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Summary of HM:SCP:REP&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbspGo To Summary without VIRUS
see 1-100     see 101-200   see 201-300   see 301-400   see 401-500   
see 501-600   see 601-700   see 701-800   see 801-900   see 901-1000  
see 1001-1038 

       aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppassfcffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoa ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
       ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammbojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitm fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa ppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppp
       eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuuacosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneu aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon cgprrstkaabbbbbehhhkpppppvwbmp1plpk4arrtabbbbehppppsssvvekmpssgppppstv4bccgpp7abbbbbbbbbbbbcccccdhlllloppppppppppppppppprrssssssssssstttuvl49ddhhlnppppppssssvtbtcbbfmppxpmreep
       rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieechhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo t1abdp3_5accccxjfppv4hhsshpcu1824s14ebm4pcimps116asfttpppsx2fphahhhi7p411pahz711aiiiiiiikxxhhhjo2k2cjjm3ghhhhhhhhhjklssy1oafkmpptttttmpult57333kka12hhhhhptttw1f52cceabhpmibhsr
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
==================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[   1] *****************************************************************j** *******************1*****************************************************************************IM*********************************************************************************************************************************************************************************************************************************************************************************************************************9***********************************************************************************************************************************************************************************************************************************************************B*****tvg********************1****************************************************u************tv****************************************************************************************************************************1********************************* *******n*********************************************************************************************************************************************************************************************** -2-D-C27-22222712--G181CA2-115-1---CED7E232221--232--143-3211111211321-1----11--31-111--1111--311235--324131124222511--1221--13-133332---11--111121222-2-2-11-2191322121-1tEGC1 * c.37 P-loop containing nucleoside triphosphate hydrolases
[   2] --------1212222--11-111-2----------1---------------------1-11-----1- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------1----------------------------------------3-----------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------- FFCGUO*-gCC9******x******u**********y*t*z**yuz****************sm*rokTv*twpqryWwyfsvuwyZfZ*******lghoZ*z***G**G*****************************************************************HCAR*HDFFG*******AE****8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.37 beta-beta-alpha zinc fingers
[   3] 22626178667666784222321AD45T3gF7DC688322323**BY*FR***1A97D6B232-D2A* fs*1*49DAAE892AAC87-7N11CB788878IDDF9GBFCREfO*M6LSIEXSQ87EDDNQHAb9IxtlGCACCABB62ID643B34ll*g3ZGH---H*yvv***b*33333333333333852I643798e4Vlkje264v9TjL6HJo5833545B443O2dJbO*333337333333SRI99FI6BE4MLMKNGJPGINHHOIEIDE47JJQ987HB94MQRTRH**G224443-444422333I227925324124377237525122265656798687335556577647441222456422226442223333OJAlS8888A898B8*4DC2RTF*Ct6AGQbn2YOf96JH72AACGRA22*3*C447-11-18BTNJI88C9MJA23322333339-IMKD*aGG866-F99NNSBSPUEEEBBCFD5EHIKKD4J777777777674BYQA11111111--11--11-1211----111113E6726FA7CPHIGHRGJLLLIIHGUWTRNPMGNGGJK39NVV*FE53mBBGR5DAUBB7CI3112222254DCGAY*9G67644442652***Oa**CCcr*f*YJdF2245555547333333333A449M8ASJBbG*h5jJUYnr*YnoUtYbcUxTlni*--7CC7E------ajHKPLUk**okpppzb-*di**dq*uo*r*kklrkgZVVGVRWfetaYdkfliefkodYgVKLOONRS9-qy*v********--3G323333533M5*5Y878889344256555997882815UD*MONLORRQEQOVNFMLP7554554456JRuOKUWTTmoVSZOJSYWYcPQO777754*6IICCXW22222222B5K----------1--1111---1---1JOD8AFKFGG9*EO EB6E***1*lhCcd*diujqiobpikqPRLRQRVWTPPOOMNOORQcTdkruw*ggofaighTOSKKMDJLJRKRNMHKKKRSSQQKJLanWidXeQOOVNnY*z*4********************************************************************G*************m**P****** ---3-311---------------------------112-2-----2--------33-2------1-------------1-1----------1----------2------1--11-2---2--1------------11------1223---1-12----212---4------1-2- * b.1 Immunoglobulin-like beta-sandwich
[   4] kfXXge**********v***pru*********kWgknWmxmon**q**l****V*******wpnrEk* ************z******1**ji**********************************CC************onn***x****bX*qj****S*wmx55n*********GGGGGGGEGHGGGGUfeg**vvw********wjy**********s**jhjrmo********UiSSRQRiRSPP***xzrrY***********************************************************************r*****************************************************z*****************************************************f*v*v*****MRQOg************************3***********H*******************************************CCBBBCCCBBGmGBIICGKIhCFGBE9IEO****v*********************************Xu***********************no*uwrp********************T******************YkdQXZWVTWJWGGIKGHIk*Yex********************************D1Q****978888*****************1****************************************************B************BC**foebh*************x*iwvvrytrx********************************S*b***y************************qhjkFE*y******EGGEEEFE*LeB8KAI1ABHCQCCAAADSMDECEEDo***nt*twwh*k* eejs***8*efp********************************************************j*************************************s******************************************************************************************** ---11--1-----1-11---1-2----252-----11--1-1--------111-----2----------1---------------2-21--3-3111-21--1--2--1------1---1-------1-----1----1---1---11-13-3----------1--1---3-1-- * a.4 DNA/RNA-binding 3-helical bundle
[   5] ihevip**********on***wx**ux*z*************************p*i****lipwGt* *****ptz***mvp*****-**ii***********************vuxsj****t*PP***o*******cbddeebbz************Y*kpOFHs*q*******DEDDDDEFEEEEFFZ**********************************************w*z*wuu*v**w******yl******************************************l*z*zyzw**zz**v*****pZeZhhexTVRsrz*efXeVbdUfcgaVVZZYXihgccbdddabcbbTRSSTWUWWYVPVqiikkjkegY**************************fi*******************luz*******VYXWX************************8***********P*******************************************NNLNNNNNJJHHLVPPRPQWLLNNLKKMMe**************************************h************************y**************************e*********************xz**zv*r*upmonnn*************************************M6b****QNMSSS*****************-****************************************************I************QQd*x*x*z***************f*****xz******************************xeijiwkje*****************************qq********LMLMLKNKzOgAAE9C-A8C98B87779CA898BBC**u*z********l *******C***s**********************************************************************************************m*************************w****************************************************************** ---1-1-------------1---11----------111-1----------------------------------------------------------------------------------------------------------------------1-----------4---- * d.58 Ferredoxin-like
[   6] **z**************************************************************Dwy *******************-**************************************VW*******************z************x***FAB**********UTTTTSTUZaXYYZi*****************y***********************************************o*****************************************************************f**orzl***yy***z**********************************************r*******************************y*****************************ageaj************************5***********X*******************************************SSRSSTTUTTCEHHJJHKPGGHHIHPLRPv**************************************u************************yz*xyzx********************l*********************w*****yw*tsststt*************************************XBk****aUMYYZ*****************-****************************************************V************RTd*w*xy****************t***z**********************************w*uy*yyw*****************************nl********OOONNMMM*Ox7786U-FCMINECKKKHOeFQIBBB************** jmSU***-***Z**********************************************************************************************E*************************F****************************************************************** ---1---2-----------7---11----------11111----------1----------------------1--------1-----------1-----1111------1-----1----1------------111---------------------------2-----35--- * c.1 TIM beta/alpha-barrel
[   7] 111141A9ACD9BCAD45343336745F3956M5JDHEHILINpWRf*OP***1CBAIFE84BC21BI s**6*226666221F9CBB-BG44JKAB9AABRLMMQFpfA*l*LP379CA6HPO766--iaN2*Vx***S4888554956PGTVdXb***wB*nt*11e*bj****h*HIIIJIIHKHLLLL*XKkckMRY**a*****666*I*******mufiPWOPTXrpg*****8cGRADC*7RFEpXcSRDBcFIOdZfXgfgmQeikeghaTRPTVbgkEKJZLFCKIJILJuk7987877878999A876679C676CD8632566558876733455644244326432434322154354666655466566554454442FVGnVWVWRUXXYZQITMMQFEFNPb43QFOGHXNMPEFGHDE8AME7S**i*iegjCB99Bhg***XYRhXfaoIJIKHIKJIIM-ZY*WX*WiT*d8oVTjtm****uphggm*jYUQUVaVYROOOOOOOOZWaNM*ju6645466523IUB9SV6DW887AC8757ABQfubjNXRQRtjklmmeTVWQbaq*gggdUe*o*ZkmgHWbWosWTTHoQXmfQNe*oYdlgJDHGJKKHbTqZdn****nZxxh**xuvX*****z*rs******fyKSPE9FEDEJIJMNPQPNROOLJTLaYgfO*w**Z*hlhlilfppodghhqiqrhu*--Kphbs331333RNJTKUKZabdZSVSaO-XbebcQSXXYZQYRUZTRcTOPXYJLQbTdUcPdcfggYcYWcQPHLPLPQF3SUUUUUQTURTU119hJRJJIcfegWR*PcMNJHSHBHCJKGDBMRPWQRKLKMGdxjkgjhqropgjeheegcC8A9AC998QZyyoaaabbtsmponiseofgghlMMMN8A********baZcccad*h2-------2--2---------1---1LLUIHGKHJHX*pb *******5*********************************************************************************************************************************************************************************************** --------------1------------------1-------------------------------------------1----------------------------1----------------1--1---1-----------------1---------------------I112- * a.118 alpha-alpha superhelix
[   8] WVKPKRtz*******uS*jkiget********fgbRSaTYVTZjnbklah*uvSbiWaZYghnjd3et *****xl****rps*****-****************************u**y******II***********dZZZeddLTqk*hirlg****O*ijE98k*t*******EEEEEEEFFFEEEEa*zr***wx********VWT*********rsuwzvt*wy**y*****roppruswwrlw*****xuU***************************************************************WtO**VyQPR**mn**rvjqy*zy*feeYUVUjjjfihehefgcdgRTVTTUTUSTTSTpdaabTZZZpn*a**yyuuxxyyxy*z**ehiY*kwXM*pjpg***vwvmqgjvrunNZh*v*****PUTUU************************-***********O*******************************************KKHKKLMMGGDEGIIJFJLGEHJFHKIMJ*****q*********************************b******************x*w***fjmjikhy*****v****q**s**vuzd*****************kikdZgedciZUkVXWVVWWngoqvxx******************************D6O**x*ECBFFF*****************-***************************************************uI************HHVpnrlno*********jfg*d*QYbXVhgko*****************************zcjdalfccn************************tjjjSO*q******88888888UES3332A-A6A59657778DE766222cgmhhprnsos*vz STUY***1**tK********************************************************v*************************************8*************************3****************************************************************** -----------------------5--------------------------------------------------------------------------------------------------------------------------------------------------55-1- * c.2 NAD(P)-binding Rossmann-fold domains
[   9] -------------------------------------------------------------------1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2----------------1-----------------------------------------------------------------------------------------------------------------------------------------------------1------------341-----------------------------------------11----1-------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------ XVdj***-*41***F53uYLWaNLBGQ575424DD49454344434VdQihgfnfq*vRKLP1-1-1-----19-------121--4-2Z2I3s772333-41114-*l******************************************************************7zTP*YVF*GO**ySvPEUMwWo* --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3--1- * g.3 Knottins (small inhibitors, toxins, lectins)
[  10] IGHDEEMQSZdXPQ*LNQGFGGEXellVUSbMNJLHLHKKJKJNSMJiOU*shNJdJMMKNJKOM8GC zm*p**o*vvo*Ypf*ylk-l*PP***l**yg****x***k***yw*qfb*t*uvdg*DD***h******gobbb**jVXnisVQXdUnn*sPtqYe79Wnakh*k*j*HHHHHHHHHHHHHHcffTo*pcbmirijlzwSXR*c*y*o*s*beffbZZbecizu*****VXWUUTTYSUVX**reVssX**tvx*x****z******x***sq*********j********fgecqYaZbhhgcaedgilvsu*b**o*frq*****vrkhxub***ZeW*p*nTYWoiaolgffqhjWjZViZYZcdbabbgdvschcdXy*v****z***********twy****fW*kt*k********t*****Vqcld**pp*IRRLYmf*****gozmgrrwxzuvttvy*5***lw**v**dL************w*ehh********xx************d*j*QQRNMNNNKKONQSPSRSfUuSQQSTNYSShq*lYgjn*********************r****oy**Pa****v**t***u**rr*fhbdzpbdqilkZ****p*h**pfhu*lwtntmT*p*************o*dSVRSSTSSTTQSRROSSNSboWcbsry****q*m*q*w***********x******H4XjqvqKKJIIJ*z**w*t**********-**************************r************************oJ************JJfeXZPRXvmpfwh*k**usodsXbjgaimrltgzn**ltt******zuuz*s*tot*****YYbabaYYh***************u********eecdOL*beb**mdSSRSSSPTeRUPNQGK-IFKKPHEIOQK*eFOHGGFn***l*****XsYb w*fh***6***f********************************************************p*************************************V*************************L****************************************************************** ---2-112--11---11--2-3-21--11-1----111121-111--112--1-1111--11111111111111111----1-------111--1-1-----1-2---1---2-11---1-2--1--------1----1---1---1--111----12--211-2---1-B3261 * c.55 Ribonuclease H-like motif
[  11] DDIIGFPLQPPPPPQOKSONMLKt*ZZuV*mlcjjWUVdbaYb**fx*bu***TQWQTVSVPNMN2Rg ***n*bcnjjkVfX***rs-r*UU**rqrrrz********x******tw**p***hjxCC***q*******khhh*jgSO*q*MPaaa****H*ad866d*m*******77777777877777ErjXy*hen**u*****vik*n*********uweZhqhh********YcYXXXZgZYYa**wiheeRyw*************************x******vsrutu**hpooopompoqqprnslnnkmffWstZmSSZ**mostYfafpcYZchkicVXYhghacabZZbaZaZTTRRSVTTVVTSTodbYYQYXZYx******************lw*q***YT****e*****rgzv*xsv*Llm*******PSRQR***************y****t***5***********G***************************ssssssss***nv***GGGGGGHHDDCHECJJAFHEDDGECGEGFRs***d*********************************Ob***********************MPRRSRSqr******************P******************bjeQZYZYYVLYLMLLLLL**fh*ih******************************F5S****775779*****************-***************************************************uD************EER*SWRSUnsrnw****TTUXVbESTQSTORc*****l*iso*******************WQPNPWQOQx************************roknKK*o******CCCDCBDBaBI44349-686887499988F777556cbYcZZfZYYb*p* HJ7A***1*SKHWd*************wwquruyztv*vztw*usw*****************ikTYbKhaXkZngiPkdcmjloqhko******v***yvhs***5***********w*******u*****5***x*zr*****m***m*wr*********z**rk*r**fl*va**m*jhg**************** -------2--------------1-----------------------------------1-----------------------------------1-----1-1---1----1---1---1------1------2---1-11-----1-------111-------------11-6- * c.23 Flavodoxin-like
[  12] 666666ABA99ABBAD55655554B67M5B7833443445654A466D45BB65454A4445443344 7Y*7*96899896BTUQKL-KX77hWKKKKKOYcgffR*r9*k*PiPCAEBAEFGC9D55LNP9uQh***WABAABBB557GC333222253-4137--12245B757233333333333333422322323424MNNYY111q7*UfcSPUGIAA678987KKKN*z*s586565585555FEG6721688AMLMJMIORBLHMLLJEC99ABMLL9DC9B97454454LN454343233455435346534244335322365334422112246523233353226446435433522222222322224335543332587BCBBBBCADFDA53AABAA9D7B533697456532547434344-65W2*F88A232237BFEG655BBB9A66666566769-CCBBAFBC6GD2D88CDCAIED9DBC4G4A94D9CA6696666666675454EAA111111111114122212311112111123A8D958776DECCECEDAAAABBFCB9AA6DEAEBDGA559B8FHCCACIHFG989ODDAD95333333355AFNC9JGF7693-86333-564753695PQSQ**3C21-------2---1-1--1143147778ADCDGE7EBAAA999DHDCBBBCDEE9FH--24AE9------8997878AABAAAABEB-DBAADCAAABCBCAABAABAAA9955487888A88A88C8A8A999CC9BD51A88898789898113A47756HOFJ6FUCD433453333343544A9A9C8B7A9IAOQSRILMLKJKLJNOIO2111111118EBDE66696CDCA9CDECICDABB444452B58889AA--------211----2-4423322222324236322-21--121--18C2 *******7************************************************************z*************************************b******************************************************************************************** ---1----------1-----------------------1---------------------------------------------------------------1-------------------------------------1-------------1---------------J944- * d.144 Protein kinase-like (PK-like)
[  13] SSRRZZVWXTUYYadZRXWTWZYWhZZcZalbVLMgiPWYdWZkxYi*TY***ifehedgYMSaPCoT Pr*M*STYZZVPQU*****-**TT****************J***kveVQWWHeikORa88***Q******qFGGGNIHPHMcbTNSPXbWba6YML754dienX*mncdABBBBBBACCCCCCRWcfiqmRTtuZ*****ILK*R*******oummgZZYdbu*b*****WbWUUVRdYWOVbUeZZNJHbdg********g******kkeccd***adcncaTdUVVVU**XRWNQONONPQQRNONJUPPULTKRSJNLNLSSPPTTOLNQNFPVTUWWMPaVVWYVVVabZVWVTWRUQQQRPRVUQSOYaYWUSWRUPUjhgtebfcdhmalZidywXVaVlUpOUYeceeuu*ZhdQcaWTSSaOWWgez*su*QaPLozx****rw*****XaacbYbYbbt-********z**J*ww***z*******ijkizxpmrujnrdcddddddwjkZq***DDCCCBCCDDPVLMTVHKTJGHKKHDADFPml*hNdhXUn*******z**y********p****uutxNYnptqy**otq**r*os*mcakvmiqebgegenn**zn***ictzf**rtib*****w*ux******n*WSUZPUVUVcSoahknroajmVQXanptumo*vpdtnpv*****vy*yxz**tu***6-Q*oqyA86AABtmtonolkpprlsqxsl-pkionoskqqptqijjiiktrqppz*pnjimmimkllmuoqmnomnimhlje9rnonsnkmnkrq88SpJLJKLqzsu*q*ilbYZUbUYdVVXgRdZddgefdhafWup*********z*v*****WTURRVTRTkmoornqotouruquvnyz*zzutseabcHD*jmmposnEEBBACBBZBOAPFAD-GCFFF86GFFGHG9JBDDBPPNOUPMQQRt*RQ **bg***3***W****************************************************yqoqeypl*vyqnboqrwuu**w*******************G*************************C****************************************************************** 11--12----111--11--1--36411--3----1-12-1-3111------1----2-1-------------------1------------11422--11--41-----------1--11------111------1-----1----21--212---------1---2---662-- * c.66 S-adenosyl-L-methionine-dependent methyltransferases
[  14] 877899rkqqwtrs*oGgGEHAAECEHEEBJG31332263432FNCDD64JB93EECDKGAtmmA-22 OTyP*MJoxx*LPRpUWWW-Wl55s*VUVVVVntvx****P*Z**sgcPiiG***hJ*44**lW*h****TPIKKmZS47cEi49657ZaYO4T444--CZFLHvKcBu44444444445555B88978666876WbdcX664XTPDHMAA89A9A889FKBEA9DSNTA4954434B3453bSPKNEAKoI*********h******hW**n****JVSkQWQRRSSTO**PZVWVWXTWXVVYWWgUUZnENjEXdEUKESusUXilMIRYbdTQOEDEDC98CAGA99CB9B8A998888988A89878A87AAC766BAE4ZhEEEGGGGEFEGMYY5EFAE2483J3754*mGEG7EDBHB8IC944G6G*ZZv7PE8UhT***QCVfkYeTNSRYMPVOQQs-kk*gh*o*QxZ2*llsrwl***qv*kQcQJTmPLNROLTcVccccccgpoUORIX7766677744BBHLORGLVHFGHHG95D86Kq*YHbmbZ********************x********6J***ORnZX*PiV*kWiQDHDIxJBHBCCBC79AMQOKPUBD7B6DJE78B6ICCQEDFC9STSVff7HF8985HHOKHC79778766889797OOaTUQQWYFdIJWZWXaSTVcXXNQMRYObc316AFAE33-223***yf*m**********-************************iro*****************vux****I3xjkkorlginom226CadTbZhkhiAERclHDDGEJ8AB898ACB*****SpFJL*S********a****W****gwiZ*ggg6MTTcOPPSPUUVTXxxllmmlWXWD99932B6II77A921-1-111A13----1-2154132333384532---FJEAABDADAAZGH VLJN**o-**lHTZy**************************************************q**o*vz*****o********y*******************7g************************7******************************************K*tu*jkm**************** --------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-- * f.38 MFS general substrate transporter
[  15] 11-81-455555556621434-217--A1632---11------12-1213TIA211161111213-*2 S**6T34355333231222-2F1166322321C9BB9CEG9eEj4C547444PDF432-1XK84M4MfdP8111111111121112-1JIE6-6-42--5K8LRLe*8G----------111-742G483224P5SKKHh113iB*fkLQRS7555C311216R6*wq*z312633232322349151--7137676765635366332333476681433411------8M---------------1--12--12--2---112---------------------------------------------------------A439533343543328633-231A372-8341267A3531631132912-P-uA6691221256CA73225524734343233435-C7F7ED789D3-544636A566766A57AD48353469A4444444458843174----------1111211231-2112----63784437523GEEDBG78777AA7ECGA888EAA8C8511666CC62295847431N65323-1211111225BB9bg3M233215644419B3579L43E8IJl*3K345422222111411111116843844563A6RE7E8478998A69BADCAJABBAI1-1LC2411111133491433442322222-223222222222511331533489HL22322222222222222821422232-37777775797711271-1-3113175H26----1----------221221-1318P78899AC55IFKC986711111111113895666669869645689884541111--G29933DE21112111831-------------------------7435384A454*2E *******H*********************************************************************************************************************************************************************************************** ---------------------1---------------------------------1------------------------------------------------------------------------------------------------------------------M---- * b.69 7-bladed beta-propeller
[  16] NNLHRKLJMNLMMLNJULNONOKS*ijqhmrmTRWVSTebcgZVfPfpVdsopQdcaigfbTONOGKM nuxXwXWWYWZTTTZddZZ-ZiSSepZZZZZbkkkmkkvscjbnifYXZXVSchfWWTOOfhpVmanponWQQRRYUTTUdXbaYgcfZYZXSYXXTCDWgakagjnliQQQQQQQQQQQQQQZcbadfbfcdjemqrprNOPqbwnooppZegffZaYbbYdhbZnrxiVaSSVUUaUTTUcfXffTTSckioprospuvmrtsswurnmmjnrrukiirjniliikljxoj**zxxryswzy*tqheeedoaYZdeYYaaYgeXXfeababaSfijdcecaieaZZbbbbbcacbaZfhdeghfdgeggfcbaZZZZZZdlskpyrtrrq*uqwjhmuumgiesdniligicYdfjlchlefdeflkVZbhciwijwYcaWewp****gp**xw*pqprppqnoq*6wu*vw*t***fS************ypggbo*******woWWWWWWWWhihYcoqySSRSSRRROOOOQQQRQQQQQQQKQQQQQVigjeXu***********vuur******z*mx*******Waywu*vtvpzt**w*wvtmvgqtwbdcdcccljqr*xor*lsizzr**zx*a***y***********kiZYZWSUUWVVVSSSSSSSSTbaTYTaZ**zt*tqios*rurxrmkqrrsmswrpmvuV6agmgqRPMRRRy***u*t*******x**1*************yz**z******uwy**z*y**xzw*******wxywxv*jP************PQgkVUVVVkkkkom*t*lklornfmlbknhipjjhglffegf*t*****************ZZZXYXZZZlz********z****spwy*zytvznnkpTWuckkdigdSRSYSSTSVVbUOYNN-QORNTKKMNMLOIKRPKJKficegcfWedShVe ywUe***E*yyV*****************z********z*y****************w****xszussdwupy**uxTruruwwty**********zrzwt*x***Z*************************M*********************************v******************************** ---3-22------------3---33----1-----333-31111111---1---------1121221-2---------1---11---1------1----------1-111--1---------1---211-----1112-12------1-----1222-1-1-112---1-3251- * b.40 OB-fold
[  17] 6621319CABBDABDA2844433GJ99K8EHA333---2-1-29G47C34KAA-553665498A1-63 du*G*ZUbfffbTQ*****-**QQ****************H*w***bLLrdGrwvaN*34z**K*y****dHKKKLMKA4BXT44633GGPQ-Q88A--MxNZj*N*Te44444445558788DIGBLOMFGHIKrtscf666*H*pstddXNPSSIEHNOIUTJu*m*lDGBDDBCIDCCCpQgGF876KCWrptotptyUsrstomUObZdeoptAFEbSPQOQQRSQpgFQQQPQQQQQQQQQQSOOKQGMJDKQGFJDJXXFGPRD8DJDJFCDIIF5BCBFJIBAAAABA89895555555555555J997767889667QTEDDEEDIGHFGJEE3CEAM6DD4TA941OJ534C873177A74AI*1****w68878u****MFRqrhrmKLMMMIJHLJi1vw*wv*n*X**3***u**x***ww*xnupYknVPWZaZhONOOOOOOYUUTPRmY4455533344798BDE8CFA8BAAB32569kt*lJVoiXe*******u**q********j********9Myw*fhjTVykwl*ZQZlBF7FlI9988878EFLShiggOQD8796GD8894KMG9FCNBDedhc**9GA9B2776535514222212255768CCbWLaWinZsZMlelgforljihWkhnpYqy1-5MUNO-11---SSaaHVGNTUZNWWXRM-TNPRQPRPQRTVTPOMPOMUZcYZtnNPNMMNOOOMOPLPLMMlKJKMJNN91QOPPPQOOOOPN-12Z7A776cmjjAk*UdA99RBJ35556A678qsntqVsETUwe********zuzuzf*z*A776798779HMNgKKJJJZSURR*******vzxSNKN21D9llQShe11111111H37---26-9182334222385462111ECEDCDHCCD8sCS cUMT***-*xmP***************************************************t*hlmSthd*i*olUqlh*****Zee********u********5*************************D******************************************j*********************** --------------1--------1--------------------------------------------------------1--------1211-112-----2-1----------------------------1----1-------------------------------5341- * c.69 alpha/beta-Hydrolases
[  18] JJBAEEBAGKKJIGICNRLMMJHJTKLOMKXI97788FMIMKFFMDEMAAbNK6CECGA7DIGBA-89 GIUF*RNVbbfFKFmWVNM-NhFFU*NNNNMMqmpnt***G*V****MWncM***ML*44jaeN*d****aTPPPibXGFeZbAAB9ABBC94D342--2G756H9ACEAAAAAAACCCCCCC8C97AD9BVBG9lrrpq777obngkoccfTaRSJFHJKHRdJj*jyT9G9898AJ98A8tfVTTYa3ZJjvx*x*x**evz*yw**wqlip*w*NOauqcTbabaYZ**IQQRQRQQRSQQQQSTOPOVhbTUciWMPLPklJJjeILJMUOSSYVWVXQPQMSSTXWXYXXTVTVMMNNLOOOOONMNSQPUSOMMMTVrZi*bdabdhbSZUajdcLRRO*NQPFpRfGG**WaLNYbHGRONZBOTGDHsNOV9DA8E*x***WT***y*x*******y***1**********a9**************UNK**********gdggggggqyyUfqd*55444444443344443454333333343EDc*RI*********************************Li**************u*xNcUd*pHJHHHHHFGIg***l*Mggq*Tl*om*AgZWqMWZWSihWon*FfKJIHHLLLNHFCCAA9BAAAHXKBHQP***v*z*T*l******v*************7-IIYHm211222****v************-************************ow*************************a2************44BL58558QSRSMU***dddnWpGNQNMXPRc*****h*Rfe*z*****************EDFA9EGADU****************tsvspVXVFAAA43ooFFBACCCBC9C989K8I88F75-1151444111341A22333NbYPOXyVYVHZB4 21--22C-1---3FB56A6567676754455556645545554555759A6799666746443344342322444567BB44444433335365392433444655-JRb*o*j*ndSQRLQOMwuSiQ**b2mWzKTOQePQYILPPQPZNHrOoRP*FIWV*z*m*j**EIzI5da7t5B6ICcHI*6Q679Y88GG ----1------------------11-------------------------------------------------------------------------------------------------------------------------------1-------------1---6---- * c.94 Periplasmic binding protein-like II
[  19] IGBFAGeVYcceadeeHPQSWFGXnUScYgYSAECEBEGEECFBCBFCBEOOKCEIELIIIPKII4CB VdtZ*SFZbcmPKT*****-**DD****************S*v*qndMPWVF***cVn55***M*y****b57779999J*htKOAFFDCE96H98656CaKSR*RpZU77767776666666AYbUaXWWUaVWfccZd998la*vzqkmeUWccaYbYYYdjPjzt*mPVQRQRRZQQNSaaXOQFD6TWVffigidYkSifgfedbbZYVRhiiMTOZVedOMNNNLmnTVUUSUSWUSUUVUSUcZZUPFE9IJAAE79YYCCJLDGFHG8MNNKIIK8BBCGDBBBBCBBBBBBCDDDDDDDDEDDDCJIAAAHHHLFSQLZRQRTRPSQRLMJYVFNPJYLGG9I9EQP*xWhPJGTQRJJJHAFBSFo*stmDFDBEms***hYatkr*zWcfhYYfbce*3ut*u**x***y9**************aqVt**tuox*u*dcddddddifiacYZW77A88888886677777777777777777UZ**gEq**fu********yys********V********ES*v***qme*t*s**WYbVPMMjLIIHGGGGPPVdrXTy*TXZXWNZdWWV9MLLMOPMVIXbeY**LvHEF87999B7A6A6666666MEFHWUYZXWZulqMnYcRcfbbVilXUUXcZmkZpx529NTWU333333eYfdLYcabbcacYgaa-ababeZbZccbcbZbXbbdqusYYcgVZXUWWZXXYVVXYVVXzVWUUUXZG9QTSTTTTOTTTS789PFHFFFTSUSOxlt*IGFACDDBBB7FEEE*****VyRbUmj*************r***NGNEGKJHGOZTXeRRRRRcWWccgajltlnacdEEEEEENCllJJUU5555553593D33347-62A65666668B6665222CBACCEFEEEOR7F MODE*u*1*Yb7Wa************************************************fd*TXaLkPPmoyWWIYXWkmnvmVWV**********s******5o**********y*********w***4***zwu******l***o*tn*********k************r*********************** -----------------------1--------------1-----------------------------------------------------------------------------------------------------------------------------------8---- * c.3 FAD/NAD(P)-binding domain
[  20] --1112--1--1-11-2311--1v*fe*N***--c65279A7E**5**E****221113211111--6 v**B*54ACDG433KYVCD-Cr77JwCCCCCB*kllqp**M*k**LB49DC7pp*97A11RNx4*m****f333378854O5kKTSHJVVYD1M436--5pBSD****l222222222222228QGIPa8Jl**H*****yWc*e******Krrz*666886q*my***t242322242322*rXMHMMFTadffidiiknSqhonnjdijiifpsnXkgqTjeDDDDCD**9AA9A99999AAA99A8997B586886665556667875653433387843334664444444444444444454444456334333337F*kT*hffhgejSbaInZZPGHFEKM54eCBmf****n*PwaSMLUG862*X**xxp8DCCCiv***taj*****XYXXUXWUWWn-********t*e6*************vaObajg****awaCCCCCCCCcbZLK***22323111-----------------1-111Pf*TBV**Zv*******rsuj********U********6C******z******muq*nf****4444444HEs***h*******g*****4*****************hCIF39A88771-1111111koHSVOJ**lw*x*h*u******z*u******w****--4f***------eYwnKcSjddmkihhgb-XfkdlblcchXkhZdhdcddjbigMOEZOWSSVXWXXWVXVSVpSRKPOPWD-rIPPTRQMMSTS--8X9A8A7STSUnN*k*222212-12123123MNNKNBL5C8*******************322227222*Qfer*yy*wsvq**vt*****mqu776722*Q**y***11--1---M3611111-1111111111111112111OQHQOGNEGGA*5K OQCH*uR-*TWEZb*iqtnZZbccbWaRRORQSOPNKPNOMPPSRRilbajikuYieYabccRJJLMLDKLINMJKMEIKLLLLJLPNNLaWqTeNUTYVbYQifp6q************************C************z***y**y******lq*x**vh*x**en*pFvyS*NLNaj****v*pr*****w -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1- * d.110 Profilin-like
[  21] 5576667977777788865555578797989987877756877AA8AD7A99A67877C875566566 ADG8DCCCDDEABBC9AJJ-JD88BGJJJKLAJDCDFGKG9FDDBBCBCBBBECDC9B99BAE8CCGEEEB98AAD878ACBA76888BBFC69AA6237B8A8DAAAB777777777777779ADDEEBAAD7AFCCGH99B97IGFEJFO8A9AAA9A99DCCEHIKA888888888898ABC88797ACDFFFEFGHIEFGGIFGMEEEHCFFFCDAAABBbWaZaaF9EEEDEDFCEFFFEEDDDDDFDAD8GI9A8B8AB9AEFB99LAJA9A888989898A999999999999A99789888888977AAA88889FBBD9A9AAABCBDDCCCDDDBB7CAABCGCGEGCCCBBAAFDBG98779BBGCCAAAA8CBCEHGCBAEIGFDBABBBBB9BBA1BCFBCPJFAEB8DCBGCDGGIFDECBAABC9BCEEDBDCCCCCCCCCC99DADCH67666666556699AA79888788766667ABHB98888ABCCBBBC99999AEA999999ADCCBDA9ABA9C7987ABA8D8889798A8AA9B9BAAE87B998DFBB9CBBECABA7EDFECCIDFCCCCCDAE86676788777777776777889B8A9AAAABBAABA9AA99999BAAAA9BAAAAA617B889566666AAFDBBBCEEBCCCAEC-EBCEDDCCDDEBABBBBBBDGCDCEEABBBACBBAAAB9BAABBCCECABB97BBBBBBBABCBB679A88888AAAA9AB8A88888889988C8989889888798C99999BAAB8ABBA9ABB7777777779ACDBAAAAACBCBBCCEDEDECBBB99A66C999ACA877777777D7755555-55545545555554555557A87679767AB69 IJFF***4*VMB***qw*w*y*z**xt****w*y*ww*tzxv*yyz********v***y*z*ljokiiLkpolklstWqskmppkl**z***w****qv*o*s***A**o*****************************************************************Rmjj*ccXun*******Wf***** ---------------1-------------------------------------------------------------1--------------------1---------------------------------------------------------------------------- * b.34 SH3-like barrel
[  22] JH7A9AHFGGEGGGEFEDEFEABCXPNSQQUQ22944765665DG5DLCEFKH15C56BBCAA875DM OXwEcIJKOPNDEDUOMQR-QdDDXWQPQPQVbQRVVWaeDSGSMIHKKIFETQTHIJ55NOcFQOQVWWJ5888AA9879FNOLMJOWYZY2RHH4--GnTXN*XgMl77777777777777FHHEHGEFFHVDcbbWYBBDXN*hinhhYRRSSQPRTPPYbScu*zdMOMNNOOPLONMPLOKKFE9LTTTUTTTUVVQUWWVVWNOTSRXXUWQRSQSPRFFFFEEeNLKKKKKKLKKKKKJKJKKJLL9B6DF6C668CEAABC9B8HD7GGGGGKHDBDFEEEDDCEDDECDECDDDDDEEDDDDDGFF9AAFDEE7TMCRFFFEFFFDFFECDB6FFAQ9HFIT46BBOMFODCIGCBHGF8CDFQBh*moxDDDCDmh***ZXgpjpskSSTSSRTRTSm-r*zo**zydrw8pddgvtx**tsqp*ilgtfucUZYeiwUTUUUUUUXjeRWccZFFFEEEEEBBDMCCCCACCEABCCABBBBGnt*tFfonZ*******umoom****wtwufw***v***KU*****luhz**q*YhtulYZalTKMMMMMMXdhmrwZPSIHFNO8ULGGG5QRTSUSTSWihbg**TVLEGDBFFGGHF7A7777777MHCNYXVkjRcqk*Xqjennrqsasntoopmkluoo*52DYZPq654555bXXaQcWYZZYZeZbWY-ZYdbbZYYVYZZZYXYYYaklmddJLRidfgdfjgifglkgggfWZXXXXXM5YRSRSRRQUSSS67BcFGFGGTSRShdzXfKKKPJNFLKKLJFHOcZecdObQaWoXy***yz**m*x*xspgmOIJJJMIJIZZdamVVVXVhhqcdvtoltmmcfhQQOQJJTGffQRVV1111121184B12221-3423332333526233333IFCIKHHGHHJXFO skWZ***1***Rps*************xzxysw**zt*pzsxxvut****************viyeifNqnpprusuhrsjwyzoyfkk*******vpqokmw***E*************************9******************************************o*********************** ---2-2-1-----------3---11----------212-2--------1----------------------------------------1----1-1-----1-----------------------2------1----1---------------------1---1-----5431- * c.47 Thioredoxin fold
[  23] ------------------------64443226------------------------------------ --------------------------------------------1-------------------------------------1------------------------4-------------------------------1-------12----------------1-1------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------1---------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------1--------------------- 11--FA1-1---47L875556644535343333555232433333366559ADD577785551141123247-123434444333311178472365333334----913**********************4******************************************-673E-1111212161131-7893 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.13 Family A G protein-coupled receptor-like
[  24] 44-43377A999A9973A543339SAAE77NG88C426A79A99E9GE5CPKL3775568B756A118 Lm*7*99JMNKAABhVRVW-W*99o*WVWWWUsilpn***G*Z*WZRSC974bRUAAI44WRg9kOt***9A888676ADHAW8BC9AbchY3b88111B*IXP*d*Cs222222222222228865C7B779H8UVVUP212cC*jbwddSDJYYQJOMSMSeFbvr*c9L8ACABM975FMKGCCA76FBRSSSSSUTXGXUZVXWXQRPPUUZY9LIRECNTUUUTKd*CBBADAAAACBBBACBCA9EPDF9DGCCC8DJJ75HHDCCBABBCEDEDF999BCAA999AB9A999BCBBBBBBCBBBBGCAAA7AAAECLKPuQQRTSTUPQMRVSRAOTJgJGCEBPRB9qtIK9AC8B9A97G3FHKASwQQq1----at***bNZqpggdNOOQLPQLOMj-w**py*o*l*i1*tty********llNWNspfcTYYpdtFFFFFFFFSSQGCuRX-------------123--2------3-429LX*W4byqbm*******z**s********W********7L**mjgeXW*f*e*TZfaHOOQkJ6789AB8AEJUbdblUMNILKJTWJJO7SJKLGGMNLTWeW**JNH7C647679865B6656666BDB9COQmYSOYXkJcNPPhedcSUQeWTfXbUYefc1-3EN8U------ficZFhQcgfdccdcdb-gcbeecceddfbgeebfeT**yejTeMjehfdeifgjgelefhyXVQVWXUF-ZUWSXVUVWWVW--6F46456TaXWJP*ewA87DBF57776A8ACSQXSSIYBFDva********o****evvtE6535A846HYXVjTSTSSWebcfWabeaefTUVA9A943RTnmPPYY11111111H6A11111-113212-333134-21111AB8AABC9DA8bFV JOGL*x*-*yuB***************yxnvqr*tsv*x*y*zqqt****************nelSbVIbGCdZsMMGMMRiiidfNTP****z*****ukclv*z8*************************H******************************************N*********************** -----1-------------1---21--------------------------------------------1---------------------------------------------------------------------------------------------1------7-2-- * b.82 Double-stranded beta-helix
[  25] ----------------------------------------112-------B71--------------- --3-7-----1---------------------------------1--------1----------1-11131-111-----64------6571-543T--CLF126EB-1--------------*12222111141--------H-B14622111------------2274-----------------------32323633-333543----1-236---2---LZcSOA-1--------------------321--------77----1-----11131123231--1111111111-5544554535554-11---1111-2-6577687772711-443111873-4-121-318-1536-------11--F-----------2----------------------11111111---------11-------------------1-------------3-1-----------111DB-2412--1--1-3-----------1111111----1111------111--------I1-5---1--1-----11---------------2-2-------1-----1-11211-1----AE-211----------3----------1---111-116-211-111211311111162213--1--------------3---55-1---31-41114--1214-31--112--------2711322323324213-A9BC6AA2-156667533365--2-121129796--5-1-----------------------611111119286-68681423----------2112-----31122--22222222------171179aV--------K11------1--12--111----1-----------------3 RNAA***-***t***SabQiadbZcacUVTVSUUYSVWSSRUUTTUWWUWZZbVMQVUUdWYNcYOPP7ZSSzXwQTBSQM**mm*JKJ**qa***STUP*pR***B********************************************************************I****Yab******b********* --------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--1- * c.10 Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
[  26] UTNWOXWWWUUVWWVVPSZYYZXf*lp*ou**XWWZZYZZXYaXZSeZSYfkoaZfadYcXUWUVGYa ifpTobUZZZbYWXedeii-irNNtxiiiiigu***iu**RmiaeVfQTPPOemqaWeJJvlvRkg*kylgKNMMOLMKSiWlXYXXWddebPgUUC8BQgVmeiYbkZEDDDDDDDEEEEEEFXTRXUaXYWabZYYllRPQdepijnffZYWZZVTTUTTcccnigqZOQQNPPOSNQQRaWUYWQOKWaXcddefafebiefdhecXZZVbfeiWYbdaUUTSSSSSiiRQQQQQRQSTRRQQSUTTQTUNZMOOMQMNMbbQROOSPROMNXUXLLLKLMMLMMLONOMMNLLLONMMMMONOLONMNLNMNNNLLMMYdUZhfffefefZiaWeccZXWVVWWPLTPVTXrmjchVSZZPUTXZLTRashjWWqRONMOfavinicenmiplXXXXXXXXXXb8n*qjw*j*prgKjYXfjgjnjhbndgUXUfWaedbbiYaaaaaaaaaYbaZXrhnJJLJKJJJHHEDHGFHGHHGHGGGGIGIHOYgcfQamjWh*jjwmsqoopirry*utuuZss*zbxvuSVhgllffghZnlnfbdYlaUYWceQQVSSSSaaZhkdXu*qbmqkZohnnkQwjtbrdmcejjukmqk*aXUUTSPQSOSNPNNNNNNNYaRVReZggdboXjWgYbddZaZcfmdbaffZnjgpcL9KglgfJEDKKKncfchiaklmnkmkmki-klpmnlmkmmkmmkjlkkhjigcchhglhkhmlllljlkljgmfheegffhVKaXWXYaZVYYYZIJNZXYXXYXSRVXcogkQQNWRUNPNLNONNReZddbVcaabsXtsqvhkohlrjsndgehRPONORPOPSbZcnabbbbgeZfhaZbXZXXVWXTSSSPObPRTQQSSGGGGGFGFMGJEEECG-HGGFIFFFFFGGIFHGFFFRROTUUSSSTSdVW YZKKpsi-*VTMacwZdjgcefhminjiiifgfjiecgeeafffefhhhjmpmmdgfkfdffeefcacNgeafdfhePifbeefffcefdvYdddhcbbaWdc*u*Gm*i*u*kqqzigiZgkg**k*q***5*u*Zjef*dqrfbmbfSmbV*hgjfs***q*uoc*dn*rx*llsvs*nnkuu****i**lq*ouos ----11-------1-----3---21-----1----11----1-------------------------------------------------------------------------------1-----------------------1----1-------------------52--- * c.26 Adenine nucleotide alpha hydrolase-like
[  27] 77C7A8BDBABBCCBCA6D8A99CJBCEHFGH55844577776AC78975A674694899D8889288 IKTFP88FCCD698OLLMN-MT77ShMMLMMMYYYYSMsrINLQABBB9887JEIF9A44MHYAKLWTVPD6777877569DIACCCEDEB96B993119EABEJCKDD566666666666669BAABBF9BBHCIHHGGCACDLROJNMMHFIFFEFFFDEJKFGLISHBBBABBBBAAABEDDCCHG6C8BEEFEFFDGCGGGFGGDBCC8DFFEADBC778888888EE8cdbYVRYTTXUdSTD88A985556655545664566555575556757E9D965555555555555EEDCEDECCCE8A6555555557DTJ8GEEEFDFFFDHEFGG8776F7EABJAAFMJJMRUODQJLBBAEB65J9AKGHFA9AAALVihvGCLRPNWNFEFFFFFEFEJ1VVYSTiUbNVM8TOOPNMdRONcgWZEFDNQOSPRSQRcGGGGGGGGTHIAINFG99999999788877777777777777777FFOVF8MYRPQfhihhgSOOONlliqRRRRIVmf*gpofDIWWPeaJMJWRfQgdKRSHKHHKKEEFEEEECAHMbUCMOCMDDBCJDBCC3ILJDNGIUMIHGIMLKYA9A98AAAA99798888887AF9ABIILKJIGDNCJDKLPNNMIMMMLLLMMJHKKS7-7CJIG585777JJGIGGENLMKNJJFOM-MNKQLJIOLNLINNMMMNLOQQIKJKHHIIIIIJHIIHIIIIHQKJIJJKLB5IIHIKIIIIIJI778DAA9AACDBCOELONDCDFCEBBBAABCCCLKLLNHKEIFUCYYZZWZYUWabYYKPPPA99999999GHJIKFFGGGKJGHHEEIKKKKGGGAAAACCD8CB88993333333364644344-2242222222242221222GEEGFACAAADG6A bWTY***-**uO*y*vqqooqssopmqpoitpsnplglpphqonqqrpooupstklpmloppkdgbedLbjZfgbfhSchebcfZclkkr**qwt*vkkjkoj***D*************************c******************************************e****wsn******r**w****** -----------------------1-----------------------------------------------------------------------------------1-----1-------------------------------1------------------------2---- * d.15 beta-Grasp (ubiquitin-like)
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bW-aGD*****************************************************************85A9*AC869ZVgvFlG58AEFG9 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.7 Spectrin repeat-like
[  29] LLD8CBGIJIHIIIIG8MGHGEEINMMPEIQLJFFEHHGHFFIRSJJQENNPKCKLIHJIMIGFP-GJ QovO*PJLOONIOIpcaab-abLLkwbWbbbagfffim**OjjibfROKRRKnhiVPe77timM*c****SJKLLNRNAHNTSIEHHDcZUUCcIJ444IiSedsUmTe8888888A9BAAAACKMLOMLINNJIehhhcA9AcXXSVRRRXLNQRQRPRQPOSORgZkWRTPPPPQSROQQWTVNNEDHTTknnqnqooqernpnsnemkjeimrtacYiYPSRRRSRP*kLSSRSRSRSSSSSSQWQPRTKDCBGJBL6D8PRIIIK9G7EMBHEHAAB9788DHGCEEEFCECCCC8888888889888GFHIGHFFFDKmTalgggghiiRePRiggOOOMcPVCIaTROKcaOSQMJSMQTQTKJKHjHTfZZb99999XZ*sxUVRnbdgbVYXbXWYTWWm4fhsej*apk*V9qhhnrt*vo*v*jeQaRfinjijmom*WWWWWWWWWccRPiYjA998988888355555555555555A7C8FORjORozpgp*******y**w********b****utxtDJihqfhjXT*hrfxnTYYNONQlUIIGIIIIOLPUZWKYZSTKUTPbaaYUEdaYcYVcWSYacZnsSVTIHGDKIHHJFCKCCCCCCCNOFGJLMgZPTSQgPWTWZbWYXYRYVUVWSWaZVZfA29TROM664656mgmfYkifggifiiigf-ggdgifhhigghgfefffhtztmtmuYidghhhihhjgghghezYXXcdbbM9habcgfbegfgf88BLHJHIINMMMSQkYoKKLIHLCHHFEHGFLWaYeWOSLSOeSzyzy**y*i***wdnooQILHIKJIIJfWVhVZZZZfjhgfWXXaXabTWUDEEEFDWKXXRRTV33333333K6722222-2332322222343232111EHLIHGKGHGPWQP BA46cii-vOH8Xcfivxmxy*u****oopnonvurnsrqpqpkijups*****zwqsllkjdehQZhUaWSgZgdZKabcdbeakSTWm*fvkogkafgekdooq5j*n*y*oz**qinqqir**m*u**y3*v*hmmpwkktjgipommif*rmjmpx**h***owet*i**qgtql*babwt****s**to*s*x* --------------1--------------------1--------------------------------------------------------------------------------------------------------------------------------------112-- * c.67 PLP-dependent transferase-like
[  30] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111-111111111----------------------------------------------------------------------------------------------------- HFHL***-*RM9nl*dfmdgeefdfadhfcgcgZbcXgZdYfgijgchfdfcdlbafadcfefZaaWaETbTWUYdeObfYaaaUZabcj*jftoykgkhVfg***8********************************************************************ANHN*HGEKJ*pz*l*dUX***** ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.55 PH domain-like barrel
[  31] 551-1331------1-53534231233521531411-------43113115231----1-31115-11 2211211211111112211-121122111111211111431222121321112231211112111112111211131111243111112221111111-1212142431111111122222224113221112113111211125398443654111121114554656F111111121111222221212413432413643543315244311155A414112333457412232231333322322221311124134-54344541432113211142444111111112112122311323332224311222111473232311312332232331445912223314245322323613329111245122312311312221214111122212222224-23622744112121112131122222121342342322211111111211242111111111111111111111111111111423212111111211221121132225113311125231111261114221511112221111111111111212212221113112412211211321212545376111221112111111121111122121111322352121423432222322223232222-1221422222222332424444444245-4445444445444444445333321223334333344243344344455542222122222122222111111111122142211122213122222211111-211112222112221111121111111111111111322222332333312322121131311111111111235133311155111--191111111212Z11---52221566651511 bKKL***1***wyk*kx*xw****st***pwtvstwp*v*rvxz*squs*****n**pvwlojeaadhKXilfYWpmWnqfeeYTVXbfmxkx**mnjplVmk***7*sv*****************************************************************L**l*nkk*********ky****e ---2---------------1-----1---------112-2-------------------11----------1--1-1---------------------1--1-------11-1----------------1--1---------------1--------------1------3-2-- * h.1 Parallel coiled-coil
[  32] 11111111111111111111121G*HHWDncd12H31244446yz5X*AavUc12122321111117D d**D*CBCEEEA79IQQHJ-Ha77QcHHHHHGiVYXkhngK*o**fIJITRJPRVEFI44eewE*cr***lDAAAIBBBHZHP68BGD***r3*BA733D*HcV***v*555555555555556GC9IJADNQeB*****UHL*C*w**ppRTUJK899EDCeoQp***i7987767B6786gWODD9A8OShqqypywx*Z*u***ynpifch***LYXuRaUMKMLKN**HLLKLKKIKKJKLKKHKKKFKBD9IJA887BIHABIIDBB9E8ACBLNLJGIJJIIGGGFGGHGGGGDFEEEFFEFGFEEHDGDD9DCEFO*gg*ggfmmllihfhtonRWaT*bgEGUZmZD**sYQNGMHJJDMT9BB*ap*xxwCDDDEbg***lTW**x**NNMNMNLLMMU-********Xwj8pqqvxql**yrpnqbTeXPdmknmUjRLLLLLLLLLRRKM*vx6666666666k*77AA78987877865566NbrMHQUQNX*uz****fijexw**oqqsQp***y***6Atwn*z*cc*****QfnxZcXXuS7889988IISm**q**kYW*vJ*****7*******d*******U*eDGEA999979676666666feDIYIIpdNxl*yVyhSqkorlYkjopnfmoiph**3-9PUXW332333bWYYSYRYaacYccdXY-ZaXYZabXXYZbYTWYWWYbcdYXOMMaYYUXaZYYaaYaZUagUTQTSTXE2aQUTUXVQTUUT11AOBCBBBHIHHOa*Pu99A98948797878DOOMMPCMHOHih********w********877757867PZfetmnmonmusvx*******mqsIIGI55*C**aeut88788888E4511112-2222222222223322222EJBDDDDCDCB*9T 9B48WZG2SRA7CCfQTXVPQQPQMPLFFDFGGEEEGJGIFGHEFFUWKMTTSbOOKJJLLLDCBAB98E99CCB9A7AAA9AACD888HSFTJMGJIIGLGDOPU4QlllVXRPVZMHPLLRLesNkJ**U2qWlKNOMUKNTJGNNKKPHFYLSOMhGPXLONq588FMGCUGCPPI*CDEFI*Uf*WnpSKqJGHN ---21--------------2---------------222-2------------------------------------------------------------------------------1---------------------------------------------1-----1116- * d.122 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
[  33] -------1------11--11111---------------1-11-11-------------1-11------ --------------------------------------------------------------------11--------------------------A--------------------------2----------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------1-----------------------1---------1-----22------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------1-1--23------111-------------------------------------------------------------------------------------------------------1----------------------------------- qghk***3***********q***rzyv**z*q********t**vvw****************soldehQjhklmjfgKejhjmjiiquw*******tiosj*q***N*************************q******************************************j*********************** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------5155- * g.44 RING/U-box
[  34] -------------2--2-11-----------------1-------------22---------11---- 15K-1113444---1----------1-------2-21221-1--2411---222211-------13-2331----------4---4--2-------*---71-46-713--------------7--1-1--------------5-E432--22211--1---22135435------------313----611-5555543515234431-----555---4-31----1-54--------------------1----------11-----------------------------------------------2------------22-------1-22-------1-1----1--------11-------52A-8211------221311-2---------------1-11111112-11-5112--213-2122--2-12-----12222222221222241-878BBAAB55ep45UU55Q533662N6f*-11511322211457515111122231111117j63333-1226122334422223352333--11211112212365528--2---2----2171623-1----7-2382223222222-E-------1--2111----31--12-5312-233-3---322125--2-131-------2-5-122331211141-412221-1214131111122223512------1----------22344--41-111111111111----7JDBAMPHL3171---------------13444342---2133332614-12122223111-13111--1111111111-2195696C95553343--8*HH96HF22222232A61------------------------------------23- KGIL***-*dd*uauYo*p**********uxqw*****y*xy*ztu************f***MKKIIHAIJNJFGJLCJJIIIIHHGFFNrlo*V*FHIGEGIjk*2*************************u******************************************E*****p**p************** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------*C-E- * d.211 beta-hairpin-alpha-hairpin repeat
[  35] BB548788A8889A8C7B99996ASJJUHLOH77634379797BEBKE5AZZX5AC9BB9ABC96147 CYhD*FDLLLLBCCcPOLN-LO88XdLLMLLORPPPhrmhDoVlx*giTpjCvopibg22**iI*b****K9IIIKJJA4GGS44433MJTO4R89211FrJQYrGdBQ111111111111119D88AAB798DDUTTbYFFG*D*KURUSDABGHB9A766GLCdZdnI696766986686tXxFF643E9f********m******rwkkmp***HJQ*jtxXWVWVU**efcecebYdeddddecYXkjYFO9YZBEJBGXXIHUWGKJNPKRVVYYYPOOOaLLSSSROQTQRRRGIFGHGHGGGGFGfPPNLINNNI9ficsbZaffqgUfZFOLKDQTMtBIEHVHM73tnL78BAE6383CA6JGO7Pggff33225YR*rxWOPdcaYhNNOONLOLOMo-XTeXfuUkd*T3*yy***x***oyeVTeQSqfZRYYUfgDDDDDDDDUPQCINeS1111111111-5427714822133111134QSWUAWURHWt****zofghdllqnonosQh*rkWWiT9CVVSQLXHHZIRQdIGQOEH7D*I7988888FDOMNLFWbJGAJJDNOHDK3JHGFD6EEJNMTP*zLMA3692898975282222222AC549JIunKTQVpRdLOhnqolnVTibcgfddmicu--4IJHR1--111YngeJlcRTTPSQTTRR-SPTTUUSSTQTUVRTRRSOx*uYZacTUQTVTSVSSRTZVVVW*QNNPNOPG-YQQQPQOPQOQP--8K8A789OjVcBG*PrAAAB7A54345554AWSWcXNNADGRLmonnq**vdhgjdRnvuC55456555Abchlfdfae*pl*tjlRSQTTQRUCAAA11KKGGBBLM33323222P3E----2-1---21----1-71-12227I655454436OGK HBCD*vQ2vOMIRSYrn*gtw*vypusjjiohnikfntmqiqsbbdwo******fiqdghgecOMHLLGOJKNINMKFQNLNOQOPSPRb*bndliOQTSZPVwdhCW*w*t*nlwmZfYfbkb**d*d**y3*q*UhbYqWakfQcUjZkPR*dZQfzeegS*eiO*mxvpzqnOnof*ZbbiV*ba*uvjmfrdckb --------------1--------------------------1111---1-------1-1-------21-1----------------1--------------1----------------1-------1-----------------------------------1---1---41--- * d.108 Acyl-CoA N-acyltransferases (Nat)
[  36] EE9698LPWZWVOXQOFJJHKINHTIJOLOCIYfN89D9DEBAHNFPNFPPWX9NKMNLJLLFKB29F bT*NkFCMLLIAAAJILNO-OPDDRPQQQQQMSRPRPTVUQlkgZTRHGQMMTWWNCEAATPTAbOUhhfNFKNNIFIIDUJUCIHMKw*ut8wHJ5--HgVaSec*JY44444444444444OPMPPVQSVWaPlnnvs6BBbNhps*rtnHJQQcRTJKQLZUj**ywKKGBGKGQPBHLEJHDDGB9IERXSZRbcTXRWTWaZWOLKKRUWVQBMFDGCHBBBEABViCBCBBBBBBBBBBBAC999EQG69GKCCC9GJK89JMBECEBFHGQNMOBDDDFCCIEFPCHMNCLBAAAAAAAA8AAAALIIDBEHHI9LHDnYPPPMPPSUQVHLPPEMGGKBNA9JYPIFRPRZRJGFHHAE9IFGJLGbUMMU45555aPUVTSMKPOMQNFFGIFGIHIHU-riprmvnvQlH6gYYZfeighigfWRdMOQRKUVTVQRLRRRRRRRRaXYUYhbS2211111111117AAA69B7878875264BEKWFJICCCIfegcgcdTWWUUUhrffegMdcflTTOPEIOTLNMNJDGLMLXGOOPPIMNKJBDACDDBNLPPUKCXXaIKhmStakfkJsmtjfbwVeaaWcYcUXBAFB9MILLQMEJCDDEDCCDAACMOMOLLYUTIEWBMGLILEHKMKIFHGHKIJNL2-9LNGM21-222MOKLFNLNOORNTRQQN-NROOVLNOSNOQRQMNQPRNJNNLHNGRFMPQQNTTQMOTPSMMJJKJIMIE6MHIFIHHFIIIJ23C9BBABBBCCBWEYJEGCDCEEDFFIEDCFIDBFDC9JFF9ZQQNLNYgdNMQMZXIdcaMEFFFDFFEFVMJKBBABBFJJDHOPTTQTTLMOEEEDC6XXWWZZYX44444444G33----1-4132744---7C6511111BEEGEDAAFBUrRa 86EFQPs-SF99jkpiiiYVbccifcXXWTTTTTSSUbUXTXVQRQegbdoqrudjZcXZZZTRaRSTFYcSXSdWXMWYSXZaXbMMOZyWiZYeRPQRXXV***8m*S**********************9************u***n***************vc*k**x**qRgsV*SONkk****i**ib***** ---1----------4--------3-----1--------2------------1-1-------------------------------------212-1------2-----------------------1-------------------------------------------8521- * c.68 Nucleotide-diphospho-sugar transferases
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s1L893fh*ORMJOOMMPQOOQQPQNQLLJJJFKBJLPMMOHQOQOUSJKRJQLOPOLNGGH8LICKFLMMELOFLLLLLUPLRrSRZYYQQTTJRa***4*jG**********************W******************************************ENMO*IDDcE****N*c46CHFEG 1-111--------------1-----11---1111-111-1-------------------------------------------------------------------------------------------------1-111------------222-------------1---- * g.39 Glucocorticoid receptor-like (DNA-binding domain)
[  38] ------------------------21112-121-1112111111-1-2--221----1---------- --1-3--1--------------------------------------------------------3-22431----------1----------------------1-----------------------1---1------------24233321111213322-1111122-2---1-2----1----------------11-11-1-1-------11-----------------------------------------------------------------------------------------------------------------1-1------------------------2---------------195442-----12422--22123311111111111-12214312322-311232175532-143344-313323211111111----1331------------------------------32632111--111-1------111-------11-2224-1112-2323312--1---1327-2---------2111123-1--11442251---3-2-12----13-511------------------11-------13-13-5C2------12---------11---2-----------------11--------1---------1---------------------------------------------------------1-----------5---------------------------121-21113--1211-122111-111111--------------6565754566------2-11--------------------------------------------1------11- *fdo***-***Urt*lliYcZaUeZZaWWWWWXVVSTXSUUVYUUUeaYaYaXhQRcYWWTTPLOLMKHLMIKNMNMBKLMMMNKLSRSZvWlebcVUSQLaT***8*************************b******************************************D****jphpj****g**z****** ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.39 EF Hand-like
[  39] ---1---14444243-291----11--2-91-----2------2-211-4282--2-63-311-122- 56H2e32133312122233-31--333333317212-22344164861497-BA8--4--5712J2ADLF353334542-3-------EEbC-7-----9E1G5LAH26-------------------1-783--899AB123W235131163----------4--3424------------4--1167132733333222-342333789948432-11-424-----12K22222221222222212211327-44-22-155--3321134-4341111333433444554454541111111111111434111444542-8944437744539211-893D251-3345---4-114---21-4--41-Y9668-----3-612---22-21------------4432357333--833454455445--4212--43852--11111111-332-H---------------------------------492111---3222333111111-31211-138221211-113222--3-122311-121-2----------2--22B-------4-----11163172-11213P------------------------33---23411R71B231333483-444413584-7------2------1223-33111212342--1-1232-13112221-32-56544221-3--------------5--11111--1-----------------------11-B11111111-----1--1----------4O4444453252111-5541111-1111-522-43333--3112198889343------72AA111111111111214----2-----------1-----1112---191559-J72 9758VX*1*Wf2LMJZYwkalsfoimmJJHIIIHHFIJIJHGIHHHokgruz**moqtmaabEEJBDCCDEHECDGHBFFFFEFFEDDFwxdYxnmOKNGNTTPOY2k*z**********************s******************************************4KRJsCDBRH****i**KE***** -----5----------1-------2-----------1--------------------------------1--------------------------------------------4--------------------------------------------------------11-- * b.29 Concanavalin A-like lectins/glucanases
[  40] 6665665545455555A5668667HDDHIJJI8AB555586758A6DC9ADDCE77678665666576 CDUBRDDFFFGDECHHEDD-DJ99FIDDDDDDOIKKLJQRBGILEFEEFDD9JHHDCD99KHIDIGKIIIDBAAABFEDBCFG67AAACCFE8M89C-1BHCGAFDEGCAAAAAAAAAAAAAAFDCDFECFEGAGEGGFEBCEMCGFGFBAB9978756556888BDDH9555655557656FJE9ADDAEDIKLKLLJKLHLMKKKLHFGGHHJJKJHGLGHFGFFFGFJGEJJJIJIHJJJJJIJGGGFIDDEBDDBDCBCEEBBCDDECDFCCCDCBBDBBCCAACCCBDCCCCCCCCCCCCCCCBCDCCBCCCCDCCCCKDDHHGFGGGHHHGDDHHFFEFDDIA9HEEEJDCJJDGFHFDDDFDCBAG9OKHIGBCCCCIGLHHNGFHGGIGCCDDCCDCDDI-RQRNUPNSLVE9IIHLIGJMKIJJHLEEEIHEGJGGFHHIIIIIIIIRJIHIFHHBBBAA9998888AABBAAAAAAAAABACA6FHGGEFEDEIMKMJMLIGGGGNMLRIIJIEILOIFGMJACKJGGIGDEGJJHEDJHJGGFGIDHEHIIHIFFNLEFBFMHBBEGAGCEDDALIMGGHLFIJGMHLPHG868576666655555555558897ALJIIJHJFEEGHKIKJKJIHJLIIKHJJILJI71FHDDI565666KJJJGJILLLKLMLMLL-KLLMMLLLKLKKMLLLLLJKNMOJRJJJJIIJIJJIIJIJHIJKKIIKKKIF5KJJJIJJJJIII66BDCFDCFCCCCFFIICGEGEFEFEFFCDFEEFFFGFDFEEEKGKLNKKNLNMMKLNKPLMCCCCCCCCCDHHHJGGGGGHHHHGKJLJQJKIIJGGGG66CBCCCDDD66666666B9E55257-76757665556765775559CABBAA999CNCA IFEFwl*2pGLBIEVHKROPQQOLMLLNNMNMMOOMKMJMIKMLKLORNNRLOPMPPMNQQQHIJJKJ9FLKIHGHKDHILLKLGHKLKNTHKUK*NNPJDRNXVgBq*h**********************c**************************z******p****i**rGX*Q*RRNRIlbbrSiiHKhtcgR ---1-1-------------1---------1-----111-1--------1-1----------111------------------------------1-----------------------------------------------------------------2-------1-4-1-- * a.60 SAM domain-like
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asqz-***Lvz*pmwnlnnnnlfkooimgmklmjnjlfmlllmoslnnlopgnoilmilshkffhSfhdhhjdgRdfeghhgjihjh*smtmxlihjdpj***Hu*m**********************9***x********s***v**q************zj****r**vg*************t****y**** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-12- * a.2 Long alpha-hairpin
[  42] 778788898888888897778777AAABBEAA788BBBBBBBE7BB88AA9B9BDFBDEGC88997CC FKGFZIEKMMMFFGUOOLM-LSBBRZLLLLLNRWVWbbwmILHRIKGJGHGBRNOIHHBBQMMDQMSURTGCEEEDCCCCEFEFFFFEJIKJCHGG856IHEHJKEKIGBBBBBBBBBBBBBBDHHHHIGIIHFJEFFCEFFFGEIFHGGGECDEEDDDDDDFFEFFFFFDDDDDDDDDDDDEEGCCDDBDEIFFFFFFFFDFGFFFGIFHHGIFFFCFFHHEFBBBBBBFJEFEEEEEEEEEEFEBFEEEGCCEAAAAFBABFDEEBACCDDEBDBDEDDAAAACBBFFFGIGFGGFFA9AAAAAABBA9ACCEBBBEBCAGJFNQMLMMLMMOKOHIIIJNNLHJHGEDGHIGIIJJGGHGGHIIGEDEFFEKHHHGHEEEEJLROTGFJOKKPMGGHHGHHFHHK6NNTLNWLSIJFEOLLHHHKMMKOSSQEGFGLQIHJIGIMIIIIIIIIMHHEGIJHEEEDDDDDCC8899AA999999999DDDDAFGMGFLUQNTVRSYSWSPPQRTTVaQQQQJReUdVebYDHRPNROIMJVOQLVVIPMKMHKMIIJLJJJJIJGPURFJJJJKJLGJKJJJELLLJJKNKKLKNLPPILDCCCCCCDCCBBBBBBBBBBDBCCCLLRQPLOLNIQPOQPQQRKPSRRRPPNPQPRTD4DKLGKEC9FFFONLMJNNPOONPNNNPP-OPOQPNNPOPONPOOPOOQUUUNPOOMPOPPOPPOPPNPPPPOQOOOMNNNKAONONOOONOOOODDEIEEEEEHIIIMKONQJIJJGKFGGFEGFFFPQONRMNGJJSLVVVWUVRPQYbYXPLMLFEEDDEEDEGNRQSMMMMMPSQSSNONNNNNJKJHHHHFEIEIIFHFF88888888D9B67679-6696677666698766777FDDDDEBEFEFHDF UVDFbcW4*tiFcYljgjfhljjurpkddafaceidafbdedcddejhgssuyzdolgfgfhfacVYXHbWUcWaZdIWcVhihbnZdbi*hgbjeZWaZWWWpiwCY*v*j*horxceiZeug**Y*b**w3***SehS*am*iUicdQvbP*htfhic**UihjQwZX*pflfcjik*jgdfm****j**ln*zwzi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.43 Reductase/isomerase/elongation factor common domain
[  43] DDBEACFFFFFFFFFFAEDDECDGFEFGIIHGGGEEEFEEEEEEGFJHIILLLEEGEFIGFEEEAACC LLNEPHIHIIIHKGGJKJL-JIEEMKJJJJJJIIIIMIJJILKKIIIHIHHGJIJIHKDDJIKJNJJOQOJIJKKKKJECFHHHGIHJONNMGMJJFAAJNLMMOLNILEEEEEEEEEEDDEEGJIIJIIIIJJKQPQQQFGGOKILKJKKJIIJJIHGHHGKKJIJJLLFHFFGFFHFFFGKKJKKMMHIJMKKKKKKKLJKKKKKKMMLLKLKKKNLKJMKIMMMMMMNSDJIIIIIHIIHIJIGJIIGJKGHEIIEJGFFJJGGJJGHFFJEJIKIHHHIIIJKKGHHIIIGIIHGFFFFGGGGGHGFGLIIHHJKHIHKVKRPOOOOOMOLNNOMNNMLLLKJMFFLJKNJPOPOMNRMLMKKKJEJONKLJIILGFFFFIMMLLKKIKKKKKIJJJIJIJJJK5OOPOPOOQKMKIJKKKKLLJKLLLKMIHJIKJJJKJKJKKKKKKKKKKKKKMNLLDDCDDDDDBCCDFFGGFGHFFFFFFDBCDDHIIGGMMMKMLNNNNLNPOPOLLNSQQQQPPOONMNMLFGLNLOOKLMKKMOOKKKLKQPPKJIIJJJJJIJIMLLNOSMPMPOKMPOOOKOQPMNNPOPLONMRSMLHIHIIJJKIKIGIGGFGGGGHHGHIJKNOPLMONLOOOQPQPQPPQPPPPRPQQPQRE3JLLKKEDCDDEOONNOONNNNNMOONNO-NNKNOONNNNNNNLMNNMOOPPNMOPNOOOOMMOMMNONPNOOPNNLMMMMMBPNOOOPPNOOPOEELKIIIJJLLLLRLRLNNMNNLNGNNNKLKLNLLLJKJLLLLLLOOOOOLMMMNNOMMLMMOIIJHKIIINOPPPPPPQPPQOSQNNMMMMMMMMKKKKFFMLJJJJLLIIIIIJIJJEG88888-88878A7788789789999GFJFFJGJJJGLIM NPBHXWb7*kTFWWXRVVUSTTTRVSTTSPURTTURQYTTQSTTTTTUUUWUWTRTUVWTTTURTUUTJPSTTRQSXJWTTNPQQPVUUQmWVUVcVTVVQYTegoEY*b*ilaaiiXTaaXgXx*Z*Z**o2***VYYZuWYkUNaXSTZVS*afXWbXy*UwX*RaRavqojZfbei*jmhZb*y**V**fjrjgda ---11--------------1---------------111-1----------------------------------------------------------------------------------------------------------------------------------211-- * d.14 Ribosomal protein S5 domain 2-like
[  44] 8774A4CCBBBBBFECA8AD9877OFGGFFME99D55765555797B779JIE5CDDGGHF8878134 JLR8aGFNLLPGFELIHPP-PcAAVPPPOPQJZTUYSZXY8RNRNOLDMLLFPNVDCL44VUMIYLgedXJFFFFGDDD9HFF6ACA9OPLP4OBA-118N9IETHNGJ33333333443333BGGBHFIDDGDGACCII677NGVJKPEEEAAJJCCC9BDJGEKUSWE9C98A77B8899JJGBC99BCEOSSZRYWXYKYUWWXWOLLLMMVXUHFEPJLMROOPOMPZGKKJLHJIJKKKKJJKLIJMNMMDPOEDKFMXWCCLONHJGECORTPMNSJIINNMGHGJJHGIHGGGGGGGIGHGHGGHMPOOOIMMMT8IEWaFIFIJKHPINEOIHBILELBBI9JHL9AFCDBB9EA88EAE96BLD6GOGGM22222NMWPdMDJLJKJKFFFHEGHFHHQ-PRKLXWQPKUM2WKKQSOTWTRQSISHKCPLKHIHHGEHFFFFFFFFGJGADFHJ1111111111111234111111111111159FDG8FLLJMYUVVUUSNOPOVUXXPNPSMSZTaKQOR8CSTMIMLRLMPOLSFKIODIFGSCBCBCDCCAFGLIIFCLBABFEBHEFEG7DEECFFCJHFGMGQaDIC7797ECCCCB978979988A98AFGKSRPKJIDCFGVHJGGIHMGLJIMGFGGNGJ2-7IFDI221223UUSOPUSSSTSSRSVSQ-TTSSTTUSRTTSSQRSQPUUXYNRKKKXTWTVXWWUUVVXVUVROQMOOPPF1ROONPOONPPQP343CBBAB9GGHIHGLJMEEEGGH8CCBDBABIJHJLJEHCFBLGTUVWNUQWLNQQNJVaVBBAA8BB8BHEGHOKKKKKPQTOONLJKKKIIII666697FLDCAADC5655555585D47536-9667C746667895685556CB888D898BNHC KKHHYRT-*eWITTaadihcdeeljkgXWXXYYaaZTbaWdVVUSTXdbflqouWbcYacZaSUTPTQDQVSTOSWVLWbQUSSRTWSTV*YdTceQTUOQdQrlwCT*j*****s*tojijhr**p*t**r7*r*jmio*ijykUnmnVlgd*rlomudv*enZbfxSf*ZskWX**l*ppm*w****h**hp**y** --13----------1----4---1-----1-----22212------------------------------------------------------1-------1-----------------------1------------------------------11-----------3---- * c.108 HAD-like
[  45] 3421-1333444534C-234111362286223--1---2---14a1D876ekH-23-5113434--*8 Vr*7e45555544557756-5H22CG555556LGGG6CNJ7K8OGN965665CFE66522EHBAUKTTUV423334221131411422ia**1b6531-Fe6Hf*a*J*22222223222222532B466222C5MUUKW153jDKFLLGH878554668458C4gMPTI352332252333EC9363235283333344424434544599455452723645222232DI233333333333333233332232333223222222222222322233323332224555544545533333333333332222222222877ACCCBBCBC6CAC2756DD9A6I11B953235723435323247122j3*GGGG33333CAXKL674997896666666566A-JIIFIEJJEEE3FEE8FAHHGCFK75AGGD8ACBDDD9A777777778BBB3795222113311122334443533333321224AAKG93A64COEEEFMHGKKIGFIOMKKJ9ELHWDAG755CCEK8G66GCABOG55B6B6873332222396B7C5NZ7E34622782232DOD58DR44KHFK**5O323325555443243333334232244444NANKDOJ7PKHJMMKHKKIIJJJMGNQ1-3C776111111889A4687889798A961866A797B8689977777689979AE6898A9998878BABA97655657632644455545555223E66666445465U8D544644344334447ABA6B67463HOHIFHLFNMIEEEEGJGN34444444455A96CCCCC8BACCKIXbcbXUSXA7773367HHFFRP34323323A5311112-222223222222222322364774365546*9K GK6AhY*1oOcJGFbPVbVPTUFgTiQGFHGHJGDHEFBF9CHCDCbUNYkepwUUndNTQQCA889749A6967BA6BA888A76599QQGVPQaEDDFBKCkqc4U************************Z*****************************************uTfsW*RWUgd****V**YYtcTc* ---------------------2-------------------------------------------------------------------------------------------------------------------------------------------------1--5-21- * b.68 6-bladed beta-propeller
[  46] 11211-22333333322222222133333422112111111111112112222111111111112-24 ADN5733433333355555-55555555555546665575566655334443445233224443447565411111113122657756774525665--35237A5876222222222233333444544444A4666B933376867A6666655666666566C87A8464444464455995443416686666666776666785587787675675755444444783333333333333333333333434433333443344442333333333233332233333333333333333332333343333333336447454555555558566666674622653656776655776666621399SAAAB6777798DBEC97B99B877777777777-CCABCBB97C73D777EDBDBB797799A74698995686666666658877C7633333333333334344454344443333356A7466666AAACAA87888BB9ABBBBBBDC9888855988A87868688757995A777755555557788C7974435675B96673ABC7C7978HHGHOR773455355555554455454554443996768698888587777777777786777874-4A88A22-22287897778888999989-8898889888898998998888886657777777777777777777865777477777777777744794342266669995554555555553555577777786766755556555655656555---------56666666667666689B9A99888666622C477AA9944454555653-------------------------33332433449IC6 332221*1I88-89B54432334333344333333233232333333346555C2444444462333224334343333311134468623242222222343BCE1O*-*****************************************************************8IFE*BB9EBMQaR4MHo*y***w ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * b.36 PDZ domain-like
[  47] CCA9EFACEDDDDDJCE9AECCC9E88CFCQA557887887787768645CE89HGILIIGA56G257 HT*8OGDEEEEB89HLJHH-NJAAMUIIIIIGKMMNIQTWCNHLFFEEBB96FEEHCH44LKJ9TJVQUQD6666877HBBEH76A65GGHK7KCC722AMEPbVFPMO555555567777777975987588B9LLLMK667MLHGJGFFH88BC888767BC8HJJKH666667766667UINGGCCBKJUWYZXaZbZVabbZcZkXXXPWZbfSPTVgKKJIIIJHqSLJJKIKJJKKKKJLJQJKMMJBE9FHBB9B9AC99GF897ACAAACCDCB899GBCEFDEFDDEEEEBBBBBBBBBCCABGHGFEBFGGEFfQSaWXUWcUVRVSLpPOPUVWTaKEFSIEFCROFHIDDZEGKMNEDICn9KORRN55555EEbcgGBDOKINGABCDBBBCCBP-IIRHGQFRJTE3cPPPLLKMNPPLMGKHJDQPKHKIIORCCCCCCCCNIICBGHG332333332243333333333333333235HNUJAMYVKOYYYWYXLNPPLTTTXQRQRCOcUYUYYZ57OPJGFRGJYKULYNADC9878JC6679787ACBBJJLGMADAFFBDKDDE4IAHEDFDHBIJLHTV9PEFDA9CCDCDB999999999BBBEDAARMCPDDQLUUKUWTVUNSYSSSPYUWWPaY41AEGBD762777RMZQOOMWVVRWSSSTV-UTWWXTTVUVVTVUVVVVTaccSQILLQPQPPPQPPQPRQRPQYQNOOOPTE5MLKLLLKHKLLL555J9A9BBGGGGBAOLUDDCFDF9BBBBBBBFBBBBB8B8A7IBPPPPHRNPGKOKNENLPDBC8ADBBBAKNMVIIIIIRPLLMKLMLLLMGHG999933CKCCDDEEBA988888K5832527-8565853666565367565CIGEEBLBCBEJBK 4634MOT-tQJFPSSVXtivhub***yXXSTQRTVSQRPRRSROMMPOs*y***yxxnRPMRONOHLKDKGHNGKHGCIHJKKKNMCBDRpLXZZRHHIFHJMVRW1Vra*******vporprt****r***4*y*kxyr*tw*lfvwlqwno**tsm*knyb*k***rs*dx*bEVSJ*CCBKOif**kidJIsbslU --------------------------------------------------------------------------1--1--------------------1------11--1--1---------1------------------------------1----------------1---- * c.56 Phosphorylase/hydrolase-like
[  48] 557694BEOLLRCLLDEJEC9C9BJBBGDK97DNJEADCC88C9K3XMIFTaX5CLAADHEBBA8287 KZ*IhE9DBBI997OQQGG-GRBBKOFGGGFFTPQPOKSSLqdrfKWMDQTFSKMPME44fWJEfMeSVYL766675545BAOIIAGGmfkm7nGG3--KYOTKndfJX55555555555555CNJQQUHOSWdL*****455*M*pj*oplKOSSVWLLSRUjQpx**kCKEGFECQHKCFFIECFJMGEAILJMJNHJLGHJMJMICGNNIOGHSBEG9AMI777778JcEFFHGHIHHHHGFHGMHEGC5A989B7687BLP99HH7HE987FA8AAA8888999D8AB9ACA7885555555555555FDCA8BCCBCHC3ZQKJKGJJFFIIGCIHIQFFH9P9CMDFKKHGMGWCOAEJ85CK9CFNPeRMOa34444PVacWLFIIRJNU99DD8CC9BAJ-gZ*peyksOWG3eQQXVXXRcPbcXRIFFEKIMINPFHDPPPPPPPPkcaaViak11--------2276779868798892131DDKVA8HSSLapghgoqgZaaaaZ**mmmkVium*aPOK9GJMGSKOHCAHLKJ7ADSRMCNKFBA8A9A9RMWgZZEeZRISolOrfdbeOifledYrOafdhgkoafILGMBB989CA9C7686677KMIGGWSLKCRTHH7PAJDDECF9DDCCBAFDDF9D91-5aSIM11-111GKLMHKKIKMMIKLIJH-KKIILKIMJKKIKGGIGGJHNMHFROGKKIKJLJLKJMLKLMMRHHFGEFGJ3FDDBEFFDDEED5587BBBBBBDBAWFbNKIJGGDF9998BE87FC99DABD898PRUSRRNTSJMNNHOJMRQFACBBDABAENLLIGGFGGLHFLNEHPPPPPLKLFFFF44mEJJHHII22222222918--11-----11-----2--------JHKHIIGHGFTxOU 1377KIM-I753DJLIJJHMSTOWXVREEDEEDFFFHIGGFGGFEERMJKQQWeNONMILLMCBBBAB6CDABABEE7CEBBBBABGFFINEJFKHFFGPCHDXLc3L*L*po*fpVSJFXQRQxpItN**n-pa*JTLOnJKgPDKMJNWIDaPNIMSBGRSuIeqsZi***WdJecX*SSSbe****H**IHlmgsd -------------------1---2-----1--------11----------------------------------------------------------------------------------------------------------------------------------11--- * c.87 UDP-Glycosyltransferase/glycogen phosphorylase
