------------------------------------------------------------------------------14235B3F6332-2141CE1F2Wk51C4821218124332121A-2B2B324268A6222J22633112221O111238488-472467768 * c.2.1.9 Potassium channel NAD-binding domain
[ 338] 22-2--6B99A99976-222242F7334113611---------------------------3442-22 3553D2-5--134375544-433348444444553568EE268933352422434546--66A-A6BEFC4-----1111-17---------1-11----343363553------------------------2-22222---422--2-------------------1-------------55433---4233333333443343333533433334554432------64122222222222222311-3--1----1-----11---1-------1112---------------------------------------3-1122111111111211222111-1-316113-761516-25---1--1-7-18773-----559775335555757775575777-33933B37C85-5443446444667B33456F666656C--------6---157311122222-----2---12--2--2----233E3-6FD5DCCACCC88AAADDAAAAAA9BGBL8EAD3399798999AAABD9226----35-------222E983B57-1---------54514-31-55558613---------------------------44-642447544444444444446444446---44--------5444-446445655476-466644474644444644677744544444444444444444492444444--444444444444---4222225555-4734222--------2---99959566648-BBB96A957868A8223222222222-444444444444444444444446------21111111--------1----------------------------------------5 ----116-G86-222243253346956111111111122222221211256556112224441--------------------------12141113222222222-797HA96688556568764576Cf6-7875364655B546543666A5365CAEG3D7468493BG743362Y2223377HB2555583336 * a.100.1.3 HCDH C-domain-like
[ 339] -------------------------------------------------------------------3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------2---------32------------33---11------------------------------------------------------------------------------------------------------------------------------1-2-------------------1------------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --NM--4--------------------------111-------------------------------------------------------------------------4*esjgrlgfddeof**V*d**w3*h*RjbSscjweQpeXTXWR*d*vidPtUiUzYgxSNdMR*N-VR--221I12-7---1-7hiZk- * g.68.1.1 Ovomucoid domain III-like
[ 340] -------------------------------------------------------------------- 146--------------------------------------------------------------------------------417668776-934---4425231244---------------34274425332----------2--------22-1-1--4---543-311553323512-----1-1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------3----------2255335111116213411122---1-221221215-54244243465-83324443342212414242424432655555555232322522234433311111111111111111222212341355536dlpkjhSRPQKihohWWVTDR*Y*IbPX11HGJ9A755OB96985D6675885122222245787656773243--1441-D8B6BBCB2A88B-62132331111112-1-------8514733553A58M5K74HIIFFBIJCGE9NFLL9VN--27B571--111A7446956BBA79A9A7-777A97B98799B97688777733225BB99ABBBBAA9B9AB66638776217556686666761115---------64837232322211111213DCEBD5D223-554643225444643111---------479BE66666DEAEHBBAAAA98884444-13-33-------------------------------------------1-1--1--D14 -1------------------------------------------------------------------------------------------------------------------------------------------------------------3----1---------11-------------C-----5---- * f.4.3.1 Porin
[ 341] -------------------------------------------------------------------- 3D6-------------------------------------4---4---31---4---1----3-----------------2-256843-----1------11---1--1111111111111112------------11--444--O76B5533556---65467765445-4--6-54--5-945C78C*5622222222222222-22221122125452254222222-32111111111111111111211122222221232122111121111-111111111111111111111111111111111511111111155422111111131216663353-2342-43386787123932444631287*2222-----231532---2--2-------------14-21---3--3-----1------3224------------------233-2--3-----------------------------6-333-6511694446CA88857777888868AG5BADH52EFLGBC78D9ACDHA6AD9DDE34FE66DA765FBB4B7B946--55423-B8C9B88J96767A8B6255B8333333-1-------4499744C89CEGA9FC9CHIJJBGMGMKGGHJPGLL--39C8C------5246227555757A867-5556699666586755775555645523232323234232322425412231-634444413644--9B44344888759F7422222222232222297AAA6A7A48AFGGHCACI7867B88CCB875686686ECDDCBBBBDBBECFEBBCBA766GBCB--3-1-3333------------------------------------4914432111-C5- -----------------1--------------------------------------------------------------------------------------------------------------------------------------------3----2------------------------3-----1---- * d.24.1.1 Pilin
[ 342] 22323333333333332333333211111111212--1111112222222232111111112222123 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- GB9FIID8nHHDDHEGGFEEFFGEE7EGGGEEDFGEAGFFEGGEFGEFGGGFBFCEGCGECDEAFGGFABHEAFCFGCDFGFFEADFGGDMFGFGIHGFGDDDHIGDGTGSIIJHIGDGODETIQUBWDz*b-QMuEFGHMFGPHGHGIHICEKEGGJJI7CHKJHCKGJGCIIHHIGI*IHEHGbOQXEUGJGJKHEI * b.38.1.1 Sm motif of small nuclear ribonucleoproteins, SNRNP
[ 343] ------------------------1----1---------------3---------------------- -23131-111111234488-83119388888433332254-4271-12-11-112121--1151222-2-112221111122-111116555-4225--3413332323--------------222254322223222231115-2-82--1-1---------1-12121-------------1-2211122333434444344454422113344422211--------321--------------2--2--1-11211111--1111-11---111111----------------------------------111----11112222222232323332222311-14211111-112212122311225-16442-----798665345633433333333332-55C56B64362-52233364433249431223-1--311--------321--44211-1-11111--12221252212211-13-3143-22212766556556657777676626776999713456763445568334491--283-------21335433321322-12111--1-11212-55658614---11---------------111132176-651436424666656486556445555--13424------21221212444233322-422233223343222222222211211232222222222222222222222--222222222222---2-11-2AAAB166122222221---1---144444431-152454454455444431111--------23449322424453311--------------12995566--------111-------------------------1431111121-1-3 4377D97-C42-5548AE7777799B87777774446B99877555667AA8BI9A5F7978444333344343444345334444444222A383222224255419W8zAEDHDC89675C8CD7IAa*B-GAM5575B8BC859864A73G9C98847CBAC779457EGBE5998SAAA98FJ9kCHC9CBCAA8 * c.19.1.3 Patatin
[ 344] 332-3412111111122-222223111-1--144211-332219D45742AB8135-1445-2-3-16 3--3A122333431BCA66-6E22FJ666669FFGF88BD1D7C31-1-352111321--9A81F5E4AD311111111-463221--AA871944---3523453412---------------65366435334233122235245453331111---1--31326466---1----11-144344445229CCCCCC8D6AACBBA466667BBA212A365677655E85444344544444444445543225424424553345323221668333333325622223212222333333333333322233311122A5CP887879818149652233612442424588234335223222233222744311111667992116344533343333333-43633933345-4667443545437944324523322345455555515543341-------------------------1111-44551255366337537566677B96666276693996133362425475665-6342645524433333--14353E9E65A93A6666335356557832431A6511221112311112222-2222-2132333444423323222234522222255235--121-3------34433434444444444-4554444444444444443444442133323322333333332233434443-211111111111--12--------1536365554452222232246666626335926566555366454534622222222232333333335443333333332221111114222------------2-111111-1-1-1-----111------32122343232353 -1------3233---213143223332111111221-------111222212451-111111----111-21-1-121121---------2-12--11111-1-----511-111211111121111217D1-424-1111111211121111111111----2-111114112--1111----121-31322465343 * d.90.1.1 NADH oxidase/flavin reductase
[ 345] 22232232222222221223333232233323434444444442233344333544432242323-33 2333432322233323333-3333333333333222232234433333333333323222333323333433333343223333322255453523122352555345522222222222222244444444444433442224233325533333343333333233333333333333333333322344655555555355555545666655554444235555555433333333333333333333331244232214433441322323333333333333333333333332222242222212333333333336344444444444433444333443124334344444442443333214433333433333553555535353533333333333-4444442434223333333333345634433333333433333333343334333222222331122222222222222222222333433333333333333333333533333333433333333343333333333333344433233333333333334544443344333243343335444446544323333333222322222224333366665644545756777766577776655755112433322222255555555555555555-55555555555554555555555555555555555555555555555555542555555555555222622222222233334424434244433334333333333352333333333333343335112132214577777777777664444444444444433332233221111111112211111-111111111111111111133333434443322 --11112-31--2222221222222222222222222111111222222223331121222222222212332223323322222222223225232322-33645-4411-----1----1-1----1-2--1-11--------111---1------2----121--11---213445p4543379EC2C54353233 * c.73.1.3 PyrH-like
[ 346] 11--------------11-----1311112221111111111111111-----111111111111-11 331185254443439CA88-8B339B878887CAAA9AGD27553332232433454722669365685642222222122412222233322422---24223622221-------11-112-22222222222222111112121121121111111111121443221111111111113322222212633333333333333324332333324444324444444213333333333333232243322233222323222332323333323334333332333333333333333333343333233222333313345333333333323332222231113334333332323222221332411855711111428563217376422222222222-22322723219132233223333244282243222212444444444422323342222222223---------------22221578943332A555787544336676555565A6579B9215555356655658554441115222222221112446B4522223223323444322423333346112222222222222333443322222123322422142333333224333333423231-2111111-11122322222222222222-222222222222222222234422211222223223322222222222222112222222222221111111113333131222223111121121113342323222334444443333333233311111111112223232222343222222222222222113122222211111-1-1-2----2------------12------22343222221313 1111233-832-3357AA68696B6AA6645455555546555555666665765566455513212212113-2445892222332118F4A5566332324646-2A35DA99GB6866666675K6b*D-DBJ46649556626645673G6635736B42322322423921112X2221232546424456863 * c.1.5.1 Inosine monophosphate dehydrogenase (IMPDH)
[ 347] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----77E----2114--------------------------------------------------------------------------------------------E12d******WecWchh**Y*c***C*x*aefb*ViygVigcW*VQ*c*klkKaoWMMMMlFKeHUOE-2118111114252-24--11111 * b.55.1.5 Third domain of FERM
[ 348] -------------------------11------111111111121----12221-----1----1-1- 139-4-------1-87555-5444495555536464224416272411-3411----3--B41-B2G325---------1-1------111212---------25-31----------------111111111-111111---916-1411111221----12116-121-1------------1-------32222234222333541-3323223---1---------1--------------------1--------1-----------------111-----11------------------------1---------1--44111111----4132------3--3--1-----------------1--2211------121-2-1-----1------------43333336-5--31143544542212-1111-1-11121-------------1-1------------------------------------11--2333352222211--2222-23---111-------1----11----2-1-----------1112-1--1---22131-----1--1-111112146-4---------------------------221--1-1---1211111-111-11111-----1----------112----131-111---1---------11---------21132-11111111111111111--1-------11-11111111-------------113-1--------------------------41111-11-----11-----------------11111111111-22222211-------------------------------------------------------------1-- ----522-2---224348686639B982213111114444444333DA67EDINAAB85667111112-1-111111111111111---5424373344B174C4E--X9*SSuNXCAA4JCDDUQ6VBl*S-SJOAC89U75MA36967H75FCA78C---Hf8OfhPZp**DV243261216DQ***5**11FHDI7 * c.87.1.5 Gtf glycosyltransferase
[ 349] ---111--111111--11------22221342-11211-----12-1--2-211111112-----111 13638-1-222-4132211-14--241111115344434322-222211332535312--54613339B8312223221212512111442514332--4637473214--------------111222322142---11221311131221--------1111--213--2-----2----34------31223233333354333321333254311121111111112312222222222222232222233233233332233221323331-132311112112222222222222222222222212--111---221-6244433452423244222242-22-32--221-2-3143---21-32335221-----124343232222222222222221-33322226132-43243313241172-2-1-122221--11111111111122-2----------111111122121111------22-23221364555632222444733332466442221144233432521271434--1332--------1-132411-2111-231111538232331897855111----------3344444441--2232342322221-24444412454428456255--12111------12221241112111111-111112111111111111244522--33232333232223223411111112-222222222222--1-1112122221123411111111111111132333242432233333743223231454544334334-4332222223434455555555554444---2222222--------111----1---1--------1-------1-111-----21-4 2-11965-F54312655765555555566464555445464445455533646334344556566555477775A665665889774443865869435434447517B2KeZQRRLABD7DKFON9MDf*Q1NHZADCBHCGIG7HBB9FCBRCIHHI67877AA7C6AG6BA55463B21185GACC47832D7993 * a.111.1.1 Type 2 phosphatidic acid phosphatase, PAP2
[ 350] ------------------------11111111111--------2211111111--------111--11 2211211111111111111-111111111111111111421222111111112111211111111122111111111111211111111111111111111111111121111111111111111111111112122222111213333333223322232233314353222222222222111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112122111121121111111111111111131111111112111111111111111111111111211111112111112111111111111111111111111111111111211222222222222221222222222222221111212222222222222222222222222223322222222232222232322222222222223222211122211111111111111111111111133333312111111111111111111111111122222111412222222222222222222222111111221122222222212222222222-22222222222222222222222222222222222222222212222222211222222222222111211111111121111222222222221222222221222221222222222222222221111111111332322222222221111111111111122211111111111111111111111-111111111111111111111111111111111 5555A781NB9466766455666666666655566666665565666666666666677666A78867589B878CD6CC7888888777B869699887776BCG-7GDDINLJNHCABABBASJDUAz*H2LGWB7A8TCEGDBDB9AEAARCDBEG9HW8GDDBR8-C8C995896*576A7QLSX7HC9AFBFB7 * a.8.4.1 Heat shock protein 70kD (HSP70), C-terminal subdomain
[ 351] 11111111111111111111111233334343111111111113333333333111111111111111 2221211111111111112-1211131111112222111121212222222222222222222222122322222222111132122133332333322333334333333333333333333322222222222222222222322222222222111111222222221111111111112222222223333333333333333333333333333333333333333333333332332333333333433333333333333333333323333333333333333333233333333333333333333333333323233333333333332333333333222332233222232222222222223333333333333333333333333333333333-33334333333333333333333333333333333333333333333333333332222222222223333333333333322313333333333333333333333333333333343333322333333343333333332232333333333222333323232222222222222222222333343221111111111111111111111111333333333333333333333333333333332-3333322122233333333333333333-33233333333332333333333333333333333333333333333333331333333333333115333333333333433333333333323333333333333333333333333333333333333333333333333333333333333333333333322323333333333333322311112-222222222222222222222222222222333 44135551C442335344444441434433424442343424444444344443344443443345434354333553555233333333644434334434334335649A7678A56556669H6C1c*7-F8H6664B568656555755D6A76659H297B2334CA4757455e5663595784966765336 * d.14.1.3 DNA gyrase/MutL, second domain
[ 352] 11121122111111121122122143355323121111222222212221222111111111113122 2222332233322222222-24222322222243334333232222222222242232112232323333222222222222222222222212223--222222223222222222222222222222222222233331113224523322222222222232222222222222222225432222223444444444444544434444444433344333333332533333333333333333333323233232224433333323412222222222222222222222222222222222222222222222232233222222222222222222222223232322233222222223212223322222222223223232222222222222222-32233222222233323233332333322222223222222222222322222222222222222222212222222222222322332222222222222222222222222222232222222222232223232323322222222222222222234323322222222232333222343333333233222222222222222222232222322222232232222222333222232332331-2222211----22222222222222222-22222222222222222222222222222222222222322222222222221222222222222222222222222222222222222222222222222222222122222222234222222222222222222232332232244252222222222222211222222212222222221211112-222122-11122211111152133222322222 1221222-94323326574E343647433321321333232354268*3733A6323c4637K2222223235224222224432412277E54AF32342MB14411SI344*5212221232452223M42233132-312F11221-311321I2E432RWGTU321I7B432242F224516K8x4*86BHBm*2 * c.55.3.1 Ribonuclease H
[ 353] 223-2211222222222212222--42--3--------------222121111-23265521232--- 1454312333333277577-77559677777798988EHI46264331444354545411319422A88864333333314431212211332422----2-2251222--------------168777655435222333332-2-1---1-----------2-----1-1-----1----443--222-21-------1-------231112---131-21222222224-22222222222222222222---22-------2222----2-222--------11-------------111----11------------2446A8888898B8D226624456422--9552977682121725611--2113226-----154562227535634343333335-22222234433-42263334544423124423323365666666666233216231111111111--11111111111111111133922233236667755544466655566368763332-233443322634634226222334-------111822-DI4324645777514462545927756351A1--2-22222----------4213222434221413311333323722242233485--23453------32425319AAA9AAAA9-A99AA8AAAAAAA89999755554222545555555564545536446666--233333333333---1111111-1151233---1-2-----1---22222243322166764544155542133---1-1---246693333346444222232222211112262441111--------51---1----------------------345243143121-- 2222333-E52222347554554668534144334334343442324643353344335434233233113122233133322222322356733353334627451775G5464334-5-24444482Gq6-876345315332252-14-34442222474D577H6AD65822284g2114379BC668A525237 * c.4.1.1 N-terminal domain of adrenodoxin reductase-like
[ 354] 222222----------1111111211112111221222222222314411434-222222211114-- 3331433333332333433-3411443333324444433334453223333332333322334343355533333433111233343533332333311333333332322222222222222332232222333656772225522212222222321222222222321211111211114445544344444444444444444445444444475433432222225711111111111111111111222222222222222322212222222222222222122222222222222222222222322222222247676666666656554556555355336336565776875564443334551333533333344343333333323332323333-33333343334323333333333333323333333333333333333333335343323333322332233234222222313313343344434333333333333344333334343333322333333343457333345444333333333554543579565965777775777567678365447663333333333333333333333333344452544444455555545555555555552-3444411111144444444444455445-44444444444444444444444444444444444444353444442334331444444444444114322233333354545444444344434444444343444453555555555556554553222232225555555565555753333333333333311433333443333343433211111-111111111111111111143333444442113 11--221-1---22222222222222222222222222222222222222222212222222222222121122211-1121222211123222241112232436-24142222422121221521223U2-323122122222121112215123123751524121142C222233b3223254762592262331 * d.14.1.10 ATP-dependent protease Lon (La), catalytic domain
[ 355] 33285488888878887345545876774888121121111112212131222-BBBACAC635829C -212H--22231--83334-37--6E34344676767JQV463675231331EAC348--CC93E6GGGF73333-11----1-1111333314111--2735463627---------------111111111112222222222---1----------------1----------------53311---1145555556445454664644474551123122------76-----------------1-1---1--11---1111--1----------------------------------------------------1-137222212222222222222211---222233121111121111---4--C88A1111152B8B33255583ABBAABBABBG-22822B268N2-LEEFIIZLLMIHA47447BHBCAB9KK222222224664128A------------------------------1EM65EDCBDRMOORQGDCCBIIHGGGGGAFLLI9ABA-188D5AB9AA6C6D3333----622222212---141--5-423--14----2-1------1111211--------------------------1155432173A825455434533335455334--1----------34673343333333333-3333333333333333333657464444345444454354555933333332-644444444444---3-----2222-174F222242233342222BCAAA87131327787BG8F6DICA39AA---------2445655554A8C874433333333------------------------------------------------------------1213 -------------------------------------------------------------------------------------------------------------------------------------------------------------------2------1--1-----------1--5-----1---- * d.58.4.2 Lrp/AsnC-like transcriptional regulator C-terminal domain
[ 356] -------------------------------------------------------------------- -----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------4------------------------11--1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2222--N-2----------------------------------------------------------------------------------------------------D*u*ku*iTWUTVcVrkVzT**h4sb*PZZYWPVXRHTSZMYSR*ZkTa*******J5Noa637*G--------------------2--- * d.171.1.1 Fibrinogen C-terminal domain-like
[ 357] -------------------------------------------------------------------- ----G-----------------------------------------------1-------52-----631------------2-----1153--11--------8--------------------------------------3--------------------------------------------------------------2--1--------------------17--------------------1----------------------1---------1--11111111111--------------11---111----2----2--1-1------4411-1--------------------------11----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------1-----------------------------------51-2-------------------------------------1-------------------------------------1------------------------------------------------------1-2----------------------------4-----------------------------------------1111111111----------1122-------------------------------1----------------1- 1---DG1-1----11--1---------------------------------------------------------------------11--1-----------11-1328*iih*nbRMMNNTOslPuM**n4vUrLMONhNPUNIQNPNXLJtPgNQSRNGP*GC9A84L45*4-11----------1-2I--12112 * b.18.1.2 Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)
[ 358] ------------------------------------------------------------------11 --------------------------------------------1--------23-----3--------1------------41------------------------------------------C*W9DA5-1----------*US198j--77J816BL1H-3yl**-7-6-6-S-7------------------------------------------------------------------------------------------------------------------------------------4-------------------------------------------------------------8Q77u-----83S93322-1CKA----------6-VPO*rbl7IA-1366YFSjJDKik5---9QLbT8HMrVr222222224242TTE4----------------------------1--4B-15765-E--161-----11--221-1--1-544-----NC1-5---GG35AC*-9DeF3--8266A1--1-2---L11*74-K124--E----B-K--------133CL---------------8--81--843--11---2122221132111212J146--42------------4----333-24----2---------2-1-----1---238ED----------------3--1------933333333333--P------2223--i23A39----------1---2M--1--Dl1222265W6JF984-8eW---------1222434442E6265--D-------JGDN--F------------------------------------------------------1-- 1-------2-------------------------------------1---------------------------------------------------------------42-5----------------1---------------------------4--1-V------2--9---1---------8----1A----B * b.80.7.1 Serralysin-like metalloprotease, C-terminal domain
[ 359] -----------------------------1---------------1-----11--------------- 115-242433322222233-361144323332323378DC2112144235717652231175913448AB1----111----242622A86747223--4647863653---------------2324254435388877---A4O645674444412333234588868-3-----3----77454223343888798978A9A9976655549874457576211111C53444544255554452-1322211-----21--111--22---12-111-----------------------------------------47521333333333361222454425-1A3274B957555846676532243-977933333336675444555555555455546-645546454562544444544456448676333333445111111111211154622111111----33233333323322122286764666666666666455455686666376664454222233344434334444334456433333333444444354355657466655753535657777A6313335555554547444444454543117746456665468787866867767688661-2445511-11145333434444444544-45444444454444444445553333345444444444444444443444431466646646744223633333555515A4533333333322433355465432225599895755667657555---------3556776676878778999A8988867672256HHEEGG4444445476-----------------1--------2333233333-236 ------------------------------------------------------------------------------------------------------------6-4-----------------------------------------------------11----1-----1121111--6--1--22-1---1 * b.84.3.2 Peptidoglycan hydrolase LytM
[ 360] 11----2-------1---2-3-4-311211322----11----1256731E941-1-1131-311-23 -3G3A123444-1-65622-24--98434445C85865671A3A645311112231-2--98B288EAAG61------2223-1----112---11---221-227542-111111-1-----134155313442444AA23231817544165445263433419A677262222262112125231-111144444432222322251--12334-11231111111146114-2-----221----4-11-1-12-1---21--112-122--21----1----1122221111121111111111111121---212--3-11------1---3-11----5-2--11-23775154-322-----3-324322222222445872217978612222222222-447443463581588335132234553133552421633111111111112363722211111--131111111111111-1---3483-111216445574333333253334318541213121111322443315434472-153-------435663359412321951-1-32315453476573745---2-11112212111--1-12--1355343412332535444224453337233561-34254-1----25443244332423235-34443323443234444423523233422222222223323224333333333222222222222-21322222578972434444-42312213223112212311153686646744433341241--------233352222235543442424422311-1-141333332--------1---------------------------------2---3411 1133357-8432326353373A598A6432746869132343243563658778752976565251321512232212114453222244C55986744214332413X3b8E58953462545B6533CO4-45746355256544224423726557GI34BB87545454A46EA5*9A8DBC7CB9HB677764H * c.66.1.5 Glycine N-methyltransferase
[ 361] 11---111111111111111111-51132121--------------11----1-1111-11---1-11 1591711244511132222-22113A222223544458E92422662112139231131156719276C8211111112-3241111122411411---1611352816--------------1111111111211112211122412122111221111111213321111111111111152211111111333332321423222323351353112311-1111115211111111111111-111115----------------1---1-111---211111111111111111222222222222211111111141222334334342321322111131311111217415--1121111112261153341111111H7A212624333344344444C-544437478D2-D778ABDGDDBE844437A744455775555555535543323-----------------------------134I328IG8ABAAC9C7455577EB666544I6EBHGA1177A3461282F3FB363211266222222212234311126-13123441121111111222125411123112222111111111111111122651312624652333332E333324542471-2211211111134423645554544455-4555654545555555555898232353223232333233332644455543-45554555544411-21111111112135732322122222222244564572742498786CCB4A7955898111111111145582222273A55436555544422221111111111--------1----------1--------2--------111111111-541 ----421-42-24244769D887DEB74444446666656666454566CBIXH897664443453561334343442445333323344B479238BB5133315-3F55133222111111111121121-11211111111111-111111-11133222532334AG13313524F3543133166332584444 * d.79.1.1 YjgF/L-PSP
[ 362] ------11-------------1--411222321--11-1----26-25-29A6-------1111--12 141-7211333132898FE-E655GCEEEEE978B81699-34712-------25--3--464-3485641-1111111111213---1112-------22-2141--11--------------64-4552132323367-111-D55B88867554322313826B89B334322332334213----2--122222413-454335112231313-11-3-2------32111111111111112---1-11312211-11221111111111-11212-----2111111111111-------------1-----------122434323314--222-111121--21---3321---11----2---3113337-----538882235577411121221224-435634543A514664354655344322124132212132222222272233277--------11--112211211-111111174274432213444344835556631776656654222113235237537353345532223443322323213243-254475132433-434613124121112A421222-334351----1-1-12-1112243-332121113222333433334333265---3575------22233111111111111-111111111111111111132343443212222222222222221111111--1111211111211--6-----6544636411--22112222211233223231113255444565344554433212122121223342222233322221111111111113-42882255---------------------------------------1------31-1 55217E6-C322658AADA9886JAHBA99A99BC99CBEDCE66798AELNTaBCDDBBDE2323131342433123342222552136D5A5C63238463667-5R4O563232--122124--53AB3-52611211221-1312211-3--2431122783-1-228792455C*9AA5BDBGU7HGAC9586D * c.66.1.18 Mycolic acid cyclopropane synthase
[ 363] ------2243434522-------493351115-----------------------------------1 --13E414445323QYNHH-HN99OJHGHHHMQTWVJchk2G4E4554422266656822CCH376BAAB71111111--4-3-----1111--------1-1-11112--------------------------555542221--------------------------------------33332---211444443342434333-----134434413--------1--1111-1--1111-1--11-1-----------------1----------111---------------------------------------12-3------------11-----1-2-1-------2-4------1--1-1-1C67A1111164IBC641HCIEB55555554554-56B55E576AG-733343475867AB67474D5555569--------A---1656------------------------------46E522QJCJ5556A73544533B9555524F5MBINJ-25546215478A79C21B--2-32---------14541G22--------------111---665674--2------1-------------------221231514422222233A22222294253----22-------------11---1---11--111---1-1-----1--1111--12-121-11111-1-1--12-------1--11111-11111---2111111111-44-3---------------44454331233188884957464776446----------1111111111111111----------------555566----------1-----------1---------1---11111-1------1 ----443-421-53787E7H77AEFG9AAAAAA8A89A9A79AA9A6877A8BE8B77788855555535556555523555555533389777A755545A8C98-59283333261222232242426T2-22722223125-22221222225224342333323335-243-431-321133299A352465671 * d.38.1.4 MaoC-like
[ 364] -------------------------------------------------------------------- ----------------------------------------13---------2241-----H7--------------------------------------21---B---------------------------2-72223----------------------------------------------1------111111---1--1---------11-------------41------------------------------------------------------------------------------------------6--1------1-----4------1-11-----2-32--1-------4---3----------------------------------------2----------------------------------------------------------------------------------------------------------------1---------------1--1--2-1------------------1AA-------------5-1--35--2-127C--------------1-------------------1----1--------1111----1------5---------------------------------------------------2-------------------------------------------1-1-21131--1-------------------------1--2-----------------111111111-----------------------------------1111-----------------------------------------------4-- ADA8PU9-Q9A-678456344445444444444535333333343466464447557566665342432443455121214545442437E7577477555556781A**rSXTVUPNMQHNNRufIbK**Y8eM*PONNZGPYMLONPNULLhMUOMOJREENODEJGMdACWN4JLK*DCBGDQNSY4QPBPNaLQS * b.69.5.1 Regulator of chromosome condensation RCC1
[ 365] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 454566L-SDB566747556666666666676666566564666666666666666676666655555-5555555536555456587746575664444675A9C2IZAojidifoWTVaVRQpeUlV**ZGkU*XSUWaQWZSTURWYaaWqSdVRPKaiHXOPFPGFV9AVJ4DDA*86588C7DH58999YaVUK * d.148.1.1 Hect, E3 ligase catalytic domain
[ 366] ------------------------11131111111-------12211211212--------111--11 2221211111111111111-11111111111111112142143611111111211121111111114212111111111121111111221111111111111111112111111111111111111111111212222211121333333322332223223331545322222222222211111111111222221221211111211111122111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221311111111211118822221111112211112213111121111141131113111111111211111111111111111111111122111111211111211111111111111111111111111111111121122222222222222122222222222222112121222222222222222222322222222342222222233232243232222322222222322221112231211111111111111111112119989C512111111111111111111111111122232111312222222222222222222223111112222222224222213333323232-33443223223233333332222322232323233333232222332223311222222222222111211111111121212222222222222222222321322222222233432222223331111111111332322222222222111111111111122211111112222222221111111-111111111111111111111111111111111 3333B661JA934485633455655555545455555555545555655655575857655598888868AB87DFD7CD8888888675A6675C7665554ABG37EOAFKHCEC898B697JF7N9o*D1FDN7896J8AC99A779A56O8A8AC7DJ7EB98P5-759685797*66687OORX5KB69CDFF6 * b.130.1.1 Heat shock protein 70kD (HSP70), peptide-binding domain
[ 367] ------2355555542--11-1-23111-124-----------2112211111-1111111111---- 12-1A213113424CGA44-4D11BB444448DGKGGGGI2G9F-1141111333354--64715475454---------453111223333-4221--1332222231--------------11212311111112211111511---------------------1--------------64634--1623222223223222222232222222455322233333352333333333333333333321-1----1-----111111-1122122221111211222222222221111111111111111222111111112----------32112-----11-4--2133424522433231---312C79G-------HBC2-1C7FEA33333333332-22522A2512I-111111511123342E56785365568--------311--44------------------------------1C774-3985A755566666655575777747848BBC92244443478B5B876234----63-------11-22A395533221312231435443245433487231111-11111111111111112215--5543A1436435788769576687667687---142-------44441425444544455-4565444545444445345555435334444444444444444444444441-333333333333---6111111111-8821111112111111111998794633121EEFF7A87A77778433222222222-433444444455445434343333-------2555555-----------------------------------------------2-2 --11682-213-232BC968878A6A888677666626664668875856635656735555533222232233322222233333233344C9781323214786-5I452222212213333333335B4-3343331423522342242322113122-1111221--23312432D23242388B96233----1 * d.38.1.5 PaaI/YdiI-like
[ 368] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21--234----5-------1---1--------------------------1--------------------------------------------------------221***tk*qWDAGUyN**Fza***3pm*9KDI*Za*O6ZHBB*C7*M*s*****AfA8rCbWFj*74----2-----1----1-------1 * g.22.1.1 ATI-like
[ 369] --141-3323333333-43333332--21232444444444444454465775333212122-13-23 2353423322213164444-441157444445655577CG35481221322243222211547244736521111111-23254434344463411-11-313322333---------------444575555555558644445234233233222111112223645311111111111123245331433333333433433333333343343334441122222274133333323333333222222---22-----11--22111111121---2-1112211-1111----2222222222122111111111166265222222232354661---414-13346566656531564447112-432222----1355442225444544344444345-11511312332-6335334334444523345565554441111111132211647-----------------------------21551248865766877712224478444434B697AC71256484465778475335232322111111111147917733554354555-6565544466656364652222222231-2-------2322333334343325433333333433333243335-1-2232-11--111313212221211122-22-2212222212222222664322314143434444433334311111121-11111111111111-3111113333345462222221111-12223322312222A344444444553767344112--11-1222242333334243222222222211112252443444---------1--------------------------11411323333431 ----115---11344674465556566445444444544444444444456766556544444554543564545766665455553334D574444444454666-3534343434353423263363FP6-7582334443433343243233323435726233A32B32723343R2323355664765554337 * c.1.10.5 HMGL-like
[ 370] -------------------------------------------------------------------- E6I-------------------------------------------11-1--111-11--11--1----11------------554799A86-C23---274BBE8GD6--------------252354644376111111--2-5425324--22212424243D2673-------1-----2111--11312222222222222221111212212112123------A211111111111111111111-----------------------------------------------------------------------8115-------1-1-1222--------1-13133622312-1-----12F1FF77C1111178HFPG8GFDFEB34243443223-KPDCKGKH565-B66B989877458I6BDB55545543544444444968433A3---1-11111--1-22132111331----1439923332589989754443669666665955EABCK-3FGD79779NG97848GD9B7A57-------9696BH55C1487836E331-6A477C855AC8ACA-641---1111113233333335324868545GDCIABB6CFGFDFIIJEEFJDHQLMF---B86B------34453543334333533-344333433434333333357645232222222222222222253213233--433333332333---7121123667G8A54111--31----1---44454391116768786A9B779879679---------B5779444449ADBBDC76765366323233E9DD57FE11111111-----------------------------------11-6C21 -1-----------1------------------------------------------------------------------------------------------------------------------------------------------------7----C-1-------3-----------1--A-----8---- * d.225.1.1 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
[ 371] 341--11432112111229A64588389499521233143333473GC4DHFG-6467643231--43 5554K41A898233E4299-9J1-7A989994HDIGCCBJ-85B698C5431D6H32511A951A6EAOH41---1211141712132-11---------911664543---------------231325312136554422295A53634211221-1-112325675-11111-11-1--58312331355DFDFFCHH5EFGDGI766628DAF5737533522322F6324343222233222446662252472321289215513221222211121--111----------11111111111111522---2221349233334344344414412237-22234351GB6372445542162126146443----144C88735859844444444444A-7D47C7728F4-A889A96BA9AB3834976756335462222222284423435-------------------------1-1--2233-4664565566654453BB9555551696959951464225377835342766535343221-121351238-1613394253233-355334655435347442-211-2-111-1-------2112456453213322332333334353374447754----452-------1224312221211132-2223411334213222223663533-2211111123212111133221223--411111111111---2-----1111336324221----------14334422333724425546446446334542323422233545333339544486--2----122221172441122--------1-2----------------1-1--1---33233-21131611 ------------------------------------------------------11------------------------------------------------------------------------------------------------------2----3----------1-----------1-2---------- * a.4.5.5 ArsR-like transcriptional regulators
[ 372] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122CB6-F67-124212322332232333333443151425523131223222-3332132233332233532345444233333-1-1111122--1-111B57-4H*******eaYXXZlZ**Oyh***5zy*WbRQpYhtgGkcRKnYO*hqeimDGGYUYDAPDBWV**8-232----11A428263-813335 * d.42.1.2 Tetramerization domain of potassium channels
[ 373] -------------------------------------------------------------------- ------------------------------------1------1----1--------1--2-----13----------1---------3373-1------72224K1-3333333344433335-----------------------3233-----------232----2-------------------4--------1---1---1------11-----31--------4--------------------------------11----1----1---111111111111111111111111111111111111111111112---32222222-2--3-------1-------------2-------1-k9----------------1-----------------------------1----------------1--4454444454---------------------------------------------1-----3------------------2-----2----22------------2--2-1-1----1-2222221-------1--3-----1-------------11113122-----2------7-----------3------21-4---5HHIE--2HIIGCK4-G-9---3--------------1----------------------------------2----2-2-2-22222-2--2----333----33333333333---1----------32-1-------------------------1344443363453333222----------111--------1------------------1-AA5599---------------------1--------------------------1- NFB997M-*lhQAAA1-11113111131111111111111111111---2---------------------------------------------1-----------7*WQOOWYQRLJEDGUHaUAYL**X7eQl8JEERGMYG6KCCASAAcNRILRCCFZGJ6BE47U12gP-JKK*9B89HHLNZ1SLGNGdUTr * b.76.2.1 Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
[ 374] ------------------11111-22222232-----------1121211331--------111--23 2232332333332342244-43223444444232223555333333323333555433222343465444311111112222342222324322221--242634333411111111111111133233433333433223332233333333333333333333333323324343333433333322233322222323223222333333322234323222222224322222222222222122223221222221212222222222222222222222222222222222222222222222222232222222222222222223322222222232323222222222222422222222222223433422222225552343345344444444443-54544546332366654584458753343326333323333333333333326332232222222111111111111111222223343234733766667666666667677766676456545446644334444434473222642222222322335452224242544432434542333333346233333335454724222222243346235437357243543333333333334233532-2342311111133444444444444454-444444444444444444444444684434444444444444344444444334344444444441142222222332133451113331333333333333334333336667476865544356633333333343334333333333333333333333333222233223311111111211----1-111-111---11111111121223222222422 11--232-311-2233433333353522212222223222212222333353333434333322222222222222212222222222223242224444124222-231B454536445444443384GV4-56B5343544533443343374944532635323433532542443F2233364563534342225 * c.65.1.1 Formyltransferase
[ 375] 11112122112111221211111222223133-----------43-13--222111111114431--- 244-B11111222165411-14--37111111767623941B264132123-41312311214252648B2----111212131-11111----11---22-1-2121---------------11111111111122222---52-11211-23-----1--1---43311111111111112211111-2-6A9B9BC98489BAB9213336A881114443222221461333333333333333111221213311111222222512-125752223111323222222222221111111121111222111---1-1445333222222212331111111121-211113-11-311111-1--21422211111173F9B11321-4-22222222216-988965982B3-B8867788A9ABA33212451111315222222221342-325-------------------------------29-39CA56ABBCCB433337788554527B5A99FB-1445356338444I7-42-3438311111111-2142-34-113--22221-66313551323226B5421111111111-1--------1--23254-111322222222221133212312113---2323------66632635556566654-5565756555565665664888533335555555555555556B53444451-511111111111-----111122221-635---------------87778152256-DCDE99A87A8B94987144435434---1323223531348613133---1111--1411-----111--1--1-----1---1-2------21--1---211222222226-1 11--792-B5212267AB78BABAD876755456666555555455997C569857645322112111111132111111111111111A64A6523441321915-2b2B11122-2111122222234B2-2231222512221212121114212333345442323524322643g34292432BB5466A4666 * c.33.1.3 Isochorismatase-like hydrolases
[ 376] 11-1---1-------1-111111------1-----11111111-----------11-111-111--11 4373833433332344444-44335743444544446599344844644443A6733333567375689633333333522112222233332222--1222423231422222222222222334133324324222221131246564464433222232244556543232232222223333333222233333233233333342332233222221114444442321111111111111111111-12112121125611111312332113431122111322223323231111111111111111111222332258222222242523222222222113342222222232222222233233333422222537773354454533333333335-67967A57443142214546545728333443545623344444444666233541111111111---------------11114223235333366645465555448755553533945753433365365576484344453333332232244533523232322224222245534453344642222322322222322222222222222255339342334334544444544444444444312543432233344544544445455544-4444455444454444444676443335444444444444444433344443333333333333333342222222225334433333333333333444444333327244444547433544544333333333244444444444544443333333333333342222232--------221----1-221222111111311111123222242123221 22--211-411112233335463555722222222222222222224344456544323332113111111223222-221111112223423342767421222211522453321212123233253AZ3-43423123225-2223231141112211-11212411611423222b2122385993444351112 * c.36.1.6 TK-like Pyr module
[ 377] --------4444445414-----------4--------------1----1333--221--2312---- A9I1I--1---11113333-331144333331333353422225796212--59A112--5412A33BB25-1111-1----5--1--MJhQ-R44---8L-46U2F-P--------------1221222222-257787---3123374421133111222112477A2-1-----1----1211153-21-------11-12---21311-111--12--123333331N--------------------522-11-1111771122-1132-323---11111--33322223333--------------11---111-41-211111111111A2111232E141--24-2--1-2-7-123366---1-44332111111211242--111211111111111-44342323121-411355277533111-111111-1---22222222122-2----------------------------------3-1------5786633444233455455-4635211-----1--21--11-2111111-1---311111122--1-1----1------1--11---2-12222-8-1---------------------------1111-44-7--7---1-12--2-3-23-21---3-11------2311-424444444444-3444433444343444442343----12322222222212122211244331-111111111111----11-1111-12-----------------------------151111-2-1----11---1-2--1----1335111116343366ABBBA7762222----11----11111111114--------1-11----2---11---1331-111121I42 ----55C-522-233MFMGQIK9TNPJ5566765455444433666MGIKFHLPLLIBCBAA556555156565455255454556222BPCF8F7667447765617A7E445744542254478364Ee4185H343635344145344313422536BJ5C757C6GEACF43332811132OCNQJIE35DA77A * a.102.1.4 Glycosyltransferase family 36 C-terminal domain
[ 378] 33124322222222222323322433335454223332333335453435554645545253232211 3551422222222233344-4322444444425333334423443232222122522411443134244431111111212341133233332333---232356233333333333333333321-12111122677334446544433342222212322343244652222222222234422211-34465656466565656554444476544453446444446744444433343544433434744344333435544444452225555554555455333333333335555555555555433444333555458555555575534555353553232336365353544322345-22725433411111125472123332311111111111-43333732144122232233222312223222111112222222222211115521111111111111111111111111----132421-222-2112121212222112222121212245-134325143-3442-112454311-------222314287934432664321666666784534577572111111111111111111112115111-1361137121-1111221111112-22----1323------21331212222222222-2212222222222222221333111-22322222222222222221222221-222222222222---323223333312512--------------1111111--1111333321123434423231121-11-13222111111-11111121211222------535555552222222222211111-111111111111111111112111121212322 4423A97-D543336232233333333443343223444423444412322343212333332323333233333233323333335655B43676534446444424G36334321131333273354Ed3-3343322333531333272373223432-156234223255249A7X55756973A2AC6877576 * d.157.1.7 RNase Z-like
[ 379] -------------------------------------------------------------------- 126-611111212123422-26--2222222243348579253841-23113132-1422445-667A8832111221----4335333332-312---2111313222---------------1111111112111111---311111112111111122211111111-2-----2-------11---411121233221422251414443214---2111111222424323432133333231112-3------2--132221--1121-3233222222222111222122122222222223222222222312214135333334334315222111-111141112332321-22322313-123-44443332368CCB889989889A899AA8879-DCBBECECC871999888888989663234657777566555555555446465511--------112222221222222----2444645655C55575565555558855555577976773487A868977668757585665644444444574998B54264352735863444444444576564442222222222123222222223225549A54466565467666667666655755561-44664-1-11155477555555555575-5555556575555555556677864776655445555776856C5557665318777777778771125554546666857534444434322243346678775557658999767677576789722212122258A9744354D86557786868555222222742222221111111122--------------------------2--232222211-- ---------------11---21-----11-----------------1-3---1-------------------------------------2111111111-11------------------------------------------------------------1------2------11------322A-26--5---- * d.2.1.6 Bacterial muramidase, catalytic domain
[ 380] -------------------------------------------------------------------- 3-1-H3222235-1LDB44-44--NE4444467434EJdc-B79---1-3--132113--HB12U7HKAY4-----------------------------9---M---2-------------------2--------------b-6A8-DEB--------------IAY1-------2--------------E112126163142671--3388119---62--------M1-11111111111111-22--------------3------------------2--63--------------------------------------3----5-----J-77----2-12------223--1-----------1-1---------253-O---17---------------221221223---255B12-1-1B-16-2---2-----21---------2---1-1----------------------------------------57868BLAEE94465SSSRAN6456-5-----7--7--9---52-------9----------5--1-------121------------------Y8-----------------------------23---2----------9--------------------------E1F3213222C2CC522-2242225255255222222114F7ek3111111111111111132222222--365666333363-----1-11111125K-E---------------44464-3---96FHEEYMMM58AB81LCq-------------7-11113--1-1141111----------------------------------------------------------------9-- ------1-----329EGODVNbTjihY669BBBRWQEBAA9AB566JAh*WOPMLBUPF666------------------1-----223844G141222-125111-17-2---11--------2-------------1-------------1-----21131522112136411--11911-212113V112135225 * a.28.1.2 Peptidyl carrier domain
[ 381] 22213111111111111211111143342344223222222222323212332222233331111-22 3343344444444342444-64334444444444444444365543534444445443334444333555322222223222321122222222221--222222222232222222222222222222422244333332224144443442244333333444344443332333332332323333423222222222222222322222222234312223333334222222222222222222222222222222222222222222211113333333222222222222223333333333333233222333233134333333333344444222334223223422455332233343222332233322222234332223333444444443443-333333432422333333433333222223334333322333333332442232311----------111111111111111-122432223332222222222222222222222234223222222322222323322232343222222222233223233233333333332546444564333344333222222222222222222222234333254343232354544343354333333331-23223-1-11133332423444334333-433434344343444344424333222434444444444444433323323323444444444342222222222222333223332232232123323333333233242222333324334333333333333343444555555454533333333333333223222222211111111113----1-1-11111---1111--11133333232222212 2223323-83123323333344443433333333323333333322122222221222222233233333443334424433332344434233232222233334134378676655264553883838b5-7484654755654544555483755637G35333323843434323P3323363663643433333 * d.129.2.1 Phosphoglucomutase, C-terminal domain
[ 382] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111--------------------------------------------------------------------------------------------------------------------------------------------------- ----TUF-----E9F444455665676656454655555545544455444544444454446555565666565656675655552227BA4C663233346JLX1V1SMokZiegZWX*Xid**S*b**e7*d*TSSnlTVYYNXZRTftQtYSPWR7FKHEFBBSACQ8GLC------------1-4----4444- * a.117.1.1 Ras GEF
[ 383] -------------------------------------------------------------------- -------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ --11HKD-842-99DABA9BBBBACB9BA7BACACBBBABBBBAABA9A9AA9AAAAABBBB6688673855777564558689B86894A6B7766555457JHF1K36RytcsnUQOLIRXQ*rTwO**kAzY*HPNTgKPkOFTRNOeJF*SZUUXDOXLEDB7HCCQ9MHF4244B65442EBFG9D9227A891 * a.238.1.1 BAR domain
[ 384] -------------------------------------------------------------------- --------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-----------------------------------------1-----------------1---------------------------------------------------------1--------------11111----1111-------------------------------------------1-----------------------------------------------------------------------------------------------------------1---------------------------------------12--3---------------------------------------------------1---------------------------1-----1--1--111------------------------------------------------------------------------------------------------------ 32--88J-C54-54B9C987898A7A88878787668ABAC987778788A9AB789798A9765545243256534344466655576B96CA6F6776797898-D*7WSSTUUWNQOJNTQucLoR**aCpP*JRMPbLOPTJMMNJSLKqNOOOKRQjLJHcDGCFKAHNF4EGL*IHDIFFGGP8LFBEB9AAZ * b.82.2.6 Hypoxia-inducible factor HIF ihhibitor (FIH1)
[ 385] 111-1111222222211422222-11121111-----------1------1----1-----111--11 2361632111111178644-49114D4444439CAD46C9363B3342143277A43511323132A667221112111-1-4221--1111-1------1--121312111111111111111111111111-143333---2443213331122333233321232421222111212212321211-4233343444434544454244354443333433222222422111111111221111111131314412111331144323333323-------1--11111111111-------------121---1111-2-12-------2-1-1---11--1---111--331---11-1332----3133223-----52AB93344744322342444335-33A34C3C57218776767A898978222445323365722222222A2233111-----------------------------32243-3A63A8AAA988333188CE777737C7I9A86-4553343335388882332312342222222232223-22--331121--2-2-2132212222232-11-------------111-11-----22212331323443333334333333333333111211311111133221225445565655-4555555535454455552555442215355545555545455243233442-122222222222111-1111-11112336422241311212222233333241123167674654454453434-111--1-11422322222444332243333333------2---111111111111112--------1---------3--------1--11111431- 11--222-7331333C8A98878BB686655556665444544454563349EC45555666222111-211212222321222221114738342666532344513D566546453343333474738P3-34833333244323322324524426334643544DD422429573Y34334C9FJ9D75586559 * a.100.1.1 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
[ 386] -------111121111-1--1--------111-----------1------1----1-11--------- 55S-B233444634B7788-8B118B88888578576AHA1448825-13312235-5--225-834247111114451-24-------133-6-----35257D2F-4-------111-----31-11-1112244345---5-11-233-22-----2--11-1313-1-1---------33411---21344434223233442331335333312253222222225813333333333333333335325-111411-433323--13212-12221222322222222112112222222222222321---2222--122----------4-11-11-514-1113--11------------1-57-F7222------2636---11121----------3-66655857266-9322543656325444524531351312222222241122-33---------------------------12-2352-14342789AA8545555555666646E494552-234512312723362123-1-11-111-1-1----213312---1--------2------22222BA11113--1-----------------------11362231-5154263344414344244-------------53351313226366632-234323442326233333334544112442444443444444492233332--1111-11211-----2-----1311-431-111211-----211-5556523-22214443624433326-3211111111111---111111113113546465---2111---1111111--------111-------------------------122221-113-D15 -----54-2-2-236DHJBGBBCNFKL8545457535776576465NCAMNVdXHHGG979733--1111115-111111111361153AQBHAD5D8C854F846-3i993433314112133311217I3-3321-342-132-2132111-2---211222471411-343213568123623RYLH783798BFB * c.69.1.2 Carboxylesterase
[ 387] -------------------------------------------------------------------- 85E---------------------------------------------------------------------------------11--FEHE-A332--CI676AA9991-------1-----475744813527-----------211--------1221--1-1135--11---23--1-112----7---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------2A1155543845736UJOACDHBEFCAA9BABB9BBA-DCEDECDI6B427874555655559D36547733233123333333333331171FFXQOHHH222444443444444445346-255433221289999747777666677776667A6555345532551239332-34-3422434D22662112221C6-2111-251--11998657B565685D3513431122221216-1111111112A118915ABB57527AACA75G89A9DABH8FF---44651-111165457764HG7475854-K5487967C9J8655555687766566A889BAAACAA9D99A566365664-6AAAA9AAAAAA--23BBBAAC8BC27834444535534212444667664545838333334434333342222123132112BEED77777HFCCB33665674432222---322-------------1------------------------------------8738 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-------13-------------1-----3---- * f.4.1.1 Outer membrane protein
[ 388] 11111111111111111122111132233433---1-------1-1--1111111111211---3-11 243-722222211221122-221122222221222223442222111112224342211122133224443-222111--1111-111334313222--34444743341------111----11111111112122222111316342221111111111121-233311111-11111-11111111-1111111111111111112222221112221212111111-1111111111111111111111111231111111111511111121111111-111111111111111111111111111111111111111-111-1-11112121-1121113141-222-1111111131-111-1--317111111111112131111111111111111111-11111111222-122223333223122213322333322--------------11--------------------------------111----------111111111-1111-1-1-1213--22322---1---1----11-------------12-13441-222121222-3231332335444552211111111111-------------1--222344224333434322233333323323--12111------11111111112122221-1212122211121221222111113321111111111111111122111121-111111111111---3-----111123411---111-1111-11133333332331311111111211111222----------2223222222222244555555553333----554455--------11------------------1-------22122222223613 CB45A8C1L452A9B68A846675654655656777465565576567767767567566666583443643548343444665766765C888786677446CB719HDFHHFFHFBD89DDCIFBMDf*G-IDL9D98DCDIF6EDCBEC7IDEECD9C9CAC98E89C67B78IHBz8A7CGNJMP9RFGC6779F * f.51.1.1 Rhomboid-like
[ 389] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------i**o***heljnkf**k*f**w-*p*eehe*hpuoTmbhb*fR*mWNoqKaOFC9H6KAFS6665------------------------ * b.1.15.1 Integrin domains
[ 390] 222222222222222221222222--------222-------------22122222222222222122 3333333333333333333-33333333333333333333333333332333333333333333333333323333333223233333222222222222222222222222222222222222222222222223333333323333322233333333323232333323222223222233322332233333333333333333333333333333333333333333222222222222222222223----------------1-----22222222222222222222222-2222222222222222222222239322222222232333332333223223223333333333333333233333333322222333333333333333333333333-33333333333333333333333333333333333333333333333333333332222222222333333333333332222223333333333333333333333333333333333333323333333332233323333333333333333333333322232222222222333333333333333322222222222222222222222122333333333333333333333333333333332-3333322222233333333333233333-3323333333333333333333333333333113111333333333333333233333333333322333333333333333333333333333333333333333333333333333333333333333333333233333333333333333333333333332232222222222222222222222---------------------22222222222332 3313646-721-446221221111111------1------------11111111-11221-121122211212122222221112211133323344332122363-534D7977467554663794C4Fj91ACA353693466355459348356663446A553956795B54568w88866677G2D87686752 * d.101.1.1 Ribonuclease PH domain 2-like
[ 391] ------4222222222-46542234--24646-112211----34132144342------------42 3341532333332346644-4511744444435555448544442221411134533311446143455441111111111133151311113111----3-224441311111111111111123222223212-22--111416555557557755555555557575353533353533443331113454444444444454444455454444545211-111--5521111111111111133332----------------------------------------------------------------------2324A333333373715444675332111221466954113382213113135444411111576774445224455555555555266666666453-6554556555566744346533335445555555533335633---------1-------------------13544333336856888699996687999987888466414446544445444544446464331353333222344-23353443344441535155562335324234111111111111111111153155336254444143433333443333333443443--26321--33355441544444444444-442544444444434444457557334555555555555555554444444314444444144442313---------45466333313111111111444443434444888867866686656561111111111544533333455551-2333322233334421443333--------11------------1------1------1111111111453- 11----2-1-----333333333333322222222222222122223333333323333333223212222-22222222222222222343332322223-3522--B-------------------------------------------------1----1---------115655x55555F6ED3656623336 * d.134.1.1 Nitrite and sulphite reductase 4Fe-4S domain-like
[ 392] 21-111------------11---211121-2-------------1--222211-2122221--11-H1 7Js1C------2--2------3--12-----13222-43433--332--221612115--252-92554331111111----4-----898A-J66---4D699PEADB-------------12---------2-799A9---D45533445-22231433153272232-1-----1--1-3--11-1-2-122222222-2223221-11112221111-12------83------------------------11---------11-----------------------------------------------------1-111111111111--1331111-111-5-11452113-11-12232-1-J1A5679-----1111-2-------------------11-11-11-2---111----1--1--329--1---------------1111--61------------111111111-11-----26254211111------2----112----------1-11-----212--3-------3---12--------211---4127-231-42111-1111--3--5666E7-1---------------------------1--6-3C96C-99888CCBAA97ABEE7EM---3-11-------112131---1----1---------------------1112343111-------11-1--1111----1--111111111111---9-----1111--1-1---1-1--------------------11111112--1111-11------------1-1-----311-179AACA9AA92212---2221111--------1---------------------------13111-2----C15 4211755-D724656A67AB9768D99BA7789564869657767665888AHC88998557334654334354675-663444726555E7659E4336654598-7A6EHMBCEE8799C7ALC6K7j*F3QBN8C97D69B758755C78C789BABIH6A778H99XALAH3387h6634AHDFE9A85586576 * b.70.3.1 DPP6 N-terminal domain-like
[ 393] ---------9C5--V---------6QO25-5------------1---I3-8H6----------2---- --B--41A--1----------3---6------5-----B4-1HP----------------25--1-4E11------------3-------71--A-3-------9--1---------------3----55--4---22A5---N-*591J4w----------6I2E73Wc------------5SI6----B71-2125-6G4182144-4----2-2eD2-----------------------------------1--9--3-----22--------1-1--425---B--551-1E15--------------33---223-1P--1------1-----22------1--H1-T3VNUXD2----135G-----L-----------6-47-2-----------------122--1H1-5-----13-A-54-918-----1-A----5JIHIHHHH425-11---------------1-----1-----4-2---3--------2-------------6-1----151-132----E---1--O41-A--J----------------G-1-R8------3-------75A5K2A--416E-5-------------------------11-1-2---5B---923963-92-K-K--1------312--------1C2--4116444313--45-7T--FA1136B5664---112I--3-2----17-3---7-PNFcLPb2-E---1----1----4------79A1--1--2--------------7--1O*---2ED--1-1----6--------11111111-B--*-----*1-8A--9B-55***------R---LL11----------1---------1-1-288-d---2----21----------- ----------2------------------------------------------------------------------------------------------------------------------1-1----------------1----------2---------2--------------------211---------- * c.55.3.4 Transposase inhibitor (Tn5 transposase)
[ 394] 11-1-13555555553-212111231122153-1111111111-----111111111-1112211-11 5353541222221286433-3311473333326585A8KO2319272212229A8343--549134749411111111----6-11--11111111---1333441423---------------11-11111-115454411136-211221----------11111111-------1----3332411-51122222242442322243221124215714111111115421111111111111122221-------2---222211---11------------------------------------------------12--1-----------211---------2---1331-1-1-3212111--2-2C554-1--146IEF2148577555555554554-33C33C47D66-B66977A87A55A98445993233388--------442-3522-----------------------------31CY4-EC959FGIFEA68884DDJDA99929KEX9OFD25BB8BB974CAG4JD442----211111111---389221--1-1-21111111111111-222236-11--1111111--1---------11111111311214312333333233332321324---121-------32221212331211135-3515212522315552555556225516463656666656536743144451-144466646666---3-----11111124A--------------34444422123937777664B267772344111111111-111222222223252244444333-------1----11--------------------------------------1--------212 ----333-421-3226664C775GCE93333333335444444333545AACKJ7785444421311111111131111112222211132263223222214322-2D36463232321133234242BN5-435342143442122-13-13333265532756443452253222371111244664332344335 * d.177.1.1 FAH
[ 395] 5511-21-2222121121422423211221-3734233232121222216332221434322221-35 333231121111-231234-45223344444463334232445452434221122111227541243656511111113567332532658A1B22---34242438432222222222222245334324345433321111143316442113356632214143253231144454253233221122131111142221213441111431111412-2133333343122222222222222111-11---1--1---22-1-----------222----1--22222222222-------------111---111-22325444334383713444444234323864432232343342222352242A66A22222217444443423422332333333-43533334344133362373443432656435555534444444444355459A31111111111--11111211111111111243665322237555576444455876667366565455327643334232453654232444422323326664473943355A77697A3534554465352316333334256448654333332333423227423344552444454946544664646471-245431--11123333323334355533-3433434344355533555333542325353555555455534533433332245555554555512422222222223464433434345556555443433434446233233652342443233333332333445463333334333334444433344443246567777--------431----------31------11-----12122221223731 22----2-21----2-----1----112111---1-1--------1--1112121---------------------1-22----------1----------------3F-A2543542323233231246B2-22423223224233222242422232222121111113--222112L431324223-222222235 * c.68.1.13 Cytidylytransferase