[  49] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1223--Y-1--------------------------------------------------------------------------------------------------*--**********************o*********************************b*v**Uy*8---1A-----1---------11-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.18 Complement control module/SCR domain
[  50] AAA889PNRPPRQQTJAHIKKEEIH99C8CDEEGICAGKKKKKIKEIICKNPKCGICEGGJCKGA-66 PPiGkIEGHHGGIEUZgTT-TQIIhuTQTUUWWXYXYY**MURhKOQGIMIEmaiOMRCCcWeKbY*jmYK8ABA88ACIIEYAEACAQOPMCIEC688EIGKGUIKGIAAAAAAAAAAAAAACHIAKGGCKIKIQSSOOAACAWKQQMMMOGGEEAAECEAEIGMOQYGECCACCAGAAAAEGCGGEE8GHMTTTTSOSWGSUSSPUMNOOMMSSQKRWIKKCOQQQOMIOIKKKKKKKKKKKKKKIMMMKCAA4EI4B82AOQAAGEAGAAGGMGGACA74668AACAAAAACACAC4444444454444A76888888AMSMObBCBBCCCNCMKKIIA886EEK66NCEKDMKGFKGIMIOLGLKKECEIEQIIU8AA8ASO*quMHOiYegeMNMMKKMIKIY-UUfQSqQegcG6YKKIOSkaUOfeQYGMIUacQKQYUScSSSSSSSSSSPCEUOQ66666666662244444444444446666GIOuIEUkaVYmimikkgWWWYggs*ggggOgea*YkmaCIOMPOMGMKUOWaxcEGSKC88JEAAAAAAACCGUQSAeWKSIMKGMMMMOAUUUUQSWWVTTWTIQOcCAACAAAACBA8A8888888CCECEIGMIUGKAMEGEIMOKIMMKOIIIIOKIKISQ846OIGCA88AAAUQSOQUOOQQUOWUWQQ-QQMQSUUQOQQUQQQOQQQcgeYSKLMWQQSQQSSSUSSUSSOYONOQQQOA8SOMOOOOKOOOOAAAEBDBAAIGIIKCTMGEEEGGEAEEECGEEGKKKKKCGCEIVCaYYYMXKVMMSWOIMIKGAAA8CA8ACEIGQKKKKKIIIIIMMGGGGGHHHAAAA88GADEAAEE--------A6422224-644667466644A444222EGEECEIDGEIOGC CC24IGC-eEC6ACJYQTMUVZTneloMMLMMMLMMMOOONNOMOOPLQaUelyQTLLMOMLIELJFLFFJOHLHNNBINHGGGGGJHLLWIQNPOPMPMJ9FULT4IhCWVXNONRILHGHLJWYKcM**N4WQgKNLLQKJXCCJLIJOFHXGDGINKdqDSNFLrMI*FIVEKNNI*HKIRRta**MfjSPXKIHD ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.36 Thiamin diphosphate-binding fold (THDP-binding)
[  51] -------------------------------------------------------------------- -------------------------------------------1-----21-------------------------------------------------------------------------------------1111---2------------------------------------------------------------------11-1-----------------------------------------1--1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2111371111421111221-3333221121215--2211-1--2------------1------------------------------------------13-----------------------------11-------------1----112----2---------------H8-124EBEEBBBB9CA-D9AH948DBDE8C99B997EA9237FGE5CDDDEFEFDDEDDC84335687--9BBBAB99BAAA--------------11--------1---1----22212-3--1--6756-314-1231-333-------------------1----21-1-111112222------------------------------------------------------------ IFFH**r-*TU2SNeJMONKLLKKKJKJIJLEIIIJHLIJGJKHIIKIOOUTSXEMQLJLKMDJIJIJ3GGLIIJMNBKMIEJJIIMNNMXPMQPMLJLLDGInmq2********************************************************************4bWN*NNKRQ****O**SG***** ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.7 C2 domain-like
[  52] 77AA77CCCCCCCCCC9AABBBBDGCDDBDCDCCCFEFFFFFFDECFECCFEEFEEEFECF8A9F599 GOYCMCBBCDEA9ACDDDD-DC99FNDDDDDDHFFFHIRLBLGIMGDDDCBDICCBAC77FHIBMGJINJF9999B98AAEBFFBECBPPVH8MGG5-1JWMHMVaUER333333333333335DCFEGDCEGFECDDBBAAADHNDDCCDCDDDDCBDBBBFDAEGEDIBCBBAABCBBBBD9AAABACFCEEEFEFEEDCGDFDDDGEHHHFEHECCFECB9DBBBBAIFAAAA9A999ABBAD8A9AA9F7488987674798888879797AA9877A78888888888989888AAAA9AAA9A9AA888888888BEHHFHIKIHJIJFGFFJFFCDEDFDGA9DCEGHNJDKDADDHJCDHDCGKLFBNKKNCBAABEKeTVHGGNMMLNHHIIGIIHIIS-PKOKLRLSMXI8WMMQRUTaWXQUQMIPJNTPPNQQJRPLLLLLLLLKLLJHPMN88A888888833333333333333377779JKYJFNYVKSdXXZXcUOQQPVVgdUUUTKRjScScbSBEMLPPOMHIPJWLeNIMTKIEILLDGABBBBEFGJOYHINFLFKIDKOLKIDPLSMLKLGMJJLJUjHEHEGEDFGFFFF7D7777777GFECIDDRQAILNOEJLLMNKMKLMaPNOMKMTNLMQ9-DFKDI532555KOHEHNHLTTOLQMQQL1UMLNOPPMLQVSPJMLLLNPRQFEKIJHJGJIKHIIHIIIIJJNHKJOOPOH9LPNOOPONOPON45AFAAAAAFEEEEEUJNHGIGHFCCDCCEEDEIILLJILGOKLNVUVUSXXYTWUWTSQRRCBBBBBBBBJNQTWIIIIIZVWOOLKNMNMLKLLEEFF88FENNJJII43434333G6421214-225232133326223311186AA998999AIDF IGABOMJ8*jNHNNMIOMNVOONUTSPJJIJIJLLLLLJLKLLKKKKLMSRYpXLPMJKJJIJIKHJK9IIJHJILLCJKJIHIIHHKLKZKOPGRNPPJFLHSRdAK*h*mxpoqYTUefado**V*a**w3*q*TabOuYYpcLZXdVkVRyXpTepXa*Sz*SVoUh*UYsUORRR*QPQLL*e**Ls*OThUWUf ----------111-1--------1---------------------------111------------------------1---1-1---1---1----1---------1--------1---1-1----11----1111------11--------1--------------------- * d.79 Bacillus chorismate mutase-like
[  53] --------21--11---------8fBBJ5SOP--12-133335AN-EH8PG5B-1-1111-------A Os*7U466778645ACCAA-AG44BDA88998IFGGBEHEALJNGA7679A7ACE45711IHc4d6IUSUB444475558OAA458AAmm*f-n543--8kAOH*n*ft111111111111112A83CB69JJX7ssolkMAE*4*j**ihIJMGH655CC9ViIe***W554554574534XNF99354KGOcdgcighhRjfknlcMRLKLJihsELLWBQLBAABAB*q79989888889998878886A676BB645466655BB655665575BCB75677776666667666665555666676557445524347AgOT*ZYXcdacaZWIhjcIJLITNQ79FJNO8lkaNHF69E6A8C9537pOfymmk89999US***VNQnsjnrHHHHGHGFHGN-*y*t****Nhb5feeiihanvmcYfiUMYQHUXTWXKbMGGFGGFFGHIHCF*gg33333333335A335534433444422224CQaFAKMJGPqhkmsmjSTUPji**ZZZbIaop*lmpv28cgZ*fmPQ*pgmlFVZmNMLLiM4444444DDMUs*h**eSS*kF**wt*4*******U*******OzW9CC8666657565555555WYCESDDcQDhamgHmXLeRXYWOZUcYXUbbVcWji--5HMLN------OLMMLLGMMMPMONQLM-MOLNNNNLLMMOMLMMMMLROQILHGFNLMMMNNMNMNMNNMOSJJFKJKNB-NKLMNPOHKNNM--4E77777BCBBDT*Jk444433132233237FGEFH8GBFBYXww*wu***jy**xx***322213312HQTSdYZYZZbgggjrqnjojkbdeCCAC11*7ttMQYX44334333412-------------------------8D777776668*4D --1-FE1------1RGIKGFDEEG9EB5544343445555555555HHABFGBKADA88ABB432111141132211-11133343333683I4B28798A5598C-C1S------11--1-1121-1-131---1----1-1-1-----1--1----8----4-1----2--6-1775U12224s8EfMEL71Q3434 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------4- * a.30 ROP-like
[  54] 776268754455544A38DBA9AEF678A5H72-211175775239371BFBI1DEDCDED8966--6 FEHEZ676667756G6633-3F117U333336FGGGGTSQ9941HC9F2GH7OLHA38--ACR6MHcedXD743377776LNJ33---EFHC-F22A--4MAC8MFI4E433333333322224222223112B3DIIBA556GHQDGAAA666667777DB794BGDLG585555585555MJBCCB99KEMkkmkmortYnlnuqrFNVVHbrkqJCGg9HDBCCCCCmYACCAAACDCCCCCCCE99CE69C5885C666MMAA8B7AB7646665553333233666666666661111111111111-2277722263IHGMCCCCACCF8DABOOCACDCI356838B6UTBL-5AECC45656M8F-DPMMK242267CjTZ84JTSUTLQQQPOOQKQMj-KLYJKXISM*D3*ssdqyo***uqYPHG9dxhdYfeps*EEEEEEEEE8AB3KPh--------224422332222322224-61WBEKBBWlfPqivvwtmVZddZnnmuigijSe*fhsqsn4CkkkSWjVYrXieqSJTY8FDJgW8BCCAB997BFMNCGa1WIMONMSRRS4O7O88J889PNLPPJ5AFDHBA9989872822222224E42255qdNLPGZIMRbPTUURDLMSPPHMLMOHML--338552--111RKSQJVSQOPQQSSQQP-OOORRPOORQQQPOQQOOPdkoSTRMOTRPQOUVSTRTRURQakLKLNMOHB1YQOQTQQLQTTT326G47266CGGG6BnUsDDGBHI4DDD9C67FmhihqTRBLLJCsrvqf*hrjgogeXPVTDCB8AFB9CAXVVaORRQRnbhgeYYQMKKLDED4444--6HDD6877--------B2-----------1-----1--------A82BAA9AA81M99 E5ACQKP-aD97IONFMLGDHHGFIGGHFEHHHHFEFIDGFFGFHHDKILLPONDIMKLOOOHBC88B7C9BEDCDE7CD6DDDCCBBAPULMPPRJFIJKIIgdX4E*W*klaZiQIFKJMbMrhFfH**o1kVpAIKIeMOXQGQKFEXFBdCXOYUcaTGIHJ1QCESKUSTQgfV*ZZY*b****M**nf*vvyl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.39 Multidrug resistance efflux transporter EmrE
[  55] --11111-111121215-111--52--221--346-1-212211622613B873434-4221--3--- 2544O644445464E89BB-BT77CACCCCCAJGKLBDFH7BAO88A467739BC41A22C963B87JHF78666BA9429D323322HIF8-9886--4B455I6G1A3333333333222224334542352445567--1B2647955A4444322213464578442212222212128471132-83A9ABBDBCC8BDCBCC65AA9BCA9645E676866769AF6HEFGFFEHHJJHKG9CCD8F9897784577778866733555989B6BA8DA55422344434324ACGGEDBEECBBB79A554A793353BF6769CDA9C5FL668533G867716F21A632152232444311434FC5541221278HCB3579AABB22222222223-78687I9D4A4-5669AA8A86548A64486577774533333333326637847----------131-3411221-11-211214796126343A788897999999E99B993B99D586617447797438DA6A634C142855332232333268977852-724A335439C8E87B4A8978AD697231122221-121111111211-68843335B3-33454334233444416333641-3-2-4------78664748HGA8A8B77-H88C8AC9CBHBC9998998AA55674767787787868A778778677894-688769788566--4325334655624D26334554333324-1411321-431158BBCB5D9AA56563AAA213244141-1114222224214478788878884555--21772222--------61-------336-33-----32--1---35223131114654 aTJL**w-***gccbkfmbbbdaegegccaZabcZbacYZbXYaabceYadhmwbbcababbTQRQPQCRTRUOSTTIUWQRSSRTTTTUqTfobsSTVyUqOlkg6w************************O*****************************************zO**h*bedvk****g**kq***** -------3------1------------------------------1------------1-----------1----1-1----111---1----1------------2111121111------12-1--21222----------1111---1-1-----1-----------6121- * d.3 Cysteine proteinases
[  56] 76BF79HEGGGGGGHI7FFGFEEJGAAFDBHGDCDFFJHHHHHDECEEFGOIJEAEAAC5BA9892DF FKREdDAECCCCA9KNLJJ-JOBBNQJJJJJIQPRRMNddDWLNJKGHDGF9LPNCDF88TNRBYMbUZRJCAAAEAA79ECHEDEDCHGGF6L775338EFIGMCKDD444444444444449CADCDDABAHEIIIMM877RHNHNMHHICECCCBBBECIFDFRNPKC99CDDDACC9DJAGBB79AHGLFEGEGGHGEGHJEGHGMLLHKHGGIIGPNFGBBBBBAbXDBBBBBBBBBBBBBBDCDDDC97ACCDD7B7GGAACCBAB996999AAA8677EAA899898988898877787897778C99888A999ASBFJ999BBCAEAEGDHG8AA9DAC76C79GCNNGEIE9MBBBB9A468FDJPIIPAAAACJNhVXJHHONQNQEEEEEEEEEEK-MMQLOSMLLfKBOPRNORSSSRPSLQHILIGMIIJIKIKDCDDDDDDHGHBIKLLAA99999999445555555555555AAAAAKKOF8FTLKQJJKLJKKHIIHIHJZLMLNEHLLTPcYT9GJKEOSMNMSMOOXREFLJGGLHGBCBBCCBKKIRMLBQfNEHUGCKRLJM8HGFEKBJJGTTTTVfMRE99CACBCCDB8D8888888CECEDGFIGFJNIHFJGJKLIIJJKIJIIIJJIKJII938GPPL453444KJMJGHFIJKJIKJLII-JIIIILIIIIJKIGIIIIJILJJJISHIIIIJJJIIJJJJIIIKHGIIIHIEAGGHHGGHGHGGG66AFBABBBJLJJKKXLLBCBFCF89999ABBBHHHHHEHDDFMHSSTSNVSUQRMQNKWXUFFGDFHGDFHFGFJHHHHHHJIKJJILMJMMJJIABBB9BK7JJFFGG2222222284311111-1111113111111311111656567A798EIAG CE45NMZ1*TSFPPYQMONRSVReTbVKKLLLKRROONLNMNOMLLMLLQTUYfNQQNNNMOJGGGGGAGHFIGFII5JIGFFGGGFHHMTJMNKOJKKJKLJTTR2R*j*fjgqjladbYcig**V*X**y6*j*UedYpYfnYRcYUVrbYzbjae*au*hthaR*PT*iZsWLciW*PNOYRsSotNdZUWnkecq ---2--11-----------2---------------331-2---------------------111111-1-------------------------1-------1-----------------------1---------------------------------1---2---1-222-- * d.142 ATP-grasp
[  57] 44235544333333576355655777785965856765A899AAC9A86BABA376666784444112 IUO7*D9QLLM635NHCCC-CS--GeCCCCC9OIHNzeepCik*vwc3QXVDlni66K--*wNF*Y****VPFGFccTE5nSE22111RLNG1D751--1q8I7VJm6M--------------553HEDFAOc43CIJA96AAe3kA8TADR34893332337517KPS3321222222232CC833DD3fJMnoplnkhrWguodljaUXaSVbfoCMMQNIIaTRXYPWoIMGGGEFHGHKLLEGA87NKqMQ7TaBKNHRchQMceLMIWZEZVcVNPSTRPRNLPPOSQSPUQQSQQWXQNWYTNOONQMPIFISKPMLiHdpgYZfiYabaQSt*qIFKGeDII75fvA7bfjZH7PFAPGONJ278749*WZV4YP4pPHiQbOFFIMCEKFEDEDEGEDFe-ZSZMVoWUNsN4*eejws*****tSWOISMOcHKGFSSSEEEEEEEEPQNBARUZ333333333344659A358663663E2EE2ANOM2HOGCUajntpeYHGFDYZgoXOOQFWlorLPWU-3PKOHCKK9iPjFtf8BE568BDDBA8A947GCAN68CUNC4CC7ELF9EB7HUNVEBWBKBEBFORA951222-2--3--3-------42128B8PQWLGKKBNAHCMefSHGBI9GDCGEIDAK--7H56F------YmfrEaPWnmYWgZhiW3kVVbXgdaVkrdgWbWZbVltknex*qXVQQSRURXSTTZRPXvNLWQPPnK1eUSWWUUQTYVZ--FA8B978CECD12YKXCBCIBCDEAAASFI8C7BDDFA638UQQRYYUZPfFXaTQ9bTL4333343335NOOVQaPTaWRITRPELIIILFHHODCF1-I7CCCDB911111111D2I----3-11--3-----11--1----6I9767G9883V18 1111211-421112122222222222222222222222322222222211222512122222111111121-11111-1111111111122324332121121223114-VbrokkaOLLHRWNxtDgN**Y5nR*FPLIVMQcWERQKJMFIqSTPNe7B8OH898M79cCHA5111-F11123835D2422251224 -21------3-1-113-----1---2111--11-1-----222223------23---1-22----------------13---1232312--111-2-32223-21231312321133--23-1--25122223-1211-1232123322-1-312223----2-1-3---1---- * a.35 lambda repressor-like DNA-binding domains
[  58] CC3643IOQQSQQQMI46GACA6XI88984AK44444444444444444444444444444ACC6-66 9FQB*C4F779787***tt-t*LL**spsstv****y***9*i*B9DD9A87PQOBCO33**e3*Y****O2222222-333N33533644B373352-ESJKEsOODH33333333333333354338333433GGGNO222i9C8BF9AG3333775554675NIGp8353333353333KEHDB333HD*HHHHHEEIFHEKEEFEOAAGWFHFEIEIL95777777jE3CCCBBCBBCBBCBBBAAAB94777777474667777777867997AA7B99956B55555555555BBBBBBBBBBBBB677555777948BHCBBBBCBB8C8hBHHC66638921J76A6KIBF6G4AJ644A4666I3KnXXV79999OGgZfGHKcdfZVGIIHIIIIIGK-GGUGJaENMUg9OOOOONQQPSOOMcJMGJMRJHJIHOT33333333F8858EDJ333333333322555536534533533334NO*V3EseRiXTTkeradeidPPgWtptuPuve*Uwxl79VXVOKSXVZQSkrkBBN6658KB5555553888cSQE*OYE36763A5553OOMHSDcBIIJDJ**FE365335553575355555553333377HH7DJKREGRJMLMMMMPXMLKNOMTMNOS3-7BD75222222OCfF7FFFLLOFJJFFF-LFFDDEEFEELEIDDFDDNLNMMDPUHBBBBBBBBBBBBBBBBQBBBBBBD72IEKFIKJFJHIH335FCHCCAMMNN9LYHT5553A5355355793LKRRLFRIICTKbbYeV*VaTaKZOJSVWA555555557BDDRACCCCHKLLIGGJIJIIORS6777557CBBACDD444444444-9-------------------------55644282225M5C 547A**G-SC86JMJSaxa*cim***xJKNQOOepfVbacUcZONMmlZkflglTbusXURSEAEAAC2EA8CAEA95B9AEEEEE888OUIaGILCECAGEMUIO4K*HzSWJGMNIIGIKJLdcEkIt*N-XJYJJMIIHLOGKKCNFMHHSLQSJYGKQFWVHXSHOfOQcLDZgf*b9Zn*****p*uJLSPQF* ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.95 Thiolase-like
[  59] 95-1--ADDDGDDECB-253643HC666217C211-1------12-12--1-1-----1-16771-11 6899n6-6222B48r**ee-e*55**eeeeex********6*J*58674794BADA9B11WWo2RQidViO111111115A8D1111233621344---2B76897797--------------211111211-119A9DD555EA5325334--11------21-1336--1-----1----BCC9B445G756666648677667666666666768FDBC22111111642222222122222223111224224421223881133332221---333344411133333333333333333333333313311133343672A6666677677455523223726391153FC49EG34B33335242D2-XNNf33333C7oXjA9BZMaZTCCBCBCC9B9C-FFJFGPFOIFg2SHHMFECHFHEFJUCYFCFHCABBFBM64666666F3313ED7111111111111111111111111111113SZrV2CbOHaNQTbgPLLSSMKKYLVVVVHTnOuo**y58PQHJDOOMaPSSek8BD2546992222222536MEC6uMQ2-2117-11--CDA5I5AA5BBDBJKED22112-------1-------1111211763AH8C9HE2777777BJ7787C8JA7AC1-2562211111153952325667577656-6656656745667665667576239957764677665757557445553451-355565545565111844544AAAA5OG761112121-------2STTRTJSAECO3ccbeKaMVQPQOMJGFG33333333331114222224725699A889H78811112235EEBAEE--------214------111111-1111-1-1111154255454442616 77CEhhj-cGGAVVpbZdaZUVXcUUheeSYSWVTTZaXYWYZZabURRTUVbkPVQTRSSSZOPJJHBLJINLNJLILLINNNQQIIIXsfZaaYVTTSaZi*s*5prZ**********************B************u******n******z****w*t*m****y*GUTJ*LKJUXv***Z*YYS*w*ud ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.29 Bromodomain-like
[  60] 76-4--CKPLNOQLMF2195753RH778429D54A1--66664BB9DC88978----1-11777---3 6AC9*CA977AJBG***kk-j*GG**kjjkjm********5yc*855B6I94HEREEP11pdQ8*e*pk*J4344444-6EDN32432CB9A-A431--6K554o566611111111111111256568536785IHHHI555*9ILK7LMR2233333533633AVItA333333353333A77CD1-3FAjGGIGJOENHHLJNSF89KKOWGHUCLFJE87444444z63888888888888886665631212212121172222121333444223324218612221111111222222222322212212222225---B3333C33142Y3AA1-1-3-921C42C3HE94B5-1F71125-22D5ARFFQ11111BAud*978kejcY46674465657-IHRJIWFHENQ-FEEJABCC9FRBJYAJ8GIQAEEEFHP44444444D9336KEH----------111111111111111----4GLiH1BTRGQRXZYZfsRYYMNLTb***yRnjQpku*g56MMWGKLLHkIRWie54K4144L8222222286FTIK7xYQFDHFCHEBBC2DED7F99BCDFFD*fDG33321333332141-11-111442732EG38EAD8B8AAAAAAOEDAAABF9DDBFG--16DB4------L7WF987AAAMAKKDBA-8BBBAACACD9CEA99AAA98DRDx*797889A999A889889D67788871-8BBCCC9888C9---646665BAAA7Eg6O333263133323334EEFKE6G9BAVFcgYdzmknKWRXUCgV*7444454542677JCDDDDBD8BC88967666665444--53AA44662222222241---------------------------11-------2H25 F767cfF-fIA8LKk***s********ljloon***vmrnpqojjg*o******zi**iWVVJ8C9886CA8A8CCB8CA9BBBICDDDo*Y*YbZA8A8ECcdde3O*W*o*i*fsceaadYe*sW*i**m9wd*XcgcfeYgTRTbZWpdYjcYYTpWh*P*dprkPi*XduO9GGI*EDFLHbkk**nxFHkZYVo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.23 Acetyl-CoA synthetase-like
[  61] 335144789999999722333224A6665478333333433343344333344145556384441-44 BHPEYJFIHHJIMFNLKKL-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-IJIIHJJIHJIKIIIIIIKMPKNNKJIJHJIJIJJJJJIIIIILGHHIIIIF9IIIIGIIGIJGG77CLEEEEEKMLMANUIKFEEGFFBCCBBDEFFPPOQPIHGDHMMZbYZLWQTVMOMKMQONDDCCCDDCDEFIJMKKKLKMOLLLONQOPNOMNOHHGHBBEEWWQQSR77777786C8622229-425453344455734311176776878888DAG AA22LMJ-YDA1EGHEGIFJJHFJHLIGGFFDFCDDHHFGGGGHHHFGELKNNLFFGFDEDDIDDDEDBDFDEDDHHAGHDBCDDDBBBHOEGHGFEFGCGDIOMO-IjOXLQNWORFFLJILIUUHlC**b-jQqHEEHMFMZNEJJGFSGHSHcKGSOf*HVIIDdILaYMRJJQPK*JJIONePbmIcRQQUNLMP -1---1-----------------------------------------------------------------1--1-11----1-----------------1---11--11--11--------1---1-------111-------------------------------------- * b.84 Barrel-sandwich hybrid
[  62] 5532448CCBDCCEBA4487743FH99C739H--13323333312-1-22333-55555556883153 ENZJrFFLDDHFECk*ydd-dwJJz*fdfffq****m***AyR*AAAH6777FGHEDI55PSj9UVheVZN444444416A7R86777MMIJ6JBB81-CLIHJWIKJI77777777777777BDDDFFDAEEFCNQQWW445FIIDFHDDDCCBBAAAAAADDBFGGHDAAAAAAAAAAAAIIJGG666HEKHHHHHEGHEIIIFGEHMMMIJGHGGQLOH97777797QA8777877678887787556751434634332875545365554545565645444444445444444466664455455466444444456CA9B866897798A99CC78889CC88F97D9EFAEDF9GE676J56C8V7BYTTk58758GH*koJGJohohbGIHKHGGEGIL1HGTGIfHQSZm4SIIHPKQSQWUQMQNYPKPSMNPPJQc77777777LAA98VXN444444554434667668765766743797VatT6F*nVmRWYYiTNMNNMSSaeUUUTIWdV*o**uABZXOTSPORlWggo*CFP8656LH6676666798cTRHyRT968757A6965MKLBSCH8BQPPOZdEA566555555555555555556556777IH8LODRGPMGMLMLMLNRKLKLRLRNKQP517CDA9223222DCIE9ECEIIGEGDIGG-JGFJDEGGGIIIGEEFDEIFEEAADCCBECBCDBDCBCCEBBCHBFBDDDE75CCCCCCCCCCCC558KDDCDCGIII7KUCDA9A87988864A888STRRSGNKJINAaaZcLXQTRPPPPMJIL6666666667ABANBBBBBJOEIIOQLNLPOKKLAAAA55F8LLGGII33333333C53------523--------4-------6A557555556G7E 7722MJH2jJD4rkRPSPGOJMJVGURLLLMKLIGFKNJKMKKLMMMLJPNMYSNKGDDFFFE56444144556577367566676333FRDSHGDBBB9DEMTOR-P*QyaZTbWWSVOQQSRoeTrS**k-*avMTSSUQQXVNSQRMWNPeTZVRiTkqIkPMGTGIcWUaVRSSK*MNPXYuep*NeeYbeHILp -------------------1-----1---------------------------------------------------1-----1----1-----1---1---11-----11-1--1---1--------11--1--------1---21---1---------1--12---1---1-- * c.14 ClpP/crotonase
[  63] 224233333333333336555449C5699957**E485B9EA77j68HTG**u313261334339133 AEU3g22476733254455-56444755555489994BC99G5OAI547A84CJ843422lg96O5DNPH655553433253C4362388UV3B332223V39AXMX5c334444333355677A8K*oHLIH59OOPUN222UA***ozz*OPLLTJAGRVThef****8I9E8E9d8F98A673468156D88A89A77487BB98D9HHBG979846C898755785Bc344444444444444754655454552313565445744333254422232223553333333333333333333333337332223333853LF4445565957B9542443O39224H4357784443634445718473hlOO*7NJ9NKImUIM69HBKaRJM5IE5KEI5j1keh**v*MjLG3FLKjXksfVevtyBC6QcTkWELSzZy66666666HBA7fbfA333444344477663366666366433346CEI84ImYWJgNTXWMJGKKKOO9EOPPN8KJLBAEDB1377iL78A5BBKLT8GX*6FHhNA69JADBJ53C5795RDjA4*96BV457-4b63JBa7QCHACK*CA685GM346511121111111F42G722D9A67i84A8H85665B9E878697BQ7CJ317B6881111119BFUBDAGZZOMGJGKK-TGKKPDFJLMUFWEGGJGF8A6OWUVOEC9AAAF9ALE9F9ACPEBDLHDB73ORURUTTHPWTR33f4555558G8985*8IC5B3235624-3-58668R66953G*MGGIGcOsMRNKGB4Oxl3333333336565C89997ICABBPRdVSVSKKLURMZ11g-9987DC1111----B35------1-2--2-----12-2----37556837567pDD HA21pjn1bEO1359XGRihkxMrgpV889ADF45476666559BAiaJWgs*t**IbNKHK222324-32122264244222223222DaJGCMJ76655I76IT-o***PKTMNNGBEFJIFYMDXG**c5UPgEIEGSDHOFFJHDCTFCOJJDEnJNWS**GCG9DCDE*88s*d*GMHmP****Q**MM***** -----1----1-1----------4-----------------1-----------2--12-11----------1----1-1---------------1--1----------------------------3--------------1------1----2--------1--------1-2- * b.80 Single-stranded right-handed beta-helix
[  64] CCDADBEGHIIHHHFEDCDDDCCBCDECA9CCAABBBBBBBBBCCCCCBCDEDAEFDFFEEDCCC9BB EEFGGDDDDDDDECDDDDD-DDDDDDDDDDDDDDDDEGGGCCDFDFDCDDDCFEFGEHBBFEEDECGEEECCBCCCCCCBDFGGGEEEFFFECFDED69EDDDDDDDEDDDDDDDDDDDDDDDGCCCCCCCCCFCHHHFGDDDGFHHFGFFGEEFFEEEEEEFFFEGGFFEEEEEEEEEEEEFFEFFDDDFFGLLLKLKKLJLMLLLMJGHHIHLLMGFFHGHHGGGGGGIJFHHHHHHHHHHHHHFHGGHGGCHEFFEHCDCKKGGFFFEEDFEFEFGGGGEEEFFFEFFEEDEEEEEHIGGGIHHIHHGIFGFEEFFFFEDJEHHKKKKKJKFKGFJGGEDEDMEECEGDFDBFFEECEEDDEEEEDGDFEDFDDDDBBBBBDDGFDEDDEEEFDCCCCCCCCCCE5FFEFFEEFDDCDIFFFGFEGHHFEEDDDBDCDDDCDDDDDDDDDDDDDDDEDCDFCBCBBBBBBBAABBABBBBBBBBBBCBCBCCCCCBEEEEEEEEEGFDEEFFDEGDFFFFEEFFEFFFFDDDDDDEDEEDDDEDDDDEDDDDDDDDDDDDDDDDDEDHDFDHDDEEDDEEECGGGFGGGFGHHFHFHEGDCACCBBBBBBBCBBBBBBBCCDDDGGGGDEEFGGEFFDEEEEDDDDDDDDDDDDDEE7DDEEGCDCDDDHGFEGGEHHHFHHIHHH-HHHHHHHHHHHHHHHHHHHIIJFGFFGGGFGGGGGGGGGGGGGGGHGFFFHEDGGGGGGGGGGGGDDEFDDDDDEEEEEEHEHFFFGFGFFFFEFGFFEEEEEEEEFFEDEEEEEGEEDEEEEDFEFFEFEFFFFEEEEEIFFFFFGFFGFEEEEEEEEEFEEEEEEEDGGGGGGAAAAAAAAEDFCCCCC-GBEDDECEEECGDCEECCCDEFDDDDDDDCFEE OPDDUSI1wIHCJJLLMPOMONNOPONONMNLMNOMOOLMMMNMNMONOOOPOPPOOQNNNNMMMMMMFMMLMMMRNERQMLMMQNMLMKaJMLKJLKKJILMRRTBPjUmScQYXcUSSNTQRjgQaU**S3Za*OTQUcRPXNMQORQPQNaVRQPSPZtMRPNQUNNqOVQOPOOP*QPPOPYUtvOkWSSfbPQP -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.104 Class II aaRS and biotin synthetases
[  65] aZ9QJajOWVTVTVUfBEbTeYXQcPPSKUZUOOhWWWYZZZaciQhYXheigRIIHKKKKKGGI3AS 7FD3H87GEEE7BAAEEII-IM44KEIHIIIAOPPPKFJHAJGMCEC7IAB8KGG49A22OMH7GLSNdTI644466644A5IA9JFHCCBD4G682--ANCFLH7FME65555556657777ADDCBADDDBFBSSSVW667EHfNVPJKJFAIIA88886MDDGccWG574545675476D98LJ883BMSOOOOOOMPOOPOQPPLKTSMUOOQILLKPNIJIIIIJQIHCCCAACCCCCCCCACDCDEE888FF85868A888FFG98664977DDDB777ABB888888888887777777777777C66886666A4OHKOIIIMKMLEID6GRRIFFFCC895G66MLPSUWCIHOGE8654289DGFHCCE66666BGVLOSFDKLHHFBB9BBBBA9BG-EHQAAVCGMPE5PKKERLVRKISUFF9C8E8OFEFFBCF88888888FHH88TII55655555666666466665656655555299E97EBB9DSLNLNNKIGGGRRMZLLLL9LMTNGVIP6AKKHJAIGJHIIPN89DTKGCDPL6666666DEDPKRFadXMWfQFmVVRQ8FFDFFGBLAYYlaScCb743334332462622222227A34788MJ9KOFMEIMIMNOONDVSMKLPQOPKPQV1-7JdJJ442333KE989IEDDCDDDCDDB-BDCDDDDDDDBDFDDDDDFHHHAACCCFFFFDDFDDDFEEEFFHDCCCCDD72FBBBBBBA9BBB556977767AA89CFNKL777666766645886AAAAA9EDBBICNLPNHGJIMJIIICFGF965646646JLROOMLMMLLWRSTGGDEEEEABA7666AAQC9977BB5665555599622222-4213422333-2-243444CB9AAGEGGG5E96 13--rtX-LA75KLbFFHEGGGGJGDGFFEFFFDFBEFFGACEFDFCFFFFFFJDDEDEFGFBCBAD62B83CBB552666BBBBB7B9GIBFC9CB8ABCD9Zae-QcWYstdukeOJNNMfM*uJhQ**o2hg*JOPFlJTZPBTPGCmIFlQmMVXJNMXPJNA*FLOZhJHEGIV*NMKLN*p**GupORYnjhM ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.37 CBS-domain pair
[  66] -------------------------------------------------------------------- zu*-------------------------------------------------1------------------------------98HAB****-*NP3--v*ezi*Y*s*A999999EIKIINN5EGCKHH8FFcM----------E32411-2222-42411D5-dGYA-422554664523112--41C---------------------------------------------------------------------------------------------------------------------------------------------------------------------------4--------IE*58****ARGCQWIucoTeSuTXeRGIEKGHKGJGZ-haXbbUinMON2OQPHDEFIFEGLcP*qjCEdDCFG879aWaaaaaaFbWfB7sJHHaUSKKK3399AACE8AI979AA975684g**kVSneYQ******jigha***tppomOk*u*fzoy59YYeKcTIK*QJIZGJ*ENjLiWJPoRTXVSdIMKZVPPMFI6968C7AB7WSJRLKNUSQPMPPZbC7TDUD7A888B5BEDDCDABDML5EMOLUU9*R**i*y9x****k*****r*w**t**--5LPPK211222obNOQmNWxywaqrthX-rYbiofpcnltsnZXYaXXejiegORZhhZbeghehifakacecUUSYUVWA1bimkmpnhjjmh22DODDDCBHEGHERcKVWRRGNEDFMC9GJLQmiooiKtBGbn*psmqo*lvYk*neQgWZ212313211ESegiPRRQRroejj**********NNLN-185FF88EG--------11-----------------------------1-1--1-S*Hl -1------------------------------------------------------------------------------------------------------------------------1111111161-112-1--11-11--1--2-------G----7-3-------C4------------1a-----*---- -----------------------1-----------------------------------------------------------------------------------------------------------------1--1----1--------111------------------ * f.4 Transmembrane beta-barrels
[  67] 11-1111111111111-1-----343346321-243331111-44-233252321113222112---1 3441211211111112211-12--3111111223334355-1111112----112-----331123335211111-11--1-1212212224-222---1145411-2----------------22-21211-421111-1111-9A68556335533444345234554143211141211113------31334343353444444142112424222143311111111--------------------211--1-11-21111--1-11-12---------111---11111111--------------2211-222--31121111111213-1112------1111-1-11-31--1--------11142112-----223211--33422------------353341-4131-1---132324232342252--1--323111111111111-32-----2-------------------------3211-1111-233463-1111113422221242233341411112----31-1---6-11123---------5112-5523232165112-112221133----1-1421111-----2111111111212452232-334423433222223633344255465--11222-------1--22-1111111111-1111111111111111112111--1-1212111211121211211111111--111111111111---3---------13434---------------22222-22244-222212123212243112111-1--123234111114645522222222221111--4-11------------1------------11----1---1122211111111111-21 9423A5V-NB6164B76885AA9A98966442456654444447767766658656753787964366-562646662666566662447A6687BA779856FIB-9*J**********************D*****************************************q4qnf*TXTH7WYS*8oJaa***** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-1- * f.14 Voltage-gated potassium channels
[  68] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------17-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------ BBMb27A-B--------------------------------------------------------------------------------------------------p--********************************************************g*mr****h---54182B6111---3-1ces*- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.60 TSP-1 type 1 repeat
[  69] 332231BFKJJKJMKF2A664741H66594B431--------1131111-664-11121116442-56 DFS9qA6DDDJ577SbXTT-TcAAw*TSTTTUbmonep**9eKpeIKEAHD8ROSGDG22PMXDxGwtjfH52225752116O22422224315221111A1A1S4D9511111111111111465454655496BEEDD222FGHA8F6662245111441444GHHN931111311111189699A82G6LFFGFGFGJ7HJIEEHIGGGJGFDF8956HIEABBCABAG6BCBBBBBBDCCBBDEBCBG74C1CH1B516KM779EC5797D766546454587877777777868444444444444476666466665836D887A77A6769F2232322-3214221132335235246665215C7LRHHL22222MFhVdC7GVMMON9ABBAAB799G1MOOKMTHMGVV2WTTKdZaYcdYeMRATBGFJKGLMLCO99999999FJM878EG222222222222111111111111122225BTOG76D9AHaZbdccWRPRPZZYbVVUUCOdPgLkXR14EFOAIBECNFLHPJAEE1445C6456556574BEA7769222312442221B99565645FHKKUY89411112222222223222221111167986GDACAWEC8A99B8F8AAA699A97A91128754111111FIDG6GGMKKPMOONLM-JMLKNKMKILJMKMMLMMGQTMLNDA8GFIBHGJHGJGBGBBGQBECFFFI21D99999999999111833233766659EPH444925124431351AAD9J6C7D9K6ORRQGSQNHLMLLHMKM522425222189AD555459CAABEGIGJGGADB74441136BB779A111111112111111--31--111-1---32-----35333364548A43 3389**F-UC7-7AP***x********ZZTWUWcbTZZXYVaZSRR*yu*****x**ybbZaNJcCJJGKFJUGRNNHMOGQRQPPGHGy*j*XmXXUVMZFQWXU-N*b*WfQVYPLLFLLaIdfM*K**c1mcvNMGJSFKdGJLGCJLNKaJeNRmVWNCaRVXJOhWHMFTDSSI*GCGPVz******LP*ysrT ---1---------------1---------------111-1----------------------------------------------------------------------------------------------------------------------------------1---- * b.35 GroES-like
[  70] 22212343444444433343323143363435----1------2325425875146344433222255 DKS3G867777655A5455-5844675555568666B7AA35457A599674FDC47A33A6G6C9BVPL434336443231521411NNWN2E77411HUJJFjGRES22222222222222A1112241126389989111I2CA847789855B86678665CABB948364348453499854553646HJJJMJIKFMIIJII866665IIH6887678777796GA8444444444444443443458B589557878966885655674876666545655666666666666666566666666877556777664547CCCCCAB9DA38333AA4842446343134221333224452444J2IFFFC33323757533334343544444444444-7687666556436666ABAA68A855A9A6867667866555555555AA853B33322222222223233234121222222217575456656999AA97AAA96675BBBB7AAA7555644667895555667744485535F54444444556665H23241321511111454346422KLGIqd26222222222222222222223235444HE6C5CFCEC5OPPPPMFJOONHNLKUIMR2-6845411111169696765666567655-6555556555666555555666778685655555555455555C555555532866677857777224H33333BBCC55J55555333433334333998D9745564B778777B8646765A8A53434534357CA9CCCCCEFCGGFFRNONNGLM6666324288779A2222222252632332-334231222225322333357554343332HHF 5522JIV-*KJ-ikHPYVMOLLHXLVPFFCEDDQPLKMMMLKLCBBFFJTVciVSUZGCEEE9A8A988977C8C98488799878556EOFYlUZD9C9CAELIM5KzO**********************B******************************************AQZG*BBBKBNJTnKKbUujXYeN ------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------2---- * d.92 Zincin-like
[  71] 551312-1211-212-3-556564F3449-6A----1------111-9--1---1111-11---6-41 ADE8*339BDG22223311-18111V11111198889HVVFeE*erZ1PSL8hZf33E22JFWCjBZpreBLGGGQTQ7---H-----879725121--2D163E3H5H-------2211111-11223211431GIIFD222SA77875573422211332434277B912-11113-1-1MM997KJ-JGFFFGEFDCG9FGEDCFJOJJHFFFCBOS6DCCBCDDBCIr64444444444444453278GBC5DD5E74AIICCAE978EHA988DCDFDBDA99AAAAA9AAABA99999999999999CC887CCCFGD7Bw6666676D7ECC336CBEZ8882D2I74885A95S448FBFJ56952CFDD412212H6***63AdIdgPOQPUNPQLQPl-CFiDBrEXJ*2-*ssk********XbC26STZOKNQSJP33333333YJK35E4H------------2222122112222----44A582JYSJUeimlpgQLMMKcc**TQSRIVec*QdcN15WXWf8PKNbcmSu*8BB-5-3DA---------1AHM6HE366C87JL779345471831255545b2M2--1-222222---------122--11IIR88DB1C5L99AAC48A9893668638C---2212------ZWXTBaMQRRRQSSSRP-RPNSTPQQTSRRRSTOTTQoooUVBEDNNKLLMMMMNLKMKKKlLIKJIKNC-YcccccdZbddd---111111223433TEYAAAE8G27898ACGD------4232RDCCCCBIHUCHDJEBROO---------1DCDMHHHHHIIENN98BBBBB99A2222--8C------65556544437----1-1---1--2221---21---CEJC68SAD9-Z22 ----214-A7y-24B----------------------------------------------------------------------------------------534-8iB*******kaefi*h**b*m**w2*p*Yibf*dhrVSjbeVvWR*fhav*BIGg**aXiLO*mt**-41-------EAB*-M41-5---8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.93 Periplasmic binding protein-like I
[  72] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1K-2-1--11--------1111-------------------11----------------------1---------------11-----11--11----1-1-22-**********************G******************************************-11-7-1-212111-1----122- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.12 LDL receptor-like module
[  73] -------1111-1111-22-2-1-511343212----------2-215--33--232-2-22------ 64E5M8CCGGG95987A99-9933BD9999989999KNFE3H9QIJFEC977ACF38F22CICAQ5GQRa78999898G5XF2222117853-435B--3C755E5D7A1111111111111127568B97B988788AB322I1IDHJAAB4488D899B99A8FNWYC6C777869676755822D83B39AADADBDE8CCDCCECEEEACDFI4579DBBEEEDEEHO86666665666666675456MK6DKLE4JEQDD55RT96467BC9B8ACJECEJDFDHCEEAEHBDB67766677A7766FKHGGCEEG9H8DCEFFFFIFE5F9HCHH5CBDV99KPCFB2-TTE2225322BBCF67591588854545674HHGD896GBECBBBCBBCC8CH-IJOIKHMLAM74NIIGLOENNMFIFC67687HBACBFBBCCCCCCCCB796AA8G222222223346446746655544533521468236997DAEEEHDB9AA9AA9ADDDC8BC8BD8B523668C8985A798D89CB4B48A636447448789A67573736648722213635567383363BF19756454444442133333334523488BA8B63A386A7899787778889A8E978--74984222222C8BA78A8AAF8DFC88-A8888898AAADB88888A99EFIGKBBC9BABBBBBBBBBBBB77A777853GDFEFFDCDDFD11422432279A742D6E7567893787635595667667448BGBDDDGHBC9EECC4BCC6545475353988F99998DBEDE79C9AA999A44443293884444--------v-D221261532366366543935533365C767A7872725 E9PWhYR-zQBCiieVbcWekuh*zziRRKNMNkqePURTSTTLKIkgk*vw**jZpecWVWVMLCFH4MHANIRGJ4HLDEEFSLCFFc*JbciXQORZMKaomU5P*j*p*o*y*ecjfdha*xU*Y***1*o*YcedyZf*qWdWdPrcW*dpZjtc**a*aSf*in****yDSNG*ACDTJ*xq*X**OU****l ------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------ * f.37 ABC transporter transmembrane region
[  74] ---1----111--1--1--1--1-------1----------------1------111112-------- -------------------------------------1-----------------------------------------------------------------------------------------------------1-----1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-2-1---- HDHOhbp-*PU6UXaSRSTPWSURRLRSSMPMQQPNNOKPOQSPSPQRRSQPSTONRNRRRQNONNLMBNIKNMNLOFNPNOOONOUUVLWMRVWjVMSQGLRswm3**K**********************m******************************************FoXX*NPIZd****V**Wk****t --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * g.50 FYVE/PHD zinc finger
[  75] 11------1111112---111---2111--111-----------322---311-------1111---- B363z2A3444FEC**xgg-fTBB**fffefebZbZ****5lhf544439335BC64A22uc95*n*ft*G-------2---3---1-3332-2--2223d343*3545333333333333332---12---12-45555---*2KRb1ikg11111111111212pX*8111111131111334331-232*99E9EN9QB9HERa957RRdw99m455G844444444*3266666666666666377432-5-22-1---3F111111112211111111711GA111311221111111111111111211111211112-4C4433U43241x2II----1124-3-2--656--51---11311-15-64222222228BE3*4237W33366666655663-6656656374226JHU546635b44O32333E2222232222222222A2223242222222222322222222222222222224583223223FKKHKk*OZZPCCCK****TxHDDL3J32333V23G22M355K92242111L3222222222F33222113--661111--3231434224454*i-22---------------------11222DK23983344434333R43333333333641-44322222222W4h8458444O4PPB44-446455B4AA4BB44444566CbE**9444445444445444594444444228EDEEE8888E822235857A89864Ix2e222222222222222DCCLD2A222nUnrbn****LRVbV2*i*2222222221222M4BBBBD32CC55B555544422221111222221----------111111-1-11111111211331-------------2Q43 331154D-K9C-GFsro*p********Zadmlm****xlwrsvVTSzt******rY***WWVAA99B66AC98A9CB7ACB99998FFFKRFoJdCAABBGFXLGJ-JK9*SkkkdXJKIBLIITaJVL**Y2WLjFNKGJGINKEJIAEKHHUPeGLZTdn6YMCGWCFlXYZR5746*75789GQcR*VHBCXQRQC ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.43 CoA-dependent acyltransferases
[  76] 44314353334344332243443272265341--2231----13231885BBB2121--1-3221143 AEi4D53488643369977-7B2298777779BCCCADFF198H442-4---4451-2--8955H46BGG934442441-2A3112--6684-344---68779E9A89--------------3254846236B7NMKTT---T3D68A56C22111114227652GDBG1211111311116544444333533333224232322123555623344453--------H6211111111111111111112-1-11---------1----11-1-1212-1--1--1----1--2------1-12111-1211-------6563622222223242244434426611513125512261132---4-23B1g455311111199IF553AA99C22222222224-ABDABB9E5D5583346899898565568I97EBDCF4C2222222233415975-------------111--1----------153131354351114112-111335621111164B8895--4425B2218A71B7--7699A32-------222752AI836155361443253613326A6575Tn351-1-------1-11-1-11142267768856986476655677555BA96678C667---3426------25121415445554A45-434464545345444544415523114213131312323311314333323--288778878776---6-----6656C4J14111-111-----3-411111-4-215666665C9875756496732333323267CD74445468ABA34344453332121111888778855555555831------------------1------281-1-1-1-2484 EH44tnk-XA98CBCBADBEDCDCC9BDDABBDCEDBFCDFDDEBCBCBEFIHOBDBE9GGG979A89488998999599899989AA9JKHAHCMEABBBADBCC4U************************A********************************eKLIPg***a7WLC*CDBLEihhnFjTJHLJLJN -----1--------1----1----1-----------1-1-----------------------------------------------------------------------------------------------------------------------------1-----3--1- * c.62 vWA-like
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gdGNYYRPSSLPPSTTIPUUOTTTUSSMVTUPTURSRQPUWQLRPMPSPRSRSUPVTTTHSTQRVUPXHTPTVWVSUcYXPeWPWTdOLQRQUMnnxJR*S******yiZviw*n**Z*g***2***deYY*ip**Vpomjxfl*qnlrvVZZdgckM*ehuPYjRVeYs*beZgZ****R**Udasnla ------11------------1----1-------------1-----1--1-1-----------1-11-11--------------------11-----1-----------------------------1-----------1-------------------1-1---1-----211-- * g.41 Rubredoxin-like
[  78] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------g----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3355bYF-TBE2ACIUYrLBFEFEGDHIHHLIKHGDKJDHGIKFEDjRJJPSQXCILJKIIJS78687397984989688699999887f*cYk*j56AD889PnT-N************************j*********************************w*******h5rU8U4359J****c*iGRJMMNG --------------------------------------------------------------------------------------------------------------------------------------------------------------------------O1--- * d.42 POZ domain
[  79] 99A9BA88BCCCBDC99999888CG89DCBFD89A784667668B5C797EBFBCCCEEEF544D435 6FL4E638AA993786766-695598666666A767ECEF3LEHHG8937726AD45411EGC6GAFLLG84111866346DH73567KONJ-K773--8D7ECM9MCK33333333333333498ABD789IB7AA9FH346MCGJEEBBA9A88647586986GMLGC275122272312NJHBBAA979FFFNGOLONDMMMOOMA9HHEILKN7A9CF9BCDDDCCNRAAAAAAAAAAAAAA9DDGECC6B5CD65655DC77FC665857ABC667633385555566545634333333333433398888588864DBGI7778988E7FCEAA8DDCIBB99D895778EB7959967985B5AH7VA99A23332AAMNRC77DAJEC4444444444C-JJKGVJNGBJ73FEEIEIKIFFHH8A9B589C9A9A7AA44444444BAA548G811-11---11--------1-------111178C72ACB88EEEEFDEBBBADDEKFEED8EDJCEEEF56DFDFDBFCFC99I6788B423B3334323332377ADFFB97B85B75563A99C898BAKKQLkoBA743362333223633333335656B75AA98H9B9A8DCBBBB89DCBB9ABCFAGF1-5985B11-1118999686ABBBABCE99-C9B9CCB9B9CCABBBABDAAACC788BABABBBBABACBAA99A8787697297776A978766223445434566685O7B888788566656446B998977686D8999A98ECABBBBAEFE3222222225BAAD99999EDAA9AA87878A892222458B99779933333333A3411211-22122122223122312229B99A8B8985BB7 HHIHcbc1*eYRMSSRXbXUbiYcYaZYVSVUWZXbbYVXVVWSRSUVYdcafhVWWVUVWUYMOJIKCLJKMIMPMGNNJNPQOQNKLPjQXYRbMKKIILOfYh6k***ixYjdfWQXRTVTodTwW**h-rV*QTTQaRUYROUTTTTSQpTSXYXaciWjeQUsWeht*rOJbaX*QOPoe*w**Z*xcj****r -1-1-1-3--------1--3-1-11----1-----111-1--------------------1----------------------------11-----2-----1-----------------------1-----------2------1------------1-3---------3---- * d.159 Metallo-dependent phosphatases
[  80] -------1-------1--------31121121-------------------1---------2------ 212-O--31111--PnhKK-Kq22lgKKJKKKorwsRGRc2PEr2-1211--3171-2--SH8-aBaaISA----1------1-----------------1-1-2-2-1--------------------------12221---D-B752772--1111131131-446A6-1-----1----32411---1-7333336644443444226638333----1-1------2-1-----------------1------------------2-------------------------------------------------------1-1111111-1---------1--------------------------1-15443-----22IEC11-739A51111111-111-45855757389-344577924332213822922233334---------22-----------------------------------6GI6--11111112511333344253333-44162245--22121-2121423-----1--2---------2131-----------------------------7O-------111111--------------------2---1------------------------------------21------------------------------------21-3------------------------------------------------11-1132-----------------------1--1--33232221-2---1---2------------1-------1---113333---2222------------------------------------------------------------ ----jt9-842-99B************ddhhff***gjeigjjfaa************phifH893533A3394A3323339AAEC222*******55587ILetn-8n********xnnv*****z*****-*y*ky*x*yn*xUllyu*si***r*****k************5bLC*B9ARg*******ACdUXcA --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * a.104 Cytochrome P450
[  81] 665465888888888749555556B77989C6EGD888888886766568A99B9A9987A5555-55 GGLCKDDGHJIADADDDCC-CHAADLCCCCCBGFEFJJJHEKEIKIIDFIHETNREAI88JIHJKJMMMMGDEEEFDEFBBBK9A999EFHH9J994--AECDCFDMBE444444465544448BBBBBBBBBCBLLJLL555MJBEEDEEEABAA99ABBABBAFDDEFCABABCBBBAABOHFCCDD9HBIFGHGIEGKCHIHEDFLDHHEHHGECFHMIFGEEEEFEHDFGHGHGGFGGGGGGEGGHIGKDHBIJDHEEEFHFFLNIBFGIDEFDGFHGEEFEEEFGGGGGHGGGGDEEEEEDEEEDDEDJICCBIHHEDIDINKKKKKKKJKLHGBBEKKIDFCIEGEDD9GEBBACGEAFHHFEFBDCAAEFFF78898DBKGHBABGEGFFEEDEDEDCDDK-CBGBBDGCFRD6NLLJJJMPONKJCDCECEGLMIKNKFFAAAAAAAAIDDBGDCE984443444455555555755555554559BDCB9FGFFGMMMNMLMJHIHLLKMNNNNIOMLMFFGFADIJHKFGDDJIKHIKDDEBFBDEGAACAAAADFECCDAEGDBADDCBECCCACBCABAAACFFFFFGAE9C99899999A88AAAAAA899888DDIHKFAGCBFCGEEEEEDHFEEFDEDGDDFF7-ADACC35-656QLIHLMIOQRROPTROO-PNOPPQRPURPPOOONOOMSPSHJIHJSLNONNQNNOQPSPORMNNKOOPNC7KJJJJJJGIJJJ678BCCCCCAAAACCGHHFDEJEH8CEDAFFEFCCCCCAEABBGDFFFFEIHICEEEFDGFIFDDDCEDDDCFGGNEFFFFIJGHJFFIGGGGGGHBBBB88CIDDCCFF77787777863--2-4-1-3-2-11112311-1---CIFDCCHEEECIEE 7534ACA-LA7289DDDEBDFGEGEGGDEFDDDDCCDCCDDCAEFCFDDDGEGDDFGGDDDDBCCACC9DBBCDCDEAEEBBCCCBEEEAHDDCEEECDBBGCDCD1AdBJDJCCHD7986898GB9G8b*C-HCK6979B89E868B86874B8887EBGJBICA8KABFCBI9AGPK*HEDKHiNVnDaZABJDDGF ----1------------------1----------------------------------------------------------------------------------------------1-------------------------------------------------------- * c.72 Ribokinase-like
[  82] 553624AEFFGFEGE94A888B8LC77C596CA7968777768657A656566559354446666-65 BHK7VC8E99CAAAMONFF-FJ88IZFFFFFFNSMUHObaBLMXHHHC9GCCMMOFFH55JFL9JEYUZRC8777A773474I88777CCEB6H661114CADBIBIEF22222222222222467666676786FEEDD444CAD89A8888877777678877BB9F9566665565766EEA89973IDKJJLKMKKMFLLMKMLLIJJKMLLMHJJDJFC888888OJ9CCCCCCCCCDDCCCEA99DB3838B38232A97798685896A9B4445444555699777775775555565545555576556666B6D3CK55556559698ACC8665A5675F9694MJBB7E7996A9B6124I9CJHHD23333JEdTSGDGIKHKLDFGHDFHFFFM-FFSGGdFUSRC2VOOMNLPQNNQRNQCADIGTIHJKLJSBBBBBBBBPCBAAEEB33244444111124221342142242131ACJSE7HZSGXccabbbSMNOLaaedTTTTLUgUrOYSQ8EOMKNJLJIPPUQcS9BH8978DE6666666AB9POJ4KGFBAA77876675HCHAEAC9AHIFIFI9D956665445444645554556669597GDEIEBGCLHHFEFGFEIEFFEEGFEEDGG323CC69443444MJLJBKGOLLNOPOOQO-LOMONONPKOLNLLMNMMNRURNOJHEMIMLMKMMMMMLMKLLOIKFJJKMB4HIIIIIIHIIII55588888788888HLJLBBBE8B36766A88AKKKGKEIDDDO8RTRRKRQKMPKNRIGDH6686777667FCEJFFFFFHHEHHDDHFGFFFFH666644B8999ABB2222222233411112-113111-1112241211112474475677AC8B 453366G-UDB1CDFZPUSSRQOchWYFFDECEEEEDFBDDDEFFFJMHOVZleJKOHJNNNBCC8AA6AAAD8BKE8LFAAAAAA8A9ENFPBKAKGIDDFDHGM2HgHVNPHJJKDCECDHEJJESEd*G1KKOABDBFEFLC9FBA8FCELECGDRHOPEOGEEMMWQJQM9LKMD*DCCEFXUomPTHKLUKIHQ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1- * a.100 6-phosphogluconate dehydrogenase C-terminal domain-like
[  83] 4423627387887AENH8HL966943342534222462343435525E3393468658A463227-22 6DG5555444444454455-55445455555464445444965697457666AD84441155B4845666444446562242588DID549838333114766686C66222222223322223336697556C57EEKI---48KCKJFF8AAAAC67965AFB7EELC5555555555552348A54258778889899899989A88777788AA87679766666676566565555555654555553323443333433333333322232333333334334444444444433333333333334333333333HB97J777878897A86BB5334A7C337BDH89ADADF8AAA889F533CBJDAAD37556BCHIKB99MNFHL66666666667-CCICGJDJA9B3CCCDDBFCBBADD6DAACABJIJJBAC7777777788856*HS333333333333547735B5435533333477BC6IFEFGHEEILHIEEEEFFMNGGGJCIFKQJLJP67QMMUDIHINKIMDIHIVJFEEUD7777777EFBCUkGPH7C8INElbMML6VIYTJMOFMLNLMDH7955582879C57373333333C98E886OKFITRPDHJEJIHIIIIHKJKFIJJLFNM3-8EHJM333333LOPPKLIHJJGHGGGII-JJEIJGGIFHJGJGHHFFFCDCNNFEEJHHHJJJJIIJHJHHJIEHDIGHHC4MJJLNLIJKLNJ338E65656A9A9AJbEL88897869767B778EEEDE8CDGBJQVVVUNRLRRLLMLOMMN333333333CJJIJLLLLLKLMMLMMLLLLLGLLAAAB44xFDD447689AI8GI785333333-333332233333333333395677758766C44 5634XWL-Q884CCF87778888897788888888888688888887888998A988588789888786789677885898888767989F979CB88886D9AB73RSI*******rclgqyq**r*t***E***irnk*pr**brplh*nc*o*uvqYz*mbU*UYRXqZqaP9EFG*EGFCFQLRm7VGDIHKHII ----------------------------------------1--------------------------------------------------------------------------1------------------------------------------------------2112- * a.24 Four-helical up-and-down bundle
[  84] 441-1398DBCCDEAA12443426F778336E111---111112112212322-11111112332--3 466BXC5EBBED7Bp*oWW-W*EEqtWVWWWf****s***6mHg8A9E9776MHHEKI33QTd8NLXTWUH333333323A8A33344999D28552--AIEF9FDCAC22222222222222346468444454ABBA9333A54333338223333333333268953333333333333FFFCC115I6ADDDDDCCEBDCECCC6B977ACDDAEE9C65666666D96999989889999899899B82646647242556666674556556666777657755555555555666666666666644455544464686C4444444444A38867635A753B554288677A37865483152D2BZQTj45444FCsaeHCBgVmfaEEEEEEEDECE-GHRGHaGLFLr3IFEHFDKIGKIKOPJYOLLWFDGFGLT33333333G5447HJE111111111111111111111111111114TNXL5BhYMfOJJLNPLIHHHFEVTKJKJCIdMjchok48NNLHCEMMUNYUXSB9M4353H95554443334GIMBbKHB9A84697693FIFIJ9DFJNMHNUP9A887324454444444444443553933II9GQENGNOGQSTTSOVXSRRTSRXTRWT2-45A74222222ECBC7ECDFFEDBBBDD-FDEDBBBDBDFBEBBDABGDCDFBFCCCDBBCCCCCBCBCBBCHBBBBBBB51DCCCCCBACCCC222G8888888886QNDH5557A8577765887PPRRPINDFCGCeeefSaUWTSPTTQLLO8444454444FFFLDDDCCEHNGGJJDEEDDCCC67772238IHGGLL--------415-----------1---------1---44444242222A6A 3111GIB-H67-BAGQWbOhVTXiahdVVPQOPNPNLPNPHNPRSQMUNPVMbULNOGKKLKNHLCCC7NAAIDJAA78AELLLPL567KSGWQSOEGFDBHMVbT2KmA*LTHJTIDFDFDHFRPEVHw*U2WMUCGGDIEFNABGDF9GD8HCHDEGHOKDpH65F8A9KVHc7HH9yDDBEDjQctTTb8BGHMMA ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.38 Thioesterase/thiol ester dehydrase-isomerase
[  85] 554354887777767837454453HSKDBDMC455444464449D7A735E9A4464956785632BB 8ER8c65FDED564mskRR-T*BBmhRQRRRb****nh**7XNfGQIG6AB5RNX9BE33TJT5QIXWaN722222233222A53555554425543114G5IBNNK5O322222222222223DA6A8D9B8ADAAA88333C6OBHFCDA58CB7677868B7GFHPD6664666664667789933465599A9A9A9699998A5866469995858956444444JM2444444444444435444732323323222332223222221111333333333322222222222444344544444424422244424558866666565566666633354633A435434456433255564322K37TBCK343348GVHL757987C88888887788B-GEHFELIJHRI3IBA9JHLONKKN6CBA9BTHB889F8FAAAAAAAAC887A6682211111111112333224233223221247b*B3DOIFGPNPSTQGKLMIQQSTOMPP9LaKkJVPI57FDIFI997EDMBULAICFBBE77555555567C8FHF98C46464645542A8C658966DCJEQU38422322222222322222227246H9BB88CB9B4CA6A9988897798686876772-4A88C-1-11177774879AA8978789-989A987AA9A7BAA9AAAACB665949789999999999999A9877768535878889888783349444446777BACAA666354534324664JIHGI9D47487GGGGDJDH8DGDE8BCA644545544C677988888AAABCBAECECC98A66664484IHBBHH11111111225----1-1-11111---1111--1115435454544791A F*BGPOK6fID9FFWGLHCDGHENFJHCCBCBC9A6ABABBBBA99CBBEGMPP8CDDBAABFBB9BB8CBBCADBB8BB9CCBBCBAAEWFLGGNDBDDGEIPMP5dz****u***dcXZddb**d*W**y7*n*WfZZrZhtYVfbVWiWX*bpigqNZuSUKQGfSSfMXUKHXPN*NNJSf****F**NTt***Q --------------------------------------------------------------------------------------------------------------------------------------------------------------------------21--- * d.129 TBP-like
[  86] --1-----1111111--3------5--22611------------u-1--221---1-112-----2-- FBQ-*--1---1-185566-6522986566667768899C587L7H81687-462--5--HH79QAIjpk862333AB3-255-----nl*s-O44---BV1E9*AU3c--------------121-421-21215998A1--L-424222922112223222211444622232223232232-22FJ-2133333323211226632622321181311-23566552D*-111111111111112--12733332322343322662241224223436979611BBB88DBABDC23333334333323882227773I41C41112122-12i322-eeGS2j2--233145C2429--112-N---8-E6662-----22-1-1--11141----------2-2232212322--6224653766362-1--23-3-333312222222211132-1--------------------------------7724----277778785665666599985786A1343--5574221-4--1411-6-21121---------1-2131121112-13----2222123----3-IL-3-------1-1-----------1--1--5227-*C1E18E233363344328324248--3223-------12253113333333333-232333334323334333135356222-6---1----------411122231-433333333333---2---------2-U311111221----111-3232222---3p5555123521---2222----------566845555783ACA9JGFFDCCB6666---2IF3355--------1-------------7---1----2----2-351E4CCG-iM3 DD69bbU-M574ACCQOfVYVVMiZdYDDAB9BBBBD8889889AAOMLRkk*rRTRPKMKL98B6763945B8C35345698999888COMOHPF88A8AKCKFF4O*e**********************D***z****x***o***z**r******x*****jXzZS*Z**U5W*HuBD9FOls**e*qHUSXSSK -----1-----------------1-----------------------------------------------------------------------------1---1---------3-------1----1--11------------------------------1----1---23- * b.18 Galactose-binding domain-like
[  87] 22-4-22622422226-2222224C4648888-22333333346646644A6644444644622-2-- SKg4S68AAAAA68*WaUU-UWAAnZQQSSQGUSOUKMKO6KGgC8887C8498869822EGM4G8ALWK8--------2624AA8EEYacU2b8E2--CbESKmSiKP222222222222228A48AAC88AIC4445564444GICCECC4466666C8A8E6UAGMA26222226222258644444888AACAC8ECCCCCCCC6688A8CCA868A6A8646666GE46666666666666684668-242222-22222--22--2-3------------------------------------------------4E28G222222242422884446424224468466C66688242227484U8YYGGQ44444SYsjygOemgkcWCEEGCGGCECI-ouabsimkCMW2aMMSQQUQQOKPOiIOQGCICECCCACKKKKKKKKIROMIGSI44444444442242664664446644244688IKAEGCCNYgigiUOIGGGVUceOOOOGQcUgWiho3CegaIeMKOmYQIOIOYaOVMQIK4444444MHSUZcISOECFIEAITCC84ISCKMOSKMQSOQcQ6QIA8668888888A8888888KC8CMMSMKCeaSmWaUEYaccaccqoccheYo*mqg2-4SOGO------IEEGCQEGKLLGIILGG-GIIGGIJGEIIJIGGGGGIQSQIG8ACFCACFFEFFFCAFADCMEACCAEE4-KGGGGGGECGGH224Q8A888CKIKiSWGI444466444344664IIKMICM666OOUWWYWUaaSaaaQOOSU644444444QEQQTFGGGGMWaUUacUOWOOIMMECCC88OIQRCGOO6666666684-----2-2132211222231122111664AA88888KSE6 336644D-62---2122232222222222212232322222222221233333323333333222222222-22212-22222222---33322242332233433-1h6*ONMQUCIEDAGMHNL9TCt*Z5ULY8FGEIHJNI5IFGDLBASGJMMU7Dc6fLFABDDfx*W7-438VACC42B22P24266K9D6J ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.35 Multidrug efflux transporter AcrB transmembrane domain
[  88] 55251456AAAAAAA56H776778F55I9CC5D8F769A888BBAABC9BDEE98A8864A5768-68 HM*9TBBBJJMA9ACECCC-CH77DICCCCCDHGGHDMdbJEDKaga99NIEhchBFK55NHEFPDQQYOC988899978A7E77666CBJD5U772447H8FPSAkCV555555555555555899A9689AE7EGGaW778CBCDDECECCDCCCBBCCBCBADFEJEBCBBCBCCABBCFDC99FF9GCDIIJIJEIKBJGJIGIYLGGEHHJGDKLCOBBGGGGGDKsBBBBBBBABBCCBAB9B98BDA349C48664DJ56BB699888CCC8889666967988999897984555544444454988666777AED7BGAAA9AAACAB9DAA9997HD965C99BAFGC9BBA8BBFEGE539FCkIEEE47767DAHIG988989DAKLLKJIKKLLM-FDCDECECNW85eUUMcefjjfaWECDBBIQHECEENKK88888888FFH99E76333444443322111111111111143435BELABACAAAHHHJIKICCCDIINOFFFFBFLJPEFJD55ECHNA8EADEFEEL88B7978D999988999B96AE3DDB9DCBCDE9998BDC9A7CEEFDDFBEDG887779A99A99A99999998789888EDDD8AC8FFFCEBBBBEDCBBBCBDDCFF3248969644666MHEIEIDJJJGJIHJJJ-JJIJJIMJJIJJKIKJKKGQPPKKGEDKKFGIJIIJKIILIGGPHGFHHHI84EFFFGFGDGGGF556877777999998GEN98997C77785888B999A977788PCGEDEGIEJEHGJKDGDE8444375446EFEIFFFFFGGGFIBBCCCCCABC666665BA88AA9922222222335111-2-1111141333112112---5BA76BBCBD9bC8 331186A-I9558EFIIGFKKNKSNQGCCBCABBCDBAAAA9ABAADAIRPSfQIJGDFBBB7CA7A9878CC7CBA7AB899989GCEJWHIIINXPPFCCCGFI2DaATGOFIFABB789JBg*7XAZ*D-HBZ3B8AmBALB4BAA6B65M9B8EE7AEAMC47D75P67I7IGEF*A9AEFkSkmHWWNPRZQPO ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.81 FwdE/GAPDH domain-like
[  89] 5527248776866865499B97899767A9C9A8C9A99A99ABAAABAAHGD878446359555-8A 8DI8J97BAAB788BICBB-BF88DQBBBBBCFDFDFNQW8DAEBE987886IJH97833FGE7EHOGKHB65556664588K76777888868442443B79BD7DB9334333344433337AAACB98AA8ABDDFE889EJECEDEEC8899889998AAAAGEGB8977888A8788DBB99B97ABDGGGGGFGHCGFGFGFECDDDCGFFCDEEBA9BBBABAIH888888888888888A999B444755774449966565456957566666444B88666666666663433343343344B989987775BL9DKCCCDEDCADBCDJJA666G8965DCABBEFDBB8B9ACAABA558B9EEDCF47757IDVSTB9EGHGGEAAAAAAAA99H1ABLCAQCKNL83NHHHJDOQPJNLJGCC9DHIGEHIEBI87888888IBB7CDBC444444444434545545555455454557FGRD9IVQJUKOPNOLKEEEEOOPWHIHIBKOIXPXQS8AQQMFGHGGQKMHXZDCE799AKC9BCBBBB878GF98EMDBCECDGEFFJ4CCDBEDCBCCDDDAOBH877666566945855555555977999EDHEDAHAKFFDEDDEDEDFFEFDDEDFDD343BC99454445KDDDDFDLKKJLKJKJJ-JJJJLJIJKJJKLIIKJILJMKDCCGDJHHFJFJJHIJEJFFJFIEEIIIHB2EEEDEEEEEEEE55594444489899DGFH555A5845656767AHHHGHCGAAAL8IIKIFKKMFIFIJFHKJ7777787776BACDGGFGGEFDFGEDHFFFFEEEAABB668B996666222222227321-1-1-1-11111111112121---36722968889D84 68--56B1OA8199CQNQNMOPOZaaQHHIIGIGHGHHFHHGHFJHIGIRRYamPPOKJFEEDCEEFDAFDBDEFBD7FDEDDEDBABAGMHNKGIGFHFDIDONO1HPEwLVKINOHFOKKIMfXGlJ**V1aSeDKJKULKPGEPGMINEGUNRMMNFOS8LED7J6BK7BTE9EGI*GFCAHih**MpWEJXSaUI ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.8 The "swivelling" beta/beta/alpha domain
[  90] --1----1111111111132111-111212-1--2---11221---11-2442--1--------1-33 34E3C877877565AA977-786697777778778899EB466865123LJ878923K11CB72O7QKTU711111111111712222568618542--34422F43541111111111111142113212323143367444A6V5EF55F33343334332358659O332222392223A643322653433333443334434423445443422454231221125639A7679799889994544321111111111111111111222122111111111122122113233111111111111112211122213213411111112136333222353611533434435433234333311232L987B333338AEEID84A999C33333333333-BCDABFBD4C4163348A88A8375596688369657594444444423344C681111111111112212222222222111125325222222655654535546655645444676455622555A7B535654433493545621121112347576P4422124353222134234224288A8Xb3711111111111111111111311223332452483644667856566666555567A1-2634511-11144443454444444454-4444444444444444444544443424434444444444444444453444154444444444411352222232227592232222222221222222232222233544443234333442435---------13437666665547757547446667645--51446666111212225331111----11-12222--232-33311111111114774 21--654-A44-87A3277446492654467AC9DD756754443424579AEI555533447443332533424332331224444441292237----231889-2*T**********************1************s****************um*******BJ*Q5VWH*777gLOx*W4MGCbe*lrD ----------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------5-- * b.47 Trypsin-like serine proteases
[  91] ----------------------------2---------------------542-------------11 128-1--1------23222-22--4333333233332343-231-21-----1-1-1---421-224132-----------11-----11-1-3112--26255945151111111111111112-C2C1-1J2513323---D-M69766G----122111111258AW-4-1---2----1---------------11-1-11111-1---1--1-----1-------12-------------------------1---------------------------------11111-11------------------------11-1----------1-------1-1---------11-------------1-B2111-2--2156553112222311111111111-22431421214-111-313222341231111-26231------------1-1531-----------------------------11222-153312232252111122423333-33135554-13335222214114-25C3-1-2-11111-111422-35622-5-1-3----1-13111-122226w-21--------1----------1---11122113243231111212--1113-1-1121---1--4--------11-11-11--------1----1----1-1-----12-4--13--1------------------------1---21111322---2---------115-1--------------111121-3---3322321412421221212---------13343111112-23222324224471111--A-7744HH11111111G---------------------------1----------253 ----25S-623-11322312222413211111133322122121112211412211221111----------------------1-11121222231111112533-1k3**********************F*********************************Yuerw****1*T-11111-2121112127622H -------------------------1----------------111-------------------------------------------------------------------------------------------------------------------------------2-- * d.169 C-type lectin-like
[  92] FF8DBEGEKKLKLKKIFCDFEEEQMQMLIFKL88BEFBDCCBDIJEGMECMJLEFFIGGDIB99E667 CKT8R859999666FIIHH-HL77KSHIIIIFOLLMJQbT6EBHD8983661ECE98D22GGG6FISQRIB1111211869FM649679AB74D761--4F4CEUAHBF33333333333333754355445455HJJEI777REFHGGEEE9999AAA9AACEBAJKKE88A688888799IEFBB993DGKRQTQUQPSESRSQSQBHJJEHVTRFJGKHGFEDDDCBWK8CCCABA9ACACCBCA89BBC665885566666558967646476688888886898888888888888898888998889886668889EIDJTLLLLMNLLMJAHKKFDGBFKB67898CANLCDGJBEDAABAD985IDDFDDL34444CEdVbFAAJHIKI6666665666A-NQMKPPMGHKJ4HJKIKKKLKHNKHLAEBKEHCFDDHBJ66666666D8A9CCC8222222222222234423432222211115CELE45A86AGDDIEJE9899CCHGCCCB8BFELKRRN4AJOKHJCCBHGGBIBA9FDDD9B43333434668EJHAdLTDBE88GH9A97DGDEFFGHHIIIIgWLK442234444222322222228455C7786FEI8F9G96C78878CG9885B8CC6GG2-2887C11-1119BBF5C88999899987-987A999888999888888DHHDA7879AA8AAA9998A9A8AF867667832999999989999222A454457A9A9CN8A444957433323346CEDCD89578B7GGGHBBEBGDDCCEB9B535434433D889CAAAAA67BGGCCCADAA888755523D7FFBECB2222222283622225-223222222233222222277688CBBDC9L8B BC35KKJ-ZFAADHOPMRKPPSMYSXPCDDDCDEEFFGEEAEEDDCIFJUKMkTHEGGHHHIBAD8895988A8BAA8998CBC9B9CALRGMJIGHFHEAEHHIG7EdNeOUOTKLHJG8IJIgUFWK**Q2TPgFGGGMHKRLEJHGBPDEYFIHIKOSABeIHAHCCOIQTFBLMI*GHKNMULPdJWlHJHFEHF --------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------- * d.157 Metallo-hydrolase/oxidoreductase
[  93] 33534344434444343344433433334433666444444445344454444533444444342254 2341455555536365555-5544685555567666A7CE344633324445545444446574456364333333333423533343555535442--333433332322222222222222244456444434333433332522222212222121111121322221121111111112222322243433333353343333333445444334543333333334343333333333333333333432255222324433554332223333334334333233333333335455554443354233222333438667777675657546775353554234444378556333354455333242222222222242222223222344444444445-22222222443254444444454423223333333333322222222322224262232233322222222222222222222213653366654555765644444457555545A68668733555554445454444444645333333333333579132244433333332545333345453444355333333333324222222243333444454554455544454345444443544463-1344411111133433534443433244-44344344444343444458764433363656566666555565333333432344444444444113433333444445678434444333333444444444444495556556556557765553333333334444545555444443333333333333334532222221111111112211111-111121111111211122133333333333632 FBGLYYe-yQI7YajXVbXYYZZaXXWcaUVRXWXYVXVXRVXWVWVYWYXYXXUYYUVWYUWWVTQPJRYQWUTSXJUUTPQSRVRUSRkSVVPUTQQNIZTjnk3o*p********y**u****o*t***J***q*zr*q***m**wn*sn*y****hl*n*m*k****ehviKkea*SVUQX****a*jQTViUXN ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.5 RuvA C-terminal domain-like
[  94] 66AA96DDEFFEEEGD7CCCCBB6B66A9AAA8A87978877776575668677AB8B9798867287 AAI8H335555453AAAAA-AE66BHAAAAAADEFFBBFF5EBA7753544488843E22EGA6GDCHGD775556662365845654557848224--297CBCACC4111111111111111544456454B6A77ED333C9C8IC88856785555466A8B88E833534333344685576543689ABBBBABA7BBAAAA76AA8AAAB8787E56566765B74777777777777776867766649746646994477665233756222222223322232222222222222222322232222222225624655564557563855244342423877559786635A566656352D58BCC93333377FFG56CABAD97778757677C-EEFFEEDG8HA3DBBB98ABB9CBFA8A9A9ABAAACAA888888888998AEFJ3322222222--111111211111133336A9EC5CHGBFHGHGIHDHHHGFFGGJJJKCFIHCFEGG4CDDCCAF8AF8DEEIBDCA555BA3544444797CC85888859D6B98874655575787CC9CBK97873634455643333333337856798877E77D8C99CAA99C9CAAAAEBABAAD3-4CD8D22122297EB7AA8998887888-787A988989788888887AAABB8999798889888999978EA88888A64868678868777--48565557788D6F69444555244435454777775A77698HHEJDCBFBCEDE9BCECAAAADBCA87998CCBCCB9C99EGGCECC999666644957777771111111131---1----------------------55544564446926 JJGFOSMCsMGFNOPOPQSQOOPTOTQPPRQQQQQPNOOOQOOQPPPPRSSRRPPRRPPPNNNMOLMLDOLKMMNONJNPMNNNMLMMMMdPPNPSONNNMROWNdHOpT*f*khrgSTaaaaaolYzc**y-we*UaYXlMYbcSWWUYZTajSWVSafo*UlYWX*RbyXavOQPQL*OQPUQyd**QtjYggRNMY -------------------1--1----------------------------------1-----1-----1--------------------------------------------------------------------------------------------------1-22--- * d.153 Ntn hydrolase-like
[  95] -------------------------------------------1---2--211--------------1 89E2y695556B46jeaWW-WOEE*VWVWWUSUNMO*t**1wes2113171145732811*m23*M**i*8-------11441222127313141111-3J332*36151111111111111121111411112122278111*1FLK7QQV1111222212411FfR*81111111311121111111621*66858D5DD6A8EJ623CCLg66M221B412222222*3-4444444444444424422323333332424A333333333322244433733CB33333333333333333333333333334433331227B5555E55354*3JJ21113-731254115571141111111123261C522222222BAB5W2337L35333333333324-AAEAE88678316FEO555645O87H561538343324422222222273244261111111111111111111121111111113343133324EEFFFinagmXAACG****K*EECB3A41256R12B31E367G62172113E1113111143C34915746127843222-B8AB53N3E6656**43233213332441221111212111233891-2D8323988888Q897888978A8AA1-12542111111T3mA357366P3OOA44-645474C4986CB333445538QA**748464444454646648344543411ACADFD8868F8112479687A98A76h2K111141111111331779C718111LMQRLQsuda8GGID3iX*5111111111233K34444738665573433334222211222211111111111111111111-1111111---11111111122122222221K12 218Cjv7-411-44Whf*Y********KKJRPP**zcdadSacJKKzk***xzwiY**oOMN333222133232322122233333697HNCf8L7444244N99A-4U8LBEC67rfeeaf*X*tf*g***5***dgbT*gp*dQkdKS*UX*O64Ll4377F84386CFKH482EL6*S5AIQBCAH*9B547854P ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.28 Acyl carrier protein-like
[  96] --111111111111111111111-1--1-1------2---------11--211-111-111---2-11 12227---11----11211-11--1211111142222A49-43421---121312--1--331-2224332-111---11221--1--222--1-----1-11-311----------------2-----------23333---2-3124-----22---1--1--2424---------1---212--------111111211112111----1-211---21--333333-4--------------------13542241434332222322--21---------------1--3------------------------------1111-1111111-111-221-1-1-----------1------------14533411111112322-12322322222222226-464633431111354443333366112331231212121333333332111212-------------------------------355111----222322-----111211111-4223322-1--12221121--1---2-11-1-111111121--3-22132111-31111--1-11-12-112235-1--1----------------------121313-1111211222223332231222421---1-13--------21--11111111111-11111--111111111111111112121-111111-11111111111---1--355545445343--1------1111-14-3----2----------3333332221--22222222311-132-----------2111211111121113313333---11-1---111-----------------------1------------------------------ 6688lj*-*WSBLNVEHGFFEHHGFFHGFEGGGFGGFGFGDGGFGGIFIGGGIHCEJGFGGGHIKGGGCHFIJHJGG9HGHJKLHKAAANbNHPPQKKMMHHLcYW1f*q**********************F*********************************n*lo****pCQOBxA97KLgVgkFdmCHmkjlZ ---------------------1-----------------------------------------------1-----------------------------------------------------------------------1----------------------------11--- * c.45 (Phosphotyrosine protein) phosphatases II
[  97] 33111-5865565764-4232221B55542742122222222333333246652-2-12114461-12 9CD7RB69DDH769OTPCE-DS44MiCCCCCIXWcZQY**BR9dBB9A4B76YMVFCF--HJZ6JHYRQSD33335551144I3333332342422-1128497C5A88--------------144444434444999BA222A599A8788574433355467769996333333333333A9A78234EBBCCCCCADDBDCCBBAHFEE9DCDECJIIHA8777776G74777777777777779887842325624212564455131354333444433335533333333333344344444444452244322242556E666765776737774554B54316423388474232225322125C2BMHHC22222F8IDN769CEACCHIJOHFJEJIL179F75O8FSXD-RNNOOPdXSdYXHFEE7HNbHDFHENQGFGGGGGGDGE8698C11111111----1111-1111-11-1111BCSgD4FSOGIiehfehWPPPKfejnVUSREU*a*RhcO36JFIHDGDBKHQFPY5572334F84766666364FGA67838556756446-5556658986666DI37433545433321311111114243365EC5BC6Q9HEEDEEEECEFCCCFDAEFFEI11-7643111111FD9B8BAFDDDFDCDGG-DGEGDDDGBFDDFFFEFFENRODCGH8GEDEEDEEEFCCFCECNBB699AB5189A9BBA8BBBB111833122AAAA39FNb555445-22223536PPRNNAJ9ECL3OOOOQUUZJXXTTENKM6332243334988E9AAAAEGCBEABCDCDB88822222233663333--------213----1---1-12-111-13--111112312222425738 --22CDD-E761BEAKNROWSUNZcYXHHEEFFGGFGHGGGGGFFFIFMWXm*yXQKFFFFGFBE8CC5DAAFBCEB7CBADCBCG799MeGNFIHHFGBDEJHEH-AdBgTnTUTUNTNHLNMVVOdS**T-XTjJNQHWMNSHFMKPKKPKfLGGJTNjZDUILFWDHNBNWE7DD7*888CDRLkgPO*BAbKbPO ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.82 ALDH-like
[  98] 33-2--77DCDCEEDC1A21---473384A82--51113322432122379CB736576AE7761-11 MPx4q11423322258888-8711A87777749878B8C9AEBHFTE47632AFL525--FEB6PAKWYEE2333455--1-B22343gd*t1d771--Be298*Oc3*11111111111111245233423457BBBGH11-M5AA9IDE93355334444375BGGN9121111131212272339738146666646A45765676CAA7765414712259799787*-11121221111111-2-1-E34-45-12229922362233214363135434211777666677774454444555434166---444-G41B42222222222a4333498YBS2-46544439471A23565AJ-1-61UB99522222A9B78F944655733332233333-FC8BB9AB593-DBBCGFCHIE98349561234534-217777777777758636------------11-1-111-1--1----11521542223JJKHIFDCCC9FFHEFFEF3DJBH8B78-1757516213323B312741-33--3111115671122B4424333451121ACC56567A9A99EY5C-21-1-----11211111111-232775433-M8-D21A2223232225-4224-23---A334------8A564A47BB7877797-8879967A88879AA7AA48A8471187977677777757574433366772-778788878888---212-12332382C26----1---------1111111----7K343387683777818662-2--1---1278D333338587CBBKLLLLCDB5444--1244221111111111214--------1-31----2---21---16332323385lF4 4434UWX1J9A6JJPxjzn***i***qQQUUUUPOONQOQRONTSR*oryrw****wnhihgNJQLHI9JIKLIJIH9IHGMMLKLJGGbzfjfskPQTLKmObWh2RXU*xtpy*xbeXWWbY*te*b**m3*f*YWWaicXqbPZZYSiaPwVmbh*Wv*XjuaWuae*VZnM8EI9*878NQ****t**HGQNLIR ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.102 alpha/alpha toroid
[  99] 111---1111111111--------4---2-31-------------------1--111---11--1--- 1-911--2------1------2---5------3333-211-2122-1--------1----1----211------------212------------------2--1---------------------5--------1AA11---3211----31-222-2------2A93*------------422-1---21-555557451434543-211--44552-4-24111111B31--------------1-----1-------1----------------111------------------------------------------1---3535555343----2222133--1-3---1-----1--213-1--1-4211------1-576--121211------------22422124--2-1--111-131112-2--1-332332-1--------1---1-----------------------------------2--1111--11-1--------12-------132-3--2---23---4-1-1-34--2-1---------2-2---432----------1----------12-223--------------------------1------11--1--111111-----11---1--------1--------1-----------------------------------------------------------------------------------4------1-1-1-1------------------1--------1------22------1-------------1--22222--1-------------------1--------------------------------------------1--11111---1 ----116---2--1221121222111222223222222222221112233111111111111-------1--1-1------11111--11511-1-----1------7g1**********************R*********************************h********-2222----421421223--1-14 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.23 CUB-like
[ 100] 22222212111111121121212222222222222222222222222522442222222222222211 3333333333332333333-3333333333333333333333334333333333333333333333333333333333333333363344443422222222223333312222221222222454333335335222223332355334433333333333533333333333333333333333344333344444434433444433333343433332335555553432222222222222222222422222222222222222222222222222222422422444242424444444444444422222222234333555555555535335555645333553333333363333333444335333322222533353333333322222222222-3333333322323333333333333333353353553333333333333353353333333333322222222222222233333333333333333333335355335555563633733333333333333353533335333333333333335533323533353335333333333347755452253333333333333333333333343333343333335353333335333333333333322533332-33333333333332333233-3333333333333333333333333333333333333333333333333333333333333333333332222224445353533333333333333333333333335333333333333333333333333333233353333353533333333333333333334333333---1-11-125----2-353426232353327444433333533535332 QNOP*xf-*WT6cfXPRQSSSSSSSSTSSQURSSSRRSRPMSSRRRMPRSRQSPNRRRSSSSPPQIJJ9LLLOMPNNENNLMOOMNTSSLaMRPOQTSSRJNT***8feS**********************Q***twx**s***p**xp**h******t**w*tmk*invev*rKUVI*JLEJOfhp*SwVKJaockG ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.69 Left-handed superhelix
[ 101] 442123344333433433886672C89AA9783531111111-2312313887121111124224-45 6686UBABDDC979GFECC-CH55HJCCCCCDGHGHNILI7QOcGKEDADDAGGEDDC22PLGBTJOTUTH89AA9AA2238921222888918224--4D588I9I9A22222222222222877475445657BBBCD222I7C89789734553332336969BAB8132211132222MES88224889TSVQVRVXBUTWQUVBA7767VTV868HGJG9AA99AEL96666665666666586665857ADCA6668CD44DD553776CBC8999A98C88AAA9A9A99997667677776768FCDABBDDD938BAB888678777768446ADAD4543HAF1155234232224354156549HHHG333339AJNNB89GGFHFBBCCBCCCBCF-GGFFIHGJEFF3LJJHKKHIKJGEBD8DACCDBABBCCEBBBBBBBBBBB67BDA----------1232331333112211111199973A9899EJJJJGEBBBBHHFHEFEECDJGHBDBD88CCD8ADBBDEC9H98AC8766H86777777778E9A6875559448344448C77B87A9BABBFGA7722222222222233333332343444JIDBAC99D8G89AA879A999A8AA9A882-69989211222FHIFHHEGHHGGGGGGF-HGGHGHHGGHHGGGGGGGHHHIFIIGEHFGGHGGGGHGGGGGGJFEEGGGGA-EEEEEFEEEEEE22397645568688CICDAAAA8A577676669ABAABBB888CCHHHHGKFJEHFGFCEII5543454455ACCEEDFEDIFGGHDCDDDDDBCE777731A4565677--------31711111-----1-------1------47344232224898 3323MLI-NA97BBHDGHDEHGGMHLHAA8ACBBBA8A9BAAA899BCHLIFJLEHFEEHHGA88677587786877467788889999CMIGIGGABCCBAEMIQ2J*RlRWOQZPLIJIJSKlfCdL**g1XVfHLKKSKOROGOMGEPFCWLLMMRHHAJZNJEPFDKEGQHIRJG*JIHLMOORvGeKNPPKIEI ----------1111-----1---------------12--1----------------------------------------------------------------------------------------------------------------------------------2---- * d.113 Nudix
[ 102] 221144344334443327553543C66B778C56313643445AC68B6DGLH757453562322-11 ACE5BD99AAC77375566-6855AA66666989998CDG7ACCAA7C6D74CDA8B7225585A6BAA9644443652286654676IKII1K555117BB89CGL6B3333333333333347679B789FB6IJJIG343C3HEIIBCEA8BC75567NBBDIEHKB55455556545564743896486BBBBCCCD7EDBGGD6CBB87EDF7BB68A88888897E7666666666666655445675A16838262GC555667535586866633344544554444333432222322232226985647787684AH999B989A9A68AA78883683234B4697697475636585479B3A8776H*RG*9BMBC987AB9DBCABCF8E9BC91HFEGFXFM8R95tII9FEAIIGDL9C89899BCBFE9A8666666667887AG87331222331111444645436444433336F6954A7779dZr***cXNUMPH**ophcURsN*AG8B5799KCCAA7DC8DVA7AC897AB9BC89887546DBB89CBA4BE589BA97C6999ACC88889EAA79866I8788765A5555555B976A99ECAA8C99C89CBCEC97DAAAAAADC8FE2148669331333DC8CAD6EQQUFUSTQO-PEERSCSSGUQTFPPDPPPAACAABACOHNBLMNNNMNLNLBMENLMLALO649CI9FJHDEHII555967767BBBBDAE7CZ5UfRa556548**NFFOQFAL6M7BBCBFBHGDDBFFGFADFF9555575457FFFBEDDDDBCFCEdYRMUMMLLNceTh55F98877DB--------112----------------1-11-----4686565546589D M766A66-M76265DC9A58A997B98887878ABBB878797999B799DDADEG777DAA434-23154132333133-4441534576296527475486365-5U9Y59E5764455765A7476FdA-4653553655734635485263256*9GA9QM52343F67*58BBE*9999JIKJp9HEE9MDFHE ------1----------------1------------1----------------------------1-----------------------------------------------------------------2--------------------------------------1---- * b.81 Single-stranded left-handed beta-helix
[ 103] 88435686666666666777585AAAA52498324333222224445683333345464574848-33 9EB3QA9GCCG78669666-6F228L666668HCDEALPT5C7AB9764676FIJ9792266JFEHNHEJ54444555423492322299A93BDD---6E667H4H6N3333333333333325557555574598898111564554554335555555556445565353333353333EB88844195DGGGGGEEH9HEGEEGEECCAEEFF868DD98EEEEECJG788888888888888B766CC833DI43675BB55FF6A4766B89667BAAA79977777777777CCCCCCCCCAABC879554777E8DCET9989999G7F4D998CA87H371936B2II7LKLAB9A44885K424AB99523334DEM9B86DHNDDBBDAEADDADBI-DFHEFMGGBK43LDDGCDDOIHFH9E585DAHDFCFE87CCCCCCCCGCC9677K1111111111113334343311331111114BM449FFALIIIQKIJKKKIJJQPKKKKCIOKYNROK48IJCDA9BBEE7QAN68B36449866666663339AI5NW775985968782PIM6N8C9ABBBBB9CU311313323336366666662142144A6C9C3D7AGDEBAAA7AHDDEABACBAG72-34536221111KCOIHFAQLNVQUSUQQ-LROQQPTQRPLWQRSOTSLUQSFE9BAPLPLONPNNKOKOLLOKJKBLLLK71FCCCDC9CDDCD332422222355554B8FAAAEBD9AB87BEGBEGFCE8E884P5GGFGDKIHBDFFFHHII2222222223777JAAAAA978CFDDCEDEE8874444226E44557733333333634----3-1-5-331111154113---688555A5552756 6533DCD-UD9679B9EIHGIHFFIIHDDDDDDAA9DEEDDDDBCCDFDDGKIOHJDEEFFEDADABA8DBCBBDDC9CDACDDDDBB99GDECBJBBBBAJ9IGG2COFNHLCEOHEKIIFGEQFBJDP*I1FFXBAHGFFDPDBFHAADCBKFFBDJEMFELEFGKFMnEGJC8AA7*667EAHEPYGKCCFCBB7A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.124 NagB/RpiA/CoA transferase-like
[ 104] 22212236644443432222222336643465222332222224935335545323222236541123 6GR-u313234111PfbHH-Hw11bwHFHHGUxu**oc**3fAfEL281423HCB115--IEL-J9ORXM6-------2-51611222-1---22----2H39CU7C48---------------311111111211335211164L8CAA934533337632331GJHN83--2321-131272411-----244444746144467444553344821233321222218B2333323223333231122-2---11-1--135--11--1--1243-------31122222222222-------------433---333---124---1--11-1-822113-1----11-1-21-------1-----11F-4TGHE1111199TKN334B69J722331332336-ABA99ABF5VE1IFBDGEAJPHKG98GECEN99578F7J88888888844444741111111111131211111111111111117t*D4BHG6DRRUbUSJDFFEJJUFJJJJAJnOfEPLH34DDF8AD96EED8bG8A98779E3121111122398C351141233532222353564817FAFFGL451-2------11-------------244985948F48948ECCBI7AB89AB9GCBFK--23216------657D4676443644466-4677433646434646558BCCGA9946456555555676666933244441-433333333434---31211158775276A333635222224223JJJHG7923375NQOOCHJFDCEDHBBAB1111111113655A77687G8789EBBEHED6662222--3-661122--------1------1--------------------1--1-------B-4 4255kO71K86378HOPaWWVdScgXcLLGJIJDFCKNINIMMHFENMRkam**WRXLOLJLC9B8885965BBA66476ABBB9B69BKRDPdMGABA9B9ACEF2GkF*ulcbsnaeoVcnZ**f*i***1***Vnid*ag*kSjmeewbT*ScXWr9B6LGTaEYEfHPbKADXOH*CGBNLmgx*Q*YH9TRVXH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.17 Cystatin-like
[ 105] 44223422222222224122111322222222324222222222222233333433333333432234 1121211111121122222-22222122222221221222222211112121211111112212112111211111112222222222222222221122222222212111111111111112222222222222222222223111111111111111111111111111111111111133322221222222222222222222222222222222222222222222222222222222222222222121111111111111111211-2222222222222222222222212222222222222222333222225222222222222222222222222222222222223222222222222222222211111112222221222211111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111422322222222222222222232111111222222222222222222222222-22211111111111111111111111111111111-1111111111111111111111111111-1111111111111111111111111111111--1---1111111111111111111111111111111211111111111111111111111111111111111211111111111111111111111111111111111122222112111111111111111111221111112222222222222221---1--1-----11---11122222222221212 HEDD65d1R545NOSPQONOOOOONOMSSSVKSSSRRRKPMPQLOPPQQQRRRRNSOORQQQQJLIII5JJNJFKGIBHIJJLLKLPOKOZKQPORPPPPPOPZTb6QrD**********z***********9*****zy*****z**yw*yr******k***qm*g*wu****j6KTm*ehgPLVk**O*XBVGOLNJ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.51 Eukaryotic type KH-domain (KH-domain type I)
[ 106] 11-111122222224253314233OKLN-B8M---51-466547E-2U-12131615-642--14--1 24I2G22-111-2131211-121133222221411113--5B59N-2-B11------1--3461N-6KE9611111---21-1-A856----11----------B-1H----------1----1--------12-35576---4GA6JGAB14322------4564CDLA------------436--11-7IAFFHFIIBJFGDEGHE8DFCIDCFE7B6iACF333533UP--1-------11--------1---32--112222211112-1-1-21-1----1---------------11---------211----11-CPKf*RRQRVTRQUeK1dcI--2ULV22RBDN5dfIPEAMEE635CB31-CD-PKKF-1--44Aly*53CVhRTk------------gbxbbJVy3811KLLnedJcggBAi-D-9161CCCB8J---------B983-*cv-----------1------------------2D633B976AMMNJMLsIGIHHGUdMMNNCLKSZGPIJ--KJQSHfLKW34P94HOL98BGhV-------7743PTNPGELBLYLymXWg4jjndRigINYXLZnK53UDAF-BCAB6D5A5545555FXDC-11jY1IPGPGCF-UeedcLQKbXYdOSKOceR--116DF------IThiALF8887876677-877A855768868778775222cd33BDBBADECDDBAADAAC845366671-E7889BA8A998---1-----1---21eFq1112----------12222222221AJSSQQYhdyVVTVcZopq---------NGjdilkklkQXWuqDERNUNPDHH1111--rmQQBBGF77685676U51-------12-1------1-------A-BFF96A671R-- 531-9D1-4-*211E456-5676647466444465435553554556543544423455444457111-43245534233-44455--14785A544545574GIx-412UTbVaYSJDCCHIKaUEYHs*P4QFhDFHFODGQEEIHDGOC8qIKDFU5847ES65L79S7DOB-131--11115--F614--41-4- ---------------------------------------------------------------------------------1-------------------1------------------------------------------------------------------------- * h.4 Antiparallel coiled-coil
[ 107] 33223243444444442233323134522333222121111113212A1AD57111113112222222 7382633333333345555-5511465555547555569B347H46544333575334--455333556423333343325521121255A513331--282336455411111111111111322349446B2A1333422482E871528112222322213A25B3J22323222222231111111434363665C445E72793833363546435835444353A3444444334455434343449223333242233DE45333342343532224432324243333234223353223333332244332232A33522233432416377223253444V4IN3E7839E3S23DI2213242463331111144E68733434333333333233C-47346645563377766746559D543336343533634222222224533283211111111111S111111111111141A62365313332A779BA56233366773533234884556123534554357A453549223632222222245493642A35B333544341344438M953343AE54221221111121111111112122245534C7453654497F64756766644C574--11363--1---455645445555567C4-463745A5LD465664565955332454534373452676645545666462-44443443443411T321222546624D462222221111122324357322222A3556446464F566C8A82122221212634C44464q445543455563435645119133222211111111314-11-2-112111111112111111127421212222323 8D24*Gb-*HPBLHeXCFDeABADBIDBBF89AAACGABABAAAAEb*ABABACAAD*PAJJVIG9781l97A99Is2EE8GGW9AA9M*GUCCTfH9BX8dUEQ*4Bb9TOaaLTKECFFEFFPYHfHg*J2NKW9HKFHHH*8CEFDE*HDXGGl*WH*aN**v*D8CeZK*GDGoB*BBCOE**q*BRG89****C ---1-121--1111--1--1---111---------211112-222--1211---11-2---2213231211111111------------11-----1-------1-------1-1------1----1-----------1----------1-1--------1-112---2-11111 * e.8 DNA/RNA polymerases
[ 108] 766655676558799846676777DABCB9CA87777766667998B977997A989BABB5455487 89ABB99A99A9A9BBAAA-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-BCBCBBBCBCBBBBBCBBCCDCCBAABBBBBBBBBBBABBBBBCBBBBBABB7BBBBBBBBBBBB77BBA9A99BBBBBBCBDBABBBBAABAAABBBBBBBBAAAAAEBBBBBCCBBBCCCCBBBBAAAAAAAAAAAAAAAAAAAAAAAABBBBBBBBBBBBBBBBA8CCBCBB8998978796755557-556556555566755555599A99999998A7B A736BB91WBC36776776566666566666666665666567566777777677776777778877766778887737778888877776777797778667BCA29Z9MAFCCC7A789AABIJ5B9VpG-DBGA888CA8A979896B76B8C88AFD9CCAG6CECABEBEHFFK*IKIHHPMbc6PMFFCAA9B -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.52 Alpha-lytic protease prodomain-like
[ 109] 88B8678899999988CA899899C999BA8886666688889756866599A478677676676-46 9AA5DA999999A9BAACC-ED55BCCCCCCADDDDDDDD8CDCDEA9BAE999AB9966DDCBBAEEDD9AAAAB9A99ABB75977B9AD49982229C99AB89C81------1331111366669656777DDDFEAA9DDCBBAEDC9A99898A79A88BECBC778777777889BBBDD99AAABCCCCDCEDCFDCDEDDBBBCBDCCA9BBBCBEDDDDDCGCBBBBBBBBBBBBB8BBBBBDECDDDEEEGEEEDDDDBDCEDBEEFCCCDDCDEBBDDDDDDDDDDDCDDDDDDDDEDDDDCDDECCCDDBCBDGGGGGGGGGHECCBBCFFFCDA8A99A98BBAC96AA99AAAB8B9978966D4444488B888668696778898788888277978977CB94A999CCA999AA656589AAADAAA9977777777A88776995444444444112143-513--33-334455967587789BBBABBC9AABDDBFBBBBADCBCDDFC77FFDC99D99BBF97888B78999989AAA9889B87B7D9D98A8B98895A89988989BBEBFC99788877777776666666667888A9998B8A696A999A9A999A999A9AA9A993-7B9784425549CB9A999BBA99AB99-A999AA99A9A999999998BA99BDB9999999999899999A9989999839BBBABBBBCBB336A667768AABA8FABAAAAAA9BBBB999AAAAAAAB999E7AABABA9A9E9D9EBBC76767767668AAA999998999998789888885666448A77667755565656865----5-545354544455754544596799898889C68 6622ECA-TBE5CBCDFEEECCFFEFGFECEEDDDBECBCCBCECDEEDDDAMCCDFFDEEECBCBDC9DEGCEBIGDFGCABBBBEDEBGBFBBCB9BAADBIHL-CO8PQaQMPHDDGBEGBJMHNC**K-KIYFEHDMDEPFCEFGEFDASCHKGE9ELCHACCPAECCFFAAECB*CABCAPLkTFWID9PHHKD -------1---------------1--------------------------------------------------------------------------------------------------------------------------------------------4---------- * c.61 PRTase-like
[ 110] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------s*****V*********T***************oq****dd2BL---------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.212 KRAB domain (Kruppel-associated box)
[ 111] 1-----------------111--22--1-1-413---4----3-4--2148-1-111-3--------- 1132Z15111-1112112--13--5122212531111A12J112--11C212---111--786-V32FH6I----1116814-111--111---------1--11-221--------------------------42212---G1122122111111112651311211211111115111111211-----1LEWLWcUe6ioaXQnFE9981dg7---5--6IJHIIG6H2EEGCGF9DEEEEFE24242F16-65--12-772212313--58622224525922-----------------24322-2D1----1-1-G--9-11111114-2M3--2653E2r45-24--125---1------A---2-1111111111112331111111211111111112-22122222311-3112121111113111131211111111111111111111111----------111111111111111-----1121-E8658L55559745563331BBBB88556355B1167521411B21221232121141111111111-11116-3-----------12212131-----1C-2-111-111111----------------56-11L315113233331226443322423----111------bN--5RcYhhjYfgYXV-fVQhaOMfdZgUeVYYYYLRQO47HOraFRTTTVSYYYQSRTXZCFDMFPO--HGGGHHFDGHHH---1---------73A------1-3---3---155525-6-121TCDBC265F1446517661--------12224222226422263222222327545111-22------------------------1----------------1--1-------1- B843*oE-F565A9A77B5686657667787777776656B56896A87999BH98778777IDB88A2IA6D8CA85ACAEJLIQ5555A676776677677LIJ3ME7**********z***********8***s********v**yo*zs******Xm**ntYc*cjtRpeP5596*66875KGQO7EA8AB6666 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * b.2 Common fold of diphtheria toxin/transcription factors/cytochrome f
[ 112] 33424535444343555233222556843455333443433336475816999634345462234134 6K85823344432265522-262244222223599A3574687663244232334422225543538773642223338698C6585587884666G-15B698E68D7-------11111114454565555E5CCCFE756FB677B665897744444479475596444444554444IDED8FG4DF9DDDDDDBFDDEEEFEAEBB9AEDD798GBDGABBAAAGI97777777777777788888B7A699797769A8899879AA586777767768776667776767667556677677678885557776ERELYGHGFGHHDJEE5NNBBBBJBK35CKJOLcZIORVDPQIFFEKC54JEF64342444443B9C5658677844444444446-HFEFIADD48615668785AB8566555444776556883333333345653O57---1111111Oj538846C531563111123464479878AAABABC878788DE999968CC96E6A25997KGEBCG45P78FCVE9FAOB3333333676AOjBcYINKbYFmgYYY9USUbQOVKUBCBBDCLME6555666674554444444C897433SNCNMIGBPDBJPJKMKIFPLLFIMGFGVR--46CDM------89BB6897777776777-8767877778887677668A999979A7777888787787777967567768-856677767777--4733333568666T6K43445433233444555565565659GGGFGBIFDKEDEADCDE444335434GDBCHPNPQLGHOVU98CABBBA99544411UADCABBB33333333G6735445-1141144111154411444JPAKOHJKKL3H56 562388A-O8B5DCC4665655578755534546547787677555344655895444455543433324332243533334444311159565476673443E9B27LBcdqhYZWTPQQRRQ*uO*U***-*Z*LSTVgUReTJRSPORONpVSTPVFMNMLKFJbFER8ONH9dNBy999AAIBAI5HBIMLHIIJ ---------------------1-------------11-1------------11-11----------------------------------------------------------1-------------------------------------------------------2---- * a.211 HD-domain/PDEase-like
[ 113] 433256BGLEEIGNHA538B8657645655863262356677476467578C72AC59JGG7655-33 8DA4Z67B668585x****-*VPP*V******VWVciIQT8FHE8F6459A399958533GDE4fRa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c8F5553455554545333333335668887677886746566556554755655557572-2752A11-1118B674B4BCC9B99ACB-CCBB987B9FC9A99B99AGFD55656CCBBCCCCCCCDCCBC97678887426556555665552227333335555999786665554455325557889867788I6B9ABBEBADBECCD9AB455555455834445555556366C9CDBDD9984444115C7655772222212132211111---12-312221121221118668898999396C 2422754-A45-33843444534432344444422243233334444333444634344333223224223322233234233323223875388874557448552369WFD8AK897A97I7Mb6ZAM*C1CEK8978L85XF6E5B8F*5G7777GDAA7B8D6E8JF57M45BA8*987EEJDKO4LL54A5664 ---1-1-1-----------1-1-11----------111-1----------------------------------------------------1---------------------------------1---------------------------------1---2-----1111- * a.25 Ferritin-like
[ 114] 33344253444454453433333364465445524456665555647833454233333333333211 4433554655544564455-56335655555555655655345454444342675633224433557667332223222264233522112221111--15252572333333333333333333333333342442252111464444352323355553343333363231223331323222222212-45555544435654662311254441314--1222222541322323243333333222221111112111221211111111443222111111111111111111111111111211112222222213566455555654742133333322523412453363464544331542-44255543333466D989786868766666666667-CB9AD9BB874365555665668555767758656696855555555333347632222222222222222222222222222243345267666778787677767789777767788666656767796556666787653635542232332334455364644455556561636654725334465634444365555465444444425543435545433442454554474545555535462-2374422122243335433887364443-94474465767764443434443344434333334333343343463444432444444444444222222222555535755434333344433333445445455342585536754444556A8322222222554442222263333445555555633331154556677--------2211111-------1------1---111-22--1211124-1 BBCFaUN2*fh7JMWUTZXOOPMMQJOKKGLJLNKIOMKLKLLHFGTQNPTOSROQZbTTQSFCFCDD6ADDDDDEDACDDDDDBDFFF*dPTVchKIOMHXIVWW3Y*I*svyz*tjdgagmj**b*a***D*v*Yjiaqgn*eSmZZV*aR*e*thjTgfcgYeRpnieTkhJB*w**jlidkxfi*Xw*u***t*m ----------------1--1-1--------------1----------------------------------------1----111---1--------------------1-11---1---1-1---1-------111--------11-------------1--1------2211- * b.85 beta-clip
[ 115] 11---1-----------21-----1--1----------------2212--311-1-1----2------ CNa6bDACCCCCACMJKMM-MQAAQVMMMMMIRQQRQVYT8GAEHGFD6FC9FEC57G44HK88PDRdcSA75765556598A34344CB9A39555--9IADQMDN9M44444444444444465556655676899FG---BDJGGLDDD8988688877CD98GILH567555565565DBA56535CALfflflliqUofjkmiNHOOKLknoDCCHK9AB9999AfPA8A9A87667AA86979BA6BCD9EF99FCCECBBGFA7D77D888BBBBAAAAAA88888888888ABBBBBBBBCB9BM88DC9777A6EBHDAAABFECGCCFDEE9EEEGAB97LAC77EEDCAA7F78AAC7375S64ULLN46666BFRQPBB8GGGGGCCCFCACABCH-FFHFGIEGEIE5IJJGFGFIIIIKCCDMRADDB9AC9BF666666668898898B33111111--33677758865577632324FDGK9ABB9DLNOOQMIIIIGLLKFLLLLALTJEFHIH55GFD99B99H9ADK7BA88767C7555555557778BE9A8935478744539999779679A8AKK7C6443544343534333333344335BBDD7ABABAG98BDDDCDACCCCCDCAEDDA2-6374812-222IEA9EFDGGGGGFGFGF-FGIGHFEGFGFFHEFGFFFJIG9BHGAFFFEFGFFGFECFCEGICDDECDF64HBCCCDBCCCCC335F67656FIGD89E88867767487746547FDGEFBB7C8BAIHJHEGDIDEDEEDHFH66757776678B9FAAAAABB9D8KIB9A9A99787773256DDAA9944444444642----2---1--------2-------44533343335BAA 2111BA5-521-1229BD876A8KAHD6634449877556666445649IIJcL989C5646414----1--1-2------11111---382B332---2--31---5XDe587893543345394267FW51535352345454444333325444456539JA318-11EG9422116222-5A1-D71311C1227 --------------1--------------------------------------------------------------------------1-1-111------1------------------------------------------------------------------------ * e.3 beta-lactamase/transpeptidase-like
[ 116] 33----9566669A67-35-3--2QDEJ48NC------111-165-4--1856--------211--Jb 8IC29778888474A6944-491192444444C2A5BQJN455713544111E3F141119AE456797941111111----55-614------------A1C642952--------------11----1-----ADD55---AD3BE6DD334443436958317BA6B32222224322365-52---G356666666326396626755556566AE9624111111DB21113111111111114131-2312214222332222-22222-3--------2--12222222222-------------------------1-33332------1-11----1----6----11--2------------9-5955H111118FJHRKCN89768AAAAA9A9AAG1DGFALKDBNE91A99DKFTF9CLLBb488I28585965K5555555576645632111111111122222222222222111111A7AB-2998EGCCCCG7EDDDGG8DJJJJ9GDHF7B9J11HNJP96F9CF93A3IB38955974544424NSH7655--4-351-3-447-8765C851-ECLBEV-3-114-333333---------31-4B44525C69596945455599185449316819111G4-71111118B8A4888888888B88-8B8888888B888888888B8B4477877777777777777778876777841888888888888111B141114877BA715666635333333395744771433388BBBBGEG9GHJHJEA7D311111111D21192111174666A777777777777744--775555----------------------------------------------9E-3 21--2-C-622-BCGePeSMKOGZhSTFGFHJIMKN8CABCABHFGiWTXhfkxKQvRJXTW899999499-85678388CCFF99234RVyP*NpEFED6YGJHF-1x6*srf*s*bbcTVgf**cec**q7nf*cddcpeipvZheaakYN*f*gfRdl*4MkAFQJL*57D-1ZM5Y323QI****h**22IISXF -----------------------51------------------------------------------------------------------------------------------------------------------------------------------------------ * b.6 Cupredoxin-like
[ 117] 33----3242242442-122---2A55B85991-1--------26231-2435-11111112-1--36 AXe3t538EEF332WWLCC-Cf22VcCBCCCKhbhdqj**2YEcNmBL4EH4XVW7BO--UbY3PJjqzj82---6312-31I--1--545315223--2H3BAX8N7J11111111111111122253323333899C9---LEX8ACBB88788236766874KCFSE213122211132CEC67111A4FWUYUYYYbEUYUXYUKLECEHUUd767MKHLHJJJGFaW8FFDFCEDEEEEFEEGAAFMJ-3-67-3---1144461323238CF8887333544465565565555455555555535999445788B1C4AA333776626469221222F1221C151-A9411-222-2232132N-7SHIO----2CEoUVC7AJ7FFDFHFHFEGEFGO-BEIEBVENSjO-rUUPedesseXeNKKIF7RMG9FFAEP444444445EE645E5----------------------------12DV*L39MJFMWabaVZNGHIESScTMMMM8JnRkUZVP12KMHJIEEEQMT7aG9D95738O3-21222253C5K9B5431222163322-767475944CDHENV452-1--1---1--2--------1--167HG3D58M7PE8FHEGEFECFEECBGCECHJ--17428------47C85844444444444-4446444434444444444IIG996846465546565556556J44344433-433333333333--1F121126B8955K8H3333242231222246666649143D6LLJLEFDHEEAHAF8A8211-111112788HHDEEDHHEFIPODIGIICBE22221151AA66AA--------3-5-------------------------11211-1---3J28 43--98A-92--25BAAE8CEDACEBGA99A89AA7CGDEEED988456IAHJM89899666346232223144443334255543232131A3241121113324-4Y8GAAE977647666676275BY6-66B5656656987665765574686E9C729875555455968A86T555ECTFJb6KDCBB642B ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.32 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
[ 118] ----------------11-----21112122236356333333111251111132424433---2211 --------------------------------------31-1--------------1----------211------------12-1--------------------------------------------------------------------------------1-1----------------11------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- C9CCUVI5*ToFLLVZLMHNNOOPNOMWdKNHKKONJPLONNNaONONNPPQPQINQNPNNOPNROONGOSOPMSOPJPONRSSOSRROUeTLWZtLLLMVbMUcZFX*X****************w*****-******q*x***y********t****YMj****K*u*ns**ON**T*ONPhi**v*n*fMYVTUOt -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------2- * a.22 Histone-fold
[ 119] 22---------------322122------------------------------------------2-- 6AU-61------1-22222-22222222222-22222222266622342222322222--BD23666666611111114544244444ADEA2A774--9G4KCCAI8Q888888888988885666666666I6666AA22266EAA8AAA4488444444AA8CEEIC4444444444449DD5522-67777777777777777777777A7777777777555555667555555555555555555555545555544555555435555555555577565655555555555555555555555555555555556EBE7BBBBBBC8B7A7FFC9997A645A552222222246226676223O68AEEA2222266B6A6666666644462266246-86A6666666626222256565226664C666666666666666666266626A66666666666--22222222222226666-FA6AA44444------------------------888844444256446444444484444441111111444444A988588C8A9BB88A8A8888CAPPESUK8E588585555545555555555555522DD5G88HC8G5KKKKKDDEKKKHGEGKHGH--18444------896A778BBBBBBBBBB-BBBBBB7BBBBBBBBBBBB999BB66A77677777777777777BB7A77B5-B77777777777---C44444444444C5C777541544455554888888C888AE888889886CCCC788844444444498CCGDDDDDCDFCC444444444444444-A266666689988989444-------------------------22262222224G8C IHe*NNE-sIGAIIJIIJIEJIIIMIIJIIIHIIIIIIJIIIIILLHIIIIIIqIJIMJIIIMOONNNNMMNOKOMNFJNNMMMNVIHIIVEIEFFEEEEMEESUS4R*VafgOWUYJJLKKOFcdMkKx*O5UTWEMQNLJKSHGKQLFKKKbIXPLMIadLNLMQWQZpKnTINKVL*QMMOQlXhYJiUTZNQPMP --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * d.185 LuxS/MPP-like metallohydrolase
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gIPEUHLKPHFHDEJHQMGLDq*M2RRkEHEpOGHIG8IEEDHBGRGIFHKFHQEFFJAIEGSAFJFDDHF*GEEGDIISUCLJEGHDCBJ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.51 Anticodon-binding domain-like
[ 121] 65-1--ABBBDBBCAA-253643H96661-7C-----------------------------5771-11 4567i4-6443947p**dd-d*44**dddddv********4*G*45552682BBCB9C--UWk1RMdbQeK--------384D-----11111133---1545664565--------------------------787BB---DA43-3224--12----1-1-112251------------ABB8A--1G756666648677667665666666768FDCC11------6413333332333333221113--1---1----22--------------------111------------------------1--111---111316444444444424332221-6-316-13-C915B9-19---11-3171-VLLb1111194kTf787WHXXNAA9A9AA797A-CCGCCLBLFCf1PFFMBA9ECEACGQAWCADF9788D9J63666666C11129C6-----------------------------1PXnS19YMEXKPSbfNKIOOIIIWKSSSSEQmKul**v46KLFF8LJJbKOOal36B-1-3862222222212J994sKQ-----1-----765-C-5--88A8HJ78---11-------1--------1-----54-AG5A8HE1676667AH6666B6H8699--1231-------42841214445455445-454544453444555455546511682665356655464644633435234--233343323343---6222228888-ME45--------1-11--1QRRPRHR8CAM3baadJYMSOPPOLIGEG1111111112111422222462458787677566------12CCBADD----------1-------------------------1--11-1----1-4 ----GFB-D64-BBEHGIGIDEGHDFMHHADDDAAAFEEECEEHGGCB8ABEHQCC8A8999B34221131141311111144454---ANBGBA98777DBELIM-GFDaJZFEINFDFEFHETIDQDn*J-MIZFGEELCEME8EGCEHD7NFGEEWIQTASGKHHCGHLWJR3677u655A8C9BPE8976TKMHF ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.6 Acyl-CoA dehydrogenase NM domain-like
[ 122] 6693B3333333333366333333C99C99CC6696666666669696369966888ABBB3333-66 99C99CCCCCCCC9C6CCC-IC99CCCCCCCCCCCCCCCC9FFFC9F9CCCCCCFCC999CCCC999FFF966666669666973355666666663--666666666666666666666666666666C666CCCBBED666C3FFCC9CC66CC999999CCC9CCCC999699999699696BB99C6767777777777777796666667779C93666CCCCCCA6766666666666666666666666666666666666666666333399999996666666666666699999999999996996669996A839C9999999999ACEEC66699C669669C66CFD9A66977BA66699669996666669C996669999CCCCCCCC9CC9-99999AC96C66999999C9999966666999C999966999999996CC6696933----------333333333333333-366C9666999666666666666666666666669C6696666669666669699666969C9656666666699669699699999999996FCICCCFIC9999CC99966666666666666666666669C9996FC9C96969CCECC9C99FC999999993-69669-3-33399996C69CCC99C999-C99C9C9CC9C9CCC9CCC7C999666C9CCCDCCCCCCCCCC99969A69969CCCCCCCCC9C66666666666669996699966966963699699999996996C666699996C99C9999999999999C9CCCFFFFFFCFCF99999999999999669666666655545444549----3-4-33333---63331-33399999696666636 6579969-M937AA7AAAB9DCDCACAAAAA8AAAAAAAA79A9A96777777747767777AAA99A9BCCAAACC9CC8AAA8ADCDAH9AA9A7777AF9A9F79E9IRIJIJJDCEDFFDSSDTCV*G-SCQDIFCLBFJFEFBCFEDCOFPGGJAOrAH9CBG8AQECEAHBB8*A99CGIGQVAMCGEEA98A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.84 Phosphoglucomutase, first 3 domains
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cuaXebKLLIOSOmaLhO**V1cVlBNMOfORQPIROHGRHGVQTSRTIKVFGGFEECJLDIHEKTQZ*WWROLZhvz7ZbUVNMHI* ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.26 FKBP-like
[ 124] ------------------------11111121------------------------------------ -----111111--1111----1--11-----111111111-1--111-111-11111---111-1122111-----------3--------------------------------------------------------------G8787721144556645451AA9F6444434344544-------------------------------------1-------------------------------------1---------------1----2222---1111111111111111111111111112221112221---------------------------1-------------------------SJKN11111ECUXa89BGDEID7788778888C-HHHHFMLNBNT1KDDEKJLRRKLNFHEJEAEIA6BADFL545555557B9467B711-11111--11111111111111111111DIQG4BDDATKLNONKDCCDCGGUKEEEFAEQGOFKNE27EFIBGGBCJHOBT84A93333F422222224559A34-----------------------4444CQ---------------------------66A85A9AH6E78B99998A98886A79B59E--24433------BCAB5A7ABB9AAAAAA-BAAAA99A8AB9AAAAAABCEDDD454B8ABABBBBBBBBBBADAA999992-745455555555--1622222555546F7A444626122222114CCDCD7B8AAB1JKKJFJHKAFDFFBCCC2222222223688B7777798A89DDFCECC8892222222-441233-----------------------------------------------1-- 2355RWK-N952BCDQSQLMRWQWWRQGHCGDFKMLFFCEEFF99ANKSkUZgWEHGHECBDD694764C59798AA58A7EEEBA9BARlKSSNL9AB7EBGMJM-G*X*khWboeUSMSfcW**O*U**t-zc*TSOOqPRmaPUORMgQHnTVReUm*dMnkbP*nlWx*c*CNLL*FFEKPk***H**JLjbVhh ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.45 GST C-terminal domain-like
[ 125] 11-1--------------3-3--12------2-----------------15------1---------- IN*2222222222222222-222222222222222222222222222222222222222222322222222------------9AOGL5551-7---442GEAIYN*6J--------------3GCCCCAA9FABA77C9---66D6A555355AA4447544559878514222124-2216CAGG----444444444444444444455444444755444------734---------------------------------------------------------------------------------------------------------------------7--3-23------1--------J3*NDEJ12112LW*ymcKMRLPSRAAAAAAA9AAJ2PjWLadTbLN8-IEFCTLKTPLVYUZAE8sERRWRRUImRRRRRRRRPRSMATDA2222223222222222222222222222236QWBBKVRKar**x*qdRVVQyvvqknnjVj*oyhrk*FajdeufPZVikdahJcQViGPIOJCC977A7RXaZftG-3524764237772LIRCLMG61KOOOd*-6VGJHBIFIIAF9A7999999TK6XfCDHF-DQMVALKJENLONIMJIIIGHLMXGKT---XMBc------34--4-422222222-2-222222222222222222-333-----2222222222222222Y22-2222--944444344444---G-----CCCCbEU-85555441-1113114-------NNIOInnpnZfmeLgegaa989---------GDEESCCCCCNQKGGFD99GA9CCA1111DDZ-LLEGGH----------------------------------------------IO87 33--223-93212222222222222222222222222222222222222222222222222222222222232223333322222222224222222222222325-2I295655422254122683B49Z31886143633274322325243-314621433222434933534424k2334497AM25554B2326 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.3 Cytochrome c
[ 126] 11361388888888881766776475567567555557555554445445545437324-36441-78 7897I978888A88CBBAA-AC66BDAAAAA9CCCCACHH7D9B88778AA7B8A99877AAB7BCE9B9A78887775587B8989899A94844322677997777722222222222222366577755597AAACB545AA9779777778888888898788887888888888888778775557AB88989A998999999AAAAAB999AAA9A9A777777DA888888888888888988889756888C595DC998878A895777666656666666666676666666666666666666766666667B5674446665646899965657564375576AA698656655547245766EBBC77777ABGBC997CBDBCBBBBBBBBBBB-99999B98ACC7FDDEEEEEDFBBAAA9BAAEAAAAABC98999999A88889BB776666666611222222222222277777ABA96ADBBBAAABBABAAAAAAABBBBB8ACBCDGFD78AA9A9B9AEBCCDF88A999AB87777777888BAC695957A867877758888C7987EEBEEE8886576666666565555555686658899A8B888989AB99A8AA99A9BA9999A725579A4423339AAC9999998999999-99999999999998999989A9AA9999998999999999989A99999998898888888888844797777799998BC98555757644446557CCCCCA9989A9EEEEAECEEBACCBEDD888788888A88898888889899AABAAAAAAA7777777599AA9911111111421-------------------------32433555566866 331177A-D54-99BAACBCBBADCECBBBBBB999AA9AA89BCBA99CBBEB8CA9AAA9B9999987A8A99CB3BB989998888AEAAA9D9AA9A97GHD-BG8KEIHLLIDCACCDCRKBOAp*N-MGK9DBBD9DH9ADB8DKDAGCGDBHAMSBHA77Q99cLCN79789*878BBH6HKAEICDFCABE ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.30 PreATP-grasp domain
[ 127] 22111132443542262------2IDE955IA4313223D69524113-3D32-11323213261-37 97U2B496654355ABB44-4E2297656764aAKFKEYY2GMZ4423533AD3E27222AKT2F6GGFA63444FIE5468521211aPwZ2bA43--4M3F985DB442442222442222C232455442633335326AB5RFEF4711146G3H31455-4DEP11411221B2143C9644234653BFEFHFHG9EMH8CD4797367BEB7DO465B23366639DG7A55976BBD7659C75E8666A586579A98775C55429BEB88746345663477D8687B579B869A655565ED664A7968D67EB767A99BF8BFDB43437472426JC7F7OGHB2B54353933464JQ4584C42H59KCUOFC7A2898887888588O-SIMJHQHFIf94A88Q93UQ68EH7N666NCFEFDA8DBIIIIIIIIM89A5S372222222222Ha223322332222222221EGBB36A44QDDHGDBR6777RPZfHCBBCHEbO9Bjb29SLJHJBL7KNPCE9C9CF5485C56234236CBi9G4DP97689BkBAB5692CG7767I86966D7A5B525141162323321222A3446EC4EBFY5B7BAF5KNWOADGOBII7JAAJ8A--59856------HBHD8IABUWMCLHQHB1UC9IHKOAJHUGGCB8CAAGRDQHQSBEF59BE6CGABIBF9GHFD6JLJ9E-FCBA8ED9CF8F--4335435897D55846633482363356A86967ADD36BBB44BPB6C8GALMFGJUOC322225222DC96IAB7IAIC7CEE5NCODH989DBBA--435534442863--1-523-----121-12-------2-1-33211122121112M96 2211J11-P12-11111111121111233231211121111112111211111111271111111111112111111-11111111111831173T31161e125n-24F74544841111132331223O2-4222222111B21111122142442812424P91312A22F218g3J33322211J12932G*9F7 11-------1-----1111-1-2---1--111111-----1-1111----1111--1-2-1----------------1----1111111--1111-1111111--211111111--111-1-1--221--1-1--1111111-111-1--1-1-1111----1--11---1---- * d.163 DNA breaking-rejoining enzymes
[ 128] 663395B5BDDECEGNOBMQA77E411368531151B224252963IL32I6C6A78DC5A2226321 59F5C86688866786677-7844797777766666978B6AED6A67665666545522A7B49788B8786668772265679BEA53972B4331-2433454E93222222222222222348559247345KIZf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fEJ855A67A98988D9BBDA89BAABABA8A99999A9788B9CB88E9A989434444246534355555433334AAA4FD7B9E8698757DAC3AlC*GNHNLLNONHLMGyjKgO**b3dWoRMNLZLMROIQKODVHIoNQFHJCABOFFB7H8BDGMGA8PFI*GECEEMRLU9ZMGFILKKO ------------------------------------1-------------------------1-----------------------------------------------------------------------------------------------------------1---- * d.218 Nucleotidyltransferase
[ 129] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------D--------------------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-223----------------------------------------------1-----------------------------1-1--------------------------------------------------------------------- 1--1hdI-849-OM*mYjRWXXXafbfTVRTWVXVUQaVaQZXPSRMSXedUxVJSYWUTUWqEDBEC3C9BD8A8868B9CFFAFABA**kY***GDIHNEK**c1Y***y*x**ohXacj*m**W*k***6***QcXV*dq*uTweiYvdR*dznu*RXQTuq*FbQddF**d4WVWj7BApB****a**DEFMOLB --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * a.158 F-box domain
[ 130] 32-7243--------7-1543127847Q2KEE422-212333233274A8yvC-333F8336214-K1 CV*1V211---21-43355-57225855555586866AB847364D81-642A23118--7A5-D2FILL6111111111-15-44-5LIMG-M66---6Q7CDZHOII-------------131--11---15-EEEHI222J5B555456-344625442542F78B711--11111-217493397-4-45555545514746763122344462323113111111871111111111111111111112112212222111122111211111-------1-111111111111-------------122---22213-2422323224221325521115231-A112585A6421313654211-Q2*989F-----6D8C94-2111331-111111-11-9777866A654-344443436254-354A829344461777777777777A69A211111111--2222222222212211121496J632222665455853333446B456624568889811565ED4769451B9329776A51-1-222-4525786628-231243111-343354B1-ABCBZh-3-2------------------2-14599622865KBBE3FCBCBFDDCDC9GDGHAHQ1-15254------55332A43335354453-3435344423343443444576476535424444445545445755222261-322222222422--1G-----333342B34---1-1---------44554343127798A8786568877B755211111111223231111162225DFIGJGFDDD7757--226622331112112131--1--------------1--------68423664552Q15 9841KER-gGGAOIRFFGJNLFGLRROIGFEHHDDDFFGECIGFJECHLYLIVUMIJNEDDFB99A8C5AC6CAAA83997A99BACDEDOIFKNfHECAEAHFGH1KhP*hnXafdNLWRbdX*yKzR**v6*g*SQRIqTcrSMeRMH*OKxUiZbePngMeXLLXKOzKfTf8dSL*IIFLLiUZYMKWFBOUPXX -----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------4---- * b.70 8-bladed beta-propeller
[ 131] 34334332322222333244444444444444444555666664444444444444444444444322 5564466666675655556-75445555555555556766455544655444555555334445545555445556555444464866777747-64225779699A49-5655555-545558444444444445555544464667677755667777767656666547444447444477766662877-AAAAAAA9AAAAAA667777AAA77787777777779A87777777777777777777-7778877777887788888776888888888887788888888888888888888888889A8888888899798888888989887799AA998776995466484464766668378657888855555676666666666655555555556288777777566466656666666666AA6776666677766666666666668864444444455335555555556555323436767566667888988888888888888878888888878777A8CACCBAAA8BB99988CB89A99996768BAD486A7B66676665878688978DDDCIC6797777777777676666666A778988DDBBCCG9EFCFIIIIJKKFFFHI1KJHJK4176778555555BAAAACCBBBBBBBBBB-BBBBBBBBBBBBBBBBBBBCCCAAAACBBBBBBBBBBBBBBBBDBBBABBB73CAAABAAAABBB446A5555577779AB9CBBBABB9BBAA9A9BAAA9AAAABABDBBBBBBBBB2BBBBBBB555555555CFEEEDDDDDDDFDDEEDDDDDCDC666655888867765556555596744445-545444344444434544466566555555976 FE66FFB-*MM8AAA5677666666566666676656666666666666666566656666678888857AA788BA89A8888787887C767976666486C9C5A*LOCHDDIGFECAEDBPLCHCb*H1GFH9EBAHEDEFBEGEBF89EDCGDF7EFBIAHBGA9J99B9ELPV*RPQIGIKIR7NNWeOJKLP ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.265 Pseudouridine synthase
[ 132] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-1--------------------------------------------------------------------------------------------------------------------------------------------------- DB89YZc-*gV-aZnafgbcddcifigZZYZbZcbXbZaYYYZYaZabbdhgoiaddaYbbadWaSUXPYVWXZZbZUZZYYXYXYQOOa*bfbbfbccYcaczr*-h*t*******pjyonpt**k*k***2*x*hzkk*mp*hequqfreV*qrqooXklXhbYc*ak*djuYVjeh*heeYf*z**f*z*vqolk* --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * f.42 Mitochondrial carrier
[ 133] 221---5366666665145331117EA788C8--311111111-4-52E1745--------322--68 56B9779DEEE795988CC-CE558GCCCCC5IIJKBHPO487A95878973KDF7A822DB8197D9AC8----1-1--14F646682222-1661--186AAB5A8411111111111111332374722542DDDDD111BAB9A966636783333336446ABA6333333333333D88CB---BD7BBCBCC9C5EACCBA559965CDB9D8C9ED433333B9588846966877867457345222112122233113222222-5463335111422244444455552222222222222344222444629523CCCCCAA4A31811177761-3432431BB539-1-2---12-22A79955411111C7GKS7576668733333333334-66758685F65-8663566555886D77698A8D8968955555555C3344744111111111111221122222222111117646347ML8DGFGGGFEBBB9FFIICDDB6AIKXLFEI6CGGAB89A9NEODMEAD9F4655622222223325BG8AJ5H7GD38E7782B8BB8IG647687997D6232-2233241111111115999B67B9A8698688A8ACCA7CABBB9CABA9GB3-16D8D221222B897EC7CCDCCCACCC-DCCCCCCCCCDCCCCCCCCFGG7776698999999999999998CB9677C52788878888877222754555444499D7B47754A5323333346666656242KFEEAE9HAGHAIA9GIEE666456546D789D99999CB7777777877778433443D7BB4455111111114-411111--12--------1-----------------7629 43--BAD-SDB69BC99A9BCBBACA98987578988A67778A9A88BBBBEI88A69A9AA89AA977AC898AB8AD987877888BCA9A987788799CGG18ZFZORQQKWHJKHMOLaWEoJ**Z2dPvDGIGUGKTIGMJEAQBEYIOIMSFKGFliA6A9B9JNO88RHQ*MMJQJXNTR9PIKHNJHHC ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.46 Rhodanese/Cell cycle control phosphatase
[ 134] ------1111111111-1-----11----11-112---111112-111-1331----1121111---- -221932533342232222-26--23222221543445542567997467556653345576C254B8BE44333333222-1---11CB982C33---383767496D---------------32133312153-1112111416555453222211111132144441111111111111434----11-15555554636555542-11-1575---2323222221321111--11111111-211--4311221221211222211111122222233343223333443333333333333333333432223332-2112332333333322---33331111--2--1122-111----1-1256-B755743333343433224437355455554445-6755654378347776BB7B9A8742354764646665544444444344533551121111111342222222222222111114374334444777677455556667666645665767633554545555454734445634532222222334573735521221121121313--2-324464FB33322422222121211111112-113336726567476664444555454554444661-26333------44453323333333433-33333333333333333333333323335343433333434434233333321222222222222113222222333333B431112322111131124433433444427787567656665655522222222226669333339968998AAAAA676333311211144771111111132-------12-111-111---12-222---11------747 9C55uGN-aFE489HABGFMDDBFCKECCDBADAAABCCCCBBB7C7kBDFGKHDDF*EEEEJAD9995FBBD9BFB7BC9EDJCD888HPLBEFJCCBAANDJ**3M*q**rgj*WNQRPRPP**W*Q**d5fZjLNQSXSU*SFSQOJ*JMxRWTZ*MfS*****OBDKGK*L9Z*I*HGFIEfja*7ndBMWYZfO --------------------------------------------------------------------------------------------------------------------------------------------------------------------------4---- * d.151 DNase I-like
[ 135] 331354434333333325141313F88AFD83332123333331222343A86163222423221115 28q26112222---46477-8511D766666786661B9A13364MA11112519213--4462345479343334432121E1----SRdK2R771--8I56EM3a6P---------------2-44431235436667222544BA424244111111111119336112111114111166344337246A9A9AAAA9AAAAAA88AA88AAA55574645555559K444434444444444444445252552231344554542224322233332223221112122212122222222222223342223333434763333333536A46678974971274556CA5745533243341-273*5334-----56A463-16462323332333334-254423231C8-6556456F98EC243816544445A5A11111111222212121111111111--11221111-11111111-376634C94479AB9A49AAA77A5AAAA67E6677961167312322934-3615755668435345441--5537641258638A56437545335746664DC54523354343227845454443211644AB8424M7N987988889B8AA786DF9BL--3511211-111B8569C7EGHGEFGGCC-FCDDHFGDHDGEFEEEEEEA9A57978CICBBDDCDCCDEDACCC8DBBCB3-799899999999--3233333555532458443544566264236334332322288CBEC9DCA5CBBA29984222222221AFFB666657E9HH874444535433332145CD6677--------1-3111-1-22122112222111221113444456665-6G6 1111ABf-7434788CBCBFDFCLHLI99A999CDBCAAA9BABAA98CGLPVTIHE99999667575-75574766266677798566485B5754453658DCF28*A*ltdkjlYYTRRUWnhSnd**k4edzSZVVfUTfdLTPPIeWRoYbUaYYlqD*kLUmSVxFO*G1QB4O34343E76C9CD66ZVMX* ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.76 Alkaline phosphatase-like
[ 136] 11-2-312------14C1111114411451598p211-766B-CJ3B9A7BA8-143C7222682-11 w**-G-456666-123311-15112722222275584AGD11339B1--76-HBK31B--797-*5DLFB221111448FCE6--1--****2*GH1--e*Vue*S*f*--------------1232537443S8z**km-1-l32-7131166--------211C5D8M------2-----CA52A321-1377K7JxdT6RZXwsT5DAAC4Pfp11-141BOPMTPTQ74AAHCHA37AAAAAA-6221C-3-78-----55--3A6-1-2AA7732339583--4--1-3--41-1111215637414H32---323-3114-2222222624111116724289KI24--8A832277--12-1-1-*1m7451--1----A75---1112-44334333424-2262281493--54444467665756252D3522223441111111131111-2-11111111--1111111111111111111-34B4-11116966B8866666998888883A8898EDB--444313337481B815114-31----------22111J181113111322-1M44F5S11FELK**-3-----1111-----------1-1-1--2126-A73A4A4111222321115128-24---3-11-------1-31123BB5353732-B336369476E653235446662321-111123122121411443423232---22232122222---3----------1663111-1----------554454513-3D556559764575463332-----------12-----4222244FCCBCDCE1111----994444--------3---------------------------23221272121B-L --22**B12-1222-B7DALEHBHIHF4455553334343344555C968DEKFEDAB9989114-11-2--143-----1333341116887AE45442544222-6P9xbXWcWNLIFEDSNkbHXE**l4hOrCLJHZIMPPBPJFDbIHgHZOLPBJPBHPN7rFFnCGGEBSUF*6A6OALGDSBNO3VEDPL5 -----------------------------------------------------------------------------------------------------------------------------------------1--1----1--------111------------------ * b.3 Prealbumin-like
[ 137] --------------1---------9224-442212---4232357211--B54--------------- 8AD5*E68889674**yZZ-Z*66**ZZYZZp********4*M*bVGE9HG7KLLG4Y--UWW7*a****I344433323539313224321-221---1A313O2B84------------------22-1126-476681-2M3L39C671--11------22-A68C1------------9584421157DMNMNNJNNBNNLIHMFCHHDHKLN76BFB44444444WU11-------------223434131971-11166--45311315365-------51--------------------11---2----------B5BD776877925137DC1111611--7--4-HG85337634123-223834qKKL-----PJkPU638UMLPH5555544555H-BDJDGSFH6bS-cOOMWVJcefKNMN5I98EEB7CD9FG999999995EE478CC------------------------------4KJD24OIFPcejdgbKHGHGOOVUJKKKBIsIgRYXU11KIJ9B9BBQBNGSH5F57ABAC711111112349974rEJ62783BD777-273B77678CBCENQ3A2-----------1--------113622BB58KAI6D47AABA96A7C9A9D967877--11633------BEAA7E7CDCDDEEDDD-DEDEFDBCEFCDDDEBDDAJMJB966AB9ABADBBABBAB9BBICC9BBCD6-854666645767---51111111114FK9C2--112-1111-121MMNLOFA45495STQSEUPQKKHJGAPNP---------2788C78798BADAAHOADADC5561-1---32EE6755----------2-------------------------22122232221722 -------------2-----------------------------------1------------------------------------------------------------1-----------------------------------------------21---1---------1-----------1--7-----6---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.121 Tetracyclin repressor-like, C-terminal domain
[ 138] 226294345554555587454434734B7C9544677778777695A967KIG8B9ABB982231-11 ADI5W534445222DAA77-7A559J777778EEEEBAHD7GFB7B776763EJD47611BDE9B7CRRKA34445553476C5A4AB78E92H655--69594BCA4922222222222222232334454374BDDII444FFDAAB9988955655555777ABCD6353433453433CC977DH699DIHIHIIJLDJIIJLJDKDDFDIJLCCGHC78999999PY677777777777777645644231451422276226633334-65545454556544444334334454445544544554445534443CEBLNGHGGGGFJHJCNGGHONMRBD45I87HCCCGGEAGJGHFDFCA77D7A97761111145KEF9679B9996646665454A-98E88C8C9A61KEEGDDDHHFBDE99757865567A974444444466443C26221111111111222312111222222224558528DD65HDGJEG8A999BBDACCCC7ACDABAD934DCC988959BAABC56C9435832233323979AA96EDA7ACDAECCBD9HGECFEGABFEDFELAD4655534344225222212356689BA5569BBA7D777777747665567856679211B98611111179CA77799989888C8-999A78899A98799999AABA886889889999989999999977898897288A7ACBABAAA1137333335655C498644434424434344377777564336BBCAB8DFF699997BCB22212221245669675775655677696998886666128744447722222222732111-1-11-112111111--2111177989897B7H863 1222CG7-1-13YSJ99OFFDECAEAB8866669886777677877A98ADHEGGHJDBCBD544434345464555455444445344BDF9QEF678EALCbQh38C6D7A897778679788B7B7Hx82B993898D56C6367A7A64GA755879I7KDNFNAEW9B941221E1-1X386BBK7844CBED5 --------------1-----------------------------------------------------------------1---------------------------------------------1------------------------------------------------ * c.6 7-stranded beta/alpha barrel
[ 139] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----32------BGK****************************x*w****************p**exzLzdh*v*qsYywm*****LOTdsu*h*****xRP*YyZ-BQ*-----------------------------------------------------------------------------I-*--14----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.38 Zn2/Cys6 DNA-binding domain
[ 140] -------------------------------------------------------------------- JT*9*997776976JJJDF-DJ44IRDCDDDFQLLLWJWUGOGWYY477997JDC44911OOd6lJbx*oI222232221D8G33555gipe1Z771114T8IK*K*C*22222222222222133333433354MGGII223WDbBEAAA99BAA888B99897IADDA59555659555595222553HAFQQQQQINQBOORNOQEJIIGFPMRCCDMJ8B433444qV433343333333333444445224224222133222232232223123323331223333333333311111111111111222222222ERMESFFEIGJEJHFHCKKBAA9MJN44RDDFBXVNCHEAFDBCAFC743T3sUHHM344447ALHJAHBIBCMM5555555555C1HGNDJJEK9N82JEECLIDIKKDEEHACA89BC9EE89755555555555649HB2222222222222212222222222323429AHG49FCBBJJJKMJHGGHFHHMIIIIIBGNHKCFCH34CCEAC9A9N8BEI5BSA887FA43333333P678DE696244433864352665665956WSQTk*4A822212222222222222222422166796C9IGAFA7AAAAAABB999A99BDABG2-2866A22222274765786556655565-5765646466567566555555CC79655555555555555556536435643765666565665224C33333555534B7A4444434444444444343347222KDNPLOOWSVENbMJAEEE2222222225699977777B9977KMCDDDDBAB33332276BCCDCD2222222264488F21-111112111111111111152645444447k67 1------11----2----------------------------------------------------------------------------------------------3-------------------------------------------------3----1------2---14342K12244969G-64898---6 --------------------------------------1------------------------------------------------------------------1---------------------------------------------1----------------------- * a.177 Sigma2 domain of RNA polymerase sigma factors
[ 141] 444244444444444444666662IFHCHGJF2222222222822222222224244444446642AG -----------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------1-1------1--------1----1--------11-------1----------------------------------------------------------------------------------------------------------1---------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-11---------------------------------------------111------------------------------------------------------------------------------------------------------- CAFHaYT5lIGKXbYNOMQPRQQRTQQMOIOMOOMNKOMPJOPLNOHMMNMLTRMOPNLOOOPNOPPQCKWWOMKTVMUVSPPPPOPNQSiUOYXYQMNJMQLcjdDVuX*******ygppv*s**n*m***1***kwwx*n**xc**jr*vm*p*xz*elejjfnT*eh*QrgbKeaM*PONRVz***Q*gg*YdUbJ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------521-- * a.74 Cyclin-like
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o*I3IFJAC8BH7DGB6C9A8F8BHCCACEERcCIFFAGCFOGJCCCACC*CDCBAEFKMAFGHFHCFCH --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3---- * a.27 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
[ 143] 22A222337323FJG72322222322222222222332222223434622433234224251222212 8E96U98B778869EGBAA-AE55CEBBBBBAGFHGWYSZAPLSLICH8DF6EFI79944PUK5aFVeea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vD-KEO6658B69BA7A735A84FBD7AB69B8A974I77H56773533G22144624E3423353333 ---------1----------1-------2-----------1----------------11--------------------------1----------1----11------------1----------------------1--11112-------1---1------------3---- * a.6 Putative DNA-binding domain
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u*zwdWjefuY**Y*c***2***aYZX*YkvhWccXVsbV*a*ojrISWZYVkNsTViJTbC76B7y967AASZl*BgO777AA98 --------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------21--- * d.50 dsRBD-like
[ 145] 4413-6867788667846697A7E96663788C69454766778A78C5BHD955443356375A-11 69DAI64555545478888-8B44BC888888CFFF9BJH8CA647464333466953--98899ABCE98222222233AB7A9A7977756744---2A576B7839111111111111112FJFGGECFGCC867BB3339ALELLJFDHHDEFFFEEDCFEHDEHI3753333733437855543378A777776797777668A677887786889667222222A8444444444444444444454---33-------2233-1--1-2121111----22-----------111111111111111111111111975DCCCCCCCBDD66AA488895452873FATRJRG54CML56432228B7766D11111BCACD537A847955555555556-88B78D7D765187779A8898889E477A7776776A888888888B8866D6D11211111221111221111111111111339C4467777CBBCCCBABBAGGCFBBBB7BDHD9BBA3589785665AB7DB787DD486DB3333333234FCC4YsLJNMOKLNKKK2MHNBKAJACGEDF9HBY62272998874454444444A769AAAGBA667B579ACGFEE7EECDCBB99DBJH--299BG-1-111B7A9B84CCCBBBBBDC-CCBDCBCCCCCBCBCBBBCACAA976ABBABBBBBBBBBBBBB8AA9BABA21A999999A99991113111113444D8A7A5558375444365554444444344B599999998A8898B6776222242224CCCH999999DACC4433333333333355E6556666--------622-------------------------5464443444A924 22--444-83123333243544445442212222222333333121434455575444555554734634539454424447775923332324424332212957-7E3XOOEFT9AAAF8AAJL7L7i*H-RIG8B93CBDP86GAC8A97BCMB9K7BF8sJd7E676VlG6BJA7*23285AADF47B8495594 -----2------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.1 Globin-like
[ 146] 658577877888888655877764955859D843455455555345645AAAA335355655544449 9881322111211123433-34--55333335533333331323241122112231-1--2321322343211111112222444544445424112--3839775376--------------163123434167111--11131BMH8CB744443546758A5789782522222522121131122443556566566366657644335565733333333333333423333333333333354443222222222222222222221122222222211222222222222222222222222222222222222234333333333343434334555243223223333435353333333223327444734444544433333444444244442235-4444444456518775887AB9AA637678745555B695555555556664344--------11222233222211222----18565656657ABBABA8766699CA767777A8CABAC2367645777754463468563476444444433485457756344277222234464759623235924433433333334344444446564644994E7CA7FD9988887CA8887A6AA7891-3853711111187566878888888888-889888888888878888899966448A999A9AAAAA9A99A8877878742766666666666124734334444449778555434333334333555555557855AAAABACB9CCC99AAB85654663559BA677777A889887666666654444212122444311111111312----1---1-1------1-------33333333331221 IDCIKKG8tJJDGJHLJIHHIIJHHAHJJJHHGIJHDJIIGJJHIJHIJKJIEIFGKFJHFGGBGHHGBCIFBGDGHDEGHGGFBEIJJGPJJJJMJIHIFGHONMJIcHULMOKNJFIQEGUKUYCaF**d-VO*FHHIPGIRIHIIKIKEFQHJIKLJAEKMKIDLJKMDJKJKQMP*MLGQOuVZsGpQRJNNKIK ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.38 Sm-like fold
[ 147] 11A2D3326666666B43111118F4457395768778666665867888C99475566664314-44 6LY8G425333233FDD88-8F22HU88888EJFEF9JKL5D8IGA834542L8IA671175J4M6VKIN7211123374B5L3344455443823---4749DI5FAF---------------22222222222A99AA4445E6555662AB441111-1225B5AA611-11111-1-17893255225ABBDBC779699DB77HG7779D996E7B867677775ON35555556555555574434B2333424222344444743535222222322252222222222222333333333333352233322225IF5HCCCCBACECE5R774774BA8A2B63B4OG88764KCG6575143N5A8CCI4444457VVa545967B7CCDDCDEFEDG-IFLDDGGNDHI2QIIIGIDXQJRSJG7HEENJCDCDIEHDBDDDDDD9EE785672222222222---------------222248Cl96CED79HMNOMGDBBBAIISMIGGGCDTCSMRUO-298D8A823B8F8QJ396643661-------3455633B94426B37356523523632327658FD7914322----1-42333333311-2466E64382H92537788664I7656869B67A--17445------A585C74BCDBBBBBBB-AB9BDAABABABBBBABB6FEJ43437A69BA9ABBB8ABAB9964355551-96666666666623-B111111---48D4A2222211222221235554547142C5EEFEFIKE9ADBF699A32222222257BEI44444839GDAA6A8AA3333333--4D33222211111111----------21--------15---11149CB8544559543 ----651-221-223D5FBDA78FDAJ335555433533444444453CBJINL7683656525223511-153211111311111113BMC58A87867653B88-396KKbGTOE9896CDCUOBMCT*F-JBU7CDARCDDD9BC56DC7P9NAEF64E6C446957L77E5-54-j11235C7FFB6A11A3538 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.92 Composite domain of metallo-dependent hydrolases
[ 148] 552224ABA99AAAB81768766B83373556455445454444624546999633222226855134 77G5E7366665658CE88-8966DL88888C9AAAA8JJ455767534533DBD7781186B5ABHCC9444443331378B54242445334671116544495544---------------64444644464666AA1119E65745544422224332334576A3222222232222353551124779999A89C5AA998A6577679A977C57326666656758888888888888867786344256244368833873442465342222-1-33223334222223111111111111131122211113846C6666767A69577764423744162444GD68B52375224314234477771221298HJH437E99C9555555545381BAB99J9DCA61C6689CLCCBFEBA4859AD7669A9A9999999988744877------------1111-11111111----667A55CJDADFFHHGGECCCBGGKOFFFF9DIITDMIF46999C6788E978FE56A32237433333333239A84JB58323A743351B7A6B495698A89H7E221122222232211111112133343764685A364567778668668688876A7-114452111111A998887ABBAACBCAA-AB9BDBCBABABBBBABB7BACA9559C9B9AABBBBB9C999DA99BAA93-A7777776777711-134333445556CC93344531524343346667656468D6FEEE9E8B89BBC9B9B4111-21-1446596566556586665454555522221134664455--------5-3------1-111--222-11-1----24322333335723 5555BC8-J766669IGGAFGGHMINMEEFEEEDDDDFDEEEEDFFFDEIHKNTHHICCEEEBABDAE89DEBCCEEADECCCCAD99BBJBGFEE999A988D9C2DgLSKNFGFECAAACC9QJ9PDh*I-LFS9DDBGADGB7CDBBCA7JEADDFCKOBOEC9B89CBBIB79A9r354C9LAJLEECEGD9AA7 -------------------1--------------------------------------------------------------------------------------------------------------------------------------------1-------------- * c.31 DHS-like NAD/FAD-binding domain
[ 149] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------11--------------------------------------------------------------------------------------------------------------------------------------------------- 1111ywh-2113NJRA9C99AAAAAAAAAAABAAAAABBBAAAAAACCCCCADCCBCEEEEDGDCABD5DEADBCEF6EFBCCCBCCCCFPH9IHJCCDFFHFjhq4t4a**********************X************x******u******c***eboV*TX*UtaU21122--1228CGEBB311BA992 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.116 GTPase activation domain, GAP
[ 150] -------------------------33L-1-------------1-----------1--1--------- 3--28-----------------------------------2----2--1---2-------44--1--185--------------------------------3-4--------------------------------------A-----------------------1-------------------------1111121211211214211--116----1--33333344-------------------------------------------111------------------------------------------------6555555525---------3---------41----------------------------------------------------------------------------11----------------------------1----------------------------------------222224-2222----2222222----------1-------1----------A------------------------------------------23-----------------------------53--14--1---55562-12221-212--9-------------2111--11--11111-1--1----1----1-11111------11-11--1111111111--3-------2-311131111333---------------A---------------------1------5113111--------111734244323-3BC988887E959911------------------------------------------------------------------------ 45--BAd-SCA2CBLCHGECDDEHEBCDDBDCDEDECEBEBDECABHGEDDHJIFFIEEDEDA799992A998AA99599A99989EEFEJNHSMGJCBEBFCLKU2f*D*******wywq**r**h*i***P****pfw*q***t*owt*lk******g**WhccW*dl*SpbV1IJNSDEEAEQFQJEPGSYcz*zt ---------1-------------2------------------------------------------------------------------------------------------------------------------------------------------------------- * b.72 WW domain-like
[ 151] ------------------------1----1---------------3---------------------- 2482H645667213GIITT-TGDDgDTSTTTJJGFGA7BB1XBX2123122132323411TL62x4buEh334443331233222222766615336--45244934361111111111111133336543333433345222T257D555B1211111111221AECY41111111111111213322233A445455557555655332287556333421111111173211111111111111311311112232212111222212211122233311111321111111111111111111111111112221111222443333333434A4773333423-15322222222332323342333626755311111BDE796467B66644444444443-88K8AE9958317559448554546F562535232253511111111443216552212122222112333237333333212414375134424AAAA9FGEFFBCCABHIHH6HBA9BEDB24799A865587AA7767B2113A422222224454676764243532322213536348347777bK251112211111111111111122224438716667575689999A97B988A67888A1-25535111---9274242366A388544-64344443566543333334356394435333333333333333333334311455555455454111323324CDDE37E233333332111211126666656422956767AC676566657463111111113455D4335356844443333322222221123AA6677--------212-------------------------25422222321814 54BC**9-F53-87ANVmLoUXcw*zmFEFGFHTXKMTORPOOEEEZUTgdWYlPPinQMKLEDC89A5BC9A9DCC5BD9DEEIHBBE7L7V8D666667UBC991DzC*HKPOPOHIGFFKINOGVJx*K-RJhHEFGMFINDCHJD9ID7TLRMKFBJPDIK8JE7CJKKIL6DEAjECCBHGKDnfLDADHJIHH --------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------31--- * c.19 FabD/lysophospholipase-like
[ 152] --11--1----11--11-32222191394563321--11111146658--324-121111-4332-21 25A2A3322333-325422-25222522222247772444-626823544427644222222G4545B6542222222-2246122-299BC-4762--48258846-6I8DAD88444444424442322244266645-1-81894844445444424465746A67522222227222274465--6887DDDBDCDE9CEDCCF465587DCG65522CC4444442765544444444454476666454566664454466764564444222222222222222222222222222222222222233232333517477333222282434554868633541AB2-9851-314-1-211-27418A444-4444372445252634444244444444-886866647C8-766888A9EA8A45222C4767766225555555544444544----------1111111111111111114-454946D9DAOIKHGECABBBHHFEEBDD8BGMHLJFD22FCC59DEABEAAO576FAB48A44444444699CABE7645353352333299A6A876699G9IH45222222222225666555664313ABB8874B264648656456676664B477494712746C22-222BAA88A8AAAABBBBAA-AAABAAAABBACBAAAAAAA9998886BAAAACAABAABCAAA88AABB8B6579A96A99B676444435333444438666222464222222224AAA669A99BA4GIBDAFEEBDDCC9GEG6683676664666877797899D8AACEDEE8BB7767---2444444----------3----2---22---222222-2222233722222222D42 3345QP6-B55-355DDEEGEEEEEDCEEEECE999BBBAA9BEEEECFFHCFDFGHFFFFF666666266466666466633363555BF7D779B99BAC7KHL4JZDLVTWZVWKBJBEOMbWEgLw*R-XOeDLIEPKMMG8MGIEMDCTKIIKICDG6D898PABECI755135X76775XaehEYI99ZlvuB --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.136 Phospholipase D/nuclease
[ 153] 11-1-12222222222-21-11111---2--1-----1----1221111-211--------233--11 21539668888777BDDBC-BC99DDBBBBBCCCCCCDDF4A9FC98669A4BAA568339897B9BFCF79888AAA3-164333333334-343---22122434231111111111111122222222224277777223A-998566534554444454658586424222224222296744112221AAAAAABA3BABAA9342221BB9322824388888846-33333333333333433325A879976799BB998956656754433384446774444444444433333333333338444534445233482223221323124322226252-5332143222--2-12222344314677811111336664334642533233232224-7887875859719555BA5887777479524422227768888888855557343----------11-----------------22532222222777777777765577777757757768513666785554565756653222331111111333453447234242523334313233432224266-431111111111-1-------11223333224535273353333252355343333531-3233411111156546557778777777-7788766777777777776776544446666665676666666554577772164444444444411331111122223662433334322322233355655452454233336665456655665112122-2121112221223433355878776663333-13244555511111111312------1------------------132--111114311 6688DDD-mLF676IPQRPJNPOVRTNFFDFFFGGFFJGGFHIGGFRQJKOUSWMNNJHGGGEFIAGCAKGCGFGIIAEIAIKKHLEEEJbIQDIGGFEECIJGCD1D*HOSWRUSVJEJKJKHkfIeM**Q3eSrIJLLSGJQIDJLHEMIEcKNIIKDHKLLDHOdDNqXbFB9NOI*JIHEHTMLVPSYbaYbcXf --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-1-- * c.60 Phosphoglycerate mutase-like
[ 154] 775554GBDEEEEEDF8ACCB67A78673776447778877765737446676956466653558377 4656633444345444446-4455444444444444446486664466744455565544777455467755555555565756876666655566333444444455433333333333333445555655545999774448777766666666444444666599C6445444444445555557726989998999979A999A77888899A999A986666666BB6887778777888767786672524426222665544553444666666666666666666666666666666666666668688756678CB689AAAAAA9A8A788877795A56B7867888898689B88996655754434323334445664764445555555545561444444446543755454555455443334434444444555555555554585444222222222222222222222222222344343666556665667788866558889766755455554576556676758565885655545555556675665898666676666647887779B5A99A9979444555555653533333334553577665466755566677766777766776666323777934344466555659998988499-99799888889878998886665567666866686888686686999999952666666666666334633333543557767777676566666555666666666666897969878666677775444444446666556666656754444444444444466964444444444444463422222-222222222222222222233433656665544 8833AAA1P8A254C98A99BCBD8DAAA9A99AA98999889A9A899A98A99A999BAB8555554697564774876245666667K88ABB67885969C82ESBNJILIFRDDFCCHCVTCQHs*I2PKTEFECOFIII7FGD9LFBSBGHEEABDCJCL9JACG79LA6DHD*9E9JHiihuAxaB8CFBB7 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.68 IF3-like