[ 396] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 657A99C-WD5-79A556698879799555545776555555545545567666675655559755454575655664665555465668G7596745555A9GEH-G*DQbeWbXRIHFIKMIwgGaH**X5bUrHFLGYKLXMGNIDCPEDYIQKKKGDKCTCslnuxcFNGK3JF7pCBBBCTUZm6fHQKCAB9I * c.13.1.1 CRAL/TRIO domain
[ 397] ---1111-111121214-111--32--221--236-1-111111-122125533333-312---3--- 24315---------52255-5533535555544555-43325363441-4414441-3--321121122212111322--15121111AB53-422---12122A36-5---------------11111-1111122234---21325733623332111-1343322221--1111--1-1414--22-3-1333333332333333121111333111511211111119--------------------1---11---------11------1--2122112--------------1111111111111122---122-21144232456535245227111864-1134--211--1-22-2232---12C711------56966--267786----------2-55455459-61-43366547752367422632444421-11111111-44-4324-----------1------------------2353--1-115455554444455844444-46582533-4223683213B9465129-21733-------11145614551-2--51----38355361556453A23511-------------------1-1661122581-2214322212122211222143--1-2-3--------1----------------------------------11122-1-----------------2---------1--------------2111-12112137-3111111-1111---111121-311-3766661654623221445213244141----2-----1--2244333332231222--2-44------------4--------2-5-1------2-------1211-111111311 21--891-4124333554344445444555445555454555555555445445555555553232331333333231333333334431215121322211-332-287ZACFCILGFFFGFFLMEMDc*G-RGWGAEGICDHDDFFDDDB8JEGHKP599ACHB6887A2293245162223242224274344423 * d.3.1.4 Transglutaminase core
[ 398] 11111111111111111111111131121111111111111111111121111112111221111-11 33--9323445111-------3---5------322212341--3822-13336461-4--223675A667322222222---2-----1111-1-----13--16-71B111111111111111-----------33322----111111111111111111111111211111111111114321122-41444444445254444485443445511125437777776B2333333333333335433454127C22433771199262332454445544455555555555555555555555555564533244465118A443444463513--24423213-2121----1--1--42226222--1311111111212241112422255554555557-222223332C11D776677CB9773111143363565432222222253331--4-------------------------------1-1-22222466764544445589444424647334411232212223124361111322522222222111121-12---12-111-11-------11----12------------------------1--1164A3122223442222222333222222221-111111111119799875CBBFCEFECC-BDCCBCDCCDBFCBCCDC7GEG67554FBFFEDFDDCEEEFFEBBA9DDCA518888887788781111111111111112475558583343369961111111111524434364533333356611111111114448555556457A3322222111111111-4------1111111111-----1---2-1-----121-------41--13111-11- 11--111-1---13111111111111111111111-1121111111111111111111111111111111111211111111111111113111111111111321111-212112211131111111-121-11111-111111-111111111111211112111111811111211B11221534914212211-2 * c.124.1.4 D-ribose-5-phosphate isomerase (RpiA), catalytic domain
[ 399] 323233433444444221433321733637B6111332333331223127767112122322211215 5451222111211122322-23--44222224433322221323231112111121-1--2211212342111111111111321211445424112--3839765365--------------163123434157111--111319KF6A95222224256368356756141111141111112111132132222222212222222211332221112111111111121111111111111113222111111111111111111111--11111111111111111111111111111111111111111111111112111111111121212112333131111111111112131111111111217222512222322211111222222-2222--13-22222222343-6553665897884154565233339473333333334442112--------11111122111111111----152323344357887875433366974444447597879-145423555532342246341254222222211263246645233266111112242537412124813322322222223233333335453522661C5A85DB7766665A866658488567--1631511111165344656666666666-66766666666665666667774422687778788888787786655656521544444444444112523223222227556333212111112111333333335633888898A87AAA77889634324413379845555586676654444444322221--111222211111111211-------------------------11111111111221 1122112-311-112422222222222222222222222212222222232222213222221-----------------------22232323331111123444616----------------------------------------------------------------112756M33287F57G1C96333232 * b.38.1.3 Mechanosensitive channel protein MscS (YggB), middle domain
[ 400] 22313343444444443422222-21121212222111111111111121111222222113222-33 4532622222212132222-22222722222224442322323243131113314113114444355576211112222111233222112211112--22222223222222222222332222222332223312222222223113111112222212211111112121111121111543335521131121223321322233333432123242325688775511111111111111112112195215611424751168225234769111222222222222223222222222222222222211122222214C222222232215112222112314111211211231122122342222444222222113232222222233333333334-3343333246224335446666B9223322345535534222222222222222211----------1111111111111111122431222222756768344447774666655764325522334222222222232222222323333333111222222222221123222222332232222232222222222222222222222222222225353333252255444433555434334331-2222211-111A5336638779898877-7878978777787988998A7A334479D96999BB697B779874566663268878888888811223332322222234233423333332434422222222223333433454243443322333333333247654444434455453333333333332223222222---------11-----------------11-1----16322464442412 1111121-311-22221222222223122222212121212222222222121212222222222222-2112222213222222211112111112111212232122112222212221222432333B2-3251122222222223323332321525A22111811723422111H1112242243221541122 * c.80.1.1 double-SIS domain
[ 401] 22122232222222223233333265556554112111111111126232587111111113333123 21312---------25422-22113322222242331143344221---11212411---113111331-2----1111111522222112311--1---2-1121433--------------15413342334355544111355536444333311111123225475------------3224422-135334333443445434124435443333-1--------1-11111111111111-1--12-11122111113311221-1-11------------------------------------------1----1--1222222211211-441----12--514-6223-31213211111--122422C1222243C577963323322222221227-4C5487943821244255A465352211132633332223333333334432322------------1111116131111--11131281111-174434583555754655554423D443---6412422213233131333-11--------11341149541458143556-525546334234234661---1---------------21113332211231122321111111111121111211--41121--11122332212222222222-222222222222222222244422--13332333333333323222222222-222222222222112211111224351231---------------------1---5311111111151212111-11111111122121111111111--1111111111111132222222---1-1111-1111----------------------111111111113-1 43--NJ3-611-55924335442444422222211123222222222236334H133233233216212213--122122611121372AC749BA111--427-3-1ABE8CAAD365355C7EA398Ja9-C7B2774B76B82865293386DA7B112DUA9HECPKHNJ-2876965546Uam*2ik86-121- * b.15.1.1 HSP20
[ 402] ----------------1------253466644-----11111-32--1----------------1--- 12213-15334-1-B7756-5A--9E555557ABBBE8UP13181-23----635321--536-254233-----------1311---1111-111---422331142311111111--111123323332334422211---21A7667755633466766875344843232332232341-1--11----1111111111111111-----111-1-1---------22------------------------------------------------------------------------------------------13--111111111111111------1-22-1-14521111-121111---1133221-----57ABI2145235222222221224-44634937145-443343B6558A68211356423447C222222225111421111111111111111111111111111111136D325B876A78C9BA5556AAAF666637JCMBIDE23756DA353A9A6DE28634233232433332114F832331111112111--1-------112132-3---------------------1---33454353625567333333655537454377--1-21311111143463426554644466-566654465654555655699955343545545545545555445545555--4777777777771--2-----122255458333533233332222565663534371888A79579AB895555---------2465655555665661133433111----222-22--11------------------------------------1----------1-3 22-1111-H631111312--1111221111111111-21112111111225323112122121111111111-11111111111111111311113222211111111N3823213322-2221322213C2-223-21-21231-2-112-141423331125221223211223B97*75354CCLH2CA7742227 * d.15.4.1 2Fe-2S ferredoxin-related
[ 403] 33223232333333332233323123411222222121111112211214112111113111222211 1121211111111111111-11111111111111111222121222322222222223--2211221222111111111112211212111111111--111111112111111111111111122222222222111111131112211111111111111111122111111111111112111111112111111321111111111111111311111121111211111122211222211212122211111112111111121211111111211121111111111111111122321112222111111111112111111221211131221111113121213122222111112111-11221111111111111111111111111111111111-111121111213111111111111211112111111111111111111111131111111111111111111111111111111111111111112222222111122221211-122222221111111111221122111111111111111111111111211111121111111122222111113411111111111111111111111111111222312212222222222222222222222--11111--1---22222222221222222-2212222322222222222222221122222222221222222222122221-2222222222231141111111111112121111111111111111111111111122222222223222223211111111112222222222222211111111115645111122111111111111111----1---1--------1-------1111111111-111 6523876-N995EFB55655555555555555555655557555556656555555555555565545-65355555-665555555555855655555557565735G6I68B8937797779BG9C8My7-C8H69AA98794778A8AB7C9775AAIS6e*BA646GACF966A7p666D7D64A586357K6A7 * e.8.1.1 DNA polymerase I
[ 404] -----------------------12--4--1----------------1--41-1----------1--- 4QW-6--------------------------------121-1-1-3--1-1-E42-----552-41-LF81----------1--------13-1-11--25-69A6e25-----------------D12----6-34466---E-941-554114431--1--C-t21HQ-------1---------------11111--1-------1222-3------1---------35------------------------------------------------------------------------------------------11-411111111-1-3122----122--1------421--------------M1---------1--2----------------------2--4---1-----2--1---12-2-1131-----222--------------3---------------1-------------------1------------1111--11372131--11-1-----------1----1---2--------------1---8D3I111211-111112114141-2-23Ab39--------------------------------81-7----1214-1--321-11237---C-----------------22--------------------1-----2-----25--1-----------------2-------22222222222--11---------2-5--------------------1-------6-1-11-1-------1-1------------1-222222--1-1---------------A-22--88--------2----------------------------1-111---1-f-- 1111B7*-422-222--2-722-5-11-------2------------1CB7CB676-2---1-----11--------------------211-3221111111332-AM4kVNSZUbPOPMJLPmaObMw*P-gNnJNQORQOSMEMOQIaOHkMHDNPHVMGGCA6C69M33C51465B238212112-11-8-111* * b.69.8.1 Integrin alpha N-terminal domain
[ 405] 11-2--2222222222-2222222211222222222222222222222323332221-1--3112-22 4443211111111222222-211123222221133333642111321-2222121112--221-24511122222222-231422121222212---11-211133231--------------111111111121333332225322322232222222222122322322222222222223333322142322222222322222243333322232433112222223212222222222222222222-------2------------12-221-------222-1112111111-------------222222222-23-22111111121232221---2-21-422223322222-222222--3322222212112328552243333222222222222-3453354433314333236635332222232363563113333333364423322111111111111111111111111111112242224543445554433333554533331333745532222553444444774333222212111111122223322322222222222-111111132222234231111111111-1111111111211122332221312312222222222222222222-1-2532-11--132332223334343233-3323322333323333333344222323222222222222223333322231-233333333333111111111222224232111113-111-2112333331212111222233232232323431-1--1---111121111111111222222222222222211223333-------------------------------------22--2-222212- 12--445-522-44589788AB8ABA877766677766665666566578889A7776555555666646757666756666666635559995568675537879-635A8H668655564A5765A5S*8-B6B4745C5689357845838A445758746559K79G66954442G3233498DD7D52243332 * c.77.1.1 Dimeric isocitrate & isopropylmalate dehydrogenases
[ 406] -----131222222222211111--------1-------------11--2121-13-111-222--11 3631532222221131111-12112211111222223233-22211142221343233113352333C7611111111-------1--11-1-1--1--2C77893A57------------------1-1---5122222---2-232122211222221122224232212-1111211-1-11--11-------------------------------1---------41---------------------211111112111111111111111111111111111111111111111111111111111--111---1-11-2111111111--111--1-1-------1------1---1111-1--5-166621111111-----------11111111111-11111111111-111111111111114331111111211--------13321-3-------------1-11-11-----------12312222223333333333333323333333322222223332222222223222412112222222222213212-1-1----1-----222-1211-5525B5-2--------------------1----22111412455515878855466664656746--13121------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--151111122221211111111111111111133333322221111111111111111111111111-112-1111111111111227555534411111-2-333322-------------------------------------21----------5 2111673-844-664544344444444444444333244444454444464564444544445655544655657552555444443335B3436333335335664756TIGEKKLECGEEBEFEEIFf*I1LFSBDBEEDDIDBFDEDIDBLBEDDCCOdNRCSNdNZiGKIP3555Q53264658945D348BA93 * d.92.1.13 Leukotriene A4 hydrolase catalytic domain
[ 407] 22----1132223343-------12--1-231-1---111111---1-12343---------1----- 533-212555412248655-58227544444386764335141221211432412422--3271533254-11111111-1121-111212--11--11212412-132-111111111111-22324312231221111---514554342132222222222-464C3322333323313522-1111--111111--1------1----11--2---1-1-1111113121111111111111116513141-11-13-3132222-442213443334121-32-----------2222222223222-221112221-131-3334334333-2---1224---1-1-1-1-----2211-----11113545321111119662236566622222232223-22222112365122211131323213222---1111---444444441--12121---222221111111111111111121221355311----1334312222233332222122351213--113-2---1-1-321212--12-121111111--3112--211--1211--112-22111322316-1211-----1-2-2-----------1121114222312-11111112211111211221---12211111111111122222222222-23221222122221111112331212131232323322333321111111211111211122112112-111112221--222111112111111---22222231121122334232345342544111111111122222222222222311-1---------111-775544-----------1-1-----11--11111-1111-------1-----4-12 7623656-E442334564686457876334525535554555544456678A9E339447673333444343243333435434343333646444444444676626F9HBHDCDE679668CFE7G7W*A-F9E9868A89E7558B6954HDB8BD8DF98593343849876778*B9878GEEL4E7CC88559 * c.3.1.3 GDI-like N domain
[ 408] ------------------------211-2---------------12-1618C2----1---------- ----3---321---11111-11--121111112111-652251D251111--2311----754-414422--111-----2---11-1111--1------41---2411--------------567469745A25222-----3-*ihgddLHJAA655666OKKVelse474444574444--1-------222423433-43353321--12333---312211122159----------------1111111--------11----1-1---111---------------------------------------------22593333333733131--22111--------113----1---------3-2ABB8-----144-2---2122-------------23326223213-2221111212112-129421----1--------------14E1333444344477663366666366433331121---42-C1111--48CCC--1-CCCC-8-11------1---1---15--H--111----------------11251-3----16----1-2-52A1222-15q41------1-----1-----------1--23--131-1182111113511112143232---4-2----------12-13CB-5---42-B25581-673B2B221532-----7--2312333333223223521243323--44444424654--22333332222--2-4---11---------2-------21143322213132111-1211----------1212-----1222211--------------N-111122--------11-------1-2--------1--1-----------------1 B6--777-923-11-D1--1111-1------11---12-1111-1----------------1-------1---------------1----211-----------11-2*Me4395421222322874C6LgD35741432333333342334243622P444BGf822122--*-446L*57543B567-75431-1-2 * b.80.8.1 Pentapeptide repeats
[ 409] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------11--------------------------------------------------------------11------------111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1----------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1----2------1----1----------------------------------------------------------------------------------------------------1-------------1---------------------------------------------------------------------------------------------------------------------------------------------- CC55685-9---**9IPNDA899GEE96655559996666676544NFIOLOMOJHNLIJKIdI875458D4F89K83EAAFFDMF542t*QPFSR9899DGAQYZ-4E4E8F796GA8BIO87FD8LAd*G1J7K59CENB8*H79CC8I95XAC9AI54422532D114UL5C3442I54348a***G*i69CBFD7 * b.50.1.2 Pepsin-like
[ 410] 11121-11111111111222222122222222111111111111222211222111111111111111 2221222222222223333-32223333333323333232222222222222222222222222222222222222222222222222221221222-12222222222222222222222222222122222222222222222246222222222222222222442222222222222211111222222222222222222242222222222222422222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222233222222244242223332223232222222222232222222221-1212222222222222222222222222222222222-22222222222-2222222222222222222222222222222222222222222222222221122222222222222322222122222222222222222222222222222222222222222222222222222222222222222222222222222332211222222232323223222222222----1---------------1--1-223332222222222222222222222222223-2322233233332333333333333333-3343333333333333333333333333233333333333333333333333333333333333333322222222222222233333333333333322222222222222222222222222222333333333233333333333333222222222222222221------2222222221222222-22122222222-1212112-11--212221112 4445555-D553555455556555555555555555455545555534555555455555555555555555555454555555545555A5555565555455755565A685555644455466484HS9-7594554745743554365374775557546566654A44745555w55535889H5B65566554 * a.80.1.1 DNA polymerase III clamp loader subunits, C-terminal domain
[ 411] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-----------------------------------------------------1----1-1111-------------------------------1------1-----------------------------------------------------------------------------------------------1-------111112--1------3----------------1--------1111---------------1-2-----------------------------------28-----------------------1-----------------------------------------------------------------------------------------------------------4-------------------------------------------------------1--------------2233332333------------------------------------------------------1--------- 432268A-61-1AA9A8899BB7B89C999989AAA9A9AAAA99A88998898689989668888997885798B9489888877BBB8E589995555255OON-CY7ZZZWbdQIIGKJOHrhFfJ**a3mS*DIHHOHQSFGKFBFWBAjHSLLPFKPHHJ79LABWBHFF26FReA8A75FB8S9D4786C78L * a.39.1.6 Eps15 homology domain (EH domain)
[ 412] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1-----------------------------------------------------------------------3--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2----2*-----------------------------------1----------------------------------------------------------------B51***uo*yWZMMXwV**R*i***-*q*KaQVsXh*sDidKDvID*Q*iWv8378Xa31-----3TB-2--1-213------2---12346 * g.24.1.1 TNF receptor-like
[ 413] -------------------------------------------11-8--1313--------------- 1-2-1--1---------22-23--1122222-3333-111----11------121-------1-1---24--------------------6---------1-3721478--------------1----------------111--22432214422------22146652------------333-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-1-111-----12322---11111----------1-11-11-1--21-111121111111---4142-111132-111111111111----------------------------------42-2-1-------------------------1---2----11--1111111----1-------------------------------------1---121---------------------------------------2-4---1-------------------------------------------------------------------------------------------------------1----------------------------1----------------------222---------1----------------------2-----1-1--1111111111--------11---------------------------------------------------1-3 1-----S-1---4577BC73443373355554555553232333335576DDCDFG696664533464324223224331322122444DC8BI9A989E78BPFW-AB-xUUPYYnLIE8MLJdUMhLh*M7hMoHLLBYIMMKEMKEGRHIeMPUMG3-B37T*5*CGG55I-1VPC99A7VBHWu*7YHC5----3 * b.118.1.1 FAS1 domain
[ 414] -----------------1-------------1---1112222111-24-11-1-2321111-----11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 4254CC218225CBFCBCADFEEFDEBCCACABADDADBCACCDCDBCDDEDDFACECDDDDBCCBBA5CCBBEDCCADCBBCDDDBBAAFBBDHICCBB8CBEFE6DMAQJMNSKLFIGFDIIhSIREp*v-SLZKIHFWCHPLGJHEFIFCTEgMHIDC8LEPHAMGKJ7CKDBBCBwAAA98PRNhDYH78DBAB6 * a.22.1.3 TBP-associated factors, TAFs
[ 415] 111--111222222111-11111-4--221122111111112223-22223131-------------- 4411C43555522311111-14111611111143332334311384312434866216--334696B7794222223321113--111---1-------131-14-61B1111111111111111121111121144433111311111111111111111111121121-1-----1----3211144143955555556485556597776968634345668898889B4444334344444435443563127A11423661199352211453446444465555655565655555555555555574443344486338B6656676867372246643324133432223322424766593431123111-1111212231112422255555555556-222224432A1-D667656B996531-1143342344422222222263341114------------------------------1211122223477874533335577333323545334311232212223125371121111421121111111121--2--1341311111111111122111112-112111221212111111111-111-115492-1111332111112122211121121---1112------9787564ABADACCEBB-BCABBCABCCBD99AABA8FEF46434GAEEGEFEEDEEEFEEBA87ABA95-655555445555---1---------11126444737223225775----------3133232534222222465---------13339444445437933222221111111--23221111----------111112-11412111112331111111421123222-11- -------------2-----------------------------111--------------------------------------------------111--------------1--------------------------------------------2----1------1---1------------------------ * a.4.5.51 Heat-inducible transcription repressor HrcA, N-terminal domain
[ 416] 22-1122144344342123332212111-111111---21112-----122-1-33232342331-11 2252611111121143333-321155323332445446C745472343211165733511676274C66431111111323261113233331211212455656563633333333333333222122222252455221112533332242222222222222422433222332322223323322143444444444344444446555444446633433444335322222222222222223332221-22-3--2222221121111332111111112211111-111111111111111111211111111152324333333343444332222212--4243222424313335344534431633422222448554335545655554454455-44544744562164424486546548323656556655644444444466236441111111111--11111111111111111236H4333223966578544456649555538547575311333221112145531132111221111111111254135342212241121778467745334333251112111111111111111112322332222224322334222333222232222341--32211--11121222221111111111-1111111111111111113344212313222222222222222111111111122122222222211133332222221131211122111111111144444121115144442333343432332111111111-11121111122122443333333311111132333344--------11111111-1-11111111111111---11122141213324 33--222-722-22222223222222322222222222221222222223223222222222211111111111111-1111111111133323333342221222127242433232344242552428P4-6443333222322244323242332435523433521E22324443m3334498FB2983552224 * c.48.1.2 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
[ 417] 33--1121-------1--1211--21131-2-------------1--2------212222121-1--- 8BL2522122221151222-23--2422222144443A44412246621342434224-143--955434422221221---2-----4479-955---49477H-587--------------111-11111-2123333---2222222212211112121111B222311111112111131311---2-121212112-212311113311221211-2--------5----------------11111--11111--------111----1-----------11111---11----------------------------1-------------2---------115-----------1--221--1-K-6A88C1111123221111-11-111111111112-2222222313--2221223131--1156B--1-----1-111111112335--8-----------112233234212332-----756642111121111142333111-333322211---1-----211--111-1--------5-11-------1---3-1------11-------1--1--333397-------1-1--2----------------23-6-2997D-F9AAA69BBBA9ACDE9DF--1111-------111-111111-111111-11111111111111111111111211211111111111111113--121111-111111111111---9111111111---1--------------------------3322222221122222222-----------232111115422289BBBBCCBB4434---1--------------3---------------------------13111-1----7-A 1-11667-7352999579775759787645566555553433355545669AA544973423124222252232322-222A9A45333795757A5342544766-6IAEHNDDF99797978HC7I8U*D1LDJ7987B69B669B67867B8999BBFJ6755CF89R8AA82784Q11168HAFD6894874448 * c.69.1.24 DPP6 catalytic domain-like
[ 418] 11121222222222222222222222222323111111111111112122222111121112222-22 3222622333322224455-5311825555543555422223322332333332243222332253866921111111111132222222222222111222222222211111111111111222222222222333331114242332222222222222222222232222222222222222211134322222222222222322333322222342223333332322222222222222222222312133132-23323331212233332222111111111111111111111111111111133111222211112-11111111121111111112112113376343422242121-21223322222222233432223333322222222222-33333233232222223332222223222332333332222222222222222332222222222111111111111111222222222222223222222222222222233312222222222222222222332222222222522222222222222322222222222222222222222222233222222222222222222222222222222222222222222222222222222222221-232321--11123222222222222222-222222222222222222222222232222222222222222222222222222222222222221222222222222222222222222222222222222222222422222222222222322222222222222222222223222222222222222222222122222211111111111-------------------------11111212222322 2222564-8321344453787B7CED6443333363554545533344335332339443333333332333333333333333344444845478434335354512C375854545344444574F5Kb61777554544353456644326434543444548A467p22444444*444448AGN5IC5533337 * a.128.1.1 Isoprenyl diphosphate synthases
[ 419] 11-2111---------121111-1-1111111----111-1-1-1-1-21111---1--111--2--- 4341634524223244455-552238455432455564454655525122223344221145657346654222222212212122433323-222---1---1-2121----------------1121123221111--111-11111112221111211212121111-2-1---2-11-2112211-2232222213212221123333232213221111111111221111111111111112331421111112111--11111111212221111111122222222222221111111111111111222111113111111111111111111111111111111422111111-2-111-111143556-----223332333334322222222222-3222222232214553235222553333232233332222222222223322645-----------------------------14353344454444444544444455444444455556514455545554474555577423435555555--353424223433133334-44445446444442636122--222223---------1112133563646646638766678A7777889B7A9--14656------43445665554545555-5555555555555555555555445455555555555555555555553554-442444444444--1411111222255555444223-222-3222233233423296777798999A9999999---------24558666665555566666666664444224-433343---------------1---1--------1-----------1-----25-- --------------11111111-1111-------------------1111------11-111------------------------------1---------1-----B-------------------------------------------------2-----------1----7CBC*8A6ADups*1*V3321114 * d.58.18.5 Glycine cleavage system transcriptional repressor
[ 420] ---1--------------------123-114------------------------------------- 297-422233311122222-22112222222211111112153521223---111121--5351A2132211111122233181241244431333----6342623-2----------------1--1---12-766541-15-D88855655552354226849A8C634332225232246444111-32333335433435553-13311455-352-258GGECA832111111112111121211-424211232-13322223242212343333233111-----------2222222232232122111222314438999B99A786354327754531411333IN451131312331-2-12-733F-----19LFMA74FDFED66665666649-IPJKFQEM775-7667DA7BK7AB451329368B78938111111115221-G67-----------------------------13393-34413CAA7A94757688848888497ACAEE8229A4B5689CCDCF4426212542111111123777B5431232454755414233222332212253222221111112-3-------43322442423534131235785433322748246341-13624------33224223334443433-3333333323344223325343343322523242224232332223322332-344444444444--14---------134322223222323332242222213---4345463446342444434---------13222333334422233223223211111--32332233--------322-------------------------1222212122-2-4 -----------------1---------------------1----------------------------------------------------------------------------------------------------------------------1----2-1----2--1-1------------2-----1---- * a.4.5.4 CAP C-terminal domain-like
[ 421] 2211-11112222222-------2222222222222222222222222222223-1---11-113-23 2442222222222222222-2222222222222222222222322224222222222222322222222422222222222222222266664622-323515554445-1----11--1111-444444444442224422222444-4444444444444444444444444444444442222222-4564444444444444444666664446444422666666644444444444444444444424-2442222-442244-22222222222222222222222222222-------------222222222246244666666646444444222444-242242444442424422242-4424222422222222222222222222222222222-222222222222222222222222222442222222232222222223222222222-22222--21111111111111112112222422222222222222222222222222222222222222222222222222222222222222222222222223432222222222222242222233336522222222222222222222222222222675443424646555544455554544544-22422222222255554555555555555-555555555555555555555555554555555555555555555555555415555555555552224222222222222234-4424233312224222222222222222222222222242225--2-421-336657777777644444444444444442222222222----------2-------------------------42222444442221 ------4-----222222-222242422222-22222222222122222224442222222222222222222222222222222222224224242122-22467-671----------------------------------------------------------------24444i444248AGA2C44475554 * d.58.18.10 Aspartokinase allosteric domain-like
[ 422] 44-4114333333334-34444443444334333344333333334433343544411411333--22 3333354444422222222-23222322222233332433232222223222333222--224232223222222212----333333333333---33-3333344331222212-33-----33333333333443443333454644445444333334444457743333333333333333333-33333333333-333333333333333444333333333333-33333333333333333331---33-----33--331---3-333-------43333333333333-------------3--333----33-33-------1-35133----3-3--33333337333--3333331-43334333-----445333333333333333333333-33333333343-5444333443433433334343443333333333333333344-----------------------------33333333333333433333333333333313333333333334433334333343333333333333333333333-4343444333444333333333333333563333333333314444444443333333333333333333333333333333333333--1333333-33333333334331433333-3343333333344445443444333334344444444444444333333333-33333333333333-333213333333434333333-33333-333433333333333333333333333333433333333333333333333333333333333333333333-333333-------------------------------------13--313333343 11----3-1---3333333234458553333333333533333323333333333333343333333323333334333333333333336335553333243334-5812111111--------------------------------------1-111-2-311-113111515443Q3334448A63A76653333 * c.1.2.4 Tryptophan biosynthesis enzymes
[ 423] ------------------------111---1----------------2-------------------- ------------------------------------------------------------------2------------------------1-1-----------1-------------------1--1--11------1---1--1--11-----------1--1----------------1------1-11-----------------1111-------1--------1-----------------------------------------------------------------------------------------------2-------1--------------------------------------------------11----1-----------------1-----1111---11-------11---------1-1----------------------------------------------------------12--1-2--------1-------2--1---------------------------------------------------------------------------------------------------------1----------------------1----1---------------------------------------------111----------------------------------------------------1111--------------------------------11-1111-121112211-------------1----------------------------111133-------------------------------------------------- --1---------1-533121111---1--1111111--1--11222-1--1111-22111111--11-11----------1111--1--113331121232-2A24-6--Xnnn**xOQTSQgT**N*T***8*m*QbSTcKYigJbUJLhON*TwccWBLMHPLOHePWxDIG8-12-------1---1--------- * d.110.3.8 PAS domain of steroid receptor coactivator 1A, NCo-A1
[ 424] 11111111111111111------25236657423444433333244543378622223222-----11 6495A22222212133333-33113333333333334455366356443323574332115563325674322223223143544343436517323---42434363411111111111111232333233334555993336722222222233222222222422212222222222225443367234533333443244345457554644556655334333335B444444444444444533331211331222244223322333-211122111122222221121122111111111111121-222111177579898888898A58448BA9C3834654766678579B89B997424644433411111224222111211122122221213-22222222213-344322322224233222121122222111111112421131111111111111111111111111111111121111333235475443333355324444344533333225433456334445343342232222222122245332B764775675545486655485467867A44222221111111211111122223465334333345334333324333344334433211343111111133343323333333333-333334333333333333334333244332333333333333333333333213333333333331122222222222723322221222221222222222222222223433333333333333311111111123444343443433322243443331111123322113311111111312111---11-11211111---2111144444444438431 ----232----21111111122121211111112111121-11111111111111111-111211111-11111111-1111111111112111121111111222-1--------------------------------------------------1----1---------11----------1112111--1111- * c.6.3.1 PHP domain
[ 425] -----------------------23333-322---2--222234C-5I-2424-2-2122-------- 2523------------------------------------6---7---3-------------3-3---------------1---3333-------------------2-------------------------4-36666---33DAD9FF24455------677-66E7--------------1-----243--2-22222222222343343222433433322222232------------------------------------------------------------------------------------------C546B444444444463554---43C--44383445327526233883--85-B779-----229BE3339D33F------------66966A6C23--5339776777663-5-3-2-888825---------2552-79A------------------------------2333352222555555C666655666668385639999--555D5555725B55AB85569A9-------7432AA7B66638A7PHAAB5KINEEFIACKJKKNB524333-3333335555555556839---B9-B8B4444-8999986688878966799--23768------33332332222222222-2212222222222222223---3322233333333333333332-2-22221-322222222222---3---------33I28---------------222221222229CCCBCCCHBCCCC8HHH---------76667EEEEE776AA98ABBBB9AB3333--G57744545555555533--------------------------3-33333333-5-- --------------------------------------------------------------------------------------------------------------------------------------------------------------4--------------1--------------4-----1---- * b.40.7.1 CheW-like
[ 426] 11-2--2222322322-2222222321222432222222222222222333332231-1--3112-33 2322322222222223322-22222522222222222255222222311222212222--222323422222222222-221422222222212---111314332332--------------122233322223333432224222222222222222222222222322222222222223333322122222222222222222222222222222222112222222312222222222222222222-------1------------111212-------222------------------------223222122-24-22111111121232221---2-21-2322222222221222222--2122322211111423334222222222222222222-22422522222123332232223232642434222223322222222222223221111111111-211111111111111111222622797464445445333344663333-354776882266523344634355333222254243333322243222322222222222-434344333333324233222222223-1211111112222222222543435443333334333333333333-1-4422-11--143433344444444444-4434443444444334436343333434343434443434334332244442-333333333333111411111111124333111213-1111222244454444445255554455444544444212122121222223333333333444444444433442221332222-------------------------------------12--2-2222221 11--223-311-2246644755588754444444444444444454444655865456444444444434454455415544444444446464485554444656-53455833353654344457468e3-4393554354323353334667633525C23226623A25322223k22222534A5442253332 * c.83.1.1 Aconitase iron-sulfur domain
[ 427] --1----232523322-11422-51--12-32-----------------------------1-2---- --2361-2---2-18eP55-5I--GW55555AHGMH6JWo-Z4e2--3----552225--12B145F7635-111----1617-----------------2------12--------------------------66686---32-------------------------------------1-122---11----------------1--------22323--------1----------------------2------2-1--21--------------------------------------------------------12--2222222-2--3-------1---1----87-1----1--------2--733A-----2-MBD1-7C5BC633442443442-34B33E3A856-411112321432A6472859222427922222222511--823------------------------------67F9-7vaIgGEEGJH66888AAHG998959X8VTgne36896748A8P8JAQT456----31-------2-2922-121-----2-----12--3----111111-6---------------------------1---1-4-3--1------1----1-11-1--------------1-2-3--3443333333-2333333333233223221------111211111111111111222333321-----------------111111111-2313---------------44324242222155554767342455223------------------------------------------111111-------------------------------------------------- ----111-----11386B79777FFGA3323222226888699433446DAGLH88D446454-2---------2------222-2---57565473111214533-2B45352232422322325252AX3-6332232532432223233372632A23212222233E1222-11-----111--86---111112 * c.123.1.1 CoA-transferase family III (CaiB/BaiF)
[ 428] ------------------------B1152-64------------------------------------ --41D21467A21197633-39--4M333333BAABJJqi242C59512112MJO534--44B2BEUDIE21111344----72-322-----1--------------1--------------------------22221----4-------------------------------------6732411-41122222233232222254442223114563--------72--------------------1-1-11----------1-----------------------------------------------------14--22112222-2--2112--------1----12-12113251212------622------32H99--9775628888888677A-126--914H72-AAAC668988CAF941-57H3344586222222225441-113-------------------------------8C--7ibLPKMMQMJBDCC8NNTSEEGE5EVGdTihT11DE8D8B87O9G7RO232111111----------556-11--111-1-----353264634----12-----1-11--1---------------21--2-124-4----------1---------1----3-1------44542438556866656-56757575655767767779A9341227376757777757566943444433-212232222323----------------681112-2--1-11111778573846491BA8A3B8B369A73555111111111----41111112123--33333222------------------------------------------------------112111---- --------------------------------------------------------------------------------------------------------------------------------------------------------------4----1---------------------1--2---------- * d.110.2.2 IclR ligand-binding domain-like
[ 429] 11------1111112---111---2111--111-----------------111-------1111---- 1223522222223262344-422243434443444435764545344433335564452244434374644-----------3---1-3332-2--2223434333333333333333333332---1----12-45533---421111111111111111112121131111111111111334331--324555554553545554575564555455444422222252233333333333333344432-2-22-1---2211111111111111111111122111311221111111111111111211111211112-2244333432411111-----1---3----21----1---11311-13-2422222222225334233333344444433443-225225233422233232643354223233342222232222222222222222222222222223222222222222222222235832232233443443333322243333253333333233332222222444222221112322222222233322-1-3----1111--323143421333353-22---------------------112223323323344434333343333333333441-2432222222232322322222233322-2222333222233222223444223532222232222232223222222222222222222222222233333344442232322222222222222243334232223244543333333332222222222222122232222233233333333344422221111222221----------111111-1-11111111211111-------------2243 33--545-833-3343332354344433333333333423333333333444443353344332222222222222222222222222226333333333433546-3559466656455364446584Bo4-84F5454554744444444675P53449F47445434C54555644w444458AFD3B555A6684 * c.43.1.1 CAT-like
[ 430] 443233355555554533242221321--2---21--2--------1-1--1--222222222222-- -----------213-11-------------------1122----1--211111111------13-2------3332222--2-232122122-222----1--121---1-------1-----2---------1-22222-------1-11-----212-11--1--1-11111-2-1121----2222-533222233223232332212213223333-12311111151333333333333333434332---11-2-1---221----32-2222222-22-22-----------22222222222221--------2-12-3-------1-1--22-32-112212----22----3-2-212-234--12222-------------------------------1--1-------2-----------121--211-1--1-1---------222---2-----111--11-------1----------53-2------22222242---22422222-2222111-22222322322231222221222-------------223-21-234-23321----1-1--222-2-2-4--1------------------------2322223-2213222223243333322323-12---1------3112-3-3333333333-335433332333333333332334-123323113111343333-2333333--1--------------2-----1----2--2------------11-44444242222222222223222224223-----------111-----2232222222222222222--1122--------------2--------------------1----3223522222--1- B7AB47E-L34456642524333373422332232122223223333355224537533333342353-27935478A88533233446225233222223227383684QMNHOLEF8EBCMEQPAOFd*L1NISGEI9KAJNJBHDDCLB5LFGEHHHGMBEDEAMACFDODD1676M34235PFCN2KB3465674 * c.47.1.2 PDI-like
[ 431] --316112122212251211111432223131334333444441223453535311211332211-13 1154411111111121111-13113511111331112133243442211111433221112262634434221111114132B1212211111111---2121242322---------------111111111111113222214222122-4511-------1231442------------222111311242222232222223235722332222635112222221661111111111111112111131-1121111112221131121211111121113111111111111122222222222222111111111356294444444748383324423444122121B7321113652221-11113222222222238993222222322332333333-545445465331A666452A655754-53486444444454555555255222121111111111---------------11112215124331-5666743222255794443437474475--442322114341841122222---------11111113211132222221111113111111113333-2211----1-2-222222211-2-22511-1-3----12111--311-1--2111----2111------1-2-1--3333333333-233333333323333333--12----11-111-111111111112--111---1--------------1---------324-3---------------1111113121214444546421434211121111111122124-----1-11111122221111111--14111111------------------1----------2------32453322334111 ----54--211-1--42444534463B1121112112112222222114354B42221111122123311-122111111311111--22542111131141-234-342CIYFONB7895BCCUOAKBO*F-IBS6CDARBDDD9BA46DB7O7NACE64D65345646L7753-33-R---344237423--1-1-3 * b.92.1.3 Hydantoinase (dihydropyrimidinase)
[ 432] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111313-321222----12232--------------2----------------------------------------------------------------------------------------------------------------------------------------------1--------------1-1------------------------------------------1-----1----1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1121----------------------------------------------------------------------------------------------------------1 ----1-4-1-------------------------------------------------------1---------------------------------------------*******cYZUbob*rX*f***1*l*NdWd*YlzmMkZUNpQL*bkegf6A9GwD*121131181----------------------1- * b.22.1.1 TNF-like
[ 433] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------*ctYndUSILMXXX**U*Q**v1*g*OTNJtRYecKURMLjSF*TpYSaFOHOTaB9FAAG9AZ*------------------------ * a.77.1.2 DEATH domain, DD
[ 434] ----1------------1-----11--2-111C9---------42-K1-2711------1--1----- 28r-9----------------------------------1-113-b-----14---------2----11-------112113------22A1-4------67215D214---------------------------11-3-4-125-2--------------11----1--------------31-----33-2222211221111122111-11123114-3-1--11-gY---2221-2222--11----2--1--1----22-----------11---1---111------------------------1---------31-WF11112122228-22-14-nAA153B65-C8K51B-21233131--*-71-----------1----------11--111112-----------------------------------------------------------------------------------------1-------------1111----1111-1-----1---1--3-4--D--811-------1--------------1F-3-----------265--1C--45A591-1------------------------C--3-17457-E414IBJ75BE76764MC4775----21-------1B--C-5HmlHHIHHU9-e9HWuDJSODnMyIIIPIJ-----BAG-C1-11-21-1531-2-13721214-MTYSycpbt*h*--1------------A-------------------1---2-1--5----4-22---1--111-----------2P1-----G3-25--------------------44DE--------3-E--------------------------1---12212-13- ----34-----------21---------------------------------------1------------------------------------------------2-34222333333333243-536I4164G252254344244228--5448422---112-1117-133----1----26112124------- * b.1.14.1 Invasin/intimin cell-adhesion fragments
[ 435] ------------------------------1-------------------11-----1---------- 1-A------------------------------111-----1---1-1-----1---1--221-112521-----------------------111---221574-453------------------------1-22211---3---1-1111111-------1-2---1------------1-------111----------------32221---11122--------41-----------------------------------------------------1--------------------------111---1111-1---1111111-1-1-11-112121--1-----------2---------7-13221--------------1-------------1--------------11-------------3-11-----------------------------------------------------11211132211112111111111231111112123222--111-12221222-122-----211111111---22-52--------1-------1-----111134-------------------------11-----311355434333324333324336246----1----------------------------------------------------------------------------------------------3---------113-3-----------------------11--2222112121111--111-2-21-2-1322311111222113333333111------1-111122--------1-----------------------------1---1---11-2 1112119-7337444159A21112122111111444333333311133448979GFB32222111111111111111111111121111121512111111-1----6H7yaTQUVZPOPQONPlbOTO**V1aNoKQQPXQPSNLQOMVQNSbTPMKPJQOKbFfenQSiHJTC-865O2213532247321378A89 * c.56.5.1 Pancreatic carboxypeptidases
[ 436] 22222212111111121121212222222222222222222222222522442222222222222211 2222222222222222222-22222222222222222222222222222222222222222222222222222222222222222522333323112222222222222-111111-111111343222224224222222222244223322222222222422222222222222222222222233222222222222222222222222222222222224444442322222222222222222222422222222222222222222222222222222422422444242424444444444444422222222223222444444444424224444534332442222222252222222334224222222222422242222222222222222222-2222222222222222222222222222242242442222222222222242242222222222222222222222222222222222222222222222224244224444452522622222222222222242422224222222222222224422222422242224222222222236644342242222222222222222222222232222232222224242222224222222222222222422222-22222222222222222122-2222222222222222222222222222222222222222222222222222222222222222222222222224444242422222222222222222222222224222222222222222222222222222222242222242422222222222222222223222222---1-11--15----2-353425232353227444422222422424222 3334323-D54133333333333333433332333333333333332333333133333333333333233233333233333333333343333333333438BA134275855542233353634624W4-3533223523453331333343734547433338824835435443d23223688C3553332233 * a.69.1.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
[ 437] 11-2--2222322322-2222222311222432222222222222222334432231-1--3112-33 2322322222222223322-22222522222222222255222222311222212222--222223423222222222-221422222222212---111314332332--------------122233322223333432224222222222222222222222222322222222222223333322122222222222222222222222222222222112222222312222222222222222222-------1------------1112-2-------22211111111111-------------222222222-24-22111111121232221---2-21-2322222222221222222--2122322211111423334222222222222222222-22422522222123332232223232642434222223322222222222223221111111111--11111111111111111222622798564445445333344663333-354776882266523344634355333222254233333322243222322222222222-434344333333323233232222223-1211111112222222222543435443333334333333333333-1-4422-11--143433344444444444-4434443444444334436343333434343434444434334332244442-333333333333111411111111124333111213-1111222244444444445244444455444544444212122121222223333333333444444444433442221332222-------------------------------------12--2-2222221 11--223-311-1247543555578754444444444444344444434656865456444444444434454454413444444444446454455554444656-52445832263252423454447a3-3383433323323433334463533326D22232623824322223k22122537A4632233332 * c.8.2.1 LeuD-like
[ 438] 11111-121111111113111121211113111111111121122222--2111------1111--12 12213232222231-1111-1211121111112111121111111321212-212222--1125212454212222221-2-12111222221211---1111111121111111111111111111111121212224311111322-11211-----1--11-2112---1---------2222276-3255555555555555558666665552332424767666453333333333333324222334126525334756657222113344222111121111111111111111111111111113222222223314F6666666563461112116123-2112222122-2--13213-11123111111111211212132212111111111112-111111111321444544555455241112111111111--------1---12221111111111111111111111111111111111-111112111111111111211111-212222211111222211111211112----11-------11121111-11------11--131111121332212-111111222221-1-------11112112261-1112111111111211111111111---1112------45113523443333334-443444334343444344397932242343333333333333362133333--322122211222--111111122221121-111111111111111111111211112----1--1-111---1-111111111-2114222222414411211111111111--12113211111111111-2----1-1112-11222111111---21321546551211 3322434-G66122522445323242422333322222223223332223334G3333443423333634333244524545544311223222232222232544-33367D88AC89C5A86BF7Q7X*B-FBMA998J87CC88788787H6786633994348754J34437555*55556FCVK3B91333221 * c.2.1.5 LDH N-terminal domain-like
[ 439] -------------------------------------------------------------------- 3333333333333333336-33336333333334348444367863333333333333335333646686633336333333333333333333333333333633633333333333333333333333333333333335533366333333333333333333663233333333333336333333C3366666696369969933333366633373333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333334333333333333333336736333333333333333333333333333333333363333333333333333333333333333333333333-33333333333333363333333333333339333333333333333333333333333533333333333333333333333323633333333333333333333333333333333333333333333333636343333333333433333333333363333333333333333333333333333333333333333333333333333333333333333333333333333333333333333-3333333333333333333333333333-33333333333333333333333333333333333333333333333333333333333333333333333333333333333334333333333333333333333333333333363333333333333333333333333333333333333333333333333333333333333333333-33333-333333333333333322243334434343333 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----3---- * d.131.1.1 DNA polymerase III, beta subunit
[ 440] -----------------------------------------------1-------------------- -2------------------------------------------2-2-222-----1-----1------------------2------------------------4-----------------1-------------1--------1------------2H--2--3----------------2------1-111121221332533-4----322111--22222222-----------------------13-22-1---52----11-11--1-111---1-1--------------------------22---222-------------------------------------------------4-1------ClICG--A--1-----5-53348-6334-------C-2-B--d---------2A---3--1-11---------------------------11----------------------7---------SQh***SOELDIA**deWRMGeC*-4------B-----1---J-------1--33-1-1-----------------------------3-------------B--------------------22---------------------------------------------------CCG-EEDDD-C--DE-ED-DCD-CC-CCD-----112C6C-BCCCCCCACA-C-D8BA-9C--16B29CB78BCB------------------S-OXLS--1-1-**G--AA--6-D-----1--------------------------------------WTIFLFFDDDQTJW--1--------------------------------------------------------- 4-----2-1------1------------------------------------------------------------------------------1---------1--15-I--5-1--------1-----41--1-------------------1-1-*22-262--------c--2-4------112---1--D--1- * b.81.3.1 Adhesin YadA, collagen-binding domain
[ 441] ---1-11111111111-111222232222121-----------1--11-1---------------14B 33A2833455622262244-4922654343449658574626364434344564533522689153468942111111---13----1-----111----5-1-53613111111111111111-----------45545---6224131112211---1-122-24351----1-2----253522--1-23333335353444554123353445322322322221214222222222222222222133211111-213-122112111----------------------------------------------------111111111-1-1-------1----3-------11---------1--41-9676222123478A4458888744444444436-5865C8647491455555666533664669575344569222222224443345411111111222222222222122222222365472233135584553333345754443237555A761466658453465592432212121223333323354331211--2124111121131-4--AA89CE3133321333331---------2-1111-542241724473565627A544545AB5791-132-211-11121223241112132311-11112221111221-11123352222344554355434554545111111121433333334333-112222222223143152225241222231223333324232524554446443453354522222222234446333336774465334332333323112-443344--------1-1-----------------------------------22-1 ------2-----2335877544473664444435455434344544555754663453444411-1-1----11-------11111-1-22282211211223122-5I372111322114111112327H1-324121262111-22211223111122-12572-1116337A1335944453635563443311-5 * c.47.1.13 DsbA-like
[ 442] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2---------------------------------------------------------1-------1----------------------------------3--W**y**teOTTalf**U*b**yI*p*GdYPyXiqYFhbSRyNH*ajaif9OG5BDC7QEFhABB8-1---------------------- * g.16.2.1 Plexin repeat
[ 443] ------------------------------------------------------------------2- --1-1-------------------------------------------------------22---------------------------------------1----2------------------------------------6-------------------------1----------------------1-----------------11-1-------1--------------------------------------------------------------------------------------------------------------------------------3---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-1--------3-------------------------------------------------------1--3---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --11--3-----------------------------------------------------------------------------------------------------W-*gti**iUMPMPVW*iThR**o1*cvJTTNgKVdPJUPPIYLFmPpSNch*a1l*Q36345FQ**-----------------------3 * b.29.1.25 MAM domain
[ 444] 11----3111111111-111-1-5-33---21---------------24--------1--1-2-1--- 1552522744732235222-25--47222224634427BD1533-1-1----344231--1174135213------------1-----22222277---213313-2-1---------------22242222422---22---21------------------2------------------32222---1-23333333313333331211123312-2531-1111115--111111111111111---222--22---2-22--222--2-22-----3333-22-----------4444444442244---------4-65191111111515-5662312-8-2---26-993B8I4541--3-28----4441-----46B333278B66534253443434-44644865221-43352226242335141425353421133333333433--238------------12122211--11------15C1-4884966678668888668788884696E9A961388367466892F49354-----2----------1483FM52----------JGH4H46445555439G-----------1-1111111----------35-445524333323644433323351---1---------53643416556664656-56567556755667767777653312-7874777775747447454-2245--422222-22222---1------222-1213---22-23321--1-8997848541B-77775777357676777-------------322222-----6657677331------24221133--------2-2-----------2---------2---31311-3----223 ----333-531---425565554455533333311133333333334422465655344444323222232222322222233333442132533B1111311244-33733212431333121311212B2-1151141111521111113111411413136355433B5561--1-----31---25--223221- * c.124.1.2 CoA transferase alpha subunit-like
[ 445] 22121222222222222221222233332333222222222222212222222222222222122233 2222222222222222222-22222222222222222222233322222222222222223322222222222222222222222222333323331--222222222211111111111111122222222222222222222222222222222222222222222222222222222222222233222222222223233323322222223322222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222322233224221222222221222222222222222222222222222222222-22222222222122222222222222222222222222222222222222222221111111111221111111111111111122222233233333333333333333333333333334333333333333333333333332333333333223333223232222222222222222232333322242222222222222222222222222223333333333333333333333333333331-3333311111133333333333333333-33233333333333333333333333333333333333333333333333331333333333333113333333333333333323333333333333222222222233333333333333333333333333333333333333333333333333333333322312122222222222211222222-112111111112111111122222222221212 3333443-B4435532323222221223322222223232232222222122232222222233344434434334443434444434415331223333323444335533532233231342542638N4-3542323323432313332241332436433242522423226556j66545648A2866755547 * d.15.10.2 G domain-linked domain
[ 446] 11----1122222223-13213124C8331451-1--------11-212-211----1--11-12111 2123522444413345544-474466444446888959CB23243143-11-444123--55622564546-------1113311-11211112221---113342322--------------2111111111-13225511131332222222222211222221222111211111111113222--14343333332314333321133233442423141-111--5-2444234334334341331211111111111----111--1111111111---111222222222221112111111111122---222112112111111111121221111111111111-341112-312111111-214466712222435678535446633223212223-46536352456234436445334555454343232243433333333533443331111---1----1111111111--11111366A332221144444533333443445433344456771433334323444221234442232221211122234327461121123111111111222245447443---1----------------2--11442224533223243333246222153561551--442211-11122222222222222222-222232222222222222222322222223332322233233342222222212222222222222212222222222433322222222221222234444433342433332232243233422222222222232223222222245622223222222212223122121---------2121111----1--------1-1-----1--111-11134-3 22--225-8432356353366747776233333443322223222243443344233244442111121111111332321111111122515231223121236412A37755432434-53587265De8185D34455456544432523535244DC33C331534632631214R4432264893BF3533334 * d.157.1.2 Glyoxalase II (hydroxyacylglutathione hydrolase)
[ 447] 22222222222222222222222222222222222222222222222222222222222222222222 2222222222222222222-222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222212222222222211211222222222222-22222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 45222242D64233322333333332333333333333333333333333334333323333323333234223344244333333555343233333333436672452688556342553737A1G3Ai8-55G3564444853425154343645545355443A56444656354k54346DGMS3EA2223223 * c.55.4.1 Ribosomal protein L18 and S11
[ 448] 22222222222222222222222222222222222222222222222222222222222222222222 2222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222221222222222222222222222222222222222222222222222222222-222222222221122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 22222222A44234444442444443244344444435443444443444444434444322444466446446466666644444666454444444444546872262424224224F7562AM29-6O6-249-34C422426244-22-24422222A3424-428622235464*44446CAIN4962222224 * d.141.1.1 Ribosomal protein L6
[ 449] --1----12222222-1-------------1----11111111-------1----------111---- -1---111111111-----------1-----------111------------111111-----------------------1------1112--111---2231112-2111111111111111-----1--111--------2-11------1--1111111------1111121211111-1-11---11222222222223222322222222211142223222221224433353344443322423111111111-122111111121-23422231112112222233232322222222222222331112223211123333333333-2111222-1-31--11-67121---1----2-11-2----1-------------------------------------------11-----------121111-----11-------------------1111111--------1----------11----12-122222221----112211111121222212211111-1-221-21111-1-----------11--2322--3-14--332-1221212111--1----3211--111113-1-------13313--21111-212-223323242221131221222-----121122233221323333333333-33333333233333333332222222233333333333333333323333322222222222222112311111---1-121----1-1---------1111112---1-1111111-111111111---------3---311111-1-1211111111111111--32441122--------2-31111---12--------1-----------------1--1 21--776-A54434745635555445546545445454344446565477579E5576676775777554695657767A454555555654555434454649BE1478JHKHKGPEEEEFGEOOCXEv*N1SJjBBCBJCFHBAFGB8G8AREEEFG9ECDJX73533648C52756W75655349354576GDCD4 * c.46.1.1 Cell cycle control phosphatase, catalytic domain
[ 450] -----------------------------1----1-------------------------------11 ----1---111--11------211-3------4121-1--11--231-121-1111-1----1-1-3211-42223331133--------------7---1---313--------------------11---1--111-----1-21111151---1------1--1112--------------1-----1-21111141323121311-222-132--1----21124333-33323434333343------4-1112-323----111-2------66615541--22222221222-------------411---1111----11111111111----------11--21--11-----------------1---111111-3221111--11-22222222224-11211122----211211-11---24--1-3-1-21-----------------------------111111122111111--11-1---------1--3-12--------1-111-11---------3--1----13-1--3---------------1-2--1-1-----1-----112--11-1----55---2--2-3-----1---------1-------1-33-1-1-----22--------1-11----1---------2-22-1---------------1-----------------11F82-2--------------2-------1-111111111111---1-----22221-3-1---1-----------1113112-11-2114143522---1-1-2-------------222222222242166864354----------11-------------------------------------------------11- 3332F9A-VEA5GHIFBJICDGDSLKLCC65779C97989899A9AFEEGFKPTHHFFDCDEN46724243254733253255546463GgQBMSY11259CDMQM24iHT2234233313223332226O21222-411222211423-211124332211532474339Nh837QH8VAAAadnii*EqqHPHGKJA * c.69.1.17 Fungal lipases
[ 451] -----------------------1--------11----1-11--61-4-1523-1-1-11-------- ----1-------2----------------------------1-1-------------2-------------22222222------1--4563-434---111--2-7-1-------------------11111-111111--------------------------11--------------------------------------------------------111111---22222222222222111--14232231446222222211-1211111111111111111111111122333333333331111111111---11----------12---------22-13-------1--------11---2---------------------1----------------------------------1----1--1-1-11-1------------1------------------------------------1--------------------1--------------------------------1-------------------531---1--1-----1--2-1-11-----1-3------------------------------1------1----------------------------------11----------------------------------1-----------------------------------------------------2222----------------------------------------------111--------------------------1111-3321111----221111---------1-------131-13-----12--1----1--1------2-- GB45SUA-SACR---11112---1112111111111-------111111111211111211122-1111-221-112123211111---1311118---1211211-AScpLbHOhZDHEHEEKYRDPFY*N-LIXHCGGKHEGJCEHGJFF9MLHFJUAFDCKMuJTDGFfXg9-IIA*9A9J8Cmyq1li9ETPUPb * d.3.1.1 Papain-like
[ 452] 111-111111111111-111111-22232222-----------11--1--211-1111111---1111 123-11111111-1----------------------1-------11--111-211-11----1--1------------2---2--1--222314332--2222131121111111111111112-----------33333---71111111122112222221112111222222122222264533--2433878787986888788544432888444444433333374522222222222222222223121231111122--3322123312122222122112222222222222222222222222331123332-23-2-------2-214112222311334111-2311-121--223-2321-32223111-1322222222222222222222222-33333333232122222222222222222343333333422222222344332321111111111111111112-1-1111111-2-12-111111111112111111112222121111111111112211111131111111115111111111121212---1-1--1-----1211111-1665694-21111111111111111111111111115423123232268777745777476674651-31111------33222332222222222-2222222222222222222333223112222222222222222422222221132222232222211131111122221111211111111111111122232211121211111121111221111212122221134433333344444554444435522221111222222111111113152122--11111-111111111122233232111111522 23--223-K93-1145G22-223444222223222222222222222225473422222222321421122232322122222222111252G2222221221333-4B4f8A767E9998ADABBBC8Fr71C7K57657A5C848B788A6EA77667BL6BAEF9D9I33E43565k55534538834B5683335 * d.92.1.5 Neurolysin-like