[ 155] -------------------------------------------------------------------- RLZ-3-----------------------------------22221---------------3-----------------1-11-65677MNQH-P67---6M9DCWCO8F--------------697AAA699A99ABBGF---21IFBHABC6566322447AA6NEMX5152311151321-41443351-----------------1----1----------------L3---------------------------------11-1-----------------------------------------------------9A42G111111121312AA2--1-11--2-2B299C996444B1125131I8TWAAG55557PRideO9MbXOOJACDFAFDDDDN-QZOOUYWaCLG-SKKLQQKSOQLMKX7FDC5HBADCC6BFFFFFFFFDOOE9EMI1111111111--22232332122221-1136CLB9BB95EVXYWYQNHGIHRRPVLLLLBNWPTHTPd-4GIOCAAFHTJDFD7FKICFEDGG4444444DCIDFK2BH657FB6EH88B1EFAIEKHDIIJCJFHBHA32233333332422222226524AGGIGFHNDNDKD9KLNNLGLUSMMJPKSUMTO2-2GB5E------HIIK9JCIJJIIJJJII-JJIIJJJIJJJKHIIIIIGQYQEKDEECDBABCCCCDBACAABLGDACCEH4-HCCEGFFBCFGF--2788678FGGHJELCF555344233331113LNNPLEHBCBCCWXYZVYZSHUSVQGJJO764636536DEMMOAAAAAJPLONRUJGKGGDEE545411M1664444-------121----------------------------11-11111CK95 --------------------------------------------------------------------------------------------------------------2-----------------------------------------------121--3-1-------3--------------D-----E---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.46 HlyD-like secretion proteins
[ 156] -------------------------------------------------------------------- ----3------------11-1-113-111111------11-4-4----------------23--9-4916--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------------------- ------F-----A9CCBCCC9A9C9AA8867688857A886887769999GFCl7CABCEEE98989857978A778588879977434BG8BABL989948Chcr-X--*********un*****m*****5***h*so*m***d*vsh*qc******dom***oc*lz*Os*R2832314126****B*s555967- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.38 HLH-like
[ 157] --2111----------1------111122411111111111111422233232155434641223133 1413B125446112D8867-6C--AG666668BEEEIEbU46393114-11-967332--B661568B8521222111213212222133333333---522353153122222222222222344445344534---1-222114213221111111111111122221111111111111--1--222-263333333323333334344453331334423111111222222222222222223222421-----1---------11--111111111---21122222222221-------------211111111-2214955565568582333466525242122332254322234443122112653311111146D8F3148559622332331334199D89H7D1412644232754479BC111358322335944444444822243321111111111----11--1------1-11-228326EAAED9AEAEDABBCDDEIBBBB5CLDMDMII23B97B9485D9A6FG4A77735534565555442CFB13334436334444143432353444547833-----------------------1-668785A48597887777479777676AA69C2-1563721122265564568776866688-7889866878768778778BBB675667677677677777777777666673168888888888822241111145555769A333324111111111ABABB78365E5EEEECEABCFHGEA787311111111369886666678788668888845533332132552222--------211------------------1------42333232224212 4323CC9-cHI4BAOTSWMUUTSceWSHHKIJIKMIIHGGEJHIIIQNSZkjnpUaZNRMPONDICDF7GBBGDGHG8DHAPQPIW9CAOTJSGHGGCFDAFEKCI28pLUEJDIGQEGGCFKHYSERIx*N-ULW8GECOHHKFBIJFAOF9jGJHFIGXo7JFO9GCCO99GDADCB*CCADGTNilWaVJGWQVaJ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.25 Ferredoxin reductase-like, C-terminal NADP-linked domain
[ 158] 775375556666666658545554A77A79984332222222376356455542795355A8567-56 A7C5C556665555A6688-8955998788879AAADBBC6C867663556599885622DAC5F9IDBE644445442334854544555526--1334858765678-12-111-21----1555556566558889944488857855865575555566667BCB5555555555555A54445544779999999969999AA9677779988AA6633444444B94777777777777765555743-3443422-442234132143545222222254444444444444111111111111153455533325C8476666776766578843337563245585986B6559766554354A568778-22-255C9C5668988A46554554459176966B7B7G61A7779CF9BBA8898889A66877B8C5555555595555768----------111122111111111----466A656BB67CBBACC9ACCB998EDDDE8CCDA8EA84577957ECCBAD9CA4485655974444444456757478486567865541666676985AABB9F6776656555554353333333755564498576794A566877786B666666A76881115666321223B8C87A89A999A9999-99999899A999989A888BBBA9DB8A9AAA9AAAAA9A9AAD98888897-C99989999999442522212444455D89555544144434454B9BAA8768556CCCCCBDC9CBCA9CBB644345544667778888888866777777778866663464776655--------2-1--------1--------1-------35665646864855 --1167C-8421669BBB9FEGFLIKEDD8888DDD9DCCDCC9AB88CFGJOKCEDA9B9A999787786688877788888888557AG8B797988658AA9B-Bs7Z7D99585244855IB3A6Jj6-9693666A867656554753D8A85ADGD5MC5A4345CHN79CDB*BBBGDIISWBQICDKHGFH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.79 Tryptophan synthase beta subunit-like PLP-dependent enzymes
[ 159] 22222222222222212222222221122222222222111111211133222322222222222212 6775677888877755555-57555755555577777777567777857666777765226667755666645555455556665667555547474325767575547255545552445555444444444445556644455777777577777777777767767678777778777766677884B997CCCCDDDADDDDDC99BB9BDDD999B9AA999999BB8888888788888689788879B99998A99998899999887899AAAA9AAA999AAAAAAAAAAAA9AAAAAAAAAAA99AAAAAAA8CCDDDDDDDDDEDE9ADDDDEEB9A9AA9986888A66878899995AA756999866656787776777777777777777777198888888787587778889A98877987566666666666666666777767774444444444336656666666666333447777687767999A99999999999999999999999977999AA9999AA998AA99BAABA99A99998767AA7565856777777667778768789989B766666666666666666666667667688AA879AB68BAABBBBCCBAAAAA4BBABB416666655555598888999999998898-9999999999999999999999899999999999999999999A99989997398889888899944575555555555878A777767777677667777677788777999988888488868886666666667A99BAAAAAAAAAAAAAAAA98A9555555766667665556455565844446-676564355556445666687477777575656 55336521D442334334444445454552444332443544455544433333344443233344441552344353334444337553733446434444455725S67343263332433468151DK3-5332222432311341322241223844448263665B2355998A*BBA56BBDI4AB9695557 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.66 Alpha-L RNA-binding motif
[ 160] 33233324333332235454544493441458366222345449A49A66FDC122222232416-98 6Q77b-13334322aTPFF-FR44QVGGGGGKXUaUWSns6bEgDI352743CGB536--IGE2O9ROVW812222222248C555668964-733---24355B575411111111111111----32---13-777AA1-189FBB8BB866776666668864HHD44656444646547495611463466665477366567648A9564654646333333332C5133333333333332443221222452121244--542-21234442221111--1111111111111111111111111211121---2276ABAB99ACA38345882222B3F114733256696233561111373526H7762222267VNODCBHHILH3455465665B-HGLGGIHOFKD2KKIJLIGNMNIKEC6A86EEA8AB9784344444473326C8A333222222211223232222222221222JLBC2AA998EFHJGFHA9A9GFIKCCBB6ALDVERIF34AA9DB877A5DBF67D98767A43333333112BDCABE873DB3DFDBE-KLLDGBIBDNMJPHG7D645534444433633333334425557775BAFFDCA569777A98877767877591-14548------78983856776666676-676877687775777677ADEC984577776787777677766B556666632844444444444222311111353335J7A666134533334335878784A334AAFFEEIEGFGFIEE8BCB---------68779AAAAAEBBCE876667646521111184663366--------3-------------2-------------43122353333344 11--223-211163BCCCFBBDBGKGH9A78886678868787999DCCHFLJJ99BAA878769456365475766555777767444AH7C8D9BBA6577453-3I5C4543322343332622324G3-3342333333331315432-32423543-16223715D21323988y556DDC8JICC8B566755 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.45 Split barrel-like
[ 161] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----GF*-----1111111111111111111-111111111111111111111111111111111111-11111111-11111111111111121111111-11111a-4u*********************5*******************w******t***fVLa*hh*o*TT---1---1-232441522135341 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.93 SH2-like
[ 162] 333111A989A9ABAB1154432431113122----------------13231----1--13113-11 54D8J423664353977DC-D955HJEDEEEBCAAACIRO4DAA8B74444288872411B9K49ESEIE711111112223C33222221112111--242429372311111111111111134333534436AAA88---4A5745674454455555434466585374333353343566661134266666688656767877633366696765521111111661111111111111111111121123422111221122111221121111111111111111111111111111111111111111111111A42767677876451533333363132322417725541375112112153493462222267JIK759AFCDA7767777666A-EEHCBMEKCI82E88DABMBAAILC9452DD999ABAAE55555555B5574869111-----11111111111111111111142BE33AA99AEBBGBG89999BBNMAAAA9AGCUHLKE37BBAAAC77FBF9EF6885332564444444665E883AA48456584666157835334588789A373112233223233333333332224776327736282334444336444444354441-1866511-11143225349767978898-79998889897899989944543245333333333333333335434444511355555555455111212223566674888333322133323332444444448674BBCB8C978879A7A8953424522322229333333433366655553343333334344334411111111321-------------------------14433131116522 ----CC4-A52-456PK*ioXbNzotmKJHHGGLMNEJJIGIIDEEdWSkjq**bZchKNNN344354453354544144455574232GYOKPJF444568A554-AjHR68677G6654696EM5B7DW8186A5674956D466666H45G6B99EBKV6GEADABKCBACC38D7q554CCTRP*ntq66GDCJ8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.145 FAD-binding/transporter-associated domain-like
[ 163] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------********p*v*****u*****7***p*sp*t***g*wec*rg*r*******9W*WJZTRoDQKK------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.27 FnI-like domain
[ 164] 88776855555555555598975A644634556567A8678879857858777BFDDCCDD4446556 6882853333333246644-4733654444456777474436374432366233333411765354667653222233112257466644542533111332346443511111111111111334433433453BCDDD222A67568775666666657676587877555555555555899AA4435565566666647667756766896676465643433343A444444444444444465557524-33211226622442221233335583434565555554445552344224322233566333666334245222222272732334333323135443733655442535453233675655765555967886776676677677777776-56555775685476667766676667466887778767766666666555546662233333322232222222222222313356575545544888889878888898888888A8B77783487778666677675676956554344444466657798A786876857774888778797AABACB571231222222213111111123443BB877786658869AAAAAA7AAAA8876A672-3577832233378546756676677777-766776877787766666679755455767777788776767796665565428777877677871135545555656789685554544555554455544545566869999A9989899979893222222226679B77777A99A87777787777666634624444553333333312211113--11--11---11111-22237444545552732 7555A972K764899ABA8AAAA899BCBBC9BBBAABABABBA999989AACBB99B9888878777368779788588777777888AC9B9AD777898ADBK3BbBLMMEGKJAFEECGESKDQBj*M-SIYDEEBJAEJECGFBBHB9KDGKFHESKCBCH8MBBI77ECBLKI*GGEIFKHLUBUHFDE998J ----------------------1---1----11-----------------------------------------------------------1--------1-----1---------11-------------------------------------------------------- * b.122 PUA domain-like
[ 165] ------------------------2--1-3-------------------------------------- 1-2-*-1----------11-1---1-111111-----1---613--1-4---11---7--43--a-1FHG1-----11--1-------1-2---------6---L-1---111111------------1--------------6--1--112-----------1------------------1----------11111----1-1-11--11---11---2----------D------------------------------------------------------11-------------------------------------7-44411144514-----1-316-------11----------1------11-----------1---------------------1-2-2-----------1--------1--------------------------1----------------------------------1-------1----244444--11444432--1--------------1---1--------31----------1--1--------------------1------39-----6-2222-2-2--------------22---B-1-----112---2222----2-----------------------------2-------------------------1231-1311111111111111-------------------------------------E--111---3----4--------------6-----------1--3-2-------------11111-1--11-----------------------------------------------------------------------1-- 3367N8l-62-197965775766969644444434444444444448ABHAA9877A88767455455157555577277555555666DdF5jLNBABV596mix7HAS********z*************3***u********o***q*sl******ji*uvc*KwOWmfcnO28C1711111BLOx7Mi85LQThC --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.42 beta-Trefoil
[ 166] 557658897777777796BDEBA777B587CBA49563344355C77F448A75697965343294C5 44C2E867775443CFEBB-BB11BGBAABB9BFFGD7CE3EAFB59656558A85972244G755E7FA4B8779CB23D7-32653934315463--8233455CB32122221111111125747B6826237EF*w445A6V**s***IN67334333Tk5*qy*C342235435224318MP2244B23333325534453343644344447C6334364224267822222222222222322424225346227233223424532334333363443343335333733333333333333334333333333D554543454467555377449455B445A865GCE5AC27A5983A163777A8983A83M554575669C8AC33333332333-88879G78534-533656495363452283465465545323333336332348611-111111122111111211-111-111-847954533553475363333554A4244365952444--56474663A6498494D34424777566563647652536624744244214697769453543Eh7C3221323225243638363662275A75675615744659676566855766548543-4837723222266545777886887986-978865877886A788676576556689757565676687875A66666674254445444456422954533588579483476855846755B544435867655463447554775AB665557356364555265776767776566547678765444341-634444442A65111132664D531321352233322612211-27326323343632 6645ED93K765777465567776666666666767766666666666776676457666567866662666666663566666677774856565766658575459E8Z67BAA775266A6AC6F7P*91C8D3644B66C537752633C653697A58kKJ477EC67P78769bBAC9899BE5E7667I665 -----11---------1------11----------------1------3-1-----1-----1-11-11---------1-----------1-----1-----11----------------------1----------11111---1--1----1111-------------12-1- * c.52 Restriction endonuclease-like
[ 167] -----------------------------2-------12222172134-211---------------- 3CC-J2-54442223CC99-9G--B8999997FCDC999C396A7722433-43512---857-R9CJKF7-------2-2161----2211-311----3-234653433333333333333232244237443WYZYb---u-D8AB77655334454557A318CB9233322232332112----114B4444444524445445577BA544264462399999843111111111111111122121----------------------111--------------------------------------------23213222222222222112222223112326332433421151132-1-1-22111-----559B97134222711111111111-835333264321533423243423374245256555373222222221223-C35-----------------------------3126212434244454563333547B33332343448571-2226453374534387B6314851111111121467288453882DF997354453242645A64*3531---111111---------3232311764465433446555555565554545666--24567------24224232222222122-2222222222222222222455333332222222222222222522222221-412233323333---111111444463A58111222111111222645552422267666678767777797773221222225554677777565BA23778775551111--M5PPLKLL1112122233--------------------------32-22222222321 658BDEG1YE5-9BF8998BAA9B9BB7768679987777777788789ABA9C9A878777CA887847A8888AA59A77776989ACM99B8C78787CBPLO-I*DaksgjjlRNMNSVP*vKsM**q5zi*PNRNoPTkVJXNHHdKIsOcWUbLPaGbJ*pt**qKVIL5MH9*DDDGGXfj*9sLTOLKUPN ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * c.13 SpoIIaa-like
[ 168] -------------------------------------------------------------------- -----------------------------------------1------------1------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1--------------------------------------------------------------------------------------------------------------------------------1-------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------1--------------------------------------------------------- HF8HadZ7xILDTQXUWXVQTTTQTRSSSRSPQSRSOSRSRRSQPQQSSSQPSRQSRRSOOONIIGHI9IHDHIIJIAIJIHIIHIIIJNfOWSRROLNPJNKRPU8W*d***wy*rlirkjyl**f*g***3***gmjo*eo*ibmmlfqkq*lwknwfgZfsobSxaekUbweKSQN*JLLVUmq**T*eNOMPQPQ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------5---- * d.20 UBC-like
[ 169] 221-112----------122222253445464211---111114334345746234334433331-34 6494833644534385588-A94468867886988897A858898675545478864433769587CAA6632224223334744444879925662--55565655752222222222222237756665457644444333346786666446654544668456675344433343443767554437558888888B688876875778677655587564444448855555544555555555555434445452424344553345645455554444444677666756672444444454434444554444467587777787868657875555558546766566655566555546334446444233333455754355655444444444445-66475676574385467696665535343456544464433333333365534543333334433111111111111111333325575534444444653543445566575636545546534334475557545638533333533333434556436655674656455543675764876887899653222222221212111111154223336763434456656667767778877666763-3643333133356655655DD8586A55-F75A68A799F996665666966586655656556656685556675767753677657777566333355544565563666555665555556555445544544334656588465333545454444444444666786686777865556665555333344623333332212222231411114-122122111122112211143344545556645 3334KGB1G784EEBCDDA7BCAA8CDAA7A9A9AA8B9A89AAB99AAACCCCBCBACABBA89999699A7A99A6BB9899889AA8FAD99EECD879AGCG3BJ8IFNHIMKFEH9DOEYLBYG**V2iTaADDBLCGOIDLGDDND9QAMCCDCAC8HCA8C8CICEJAAFDF*DDCHFTIQaAYICCDCBCB ---1---------------1---1-----------111-1-----1----------------------------------1---------1-----1-----------------11---------------------------1111--1111-----1------------21-- * c.97 Cytidine deaminase-like
[ 170] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2222----2---------------------------------------------------------------------------------------------------2-*******qruhq*n**w*r***1***s*s******R*iYe*eV*t****8KNT**C9DB6C56**-**-----*--------------D ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.170 SRCR-like
[ 171] 333322344444444422554AB3F9AF58A854856AC9E9BHCIDLJ8kY8233354634331-35 22529EA8HHKDDE76866-68337C6666678777BoHO3D9CB8748864975659449A4FKCE8ERB23333222436B31233543556551--1333243472333333333333333EHBICCDCDIIAGGGG329E3MFFHEE7DC66877877FB8ATaED676766786766DCB7733149BGFHEHGEGBHEIGHFFEFFEDGIF999T965AAAAAAXV7CBCBCCCCCBBCCCA89CF813144132227634443122515346667666544666666666655555555555555845653444439FBIDDDDCDD8F964ee476688463833B9UNE72D245654352B5794322344344BD8AA457UHEGJ5555555555B1A9D999AB6843CCCBDFFEFDDDA9332BBNJHLMB7444444444299429HM222222221122222222222222222221322275444467778766888667A77776789A44451244598433AA755533C33237444444443335BA3GI3648569C99818G89777EF4488756D44862434462223323322673339968A383223323566543654464566674--356F41-----L6IC6CA688B6ABB65-7675A8A5977B9666665CGEKIBB98787788888878778E659777751DCCCCCCACCCC--4111111111174C9F7676852354343373344333246K389788B8A8897788992222222224A88A77777CAD77221111111111112274443343-----1-18221112---------------------22333343336333 12--111-31--22211111111111111111111112111111112111111111111111111111-1111111111111111111111111111111111212-1H121121111212111221112B2-2131111111111111211121221211-12131311211212543L3425493391464437326 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.92 Chelatase-like
[ 172] --2-1-1344444444231111--4--5222---------------1---31---2-333-411---- IHK2W35444423-44533-34--643333354666235548469FA3BA73889525--1295J25NK9597775CB2--1811---DDOF1D11---6I157L5H7911111111111111222333333343BDC88---E35FF46635322345444241657A6222233322222B983478-4A88888887758788876EBB4A78876715BC899894-W533343343333333111535861781172899226824346254444475453555555555555532222333422223332213334621BF4444444B48C6441CAA81682-5E122212--C1-14559125118E771-----1558534257556------------56B45866655-677AA95BAA7841823142797642-2222222242214276------------------------------23-3114344677466823334459323332554443---4448-3---2-6A1--624131-111111-1145512222-412131111-4341111-265559B14-----------------------111187871B4-B3B5544447-444254-42-4---5112------7C433737887866687-76789778877687877768985511-A7789AAAAA78A88976647887--677777766777-------------3-919333444-22122222----------4I3343343453333733311211211113669555557978853EEEEE899------41221122--------2-6----2---2-------32--1----58844949CB4M56 1-4598T-2131247RKOKQVXRWUUW8877574444445455465KMLNKPOSNOKJIEFF4382563332819794D73666489CDJJLK9KEC8AA4I8767-CLAuIcKSUJBC9FGIHOUBSE**c2QIcABBBJ8DHCBEC9AQ85QCGJOEJd*DPUJFPIVBHJFG7CCG*DECHLYSjYNMQ12HEDJA ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.71 Glycosyl hydrolase domain
[ 173] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------1111111111111111111-1111111111111111111111111111111111111111111111111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5344baO-J7B5BAI8577677777777777677777877679777666566656665565555544414434554433445454556668557695555666FHJ4PcR**********t*****z*****G***p********f***t**c******Wiy*lpWW*Yb*Zu*Z2655Y44445GA9J7HN33EHGGF ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.40 CH domain-like
[ 174] FD458GFHSRQRQPTVH4HG787S968E9JC63434A444444A429N457565LGEPg9B545B453 FBJ66312111311345nm-nA2244okono37768634457D8772A2232343222115453545445211115332274243851112212113--3114111F8322222222222222322P57F13K32277BE11152GTLPDHu2389723432QL2ZENI3222232223223346EE23295333333333333333443333334354253343333333333333333333333333333212122121122222222321112221111111121111111111111111111111111111111111182324333333323222333332223223143I35B4IB538K45693113B3M44122112782656339HB9A22112122228-482454C46651D559ADKJF98L691134496322422999999994586227711111111111155BC2675615611111123861233239ABBDA623338863333333A8987B72534687874BE856E44F4232222321222I44H54232D127115122214A4933O33334449262211111112222222222222143FF2446422333235333343333333333231-3D37E11111132332232221222332-2224332323222222222445424634224323323354443622232222143332333342311924434422332233355511113332341111111121115322423224332233864111111111222233333332323449595444462421143CC888611111111F1111112-112111111112111111127311221111611 7555AA81N88587C89BB778786898878889878989A99788BA88989979988999BAAAA97AA9A99DC7CBAAAA9ABBADJC9FDoBBDBACAFBB68P7RHGDEJJC9A96C9IHCMBb*G4LDM9BC8B8BFA7DB98CC8KACDCEC9CAFEEADBEI79M97999f9A8C9OAFGBGE89AA8B8 ---1-11------------1--1------------11111--------1-1-----------1-11--11------------------------------------------------1-----------------------------------------1-------1-1-1-- * c.120 PIN domain-like
[ 175] ----1-1111111111-122222-2--3---------------21-13-------------1--1--- 13A3E3343333335DD99-9533F5898889678793E84FCK4763645799B333334454434BA84555555433373-----1161-311------------1222222222222223--------3--DDDPS---E3dFFNDD9AA22-1-1119BM6DEDF-------2----2-1--11-------------------22----------2---------42-22222222222222--------------------------------------1------------------------------------1115311111113112-11111111411-141-22222----2111---53-C----------2111---1------------------1--2--12---111121322--11-1--312341--1--------2--------------------------------------111-122-2222222-2222-143222212314434------44523435353228-231------------76693-34------1111---1-----HHEHo*-4------1-----1----------1---121-1A2-1--11---11-----1-----3--1-1-7-------1-2--2-11--11111-1--1--11-1111-----1---22211--1-1----1------1------1--122222112121---3---------1-9-1---------------111111111117222211115111-2221----------2121111112321111213113321111--2-111111------------------------------------------------1- 8678PMG-SAC3CCL9AB89ABB98A9CBBGFEBC9BC9CAACB8AA8CDA9EBCCDCCAB999BBBA59DB799CFBCEBAAA9A888CHBAABDB999776JMO1I*B*******kVecfid**V*Z***D*x*VdcWualviQnbWU*aV*c*fhrPnxObXUMlORVIWZO3EDEcBEAFAIJRSBMB97KPONH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.26 SMAD/FHA domain
[ 176] 55352574667665676289887AA446847733632555554675ABA5776365455652333133 4572B1133331-288877-7D11AB777774BCDC97BC55583331432-647212--767576A6C75--------6aQ76663611111211---3421254523--------------14467564764567766333746552554222333332244254444-1-----1----55255---517444444343444444448838443345211222222252233333333322333322322------1---12-1-------------------------------------------------------344221111211-1123111222--111B-135wr4556-69B11-32-13546444111115ADAA9487E7C755555554546-BAGCBFAHA91189978886B988B953463756566373333333383315B4611--------11111111111111111111344615A968B8898AA9AAACCBECCCC7BA9CDDEB-4BC98B788968AA6A877766673333333112F992DIC68CA8C988F-AB9D95B46CB9B9C7H6BB545466252533333336D67777A755467242878CCB3DJDED9BBEEAKE1-14B53------HCCBBE6GHHGGEBGFG-EGHHFEFGGGGGGDGGGGBFFFCC64DGFHDFGIGGGFGJGEFFB9ACBCC2-A87899999999--1222222333385795666966343433556666664566775BBBBA88688888C8781111111112488E45555BA8676657577555444412715533331111111111--------------------------11111111114332 3322FF2162226787ADB8BA796987758457777767777534DABFBBCH9CA88888345443455436432323454544332GgMAIWG898DGOJNIS12973564562333235395263BZ5-5451332634424443242344745424536683634845622F94Y333OCl***Cji24JGIG6 -----1---------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * b.52 Double psi beta-barrel
[ 177] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 6644*wX-M892OLV88ECFFFCHGEEBBBCBCBCBCECCECCBABDDDDGIHIAGGFADDB98999947A999A8A5A99AAA98B99DGC8EFFBA999A9GHI4jmo*******xnnXt*q**e*r***6***Wuqj*rz*nVyqli*nS***tw*Y**blmaZ*dzpNO*e47AA*76757Vl**DsJB9EGHFH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.109 Gelsolin-like
[ 178] 44232422222222223122222422222222222321222222121231111522233321111111 7775767777777877777-7766777777777777A788555557877776777787336766789666798888885675543343777746564118B9A87756633333333333333766566666666666551117587666666666999999766766678888888888888888866577666666666666666666666666677766675666666666666656666666566666656666665556677666666666666666666666666665666566666666667666677666666656666666666666666666667766576676577666666667686576675888888768666666666666688687888878-77777777897488888888888877887565555545555555555555567973333333333334455446443443323357767777777777777777777777777777777777777777778777777777777777776787777777778958577777777776666676787888897585545555555545444444465558669869AB978999777788877778788788215675621122299999989999998A98-99A99999999999999999999977899999999999999999999999972888888888888225755556666679789777777767677777878888888879777788887888888887685775866899888888989997777777777666644738866665555555585632326-655364366665536666645444555453758 6744983-M86223133331111222222122211122122222222222212222222222334333233232344344332333122---3--------11434-4X475546644445354834737Y5-54A4342444453334344243444345344142444343478GJHvEDBBAA8AF39BCG9J56B ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.116 alpha/beta knot
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c7GC9EGEIHI9D96685s44656CBMK7GG6675656 -------1-----------1---------------1------------------------------------------------------------------------------------------------------------------------------------------- * d.41 alpha/beta-Hammerhead
[ 180] ------------------------1--11111-1---------------------------------- 1111122333332321-22-23112222222333332121111221111111233122--1121411233211111112121111111111111111--11111111111111111111111111111112111111111111112221222111111111112111111-111---1-11-21111--111111111111111111111111111111121111111111111212111221112211111221211212221111221111111111111111111111111111111111111111111111111111111131333333323221111222111111111111111111111111111113111111111111112111111111111111111-11112111111111111121111111211111122211111111111111111111111111111111111111111111111111111112211111111111111111211111111111111111111111111111111111111111111111111112111111123111111111111111111111111111111111111111111111211111121111112112114212211211121-11111-1-11112111111111111111-111111211112111111211111111111111111111111111-111111-111111111111--2111111111111211111111111111111111121111111112111111111111111111111112111112122111111111111111111111111111111111111113111111-111111111111112111111111111111211 4368dlL-VDG3KKPQMPLMNOOOLLKNNMOOOOOOKOMOLNOJJJNPQPPLQRfWMOQMQRKEHHDE7FJGHIIDF6EFGIGIJIPKKGQLMNHNJGKJ9HFMGH8ZZa*gogikmZTTSZfV**N*Q***A*y*VUVYnQcnQVfZVOoURxOgabcPjjTcZfMfPHiHrYeBFMMuHMKS7STcfQTRAGIXMN8 ----------------------------------1-----------------------------------------------------------------------------1-----------------------------------------------1---------1---- * c.15 BRCT domain
[ 181] 33424464566655555733333132232323334444222222223332222333343225333-33 9A85A33344423245444-43335D444443466645BA65637C442645A4A22A2298568CEBEC532224336222644444336423332--3544475646333333333344334444555444564556623346653644423444443443433333434434335233297544776239445465665566556D988C85557487957CGGDDCA54888888888AA88896689I963AB3393ADB22BF54B347BBE3335444433544555454544444444444444467222666A462ATAAAAAAA8A63H33475654372734322232224222649366554456633333332758444534548888888788F-556566569H42F88AAACDCDII7445358B8879798444444446664455511----------1111111111111111143553567777HFGHGHBEEEDEDGEGGGGCEIIGACC94488B74755A69AAC55456568466666662434443543344434554464545544644434444544443555464444444444544455596A76574A5877666655777656556552-44443321333JD89DFADDDHDHGGCC-DECDGFICCDDGDEDDEEDMILAA9BEEJDADDDFHCEBHBBEICAABBBB73EEEDEEEEEEFE3363666564444749B77786876676598983334333333B588989B9989788688866666666649BACAAAAA999BD6744444444444433564455551111111112311114-3143611333162132---2A6435D5557933 2222346-62213333333444444543333335443333344333333334443333333333333313223333324333333322224C3322322242234425438668746365475575588Bd5-658346563446634545649464286FF37423B23I35A34223a22243C76F46F5982235 ---1----------------------------------------------------------------------------------------------------------------------------------------------------------------------11--- * c.80 SIS domain
[ 182] ----------------------1--------------------------------------------- -----------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3112BAH-7311B8C65565657636578574757558488883554534657755664423343333233333333133333333878B885A777455365CFI2m23t*******svm*****u*****E***puzq*k***f*vqm*fd*x***yOt*jXWjM*WZui*cP11217111-2AFG*5*63235543 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.49 Cysteine-rich domain
[ 183] --1-3-2355645563381111--1--3231-------------2-------1-1131111333---- 7AD1J-2211122123444-4711884444447666337522147A62386-B79225--4458528CC635333698321-5-1-11DDTI1933---7D-75C37-E--------------12212222221244477---31225433222222222222224688412111114111143111781631111111231111111474422111223-144CDDDD91J12223223222222221112F9938734768CB559B3688748773442324533344444334442222222222212367222634283-9B2222222322C72249B8F242--4A-1--2---B---77781113-5744322222653554--11-2333333333333-87688666281-688966597664-231-34655352323333333334433--3-------------------------------22331111178868571111445443332454A3333--8873331114526444-52143--322222343114---1--41--1------3---2--222229--1-------------------1--11554445274-9355666835377764645634--11-12------AC876A5DBBBDAAADB-BCCDC9BEACBAAECDED8AA9661158C878889887887789976BBBB2-744465545666----11111-11131145433435-2222222322222-1--158333336574444626872-111311-12557455554457B33696756662222---333--22--------213----1---2-2-----12--11---44563656863F61 --22AEI-B644567KHSMQNOIQLQTDDCCDC789CDCCCECBCBGDDIQTZVQPNHGFEE88B555173487A674B6778879678FGCHGG9887579AC9B-ALDoGNFOJOJCLLLKHNaMXGp*K2MJaDFIMNDETECIHGFSEAYLEEIEANjCKVKEL7CcDBHG7DF8*888EGcYiwMfJ66NLOP8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.30 Supersandwich
[ 184] 33111243344444651355553376664457221111111122322333445133233224553133 4485934766734374444-46335844444466666DNO49894658322489944522979669BB7863333333433572233256553544521476764355733333333333333333244223343555662234555545543333333333443466542322222332238985533386B8888877767678777B99997787886754666666674444544544444444444552225621132882264342433423444433344333333333333444444444444443333333343735455554454454566443545424845235633445743557333453676675555564D875443333378787787778-65B44D468643977586B96A78685665585555769333333334443456533333333333333333333333333333467B7377786B8999A8666788AD66675689B7A8723776D65677A95A5455344445454555544364574835445444554286956785455556B55444443333343433333334444533875864A777666666667666666766662-3855522222264646556666666666-6667766676666666667AB955555867688888887876865656566416666666466662236555558989765674344553555444456666657665A58888888A9BBAA68885555555554455755554555565555555555444433443322331111111141311111-111-111---111111---34523434443644 4411666-F54245679BB9EEAEDFD7666666657877777666A998EEDE8AA9AAAA7786774976768884887677866878E8988D8888A47DBE-4CA9BEBFGAB8AA888CA9N7T*B-E9D8787B78C888958989D6A9A946979657L7BL43765C88*888ABIGUUAFI89DQACB ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.58 Aminoacid dehydrogenase-like, N-terminal domain
[ 185] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------*******zjlp*****x*****6***v*vo*t***g*woi*xZ*w*tq*MdOb**CBGBBGABz*------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.77 DEATH domain
[ 186] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----mlL-----HFK45776666665666566666557666666766666657566666666755666445244466466534555888EME5JGIEEGEAGCYZa2W7R*********yu*****x*****P***t**u****tl**sn*wo******QbmoeYTK*WX*LnfQ1-----------1-6----13333 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.87 DBL homology domain (DH-domain)
[ 187] 335122988889AA9A24535334522334621111111111122-2-12453123224435441--- 55A8E445667333D6688-AC11FF888886BCDC8FRU69696865676287F5643365R58BJEEB612223331-128331334442-42212223284734321111111111111134534534253444423111494545454124422222323246494222222222222455552211545555564536565457844545552635487644444574444444444444445A77673718713322CE546756887266675564445544444434444444444444444445664446666377-477776776652833112283-22312216318443724444314421694563333379GDF8679A9DA66676566657-CBFABFDHAG63A88ABALBAAGK6F886CA88988AAC44444444B554476522322223221122222222222222222165A82AB98ACDDCDF88888DDCG999948A9RBJHC239A76867797A5C5375423233333333357466346B48444466444143636635455556516111-------------------21399755A955555722332254422332223341-1797811111144437338887877787-8888777778878786885544334434444454444364445643344573145555555555511331111144545588622222222222222276667475854478897688787A968765454453443445955555645555456756323222222444433331111111131422223-3-53222334352233---24345313337612 5511447-E55155353554555464555565544334344445545655587B4445444422222212222333323422222233355433333333434546-8EAJBKAAGG98889D9LR9N7Y*G-IBU6698G89E969A68I76L9HCCEAKf6ED9CKEII98CB5984*45589EHJH5JDBBBA88C ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.87 CO dehydrogenase flavoprotein C-domain-like
[ 188] ----2---111-111112-----24333344321222222222442231122212232222212--11 2311611111111133333-332233333333333322531222122113313221221122132244211311145611213121332231121111111111211121111111111111111111111113234444111415555555335544454455536575343333343333311223421111111111111111111411211111231122566665281****D*Y*******4**12261123111173222241211112116657444811333333333332222223333323655114352211121111111121114222434211A6122321132225113221131221211151733711113212111112222222222311111211232115225343332221211142112112211111111121111211222222222222221222222222222221112212322332343322222225332222224623222222242242232333223232422223222225132311111111112111111212111154444412111131131121111111111112133222121412222222222222222222222111211221122255332233222322233-33332234232233333332333222322223322232222212332343411322332222322113211111222322111222222222221222222321222231232222222222224331111111111342322222323231121311211411222232211111111111122111111-111114121112111111133433443443111 5655HI91NBA466877566777777777765677777776676777778777788888777B8996869AC989DE7DD89999A8888C97A7AA998888DEI-AIIKNUQRTLHCFFGHEXTHbF**M3QMcCACDZGIQHDHEDEMCBcIIFILDOkELJMFaB5VDGCB59A6*576B8VOXd9MHABGBGD8 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * a.8 immunoglobulin/albumin-binding domain-like
[ 189] 44434475887887865588866543332433435335767675434435544278678894664-22 78E4D33333343387766-6633BB65666799A989IG8BAF56865554E9C55744BCD6C8GCEA633333336565746454777855552224557585657444444444444444663656475779AA773344568786685555333343465789854433443533335547755455577777677577777778666577668954647888777644444444444444445554422-34-5--2563321252232554454223323343333343434222222222222232222233349A88C66666666678966433365733945864464877A7A97A7A5567585583333387EAB757AACBB77776676679-78B78D687932855366BA76AA6C54587887896787777777789934A782222222222--11111111111112222458K6466556CBBABBA777888AE88885B97E8AB73455576344578BC5348653345333333344587939C898865686674CBDAABDABAADA458B44454444444444444444456557765A444655455755555755546555488412775432233365755755556566655-55555665555655555578B9754537656666666666666544455553355455554555533355554455556354533344333333333466666343339366665759565754856333333333344465555555555775555555533333364333344--------43211112-222333222222322211167676686765644 44-1434-A333236777698A7999A6666666656666566666777878C9677466665463333334465351553333335556867766878652566623B46695443444445476373Gr6-7585544544723365454483444635537433832J33645674*44465DAKG6BA58B6556 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.48 TK C-terminal domain-like
[ 190] --2---1-11111---2-----1-1----1--113212222214322544566--------11-1--- 1--11--111111112244-421172444444723225431133-2-11--2115112--321---3132322222333-2-2111342221-111---11----1------------------2411221221211143---152B653442211------54219433---------------1111211133333353133344321111133411111-133333311--------------------77437842659551177222332556222111142222222222222111111111111131133211112-115666668665637655343A32122111322312221-13342211-2-3--2-----222131--222211111111111---22-15-4111--------1---142---1-111-1-----------211--121-------------------------------2---21---111111-111111122222-3114-212--11-2--131323213-311--12-------12321311412-2112-112-12132323323211551-------------11-1111--11255112-2--11-2-----111----1----1----2223------21111311111111111-111111111111111111-35311---222122222212221221111111--322222222222--11-----22325-31----------------1111111---31222212121111-3------------2--------------11---------------222--21----------344432-2231211111-43111111--1---1---2-11 8756KLG-WAB7NMOCEGIHIJGLKLJFEEEFFGHIEEHEHDEGFEECGJLNQWKIHGFDFDC9B9AA1AC7ABCGE3ADACCBBCCDCCQGEGCSCBCBCGHbXY1KMSNmtgznyUURRVYW**S*T**uA*c*KWSQhTYqYKUSOOmRS*YmZagIW*aFENLyGIzMbHC8JH9*999CCRUj*FfKBCUhVVF ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.33 Calcium ATPase, transmembrane domain M
[ 191] 11-2--2222222222-3222222322333343333333333333333435553221-1--3113-22 6584333333333445444-432245444442355545B8233353323333354332--443224733333333333245564444466664533-1246345665561111111111111125544444546433344333735665666444444444445455554444444444444554443345565555555565555558687765556584644555555443444444444444445444532223324222222222222342443222212244423334333333222223222222244444444424855577677775756744443343533A55436643345664677453464576674655697F9A6597B77756565565558-7BD78G787784988678EB8ABA86556B8BD8BD96966666666B984596833333333431123342332232232222658654CCBA9DDEFDCB8789EEBD888858CBHCDFA46789B689ADA9EEB879454476555555555489A44437567546666298A676775888866875435555555345343544554445556676748466566666667666666666762135A751221128598665888A8A9788-88788878888888888899BB7867697888888888888897887666852677777777777333433333555547676333648233325556777774656674777777676676777974343343334555655555655555555555555555544433445551111111121111112-312222211122222222235533535554553 12--445-522-44589788AB8ABA877766677766665666566578889A7776555555666646757666756666666635559995568675537879-645A8H668655564A5765A5S*8-B6B4745C5689357845838A445958747589K79G66B54663Q32335B8DH7D63375543 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.77 Isocitrate/Isopropylmalate dehydrogenase-like
[ 192] 22222221111111121211111321122322333442333343322533554321222222224121 4454754555554455455-544455555555444475444555444455565454463365547568764444444444554567446667663423355455656451111111111----465444446556555553335476554454555546555765455645555555555556553355454555555555655555546555555644455556666667556666666666666665555543344443434444443445654443333333544755666565654443444444444544444444545356777667776787446666755354885466454554453364467659655576666845585555557566666666666-66566666786578896686666666775767868845655555555566846A62223333322223333333333333222247797546664566677597985586AAAB5867A4655444464454446574454754446555555556A855658B5458765788847776767AA666666656656666666667666666666876557776568687A6555567655556545555233766533133366775656666666566-6666666666666666667666667787788778777787887655566666366657665667633464444446668585A4444444444444465558546675967787886789997778864545755456669666668898855666666665555446444444421222222235----2-343323232243227433355655544546675 4423556-E65244445264665748644443444445554544446344454634435444444444344444444244444444446454534644444639CB16A9A9GE97A5577676FG6L6Lq8197A6656B46A86635475492E66ABDE4E655B9AC685H7887*44457AAEJ47776B8896 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * b.49 Domain of alpha and beta subunits of F1 ATP synthase-like
[ 193] -------------------------------------------------------------------- 25A1A11111212135622-26--32333333444596BA375D61-2311324212722456-A67DFA32111231----4356444335-4242--2422464322---------------1121212223111111---423433216112245465523214436-5-----4----11111---613232344332533462525447327111321111122242532343213333323211213------2--143221--1221-32332222222221112221221222222222232222222223122341583333343945265423212221142222333422-33333343-123-96686DB6H8AHDHCAECEBACBC9BBBCB99G-GDGEGRHGJEC4CCBGDDDFBFJFBC535CDFDFCBADA999999998DCA786611--------113244234222322----3888748967FDABFAEG7776FFDF88887AALE9BBB35GDF99DD9DA9A8688D587ACA4644444787FCBD75685663849B9565885655A7776E678442242222332332324234332576FI7676978769BBBBCABA9AA8AB988A1-66977-1-111AD8B9CA8LJA8C7H991N9AC9GHADDLED99999BBEAA999BGGABFEBECBEIGFBEG9C8AABAL1CDCDCCDBBI9911A7665656666A8B6354546447434656487BC8B776989BBFEABAC8AA8A8GFA5333333337DDDB67587HB889ECHAD9CCACD88732A63322221111111122--------------------------312332322211-- ----761-----11121--122-2122221111222-------2111-55-14111111-------------------------------2117241111-1121211C7K73534989A97A7HC7D6OVB-AAB5949CA8M7B7858A867A41B8332-3443HCD46A11--11----61EHTd-GV-98312- -113-1---1---1---111-2----111211111332231111111-1--11---11-11-1111211--1----11---1-11---111--1--11---1-1-1--11--11-----1-11---1-11-11----1-111-1111---1-1-11111--1213--11--1--1 * d.2 Lysozyme-like
[ 194] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 543346H-G553AAF99AA98967857998A885666656575687A88CB99B8BCCDFFE845786448854679699754555A9AMdN9UbOAAA79EBURX3CeQo*****rgZu*d*k**c*e***5***Zur**cp*rUqjhPxaT*kqpkxUfQ*casRvOgULTcL-FCG*EDB8EFIMZESAinGDECI --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-4-- * a.21 HMG-box
[ 195] 33223454555555544223222243334353222222222222232233333255554555556122 5554644444444443444-44444444444444444444455444444444445444445544444555543444444444544444656646554-144444444544444444444444454444444444455544444655644445544444444444456544444444444444555556654448888868888888876666558874448455444444564444444444444435445444344444444444444444444444444434444444444444444444444444444444444444445666755555556566655566685545556544557456554556565454445544444444455444454445555555555514444544445445555555555554455555455554454444444444444455444444444444443444544444444444455634444566666666777666677776576766664466644555544455446444464444444444544444544454445665444444444466664544444444444444444444444444444555555555555555555555555555555414455544444475665546555666656-55655555555656666655765544444444444444444446555444444644444444444335544444676645745444444444444444444344444445656557575555455454444444445556555555565554455555444444444444444444444444455554444-444444344444444444466666666664544 6634764-G556665456635555554554545766443444455565558798665555555554544563555662665555554444945553444554388838N7DBMA9CE8998AAAGG8J8g*C1JDP8BA9F89DA8A8A6B9AGCCA986BG78776A78758697888v99967A7CA7ABA8A8779 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.67 RRF/tRNA synthetase additional domain-like
[ 196] 112-2322222222222234433122211122--2112111111111122111121233311112--1 2562923355522333322-2222342222214444365525244242322234422211433352589A7222223233B5333322222312222-12455684462111111111111112633334433447778922273A58788746443334334634A9962322222422223431133325455555555555555536333355544454332222224522222222222222222222324244232224433443233323322223222322333333333333444333333333333221333224343333334435344333333734216451255211543311122234526633433333438784444545444444444446-77567565965374448765676656545677666667611111111333114445544444433444444444444444435435655256655988888555556666787657A675767338874555597658565754647522222224545564943467455555444434434845545A5363443344443423222222223233555556676554987777787777797797765-6565633133367455667778788687-77788888987887777796665566776767777777777676777777753455555555555444633333575575865333564333334445222222233355999998788666656675444454444444544444656647877777555555544534454553333433374511111-211122111111222311144444444441743 4422B99-G64-786555555545545555555555555545555545455555455555554442222421444222222555454447B45647444432487D-8D6QNXFERB9BA8BE9MR8QD**E-MDT9A88G9DEC8CA76D79H9C8AGCFIIFDB9U9DGFKEC57A8*6768AMIWQ5QB9B7757A -------1--------1--1---------------1------------------------------------------------------------------------------------------------------------------1-1-------1---------1---- * d.43 EF-Ts domain-like
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jHPIMJHA9HCAJBHJAS8j*E2LPU6HC6n9CJD7A9A8H86KBFACDBNS8ECECMECAIFGC8898*98888JEbP8F989BC99B --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.44 Elongation factor/aminomethyltransferase common domain
[ 198] --------111111--333331--1--2--11------------------1--1-------------- 342--------------22-2-----21222-----------------------------------------------------1---22---------13-225-2-1-----------------1-1-1-11-11111-----524232211-------2--113443--------------------1--------------------------21--------------------------------------------------------------------------------------------------------1--1---------1-------------1------11---2-----------17336-----112222222222211-11111112-11211312121-22232222222121343111111111122222222-4553---1111111111--111111111111111-1-3224---------------------222222-1----------121212111211112222------------221-2-11----------223---21-----1-1----------------------------12-314212--1----3------1----1---11--1---------2---------------------------------111--21---------------------------1--------------1-1---11111-2-1--------------------------72222111-2111121112--1-11-----------------14--------------1---1111--------4------------------1------------------3211 DF66KA5-C112**BJPPHB9AAHEFC777666AAA7777787656cOIQMPOQJIPRIKKIqJ98656RF5G99LB4GCBGGGNI85D**zPIUtCACMF*BSg*-6F4JJGDA8JCCDKSD9OJAUDj*M2OCP7CDGTEC*PADDFAQB8*DMFCOBI6YFNthF115aQGD4BP3b77649****I*i7C**p*7 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.50 Acid proteases
[ 199] -----------111-122-----1111112112121--4222122211213311-------1--1-24 2282422222222233323-22222422222223333344122223111112223112--3222335353211111114123---1--1121-411---2333312224--------------111111211232222221112-5223332333343333333242245333433333433333-----111444444443444444421111444112333222222233122222222222222222325411331132346114421222244422233333232222222222223333333333332442223333-211433333334332311122221121231311211-1---111---22514655522222223232222222222222222222-33222322222-2222222432333233322222222221111111112211331--------11-------------------2446421211122222222222223322222222222222222332222222222222232223222222222222222221133215222222212222243244323211111111111211111112211211223323525425544533454444444434--211-1------22232222222222122-2222222222222222222223222222222222222222222222222222-222222222222---2-----22221221322222311111111222222121113322222222222232323---------23333222223332222222222222111211522222211111111312-----------------11-----------11111-321 BC77DDG-kIP2EEGBCCBABBBBCCAAAAA9A9A89BAABAAAAABAAAAAAAAAAAACAAB9B868576896899789866777A99EMDCEECDDDCBE9EEH2B*KkPOLKQPFDMGIHFVaH*J**f1VTwPGEGMEHNHDIFHKLJHQFLHGKKSTHEIHJMDIVJMIE7VUU*OQPMLfNcrCYOTZPKLIm --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.62 Cyclophilin-like
[ 200] 22222233333333332333333244444262222222222223433322333245443452323122 3583944455545369944-47336A44444677775576442443544445867438226553748898322222222243522222555515332--2424353433222222222222224332232223334554422254345444333222222223426445422222222222244333333334777777774777777654454778456574433333396333333333333333333334344344333333334423234344422332333333333333333333333333333333333333333243266667687464473355553232243433A9452333442222332723222422222224332222233233443443448-333332448G32A996668897874233339A55556762222222222232232222222332222222222222222222225335323333377787754444885965665688825332233223222333346242232263222222222222344435454234333354534354465557343221222222222222222222222222333634666455333344644436365356112322211111153533634444444444-44444444444444444444543343534333333333333335444333332656566545666111422222333322775333222222213222544463322222556557544766625442222222223222222222333224554544444333322243322332222222222212222-222222222222222222224322252222322 765589A-O96488ACBA9CBB9CDCCCC99899989A99899A98ABABAAED98AA9888899777698689977677799989688AHBBABCBCCAAB7EEH38HCXFFBDEEAAAA999FE9KBH*91CCH8BAAD99DB89BA9A78JA8898ALK9C9FACDFLBAFB8AA9*A8989IEJN9HG79GADCC ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.127 Creatinase/aminopeptidase
[ 201] 55343443444444433555555545555545555555555555567656666666645355436-55 3644744444444444444-4444444444445444444445544543444454444422446544444644444454337854444466665623133362666458622222222222222255555555555666774447444437744444454444454444444444444444445555544355766666776566777656997777665565356777667536666666676666766544733244252215644443344437665554444554444454444443333353333323544444444448456555555565644665444654335556455555562575554315555544544444674666646464644444444445-5555555565524444454444566745754444444544444444454445444333333441133323323333233233333544545455565666556666556866666665855555555566555555555575566679455555555555535755564455444354455546566667766424444444322422222225444488A9886675787899999899999887797711375554234449877897AAACACCCAA-AA9ABBCABAABAAB9BBA7787777898999899999999998877888A527777777787772227222223333656567576464555433365555555555756666666666666855661121322167AAD9999999B885555555555555544554444441112121222211111-122121111114221111145544555555553 --11333-31-12243332333334233333333333333333334433435443333333333333323443335434433333333335336355443254777-5C333433322222322222223H3-2341211311221222121122111411--232-111212525887*888A8EELJ3HA8BC9779 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.73 Carbamate kinase-like
[ 202] ------------------------22222222222--------4442222222--------111--22 4442544444433344444-4444444444444444228446554444444444446444434444474433333333433444434344441411222442444334411111111111111122222222242666663333466666666666666666666488A64646444646644424422422222222222222222222222222222222442222222222222222222222222222222222212222211222222222222222222222222222222222222222222222222222222222222222222222222222222222432142444424422222222122244544944444466465444444444444444444148448464446284446666666644444224222222244444444444444662221111111222222222222222222224366444444222222111112233111112223242444211612444445316664222222222222434646366543353443333443646444444445863433344443333333333333333442222422244621111133111111111112-2442422222231112113333333333-33333333333333333333331211333333333333333334333333312411111111111221244444333344444222242222-2222244444244444222224344244442433444444444644422222222222443333333344442242222222444444441-211-11-221222122221121211112122212124422 EA7689D-cDG6889666677677867998999777875767799976777777678579999A9A895899989A9689997999877BH96A9CE898897IGJ2CICOMWMMPHFFE9FKDTPBSFc*H-KJRAGEEVDGQIAEEDCLBBPDHFGI9FMDCB9BSHLGCAJBCJJD*EHDDDbZg*6kPEDB9DAI --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1- * b.4 HSP40/DnaJ peptide-binding domain
[ 203] 11213112232311212122122352232312222444555552324722352D23323331-12223 2353333333333233333-34334433333244444466343453232443344333223333435744322222221222331422555515331112533343434111111111111114422222233233663633332565455422334233444524757322222222322345433332345556566665666666345545666466545466666677344444444444444544544222452222333223332322345644442225225335553535345555444444545223332224132335555555454253355555144423331222321232222114443144442222225487753344454444444434441669678675A32855577779746543333233244233444444443555556322222222222232332333323312222233452355355555555756655697777465687B8A3476666555766594667324342111111125733538471253143444243434445555554333322213333322222222222142155444323236454455547455555444534321521322122245444444454444354-544444455544454455455544443444444444445444464433334334444444444443323333334655355362222222222222224443444222546666777636665366612222322222113222224433355555555553333222333223311111111214----1-111121111111111111112222322322422 7566775-XCE6558IHMCNDGCHGEMED7BDFBDC5B9A8BAFDCGBFJPDOHILGJFDCD97999777946888A2986888786786F7HB7B5896762BDD46NA9BEAC956676694DI6K4HnD-87B2655D659537324732C57576773C8566O46M7A877BA6*88865SJOYHOCHCCBCB6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.17 Transmembrane helix hairpin
[ 204] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1123ADA-iLG1K8S11NIJFHHB2CEKLFF9DFHHAEFIBFELGQdo34FK7HGDHv7F35B686792EA9665AC8C9876B73D9AX*t1LPaGFF*8*GYi*2De3aVYRM*KGKJILWSsaGbG**Y6aUgNKKEXGP*NLLOHLTDLfKMJi*HOT*****C8SZBNOC25IF*D8FC8****M*S88R***6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.40 Retrovirus zinc finger-like domains
[ 205] 22222223333333332222222242243434222111111136222433755111122222222122 2224444444444444444-444445444444444444544878424422224444442244444444444222222222432222222222222222222222222425565555446555562222222222244444222236444444444444444344456464444444444444222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222332633322234222222222622242222245D7A66544444222222222222446646226A226222868882AA4422222452354222222222234422224222222222222222222222222222222422522222264666642222442344444544A24422288223222242423222222444222222222225222222222224222222222222244444464222222222222222222222222222222222222252222222222222222222222222222222222222222222222422-2222222222222222222222222222222222222222222222222222222222222222222222222222225222222222222222222222224222224222222222222222222222222222222224444424244222222222222222222222222222222222222121-------11-----21-----22222222222422 BC99GIAAcEE9BBAABABAAAAAA9AAABA9AAAAAAAACABABAAAAAAAAAAABAAAAAAAAAAA7BA7AAABA6CAAAAAAA9AAAGABAACAAAAA9ABFI79IHPGODCFDCCCBEGBGPDd9n*Q2JKRD8CESDCOCACDBDEBEKBEHCCFOKAEBDAKABN9EJEFFEE*GEECEaQifAWMCCBCDBH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.129 GroEL equatorial domain-like
[ 206] -----1------------------1--2-1-------------72126---------1----12--1- 6EG2J11211111116411-161142111112567682212HDET4413662533221118762G73hfTE211112221264211--111--2------1---23122222222222222222---111-322-FFFCD---M3745E98612331111115455979A---1111111-111322--2234666665563656555444445566365642133322273222222222222222222221111111111111111111111111111111111111111111111111111111111111111111111332443333333432442222223271232433224344442433421136-3----------22-----1---1------------3121-3-2-11-1112-1-1----33-1-1422232122111111111----5---------------------------------12---1112------3------221-------22322--11154533765372345234221---------14771D714234-85112156346263333536S16-------------1-1---1--122121123252-212-----1331--1--43-33---4121-------21---21111111231-1111-11112111111111-1111-1------------1-1--11111111---11121111221---2---------31913-------1-1111--------11213455553234422216422----------422211111-1122114353433311111124PQ9BFD--------12-----1-112-111---11111111122-1111111143- CDCEHFG-mHD677C68998AAB9998777787777788889877777898898677A77778887773888888885887888887776AC8BDB8887776DFN-B*DRUZQSUMJKGGKKHYSGYJ**R6ZNmCGHHSHJPEGJKGGJGDQINKJJAG9HIFBAOCGMFFHB7YcF*GGGTOo***9*xNOWYUSa --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * d.219 PP2C-like
[ 207] ------------------------21111111332------------------3-------111---- 6656655555555555555-55556455555556565566566765575555555555555555555556555555555555555555666656664--5787677867444444444444446666666666666666611187566677656555555556667666655555555555596566555855557575775576556655555756555A6665555556555555555555555565565555655675656666556557655555556555666666666666666666666666666666666666559967666666666665665776566556556577655668556665656552555655555555555555566655555555555-65555555555565555555655555566556565555555555555555556555511111122555555555555555545556656588788666666666666666666656666888867886787778777977776666676676666797667666665555555555555554567666666565555555555555555555555555666666668666666666666666666666665-5666625-54566666666666666666-666666666666666666666666666666566666666665666666666656666666666665556555556666666756666666665566666666667666666666666666666666688887888866666666666666666666666666666556566666644454444551--1-1---1--------1-------58555555556769 11--111-211-2223322244344443353334333323332221432233433343332222222222222223313222222222213232222222222223-121211111211--11-1-11-3D2-111---11113--11-----11-11223112111121-33321136I42333A35626B214222- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.59 MurD-like peptide ligases, peptide-binding domain
[ 208] -------------------------------------------------------------------- 433-4--111----4--11-1---13222221----1621111241--13329963AA--11524-6545111114211---212757777738661--6HG894FC663333333444444441123342222544474--186233-224222233333122-134212733222622339AD4411-F9O8888868A8888A888DPPET88ACIGID29DAAAAB9GC899999799999998777BL163652C111BCCC548D757888A2431---43422222222222111111111111132224422216LK718A8998837353889222E8H-1D649AFHQAF2X83ABBB6-1-4414552-11112224311111111----------1-11211212331-332333544344-11-21121-11225--------1----423------------1----1----1-------11212344445444444333344334444445435445--544234334321424483656644455555541442367547332O433339898AB8795535E9B81222111111111111111112224778756767579D78888B8688986865866--19646------64665566666666666-6666666666666556556559452246656666666646466565666653-455565555666--2666565777746658333545322122224BBBBBCBAAB3566664554655445656-111111114B8C988888A9888554444434411113-1822----6666666677--------------------------21424212324934 ----743---1-26AA978lHQGHJFT652222enHH66656621139HcJeVZIHCS7F9B--2-----------------1--1---A7897633323--39LB-2323685834433135486372DT5-748412541485252155247253661-133131I3335J331DK48556X4TEAR6DM-154452 --------------1--------------------------------------------------------2--1-2---------------------------------------2-----------------222-----------1-------------------------- * d.7 LysM domain
[ 209] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 212298O-9347GFICEDEEDEDDDEDDDEDDEEEECDDEBEEDDDADDDDEGECCECCDDDEDDECE8DGDEDDEFAEFDGDEDFCDEEJCEFDHC9CCCIERTQ1hVI***x**zggbYfoe**Z*b***7***RlgZ*XjtfXlgcStfR*fvnglScaMYTIGOIMUDGcL1564F7684496DEE9658****G ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.189 PX domain
[ 210] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- UKDGJJJ-*OO5FFNB8BCACFDFABCBCBDCCCDACCBC9CCBDEJCBFDACC6A9CCB9ABAA887488A8A9A96998ABAA9B9AIKG8PIOGCFA88BLUP7TwCjovjy**iRNQVoU**W*U**wG*x*SQQRnPcojOfgQPcVQ*WedljGLLPaVJGYDMeStOD9MQGoJKGYDq***F*pGFaeXhG --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * g.66 CCCH zinc finger
[ 211] 33142345545555552232222464466557353333444445345353444422222222222344 3355A44755554578A88-8B33AG888886GDEE7ACC5CA975444444875646227893B59AA8444444442444822322223313--1--1212344533222222222222223332333223235555532245433733445553335534435545433333333333343322432543333332333344334443333333344533544444444333333333333333433333232442522244444433233222233322224443333333333322222222222223333333333363553333333435423333334374434336667595465744332125245553444443587833364463555555555571896887875B848887887888A979333687777787A3333333363335357333333333322222222222222222225344534554478878765565777966665678533532233465444457447443352464222222222435432444233343333132322223333336743222222222222222222222222322332233323344544434433333334345112445611-11145222324443433344-44544334444344444434442222233333333333333335444444432222222222222111222222665633675222222111-11222444644433373BBBBCBA9CBDBA66773333333334233322222232223344444766222233334444441111111121-----1-111111111111111111133233232223342 3311559-725133554555785B7B766555576665554555456547666777556666433333233333343-333333334436F5465A5443454788-3G5MHWCMKF78B8797B779AU*D-98C7A89H88D658687A66ACB89CGOVAFB49IBBIAFL53766*44457H8CN5C856A775A --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.128 Glutamine synthetase/guanido kinase
[ 212] 44-1-473445334334746577864453453------------1---11344--------1554-33 55B5724445423256777-B43336777773444444654665364243334456441143544345A52--------24444322111111211---24222223231-1-1--111111116645674565623333---63222622211332221112325444112211112111144444---3344444443445454444344345544454334------4532222222222222222221-------1---11-1------------------------------------------------------------1111111-1--------------8--63GE2454--83-------3917559232239EGEHA48CAB8C77777777777189C89DAI6842666668688776AB46577EB8CC76955555555C8824C69443444443433334434433344344444478517666EDAABAAC9998CCFKBBBB5CAGH99BB77BDA88789BEBFB797A9164C845555453339AC3A9976867796662D9D8G6B2389796455745554444443533333334922489994876A9568CEGFF5BHGHGEEEDDEFD--24B96------C8A9EB3DDDDDDDCDD-DDDEDCDDBCDCCDDDDDA9C988769FDFEFFFFFFFDFCECBCBCBBBB32888888888888222722222555577566333334333333224555553464797AABA888967878A6664434355445888B99999A898777666666664444235-222222----------------------------------------------2422 -3--123-1---1133321223222145444443443444444344232433333332222233543313211222622233222312223232241242211313-3332223252-111132321916E7-325211-411211111-11131211321156143511*-2513-21-11212135I132224121- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.21 Heme-binding four-helical bundle
[ 213] 22122243333333333233333265556554112111111111226232587111111113333123 21312---------25422-22113322222242331143344221---11212411---113111331-2----1111111522222112311--1---2-1121433--------------15413342334355544111355536444333311111123225475------------3224422-135334333443445434124435443333-1--------1-11111111111111-1--12-11122111113311221-1-11------------------------------------------1----1--1222222211211-441----12--514-6223-31213211111--122422C1222243C577963323322222221227-4C5487943821244255A465352211132633332223333333334432322------------1111116131111--11131281111-174434583555754655554423D443---6412422213233131333-11--------11341149541458143556-525546334234234661---1---------------21113332211231122321111111111121111211--41121--11122332212222222222-222222222222222222244422--13332333333333323222222222-222222222222112211111224351231---------------------1---5311111111151212111-11111111122121111111111--1111111111111132222222---1-1111-1111----------------------111111111113-1 GD67TQ9-W9A3BCH6877988688886666665556756666666667A778L577677677549435546323554559444547A6GME8GIH66654A8E8A28wKeSgRUYJKJJNLUNiVGaK**S3dOhKLJFZIMVMENJIEPGEZHWPMSGJDOoNKRQLYcLSXC4GHK*LNJAGejx*6srIDGDCAS -----1-----------------11------------------------------------------------------------------------------------------------------------------------------------------------------ * b.15 HSP20-like chaperones
[ 214] -------------------------------------------------------------------- --------------------------------------2-------------------------------------------------------------111111-----------------------------11111------------------------------------------111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111111111111111111111111--111-111111111-111----21----------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------11---------------------------------1------------111111111----1------------------------------------------------------------------------------------ 5211BCL-H74-43821222222231222222222212222222222222222222222222212222-21112211111122211-1133313333333232863-LB6y******pongrvp**k*l***D***frpm*jw*pdvpoY*hd*q*xysWj*gbVeT*NWnWqbM1547K68665D77B2A72389883 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.11 Acyl-CoA binding protein-like
[ 215] 22663287777777764666666666654756777989999997877766777A66677475554-44 5674664444444445544-45446844444476664565486764554444444544334544466544433333334545565554444435551--4544564444---------------5555554555645544666488655555556665655576445556555555655555333445424344444443334343334444443433333433333333453333333333333333333343-33333-3-3333333333333333333333333333333333333333333333333333333333355645555455554554444444635334456755555353674465733564444533333586574455654533333333334-54546556334343343334343476455445555534455555555555444454454444444---------------333344445455445555555555545568555545577558745444674355757655576644454444444555566566576566666665676666656666656566556666665616111111176656556645545444666666566666666666654-346451--11166556646666666666-66666666666664666666675466666666666666666666666666644655555555555--444444455555565466666635545544544444444446455555554555555545433333333644464444444444554444444444444465444444--------4---------------------------31333333335654 11--444-311-33333333333333333333333333332333323333333333333333333333133333333-3333333333336333343333333333-4418554659344346484674Cd6257H3635644612454553274656658859415C67A64454344Z5434453773464484544 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.139 PurM C-terminal domain-like
[ 216] 22424222222222222222222422222222222222422223222222222266666644224-24 4864444455544444444-444444444444644446444444644444444444461152D4449544464444444496544444444444332113634666526--------------2444444444644442422264444444644445554454444444444444444444464444443446CCCCCDFA9BCDCBC645568DCA44486454555448A3555555556555566654466655556555666655757445877555344447444444444444444444444444464444444444654A5555555555484444444646445454664464444555A4636243988844335446574444666444444444449-44444646565478866767787774342745444464C44444444446446622212222211---------------111146656857754H8888GA677788EG77774888D6666444464674494A9B644444447744444444444553884645496444446464444446646454646A646666653633333334664444875464474466444486A44464468666315322343144498A69748778887877-7787998787777777775777AA44497999899999999997666868543666668666666133533333444444767553535333243225888886646444555557575575564554333333332686944444448444444444222222222454444443333333352--------12-1------121-----46755262222424 11--112-311111222212222212522222222222221223222246284822222222223222224122222-2222222222322222222222321364-29151342432223323432225A2-3221223212211231323222131712318211111611312222H22222644A2442264332 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * c.78 ATC-like
[ 217] 332221434444444522321212-2223123------------2-1E12322--3-2341334--42 6893a11111111135455-5433455455534647316365133814-542638527--ED51M6AFBG1---------3132-1--1122-2-----1522253553---------------1--1---116147789-1-F3374222911----11-232-69879----1--4----M7A24--13264444475537447675999775753235854-----1941--1111111---11------121231---11---22----1--1-33342233--222211132312222222222222133--1121234149121241281735223675C32-1633521-2314441432325352-42111-----3233312233233------------422-13-233--11121-253132442114231111112111111111---2--1------------------------------2322-2211-7555686766533269888285423333--334413--2321-21232---4---1111123431-G14------111---1321535-11332AG-41--2-112----------------1--21-3237233-D5574933B992C74623C--32111-------2-11-1--------1-------1---1------------22132-----1--1-------3---------3-------------2D-----11112-511111-1-3----1-1-232221----112342435-2222313221--------1-112111113311156EBGBACCF3333--1-11---------------------4--1-6-113-1--111133-221-1----2-4 3213II8-612235CILJC7AB7CF8ABB9ABCILJNKKKLMM999GEPqWVaZNLVQDABCG44334145445434244455555444EfKLE7D33333I5GRO29bQqJDEIEDA9A8BBJGHBIDT*I1MHS7BBCECBC77ACB9BB8ECGBBC5BEHL8AAH66P8CI6-FT6T222OGLuj*Gu*F7DG9BL -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * c.41 Subtilisin-like
[ 218] 11-2-32322222222-23333314222112111111111112111111232112222222112--22 45B5622222222242222-2222442222242222589A48A6524222226774232244A262576433---3333556554555557526551--47669968442222222122222236656566757676644333637776775456666666654557754667666666666555332247354444444444444446644464443545343333333573333333333333333444442-4443313166333322151344433343233554444444444433333333333333455544443342A94444444-4-43334442224133613355333421324443133637655811111655775575646766666565665155A66C57464334444446444568454516232324544444444444458642232222222--3433333333332--11235545443455666756A8996657AAAA4867658682666867456564574556844465464555443466554245222335443211131112255556834443444444445245444445445522777799B4875999997BA99989B8A8984-3765631----85666766666666666-6666666666666666666779775755555555555555555866666665255555555555522574444444446678955555555555444544444446567777777876765768777222222222555565555585755555555544455554441444444--------111-------------------------22123333332743 21--551-633-66455562545565544444444454442444425344455533554444555355353355533-335555555555D556264444545566-664C5A67684342272762926J6-5273222523632213263354546534226242757B23737452Y2334577885B552A9552 -------------------3-----------------------------------------------------------------------------------------------------2----------------------------------------------------- * d.96 T-fold
[ 219] ---------------------------------------------1---------------------- 453262222223225AAAA-AA55E9AAAAACBDED9A99255744523333455435227593977899322222221111223233434413332--56666324143333333333333342212222223255544---6156666652333333222334477732222222222223333322213222222222222222211113122211112321111112121111111111111-11111131222212341111211111211111111111111111111111111111111111111111111111112123222222222212222222322111422211211111113221233614244311111322222123333333333333333-544444543431522255455543223445442333445333333333222344211111111112222222222222221111133251222245444453233333563333344555565225553553334667333732333222322222324664D7832331123331555444354BBABED26434122222-212111111142112446556956684488888586888888678662-34232------65444544555443444-4444444444545344445666544444444444444444443644444442244444443444411285455544444A9582222522222223335466557455558888899AB66674877433333333355577777778888776666645522221121BB66662222222222311111-111111111111111111112121111113234 5555789-P8766885776554564566655454546778557546554545555674554555545444454454535544445543359878778667695GDE3BQAJEJFDFI78547E7NH4L6**I2EDS4764E6CFD59A86F65HAABECFF89FA67DD8RAEE8AB96k65599PPMS5OO8AHCDB8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.112 Glycerol-3-phosphate (1)-acyltransferase
[ 220] 11121233233333322223222255544544112111111111113122222111121113222-22 5443D33455433325566-6411B36666654666833349973443444442254222542296KFEJ31111111112152222222222222111233338434311111111111111233333333333444661118364654443333333333344455753333333333333333311365422222222222222322334422222354433333332423332333333333332233312133142-24423331213343332222111111111111111111111111111111133111222211112-11111111121111111112112113376343432242121-21425533333333577975557777733333333333-77777577353333335573333335333553555553355555555555455772222222222111111111111111222233323444445566665557756665599825556555523333444444554444444444744454444334444422222222222222222222222223269222222222222222222222222222332232222222222222222222222222221-254641--11124222222222222222-222222222222222222222222242222222222222222222222222222222222222221222222223333322222222222222222222222222222522222223222222422222222222222222222224222233333333332222224222222211111111112-------------------------11111212224343 2222IK6-C541566AABIICMITTUO7766559E889697A9766B8CGIG9C77KBA777555444354355544444455556555EpLADDQ756769699A14KCC8A76756555666795J7T*81BAC67686657467785664B557C7344676AA578s33567779*88887Imh*Av*9A4444A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.128 Terpenoid synthases
[ 221] 223122111111111121232443344514431-1323212132175B75F92-33334531111-13 --1-6EC8DDFG8E21311--311241----132227G79263668759B74D8465B44781ALC75BW81111111222332-122433313332---11111322-3333323333333332423322232447766224D184455523322322322642498222222222322228553333-39AHHJHJEFHAIFHHIFFDEDDEHIH888FB87777777LL7CCCCCCCDCCCCCC97799812122131115512224111314446665555344666666666665555555555555555333555435C57BBBBACB6D8453338676628492214IG41142334433328542221116646633211347765875555555555E-433334447333CFFA896AD9B88612157OD9EE653333333332443118711111111--1111111111111-11111-11112433345666865666655646666567441112--1112221182422311411-1733333333--2242-7833313435332-212211145222251452366144443111111111132211447A62721122123552324322523455331-3244311-111O7AC5EC8AAF8DFF86-98A6EAF6C89GC888886FFGHHAA99899999999999999E88C999A61DDEDDDDCDDDD115-----------2CAH8886A6334555338334432215762684668588674437991111111114CAAA99999FBF7711------------111322------------8332224------------------AAB32322333331131 -------------------------------------------------------------------------------------------------------------------------------2-----------------------------------1------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.22 ABC transporter involved in vitamin B12 uptake, BtuC
[ 222] 1112-13333333333-434222244433333222222222222222223332212111114442-33 4454654566744444433-343336333333444546AB33436564444586854511868674875432333344112272322244452533-1256454544541-1-11-1111111122233322233444332226333333333333333333333443433333333333336543333124588888888678889875555588734563333333337344444444444444443334122344322224433442324322222222-11322122112211212222222222222322432222233145222222222222442221232335222344423144234443232533555534335248443334433366676665656-55755745G943A887898A8A787B44445864595563333333365543345222333332211111111111111122123235423443697777966666557899988679A596A246663363475B6684433222534544444333444435253452545543333333344554545274375355554533333333333223336644334545466666466544666756773-3334322122274875554444444444-44447444544444444456967766655555555555555557444444443655555555555223522222444433546444444444444444667764635583AAAA9AA9579775997322222222365575555556656555555555533332222553333---1-1113-1----1---1--------11------33333352333326 12--764-3-1-33425756444788633334333343333333334335497BA744544433433334336343323335344334549655563333456444-47383B4356666643544665Gh7-9482335444634447746844B737AA46A446833B35863444i44433MDDF4A43285646 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.127 L-aspartase-like
[ 223] 233-2233444444443344433--42-13--111--------1333121111-23365521232--- 4664313333333289699-9766C9999999AABA8GJJ4746454155435474541131C553D999654444444255413123123424231--1313383622-------1111111268777655435344443332-2121--1-2--112211-2-2---2121--1-2111-66322224-33111112131232225243334223352243333222336-222222222222223222331-2221-111-13343-11131222--------11-------------111----11---1--------2556A99999B9B9D327724556532--A662B88682131725612--2127338--1--256882248645734343333335-22422234643-533A4444544523145636343375888888888244316331211111111--11111111111111111133A32233236668856544466655566368773332-233454533834755227253535-------111822-DL4334746877615472666A37766481B2--3132223----------4214233434331415333545434833352353685--43563------4253532AAAAAAAAA9-A9AAB8AAAAAAA89A99755654222545555555564545536446666--233333333333---2222221-1151234-11222-----1---33333255533277874655155543244---1-1---2466A3333347444324454433311112262551122------1-51---1--------------3-------44524314312311 2322945-G7423238BDA89A7EEKB78364487A7CAA69A5769957AEIJ775887677353631231554332345443223325AAB68785758A5A4618G5W6996966392665A96B4K*8-ABA487555755375126237565555686I798JAEGA9C56496v554778AFKB8ACB48548 -----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------11--- * c.4 Nucleotide-binding domain
[ 224] 33212323333333352222231221111-13111--------2113231533-21122112221-12 34A2722222222282344-44335G544545645456C94636A4333221525112--44625559773-3332212-1133244444443533---15-439564511111111111111146454433366222542222473345533355435334454434433333334333335444432132222222212123222222223222113211-12222225421111111111111111113-------1-1-111111-1-11------------1111111111111----------------111---12423422222222222333111131211-253244643153-231134--22655542222234BEC434A535333333333334-785674866342A88A446CA654A45665666577645444444445443534311-2122211--1111111111111----165A55454244667957446455884444447773455255453653357759745434334422222223333333C583432232333255544456533334A452444433334364666666664557563454755465422232223223222422471-15557------43754543444544354-4334444445444443444334546545555555555545455544433344164445445555511442222244445679611111111111111133333344545498A99B8A89A985979434423423222222222235344434444454523331143885577221222226311111---------------------27433333333743 ----654-311-34399A9BAA8FFC89945455555755455666GACIBHIIAA8A698745534554446576645544446445545893437566766654-6F9C7B565F8495767A78B8U*B-D9F66787787949A77878B7776A553577599AGC44B43644*3346568EC9BC735356B -----------------------2---------------------------------------------------------------------------------------------------------------------------------------------------1--- * d.160 Carbon-nitrogen hydrolase
[ 225] 33-31353556654554-66654661134344325314544443448952553343245531221--- 36938212222--167766-6C--796666639BCB659B543543323---4361-2--43734496C63--------6ZR565636---------111221242321--------------11133241223288855222463221222111111121111132222------------4424411-3-63333334323333333366263322341--111111131222222222211222211211------1---11-1-------------------------------------------------------166-11111111-1-13--122211--3E--24yr357A-78A11122--43353331111138A6783B6D6B544454443436-99C99B9F9711777667659877B9423749686774844444444944-5A241111111111111111111111111111122443-48748B8888AA8BBBCC9DBCBC6AA9CCCC9149A7696779469778645554571111111112E872CHD46AB6E666D-CB8C95949CEBB699L5AA434367151522222228E677448524346-3-366AB92BJBDC7AAED8JD1--4942111111HBA8BF4EFFEECAGDE-CEEIDCDEEEFEEBFEEE9DDD9942CEDFBDEGEEEDEHECDE978C9BA1-8656788787881112111111111535726669772324334464444423344438889967466888B6761111111112387D344449965644243442221111226-442233--------------------------------------1--111-15521 ------1-----1211112222121212222221112111111111-111131212223111111----1--111------11111---11111111111111122-1--21322121111111111127C1-12111113211111211111111213133151222111132-1111J111-1513C121--3---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.81 Formate dehydrogenase/DMSO reductase, domains 1-3
[ 226] 22----88A8898988-4394---72243232-----------11-1---2-2--------3531-34 33A3E226445212BTL55-5X11EP535558ZVYaB9ZU3EBN544333328593422298D366CBBC5---------1-922122-----1------2131323-2---------------211526222345554311134G9C7996254432324269299BF622222222222254334---2233333332443434343333333332422223------242111111111111111111------------------------------------------------------------------------1211111111111-11----1-111--2--1122---1-1---------614B775-1--188FAH6354326322222222222176557B754A7-633586B6798C5C4353C8311273677777777266653431211111111111111111121111111122V*419HC9CJGIILLEFHHFMMIMIHKK6EPEd8NF924988BG7859EE6KF5B563553211111113333CA4111--1--------33425431-4444E9-11111111111111111111111-2133322355317231111132211112132123---2513------3212-224441411134-344441144441444444365722241111111111111111144223334--232333333332---3-----332367479---------------B998A5A1426499A979794ABC967651--1-11--332231111123433436676644522222221221122------------------------------------1--1-2-21142-1 22--112-623-22855759776C9AB665645222222222255444446AFB5564544412211112112121111112222222238454343334434455-6W7NBC9CB3222314385371DL5-8571313323442232231133555A78738654A25633645GF9*BB9GJIBFK5D8774575E ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.33 ISP domain
[ 227] 55334534333333344454545365584555334332333334434626545333333333333233 4474733444533367766-67336666666567776667476656572442666745--6862768887322223442343344544443324223--353336243422222222222222533343333343555332224133433313322222222222511211222111212215553333233333434444344444444333444433344344444445344445444444444444445435155113326622554232213323333333333333333333333333333333333444433444334533444444523232222222422325222154211223123333422414555433333345444454454444444443444-7757748746525445554445444445544454444453333333343332334111121111111111111111111111113535335554666766565565665655555575455563366644555545454555353443333333343334434534344343444344464553466768843253323333333433333332434355443544457525655555555545555465--2233422122244443444444443444-444444444444444444444444344444444444444444444444444314444444444442224333334333356453334332333322233233333233435555665655755645621111211124445444444556644556555553333113422336611111111123----1-------------1-1----33333333333533 3333463-9331334378555555636443444555456555556656667687675567673343333343333442443333335444B67566444446543424K394444374435344643H4bjF-C6A3652544442454341173644565544343223111855589h87698EHBZ5N84772447 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.96 DNA-glycosylase
[ 228] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------1-------------------------x******kqnknuk**i*p***1***fmkn*omy*Woqpbrjd*q*rppDQRYeVNNjNM***K5-----------11----------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.123 Nuclear receptor ligand-binding domain
[ 229] 1112111111111111111111121111112111111-222222321311111113111221112111 3222622222221222244-4222324444423333212226531224111-113221--421122122331---211122211111122341122---1522142213---------------1111111211111111---3233342221111112111121144321111111111111111111-1247777766877886872233337752223-2211111162422222222222222333331------1--111-1------1--11---12-----1111-----------------------313----443223333333131233322223231222221322363-2423214121121211111211121112212221111111111111-12113141132-11123142212111121213212132211111111131311111111111111-------------------12121122222322232222223322222223253224412443222313544244333332222222222213524114122632223331353254554556575222212222222222223222324222223335532232233333334433433343331-12322------33462333333333333-3334333333333333333354334534433333333333333322333331-333353333363---411111221111422434222222233332222222232242323222352222222232-1--11--23333433533333322323222232222115-11------------1----------------------------111--1---1221 A999DDB-ZCC7ABA9AA8AAAAABAAAAAACA998A99BA9AA9999AAA9AAA9AAAAAAA999AA59A9999BB7CBA999A9A9AAEAA9A9BAAA9G9AB96ASKOLLDGINHHGGJDEWLHPFp*L-FGVAJEFGGEGGDEGGGELEPGGDEDAGCDFBCBB9FUCDFB9ABD*BA9BAKHOP9JDCGFDDEF ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.111 Activating enzymes of the ubiquitin-like proteins
[ 230] 44232244555555542334333563332242112121111111213251222233334342114211 144222-1----1--11----3---5------46663434112222221111533333--223-2353233-----------522111--11-2--1--2335563-24--------------------------55566111353152224442232332343133333111111111111433443313545555535555554455555345545566233------5243333333333333321125-2---------------------------1---1-------------11111111111111--111----3221--------1-11111-111121--31-1233224313431122-213113221-----223442212233244444444445-566455443B1-B44756777755532-1465767775D--------3----112-----------------------------31-4114865565595726675555477774686555451265535433457473222211153222222213133333543232212221133311122-543456441----------1111111111--111122-33-443532222222222213233123---2312------21--1221111111111-1111111121111111111554--4412222222222222222311111111-------------11--11111222211532--------------1111111114211666659575474311121--------22332444444435633322222221111--21222222----------1-------------------------11--112--111-3 46335541H65155978989779CA8A777767667887787767698789AAB778658887897883866A597669689999A478FGA88BB99A69789BA2Ac9NHMILFJJKJHEGJbSJeL**N4fKYEKHEKHHKCBHONDMKCOGHFDFCFF7FCG9D7ABDFF84EEB*9A8CCDEKH9GCEACBCA9 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.42 Arginase/deacetylase
[ 231] -------------------------------------------------------------------3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------2---------32------------33---11------------------------------------------------------------------------------------------------------------------------------1-2-------------------1------------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --NM--4--------------------------111-------------------------------------------------------------------------4*eskgruprplo*r**g*d***3*u*eumb*nt*ra*qhe*fc*d*ykdPtUiUzYgxSNdOS*O-VR--221I12-7---1-7hiZk- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.68 Kazal-type serine protease inhibitors
[ 232] -------------------------------------------------------------------- -------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ --11JLI-842-AAEABA9BBBBACB9BA7BACACBBCACCBBAABB9BABAABBBAABBBB6688673855877564558689B86894A7B8777666457JHF1R36e*****xidYUglf**f*b***C*t*ScXh*YezeShefWxTN*jqjjmHVfWLJHDRJJXDROK4244B65442EBFG9D9227A891 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.238 BAR/IMD domain-like
[ 233] -------------------------------------------------------------------- 4D8-------------------------------------4--14---31---4---1----3-----------------2-266943-----1------11---1--11111111111111121--1--------11--444--O76B5533556---76777865445-4--6254--5-945C78C*5622222222222222-22221122125452254222222-32111111111111111111211122222221232122111121111-111111111111111111111111111111111511111111155422111111131216663353-2342-43386787124932444635297*333335331345753---3-2322222-2121---15-43-2-4--5-----2---11-4356-2-11-------------33312--3-----------------------------61444-75116F9BCFJGFEEABAEEIIHIAFIKACDEJ52FGPJCE89GABDGJA6AFBEGF36HG78EB987ICC5CAD946--77423-C9FADA9LC9989F9D7255BA333333-1-------44A9855DAADFIBAHDADIJKKCHNHNLHHILRHON--3AD9D------725834868896BDC8A-9668ABG8888C8A76AA7666755554342434345343423547622341-A797AA958BA9--AC44344999869G74424473432452HI497BBA6B7D4ABGHJIEADJ8A89E99DDB875686687HFEFEDDDDECCFDLJFEGEDA99KFGF--4-214444------------------------------------4914432111-D5- -----------------1-------------------------------------------------------------------------------------------1------------------------------------------------3----2------------------------3-----3---- -------------------1---------------11------------------------------------------------------------------------------------------------------------------------------------------ * d.24 Pili subunits
[ 234] 22323122222222235555533222222322--3111111112214143333-24424241221244 4887735433354365555-53225553555533336756457848524562544245226343576644333335442112222544212312112--131313114211111111111111132222222233666772225434444411133333332221133532322222322224413333141133333344144544452221134411122111111114211111111111111111111142133112234411221221223332331111122222223222222222222222212122111222131144333333323213221111211112211521324561133333311363633311111112223222233322222222222-23222222224132223224432222121122111111122222222-11212321111111111111111111111111111133322133313333433333333344333323333334322122332433323312225222322222222224533226122231342322565555667557534363333333333322222222232354114634242234412313314111131331331-1111311-11143334333333333333-3333333333333113313333334444444444443444444533333332133333333333311121111122222332233333413333313333333332223455452542322222222444444444224454444445278222222222211112125333332111111111-111111-111111111111111111156455444444311 2211769-833255879B9ABAA8968AA8AAA89ABC9CCAB989979A899A9A98B867A97688387A747AA48A8989898A8BFD9ADBB9B8879BAB39D4SAIDHBB78878A9JI7M9c*F-GBMA676E7AF9AA664A77CA99A9GCA7GBA7IDFJ87B76687W56488CCAGA9G57A9989 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.13 HIT-like
[ 235] 1121112-111111122-11112431122331212-11111111111111111121232231--1-11 4573732222223222222-22222222222232223633622352342456594345115452824667312223443333212212446614331113523235442111111111111114111323442352222235632C644444223355554434243333555555555555635112243356787997867778B753564677833437224444447644444444644446334453532232223334422243322343224334353344111112113228766656554655455443655336557555555555554774988637245593477444334321112222414944414326537677474634533333333337-65555F558772655C545656744B4342274424252555555554B945535222222222211112211111111111113AB7624423522342462222554423233227324252356424B85A553422243428455754434252724476334374966882435635428335344364121215134212111111122233645442457244428EJ9555955738473351-3244611111137223834885494A4519348366545996244347764333394424243362556346544433438153334333363511523333366783348943454445454547474685723123256896A69399B93BAB222222222335363536552244433443333374352295444445333333333221111-----1-1-111----11---22224223222622 2112222-622-33323333343-3323333333331444444333122331323323213233333333333323323333333333338331243223343331-2E39342253543244483153CH4-4584134314523443443344744522227332333643736565X4445499GL3B95644435 --1------1-----1---------1---1----------1-11111----111-----1-----------------1------1---1--------1-1------1-1--111-21--11-1------------1-1-111111121------111-----1------------ * b.87 LexA/Signal peptidase
[ 236] -----------------------221112131--1--112111211111-1-2--1--1-1------1 113-552666625253122-28--2322222185758747233434655773A56342--2369313452222222327-123221112223-211---1523225332--------------132233322233444441115142232221211211122221244321111111111112412232-76A999998CBAB9B99DOCFDGB9B97A96D48RVVXUR963CDCCCCCDDCCCDC97898I233FO32516GE22OU2545574987C8BBABAACIGGGFGJDFEEAAAACAAAAAAAA799111A99E2738Q66678669672a33245532242455115211213212DDB23161-33222-----322222242222212221122226-46146441442-222133344121343-33134423243---------1111533------------------------------121311111364466632221AA944444247574143-2643231324333214-5212131111111124143412431213-2111--1-1111121222211112----121211-1-------131121175C212312151111122131122212412---234511-111C8462A5CCCECDBBBC-BDBCBBACDDCECCCCCCCGFIAA342F9CCBCDFDDDDEDCD8BB8BCA94-745555555545--12---------135514447441111123454334423223513433445544333522311111111119AAC888888A7AB443212222411111-1422112233313211--1------1-33221333-35332-----1--1----3322 ----11--2111351111113211-111111112111111111111111111111111111121111111111111111111111111112111111111111111-2111233232113223142162HPA-656111111274-1221224622221331-211172271113123-----263113111-132231 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.44 Phosphotyrosine protein phosphatases I-like
[ 237] 2212127777777777148373677777727766666666666666667566661111111667-166 2237A38444438388866-682288777778888888883ABA32223111333223--88B8A9A9A9811111111226622213662626661112423383413111111111111112782732222776777732432778777787776666663779777766666666666666277111384444444344444444434434444888832266666684333333333333333444431111111111111661111111111111111111111111111111111111111211116111111111277777777777777677777777721116677789772168774221661214444111116886622388888777777777772C7677677282-888888988899673329988888A896666666632226838----------111111111111111----12933333335999A999888899998888789994444243374E74488838344734348422433333334871662626666666626667666C722222626211111111111111-111122122225384336132343333643333343433A41-1247211111263336232222222222-22222222222222222227774477366666666666666664222222221932233333333221511111124262736221212111111111222222223333888877888888848881111111112233522222346441144444333222222624477771111111152111111-111111111111111111111166111112222 1111113-52211142222222222222232222222222222222222222221322222222322222222222222223342322224222293332212333116121111122111111211417I3-315111112121111111211111121211111-1114112-4446Q4444454562432333335 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.90 Tetrapyrrole methylase
[ 238] --1112111111111111------22221342-113311111-12-1--322221111221----111 13A3913233325243322-25113522222264556575241332211333546312--5561456CC8412223221212512111442514332--4638693714--------------12233243324322211221324341222-------21111--3361-2-----2----344-----3124545656848765562144328761112111222222231222222222222223332223323323333223322132333212323111122222222222222222222222222221122211122227255544562523244233353-23132--222-2-414323321-3234522211111125564232223222222222221-44533347172-53244415561173-2-22133331-11111111111113212----------111111122121111------22-23221375676743333554844442578442251155343432523271434-11332--------12333411-211212322116382434428A8856111----------3344444441--2232452324221-34444412454428456255--12111------34322463334333333-3333343333333333334677332245454555454445445645553342-444444444444--1-1112122223123411111111111111143444352443244444843334342454544334334-4333222224434455555555554444---2222222--------111----1---1--------1-------1-111-----23-4 2-11A85-H64312756896666777666764565548565666566656758966875656566555477775A665665889774443A66B9E546645567517E6KeaRSTMBBF8ELFPNAMDf*Q1NHZBEDCIDJJH9HBB9GDBTCIKJJ77889BD7C6AG6BB55783B21198QBDD8A833F9BA3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * a.111 Acid phosphatase/Vanadium-dependent haloperoxidase
[ 239] 1111111111111111111211114223323211122111111222121222211111111---1-22 1234856666666657755-56447755555667776655344754342443444344--666274655651111111-1--4213222223-2--1--11122432521111111111111112334344333455555---4287778866666434444567655654444444444443212211-323333333333334334332222333222223311111152222222222222221322321-1-11-1---11111111111-11111111111111111111111111111111211111111111111-211-1111111-1-1---1----1---1--1-1111-1111-----21-3336665233356566876567666888888788881777878775872AAA89AA99ABB67554568989966555555555766557662222222222112222222222222222246665544444233232422222225222222233335422222442222323422243323433333333344343211214444443352222222232443445233222233333213111111122333555554333446344444444444444444332-3443611122254864445545555455-5545554555545555555666555444544454544444444554455543253444444444422223333311113253844445434432433433333332224333334343344445444222222222344454444444444333333333322222221445555111----------------------------------4222131113411 --21433-83514335567455666643333333333333333333446677776657687732322442532324444443332222235353634443433334-5P2DDHAC8A7787679A7496Ph7-98D67878687677587766C9A87C6A56B586B67H4665CB9E*DECABNEJP8DCBE7355A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.7 Carbohydrate phosphatase
[ 240] --------------1--------45585355411122222222443453343224333333-337211 1111111111111111111-11111111111111111131111111111111111111111111111111111111111111111111111112111--1112121111---------------11111112111322114441112222331111111111112232221111111111111111111111123233233233323311111122311131111111112111111111111111-11111111111111111111111111111111111-1111111111111111111111111111111111111111112111111111111133111111111121111111111111111111411-111111111112111111112111111111111-11111111121133322222222211111111111111111111111111112-11111111111111111111111111111111111111111111111111111111111111111111111111111111212111111111121111111111111111311111111111111211112111111111111111111111111111111112111112112111111111211222111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111-111111111111111111111111111111111111121111111111111111111111111111111211111111111111111111111111111111112111111111111111--1111111111111111111----1-1111111111-11111---11111111112112 66337774SZD8A9747458666757655455555555454555556576668656525555544444444545455455444444555687766854445549AC35XUfUYYVUFGKQNMKXQVIxL**O-hVxGLJHWKKXO9HJRKQGCXIUFMTFGlEa*DFJFFoEGZF8BCB*99958bJXb5O*79EEHEH ---------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------- * c.32 Tubulin nucleotide-binding domain-like
[ 241] -------------------------------------------------------------------- KCP--------------------------------------------------------------------------------75789RSRJ-R68---7K8DBVBQ9G--------------58799A79B99A----------2122221111111123211352241121121131111-4244226-1--------------------------------------2--------------------------------------------------------------------------------------------12-7-------2-321222----22--1--1144222132-1-----32K6FI77B222229697D8497676311111111112-334243341161322442453323396871141111221DDDDDDDD7KKD695511111111111112221321111111111258HB8BBA4ERRUTUOJFGIIPOOSLMMKBKRLRHPLW35JJMADBHIVFD7G4FKIBKDHCC1122222A7B7CF87J576B444755719E7CBCDCFDDBEF96DA5433323323444444444A648BDG5579568686537666366B8885578985--28828------55592653676455754-6554555456665443445867AC4335654555554445445612753341-633333333333--2733322BEEFG7627222212112112112999A97922397IKKKIKKGAJIIHB9EG33333333394549666667BB77GEC9C99677111121A3DD7777111111112-----------------------------22-22222AF44 ---------------1----------------------------------------------------------------------------------------------------------------------------------------------3----4---------21-------------F-----8---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.5 Outer membrane efflux proteins (OEP)
[ 242] -------------------------------------------11----------------------- ---------------------------------------------------------------------------------------------------------1----------------------------------------1-111--------------1--2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111----------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------111111111----------------------------------------------------------------------------------------- ------2----------------------------------------------------------------------------------------------------1P-*******dchdkih**h*i**x-*n*Zjed*gmxcYghdbkhT*hygkuMVe***UQnSO****--3--1---1--------------D ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.96 Nicotinic receptor ligand binding domain-like
[ 243] ------------------1-----1-----1------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----DD6-211-JIP3476566574856655565444545445656778889CF6896677754544434345543323444554433443344344244443LJI-G5*V**t*u*gdb*fbi**V*Y***4*m*YVbVvbexcRicYKrYT*c*YdiRRiKOLJ9KGFPKbHK-----------121611-2GOKMD ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.91 Regulator of G-protein signaling, RGS
[ 244] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----57--321-11-------------111111--------------------------------------------------------------------------1-8****z**bfYWbmi**T*m***6***NcVY*XV*rNfbhblNS*WTOu*746J7G33858822Y2----------2-----2------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.43 B-box zinc-binding domain
[ 245] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------1-111--------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------11-1-11-1----------------------------------------------------------------------------------------- ------3----------------------------------------------------------------------------------------------------1Z-*******gejeiig**i*i**y-*n*aphd*dmycWidebjeR*iyhfoIad***TIiPM****--33-2---2----------4222A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.36 Neurotransmitter-gated ion-channel transmembrane pore
[ 246] 22-1--2433333332--111112211111231111111111111111111111-----------111 36D5522422332384566-64229F66666788788EHE28375231144264422211355237B54431111111-131511111--------1-----112313111111111-11111111111111111444331111523322232211111211121334531211111211114342211151133333433133333331422133322123122222113711111111111111111111412122121111122221111132223332222122111111111112322322232232122331222311-2111111111112-111---11211211112211111211211111171165571111122LLM224E6AF444554542436189BA576D5B81C44A55567765L91724555455356545555558442222211111122111111111111111111111235D11AHGBAB7BABD5777799FC88784AA9D7CH8143324664474B3C8441111111111111111214424341122111111111111112144345822111111111111111111111211122112232-131411111-111111-11-1-2-111332------1133--2---1-11----------------------113122-1-----------------4----------11111111111----11111333325427---------------444441212213545439583355429791111111112111-----------1132222111----11111111221111111111-----1-11111111111111111111112112111221- 11--222-732---3JJTIILJHOMNPGGCDEECCCEGIHIGGDCBJGEZObhsGFFD5888865244662363A53244455576234DO7J5754447437222-3F4c5663442323222454535N4-437334342253233413317467554752C459D56FBAA12754b3437AFJEOM7B4122224 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.117 Amidase signature (AS) enzymes
[ 247] 66666666666666662444444211111111222221111121121122222222324222222222 3333333333333333336-33336333333334348444367863333333333333335333646686633336333333333333333333333333333633633333333333333333333333333333333335533366333333333333333333663233333333333336333333C3366666696369969933333366633373333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333334333333333333333336736333333333333333333333333333333333363333333333333333333333333333333333333-33333333333333363333333333333339333333333333333333333333333533333333333333333333333323633333333333333333333333333333333333333333333333636343333333333433333333333363333333333333333333333333333333333333333333333333333333333333333333333333333333333333333-3333333333333333333333333333-33333333333333333333333333333333333333333333333333333333333333333333333333333333333334333333333333333333333333333333363333333333333333333333333333333333333333333333333333333333333333333-33333-333333333333333322243334434343333 55445432B322235452122222322223333333231334422244444343555343553443333443433332333555454553655355334322343416569A785734584252874A4FN8-5684414645A34555466464756557455444945H45542344Y3435574781643274433 ---2-2----1-1------2--222----------222-2-------------------------------------------------------1------------------------------------------------------------------1-------4332- * d.131 DNA clamp
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n6-77G4455865533566565386435537347412522613231213Q12221649C4571355358 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.54 Enolase N-terminal domain-like
[ 249] ------------------------------------------------------------------33 3663333333333333333-3333333333333333333336633333333333333333333666633333333333333333333333333333---3333333333--------------2333333333336336633633333366333333333333333663333333333333333333--3333333333633333333333333333333333333333333333333333333333333333333333333333333333333333336333333363333333333333336333333333333333333363363333333363639933333334333333336333363363333333333333333333-3333333633333333333333-33333333363333333333333333333333333333333333333333333363363333333---3----3---213333333333333333333333333333333333333333333333333333333333333333333333333333336333393333333333333663333333333433333333333333333333333363366333333333333333333333333333333333-333663--33333333333336333633-333333633336333333333333333333333333333333333333333333333333333333333333333333633333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333333336---33-333333333333333333333333333333333 3333333-C6R33333333333363623333333333323313333313333332333333333333333663333665633333333333333333333343336-3589LZFFFO36B666695586Ij6-86B36369636366663638966866-9R33653S637ILB33333y63333D8EL4FC-68333F ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.130 S-adenosylmethionine synthetase
[ 250] 33333333333333433333333444445545447464444444448444444433333333332422 2222222244222222222-2222222222222222322222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222233333333333333334333333333333333333332222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222322222222222222222322222222222222222222222222222222222222222222222222222222222322322222222222222222222222222222222222222222222222222222222222222222222224222222222222222222222222222232222222222222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222221222222222222--2-2222-22222222222222222222122222222222222222222222222222222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222-222222222222222222222222222222222 89767866L676996668856666666666666666768688666676666665666676666766661765866A6-B66666666666C76766666666676D67F7F6A79ACC9BA7679AEACJ*6-88BA6AD6B67567ECB7HACBD7857IbG67VF653N67G988E6*667C9vGCT6BL56D6769 ---------------------4----------------------------------------------------------------------------------------------------------------------------------------------------3-2-- * e.29 beta and beta-prime subunits of DNA dependent RNA-polymerase
[ 251] 33232133334334332222232423311141112111211122312211222134234423441-23 1221112233311211111-12114611111262224697152412112111342111114323424232333333437234311-1143352343-111221342223111111111111111534532334233334433332445322333332224332234445322222223221213111663657335354443444444A4A97544437565566666674322222222222222213311714-33-31-1334433421332333444333334444444445444233333333333344465144414569H999A99BD9D68HH7AB868513667335567A234547536335123311111111214222114733422222222223-12711613532-56655349556553223125434442232333333411212231111111111---------------1-11213323277255345544333344333444536236A73223432322233566722231124311111112112222984F45748A887-6567317C41111352222231111211111111111121111198C4313352546666579555656566951111121111111B6A8472888A8BAB98-88989A98888A9888889CFD89557BA999AAAAAA9A99A777666682-65555655555511311111122221343744552611111111344445444444344454733765434333111222121344465555567657111111111111111116333333--------3-2------------------2------34544837681241 --22322-22-51126665544547443333334444333333333344568A74432222221-1211212111221221-111143358363532222344334-2A133421231111111111228D1-33111111-11111112121112212111-51-2112A115-2433E2223211316214322235 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.22 Dehydroquinate synthase-like
[ 252] 112132-11111111-11222118JEGFJJBA343432222216335856BA924443433---1--- 1223545233321144433-34116333333543334444333455433223434482--5535416468321111221-1154-721LLJK4I762--52-A4232I2--------------111---22--26BAAFC333627C789953244444455665A65614433444443445665511-235445455554555555364425555413544311111123322222122222222222223422232322255443223143-22255532234554444444444433333333333335224452222164127757777374343348863754563514442824461621122651492--224444-16--2--1----444422244-5-1-41-3--6-9--4424424446643466A78686676611111111-----454--------11-------------------21422136622111111311111153111111115887411111313223121112544-1113333333311-67267JBB6H747C335426364A39235566876323411111132222222224455711DC4692775676766757667665767687--45547------97668959999999999-99599999999999999999998844699999999999999999999999932988898888999--3822--222-23757466646624444655611311111223455555433C5655B3334422244243888955555898772224244222222244B322112211111111541----1-1111111111111111---32222231221974 ------2---1------------------------------------------------------------------------------------------------1-3-----------------------------------------------------1------2----2E54S4644-624---24421--4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.286 TrkA C-terminal domain-like
[ 253] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ -----------------------------------------------------------------1111--------11-1------------------------------e*kI*UZSYZhnO**Y*b**l-***UTUZfUD*zFRuVv*WJiaQNKd-----------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.19 MHC antigen-recognition domain
[ 254] --7--1237213EIM6-222122-211121411112112142322122-1--1-12112121131--- 1A727312227216C42A9-9711B2AA9A9357677DFI1APH4234154488B334--443-4227C512111421-1242--1-2543555112--22111974-1--------------3--1--1-2114-11114896-627557BL3233121-365-364A412--11121--1322-1--2454454554DBE7AL39F32653767926263325--141955544431113332241C5656121422229--21122122311-21131224311222252222121221141225522112211151211C2732215423543F9GD526523B3112CB4A3J472231242B4---2-3B333221-245D67GB4733343444444244B-DDGCBHCE6C41A445A4D913154C244B2A7932422FFFFFFFFEA772C25------------1122-1521111-2-43115E131221464447453333448D6635885BA463D1144535A654A312536C1313431111111784627218-4-461A22141964A6532G36423711311111121131111121612213253141392212151747915332253622511--1311-------14242467762731463-74662523448246747739A5324512511461241465418731434342-244434344332--B1121125445516211-111123111131152543421433346633364241175CA321111111114213242344511121949432223262119-221111--------1-2----------1--------------1-2-2-----73-2 ----22--21--2222231244323122233331112222222333426A434723433333111111111-11211111122211-1146727292222221221-2532---------------------------------------------------11121111G2311-631-11133534F3B62-4335- ----------------------------11-----------1------------------------------------1----------11-----------------------------------1-------1-------------11-1------------------3---- * c.53 Resolvase-like
[ 255] -----------------------222223222-----------2222222222--------222---- 2222422222222222224-2533252222225545233342224444444444444444444454244444444444222222232244442444422444444444444444444444444422222222222222222223233433333333333333343333343333333333332222222224444444444444444444444444444434444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444444424244444444444442444444444222442244222242222222222225444444444444444444444444444444444-44446444444444444444444444444444444444444444444444444442222223222224444444444444222224444444444444444444444444444444464444444444444444444444442242444444444222444224242222222222222222222222244222222222222222222222222222444445444444444444444444444444442-4444422222244444444444444444-44344444444444444444444444444444444444444444444444442444444444444224444444444444444444444444324444444344444444444444444444444444444444444444444444444544444444444444444424444444444444442422224-444444444444444444522222222222444 33112212722111211111111111111111111111113111111111111111111111131111-111111111111-11111111211211111112111111724222334332422322531AM2-4262543242232234231335422414A132D1111444624333O3343353481544583223 ---21--------------2---------------222-3----------------------------------------------------------------------------------------------------------------------------------111-- * e.11 Type II DNA topoisomerase
[ 256] 332-3412111111122-222223111-1--144311-332219D45752AC8135-1445-2-3-16 3--3A122333431BCA66-6E22GJ666669FFGF98CD1D7C31-1-352111321--9A91G5I4BD3111112221483221--AA871945---4523453413---------------65377435334233122235245453331111---1--31326466---1----11-144344445229CCCCCC8D7AACBBA466667BBA212A365677655E85444344544444444445543225424424553345323221668333333325622223212222333333333333322233311122B6DP88787981815B6522338134524245AA234336223222233222744311111668AA2116344533343333333-43633933345-4667443545437944324523322345455555515543351-------------------------1111-44551255366337537577777BA7777286693996133362425475665-6342645524433333--14353GBE65A93A6666335356557833431B6511221112311112222-2222-2132333444423323222234522222255235--121-4------34433434444444444-4554444444444444443444442133323322333333332233434443-211111111111--12--------1536365554452222232246666626335926566555366454534622222222232333333335443333333332221111114222------------2-111111-111-1-----111------33122444342353 -1------3234---213143223332111111221-------111222212451-111111----111-21-1-121121---------2-12--11111-1-----511-111211111121111217D1-424-1111111211121111111111----2-111114112--1111----121-31322465343 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.90 FMN-dependent nitroreductase-like
[ 257] -----------------------------------------------------1-------------- ----------------------------------------1---1---1----1-------------11--------------------------------------1--------111----------------------------1--------------1----------------------------11---------------111111---1111111------11----------------11---------------------1--------------------------------------------------22311111111111121111---112---111111112111-12222---11------------------------------------------------------------1----------------------------------------------------------------111111111211111111111112111111111--111---------1-111111121-------111-11111----111111111111111-1-----11--------------11111-1-------231111111111211121221121122221---11111-----32222222222222222-2322322222223222222121222222222222222222222222122223-233333323333--1------1111--111111111111111111----------111111111121111-111---------122232222233222--11111112------1-111111211------1--------1----------------------1-111-1-- 6433HD7-O884889567756766665667866665675666666667877676787777779877776788778888887999876767B768886666586E9A29ECNerYeqYSPLJSRPujQpQ**h-ta*LTMNcRRcYJTNKIXMKiQbNTRCEFHICD9JEHOCFDE7868*76686QIJb6UI55EBDB6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.47 STAT-like
[ 258] -------------------------------------------------------------------- 111--11111111-11111-11111111111111111111111-111-1111111-----1--111-111-1111111-111111111111111111--1112211111111111111111111111111111112111111-11-11111111111-111--1111111------------111111111111111111111111111111-1111111111111111111211111212211122111211----------11-----11----------------1----1--111-----------------------11111211211111111111221-1111-1--1--21111111111-1--112111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111112222222211111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111211111121111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1112111111111111211111111111111111111111111111111111111111111-11111111111--------1111111---------111----1----11111111111-1- 2122E9H-834-36A224344655546553567746332322333365234364333435344223331221243442343233123443-2233544472249761Dt7TfdTdrRPLNJLSN*tJnL**f4wa*INGCYGQcKERKFGRFMtGWGLPCJB*JCC8ZEMD8BJD6CEKn89AECFCLI3FHPNDDCBG ---1---------------1---------------111-2--------------------------------------------------------------------------------------------------------------------------------------- * a.140 LEM/SAP HeH motif
[ 259] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21--234----5-------1---1--------------------------1--------------------------------------------------------221***wp*sXDAHV*Q**F*d***3rp*9MDI*bd*Q6eJDB*D7*O*y*****AfA9sDbXGl*74----2-----1----1-------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.22 Serine protease inhibitors
[ 260] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------9---c-----------------------------------------------------1-------1----------------------------------41-*******jWZZlwo**a*i***I***OkdV*dryaHqiYU*OL*iqjn*ask6MHF8QFFhBDEHH1-------1---------1112- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.16 Trefoil/Plexin domain-like
[ 261] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3423**A-G73-648313434644424445555445333333344511333333233232323221-1121123211-11122222222223143342446437C6-3j7*ppcfscRMOPQrW*kPrM**s4lZ*HPTKZPTlaHTPQKWIIqKfRQWMSTLXWPFUKUGH**D196EH78557J*h*3*H141H878 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.8 TRAF domain-like
[ 262] 111-111111111111--------52224-22----------------------11111111111--- 3432221111122222222-2422422222224333226622222242122177542222225238A3222-------1--1B411222222122211113222222221111111111111122222222222233333---343333333333333333333333333333333333333332332222222222222222222222222222222222222222222212222222222222222222211111111111111111111---11122211111111111111111111111111111111111111111122112222222121122211112111221111331212222222312113145333333333735533333343445645645561774787747P42EBB9B9CCBEEF9A333AE86666IGP333333335333833322222222222222222232222222222C356323344355555564333556A55553557646432233753333333335223352533333333333333321312222222222122222221222223311111111111111111-11111111133332323833333333333333333333333212333422222233333333443333333-432333333343333333333333334333333333333333333333333323333333333332223333333333333552222222222222223222224333536666666AA786638883333333333333323333333333333333333333323312222221111111121211111-111111111111111111122222222223322 44--443-C32-3344434444344433333233333333333333333344445444333333423423333432322343233333345343353333233452-4A3K88678A786456587595M*7198G67738766636544774A755575AA4776465A446864445V6555562373553641537 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.250 Folate-binding domain
[ 263] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------*******jfffl*m**d*****-***Xijd*iy**QurkavXW*j*up*GWNFfT*DhIJKFLO6------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.17 Cystine-knot cytokines
[ 264] -------------------------------------------------------------------- -----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------4------------------------11--1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2222--N-2----------------------------------------------------------------------------------------------------D*u*ku*iTWUTVcVrkVzT**h4sb*PZZYWPVXRHTSZMYSR*ZkTa*******J5Noa637*G--------------------2--- -----1------------------1------------------------------------------------------------------------------------------------------------------------------------------------------ * d.171 Fibrinogen C-terminal domain-like
[ 265] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111--5-41----1--------------------------------------------------------------------------------------------2O-*i*f*k*cWbSYlUvsS*m***1*h*XVVOsQV*lNXZUTqOS*VpgkbSKHEvV41222K37NT-1--S53511--------5----6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.14 Kringle-like
[ 266] ----------------------------------1--------------1132--------------- ------------------1-1---1-111111----1--------------------------------------------------------------------11-1------------------------------------------------------------------------------------------------------------------------------------------------11----1-1-1166--11------------------------------------------------------1111111111--1----443-----------------------------------------------11111--------------------------------------------------1------------------------------------------------------------------------------------------------------1----------------------------1-----1-12-----------11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--3--1------- 3311IHC-vQA5JJZLNOJQNOQXTTPMNHKJJMPHHKGHFJIFJLKJKOPPYQMNLJKKKKFED8BB5C66EAD56466ABBCCD686LeMNNLLIFHFIGGaXW1BrJMGFBECBC9AABHALN8K9PxH1KDL7B98JADHE6CC96JC5K9LDGB787CKE9AJEIJBEMF8ECL*LJI6COIULMFFKOCGGHS --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.120 Cytochrome b5-like heme/steroid binding domain
[ 267] ------------------------1------------------------------------------- ----1211222-2--------2---1------21111111---1--3-15543332-3--1-271-1121--------4--1-------------------------2-22222222222222212121111111111-----2--------------------------------------11-----1336222222434422225H786A62425441824KKMOLJ321999898899999997333392-2CM2-425EC--IQ1431243445947555578A87878A7877555555555555524411-444A13-4F3333333625-T--1232-1-22312--------1--199712352-3111112222121111122121111111111112-11111222111-211122122211111111112222111--------1---1112------------------------------1111111111112121111111112111112211111111222112112111121211---41111111111-112-343-121-11111-12111121122222211-------------------------11968111111151111111111111111111--1111211-111C755565DCCCEBAACB-CE9CDC9CCDCCBCDBDDDDBE77242CA9BABACCABBCBBB6CA7997A4-766666666666--31----------113155574623333233522222-2---3133333433333333333111111111-9AA8999998A9AB2222222222-------922111133333333221----1-1-44311444145322--------1----161- -------------3---------------------------------------------------------------------------------------------12-AJNEPFCAADDCDAOXBI9**F1LHV9BBBEBBC58CAA7GB7XC9AB937P99644E43F5B532---1--------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.112 Phoshotransferase/anion transport protein
[ 268] 111212222222222211-11112222222231-122211111222222222211112211111-122 22111111111-1111111-1-11111111111111111111111111111111111111111111111111111111-111122222--------1-------1112111111111111111111111111111111111111211111111111111111111111111111111111111111111122211111111111111122222211122222221111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122133222222222221222---2-3112222233222322222222111231111111111121111111211211111111111-2212222211111111111111111111111322221111111111111112-1111111111--1111111111111111111112222222222222322222222232223232222222112222222221122322233233211111112222322221222433333224342333222212113422221222211222222222222111112-122111111211121322121222221--12222------21111111111111111-1211211111112111111---111111111111111111111111111111-122222212222----11111222221222---------------111111111122222233323333322221111111112111211111221111111111112----1121221111111111112------1-1111111-11111111---2122222222111- 2--1435-732-3453234223334-1442311443133343312243434433324343331-22--112--21232221112--2221342454233333265B1521EUicbZTNOONIVS*mLpQ**m1qZ*LMKOZKQhHKRLTQTKIaLVSON99AGFGB5VCDG8FB6322322234265393552123251 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.137 Non-globular all-alpha subunits of globular proteins
[ 269] -----------------------------1--------------------131--------------- 1352C22222222232224-232223222222333323223857-3443211---211--663277747G-1---1--22212----111---------14111431-----------------211111111-211142---E11233115--11------7111SUPC------------411-----539222222222222232HT875B2226682P3111111166111111111111111111111-1-24--11111--13--1--------------------------------------------------384J7656565467572764111A59--4115277442C71429A83111---53464343368GDDB879A9A98889889988A-DCBBABCEBB61AB9BCBCEFBDEAB84589A6866678--------1---1244------------11--21111-11-----142211232241112212333322-15333141122111----35144425121--13111-32-------32-241424-3-2--1-----11114121122227941-----------------------26--3422622-3-33334333444433444344--5121-------33254333223333323-2332222222232333332242233132322222222222222322342233-233333333333--3211111----32522---11----------22223323575444542335222223332---------152333333323222536676A222----1121-------------------------------------------------------2 ----331-----11---1---111--1-----------------------------1--------------------------------------------------14-cNQHQHQIGFGJEGUSBNFS*N-NHaEEEFOFDIG8JJEAJEAPEEBEU6DII3582457645J12136644112542G-63------1 1---------111--------1----------------------------------------------------------------------1-----------1----------------------------1----------------------------------------- * a.20 PGBD-like
[ 270] ------------------------11112111211-------111111-1111-----1-------11 121-211111111121111-12--1211111122221111111121111112111111--11111111111-111111-1111-----111--111---1222231221--------------122122211213---1111---7345332112222223241132121121111121111111----11-11111111111111111111111111--112111111113111111-11111111111111111111111111111111111111111122222--2222222222222222222222222111111111-11111111111-1--111-111---111----221-----------1211-2744A-----45I794335643622222122227-443342428G6-A556IJIGNGJG3329529685774961111111134411212-----------------------------25788-145565556572444455645555366534344111223313351536236431-163111111112422222211123111111111111112123637A111111111111-1111111111-11234434257624345543385555437346367--13311------22111311111111111-111111111111111111131213111333333333332323321-111111-111111111111--2411111335322A6511112-111112--177657722532356555643454634224322222222143343333357745665555534411111-12221122--------111------1-11-1111111-11----1--1------1221 1111772-7342334FJH9IHIFIGBHEE9ECDGDCCECEBEE777BCJVGJWKBGBDFABB3332233433344332332333334445D3JEC94664336535-4R6F7876C854852A5A95I4IrD-99D5737833865654473396655866238641934647652444N3443675AE8E9B5A445D ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.88 Mss4-like