[ 453] 22232223333333322223234232223222222232222222222223222222444222223222 ------------------------------------------------------1----------------------------1-------------------------------------------------1-----------2---11-1-----------------------------------1------------1---------------11---------------------------------------------------------------------------------------------------------------------------1-----------------------------------------1---------1--------------------------------------------------------------------------------------------------------1--------------------------------------------------1-----------------------------------------------------------------------------------------------------------------1-------------1-----------------------------------------------------------------------------------------------------------------------1---------------------------------------------1-11-------------------------1---1------------------------1----------1- 8346888-N8AA899968877778666786778778688767777777688777679776667887775775767675676677687677E66866878855688A-AA8ROOGJLZMIGKQLHgVNlJ**e4xU*DSIIiPLYOASHPFgL8eKMDLK75579A969ACF88875A85U787679A7F9C85679995 * a.2.5.1 Prefoldin
[ 454] -------------------------227----111--------1------1----3--2-----1--- 5222I----------------1--2------11-------5-11--3-1-1-111--1--23114-89C82----1------------22C2--------5---7-11-------------------1-------11111---41--1------------11-----12--------1---------11-3-243434334244544424441544313432--22222268--------------------3--1--1----------------111----111--------------1111111111111-----------2223555555544-51111---814--4113133221122-1214----2--1--------------------------------------2------------------22---------------------------11-----------1------3------------11-1-----21111211111----111111221--------2--1---------------5---------------1--1----1------------------53--1--------------------1-----221--5------22222-11111-111--3-------------11112--1--11111-1--1----1----1-1111111-1--45-11--1111112111-14-------1-----1----111-----22-122221-8----------------------------4122113111-----111745454344-1333444438425622111111111111----223333----------1----1-------------------------------11- 12--AG5-51--55AAAIAJIMEHFHL779987HMCEAC9999554AEKYKMQUFKFHACAB325122-42231422222245464111BJAA9FB44447G4G8F-3E2OBF89AA8694557ID9H8T*A-G9G7697958C783846879E784963338DRYNPaasxjC6-8411111727YiVBBH2L43347 * c.1.8.5 Type II chitinase
[ 455] 11----2-3434323---111---2111--11----------------------------2111---- 2242511111112132322-211153222222444435754435233322225463351175425394443----------16---1-1111-1--22234444644443333333333333321--1----14-5663311-2411111111111111111111311212111211211113323311-42444444444344444446445444447634542333224323333333333333334443221-22-21-1112221121111332111111112211111-111111111111111111211111111111---1111111-1-1111------1--2------1-------21213-14-2522322222334234233324255554454455-222223224522344332843364443234363333434333333332442232222222222221122222222222222222136D4113233444454322223336222214433343211223121111135321122---1211221221112322-2-2-1--1-----323234422222233-3--------------------1-11122222222332233322233222223222234--1321111111131111221112122211-1111121111121111113233212312222222222222222111111111122122222222211133333333331131211122111111111122222121124244442323233321211111111111-1112111112212233222223331111--1-222223----------111111-1-11111111111111---------1-2-2324 33--444-B44-4442333333344443333333333333333333333433543333333332222222222222212222223222245434463234422545157498967674565456BB454Jl6278E77667556516555644A556675BN45548M84T54644554*4544587HA3985676554 * c.36.1.7 Branched-chain alpha-keto acid dehydrogenase Pyr module
[ 456] 1-111122222222221211221132232141111111111112321111222-32332341212-11 1262422222223126622-241146222224444422332111112212223232121132113233541111111111213111113333-3221--121212122111111111111111122112111221333221112222322211111111111111222221111111111111111122222244444444244444434223244423445222222225322222222222222222222322323322222222331212323331122122222222222222222222222222222232222222213224555656635326114444112213222278331121331111231211211311111112322221113122332332336-222222337F11988553667665211232874444565222222222112221111111111111111111111111111111513321233333333332222244363333323651322111111211111212311111114122222221111112332333312222223332324321121213211111222221-11-111-11111111112312423243111122421223143234--12111------31311312222222222-22222222222222222221211111112111111111111112222111111224234324333---1111111111114721111111111-1111322241111211223224222533512321111111112111111111222111222222222222211-211111111111111121-1111-11111111111111111111221113111-112 1111443-952144555535444555566444444435443345446656547844444444454333344344433323244445334685556744444338771455N774548243344485364Db4-852332362462244325227435235983446496AD53933452O5433345454473243455 * c.55.2.1 Creatinase/prolidase N-terminal domain
[ 457] 1113111222222222-434444-2--4114311-23121112-123222424-121-1--1--1-22 1332822322232122211-13111211111123332212364624454331111122117552735442331113112333211211112113113--12453423221111111111111122131131113333323111836445446232232224342337695222222222222322111315342233334343453342433223336449422222222EE21111111111111111111312332322122211333221112222221111422111111211122211121131112222222322228423222122352422221332342211134233311618113332111414433422223337532333222333333333333-445448444632344234433344234563242222332222222222223333322111111111111111111111112222252532243323222232333322274444433333432123334333322323233222333322222225624231274425312433212211112329999BC252111122222212111111121112224434452353567667655667566565452-2567422-11145433424564444544-544444444454434444444433242445455544555554544444444323333333333331124333336666647454443332222223332222223233546666565657587576634423433454546444446455544544444442333224155223311111111121------------1------------12122131221323 1---112-523-4442---112-8364-------31----------1----23211112222---------------------------------1111--2---1--72------422111---12--11------212-1---1--1--2----------29-------2-12-3224---1-9245-42-1211-9 * d.142.1.1 ATP-binding domain of peptide synthetases
[ 458] -----------------------1--------------1----11112---1--------1------- -32-32222225523------2--11-----121-165AA-12411---11--21--1--22323134341-----------2--11---------1--112-14-21-11111111112122-11122311113544-----3-621111-1122---12111123314-1-----21-112-2-----1-232323132-222322213322224-1-1111----113--3333333333333335514-4224422323455545332221-11111----222-------1----------------1--111-----11112222222323----2----111-11------11111--111--22--4------1----454-1-12223----------1-22-222-1-13--11-121122--1-2-12---1--31311111111------12----1-----11--11-11111111------2-11-----1342412344333--4336-345-2-22--1141331212245-1-8----2--------11122422251131-21121-2-1-31311333366---1-----------1111-111--1---3311221-32321211445111-6132134--112-2---------1--------1-1---1---------11----1---1---321--------------------------1--------------3-----4554154------1----------44444262352144241132311112---1---------33352222222322443323332211-1----776677-----------------1---1--------------2113221222-21- 4C23856-D33644AEDFBFCEAFEECA89AB9FD8AA5889B766FEFTHDLDDIEXCEBC679686497667678668854787222567DAA5544768787A-7MG8A543445323643553467I3-36634435553323333453952348336564537764JJ6649B9U77686KSSeCZG69HMON9 * c.69.1.18 Bacterial lipase
[ 459] ----------------1----------1-------------------11--------1----11---- 3BN1p--1---1--33533-35--46232222635362752UCb46-22222355-12--GB61L9EJLP3-111---11132--1--11-1--12---1---221151----------------1--1-13231CCEGJ---K23-231133223-2212-22394283------------74511-1--1----------11-----1-----1--112--111111-43----------------------1--------------------------1---1-------------11111111111111----------2--1-----------------------3-2--65--1112-------2-9-34335------165532-3244244444444444---7--3-3361-344231442344341344444346212222222222542173211----------------------------24731242243553546344444364444434325663135433122272515414552212211-----56832215642121342442-325752354FDBFNd-2--1-------1---11-11--1---54132-33322211-11-22--111----11---13426------11111212221211121-2222111112211222222221221212121212422212112111111111-233333133132--11111-132222272-111---11-111---111112-2214377574525922225354----------2332222224212256867656682313--5-111111---------1----------------------------2--11121-33- ----1-8-824262354759558EBC622445543325334242214578468B6A296456312-1---1-1---1--11-1--13121764A2I24242-1122-4T-Q5851725333642992A-CO4-2653-2224492162121224134343431283-45483-7427FBM4757C5KC854r9736429 * a.118.8.3 BTAD-like
[ 460] 3311221122222224222121-21111--12111--------2111211333-1--11--222--12 124-422222222251233-33223643343333434698242453232221314112--22514248652----------112132222231311---13-425331311111111111111111212211223-1-221112142222222222222223232223322222222222223443311131122222212122222212111122113211-12222224321111111111111111113-------1-1-111111-1-11------------11---------------------------111----1321111111111111211----2-1---111111222141-12--22--112222211111224642223222222222222223-4434225342314555234873323234344433445341111111132224222---2111111--1111111111111----13352222212244463322223333222222442223413332232223242353232322322222222222222253623311212211333322312222235232333322224353555555553434452333543354322232222223222222261-13334------33332442333433343-32233333343333323333333333244444444444343444333333321422232233333111211111333334574111111111111111222222334342666655545766546554223233221222222222342331122222323-111--3266224411-1111122--------------------------16222111111323 ----544-211-1114533355383624412112222222222323445645553414344332312333232332212232224222222351225344453532-3A6A59454C547465585786Lg7-B7D435765557467656578556484334564669D822831542g1125234543355221129 * d.160.1.1 Nitrilase
[ 461] --------------------------------------------------1----------------- ------------------1-1---1-111111----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------1144----------------------------------------------------------1-1111111--------111-----------------------------------------------11111--------------------------------------------------1------------------------------------------------------------------------------------------------------1-------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1--1------- 3311HGA-qN85GGWGKLFMJKMTPPLIJEGFFILEEFDDCEEBFHFGGKLLUMIJHHGGGGABA6994955B8A4535588899A475IZIKHIFDDDBEBDVUS1AhFG8B7A8886887D8HI6G7KnD1G9G5856E79D958884G83F8F9D84767FB79DCFI9AGD6B9H*JHG5AJBKFIBAFJ9ABBN * d.120.1.1 Cytochrome b5
[ 462] 22121221111111121111111211111211222221111111111421332221212221112121 2222222222222222122-22222222222222222222222222222222222222222222322222222222222222223422222222--22222222222221111111111----343222224224222222222244222222222222222422222222222222222221111133222222222222222222223222222222222224444442222222222222222232222322222222222222222222222222222222322322333232323332333333333322222222222222333333343423223333433242442222222232221122343224222222222422232222222222222222222-2222222222222222222222222222243242442222222222222242242222222222222222222222222222222222222222222222224244224444442422622222222222222242422224222222222222224422222422342224222222222236633332242222222222222222222222232222222222224242222224222222222222222322222-22222222222222222122-22222222222222222222222222222222222222222222222222222222222222222222222222244442424222222222222222222222222242222222222222222222222222222222422222424222222222222222222222222221-111111-24----2-343323232243227433322222322324222 3323223-B54133333153333333433332333323332323332233333233323333333333233333333233333333333343323533333328B9134275855423233343633736J4-3533223613353311333241933445634334944A36245444d22222669B3553343343 * b.49.1.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
[ 463] 22121122333333331122222411111121--1-1-------1-225-1111111111----21-- -231-1---------11--------1----------2111111111111---111111--111-2111111-----------322111--------------1111-21--------------------------33333111121132221222211111121122222------------2112211--111111111111111111111111111111111------111111111111111111--11----------------------------------------------------------------------1------------------------------111111321121--11---2113221-----122221111122111111111112-24423323151-211122222211211-12314444326--------2-----12-----------------------------11-3--34333333434155653312555544442323312222232221351412221111321111111-11122-2342121111111112111112-22124233--------------------1--111111-23-2222111111-1-111-1111--1---1312-------------------------------------------111--11-----------------1------------------------------111111312----------------------1111133332534224221111---------2111-11111111111121111111------1-222222------------------------------------11--1-1---11-- 34334431C441447344444445434444444444444454444444444444444444445555553655536555655666663338874679777576678726Y5IEHFIBGGFFEBDGYPFYH**K4aHRAEEAGEEH98EKJ9JG7LDEBCB77A698E8C698CEA74EEAn9A8CCBDIE4EBC9A9B97 * c.42.1.2 Histone deacetylase, HDAC
[ 464] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------F-----2334752644444444434444444444344333444444454444434333333323443335424433333344455475746774135ABE24-1nns*y*ZNLMJSXP*pKvR**v1vg*JPFIeOVgYEaKNDTKDpYbTYjTWTVgVHIUGNV9RYI1----111----2-5----1-11- * a.4.5.14 Forkhead DNA-binding domain
[ 465] -----1-------------11-1-B1153174-----------111-1---------1---------- 1-51D21456A21197633-38--4M333333C89AIJph242C5B512212MKQ643--5492BETDJE21111444----72-322-----1--------------1--------------------------22211----4--1----------------1-----------------6732411-41122222233232222253331123113463--------62--------------------1-1-11----------1-----------------------------------------------------13--2-----------2--1--------2----11-12-1325-1-2------6111-----21G88--96656277777775769-125--814H62-988A557877A8D731-37E223357611111111311--112-------------------------------8A--6jbLPHJJPJGADCC8LLSPDDDD5DTEbRfdR11CC794A76L8E6OL23212--21111111----524-111-111-2-----354264711-----1-----1-11--1---------------11--2-123-4---------11--------------1-1------43542429557977767-5785868686587887888898441327376757777767666854444444-211221122222----------------671112-31-1-121117785738464719868297A347863555111111111----3-----12124--22222121-------------------------------------------------------12111---- ------------------------1-------------------------------------------------------------------------------------------------------------------------------------3-----------------------------2---------- * a.4.5.33 Transcriptional regulator IclR, N-terminal domain
[ 466] ------------------11111-------1-------------1-2--34-1----11-----1-5- -1--1----------------1--1--------------------11-----1-1--1------111--11----111--1------1------------------111--------------1---1-1----------111---111---11-----------2111------------------11---------------------11---------2-----------------------------------------------------------------------------------------------------1---------------11----2-3--2----111----1----1----1----------------------------------------------------1--111----------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-17-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1------- -----------1---------------11----111-------111-----1--------------------------------------------------------2C9WebPf*bXcbhml*tl*b**j-xe*YdZaqZU*cfagTYieP*aVUTQ985G586hiPeFFH43-11-----3-4A3A-C1-1----- * e.1.1.1 Serpins
[ 467] 11113211-------13111111-211121-1-------------11-1-----11-222-111---- -122221222222122233-31113133333322221211-3334A431331223434--3442428888311111111-1-3--1-12361-3-----1412152826--------------111-1111111111111---12332-11-11--------1--12223------------323-11112245555555556555546355335642224222222222573555545445555446344433323322323441133322532322-111---122111112112111111111111111211---111213-213333333233-2--222141-1-211------1-11--111-1414-243321111122313111111221-111111111-11211212232-7776556775331134331111113231111111111111232------------------------------21212111112232222333322214433322124223--222212223132411111---21-------11212252212111-23111-1-1---12-222221-1---------11---------1-11---22-223122222333323222222111212---21-1------22232112222222222-222222222222222222233333223222222222222222232212222--455555555555--11111112222122211-1111-1121-11122222111212244442322311122454222222222-211422222323221144344444------1-222222---1-111212--------11--2111111211---1111111111---- 112243--9431345879957876746775756555999979965555237889346543334424343333443331333233332224527452533343231312548DD87EB8984767B78F7Ge71A7B6696C76B557A68875H7878951646454A12158683972F23244BHIH6K7422232- * c.1.18.3 Glycerophosphoryl diester phosphodiesterase
[ 468] ------1112223122-2------1-------------1---1-D--1-224-----1---111--92 CAV-21-----2-31231---6--35-----2456515941--35511-33121312---132-517453------------1--1-198fY-7-----2C-38JAR4F-----------------3------3-33326-2-522-6534-11---11412-2-95591------------423-------2-----111-11-1112111-1111-2--111------12-11111111111111-1111------------------------------------------------------------------------1-2---------2----12221-3--1---------------------6-A6447-----41G88---2211122222221324-766583896A4-677353575567211443222222525222222224554-131-----------------------------1-3453-2--634454447886337B8776-463E2141--6545172273428C11212-------------112-2A11-11---2----114-236--22219E-4---1-11111----------1--------17142282132214462532335-2136---2--1------1222122------------------------------344-2-1-11111111111111114------------------------311111-----18351111-1------11111111-211-1733231368423522647----------123-333332412265FKHKICBF3222--1-222311--------3---------------------------------1----I-1 11-1244-533---18B853485D5D244233311-111111111174389ADD43742454111211111-21111111211111-11192B1824554323--2-2IY*8653464343431253559M4-66753233532324542242348536DB72E93997C54T65-323E12145GECG5JB53C9996 * b.68.6.1 SGL-like
[ 469] -----------------------------1------------------12131----1---------- 124-5----------------1-----------1-1-121-P9M---------1------1-1-2-13841---------11--------21--21---1---11-------------------32-261--D27-11-------A1R398611---------11154B1---------------------------------11-1------1----------------1------1--------------1--------------------1----------------------------------------------------2-------1--1---1-----2---1---21---1---------1-1-3211------2--24-11111112212221212--61-1121---1------22---1---611--111------------------1--------------------------------1-1-1-1---1-----1----1--------1--1--------13-121--22--119---------------1-44-212------------2-33222---4--A21------------------------7-1----112--------33--------2--11---1------------1------1--1------------1--------------1-----1-111--1------------------1--11-1212-------------1---------------1-----------------1---------2---1---------1----------1--1--1--1--------------------------1--------------------------------------2-- ----1-7----------------------------------------------------------------------------------------------------6*-*LOLOVUGFGGHRIZTFdG**Q2TPZKHIEPHJORHKGJHODHKJVTLVC79G**9CGGGH36MG16721--1--F32*-*1--8MFF3 * c.23.2.1 Toll/Interleukin receptor TIR domain
[ 470] -----1-----------1------1--1-51--------1----1----14232---11--------- 356-B21-112---43311-122214111111233332511785-2-11---475-11--2333222BC93-222----2233-31351323-5112--1523-4741511111111111111------121-1-1222311133633433133--1-----1-124452------1-----47411222557DCDCDCDG9DCDDED677796CDE647A634111112FF122222222222222--12-2-2-11-1---11--1111----34422122223221111111111122222222222222233312222356DD88888779896B9989A9D85-183374667653376522432425143221-----12A765346766622122212114-32622523362-655366456644541-1-1--1-1122--------1----5-111----------1112-1---111111111-2421345317669672322233733333135435334-2665231211333221172---31-------3123433111212325233424533554126416452313222-1-1---2-------131113322-144511131222212111111111123---3222-------1112213443333363-433422324443233333333322---3233333323333333322332232-333233233333---311111232221321111111---------3333312---2422221564-22221233---------1---22212211-1155322223334444--3-113344--------1------1-----------------------21111213122 --11--------TNC13A65444353333222255533233333225434786788A55555111111112111122222111111---4353H8A44455H6SHY13415-------------------------------------------------------3-----------------11-1-8-1--31112 * c.6.2.3 NodB-like polysaccharide deacetylase
[ 471] 1-----49C66A9E93-12411--4112-123-----1-----21-111--2------1--12-1--- 21-2A324113222J7854-5733E755555678A976B946A72233122144433311457176687721222222--1-41111111-1----1--1332162213111111111111112-----------11111---2444343341122211114241133521111111111113433311-41111111112112112213111211217511411111114111111111111111111211111-11-311111111111111111122222221111111111111122222222222221111111111---111111111111-1--11111--113------------------1114-14126111113477B7216545611111111112-322-572-3264311133333322291333442-22134333333336443323211111111111111111111111111111122341455468AAAAB98999777A999877ECABGDF11FE76G26266548834311313212111111416A93-----1-------1212----1222427L141112111111112111111111123441121321111411111211211111112131-111-311-11122121224222422344-254422242522222422454522332222122222223221242222222112223222332221112111111111342232221211111-11113445421111621111341223644311111111111121111111111121122332323321111111121112211111-1-11111111---11-11111-11111--------1111111-4 2422311-624-22211111111111111111111111121111111111111111111111111111112211122223122212112432123142222113121143-334633332223226394DU3164623332123132234233432224113121234339137-2453q44354A9BD1DE3342333 * a.25.1.2 Ribonucleotide reductase-like
[ 472] 11111-----------121111121112111-------------1111-------------211--11 5571P23233313122222-231147232224333327A84333BEB2766798821A1156A6D89IJD6322276621113-1111215117-1---11-1122313--------------112122212222344551117232222221122222222122244421211111211115522265131322222243223222366445322234516227888855813322222223332221222344123143-39822535374222353334555322655677665664444444444444434333544422-482222222223232213343123-422-122--115-1276521222129553-----42411221-1--133333333333-222232223721D66CBA5BDD791321224254552321111111122242122-----------------------------122212-----2222223111122222222122221221--11131111-22143--22111211111111111122111-1111111111121312111111113213---------1-1-1111111-----116782125-1243444411122211121114--11112------66964536558677755-5666778575576556556676432236666666666666666644555551-666666646666---------11111-122222122-22222343----------331111111111111222253353543323445444442233335443442332222--1-11111111-111-1--3----3---1-1--111111-11---25432575861222 ----221-21-1-1----1-11112111111111111111-11111--111111---1----1--1111-11-11111111------11----1--11111-1----1C34122231111-122542215J2-227--11121211111-111322212----211-----1-211112A121-2232412111C9894 * c.55.1.7 Glucokinase
[ 473] 22-1-144345444541133321331111122----------------13221----1--12113-11 125451-1222-3144455-543367656664444449E8167532121111143311--55724794532--------1-141111111---1------211121212---------------2222222221288866---232322332223333223122232222-21----2--1-22243--131122222222223222352111122234413--------21-----------------------1111----11--11------------------------------------------------------4-121111111212-122211131-1-1--2-461121--42--1--1-322111311111349773366675544444443445-66756C5947416446569657666532155554674552222222242232337-----------------------------219711666676668675556666A856665596978761344488544868575446322135222222244396515834345453555-344132222665636232--112211212222222221111144211131414122222212322222224232---5433------21111113222323333-233333333323333333123211111111111111111111121122222--111111111111---1--111-11142433111111-111111111111111242425555464434445333331112311111112222221122222222222232222112-331133--------1-1--------------------------11---2---321- ----322-741-2322475542445633333334333444344334554468EB4434344423314334224243313324444312147442213332321433-35673335443213333843438I5-2261341323422234332133342347433322425335442333Y3332233193333377652 * d.58.32.1 Vanillyl-alcohol oxidase-like
[ 474] ------------------111--1222223221111111111211111111111-----------122 1121333444422222222-2211222222223222425413323233222322232222232253552422111211121122222222221212-112232332334--------------122222222222222221113232222221122222222222211112222222222222222221-3245555555545555553344445553332322333333322333332333333333323311-11112-1-11--11-2-1112222222222211222222222222222222222222211222111123234111121122221224222112-22112233211111222112-11222333411111334332233343233343333226-44444433363-6445454354653325345565664452222222222213135----------111111111111111----23222345554455455633333332444434534433322335332222335423323323222222222222344224233432343332122222222443423232233322222322222222222222222233232232222222224222232332331113333------22442222222222222-2222222222222222222222442432222222222222222222222222-22222222222222-2111112222333322221221222222222222222222222222222222222222222212222231222222222222222222222222212332-222222----------1-------------------------12111111112223 11--113-52323335573755669753333333434443433333445877D86544434432222233322233313323333322226453543233424555-3F322422443242121932624Q2-3351424522211331121111112322123112111922313543X33363E9DA8D86652433 * e.17.1.1 D-aminoacid aminotransferase-like PLP-dependent enzymes
[ 475] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------2--11-------------------------1--------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1-1---------------------------------------------------------------------------------------------------------------------------------------------------- 662297I-qMMEAED3342333333343333335322333233233233333333433344422222212224232212222221222224335333332133444-AJNsRVPLOUJQVQSXVvmPbQ**b4cX*JURUYNSYNFQNPKYMEaJMKOLMUSFTOEAUHRP7BVH1GEDo56375G9C63AA26KLFKK * c.10.2.3 mRNA export factor tap
[ 476] -------------------------------------------1--1--------------------- --1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------1------------------------------1-1--------------------------------------------------------------------- 4643BEF-H6B4OCB64227466546544455548645245343753332435324325333323333113421242253233322356355443622221213581AxCkOPOJSKLGDJMMOmZNiE**Y7gRfHJFJWMJVNGPPPJUGDhJRIKPKOK7PDD6BFGC9HSJ5JUGY7A6JFYQOd2IQB9IWRUQ * a.118.1.21 HspBP1 domain
[ 477] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----L------EA-1316-------8---------2-----1---1-----7*---j---1-----1---1--1111-1---------TB437K*---1-*-11---A-5XYD6t77444695CC7I9T*G8FDF9798AB8F54A837G68B633DBbzl**3vB41-39KI3-Hc2-1-22-7*a*DQA--**X*3 * c.55.3.12 Hermes transposase-like
[ 478] 11111111-1-111112111111111111111111111111111111111111111111111111111 1221211111111122222-22112222222222222222222222121111222111112231222222111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111212222222222222222222222222221132132222222222222222222222222222111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111112111111111111111111111111111111111111111111111111111111111-111131111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1121111111111121111112112211111111111111111111111111111111111222111222222221111111111111121222222211111112221122112222222222222222222221-1111211111122222222221222222-22222222222222222222222222222222222222322222222222221233323333222111111111111111112111111111111111111111111111111111111211111111111111111222222222222222222222222111111111111111111111111111112-112111111112111111111111111111111 6433774-K763336568855656466665666665665676656687556566566656667555554556544762665555557768D76A8j6787557B6844J5KAB89BD7665366AB8F8S*A2D7E567476786486547868687786586A98677A934F44666Q67575I7C98BA7798696 * c.120.1.2 5' to 3' exonuclease catalytic domain
[ 479] 112-1-------------------111---2-------------21---12-1-1111112------1 -12-12213332312--11-11--1211111-12221364-1-11121-111345331--11--216122-1---1---222-1-1--1112-2111--13112412122222222222222222----1---11-------------2---------1------1111--1-----1----122------145575655656666664255546653265422------41322222222222222322254-1-11-1111111112211------11111112---1111-11---1111111111111111111111--24145555555556-311544423-74-2---2112-1-3--112--323-133341111131953---2111-----------1-3364373512-232211132111142111--3-------21222222-11112-122411111111112111221111112122-224314----C8879B445532257545534533356512445113224212421111111351111111111--3--2-2--1223---2111---1-12212311-12332333331---------12-1---772322331325777755B777676B8697---1---------74444544554444444-5434544454545444445555663325645555555455555444354441-5444444444441111-----333311-232221211222211128888838223424454567826689333222222222214559454437566533333333333333---711111122222222321----1-1-1--------2------------------1-2 -------------1111111-------112111----------1------11111211----------------------------------1----------2-1--81AFMHHEB89869A9GI5D9Kx7-C8H598AAB7787899A793HBAB7958E2G812534C77B3-1117---222--21-42-IBEC- * f.49.1.1 Proton glutamate symport protein
[ 480] --------1--1111----------------------------------------------------- -------------------------------------------------------------------------------------------------------1----------------------------------11-----112-331-1--11-----11----1-1--1-1-1--1-------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111111111111111111111111111-1111111111111111111111111-11-11-1-11111--------1----11111111111---1---1--1------11111--1-----------------------------------1----------12-1----1-1-----------------------------------1--1---------------------------------122-----1-----------------------------1-----------------------------------------------------------------------------------------------------------1---------------111111----1-1111-111---11-111---------------------------1-11------------------------------------------------------------------- 4355IGG1SBA5AA967766666676666666666667765576667777667777777777877787278778788288797788BA978777778988675C9D4DOKRKNMMIQILHJIIJWSKNMq*J1PFTIGKJGIIICGILIKPIGQKMLHDCQbCFEJIGBCPDJGA6BBAv88788BDDJ7FEACIKJJG * d.144.1.4 Phoshoinositide 3-kinase (PI3K), catalytic domain
[ 481] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- A999FFE-R9A3CDEABBCCCCCBBCCBBAB9BBBCBCACCCCCCCC9ABBBBA9ABAAAAAB7968767659B96646679996999ADIBBDBGCBCEAACEDG4DECQHPFGMA9AA7CDANJ8NAZ*I2IGR87CBFCEIC8CE8AFB8IBFFFDHGKCEFFAHDISEFEE8CDC*FCDDEVLaWBNECDIEEG8 * a.4.5.47 PCI domain (PINT motif)
[ 482] --2-1-1-1111112122------32234521-12---------1-21-232--2223521---11-- 358-4-1211121212344-44113244344343332334164522412554135321--75217545654111121121212-1---1211-11----2611131222111111111111112443353444242222211124321511-43552232322-43657424221123122343211212122--1-11---11-1221111121--1--3-4322222125---------------211--43513412322773333332321211222122211122222212222-------------122---222211133111111121214221--17-131253-1---1--211-2111--12134222111116287B3212447344334333334-55664454383-2334553575441-12233424223133333333322222254111-----11----------------1---11-13222136775767455566564345455673333--22412131142241112-223411213222-1213-211111342312221423233344213246212--2-1111121-1111111-1-32--4474242-24311113-1-11121--1313--12-21------44233435445545455-5555566555554555445455573435434343442333343324333343-555555545555----11111112111133222323122222333433342---15233334234132223443111111111212333333355733554454433311112-22331111----------1-1--------11----1----1111-32--111113741 ----121-632211324241334532333333355333222223223343253623433232122121-2321122323322212222247544343212232221-3H-41122122111-12321424H2-224112-1122122-2-12143113144112114711111413C9Av767D4678B4A75653128 * c.108.1.6 beta-Phosphoglucomutase-like
[ 483] 2233433444443444434443322321111222-3334343422321223325111211112-1232 ---1211---1---111----1---1------213113111121--1112---1--1---222-4-1332--1--1----11-11---11-1----------1-1-1----------------------------1--21-----2343443333333343364235534332332232332-1---1-13-111111111-1-11112-1121111-212122-------1-------------------------------1111---------------------111---11---------------------------1-113332222433--221------1----11-----1-------1--1--11--1-------11111-----1------------11111-------------------12--1-112111---1111111111111211------------111-11-111111-----1--------1111211-11111121211111112----1122122-1--4332---32412111111111--11113-5--1---1-----1111--1--111134-11--------------1----2-11111331232323332222223322221233233--11141------11111311111111111-321111111121111111111121111111111111111111121233122114222222222221121111112223152321111--21---21121111111112222222222321223422311111111114333222223342233454553331111111----------------------------------------1----1---1----2-- 442353H-H874668557556438BA9IKEGGEAIDCHEG9DECEB597465FD6768843535H554353434544324344555353FIA579J634A64876418QAB4A8757644355465685FQ4-65B336545B6525644473B5314523646443332D2545BJDG*HIFCLR9BC8GbHC7987R * d.144.1.9 RIO1-like kinases
[ 484] -------1-111111--------1---1----121---11111111111--1--------------22 1221411-----1-2----------3-------1111211-21122111221332123--2411112323-2222222---11-------1--1------1--11-1-2--------------121-11------11111----11-111-1--11--1---11-3--1-------------331----1--122222232122322211111122211111212222221-111111111111111111133231221111166112243422144333331123113333333333323223222322323331113333---211111111212----2222-1-11---1-11-1----1-211--1-2-2111------311113111-2--11111111111-1221231122--122-2212322311-1-11111111-1111111111331----------------------------------1-32--11-12222221222222322222222231112--331-----1-1-1--1--12-2---------------------1-11111-1-11-----11-122-1-1-----------------------112221--1--11-111----1111-1111-1--1----1--11132111212222222232-2222232222223222223544112212222222222222212222222231-311111111111------------------322212112-21--1111111----2-22222222-22221111111111111-2222-1111222221111111---1111---111111111111111--1------1-1121111111111-----------1--11-- 22--533-C53-343AA97534585962222222222222222221BA785658446111113212221142-214523411111---1843A23711115B622213C2MGLFJHFBB99DDBLHEMDe*F-JFO6DECEBCDD7DABACA5CDEAEJ546FNGABF79Q8FA2133--23198PXzy7eK42TMZa4 * f.19.1.1 Aquaporin-like
[ 485] ------21222222221211111----------------------11--1111--------222--11 2211432222221131111-12112211111222223233-22211142221343233113352332B6611111111----------11-1-1--1--1632252423------------------1-1----1-11-1-----111-111--111111111112111111-1111111-1-11--------------------------------------------------------------------111111111111111111111111111111111111111111111111111111111111--111---1------------------------------------------1-------1--42211111111-----------11111111111-11111111111-1111111111111112-1112121111--------11111-1-------------------------------122121111122222222222222122222222111111122211111111121111111-11111111111-1111-1-1----------111--1-1-331364-2--------------------1----11111212223313444433344443434434--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--141111122221111111111111111111122222211111111111111111111111111111-111-1111111111111113434433311111-1-221111-------------------------------------------------3 1111672-744-66454444444444444445433324442444444445446544454444575554455565755255544444333593436433335435663646RHHFKJIEDCCABCFDEICZ*J1JFRAD9BDAEJFBCDC9HGCKAFCBCBOYMPDOKfMYmGOFN3444P53264658B45C347CA83 * b.98.1.1 Leukotriene A4 hydrolase N-terminal domain
[ 486] 11121-11112112111--112-3122---3--11---1---112-11--111-1211221122--23 -11---11222--1-------1--15-----151113486-2-2----1---231-------1--12---122222325123211-1132241232----11-121-11---------------32332122312222331111131221122211111322112322-11111111111-1-1---453435224243332333333827663333263534555555631111111111111111-22--614-33-31-1224433311222222222222222233333333333122222222222233344-33313457D7778677B6B47GG69A7574125552244569123336425224-112--------1-311---2522311111111112--16--5-2421-45544238445442112-143233311212222223--1--12-----------------------------1-2212166144234433222233222333425125962-1232121112244461111--122-------1--111-864D457479777-43452-6B3----22111112----1------------1-----87B32-224143555546844454545584-----1-------A59736177797A9A87-7787898777798777778BEC78446A988899999989889666555571-544445444444--2------1111-2326334415--------233334333333133341522654323222---111-1-233354444456546-----------------5112222--------2-1------------------2------3234462546-12- --2232--22-5--1344333333633222222333322222222222344686221111111---1-1------11111------32235242421111212112-16131221231111111111228D1-33111111-11111112121111111111-41-2112A113--32281112-----4--2111121 * e.22.1.2 Iron-containing alcohol dehydrogenase
[ 487] 11-1--1211111112-------122211-11---1-------112111-111--1-12112221--- 2222222222222222222-22221222222121112222232222221222222222222221222222221222222112222222333423332--222222222222222221212222322222222222222222222234222232222222222222343222222222222223322233222233333333333333332333333322232222222222322222222222222232232222222222222222222222222222222222222222222222222222222222222222222222233334333333333343333333433232333223342343323333322122222222222222232222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222212222222222222222222122222222222322222222222222222222222222222222222222232222222222222222222222222122222222222222222333323222222222222222222222222222222222222222222222222222222222222-2222222222232222222221222222-22222222222222222222322222222222222222222222222222222222222222222112222222222222222222222222222222222222222222222223232222222222222222222223222222222222222222222222222222211111111111122332122-222222222222222222233333333332222 2222441-623333211211111111111111111111111111111111122221111111122111111112211-2112222311113111111111111333149697F66965444766BB7B5Kl7197G5764B558636564747C7656536B44433534614133434M3433553471553343336 * d.67.1.1 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
[ 488] 22----6686677777-3374---62233232-----------11-1---2-1--------3531-33 2283B22422221278833-37115A323333C99955DC3776544333325462422277935479894---------1-822122-----1------2131223-2---------------211525222343332211131744233322111111214413355112111111111154334---1233333332433433343333333332422223------232111111111111111111------------------------------------------------------------------------1111111111111-11----1-111--2--1122---1-1---------5124443-1--186A896352322311111111111111213422472-3223548335574A223273111131122222222-3322333121111111111111111111111111111236214553587888857666AA7B65663685A4874124547845437646544551432111111112222653111--1--------22313221-434485-11111111111111111111111-2122322335213131111122111111122123---2313------3211-212221211122-222221122221222222132322121111111111111111132112222--222222222221---3-----221253324---------------32223241324433534245355745343---------33223111112343343334333332222222-221111----------------------------------------------22-1 22--111-623-1163454644455463333332222222222333444434444354544411211111111111111111111122238343343334434445-3C3DAA6A921212-33743619J4-6451312222241121121122435645515533914622345744r7547493464536645748 * b.33.1.1 Rieske iron-sulfur protein (ISP)
[ 489] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 311197D-TD767598KH524434456334455754454545534394A7696967877546312111-11122111-11111111111QOAK**m1122G32B8D-BcG*GNJKIHFAD8CEDgP9eB**R1aJk8C9BHCDFB9EDA9G99NDQDEF9HE7IIt8NNMK9EF51*FZM443xM9B4E99A96CKIMz * g.85.1.1 MYND zinc finger
[ 490] ---211----------21------1225-4-195623343224-3-6424253-3331325---3-24 255-41----1----------------------111----132433523-141--111--22212113772--------154123331A789-7331--45552623132222222222222224332433355443365---115644556445554464537474354252133452435233214522364444422432332422155782223332-A244444454577888888888787975852241--1-2114622212161--512111-----112--1111111--------------111---111122246444546555736555432536-2232363313534122--22212452344312222-14222312343322222222222-2133241122213224332343332312312511113131111111121131523------------4344343443443----21123123335322222111111132222313444232222434722442222333543232431123231635645485434641352141755354534463431233312132223313-------4442111332322532445444433443345353364--13622------34334343334343433-3433533344344333333333334433433333333333333333333333243333333333322343333366662242554332332222322333443331112344436533534232333522222222465363333343144444333333333332253113344----------2-------------------------23512322134722 -------------11--------------------------------------------------------------------------------------------34331111211111211321114G1-12512221111111111111111111------1---------3-11Y1---17225-432221-24 * c.87.1.3 UDP-N-acetylglucosamine 2-epimerase
[ 491] 33236844333333342222222311111111---11111111-----2-1--95555554---12-- 112-111111111111111-11--111111111111111111113111111-111111--11111211111-------1111------1111-111---11111221111111111-111111111111111121--------1-21122211111111111112-22211111111111111112311-22111111111111111111111111122211111111112511111111111111111111122222221222222221222211112222222222222222222222222222222222222222222121111111111111122111111212112221111121111312222-11111222322222222232222222222222122222-2222242222222222222222223322223222222222222222222222222------------------------------222222222222222222222222222222333222222222222222222222222222222222222222222221121222222222211112211133334111-1-1-1111-1-----------11-11332111112224544444444444444444--11221------22221222222222222-2222222222222222222222221112222222222222222222221221-111111111111--12111111111111111111-11111-1111111111111112111111111111111111111-11-1122222222222233111111111111111-2---------------1------1---1--------1----------121-111-321 56556561K993448433333333434433444444333333334344333443443333334334332334333333333334334443433334443332355535N6H8A88CA79988A7F97D8g*G-DBF9788D78C68A895876F9998856B6A847655C257547A7a9775457AB3B94BA8992 * c.66.1.38 NOL1/NOP2/sun
[ 492] 11-1--1111111111--11111------1-----11111111-----------11-1111111--11 3362622322222233322-2322462222343333548824472353333285622222656254688723222222411111111111121111--1111312131322222222211111223122213223222221121124343343322111121133345322122121112112222222111133332122122222231221122111111113444331211111111111111111111-22112131124511211312332113431122111322223323231111111121111111111222321137111111131312111111112112121111111121112111112133222311111428673343444422222222225-45745835442132213445435627222222323412222222222554112421111111111---------------1111311211433336664544444433764444343373464232225425446537323334223222222223342242212-221113111123322232133531211211211111111111111112111144229232223223333333333333333333212432322222243433533334344433-3333344333343333335676432225444444444444444323233332233233333333322232222222224223322233222222222333333222225233333336322433533222222222233333333333433332222222222222231111122--------111----1-221222111111211111112111141212111 11--211-311112233335463555622222222222222222224344457634323332213111111223222-22111111222231323165542-23221142245222112-223233243EO3-43221124215-2232132241112211-11211411611312111J1111143463223241111 * c.36.1.10 TK-like PP module
[ 493] 11111111111111112111111221123122111111111111111111222111111111112111 3461511111111135444-45114544444456676495231234231211353111113341435355111111111121121211111111111--131325331311111111111111311111121111111221111111111111111222222111111112111322121122111111121111111111111111122111211111121111111114311111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111121111111111121111111211112111222122222122211111212322611111346456333343311111111113-22323322472127736696766A33121222333321111111111222121211111111111111111111111111111113342112112223222311113235342211133442111221253433232422123112112222222112342212111111112111222111211446433112122222222211111111121111211113212222222222122222222222221-11111-1111122221222222222222-222222222222222222122222221222222222222212211-1222211223322323222111121222111112122111222122221221111111111121222232454444444341111111112222222222122224334344222111111111111111111111111111111-111111111111112111111111111111514 22125551C55233645555445555455555555545555455554445444444545444333333-333333231333333333445745565645553644427G884545433344442892929U7-64A43244347334333422325434477857F5431E54442454X4446454455745246653 * b.40.4.6 DNA ligase/mRNA capping enzyme postcatalytic domain
[ 494] ------------------------2--1-3-------------------------------------- 1-1-*------------11-1---1-111111---------611--1-3---11---6--43--W-1CHE1-----11--1-------1-2---------4---D-1---------------------1--------------4--1----1------------------------------1------------------------1--11--------2----------2---------------------------------------------------------------------------------------------7-333---333-2---------2--------1-----------------11-----------1---------------------1-2-2-----------1--------1-------------------------------------------------------------1-------1----224444--11444432--1--------------1---1--------31----------1-----------------------1------28-----6-2222-2-2--------------22---B-------111---1111----1-----------------------------2------------------------------1311111111111111-------------------------------------A--111---3----4--------------6-----------1--3-2-------------11111-1--11-----------------------------------------------------------------------1-- 2356I3P-3---3121-22-1112132-------------------3459543311433212-----------1---------------8Q4-VBF545P-2-TQe5143vTYKOOTKINKJKIXRKUKq*P2UNWDLJJSJMRIFMKIEQHJWKNIMNHJHZaIr9PDHKDFE9-4A-------49CH24K62CGLY9 * b.42.2.1 Ricin B-like
[ 495] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3334CBD-G7534564555555554545555555554555345555455555555565555545554535565456636655555566636454455555444CAA2FR8HhWWiaPHJHEINKrpIgO**eBpQ*CJHIYGLYI9MIIFTHBjJMKJMBDMFAAF5FDBE89DB3667k76665JGGK5MB999999E * g.45.1.1 Pyk2-associated protein beta ARF-GAP domain
[ 496] 22323332333333333243332732332333221223333333323321111267666763336-44 235342-1111---21111-11111411111113232257254435222231334233--238143565461111111----333333222--111-111222222232111111111111112332223333332223311-34112111311--------21112213------------22233--2222222222222222222222222222222122211111132111111111111111211113----------------------111111111111111111111111111111111111111111-1111132--11111111111222-111-11--2--2247225-11341111---233211211111138463173354511111111112-556446444531322332443334351113332222537--------211-253311111111111111111111111111111212221195584222233233322473333222273B98122223424573344523331112312222222236322DD733741465531545252623335335A51-222222221-1-------33443112211312112222222222222222222221111223------53333435557577755-55556775555755646653343333343333243334444343334333421333333333333111111111221231332111111-111-11111111112111123333121112221111111111111112222222222222222222222221111114-221111------------------------------------2-112121112111 22--222-52132234543344434444444444443444444443324454443344444432222212112221111112222212246353332333234434-36244834232222222442227J3-3143222222342222222241422544723222524344333321H1113351484433322224 * c.2.1.8 CoA-binding domain
[ 497] ---2---1-------------------1----------------1-----12--------------9- 111-6--------1----------------------13---638------------------1-1-5-2--------------------1----------1-112---1--------------1---------2-----3---3---1---1----------2-112112--------------1--------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-1------------------2-----2-11--1-----111--11111111-1------1-1-21111112-1--111111-1111-11----------------------1-1---2-------------------------------------------1-1---------------1---1-------112--------1-4-----------------1-13-------1--------1----1--1132--1----------1---------1--2---1---1------1111111--11-1121-1----1-111-111-1-1--------------------------------1---121-------------------------------------------------------211----1--------------------211111-----------11-------------1------2-------------------1---------------1----------------------------1---1-11--31- 2-225BM-J7C7IFA64656AA3B898547B77488A5856648BB7A9E8CDGAC4AA685A79537246692543246366685757DI747ER3762A86A8925XKNQULSNKEBECFEGMMDQBg*D3QCW8CBIK9FDAAD9C9L9AM9GEC98JHFFBGHOCFPHMGC8GOA*9AEC9A9DG6FAB3BCCBN * b.69.11.1 Putative isomerase YbhE
[ 498] ---------------2--------1--31-----1---1----26--2--32--1--11-2-----L1 18V34---------23222-23--63222221532312641838331-1--21211-1--222-4424231--------------2--54D4-222---251-19582A-----------------4-31---2-16613--162524222111---1-------75563-1-----------1--21-1--------------------11----1------1------2-------------------------------------------------------------------------------------------4-1-2--------1-1-11-11---1---21----21-2--2----2--13-5-11------32611---12-22------------332211232-2--11---1211------1---11121--11111111---2-1-------22-----------------------1--11-11--3----1-----1-141111-121911--1---13-1--1-133---1----1----------3-2-54-6-----1-----4922238--3424AZ-9---------------------------------312--11-21131-2111-2-11----111-------------1-----------------------1-----1----1------------------------------------------------------1---1---1-------------1-------2122335-12112131--2--------------------12--5211211434-------12244A8---11----11-------------------------1-211-1-111L-4 2---1-4-2-12--46322-22-2322-----11111-----1-1-431133352121-21321121--1-11-1--1--1111---1112132311--1-111--11L**HGHIHC54679C9dJ6CBPyE3FBO955DD68G56BBA7F25N9NBFE9D6TaN86H77L89U5217483-343924C3932324146 * b.68.9.1 NHL repeat
[ 499] --------------------------------------1-11-11-------------1-11------ -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------1---------------22-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--FJ8-3111112AHDC58963548AA56464258535566778AIEHA8D6777899BB3221-2322321123-23233332133DCEHDNW3232733663-6Q9sohXaeRH9CGKKASQDaD**Z4bJhFF9ENHLLJBKCBGKFFRBLMNTAG9JJiK5BAL8KVQ7-8B6F454B7IgebAzL242A54B * g.44.1.4 IBR domain
[ 500] ------------------------------2------------------------------111---- 343-2---------11111-11111111111111111111111151-211111211111112112-122211111111----123444HGUG6ODH1--22222221211111111111111113332342353411111---21831122122221111111113214111111111111142111111311333333333344344221112334111111111111112-1111111111111111211111211211111111111211112321111111111111111111111-111111111111111111111211111111111111211111111-1111111111114211111112122132644333333536344443433633333333334-2252463443426557333444333334334335333346666666658645A431233333311113333133333333333333464345444443643544444469434434456567833865444653353533364644543334333333438454454574647862545A7554C4434455411-1111111111111111112111974551455335455555554555445444441-3534431233344444444444444244-44444444444444444444444444444444444444444444444444451444444444444--8445555333344443333333333333333333333333375555554565555545551111111113644444444445444444544444444433G-11----111111111117DF14--13112111112111111112111111112232 2-------1---------------------------------------------------------------------------------------------------1--------1------------------1-1------------------------1------2----1111-1111----1---1-2---- * a.55.1.1 Prokaryotic DNA-bending protein
[ 501] --1-1-111111221--222211--53-348242144--42132312424449-42224332344143 11---22722-236-3122-26--2112112123345211-665-3-22---4331----21513241325----1113147--121465861231---226632222----------------159488--7217556D12-A-46A444H1111------542179932-2---------1642-1---32121222611233123113312131543212181211311133334333333333113222322231224112333315121-24223312662354444433433445442432442421766434343341313332465151234431211113621533223-2523222-214-24354224-31-C226-55433412211111111112-43123522734233231117-111-81223221422222777777773-231311-------------235115---11------562212---1111--14----11--3-21-51A11-21-1451173A--656-A-1B2315-24512221471824215E2-15-2423-13238-2836331228432122145543394CEEFD9G64-1268-353A1-2-1-1641653-72342512722--19213-------1256-21331121242-31-1424-113211111127113255122111-213212211-21111-11--11112111-214--2------1112314115221113423351712-21221163121131-1-111-1-732-521213212112221116131216-1335433324323--3B112222432--1--3-3-F14--21-231-3533-314-341114-1----1-332 1222212-61-11211-1-1111212--11----1-21111111----221-11--122221-21121112111121122111122111111-111111211233311722----1-131--11-1-22391-11-121-111-1-121-121-22--221-131311113122111-18121--1---1-12332333 * c.66.1.45 N-6 DNA Methylase-like
[ 502] -----------------------2--------------2----2----------44444422-----2 2442222222222222222-22222222222222222422222242222222222224--2-72226222242222222222222222222222222--24224443-4--------------222222222242222-2---42222222422222222222222222222222222222242222222224AAAAAAC869AA98A422246A9822264222222226822222222222222222222254444444444444444442244442222222242222222222222222222222222422222222224426222222222226222222252222222244224223223382424-2-666622222224242222444222222222226-2222242424224664444445445222-423222242A222222222242244------------------------------24434624422D5555D7344455AC333314558444422224244227287742222222442222222222233266242226422222424222222442422242484244444424222222224422224422422422442222644222422464442-2----22-22264846424444444444-44446644444444444425558822264666666666666664444646222444444444444-2222222222222244444242422222222466666442422222222424224222222222222222-464422222224222222222---------222222222222222232--------------------------24422-4----2-2 --------------------------3---------------------24-626----------------2-----------------1-------------------6-------------------------------------------------4----4---------------------2226-22--3211- * c.78.2.1 Aspartate/glutamate racemase
[ 503] -------------------------------------------------------------------- 356------------------------------------------------------------------1--------------------------------------------------------------------45---2-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------4-------------2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-------------------------------------------1--111-111-112-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------1-- ---1886-1-----3----1111111111111111111111111111111111111111111211111-112111221221-11111-1-22-2222221132999-B55QTXSUQSPKINPSN*lKmM**l6fU*MOSGVLSUPHUKEFnHGjNQKNL7CN9F877L69M4782131x*tmj121577-63-g8n4Xe * b.1.18.1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
[ 504] 111-111111111111--------52224-22----------------------11111111111--- 2322221111122222222-2422422222224333226622222242122177542222225238A3222-------1--1B3--111111-111----211111111--------------11111111111122222---2422222222222222222222222222222222222222212211111111111111111111111111111111111111111111-11111111111111111111--------------------------111------------------------------------------11--1111111-1--111----1---11----22-1-11111111-1--2-2422222222262442222223233453453445-663676636O31DAA8A8BBADDE892229D75555HFO222222224222722211111111111111111111111111111B24521223324444445322244594444244653532112264222222222411224142222222222222221-2-1111111111-1111111-1222223---------------------------222212127222222222222222222222221-1222311111122222222332222222-321222222232222222222222223222222222222222222222222212222222222221112222222222222441111111111111111111113222425555555996755277722222222222222122222222222222222222222122-111111--------1-1-------------------------11111111112211 33--332-B32-3343334333233332222122222222222222222233333333222222312312222321222232122222233232243333122342-382I775677675445466484K*5187E6662765562544366386555647A37654549335852333O4333352363443431325 * d.250.1.1 Aminomethyltransferase folate-binding domain
[ 505] -------------------------11----------------------------------------- -1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 3122116-ZHE-579434323223234443434443344434433343553234133254342233332233232321223222235331343545111331277A13p1WSaXZZWKDPELQKxmGtJ**Y2oW*GEFAcEORTEKHKIREEjKKLPM6737BFK8YEEI4CE5-63Ga476F7Mbww3ZR3DCSIKC * g.41.11.1 Ran binding protein zinc finger-like
[ 506] 11212111111111111111-11221111111222333333331111511231D22222221-11111 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111311333313221111111111-11111111111111112211111121121111111111221122111111111112111111111111111111111111331111111111111111111121111111111121122222211-111111111111111111131111111111111111111111-111111111311311333131313333333333333311111111113111333333333313113333413331221111111123112211333112111111111211121111111111111111111-1111111111111111111111111111121111221111111111111121121111111111111111111111111111111111111111111111112122112222221211311111111111111121221112111111111111112211116261121112111111111123322221121111111111111111111111-2-111111111112121111112111111111111111211111-11111111111111111-11-111111111111111111111111111111111111111111111111111111111111111111111111111222212121111111111111111111111111211111111111111111111111111111112111112121111111111111111111311111111111111114----1-111111111111111111111111211212111 5366344-QAA6445676486766775652556556154535564555557566668675455366656563445461654555454554947544355454155844J79AD9B846676684CH6J4GbD-76B2655C658437324732B56576773A6565M46579776663*66644IDKK6F7HB66624 * f.17.1.1 F1F0 ATP synthase subunit C
[ 507] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111--5-31--------------------------------------------------------------------------------------------------M-*XsWvabQIOMOSHabGqX**x-*UlLIJEWFMaWAMIKLQHIlOeUOSLEFCvU41222K376T----S334----------5----5 * g.14.1.1 Kringle modules
[ 508] ------------------------22222222-----------1111111111--------------- 323-------------------------------------------------------------------------------12122144331322311332228352311111111111111122222221222222221113322222222222222222222322221222222222222212222122233333233333333333222233322233232222223322222222222222222222322222223332222222222212222222222222122222222222222222222222222222222224454443544624353443444443222222233322323222332222221111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111--111111-11111111111211111111111222111311112222222221222222222333332111-1--------1111111111-12-331111111111111111111111111111111-1211211-11111111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--11111111111211111111111111-111111111111111111111111-1111111111111111111111111111111111111111111111--1111111122222212212-------------------------33233222221112 3322667-D552655666746666556666666666866666677655665566667666664534642666444663676666664446A6676656666667662994C6846585575656673B3**8-86A6655645635575664577764548F46564344734867477e76569966C66J4656554 * a.113.1.1 DNA repair protein MutS, domain III
[ 509] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------1----------------1-----------------------------------------------------------1------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------- --33Pa3---1-A8Q8B988A98ACA989996976677674679979999A9BD89A4A899AAB6672A8597AAA8AB6AAAAA9779BBBDIFBBCB99Eikq2925DQSNTYEGCE9CJBfU6PEz*P3RNd8FC7KGIJM5GGE8HA7ODODIJ666LH9B8H6CB7I586GEAMB67R5FPKc8YB------- * g.39.1.1 Erythroid transcription factor GATA-1
[ 510] -------------------------------------------------------------------- --5A-61711-----------3----------8262---1--18------------------------1------------------1------------1-11-------------------3---7332-3-4----------21------------------4-------------------------1--------1--1---5-6--------------1------111112-1-2-1-121-------1-------------------1------------2-----------------------------------13------------B---------I------154-1-1---112-----5-AG---------16272---21-43123223332A-4-5--5-5-3--4442C-8541AD26-----12I62---555555551---13--------------------------------1-11-----2-236B-B------3211--17148-112--314611-4-3152---1-----3--------156-4-------3----4----31--151----1-2----------------------D---------3--2----8261-9----2---1--------1----------1---6465A123B--2-63811-35313--9---3-4-------212-2-11----1--S4YheeJ---32212-22-2----------------------------------------2--51-228----111-11126----------41--------L--1-3--7G5741-------2---------------------------1----------------2---------1-- ----111-----2212235712-32832222223333422244225875565B8675H5555222211121122211111148232-A62C22224---12734B8--2-T-6135LC6526E6JE9IDh*T3FJQ6A44L48F97A876P54N624L12--EFFEDD6144746-----1----4--2B-1-3**z*- * a.4.1.7 Centromere-binding
[ 511] 11121212222222211123355155562243--1222-----2-33671111-11121222211-24 112-335144535821211-13111511111132226857123334313332322214113429A443674233332221-142-122111212221---22112224122222222222222233242222234566663249265343323322322322423487432222223322226533311-12233333233232423256334324243382215555555534444444444444434454413133122223311332122413124446444422333333333333333333333333534111333313324555556545321222221342434-11444211121213211272422211233333423111344556633333333336-434333454332655444466554231114594366442222222221222116611111111--1111111111111111111-21111323222333323355533334444344121112--22234211433323--52212331111111--233225422222324332-2122111323333432621231111111-1-------4112233332212112212333332332232333343--223331-----D3463642445256722-3222645253365222222667785563333333333333333732644433-654554434444--3----------125332122412222232231122121112316666687846666366611111111135447333337664411------------1112331111-----1-12211112---------------------11111131111112 -1------------1----------------------------------------------------------------------------------------1-1--9------------------------------------------------------1------------331511-213--2-1-11-11-3 * c.92.2.2 TroA-like