[ 271] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 454566L-SDB566747556666666666676666566564666666666666666676666655555-5555555536555456587746575664444675A9C2IZAojidifoWTVaVRQpeUlV**ZGkU*XSUWaQWZSTURWYaaWqSdVRPKaiHXOPFPGFV9AVJ4DDA*86588C7DH58999YaVUK --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.148 Hect, E3 ligase catalytic domain
[ 272] ------------------------11131111111-------12211211212--------111--11 2221211111111111111-11111111111111112142143611111111211121111111114212111111111121111111221111111111111111112111111111111111111111111212222211121333333322332223223331545322222222222211111111111222221221211111211111122111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221311111111211118822221111112211112213111121111141131113111111111211111111111111111111111122111111211111211111111111111111111111111111111121122222222222222122222222222222112121222222222222222222322222222342222222233232243232222322222222322221112231211111111111111111112119989C512111111111111111111111111122232111312222222222222222222223111112222222224222213333323232-33443223223233333332222322232323233333232222332223311222222222222111211111111121212222222222222222222321322222222233432222223331111111111332322222222222111111111111122211111112222222221111111-111111111111111111111111111111111 3333B661JA934485633455655555545455555555545555655655575857655598888868AB87DFD7CD8888888675A6675C7665554ABG37EOAFKHCEC898B697JF7N9o*D1FDN7896J8AC99A779A56O8A8AC7DJ7EB98P5-759685797*66687OORX5KB69CDFF6 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * b.130 Heat shock protein 70kD (HSP70), peptide-binding domain
[ 273] -------------------------------------------------------------------- E6I-------------------------------------------11-1--111-11--11--1----11------------554799A86-C23---274BBE8GD6--------------252354644376111111--2-5425324--22212424243D2673-------1-----2111--11312222222222222221111212212112123------A211111111111111111111-----------------------------------------------------------------------8115-------1-1-1222--------1-13133622312-1-----12F1FF77C1111178HFPG8GFDFEB34243443223-KPDCKGKH565-B66B989877458I6BDB55545543544444444968433A3---1-11111--1-22132111331----1439923332589989754443669666665955EABCK-3FGD79779NG97848GD9B7A57-------9696BH55C1487836E331-6A477C855AC8ACA-641---1111113233333335324868545GDCIABB6CFGFDFIIJEEFJDHQLMF---B86B------34453543334333533-344333433434333333357645232222222222222222253213233--433333332333---7121123667G8A54111--31----1---44454391116768786A9B779879679---------B5779444449ADBBDC76765366323233E9DD57FE11111111-----------------------------------11-6C21 -1-----------1------------------------------------------------------------------------------------------------------------------------------------------------7----C-1-------3-----------1--A-----8---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.225 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
[ 274] 445443444444444445555555744754563-3334544443535732343244444444444--- 3343355666632655555-5533555555555555555533332334322-3434-3--33234443333-------2335322344111-----1---313223311---------------3333333334364475---3544333332333333333322333331111111111113333311-413555555453555555333323564233311333333354233333333333333343334-1-11-3---331311--11------111111111111111111111111111111111111222111146964555555525234111444211346-254666588267744143113335334-11-1447447484444444444444444-8797998A744-5333334333745435364454556554444444443324454-----------------------------33333145555556565444445544444444544555434444444444444444442333331111111---543-5769575857555-5354537585555556643333333333-3222222244434335534223-2-25444434544445455455---1533------44443444444444444-4444444444444444444444442324444444444444444433344442-333333333333---2-----111132232212222222222222222222222322444434422333322221-1-1111-4444444444444442233334334----2232331111------------------------------------14411141113311 ----222-----2233333444363633313333333333433333233334342444344411-111111-11111111111111---35333331111313443-32-4465732332231374373CQ626694433733533433373273433422F34431422535332432E1214431573333354541 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.57 Molybdenum cofactor biosynthesis proteins
[ 275] -----------------------24222-222-----------22--2--2----------------- 22322---------32222-22--2722222252222222--23---------31-----322-2-3122---------------2--------------22222-222-----------------2223--2-3----------52----1--22--2-2222-3--13---------------------2-----------------2--------22----------22-------------------------------------------------------------------------------------------4----------2-2-------------2----222--------------2-52222-----2232222-22425------------421223-2342-222222532223212222231222323--------2---2---------------------------------22-2-2----44444422222222-222222242-422-2223322----3----22--2--4-------3-2-22-232--2---2------22-2-22----1---2---------------------------22422242-242222242444224--2-2----222------22222222442222222-422222222242222222222222---2222222222222222222-2222---22222222222---4-----4444--222---------------22222-----24----222-244422222222222222-----2222224-22--22222---2222----22--11------------------------------------------2---2--- ----125-632-3267BDC7787879A5566555556766666676659ADCANCCD76777312-11121122211111122212---K7FB6452222425426-1J2nFF8EAOFAEFDFDCEDJBX*G1JALBCH9CDBAC7FCI9BDCOCC888Hcm1BO*aFKLfGH722897k59447****A**9IC78C6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.93 Heme-dependent peroxidases
[ 276] -------------------------------------------------------------------- ------------------------------------1------1----1--------1--2-----13----------1---------3373-1------72224K1-3333333344433335-----------------------3233-----------232----2-------------------4--------1---1---1------11-----31--------4--------------------------------11----1----1---111111111111111111111111111111111111111111112---32222222-2--3-------1-------------2-------1-k9----------------1-----------------------------1----------------1--4454444454---------------------------------------------1-----3------------------2-----2----22------------2--2-1-1----1-2222221-------1--3-----1-------------11113122-----2------7-----------3------21-4---5HHIE--2HIIGCK4-G-9---3--------------1----------------------------------2----2-2-2-22222-2--2----333----33333333333---1----------32-1-------------------------1344443363453333222----------111--------1------------------1-AA5599222-2----------------1--------------------------1- NFB997M-*lhQAAA1-11113111131111111111111111111---2---------------------------------------------1-----------7*WQOOWYQRLJEDGUHaUAYL**X7eQl8JEERGMYG6KCCASAAcNRILRCCFZGJ6BE47U12gP-JKK*9B89HHLNZ1SLGNGdUTr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.76 open-sided beta-meander
[ 277] 111111111111111111-----12112222212332322223111111111122323331111--1- -1-1111111111122222-2222222222222222111111111111111111111111111111111111111111111111-112--1111--1111111111111--------------11111111111111111121118999998877776577899A68C96888987876986---1111111111111111111111111111111111111--11111112111111111111111111112-111111111111111111---11111111111111111111111111111111111111111111111211114443344141111112211-1-11221111211112211111---12-1111-----222227343333222222222222-33333223111-11-111111111321112212222211-------------132-------1--111111111111111----1--1--11111111111122221111222212111111111111111111111111111111111111111111111-1-1-111--1221------1---11211-2------------2-1111111-----111111111111111111111111111111111-1112111-11121111211121112-11-11112111211111111121111211122222222222121221112111111111111111111111111111111111111111111111111112111111111121111111211111111111111111111111211111212111111111111111111111111-----------------1-1-1-11-----1--11---111111111111-1 43-1666-611166979866789A5488889888676888777899897898678696888885699966A75968A5898998698886C997798797576ABH1CB2HGHKKF9CGCEFGBURDOCZ*R-PMR7GAHRCGVHCFC7DCCCHAGEEJ757A98BAOFMCBD95D9C8*99499NIEN9D86676665 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.23 Single transmembrane helix
[ 278] ------------------11111-22222232-----------1121211331--------111--23 2232332333332342244-43223444444232223555333333323333555433222343465444311111112222342222324322221--242634333411111111111111133233433333433223332233333333333333333333333323324343333433333322233322222323223222333333322234323222222224322222222222222122223221222221212222222222222222222222222222222222222222222222222232222222222222222223322222222232323222222222222422222222222223433422222225552343345344444444443-54544546332366654584458753343326333323333333333333326332232222222111111111111111222223343234733766667666666667677766676456545446644334444434473222642222222322335452224242544432434542333333346233333335454724222222243346235437357243543333333333334233532-2342311111133444444444444454-444444444444444444444444684434444444444444344444444334344444444441142222222332133451113331333333333333334333336667476865544356633333333343334333333333333333333333333222233223311111111211----1-111-111---11111111121223222222422 11--232-311-2233433333353522212222223222212222333353333434333322222222222222212222222222223242224444124222-231B454536445444443384GV4-56B5343544533443343374944532635323433532542443F2233364563534342225 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * c.65 Formyltransferase
[ 279] 11112122112111221211111222223133-----------43-13--222111111114431--- 244-B11111222165411-14--37111111767623941B264132123-41312311214252648B2----111212131-11111----11---22-1-2121---------------11111111111122222---52-11211-23-----1--1---43311111111111112211111-2-6A9B9BC98489BAB9213336A881114443222221461333333333333333111221213311111222222512-125752223111323222222222221111111121111222111---1-1445333222222212331111111121-211113-11-311111-1--21422211111173F9B11321-4-22222222216-988965982B3-B8867788A9ABA33212451111315222222221342-325-------------------------------29-39CA56ABBCCB433337788554527B5A99FB-1445356338444I7-42-3438311111111-2142-34-113--22221-66313551323226B5421111111111-1--------1--23254-111322222222221133212312113---2323------66632635556566654-5565756555565665664888533335555555555555556B53444451-511111111111-----111122221-635---------------87778152256-DCDE99A87A8B94987144435434---1323223531348613133---1111--1411-----111--1--1-----1---1-2------21--1---211222222226-1 11--792-B5212267AB78BABAD876755456666555555455997C569857645322112111111132111111111111111A64A6523441321915-2b2B11122-2111122222234B2-2231222512221212121114212333345442323524322643g34292432BB5466A4666 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.33 Isochorismatase-like hydrolases
[ 280] -------------------------------------------------------------------- 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111--1--111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111111111111---1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1----11-11111111111111111111111111111111111-111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111-1-11111111111111111111111-1111111---111111-1111211111111111111111111111111111111111111-111--211111111111--111-1111-111111111111111111111111111-------------------------1111-111-1111----------------------1-1-------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--1111111----11---111111111111111----------1111111111111111111----------11111111111111----1-----------11111111---1-11-111---11-111-1------11-11111----------1-1- 3334CBD-G7534564555555554545555555554555345555455555555565555545554535565456636655555566636454455555444CAA2FR8HhWWiaPHJHEINKrpIgO**eBpQ*CJHIYGLYI9MIIFTHBjJMKJMBDMFAAF5FDBE89DB3667k76666JGGK5MB999999E ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.45 ArfGap/RecO-like zinc finger
[ 281] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111--------------------------------------------------------------------------------------------------------------------------------------------------- ----TUF-----E9F444455665676656454655555545544455444544444454446555565666565656675655552227BA4C663233346JLX1V1SMokZiegZWX*Xid**S*b**e7*d*TSSnlTVYYNXZRTftQtYSPWR7FKHEFBBSACQ8GLC------------1-4----4444- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.117 Ras GEF
[ 282] --11--1111111111-111111111111111111112111111-11111221111122-1111--11 1111111111111111111-1111111111111111111111111111111111111111311111111111111111111111111111111111---1111111111---------------1111111111111111111111111111111111111111111111111112111111111111121111111111111111111111111111112111111111111111111111111111111111-11111-1-11111111111111111111111111111111111111111111111-1111111111111111111111111112111111111111111122111111111121111111122111111122221112222211111111111-112112121212222222122211111111112222111111111111111121111111111111111111111111111111111111111111111111222211112222111111111111111111111111111111111111111111111111111111121111121111111111111112111111111111-1-------11111111111111111111111111111111111111-11111------11111111111111111-11111111111111111111111111111111111111111111111111111111111111111--1111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111--------1---------------------------1-211111111111 5512EPA-G663867666566666566555555555555545555564656666666666665555552G5553455465555556555696666D7986667CDE1AQBJLSOUVMIMEKHGKaQHVI**M3OKaBDJDOIHREEKJIFGGGPIJFHICLJBBAD9K58GBE984588M555668JOO6KE56MLMJ7 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.143 SAICAR synthase-like
[ 283] -------------------------------------------------------------------- ---1111322111113322-24222322222243323333-22211111211111121--11211122121-111-------------111--2------1---111-1--------------122-222111-2------------------------------1------------------------1121212211112111112122232211111211111111111222222222222221112221211111111221112212111312222222222222222222222222222222222222222222221111111111111121111111111111-111-1111--1-111111--2---2221-----1111-1-1-1---11111111111---1------4---22-1--1------11--1-323322---------1------1-------------------------------11--211-1------3----223-------123-1--12--11111123--3-11112122----------1--12-111-1--------1-11-1-12--1---1-3---11-1111-----------------1111-1111111111----11111-21-------1-------23-21312222222222-222222222222333233244421--12222232222222224-2222222--2-------------------------2-1----------------22112121111-111111111222211111111111111-11-54443111114444444352--------11------------2------------------1---11---------------11 -1--41--1-----11-33--21322311-----1--------------1313122111-----1--1----1---------------------1-------11----I4*snpcfXUROMSyO*zSpV**l-mc*KQRVqQTodBTOUKiMHhLeJLM8763AJMVFAHDNX36-211K34344658614A663233A --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-- * b.60 Lipocalins
[ 284] 11111111111111111122111132233433---1-------1-1--1111111111211---3-11 243-722222211221122-221122222221222223442222111112224342211122133224443-222111--1111-111334313222--34444743341------111----11111111112122222111316342221111111111121-233311111-11111-11111111-1111111111111111112222221112221212111111-1111111111111111111111111231111111111511111121111111-111111111111111111111111111111111111111-111-1-11112121-1121113141-222-1111111131-111-1--317111111111112131111111111111111111-11111111222-122223333223122213322333322--------------11--------------------------------111----------111111111-1111-1-1-1213--22322---1---1----11-------------12-13441-222121222-3231332335444552211111111111-------------1--222344224333434322233333323323--12111------11111111112122221-1212122211121221222111113321111111111111111122111121-111111111111---3-----111123411---111-1111-11133333332331311111111211111222----------2223222222222244555555553333----554455--------11------------------1-------22122222223613 CB45A8C1L452A9B68A846675654655656777465565576567767767567566666583443643548343444665766765C888786677446CB719HDFHHFFHFBD89DDCIFBMDf*G-IDL9D98DCDIF6EDCBEC7IDEECD9C9CAC98E89C67B78IHBz8A7CGNJMP9RFGC6779F --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * f.51 Rhomboid-like
[ 285] 222222222222222221222222--------222-------------22122222222222222122 3333333333333333333-33333333333333333333333333332333333333333333333333323333333223233333222222222222222222222222222222222222222222222223333333323333322233333333323232333323222223222233322332233333333333333333333333333333333333333333222222222222222222223----------------1-----22222222222222222222222-2222222222222222222222239322222222232333332333223223223333333333333333233333333322222333333333333333333333333-33333333333333333333333333333333333333333333333333333332222222222333333333333332222223333333333333333333333333333333333333323333333332233323333333333333333333333322232222222222333333333333333322222222222222222222222122333333333333333333333333333333332-3333322222233333333333233333-3323333333333333333333333333333113111333333333333333233333333333322333333333333333333333333333333333333333333333333333333333333333333333233333333333333333333333333332232222222222222222222222---------------------22222222222332 3313646-721-446221221111111------1------------11111111-11221-121122211212122222221112211133323344332122363-534D7977467554663794C4Fj91ACA353693466355459348356663446A553956795B54568w88866677G2D87686752 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.101 Ribonuclease PH domain 2-like
[ 286] ------4222222222-46542234--24646-112211----34132144342------------42 3341532333332346644-4511744444435555448544442221411134533311446143455441111111111133151311113111----3-224441311111111111111123222223212-22--111416555557557755555555557575353533353533443331113454444444444454444455454444545211-111--5521111111111111133332----------------------------------------------------------------------2324A333333373715444675332111221466954113382213113135444411111576774445224455555555555266666666453-6554556555566744346533335445555555533335633---------1-------------------13544333336856888699996687999987888466414446544445444544446464331353333222344-23353443344441535155562335324234111111111111111111153155336254444143433333443333333443443--26321--33355441544444444444-442544444444434444457557334555555555555555554444444314444444144442313---------45466333313111111111444443434444888867866686656561111111111544533333455551-2333322233334421443333--------11------------1------1------1111111111453- 11----2-1-----333333333333322222222222222122223333333323333333223212222-22222222222222222343332322223-3522--B-------------------------------------------------1----1---------115655x55555F6ED3656623336 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.134 Nitrite and sulphite reductase 4Fe-4S domain-like
[ 287] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1-----------------------------------------------------------------------3--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2----2*-----------------------------------1----------------------------------------------------------------B51***uo**YaQNb*V**S*l***-*u*McRXwal*tElfLEzIE*R*kXw9478Xa31-----3TB-2--1-213------2---12346 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.24 TNF receptor-like
[ 288] 11-1-13555555553-212111231122153-1111111111-----111111111-1112211-11 5353541222221286433-3311473333326585A8KO2319272212229A8343--549134749411111111----6-11--11111111---1333441423---------------11-11111-115454411136-211221----------11111111-------1----3332411-51122222242442322243221124215714111111115421111111111111122221-------2---222211---11------------------------------------------------12--1-----------211---------2---1331-1-1-3212111--2-2C554-1--146IEF2148577555555554554-33C33C47D66-B66977A87A55A98445993233388--------442-3522-----------------------------31CY4-EC959FGIFEA68884DDJDA99929KEX9OFD25BB8BB974CAG4JD442----211111111---389221--1-1-21111111111111-222236-11--1111111--1---------11111111311214312333333233332321324---121-------32221212331211135-3515212522315552555556225516463656666656536743144451-144466646666---3-----11111124A--------------34444422123937777664B267772344111111111-111222222223252244444333-------1----11--------------------------------------1--------212 ----333-421-3226664C775GCE93333333335444444333545AACKJ7785444421311111111131111112222211132263223222214322-2D36463232321133234242BN5-435342143442122-13-13333265532756443452253222371111244664332344335 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.177 FAH
[ 289] --1-1--11111111--1-----21--1-2111-4121422215523337DCB1----11-111---- 6DA3H314554133DFG87-8F11FH88887AJHGHACMG353O2451-32-323112--35A-816AC9-2444-----315--1-11141-2------415482322--------------11---11--11-13322111113-11---11----1----1121251------------53332--1113333332432334225323322235-11221111111283-1111111111111111113-21-11-22-22111222-1-1-222111----12211111111111-------------1--111---1-21152223243331-111--------1--2--4411111121112-1--3-65653-----95SDC3265356422222221213-11811A1AA87-CAA7CD8BF8BB9623358F545576A2222222277515612-------------------------------294-5C95AGGIGGL86777EEGG99984BJHVAGHD-2EE83338683E6E8-622-11532222222--2633-8231223-43--5-32122163135534412--2---1-2---4-------11134424262226351123233-323431312-115--1-221------46222241333133311-3111323121335111115CDC442122-1211211121112162221111--533333333333---211111434311114333515-1111112-44634233216-555564943566957451------------4------322166225222222-----1411----------------------1----------1------1111132233-43- --11121-111--3178874565675943234331-24344443332323569B33242212-1111112121111111112223211121382121221214232-13254643582322343442438G3-436322153353223334325344551342411-32-4--31---1----12---17---22-111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.152 AhpD-like
[ 290] 22233332222222222123333422222322333333333333433322333325233322112-22 4442223222232222233-33224433333354442497244432323332233222224433365343311112111223433432343414331--353343332322222222222222233343323343332233332345544453344222222553344442222222222222222222222233333322232322222222223222222221111112223333332333333222222112111141112222111123312222221111222222222222221111111111111222221222132143444433532332222222223211223333233242332223222443122222222444352223332312222222222-22222222222223322333342233222224333322222222222322223342222222222111111111111-11222222444244444455545344444446444444556557512444433443336333344333543333333334344255353444444453434533334445435443233433333333323233323333665554333334465555355555555555542-3343422-22244444444444444444-44444344444444444444444433444444444444444444444444432433333333333223333333444443532444544333333333444444433453333353445555534444343233234333455555544552222222222222223423333331311111111211111-11111111111111111-123122212223333 1111112-21112224223234345423322222222222212232222223232223222222222212222222222222222222223222223232242222126193542211111-1121111141-11211-11111-1111-11111221412213312111112123332H3333345692553253333 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.115 YrdC/RibB
[ 291] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 6313DAG-ZF9778C9LI6466566685477689656878577563B5C97B7B89B88769635444234454434243433353233QPDL**p2434I64ECE-EgG*KSMQLHICF9FIFnUBiE**V1fMp9GBELEHKFBIGDBICARDSEFJDIHBLLw8QRSRBGI73*GcO886*MDD7IBBEB8ENKP* --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * g.85 HIT/MYND zinc finger-like
[ 292] ---4-3--------------4--4--------1----------1--1--52-1--------------- 4NW---------------------------------------1------------------------------------3I8-2-I23223--422-114211151112---------------2133232331243333111-1-1--------------------------------------11----------------------------------------------------------------11-------------------------------1--------------------------------------25--2222211111-2--1221---1-3--3-FE231212Q1-------1CJ2--------114271--162-2------------13422123-----22---212245-21--41244232-1---------11--831-------------------------------445--22-32----1----------------122342--22-G-------L----31-2--2-------8891474GHG5JFFBGIIHK2***n***5Fyz*zAH5B36675335526-4-------4746A--96-1128-1-2KILLI2NcLMMKQNeYM*O---4274------62--7--6666666666-6656666666666666663---44---555555555544555545526666--322222222222----------111G13--555565546664445---------1-12232-1--2-1-14------------1577C555557B688--------------1291441111----------------------------------------------3E21 -----2--2--2-1-------------------------------------------------1--1-------1--------------1-----1-------1-1----1------------------------1----------------------4--1-1---------2---2--1-1-------1---1--1- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.138 Multiheme cytochromes
[ 293] 11121-11111111111222222122222222111111111111222211222111111111111111 2221222222222223333-32223333333323333232222222222222222222222222222222222222222222222222221221222-12222222222222222222222222222122222222222222222246222222222222222222442222222222222211111222222222222222222242222222222222422222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222233222222244242223332223232222222222232222222221-1212222222222222222222222222222222222-22222222222-2222222222222222222222222222222222222222222222222221122222222222222322222122222222222222222222222222222222222222222222222222222222222222222222222222222332211222222232323223222222222----1---------------1--1-223332222222222222222222222222223-2322233233332333333333333333-3343333333333333333333333333233333333333333333333333333333333333333322222222222222233333333333333322222222222222222222222222222333333333233333333333333222222222222222221------2222222221222222-22122222222-1212112-11--212221112 4445555-D553555455556555555555555555455545555534555555455555555555555555555454555555545555A5555565555455755565A685555644455466484HS9-7594554745743554365374775557546566654A44745555w55535889H5B65566554 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------41-4- * a.80 post-AAA+ oligomerization domain-like
[ 294] 112112111111111111411n5212222322113121111113315222222133224221113133 2111242211111211122-21111222222122221111221111123111121111112223322222223333334133112323554615221--2312221221111111111111112111212212321111132323312-1113311111111112312-51111111111112335622232133444334444433412331243422121334444442333333333333333333512322244232314422443322223335555455444444444444445555555555655444333444418658665667676647446554744233221255374233322221334251311311111112113221611322222222222-111121112131222222122211211222242222222111111113111225611111111111111111111111111111111113111122112111333322224444241322233116442223322441221132224311111111112123A435257346553124124223122222241222221111121111111112223222866221221143444434433343444454113221211-11196457859BA99BBA99-799999A9A98A999999A7A8664489898989988899888698999983175565556655511121111111112122155545445553444411111111112133331111111113111111111111156664444466655221111111111111111111111---1--1-21311111---11-11111112111---21222232222132 1111222-311-11211121111111111211111111111111111111232211121111222222121222222122222222311121111211111114231252A23222111211111-1112A1-112112311111112221212212111943111-111211231342H2222142261132682337 ---3-1-1--------1--2-1-11----------34313--------2-1----------------1----------------------1-----1-----------------1-----------1-----------1---------------------3---2-----1111- * c.7 PFL-like glycyl radical enzymes
[ 295] ------------------------1------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1-----------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 1111--M-1--------------------------------------------------------------------------------------------------3--*urq*jZTQRNVYVmjLxW**f2xVyDSSThRUYWNVVPMXKKyTPQUgi*kcz*51613416*b1fgI*1118-DLJb-DT------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.12 Lipase/lipooxygenase domain (PLAT/LH2 domain)
[ 296] 11-111------------1111121-------1---1----------2111111111111--11---- -1--2-1-------12-11-11--2111111111111344-121-11-1--------1--1---2133321----------2------------------1---31-----------------1----1-1-----1112---3-211-111----111111---2212--1-----1----1-2--------232331221423122-1----3222-1---1---1--31--------------------211-11--2------11-------------111--------------11113121112121------------11-------1-------111--1---11----1------1---1-11--31111-----111111111111111111111112-11211211111-222122132221121111111111111------------1-11-----------------------------1-111-3111-1111---------1-1-----1-5--------2--3--1---1---1----6---------1---211-1----------------1-------11-1---------------------------11-----------1---------------1-------------------8122-1-1121-1--112-1-121111111----1224--4-1-1----111111111-111---2---1-----11--2------2112--1-----------------------------431322-1-DAC5-C8A----------3-1-12-1262-----2--------------1--2211-----------------------------11------1------------ 2122JOn-313-44644543454553423333333343333333334555547745J563223111111121111111111111111118J34CCB2233112211-E*T*VXSSlUPNIJOQIsYIXJ**V1XPmKLIJXGLWMFQMJIRJFeKaIOlLJOJWKD3535754FR-4238---3-EHIU4LN1254868 ---1-1-------------1---------------322-2----------------------------------------------------------------------------------------------------------------------------------42--- * d.166 ADP-ribosylation
[ 297] -------------------------------------------11-8--1313--------------- 1-2-1--1---------22-23--1122222-3333-111----11------121-------1-1---24--------------------6---------1-3721478--------------1----------------111--22432214422------22146652------------333-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-1-111-----12322---11111----------1-11-11-1--21-111121111111---4142-111132-111111111111----------------------------------42-2-1-------------------------1---2----11--1111111----1-------------------------------------1---121---------------------------------------2-4---1-------------------------------------------------------------------------------------------------------1----------------------------1----------------------222---------1----------------------2-----1-1--1111111111--------11---------------------------------------------------1-3 1-----S-1---4577BC73443373355554555553232333335576DDCDFG696664533464324223224331322122444DC8BI9A989E78BPFW-AB-xUUPYYnLIE8MLJdUMhLh*M7hMoHLLBYIMMKEMKEGRHIeMPUMG3-B37T*5*CGG55I-1VPC99A7VBHWu*7YHC5----3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.118 FAS1 domain
[ 298] 111-111111111111111111-1111112111-13333333313122-2332-11111111112--- 2322222222222222222-22222322222222222253222222222222222222222222222333222222222121222312222212--311222222222211111111111111221111112122222221112245333332222222222333333322222222222221111122222222222222222222222222222222222223333332322222222222222222222222222222222222222222222222222222222222232222222222222222222222222222232233222222232322332333321112333322343223331123222223222212215522342232222222222222222-3342463322222224222222223222132232332222222222222232332112111111111111111111111111111222222222233323223233223344442423443442233322222232332224222221222222224422323322232223222222222234422223243222222222221111111111122244343222223242322223222222222222212322222122233333333333333333-3333333333333333333333333343333333333333333333333333233333333333322222222223333232322222222222222211111111118233333333333443222222222222233344444444444222222222222222232333333111111111-2111-2-223323222223223311113222333333222 3311222-A3224442222222222222322222222222222222222222222222232222222222322223313322222222223222223222222557137245A455633343336D293Hr7-85E2322533331332532243423334445336A24749326AEA*44497OCPM2G99786998 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.49 Pyruvate kinase C-terminal domain-like
[ 299] 22-1221111111111111111111------1-------------1---111111111111-111112 123151211111-111133-321121333332111122223424442222222112211132424324342------1--11221222--11-1111--12---41-2-11111112236666122112-31111233341115252241111211111111131222211111111111112-22211---1111111111111113111121111332111111113222-2222222222222111121-1-11111112111111-2-------1111----1------------1111111111111---111----211121111111-1-12111111121-1224-2--1221111111112211122223-1---112221312232211111111111-111121112431111111211121122412211111-12111111111211233211111111111111111111111111111111121111112222222222222222222223222222112221121111113211331122111-1121212232133121221111121212333342333355241111111111111111111111223111111111322122222212222213313331-1232411-11123122212222222222-222223222222222222223212111222222242212422112222222111111111111111112-----11111152111112111111111111111111222133332111221111111111111111121111111112111222222233211111133111122--------3---1-1------1--------------111111111121-- 46-1752-612222433744566556644466533343332335343234678733233122121112222222322222233323111374364A11111123231ADFvMMMDRCBECCCEDNFCRD**H3PHWJGDEIFDCDCEFGEGBCPFEDEQHKCADE35O676128N1431722213A64968T4388ED4 ---1---------------1-1-------------111-1----------------------------------------------------------------------------------------------------------------------------1---------- * c.50 Macro domain-like
[ 300] 11-2--2222322322-2222222321222432222222222222222333332231-1--3112-33 2322322222222223322-22222522222222222255222222311222212222--222323422222222222-221422222222212---111314332332--------------122233322223333432224222222222222222222222222322222222222223333322122222222222222222222222222222222112222222312222222222222222222-------1------------111212-------222------------------------223222122-24-22111111121232221---2-21-2322222222221222222--2122322211111423334222222222222222222-22422522222123332232223232642434222223322222222222223221111111111-211111111111111111222622797464445445333344663333-354776882266523344634355333222254243333322243222322222222222-434344333333324233222222223-1211111112222222222543435443333334333333333333-1-4422-11--143433344444444444-4434443444444334436343333434343434443434334332244442-333333333333111411111111124333111213-1111222244454444445255554455444544444212122121222223333333333444444444433442221332222-------------------------------------12--2-2222221 11--223-311-2246644755588754444444444444444454444655865456444444444434454455415544444444446464485554444656-53455833353654344457468e3-4393554354323353334667633525C23226623A25322223k22222534A5442253332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.83 Aconitase iron-sulfur domain
[ 301] --1----232523322-11422-51--12-32-----------------------------1-2---- --2361-2---2-18eP55-5I--GW55555AHGMH6JWo-Z4e2--3----552225--12B145F7635-111----1617-----------------2------12--------------------------66686---32-------------------------------------1-122---11----------------1--------22323--------1----------------------2------2-1--21--------------------------------------------------------12--2222222-2--3-------1---1----87-1----1--------2--733A-----2-MBD1-7C5BC633442443442-34B33E3A856-411112321432A6472859222427922222222511--823------------------------------67F9-7vaIgGEEGJH66888AAHG998959X8VTgne36896748A8P8JAQT456----31-------2-2922-121-----2-----12--3----111111-6---------------------------1---1-4-3--1------1----1-11-1--------------1-2-3--3443333333-2333333333233223221------111211111111111111222333321-----------------111111111-2313---------------44324242222155554767342455223------------------------------------------111111-------------------------------------------------- ----111-----11386B79777FFGA3323222226888699433446DAGLH88D446454-2---------2------222-2---57565473111214533-2B45352232422322325252AX3-6332232532432223233372632A23212222233E1222-11-----111--86---111112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.123 CoA-transferase family III (CaiB/BaiF)
[ 302] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111313-321222----12232--------------2----------------------------------------------------------------------------------------------------------------------------------------------1--------------1-1------------------------------------------1-----1----1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1121----------------------------------------------------------------------------------------------------------1 ----1-4-1-------------------------------------------------------1---------------------------------------------*******cYZUbob*rX*f***1*l*NdWd*YlzmMkZUNpQL*bkegf6A9GwD*121131181----------------------1- -------------1---------------------------------------------------------------------------------------------------------------------11------------------------------------------ * b.22 TNF-like
[ 303] -----------------------23221313122222222222323222-1--2------3---1--- 4342732233322-33233-332244333334333344644353424-2442343334--463282776732222222---1522222222222--222252244343222222222222222222222222232-22112224133333333333222233333255332222222222224321122221466666767365677735444366622121--33333284-11111111111111-11--42--22-2-2-222222-22-----1-1------------------------------------------245338876668252-5432222413--2222223221-25111123-23323433322222223342224333366665655666-33533535463299966B966868533353473255256333333334332243422-22222----2222222222222222223453435554999685633328756423323A4643432233343333544345122112141111111122113122422243322333222222222233333242222342222222222222222222211331332612454521121311113133135222121122222232223223333333333-33333333223331132133833244421222222222222224122222222322222222222222422222544424749111211111111112555453223241AABA3A58374862335---------131213322345333548767777522222224222244------------------------------------33-33222222332 ----863-42--11122212331976222222222243333231--111168E722112112-11--11-111-121111111121-12-212212111-2-1----3D4F3121522233122321327C3-33333322222-222232332322462222561-----44582333H4323343151563522216 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.21 Diaminopimelate epimerase-like
[ 304] 22222222222222222222222222222222222222222222222222222222222222222222 2222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222221222222222222222222222222222222222222222222222222222-222222222221122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 22222222A44234444442444443244344444435443444443444444434444322444466446446466666644444666454444444444546872262424224224F7562AM29-6O6-249-34C422426244-22-24422222A3424-428622235464*44446CAIN4962222224 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.141 Ribosomal protein L6
[ 305] 22232222222222222222222321121221233221111112222233233322222221112222 4443634444433466767-663366666666666676663635965545456665552254645576664111111111114111111131121111112121312231111111111111121111111111122122222223222222222222222222223222222322222322222221112222222222222222223222222222222222222222332222222222222222222222222222222222222222222222222222222222222222222222222222222222222222221121111111111111211111131212211334433333233221111141322222222222222322222222222222221212222222222222222222222222222222222222222222222222222122222122221111212222222122122222222222222222222222222222222222222222222222222322222222222222222212222222222221112222222222233322222255553221111111111111111111111111133222222222232222222222222222222212222311111133223333333333333-23333333333333333323333322232333333333333323333333321222222222222111211111222222322222222222222222122222222222222222222222232222222222222322222222122223233333222333322221112111111111111222222-222222222222222222211111111111313 1111112-5223123333433332322333343333133333333333333333333233213332221421323431332333333333333332423332253613A1743333143744448D294DZ6-56G2346444641434-4334255261-213421211111223654i33335F6593853311113 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * a.156 S13-like H2TH domain
[ 306] 11-11-11111111111311111111111311-111121111122222--1111------1111--12 12213232222231-1111-1211121111112111121111111321211-212222--1115212443212222221-2-12111122221211---1111111121111111111111111111111111212224311111222-11211--------11-2112-------------2122276-32555555555555555585666655523324247676664532222222222222132213342265253348566572321133442221111211111111111111111111111111122222222232-4E5555555453461112115123-2112211-22-2--13223-11123111111111111211112212111111111111-111111111321333433344445241112111111111--------1---12211111111111111111111111111111111111-111112111111111111111111-212111111111122111111211112----11-------11111111-11------11--121111111222212-111111222221-1-------11112112261-3111111111111211111111111---1112------45113523443333334-443543334343444344397932232343333333333333362133333--322122211222--11111111111111--111111111111111111111111113----1----111-----111111111-2114222222414411211111111111--12111111111111111-2----1-1112-11222111111---21321546551211 3322334-F64122322443323232222222222222222222222223333A2342433323333633333233323333333311223222232222222544-34367D88AC87C6884AE6R9c*D-ICN8796K77DC88787777IA876634885347653K35437555*55556ECUQ3BB1242221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.162 LDH C-terminal domain-like
[ 307] -------------------------------------------------------------------- 5691111111111112222-21112122222112121111222211211111111111111121222222111111111234243433334333333--333333335322222222222222234333333543244222224333413311122112111111143221211111211114444422322244444544344455413333254321134321111114522222222222222222222222133122223322332222212322222222222222222222223333333333333222222222246333333333333355333333634331462235222334432244123353544534444554644455745544444443435-3343443464433333444443334445554544443444444444443344444333222223344334433233333322232335334444675566564444445644444465656456554675444544544457455566444444444566557553334444445487866995599B996444444544443444444444434446343343443333333333334333333333342-3433431-33333433333333332333-33333333333333333333334333333333333333333333333333333333333333333113433333333354543333333333333333333333333345445443533444443333333333333333333333333334443333333333323452322332212222222111111-211122211111221122243333333334243 11------1-----------------------------------------------------------------------------------------------------------------------------------------------------1----2----------111118111113115-11-11---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.223 Triger factor/SurA peptide-binding domain-like
[ 308] 1112112222222222-2222114311111111111132121111111-2222423234432--1-11 3221622222322222222-22113222222322222232133422323232223232--2222333753212223322232133444444414332--4444444446111111111111111222222222225553322252334344353444444443333334444344444444434444332585ABBBA98A79A888856555588A777676644445456544444344466464333433-3-43-42-1432244222-21222311----111------------------------111--1111-373677745746575357643333441-51143555654335544432224243334-22-2535453344444433333333313133334333334-4444443444343343433333333333333333334433333------------1-11-1----11-----2344332222311121111111112211111112222221111121133123221233222241111111111122222222332222222-3333343432223332232222222222-1-------21242113334354344333333334334333333331--244411111133333333333333333-3333333333333333333333333333333333333333333333333333-33333333333311-4-----112143344444433233223223333333333444444445444444534442111111111333444444563443333333333333322334444441111111121-----1-111111-11111--11---23222424443224 ------1-211-11111111111121111111111111111111111111212111111111111111-1111111111111111111111111111111111111-25121111111-1111112-1-121-1121-1-11111-11111--1---11----11-----1--3-1122B1112134461241312222 ---1-1-1-----1-1-1-----11--1-------1-1-1--------1---------1--------1--------------------------------------1-1----1--------------11111-----1-------------------------------1---- * a.204 all-alpha NTP pyrophosphatases
[ 309] ------------------11111-------1-------------1-2--34-1----11-----1-5- -1--1----------------1--1--------------------11-----1-1--1------111--11----111--1------1------------------111--------------1---1-1----------111---111---11-----------2111------------------11---------------------11---------2-----------------------------------------------------------------------------------------------------1---------------11----2-3--2----111----1----1----1----------------------------------------------------1--111----------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-17-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1------- -----------1---------------11----111-------111-----1--------------------------------------------------------2C9WebPf*bXcbhml*tl*b**j-xe*YdZaqZU*cfagTYieP*aVUTQ985G586hiPeFFH43-11-----3-4A3A-C1-1----- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * e.1 Serpins
[ 310] ------------------111--1222223221111111111211111111111-----------122 1121333444422222222-2211222222223222425413323233222322232222232253552422111211121122222222221212-112232332334--------------122222222222222221113232222221122222222222211112222222222222222221-3245555555545555553344445553332322333333322333332333333333323311-11112-1-11--11-2-1112222222222211222222222222222222222222211222111123234111121122221224222112-22112233211111222112-11222333411111334332233343233343333226-44444433363-6445454354653325345565664452222222222213135----------111111111111111----23222345554455455633333332444434534433322335332222335423323323222222222222344224233432343332122222222443423232233322222322222222222222222233232232222222224222232332331113333------22442222222222222-2222222222222222222222442432222222222222222222222222-22222222222222-2111112222333322221221222222222222222222222222222222222222222212222231222222222222222222222222212332-222222----------1-------------------------12111111112223 11--113-52323335573755669753333333434443433333445877D86544434432222233322233313323333322226453543233424555-3F322422443242121932624Q2-3351424522211331121111112322123112111922313543X33363E9DA8D86652433 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.17 D-aminoacid aminotransferase-like PLP-dependent enzymes
[ 311] 112-1-------------------111---2-------------21---12-1-1111112------1 -12-12213332312--11-11--1211111-12221364-1-11121-111345331--11--216122-1---1---222-1-1--1112-2111--13112412122222222222222222----1---11-------------2---------1------1111--1-----1----122------145575655656666664255546653265422------41322222222222222322254-1-11-1111111112211------11111112---1111-11---1111111111111111111111--24145555555556-311544423-74-2---2112-1-3--112--323-133341111131953---2111-----------1-3364373512-232211132111142111--3-------21222222-11112-122411111111112111221111112122-224314----C8879B445532257545534533356512445113224212421111111351111111111--3--2-2--1223---2111---1-12212311-12332333331---------12-1---772322331325777755B777676B8697---1---------74444544554444444-5434544454545444445555663325645555555455555444354441-5444444444441111-----333311-232221211222211128888838223424454567826689333222222222214559454437566533333333333333---711111122222222321----1-1-1--------2------------------1-2 -------------1111111-------112111----------1------11111211----------------------------------1----------2-1--81AFMHHEB89869A9GI5D9Kx7-C8H598AAB7787899A793HBAB7958E2G812534C77B3-1117---222--21-42-IBEC- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.49 Proton glutamate symport protein
[ 312] 11-1111111111111-1111111311331321111111111125232123231-1-111-1----11 1532D33655423234433-3733473333349777EAEC27296I763334DA723622AB9284A6A7211112111--1422222653412222--252227AC36222222222222221111111111113781111151522433222332222222223324122222222222222311---123333335552343534222244333222353422222244322222222222222323342131111211132441121322131322221112112222222222211111111111112331112112111332222323233212222221122113211331111311111-1-22412122222222234553333333322222222223-44656655493245428A59864533132122222223111111111111113311111111111--1111-12---11-21231225222222223332242222224233332332534342233223333423342222232232222222222224341214111111111132312422165577711111111111-111111111111111113322322222223333223222332333232-2433322-22222222222222222222-2222322222223222222422222322222222222242223222222222222222222222222222222234334233322222222222222222334222222233334423323222332222222222233332223233433222323322232222212772244----------211111------21---1-1211111221222-2221524 1111111-311-333122234333333221212222221212222222222233332122222222221222222222222222222222422222223222233232414222222-----1111-2-5F2-225----1--11---1-1-21-12123--23231211211413322T2222262372543522133 ---1---------------1-1-------------111-1------------------------------------------------------------------------------------------------------------------------1---1-----1-1-- * c.71 Dihydrofolate reductase-like
[ 313] -----11----------------21--1111-1111121111122222122221-1-----222--11 2322222222222222222-2222222222222222222233222222222222222222322222222222222222212122222244542422-111212111111---------------2223222342222233444224222222222222322223222234222222222222221222233333333333333333333333333333333433333333432222222222222222222233-222322322222223222222222222222222222222222221222222222212222222222244233111222131354333333414113223244253233333334222222322222222222222222222233333333333-22222222322233333333333322322232222222322222222422222232222222222---------------222222222144444333333333333333333333333333424333222444324222422222222222222222222332322232232222222332222443422342322222222212111111122222223333332233322222222222222222222-1222222122233333333333333333-3333333333333333333333333333333333333333332333333333233333333333322223333322222233322222322222222322222222222322222322322222222222222222233333333333333442222222222222222333333111-1---1-1-------------------------22422444442332 11--223-311-3333332333333333333333333333333333333333333233333333333333333334424433333333335333373333331454-3C-5353143334333343342BQ3-4442223313432332333232432222424313323B32623223S2222242673223485443 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * c.24 Methylglyoxal synthase-like
[ 314] -------------------------------------------------------------------- -------------------------------------1----------------------------------------------------------------1------------------------------------------------------------------1-----------------------------------------------------1---2---1------------------1-1----------22------2------1--1----1----2-1--1-1-1--1---------11---2-1--------------1--3----------1--3------------------------------------1-----------------1--1--1---------------------------2-1-----------------2--------------------------------------2-1-------2----11-------1-3------------1--3---1----------11-----------------------------------------------------------------------------------1---------------------------------11-133111-13--51---711-241211-1---1-----21-1-2111---1---1-111--112-2-------------2---------------------------------------------4-----1----------------1---------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------*-ABC8BCC8687998NF6M8c*E3NDO7788B79A869966A56D9857931-45684944532321NXT*FGBbd****-**4b6465T -1-----------------------------------1---------------------------------------------------------1-----------------------------------------------211------------3-1---3---4------ * d.10 DNA-binding domain
[ 315] -------1-111111--------1---1----121---11111111111--1--------------22 1221411-----1-2----------3-------1111211-21122111221332123--2411112323-2222222---11-------1--1------1--11-1-2--------------121-11------11111----11-111-1--11--1---11-3--1-------------331----1--122222232122322211111122211111212222221-111111111111111111133231221111166112243422144333331123113333333333323223222322323331113333---211111111212----2222-1-11---1-11-1----1-211--1-2-2111------311113111-2--11111111111-1221231122--122-2212322311-1-11111111-1111111111331----------------------------------1-32--11-12222221222222322222222231112--331-----1-1-1--1--12-2---------------------1-11111-1-11-----11-122-1-1-----------------------112221--1--11-111----1111-1111-1--1----1--11132111212222222232-2222232222223222223544112212222222222222212222222231-311111111111------------------322212112-21--1111111----2-22222222-22221111111111111-2222-1111222221111111---1111---111111111111111--1------1-1121111111111-----------1--11-- 22--533-C53-343AA97534585962222222222222222221BA785658446111113212221142-214523411111---1843A23711115B622213C2MGLFJHFBB99DDBLHEMDe*F-JFO6DECEBCDD7DABACA5CDEAEJ546FNGABF79Q8FA2133--23198PXzy7eK42TMZa4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.19 Aquaporin-like
[ 316] ------21222222221211111----------------------11--1111--------222--11 2211432222221131111-12112211111222223233-22211142221343233113352332B6611111111----------11-1-1--1--1632252423------------------1-1----1-11-1-----111-111--111111111112111111-1111111-1-11--------------------------------------------------------------------111111111111111111111111111111111111111111111111111111111111--111---1------------------------------------------1-------1--42211111111-----------11111111111-11111111111-1111111111111112-1112121111--------11111-1-------------------------------122121111122222222222222122222222111111122211111111121111111-11111111111-1111-1-1----------111--1-1-331364-2--------------------1----11111212223313444433344443434434--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--141111122221111111111111111111122222211111111111111111111111111111-111-1111111111111113434433311111-1-221111-------------------------------------------------3 1111672-744-66454444444444444445433324442444444445446544454444575554455565755255544444333593436433335435663646RHHFKJIEDCCABCFDEICZ*J1JFRAD9BDAEJFBCDC9HGCKAFCBCBOYMPDOKfMYmGOFN3444P53264658B45C347CA83 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.98 Leukotriene A4 hydrolase N-terminal domain
[ 317] -------------------------------------------1---2--222--------------1 4371D22222212142222-22222222222222222433254311131531345423119813335944211111111112111111222222112--15222A342511111111111111133135111111111331113142222222222222222222722622222211322221111111312333333535935355313223133711153111111115113333333333333313311111111111113511111111111111111131133111111111111111111111111111111111111155333353313131551111114311221133511311111111111313111111111533131113711112222122221-33533333321152233313133135231212111112211111111121133121111211111111111111111111111111111111112333433457773343777539335513311115313313111551111211211111111113112134121134311111333111513231255111221111111111111111111111113421222211233333433333333333331-1111111111162554445667567455-655555455564545555423343244555555555555555545555555112222222222221111333332222326172222222222-2222545652311132111111111111111332222222221111222222213222222222443222211121111111111111111111111-1111111---11111111111111111111311 112233--321-4362332644485744444333444555555444454433332343444444444434414443434444444444336435552444163542-45-44222222211222442212E2-222112221222222212222122222-2232-2222-4423143443424526483661176654 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.150 4'-phosphopantetheinyl transferase
[ 318] ------------------------------2------------------------------111---- 343-2---------11111-11111111111111111111111151-211111211111112112-122211111111----123444HGUG6ODH1--22222221211111111111111113332342353411111---21831122122221111111113214111111111111142111111311333333333344344221112334111111111111112-1111111111111111211111211211111111111211112321111111111111111111111-111111111111111111111211111111111111211111111-1111111111114211111112122132644333333536344443433633333333334-2252463443426557333444333334334335333346666666658645A431233333311113333133333333333333464345444443643544444469434434456567833865444653353533364644543334333333438454454574647862545A7554C4434455411-1111111111111111112111974651455335455555554555445444441-3534431233344444544444454344-44455544454544444446444444444444444444454444444444451544444444444--8445555333344443333333333333333333333333375555554565555545551111111113644444444445444444544444444433G-11----111111111117DF14--13112111112111111112111111112232 2-------1---------------------------------------------------------------------------------------------------1--------1------------------1-1------------------------1------2----1111-1111----1---1-2---- -------1-------------------1--------------------------------------------------------------------------------------------------1------------------------------------------------ * a.55 IHF-like DNA-binding proteins
[ 319] -------------------------------------------------------------------- 11----------------------------------------------------------------------------------------------------------1------------------------1-------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1111111111---111-1----11-1111------111111111-11111111111111111111111--111-----------1111111111121111---111------------------------1111-----------------------------11------1---1-11111-111111111111------1------111111-1111111-11-111111111111111111111111111111111111111111111111111--111111111111---1---------1----111111111111---11111111111-11111111111111111----------11111111111111--------------111--------------------------------------------------------- 4421456-5---AAG87778948A98977888899977455767677878787848889888423445-14433255-556334236779AA7AA8E89A8766C9-815MMTLUUOHIEFIKIcTEeG**Z1eMoGCCGOBKQJEKGAFVDBUDMMJG7LAGCCDANHCfCNBA1593B971B9LADS7LA356776- -----------------------------------------------------------------1--1---------------------------------------------------------------------------------------------------------- * a.159 Another 3-helical bundle
[ 320] 11-121----------12------2--2-43-------------1-----332-1111--2---1--- 229-9211222121---11-11--1111111-1----122132D357-6651AB9-----112-H148911A4443CA1----1----GGlV-B-----3L-82P2L-D----------------1----1----4AA69---3----11-------------2-1--11-1----------42-1154-338111111---11-1--94AA3811-344-214222222-c11111111111111111111223-21-32-211--1211127-1121111111344233223322231111111111111222111222361-B8-------3-3E2--1212D-81-235-1-----22---433B--3--96332-----312-11--1-11---------------2--1-3111-1112322332112-7--1---1---1----------334---1------------------------------16344-----222223-2222--142222-3-2---------111-----------------------------1-----3--------------1--------1H1----------------------------114--G-16-1----6---6666----6---------------2213-45111-1-2-2--111122-1111-1------555552-111111111111111113--11111--122222222222--1-------------12111111-----1--11111121---1G---1-1-1----1-4432111-1111-----11111-------76666555------11-2--11---------------2-----------1-1-------3-3262446-R23 --1111E-PB-----KFMNKORGSGQV55222211111111111119648PVeoQRSOE89811211131--2-111111111111112416F7L-121-146-12-6V2223222111--11164121371-211-11-1111--111-12-11111711121-241113232119B--22278MGEDMC936F7DDG ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.67 5-bladed beta-propeller
[ 321] 64425B678CAC863751653564B56ACE69212342211222232232544142334331115-22 118-43-21113--2129B-B1--11995AB-2--14335156633-1-2-22----1----33425323111113411253--141-1-2112------2-211-33---------------2214488118-4---2111-2-A6759622133333-11891L59B32--1111--311-221111-111222223212222222-1--1111223111311-----12----------------------11--1-----1--11-21111-1--1--------11-31111111------11-----------1---4131-----------232-------13--1212238221222322221--111A451-7415345387442835A22222222226-753446C8568-77553589FC4B5A--24393732---3233333354A1126A------------1-44-1411-11------2544-123-47455375111155222222318664376--24624563B95323--921-1--12--1--B22933-144259316232313357328181111-22111111------11111111121---3222666-322224444434352353632433---A21A------43CC48438833533852933897789BB4444344488869AK85459876576897998866676553-455455445445--911111111--1223244424252313543331311321--A114613444533241442---------15223657652235342332441224141--5-2222-1--------6-----------1---------------1-1--------1-- ----------------------------------------------------------------------------------------------------------------5--------------------------------------------------1-----1----------------------------- --------------1--------------------------------------1-----2------------------------------------------------------------------------------------------------------------------- * a.43 Ribbon-helix-helix
[ 322] 11111122222222221221122133332333-----------1112112322-11121223111122 2432412111111114422-23223422222346464244333332221111122321112242435453223333212322511111332213221--221333112211111111111111111-131211222222211142212111122111111111111112111111111111124422112-1122222222222222221111122211122223333332411111111111111111111232123122232222331222322222222222222222222222222222222222222222222222212223222222212142222111222233221222111221111111132313555433333635442334232333332333334-5565526544424444554675445323323423424323333333344442333111111111111111111111111111112445343332456656542333557655553456566541245433455335554343532343233333343344411213211--1111-222121122446465122333333333323222222222323322232222222132222222223222222221-12212-11-1122111222222222222-22222122222222222222222211122222222222322222222112211112112222111111212111222222222222222222211112222121222221111111131111122121111111112111222222222223244444333111111111122222222222221211111-111111111111111111111111111112343 1111333-52111122222222222213322222222222222233222223222222222122211112112121111112223312222322392222233321114284643343433242873628Q4-5482332433443241-34233422344544432212521321222F11122A1-22133222226 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.18 Uracil-DNA glycosylase-like