[ 512] --------111111--333331--1--2--11------------------1--1-------------- 342--------------22-2-----21222-----------------------------------------------------1---11---------13-225-2-1-----------------1-1-1-11-11111-----5242322---------2--112333--------------------1--------------------------21--------------------------------------------------------------------------------------------------------1--1---------1-------------1------11---2-----------17336-----112222222222211-11111112-11211312121-22222222221121343111111111122222222-4552---1111111111--111111111111111-1-3224---------------------222222-1----------121212111211112222------------221-2-11----------223---21-----1-1----------------------------12-314112-------1---------------11--1---------2---------------------------------111--21---------------------------1----------------1---11111-2----------------------------72222111-2111121112--1-11-----------------14--------------1---1111--------4------------------1------------------3211 1311E2--31121-21-2411111-131121111111111111112F9-21122-126-1--D111111J2111-1312211131331B*eZ-32S323D2*128*-21-5B161232422452962936N615552312634h834132823h3A6266E2WDIqf2--165B117L1J233-1*A9I26-13**a*- * b.50.1.1 Retroviral protease (retropepsin)
[ 513] --------------------------------1-----1111121151-------------------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111112232553222222222233123334222222222222-----11122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222222222222222222112222122222222222222-21--1111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111--111111111111111-111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111311111-111111111111111111122222222221121 ----941-8462DG787C85999BAA8888888989777777778897786876779767773553332444555432334455756555EA7CDB75785B3666-268A6468595455455785D4Dl9295F45557557255572965D37555288555i8777C576F2741922276EHJI9HK3-44671 * a.149.1.1 RNase III catalytic domain-like
[ 514] --------1111111-12------2--1-7-------------------------------1------ 785-J1122221-112222-2111232222221111322132-87761684-654--3--344293459326333232---42-----AAA5-7111--4D13446225--------------12222222222235521---2-1111111121111111111121111-111---1-11-121--5522-1---------------222211--11-213321222231F1--------------1--1-1-1-11-11------22-1--111121111-11---------2-----------2-----144---444211126----------4----21-8121-2-3--11--1-2---11221--21-9773-----2223211112111111111-1111-221222211211511345344311118251121111111--------221-1112------------1111111111111----1151311111135545521333221133332332111121111231111111232112111221111111112112121111111-11111----2---11113114-11111----------------1---1111143-6714132222223211111123115--11111------23333222222222222-2222222222222222222233331112222222222222222222222221-233333313333--111111122221121411111111112122111111111111422222223222232545111122121121121111131122436868866633431-13111111222222222-3-------------------------22221443332612 ----11D------11FGGEMHJCOJNL4444446665655655444GDDHLPcYNHIDBA9A644-3--1--618---2--23223--1A9BG7C23673323536-1O-2---------------------------------------------1-132229M---------1---11---41BGESCG83-TQTT8 * c.1.8.7 NagZ-like
[ 515] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AA47ECA-P886CE9788878887848888888887687778888787888888788888888999995987998785678999998888B889G89888996A9829BBKMZIIQDFFCFEHFNOFQD**L1SMfBFFEKDGRACFDBDGACLGEAEIBBBDC788B8GMAACA699A*AAA89LJRM8IEAAABBDF * d.110.4.2 Clathrin coat assembly domain
[ 516] --------------------1--1----1--1------111111---3-----1------------1- 112-2--32221---11----1---------------1--223341--2---1131----221-4121431----1------3----------------11-111-1-1---------------1----------32266---42642133211--------22115533------------52512----2222222222222222223222222213243131111115212222221222222112222111---1-11111-------22-----------2------1-------------------1---------25214222222212125111211223-342-1111234-2211-112-11-122112-----1-2222112222111111111111-22222222111-11-11111111111-2-2432222212-------------11---------------------------------21------1----------11-1-------2-133---22-21--------2---------1111111---2--1--------------121-111-211115611--1-1-----------------1-1-------11---1----------------------2-----------------------------------------------------------------------------------------------------1111--4-----------------111111----1-11111121111121222---------1---1------1-----1-1---1--------422----111111111-------------------------------------11-1 1-55GD4-1---CB245442222322122-111-1-12222222224433564644611333235333152252223132255533---24152481123-725121-36*EFAAGLCCE9FBBOIBLAf*G-KEXADECIBBECBDFCAE98IBEBJJeXCONKPAZLb9Lf*81EY1----E-AQHM2MC1IWSTc1 * d.111.1.1 PR-1-like
[ 517] 11-1--1232223231-1-----1-11---2-1--------------1---1--114----1------ 36B-3-1---111123422-4511362-222255552766267D84524322634132--444355C6782-111-113---1-----2111--------3-123-32-1-------111111-----12-1-1-12211---2112111121111--------141121------------------11-1-11111121211111122----111---2211------321--------------1---11231111-12111--111---2-1111111111-11-------------------------11111111-1113-2222332-2-13111222321--22211331111171111113--5--3444-------31---1-1-------------1-1-3--2--32--122222322222213552342122--211111111-222--42------------------------------22F52123-33454431222233242222214132242-1222211-1111124-1--1--12-----------1-24-13-----1-------1--2--322331-2----------1----------1---113313--544535222254322225223234------1------21143221111111111-111111111111111111122222431222122222222221221111111--3---1----111---4-----444411112------1--------3333321-1-242222221112111123321---11-1-22242222233222-123133-----------222222--------1------1--------------------2112113111-2-- 2211552-O89-22275868776HBG8445555555333333355595CD8EHCA9457878121228223531265465322222123576556C2233224443-5H6FHJBCBB7EB6869G89C6Q*C-EAG6999988767877A8B77A877859F88957E57L466625A3L2225343498343344553 * c.1.9.1 Adenosine/AMP deaminase
[ 518] -----------------------FJ437279A--2--------TK16V2E727--------------1 446-1---112----21----211-2------23333163272241-------21-1----1--6258931----111--121162311134-2------1-1148774---------------221-1-3588387683F8973C47A44-3145------2712ACE2------------43-1-1-2-12111111111111131-433132112123112------541-------------------------------1--------1------------------------------------------------18254343243213121221---411--111315563191211323-1--413C661-2122-3A9B3349887A33433333334-989A84F8371166637798792271425-2-9678351--------133-4G79------------------------------1231-244235233565222244973323232554556-15668583365383-53A426393-------1-636D3ME438DA2TH88F1FDHC7BC6G67A6CD48412-----------------181731-533244623285432444345553433524---2875-------124-121111111111-1111111111111111111---12311-----------------1111111--2-1111--111----3------1231-624-----------2---1111112---3211213613345544231---------1111122222143242234344111------8-9A77AB------------------------------------12111-1----811 ----33--111---3--21-1223421-------1-----------1-13121222-211113--12---2211-231121---------11-141222-313--3-1-I3424514211-111223717F312341-2131323-211131-124224--2-----11----21-11----1-----12--463262- * d.110.3.5 N-terminal PAS domain of Pas kinase
[ 519] ------3222222222-25331134--24646-112211----34132144342------------42 223-332433324245755-56--74555554666644753553111-3---234222--336-4353354-----------22-4-2----1-------4-22333-2---------------111111121-1-22-----4-544444544664444444444646424242224242233222---22333333323333333343443433323222--------2311111111111111133332----------------------------------------------------------------------11-282222222526-3223453221---11-244733--12611-2--2-143333-----575553334224444444444444255655655352-5443454555445633234422224334444444422224422------------------------------24332222257457775888855778888767773553-333543333433343333235322-142222222333-1223222222222-424-44451224224123-------------------31-23225143333-32322222332222222332332--2421---2224433-433333333333-3314333333333233333464462234444444444444444433333332-3333333-333322-2---------333552222-2---------33333232333377775675557554545---------143342222234444--233332222222221-332222----------------------------------------------342- ------2-------333333333333322121222222222122223333333333333333223212222-22222222222222222343332322223-3522--9------------------------------------------------------1---------2-4544i44444C6CA3445533335 * d.58.36.1 Duplicated SiR/NiR-like domains 1 and 3
[ 520] 231242-1-------21---11-21222-2111233314333243254-1211433223331222122 3243631422321222222-21223222222212224232443331322451-2111111231152223221333111343222-11133111121-11111111-11211111111111111121111211211111122213131211212311111121111353112121211131115322433-3212222232212224532222112232223533344332251111111111111112--122-211112--12233231112112223333222222333222232221211212122222122333222123412222222232341112333525115433232233122323322121222122111111212242113322211111111111-22223324142-5455541343231112126233332223333333322222323-------------------------2-21-2222123222355543322224434333334325536622223321112332232222123222222222112433156533334333342334321443222214422211122222211111111111111112322243223242232233333342243261-3342212122234433334444444444-444444443444444444433355334233333333333433354444444323333333333331122111111411223212222222222122222222222222335655422235343223211111111111113222222322242422223312222124211112211111111211-----------1-------------111232-1222111 -----13-922122123215454374433-122111322222311134444244223635541-121212221-2221222121-121245233-21112254111-213222121321-2123241416H1-835321-231231213213213212212-2C6---1-2-11-2524742212356A1961212121 * c.37.1.2 Shikimate kinase (AroK)
[ 521] ---122-1------113--11111-11-121-311211----1243222211-22312131---1--- 297-74267772-222133-34--3-33333-11124216-44422-134211431----142-A5865522111B421-A11-----B655--211--1536165B2---------------111A75728K-1-22----33-C5-D68G--11------32-1574-------------1-1------1-2233362152533531-3312116-1252-14212425322-1--2111222-1---21212-111-13-3421232321--117-2-1-1-2-1211111211121133-1122112-311--2111--9155575464345115762-2-3122--481147722111--1253-131-2656216818415125247B34522221311124-74645884455-322422-53-36464312151211131222222224551-38C11122222122233222235212212221-1341-143137667982222-44443424148763465--112123418493691151-11-113111--9449124873244-25325113D584-A172222-343--2------1--------------1323334521641-1186243-1-132223113--47123------47572245556576786-556445692855766566348224GR65133323344233333A44833563-653635564433--643433334241-3373224312121293312112323-115444667736-4243-62132222222212344112115416332111113338575--41664521--------4-2--------------------------8---11111-4-1 --------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------1---1-------------1---------- * a.35.1.13 NE1354
[ 522] -----------------------17-122529--1-------19H-5U-ITMN--------------- 446-2------------------------------------2432-----------------1-31-32-1---------4-4-14--66A1-4--3---8-4189557---------------73324147AI264441--264GBIs7727421------7745URT3------------A1-------11111111212111111--11121122211121------15---------------------1------1--------11---------------------------------------------------281-C1111111518-8222-12111--1313-443112151---11---128B88513322439695312348822222222224-HGGIC3JI286234436546C64412121-1-131231---------311-2774---11--------------------------13---21--2---1-3111144731111-12-42451--33-63456-4673-33D218874-------12586G4MG517G54NF876-88B9566CI1-118I953--2----------------35-2---4233648466D3866759489968755687---2238------12-2-1-111111111---1111-1111-11111111-11--11-----------------1-1----1--2--------------444444334321636---------------112111----4644545786A45535545-----1---8112244444-11652312122112------B-FF2288----------1--------------------------12---2----B11 ----32--------434C83222243244345521222222213339855664656434565------------------------544--24-1-111--2-48A-----3211--1---1-----1-12-------------11---1-2-----11---12-------1221---------321-371-1-3---- * d.110.3.7 Hypoxia-inducible factor Hif2a, C-terminal domain
[ 523] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------D7547I2222662334222-999966225244A--561--1--71--1--------2-------------------------------------------------------------------------33------------------422-1--2---------------bM--4RcYhhhYefXXV-fVQhaOMfcZgTdVYYYYLRQO36GNraFRTTTVSYYYQSRTXYCFDMFPO--GGGGGGEDFGGG--------------2---------3---3----55525-6--2-2BCAB-43D-2243-444-------------------2----52--------5333------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------------------------------------------------2------------------------1-----4---- * b.2.3.2 Pilus subunits
[ 524] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---1-----21-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-------------------------------------------------------------------------------------------------------sYpZdfdMCKNLYLyYHaG**c-dWmIJHHUJMjUDOPRVWKEfOOMgPCF9I*m*I*8Fq**O--11-----2--------------- * g.8.1.1 Small Kunitz-type inhibitors & BPTI-like toxins
[ 525] -------------------------------------------11--1-1------------------ 2252722222222253333-342235333333355556B82733432221123632321174225489862222222222223324344323-2223--232225232222222222222222222222222222444343324244344442233333333333654563333344333343332233112133333333233333311111133322211222222221122222212222222222222212112111112211222221112221111111122111111111111111111111111211111111121133222222223212332222222321222222212211111112311332222422222233342222222222222222223-24224332232233332332222232222234323322222222222322222222222222222--11111111111113132-2223233324734345556666566888837634555322323323223222422222322322222222222233222222232232222111122131224246222112122222222222222222222223332332222322222232222222222331-22222------24233232333244443-3123223325343222223433336532433432333333332422222232-377777747776112222222222222333111121111111111333333322242666633435433434331111111112434333333344332232422445222222223333331111---133--------------------------22233322332222 33--111-611111111111111111111-11111111111111111111111111111111121111111111111-1111-111111121111111111111221171------------------------------------------------1----------------2584k22244CAAM1HA2442114 * a.174.1.1 Double Clp-N motif
[ 526] 22-1121111111111-1--2--1-11-----1--11------1-12-1112111-11111111---- 32222-11111-3--1111-11--211111112111-1111-1--------1-----------2---121-2222222112--221--222212-1---14121412-2---------------111111111111-------1-232522211332222331321325-121111121111111231-11--111111----111---1------1------1-1111--2--------------------3211121221411442132132122233333332221111111111133333333333331223332223-2-11-------2-2-2111343-1111-11-----1--11-1---1111--1111------22122--22--1-22222221223-43334533131-422321-143-1221-1111----1112222222244332--1-------------------------------23-21-1125555555544355645555248542313-1544212--21-12111-----222221222---1113232131211311111-1-11-22222242-11---------------------3323311-111112111111111111111111111--112--------311-2313333333333-3333333333333333333444-1--1333233333333332233323333--222221212222---1-----222211111111211-11-1---11111111----1-------2-1-1--1-1112111111-122111111111112213233223----1111221122--------1-1-------------------------1-----1----321 ----667-633-23524433333533333233333333233233333333443433333333323212-31-32323-12133333-2235343332222342222-6H9D9EAJDI9999AFCOL9HBg*E1GDP9AB8EAC9489885A76ID999859B9A6749485AB962567K54599C8CA48793DBCA6 * f.20.1.1 Clc chloride channel
[ 527] 22121122222222232222223122222122--2111111111112-21111-22222221221222 2243522322221243333-33223333333333334533233426422342322233225342234322311113222112122322112211112--111111111211111111111111132222222222222222223321111111122222221111122221211111221122211111121122222233133433342221123211122111111113211111111111111111111122133111123311221121222221221111122222223222222222222222212122111222111123333333313111111111211112211321322221111111111321633311111112213222222322222222222-23222222222132223224432222121122111111122222222-11212321111111111111111111111111111131122133313333333333333333333323333333322122132433323312223222222211121222423221122211322322343333445335334333333333333322222222232332112212222212211111311111111111111-1111311-11121112111111111111-1111111111111111111111112222222222221222222311111111111111111111111121111122222322211111111111111133333332223255452542322222222222222222222222222223234222222222211112111333332111111111-111111-111111111111111111112-11-----2311 2111324-522133224434444232444244433444344343232333333333335313532333-332222343233323344436564566444433374523A393744422244144572437E4-4484243624643322134253232443427443828822413222Q3224356584374443434 * d.13.1.1 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
[ 528] -------------------------------------------------------------------- -451722322222256655-5E44565555549699547713341-21---11121-1--3233336C77111111332132-112232211-2-----1512-62223--------------1111223111-422222---122133111--11343655-2213343-2-----2-----------13123343434434444442211234442221---------32--------------------14222232321442222223--1---111-1-1-------------------------------------24157443444454523332221-3311123121145323-21---1-12121411522222ADKGECABEEFED8899789898C-JMIKPGHHDJ12CDDAHGHGGHGEAC-11D4B9999666--------1----111------------------------------54411-----1-----------------------1111----12-11112111-1131222251111111342232C2211121121111166626372544-42C773111-1111111111111111-12D555531532---333333334544334443441-33432------65444536666666666-66666666666676666676664432376667676677575674656666511323233333333-11288887888881531111111-1111111122222222444133333333324234222---------2111433333333332212122111------31--------------------------------------------111111114181 ----1--------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------- * b.160.1.1 L,D-transpeptidase catalytic domain-like
[ 529] 11-1112378A8696424-----1A44A3384---------------------1-------3532--- 34P1811222211113311-1311291111114222448B1-115E412222689113111-4172G4924----3---21-8-----2221-11----1212213C14--------------11111111111122264---3912212222222112322111122211111111111114332222-122333332332333333215524333224351221111256211111111111111111112--121112------31---111111---------------------------------------------2112-----------1-------1-------132-1--112112-2-1-2-44334-----11A552131112133333333336-11721A23GF2-BBB1A56DECBA443411435176558---------22---11-------------------------------2632-654AC99AAC6333388C8544524B6C5A83-14431143384G3FC-21----------------311122-11-1--1----3112--1--11-1351-----1------1-11111111-1-1111151-21-61111111-1311111132112---1-1-------65BA1817667788877-5777A7878658777777A8A8DB111A79898BAA979A979653366651-333333333333-1--1111111111--821114121111111112222122-1-21333322652334315331----11---112211111222121145455344----------------------1---------------------------1221112111-112 ----111--------3333444375761111112331------111334446A944333222-11-------221--------------243312-33331-1112--3123111211111111-12324D1-32511123211--111111122--12121-42-1-112--1-1--21-111-3115323-11---4 * c.1.11.2 D-glucarate dehydratase-like
[ 530] 11-11123323333331121111111111112111111111112123121222111111111111-22 2234422322222324444-46224A444443A9993456476542222222432323112342424554222222222222411111223313-----1211223311--------------111111111111333332112421151121233111331221211221111111111113221121132111111-111111111221111111122311211111122111111111111111211111111221111111112211111111111111111111111111111111111111111111111111111131121111111112111111112141112213335372133422111-1211333122222135451114224133333333335-4524444339626665665666874611135455556571111111141113134222222222211111111111111111113122311111145545422222443533332345211311111233111124214111141342111111111112211221122222222-21211111211112221111111111111111111111111111221111212123433322322222223233---1123------13111112221211122-2222211222212222221222111111111111111111111422222222111111111111111-111111222211353111111111-1111122232221114188889887989884455111111111311121111112111223333344411111111111111------------------------------------22122121111121 1111331-311-22332333563848544333354443332333233325444555344444211111-11111111-1111111121148324383222232566-18336A32541241231222327J4-3232222312321212132222433624489215625356321643o11135C5AE37423222-5 * d.128.1.1 Glutamine synthetase catalytic domain
[ 531] 11------1111111---111---2111--11----------------------------1111---- 1212311111112131122-211122222221333325533333233322224463332233323273333-----------4-----111--1--2113334333323222222222222221---1----11-57733---33111111111111111111111111111111111111144444---224444444443443444474464444466344322222241222222222222222344422-1-22-1---111111111111111222222223322222-222222222222222222322222222211---2221212-2--222---------2--------------1121--23-2422222222224223222222255555533444-225225232422233232533354233234242222232222222222221222211122222211122222222222222222236931232233443343333322243333253333333233332222222444322211112322222222223222-2-2----------3231334--323333-21------------------------113223323343334333333333333333431-1432212111132222222222233322-222223322223222222324422222222222222222222222222222212222222222222224222233333223232222222222222224444424222324444333333333222222222222211223222223323333333332222222111-222221----------111111---2-1-----131-11-------------1323 ----333-322-3333332343323333333233333322232333233433433332233332222222222222222222222222233333434333443543-25362433353122223542417U3-43923-1333533232333451742338B2423-111A43334423e3213468B93754332223 * a.9.1.1 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
[ 532] ----1--------------1---1-11--------21-112111--17--331--------1------ 2-7-41------1-31222-22--2421222124441-53-243-3-1-1211-111---77--9-B679----------------1---11-------11-11422-1--------------1-111211232111135---112426223-13321-11123-721671112-1-1-11-1---------322222----122-111-----1-------1-------3-----------------------------------------------------------------------------------------------1------1----1------1-1------1--3-1----2-----1--13---4-----43435431233341111111111--34644557-21-2213131-1412111-1132212211---------1---1-63------------------------1-----1--1------122113155532213999A2B2-11332----13-2221142211112---11-----1-122-321234--1233311--42332112232229B-11--------1----------1------11--21111-11122212222222222222---5122------1-2--2--111-------1-----21--1-2-----1---1225------------------1-1------4--------------1111112222123-1----------------------211112212151-1-------2--1------22112------12111112122212--------1111------------------------------------------------33-- 1---9A2-112-1-3G9VFSCEJhadVDDBEEFDNNFIFIHHJAFBSDDQNVfkAANUDDCD1112------11-------11---1--CSE95CC22424729A9-4N2H6946853111111121229K5-24311113133--32-13--7422A4---6C21-211-11833953G567394ZHiGLM64-4-38 * c.66.1.12 Plant O-methyltransferase, C-terminal domain
[ 533] 1111111---------12111111111--11-111111111111111111111111111111111--- 33614---------24311-1211331111122324427113-2222-111-224---11-153413432-1111-111-1-2222221132-1------2-122-2-2---------------111132113122223311122-12-222--1111112221-11112-2-----21---11-2222-322224242332353335334423333122-31122222216--------------------2-1-12-1---33114511112----1211111-11222232222221111111111111111---111151-14111111111123--112-311--111111211112122111521-1133112-----31679-112-23-22222221223-11511415-64-7113326433674124145231345122222222263312122--------11--1-11-11111-111-11-1251-222245677753333255774444249275475-3553212--3-6368112-224---------11-131-111-111111111-1111111111111231111111-1---1111111111211-2222132112-33-----1-1-1111----1-2----1-2------63441336446666566-46465666564765555559A74521-6466666666656565445444554-355555546666-------------2222622221311312333211-11-3---42333336651363-1343-11111111-1--1111111111211313111121111--11331111--------2--------1--11--111--1111---1121122222-61- ----221-21--1116767533465444465453233333333333533338D512512222232123121141221111233343224--272211121422222-182B7775874441445B94B4QhD-C7954547435354444544B5444624133232739668541-11-1111211147151311115 * c.74.1.1 AraD-like aldolase/epimerase
[ 534] 331-11-1-----------1---31222-111111112112121121111221111111111------ 23323---------21111-11--2211111212221311-454-11-11113221-1--431-313434----------1-1-----1111-1------2-123113---------------------------12222---1-1-1-111--1111121211-3111-121111121111-----------11111-1----1-1--2332---1-1-1---222321-----------------11-1-1-3--------11----------1-1-------------------------------------------------3333333-3-2---1111121--1---------------------3-----2-------11111-11111-2-22-11-1----1--1---31-2---1121111211-22-1-----11111111111111111--------------------------------1----11---111111-------112222-2113-1-2------11-------2--1-1-1---------------14111--11-11111-1-1111-1--1-421----------------------------22-11-111111111111311111131114---1-----------112132222222222-222222222222222222211122233----------------22123332--122222222222---1-1-1-11111-3211111-111111111-2222211---------3----11111-1-223112212-42232333342243---------------11-------------------------1---------------------------1-1- -1-18A3-733-22558866677C9DE66666676766765666667667B9AB66565666333-221322333222222334341--49585744335525454-7C5qDHAAEJCABCCACIIFKCm*C2JDHAA9BFB9D7B89B9ACAGC9BAA9IPBGFEFIDIT8FE83443X33377AGBI6AE3494764 * c.67.1.6 Pyridoxal-dependent decarboxylase
[ 535] 22424222222222222222222222222222222222222221222222222222222222224-22 2422222233322222222-2222222222224222222222222222222222222211326222332222222222227432222222222211-111212222222---------------22222222222222222222222222222222333223222222222222222222222222222122222222332322333222332233222222232333222213333333343333444322412111121112222113132214333331222232222222222222222222222222222222222222124333333333322222222212422323222222221232222212223322222113222332222222222222222223-22222222323232222323333322122322222222222222222222222222212222211---------------11112222223333243333333333334444443433522222222222322222242222222233222222222222212222232322222222222222222222322222222222211211111112222222433222232222222222622222222222113322321122234223324334443433-33433343433333333332222222233333233333333333222222321222224222222111311111222222323111111111-21--122222222222233333333333334233211111111222252222222422222222222222222223222222111111112---------12-1------121-----22333222222222 11--112-311111222212222212222222222222221223222222222222222222223222222122222-2222222222222222222222321364-23151342432223323432225A2-3221223212211231323222131312314211111611312222H2222242242222232222 * c.78.1.1 Aspartate/ornithine carbamoyltransferase
[ 536] -------------------------------------------------------------------- 2244822222222234433-362233333333455574655334411133332421111144B2865DED611111112112A444441111111111111112211242222222222222211-1111111115555611155S8A7776568866678866579AB758555558555532-1122234544444445344445455555544445555332222227522222222222222222222111211211111111111111111111111111111111111111111111111111111111111111155544444444444456444333555224534444544445444455212435111111111111111121111111111111111-111121111111111111111111111111122222111111111111111112111111111111111-1111111111111111222222122555575344545544444535556454411333342222114324334222431111111223233322142222232221334433334221224331222122222222222222222211333423433333244333434333433444431-1533311111142333333333333333-34334232333342332232223333323333333333333333313213322343444343443112122222333311333111111111111111111111111133333333334333333331111111112444533333543332222222223111111242222222222222242111111-111111111111111111121311222222511 11-----11-----------------------------------------------------------------------------------------------1---2-------------------------------------------------1----------------4112K12222668A-63751---6 * a.4.13.1 Sigma3 domain
[ 537] 2211121--------12244343152426212213111-1-1----1-1-122--1-11--2223--2 -122B54555451465466-66337766666767779AAC1E6F47334551546553--8452977C9954655444--1322-2222234-4111--27252C2934----------1111432311211232555571116274533341122--1--114335343--------1---53711--1124778675B939A868A1122-3BA92-164453454347C12221121222221-411112214434124433113313131211-111122122211111211111------------14443334442-335344433333422111167562112534--22--2-2-11212--122145332-----323333223412211121111113-55556643343-755445444543231321121-2115433333333111-1123-----------11111-1------------12---222222665433222245342222224362422113331242245315213212--312212112121231332312211211111262231321222275121---------------------211--771211--215-12111-2111322223-----21-1------114112-1111111111-1111112111111111111112112-311--1----11-----111111111-2----------------1---12-1217131211-1---------33343332231144343436344432345222222232-2113323325423422--1--111------12121223--------1-2-------------------------13111121112223 ---1423-3221-112422211144441---1----1-1-------3223313133241222-111--------2----------1--121-4411--2212223313E76-11-311-21-6-55-22392-13125---21-11--11-1-1212111--161-2111212134744C31244433B3323743127 * d.113.1.6 BT0354 N-terminal domain-like
[ 538] 44----4444444444-44644424224-222-----------------------------6644--- 2484522222222222222-22222222222222222244222222-22---222224--22422222242--------2A4------22222244---22222222-2---------------2222222224222244---24-------22-----------2----------------22222--22422222212222222222222222222262222------42----------------------2-------------------------------------------------------------------2A64888888886862844844428-2-2-24-IE68D6-282--22-5-24-222222222645443325455522222222222244444A442422622466866A466622222222222224444444444424644-----------------------------2242226632444466544444447E4444248AC242422244C2444462426222-224222222222---2822A844----2-----E8E2I3B--22622228-------------------------2222-2224242-2222222622224264242-----2-------4-2-2--6665666664-5666666666566666662-------26452666664626226-3426554-----------------2222222222-2248---------------22222222228244444444444442446-------------2-----22-2222222222222222--22222222----------2-------------------------222222422222-2 ----222-422-22212221222222222222222222222222222222222212212222222222-12222222222222222-2223222222222222224-25252322331211222222534D3-2343221222221323321-3123222322322242262242222-----2322451222242222 * c.26.2.3 ETFP subunits
[ 539] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------HbYQ*VfbLMQZXc**Q*T**t9*g*JTSQfUf*lGfQMI*GK*RpPZe9O*-7999---p--6------------------------- * g.23.1.1 TB module/8-cys domain
[ 540] 5512-364677766651122321A2334132211111111111343343-22312221112321---1 -684A11112221145544-44--44444442333376D9164412-2-11-532423--122145A4561-------1-3273-111------------2-123-32------------------------1--34422---522222321--222333222223323312321112122162644-1-235557586592767676244433878244653511111174---1-11-11---111--1-------------------------------111----------------------1----1--111-----1-423333443231-4333---341--31-11432-32215-----1-12225335------37762124334322222222222-44644445334-111124145351344437253434425--------122-1-11------------------------------2345-222232224221333322433233332237895138957632154526322541212---1-111111464-536--1-1------1311532-144343632211-121111111111111121112--22-3116232-31111332233212112531-11124------12-3-111113122211-111112211112111111222332111121112111111111221-----1-1111111111111---2------11113412---------------11111-1112--33342242423222111---------6112144444121443313-32---1111-122222333--------1------2--------111---------1111133222-522 11---21-63223336444666654743332222322223122222534855C754335323334111-31131411-1115453411122342232322142313134174635395533455972537E415453451433643545143373564534329243221545641542F4434425655553121112 * d.157.1.1 Zn metallo-beta-lactamase
[ 541] ------------------------1------------------------------------------- ----121-111-2--------2---1------21111------1--2--4432222-1--1-281-111---------6--1-------------------------------------------------------------2-------------------------------------------1--33866666588786766AM9CAE86864662A37OSSURO521AAA9A99AAAAAAA64454H11-EN--4-4FD--NT2443472766B7AA9A99BHFFFEFICEDD9999B99999999688---988D-5-6P4444444846-Z--1344-1-32313--------1--1BB9-315-----------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------1-------1----------------1--------------------------------------------------------65B-------5--------------------------11-111B745284AAADACAA9A-9B9AA99ACBADBAAAAABFFH99232D8AB9BBCBABCDCBB799799873-745555555545--1-------------2-44463411111123311111-1---1-----1112111111111----------99996666658589--1----111-------4------33313211---------1-33221333-34332--------1-------- -------------2-----------------------------------------------------------------------------------------------------------------------------------------------------1------2--------------1------------- * c.44.2.1 PTS system, Lactose/Cellobiose specific IIB subunit
[ 542] -----------------------------------------------------1-------------- -------------------------------------------------------------------11------------------------------------------------------------------------------1--------------1-------------------------------------------------------------------------------------11---------------------1----------------------------------------------------1-------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------2-----------------1------------------------------- 6433DA7-O884889567756766665667866665675666666667877676787777779777776788778888887999876767B768886666586E9928ECIRWNKTLHECAIHFZTFVGy*N-WLgEHDEKHHNJEJDACJDCMFLHKHAC9DCAB5DBFGAABB7868*76686QIJb6TI55EBDB6 * a.47.2.1 t-snare proteins
[ 543] 111111211111111123111111--------112222-----1112211111111121112111--- 44423---111----2111-1---2511111-11111154222-282--421625--6--43-146845521---1--3---3111111131-111----211142213--------------11112111111222233-11131212222-1111111111211111111212112-11-321--223-15222232222323222954474232313552157755643266666666677666644578331441-4-555--46215--234411121111--211222111211111111111111134---33372315G77777774731B11142332-3-2121-----------3261312211-11------1-3241112-1214444444344A-111112134A1-A4445546566841-1-24622331531111111133311222-----------------------------1--11233334999998799986589999968AAB685311444414226367782211323311111111-11111-21--111122111311111112111-1-1111111-2221211111111112111-22324321214251111111111111111111--1111-1--11187456864557477744-5544679445575444444BAA664664533333355435334945444443-755555555565113122222111141554333343223224443---1------514444563453333245522222222214336555555445711--------------22112222----------1----3-1-324--222-4--11----321--6---441- ----114---------1--11111112------312-1-1-11-------11211-------------------------------------1-------1----1-2-152222-3-2113222-1234C2-221-2212-11------21141-1-1163-12--------3----1------31-5-11--1---- * c.80.1.3 mono-SIS domain
[ 544] 11-1--1111111111-122222143333333111111111111111111111111--1--111--11 1112433333343354445-4333444444443333445525253232343333333322333344645441111211-11-32222233331311-111333323332--------------233333333333222221113253533332233333333333245423333333333332222221-334444444443444444224434444233443333333322233333233333333332331----------21-------12-33311111112112222222222211111111111112--222----22-12----------111111111-1-121112443111--222112-112222222-----222112221121133233333332-22222222222-2222222222222222211322222222222222212212123-----------------------------2222222222223333342222222233332342222222222222222122233223222242222222211122313223122222222-122222222222245222122-22222122222222222222224432232222333333333333333333331-12232-1---164443424455455544-4444445455455444444445545534444444444444444444433342-4555554454542212221122222223333332332333332333334323222326766332422222233222222222223435444444334433222222223222222-222222--------------------------------------1--1-1112333 11----1-1---2222222233345352222222223344434222322223233322233322222212222222212222222222223222222222232222-14-------------------------------------------------3--------------1-3233M3335254682731352222 * d.161.1.1 ADC synthase
[ 545] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111*qd-735-23434443344444444344444434343344443444444432445444434223132232332-2233234333327441552444312341-UABtJVPTRWNOLHMNLTRJzLx*R1UQ*KONNRMLNS6NOJ5NKKyLNLNMHx*ESK43F8EK54RY1223A2213332554231145666 * b.64.1.1 Mannose 6-phosphate receptor domain
[ 546] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1-------------------------------------------------------------------1-----------------------------------Fust**sccUdbWf*nXwd**eEod*FXYUceaYSJaXdXcWN*dbUXT6E5H9978J88O5724------------------------ * b.69.12.1 Sema domain
[ 547] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------386--pcaZYboU*pd*e***5***ceXR*el*cNgaKSwRV*L-1Ig---412-----------------------------1---- * a.28.3.2 SCAN domain
[ 548] ------------------------22221131------------1-2---211----1----11---3 17F2M1-578611-RFEBB-BL11JHBBBBBEOYZYPKig1D5B5IA92551FFJ24A--J8B1H7KEEA1-----------4-----1112-1322111B196HFD1H---------------111-11---123331111-31612411111-----------3222----1-----1--1-2-----1-1334344541444334143311445---54-31111119C-22222222222221222251----------11--------------------111-----------------1--11---11---111----3211111-1----------------5-----1---------------E-2D239-----25D65114211-1----------5-11421411BG6-9651BA8DCBCA12563-C622221-2----------------------------------1-----------2467-13223555765-222166664444-3A315645--227411113-616112222-22--------1-31139112-112-1111--1-1---3--65A79D-2-------------------------334313231-11-2111111-111-1-11--1---3-2-------1----111111111111-1-11111111111111111222-----1-111111111111113111---------------------3---------112-1---------------4444412-1-1122321313-11111--------------111-----22-2244333332121111---1CC88DD--------1-2-------------------------1--111111113-5 1--1111-311-2331331122212121111111211111111111322214331112111141311212112221111112212211126332211111111213-2514311143-112222312227D2-22321221223221222311222212---121113131111123228111232126221-12---1 * d.129.3.5 AHSA1 domain
[ 549] 223-1-788888988A--21111-2---1--------------------------------1------ 15C24---------1--11-12--5711111433331369331411---11-2121----1-C-54C655--------1---42--2-------------1-3A8-8----------------------------35533----A-1-111---------------1-2--------------23-------1-----1---------12---1----21-----------1--------------------1----------------------------------------------------------------------64-24444344434-5------31-21-112-312342-3-4-------8--7553-----46OQR514696D71211-11-111-DCKBCJFI9A4-722411A5418FC745-BA1555588977777777B5532721------------------------------4672-79748FKKKKF33331KKHH333313E8KIEL5-488875711E292G2242-2222-----------2321-3-4111121111--1115211322-266-5-------------------------222--6223-7-223333352222222--2-2----1---------1--2--3332322232-3333212323323332331------------------------81--1112-----------------------------521---------------1112111-2171999943D6686774423---------2---4----------1123233----------2--------------11---------------------------2322-----15-- ----111-----11-21222121121222233211111111112221311122211111111-----------1-----------------11-------1-1----277F23234D22352635D5544B2-32452235236232324E43A2624626O2A83C69D8M384-23-A---3459D82A61131112 * d.133.1.1 Molybdenum cofactor-binding domain
[ 550] 222222211112112-2222222222222222222222222222222222322222222222221-22 2222222222222222222-22222222222222222222222222122222222222112222222222222222222222222222222222222--22222222221111111122222222222222222222222---2223222222222222222222222222222222222222222222-22222222222222222222222222222222222222222222222222222222122222221222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222122222222222222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222231112122222212111111121222222222222222222222222222222222222-2222222222222222222222222222-2222222222222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222------2222222222222222-222222222222222222222222222221222 2212222-622222222222222222222222222222122222222222232222222222322222222-1222222222222212222222222222122122222422421221222122531322B2-243211-222222221222132222124422222222622224444r44444467C2664432224 * a.24.13.1 Domain of the SRP/SRP receptor G-proteins
[ 551] 44533533333333333333333544442444444556555555555557566755555554443333 -1-1212122222122222-22222222222222222222222222212111222222--222222222222111111--11121222111111----------1-111---------------11111111111222222222-22212212222111122111222221111111111111112211-11111111111-11111111221211111111--------11----------------------------------------------111----11122222111222-------------111111111--------------------1-----------121121221-11222---1-21111111111212222222222222222222222-11111221221-2222222222222211211111111112222222211111111-----------1-----------------12111111111222222222222222222222222222211222221111211112222222221222222222222-1111111111111-11111111122222111--1----------------------332221222222222222222222221222221-1222211111122222222222222222-22222222222222222222222222222222222222222222222222221222222222222--1111111222222222222222122222222222222222222222222222122222221--------222222222222222222222222222221121-------------------------------------------221121222-1-- 43555542E54355545535555345455463555445454555554444545444455444555555146555566466555555444585555544445446473497A774445255644396584CR4-B57244462355355435329445456AA54553944544545645q6655555886555554432 * b.122.1.1 PUA domain
[ 552] ------1111111111-1-------11--1--------------111-1-122-1------11----- 359251----1--154354-441156555555855528662748331--432657333--346-54846431---111---3212---11-1-------12--141211----------11111---------1-122111112-1343441--223-112221146452-1--1-11----2-1-----21-11111112-122212--2211111---11--------221--1-11-11---11----2-------1---11---1---111-----------22---------------------------11------1-31------2----2------1----1--------------------13-68775-----266AA1-244531----------2111311411155-43324435432241322--2-----2-2222222234411332----------12111111111111------34832144255779753333355565455447578ED5-245471222444351533311221-------1132562221-2---11111-1-1-1111-42236912---------------------11--23--2-22122111322221233332322222---11-2------2111-211222122221-21122222222223212222221111-222212222222222211212122--111111111111---122222444514333---------------333322322133455443331425365451----11------1-----223223346465233----1-2-22111---------------------------------------1-112---31-2 --11311-21--226787787558C772243334443433333322865C9CBB6789654533222211313-3222222333231126D48E8A4655132131-2I3BB776F84367656DE485DZ6-6484433665743422263367876F469-64--3---C94119439122236FK76563142452 * c.69.1.9 Dienelactone hydrolase
[ 553] 1121112-11111112--11112431122331111-11111111111111111111131231--1-11 3352621111112111111-111111111111211114114112412313453522341143416125562-111122112211111133341322111111112221111111111111111211111211114111111112153323331122333322222322233333333333334231111111456768767566679632443566722326113333335322222222222222223332422111112223311112111231112323222222111111112113333233223333244222444214324222222232323332665514134241156111112111111112313722211111114353252412211111111113-11111121434132262123222127212115211111111111111176211111111111111111111111111111111115544111113112313411113322111121132121411233122643311211121211211211111121413341221111221111122311213222213231111111112111111111111112331111143122113332212422222251121-1111211111111111111111111211-1111111111111-1111111111112111111111112111111111111111111111112111121222221113111131111121111-111111111111112123321112111111111111111111111121112111111321111111121121114333333333333333221111-----1-1-111----11---11111111111311 2111112-522-33323333343-3323333333331444444333122331323323213233333333333323323333333333338331243223343331-2E38231142443133352143993-336413321332333233333453332-124332333133536445X4444476AG3985544435 * b.87.1.2 Type 1 signal peptidase
[ 554] ---------------1--1-11----------------31222------1--1-1121112------- 3452F11-22111173422-23--282222234323HBA92ABI954-2123774234--MH31N9JGQGD111-21113744----13332-2------1--1123-4---------------11-21214311333222314321111221134-----1--121241-1-----1--2-33311---A25554445745457565266765377132642222233395211111111123111111137212352242235113413313-5312-12121411221222222233211232133212134111222243216534765625-47B73-111113-3564389684215172122-1-1-17228-11-24567A5232322123323243436-66648938562-9235868874B88521123523326572222222213112343--------1-----11--------------115112322859AAA587776547897884699A3453--327221213493M5-43-1223322-----11-31-2332-241-22--1344363343322129513----------------------1--112133114-1-21344523174522725322-----12------2522-422551222322-632221322351323233144432--32352444444436324411322121-2--------1------11-112323-1436-11---3211-233-2222222--1115586754528C731421----------5431685881322321-1213---2111--6-111111-------131-----------------1---------1----1-1-13-1 --------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------2--------------1------------- * a.35.1.8 Probable transcriptional regulator VC1968, N-terminal domain
[ 555] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------21--11--------------3---2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----63D-----33724555555555554455555255453555355555767H5555555554544424433445535544553444447447595445243CCD-K-8PbgWbZfNLMIKMNsbGjK**a4tW*FNIHVKPSEHPOJHWHJlNUQNMCIKBCE9496768DCB11-15332-1-244521327CA9- * a.4.5.31 DEP domain
[ 556] -------------------------------------------------------------------- 2222222222222222222-222222222222222222222222222222222222222223222222222222222222222222223332221222223222322221222222222112231122222222222222222322222222112222222222232222222222222222221222222221222222222222222222222222222223222222222222222221222222222212222222222222222222222222122222222222222222222222222222222222222222222223222222222222222222222222222222222222222222222223222222222222233222222222222222212212222222222222222222232222222222222222222222222222122222224322222213222222222222212222222222222222222212222222222222232222222222322222321122222222122222222222222223322222222222234344443433334332222222222222222222222222221222223222222222222222222122223122222212222222222122333323323-22233333332332323332223322332332232222333331323231222222222212222222212122333322211222222221222222222222222222232333212122221222222222222122212222222221222222222222222223333222222222212222221-111-11111111111111122222222322332 43--221-511-1122221122222112222212122212221223122221222121121222222222212221111122222222123222221222112112-1724533355433245432241EK3-437322333333233323234433332111121-134311225274M33323456929D4342323 * e.38.1.1 Release factor
[ 557] ---1--1--------1111--1122--322222422222322223223223333------------22 2223333233332433333-3333333333333333344432323321333333323211333233333332333222-223122333222222---11-42222-332---------------222222222223313322322432333344333333333423333433333333333322-2234133433444223333333323443433444322--33333325-2221122222221221111---1--11---11--11-1-121222-------22222222222122-------------233222333134-4311111113132-331---213--324537556633-632222--2-342222-1111322222232222233333333332-22322322323-2442222222222322133333333432222222223342222-----------------------------22323233334333333222222232222222233222222222223333333332232432222222222333334-2322256225667-2222232243343-34942222222222-2-------44223332332523-2343333333333333333333---223322222243443434444443444-4424444444444444444444443324444444444444444444444441-44344444444411-----------2252333331313333311333333332223222222223222223222222222222233323333333333111111111111112332333333--------------------------------------4--2-222333- --------------2221222222222222222222122222222222222222222222-2222222222222222222222222-22242222222221-2424-------------------------------------------------------------------1-2334c44433343A2F4--3333- * d.58.18.6 IlvH-like
[ 558] -------------------------------------------------------------------- ----42-----2-245533-35225433333557675775-22322232222222223--225-2464493-----------------11--1-11----2--2---2------------------------------11---1--------------------------------------222------11111111111111111------111-111-1-------1----------------------------------------------------------------------------------------------------------------------------1--1-3-----------1--3223-----213332212323333333333333-112112113431233322322233243222122122223--------3----232-----------------------------12121-1342345555631333334522222465547551-44422333433454332----31----------3311A73-----1---------2----112182-1------------------------------462324--1222214222223222222----11-------1------1111111111-111111111111111111------22-----------------1111--11--1--------------1-----1111-4323---------------44444343446-88884668776875344------------------------2211111111--------111111-------------------------------------------------- ----JH4-422-22945675446955D981233333977777777722123348------11D66222242262422222266686---4C45433222274CHBH-A4EaC948787398998ME9E7S*C-CEA78A9C588848664A52A97769EHF6M97II884DMAO2792G22279A4AF4B622LHKH3 * a.29.3.2 acyl-CoA oxidase C-terminal domains
[ 559] 111222111111111111111111211111112221111111111111111112333232332221-1 1131111111111111111-11111111111111111111111111111111111111111111111111111111111122222222222212221--233323322311111111111111222222222232111111111221111111122111111111111211111111111113323322133444444445444444534444444433344433333332233333333333333333333333333333333333333333333333333333333333333333332333333333333333333333323322444333424222222222222342232122121122222332222113211111111112221111111122222222222-22122121221122222222222221222222222222211111111222121221111111111111122111111111111122112123322222222222222222222222222222211222222223222222222522332222222222222222222332233332211111111222223222222222222222222222222222224322222222222222222222222222221-2222211-11122222223332333233-33333333333333333322222233322222222222222223323222321222222222222111211111333322222222222222222222333333222222333322223222222222221222222333433333332332222222222222211232222221111111111111112-212122111122222222222222222221113 1111432-732133311111111111111-11111111-1-111111111111111111111211222221122211-1122221211111111-11111111222128326333332222322392226E2-33322223222-2221222262221222523222223211323765O6654463451345555655 * b.40.4.4 Myf domain
[ 560] --1-1--1111111112321111-------------------------------252-2-3211---- -13-3----121211------1---1------1---12111--421--242-243-----23213-3357221111--1---1-----------------1---111-1--------------------------12222---211--2----------------2--3-------------2211122-115-----2-11--1---4466741-1-33-2179AAB9A-1-2222222222222211113781-562-717BB--892-5634689223833454488676675736444444444444445566-544C1--7B222321311119---1121-22-111--------3---1321--3-1-3113-------322---1-111----------1---1-----1---111211112121-----11-111111--------------2---------------------------------2-1------111--1-------11--------1---------1-------2------1--1----------1-------1----------1-1--------1-26-----------------------------1161-21---11111111--------1--1-------------36751813223344444-23343234342422333348A89A12-2122222222222222522112331-611111111111-------------1-1-1---1-------------------------1-----1----1111----------11211111121211--11111----------1--------------1------9-----2------12------2222112-1112-1 -1-------------422435543333111111-------------5322365643211111----------1----------------242223--1-1--------F1dBFEMDIBBDCBCBBABEBGdA-9ADA88BF8BA8BBCABAA9NDCAAG56j-5I6V16BE222--23--11128FZov3tR11HLHK1 * c.1.8.4 Family 1 of glycosyl hydrolase
[ 561] ------------------------------------------------1------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ ----BB2-1--188B53455555765634232322123333233444334314234211232353335413433342233344455757593346445446-7YUS1C29*ivfleMHEDCJIJkVERHs*R2WMfCGHJQFLSLDMHJ9KBAVKDIGJHGDGcZdIhSjacsBv-2-15--12-1-3534121A4BC3 * b.1.18.11 Arrestin/Vps26-like
[ 562] ------1111111111--------11111111-----------1--12-2222--------1----11 4221322222222234433-34--3533333344444344221224222111353111--2242113242122222222133------2211-111---1512243433--------------2---111111-2----1111-14--------11111111-2---1--1111111111111-------3-32323313113121212222252312-2222232222222222222222222222222226112222121122112321223121121111112111111111111211112111111112113322112121111111111-1-211111113112231311321-12221111111112-25222-----323444222232222222221224-36234333442-3553442534362322232222222221111111134221311-----------------------------12232-222123243223122233422222222422222-122224422243331222111521111111114232221321222122222-2121121232232223211-11-----1---------1-11133311352323212347323344223223222----241------23112322222222322-22252222232222222225321111222121312314433232-122221--211111111211---21-111433312232111111-----11113235211-111-224224232224343561-1111-1-1212211131422323223422232------2-11--11--------1-3----1-111111111111111111111-1-1-1112212 11-1115-E7D21143554444444344432334444454244333354443444444444422222212212222212222222133335353333333-44332-4I2744546D5456544AB6A6De5-68934644665444535465B4635531435553433D34833683M4445533754464333334 * e.8.1.7 Lesion bypass DNA polymerase (Y-family), catalytic domain
[ 563] ------------------------1------------------------------------------- ----1211222-2--------2---1------21111111---1--3-15543332-3--1-271-1121--------4--1-------------------------2-2222222222222221211---1---111-----2--------------------------------------11-----1336222222434422225H786A62425441824JKLNKI321999898899999997333392-2CM2-425EC--IQ1431243445947555578A87878A7877555555555555524411-444A13-4F3333333625-T--1232-1-22312--------1--199712352-31111-1111-1-----11-1------------1------121----1---11-111-------1--2222111--------1---1--1------------------------------11----------------------1-----1-------11111--1--1----1-1-----3-------------1-343--21--111--1211112112222221--------------------------11957--11---5---------------------1-11111-111C755565DCCCEBAACB-CE9CDC9CCDCCBCDBDDDDBE77242CA9BABACCABBCBBB6CA7997A4-766666666666--31------------2155574623333233522222-2---2-22222322222222222111111111-9AA799999799AB2222222222-------922111133333333221----1-1-44311444145322--------1----151- -------------3------------------------------------------------------------------------------------------------------------------------------------------------------------2---------------------------- * d.112.1.1 IIA domain of mannitol-specific and ntr phosphotransferase EII
[ 564] --1-----------------------------21111111111---1--1333--------------- 2-4-222222222222222-22--2222222222222222222222222222-22222--222-4-2222222222222224------44442222--222--22------------------222-2---2222----------242222222222---2--222222-------------444--224-44444444444444444224444444444-4446666662222222222222222242222486266224646645446444424442222222222222222222222222222222222422222222228668666666646428222666242226222-4422-2682286626222-42--4-----244466222C22422222222222-6D456424222-2---2224222242--24-222224-222222222222--2-8-------------222-22--2--2----------2222-22222222-2254222222-22862442--22-4--2226-22-2-222--424444444222426-6--22442-444526882846848888--426222222222222-2-22-42---22-44A22-2-2-422222224222222222422-2222-22222262222424444444644-44444464444644444446662222266666666666666662444444422622222222222--22-----22222-2-222222222222222222222-22226-2222----2----42--222222222-44444444444444-----------------2------2222222222222222-4222222222222222222668666666422-- --------------2-22222222222222222222222212212112223222-2222222---------------------------24-222-22222-2-----2-------------------------------------------------2----1------------44-----323--22-92-2222- * c.55.1.2 Acetokinase-like
[ 565] -------------------------------------------------------------------- -------------------------------------------------------------------------------111-----------------------------------------------------1------------------------------------------------------------------------------------------------1-----1-11---11---1-------------------------------------1----1--111---------------------------------------1---11-------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122E9H-834-35A223344655546553567746332322333355234364333435343223331221243442343233123443-2233444452249761Bt6LPSJMcMJGIDFNIlYFbG**T4hQ*EGC9PDJSG9KGBDLAHeEMEHJ9B6*DB87RAJB68I86CEKn89AECD8BD38APNCDCBG * a.140.2.1 SAP domain
[ 566] -------------------------------------------------------------------- 1212111111111111111-111111111111111111113224211111111111111111211111311111121111112111111111111111-1211111121111111111111111222222222222222211113A5656663255555555554655554444444444443332211121111111111111111111111111111111111111112311111111111111111111111111111111111111111111111111111111111111111111111111111111111111111113434333334324213333222331124332243222222133331111114111311111212344211131411111111112-35112122111121111333322112112212131111111111111311113111111111111111111111111111111111111111111322322122224424222212334131211531131211223111111211111111111222211211112121211111333122332333334232222222222222222222222233111111313111111111111111111111111-131111111111111111111-111111-11111211111111111111111111111111111111111111211111111111111111111111111111111121211111111112-11111111111111121111111121112131111121111111111111111111111111111111111111111111111111111111146C51-111111111111111111111311111112211 3311443-F66-2221222222222222222222222222222222222222323222222233332313333333323433333322233222222222221444-39387476574343324653634U4-5573434434522344355354534434433355434536336AAB*CCBBAOCLQ2KF6622227 * a.269.1.1 FtsH protease domain-like
[ 567] --7--11251-2DHK5-211111-----1-31---11-1-31111-1--1--1-1211212-131--- -54242-11161-552-76-65--6-77676135454ABD-5MD2123-433669222--232-11-381-1---31--1131----14324541-2--11---641----------------1-------21-4-11--3793-3-52358L3112----253-1334412--11121--1211-1--1452232332B9C58J16D21321445726252215--14184454443111333224-C5656121422229--21122122311-21-2-1132--111141111-1-11--3-114311--11---4-1-1C26211-4312432E8FC515413B3111CA492H261131142B4-----2711211--1-3955DA23211322222221229-ABC98DAA5B3-833371C8-2-41B122A196721311EEEEEEEED966-A14------------1-11--41-----2-43--3C-2----23111412----22-834-255-762419--33323743281--4-4A12-1-2-------584415-17-2-25-811-2-641731--D251114111------1--2-----1-5-11-1141-3-2811---3-6368-42211425114-----2----------212123554152-341-5254-411226124535526722-22-14--25-13-2533-632-323231--2221212211---A--1--111112-4--------12----2--3-3212--3222133-1-2213--529811---------31-21312334---1-6161----2151--8---------------1-2----------1--------------1-2-2-----6--- -----1---------1--------------------------------------------------------------------------1-------------------------------------------------------------------------------C-----------------2---------- * c.53.1.1 gamma,delta resolvase, catalytic domain
[ 568] ---1111111111111111111111--1111121--------1-1121--1111121---1111--11 3431433233333332233-321142333332222243433347222321213332231133634334443222232211133323223334-2111--232324232211111112121111444254433434222443342336455424333434223422333452212221222131123311211211212222222323223222222222232211111112222222222221122222222212122122122222222232221223221111111111111111111111111111111111331111212111222222213111221111111122111222522121111111131322333422222222252332222233333333334-22322222332-3333333343333233333334333333333333322222332111111111111--11-11------1-11-353323333355555435455443455552445333342233323334344333331222234222222233233313433233264223222233324322324423222222222221111111112232232222352332222322222222222222232--23222------23323222333223322-3222332222322222222333223432212222222222222322322231-222222222222--12111113322324333332221111132223333323222324444444344443433421111221122222222222222233333333332222--22332222111111-111--------------------------32223222222322 11--111-842---2121121112321111111111111111111111111324121111111111-11111111-1111111111---111211-11111-1111-186------------------------------------------------1----21--------412444l33332BBJN1C6222---1 * c.129.1.1 MoCo carrier protein-like
[ 569] 11-1--1111111111-111111111111111-111121111122222--1111------1111--12 12111232222231-1111-12111-111111211112111111-2-12---1-122---1114111211112222221-2-12111122221211---1111111121111111111111111111111111212221111111222-11211--------11-2112-------------2122211-2224444444444444442222224442222223444444223222222222222213221323224425333656644232113344222111121111111111111111111111111111122211111--241111111212211111112122-1112211-22-1--111-1-1-123111111111111111111211111111111111-111111111111111211111111241111111111111--------1---11211111111111111111111111111111111111-111112111111111111111111-212111111111112111111211112----11-------11111111-11------11--121111111222212-111111222221-1-------11112111121-1111111111111111111111111---1112------22111211111111111-111111111111111111122211111111111111111111111111111--111111111111--11111111111111--1111111111111111111111111-1----1----111-----111111111-1111111111212211111111111111--11111111111111111-1----1-1112-11222111111---1111-111111211 3322334-F64122322443323232222222222222222222222223333A2332433323333633333233323333333311223222232222222544-34367D88AC87C6884AE6R8V*C-GBN8796K77DB88787777IA876634884347653K35437555*55556ECUQ3BB1242221 * d.162.1.1 Lactate & malate dehydrogenases, C-terminal domain
[ 570] -----------------------------1--------------------131--------------- 1352C22222222232224-232223222222333323223857-3443211---211--663277747G-1---1--22212----111---------14111431-----------------211111111-211142---E11233115--11------7111SUPC------------411-----539222222222222232HS875B2226682P3111111166111111111111111111111-1-24--11111--13--1--------------------------------------------------384J7656565467572764111A59--4115277442A71429A83111---53464232268GDDB879A9A97778778877A-DCBBABCEBB61AB9BCBCEFBDDAB84589A6866678--------1---1244------------11--21111-11-----142211232241112212333322-15333141122111----35144425121--13111-32-------32-241424-3-2--1-----11114121122227841-----------------------16--3422622-3-33334333444433444344--5121-------33254333223333323-2332222222232333332242233132322222222222222322342233-233333333333--3211111----32522---11----------22223323575444542335222223332---------152333333323222536676A222----1121-------------------------------------------------------2 ----331---------------1---1-----------------------------1--------------------------------------------------14-----------------------------------------------------1-------1--1121366441123113-11------1 * a.20.1.1 Peptidoglycan binding domain, PGBD