[ 323] 1111111111111111311111142222222425122343332322222AGCD122112111111-22 3252322222213133333-53223333333333333333233322223222233222--3331433343211111111--3221321443322---11-212323222--------11-----32232233243323222223133433333333333333333334442333222323323333333-232444444442444444334432444333322122222234111111111111111211111-1-22-----1111221---1-222---111122222222222222-------------2112211111362333333333232333321113241133232GO6424322A33332-33132224-----224333223332422222222223143233233433-4443334333443222344345445432222222222222322-----------------------------12323122222344443333443333444434433355323555433533344333333222321111111222333157422222222221232222222333335322111-11111-11-1111112112211334322322233333434333333344344--1233311-11144443434344444444-4444444444444444444444442135454555555545455443444442-43244443444411-4-----122233433111122-11111-11333332322232333233333333333331--11111-344443333344444222222222211112321222222--------1-1----1-111211111111111111131433434441522 ----112-21--11211-1-----1-----111-------------11111111---1111--11----1----1------1111-------1---1111---221-221323222-211-22233243FT2-338121321122-3321521322122--61623------12-1122Q2223131241224242321 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.46 Methionine synthase domain-like
[ 324] ------------------------22222222-----------1111111111--------------- 323-------------------------------------------------------------------------------12122144331322311332228352311111111111111122222221222222221113322222222222222222222322221222222222222212222122233333233333333333222233322233232222223322222222222222222222322222223332222222222212222222222222122222222222222222222222222222222224454443544624353443444443222222233322323222332222221111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111--111111-11111111111211111111111222111311112222222221222222222333332111-1--------1111111111-12-331111111111111111111111111111111-1211211-11111111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--11111111111211111111111111-111111111111111111111111-1111111111111111111111111111111111111111111111--1111111122222212212-------------------------33233222221112 3322667-D552655666746666556666666666866666677655665566667666664534642666444663676666664446A6676656666667662994C6846585575656673B3**8-86A6655645635575664577764548F46564344734867477e76569966C66J4656554 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * a.113 DNA repair protein MutS, domain III
[ 325] 22435511111111115243233777775685333666666666666655777554444541324122 221--111221-1-11111-11--1111111111111111-111----------------11--1-1-----------3333334444222212222--22222232221111111111111112222222223223244111224443444433311111233434443-111---1-11-3333333133444444464444644553554644445454444444445444444444444444444544444455454445555554544444444444444444444443444444444444444544454444444435465555555555544555555555443555444343434333453354244111111111111111111111111111111111-11112111211111111111111111111222222222211111111111111111111111111111111111111111111111111111111222222122223312222222222222111111112222223121112111121111111112112147665555555553455455655223241345222222222222433223343234112211313112312222222222222242531-11112------21112111111111111-11111111111111111111111111111111111111111111111111111111111111111--11111111111112111111111111-1111111111111111111112211111111111111111111333344444343461111111111111111231111112222222254333322-331332233321123411133344444541332 1-----1-3112--2233311111111111111111111-11111122112222221-1222-111111111111111111111111112413111111132311113812-1111123221214326-BI2-424222-1222212212222521223-31121111112--22--1472211-1--13122421213 ------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------1---- * c.107 DHH phosphoesterases
[ 326] ----------------1---------------1-----1111121151------1111111------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111112232553222222222233123334222222222222-----11122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222222222222222222112222122222222222222-21--1111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111--111111111111111-111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111311111-111111111111111111122222222221121 ----941-8462DG787C85999BAA8888888989777777778897786876779767773553332444555432334455756555EA7CDB75785B3666-268A6468595455455785D4Dl9295F45557557255572965D37555288555i8777C576F2741922276EHJI9HK3-44671 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------21--- * a.149 RNase III domain-like
[ 327] -----------------------1--------1-111111111-1-11111111-------------- -213F3132231--35422-251158222224855566B8341-132--222734--3--6532656DLA5-------5---5-------1-------------2-111-----------------------------1----1-1111221111111111111111211111111111111432-----1265555566625555657655575553453547899A98112333333333333322112286425A22948AA22965394342321114333322444444444443333333333333356221555412-38222222232526--2333--11-2----6712--3--112111-3-1-533211111--345--11213155555554558---5--5-336--A6655657679A311312553125456--------2221--21-------------------------------112-6FE999999995877888BB788956B8EFGF922776332124247764322222531111111111222-32---11--1--2------1-11----1----------------------------22542231225242222122222222222222----111------65742637776755588-7778743878756667665797562217467676777677777565456664-444354444455--121111111111154611112------1111555552113312887866894655514561111111112333233333344331133333333----1111-------------------------1-----------------23---5-1-1--- --------------1----------------------------------------------------------------------------1-----------------------------------------------------------------------1------8-----222C22213---1-----1111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.190 Chorismate lyase-like
[ 328] --------------------1--1----1--1------111111---3-----1------------1- 112-2--32221---11----1---------------1--223341--2---1131----221-4121431----1------3----------------11-111-1-1---------------1----------32266---42642133211--------22115533------------52512----2222222222222222223222222213243131111115212222221222222112222111---1-11111-------22-----------2------1-------------------1---------25214222222212125111211223-342-1111234-2211-112-11-122112-----1-2222112222111111111111-22222222111-11-11111111111-2-2432222212-------------11---------------------------------21------1----------11-1-------2-133---22-21--------2---------1111111---2--1--------------121-111-211115611--1-1-----------------1-1-------11---1----------------------2-----------------------------------------------------------------------------------------------------1111--4-----------------111111----1-11111121111121222---------1---1------1-----1-1---1--------422----111111111-------------------------------------11-1 1-55GD4-1---CB245442222322122-111-1-12222222224433564644611333235333152252223132255533---24152481123-725121-36*EFAAGLCCE9FBBOIBLAf*G-KEXADECIBBECBDFCAE98IBEBJJeXCONKPAZLb9Lf*81EY1----E-AQHM2MC1IWSTc1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.111 PR-1-like
[ 329] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---1-----21-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-------------------------------------------------------------------------------------------------------sYpZdfdMCKNLYLyYHaG**c-dWmIJHIUJMjUDOPSVWLEfOOMgPCF9I*m*I*8Fq**O--11-----2--------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.8 BPTI-like
[ 330] -------------------------------------------11--1-1------------------ 2252722222222253333-342235333333355556B82733432221123632321174225489862222222222223324344323-2223--232225232222222222222222222222222222444343324244344442233333333333654563333344333343332233112133333333233333311111133322211222222221122222212222222222222212112111112211222221112221111111122111111111111111111111111211111111121133222222223212332222222321222222212211111112311332222422222233342222222222222222223-24224332232233332332222232222234323322222222222322222222222222222--11111111111113132-2223233324734345556666566888837634555322323323223222422222322322222222222233222222232232222111122131224246222112122222222222222222222223332332222322222232222222222331-22222------24233232333244443-3123223325343222223433336532433432333333332422222232-377777747776112222222222222333111121111111111333333322242666633435433434331111111112434333333344332232422445222222223333331111---133--------------------------22233322332222 33--111-611111111111111111111-11111111111111111111111111111111121111111111111-1111-111111121111111111111221171------------------------------------------------1----------------2584k22244CAAM1HA2442114 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.174 Double Clp-N motif
[ 331] 22-1121111111111-1--2--1-11-----1--11------1-12-1112111-11111111---- 32222-11111-3--1111-11--211111112111-1111-1--------1-----------2---121-2222222112--221--222212-1---14121412-2---------------111111111111-------1-232522211332222331321325-121111121111111231-11--111111----111---1------1------1-1111--2--------------------3211121221411442132132122233333332221111111111133333333333331223332223-2-11-------2-2-2111343-1111-11-----1--11-1---1111--1111------22122--22--1-22222221223-43334533131-422321-143-1221-1111----1112222222244332--1-------------------------------23-21-1125555555544355645555248542313-1544212--21-12111-----222221222---1113232131211311111-1-11-22222242-11---------------------3323311-111112111111111111111111111--112--------311-2313333333333-3333333333333333333444-1--1333233333333332233323333--222221212222---1-----222211111111211-11-1---11111111----1-------2-1-1--1-1112111111-122111111111112213233223----1111221122--------1-1-------------------------1-----1----321 ----667-633-23524433333533333233333333233233333333443433333333323212-31-32323-12133333-2235343332222342222-6H9D9EAJDI9999AFCOL9HBg*E1GDP9AB8EAC9489885A76ID999859B9A6749485AB962567K54599C8CA48793DBCA6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.20 Clc chloride channel
[ 332] -------------------------------------------------------------------- -451722322222256655-5E44565555549699547713341-21---11121-1--3233336C77111111332132-112232211-2-----1512-62223--------------1111223111-422222---122133111--11343655-2213343-2-----2-----------13123343434434444442211234442221---------32--------------------14222232321442222223--1---111-1-1-------------------------------------24157443444454523332221-3311123121145323-21---1-12121411522222ADKGECABEEFED8899789898C-JMIKPGHHDJ12CDDAHGHGGHGEAC-11D4B9999666--------1----111------------------------------54411-----1-----------------------1111----12-11112111-1131222251111111342232C2211121121111166626372544-42C773111-1111111111111111-12D555531532---333333334544334443441-33432------65444536666666666-66666666666676666676664432376667676677575674656666511323233333333-11288887888881531111111-1111111122222222444133333333324234222---------2111433333333332212122111------31--------------------------------------------111111114181 ----1--------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.160 L,D-transpeptidase catalytic domain-like
[ 333] 11------1111111---111---2111--11----------------------------1111---- 1212311111112131122-211122222221333325533333233322224463332233323273333-----------4-----111--1--2113334333323222222222222221---1----11-57733---33111111111111111111111111111111111111144444---224444444443443444474464444466344322222241222222222222222344422-1-22-1---111111111111111222222223322222-222222222222222222322222222211---2221212-2--222---------2--------------1121--23-2422222222224223222222255555533444-225225232422233232533354233234242222232222222222221222211122222211122222222222222222236931232233443343333322243333253333333233332222222444322211112322222222223222-2-2----------3231334--323333-21------------------------113223323343334333333333333333431-1432212111132222222222233322-222223322223222222324422222222222222222222222222222212222222222222224222233333223232222222222222224444424222324444333333333222222222222211223222223323333333332222222111-222221----------111111---2-1-----131-11-------------1323 ----333-322-3333332343323333333233333322232333233433433332233332222222222222222222222222233333434333443543-25362433353122223542417U3-43923-1333533232333451742338B2423-111A43334423e3213468B93754332223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.9 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
[ 334] 1111111---------12111111111--11-111111111111111111111111111111111--- 33614---------24311-1211331111122324427113-2222-111-224---11-153413432-1111-111-1-2222221132-1------2-122-2-2---------------111132113122223311122-12-222--1111112221-11112-2-----21---11-2222-322224242332353335334423333122-31122222216--------------------2-1-12-1---33114511112----1211111-11222232222221111111111111111---111151-14111111111123--112-311--111111211112122111521-1133112-----31679-112-23-22222221223-11511415-64-7113326433674124145231345122222222263312122--------11--1-11-11111-111-11-1251-222245677753333255774444249275475-3553212--3-6368112-224---------11-131-111-111111111-1111111111111231111111-1---1111111111211-2222132112-33-----1-1-1111----1-2----1-2------63441336446666566-46465666564765555559A74521-6466666666656565445444554-355555546666-------------2222622221311312333211-11-3---42333336651363-1343-11111111-1--1111111111211313111121111--11331111--------2--------1--11--111--1111---1121122222-61- ----221-21--1116767533465444465453233333333333533338D512512222232123121141221111233343224--272211121422222-182B7775874441445B94B4QhD-C7954547435354444544B5444624133232739668541-11-1111211147151311115 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.74 AraD/HMP-PK domain-like
[ 335] 33333333333333334444444333333333333333333333333333333333233333333333 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111-1111111111111111111111-11111111121111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 44335443D7634443444454444344444444544544444444444444444444444443444424433444643442442277749444444344454A9F4454867444342D8473aQ3Z5e*J-CGs2255d43M42335872382644554545453849455535434b44434GBFO4763455543 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.12 Ribosomal proteins S24e, L23 and L15e
[ 336] 21---1------------1-3-3--22-2-2-----6----------------3242-6-2------- ----241222415112211-12221211111122122222121112-221111241-11111264223321211152241111--111-------------------------------------------------------1-------------------11-12---------------11----3158999999676998988C9CCBAA7645524AB366737235AAAAAAAAAAAAAA66689AB11761272BHF117B436543434666655555566666566656555554555455557744277751117ICCCEDCE9B81G223797222513231111121111114321-26---244---------------------------------1--1--------------------------------------------------------------------------------1--------222232222222222222222322--2--1--1-------1----------5----------------------------------------------------------------------1--88B2------61111112-111111--111------111-1119E962E5777889A988-7778989889798887887DECDC6664644454454444444976488772-A44334443444--1-11111---------111362-----2--5------------22222423-------------------56665555556744-----------------9------44244444--2111-C-42837332334872332221111112112---- -----4--------1--11--------JHK-46--------------U--------------F-8-3---522---F-----------4--------1--1----8--------------------------------------------------------22-------------2------231-B-12------- ----------------1-----------------------------------------------------------------------------1-------1------------------------------------------------------------------------ * d.95 Homing endonuclease-like
[ 337] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------HbYQ*VfbLMQZXc**Q*T**t9*g*JTSQfUf*lGfQMI*GK*RpPZe9O*-7999---p--6------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.23 TB module/8-cys domain
[ 338] 11-1--1111111111-122222143333333111111111111111111111111--1--111--11 1112433333343354445-4333444444443333445525253232343333333322333344645441111211-11-32222233331311-111333323332--------------233333333333222221113253533332233333333333245423333333333332222221-334444444443444444224434444233443333333322233333233333333332331----------21-------12-33311111112112222222222211111111111112--222----22-12----------111111111-1-121112443111--222112-112222222-----222112221121133233333332-22222222222-2222222222222222211322222222222222212212123-----------------------------2222222222223333342222222233332342222222222222222122233223222242222222211122313223122222222-122222222222245222122-22222122222222222222224432232222333333333333333333331-12232-1---164443424455455544-4444445455455444444445545534444444444444444444433342-4555554454542212221122222223333332332333332333334323222326766332422222233222222222223435444444334433222222223222222-222222--------------------------------------1--1-1112333 11----1-1---2222222233345352222222223344434222322223233322233322222212222222212222222222223222222222232222-14-------------------------------------------------3--------------1-3233M3335254682731352222 --1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.161 ADC synthase
[ 339] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111*qd-735-23434443344444444344444434343344443444444432445444434223132232332-2233234333327441552444312341-UABtJVPTRWNOLHMNLTRJzLx*R1UQ*KONNRMLNS6NOJ5NKKyLNLNMHx*ESK43F8EK54RY1223A2213332554231145666 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.64 Mannose 6-phosphate receptor domain
[ 340] 223-1-788888988A--21111-2---1--------------------------------1------ 15C24---------1--11-12--5711111433331369331411---11-2121----1-C-54C655--------1---42--2-------------1-3A8-8----------------------------35533----A-1-111---------------1-2--------------23-------1-----1---------12---1----21-----------1--------------------1----------------------------------------------------------------------64-24444344434-5------31-21-112-312342-3-4-------8--7553-----46OQR514696D71211-11-111-DCKBCJFI9A4-722411A5418FC745-BA1555588977777777B5532721------------------------------4672-79748FKKKKF33331KKHH333313E8KIEL5-488875711E292G2242-2222-----------2321-3-4111121111--1115211322-266-5-------------------------222--6223-7-223333352222222--2-2----1---------1--2--3332322232-3333212323323332331------------------------81--1112-----------------------------521---------------1112111-2171999943D6686774423---------2---4----------1123233----------2--------------11---------------------------2322-----15-- ----111-----11-21222121121222233211111111112221311122211111111-----------1-----------------11-------1-1----277F23234D22352635D5544B2-32452235236232324E43A2624626O2A83C69D8M384-23-A---3459D82A61131112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.133 Molybdenum cofactor-binding domain
[ 341] -------------------------------------------------------------------- 2222222222222222222-222222222222222222222222222222222222222223222222222222222222222222223332221222223222322221222222222112231122222222222222222322222222112222222222232222222222222222221222222221222222222222222222222222222223222222222222222221222222222212222222222222222222222222122222222222222222222222222222222222222222222223222222222222222222222222222222222222222222222223222222222222233222222222222222212212222222222222222222232222222222222222222222222222122222224322222213222222222222212222222222222222222212222222222222232222222222322222321122222222122222222222222223322222222222234344443433334332222222222222222222222222221222223222222222222222222122223122222212222222222122333323323-22233333332332323332223322332332232222333331323231222222222212222222212122333322211222222221222222222222222222232333212122221222222222222122212222222221222222222222222223333222222222212222221-111-11111111111111122222222322332 43--221-511-1122221122222112222212122212221223122221222121121222222222212221111122222222123222221222112112-1724533355433245432241EK3-437322333333233323234433332111121-134311225274M33323456929D4342323 --------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.38 Release factor
[ 342] -----------------------11111-111-----------------1------------------ 2222322222222222222-22222222222222222224222332222222222222222222222223233332222222222222332325332--24323333232222222222222243333333333344444---4233343333333333333333333333333333333332222245354444647466456644554444465554556564444444444444444444444444444433344343333333444333334444444444444444444444444444444444444433444333447454333333333333444333545333332344436247326655342341222222222222222222222222222222222-222222222222222222222222222222222222222222222222221222222------22222222222222222222222222233333333333333333333333333333333333333333333333333333333333333333333333224223343444432333332323333333221-11-1-1111---------1--11332222222222222222222333322223222-22223-2-21222222222222222222-222222222222222222222222223222222222222222222222222222222222222222232222222222223232222222222222222222222111222222222222222222222222222223332222223223333333333333333222333222222222222231----1-1-1-111---11111-11146232433433333 -------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------1129111114112-12------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.98 MurF and HprK N-domain-like
[ 343] -------------------------------------------------------------------- 1212111111111111111-111111111111111111113224211111111111111111211111311111121111112111111111111111-1211111121111111111111111222222222222222211113A5656663255555555554655554444444444443332211121111111111111111111111111111111111111112311111111111111111111111111111111111111111111111111111111111111111111111111111111111111111113434333334324213333222331124332243222222133331111114111311111212344211131411111111112-35112122111121111333322112112212131111111111111311113111111111111111111111111111111111111111111322322122224424222212334131211531131211223111111211111111111222211211112121211111333122332333334232222222222222222222222233111111313111111111111111111111111-131111111111111111111-111111-11111211111111111111111111111111111111111111211111111111111111111111111111111121211111111112-11111111111111121111111121112131111121111111111111111111111111111111111111111111111111111111146C51-111111111111111111111311111112211 3311443-F66-2221222222222222222222222222222222222222323222222233332313333333323433333322233222222222221444-39387476574343324653634U4-5573434434522344355354534434433355434536336AAB*CCBBAOCLQ2KF6622227 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.269 FtsH protease domain-like
[ 344] ---1111111111111111111111--1111121--------1-1121--1111121---1111--11 3431433233333332233-321142333332222243433347222321213332231133634334443222232211133323223334-2111--232324232211111112121111444254433434222443342336455424333434223422333452212221222131123311211211212222222323223222222222232211111112222222222221122222222212122122122222222232221223221111111111111111111111111111111111331111212111222222213111221111111122111222522121111111131322333422222222252332222233333333334-22322222332-3333333343333233333334333333333333322222332111111111111--11-11------1-11-353323333355555435455443455552445333342233323334344333331222234222222233233313433233264223222233324322324423222222222221111111112232232222352332222322222222222222232--23222------23323222333223322-3222332222322222222333223432212222222222222322322231-222222222222--12111113322324333332221111132223333323222324444444344443433421111221122222222222222233333333332222--22332222111111-111--------------------------32223222222322 11--111-842---2121121112321111111111111111111111111324121111111111-11111111-1111111111---111211-11111-1111-186------------------------------------------------1----21--------412444l33332BBJN1C6222---1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.129 MCP/YpsA-like
[ 345] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------1------------------------------------1----------------------------------------------------------BMMPRgcfcWcVph**e*f***-*m*SaUXyWZ*yJXZVNsLLcNWOJP------1--------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.26 4-helical cytokines
[ 346] -------------------------------------------------------------------- 3363------------------------------------3---3---6--2-2--------3-3------------------33333-------------------4------------------------------------3---------------------------------------------333224246444444434343374447544435333333333------------------------------------------------------------------------------------------34464888668677763446---556--37643353534334333334--33788953----33IAE553AI69E33333333333-A7D8949C44427669986AAA665-8473336666372--------2225-357-------------------------------1433344434444748444444444448474544445--743444544--435654533483-------334153844-545758A669453653336344-4--3-4445-6555443444444444653---65-746446555A66474744484378885---35431--11174347333334333333-3623633333336133223---43334432434344343434333311123335864686A7775---------3333--834-------------------------3944444443654345444---------5888777777BB7886644444448------I65677673333333355--------------------------6-34553455-7-- --------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1----2--------------4-----3---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.32 Phase 1 flagellin
[ 347] ----1-1123332111-------21111111111--------11212111332-11-1111-112-11 1221111111111132222-22112222222222221222111123211332222112112211111111111111111221422111222212112111111131122222222222222222111111111113333311124222333133111111111121322211111111111112122112112222222222222222233322222211222233333322233333333333332222323-312214-113322222222232223333222222222221222223333333333333222222222212223333333333322552222322122222-222221221233211123-1222222222232332223333322222222222-2232222223212222222222223222222233332222222222223312222111111111111111111111111111112222221111111111112222111122222212211211111121122122212112112111111111111132225524341242111111121215322322144211111111111111111112112322333211222232222222222222224222111131211111144433424444444444-44444444444444444444544444444444444444444444444333421444444444444221122222222221113222323222222222111111112232222222222222232221111111111333533333324221111111111111111113333331111111131223322-3133222333232232111-1111121112322 3311221-511111311111111111111111111111-1111-111111111111111111111111112211122222111121111222122211111-133311622232231111111131121492-21611111114--11111113121111-111111111511213223T3233384771652211112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.224 SufE/NifU
[ 348] 111-2121212233142-1-1111211-11111111111111111211------2221122-----42 4421441111111111112-1211111121211315323313222112132132212111124311124311111211124132-2--3435-3111--112112111211111111111111111111111111333231-222F2451221112---11-31116732------------45422222722222222422222222232222222222222253333363233333333333333222227222222252222332222111133312221311111111121211132222233152121111111111253232222222324533222111452113942112212321132521--2236116112152373A777432122222222222B-37625B25B761677EC66979663F141955B78B452333333332533164111-11111111111111121111113-3514BB4112119535555A222299582322353982649119772A5876A53522751123111211111232714146213112223321112511213554331-2111111111111111111111111123122141111111123421111111211111--14123------2--13412453233651-413451211243144244164631-2322111211213523146121--11--24441433451----133313242232211----1--2--1-21-1122211111112455322921122143211111111115233222222222241315231114223--9144445422222222311--------------------------1--------2221 ------------11--------------------------------------1-----------------------------------------------1--------1-----12------------------------------------1-----------1-------11-111----1111-5-11--1223- --------------11------1---1-----1--------------------------------------------------------------1-----------1-------1---1-1-----1------------------1---1-1---------------------- * d.268 ParB/Sulfiredoxin
[ 349] --1--1----------11-----232232222374222222222226223887312-2222-222232 121-922522233232222-22112222222122223222322261242111221322113324523865211111112132411111111111111-11212112111---------------11111111111111111115764683333455333333333567744334444344444431111-25433333333333333374443433377524111111115311111111111111-11111111111111111111111111111111111111111111111111111111111111111211111111144456555555555543553555234114129488868654563334-111-332212222246A55J534665433333133334-76C77A89393124343334433454131472454443111111111133-219511111111111111111111111111111-22331121128995B65222266A933332256E343211331111113111211112111111111111124B3111111121121111111111111111311112111111111111-111111111111111213151131115315111111211112111-1511111111111111111111111111-1111111111111111111111111111111111111111111111111111-1111111111111111111111111111241111111111111111111111222111111111111111111111312213111111111111111111111111111111111111111111111111111---1----1--------1-------1311111111-3-1 --11--1----1111---------------------------------------------------------------------------------------------111885A453221332551838W42529231332332-33215224226331-1211118122112--354B243432223----1-1--1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.41 PRC-barrel domain
[ 350] 2211323222222222--1----1422516861113323333342231-656511212232222-212 223-1221-1211121122-22--2322222232221222132313111---1111-1--1111112231-11111111111221211113211112--2518355253--------------142-11222124-----111119DA57632222132442663567541311111311111122211-214222222221222222221133222111112211111111111111111111111122211-111111111111111111--11111112111111111111111111111111111111111111111111-111111111212121123331311111111111121111111111111171224-1111312211111222111-1111--12-22222222332-4552664777673154553122228463333333333322112--------1111--11-------------152323222145555553322244553333335455556-144422333321341234431222111111111221235534233245111111222426311113713111211111112122222222242411331857638745444437644436266345--1631511111155343545555555555-55555555555555555554443322476667677777676675544545421533333333333112323223222225443333212111112111222222334521566545644555545663-111111-266642222254554222222222211111--1--111111111111111-------------------------1111111111112- --------211-------------------------------------------------------------------------------------------------2-----------------------------------------------------------------123226222656224-13--1---1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.34 Mechanosensitive channel protein MscS (YggB), transmembrane region
[ 351] 11111111111111111111111111111111111111111111111111111111111111111111 ----1-------------------------------------1---------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------1--------------------------------------------------------------------------------------1----1----------------------------1-----------1------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1--------------------------------1-------------------------------------------------------------------- 4523CF3-SCF84484466444464565555556666666666656445555554455555522222212332223334322222377736645665444454B9C26J5W9DCCEJHJGCFGBmXGVGs*T4TPbIIGFPFGLHCIJJBPDDiKJCCB669I8884E778DLB53EA7M76577BJDD6L897CGIH7 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.160 PAP/OAS1 substrate-binding domain
[ 352] ------------------------1--11-11---1-----1------11111-------------11 2212311111111111111-111111111111111111112222121111111111111122211221111-----------212111------------111112222--------------1---------3-11111---11233333211112223222222433322222222222311211---233444444553445445343333554333233422222273122222222222212422221-1-11-----1122111--------------------------------------------------------11-11---111-1---133-1---2--1-11---------------112222222222443442224444422222222222-22322322232212223332222245222222333322222222222133123341222222233222222222222222222222222322222222222222222225222222255222222222522222523222233222222222222222233121-1211112223----1-1---22222321-------------------------443343333333333333333333333333333--232333333344343434444444444-444444444444433443444444444444444444444444444434444334444444444443333222222222533333333333333333333333333333433333333333333433322222222223333333333343344444444444444443-----------------------------------------------------52-1 33--222-72212222222222222122223122232212222222332222221222221222222212322222222222222222212222222222222333-23234223211222223341234D3-435321221232222222332433232122211-224613322332S2223375561443342223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.124 HesB-like domain
[ 353] -------------------------------------------------------------------- 2222422222222243233-33114434444443334444222232332222222222224423424555223334222222212222222222222222222222222222222222222222222222222223333322212222222222222222222222221222222222222233222222223222222222222221223333212222122222222222122222222222221222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222-222221222222122222222212222122222222222222222222222222222222212222222222222222222122222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222333333321222212222222222222122222222221223222222222222222222222222222222332222222222222222222222222222222222222222212232333452323133-4333334333433332332333333333233333333333333332222-222332333323333222222221222222222333232322223223333333322222333333232222223332222222222322233333333332222222122222222222222222222222222222222-222222222222222222222222222222222 11--111-2---112111111111111111211111111111111121111111111112111111111111111111111111111111111111----121112-141--------1-----------1---------------------------2----1------1--313224J4423363341331221111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.325 L28p-like
[ 354] ----2--------2---------2-22--2--37238--722524221-696G-3-----22-2---5 221--227---4-8---22-24--1-22222-24242-2--543-6-44----222----2-2-4-2---1-----445337---2-4-DCD--3-----3343-622----------------2464A9--714422-51--4-7-59988--22------442-6964--2----------4-11----22-----33----2-----66-----5621---4-4--422-44446424544445-2322---4-3--44--286-7-7-2--2-21111143332866869698883333333333333-995637771-6--2222-42132-4-552-2---4-922D3--46--645222-222-244A2222-----242---5--2-2-3333333333------------32-----224---2-3-22-----4-44287888888---3----------------2-35-2--2-21----------24---2---2-----------3-21-22222-2--2-4-2222--428-C--C2622-235---4-62-5222-6H---8-3643--522A--C22-2-2-22-2245-424652448989B7773-2-AA--83B--2-24-86-A44-A-44-6--9-2--2E424-------2-6A-3222222224--22--244-222221-22-422-2432-22321-3242-2222-222-222-------5----232--1---------272222666332-646676A2-----43472-42-42-2--22-2-842-421-17-122-2442229252227-2254754448485--24----22--------6-5-2-5--5--BC22---4-4HA-5672-4-2------42- -------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1---------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.287 DNA methylase specificity domain
[ 355] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1---------1---11211111------11--------------------------------------------------------------------1------*6I356111111-2321419K3-4342221312421-21--12915133akJH********tlV--31-----3---2----1X----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * g.31 Invertebrate chitin-binding proteins
[ 356] --------------------------------2221-------------111-3-------------- 3433222212222222222-22222222222222222222332422222332333222222222333445222222222221222222222223222--23333333332222222222222223333333333322222---232222222222222222222222232222222222222232222222222222222222222222222232222342222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232322222222222322222223222322323322332323222222222-222322222223222222222222222222222-222222222222222222222222222322222322222222222222222232222--------222222222222222222123323233333333333333333333333333333333333333333333333333333333333343333333333334343332423332222322333333333231111111111111111111111111443333333333334444333444434334332-1333312-22233333333333333333-33333333333333333333333333333323333333333233333333332333333333333222322222333333332333333333333333333333333333333333334333333332222122223333333333333333332322333222222333333332223222222--------------------------23322222222333 -----------------------1-11----------------------1--------------11------11-------------------1---------1------3----------------------------------------------1-----3-----1---31---2------2--1--4--2---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.5 MurCD N-terminal domain
[ 357] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----2------111------------11---------------------1111-------------------------------------1---------------3--yz*mouZMHJDKVMtYFiO**n-kVxAKKGeOPbOARLIDUH9fQUQWbMKNqfZGGkKUYCJPG------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.135 Tetraspanin
[ 358] 11111122222222221122211133333322111111111112112111121122122222221222 2222311222211122244-41222334434222223232226413231---222121--4222234223211111111111211-1-1111-1--------1111111--------111111-2212121222211111---1112212211111232222111211112222222222222212211-211222223323223332212211332222112211111121122222222322223232214-212212---22222222232-222333333233333333333333333333333333333322233331211111111111111-11122211111111111111111-1111111--2-11111-----111222211111111111111111-11111211111-111111111111-11111111111111--------111-11111-------------111-111----1-1-11111-111111111111111111121111111122221111112-111112111111211111-------1211111---------------------1-222221------------------------1--22431211322222222222222222222222---1112------22112211112122211-1111112121111111112111111112222222222222222111111111-111111111111---111111222211111111111111111111-------122111111111111111111121111111121113222222232211111111111111--1-1111111111111111-----------1---------1---------1-11111-- 42235322B442234444433434343333343554344443333344343333333432214243333334243332533444332433244333444433333523948545349544454486594Tg7-I694546655592447353342586653348442445133545555J4453497A94864349645 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * d.74 DCoH-like
[ 359] ---1--1111111111-1-1-1131--112111121222233122212113321-------121--22 332121-222211122211-13--2311111132222333121111--1112233112--111-1-121211111111--1-111212--111-------2-1114111---------------2312122212211-11111315122113112211131133213323111111112111211111--211--1-1111-111111112211111-11111111111113-11111111111111-111111111111-1-111122-1-1111111111----11---------------------------111----11-13------------22------1-11111111411---1111-2---1131111-----123221-12211211111111111-22121121114-1111111111111111212111112241111111122211212-----------------------------422111111-12222222111122221111112222222-122152-1123222123223231311111111-1242-3231232122112-223222233222312111--1-----1----------2122233132122212131222222222211111112----112------11112111111111111-1111111111111111111111111111111111111111111111111111-111111111111-------------43213------------11-22222131111222222223323223222---------41112-11111222211111111111111113-331122---------------------------------222-11--1-11111-- ----545-----11243534333344411111111122222221115322354433322444663232223143333244233433233242343A2221222445-5S6N7A88A5565444647384S*8-G8F235384463344544219464455AI3C7C3223576I528A5*43464D9CW5748675789 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.44 Ammonium transporter
[ 360] -------------------------------------------------------------------- 7PG--------------------------------------------------------------------------------2321367E9-534---3545344966--------------122232222354-----------12322123--------31151111-------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------2-84-7354-111186576755B95BE22222222222-3353324333513222322123224354823222222219999999974464252111-------1111111-111-1111-1115654233333456674844444453444434B8944432343365544533533496775644111111133444994222423623663133344465686B7PH442243243222123221222263-22BB65246A937526676665656444579437--13334------32242322343243322-222423523433322222223377446222221222222222254522223215333333333332228-111111116352333311212222322255645663437B6666688A4343459A9-11111111234443333345344FI99A9899B6666115-773333----------------------------------------------AQ24 --------------------------------------------------------------------------------------------------------------------------------111---------------------------1----1------------------------3-----3---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.212 TolA/TonB C-terminal domain
[ 361] ---------------------------------------------------1---------------- 3331222222212122222-22112222221122222222222221111111121111112221211222112221111112122343111111111111111111111222222222222222111111111112222222221222122232222222222222222222222222222222222222111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121213333213131112221111221-2111233221322212221211122222211111232222222222222222222222-22222222222122222222222223222222222222222222222222222221111111111111111111111111111112232233333333333333333333333333333333323333333333333333343333333333333223343334444643444441444444444333324242222111111111111111122122443333333333333333444333332443442-2333311211133323333333333333-3333333333333333333333333333333333333333333333333333133333333333311232222233334333333333323332333333333333333333333333333333333111111111333333333333333333333333322223331332233111111112211111---------------------11111111112211 1111222-3-111111111111111111111111211111111111111112111111111111111112111111111111111122211211111111-2211211111121122111211152212461-1111211211111111-1121111131111111-111311211222L2223323351762242221 ------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------ * a.173 Poly A polymerase C-terminal region-like
[ 362] 221111222212222312111111-1211111111111111112113221321111111122224112 123-11------1-52222-22--2422222232222244132121121222211111--54324264591--------4A4---11111131144---2322211321---------------1111111111111122---122223332-122------11221113------1-----111-------1-----43-1--154-212211114---22-113331121-111111112111122211-3-3----3-----11--313-112-1111111111-231222222221111111111111111---1112-3-113333333-311122-331---11-111---1---1---222--1-1-13332-----112-1-1----------------2-11111111232-21---13---23--22211-----213---------11-1-21-----------------------------122222----14233331222222232222226131111----1----------111-----35---------1---1-----2--12--1-111111111----4-1--21111111121111111111111111432221-223-2222212322221221221--11211------2221-211112122211-11111121211111111122221133-22122222221222225111---1--422222122222--1311111444411343---------------1111111-1-1146447563336343333-33213213-2224222222332212111111111111----------111111111---------12-12----1123-------11------1312 11114421853211111211332212322122212132222222211124336B32121222111111111111111111111111111121111111111212221244Y77575BFAC9A8BC8ACB*uB1B9J8EDAE89C67AC879C88D786736246312222345724761L2224853551332222221 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * d.126 Pentein, beta/alpha-propeller
[ 363] ------------------------22222222111---1111111111-1111-------------11 2112121133112122222-23112222222122222222222224221311111111112232322111222221111222211111111111112--253523323411111111111111231129311131211211111233423411111111111331322111111111111111111111111354555335324754422222346411142223333334212222222222221232332323222222222322222222222222222222222222223222222222222222222222222222213424333454323223442222211322121133331233111111131313855311111125553246743B22222221221-211212312381211124223313235181111111-111111111111121211111---------114411521111121212966712111133323342222333333233333323332311121111112231222222432324424412233322232121252222133222131233325221211111111111111111112111211222222322312222222222242222322--11211------23221333333332333-3333333333333233334343222223333333333233333233333332-222222222222--16323332D54225231111111111-111111111111113222222222222222222322122322222322222242223223343322211111-1211111111111111111111-1-111111111111211111112111121111713 1----------------11----11--111---1-1-----------B--1-1---------1-1-111-1-211-1111-111-1111--1---1111--11-12----821311-1----1-11-21232---2----11-1--1---1---1--1c1211111-------1122112-1-1-1114111--12--- ---1---------------1----------------1--7----------------------------------------------------------------------------------------------------------------------------------161-- * d.226 GIY-YIG endonuclease
[ 364] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111-111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111-1111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111-111111111111111111111111111111111 331122828331444222122222222222222222122222222222212222-2221211212222222-122121222222114332422332222244243618A2ED999697867687BE6J8HwA-9BR7978E78C889886965D6C69A5BE7A7BAL5FHAD854444n33343597A2544665535 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.16 S15/NS1 RNA-binding domain
[ 365] -------------------------------------------------------------------- 1122222222221222222-22222222222232222222222222222222222222112212332222211111111111312211111211111112222233222111111111-1111122222222222222221113134443333333333333343533332333333323332221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111-111111111111111111111111221111111111112221111-211111111111111111111111112222222222222333332333332222222222212222222233223333333333332222212222322222222222232222222111111111111111111111111111111222222222222222222222222222222222222222222222222222222222222222222222222222223222222222222211111112122222322211222222222222222222222222222223222222222222222222222223112222211111122221222222222122-22222222222222222222222222222222222222222222222222221222222222222112211111222222322111111111111111222222222222222222222222223321111111112222222222222222322222223222221214433331111111121111111-111111111111111111111111111112212 32--112-722-22212211111111122221211112121221112222222211222222112111-21123211-111222221212322122-111122335-2B-43535333312132542616F3-6483323323412312262254533321-22231222542125442H21233B8791A36A22227 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.45 ClpS-like
[ 366] -------------------------------------------------------------------- 2222322222222211111-12111111111122221233322332322111232122222231333322422221113333322222222222222--22222222222222222222222222222222222223333---3322222222222222222212222332222222222223111132254688B8BABA5BAABBA456666ABB5443432333333653333323223333232233232223322212222233222222222222222222222222222222111111111111122222222212448533333334344355355533432433234443432223555212222-322211111111111111111111111111111-111111111121222211111122112222222222222222222224222122222--------222222222222222212122222222222333333344443333444423333222322222222222222222222222221111111222222222222222222222222222222222232222222222222222222222222222442222222222222222222222222222221-2122211-11142224332222222222-22322222222222222224442322244444444444343444222222222322222222222222222222222222222222222222222222222222222222333333332333323331111111112232322222323322322222222222221222222222222222222--------------------------22122222222322 ------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1-------1-11--------1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.175 Penicillin binding protein dimerisation domain
[ 367] 53214A78DBADED5D724542264112831------------2--16------5238C-21135-33 4441111111111131133-321111322331112223331241162313323111121132211111111122211121131--1--2211--11----111133343---------------32355612A1222234333211433456----1-----36-53321------------1223422-B456666665744656857555644444626321222222362111111111111112111141111112211331133121111111-----12133------------------------111---111177477454455334373432222624243316998D4B9535933451---218343--1-1222131122545711111111111-22--133-34416336255653162412143323112116666666623331132------------3167234331331----12346-111135454544111155221-11113634241-4312432212422363181112112332332B32411131311311411111463342A13222111141----------------------1-98122222221111111112211111122111--26136------11221223331322143-3235542434321223222333514431211212112123211232431121-411111111211--51111111111331-1222111-33322111----------2211112112231132213---------11--1-----11---22544433333122-1--442232--------51-----1-111111111111-111111------1---1111 -----------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------1---------- ---------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.129 Double-split beta-barrel
[ 368] 333333323333333322222222211111111112211111111111122224222242211123-- 1121111122111111111-11111111111111111211111111111111111111111111111111111111221121231322445412341--131112221211111111111111111111111111111111111132321111111111111111222211111111111111112222112234346343435445432222253413422221222223332222221232222223222311111211111211112312231111141122111111111111111111111121111111111111123333333334334326333433233232242133341211121122112111111111111111111112111111111111111-11213213112111111111111111111111111111111111111111111111111211111111111111111111111111111111116111112211111111111111162121211111132512121112111112111211111121411112111221122221111111111111122111111211311211232221111221532321422124223232222222222222221-111121--11122233242222222222-3222222222222222222224322343222332233332322423222222-222232222522--2111111111111122222232332222332211211111121122222331223322431111111111254222222322221121522111623311211111111111111111111111-111-11111111111111121121212221211 1132112-733211111111111111122111232211112111111111111211111111111111111111111-211111111111211111111111121211415232321233232584431LN2-322324323222-434323-42322234C24234212422322233N3433343351373221112 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * e.10 Prokaryotic type I DNA topoisomerase
[ 369] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------- -------------------------------------------------------------------------------------------------------------4*bakaUURJGLQbR*tOnS**t-rd*ORJKhOTaPJQUNHZIGRFTPimOUWEJFB3JA9E6OJ-------------1--1-------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.7 Snake toxin-like
[ 370] -------------------------------------------------------------------- ---------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------1--------------------------1--------------1------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1------------------------------------------ 4455GC8-832-54521122111111111222311142221122121212223112314221123323-22222232-322244333333331534111232277D27JGRRVXdPRJHFIGFImYEaJz*J6YHmEFICJEIJDBHGLDQHBTJUHHL7JIIFC9AN97M9AE53779E523569LJW4S957699AE ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.207 Formin homology 2 domain (FH2 domain)
[ 371] -------------------------------------------------------------------- 131--------------------------------------------------------------1-------------------------------------21-1----------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------1------------------------------- 2211124-622-4446658544484856645455555545455565334576574464555546634434444454424433335325646363442222232B6B1771bLSFOPLGDEHGLITSGSV**T-YLbGIHDPEFMDEIHCDKB9YEGGIF8CNAC795B55D7AM825649232658CDI9LD33BDJG6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.48 N-cbl like
[ 372] 11----2111111112-1322111111112111-2---------------111--1-----221--11 1132321233321232333-32113433333322222373242225211221322225--222232344411111111-1114113331111-1-----1111111111--------------12222222222211111---42211111111111111111111111111111111111122111---21322222222222222232332322211212111111112211111111111111111111-----------------------1-1-------111------------------------111111111----------------1-111---1-11-132--111------1------11-1433311111214331122211111111111113-11211312343134412323341111131212111112122222222211111221111111111-111111111111111111111211243454554453434433774444245396B761144211122421155224112122222222211211121322-1--21----222331211111123-22111111111-1211111112111211221221222232222222222222223222---3222------21111112222222222-2212222222222221222222222312222222222222222111111111-111111111111--1222222222212422-----1-----11112221222222232222222222222222211111111111113222222222222222222221111112-222222-------------------------------------1---1-1111111 22--551-521-55534324444565533333333333333333333433444443333333311221-1321113333321111112248446442222342232-32344433331222132542235W4-3154222422332222322322212234722222634C33335253h2226484873862132224 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.103 Citrate synthase
[ 373] 2233222222222222-22222231111121133433343443222224344432222223222--22 2221611122111121211-1111111111111111211124431111121121111111451132333421---1--111222222211111111---111112111211111111111111-111111111111111111121212222222222222222222222312221112122122222---22322222222222222243332322223222111111113311121222221112211111112111111112211222121121-1111111111121111111111111111111111111111-111123211111111121222222111112112123322333332432112111222222211111123111122422222222222223-112112123121122211222134121112142222111111111111111222322211111--111111111111111111111231122222222322222223355222222329334211222331221212212222222222222222222522112212222322221232232222222211122222222222222222222222222222222222212222222222222222222221-12222------33222222333222332-322333333333322222333322322333322322223333322233332222222222222221222111112222222212221212111122221111111111222222223222222222211111111112222222222222211111111111111112122222211111111-------------------1----1---11111111112111 1111111-311-11112223232454422221222222222222224234424422222222224222143232344244433342111-2121212431111111-12122111111--111112211161-111-11111114111-11111111121111-1111121111111116111-121352211111121 ----------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------- * c.34 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
[ 374] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------6999A9A3--DGDDC9FCCBF66666666666677A9---AAA6----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------FIHAlSPRPRVYT*eSqW**u-uixUQTUWTaiaMaYVPaRMUNTJ6H---------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.9 IL8-like
[ 375] -----1-----------------1------------------------1--1-------1-------- -12-2------------------------------------3-1---1------------1---1-311---------------1---11---144----11-1636--------------------111--221311131116-727-3341-11------1--39789---------------------------------1--------------1------------------------------------------------------------------------1-------------------------------1---1111111-1--------------------1----------------11---------15IIC25153778------------11911B11-8--1--141-572---4-----23-22-1--------------4-1---------------------------------1--1--------------1111-------21------1--------21-----C------------------3-2172----16------231---1211224-3--------1------------------------1------1------1------------1-----------------------------------------------------------------------------------------------------------2-----------------111-11----------1111111111211------------11----------11111121111111--2-221111-------------------------------------------------1 1---11--1----12111-2222333211111121211----11111123222312212221-1111111121121111111111111113114291--1--1422-541*FRGFUSDDJFFFAHLEaB**Y-eLQEGCEMCEFECEGEGICCeFHEBDKOJEeIM58HA827E7-1--1--1-11--21--31----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.17 Caspase-like
[ 376] 22----6343334447-2313---52261254-----------------------------1----11 1372112111111132211-151121111112333425342342112121111111111122323222223------------33323---------111433252332--------------22-11-1--1--22222---25332211111222122232312534211111111211212122---23222222222222222223332222227744221111114321112111111111111112-------1------------------------------------------------------------------------------------------2----11---------------3-323351111114765643333443344344344413564383467414443857665A93322244555553372222222223322541222222222211222222221222-212211243-155385333343455544477988574566889227674345533546263554434222222223557433-1---11-1-111-525-2112-566634-13221111111111111111131-332222143233342333333434444423543411-53-511111111111111111111111-1111111111111111111111111111111111111111111111----111111111111111112311111232233411---111---------11111111123377774656444446222-1111111111114111114332233222222221111222-442211----------------------------------------------57-1 -2------1-----1--2---------112-12111-------122-2------1114----6-311---1-1---611---------1----1--111-1----3------11111-----1-1--1-1C--11-----1--21--------1-1--1---12-112--*-15-1-1-------1--5--1--1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.24 Cytochrome c oxidase subunit I-like
[ 377] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122CC4-1--14446666555555555554445455655655555665577777667666644444444674347758844444567658565574444555C98-A-4DORIVKIHGECDCFdTFUK**Q5UJZFEGDKEDE8ACEGCFEEYLDDDA5BG776C884485A764424Z4444DB68B6F5--2122- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.338 Oxysterol-binding protein-like
[ 378] 11----3111111112-1------1-11--31---112-----11-11--1--122332231221--- 5451521333311132211-12--33111113333346A7322154213332334134--333242546311111111---1421121-----1-----17154A5246---------------1112211122212222---431-13---11---1-1111-------11111121-121333322221-322222222122222221554322233125443323333222222222222222213323211-22-21111111221--1-13221111-----------------1111111111111--1--11111-111--------------------1---2----21-2--3112111-2--4217334-----238473265335311111111113-77377373363-6443768786553531117212121321111111141212142-----------------------------12-42133323DACAAD544448899444414A67659623554434555453924531231431111111222236512-----314--111-11-2-2-344241-4---1----------------111--2233-321444512333343345443334436--212-3------2333-332222222222-2222222222222222222232442222222222222222222222222221-211111111111---2-----111214354---1-2---------555553434352444435A5555545433---------21222324324433344343443331111111-33--11--------2-111111------22------2-----12111121111422 ----211-222-1112222-------------------------------121211-1-------------------------------1422121----1------111------------------------------------------------2-------------------1----2-1---2--1-2---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.227 OsmC-like
[ 379] 11323261222222214123333421121511434446664464234511567654353852123-11 33513-2-------13122-21--44212221333313323343-1--1-----------22222223221--------332255553111111--1---21-122211--------------1332333123435556555532233333211221111112212332211111111111111111111-1-111111111111111------111111----------1-------------------------------------------------------------------------------------------1--1211111111-13-------1-1--2--3466211-1-32--211--36-111111111736462114963611111111111-11111111111111112222212255111113555611122222222643127251111111111111111111111111111111112-11111111111111111114222212144117611111341111427111153111111111111113357134-62336545561847677818556514184333222222222222222233746553312------111111-11111112111111--241311111132334215554544455-5455544555545555555222311136666666666646466255564451-31111111111111111111122224-11-111121---------11111111114-1111111111111-1112111111112--------------12111111111111116-222222------------------------------------121111-11-4621 ------1-----11111111111111111111111111111111111111111111111111111----1--111------11111---12111261111111112-11-222112-1111111241222B1-1121111111111112-111111-121211116222121232111--------2131-3------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.18 HydB/Nqo4-like
[ 380] 22222222222222222222222222222222222222222222222222222222222222222222 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 44223332E552333333343333233333333333233323333333333333333333332233331334233243223333335553533333433332387B237463632353375364BJ4D24M6-5465233933552345132642234448333432343444334444a54444G89C3854434334 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.12 Ribosomal proteins L15p and L18e