[ 571] ------2111111111--1----1111111112112153445411---2-1111-------1-----1 1-12----------------------------1-2-------1-1----11-11----------1-1-11-----1------------2112-4-------12-1-11---------------1-----1---11111-----11-12-11-11---------1-12121------------1------1---1-1-1-11-1-1---1311-1112-11-422------12-11111111111111---1-------------111--------------------------------------------------------4-1-----------1-------31---1--2---2----2-1------11-3-----------12211-23222----------1--------111--1-----------1--12------------------111-11-1--------------------------------1----------------------------------------1--------1---1111----------221111-131--1--12----1------1----------1----------1----------222221-222-21121-----1------1--------11-3------1----------------------1------------1-----121-----------------------------------------1-----1211-1311---------------------------22222211-2-1--1121111-11-111--211111---11---------------11---11-------------------------1------2-----------1------- 341143B-G67866722122222232222222232222221222222222324322322222222222122222122-222212222221122212---1211544-1ABnIGNNJGEHFCGMJrZBbG**Q5hRgEEGBTCKLGBIEB9RFGaHGGJaEDGHHG69P8AT7CGD2BC7k32233878627453EDCCD * d.142.1.3 Synapsin C-terminal domain
[ 572] -------------------------------------------------------------------- 3363------------------------------------3---3---6--2-2--------3-3------------------33333-------------------4------------------------------------3---------------------------------------------333224246444444434343374447544435333333333------------------------------------------------------------------------------------------34464888668677763446---556--37643353534334333334--33788953----33IAE553AI69E33333333333-A7D8949C44427669986AAA665-8473336666372--------2225-357-------------------------------1433344434444748444444444448474544445--743444544--435654533483-------334153844-545758A669453653336344-4--3-4445-6555443444444444653---65-746446555A66474744484378885---35431--11174347333334333333-3623633333336133223---43334432434344343434333311123335864686A7775---------3333--834-------------------------3944444443654345444---------5888777777BB7886644444448------I65677673333333355--------------------------6-34553455-7-- --------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1----2--------------4-----3---- * e.32.1.1 Phase 1 flagellin
[ 573] 22222222222222222222222211111111222222222222223222222222222221112222 -------------------------------------------------------------------------------------111------------------------------------------------------------------------------------------------------1222222222222222222222222222222121111111221222222222222222222211111111111111111111-111111111111111111111111111111111111111111111111112221222222212121221222112--2112222222112222221-111--111111111111111111111111111111111-11111111111--11111--11--1111111111111111111111111111111------------------------------11111--------------------------------------------------------------------------------------111111111-----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1----1---1--------1-------111111-111---- 65566673K787555556455555546555545555555555555555555555555445556565553654656565455666665776A5564C555555598F5695DCD9BC867CB9A9b*7k9U*L1MFj9AD6G87E96A988C88D8B9A967777675A7B767B76456*64656KDNI5G67686777 * d.79.3.1 L30e/L7ae ribosomal proteins
[ 574] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111----------------------1--1------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4523336-H583A8811121111111111111111111211111111111111111111111111111111111111111111111---1111111111111-8591337QXjXUTUPMMNMNLzoMsQ**w-yV*JOORaPNaPHMPLMNJMjPQPKNAFHHCECFU98P4IFD-WF4922222----1-1CDBBBBA * a.211.1.2 PDEase
[ 575] -----------------------11--211--11--------1121-1--11--------------11 -11-1-------1-11122-25332322323221213364-1-2111113111-21-2---1111-12111----------12-----------------1---12111-------------------1--11--1--32----1--11--1------2-1--1-1--1-------------1----------222221232223113----11222---1---1111112-------------------------------------1-------------------------------------------------------------------------------1-1--1-----131-11---1--11-34333-----AAA9C43345455------------7AB68A67236-2223334422237A1423243334224--------51112344-------------222-121-2--2----13352-3555456666554344886944442579749963455464244554332447----521111111-2176412522-1--1-----111112122212282-111111---------------1112-113321333212-2111112311111132121----741-------1--11----------------------------------11-------------------1------------------------1-----3787-2332---------11----54324212325245646566454454454---------1-11222222111113233233343------2---5566-----------------------------------------------1-- 31--773-8321335353575555954334332322232333344344782244795566554474472554865333545665465652A353221-12125743-5D4I112223876956BF9778Gc6-A59896785674657678C5F78763248254LKQDY2BA74-872631332E45A26C21789E2 * c.69.1.6 Gastric lipase
[ 576] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------222--2---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---------------2---22---------------------------11111111111--------------1--1----------1-1111111---------------------------------------------------------------------------------------------------------1------1----------------------------------------------------2---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------22---------------------------------------- 2222----844-44466AAAGGABCC8888888CCCEAAABAA888A88ACA8DAA877888666646669A686AAAAA68886644447464446444494MEM224-3MPKNKOJKIIKENWDFbJ**c-cMZCILEILIWIHIKJMMFKOJUIDL4AA24844A24U6832-22-----34MHFCAC8------- * c.55.1.3 Hexokinase
[ 577] 11-1111111111111-111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111122111111111--------111111111111111--1---111111111111111111111112111111111111111111111111111111111111111111111111111111111111111--1111111111111111111111111111111211111111113111111111111111111111-1-11-1---111111-1211----1111111---11111111111-1--12-2211-1-111111111---11-------1-1--111111--1--1--1111111--111111-1--121111111111111111111111111111111111-1111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111411111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111--1111------11111111111111111-111111111111111111111111321111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111121111111-11111111111111-1--------------------------11111-----2111 3322438-H5B388C1111111111111111111111111111111-1111111111112111111111111111111111111111112221222222122366613H5ICFFGGJABGBDD7QTBLC**L-NDNBC7EKDDNGBFF86E8DQ6GCCEEIA6CB92545E35G83556z43432B59815B3678778 * d.58.6.1 Nucleoside diphosphate kinase, NDK
[ 578] --1-------------1------1---------------------------1---------1------ -113D64444544475655-5L4466666665B9DE99BE546F54434332455215224342654EFB6111122222872-21112221-122---25232432-4111111111111111222222-121111111---411121111--111111111111111-111111111111333111--53834456455556556532777954453485545334357521----------1-------556633531315566223121325323--1-21------111-11-1-111----2--1--11---2-1-142583334564452AE33142282253-17217422132-122211--4211322111111221212432222222222222221-22232D34212-133311121111232122232322223-------------41----------------1-------------11-11124232222222222223334242223233222212223112224212412221211223322323211222--1-1-323413543444433523333331332121122221-12111111121--522221-----1-1111121121112-3111111-2---1------47333535ED8586945-F65968A698F99666566565333234454544554457446367566773-466547666445---112112----1112-223332122212--1--1---11--2-44544535333342334----------1112111111112233333333332222---1111111--------1---------------------------22112-2---1-23 ----341----1-------11111-121111111-11----------------1-------------------------------------------------------321---1----------------------------------------2211---12-----1--1--111----2----1-----3---1 * d.3.1.16 NlpC/P60
[ 579] ----------------1-------22131213-------312--1-11--11--1---1--------- 32E1322222222233222-242233222222A355648A235722223221422232225442444-1-3222226532242--111226328222--2726232252222222222222223222322442222331123523423221----11-----1--2333-------------162122324324545534545644454322223446557244222222312222222222222222222222322223222331122232222112--------------1-------------------1-----1---34222432232333231441222224113132643683313432224321222522322222422236232323222222222226-554346258D22433732574343272226222422433555555556224232222222222222222222222222222222133432322263333333333354593343233823498224335332234632244322222-22222222258222242-224224332322242222322222424----1---------------111--55332451-22222333322363332333433--25223------22222222222222322-222322222222222222224372B322222222222232222222222222-222222222222---3-21-2----2222-2222222222112222223222222332352233434344386622222222223333222222233243428232232222--32222222--------222-------------------------11-11-1---1622 ----G----------------------------------------------------------------------------1-1-----4---4-1-----B-159--4-412--5-----------------------------------------5------46-------8--3e------1---1-----4B-32 * a.60.9.1 lambda integrase-like, N-terminal domain
[ 580] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----127----------------------------------------------------------------------------------------------------6-1SllexodHNNKMPP**KxM**m5*d*JOPNkKQhIMRROLkNJ*NhUTRGNVMFDCDYCFPCLJ7------------------------ * d.15.1.4 First domain of FERM
[ 581] 11---21111111111-12222221--1---11------1----1----11-111111111---1--1 1-2122-322211112211-12113311111323332211-2112122-111212121--1221321121121111111-1411-11111111122---2111111111---------------1----2---1-11133---611------------------------------------12111---111222233232222232111111222323-1-1111111211222222222222221112112111113234111132-1-111---1111-1-11--1112-----111111111111111----------1-1211112121112211111-11211211-1--1231-112112-111111-111-----11242--123111------------211112111-1----1-11-1-211111-1-11211111---------11--111------------------------------1111-12-113332222222122222222122432223--1111123222--11-14----21-------1--222232121---11----11111221232322823-1--11111122111111111-2211111-121211111112111111311221132--1-21-------111111111111111-1-1111211111111111111112111111111111111111111111111111-111111111111-------------12231--112--3-32---11112111-11422222121211--34533---------1111121221111211111112111-------1111111--------3-2------1-111--111-1--1----1211111111-2-1 2211555-933544556536667767766555555556555555668766779888A556775445453455556555555666463335966878555544454418WJGCA88A68655675FB5F8Q*A-F8H4876A7876477567757768786697D855744765A83334R1214362237547A65774 * c.31.1.5 Sir2 family of transcriptional regulators
[ 582] ------2222222222----------------22---------222-2--422--------------- 2222442444444454444-44444444444444444444244442242---444444--4442666664242222442242-222222224-1122--2364244444--------------14444444444422222---2-22222222222222222222222222222222222222-22----22-222222222222222-2----222---2-22-------22--------------22222--614414---664444-22552----------------------------------------------2-2222-------2-2-244-222--222---424424222222222--2-2224444-4424444444444444444444444444-44444444444-4444444444444444444644444444444444444444444----------222222222222222-----43444222222222222222222222222222222222-22224223342222222422222222222222222226--------------424444522224244-2444444444442222222222444422544422244244444422244444422422--22222------44444444444442444-4444444444444444444444444444444444444444444444444444-422444444444---2---------222222222222-2222222222222222222222222422222222222222222-22-225444444444422222222222222--2-222222----------2---------------------------2--222224223 ------1------2--222344242442222322222212222222-2446366442222223--2222-24-2-222222-----------2----------4241--------------------------------------------------------11-----------22-------6--522--1----- * c.55.1.8 Ppx/GppA phosphatase
[ 583] ---------111--------------1--2------------------1------------------1 528-A11----21-23322-2211252222222434142227351116-A93-43-33--333-9227642----3221-331---123395-422---4524392F1A-----------------------2--211-----2-432443111--1--21311-1--181-1----1---2--------6-4--1--221322-2222122211221--2-112112211512222221222222212221121-441232433444423232-223---1-11111111111111111---11--------3311133311--324442452-326-44-4436122--431-22311---11111--123-G3221-----664894454455511111111112-74786546372-4433446444463721-321323212233333333145-2211------------------------------22312211114333334444433663333244641221111131241131112211321213222222221122312541--12-A2--112211-112134134A11-----111111-1----------1---121135112222111111211122122124---2122------23131111111111111-11111111-11111111112112134521222221111222211111---1--111111111111---1-----133132412---------------2222311--12532127313221321332-1--1---111121111111211243131332221---1-32774455--------2-1----------1--2321-311-11-1--1-------45- ----223---21226354244315244221332242-12121222234443BA645752333211111-11-112111111111111-18535535A46732-613-8T8A13211---1213145152AD3-335-22133332-4-2131--1113F22616731362A12K-2BG26333M525763AGA95311U * c.23.10.5 TAP-like
[ 584] --1-1------------1-----11--111111112211111222111122221---1---1112--- 1121421222221122222-21112222222211114211122211112111111112--321132354311111111112212221133343323-112212232312---------------1111111122122222111212122112122221322223212231222222222222433111111111111111121111111211111111112111111111211222222222222221111111--1111-1-111111-11111111-------11132222222222-------------111111111212-12111111121252112111211--1331122121111111121--2325322243333222242222223233333333333-3323333233323444224222332343222433331232222222222221353---11111---------------------2444421222112223214443113144452222212221111311211112211212211122222222235322325621134321555144434333322223312332333333333333333333344322223323533443222232222223212222-1-333211111122442222222222222-2222222222222222222222333333333333333333333222222223-22223222223211131111111113232511111111111111311131123424333435534455544455212123221232222222233444223333333322221131111111--------1-1-------------------------22322222221332 11--333-3111111121-13324152111111111222222211131111214-1112111111111111111111-1111111111111121111111121112-365336943823333339D3D2BS4152733225337333241422515336788172212562323D2443Q2223444481223265553 * b.49.2.3 Eukaryotic ODC-like
[ 585] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------ --11438-631-122111111111111111111111111111111111111111-1111111122222122222222122212222333-5212192222232323-571OPaSPYTMNNHNPJ*sHmH**q4yU*JMJKULPcLFPNHIYKHmIXOOLBIFGGFE6C69C12861454H764356DEM1I42-48592 * b.34.9.2 PWWP domain
[ 586] ------------------11---4312312--*q7-21325313Q-3797UPE----3------5--- 186-J-----2-----------------------------12-6331--22-21---1--76-2313882-1----1-1---4--1--1143-311----5--1HDE18-1222211-13333----------1-DFGKF---H2E3411-322------1---5196B2------------22---1----1---------------212211--1---11-11------9--------------------11--11---1------1--------------------------------------------11---111-2--5------1---24-------4-2---4-1-221-1--4-----1-----G1---------22111-2----1------------44374831331----1221222----2-1-2-1-12-----------1-----11-------------------------------1---------------111111--11111-23----31---1212--42----------------------111-1G5K-----1-----1H11437-245368d25-----------------------1-----21-7--2-11-11-1-211-1----112----113--------33-1----1--------------------------1--23-------------1-----1---------1-------------11---------118-1---1-1---------2233223---111111311122413-122-------------1------1--1--11211222--------222144--------5-2--------------------1-----2-11------4-3 ----SLE-848---5--11111-2-21---------------------11242464-2-1-1---------------------------121-12-2121----1--T*ng8A578B8566A96A66A5QwD2E9K8637947B758665I4485644B48A89555445255E3-ST8A482A51--21--822342P * b.80.1.9 Pectate transeliminase
[ 587] 11------42221424-2----2-3--1----9A1-1-1-3111411-12-33-1131221126---- 12512--122-----2122-2-----44444-1----1-11----12-31111122--11-11-1--264-32224322171--3244FLKE-E23----674336A-7--------------54342525544422234-----35AIAA7--222--1-21666JKBA211--21-3-1--111-2--21664646773237567557667653512115141112114231211111111111112-1391-1463132312115525143454A87722225223125138616-22222222222226555375551---87444233345613---6111-3--1561112331-11------1-3-22---------531121122-122----------3-3233242445-16221794467232-32-1--2-1221-1111111123334135------------3333233332332----11122--111--3342-2------24------113-----2-1-24-3--2323-22343341-3412333313312-32631677346652BCA677C65331321621--13856676161111111-11151-31114331711-1-3-11221-2-121241---4223------4412-222334253343-2323533432332432542212123853221222532212222312211321-322232222323--2-1111-----6242-11----12322--24------11--552212136----422632833332333111-1-------3--1123133112----2-43446544111-1-118------1-1-1--13---2533--1111------111299H ----14-------------------------------------------------1---------------------------------------------------2--22311---1111111--11-7--11111-1--11-1111-11-1111222211--1-----1-------------1------------4 * c.68.1.1 Spore coat polysaccharide biosynthesis protein SpsA
[ 588] 33333333333333333333333333333333333333333333333333333333333333233333 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111551613111-1111112111111111111111111111121111111111111111122111111111222221111111111112111112111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 43225432E55233523333333333333333333333333333233333333333333323333232232342435244233332444232322A333232297A2484633354225741F3ew4O3I*K-5Bd3446B44D333613B3484533435754333334535545444u44533G8993A73324344 * b.34.5.1 Ribosomal proteins L24p and L21e
[ 589] ------1----------------------------11111111------------------------- 3252622222222233322-23224522222433333357233633433443845222334452433565222222222----111--11111111------1-1--1111111111111111222-111-21-2222221121-24343333322111121133345321111111111112222211111122222122122222231111122111111113333331211111111111111111111--1-12-2---3411--1311211113431122111322223323231111111111111111111222311-34---------11-------1111111-1-------2--1--1-1--113222211111425453243344222222222224-34634624231121112234224524221222322312222222222433111321111111111---------------1111211211333333555435333322653333234373364232224423336436223334222222222223342242111-22111111111111112113343111-211111111111111111111111144227222223222333322333323333233212432322222233322433334344433-333334433334333333345433222333333333333333332223333222222222222222222222222222422332222222222222232222222222422222342622232252422222222223333333333343333222222222222221---------------111----1-1212221111112111111121111-111111- 11--211-3111-1233324463555522222222222222222223333347533313222113111111223222-22111111222231323154442-22221142245212-21--212211318S2-11422113224-11211312411122---13---311511321111J1111142552222241111 * c.48.1.1 Transketolase C-terminal domain-like
[ 590] 11111111-1-111112111111111111111111111111111111111111111111111111111 1221211111111122222-22112222222222222222222222121111222111112231222222111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111112222222222222222222222222221132132222222222222222222222222222111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111112111111111111111111111111111111111111111111111111111111111-111131111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1121111111111121111112112211111111111111111111111111111111111222111222222222111111111111111111111111111112221122112222222222222222222221-1111211111122222222221222222-22222222222222222222222222222222222222322222222222221233323333222111111111111111112111111111111111111111111111111111111211111111111111111222222222222222222222222111111111111111111111111111112-112111111112111111111111111111111 5433332-D44333355544444444444444444444344444444544444444444455344444344543455245444444554685596h55542255543354A6745464433144533639T6-547333333444344224-334754422546643643434434355O65543F7C869G5775546 * a.60.7.1 5' to 3' exonuclease, C-terminal subdomain
[ 591] 22-1--1111111111-111111111111111111111111111111111121111-111-1111-11 2222322233222222223-2222222222222222222243332233222233332322442232234422222222222222222222222222111222222222222222222222222222222222222222221112222222222222222222222222222232222222232222222123333333333333333344333333433343333333334533333333333333333333312111131113322112212223333333333333333333333333333333333333353443233344433233333333332333333336124224333443423334444122221222222222222342222222222222222223-2222222223225222222332222222222222222222222222222222222221111111111111111111111111112222223332233333344555332255564334222222222222233322232222232222222222222222222222333323333222322222222222322222222222222222222222222222222122222222222222222222222222212223222122222222222222222222-221222222222222222222222342222222222222222222222222212222222222222222222223223222232222222222222222222222222221222232322222233322222222222222222222223222222222222222222222222211111111211-------------------------11211212222222 12----1-2---1111111-22121221111111111111111111-11111111111111111-111-21211111-111-111111113111111111131111-13------------------------------------------------------1-1-------211112J1111251131321121111 * d.68.2.2 Enolpyruvate transferase, EPT
[ 592] 22222122222222222222222211111111333344333331111112222322222221111111 1111111111111111211-12111111111211111111111111111111111111112111111111111111112212111111222212221--232111111211111111111111111111111111111111111211111111111111111111111111111111111111121111111122222222122222221111122222111111112112321111111111111111111111111111111111111111111111111111111111111111111111111111111111221111111121111111111111221111111111112111111112111211211111111211111112221111112111111111111-11111112111122211111121122112111111121211111111111112111121111111111111111111111111111111122222233232222222232222222223222422222222222232332232222222222222111223213121211111111222222232223231111111111111111111111111111223323223333333333333433333333331-2211211111133333333334333433-33333333333433333333333322233433333333333333332333311324234443333111311111111112333333232333312222332232222232333333333333333333222232222333333333333332222232222222211311111111111111132111112-112111111111112111111111111111222 1111553-844321422223232343433333322222322223333223444422322232222222122222222222222222222273233722223222321263B4642433243535A25437R41354343365444445443335122352223H312322324621433F2332224822423454431 * c.1.9.12 TatD Mg-dependent DNase-like
[ 593] 2211323222222222--1----1422516861113323333342231-656511212232222-212 223-1221-1211121122-22--2322222232221222132313111---1111-1--1111112231-11111111111221211113211112--2518355253--------------142-11222124-----111119DA57632222132442663567541311111311111122211-214222222221222222221133222111112211111111111111111111111122211-111111111111111111--11111112111111111111111111111111111111111111111111-111111111212121123331311111111111121111111111111171224-1111312211111222111-1111--12-22222222332-4552664777673154553122228463333333333322112--------1111--11-------------152323222145555553322244553333335455556-144422333321341234431222111111111221235534233245111111222426311113713111211111112122222222242411331857638745444437644436266345--1631511111155343545555555555-55555555555555555554443322476667677777676675544545421533333333333112323223222225443333212111112111222222334521566545644555545663-111111-266642222254554222222222211111--1--111111111111111-------------------------1111111111112- --------211-------------------------------------------------------------------------------------------------2-----------------------------------------------------------------123226222656224-13--1---1 * f.34.1.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
[ 594] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-------1----------------------------------------------------------------------------------------111-24-SekbYakPJNGTRT*vLwL**nAvZ*RRPTdOUYNJUSQNVRN*QUWQQ9FBBDEECKABNFGL51------------------1575- * b.34.9.3 MBT repeat
[ 595] 22--1-11-------21--11--11--33122-----------1122422A31-22121-1---3-21 -2--6-11-------------1---2------32127665-7336822--4123--14--24235185771--------24----1111224----1---1---42111---------------111212111112222221271-111-----11------12-1----------------53123---4589999BADD7C99A9BIBFED99A97738734GIHHHFCC2888798888888888455791-17A-2111AA11BF14314334535456679BB88796686665555575555555493422244492644866675676871K5541216322-3331234222433138861-52--12111-----2-233---2----11111111113-21-11-11232-333135244545121121321-11344-------------1-1--------------------------------21--11-12221221133222343222324231221--222312112-112--12111241-------211-2--21-1112---111-33332352334345463----------1---------1---1--443113232113222312222243221233----221------44422232113233322-1221344243132222223455341314144434443344443411111112-411122222222--1122222232211416---2-------11--12111-1---22222222222112212211-1-1111--2223111111222344556544341111--22----11--------3--------------------------113-1112111-3-- -------------1------------1----------------------1------------------------------------------------------------2------------------------------------------------------------------------1-3------------- * a.4.5.1 Biotin repressor-like
[ 596] --------1------------------1-----------1----2-4--2426--2----1------- -12-8-----1---1--11-1---2211111-1----1211-117---2--16646-5----2214-883--444977---13-----1111-311----321A231-2---------------1--1-11--114444311143511222111221111111111213111111121112122222-----22222211212121211-1111223---4-53111111219BBBBBB7BBBBBBB999B94-1-11-1---11111111-556-2299986664444444444444466666666666664--777---4-1--1----1111-1-1--1444--133---2-422-13-1-2--1-1--2236663-----326447655666644444444446-99599F77786-7657555666554372723252552552222222262222576------------------------------5667-2222333333332222333533332233424622233383322322323226532351-------444442-1431141113636-526-21336556595461--1-111121-1-------12-1111211455424212344332133322233212---6558-------2--112-------1-------1------1--------1--122-1211111111111111-----------11111111-11--1222122----22721--------------1111111211254444456553555534441--------21111111112112144433334454333--4-1122442221211132---------------------------------------1 ----11------11111111111111-1111--111-111-111-11111-1-1-111111111111113111111111113332211113-1-1----1-1-11----121-11--111111134-213E2-22211111-11111-1-1--4121122331111-312-22-111118-1132323413221----1 * d.108.1.4 FemXAB nonribosomal peptidyltransferases
[ 597] ------------------------1--11-11---1-----1------11111-------------11 2212311111111111111-111111111111111111112222121111111111111122211221111-----------212111------------111112222--------------1---------3-11111---11233333211112223222222433322222222222311211---233444444553445445343333554333233422222273122222222222212422221-1-11-----1122111--------------------------------------------------------11-11---111-1---133-1---2--1-11---------------112222222222443442224444422222222222-22322322232212223332222245222222333322222222222133123341222222233222222222222222222222222322222222222222222225222222255222222222522222523222233222222222222222233121-1211112223----1-1---22222321-------------------------443343333333333333333333333333333--232333333344343434444444444-444444444444433443444444444444444444444444444434444334444444444443333222222222533333333333333333333333333333433333333333333433322222222223333333333343344444444444444443-----------------------------------------------------52-1 33--222-72212222222222222122223122232212222222332222221222221222222212322222222222222222212222222222222333-23234223211222223341234D3-435321221232222222332433232122211-224613322332S2223375561443342223 * b.124.1.1 HesB-like domain
[ 598] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----EEB-----74833422333333333333333333333333334444434443444443442233134132344-3433333322245434432334354AAE1M-BIYXPbVbSOLNQNSigMZN**TBeRlCONITPQTJBPMHKVRE*UNMKMAMKAA887I97R6GA7------------1-3----3333- * a.116.1.2 p120GAP domain-like
[ 599] ---------------------1------1--1--1----------11---1-2-------------4- -21-4---111----1111-11111-1111111---2211-33411--1--------1--111-4223342----1---111------2221112211112211431-2--------------121223111111111111--4-2114111111111111122114122111111111111----------1---------------111111----1--21111211212----1-----------11-1-----------1---------1-------1---1111-----1--------------------11------322211122121131122112121111-233-23312--1-------2-----11-----11111231-33213------------11212411-1--1--1111-3-1111--1-----211--111111111231111111111111111111111111111111111--24--111111112111111111111111111111111--21211221121313111122111-1-11--1113221-111111111122-112311312---133112111111111111111111112-12221131111213111231121121112121111--111311111112111121221122111-1111221111111111112121111111311111112111111211111-111223213333111--1111111111122211112111-11211111222121113121223311312231211211222112222211111111111112232222222111111113322341111111121-------------------11-------1--------111 45259E41BJ32333233235422322222344222332332322254235696542222221111111111111222221111111114833645333332155613G8RBDCA9C74D9885HP8I7Q*8-CAF5789897823985776378B97B8CCA7BV3356844D82776*55434FCAL2DF5576459 * d.122.1.1 Heat shock protein 90, HSP90, N-terminal domain
[ 600] ----2--------2---------2-22--2--37238--722524221-696G-3-----22-2---5 221--227---4-8---22-24--1-22222-24242-2--543-6-44----222----2-2-4-2---1-----445337---2-4-DCD--3-----3343-622----------------2464A9--7-4422-51--4-7-59988--22------442-6964--2----------4-------22-----33----2-----66-----5621---4-4--422-44446424544445-2322---4-3--44--286-7-7-2--2-21111143332866869698883333333333333-995637771-6--2222-42132-4-552-2---4-922D3--46--645222-222-243A2222-----242---5--2-2-3333333333------------32-----224---2-3-22-----4-44287888888---3----------------2-35-2--2-21----------24---2---2-----------3-21-22222-2--2-4-2222--428-C--C2622-235---4-62-5222-6H---8-3643--522A--C22-2-2-22-2245-424652448989B7773-2-AA--83B--2-24-86-A44-A-44-6--9-2--2E424-------2-6A-3222222224--22--244-222221-22-422-2432-22321-3242-2222-222-222-------5----232--1---------272222666332-646676A2-----43472-42-42-2--22-2-842-421-17-122-2442229252227-2254754448485--24----22--------6-5-2-5--5--BC22---4-4HA-5672-4-2------42- -------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1---------------------------- * d.287.1.2 Type I restriction modification DNA specificity domain
[ 601] -----1-111111113-2----------121---------------1---231----1------2--- 2-21432322222224411-13113311112221114333-324311--32-221222--11424277112-111---1--111111-----------1------1---1------1--1111-2--1--12---23332--1512124112-13333121-2-3-43851222-21122212-1-----2-2111111241-1-1-1325411-111122-2-11111144-11111111111111111211-1-12-1---221122111---122111----11111111111111-------------2111111111--211----------1-111----1----2--112-------1-------2-12221-------312---1---1------------112114-11-1--11-11----112-1222211122-11--------3--11223--------11--11-111-1--1111111-21---13322111211212222243324432324353411323132--11221-2142111212222222211443111-1112212111----21-21-454354------111111--1---11-11----2211-122212122222232223222222222---12-1------11111212124343432-1223232233253222221225112111111111111-11111234131331-122222222222---122222222221--1--------------12222213111213322314212111222111111111111111111111121123333333332222--5---1111--------1--------------1----------------------121- -1-1321-111--144634742311-453545653344243446455887IHaRDF966GIG1213223222211121214122111134316A562-3621-CAP-2B2F122333221-12223--17B211112-2121121113132-15232233211525-1-2824222114W54527ahn*5*O1-53423 * c.66.1.33 rRNA methyltransferase RlmA
[ 602] -------------------------------------------------------------------- -213F3132231--35411-15--38111113855566B8341-132--222734--3--6532656DLA5-------5---5-------1-------------1-111-----------------------------1----------11----------------1--------------432-----1265555566625555557655575553453547899A98112333333333333322112286425A22948AA22965394342321114333322444444444443333333333333356221555412-38222222232526--2333--11-2----6712--3--112111-3-1-5332-------345--11213155555554558---5--5-336--A6655657679A311312553125456--------2221--11-------------------------------112-5ED888888884656677AA666645A7DEFE81166523212424676321111152----------111-32---11--1--2------1-11----1----------------------------1143112-114131111-11111111111111------1------54631526665644477-66676327676455565546864511-6356565666566666454345553-333243333344---1-----------435---11----------444441--22-17767456835444-345---------1222122222233221133333333-------1-------------------------1-----------------23---5-1-1--- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------8-----------------1-----1---- * d.190.1.2 UTRA domain
[ 603] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1---------1---11211111------11--------------------------------------------------------------------1------*6I356111111-2321419K3-4342221312421-21--12915133akJH********tlV--31-----3---2----1X----- * g.31.1.1 Tachycitin
[ 604] 1121221111111211222122211--121--12233222222---12-1---232232221211--1 -16-2112222----1111-13--1-11111111122322-2-111221111222123--43313355554-----1121-2-32111------------111-1------------------1--------12-22155---2151212223211111121311-22151111211111221-11122-221222222121222322121111221222-111------121-------------------------------------------------------11111111111----------------------111223----1-13-311221222121--21112221212-22111221-12254--1------2444--243313----------1-33233222-32-21122312121-31-2-152-2-12231111111112213211-----------------------------12323-12-1244444432222223133332344745651222412233326431327111211222222211234328412-1213-22211211114132443A5152--2-------1211111112222133212-434-1513233323333336322334---22221--1111111-131111111211-11111111111111111111112111-1111111111111111311111111-211111111111--12-----122132212------1---1----11111111113144442443223214232-1111-1113--1111111---1222232343332222--2-113321--------1---------------------------1111111111-31- 3311113-A36-3262524222524224433222222222422554222345353222222222213222222223222222222211262252522233352312-1K2735467642A43447A1C4Kt827684543844551443244373543544C46354645B78752787T69743D9HH4FAAD66648 * c.66.1.17 Spermidine synthase
[ 605] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 224577A-8321532359435556464666566463775767766634453455455333335-1222---122122212-111--43336152343323253468-7C3dSpRRaNHHFGLMKLQFNDt*P4QQjIL9ESILNJGKGJFPJEPHKFKGRbEGMIQHJCEHHMJC3951O66457CCD95I6565A767 * c.47.1.3 Calsequestrin
[ 606] ------1122222221-31111------1-1------------------------------111---- 565-5----------------------------------1----252-231-211--1----323-154113222143---13-----6695-5-----13-11412-4--------------------------22223---3-113---11111---------21421-------------1-2245-31----------------2422-----111--2144444118--------------------24314311414322236113-21-11-1------2222233232222-------------222---222-2--37----------21--16525--2-1-6-1------3---2222--1---311---------1---------------------------------1111--------------1-----12------------1----------------------------------12-1-111111112111------11111---1--------1112------------1----------------------1-------------------------2-----------------------------1-21-11-3-21-------------------------------2422-3-2222211131-212241222121233233133322---3332333333233323111-2221--122222222222-----------------21111-2-------------------13-------------------2--1----111121-2111-221111111111--------221122--------1------1---1--------1-------2322221242-23- --2322E-422-223C8C9D9A7C8DE33333322211122221125656ABABA7666555133111-1112132111123331234467983443332123866-498d9D9DHF979BFABAGBI8NvB2B9M86BAB58769BA8AGA8I8CBC78JY8HL9B8491754D7224a44468L79D9542356584 * c.1.8.13 YicI catalytic domain-like
[ 607] --------------------------------2221-------------111-3-------------- 3433222212222222222-22222222222222222222332422222332333222222222333445222222222221222222222223222--23333333332222222222222223333333333322222---232222222222222222222222232222222222222232222222222222222222222222222232222342222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232322222222222322222223222322323322332323222222222-222322222223222222222222222222222-222222222222222222222222222322222322222222222222222232222--------222222222222222222123323233333333333333333333333333333333333333333333333333333333333343333333333334343332423332222322333333333231111111111111111111111111443333333333334444333444434334332-1333312-22233333333333333333-33333333333333333333333333333323333333333233333333332333333333333222322222333333332333333333333333333333333333333333334333333332222122223333333333333333332322333222222333333332223222222--------------------------23322222222333 -----------------------1-11----------------------1--------------11------11-------------------1---------1------3----------------------------------------------1-----3-----1---31---2------2--1--4--2---- * c.5.1.1 MurCD N-terminal domain
[ 608] -------------------------------------------------------------------- ---------------11----1---1-----------1-----12---1----1--------1----1-11-------1---------332--3-----1111--11-1--------------------1----------111---1--11-----------------1-------------------------------1-11-----------1--------------1----------------------1-----1------------------111-111--------------11--11111111-1---1----1-----1111111-1-------------------------1---------11-1-11-11111-----1-------11111111111-11-11---1111211123232212----11-11111--1--------------11-------------------------------1--------1---11-------------------1-----------11--------1---1-----------1-----------------2-2-------1--111--------------------------11---11-1----11111-1-2121-21-1------111--------------------------------------------------------------------------------------------------------11----1------------------1---------1--1-----222------------1-------------11-11---1-1-------1111----------------------------------------1--------1 2333436-E642669444444556464444444444445454443435655575674546645474444566745553564444444435A64665675753764D18L9GRMHLMJCDDFDDCcTHOEw*I3PKQCBFFGEGEC7DDD8I7EGDGFFR799WI779A67ACFF739D6I43414FPMY-QA454A9AA * d.151.1.2 Inositol polyphosphate 5-phosphatase (IPP5)
[ 609] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----2------111------------11---------------------1111-------------------------------------1---------------3--yz*mouZMHJDKVMtYFiO**n-kVxAKKGeOPbOARLIDUH9fQUQWbMKNqfZGGkKUYCJPG------------------------ * a.135.1.1 Tetraspanin
[ 610] --1111-----------------131122322123------------1121211----1-1----1-- 1122522222222222122-22222222222222223222333333323222343233223332424345322222222222323233222321112--211213223333333332223333334422432423233333322263443332233222122343344431112111112215431133133333333333333333332333333322222222222223222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222225354555555535333444434445223433433533236432232122221333222222222223222222222222222222-43434332222122222222222222322222222212233333333443222223322222211112222222222222212222222212222222122222222222222222222222222222211221221212232222222222222222222234523332434332333433324222211431111111112111121111112221322221322222222222322222222222221-13232-1111133232323333333333-33333333333343333323333333233333333333232331211333311322222222222111122222222222232222222222212222222222222242333344454444444341111111112222222222222222322222222333311222222221111111122211111-111111111111212111111311212122421 ----11-----------------------------------------------------------------------------------11-----1111-------------------------------------------------------1----1---------3----21124111--1111---11----1 * a.60.2.2 NAD+-dependent DNA ligase, domain 3
[ 611] ---1--1111111111-1-1-1131--112111121222233122212113321-------121--22 332121-222211122211-13--2311111132222333121111--1112233112--111-1-121211111111--1-111212--111-------2-1114111---------------2312122212211-11111315122113112211131133213323111111112111211111--211--1-1111-111111112211111-11111111111113-11111111111111-111111111111-1-111122-1-1111111111----11---------------------------111----11-13------------22------1-11111111411---1111-2---1131111-----123221-12211211111111111-22121121114-1111111111111111212111112241111111122211212-----------------------------422111111-12222222111122221111112222222-122152-1123222123223231311111111-1242-3231232122112-223222233222312111--1-----1----------2122233132122212131222222222211111112----112------11112111111111111-1111111111111111111111111111111111111111111111111111-111111111111-------------43213------------11-22222131111222222223323223222---------41112-11111222211111111111111113-331122---------------------------------222-11--1-11111-- ----545-----11243534333344411111111122222221115322354433322444663232223143333244233433233242343A2221222445-5S6N7A88A5565444647384S*8-G8F235384463344544219464455AI3C7C3223576I528A5*43464D9CW5748675789 * f.44.1.1 Ammonium transporter
[ 612] 11-1-12222122222-3223213322332121111111111111111-----111111111111-11 2321611111111244444-46223544444345666476233223222111333313--334233355321111222-11222222222222222---1211121233111-11111111111344334334332222211-41222322222222221112222525212212222111222122221222222222222222222222222222222211111111-2411111111111111111111----------------------------------------------------------------------32-11----------1-44-11-1-1--21125332341214----2--1232222211111433472322223211111111112-43233334252122232222222313222122222312211111111222-23221121111111111111111111111111122222111113333333222224423222212322323322443222222222433234221332222222222223246333333534441222232222333335262221122221112111111134434113322222232334444243333433334331-12233------33332323334343433-333333333334233333333333332333333333333333332232222213333333333331122222222222223122221111111-222133333222223333233232233232222222222222233333333333333111111111122222221332222------------------------------------------1---2222 11--111-311-11132221111121122111111122221222221111111111111111112111-2111112212212222211111121151111111212-111221112211---2-121124R1-452-1-1111---111112-11221113111142413922211122X2222232541322242221 * a.7.3.1 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
[ 613] -------1---------1--1---41131221-----------211----4-2----------1---- 1351C-212221--CB877-7E44DA7887898EGFCDLK-74C6612-3233561-3--456-93BBA94----------13-----------------2-1-3241----------------1---1--3---79845---341-2---1--111------1112-21------------41422------11111111-1111111----2111----11-1--1--44-----------------------1-1-----11------1311111-------1--------------------------1------------11-----------------------1----22-----1---------3--53331-11-41FBA3364526522222212221-452653285CC-89953567CA6859-4224543232582222222211325243------------------------------5494-57755CDDCEE5664499G8AA9947E9KDCF81-664115444324D1355---11-11-----111226252--1---11----1121312--346378-2-------------------------11--1-1---1--1----1-1----212---1--1----------13112212221211122-22223122222122212234342134-2121221222212112511111111-111111111111--1------2312-2652---------------554454313271878866A7398892557-------------1------11112255554444------------11-------------------------------------------------- -----11-952-123423272344333112211---1------11123373485443334431-2-------1-------------11-43324121-1-113-----C-2----13-1-1---1-1--24--1----1------1----1-1---1-11-2-----112-1--3-31---2-3588CA4321-4344- * c.69.1.28 Aclacinomycin methylesterase RdmC
[ 614] 111121121111111122323222-----2-1132-----11134-12-1533-111-112-1-3--- 1-1-8--12231--45344-4411544444436454B8NL-7392311-321764215--65317135672-------1-1641-1234423-311---1122121121------------------1-------33333---133664665223333333335226653333333333333312451134-1111111121111111333312111113111122222131-22222212222222232111---12---------11-----1111---------111111111111-------------1--121---112-16333445424222331222514--212--22421-1112---1121112511-111113396712-4236211221222224-44144131542-BAAA66577A8858221236534433332333333222123221111111111--1111111111111-----1531-52114678977822228886443323A4F4D6311223334114155841412221211111111----5412----11-23112-112321111--1-12311-----------1---------111----13-121132-3111-211111111-1-1------1------2332-312222222223-132322232222333233456522111111111111111111141112223--211111111111----------1--11224222--31-----11155545261123122227565447451454---------11--------2-2-14412122111-------2111111--------2---------------------------13-1122222--21 ------------11243335342474533222211111111113334335345321233222222111-21-212-----12222211147232533332212111-13-5-----------------------------------------------1----21-----9-----344a222442---3-2523322- * b.45.1.2 NADH:FMN oxidoreductase-like
[ 615] --------------------------------------------------1-1--------------- -----------------------------------------------------1---------------------------1------111--3221---5---16---------------------------3---------2-1----------------------------------------------------1----11-11----------------345521----------------------1----------------------------------------------------------------------1----------------------1--1--11--------------------------------1---------------------------------------11-------------------------------------------------------------------------------------------------------------------1------------------------------------------------------11--1------------------------------1-4-----------1------21-1------------------3---55-1---11-41114--1214-31--111--------27--2113222131-2-A9AC69A1-156645533245-------------------------------------------------1-------1-1------------1--1-----1--22--1---1-------------------------6----------------------------------------- 3211**B-B993125--1-211113113322121322---1--2-21--2443211-1-11112-1211121D4B111222CA58X212162-3661-115-11-1154CWBFA8977B445639D186JuB297G3454645634697158784627839159A454C8N6BA41514611-847*x*-*A-3EB985 * c.10.2.6 Leucine rich effector protein YopM
[ 616] 2211321-----------1----152232596--1232333331113125556-1212222----213 334-111---1---21111-12--1211111132221222-21212111111---1------11111231------------121211223222111--2527334254--------------141--1112-33111--111118FD6A9532221324535735675414111114111111211111112222222221222222221122222111211111111111111111111111111122211-1-11---1-11--1111-------11111111-------------11111111111111111111111-1-111111111212121113331211-1111111112111111111-121161223-1111322111111222111-1111--12-11211211342-5552664897783154454233339472222222222212112-----------------------------142321222145555553322244673333335466666-144422333321331246331243111111111231245534233256111111142535411112513212322222222122222221243411331948529755444426644436265345--1431511111155342646666666666-66766666666665666665553322476667677777676675654656521533333333333112412112222225344333212111112111222222234421555555643666535662111-11-1244442222254454222222222211111-11--22111111111111--------------------------1111111111-12- ------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------121121----21--2--1--1---- * d.58.43.1 Mechanosensitive channel protein MscS (YggB), C-terminal domain
[ 617] -----------------------------------------------6-4A23--------------- 2-4-1------------11-1-----11111-2----135--5D-----------------1----11--------1---1-------2283-111----2---1---------------------1161138-6-2222---6-965-417------------91382I----1----------------1--2-2217221C4-47-5-----1-33-25-1-11-1-7-111-------111-------1------------BC1--------212----12--1-2-21111-11--------1---------------6113-----2-12-1144--1-11-1-R1EJ193516B-P-1AG---1---1-----------9132-----------------7------2-1----3--2121---56-------1-2--3-1-------------21------------R-------------3-95--31------72336611------13-------24-112---2-1--1-1-6---216--1----------2-15-31-5-28--1-11-1--211-3J51----5811--------------------------1--161---11--4161-2--122---713------11--------23----11211128---1---16-H8-2111-1112-1---21-1---1------1----22322-31--111-11-1-----P--------22-19-2-------------1---11---1--8111-------91-1632-----------1--711111k---1---1-22---------6---------------1---11-----------------------53----------- -3--*1--7-14--1--317-1-2-72-----------------12-f---2----1*----A---------11--2----625----22------5----51-6*11--142-4D3-----1-15-B13G3-222-1--11-O--1---*--3-21*2--2-3--*--1512--3-2-1------M36-4-----BD- * e.8.1.4 RNA-dependent RNA-polymerase
[ 618] 22---111111111111---1--1-1111-11231111111111112-1211211112111---1-11 1211111233322223222-22--222222222222222213231112111-11121111221211122111111111111121-1111112-4123--3342223221-------111----2322441333234333233332-2222213311---1---12----1-11----11-----111221314222222222222222243322222442323222212144322212222222222222222121-112-1-2211--13111122212122123222222222222222222222212222122222223313133333333434432232221242132333224225542244533221221-1111111111211112112111221121221-1111211111-1-22121122122211-1121121111111111111211-1-11--1-----1111--11---------112--11-11221222221121333311113333322212221-1222242112232222222333334145535224223-222211224-11213232122224142432332111222211111-111112221232222221212223333222222232222332--51213-------2321121111111111-11111111111111111112221122211111111111111113112111-1-222222222222--22121122222-212111112111221111111111-22122233332222411122211111111111111121111111111212222222222221-2---111111111111-1311--1-221-111---11--1211136366454442312 2222222-412212312222222222222222222222221222221222222222222222222111-11122211-111222222221122222211121222122628475544523355457253AR628492444A35622433353484546313534341223-12542122V4343242342322233221 * a.60.2.5 Hef domain-like
[ 619] ---------------------------------------------------1---------------- 3331222222212122222-22112222221122222222222221111111121111112221211222112221111112122343111111111111111111111222222222222222111111111112222222221222122232222222222222222222222222222222222222111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121213333213131112221111221-2111233221322212221211122222211111232222222222222222222222-22222222222122222222222223222222222222222222222222222221111111111111111111111111111112232233333333333333333333333333333333323333333333333333343333333333333223343334444643444441444444444333324242222111111111111111122122443333333333333333444333332443442-2333311211133323333333333333-3333333333333333333333333333333333333333333333333333133333333333311232222233334333333333323332333333333333333333333333333333333111111111333333333333333333333333322223331332233111111112211111---------------------11111111112211 1111222-3-111111111111111111111111211111111111111112111111111111111112111111111111111122211211111111-2211211111121122111211152212461-1111211211111111-1121111131111111-111311211222L2223323351762242221 * a.173.1.1 Poly A polymerase C-terminal region-like
[ 620] 432344444444445433443443A9A7A9B9333222222252222222322223233323332269 -1-------------------------------------------------------------------------------------------1---------------------------------------------1----------------1----------------------------------------------------------------------------------------------1--------------------------------------------------------------------------1-------1---1-----C--------------------------------------2-----------------------1------------------------------------1----------------------------------------------1----------------------------------2---------1----1-------2----------------------------------------1------------------------------------------------1--------------------------------------------------------------------1-----------------------------------------------------------1-----------------------------------------------------------11-----------1------------------------------------------------------------------------- 76699862J764488666747578875775776878577747777765674374636445658788887788888886889999898888D96979758778699976D9HFGCHE8977CBCBHG5G7vtF-ECI6965DA8EA5AB87B84G5C89C9BCB98A799CD78988878e88787CGBG6IC899A9A7 * g.41.3.1 Transcriptional factor domain
[ 621] 11-1111111111111111111111------1-------------1---111111111111-111--1 -12-4-1----------22-21--1-222221----111112-22111-1111--11---1-21311323-------1--1111-111--11-1111--12---31-2--------1125555-11--1-2----12223---414113----1---------2-1111-------------1-21111------------------2----1----221-1--11113211-11111111111111---1--1-11111112111111-2-------1111----1------------1111111111111---111----2--111111111-1-11111----11-1124-2--122111111111211-11-----------111-1-11111----------------1---122--------------1-1---1----------------1---12-----------------------------------------1111111111111111111111111111--111--1------21--22---1------1-1-1121-2211111-1---1-11131222211113313----------------------112---------21-------1-------11-121---1212------11-111-1111111111-1111121111111111111121-1---1111111311-1311--1111111-----------------1-----------41-----1------------------111-22221---11-----------------1---------1---1111111221------22----11--------2---------------------------111111111111-- 34--642-512211333744566556644466533343332335343234678733233122121112222222322222233323---263353811111-1111-ABFtLJLCQBADBBBDCMEBQC**G3OGVIFCDHECBDBDEFDFABOECBDPGJC9CD22E343127M132--11112854665S2377DD4 * c.50.1.2 Macro domain
[ 622] -------------------------------------------------------------------- ----1---------111----1---6------1333-451-321---------1-------------2--------------------------------11111-1-1--------------1---------------------1--1---11------------1-2--1-----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111-----11--1---1--------------1-22-22-2--21-1--2---2------11112-------111111111-------1------------------------------1121-------11----------21------1-21-21----12-1--3---2--------1--------------1---------------------------4--------11111-----------------22----1211-1212211111121111211--------------111---------------------------------333--22-----------------1---------111111111111----------11---113---------------------4-----2112-22-1---13222111-11111-1111-----111111111111111---------------------------------------------------------------1 ----783-63A-336HCKBJDDEYPYDA96989A798988899888CEBHCHIHGFGB7777446-72-4--137-----244344142JfKC8EC8777735542-4p3N111-2-------------------------------------------548-67613111--6-3636O6459Dt***K**AAGDEHD * b.82.2.1 Penicillin synthase-like
[ 623] -------------------------------------------------------------------- ------------22----------2-----------2----222-----------2----22---22--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---2-----------------------------------------------------------------------------------------------------------------------------------------2------------------------------2----------------------------------------------------------------22------------------ ------4-C69-76644436444444444444444444445444446D44648444445444466662278656696467666666---AEB489866668A6C8B-CB-sOeeeYRFFD8FEEPUENH**U2OHUAJFCEBEGGAFE6AGDBNKFBIPPUY2MD8BS9BZKOQM------------2-6--44HFEE- * c.43.1.3 Choline/Carnitine O-acyltransferase
[ 624] 21121212322243331222222432231221222334433454523433333535233542112133 3322211211211112211-111111111111111121111112112121111111111111311211112----1--23343343333333112211111111111111111111111111112222222222211122111132322332222223322222222222323233322223211223322222222222222222222222222223432311222222232222222232222222332322322223222332222323---2122222222222222222222222222222222222222222222253233555555525333442333233321323233334223644445233131111111111111111111121122222222222-112111122221222223222222111111122111122111111111111-1111111111111112222222222222111111111111111111111111111111111111111111111111111111111111111111111111111111111233333332333332444333333434322534443333333312121121133333112222324323322222222222222222221-1222211111122112222222221222-2222222222222222222222222222222222222222222222222222122222222222222122222211111233333333231-123223222322211222222222222232222222111111112222222222222221111111112111122322222221111111121222212-222122211122222222222122323331231 11--111-31----1-----------------------1-----------------------111111111111111111-11111111111-11111111-1111-22122111-2111--11122328A1-312111-311111111-11-2121121--1311-114A11-22112I222223121-11232242- * c.26.2.6 ThiI-like
[ 625] ------------------------1--11111-1---------------------------------- 1111122333332321-22-23112222222333332121111221111111233122--1121411233211111112121111111111111111--11111111111111111111111111111112111111111111112221222111111111112111111-111---1-11-21111--111111111111111111111111111111121111111111111212111221112211111221211212221111221111111111111111111111111111111111111111111111111111111131333333323221111222111111111111111111111111111113111111111111112111111111111111111-11112111111111111121111111211111122211111111111111111111111111111111111111111111111111111112211111111111111111211111111111111111111111111111111111111111111111111112111111123111111111111111111111111111111111111111111111211111121111112112114212211111121-11111-1-11112111111111111111-111111211112111111211111111111111111111111111-111111-111111111111--2111111111111211111111111111111111121111111112111111111111111111111112111112122111111111111111111111111111111111111113111111-111111111111112111111111111111211 12227A6-4231664536422224443455675645222222223456768787D8676468A45232144424244244355354554354324355541363522676F6778695655464B8392Ik7-98836757477266462852D387757GC55564B44D36382455F341-283445214524123 * c.15.1.2 DNA ligase
[ 626] ----------------13221--221231521227--------5A2H52187------------1-14 11H14---222---1---------------------342211-32----32---112---351-51-35B---------1--2-1-1---3--1--1--2--3391M14255555512-11113------1-1--7769B333B4F9ED88978AA6A7AA9677CDEJS15341115144111121-1-132333333332234223432223222232223211213457122222222222222211221---11---------111-------------------------------------------11---111-334211111111-1--1--1---21---21-13---2-221132231-1294J2111------1322---1111311111111111-1-1-1324111-2--11------1-3-121---1-1-1-11111111---1-411------------1----11---11-------221-----13223212111122--1111113112-1--11-11-1--113-2-1331-----------1--1-2118435-532642241475367544CADAcv15--1--------------------------11-11----1-11-----------1------11-3------12-1-111-1-1---11--111---------11111111133-----------1-1----112--------122222222222-------------117-1--------------------------345543622421132112-----------21-11111--2--1-1------1------335555461111111143-----------1--------------11-1111111-322 -2112-2-9213443111311311314112212311111121211121111334112121123112222321111221222111122331221231322213235214B3865436941-4243862357L22447165244454-423453183343151214322322423538344H2113296763221411225 * a.118.1.16 PBS lyase HEAT-like repeat
[ 627] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------1-2-----------------222222222-2-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----2-7------------------------1-------------------------1----1---1-1-1------------------------1-----------1----------------------------------------------------------------------------------------------21-----------------1111111-----1111211111222-121---------------------111--1---------------11------------------------------------------------------ 4*56777-FA7311B22111111211111-111---1111111---21222212-111-212111-11-1--1-1------11111111454225544446578B7-HKxEIQGJOMEDCCEDDRJEQDX*M4MHSAGCBJEFLE9FBC8FDDKDFHHJ9A887753766F6AC41637C66517MPZ*1yP9Dgt*o8 * d.129.3.2 STAR domain
[ 628] ------------------------22222222111---1111111111-1111-------------11 2112121133112122222-23112222222122222222222224221311111111112232322111222221111222211111111111112--253523323411111111111111231129311131211211111233423411111111111331322111111111111111111111111354555335324754422222346411142223333334212222222222221232332323222222222322222222222222222222222222223222222222222222222222222222213424333454323223442222211322121133331233111111131313855311111125553246743B22222221221-211212312381211124223313235181111111-111111111111121211111---------114411521111121212966712111133323342222333333233333323332311121111112231222222432324424412233322232121252222133222131233325221211111111111111111112111211222222322312222222222242222322--11211------23221333333332333-3333333333333233334343222223333333333233333233333332-222222222222--16323332D54225231111111111-111111111111113222222222222222222322122322222322222242223223343322211111-1211111111111111111111-1-111111111111211111112111121111713 1----------------11----11--111---1-1-----------B--1-1---------1-1-111-1-211-1111-111-1111--1---1111--11-12----821311-1----1-11-21232---2----11-1--1---1---1--1c1211111-------1122112-1-1-1114111--12--- * d.226.1.1 GIY-YIG endonuclease
[ 629] --1---1-7224--27--------24431193------------------2KE-----1-1-12---- 344------------1-----2--1------11-----11--38-------------2--------12--2----2-----3-----1--------8---6-1--D12----------------3-97J72-6-6F2244---1-65F-C8DG1--------1-C-4B25-5-----6-----19----1--------51-----11248-------831-23-------3----1--1-22---22-432-1------A--1--JJ---3-----------22--212-----1--1---------------44322222-4E11------2--3-A322-3-E-82-3-2--443E146-22--112-23--B111---------231---4112-----------------1---4--------4------------1------2--------1------1-------------C--7--B---------------122121111111111111221111111111111-11111112113111111421--3-12123311--9--3H351331-2-----463116JA69847-8-1-----------4-71-----5-1-B---1-32A31797A2633B-93662-H8444L--37216------11--4--132K121311-111-283333327111111-111-18E7--811--4-1S7S811--32111--3*rm5***uF2E-----2-221512114-4111122-12-2324--------11-2-1-2231-42233212332----3-------S47447-----4511313111------2----------1--1------------------------------2-3-313-2-412 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-----------------------1---- * d.58.57.1 Transposase IS200-like
[ 630] 221222222222322211111111222222222222222222222222111112111111111112-- 2212232222222232222-22222222222222222222222222222222232222222221222222222222222121122211111111111--1111122-22222222222222222111111111121111111113222113-11221121212112112111111111111111-112211-111111---1121-1211---2--1---1---11111111-1--1-1-21111111--1-111111111111111111111114431111111111111111111111111111112111111111111112-321111111222111112221121211111113122211-111121-111233233334334333333534333333333334-3333533333333333333333333333333333333332222222222222222222222222222222222222222222222222222222122222222222222222222223222222222224222222222222232222222222222222221-1111111111112121111111111111--1111111111222222222-2211222221211221222222151222222212112-2222222122222222222222222222-22222222222222222222222222222222222222222222222222222222222222222112122222222222222222222222222222222222222221252212222222222742222222222---------2----22222222222222--12222222--------1111111-------1------1----------------11-1 1122341-1---112221-1322121211111132221111111111112111111121111111111111111111111111111111*11211222221-1111211321211-21111111221216F3-32511--111U-1-11-81-b1A4133421512-212433311111811111212E11111-1221 * b.85.4.1 dUTPase-like
[ 631] 11-11123323333331121111111111112111111111112123121222111111111111-22 2233422322222323333-342228333332888832344655322222224323231123424245542222222211114111111111-1------1--11221---------------------------333332112411141111222111111111211221111111111112111121132111111-11111111122111111112221121111112211111111111111121111111122111111111221111111111111111111111111111111111111111111111111111112--1---------1-1------1-1--11113115362133411-11--111333122222134451114224133333333334-45244443396266656656667646111344555554611111111411131341111111111-------------------3112311111134434322222333533332334211311111233111124214111141342111111111112211211111-11111-11111111111112211111111111111111111111111111221111211113433322222222222222---1123------13111112221211122-2222211222212222221222111111111111111111111422122222111111111111111-111111111111253111111111-111112222222111416676877677877445511111111131111111111211122333334441111111-111111------------------------------------221221211111-- 1111121-31--1111223333332332222332222222-222222221222333333333111111-11111111-1111111111121221223122111353--5135A3254-221231212318H4-42522123-2321212-311214334133742155253561114414---35B5AA274112-2-3 * d.15.9.1 Glutamine synthetase, N-terminal domain
[ 632] ---------------------------------1---------11-11--111--------------- 323-2---------11211-12--2211111222221111-2121---------------212-2112221-----------111111111111111111111221111111111111111111---------2-54566---421111111111111111111121111111111111111233221111111111111111111111111111111111111------11------------------------------------------------------------------------------------------1112211111111111111111111111111111111111-111111111311222432222333342222222222222222222-23222232222222222222222222222222222222222222222222212221111111111111111111111111111122232223322222222222222232222222222222212222222222333222223111111111111222122435332222222222444233342333336221111111111111111111111111333332312222233333332333333223231-1222211111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111211111111122322111111111111111111111111131333333333333333331111111112111422222222222222222222111111312222222222222211111111--11--11---11111-11111-1111111-1-1 1---1-1-----33344333333332322222244433333333222322333333332222212111111112111-111111112222224232111223466B-5B26A767A74463356A7394Jy7-96D555373664555447445479676D644452554A22643799e6655597AB3E77553332 * b.122.1.10 LON domain-like
[ 633] -------------------------------------------------------------------- 2222322222222211111-12111111111122221233322332322111232122222231333322422221113333322222222222222--22222222222222222222222222222222222223333---3322222222222222222212222332222222222223111132254688B8BABA5BAABBA456666ABB5443432333333653333323223333232233232223322212222233222222222222222222222222222222111111111111122222222212448533333334344355355533432433234443432223555212222-322211111111111111111111111111111-111111111121222211111122112222222222222222222224222122222--------222222222222222212122222222222333333344443333444423333222322222222222222222222222221111111222222222222222222222222222222222232222222222222222222222222222442222222222222222222222222222221-2122211-11142224332222222222-22322222222222222224442322244444444444343444222222222322222222222222222222222222222222222222222222222222222222333333332333323331111111112232322222323322322222222222221222222222222222222--------------------------22122222222322 ------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1-------1-11--------1---- * d.175.1.1 Penicillin binding protein dimerisation domain
[ 634] -------------------------------------------------------------------- 314-1--------------------------1-------1--1---1----------311---1111-----111-------------------------1-111--1---------------1-----------111-1---1--------11----------------------------1-1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1322------2111111-1111-------------111111111---1---11-111----341----------11111111-112--2---------------------------------712-----344443334423321555534442-1----111-------------1----1---------------2-------------111---2----------------------------------------1-132-1-1222211122213112121---------------------------------------------------------------------------------------------------1-1-----1------------------------------------------111-----------------------------11111121111111------------------------------------------------------------ ----536-213-434FDEB6CBBFEGFAA6877CCC8CDCCCC678CA67ABIE78675544A33343352333433133344474333OKAD7A775734C6688-5UDNBI67674555546B9367Jh6-75646555655435434455D843647BG4F71B7564LG2H-762G233B5Km**B*R66RNGPE * c.69.1.5 Serine carboxypeptidase-like
[ 635] ----------------11---------------------------------41--1----2------- 132-6---222---22211-11--221111115111--22121111------2-1--2--11114-2355------------------6641-1-----54-718331------------------------1--111-1---3-1------------------------------------3----11---1---------------14--11---------1-------4--------------------------------------------------111----------------------------11---111----11---------------1111-2----1--------4------1--1--34114-------1---------------------------12322--52221-211123--121---4364------------11------------------------------------131----------1------11---------------------1------1---------1---------------------------------1----111125----------------------------------A3-4-21----11-------24--3--------------------------------------------------------1--1------------------------------------------------1--3----------------------------A------1--------------------1-----------111-11-11---------------------------4-------------------------2----2-222-23- ----543-----774IEKJDFFFEEEAAA9999998AA9AA8A888NLGHQRNTDCIGGGFG469454266A53655455676777334PhOEXYZDAE9G9N959--O-D------------------------------------------------443-7AA48987-----53-311191eTZgHXN76SfabA * b.29.1.2 Glycosyl hydrolases family 16
[ 636] ----------------2---------------1-1-------------------1-1-1--------- 1221111111111111111-11111111111111112222211111111111242111--11112121111111122222111-11-11132-111---2412113231--------------2---2113312111111245117312111111122222212-1111-222222222222212--1132211111121111111212112111111111111111111232222222242222411112111-121111111111131211112112-11131122-----1--111543342333132221122121112223333333332323144232312311135232133322221---111-1-12222-3215423324222222322222222224-54444E34443133363333345324222112231314144444444343244241111111111----11-------------25632133122111111211112222121211141121112331129217242211122217244543323131311135113263745771313324215113131133-1-1-4-221-1-------11121314331314122315BG734353351622223--21334------2611272377438383418237255434885233236653222273313132251435235433322327-422232222424--311111155652237632343234344436363574612-11133575957288A82A9A111111111224242424441133112332222253231181111112------------------------------------11113112111311 ---111--1-----------------------------------------------------------------------------------------------------11111111--111131-1-381-122---11-12--11111--1-2112-21-3------51-2--12-----1-2365-21-1----- * b.87.1.1 LexA-related
[ 637] 333333323333333322222222211111111112211111111111122224222242211123-- 1121111122111111111-11111111111111111211111111111111111111111111111111111111221121231322445412341--131112221211111111111111111111111111111111111132321111111111111111222211111111111111112222112234346343435445432222253413422221222223332222221232222223222311111211111211112312231111141122111111111111111111111121111111111111123333333334334326333433233232242133341211121122112111111111111111111112111111111111111-11213213112111111111111111111111111111111111111111111111111211111111111111111111111111111111116111112211111111111111162121211111132512121112111112111211111121411112111221122221111111111111122111111211311211232221111221532321422124223232222222222222221-111121--11122233242222222222-3222222222222222222224322343222332233332322423222222-222232222522--2111111111111122222232332222332211211111121122222331223322431111111111254222222322221121522111623311211111111111111111111111-111-11111111111111121121212221211 1132112-733211111111111111122111232211112111111111111211111111111111111111111-211111111111211111111111121211415232321233232584431LN2-322324323222-434323-42322234C24234212422322233N3433343351373221112 * e.10.1.1 Prokaryotic type I DNA topoisomerase
[ 638] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1113BE8-E58-668614345453322332222236344445523334554133A6555665413534243434512-12544445642169162363772519473CDDVMOJIKMHCCCJJEXRBTD**Y4hRfDDCFOEHNHGKIFCNGDMCJGFFCIP8FAE9983A7bEC55588788H36GD94C926AI9B- * c.15.1.3 BRCT domain
[ 639] --1-----1113213--1----1-1-11211--12---------121-2-2----------1--1--- 7222222322222221133-34112433333155554334-221111133234-3-1111114-312112-2--------1-311-312214-2-----11123234-1--------------2----1--111-33311---114436446--1142222112225846-1---1-31--------1-1423A9B8A66A78676661-1112787-2-311121122359--------------------11-1--12--2-211---1-211-----1----1--------1----11111111-1111132---3331-31422221312221-244----5-2-1-33-24449512112--121132-11--1-----121-122-11-1-11221222222-43463234-51-3111112-1234122---111111147111111114124323-------------1111112111111----1112--1---14442441344422447775383252-2311333112-1-311--21-2-1--31--11-----1-1112-1143-34553123332221222122213-12--1-11---1---------1--223312---11111312111211112212321--2--1-------2312131-111-------11--2----11-2-----13123111-2---121121-121--2-------2-212111212111---111111----3-3112121421111-121---11--211-2221-11221---11-233111-1111115433111112311114222222222212--1-111133-11---------------1---2----1--------1---121111121- -----16----1213141--1--211122-1111--1--11-----11225425121111-1---------------------------121412-----2--424-3B-P6A89576766768D78C8Gc8178D79548856568674763D654844CF47843433811553231521-427BBD-E9431-13C * c.68.1.15 Exostosin
[ 640] ---1----1111111--1-1---13--1--21-11--1-111-11112-1232-1112121---3--- 123-2----1-1--1------2--14-----13121235211-111-1----311-----1-3---13121-----------22112-2113-2--------312-311---------------111112211-1---31---134324333223333354334212234221142222112-----43---411211132-223322323232233-1-22-111111-25---------------1--------------1----------1-----------11-----------------------------------1-1143333222-2-3-1--1211-----1-1---22---------2---31----------57B452132424322222222221-42525A42141-3225575436334412-22221113241111111122112331---------------1---------1-113--3-1343-2655577534443377555525776528512-12623-131634-441132211-------21243321121222113111133322122133243341--11-------1111111111-221431124213-221--1----3-1--113--1----1211------2122-322554223242-5224332433424332332132123313233333333333333333133322-211-111111-1----11111211131123-------------11------2---11655653443211312342121222211----111111-2-1112111122211112-1-----22-----------------------------------------------3-2 ---1----------189A5867377731112222321212222212768ABEHE88565324----------------------1----BD59172-112--------6-4----------------------------------------------------11----------2212322294P*i*9p*4----25 * b.82.1.2 Germin/Seed storage 7S protein
[ 641] 11-1--1111111111-111111-------------------------------11-111-111---- 443-1--1111-1--1-----1---1------11111111-----11-1---111-----111-111---22222222-11121111122221222-1122222222-2222222212222222222222222323332222242313322111222231221123444212111112111122222111211111112112111221111111111111111111111111111111111111111111111----------11----1--1212121111111122222222222221111111111111222122222-12114111111121232221111212-13113233432521422221-22433222111111--2221112121111111111111-1111111112212111221222111111111211111211111111111111111------------1111111111111----1-11-13332343333433333334344443443323342233332333343332223222343333223211233323211111--2111145465555644544144111111111111111111111111133553242412135555565555555555555112332211111144444444445445544-4444444444454444444444444444444444444344444444444444243444544444422232222222222343233431332222322333333332224233343333343433333222222222245463444444555222222222222222213222222--------1-1---------------------------1--1-1112522 ------------1122222233422232222222223222322222222222221222222222332222223332223221222222224222222222262436-23------------------------------------------------------1------2--11-----1--112113341--5344- * c.1.10.4 Class I DAHP synthetase
[ 642] 11212111111111141111111121112131111111111111111111111111111211111-11 1131211111111121111-1211141111112111112213233221111122321111113141333322111111212151111111111111---2222242212---------------1111111111112222111112222221232211111111222333111----11-1-122111111121111111111111113222121111212211111111231111111111111112111131-111111111111111111111111111111111111111111111111111111111111111111113213222222222213221111231311212175121111221111111113222222222226552222222222332333333-22422423442142233326533343-22244333332233333333344222121111111111---------------11112112123221-2443421222222333332314233344--2211321122314311221111--------11111111111111111111111111112111111312-11111111111111111111111-33211-3-2---1-------1--------------1111------1-1-1--2332222222-122222222212222222---2-----1-111-1111111111-1---------------------------------123-1---------------11111121111-333333332132211111111111113---1-----1----11111111111111--12111111--------1--------------------2------11222111113111 ----431-211-111413242233314222222222222222222222222322223221112322322211322221223222221112431222432232-343-332C9J9GD96664778GC7C8If8-B6F4876E777657844764F7D67A32843234634D4462122-I--12242452221-1---3 * c.1.9.6 Hydantoinase (dihydropyrimidinase), catalytic domain
[ 643] ----1--11212--1-1-1111111--1-1-----111222221213211121--11-111---1112 -11-111111111-11111-12112211111-22222244121231-1-221122111--111121352211111111-11121-1112222-211---1311121312--------------111111111211144142221-2121222--111---11-2-1112-------------233----1-12223233332333333--22123332332-3233333334222222222222222322321111341111222112221211244533331112112222222222212222111111212112221113--1222222222121122222221-111-112-11121---11----1111-1211------223321-12212211111111111-22523422161-32223343431322111---1-11--122222222-2222322------------1-11-1111-11------11221111-1222222221112222222211223343412322432224342523341-211---------121131221-121-212221222222112112111122111-2222211111111111122-33222--1-121222222232222222212111--1--1------23222222232222232-3222222333222322332333222212222222222232222422222221122222222222211-1-----2222-221311111111111111122212221112233334343133321444-----1---1----11111-1-1111222222221111--1-11--11--------1----------------------------111111111-111 11--431-624-113CAG8F796B97H7746785754655565886B5AEI8IBBC7D7888342222122124343133233333222263A5372232121574-243------------------------------------------------------------1-----433422121964CB84-155692 * f.17.3.1 Magnesium transport protein CorA, transmembrane region
[ 644] -------------------------------------------------------------------- ---------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------1--------------------------1--------------1------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1------------------------------------------ 4455GC8-832-54521122111111111222311142221122121212223112314221123323-22222232-322244333333331534111232277D27JGRRVXdPRJHFIGFImYEaJz*J6YHmEFICJEIJDBHGLDQHBTJUHHL7JIIFC9AN97M9AE53779E523569LJW4S957699AE * a.207.1.1 Formin homology 2 domain (FH2 domain)
[ 645] 2221222211111112212122121111-111222332221232111111111422222221112211 -121111111111111111-111111111111111111111111111111111111111111111111111-1111111111132222222212111111111112111222222222222222111111111111111111111211211111111111111111111111111111111122222221111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111132212444444434323223333322221331311222222114343123121111132212111111111111122222222222-111111112211222222222222112212122222222111111111111111111311111--111111111111111111111111122222222222222222222222222222222222223222222222222222222222232222222222222333334333331222222222222222232323322222322222222222222222222222222223222222222222222221-2221211111122222222222222222-2222222222222222222222222222222222222122222222222122122222222222211122222222222222222222222221222222222222222222222222222222222333233333222222222222222222222222222222211-111111111111121111111-1111111111-1211111122122222221111 3222334-5125223123222224331223322232122212322223232232122222222332121311323111212333333232332232111111122114444132223332-13-323337G3-525-22-51231--11-3--3---1211114332132122343222E2212345273633342344 * c.26.2.5 PP-loop ATPase
[ 646] ------1-1---2-----------111211-111111111111--------------11--------- --1----------------------2---------------11-----------------1---1----------------1-------------------------11-------------------1-------------------2--------11-11----------1----------1-1--------------1-------------------------------------------------------11--------------------111-1-------------------------------------------------1----1-------------1-----1-----11---------1-----------11-11--1---------------------------311-----1-3-1-----1-----1--------------1-----------------------------------1----------1-1-2111----1111----------------1-1-----1111---------------------1------11--111-11-1---1--121--1----------1-1111111---11----11111--11-1111---1-------2---------------2-1--111111111111-1111111111111111111-----23--1--------------11111111----------------1------1111121-------------111---1------111--1-1---11111-2------------------------1---------11------------------------------------------------------------13-- 3434686-C6514455534455764663344434453333343433454454454444443432222212233233222221121134367353565555323465-7c4QIHFIEEHFDB9EBUJBQCm*G2QDTBEBCHADFB8EGAADB8GC79BEFMCCBC97D8BY76DA19AGt99A79EBDG4EO689B9AN * c.66.1.6 Arginine methyltransferase
[ 647] 22222222222222222222222222223323225242222222224222222222222222221211 1111111122111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112222222222222222222222222222222222222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111--1-1111-11111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 35433433B34344333452333333333334333333434433333333333233334333333333133253363-6333333333336433333333333436337483534575563433568434X3-347532835332235344937484423AL833Q7323G34744393Y33385XB5J3692383334 * e.29.1.2 RNA-polymerase beta-prime
[ 648] 11222221111111112112222211111211222222222222222211222224222221112-11 3331112111111111111-12112311111132221322133322212221222111113322243232211111111222222321222213221--232232221211111111111111122222212222221222221234433332233111111442233331111111111111111122211122222211121211111111112111111111111111112222221222222111111111111121111111111112211111111111222111111111111111111111111222221222121132222222221221111111212111112222112121221122211332111111111233241112221211111111111-11111111111111111121121122111112222211111111111211111121111111111111111111111-111111111121222222222222222222242222222232243-1222222222225222233222332222222223233133232222222232222222212334323331122322222222212122212222443323222222343333233333333333321-2232311-11133333333333333333-33333233333333333333333322333333333333333333333333321322222222222112222222333332322333333222222222222222222332222222223222222223232122123222233333222331111111111111112312222221311111111111111-11111111111111111-112111111112222 1111111-211111131111232343122111111111111-11211111121211121111111111-1111111111111111111112111112121121111114193542211111-1121111141-11211-11111-1111-1111122131221231211111212222192222222331222121112 * d.115.1.1 YrdC-like
[ 649] 22111-11111111111124211122223133112121111112211212442111112121111-12 -1114--1111----7222-2211312222223131-3-A1-2112-2----346-----42211-42331-----11111131111111111111-------12-121--------------122222212222344331113454644442222---1113233555411--11121-1123222322225333333332333333225534333222222244434354322222222222222333331---11-----11--111--------11121113-------------11111111111113--------225237444444424224773222331233224366643233233332211-31322412222344341111111111111111112-11111222131-21121222211133221112333312211111111422-313211111111111111111111111111111123121222223333343333344343333334342332-255325232333322223222242222222232353224A5358357588A124335345522422727---1-1-1111121111111-211133434221223233333323333232332333--22232-1-11132232123333343433-2333433333233333332333223342222222222222222333233322-3222222222221--111111222213422---1--11111----3333323111414444366634333346511111111111--4332332333333333333332222--2211111111111111411------1--11111111-1111---1111111111322- --------2111-------11-1---1----------------------111-B----1------------------------------------------------2222----------------------------------------------------2-31----11-11222V2221-2242-211221322 * c.8.1.1 Pyruvate phosphate dikinase, central domain
[ 650] 11112221322333222413121243333225212-1-11---634652444323423213---2--1 1441311111111111111-112211111111111112224241122212112321111122212122221211111111212211323232-4222--122223421322222222222222222233233342877772224263562333255233224335845532222332221221-121551221222223322232333221111222112111111111122-1111111111111-111-11111-11211111111-1111121111111-221-------------1111111111111111111111123122111111121221332111123121121232233231222222112412222235317223432113333322222221223-2232232324214444533443543322232222333231111111111122322------------1111111111111111122-3--32222111111111111111111111112112111121412211314321331121321221121--1211222421431-1114232334433411222223221111111111311111113221411112112111114112231122232222222--13111------21223111113232211-111112223212311111211111221121111111111111131211112112222121111121111222222222211122-12121111-111111122211222121113131211211311111111111132112221211211211121211143331161222222----------1-------------------1------2211211-23322 2-1111--413-123113-1442234-11122221225454543424132321213323242-------3----2------221-1111---1---111223-23--2514111-1-42-41-323-426C3-22212--332231421-4111-1--513236721-2-213H2111--1-1-2-12R221-131461 * b.81.1.1 UDP N-acetylglucosamine acyltransferase
[ 651] 113223212222222232222227222212222212222222233233111-1222222222222-33 123132-1111---11111-11111311111112122246243322212111222222--225132554351111111----222222222--111-111111111121111111111111112222222222222222211-22112111211--------21112211------------11111--11111111111111111111111111111111111------1111111111111111111111-----------------------------------------------------------------------11-------------1-----------1--1133-15--122-------131211211111117352152243411111111111-445335333421211121332223241112221111425--------211-232211111111111111111111111111111112111196582111112111111351111111162A88121113434562234511331122211111112235221AC52263-35432-434141512112122A4--11111111----------22332112211211112222222222222222222221111222------32222222223233322-22222332222322222232222222222222222222222222222222221222222222222111111111111131231111111-111111111111112111113333121112221111111111111112222222222222222222222221111113-111111------------------------------------1---1-1---2111 22--333-411322222223444434322332223222222223222233342422222222211111-11111111-1111-11112223222222222232223-32466645433455334771B2Ee5-7264444434543345433444535548933333746744443321A1113232782522232223 * d.142.1.4 Succinyl-CoA synthetase, beta-chain, N-terminal domain
[ 652] 11----2111111112-1322111111112111-2---------------111--1-----221--11 1132321233321232333-32113433333322222373242225211221322225--222232344411111111-1114113331111-1-----1111111111--------------12222222222211111---42211111111111111111111111111111111111122111---21322222222222222232332322211212111111112211111111111111111111-----------------------1-1-------111------------------------111111111----------------1-111---1-11-132--111------1------11-1433311111214331122211111111111113-11211312343134412323341111131212111112122222222211111221111111111-111111111111111111111211243454554453434433774444245396B761144211122421155224112122222222211211121322-1--21----222331211111123-22111111111-1211111112111211221221222232222222222222223222---3222------21111112222222222-2212222222222221222222222312222222222222222111111111-111111111111--1222222222212422-----1-----11112221222222232222222222222222211111111111113222222222222222222221111112-222222-------------------------------------1---1-1111111 22--551-521-55534324444565533333333333333333333433444443333333311221-1321113333321111112248446442222342232-32344433331222132542235W4-3154222422332222322322212234722222634C33335253h2226484873862132224 * a.103.1.1 Citrate synthase
[ 653] 222212222222222222222222422432341-1111111111111111111122222222222--- 2222123333311333333-3322333333333333222222221112211--121-1--21112221112-------2111211233111-----1---212112211---------------2222222223233344---2233222221222222222211222221111111111112222211-212222222222222222222212222122211222222243122222222222222232222-1-11-2---221211--11------111111111111111111111111111111111111222111123443333333323223111333211332-232334363234522121112123223-11-1222222232222222222222222-22323324222-2222222222223223222222222222222222222212223-----------------------------22222133333223232222222222222222222222212222222222222222221222221111111---222-2424343433332-2221224453333332321111111111-1111111122112223322112-1-13222222322223233233---1422------33332333333333333-3333333333333333333333331213333333333333333322233331-222222222222---1-----111121111111111111111111111111111211222222211222211111-1-1111-2222222222222221111112111----1121221---------------------------------------13211121112211 ----111-----1122222222232322212222222222322222122222221222222211-111111-11111111111111---24222221111212332-22-223342-2211212522529J414563222522422322242142222211822321211324221321611-332135222224343- * c.57.1.1 MogA-like
[ 654] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------GbdgVULIBGEILK**DpG***1*7*5MCCMDLJF6LIKGyD9*GAKJKCBJDvX-EOGG-Ao-------------------------- * d.211.2.1 Plakin repeat
[ 655] 11---11111111111-1111111--------1-----------------21---1--3---11---- 1223311111111122322-22113422222233333333343452212222222322--55414533442111121112124224333333-211---1215212412--------------1112443222352113244432G53533333553333333333333323222223222233133221233333333333333333335533333333333333333345333333333333333333333-2-22-2---2222223221211111111111111-----------1111111111111111111111143333454565636322883333431333323-44523224345454-12222322233333254444334433544444444443-22222322423-4333333433334332233233333333333333322222533-----------------------------32222223322222222322222244222222223434311333212116222322232221222222222312221242111252443341323224223222224354443322222212111111113222332241232232211221121112111111111-22443------42222222322222222-2222222222222222222225222222222222222222222222222222-2222222222221111111112212224221111111111111113332322222223333333333333223322222222212222222223221222222222222222112144334411111111--2----1---1--11----111-----23223323331411 --------------------------------------------------------------------------------------------------------------------------------------------------------------1----1---------------------1--1---------- * a.4.5.42 FUR-like
[ 656] -------------------------------------------------------------------- ----1---------311----2--1------111111233-1-11-------1-------------12-1-----------------------------11--1--1------------------------------------1-----------------------------------------------1311111111-111111112223111-1111--------11-1111111111111111112-------1---11------11-----------------------------------------------------------------------------------------------------1111------111--112-111---11-11-11--11211211-----11----1----22----11-------111111111-----1-------------------------------1---1-11121111111122211112222-22111223--11--1111211-2-11--3-----12111111-1---------------1--------------1----------------------------113223312133333333333333333333431--111-1--11133332343333333333-3333333333333333333333453333333333333333333333333333-33333333333311-1---------111212222221111111111111111---2422223223233432222----------2223222222222233333332221111----11--------------------------------------------------111- 3313335-J7523266755556599853343334446444334323756779CB5585555533443434443333314433333344499473333333243A9915G7G5767B666647A7HD4C7e*9-E8G37659777737881866Q676675HL45564D52555672553X5454464566555787653 * c.23.5.2 Cytochrome p450 reductase N-terminal domain-like
[ 657] 11--2-221111111221--1--332221-11242--12111-22--1-9FCC111211121212-33 28935-33333-3-34433-353345333334566643332586--111----11-----75938536684----------31--11-55443333----433452234---------------434443444536557812-4111111111111111111121111121111111111113333322-17-11111111211111124111-1115555-11------54------------------------------------------------------------------------------------------1A514333333323254222111332-15128-JR4423681955732213123332-----343333315767722222221222166655557223-3223333223434654255355666432222222212221445------------------------------2222-2111111111121222112422221112323422222255233354422215111233-------1114553PAH142211112118A78B9B6A444499251-------------------11-12--1111112--111111111111111111111---3111------211111-2331211122-321232123131322222211111--1131111111111111111-22222--311111111111---1---------21221----11---------11111-11111111111111111111111---------1111111111111111111111111-----161666566--------1---------------------------4555516111-533 ----222-42----2----------------------------------------------------------------------------------------111-24242222212222222232334G2-245221232223222223223232242372322-----1221-111H1113----1---2232221 * c.23.6.1 Cobalamin (vitamin B12)-binding domain
[ 658] --112-11-------12133-1111221325212-111-2-111-1--11424-31321122111-11 -------1222--111111-11--111111111111--12-1-21121--1--122------11--111-1----------11----222-3-------1------1-1--------------------1--1----------1-12122211111111-1-111-1111211----11-1-1------------------------------------1---2-------3---1111-1111-11111--11-1---1111--221--11-------------------------------------------11------2-1-222-121-1---111111-2-1---1--1-2-11-------1-2----1-----------11--1-----------------------------111--------------2-----------------------------------------------------------1--------------------1---11---2-----11--1---11--21--1-----1----1---------32-1111-11---------1--2-----2-21----------13-111---1-21121---1----1-1-----------1----1----1-----------1----1112-1------1-1---1---1-1--1-------1----------11--1----1---------211111111-1----------1-----2----------------------------1--1---1-----1--11111111111--1-1-----1--11---1-1------------221111--------1-1---------1--1-----1-1-------11--------- 4345A6A1833188453548669645844965546565643646667577575934394468347455-556864441446667535894C8363E342436554512C6LCA986E6FADABAEGBJ7M*C6ECHAAA8F9AH569A8BG79B79A9AAJE8BA77B56P67E814B5t75796768A4BD7747577 * c.37.1.23 DNA helicase UvsW
[ 659] ---4-3--------------2--4--------1----------1--1--52-1--------------- 3GQ---------------------------------------1------------------------------------3D6-1-D23111--211--122---4-------------------21132322212-----111---1--------------------------------------------------------------------------------------------------------11----------------------------------------------------------------------25--2222211111-2--1221---1-1--2-AA221112M1--------9G1--------1-212---122-1--------------1----------11---111132-21--2-112--1-1-------------61--------------------------------434--11-11----1-----------------11231--11-7-------H----21-1--1-------666-24187549864899881***U***1Aghth5C4725534224414-2-------45258--64-1114-1-1EBCDC1FREEFDGFRSGjE---2164------4---4--3333333333-3323333333333333331---22---333333333333333313313333--111111111111----------111912--333333334443113-----------11121-1--1-1-11------------134462222247455--------------127133--------------------------------------------------2C1- -----2-----2---------------------------------------------------1--1----------------------1-----1-------1-1----1------------------------1----------------------3--------------2---1----1-------1---1---- * a.138.1.3 Di-heme elbow motif
[ 660] 2233222222222222-22222231111121133433343443222224344432222223222--22 2221611122111121211-1111111111111111211124431111121121111111451132333421---1--111222222211111111---111112111211111111111111-111111111111111111121212222222222222222222222312221112122122222---22322222222222222243332322223222111111113311121222221112211111112111111112211222121121-1111111111121111111111111111111111111111-111123211111111121222222111112112123322333332432112111222222211111123111122422222222222223-112112123121122211222134121112142222111111111111111222322211111--111111111111111111111231122222222322222223355222222329334211222331221212212222222222222222222522112212222322221232232222222211122222222222222222222222222222222222212222222222222222222221-12222------33222222333222332-322333333333322222333322322333322322223333322233332222222222222221222111112222222212221212111122221111111111222222223222222222211111111112222222222222211111111111111112122222211111111-------------------1----1---11111111112111 1111111-311-11112223232454422221222222222222224234424422222222224222143232344244433342111-2121212431111111-12122111111--111112211161-111-11111114111-11111111121111-1111121111111116111-121352211111121 * c.34.1.1 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
[ 661] 11111-11111111112122211121113-21113111111112211212332111111111111-11 -1125111111-1--------2--13------222213221-12121222212331-2--212221323321---111211221111111111111-------11--2111111111111111122222212222344331112142422221111------11213432------------23122213211111111111111111111111111111211122222233211111111111111222222111221211122222221111111122221112112222222222211222222222122111111112221122222222222-2223222322222322311131121122222221113344412222224432222222222222222223-22322232242-2222233332222222222233332221111111143314344111111111111111111111111111111242212222233333333333443433333433323321244424332333323223222262222222232222213521233232333123324444522322422-----------111111111-1112223362212232333333343332333333331-2332311-11153333335556566655-5555655545555555555344333334433434433424334354444443-3444444444441111111112222123321111111111111113333323111314444454533333333311111111113335333333443333333333332222--1311111111111111311----1-1-11111111111111---1111121111332- --------2111-------11-1---1----------------------111-B---11--------------------------------------------------2-----------------------------------------------------2---------111322V2221-2243-21124233- * c.1.12.2 Pyruvate phosphate dikinase, C-terminal domain
[ 662] 444244444444444444666662IFHCHGJF2222222222822222222224244444446642AG ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1---------------1----1-----------------1----------------------------------------------------------------------------------------------------------1---------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5524995492227896667777777777767677766777677767455555555654444463555534554445555576666676769B6A8B8664576A865898GCGCDDD85579A8AA7B4Y*E-JCT4798B88A439645B85I798B99B8C77D67BC835A75557e98774CBEU6QD4346563 * a.74.1.2 Transcription factor IIB (TFIIB), core domain
[ 663] 11--------------1-1----12112---2---------------12112211-11111---1-21 --5----1----1-------------------1-----221----1-12---441--2----3-2-----1-----------------111---------3-32C1331---------------------------1112---1-4121114321121122121121111-1-2---2-----1---1-----11111------1---1-----11--------2111311----------------------1512211111233311-11----11111----111------------------------11111111114----------------------------12-------------------4-1---------11-1----1---1-------------111-11------11---1-------121----------------------------------------------------------------------------------------------------------1-------1--1--------------2-----1--1--------------4332DC-1-----------------------1----------1-1-1----1-1----1-14-2---1------------------------------------------------------------------------------------------------1-----------3-----------------221421----------------------------------11------11-11------------------2211-------------------------------------------------2-- ----112----------42312111-2------1------------1--52-4212---------1--1------1-----11-----1--1--121-1--------2E3uQSQVMVMMHKNLOcXGSLh*V1SKjJMILSJJNJCNOIEPFEXMJFIX9JJW5AC5458647Q-11B-------231O-5274A2791 * d.92.1.11 Matrix metalloproteases, catalytic domain
[ 664] -----------------------211112131--1--112111211111-1-2--1--1-1------1 113-431655523253122-26--222222216464774723333445533-834141--1341212342222222321-113221112223-211---1523225332--------------132233322233444441113142232221211211122221244321111111111112412222-4323333334333343332333233333434311333333442232323333222323344411231132112112211-1-21-22211111111111111111111111111111111111111111111223212223422121213311113121-1421152112122112222--11-33222-----322222242222212221122225-46146441442-222133344121343-33134423243---------1111533------------------------------121311111364466632221AA944444247574143-26432313243332-4-5212121111111124143412331213-2111--1-1111121222211112----121211-1-------13112111-12123121-1111122131122212412---2345------11-1-212221211122-22221212122112222211-11111-2121212323211112122123221----------------2---------13531---11------1112322332222341343333433322241121111111111-1132222232222442212211311111-1-221122----------1------------------1--------1-------3322 ----11--2111331111113211-111111112111111111111111111111111111121111111111111111111111111112111111111111111-2111233232113223142162HPA-656111111274-1221224622221331-111172251113123-----262113111-132231 * c.44.1.1 Low-molecular-weight phosphotyrosine protein phosphatases
[ 665] ----112---------11--1----11-1-2-111--------------1---1-1-----------3 2131311111111111122-211122222221111123221222332-2211122112--113332112112222222111121121122222211---11111-11111111111111111121111111131111122---11121133212112111111111111111-121221-13---1111-21211111-11-111--122111111--22211111111131222222222222221222221111-11111111111111111111111112221111111111111111111111111111111111111-23231112213312-2113111222-1311114232321212111--1---4222211111213222322222211111111112-111112112221322111333122222111211111111222222222-11132211----------11111111111112131114211222221111111333311113333221121112121112111111111221211112111111111111112-2213431344332-21321312322323231211132213211111111121111221112122221232332111221222212331--121111-11111112111111111111-111111111111111111111111121111111111111111111111111111111111111211-11111111111112111111111111111111111121--1111221212123121222211111111123211111112212222122221111111112122223311111111--1-------------------------1321111111-211 3222332-6322423222222222222222222222232213222222222222222222222222221222222332232222223334532333222223265523E258B4655443454385454LT4-6492532744322345142465433548822222422279324554e4345477CE2943545648 * c.68.1.5 UDP-glucose pyrophosphorylase
[ 666] 22225233333333232212111374455233222223333332322222232211122222331-11 -25361--------22211-11--471111146121348413246311112-4451-2--238261654411---22211335211111111-322----1111311-2--------------------------33311---2111-----11-----------1111-------------3441112-1-12232323222234324411113221113---------431111111111111111---13-1----1-------11------------1---2--1111111111111111111111112---------12213222121231316--111-2212-1--311111431323222112-2113332-------647---1---133233333343-53533454431-54453357338A52-1134722225643333333332231-12------------------------------115311212-4335345222244754334345486B85-122323211524244-41111222---------1321123112232322231221112111334366231111111111111111111111111222--2112131-------13----111---1---1111------11225-22222222222-222222223222222222-343-1--1----------------2------21-122222222222---211111111111514---------------2223224-3163555545754544635441---------2357-----2-11143445444441111--13111111------------------1-----------------34545222221111 ----221-311-1112255444256582212211111111111111224597E824332222121-11111122111-111111111123A321422122421111-1433131112111211121232791132211111211111112113211311---1312111141231122182113232343-11-B5561 * c.1.9.9 SAH/MTA deaminase-like
[ 667] ------------------------22222222-------------2---------2-222------22 2222222222222222222-222222222222222222222222222222222222222222222222222----2-----22222222222-222---222222222222222222222222222222222222222-222222224222222222222222222222222222222222222222---2222222222222222222222222222222222------2222222222222222222222--2----2---2-22----222-222222-------22222222222-----------------------22-22222222222222222222-222--2222222222422222-2-22222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222---------------222222222222222444444222222222222222422222222222222222222222222222422222222222222222222222222222222222222222222222222222222222222222222222224442222224444444444444444444442-2222222-22222222222222222222-2222222222222222222222224422222222222222222222222222222222222222222222222222224242222222222222222222222222222222222222244442222222222222244442222244444222222222222222222222222------------------------------------22-222-2222222 ------2-----222222222222222222222222-22212222222222222-222-21222222222242222222222222222224222222222222222-22------------------------------------------------------------------222382222222-62222222222 * b.43.4.3 Riboflavin synthase
[ 668] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------6PIR*mWCBDBDEAccB*C***-*Q*DACBHBEPHBEE6Cc4BfCHDAE265------------------------------------- * g.27.1.1 Fibronectin type I module
[ 669] 22----6343334447-2313---52261254-----------------------------1----11 1372112111111132211-151121111112333425342342112121111111111122323222223------------33323---------111433252332--------------22-11-1--1--22222---25332211111222122232312534211111111211212122---23222222222222222223332222227744221111114321112111111111111112-------1------------------------------------------------------------------------------------------2----11---------------3-323351111114765643333443344344344413564383467414443857665A93322244555553372222222223322541222222222211222222221222-212211243-155385333343455544477988574566889227674345533546263554434222222223557433-1---11-1-111-525-2112-566634-13221111111111111111131-332222143233342333333434444423543411-53-511111111111111111111111-1111111111111111111111111111111111111111111111----111111111111111112311111232233411---111---------11111111123377774656444446222-1111111111114111114332233222222221111222-442211----------------------------------------------57-1 -2------1-----1--2---------112-12111-------122-2------1114----6-311---1-1---611---------1----1--111-1----3------11111-----1-1--1-1C--11-----1--21--------1-1--1---12-112--*-15-1-1-------1--5--1--1---- * f.24.1.1 Cytochrome c oxidase subunit I-like
[ 670] ------2222221211-1-2----1--1------------------------1--------------1 112-3--2223---4LD22-2Q--9F212225NMPR64MI-74H--------3131----214-1252331-----------1---------------------1------------------------1-----22221----39585663-333212121251666A51-1111111111--------1----------1---1-------------------------1--------------------------------------------------------------------------------------------1-----------------------------------------------1-27332------2528---2--4-11111111111-65344753-35-311232334435122121552--14255555555523343-1---------------------1--------1-S*2-5C767B9AADD98BB9CCBBCCEE38H9T4F8512534483316782EA17-121211-------1111651--------------1111221---1--64---------------------------11----2-1-41------1-1----1-1--------2-----------1--1222-2---12-12222--2222-2222222334--12-----------------12111112---1-111111111---------111114155---------------8776736-1-2-665637341565514221--1-11-------------------33333112-------1----11------------------------------------1--1-2-2112--- ------1-----112212133327465332312----------221----36B7121------1-----1--1-1------11111-----111----------1--3K4A1232211-1111-11-1-421-212---11-12-111111--1112-433223121111-113--9B5l4659F98BE18511---16 * b.33.1.2 Ring hydroxylating alpha subunit ISP domain
[ 671] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----8B5-----223--------------------------------------------------------------------------------------------8--aeaWQXdRJMLPNPbMKoN**W-pRoOONOQJOQYMNPQQaONqNhSOMEM7DIDLIDDHILXCC-----------------------1 * a.24.9.1 alpha-catenin/vinculin
[ 672] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3244DCA-B43-467667767777757776778777674767776766777776667777776677683586776786787657757654656446222323388819L9NDHBDBHBB8EBEBUM9RCc*J4UFZ8BDAKAEIAADBABGAANAJFEEDBEEHDB8H8DA5AEC5786B746B7DCGK7J67778775 * d.15.1.2 UBX domain
[ 673] --1--11111111111-1111211111--211111--1------211111321-22222311332--- 1352211111112-11111-13113311111155551333321111111111121221--113422333211111111223521111122322211----1-1122112---------------585666466251-111333-11-1-222-1---------1-----1-1-----1----22111111122222221131212112322222112232121211111123111111111111111111114---22-------2222-1--1-212--------11----------------------------------123376666666778123312243222-16262DB57621238233211-2111115-----243341115322522222222222-11111111321-2112222222221211222222223224444444422212624--------11-------------------111412111114334342333244343333234433434-1222312112217321163-21241111111---934-CK4726646798514362324643253122A1--2-2222211-11111112313211533121311231321212611112122195---2444------314231-4444444444-444443544444444344221121113222222222222222212323332--111111121111-------------312111113-21----211111111111112122222332122222111---------13558222224624411111111111111335211------------41--------------------------323222122112-- 11--111-1--111111111111111111-11111111111111111111111111111111111111--1-11111-1111111111111111111111111212-221411111-1111-111212-5D1-323111--111-11111111122111137252236234223--111G---1142241131111111 * a.1.2.2 Dihydropyrimidine dehydrogenase, N-terminal domain
[ 674] 331311-11-----13-312211--11------11221111111-----111132212111---2--1 111-1-1122211-1-------111----------------111-21-1---1--1------11---1-11-------3-141312211111-211--------322-21111111111111131111121211145521---711--5--2--1111--1-1--1---111--11211--1333341121111111111111111111-11111111-1211-11111113111111111111111122111-1--------11----------11111111111111111111111111111111111111222222221111-2-------21211--21114-2--122-----11--12-2211-1-1131-14211-1-21-1-1---1-111132-11112---1--2--13--122111111122--22-3123121221-------------113-------------1---------------111211-----1222211111111111111111111111--1112132211111---1----312211113--11114-123-21-1-111-212212141222264121--1----------------1121-11233334312433444444434444444433--2-3131--11122312222222222222-2222222222222222222222111112222222222222222222222211-334334434444--121111122222334411111121-1111112223222221233433344444443455622222222233333223223334322232332222222--21333344--------1-1-------------------------2212211112243- 7712637-B21-432221121231212342222222--11213433133322332124133223121-2322-2211---13211112154424331225415332-6i5F1673254374454632449B4-5485224725425332263163131322433--122221-2457BGV7A6735898-55MC7677C * c.66.1.51 hypothetical RNA methyltransferase
[ 675] -------------------------------------------------------------------- 1------------------------------------1-----------11------------------------111------------1--------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11----------1-----------------------------------1--------1--------------11111111---22-------------------------------------1-----111111-111-----1111-11------------------------------1---------------------------3---------------------------------------------------------------------------------------11112112223222222-222222122222222222222211---111111-11111111111122222--211111111111--1------1111----1----1----------1111111---------------------1112122-21---------------1131311111-------------------------------1-------------------------------- 2333554-I844228BBDDABCDHEFC6666667778988878777CB89DCCF99C77777434163251123366346144435445ALAB698665555952518D7FAC9B8E868BA89PF8K9a*A2KCR9AA99788788985B86IAA78868BDD8AKI7CcOQB62472B222225344D3354EFHD3 * c.60.1.2 Histidine acid phosphatase
[ 676] -------111111111--11------------------------1----------------211---- 32F-61-1----------------1------1--------1---1-11----111--1-----11--433---------111111111BB8938451--39655F5754222222222222223333443234434557711121634633333332222223337444322222222222233311111112222221121211111112222121121211111111132211111111111111111111---11--1-122--11--1------1111------------------------------2---------242111111111212223322222544721121222223241111A2211E13133411111112221122211111111111112-11211112111-3111122222321112411111111112222222222232122------------1121111111111----1312211111112232111111111111111122111111111111111511121112111111111111111112242312121112111122212232133432721111111111111111111111111111211323222415444443444446445456--21231------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--26111111111124221111-111111111122232222222322222222222222222---------11111222222212245242653333444111144222211111111611------523--------4-------36214121111512 -----------2dX32573-1215-51111111322211111111133221122333--222---------------------------12-522--------111-1B4122424444-6424444454C4-444-44544444243444--445444----1---------2-4564X4443553247446651114 * c.14.1.2 Tail specific protease, catalytic domain
[ 677] 11111111111112211---11-193322441523--22--112111111332-11-111-2321--- 32-111-22222-232133-39118133333273352333131322-1214-226-11--1122324353-32222111253-112222211-2---11-21214411211111111111111-1--2-1--1-----1----11-222111--22--2---2231542----1-----1---11----1211222222221222222--1111222---1-1132222122122131111222212131111231331-222221133222---2332112------2223222222211221111111112111-21111-4313111222122213221121111431-2--422---111-31212424-12221-----241222-1221-31111111-113-231124-1221-2--1113311232332111121221123333333332111213------------------------------1221--111-333423333333313333333341123---22213111-1--11221-112431111------2221-21---1-31321-2131111--12-112-131221334422232212222-3-1-22222---11111-------1--121-1-21-----1-2------111-2-21111111111-11111111111111111122-1-----1111111111111111-1-----11--11111111111---------23332-1--111-1----------111111313-2133433434-2343132311-1-11-112111-----1-11111-1-11-------111-222211--------2-2---1------------------1111121--2---3233 3411522-81224423243232232321123-313132524221333334757934433323341111-211332121342321223-23622-25-1-1--2-362-9733-4-2B47-3415513749Z-243A3357222433645144267151342325121---2442-2265j54222952A5693269676 * c.108.1.4 Phosphoserine phosphatase
[ 678] 11111111111111211111111222222222222222222222224222222211111111111211 1111111122111111111-1111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111112111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1-1111-11111111111111111111-11111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 54334433A33355333433333333333332333343434433334333333333333333343333-43333343-533333333333633433333333333734837354555745733444669Fd3-5445385363434499738757534348G8345833-733954553g33444O57A35C3353435 * e.29.1.1 RNA-polymerase beta
[ 679] -----------------1-----122221321------1111---1--------1-1----------- 21527-1-----1111111-13--13111111322223341132--------13212---211-2243422----122345531-11111---------1413331312---------------222223222131111111-3121231112223-----111233241------------43311221314666665552644554755554474342537244444448222222222222221322342152--24--1441121211221122-------1-111111111111-------------133111333-12146444556515122112112235111113144322112321112-3-4156333-1111541-22211211222222222225-3432433234615AA35556665534131447454542533333333344348451111122211112122-2211122-----113532322254345453555533345555455443365122232254333342234232224122222222243322121-326363446-6852656423363423142222111111-1-------2112133333223131232222222232222222222--15464------32232333333333333-3333333343323333332454223422322222222222222432222321-222222222222---22222222225252211111111111211133333221321333332212112121211211111111322221111122222221222211111111132--1111--------2--------------------1------12211212221311 -------------1-----------------------------------------------------------------------------------------------------------------------------------------------------2------2--------------1----2---1---- * a.4.5.55 Transcriptional regulator Rrf2
[ 680] ---2--2222222222-2222223222222223333334333333333433333-2122212----22 2222222222222222222-22222222222222222222222222232222222222--222222222222222222--22222222222222------222222223---------------222222223222222233322222322222223223222222222223222334233222222222222222222222222222222222222222222222222222-22222222222222222-2----22-2---22--22----2-222-------222------------------------2----2----22-2222222-2-2223222---3-2--2232222222222222222--22232222-----232222322222222222222222233333333222-2222222322222322222222222332222222222223222-----------------------------2322222222222222222222222322222222322222222233222232234233233322222222222222214332222222222-2223223222222223342222333333-2-------22222222222222222222222222222222222222--322222222222222222222222222-2222222222222222222222223322222222222222222222222222-22222221222222-2-----333332322222222-2221---2222222222222323222222222222222--------222322222222224222222222222222232223322--------------------------------------2--2-2222222 ------2-----2222222222223222222222222222222222222222221222222222222222222222212222222122224222222222231222-22----------------------------------------------------------------3-2223M2222232352242222222 * c.1.2.1 Histidine biosynthesis enzymes
[ 681] -----11---------1-1113311-------------------------233--------------- 234-2-11121-1-123--------2------------11-1-2-2------111-11----1----1-----------23212211------1------2-----------------------21-22212222---11------114111--11------1213222---------------------1----------------------------------------1----------------------------------------------------------------------------------------------------------------------3--3166--13--31--------2-3225-----57B8B6-37663833333333333-4574556B241-222224242332661214286577324111111116551263511-1111111----11-11---11-111111452-322268777668555455AC6666377BC445644566543345959413433132641222212---37821-13121213111232332241134342-415233322222213111111136212564424337623378A9926ABBA79A88797---1631------53549517777777677-777876775676677777535333324878788888886867767666665--444444444444---3-----222243133111112111111--22222211213646676555634545644422121332223336444445343233333333331111--3-----------------------------------------------------121- ------1-----------------------------------------------------------------------------------------------------2-------------------------------------------------1----1---------1--------------1----11-1-- * f.21.1.1 Formate dehydrogenase N, cytochrome (gamma) subunit
[ 682] ---111-111111111-11--1-17333--33--1---11221---3---52212221212-112--1 14619---11----52211-12---811111-2323469916142222---13341-1--22411498A31-----------7-----3321--------2---4-2-1--------------------------21111---213123-----22-----1---23461-1-1-----1--122-------2665664461466466342223545-1-5111222222451111111111111112111331--11-1---42--111----1-------------------------------------2----------1221444445414118331221321-11-22-46-2--1111----1---322225-----12D551113111211111111113-227325256A2-E44288786567432221474143568--------2--1-2-3------------------------------1343-16321BDDDBB45553AA94777725E983684--654-2-----51721311---1---------11-1-2412111--------22111112-146138-311------------------122--22322-323-1--1111121-11111--1132---1221------4621-715543544445-555443444453444544165732-416555656666666656611233231-1---------------11111-21-1-581---------------3232322-1-1277774654376632735---------1-11-21211111----222222221111--11221111--------1-1-------------------------222221311114-- --1---------11111-11112223211112111111-1111-1-1111243211321333111-------111------111111111-11-13211-111----1411111211112-12-22-1-141-112--1-2-11-12---12-1-4-21---111-----------12-V11-222134-1-1-----2 * b.82.1.11 YlbA-like
[ 683] ------------------------1------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 1111--I-1--------------------------------------------------------------------------------------------------2--*gVakVFDCFDGHENS9XF**M-aFS1DCBNFGEGCGDBAJC8WCBGKIZrdWsy--1---12uX-bcG*1116-253A-6E------- * b.12.1.3 Alpha-toxin, C-terminal domain
[ 684] ---------------------------------------------1---1221-----------1-12 98*1S-111151---------2---------------2---3--1---1---2-1---BB----2--2-----------------1--222-----------48Z141A---------------2-531-253C-122A2---3-24---1-----1--------1381B------------21111------------2-------------------------------DE222222-2222222-2I---4------------1--------------------------------------------------------1-------------2-----------16--B----1-12------11----8---1----------4-----4-----------------v----------73A-547--------1--1------------------N6------------------------------1---1--83--------1-------------------12---88N1---5--2811-I----3-----------21-27-2-1---------a7J-6CD-212-2G-3C2-------------------1---------21l4-1-113FF-1-1F11326223HB--------------228------------------------------------3F--------------------------------------------3---------1-T-3------------------------1-X-----4--------111----------1--2-----166----39599455------r-1122DA------------------------------------11---------Q-- ----5-3------11--3133443444---------------------4454441144-333334333333343433333344434---562-3334437-45----412PBF75564343354A5183EQ6-6274542534533434443183443521-35352743233JB---12111----3-3---2----- * b.1.6.2 Dystroglycan, N-terminal domain
[ 685] ----------------------------------1---------------1--------1-------- -11-11-1111---1--11-13--1-11111-3---2-11-211212-----3-1-----342-122235-2111111----------22331411----211321234---------------21121111112-1111---411-21-11--11------2---22--------------1----------222222222222222------232-----12------1-1111--11111111-111------11---------11------111---1--1-------1--------11----------11---111--1---11-1111211-1---11-------------11------------21-32112--------1----11-2-11-1111---1-112-121-22-1---3221222211-12-2111111222-------------111------------------------------1-3--12222222212-1111221211111122-32321111212232121231222241121-------11221122-1--1--------111-----11-2175-111-------------------------45-111212323111131313122122143---4---------2212-1-1111111111-111111111111111111111111-1-1111111111111111--111111-----------------1111111111--4------21---------221121-1221-22221232122211111111111111-232611111663565556766222-1-1------2244------------------------111--------------------41- 3311539-C56-126435564445456444334444342433343423347595445465453344441433433653553565553345763246322223367719OBF5695A76645768CC575Cc929893555967A658565857759986697AA954A34412872849h85543866635634DEEF3 * d.151.1.3 Sphingomyelin phosphodiesterase-like
[ 686] -------------------------------------------------2------------------ ----------------------------------------------------------------------------------------111--------------1-------------------------------------------------------------------------------1------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------1---------------1---------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------1----------------------------------------------------------------------------- ------7-----11211112221222311-211111111111111111112232112111111-----------------------1111-111112-2112132313--XRbTcPVQOOGORMmfKmO**d5fN*MQPMVMNVKFNPMITMIWMOPKL6FWKBID7H87e55DF----4---1---2-1--------2 * d.92.1.10 TNF-alpha converting enzyme, TACE, catalytic domain
[ 687] ------------------------1--1----1----------------------------------- 3-11C22111121173644-4422D44444436343A8GE-C962----2---111----A9-1C2EH8G2-------------1---11----------2---5---1----------------1--1-------------1A-1342333--11-----11-1473F4------------1--11--1--8111115131231332-13345214---11111--1113---------------------------------1--1---------------1--12--1---1---1-------------1------------121111311-1-2-44-1----111-----332--------------1-3---------13126---16---------------2141211114--511511-1-11-14-1---2-1---11---------1---1-1--------------------------------1-------334248979941123HHGH4E4214121--117--2--2--143-------5----------2---1------22--------1------11-1C7------1-----------------------1--23-----1----3--------------------------6162-111114144311-112111313313311111112331CB2111111111111111131111111--243444222242---1-2---322212A-3111------------22232-1---458A799A76122221D7C------------12-----2--111121212111------------------------------------------------------------12-- --11-12-3-----366739443DADC54444489925652553326567955355B87433111--1-11-21211-1-1111111-11546213111-114232--Y5B4642233221231441A2DQ6-74632126143-14352511535324241135-94469432526A37465A8111A66-4225227 * c.69.1.22 Thioesterase domain of polypeptide, polyketide and fatty acid synthases
[ 688] ---------------------------------------------------1-------1-------- -12-2------------------------------------3-1---1------------1---1-311---------------1---11-------------1511--------------------111--2--1---21112-727-3341-11------1--39789---------------------------------1--------------1------------------------------------------------------------------------1-------------------------------1---1111111-1--------------------1----------------1----------15IIC25153778------------11911B11-8--1--141-572---4-----23-22-1--------------4-1---------------------------------1--1--------------1111-------21------1--------21-----C------------------3--152----15------231---1211224-1--------1------------------------1------1------1------------1-----------------------------------------------------------------------------------------------------------2-----------------111-11----------1111111111211------------1-----------11111121111111--2-221111-------------------------------------------------- 1---11--1----12111-2222333211111121211----111111232223-1212221-1111111121121111111111111113114291--1--1422-541*FRGFUSDDJFFFAHLEaB**Y-eLQEGCEMCEFECEGEGICCeFHEBDKOJEeIM58HA827E7-1--1--1-11--21--31----- * c.17.1.1 Caspase catalytic domain
[ 689] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2323YZ2-832-435212212222222333333333222222233311111111111111111111-1111111111-1111111122221213222222242594-2D4zLMDHJJCCBBCVCXJBPAY*N1KDPABBBEABED8CEBBCA7M8EACCHLKBFFD8DCJ8F*S71836D33257FxWw2*D-212223 * b.8.1.1 MATH domain
[ 690] 11253513211111113-21112-2112111111-3322222234232-212234344432-2-1131 322-52-222222253322-23--33222223243446762223---12---222222--225-4235622--------1--1--2--233423-----2212322224---------------------12--2-1111---1-432222211111111111111322212111122111111111---11111112122132212211221211211121-111111122---------------111112------------11--------112---------------------1----111-11-1----------11-21111-1-112122111---1-2--1121222-----------1121--22222-----222332222322322222222223133224333522-2335223222442322211211113112222222222242322------------------------------42522-221442232233333332233343535333342253326432345433232-22222--42222222322-41--112111111-3332224212-2221--3----111111---------22-11532433522-23222222232322222332322--2421---22252322523455345533-4345534345443323333334422233333333333353433232322322-21112331322322-2-1--1----2153222-2-2---------32522221112233342334222322343-----1----42432222222225--322222223222--1-222222---------------------------------------------12331 11--212-31111122222222222222232222222333332333224233231223323222223222322222222222222222253222223332222224-23-211112-111-1-132122592-2321112212111111111211-11332222111412-1232322181113332242432322222 * c.26.2.2 PAPS reductase-like
[ 691] -------------------------------------------------------------------- --------------------------------------------------------------------------------1---------8-------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----A63----------------------------------------------------------------------------------------------------142PqhcmcZOJGNLSSfaJcK**TIcYt7JIGYOOXKAPNGEkC7*TPLNQ5M45aJ82G79b8949-42---1-----------2-2121 * b.1.18.18 Other IPT/TIG domains
[ 692] 331-113566666543--111---2332--22----------------------11111122111--- 1115121222213111111-1111111111111111122211112221222133333311112111312211111111---14331112221-21111111111111212222222222222221111111114122212---23222222222222222222222222222222222222211111111223333333333333333333333333322333333333333344444444444443333433-4-22-3---332222211112111333311111111111-1111133333333333331221112221121--2222222121-322----11--13----11-1-1111222212-1212111111111111111111111111111111112-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111222221111111111111111111111112222111111212211121111111111111111111111212-2-3111211111-222122212111112-11---------------------111443311113211211111111111111111121-1111311111122212212222222222-223222222222222222233312112222222222222222222221112112222222222221111111111111111121112121111111111111111122112222222212222122222222222211113222222222211111111111111111-222222--------2-211111-3-22111222121121---11111111111222 33--331-722-2221221222222222222112222222222222222222212232222222222222222222222222222221223222222222232222-273312232-222-12122121955-222111222231-21-122122121333322222322911324333T3332333652453432222 * d.104.1.3 LplA-like
[ 693] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 22--33L-94224333353444444434445453343444424444444443442444344444444424444434433334444433348535346454344B6E1772UVeTRMNGEEDEHHggEUC**S7aJn9FFDUCGIF8GHFCLBASHGFGI6B7ELIA8S79Q76G42222B11-223222421235BBA8 * b.34.10.1 Cap-Gly domain
[ 694] 22----1666666565-2------21111121-----------1---------1111----------- 14A-A--1223---2TH44-4D11LJ44444CGCHC44BE-L3e411-----3341-1--322-3178731----1---1118-----1111--------1-152-2-7----------------1-1----1--12233111-6-112--1-------1---1--1-3-------------2-------1-2------1--1-------111--11--11---1111--43-111211-11111113--2--111111---132--22-----1---1112----11------------------------1---------11-1---------1-1-22------3---2-1-12-22-111---11---5139111------1HCC--1423531111111-1-1---5--8-7654-6552325834446253-334222211111111111311--2--------------------------------18J4-1C85658AB973333277CD444416C3I7C62--221411--86C4F8--1---1----------12-31-3241122221221-464142211----4723--21-22112--------------1-----1--1251-1-----------------1------2-------------------------------1----2-----1111---------------------2----------11111-11111---1111111222-1-34---1-2---------11111-----21222213411234411221111111111----------------22222332--------11--1-------------------------------------------1----41- ----223-----12-77B59686FHB72212223323333433433774789DG33655545111--------11---------1----6C4725311112-222--1615221121321111111231331-21221311111111211111211211231161-----1322----1A111-15123A222221117 * c.1.9.15 PP1699/LP2961-like
[ 695] ------------------------22222222111---2222222222-2222-------------22 2323222222222222222-22222222222222223222222223222222222222222232222222322222222222322222222222223--222222124222222222222222223332223243222222222322222222222222222222322222222222222222221122222233333333332333223333233233332224444443222222222222222222222322222222222222222222222222221222222222222222221111111111111222222222233334333333323223333222222132323344322333333333222424322323222222222222222222222222222-2222222222222222222222222222222322221222222222212222222222---------223322222222222222222222222222212222222222222221222222222222222222222222222222222222222222222222322222222222222222222222223222222212222222222222222222222222222222222322222222222222222--22222------22222222222222222-2222222222222222222222222222222222222222222222222222-222222222222--222222222222222222222222211222222222222222222222222222222222222222222222221222222222222222222222222-22222222---11111222222-2-21212211--22212211122222222223322 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3----1------------------1---- * a.2.9.1 C-terminal UvrC-binding domain of UvrB
[ 696] -------------------------------------------------------------------- 2223423323333333333-33223333333333334344233334443443333333113433444333333333322332211111333322222-133333222221111111111111122222222222233333---4232222222222222222222222222222111222222222222122222222222222222222222222222222222222222222222222222222222222222322322222233222222222222222222222222222222122222222222222222222222222222222222222222222222222222232233222222222222122122333333223111111111111133332333333-22222222332132233333333322231111111111111111111111111311111111111111111111111111111112212222222222222222222222222222222222222222222222222222222322221212222222222211211111111111111111111111111211111111111111111111121113111112221112221111111111111111111-11111------22222222222222121-222222222222222222222222222222222222222222222222222212222222222221111111111111211112222222122222222222222222131111111111111211111111111111111222222222222222222221111111-3322111-1-1---21221212-112121-22222-1221111111111111-3-3 11--22--422-1111-111111111111-11111111-111111111111111-11-111-111111-11111111-1111-111-11--------------222--3-312223121121212212-2D2-21311212122212211121212111211-1-31111-1112122262212111131221111112 * d.79.3.3 RNA 2'-O ribose methyltransferase substrate binding domain
[ 697] 111-111111111111111111--11111111---11111111-1-11-1111-11111111111--- 1211121222222111111-12111211111122221142111111111111111321111111111222111111111-1-1-11-11111-1--2--1111111111111111111111111---------1-11111---11342322322111111111223222111111111112211111111111222222221222222111111222122211111111112111111111111111111111111111111111111111111111111111111111111211111111111111111111121111111111231111111313111113332111111121111211111111111111111111-11-1311221122222211111111111-2231352211112114111111112111-11121221111111111111111221------------------------------11111111112111111111111112222121113233112221111111112111311111-11111111221121111111111111111111112111111221211111111111-----------111333331311111212111111111111111111-1211211111122222222222222222-22222222222222222222222222322222222222222222222222221222222222222111111111111111111111111111111111----------6122222222222333111111111111122223333323233111111111111111121223322111111111-1111-1-1111111111111111111-2111111111111 2211211-921243311111111111111111111111111111111111111111111211111111112111122-22111111111121111121111113351273447345523232223B183Ed5-53B131152223-2312211312122122322245236361147C8*22255JAKL1E775958H6 * c.1.12.1 Pyruvate kinase
[ 698] 223-1-788998A989--21111-2---1--------------------------------1------ 13824---------1--11-12--5711111433331369231311---11-2121----1-A-34B555--------1---4---1-------------1-256-5----------------------------44433----A-1-111---------------1-2--------------23-------1---------------12---1----21-----------1--------------------1----------------------------------------------------------------------53-24444344434-5------31-21-112-312332-2-3-------4--4332-----24HIJ413586B61111-11-111-A9F88EBE783-62241194317C8523-881444466844444444A3331521------------------------------2351-56435ABBBBA22221BBCC22221285GDBE4-2665434118261B2131-1111-----------2211-3-4111121111--1113111311-133-4-------------------------222--4112-4-112222232111111--1-1----1---------1--2--3332322232-3333212323323332331------------------------51--1112-----------------------------321---------------1111111-214166663284454553423---------1---3----------1123233----------2--------------11---------------------------2222-----12-- ----111-----11-21222121121222232211111111112221211122211111111-----------1-----------------11-------1-1----243A23234A22222525D252282-32422224226222222C2292624526O2663A69D8E354-13-9---2344842761121112 * d.41.1.1 CO dehydrogenase molybdoprotein N-domain-like
[ 699] 1111-111----------1--11------------------------------1------------1- 3331222222212132222-22332222222222222222223222222222222222112222222222221111112112211111222222222--222222222211111111111111122322222222122222222222222222222111111321222221111111111111321122122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222223222222222222222222222222222232222222222222222222222222222222121123222212212222222222222222222222222-22222212122122222222222222113211232223222222222122112212211111111212222223223223111111211122222222222222222222222222222222222222222222222222222222222222232222222222323231322221222222222332322221212122221122222222211111222222222222222222222222222222222-2222222222222222222222222222-22222222222222222222222222222222222222222222222222221222222222222222222222222222222323222222222222222222222222222222222222222221111111112222222222222222222222222222222222211221111111123121211-121122211111221122122222222221222 -11-----31-1---121111111111111111-2111212111-111111111-22222-2211222111111221121211111111132221212222211-2----1-----1-1-11-1--2-113-----111-21-----11--11---1------2--1----21---------------21----11-1- * c.55.1.9 YeaZ-like
[ 700] -----------------------1111111111111111111111111111112-------111--11 111-1-11111-1111111-11111111111111111111-11111---11----111--111-11111111111111---11-1--------------------------------------------------111-1---2-111-1112211111111-11111111111111-1111--------11-111111-1111111111---111111111--111111-1---------------------1-1--111-111-----1----1-1111111--11111---11-1-1111111111111---------111---111111111111111---111--1---1--111--1----11-----1122222222122222222222222222221222-222222222221211111211211222221111111111333333332332123211111-1111--22222232222221111-212221111111111111111111111111111111111111111222221122111111122111111111123232222112121222111111112111111112------------1------------112222222222222222222222222222221-11221111--122222222222222222-2222222222222222222222222222222222222222222222222222-2222222222221112111112222223222222222222212221111111111222222222222222222211111111112222111112222222222222222222111211----1111111121---------1---------1------1--1---------- 34134561A553244442332334333333433432354445533224444343345434343443333333434333333333444433734234323333344424648584564524434377484Fb816792333645823333552463735444256553657C47662654Q3424443343475555545 * c.66.1.2 RNA methyltransferase FtsJ
[ 701] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122CC4-1--14446666555555555554445455655655555665577777667666644444444674347758844444567658565574444555C98-A-4DORIVKIHGECDCFdTFUK**Q5UJZFEGDKEDE8ACEGCFEEYLDDDA5BG776C884485A764424Z4444DB68B6F5--2122- * d.338.1.1 Oxysterol-binding protein
[ 702] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------1-1---------------5-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------45--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------*-------1-212533433231113222122212-2221121-1112-11322411265434-48944657277477744444---2----------565-F9-9TOGUTFFDEFFGDOSCHCj*R-RFeADDEDDEGB8EECCMBBaGPBC76ASC3B96K65M**23-23-1--2-1--2-2--------- * c.10.2.5 L domain
[ 703] -------------------------------------------------------------------- 458------------1111-1---1-11111--1-1----1111--1---------------1-111111---------111132322223222222--2222222242111111111111111232222223321331111132223-22---11--1-------3211-1-----1----33333112111333334332333443-222214321--2321------3411111111111111111111111-22-111122112211111-121111111111111111111111222222222222211111111113522222222222224422222212322-1311--111222321133-12242433423333443533344634433333332324-2232332353322222333332223334443433332333333333332233333222111112233223322122222211121224223333564455453333334533333354545345443564333433433346344455333333333455446442223333334376745884488A855333333433333333333333323335232233332222222222223222222222231-2322321-22222322222222221222-22222222222222222222223222222222222222222222222222222222222222222112322222222243432222222222222222222222222234334332422333332222222222222222222222222223332222222222212342211221111111111--------------------------32222222223132 --------------------------------------------------------------------------------------------------------------------------------------------------------------1----2------------------------2-----1---- * a.223.1.2 Porin chaperone SurA, peptide-binding domain
[ 704] 22222222222222222222222222222222222222222222222222222222222222222222 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 44223332E552333333343333233333333333233323333333333333333333332233331334233243223333335553533333433332387B237463632353375364BJ4D24M6-5465233933552345132642234448333432343444334444a54444G89C3854434334 * c.12.1.1 Ribosomal proteins L15p and L18e
[ 705] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------WpoklndMQLORbSfcOjPz*i-fYrIOPObOYhYEYZSKWJIfQeTRgALL8EA93H65D5575------------------------ * g.17.1.2 Transforming growth factor (TGF)-beta
[ 706] 114-3--1--11-2-1-------321113122-2-151--22164235----2-1221---1492-K2 1-11222111-2-1-1-----------------1-121--3-23--1--1211311-111--22----22-----3----3-3--13453-2-5-1---4-12-1-1------------------55566--86-B99NC-135-56C523H-1----1---2-4-6548---------1--1--1131432-------4---1-1-111-------111--1-3--1--231------------------22-211--111---112-1--1---1--11--4-2111111222111212--11-11411-12211----1-21-1-----11-2-3122--1--171-33168-366A8122844-2222-61111113114121324442211211111111112-1322353152511121252124323622141813553122222222235522352-------------1-----------2-24114421-1-132233329222254134533242721325--235244331-21163523-121-341-3121222---451---412-242-21--1-5-132614542--1-3-3-14-D49BBCB781-1--21-2--2-1-2-2-2---2---1--1---3-1--381-1------1-2--121332141481-611414313352111111121--22462212222333323225-35-2112--111111111-----11------1--8-2--132121-32143-11-2---1----2311131--1----2---1-----1-----21111111111114-332113335486--B2223333--------4-2-2-2--2--22--3-2121-411112311411111512- 321-12--3-----4--1--------1------111----------1-1-1-1111---1--111111112111211111211112-11132-2222222121213-1333253221-1111113423-2B212323--22-223122122111112241213211122373-3-23226213121463-32--11--- * c.66.1.11 Type II DNA methylase
[ 707] --1-1--1------1---------1--1-11-------------------------1---1------- -11-1218332---25211-11--2211111111124223-26-1---211--1--1---26--432761-----12---22-------11-13------2111233-1--------------22-1231111-----1----2----1--111------1----1-2--1----1--------------1--44322112113211112241111312----122111-3-121111221211212-1---32-1211----11212--3-21-32111--------1--211-11-1--22---11-----11---21212-141121121123-14441---11--1-421--1332-1-1-1111----1-E7792KC2V324373113222322122232123-B9885E873722A5587995777435365317312232277777777332559C911111111112221331321212214-421--2--653431115214----121-11211248-2232--231--6219122511122-12152124413232512-53--11224-4432-333--4-3-1-2111---------------------1----3-1211211-111-2452211--13-221-----221-4------275B3225CB55756441C4555A5569F6724734836387ELJ5623234231443334421344315-444444434649--4------2-2---3131-1511251134-512-142522-141556A331416446-522----------12212744733431211-1--12154-3--51112233--------2----------------------------11----------1 -------------------------------------------------------1---------------------------------------------------------------------------------------6--------------1-----------------------------2---------- * a.35.1.2 Phage repressors
[ 708] 11121212222222222221123222222212221111222222112312222222222221111-11 1122212222221222233-3211223333322222222222222222211222322111332122323221111222112222222211111111----212122221---------------222222322222222222222223222122221111112221222211111111111122222221222333333333333333222222333322312222222123111111111111111211111111221212122222212121111111111111112222222222222222222222221111111111121332222222222223322221121122111332231222211121211111112-----2122211122222----------1-11211112131-11121111111122111--1212211122222222333123231111111111-------------------111112111113222221111133212222222322222114221111113121-11111112111111111-212213-111112211111222223221222233222223111111111111111123221221131111211111111111111211112111-12222------22111111222122211-11112221211221111111111111111111111111111111112222111111111111111--11222222222212111--1212-1---1122222222222211111111111111111122222222211111111111111121222222221111112-11111111111111111----1-111111111111111-11111122212222311 11--222-1--13221111111111111111111111111111111111-1111111111111111-1-1--11111111111111---21111111111111111-2216464493143233334443CU3-2253233225311223232142544325B33313B14313542222K2222223541432222224 * c.1.17.1 NadC C-terminal domain-like
[ 709] -------------------------------------------------------------------- -----22-224-2------------------------------------111-22--------3-----1-2---222----------------------------------------------------------------------------------------------------------------16C6969A68AD96666AODLLMG8866862847NPRTOQ942AAA8AA8AAAAAAA74445H6--FL--8-8IJ--DO-274433425879979967A88868A6A48666666666666669822-999B-5-BcCCCEAAEBA9-o--2222-2-2-8-3-----2--2---GFB--11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------21-----------------------------------------7584-734118488863-1444688642182444444787AB332747657787874846664314444--811111111111---------------------411-1111-111---------------------------------------233----------------------------2-----------------------------------3-------------------- -------------2------------------------------------------------------------------------------------------------------------------------------------------------------------2---------------------------- * a.142.1.1 PTS-regulatory domain, PRD
[ 710] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------*gcWORYPKQHPUOdWORM**Y1rT*IRNKZOQZU6SHMISJGnNiPUO8BF537GAHLGBCHn6------------------------ * g.28.1.1 Thyroglobulin type-1 domain
[ 711] 11-1--211111122122--1--1423343621-1---1811-6C3-3-4553--------322---1 3---I--2222---51122-25--4B2222244666A985-D9I46-1111-632--3--312-9-BFE9--111-11--251-1-1-1211-12-----C---i6D-2--------------1----2---3----------22511422---111--1--11-31221------------11122--121799999B5B36B988A4688888191-18374322222CI2111111211221113--1431512211211775523443231243---1----23------------111111111111-11---11111-1AH2223232151-722113231---11---341------1---2-322-18772-----55967--14222-----------5-452645383B3-D664975A9A3654742-351--1-2411111111-5341-22-----------------------------223272122125784A434444445144444383435A4--2271-211523231-5--1112----------211-133-3111-31111-211--11121---33113-11-2121-1-1--------2---221-12113-2---211112-----1----22-------------2138-5-1111111111-111111111111111111146485--11111--1---11111141111111--411111111111---------2232-2622---211-----1--18888813--1-144243334-2121-233-------------1111-11-1--33131321111111---211------------1-1----1------------------------------1121 --------21----------------------------------------------------------------------------------------------------------------------------------------------------2----1------3--------------1--1-----2---- * a.4.5.69 HxlR-like
[ 712] 222-2-2222222222--------2222--22---------------------122222222224--- 222242-----22222222-2222422222222222226422222222-22-4422222222222222222-----------22----2222-222----222222222--------------22222212222222222---2222222222222222222222222222222222222222222222222222222222222222222222222222222222222224-22222222222222232222-----------------------------------------------------------------------42--2222222-2--222----2---22----22-2-22222222-2--2-2222222222222222222222222222222222-2222232-422-222222222222222222222222222222222222222-222-----------------------------22222-222222222222222222222222222222222--22222222222224--22---2222-22222222222-2-2222222222-2222222-2222222---------------------------2222-2-2422222222222222222222222--22222------22222222222222222-22222222222222222222222222222222-2222222222222222222-222222222222---222222222222222----------------------2224244444442246442222222222222-2222-222222222222222222222222-2-222222--------2-2-------------------------22222222222222 ----222-522-22222222223222222222222222222222222222222222222222222-22-22222222-2222222222224222222222222222-2-25242221232322245243292-22212-2222222233322321422332D32232214423522222b2222274562422232222 * c.67.1.7 Glycine dehydrogenase subunits (GDC-P)
[ 713] -----------------2-------------------------1--22-------------------- 131-211111111111111-11112-11111111111111122221212111121111--11141113321-------2-1-21-11133451311---11122111222222222222222212221212222433344---222322222-111------121-1211------------11111222111111111111111111211111111111-111111111111111111111111111111111-2112-11111--11111---1111111111111111111111111111111111111113111111121113111111121222111333212221432233222211232212311112-----------1--1---------------------1--1--1111111111111111----------------------------212--------------------------------1----------------------------------------21-1111-21---31---1--------11111113331121121111133322232111112333--------------------11111--11111111312-------------------1--1-1211111111111111111111111-1111111111111111111222221111111111111111111211111111-11111111111111112222211111111-111111111111111--------------------------------------1111111111111111111111111111111211111112222222222211111---1111111111111111133333242221231 4544222-6111222222222224244222222222222222222232222222222222222444442464444442544444442222422222333322344422415GIFJB57684767685C7Q*8-ICA7457C88A13882265758B66426L83422623546223333P22243EDIH2B63211114 * c.89.1.1 Phosphofructokinase
[ 714] -------------------------------------------------------------------- -------------------------------------1----------------------------------------------------------------1------------------------------------------------------------------1-----------------------------------------------------1---2---1------------------1-1----------22------2---------1------------------1--1-------------------------------1----------------1------------------------------------1-----------------1--1--1---------------------------2-1--------------------------------------------------------2-1-------2----11---------3------------1--3--------------11-------------------------------------------------------------------------------------------------------------------------11-------------3----1------------------------------------------1-----------------------------------------------------------2--------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------*-------------------------------------------------------------------MWQ*DCBYb****-**3O6465I * d.10.1.2 GCC-box binding domain
[ 715] 11-11-1111111211---2---122212-11-----------11-111-----1111111---1--- ---1222222212121122-22--13222231333323331321242142222221141123232233222111111111111112-----1--1----------1121--------------------------22222---34311211---11---11111122211-1-----1----1111111-225223232222222222632224222233232222222232233333333333333222222221221222222222222223122222222222222222222322222222222222222323322222222-2-1-1--11-11--------1---2--1111-11--1111111-2-1-211111111112222111111111111111-111-11111311122111111131212211221331111132111111111222-2112----------111111111111111----1-1-----------------11---1------------1---------------1----2112-----------211--1----11--111---------------------11111111---------1112---11-11-----2111111111111111-112--1-1-1------11--1111111111111-11111111111111111111111----11111111111111112111--11--111-11111111-------------1-11------1--------------------11111-----------21---------1----------1-------------------12112222------------------------------------1321111111---- 11--313-72211154455455544544434444444444454322544445443444543435524325226452212236666643333243334443333666-4L47A9A8645443254874B4Ah6-95A25328447415222522B5775548F98533979879232472W2334336974545767454 * c.108.1.14 NagD-like
[ 716] 11111111122111111111111111111111111111212232121311541211111111111-12 1111211111122221122-2111122222211111211111111212111111111111221112512111111111111121111111111111-11112111112111111111111111111111111211122221111111121111111111111111111112121211121111111111211222222222123222323111232211122211111113233613111123331111421211111111111111111111111111111111111111422111111111111121111111111211114214111111121213113111221111111111311111111111111112111111111224222222222322222222222-22322222441132223333332222111111111111211111111111121211111111111111111112111111111112232211112222322222221111222222311111111111121111212121111111111121111111112111111111111111111111211111111221112111111212211122113111221111111111111111111111111111111-1111111111111112121111111111-111111111111111111111111112111111111111111121111111112222222222221112111111111111111111111111111111-1111111111111111111111111111111111111222111111211111112122111111111111111111111111111121221-111111111111211111111111111111112 54-1323-92212222132212222222222122122222122122232122222232122222222222222223213222232222215212323333212343133274333743344244444665K415463444434524343443354444311244532735242432223F3322435573432352224 * c.66.1.24 rRNA adenine dimethylase-like
[ 717] -------------------------------------------------------------------- ----1311224-5------------1-----------111-----1-11----12--------5111222-1---2113---1----------------------------------------------------------------------------------------------------1-----3-37666666565665655B8BBA9765334128A25562612499999999999999555789A--65-161AGE--6A32543232355554444445555545554544444344434444663316664---6HBBBCBBC7A7-F--266611-4-212-----1------211--15---244---------------------------------1-----------------------------------------------------------------------------------1--------222222222222222222222322--2-----1------------------5----------------------------------------------------------------------1--88B-------61111112-111111--111-------11-1119E962E5777889A988-7778989889798887887DECDC6664644454454444444976477772-A44334443444--1---------------111362-----2--5------------22222423-------------------56665555556744-----------------9------44244444--1----B-3172522222376222111-------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------2----------------------------------- * d.95.1.1 Glucose permease domain IIB
[ 718] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------LZaYZbgNJPLNTNulLjN**a-qayJRRLdLRTLGQLMGVOGiQVJRNDKJMDAA8I98EAFG7------------------------ * a.4.5.21 ets domain
[ 719] ---2--2222222222-2222222222222222222222222222222422222-2-222-2----22 2222222222222222222-22222222222222222222242222222222222222--222222222222222222--22222222222222------222222222---------------222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222-22222222222222222-2----22-2---22--22----2-222-------222------------------------2----2----22-2222222-2-2222222---2-2--2222222222222222222--22222222-----222222222222222222222222222222222222-2222222222222222222222222222222222222222222-----------------------------22222222222222222222222222222222222222222222222222222222222222222222222222222-2222222222222-2222222222222222222222222222-2-------22222222222222222222222222222222222222--222222222222222222222222222-2222222222222222222222222222222222222222222222222222-22222222222222-2-----222222222222222-2222---2222222222222222222222222222222--------222222222222222222222222222222222222222--------------------------------------2--2-2222222 ------2-----442-2222222242222222222222222222222222222222222222222222222222-2221-22222222224222222222222222-23-------------------------------------------------2----4-2-------1-2222Q2321222262624224222 * d.14.1.9 Imidazole glycerol phosphate dehydratase
[ 720] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2-35556-G81-687555577878779555435666544434444524556666575655557755433563655452444555475558C556554444597986-CY9GGHDEBAB9A99AAIG6E9V*F2FCJ98A7E8AFB8C896B95E9B89B84E7H6aIdjsT779D3FA5d45454MLPg4ZE4753553 * a.5.3.1 CRAL/TRIO N-terminal domain
[ 721] ---------------------------1---------------------------------------1 -23-5---------31133-33--333333323222515617353541---------1--31---21425------------------------------3-11338-8--------------1---------------------9-1533111--321------34232--1--124---32---------------1-1-----1-1----------------------A----------------------------------------------------------------------------------------------------------------------------------------------34--4-----2-434-1123111--------------4--6-3-46-5--2231433221111-351----625--------2221-1---------------------------1-2-12356-222134565756111133354334146442642-1652--111--3-1222--2---1-----------------------------------------45--1-----------------------1----1-233-5-2-111----3111-2-11-----21---------------1111111111-1111111111111111112231--21-----------------11111111-----------------------3333-1854---------------111-1-211163112324221321421111---------1--1-------1----1---------------33--11-------------------------------------------------- 11--97A-734-2258453EBC5DEA63333228545533354322846A6EGE65643433123--2-2--21221312-22222---47343216471112443-5*E*53533A112322294462GF5-623122172231122--3314223167A93DB7312233481134JYGFF546242513HJ8667x * b.82.2.9 PhyH-like
[ 722] -----------------------------------5-1-----1---1-------------------- 326-1----------21-------------------5----4-------33-333-----33--123-2-2-----------236223--11-111---13121424-1--------------242423335262111-----231119111345525114211211115-1-3---2-1-------117-1-111111111111111------111--1----------------------------------------------------------------------------------------------------------------------------------1---1---1-13--1---1-55393655A-----3217522524223--------------1------23----4--------45213--1-------6666666658778E47-----------------------------3-----33337DDDBEABCCCCCBGIIIIFBBGEH77335744452---1342----24228432222222--3567641--356447778696AC6792422222--74335-3223426354644553663-43662221--1141111113211113114111--2331-------44443464444444444-4444453444444334333455446453333343333333334933333345-444344443444223122222211143344777255433135225----------2323222222222222222---------25331444442233311111111111111--64222222----------------------------------------------3521 -1-----------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------2132-11------- * c.87.1.7 ADP-heptose LPS heptosyltransferase II
[ 723] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111212111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 45222231B44233333343333333233333333334433333332333333333323333444444244444455555434443555362333433333435651482533353563433627B2847b5-45A3332734671353133252333345433432635434334444p3254487BB3A43353331 * e.24.1.1 Ribosomal protein L1
[ 724] 111-1-1111111111-111111----11111-----------------------------1111--1 -3412--1111-1-11122-21--2422222112221-22----11---11-112--5--111-222231------------2--2--------------11122-221--------------------------21122---13124-1111112111-1111-31112--1-------1-21111---1-2-1-11----1-----112212---111-4--------31-11111111111111-2111-----------------------------------------------------------------------2--------------1-----------1----11-----1-------2-4--3332-----1165611543432----------1-33533334223-5224222332114112132121223333333333323343124------------------------------1132147645655555233334454333323554434412223325225131454621---1--21111111-11-1------11-1--1----------111113--1------111-1-1111111-----11111411223122222211122221211222---14-1------11321221111111111-111111111211111111122222111111111111111111131-11111--1-2-122-2111---2-----111111122---11----------111111211111333322242222321221111111112-11122122111--22333331111111---1221111--------------------------------------1---1----1-1 ------2-----12232232222434222222243322223222223344344333322222223121-31121211112222222222242224333332234231253M7C77973443345735CB**I-B6C324462344434345327554357EF6B796839779J32111H---3213192622332111 * d.153.1.6 Gamma-glutamyltranspeptidase-like
[ 725] 1111111111111111111111111111111111111-111111111111111111111111112211 1341412232311132222-23112322222233333344134233331332322223113322226454311111111233111---222112112--13222423241111111111111111111111-11122222111323--211-1122111111--12212--1-----1----1111111111322222222122222232222222211132424344434311111111111111111111111-1111212111111111111212111111121111111111111-------------21111-11111121211111121111222-11-3121111111442111111111111111124442-1111214332213333333333323333-11111111241-3333332332331111112321222231111111122211112------------1-11122---12-----11141133323333333222323333212222733333411334121122122212221112521111111121211311111221121121121111111232242112111111112111111111121-1122431122312212332332232222222222---2111------33332423333333323-333333333333333333343445112333333333333333323333333--333333323333--12121112221123231111111111111113332313111234443344433333122211111111112223222221222233222222221111--11222222--------111-------1----------1-1----1211-111111221 ----111-211--1132121222121122111122212222222221223222212222111122-1--111112111111222111111222213-111--1111-13-2-1111-111111112111251-111-1-12-111-11-1111-11-121---41--1--41271111-----2-1---2--1-11--1 * a.4.2.1 Methylated DNA-protein cysteine methyltransferase, C-terminal domain
[ 726] --1--11211111111---1-21-1---1--1--------------2-2-2---1111111---1--- 22623---------31111-11112A11111231111-312212511-1---211-----22111311121-3332212-1-21112222212222----2--142332---------------3524222214321232111-331123311133213111222211111111112111112--1121--11----------1----1-1121----------------11--------------------------------------------------------11111111111----------------------111-2311111111111122111111111-142133421-12-111112--114333211111127882127313111111111111-342252332111633521243322722231223233111333333332221112111---111----------------------325332321222233242242225522222233512211221313311253362131111112-------111111172211-1111112122212225311111522-11111111--111111111111231111212121111-------1------2--21---2223------1-4221-1111111-11-1111111111111111111--12132211111111111111111111---12-222222222222--3211111111122222---------------11111111111232434636324331324-121--1-11----------1111322222222222221111223333111111114111111---------------------1121122222242- ----11--1---232547685557C665533343333533233343C67C7CDD7676354413222221214244433312222223323542212222313122-35322211133-21112221329M4-222232112322-331222132212212-121133134223121-2V2221334986872132442 * d.160.1.2 Carbamilase
[ 727] -------------------------------------------------------------------- ---432222223-27GE55-5L22BK555557KGGGCJ9D-B2A23232222533332--227256867642222222----------------------------------------------------------------------------------------------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--466B-----2254522243443222222222-2-22222222225-22222222222222244---------3--------------2-------------------------------6664---------------------------3--2222-------2112-144222---------------------432---------------2--------4------------------------------22-442244422222222222222222222-------------22222222222222222-222222222222222222222222222222222222222222222222222--222222222222--------------4422---222-2222---255555443332-44444444444444244----------2222222222222223223222222222------------------------------------------------------------ ------------2224886C987A78F77433344456565565663778A6E75474444446A2222C22628222224AAAEA---34384344442-447572-7--14222-223222242272EJ5-642222222222-222-222222222---224------CH28----------6252448--1---3 * d.38.1.3 Acyl-CoA thioesterase
[ 728] 11-1----111111--11-11-14122121-111-111111111--12-------------1-1---1 211-1------11111111-11111111111111111111----12--1131---1--111111-11111-11111-111111--1----11-111-11-21-23--2---------11----1--111---1-1222221112211112211111-1---111-12111--11-----11--1-111111111111111111111112111111111-1-11-2222221211111111111111-1111122222222222112222122211222111222221122222222222222222222222221222222221113511111115131-111333411-2-211111111-11111111-12-11---5-------1--1--1-2-1---1---1---1--------2-2-------1---------21111211111--------1----2--1------------111-1-1--11-------1-2----11111-11111113312111112111111111553311511134111112-11111-11111111211112111-112---1-11111-11111212211------------------------1111-31111-1111111111111111111111---211-11111-11111111111111111-1111111111111111111-11112111111111111-11111111111111-111111111111--14111111333214111111111111111113333333111211111-1-1-2-1-3111---------1111111111-11-111-1111111-11111-111111111121222221----1-1---1-1---1--1-1---111111111112-1 33--323-93413213424332333235433542325333323444433311412443333322323224262324323322222243422342222121132474-22167I855A6554574A9673Xg8-58C7485944B645564654B4565435744333D36642531224U6443396G94543153325 * c.61.1.2 Phosphoribosylpyrophosphate synthetase-like
[ 729] 11---14422222233-311112-51233323-----------------------------2----31 11439113----11ADB77-7855977777789666BBFH24945422--1-32423---258-4439932------1----1-----111--1-----1321136324---------------54-5252432433333--15162422222244222322222456A3222-22222-2244422-----1---------------11---1----1-221-------33----------------------1-11----------1------------------------------111-11111--11------------------------1----------------1-11------------1--3-13332121111152222-2324222222222222-2242232532212111225322232211145133332341111111141111333111111111111111111111111111111212113332233333323444335542442432A356212332111112132332352111111111111112212232111---2-----1211-2--1224247-3-------------------------11111321211311111111111111111111--12233------12221111111111111-1111111111111111111111221411111111111111111111111-111111111111111111211111111111311111-1-1----111111111-----112212132121111113221111111111112111112111111222221111111111-211111-----------------------------------------------2-2 1-1132--311--1233212122222211111111111111111111211112--1121111311121111111111111111111111-2131221111122111--C313435322222222343317B3-345122231222222112111232321--14121423--1216862L554A9F5482867711115 * d.129.3.6 oligoketide cyclase/dehydrase-like
[ 730] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----552-221-86B34444444444444343445444444444444444444444454444333232142233322122233333333597475A6444452DDB-A3FDKFGLOMB9969G9aQ8JAf*K1LDR8ABAIBDE99C897F78QAJHCE59B7857242213696-126823411N***4*Q2167991 * d.15.2.2 PB1 domain
[ 731] -------------------------------------------------------------------- 2222322222222222222-22222222222222222223222332222222222222222222222223233332222222222222332323332--23322333132222222222222232222222222233333---3222222222222222222222222222222222222222222222232222424244234422332222243332333342222222222222222222222222222222222232222222222222222222222222222222222222222222222222222222222222224433222222222222222222222223222233222234222212122221222222222222222222222222222222222-222222222222222222222222222222222222222222222222221222222------22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212222221222222222221-11-1-1111---------1--11222222222222222222222222222222222-22222-2-21222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211122222222222222222222222222222222222222222222222222222222222222211112222222222--------------------------24211222222223 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1129111114111-12------- * c.98.1.1 MurE/MurF N-terminal domain
[ 732] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------*KQMDUTHDCDDKHdZDdL**c4jRpIGDEODJPDBIECEOFCbIJDFQ576C*Z12111-11Dt------------------------ * a.77.1.3 Caspase recruitment domain, CARD
[ 733] ------------------------2------2------------------4----------------- 22H-----------------------------------------------------------1--------------------2-4224451-6------8614C9F24----------------1222--2422---22-----716----1111---1-----3212---------------211-----------------------11------3-----------------------------------------------------------------------------------------------------------------------------------2------------1--------6293--------B6D9724-35364----------3-86-4738628--64456847472487---844464419B6666666638881422-------------------------------13-352114DGGDGEB8AA6FED8BDD95ADCB363C-27784232396436-423132-6422-----5853A54----2-1------2457-873--2363Hg-4722424444-422222222253486--44-2368--32-23324232222123925B---F3-1------21--2-122222222-2-222222222222222222-111-----2222222222222222B22-2222--122222222222-------------C3A-7222222-----2--2-------23475CCBC4AC7285755111----------333B333336753311--3--442----116-8868BB----------------------------------------------245- --------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1-----1---- * a.3.1.5 Di-heme cytochrome c peroxidase
[ 734] ------1111111111--------11111111-----------1--11-2122--------1----11 111-211111111123322-23--242222223333323311-123121111222111--1131112242111111111132------2211-111---1412233232--------------1---111111-2-----111-14--------11111111-1------111-11111--1--------2-32323313113121212222242312-2222232222222222222222222222122226112222-21111--2221223121121111112111111111111211112111111112113322112121111111111-1-2111-111211221-111321-12221111111111-13111-----212231111121111111111111-22123212231-1222221222231111111111111121111111121121111-----------------------------11111-111111111111111111211111111111111--11112111122211111-11211111111113111111221222112222-11111212311212122-1-11---------------1-11112311121111111222211111121111111----121------23111322222222322-22242222232222222225321111222121312314333232-122221--211111111211---11-1114332-2122111111-----11111224211-111-111111111111111111-1111-1-1211211121211112112111111------2-11--11--------1-3----1-1111111111111111111-1--------2212 ------3-84B11142433333333343312223333333233222333332332333333322222212212222211222222133335343333333-33331-5B2844346C44343449A3A3Ab5-577334344444343344339363443-335443433834831443B332353353346233222- * d.240.1.1 Lesion bypass DNA polymerase (Y-family), little finger domain
[ 735] -------111111--1---1----1------------------------------------------- 112-2--2223---5KD22-2P--9B212225LMPR64LI-74I--------313-----214--24122------------1----------------------------------------------------11111----27475663-34321212124154595111111111111--------1----------1---1-------------------------1--------------------------------------------------------------------------------------------1-------------------------------------------------27332------1525---2--4-11111111111-64244752-35-311332333437122121552--14255555555523343-1---------------------1--------11Rw1-5C758B89ACD99998AABBAABB38H9T4F8512534383216782EC17-121211-------1111741---------------------------63---------------------------------2-1-41------1-1----1-1--------2-----------1--1222-2---12-12222--2222-2222222333--12-----------------12111122---1-111211111---------111112155---------------8776736-1-2-665637341565514221--1-11-------------------32322112-------1----11------------------------------------1--1-2-2112--- --------------22121232-7364222222----------111----48A9111------1-----1--1-2------11111-----11--------------3G4A-1-21---------------------------------------1--511-2313-111-111--A85v4448E879E1841-----5 * d.129.3.3 Ring hydroxylating alpha subunit catalytic domain
[ 736] 111-111111111111--------52324-22----------------------11111111111--- 121121-----11111111-131131111111322212442212224112215642122222513583222-----------71----1111-111----211111111--------------11111111111122222---21111111121111111111112111111111111111111-1111111111111111111111111111111111111111111111-11111111111111111111-----------------------------------------------------------------------11--1111111-1--111----1---11----11-1-11111111-1--2-1211111111141221111112111231232223-332343313J2-A554758779AB561116A53333EBK1111111121114111-----------------------------81132-112212222223211122472222132333432--224411111111221-123-22211111112222211-1--111111111-1111111-1221223---------------------------112211125222222222222222222222221-1211311-11122222222332222222-32122222223222222222222222222222222222222222222222221222222222222111122222111111233111111111111111------1111424444444775544255511111111112222122222222211111111111111111-111111--------1-1-------------------------11111111112111 221111--521-11122222221222211111111111111-11111111222221211111111-11-111112-111111-11111113121121-1111111--251F644547233333455352Ei416692422523411323242274334436515443347224531111K1111121242311231114 * b.44.2.1 Aminomethyltransferase beta-barrel domain
[ 737] --3212113333332131-11-157117442411335332324231252256513332332-1-3--1 213-12-11--1--11211-12113212222223332242-1-2-11---1-121111---21--22232--------2322-1121112111311----4-1-231-2--------------211111111121---12----13444444232222212224227762221122222232-----33-11233333432-2133411222-2333122-21211111-43-------------------1---------------1--1--------------------------------------------------12432844454552441333133312121-21114221-6111111111311211112111111344511212121--11-111113-34244442431-52233443536323-11121223211---------2-112311--------------1--1-----------11111-----22----21----11121111-12121311--1131-222511122111--2-1-----------153262-313112-122132231123611129632----1---------------2111211113-212-21-31211122111-2-23-23--1---2------1222132111-111111-111111111111111111112211---1121111111-1111121111111--111111111111---1-----1112-2411---112---------222221111-2133332--11-11122222-111111--122311111--34411323222221-----21331211--------2----------------------1----21222212331312 21113-1-52-112334522333736433121232323222223232426458723332222-1-122-21121-121-22111231112124213-1-1112322-246656447-123112166373EI3-34722133333522433332622223-1--52-2-1-124312454U1249872263-52221211 * d.157.1.3 ROO N-terminal domain-like
[ 738] 11----5333335533-2------F9AD3487------111-163-4--1856--------111--FM -32-4112111-11322----3----------611125241122--1-1-----3-------312141211----111-------111------------1--1-1721--------------------1-----66633---532231112232211112-11-322212111111111112-------2--11111111--1111-11----1-1-------------25---------------------1------111-111------------------1---1111111111---------------------------------------------------2---------------------3-3---2-----235473-3-31-122222222223-53435634742-133443641246-4-1211522231-211111111111--2-2----------11111111111111--------2--133337444471222233233333-1442-1-1--22-3323225213233--3222-22222223422122--1--2---------1--1-1--334342-----------1---------------11111512324211222222-2211-1-22-3--12---------1111-111111111111-1111111111111111111111----1----------------11--1111--111111111111---3---------123-11111----------------------222222334624232333---------11113211112222211222222221111----112222-----------------------------------------------6-- ----2-3-----214118713212-1245644432345444446458867678847932434---------------------------CBB1C6E---224-----1L-81112111---1111111-231-1-21-11--112-1-114-121---1215-36--------3--742I21179Ssa*9mO------7 * b.6.1.1 Plastocyanin/azurin-like
[ 739] ---1-11-1111-21-21111212222313-2231233232232314333133-3423112---2-1- 255-521222311112211-11--2411111133231324133513321111333241--63321153432-1111----2-11212266631A33---2222143333--------------11211112122122222---21311311111111111111125112311112111121211-1-32-1232334423324232423122233353321543------552111111111111111---1------------------1---1--1----111----3311111-122222222212222-----1---222-13111121112121222111212122----33412314--1-121--3222222-----314323221112411111111112-33243423321-3222222222231111121-12112211111111122211211------------11111111111111-2-1342212333332232221111335222221233512211121231121-1121--142-1231-------221443-3234222223222332322322345352242222221--1---2-------22141313121223211121232-112211-211-21---2212------22322222222222232-22222222222222222222222343222222222223323222222111321222222222222--1133333----143241112211----1--22222223223524434335342322-323-111111112--222222221-2222323222222222--22111111---------------------------1--------11122111111113 --11--1-----1125222-2213343-------------------1-23663533-212221--------------------------11121111111111112-1322111111111111-2111-131-11111111111-1111111221111211111121111711113331W3121255641411221111 * a.100.1.4 UDP-glucose/GDP-mannose dehydrogenase dimerisation domain
[ 740] 22111111111111111121112----2----1-122-11111--11--1--11111---------11 -22-4---1111------------1-------11114312-1---11--11--1--1---122-3-4115-2111422----2--1--2-1--2-----224--2---2-----------------1-212-2-121111-1-5-374178D--11------34--4675----11--11-1--------11-1111113-13-2-6-111-234-31--43---11-31-11------1---------11-1-----1---------1--1------21111-11--2--214131-11---2111211--111--12-1---32-3143-142-13222--3-1-3131262-2-5--------------2--4222-----12--1--311131----------2---2-762--2-2---211-12211-11-2-251-21111--------122--3--------------1133--2---11--------2--11--7-11-1-3-----123--11-1-52-1----112-136--1-1-211-1-22-17A44655-1-121-1--111-2--13-1-1-211-11-1-21--3141-1---1--8-33346244---1--11-11--12--1--41--111-1-113--1-----1-------22121121221124211-1111211221111-11--1343--22-2211121111121111111111111-2---1-----11--11-----111-113-1--1-1--3112515-211212-2--1---2--3-1146-1-2-4---------11---111111-1----2-4111-111-1---1------------------1--2-21-41--111-32-31111-------------- 1111121-311-45521332222222333333333334444443335512222233333222------------------------1115541454111112-241--G25897FB75444543FB4C5QqB-H6B3454644943444455494634566934351221H--42172DP66677BDBC3G7452---L * c.66.1.26 C5 cytosine-specific DNA methylase, DCM
[ 741] 11--------11----1--1----1111--13------------------11---------------- ---141-1111-1121111-12--1211111122223334-1----11----11111---32--2322313-----------121311-------------1----1--------------------------1-11112---2231-2---11----------11------------------111----23111111222121112211112222-114122------3211111111111111111112------------------------------------------------------------------------------------------111--------1---11----11-------2122222-----3-2231-321-21----------1-22512413--1-122222122122221122111-11-511111111134421114--------------11---------------33-1222211111111111122111111111221131--111---1-111-1-11-11215-----------11-----1----1-----1-11111-1111117-------111111---------2--1123221-1-1-11111222-1-22212--1113---1---------12-11112221111122-222221122221112211313222111111111111111111112112122--111111111111--------------3211---------------1111111-112-22221111311114-1-1---------2112111111222211--------1111--2---1111----------------------------------------------41-- ----222-42-1--11-2132222322----------111111---1122333532233333325124232272322222255537-111-1-22-111----533-482SLJBCR8888E778HI5G6ctF-NFB6972B9BN85E8A68759AJ87I6655mGa3633-SiC51--38-1---35232212152361 * a.1.1.2 Globins
[ 742] --------------------------------------------------1----------------- 1211132233322211122-22111222222121112222122212322213222122112241211232122222221122111111222212321--1111111111---------------1111211111211111111111211221111111111111111111111111111111232111111233434433434343433333333442223234333333333333333333333333333323232233323332322223221333433423334322222222222333333333433332222222221333433333334343322244433112253213211111111-11112111-111111111211111111211111111111111-11111112111-1111111211111111112111111112222222211111111----------2212332-331-112----1111112212223323222222222232222222222222223222333222222222222122432223211222211212121111111121311212311111232111111111111111111111111211322322232232333323333333333333--22222------22223222222222222-2212222222232222222222222222222222223222222222222223-322222222222--22222222222222222133222222222223222222222222222222422222232222222222223334333333334422222222222222113-1-1111111111111-111111---1--11----111--1111111111111---1 ----22-------------111-2-21-------------------1---312---31--------------------------------------------------A-------------------------------------------------1----1-----------4324V444239767-6446----A * d.218.1.8 RelA/SpoT domain
[ 743] 11111111111111111111111131111122111443444841111111211111113111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 87668984P886889763666666666666666666666545666666666665666466666666663766666762666656666666766667666666666788CAHAA99FB88A86989B9E7W*B1DBH8777878D648A65976B89A9C9EJ8899778AK66998878*8886889CE689889888B * b.40.4.11 DNA replication initiator (cdc21/cdc54) N-terminal domain
[ 744] 11---12111111112-11111-111111112------------1--11-111-11111-11111--- 1-223--1111-1-11111-11--21111112111111531222-122----222--1--22322224222-------1--11--1--1111111111-1111111111------------------11--111-11122----212112211111------11111111------------1221111122444444333232343322443433322212--11111111-1112112111111111111211-22-----2211221112122-11111---11------------11111111111111--------113-222222112111111111-212111211--12-11-111111111-1111222122222113221111111112121121112-11511311221122212222222222112222222212211111111111-122111111111111111111111111111111111211333323233333222322222223223332222-1222212222222321121-1111111111111-222311-111211111113231122--1111-21111111111111-1--------111111432211422222222222222222222222--12112------32222212222222222-2223222222222222222232222222222222222222222222122221-222222212222--11111113333111211-111111111111122222122212122221111112121222111111111-2224222222222311111111111111111111--11--------1--1111---------------------111--11111-111 --11111-4121--212222222222221111111111111111113222222223222222111111-21111111111111121121363233733322-1545--2433536666343333433626P4-53443344335333332334434343---23314A23611221624l5553547GC2642132144 * c.58.1.3 Malic enzyme N-domain
[ 745] 22-212222222222212111111211242221111111111122111113231222-2--2221--- 2-3-252444422333333-3133343333331222355631244341322-224313221121327334132222221---42222211---------23---22332----------2222----------12111231112332-----42----------2----2-----------------22-3-3222222222222222323334222---21--333333221222222222222223223311113332121552233-11242333222----33322222222222-------------333652333-2---2------------44-------12-3113213212--12---2--3-3--22--------43322344224--------------------322--11----------2---111----1--1111111122212--2-------------------------------12-2322222222224222222222222223222223--222--1221-2-3224-2222222222222223----232---2--2222----1---2-----1--12222122222--2-------23222222221221-1122333321-2223222132122-22-422222243652442222222222-2222222222222-22222444442222222222222222222422222222-22222222222222--22222----22231444221-1232233211111111112222223322222222212---------2-2222222233333111111111122222--------------------------------------------------2-2222--- ----34--422-45266543333464522222222223433334335444444412444444222222222222222-222222222225A263452222423244-2123----------------------------------------------------1---------3-222-----2274H94822-4232- * c.1.22.2 Cobalamin-independent methionine synthase
[ 746] ---------------------------------2---------24444--532-------1------1 2---4--------------------3----------1211-32121-111--1-------11--3-1121-1---1111223----11--11--11---23---924--------------------111---12----------1-------------------1211-------------1-1------1477979688277777735665677721241324333325A1112122122111212--42112-23-41112323332132-3223111----111------------------------242---222-13-53111-2113111144-2324-1---12---1----1------1113---3221-----22234---12-1-------------33133332252-522244247225323123412132-52---------3321--2-----------------------------21-22112212266653222223331222211A353564--4432142122437216111-3211122222---13123--211115-332-2122-2221--11-2112243-111111121111111-1-----3332-1232-23211121323322221241----1-1------46462635444544354-4555544555446555554788562134443444444434334A54444441-433333333333---1-------1--1633111436-333322216667621--1418788696465555243421---11-12233611111532335543211112-------122------------3------2-111211-222112111111----------121- -----------3-1-------------------------------------111-------------1--1----1----1------11--------------2----63-8B2214112222243263CD4-63632125223112221222432222----2------2--1----1-----2---2-----3-11- * c.23.5.3 Quinone reductase
[ 747] 1111-11111111111111111132222222411122222222222222222212211211111--11 2121221111112122222-42112222222222222222122222222222222223--2221322232111111111---221311111111---11-111222121--------11-----21121122122212112222122322222222222222222223321222111212212222222-222333333331333333224422333222322222222223122212222222222222221-1-22-----1111221---1-222---111122222222222222-------------2114311111221211111111111212211112121-22122224322112222221-22122113-----113222112221211111111112-22122122322-2332222222222111233223223221111111111111221-----------------------------11212111111233332232332222333323322344212444322422233222222111211111111111222112111111111111111111111222222222111-11111-11-1111112111211223211222122222323222222233233--1122211-11133332333333333333-3333333333333333333333332123332333333323233333333332-32133442333311-3-----122222322111111-11111-11222222211121222222222222232221--11111-23333222223333311111111111111221-111111--------1-1----1-111211111111111111111211212221311 ------1-----1111111111111111111111111221211111111111111111111-111111-1111111111111111-11112111111111111111-12-112111-1--111-121217E1-113-1-1--1---111-1--11--11----512-------1-21-191111131241223121211 * c.27.1.1 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
[ 748] 11-1--1111111111-11111111--11211111111111111111111211111-----1--1-11 2131211211111121111-121114111111211133332113242-211123111111121-23423211111111-11-111111111112---11-211211212---------------11111111111111111111111111111111111111111121111111111111111111111-11111111111111111121111111112211--1111111211111111111111111112---------------------1-111-------11111111111111-------------111222111-14-23111111111121112---2-1--1211122111111111111--12135444-22-2526771134543333333333225-33433537851-5554536666775522233423444342122222251122111-----------------------------2226222552746656452222557A222223447664512552325336463982211222212232222111311-2211111111111-1111111111111-3111111111112111111111111111222243323-2332322322233332222322-1-121111111122212314222422222-2232222222233223222222211123232323333323222322222221-22222222222211-------111122246111111-111111114444423111422222223322224333311-1-11-1121312222222123222222222222221111111111--------------------------------------1--1-111131- ------1-------134224464575622222222222222222222234334444333222111111111111111-1121111111123242222222112222--4----------------------------------------------------------------1-1111I1111111352121133342 * d.334.1.1 lvD/EDD N-terminal domain-like
[ 749] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111GNj-1-1-223222222222222222222222222222222211234365222221111--------------------------6H-29A7---11--1-1-BuQzMPMLUEJIDCIIDQJDOEo*L1KJVGHFFNDGJFDIJECKEDSEKEIcJEMFUH33434654DR-21-----1-CFHR2ID--54767 * d.166.1.2 Poly(ADP-ribose) polymerase, C-terminal domain
[ 750] 111-111111111111111111--11111111---22222222-1-11-1111-11111111111--- 1211111111111111111-11111211111111111142111111111111111111111111111222111111111-1-1-11-11111-1--2--1111111111111111111111111---------1-11111---1123222221111111111122222211111111111111111111111111111111111111111111111111111111111111211111111111111111111-------1-----11-----111111111111111111111111111111111111111111111111111112211111112121111122221-1111121111211111111111111111111-11-4311221121111111111111111-2231352211111113111111112111-11111111111111111111111211------------------------------11111111112111111111111112222121113233112221111111112111211111-11111111221121111111111111111111112111111211211111111111-----------111222321111111212111111111111111111-1211111111122222222222222222-22222222222222222222222222322222222222222222222222221222222222222111111111111111111111111111111111----------6122222222222332111111111111122223333323233111111111111111121222222111111111-1111-1-1111111111111111----1111111111111 2211111-721233311111111111112111111111111111111111111111111211111111112111122-22111111111121111121111113351222247344422232223B272Ed5-53A121142223-2214211312122122322237135361148C8*22265HAJH1D77565886 * c.49.1.1 Pyruvate kinase, C-terminal domain
[ 751] --11----------------12--111111-111111211111-----21---11112-1-----111 --------1----------------------------11------111----1---2-----2-2-1---------------31-112--------------111113------------------1211--1-2-1112----261-11113311331441-3--575413-----2-11--------112--1-11-1--111-21--1113---111311-------2-222222222222222212212-------------------------------------------------------------------------------11-1-------------31---2------1-4-----1-1-2-4--213223217447245445512221222227-66477355662-6338236636651723114-1111512------------1324-----------------------------14222-11111-----------------------1---------12-11--112122-21-1-111111111242--221124132423421113231-1311-11111--1--111121----------1------1--1-----2-------1----1-1--1---13--1-------1----1-11--1-1---1---1----111-------111-------------11-1-----1122--1-----1----------21--------12-1-1111111-11111111--11------6122221111111112111---------1----------------11112--------121----11----------1------22-22112221--122---22112-2-----12 44--554-D5544451555555555555555455555555655545555555565455555553511116116551111115554555558555555455465555-496B5258B4544644548552Ae4-586344443484454444434-1-3578444444484955646456h94461788A5A56589564 * b.40.1.1 Staphylococcal nuclease
[ 752] 11-1--1111111111-11111111--11211111111111111111111211111-----1--1-11 2131211211111121111-121114111111211133332113242-211123111111131-23423211111111-11-211111111112---11-211211212---------------11111111111111111111111111111111111111111121111111111111111111111-11111111111111111121111111112211--1111111211111111111111111112---------------------1-111-------11111111111111-------------111222111-14-23111111111121112---2-1--1211122111111111111--12135444-22-2526771134543333333333225-33433437851-5554536666775522233423444342122222251122111-----------------------------2226222552746656452222557A222223447664512552325336463982211222212232222111311-2211111111111-1111111111111-3111111111112111111111111111222242323-2322322322233332222322-1-121111111122212314222422222-2232222222233223222222211123232323333323222322222221-22222222222211-------111122246111111-111111114444423111422222223322224333311-1-11-1121312222222123222222222222221111111111--------------------------------------1--1-111131- ------1-------1342244645756222222222222221223222343344343332221-1111111111111-1121111111122242222222112222--4----------------------------------------------------------------1-1111H1111111322131132332 * c.8.2.2 IlvD/EDD C-terminal domain-like
[ 753] 113-1-2322223323--21111-2---1--------------------------------1------ 13914---------1--11-12--5711111333331369221311---11-2121----1-B-3495551-------1---3---1-------------1-245-5----------------------------22211----5-1-111---------------1-2--------------22-------1-----1---------12---1----21-----------1--------------------1----------------------------------------------------------------------53-24444344434-4------31-21-112-311332-213-------4--4232-----24FGH41337495111111111-1-A9E88CAD562-62241284318C7523-66144445564444444463331521------------------------------2351-45445ABBBBA22221BBCC22221285GCAD4-2665433118251A2131-1111-----------2211-3-4111121111--1113111311-133-4-------------------------222--4112-4-112222232111111--1-1----1---------1--2--3332322132-3333212323322332331------------------------51--1112-----------------------------321---------------1111111-214166663284464553433---------1---3----------1122222----------2--------------11---------------------------2222-----13-- ----111-----11-21222121121222232211111111112222211112211111111-----------1-----------------11-------1-1----263F23223822222426E252352-32422224226222222B1292623326N2874B6AD8B356-13-8---2344672761121112 * a.56.1.1 CO dehydrogenase ISP C-domain like
[ 754] ---1----2223112-14-----23--1121-1-2---2-1-132133-1111----311----1--- 45K-7---223---22211-121144111113333343574117596-2331CBC2-411232695C8C721111-111-1-6-----224213------2-2562C3C--------------2111211111-122257---51122-11----------1----122-------------35-3155-4-422222122-122121743323221-2313--1111134H--------------------3-1-22-2---1111331-112-1111111111-111221111-1111111111111111111---111153-15---1---2-231--1131221--112--23----3--13215-----E3221-----414331--1---122222222234-1121142148--FAA498FBCB8A2-1-12352212822111111113------2-------------------------------611-1----233434311113351222112313--11----151---1-2125-31---12----------1-21--3-1-1112-11--2222--2221-111713-----------------------------21-3-121-1222212222211122123------2------32231125445545466-465654555544366566657632-115242444445545434643-4453--133333323333---1-11112121114-2222223123231322------2---232122242212222-333111---1111---211111--1113122322222--------11------------1--------1--11--111--1111---1211-214441631 -1-----------31111111-11211111111---1---------1111123211111111------------------------11115111-1223-1-111---6-3-211--------------------------------------------11111131------1--1--J-112211211222-61331 * c.1.15.3 Xylose isomerase
[ 755] 11----11111111111---1---31131-32-1--------1------1----------------11 -151211111111-49522-25--69222225645458IN-767212-1---555542--23312274653-----------2---------------------1-4-----------------1--211----122222---13------1-------1---------1------11--2-334--------------1-----11---111-------1---------1--11111111111111-----11--11---1-11--111--1-11-1---1111-11-----------111111111--11-----------31-------------1---1-1-3--------34111-1--1-----1-3--4222-----435331114332344344444323-44644857764-422343B636336353176544435341-1111113---1313------------------------------236214D93754445524454336766561594C577512224344337598671132-3----------222212-------11--111-1-1-----1111111-13-------------------1-111----2-----1-------1---------1------1---------224312-3453333434-3444333332434443444454431127485888885858556343223441-133333233333---3-1-11----1-133---31211111---1------11224-223212-2--1-11123-------------1111111---1--11111111------21112233--------1-----------------------1----------------- ----113-321-1112343435277842222223212333333222544767DA54453222--1------------------------253323165651-1111-1217221212111111133132971-313111121131111111112111131211211-----1241-1------3-111322-11--1-2 * c.1.12.5 HpcH/HpaI aldolase
[ 756] ------------------------1--2-121------------------------------------ -1--1--2112111-2123-2111212222221---1----123--1-12-123212222--1-1112---1222333----1----------------231132212111111111111111-2213222221211111---3-111111111111111111112111111111111111132--------122222223-222221111111222---2111222222121111111111111111--112-1-11---------11------111-----------------------------------11------1----1---11-1----------1-----2--------------------12-2111------53424---1-1------------2-32722321113-31142222311233--13232122112--------111-11-111111-----11111111111111111111---1-22212211112211111121111111113321111---31111123221111-1111----1---111-223---1------11-----------12-13B-------1-------------------112--111112112211121111111111111--1-212------111111-1111111111-111111111111111111111111-------------------11111111--1--------------2111111111-1312---3------11--------1211113111112221111112231111111111---1----------21111111111111----2211111---11-1--2--------------------------11---1111-2-1 1-56554-421-3449BC588ACDBCB45585576776565663438B8AAAA956969566124241212422122123133331432333B4433343563656-2S66474544322343364483FT3-7672322323731424233244442422126423544412331324Q344545676ABA37A799G * c.69.1.14 Carboxylesterase/thioesterase 1
[ 757] 22111122222222211212111152221121111111111111111--1111122223242112111 121121-1----1--------3---4------46661323--111111-111422222--112--242122-----------2-------11-2--1--2334452--3--------------------------22233---232-2---322--21221222-11111111111111111222222213434444424444443344444234434455122------4132222222222222211114-2---------------------------1---1-------------11111111111111--111----2221--------1-11111-111121--31--1221111-2221111-211-----------1-12211-1111133333333333-3222222126--933634555544321--2343233437--------1----1-------------------------------2--111143223225231111-22422222-24232312--43312211322332---1---21111111112-211312-11111-111--212---1--322214111----------111111111-------11-1--221321111121211112122122---1---------21--1221111111111-1111111121111111111443--3312222222222222222211111111-------------11--111111111--22---------------11111111-31--3333342332321---11---------1222333333324522111111111111--11----------------1------------------------------11--1---3 12--111-521-11244545335765633332322344333332325434566733421444234233-2115232113133333414578342422231212233-44453533433543333334645J3-537463443333334443453334145851642111131151---1M-----21235212122112 * c.42.1.1 Arginase-like amidino hydrolases
[ 758] -------------------------------------------------------------------- -----------------------------------------111--2--------------1----------------------------1---1------------------------------------------------3-1-----1-------------113---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------1---------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21-1--5-qSJ-32232222222232211222211112111112224434456H44523444111111-21111111111111111-----329271341111121-2ZJQLYNTQLIEHEFHFOLDPIs*M1UKhEFDDMJGIF9HGFALF9gEHJIT5BJFME6789AD8H86-6658322--1123342116878C * d.3.1.3 Calpain large subunit, catalytic domain (domain II)
[ 759] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------L765334556799AHAA555489A3C86AD978BB67------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------1----------------------------------------------------------------------------------------------------*---------------------1--------------------------------------------4inb*NNLUi*Q*h-cLhh----* * f.43.1.1 Chlorophyll a-b binding protein
[ 760] 11-2-1-2-------12-------111-2-252X1--------3A13112686-1221--1-561-11 JNf-2--2--------------11--------1---1-------15----2-322--1--132-311644-------1----1--1--3345-6121---A862A45A7------------------1-11--4-55576---C---1-----------------2--3-------------12--1-----2-----------------2223-------2--------C1---------------------------------------------------------------------------------------------2-1111111111--11-111--2--7----2472-132---------D-A-------------------------------------------------------------1---------------------------------------------------------1-1-------1------111111--1111-1-1--1-------------------1---------------------3-3---21-------5-151A--2125EB-1---------------------------1----43-124-1112---211-41-3--1---1-------------1--2AA4242621-A225258365D54212431111---------11-11-1-3--213312121------1----------1------------1---------------------------4----1------------------------1------1-1---------111--------222211--------2---------------------------------2------2 ----314----------------------------------------------------------------------------------------------------4-4STMJHIDB97A5ECGJAG5W*M1MCU8B8AH9FAD5E878FA9K9JD9B6CF355B3V72O43B8----1-1--12--1-31------- * b.3.2.1 Carboxypeptidase regulatory domain
[ 761] 32111212322323431112111-311321321111111111111-11-1331111132331111133 -112322322322232222-2222232222222222335343332223222233333322334233434322222222----6-1123222212222112222232322---------------11-11111-11344441112311111111111111111111221211111111111113333412-31233333333233333323111233224432211111122-2222122211222221112113--111213333221111-12111111111112222222222222211111111111112222222221----------------------------4--------------111-2--3-2222222222224555333333333333333333-224225233224222232422244342124333233343222222223222222211-11111-----------------111111131123333222222343352222344444222336211222531222131231111231111111111111423----------------------2-3323311-2222111111111111111121243111--121-1--21111111111111111112--13221------11111112111211122-122211121211111211222211--11111111111111111211111111-111111111111--11111112222212131-1111-1111-11111111-----11111122111222211111111111111--------------11111111111111111-222222------------------------------------11111111112422 22-2221-41211111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111211111111114122311313322422112543-32422122212122-2122132322332222281223111222221R2222223241322222221 * d.52.8.2 PaaD-like
[ 762] ---1-11-1111-21-11111211222313-2231222232232314333133-3422112---2-1- 255-521222311112211-11--2411111133231324133413321111333241--63321143432-1111----2-11212266631A33---2222143323--------------11211112122122222---21311311111111111111125112311112111121211-1-22-1232334423334232423122233353321543------552111111111111111---1------------------1---1--1----111----3311111-122222222212222-----1---222-13111121112121222111212122----33412314--1-121--3222222-----314323221112411111111112-33243423321-3222222222231111121-12112211111111122211211------------11111111111111-2-1342212333332232221111335222221233512211121231121-1121--142-1231-------221443-3234222223222332322322345352242222221--1---2-------22131313121223211121232-112211-211-21---2212------22322222222222232-22222222222222222222222343222222222223323222222111321222222222222--1133333----143241112111----1--22222223223524434335342322-323-111111112--222222221-2222323222222222--22111111------------------------------------11122111111113 --11--1-----1125112-2213342-------------------1-11562533-212221--------------------------11111111111111112-132211111111111112111-131-11-11111111-1111-11221111211111122111711212331I2111255541511221111 * c.26.3.1 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
[ 763] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------1------------------------------------------1-11-----------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 3322622-2-2-333--1111111111--1---111-------1--111112-211112111-----------1-----------------2-11111-11---2--1K8EMJKGPSWaOQPTOkeHgN**i2hX*IOQOZQLdQESSLIWQHZLEADH7A92D731123311A81532B1412-9228-43746D45A * a.39.1.2 S100 proteins
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a.4.5.11 Helicase DNA-binding domain
[ 765] ------------------------1----1-----4-1689691--17-------------------2 -3--2--1111----------1---2------22221222-1113----221343113--1---423542----------1----1--------------------------------------1--111-1---1--11--12-12-621---22----1---1-4341------------22-----1-453333333213233336887753333339522222212F51111111111111111111111112211111111122211------1111-----------------1111111111111---------11965A88887682543555121233311623538A484358122221-1--51---------11224---35244------------1-2--322----211311-111--121--1221111132--------1----81------------------------------------322--2332311-11111331111-11124221--3351332321254-325--1122----------159195465889SABBG-LDJF9AL7455645155643-----------------66221--444142---2135555-3344452324535----611------53741434444444444-445444444444423433555477---535345555555553533223334--511222211222---1-----1--11-326------------------------15111115355223374233---------8112555555763443433433222------78221111--------B-----------------------------11--2----1-- --------------------------------------------------------------------------------------------------------------------------------------------------------------2-----------------------------1-----2---- * d.110.6.1 Sensory domain of two-component sensor kinase
[ 766] -------------------------------------------------------------------- --------------------------------------------1--------------------1----------------------2----1-----------1312--------------2--1-------------------4274431222212-11----3454-1-----11----------1--2-----2------22-----22------------------------------------------------------1----------------------1----------------------------------------------1-----------------------1-------1---2---2-----31---------------------1-1-211---3---2--132322343----1131222211-11111111---1-112------------1111111121111----1-1--------12232--------1-------1-----------1-1211---1111---------------1-1-----1-----1-111----21-----------------------1-111--12----1--11---111---------1-----1---------1--3-----------11-----------------------------1--------1-1-1-1--11-1--1-----------------------------------1---------1----------------1111-1------1---1-------------------------------------------1131111111------------------------------------1----1-11115-- ----124-11-1867AEB68778A8967766664435766676455A84598AF4369544446BA8A5BH7B5FAA8AA7EEEAG345884E5367766424B98-1j62973444133211131343RT4-B271322543213232133652222223266321248368A26A737324D8HCPPAQCD6hmlkJ * c.68.1.14 Glycogenin
[ 767] -----------------------1322-1-22--1--------13-21-------------------- --2--1-12221-------------------------11-----3211111-112-1---11221-1222-----321--1-1111113322-211---11141--1-1---------------111-1-1-22-11111---3-111111-22221---1-32--1---------------43222113124336464564656665334444666131333322222244244444444444444233434233223-3322111221--3113332331111122-----------11111111111112444424442-4132-------3-426--155432---1--------21--2-222-3-23-2---------1-3331-121232------------2331312-12--233222222212-1---3232122333--------1----111-------------------------------1--------111111-111111--11111111-211211222312222-1-1-2116---3------------11-12-1-3-131---1---1----1121195111--1-------1-11111111--13--441-12-11213333333533333335354-----12------22221222224255522-222255424225322222332333323344444443433434242233213--311113313211---------1111112-3333232-22211--2111-111---1-----11--121211---1--------134454444465443--------------1114--------------211------11-1---1111---1-1112222212111-111 --11--2----3463334446632324332222555333343333311443333333333331111111111111111111111-131324234322222133223-294H312112121111-211215C1-311-11111112112121212211221226344A9ABC--14-33211125----14--7443353 * d.159.1.2 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
[ 768] ------------------------------------------------1-1----------------- -2--------------------------------------------------------------------------------------------------2---A---------------------------------1---1--------1-----------------------------------2-------------------------------------------1----------------------------------------------------------------------------------------------1----------1--------------------------------------221---------------------------------------------------------22-------1----------------1----------------------------------1-----------------------------------------------1--------------------1------1------------------------22-----------------------------1----1----4------------------------------------2-------------------------------------1----------------------------433333333334---------------2----------------------------4----------------------------2141222-----------------------------------------------------------------------------1-- ----22---1----------------1-----------------------11----21-1-1------------------------------------------------8**nq*aMJLLORJoSJYLp*S-aLiLOMKkNOWHHSJHETKJoLaFJ*11--1-1-------1----1-11-----1---------1- * b.11.1.1 Crystallins/Ca-binding development proteins
[ 769] 11-1-21111111111-122222-1--1--------------------------------------11 2222211111111111111-1111211111121111213322311111111111111111113111211111---111121312222222221222---1122413111--------------1222222222221111111112433233311222222223222332322322222222231111--2313222222222222222222222222122211111111122111111111111111111111--1--11-1-1111--1--1--1111111111122222222222221111111111111111221111112-121111111-1-111111111-1-112-11221111--112221-11222322411111332332232222322222222222122222422222222222223222222122--1-----1122222222222223121121111111--2222222222221----124222211112222323434433224444122322222-211222222222222222311131111111111222121-11---1111111---1----1222221112212222222221232222222222112222224-22122222232222222232222-122122-----22222222222222222-222222222222222222222222232222222222222222232222222212222222222221132222222222212222222222222212222222222222223333343333233333311111111112222222222232222222222222222111-222222----------------------------------------11-111-211 11--11--1---111221112112122111111111211111111-2111122211221111111111111111111-1111111111114121111111111111-11231434211111111111314A4-313111111121111111111211222211211-321511212111H1221242341421131111 * d.96.1.1 GTP cyclohydrolase I
[ 770] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3311MH7-B45-779438666768755665666565686676655577777989477747755355553354455454545555535557763777776655577A1GDVMJKFEKFBAC6ADCOI9LBi*H-HGR7A97FABGC7E898EB4MCE9BB57ECD98598AC78F51112B323111ACH7E22345755 * d.109.1.2 Cofilin-like
[ 771] ----------------------------1-1---1-----------------1--------------- --116112111---24233-32--4333333252222632-2-2111--1--123123--22--11-2321-1111--------1---------11----1-211-1-1------------------1------112212111513411111--11113132211111211222111212-1---------11111112212111111321111111-114332--------1221111111222113331---1-11-----11--1-1--------111--------------------------------------------11----1-111---------1--2-2----1-11111-----1-1--1--2--2111112-5232222-22122222222221-22222123151-2111-12-11-3213-112121222-2-------------3111-11----2-11---1--------11-11-41-311----212-131111133--21121-31-11211-212---11-1233--12-1-11211------12111133-11---111---121----11233333-1----1--------------------111--3--221---1111321211-21---33---1111--------12------------------------------------1211------------------------------------------2-----1112-232------1---------1111114-1-1-43343322322221421-22222222-222------21211--111111--1111--2-11--33---------------1--------------------111111-1-111-- 12--647-522-355223221212354221132112111122112214233335522211123212532442314463542234461113322113534111321512CA9B567D833546629829-**71B7B546362396463256534555453737342334452623-333F244415A9A2B243OBQE6 * c.69.1.13 Thioesterases
[ 772] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--k*8-841-2131-12224222-21122221121111111112--22222212212121211----1--121------11111----11-1112-224-1232-1W3*UTPOZJFADEEMKURESCh*V3RMf7EI9LFIXN9HBF9K8BUCRHEK579AIHC7H8B822f6-1384453--4IBJ1J412-F655 * b.8.1.2 SIAH, seven in absentia homolog
[ 773] -------------------------------------------------------------------- --------------------------------------------------------------1-1--------------------111---------------------------------------------------------111-221--11------1---11----------------------------------------11--------------111111----------------------1-111111-1-11--11--1111-----------11---------------------------111--------------------------------------------------------1----------1111---11111--------------1------1--------1---11-11-------------------------111-----------------------------------------11-1-------------------111--1---1------------21-1---11-----112-11------------------------------------------11111111111--11--111-------1------1---------------1---------1----1----------------------------------11----1--------------1----------------------------------1-1-------1--------1--------------------1-----------------111111111112111--11111------------------------------------------------------------------- 11------311-111-221----111311----2321111111---1111332433211111------------------------------2--A-----------141MJWUYXSHFIIEHISOJPGi*O-TPXFLKIQIGLIIGFJDMIJQJHKIMAABOEHQBGDFj578823414---43598819L54DDAE1 * b.74.1.1 Carbonic anhydrase
[ 774] 111-111112222242112222113333112311--------1--1---1112-11111111221111 1221311211211141111-12111311111-222236CE132213141--1122221--32321453342111111111112---1-2222-2113--143431-22411111111111111111-11----1122222---211121111----11111111-12221-1-----11--133322--1323222222222222222373333223344333211111133211111111111111111121----1-----11--11-1-------111111111111111111111-------------1111111111-211-11111111111111111111111411--111-11241-224-1112-12224111111-111211-----22222222223-112--2-12111111111321112112321121111222--------1----1221111111111111111111111111111113254-221222222221111122231111112233543--22131123222111121-1--1212222221112-12-412111111221-2232224222222342211111-----111111111111111--22-431333312222222322222232222---4221------1-1-1111111111111-111111111111111111122211111221222222222222221111-111-111111111111---322222343423212111111-111--111222222222222333333334333331111111111111-1111111-1111122222222221111--11--------------1-1-------------------------12212111111211 33--222-72112211222222222222222222212322222222222123221222222222212222222223333322222212222122232222212333-23442222312111111112123E2-2231-1121121112-11113-11232373311152421142222-----43747724A3454442 * c.58.1.1 Aminoacid dehydrogenases
[ 775] --------------111------2------1--F11----11--3-------1----12--11----- 358-----------------------------1------------1---11-112---------1-----------------------****-*EC---c*NkU*F*K*---------------11-312111H41221----42----1--11-----------5----------------1----1-------------------------------------------2-------------------------------------------------------------------------------------------------------------------3--4----21----1--------1-Y-1111---------------------------------1--1--------------------111----1--------------------------------------------------------------------1111----1111-2---1------------------1------1-----------1--1-7-1------------4-1-131-125199------------------------1-------1-2--11-1-----1--------1----------------------------------------------------------1------------------------------------------------------1-----------------------------4-------------------------------------------21111334--------11--22--------1---------------------------1----------4-7 ------1-------------------------------------------------------------------------------------------------------A111113332-232E62344J424361322422961344253184323411-1----1--3---------1----1----13------- * b.3.2.2 Pre-dockerin domain
[ 776] 11112121122222221221122122221222121111111111111111111111112121111-22 1111311111111111111-1111111111111111111113123111111223212111221211132222222222111211111111211111---1121111111--------------1111111111111111111111222222222222222222222222222222222222211---11112222222222222222212222222222212322222232121111111111111111111111111111111111111111111111111111111222222222221111111111111111221111111111111111111111111111111111111111111111111111211111111111111111221111111111111111111-22122122111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111211111111221211-1111111-11111111111111111111-111111111111111111111111112-111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111-----1---1--11----111--11112111121111211 1111222-311133433333333333333343333333343333333333333233333333332222223322233-3322222234423232425332132434121-5443645211122276281BM3-63511225-2211222121162342322422232B23523212332K4323254573452242222 * e.52.1.1 NAD kinase-like
[ 777] --------1111111-12------2----7-------------------------------------- 674-G--1111----1111-1---12111111----211-2--7754-684-532-----112182447225222122---11-----8874-6-----3B12244224---------------11--11---1134421---2-------------------------------------------55-2-1---------------12221---11-1-1111222231D---------------2----1-1-11--1------11----11--1----------------------------------122---222-1--26----------4----11-6-11-1-3------1-2---1122------8662------1-------1---------------11-1111-----4--2221111----613------------------111----1-------------------------------4-2------2222241-22211--23342221----1----11-------121-----------------2------------------------------1--3-----------------------------1131-56-2-211111121------12--4-------------12222111111111111-111111111111111111112222---1111111111111111111111111--222222-2222---------------1-3--------------------------411111111111121333-------------1-----1--1132565665552232---1----------------2-------------------------2-11-3222216-2 ----11C------11CEFCIFI9MHLI3333334334333333333EBCHKOcVMGHB9899533-2-----517---3--22112--1A8AE7B23773223526-1L----------------------------------------------12-113126K------------------2-AEDQBH63-RLRW5 * c.23.11.1 Beta-D-glucan exohydrolase, C-terminal domain
[ 778] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111--1--1--1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111--------------------------------------------------------------------------------------------------------------------------------------------------- 1113766-94325653443444444444444444444444334444544444443444444453344413444335525642333377736B4555655535579A15B4BQMKVJKEEEBEFDZQCQEm*I6OFgAGECIEGHC7FEEBIB6UEFCGE7ACC6484B56P58A52333S3332474384876555553 * a.118.3.1 Sec7 domain
[ 779] ----1-----------1------11--1-1-----111222212213211121--11-1-1---1-12 -11-111111111-11111-12112211111-22222245121231-1-221122111--111221352211111111-11121-1112222-211---1411121312--------------111111111211122122221-1121222--112---11-211112-------------233----1-12223233332333333--22123332332-2233333334222222222222222322321111341121222112221211234433331112112222222222212222111111212212221113--1222222222121122222221-111-112-11121---11----1111-1222------224321-12212211111111111-22523423151-32223343431322111---1-11--122222222-2222322------------1-11-1111-11------11221111-1222222221112222222211223343412322332224232423321-111---------121121221-121-212221222222112112111122----11111-1111111111122-33222--1-121222222232222222212111--1--1------23222222222222222-2222222222222222222333222212222222222232222422222221122222222222211-1-----2222-221311111111111111122222221112233334343133321444-----1---1----11111-1-1111222222221111--1-11--11--------1----------------------------111111111-111 ----33--217-1135334555566663344443334444445434343333334433333333222212212428314322223422235335452333133675-222------------------------------------------------------------1-----2122-----231332---65572 * d.328.1.1 CorA soluble domain-like
[ 780] ------1122222221-31111------1--------------------------------111---- 343-4---------------------------------------121-12--1----1----312-122111----43----3-----4464-2-----13-11211-2--------------------------222-----3---2----11-----------2-211---------------1134-21----------------2322-----1----11444441-4--------------------2321211-313111112--1-1-111--------1111111111111-----------------------1--35----------21--14413------3-1------3---1121------311---------1----------------------------------11----------------------1------------1-----------------------------------1-1-111111111111-------1------1--------1111------------1----------------------1-------------------------1-------------------------------11-11-2-11-------------------------------2311-2-2222211121-212231222121233233122211---3332333333233323111-2221--111111111111-----------------11111-1--------------------3-------------------1--1-------1----------1111111111--------11--11---------------1---1--------1-------121111-131-32- ---122C-212-123A7A8978597AA33332322211122221114645788787656555123111-111213-111123331234467773452222122533-488Y9C9DFB55578A88G5G6MpB2A8L65669377466666G53G5BBB78JX8CH988481754C3224b44327G6AB8541255574 * b.71.1.4 Putative glucosidase YicI, domain 3
[ 781] 1111-11111111111111111122222222411122222222222222222212211211111--11 2121221111112122222-42112222222222222222122222222222222222--2221322232111111111---221211111111---11-111212121--------11-----21121122122212112222122322222222222222222223321222111212212222222-222333333331333333223322333222222122222223111111111111111211111-1-22-----1111221---1-222---111122222222222222-------------2112211111221211111111111212211112121-22122224322112222221-22121113-----113222112221211111111112-22122122322-2332222222222111233223223221111111111111221-----------------------------11212111111233332232332222333323322244212444322422233222222111211111111111222112111111111111111111111222222221111-11111-11-1111111-11111223211222122222323222222233233--1122211-11133332333233333333-3333333333333333333333332124343444444434344333333332-32133332333311-3-----122222322111111-11111-11222222211121222122222222222221--11111-23333222223333311111111111111221-111111--------1-1----1-111211111111111111111211212221311 ------1-----11111-1-----1-----111-------------11111111---1111--11----1----1------1111-------1---1111---11--12-112111-1---111121218F1-1-4-1-1------111-1--11--11----412-------1-111191111131231223121211 * a.46.2.1 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
[ 782] --1-1--111111-111111111------------111111121--211-121-1111111------- 231--1112231--21111-12--21111111211111111111111-111-1111-1----11111111111111113--2122-1111221111---11-12111121111111111111112221222224211122---31252422433111111112235332221112221211212111111-2-222222222222222-122-2222--2-222-------31--------------------2--22-----22--22-2----2222222333333222222222221111111111111343111332333-34-------3-3323333132-333-343111431-52-21113212222----------112211112111------------1111111121--111111111111--1---2111111----------1---1221-------------------------------1---------------------23-----2--2111------2-1---1-22---21312---------331111-253-122133111153535452422222274-----------------------3233222232--2-322222-2-222222-22-----1112------22222212222222222-22222222222222222222332211-222222222222222222222222--211123312222-------------2----232232-11112111----------1211111111111112111111111111222222222221212--11111111------3311------------2-2-------------------------22222211324312 --11222----11111111111111111111111111111-111111111111211111111111111121111111111111111---121111111111--2-2-1--2A445867337434445648X3-5371547333432354B33135424314C21143211412321779*65765B5CB158------- * c.87.1.4 Oligosaccharide phosphorylase
[ 783] -------------------------------------------------------------------- -11-1-21111--111-11-11111111111111111221-221---3111-1--1------1---12221-----------------------------3-11311-2--------------1---------------------2--3-------11111123--232--11----1--1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3111-----12111---1111-11111111111---1--1-1131-111-2111222211111111----21111111111-111--1---------------11--1-------------1--111112222222222222322222-24231113-1111-211111112-11-11111---------1--2-1-----------------------111122--------------------------------121111111111111111111111111-------------1111-111111111111-111111111111111111111111---1111111111-1111111111111--1--------------1---------112-1---------------11111111111-11111211111111111----------1--11111111-1111222221111111----11-----------------------------------------------------1 --12448-E77-8BA567476676756444444554555555555578565364656554552111-1----11------1-----22245766574668653443-4VIFBB78898866688C87B7Mv9-C7E6766B898668565865A866574595885365443784176Dc8CA57797E7H8687888A * b.82.2.10 AlkB-like
[ 784] -------------------------------------------------------------------- --------------------------------------------1-----------------------------------------------------------------------------------------1----------5223221--------1-3--11-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------6338-----33G572213321411111-11116-222121216E4-9445HHEELEHD21-74-757466375--------311--111-----------------------------13565--3443333435-333333424444254323232---1112-223-32512431---52--------12-11-11---11--------------1-124258---------------------------233221353-3134432274424326235256---11--------11---2-------------------------------2-1-2---22222222222121221------------------------2-----11111-944---11----------6654661-2111454445323435231131---------2113-----355124444444233------------11-----------------------------------------------1-- ----34----1---2DHF7GFGDFEAFCC7CABEBAACAC8CC555AAHTDHUI9E9BD899------------1----------1111391HCA71331--3211--322111-22---1---1114-154-13411--1--11-1---1--1111-222--211-----121----32-112311236133352232 * b.88.1.4 Glutathione-dependent formaldehyde-activating enzyme, Gfa
[ 785] ------------------11111-21111111-----------11-1111111--------111--11 1111211111111111111-11111111111111111222122111111111221111112221222211111111111112311111111111111--111111111111111111111111111111111111111111121121111111111111111111122111111111111112211111121111111111111111111111111111111111111111211111111111111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111222111211111111111111111111111111111111111111111111111-1-------1211311122211322111111121111313111111111111-11111111111111111111111111111111112311112211111111111111121111111111111111112111111111111111111111-1111111111111111111111111212122111111122111111111111111111111111111111111112111111111111111111111111-1111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111112111111111111332211122211111111121111111111111111111111111111111111111111111111111----1-111-111---111111---11111111111111 11--332-421-12222121222323222222222222222222222222333322222222333333233232333-33333332333242222222233-2435-16226767733456444764G3Kb5-7463442534544442554463554323223232634D21121333Y222216344143334J434 * c.58.1.2 Tetrahydrofolate dehydrogenase/cyclohydrolase
[ 786] -------------------------------------------------------------------- -------111-----------2----------21111111------------------------------------------------111--2------1---11--1--------------122-222111-2------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1221--------1-----1-------------1----------2---11----1------11--1-222221---------1------1-----------------------------------211-1------3----223-------123-1--11---1111123--1-11112121----------1--12-111-1--------1-11-1-12--1---1-2---11-1111-----------------1111-1111111111----11111-11-------1-------11-11211111111111-111111111111222122222211---1111121111111113-1111111--1-------------------------2------------------22112121111-111111111222211111111111111-11-43332111114444444352--------11----------------------------------------------------11 -1--2---1------1-11-----------------------------------1111------1-------------------------------------------H4OSMPJGLHGA6DhD*j9VG**O-QKW6DCGVGBVM3E9GAS97O6G65711--28GPC9G7892--211J222335465-39551---9 * b.60.1.1 Retinol binding protein-like
[ 787] ------------------111111111111111111111111111111111111111111111111-- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111-11111112211112-1111111-11111211111111111111111111111111111111111111111111111111111111111111111-111-2222222222222211111122211111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111321122222221211211222232111-321111111121111111112111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111222111111111111111111122222121111111111111111111111111111111111111111111111111111-111111--111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111-111111111111111111111111111111111111111111111111111111-1111111111111111---1--11----111--11111111111111111 3222542-B443335222222222212222222222222222222222222222221222222322222233222333332222223442522232222213244424L653545433232432893436G5-335112233334242233-144343434233333333B332248A6R6664556492888955566 * d.265.1.1 Pseudouridine synthase I TruA
[ 788] -------------------------------------------------------------------- 1221111111111114222-221122222222222211111111111111111111111111112231111111111111111-----111111111-11323322213111111111111111111111111111111111112-------------------------------------33322--1111111111111111111111111111111111211111122111111111111111111111222222222222222212211111111111111111111111111111111111111111111111111111322222222222112212222221132212322221121111111--111422511111222222223352233323233333166243442343122222223223523121412323311111111111122232221111111111111111111111111111112452223322333333233333332333323333333322333234333332314423444332222222333332412111221111111434445324445454231111111111111111111121111113322323434234444233445424335321-1222211111133332323333333333-33433333333333333333333333333333333333333333332333321333333323333111311111111124324222222222222222222321211133444456554555545551111111112333344444353333333333333111111112211111111111111111111-111111111111111111111111111111614 --------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------2---------- * d.26.1.2 GreA transcript cleavage factor, C-terminal domain
[ 789] ----1111----11---1--------------2221211-2111231--1----1121111--1---- 222-12-11161-22------6--21------3-1-2488--331--1-121669-22--11---1-511-1---1-----1---3--1-------5-----1-7-4----------------1------21115-------23-2--1------------122-1--1---------------1------1------1151-33--3-----1111--2211-2----1--222221-1-111--2-52412-B-A6-4-2--1111-1212-3-21----------------------------------------1------14-1--1-11---122-1-2-22--1---------------------1--2441----8-22323--6111----2--11-18-6874643E25--31273-165551-F1-5H44-B1-831VUVVVVVV8726-C-2------------1-----21----------7-5-2-1--F2348513----2112378265-u32129-23351-293231113--6-111-21------369--3-26-214774121--11-311--951243-----------------------1---1---3-28----11-P135-322--428--31----3--2------1132321432344143213546-411113222242236441122-152265315234533512-122211-534454244144--5------33312---1------123---1--2-1-12-412-3112-1--1----13251-----1----1---161161--614-G7F674142-11----------------------------------------------3-1----------- ------------------------------------------------------------1-1------------------------------12----------------1---3-----------214A1-22----------------------------1-1----94----------------------1-21- * a.4.1.2 Recombinase DNA-binding domain
[ 790] ----1-------------1111--3114--22-1--1211121111----374--1------------ 3-2-343211311-11111-13111311111222321233-21412-3-41-53122111121142426431222132--1-------787A-9------221124713--------------1--1-1---41-24454-1-1-23442211-11------23-223511-------1------------2155555545-64456412222256712212221222131732223223222222221123216-2314111772213433--1424222----1--1--1111----1----1---1---22111-1112-21483334323435-32211321221-112--11211---1-------21-32--------13-----111111--11-11-111-54354857151-599144265622--1-2124213211111111111---113----------------1111--2-11------111-11---1111-211------211111-13334--2--2111221121-1-1--1-1--3111-12----11-1-2-14-3622244221--1--221-11-321-3---1--1----3--------1-----551213-221115665--333323324143------2------22-1-4-4333434432-344442433433433344111123111232222232222222222222132-----------------3111111111211-3---111--------23333211-1--322433511223311122----------347454454356451-21111----------211--31----------1---------------------------11-------142 ----41--------442435444322322122234442221323321234564689333633212-11111121-11111-111-11225--222-4222-22--2--31--------------------1----------------------1----2----21--------2--112H222-111--4-15-15431 * b.81.1.3 Galactoside acetyltransferase-like
[ 791] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 331-454-3---77854456615766644555566644244445445655554525566555322445-14423244-445333235668784885C688755274-614ICICKIICDBBDEDPHBUAr*P1UGaC98CF8FFF9EC6CP99MBGICB5H8D9997BD8cCN87-271264-87I89H5D7223332- * a.159.2.1 FF domain
[ 792] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------1------------------------------------------------------------------------- 4545874-gIF588733555555555555555555555555555555555555555555655444444245544435455444444655684379966666A5B9A44C8BKHCEGB8A68889GCBE8NrB-CAG7975D5984586A6896B647898A887667967748666CD8r9998ESHHU5V*776A696 * c.108.1.16 NLI interacting factor-like phosphatase
[ 793] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------111111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1-1112A-32--4443333333333333333333333333333333333333333333333345545515755457727755555533335333343333333CCB294BESNLdIHCBECDEBRWCTEu*K-WJkCEDCCEFNJ7EEF7d7BbCIDFB26a7AAA4F78INF8A121171111132323121151122 * b.42.6.1 MIR domain
[ 794] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4--Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------5-----1111111122111211112-1111111111111-1-112231112111111-----------------------1111-111112-21111323121-FMNJPEXEGLGHPG*iDdG**Z1gO*DJFFj9GvVEJFHDTDDjDKEGG45CR8664C66I446D----8113G---1-1--------1 * g.20.1.1 Blood coagulation inhibitor (disintegrin)
[ 795] 22---1-------------------------1---111------------------------------ -1--3--1----1----11-1----111111--11124---21211----11---------1--1111221-----11----1--2-------1----------21------------------11-----11-------11-4---11-----11--1--1-1--2122-1-----1----2-3-------1111111-----111-----1-1-1--1-11--------2-------------------12--11121--1-----1-----1---1121111--1-------------------------11---------112----------2-------2-1-------------1---111--11---1--1--------111-------------------21111111-11----1---1-1-1-2--1-1-1---1----------1----1-------------1--11------11-----11-------------------------------12-1----11----111-1231--1-1--1-------------------1-111111111---2---1--1--2--1------------1---------------1--1---21-222211121-11111112------1------------------------------------------------------------1------1-----------------------------------------1--------1--------------------1-2-1-----211--------1--1------11-21-1-2-22-----------111-11---------11-----------------------------------1--- -1--344-E7523344343544444465543335444533355333333666595434343334445545544544514443334444427234233322332777-2L48DEAEDB97797CAQT7M8l*I1MFPAA97I89HE9BB77D88EAB7AA46574695847835552683I3234465B83334447543 * c.37.1.7 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain
[ 796] 11----1221112111-132112-21-2-111-1----1-1------1-12-111-1--111----1- 11-15--1111111333----21122-----11212412-155632311113331213--56213127445----1111--13-------------1--------12----------------122-31-121-211122---62---111---1111----11-2-111-----------153933---111BACAD9DE2DBD9CC342211CB923153632111-1122---11-1-----11-1121213144111-15611551-1-3245533344432223333324434344443444444343221122221-------------------1-----11-311------1---------------2331-------3231-21112111211222222-22-111221-1-24444513452212-11-121--1---22222222122-111-------------------1--------------1-1----333352322224312444432532134421333-11232111-1111212221--1-11-212312-1--1-2--11-----1-1121-11211-121-------------------------33114-11-1--112232-11111--1-1-11--111121--111213-12-3443333332-4334343333433333334-1111222423433343324344332213333--111121111121---------111212232---12--11-1--11------2111-1443332232222211122----------11------1-11231433332321111--1---1111--------1--1111---------------------11--1------11- ----1-1-------11---1111121--------------------12121212132121121------11-1--------11111-----2--111------4-2--2-223335221-4323441325L515452-126144225221312433144---5212245322-5--11--3422-1122141211---1 * d.113.1.5 GDP-mannose mannosyl hydrolase NudD
[ 797] 2211223-11111111111221224221112121323212222122321344411-----12222111 --5-D1-3-------1122-22--1222222--121532-15-41---113--1-1----575-52IAC8-1111-1-1244----1-3212-1------12-1413-3------------------111--1--122-12115-3-23--1----2111------23121-1-2-2-1--2-1---1214-155534333138213352--23114132121233444422-5333112223342111122412-22-12-3354342211421334513331213232241224215433322763233313311274633742464654432434BFD2-2-21231-751243593---342322----122--2-1--21-4232111111321111112112-21212431-42-433-1121245122-221-12111-321111111121--1-23------------------1------2--3---14--1-1-3446431111134651112125483322--211---11131-32212--2------------1---21---1-11211111212121223232222-121----1-----1-----------11222111-41412-11131-1----2-----1--111-1------12431121321111112-1113121111211111111211112B522111111212322123221111111411211111111--11111112214-131-1-----1----121-1-2-1--1-1-3221213264233211111111111111323421131541--1121-22---2112--1---------------1-3-----------------------------1--------1 1111211-311-------1----------------------------1---111---11111111111121-11111-11111111111111-1111-1111-112112-2-111121---11111-41342-216-12111112111121--13111111-1412121241111111-----11---2-311111111 * a.35.1.12 EDF1-like
[ 798] ----------------------------1--1------------112---112--------1-1---1 294-9-222221-167733-3511563333336555C9BB-9444D26-321874136--389-659CEA31---3------1----------1--2--12-337-3-4----------1111----11---1112--33---2-C3212231222----1232-31558--1-------1--12-------28685748644556563321315552-121121443117A122-2-1-1111211-11122-1--------11-----1-222111---1---2--12111112111-------------3----------2-442224334-322411----4------2--2-----21---------7-26333----231745-1-3-1-233333332333-113117141A4-766366568755142-1163----214---------2211-41-----------------------------11162-211138775674222166456666149575475--1251-112214-5221212-161-------1-2-2----------31----11211---1--1-72-12-----------1--------1--12344-61271522-322241132232224323----1-4-------2211-1------------------------------231221-11-1---1-111-1--12-----------------------14-----121212715---------------------2---1-55453434221323111----------1-14735535546875231332241111-11-331111--------2--------------------------------------4-1 11--112-2----2211---12-----------1--11111----1-1--311-11--------1----------1---1------------1--1------2----29132-21132-2112-21-124A1--111-321121--1-12111121213-----2------1-22-12-11-12163-8-121-31--1 * d.32.1.2 Antibiotic resistance proteins
[ 799] 23223221211111222122222222222222222222222222222222222222222222222111 1111111111111111111-11111111111111111111111111211111111111111121111111111111111111111111111111-11--11111111-1-1211111-111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111122111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111-11111111111111111111111111111111111111111111111111111111111111112111---1-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111-1-------1111111111111111111111111111111-111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111-111111-111111-1111111111111111111 3422232-8222221123322222222222222221222222222222222222222222222222221222222221222222222222222222222212232413437464356454334494443CO4-6573544664455444463353454435743333843-43322334I3333355553333333335 * d.265.1.2 Pseudouridine synthase II TruB
[ 800] -------------------------------------------------------------------- 3331------------------------------------1---1---1--1-1--------1-1------------------33333-------------------3------------------------------------3---------------------------------------------233222222222222222333333222333333322222233------------------------------------------------------------------------------------------33333333333343433333---333--23332333433332333333--33333333----337473345844733333333333-6666636733333334433444334-3333336666333--------1443-565--------------------------------333332333444733333333433336364333333--533333333--363333333363-------333-33333-3344446445433333333333-3--3-4444-4444444444444444443---36-333333333633383633363366663---333332-33363333333333333333-3633633233336333333---3333333333333333333333321223233356666666664---------3333--834-------------------------3333333333633433555---------3333633333663333333333336------333333333333333333--------------------------3-33334233-3-- --------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1-------------3-----3---- * b.152.1.1 Flagellar hook protein flgE
[ 801] -------------------------------------------------------------------- -----------------------------------------------------------------------------------1----11-1---------------1-9999999EHKIINN1---13-111-1----------------------2-1-1--------1----11-1--1-------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CA--141115HA5H1276732-8484324-31-323-9---4--113544-1443-1-42123D41-7-12-2---2---------332--11-----------64557945D424554----3321128KHD4434443-222233--2222133511512-1-22-------1-3-2F--2-34336454461-2-11---1B---16-122V-----1-3-----1-1--111331225-214444344-11--2-------------------------1--1-------1-------58--49-5CDB78ABC8-8769B3A77B98C676765-1-23114674535634763635465468753--4AEBDDE7BCCA--8------1211--3--111-2-2311151-4-------111--3443A692256551948-------------1----------99455554556656--1-------------------------------------------------------B- -------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------1-----4---- * f.4.5.1 Autotransporter
[ 802] 22---11111111111-222222111111111112111111111111111111111222231223-11 1321111111111111111-11111111111111111121111111111111112111113111212221111111111111111111111111---111423332233---------------11111111111222221111111111111111111111111111111111111111111111111222133333333233333333111133322322--111111411111111111111111111111-111121--22--11-1-111111111111111111111111-11-------------111111111111111222222212112221---122-11211122111111112221--13111112-11-1111121111111122212221222-1111111113113222233333222111211111111331111111111121112-----------------------------11111112222322233321112222222222222222211111212331241321111211111111111111111-1211111111111-11111111133232111111111111111111111111111111222111211212222222222222222222-1-111111111122222222222222222-222222222222222222222222222222222222222222222222222112222222222221113-----1111112111-11-1-111-1111222222111111111112122212111112--1-21--122222222222222222222212211111111111111--------------------------------------1--1-111111- ----223-21--3333222222334422222222222222222222222223532223222222222222222222212222222222265323443333232333-38241111121111111121--3A1-111111111111111111121112111361311-111411212322Q2222245563654544433 * d.81.1.2 Homoserine dehydrogenase-like
[ 803] -----------------------111111111-----------1111111111--------111---- 1111211111111111112-121112111111222211112111222222222222222222222212222222222211111111111111111111-111111112111111111111111111111111111111111111122222222222222222222222222222222222221111111112222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222213133333333333321333433232111221122111121111111111112222222222222222222222222222222222-22223222222222222222222222222222222222222222222222222221111111111112222222222222111112222222222222222222222222222222232222222222222222222222221121222222222111222112111111111111111111111111122111111111111111111111111111222222222222222222222222222222221-2222211111122222222222222222-22222222222222222222222222322222222222222222222222221222222222222112222222222222222222222222112222222122222222222222222222222222222222222222222222222222222222222222222211111111111111111211112-222222222222222222311111111111111 11-----11---------------------------------------------------------------------------------------------------2----------------------------------------------------------------1-1-21811-211111-11112---1 * b.68.10.1 GyrA/ParC C-terminal domain-like
[ 804] --1------------2-----------13---------------3-1-3-2---1--2-11-----d1 74K13-------1-----1-1-11-111111-1---2122-2-4-----------1------212222-3------------------44TQ-6-----39162G5Q2A-----------------1------3-32241-1-4-21-2----1----1---2-1313231--11--1-1--2211211-1---------------------------------------1-------------------------------------------------------------------------------------------11---111------22------11-1---1----1---1-------1---51A3---------1123---1--------------1------1-11---1--1---11-11---111-2-1------------------1---------------------------------14--------11111-----2322---1--222--------13-------111--21111-----------1---17-31-1--22-----21-133---1318E25-----11111---------------11---5-15222-5433352322321332243------1--------1-----------------------------------------------------------------------------------1-----------3-1-------------------------32----11--1-------------------11-11111--1--13659545551111---1221145-1---1-13---------------------------2--1------1911 ----21--21-1114-123422-3333111111111-------11163212222-121-12-2----------1---------1-------11234----211211-3y**343D64875564979692Ho91C5D57657A6B766755747453323378AE45BD44F68B1-17-4-1--1-572241-26--32 * b.68.6.2 Serum paraoxonase/arylesterase 1, PON1
[ 805] ------------------------------------------------------2232221----1-- 111-11111111-111111-11--111111111111111111112122211-121221--1121111111111111112222-111111111-1111--11111111-1-111111111111131111111111122222111111111111111111111111111111-11----1----11-1111-1222222212222222222222222222332122222222212111111111111111111122222222232222222222331222222222222222222122222222222222222222222222221222222222222221222222232122133111111111111222111211-1111111-1111111111111111111111111-1111111111112111111111111111-11111111111111111111111111------------------------------11111111111111111111111111111111111111111111111111111111111111111111111-12222112111111111112222222221111121111111111111-1-------1111111333212221323333323233332322322--21111------33233323333333333-3333333333333333333333333333323333333333333333333332-322222222222---1-----1111111223333332332232232221222111222222222222222222211111111122222333332223311111111111111-111333333--------1-4------11--1-----1----1---112111-1111111 421111--3111222111-1111111111111111111111111111111111111111111122111-1112121111212222211122111111111111222-1813222222211112275251AK3-4351322211121222121143311221--2221111211312342B54431422313443-2214 * c.66.1.40 (Uracil-5-)-methyltransferase
[ 806] 11---------------1-----------------111---------------------1--111--- 312-2----------2211-1-----11111-----22-1-211---1-11-121--2--11---12131------------1--111112111------1111343-2---------------1111111111211111-111-3113111----111---1111--112-2-22111--2-----112-----1-111111121211-----111---11---------1------------------------11----------1-----1-11---------------------------------------------1-2-------------------1------------1-11-------11111-1111-----1111111111112-------------------1-11----------1--1111--11------------------1-111-----------------------------1-1---111122221222333322123233211212311112211111111111111121111111111111222211111-1111111113111111111-----4-111-1-222222111111111111111122211-1112222222222222222222221-1111-11111122222222222222222-2222222222222222222222222322222222222222222222222222-322222222232121122222222211212222222122221112----------11111111111111111111--------12222222222223311111111111111--11--------------------1---------------------1--11-----1211 3211234-733-22244222333232122334432322222-233313332232333223323232321233222332233332222222334243222233232225C48ABBF6E6443577JE4C7Is73C7E46547667816744822L7666626C34432723F33431233F44331521A2852146436 * c.108.1.9 phosphatase domain of polynucleotide kinase
[ 807] 11111111111111111111111111111111111111111111112311111122222221111-11 1111211111111122211-11111111111111111111111112111111111111111111211122111111111111111111111112111--11111111111111111111111111211111111111-1111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121322-1111111112211111111111111111111111111111111111111111111111111111111111111111111111111112122222111111111111111111111111111111111111111111111112-11211211111111111211111111111111111111111111111111111111111111111---------------111111111111111111111111111111111111111111211111111112111121121111111111111111111111111111111111111111111111111111111111111111111111111112211111111111111111111111111111111-1111111111121112111111111211-111111111112111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111611111111211121121221111111111111111112111111111111111111111111111111111111111111-1-111111111111111111111111111111121 1211222-612111111111111111111-11111121111111112112112111111222112111-1222112522411112232222111113121111222118177A549643A3554AN5C5Aj5-47C3355554732465454267444324243213511413431111M11121559A1341244474 * c.1.11.1 Enolase
[ 808] -----------------------11----111-----------------11----------------- 5641B2-22221-1BBB44-4A11A9444435CBBB76CB22292241-22-2-2-11--236-5-4677------------4--1--------------3-2161222--------------11---11--1--122221111-3-11---11-----------2-1--------------2111-------1111111111111131122-1113---2---------12-1111111111111111112---------------------------------11111111111111-------------1--111-----1-11---1-11-1-------------------11--------111----1-53433-----32H7811421331----------1-11411714247-85547837B544631121372122243--------232-12---------------------------------164-354266889885222288A8333313B8D79B8-28831136561B2A5-511--13-1111111--1512-5-3--1------1--1-12-1--222233--------------1-------11-123131-1223241111111-1222211-2-114--1-11-------35222211333133311-31113231213331111137864311-2-1211211121112142221111--311111111111---1-----2121-11-11111-------1---11111--11-1-222222421223322231------------3-------12133--2------------2-----------------------------------------------------2-- --11111-111----52222343342622122221-111111122222122324111311-1---------------------------1-221-1-11-1-1111-12244643582322333442438G3-436322153353223334325344441332311-32-4--21---1---------12---22-111 * a.152.1.3 Atu0492-like
[ 809] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111-1111111111111111111111111111112111111211111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 33212221B631322222322222222222222222222222222222222222222222212222221222222221222222223332332232222222243522424373343443243347473Cj4-5481343433623323233155544314233232621524533234m3333374A72542242222 * b.43.3.2 Ribosomal protein L3
[ 810] 11111111111111111111111222222222111111111112222221333111111111111-11 1221222222222222233-33223233333333332222222223222222222222222222222233211111111111111111111111111--1111111111111111111111111111111111111111111111221111111111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122222222232222122212221211111111112211212111111112111111-----112221111122111111111111-222222211111111111111111111111111111111111111112111111111------111111111111111111111111111111111112111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111121111-1111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111------------------1------11111111111111 12-1221-3112222222222422232222222343222232222222222222222222223333331343333333333443442221212216122113112212514222131222212366262GT4-642222242242221222224222233112222-233212222223G3223235492AD2232222 * c.101.1.1 Undecaprenyl diphosphate synthase
[ 811] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111-1111111111111111111111-11111111121111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111