[ 381] 11323341222222214113333321111411434456664463244511577554353852123-11 33512-1-------13122-21--44222222433213323343-1--1-----------22222223221--------332245442111111--1---21--22211--------------1322333123434446555532333433211221111112312332211111111111111111111-1-111111111111111------111111----------11------------------------------------------------------------------------------------------1--1211111111-13-------1-1--2--3466211-1-32--211--36-111111111535351114753511111111111-11111111111111113222212246111113444411122222222633126241111111111111111111111111111111112-11111111111122221113323322134116411111331111326111143111211111111113256134-62336545561847677818556514184333233333323222222233746663311------111111-11111112111111--231311111132334215554544455-5555544555545555455222311135554555555545444254444551-31111111111111111111122224-11-111121---------11111111113-1111111111111-1112111111112--------------11111111111111115-222222------------------------------------121111-11-4621 ----111-211-1112121112222312212122221222122211-111224211223111111----1--111------11111---12111111111111112-1-32211111-------22-2-4J1-321----3--2------1--1-111111-1111232121121111-----1124-41131134241 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.19 HydA/Nqo6-like
[ 382] 11--------------1----------------------------111----------------1-11 2222221222232332222-22222322222222222433222322112222222222112322333333111111112111221111111111112--121213213311111112222222122222222132111111112211121112222222222112211122422122522222221111111222222323223222321221222212112222222221122222222222222222222222222222222222222111111111111111122111111111111111111111111211111111111222222223322212222232222111111122222312211111112212211211111123222222222211111111111-33633435221122232232223311111112222212211111111111122111112222211222222222222222222211111123422333333222223233122222323223323222221111212112131111411111111122113321112111111111332221222222234111211111112411111111121122112213131111221111111111111111311-1221111111111222222222222222-222222222222222222222222352212222222222222122222222222222222222221141222222332111121111111111111112222221221123333244322222123312212122211111111111111121222222211111111122112222222222111----1-111-111---11111-11111111111112312 21------2----12--------1-1------------------------21-111--------------1-1--1-1-11-----111--1--1-1111----1-21119344431444524233263EW6-66A222162454232323227334223332413-3222115412217111112222-221121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.46 FMT C-terminal domain-like
[ 383] -------------------------------------------------------------------- -----22-224-2------------------------------------111-22--------3-----1-2---222----------------------------------------------------------------------------------------------------------------16C6969A68AD96666AODLLMG8866862847NPRTOQ942AAA8AA8AAAAAAA74445H6--FL--8-8IJ--DO-274433425879979967A88868A6A48666666666666669822-999B-5-BcCCCEAAEBA9-o--2222-2-2-8-3-----2--2---GFB--11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------21-----------------------------------------7584-734118488863-1444688642182444444787AB332747657787874846664314444--811111111111---------------------411-1111-111---------------------------------------233----------------------------2-----------------------------------3-------------------- -------------2------------------------------------------------------------------------------------------------------------------------------------------------------------2---------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.142 PTS-regulatory domain, PRD
[ 384] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------*gcWORYPKQHPUOdWORM**Y1rT*IRNKZOQZU6SHMISJGnNiPUO8BF537GAHLGBCHn6------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.28 Thyroglobulin type-1 domain
[ 385] -----------------2-------------------------1--22-------------------- 131-211111111111111-11112-11111111111111122221212111121111--11141113321-------2-1-21-11133451311---11122111222222222222222212221212222433344---222322222-111------121-1211------------11111222111111111111111111211111111111-111111111111111111111111111111111-2112-11111--11111---1111111111111111111111111111111111111113111111121113111111121222111333212221432233222211232212311112-----------1--1---------------------1--1--1111111111111111----------------------------212--------------------------------1----------------------------------------21-1111-21---31---1--------11111113331121121111133322232111112333--------------------11111--11111111312-------------------1--1-1211111111111111111111111-1111111111111111111222221111111111111111111211111111-11111111111111112222211111111-111111111111111--------------------------------------1111111111111111111111111111111211111112222222222211111---1111111111111111133333242221231 4544222-6111222222222224244222222222222222222232222222222222222444442464444442544444442222422222333322344422415GIFJB57684767685C7Q*8-ICA7457C88A13882265758B66426L83422623546223333P22243EDIH2B63211114 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.89 Phosphofructokinase
[ 386] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111212111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 45222231B44233333343333333233333333334433333332333333333323333444444244444455555434443555362333433333435651482533353563433627B2847b5-45A3332734671353133252333345433432635434334444p3254487BB3A43353331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.24 Ribosomal protein L1
[ 387] 11111111111111111111111111111111111111111112111111111111111111111111 1121111111111111111-1111111111111111111111111111111111111111111211111111111111----111111222222221222222221222111111111111111111111111111111111111-111111----------11111111------------22222111-11---------------111111---111111111111123111111111111111111111---------------------------------------------------------------------133-22222222222-11133322121121121222222111111111--212111111111112222222222211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122222222222222222222222222222222222222222222222222222222222222222322222222222222222222222222222222222221111111111111111111111112112222222222222222222222222222222-2111122222222222222222222122-2222222222222222222222222222222222222222222222222222122222222222222221111122221222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211111111111111111111111---------------------11111111111222 3322331-72222222221222232333322223332222222222222222222222222222222222222222212222222222222222222222212223227243222132222222232326G2-2362212322222221222252232236E22234212422322333f33333477A2554343333 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.53 Ribosomal protein L25-like
[ 388] ------1111111111--------11111111-----------1--11-2122--------1----11 111-211111111123322-23--242222223333323311-123121111222111--1131112242111111111132------2211-111---1412233232--------------1---111111-2-----111-14--------11111111-1------111-11111--1--------2-32323313113121212222242312-2222232222222222222222222222122226112222-21111--2221223121121111112111111111111211112111111112113322112121111111111-1-2111-111211221-111321-12221111111111-13111-----212231111121111111111111-22123212231-1222221222231111111111111121111111121121111-----------------------------11111-111111111111111111211111111111111--11112111122211111-11211111111113111111221222112222-11111212311212122-1-11---------------1-11112311121111111222211111121111111----121------23111322222222322-22242222232222222225321111222121312314333232-122221--211111111211---11-1114332-2122111111-----11111224211-111-111111111111111111-1111-1-1211211121211112112111111------2-11--11--------1-3----1-1111111111111111111-1--------2212 ------3-84B11142433333333343312223333333233222333332332333333322222212212222211222222133335343333333-33331-5B2844346C44343449A3A3Ab5-577334344444343344339363443-335443433834831443B332353353346233222- ------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------ * d.240 Lesion bypass DNA polymerase (Y-family), little finger domain
[ 389] -------------------------------------------------------------------- 11-----------------------------------------------------------------------------------------------------------------------------------1-------------------------------1----------------21111--112-----------------1-------231C---------IP---------------------------------------------------------------------------1--------------2F7111111111-11B-11----3-Y11L1-EL--RLLD2X-I1283M--1----------------------------------------------------------------------------------------1--1111111111111111111111111----------11111111111111111111111111111111111111111111111111111---111111111----11----------------------1-----11---------------------------11111---1-1111111111111111111111------1111111111111-2111211122-122211121211111211222211111111111111111111111111111--111111111111---1--------------111111-1111111111111-----1-11111111111111111----------11111111111111--------------------------------11---------------------------------------- -111545-211-22422343333333333233333333133333333333333323333333233222-3223322222223333323245423343443324AAB1342BC9BDFA88888A7VN6I6h*G3KCJ9777969AA69757E77O9A88A4599A776G4357C86111171112173153321232332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.82 N domain of copper amine oxidase-like
[ 390] ---------------------------------------------4----11---------------- ----11---------------1--3--------1-1-412--1-2----31-2-1------13-111548---------------1--1142-1-----144514-12---------------2--------11-1-------3-121111-----------11-22432------------1-1------11222221-1231-13---1112-21111-122----1--211----------1--1-1-------2--2--1---11-1-------1--2------------------1----------------------3----------3222--------------1-----------------1-1-1-11-------1-1121-----1----------1-121154112------2--1--42-------1221-----11111111-1-3-1-1-----------------------------------141221--1--4----3212------171--12113141-3--6A22---2-----1111----1-3-2--3-1-2---1-1---11-311---311--31-------141111--1221111-------22111-2-4111224121311132112113---1----1-11121121122222225222-121247322232222222141111522232222222211212222212221--343344333543-------------12211-------1--1----11211111112-333421542442314251111111111112211111342632332322111------3-11----111111111-4------11--1-------------------------1-4 --11362-42211231121111121221111111111111111111221131411111111111111111111111111111111111111111111111211X23-532dHGEGS58667769997B8Kw91B9E4778A789958674EA5H9B89J4753G4G7GBF54467-19-C111-221-31-12222114 ---1-112------1----1-4-------------112-3-1---1-----------11--11-331-31--1--------3-------11---121--2--611---------------1-----1-----------1----1---------1----4-8---3---5-5542- * d.4 His-Me finger endonucleases
[ 391] 1111-11111111111111111132222222411122222222222222222212211211111--11 2121221111112122222-42112222222222222222122222222222222223--2221322232111111111---221311111111---11-111222121--------11-----21121122122212112222122322222222222222222223321222111212212222222-222333333331333333224422333222322222222223122212222222222222221-1-22-----1111221---1-222---111122222222222222-------------2114311111221211111111111212211112121-22122224322112222221-22122113-----113222112221211111111112-22122122322-2332222222222111233223223221111111111111221-----------------------------11212111111233332232332222333323322344212444322422233222222111211111111111222112111111111111111111111222222222111-11111-11-1111112111211223211222122222323222222233233--1122211-11133332333333333333-3333333333333333333333332123332333333323233333333332-32133442333311-3-----122222322111111-11111-11222222211121222222222222232221--11111-23333222223333311111111111111221-111111--------1-1----1-111211111111111111111211212221311 ------1-----1111111111111111111111111221211111111111111111111-111111-1111111111111111-11112111111111111111-12-112111-1--111-121217E1-113-1-1--1---111-1--11--11----512-------1-21-191111131241223121211 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.27 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
[ 392] 11-1--1111111111-11111111--11211111111111111111111211111-----1--1-11 2131211211111121111-121114111111211133332113242-211123111111121-23423211111111-11-111111111112---11-211211212---------------11111111111111111111111111111111111111111121111111111111111111111-11111111111111111121111111112211--1111111211111111111111111112---------------------1-111-------11111111111111-------------111222111-14-23111111111121112---2-1--1211122111111111111--12135444-22-2526771134543333333333225-33433537851-5554536666775522233423444342122222251122111-----------------------------2226222552746656452222557A222223447664512552325336463982211222212232222111311-2211111111111-1111111111111-3111111111112111111111111111222243323-2332322322233332222322-1-121111111122212314222422222-2232222222233223222222211123232323333323222322222221-22222222222211-------111122246111111-111111114444423111422222223322224333311-1-11-1121312222222123222222222222221111111111--------------------------------------1--1-111131- ------1-------134224464575622222222222222222222234334444333222111111111111111-1121111111123242222222112222--4----------------------------------------------------------------1-1111I1111111352121133342 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.334 IlvD/EDD N-terminal domain-like
[ 393] 113-1-2322223323--21111-2---1--------------------------------1------ 13914---------1--11-12--5711111333331369221311---11-2121----1-B-3495551-------1---3---1-------------1-245-5----------------------------22211----5-1-111---------------1-2--------------22-------1-----1---------12---1----21-----------1--------------------1----------------------------------------------------------------------53-24444344434-4------31-21-112-311332-213-------4--4232-----24FGH41337495111111111-1-A9E88CAD562-62241284318C7523-66144445564444444463331521------------------------------2351-45445ABBBBA22221BBCC22221285GCAD4-2665433118251A2131-1111-----------2211-3-4111121111--1113111311-133-4-------------------------222--4112-4-112222232111111--1-1----1---------1--2--3332322132-3333212323322332331------------------------51--1112-----------------------------321---------------1111111-214166663284464553433---------1---3----------1122222----------2--------------11---------------------------2222-----13-- ----111-----11-21222121121222232211111111112222211112211111111-----------1-----------------11-------1-1----263F23223822222426E252352-32422224226222222B1292623326N2874B6AD8B356-13-8---2344672761121112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.56 CO dehydrogenase ISP C-domain like
[ 394] ------------------1-111-------1-113--------12321-2531--------------- ----4--2223----------2--12------21215332-1-222121-1-332-11--22115-313211---1--2-31------435--2--1--21232312-1--------------1121-22--112---111115--11-11--------------1-1-1-------------2-------127777799837988884B77567771-16212444442791222222222222222223211------1--22111---1---231111----122-11---1--1--------------11111-111--564ABDB9CE95B58J42-11-F523-2---1CA1-111-1------121-4122------2134411132222------------11211112-2--311-22233311111-112-2222-11--------1---11-2-----------2--11--1----------11-1--11112111111-----1131------3-2----11112--1111--211----1124--------------211-3-13213222-22----211--1-11-1311---1-----1-------11-----34---2--1111111141-111121-1123-----1-------22222213444444454-4446443444444443442454121134434434434444444423222232-333323313222-----2----11-1-113-----------------1---112-11111134121111-----1111-11111223------5244321-1211----------1331122--------2-1------------------------------------2-- --------------1---------------------------------------------------------------------------------------------B2*974864422323244232DD3-23323124445213332331634844336-197-----127-17748333787598-744611221 ------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------ * d.60 Probable bacterial effector-binding domain
[ 395] 1111-11111111111-121121----------1-11-1111-1-121-----1111111----1--- 1221311111111111111-1111111111111111111111111113111111111111121221221111111111232221122233332333222222222222211111111111111111111111111222222222311111111111111111111111111111111111113221122123322222222222222243333322234332222222224222222222222222222222224222231212233333231113333332222422222222222222222222222222433111333222333333333324226332232222223222233222222222232122221111111111111111111111111111111111-2111111112112111222223111111111111111111111111111111111111111111111121121111111111111111111111122222222222222222222222222222222322111211121222222232111112122222112122111111221122222222222223222-1111111111---------1---1223322222222222222222222222222222-2222222222223222322221222222-2222222222222222222323222223323333333233333222222122122222222222222222222222222232222232222222222222222221112233332222222222222222222222222222222222222222222222222222213121111--------11222221-1211211---11111111121122222221112 12--1-1-1---111-22211112221111111111-11---11111112112111---1111111111---11------1-----11--2-2-11----1--1-1-13-2221113-11--1-11---191-111--1-1--111111-1111-111-13-1211-1---1112-1--9--11--12-1-----1111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.153 PheT/TilS domain
[ 396] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------L765334556799AHAA555489A3C86AD978BB67------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------1----------------------------------------------------------------------------------------------------*---------------------1--------------------------------------------4inb*NNLUi*Q*h-cLhh----* -----1-----------------21------------------------------------------------------------------------------------------------------------------------------------------------------ * f.43 Chlorophyll a-b binding protein
[ 397] ------------------------------------------------1-1----------------- -2------------------------------------------------------------------1-------------------------------2---A---------------------------------1---1--------1-----------------------------------2-------------------------------------------1----------------------------------------------------------------------------------------------1----------1--------------------------------------221---------------------------------------------------------22-------1----------------1----------------------------------1-----------------------------------------------1--------------------1------1------------------------22-----------------------------1----1----4------------------------------------2-------------------------------------1----------------------------433333333334---------------2----------------------------4----------------------------2141222-----------------------------------------------------------------------------1-- ----22---1----------------1-----------------------11----21-1-1------------------------------------------------8**nq*aMJLLORJoSJYLp*S-aLiLOMKkNOWHHSJHETKJoLaFJ*11--1-1-------1----1-11-----1---H-----1- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * b.11 gamma-Crystallin-like
[ 398] -------------------------------------------------------------------- --------------------------------------------------------------1-1--------------------111---------------------------------------------------------111-221--11------1---11----------------------------------------11--------------111111----------------------1-111111-1-11--11--1111-----------11---------------------------111--------------------------------------------------------1----------1111---11111--------------1------1--------1---11-11-------------------------111-----------------------------------------11-1-------------------111--1---1------------21-1---11-----112-11------------------------------------------11111111111--11--111-------1------1---------------1---------1----1----------------------------------11----1--------------1----------------------------------1-1-------1--------1--------------------1-----------------111111111112111--11111------------------------------------------------------------------- 11------311-111-221----111311----2321111111---1111332433211111------------------------------2--A-----------141MJWUYXSHFIIEHISOJPGi*O-TPXFLKIQIGLIIGFJDMIJQJHKIMAABOEHQBGDFj578823414---43598819L54DDAE1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.74 Carbonic anhydrase
[ 399] -------------------------1------11---------------------------------- -11-1---11--2-11-11-1---23111111----233411--122-221-222116---22-2224-2-11111111-----1----1-1--11----2---322----------11----------------11111----1-1-----12-----------3--11-------2----21--2---1122222232412323341232232212124121111111221111111111111112111221--11--1-112111111--1----1111---1--122111111111111111111111121---1111-----11111-1-1---11----1-------1-1-----1-------1--1121---11-111-11--------1-2-51----------------1---11-11233121------------2--11111111---1----1--------------------------------------11--1-1-----112-------112--12----1-----2---11----1---1------------11---1--1-12----111-11111--1-1--------1-------------------22-----1--211--------------------------------------1--------------------------------------1---------1--------1--------------------------------1----1-1--------------1----1-----1------11--11111--------------1--1-----------1---------1-222222---11-----------------------2------------------2-- 231-742-72213453699D466BCAC555557546647654676678539F8G77A96635335246454464332122654665444EI8678934425B597622D5K443528467A82B666B6Ao2-94F68773C34333AB7-848862389574F36A261983892344a2-25589DI97A24A7476 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.16 FAD-linked reductases, C-terminal domain
[ 400] 11112121122222221221122122221222121111111111111111111111112121111-22 1111311111111111111-1111111111111111111113123111111223212111221211132222222222111211111111211111---1121111111--------------1111111111111111111111222222222222222222222222222222222222211---11112222222222222222212222222222212322222232121111111111111111111111111111111111111111111111111111111222222222221111111111111111221111111111111111111111111111111111111111111111111111211111111111111111221111111111111111111-22122122111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111211111111221211-1111111-11111111111111111111-111111111111111111111111112-111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111-----1---1--11----111--11112111121111211 1111222-311133433333333333333343333333343333333333333233333333332222223322233-3322222234423232425332132434121-5443645211122276281BM3-63511225-2211222121162342322422232B23523212332K4323254573452242222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.52 NAD kinase/diacylglycerol kinase-like
[ 401] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3233555-72B91132222222222222212222222222112222222222222222222211222222221222212222221211122222311111121413-589BDJ9A8MMOLIMMLmUIVNy*T-bSjDMKKSLGSFJMLIDPH8mFPFGHFE4CF3213132NQ621454B33323A6682B52114335 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.83 Aha1/BPI domain-like
[ 402] ----1-----------1------11--1-1-----111222212213211121--11-1-1---1-12 -11-111111111-11111-12112211111-22222245121231-1-221122111--111221352211111111-11121-1112222-211---1411121312--------------111111111211122122221-1121222--112---11-211112-------------233----1-12223233332333333--22123332332-2233333334222222222222222322321111341121222112221211234433331112112222222222212222111111212212221113--1222222222121122222221-111-112-11121---11----1111-1222------224321-12212211111111111-22523423151-32223343431322111---1-11--122222222-2222322------------1-11-1111-11------11221111-1222222221112222222211223343412322332224232423321-111---------121121221-121-212221222222112112111122----11111-1111111111122-33222--1-121222222232222222212111--1--1------23222222222222222-2222222222222222222333222212222222222232222422222221122222222222211-1-----2222-221311111111111111122222221112233334343133321444-----1---1----11111-1-1111222222221111--1-11--11--------1----------------------------111111111-111 ----33--217-1135334555566663344443334444445434343333334433333333222212212428314322223422235335452333133675-222------------------------------------------------------------1-----2122-----231332---65572 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.328 CorA soluble domain-like
[ 403] 22121222222222221111111222222222222222222222222222222211111111--1122 2221322222212112222-2111222222221222222222222112111112211111222121222222111111-1222112221111-1111--111112223211111111111111122222222222222222222212211111111111111111211121111111111112222222122222222222222222222222222222222222222222211111111111111111111222122122222222222222221111111111211111111111111111111111111111111111122132222222222221222111223122122233121122222222211211111112112222222222222222222222222-222222222221222222222222222222222222222222222222221222211111111111111111111111111111222222222222122222222222222222122222222222222222222222222222222222222222222222121212222222222221222213333313322222222212111111111222232211-1221-1111111111111111111111--22222--------------------------------------------------------------------------------------------122212222222212---------------222222222212222211111111111112222222222111111111111111111111111111111212222221111111111-----1-111111111111111111122222222222221 1---11------1132222222222122212222222222222222112211212211222222122221222212212221111112121322232321222222-2-11211111211-1113-211161-11111112111111111111111111-31-1111111-----1123L2221111132322111111 -------------------1---------------11------------------------------------------------------------------------------------------------------------------------------------------ * a.182 GatB/YqeY motif
[ 404] -----------------------1-----------------------------61111111------- 2221222222222222222-22112222222222222222222222222221222222--22222222222-1111112222111111111111111--111111112111111111111111122222222222111111111122222222222222222222122222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222222222222222222232222222222222222222222222222222222222221222222222222222122221222222222222222222222222222222222-22222222222222222222222222222222222222222222222222222231111111111111111111111111111112222222222222222222222222212222222222222222222222222222223222222222222222232122222222222222222222222222222221111111111111111111111111222222222222222222222222222222221-2222211111122222222222222122-2222222222222222222222222222222222222222222222222222-222222222222112222222222222222222212222212222222222222222222222222222222222222122122222222222222222222222222222221211111111111111111111122-1121111111-2111111112122212221321 ------------------------------------------------------------------------------------------------------------4------------------------------------------------------------------1-1-----1-2222-22-11---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.79 NusB-like
[ 405] 11112211211122222211111223321343444232222322212121211122222222221111 -1138------11-1--44-4-115-434445-----1112----1------212--1--222----221-----111--111--1--1111-111------21--2-1---------------11111111121---11111111--1---11------1-11-11111---------------3311--11122233222242343-211--423-111---11111122--------------------1-2-11-11-12211111211-1111--------------------------------------------121--2222222121-111111-111--2---211212313211121-111-12111-----1221-1111------------------3--3-1--1-------1---11--1113112111111--------111--131------------------------------1--1--11112222222111122122222222211111--111-1---13131-2----1-1--------1-222--111---11111111-2--1311122321111------------1------------6512-11-2-1121-----21----1-11-11---1111------1111-111111111111-1111111111111111112---11---111111111121111211111111----------------12-----22121131-111-1-1----1--122222222321-11112221122221111111111111----1111111111112---------------2----------------1-------------------------221221211111-- 321342418322221223322322223333333222122221233322333333234222122222222121222222222222222222322222222215222224145898G797567685GF5H6V*C3J9I4557A47A626774C44E6C67522353352333735442222F2222234453543315442 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.230 Dodecin subunit-like
[ 406] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4--Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------5-----1111111122111211112-1111111111111-1-112231112111111-----------------------1111-111112-21111323121-FMNJPEXEGLGHPG*iDdG**Z1gO*DJFFj9GvVEJFHDTDDjDKEGG45CR8664C66I446D----8113G---1-1--------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.20 Blood coagulation inhibitor (disintegrin)
[ 407] -------------------------------------------------------------------- 3331------------------------------------1---1---1--1-1--------1-1------------------33333-------------------3------------------------------------3---------------------------------------------233222222222222222333333222333333322222233------------------------------------------------------------------------------------------33333333333343433333---333--23332333433332333333--33333333----337473345844733333333333-6666636733333334433444334-3333336666333--------1443-565--------------------------------333332333444733333333433336364333333--533333333--363333333363-------333-33333-3344446445433333333333-3--3-4444-4444444444444444443---36-333333333633383633363366663---333332-33363333333333333333-3633633233336333333---3333333333333333333333321223233356666666664---------3333--834-------------------------3333333333633433555---------3333633333663333333333336------333333333333333333--------------------------3-33334233-3-- --------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1-------------3-----3---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.152 Flagellar hook protein flgE
[ 408] 11111111111111111111111222222222111111111112222221333111111111111-11 1221222222222222233-33223233333333332222222223222222222222222222222233211111111111111111111111111--1111111111111111111111111111111111111111111111221111111111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122222222232222122212221211111111112211212111111112111111-----112221111122111111111111-222222211111111111111111111111111111111111111112111111111------111111111111111111111111111111111112111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111121111-1111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111------------------1------11111111111111 12-1221-3112222222222422232222222343222232222222222222222222223333331343333333333443442221212216122113112212514222131222212366262GT4-642222242242221222224222233112222-233212222223G3223235492AD2232222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.101 Undecaprenyl diphosphate synthase
[ 409] 11----1111111111-111111-12221221--1--------2--111-111--------111--12 111--11111111121111-1-1112111111-1111211-111112-111111111111---11121211-----------111-111111-1111--122113121211111111111111111111111121111111112121222221111----1111222231------------11111---122333333333333333322222333222111111111131122222222222222111111---11-----------1-----11111111111111111111111111111111111111111111111-1-12222222222211222111111--2---122-211-1-1--1---1211122111111213111121212212111112122-112114111111133111111111211211111111111111111111111112111111111111111111111111111111-11321122221111111111111111111111521112-111111211212131111211121-1111111111112---1-31-1-111-111-111--111112121111111111111111111112---11221111121111111111121111111111111111111-11121111212222222222-222222222222222222222211212222222222222222222222222112222222222221111111111111211211111111111111111111113111122222222212222122211111111111112222222222233232333332222---111----11111111--11112-----------------------1-------2211 2211221-F66-9B2333233333323333333222222222233322333333443333334342333333434332333444333334543334222221321211242131112111-13111111483-3131-1111211111--2111111121112311111331233367171115633863732342212 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.44 Fe,Mn superoxide dismutase (SOD), C-terminal domain
[ 410] -------------------------------------------------------------------- 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 2211422-832-111-1111111111111111111111111111--1111111111111111211111111111111-1111111121113212221111112649-2D2DBB89474575444FC3B4Kt9-C5743358554644543552F3655524B35731933535932232G2222358KB1882223223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.144 PABP domain-like
[ 411] 11----859888898B2774612645311122--53383333231-1-316762------11461--1 ---51--------------------1------1----13114121---2---1-------225----1111-------1111-5B5661121-122------5--1-2----------------1565685562532233----313--33111111-1---111-----1----11----11-11133-121--1-1111-111111--11111112211121------11122111211122211112--1---1------11--11--1-------------------------------------------------1-23-333333323221222-2212--11--1223333322225--4252-122----------16442131-111------------142-6-41-1--1--1---31---11--12------2-21111111122211511------------------------------1-11--11---------------11-------1111231111113-3111111-12-B-1--2------------3-4411455256433-1212121316556222531121111111-1-------31213BB4445423344345555344555444444533-1175I33333344335434444444444-4444444444444444444445334444444444444444444434444443-444444444444--34---------4545444444433332333433333322213444443333333333333---------833343333333333----3---------4561--------------2-------------------------------13333333-- ----11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.114 DsrEFH-like
[ 412] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 33112211933132322232222222222222222222222222222222222222222211212222122322233323222222333242222222222224551232323222222A52328C2J38bC-2492223C12K23222121232532223223222526233323333a3323365782432222221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.55 Ribosomal protein L22
[ 413] 111-11111111211111------2-----1--------1---1----1---112222311-111-11 1231111111111122111-11111111111111111211111311-11111212121--123-1112111----------11-----112311111--111122-1411111111111111122223222222211111---3-3113112--11---------------------1----112111121222222222222222222222222232222322111111222222222222222222222212212212212222222121111111111111122211111111111222222222322211111111123112222222222222133132231221-2211116-1-21-232331312-11112-1111122223232322212221121212-22122222242142221222223322-112223333322--------2221122B------------------------------3383122212222232222222222222222222222222222222222222211152111111111111221333-121111--32----3232325132222342411111111111---------1-112111122111121311111111111111111111--1231------11111111111111111-11111111111111111112221211111111111111111112121111111111111111111--1122222--11-12121111111111111111111111---2-111111111-111112211111311111111111111111111322223221111--22222222---------24----1-1-1-111---11111-11122122111113221 11--341-6211121111111111111111111111111112111111121111-1111111111111-11111111111111111---12111211111111332-23125222233223323224423J3-244422322224422312312331231185422341353941115-----3153541211137471 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.91 PEP carboxykinase-like
[ 414] --------------------------------------------------------------22---- 3361322222122222222-22--3322222321212232131232112321132111----2-1224532-----------------------------9164D5A24------------------1-1---2-22222---12---------------2--1-1-----------------1233---1--------------------------11121111111111113333333323333322211--------------------1-----------------------------------------------------------------------------2--------------------43-1345223333444222223522244444444445-5434444A33115333645133335335431522226221111111122242-12------------------------------23132-11113334335777733668888574364544-2445242-222213-43343333-211222211-544511-2-1121---1-2221122-2445542--5-11-11111113111111111--111343335123413233342232333323323--112-1------22131312222222222-2222222222222222222223443224343444444444434422222221-221222122212---4-----332211213----1121111---111111122332466665765334542434---------11223111113121166555655664444----332233-----------------------------------------------4-7 3222----2-14---21------122------------------------2222--------------------------------------1--------------1-4D1211231111111232215E2-414111111111111-11114173231111421-------42------------11-----1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.61 Streptavidin-like
[ 415] ------------------------2---2-24------1----------------------------- -----11-11111-31411-12--1311111142223442-1-12----22-1--2----25--3-2222--------2--1111------1------------2-11---------------------------32122---4-CC43444332232432222235433324333333433331------21333333332323332233311332---1322------22233333333333333333311--------------------------------------------------------------------------1111111-1---11-11111-----1--111--1----------12-11111-22-2343552225324344444444444-5464444523--55556638775554---32522442222222222211133212-------------------------------11--354224555543333355733333335333543112231211172113321513121-1111111---12------11111111--------1------11-2---------1-1-1111111-------111--11-1----------------------------------31211111112122211-11-111111112111111111512--1111111111111111121111111----------------------------2212---------------11111-2---3133333546233431444111111111-------------2-11111111111111--2111---------------------------------------------------1-- 1-11224-----11221211222222111------211-1111111--1112122221-1--222122111121111-111-11111-11111--1222-121121-2X61-211121---11111-4-Vd7-9311-1111111111--1212-2111---1-21----3---12BB5*655954324222476755B ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.237 Hypothetical protein YjiA, C-terminal domain
[ 416] --111111111111111---1--111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111211111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111131111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 22111111834122222222222222222122222212122222222222222222222222222222222322233233222222333232222222222224571231324222422C113-7B-J25V7-54C4425722732268252232112222121221422222323333c33323B43A2632242223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.47 Ribosomal L11/L12e N-terminal domain
[ 417] ----------------------------------1----------2----111--------------- 1211322222222211111-111111111111111132211331223132223332231144212233422233333311331122221111-11111111111211111111111111111121111111111111111111212222222221111112111122222121111121111111111111222222222222222221122222222223122111111312222222222222222222212221122222222211222111111222222221122222222222222222222222222222222221132344444333422244233211111124111122111111111111111111111111121211111111112222222122212222222211212222222222222211123333332332222222222222122223222221111333313333133111111111112222223223222222222222222222222221222222222222222332222212111111122222211111111111111122222222211113311111111111111111111112112222211111212122333332233332322322111112111111111111111111111121-111111111111111111111211212111111111111111111111111111111111111111111222212333211111111111111111112222212111112222222212222122222212222211112222221212211222222221111112111111111-11111111----1-111-111---11111111211111111111121 11--11--412-111--------------------------------------------------------------------------------------------151211111-----11111-1-151--11------1211------11--112------212118--231322C222114313-371321113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.167 Peptide deformylase
[ 418] 11--1-2344444444-222222-2---1222----------------------222---1321--11 32--31112221-231-----3--24-----142223444-424312113312122-3--1122215423211111-1----3-1-----2-----1---212-3131211111111111111----------1--1111---1262532242222211111222345652311222221121-211---21122222222223222221222122211--2111111111121111111111111-211111-111111-------111-111-111111-------22222222221---------------------------1-------1-1----1221-1---------------1------------3112-----43344-233222311111111112-33233233----11112213321123---2-342214222122222223222122--------11-------11---11-3-33-------3311122221A111122161112-1-324221--22-241--11--22231-1231111111111111111---2-----------------------66-------111111--1111111-------111213111-2-----3------------2---22-1-------112--1------------------------------444-1-2-----------------1------------------------11111122331-232111----1111---17675645---2166766666276883667----------111111111121-111222224332111--11332222----------------------------------------------1--1 2-------1-----42445222222212222221111111111222223234343332233333413333343534545533333443335242324331212423--B115522452132342632327I2-223-22221221-222121-32421211-222112212--2-2354B33374846646564-1115 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * a.132 Heme oxygenase-like
[ 419] -------------------------------------------------------------------- --1-22221121-121122-22--1322222122324112132111--1-------22----21313B891------111-22-----11A5-6111---11113---1----------------1-------1-77766---922--3-----22212122--11111--1-----1----1--------127674766655558761-3315459-1-31--41112121321111122133221111242121-11--1---44--1112-1-----------1111111222122----------------------1-21--31321-21121-321321-13--3-121531-21-21-1----112--211121111111221131111211111111111-21111111111-111111111111211111121311211--------1---1121----------1122--22121-22-1-1111121-22222222222244442212444424322111111112113115221411111211321111111121122-32-------1---------1-------2--1--------------------1---111221211112111111121111111111121--12113------22224232222222222-2222222222222222222222221122322222222222222222222223-233333333333--211111121122132-11111131211112111111111222133432233232222322111111111121111111111111222222222211111-12223333----------4---------------------------1--------131 -----------------------1-11111111----------111----------------------------------------------------------------P5522426761266793869L6-76A675525463-245674543--23----87-CPGBG---1---1---------------1---- ----1-11------11----------------------------------------------1-11--1-----------11---------1-1-1---1----1------1--------1---1-11-----1--------------1-----------------1-------- * d.118 N-acetylmuramoyl-L-alanine amidase-like
[ 420] ----------------------------1-1------------------------------------- ---2322111112121111-11--14111111133313221---21312221434113--11224562331-------44653----------1----------1----------------------------1-2224477731--1--------------------1-------------3443222--326666666646666665333326664323466555556233333333343333334343455635643444882255465225645555644643333333533333464474446446457644266661644555555558671355555495-443671166-1-4742-3221321--------------11----------122-222-24-11111-1114--311-233552331----1------2----------1111---2-----------------------------------------111111211111212222111111111--11-2----1-3--1----211----------11--1-------2-12222--------------11-----------------------------11--11-------------------------------------23--21-1111121211--111211111-111111112221---2----------------111-111---111111111111---------11111--2-1112-1--------1---------1111111-----------11-------------1------1---1111111----------1--------------1-922222-2131222---3332222224632222223---- ----11--21---1123221111111211111111112111111111136223433222222314112-11111322122111111112112312132221-1111-1214112112121111111211371-113111-1-1112122111-1111111--11212--25311--11181111121152211121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.119 DAK1/DegV-like
[ 421] -----------------------1322-1-12--1--------13-21-------------------- --2--1-12221-------------------------11-----3211111-112-1---11221-1222-----221--3-1111113322-211---11141--1-1---------------111-1-1-21-11111---3-111111-22221---1-32--1---------------43222113124336464564656665444444666131333322222244144444444444444233434233223-3322111231--3112222331111122-----------11111111111112443324442-5132-------3-421--155422---1--------21--2-222-3-23-1---------1-3331-121232------------2331312-12--233222222212-1---3232122333--------1----111-------------------------------1--------111111-111111--11111111-211211222312222-1-1-2116---3------------11-11---2-111---1---1----112-184111--1-------1-11111111--13--441-12-11113333333533333335354-----12------22221222224255522-222255424225322222332333323444444443433434242333213--311112212211---------1111112-3333232-22211--2111-111---1------1--11-1-1---1--------134454444455343--------------1114--------------211------11-1---1111---1-1112222211111-111 --11--2-----4632222344211141111-14341111111111--33223222212222--1----------------11------12124211111--2113-253D312112111111-212315C1-311-11111111111111122111111226334B9BAB--13-32111125-1--12--6333354 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.114 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
[ 422] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-11111111111111111111111111111111111111-111111111111111111111111111111111-1111-111111111-1---------------111111111111111111111-------------------------------------11111---111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111-11111111111111-111-----111--111111111111111111111111111111111-111111111111-1-111-111111111111111111111111111111111-11------------1111111111111-----1111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111-11111111111111111-------------------------111111111111111111111111111111-11-1-11111111111111111111111-11-111111111111111111111111111111111111111111111111111111111111--1111-1111111111-111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111-11111---------------------1111111111---1 22222221935122222331222221222222222222221222221222221222212222233333233223324132323332344242222212221224571222455343235664425H4O4K*9-87C344CC23C53313542443443314432221438211222222I2222285683822211111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.59 Ribosomal protein L30p/L7e
[ 423] ----------------1-------1---1-1-114------------------4-------------- ---13221111-2--------1---2------11111212---1112123324451-2--1-132231121----1111--11------------------------1-1111111111111121111111111123322---2---1--------------------1-------------12---1-243333333333333333343443333333342222222226411111111111111121111211122111112211222121111112222222222222222222222222222222222222222222233133333333323222223222513322862---12--31-244431331-12331-2222112211111111111111111112-11211121121-111112222111111111112222111--------32212112------------------------------1211111111333333222222223333324333123211223112112111121111111511111111111111-232-112122222-11111111111111211------------------------1115551111111322222222222222222221-1111111-11163333336667686766-6656866666677665666556332336435444544556555455355532-444444444434112-111111111-11213333331333311122222212---2133333434222222222----------4445444444444422222222221111---511111122222222112----1-1-1111111111111111111-1121111121- -----1-----------------1-------------------------------------------------------------------------------------------------------------------------------------------1------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.94 HPr-like
[ 424] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 2111222183313231222122222222232222221222222222222222222222122222222212222222313322222234422222222222222357126232422232231232332735Z5-4582132422242212121122232322123222222222223333e3333397B72752232222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.21 Ribosomal protein L13
[ 425] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------1---------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----km2---1----1----11131----------------------1111------------------------------------------3-1----1---2--B3FIKIAIIQ8877AK9PC5XB**Y-UQn7C99KABQH1EB48H97NBE9EEAfN9CvCAOEJ8LfGT-5-38113444874-4---7ABK- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.64 Saposin-like
[ 426] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----446-----11---------------------------------------------------------------------------------------------C45HQUPRRTLEHJKJGiWIRI**WBaSxEKIHYGLOJCKJDEOGDdKSPJI9CG9FD99E78L88C9----2--------------23331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.256 RUN domain-like
[ 427] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111-111111111111111111112211111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 2221222163212122222222222222222122122222122222222222222222222222222212212223332322222223325222222222122445125245424222431322332527Q4-2371222422522321-21143212235424224222B22323333Y3333385C62542232223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.22 Ribosomal protein L4
[ 428] --------------------------------------11111------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111222222221-1211121121111111111111111111111111111222211112111111111111111111111111111111111111111111121112111111111111111122111111111111111111111211111111111111111111122311312222222111221111111111111111111111111111111111111111111111111111122111111121212222222121221221122111111111112112111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111112122111111111222111121221221-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111112111111111111111111111111111111121211111112-122111111112111111111111212321111 11--111-1-1-312-24242222-3222342222-2--22-22-2332223332-332323D22222232442222222234324-121312D6R4331213112-122244242-1122223332413A2-33312212122-322--2223211221211212132111721-332I22321O25E352315BKB2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.100 MbtH/L9 domain-like
[ 429] ---9--------------------411437----------------1----------24-2-----LK -----------2--11111-1---1111111------------1------------------13-----------------------------------4745D12--2--------------------------51141---5---1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4----1111111-1-----------2--1-1---------------2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11-1--2-1-----2-122-------813-1----------11-12-413353Lo1-311-1----------------12-2------1IA-3-5G12121-132211614115---1-----------------------------------------------------------------------------------------------2----------761----------------11-11--141-H----212112222---1-1------11---11111153144----------22-2--1-11-----------------------------------------------------3 ------1-----------------------------------------------------------------------------------------------------3-oURLIW9DEB89EAIC9IBP*F-NCLAACADBFIG5CEBBF88L9MFHDGiTGJ343D366--E3------------------1----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.75 TSP type-3 repeat
[ 430] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--------------------------------------------------------------------26------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------ --------21-------------1--1---------1111-11-----------------------------------------------4----------------3--iccTeVVNPMJOKPaWMROc*Q-VLjMPNNSMJQJAOSKHOGDZOLDFU7EJ858434587567------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.66 4-bladed beta-propeller
[ 431] 11111111111111111111111121122212111111111111111111111111111111111111 1111111111111111111-11111111111111111111111111111111111111111111111111111111111121111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111-111111111111111111111111111-111111--11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111-1111111111111-111111111111111111111111111111111 22222221622222212222222222222222222222222222222222222222212222222222222222222-2222222222222222222222232224223243322232243232492323L3-3371222222222231122222422225522251822434233333H33333969B2864322222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.241 Ribosome binding domain-like
[ 432] 11111111111111111111111111111111111111111111111111111111111111111111 1111211111111111111-111111111111111111111111111111111211111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122222122222322211111122211111111111111112222222222222222221111111211121111111121111112221111211211212221211111111211111212111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 1111111-3111111111111111111111111111111111111121111111111111112222221221222221222222222221411111111111122411112222224232542254463HN2-7432141232322233123324231111612111112211122443d3333336891571211111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.41 Preprotein translocase SecY subunit
[ 433] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111-1111111111111111111111111111111111111111111111111111111111111111-11-111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 2311111173312222222222222222222222222222222222222122222222221221222212232223333322222233324222222222222336113133222323122322252635H2-4251116322211212221122222244133222234212223241H11122868G2631111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.39 Ribosomal protein L14
[ 434] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--772-fJG-11222232222242222222222224222222222222222222222233122--1-1--112------11111----5223233333213232-4S8NKZKTTMDBB9DFENJAQCm*M2TIdBBD9LEEJB8EAB6G97dDHGDM3CHDI96658AD8B65-33-------1122242-25867- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.14 Calpain large subunit, middle domain (domain III)
[ 435] 224242555555555542222212--------222222222222222222222266676652222--2 24624---------22222-22--22222222222222222222----------------532----2222------------22-22--2--2--------22--4---------------------------------222--46666644444222222744876522222222222222-12-662-------------------2----------2-------------------------------------------------------------------------------------------------------242-2-----2-2-2---2222---2---22222222-622--3-4--92-244222222--2222222222222222222222---------222-222222222222--222222222222222222222222221222222222222---------------22222-2222222222222426444422424444224242222222222422222222222222224222222222222224--------------2222222--333352---------------------------224422--224222222222222222222222--2-22422-22222222222222222222-2222222222222222222222442222222222222222222222222221-222222222222221222222222242-2-222222221213222----------4-44444444444444444----------222422222442445555555222222222-2222222--------6-22222---------------------24222242222--- --------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-1-------1--------------------3---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.283 Putative modulator of DNA gyrase, PmbA/TldD
[ 436] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 111111215211222122222222222222222222232222222232222222222222222222221223222222222222223332322224112222243513314332333222-322422522J2-2242232212222231322112132223422221326522223221I11121559I2451111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.75 Ribosomal protein S7
[ 437] ------------------------1---11----1---------1--1-11-------1-1------- 11322---------12211-12--23111111322211111231-1--1-----1-----11311123411---------112111121121-211----11--21111--------------1---1-211-2122222333111111111--11------11--11--------------11111441----------------------------------111111----------------------1---------------------------------------------------------------------187-346656763432355111-4132241123333636471222121113--111111111233221133333311111111111-33333433221122223332223333112222444422311111111322-2411111111111111111111111111111112122112211222222222222222222222222334441233133122222332334223214111111111345415315111231----343243285111111751--1---------------------112251213111212111111111112111131-1334212122232222222222222232-2222232222223222223333222223333333333333333222222232-32222222222211121111111116122211111111111111111111111113122222211322222111111111111211111111111211111111111111112223111111--------1-1-------------------------43344444442311 ----111-211-11111111111111111121111111121111111111111111111111111----1--111------1111111112111111111111112-121115221-111-111112114C1-113--1111111-111-11-11111111111111411311211111H1112131341111131111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.142 Nqo1 FMN-binding domain-like
[ 438] 111111----------1------11111111111111111111--1--11111111111111111111 221121111111111-111-11111111111111111111121111111111111111221111111222111111111121311111111111111-1111111111111111111111111111111111111111111111111111121111111111111111111111111111111111122121111111212122122211111122111111111111111-1111111111111111111111211111111111111111111111111111111111111111111111111121111111111111112111111111111111111111111211211111111122111222211111122223333333222222222223333333333313333343333311111111111112333333433333333333333333333333333333333333333333333333333332333331111111111211111111111111111111111111111111111111111111111111111111111111111121111111111111111111111121222222222222222222222222222111111111111111111111111-111111-1322111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111122222111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112222222222111111-111-11111111111111122222222221111 11--111-1-----1-11111111-11111111111111111111111--------111111111111111111111-11111111111111111-1111-111-1-1212131111111111-11-313811112-1-1111-1-111111-111111111-1111111-11-12111I11121111211111-1112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.97 An anticodon-binding domain of class I aminoacyl-tRNA synthetases
[ 439] -------------------------------------------------------------------- -2G---------------------------------------------------1-------2-------------------------11-2-1----------51-------------1----------------------------------------------------------------1--------111111-1-121112------11--------------------------------------------------------------------------------------------------------------------------------------------------------------6---2------------------------------11-11-1-----------------------------------------------------------------------------------------1111----------------------1--------------------------------------1---1-------1----------------G----------------------------------------------------------------------------------1-----------1---1---------------------------------------------------------------------------------------------------1--------------------------------------------11111111---------------------------------------------------------------- ---1--4-------------111--1---------------------------1--1--211--------------------------2--2----111---1----22-*AECBFJ9A69CEBKc7eEk*Q1WLo9BBAK8CVI9ED95H69L9G8CCMT969XG9DCEJ78KI-952G24433-122-3-2--1--- -----------------------1--------------------------------------------------------------------------------------------------------------------------------------------------8C222 * b.121 Nucleoplasmin-like/VP (viral coat and capsid proteins)
[ 440] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 4411222-82212222221122222222222222222222222222212222222222222222222212212222212222222222223222222222222222126242422222221222332325G312332221222322213232222322122222222223922322223F3323333452732343332 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.20 Initiation factor IF2/eIF5b, domain 3
[ 441] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 2211121183312222323222222212222122222212222222222232322222222232333312322332323232332333325232211222232335113121111111-11-216A-814T7-148111141165-11--21121113112111111522212113-21E11112646B2741111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.140 Ribosomal protein S8
[ 442] ---------------------------------------------11--1-12--------------- 1-1-2112111111445----2--24-----231113284121121221221232321--1-113327431---------1-------111--1------2-1-222-1----------------------------------2-11--------1-----------13-------------113-----1-3444443241334344224223433---451211111114211111111111111211111-1--------11----1-----------------------------------------------------1------1-21-----------1--1------22-----------------11--------242213-11121-11111111113-76566265-1--2112--311122-111---131331-11111111113313-22-------------------------------14-1111133443424111122533333113242-21-1--111222232-5-12112131111111112121112---111-11-1111--------1--1-2111---1-1111112222222221---1--11-2-12132-22332-1222221121223---1---------11-1-111111111111-1111111111111111111122--1111-111111111111112---11111-111111111111-----11-1-----1-2-1111---11111--133533211241-445435752333443441---------112111111221113243333333-------1--1222-----------------------------------------------114 ----221-----233456544356964433333344422222233388776887462323333221222112211321225111411215835421534118-424-342G123112221312133112191-111112112111112221211221351644511421172322111--1--1474945491-5233- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.5 Heme-dependent catalase-like
[ 443] 22724444444444455466655522222322435224666666545535555256556662444-11 244-1------1--21111-12--22111111233321232343----------------12321121211-------1454-2422244453344-1------1--1----------------23243324323333332221-1111111--11------11--221--1-----1-------11222-1-111111111111111-1----1111121-1-11111111111111111111111111112----------------------111--------------------------------------------598442322333222553321114352252163223365485854555211511114-----1242211-44645----------1---1--1--12--2------1----11-1112-1122124111111111----614------------------------------1161-222-23222242111222232222232242531--11221111111432--41---21----------534-6A5656534466526666555765565--681222222222222222222223322--211---1-----------1---------211---22-------112111-1111111111-1111111111111111111121211--11-111111111111111111111--1111111-1111---------11111-------------------11111---------------1----1111---------1---111111-----1111111111------22--------------21--------------------------5445444344231- ---1--1----2--11111111111111111-1---11111111111111111111111111111111-111111-1-11111111-111111111---1--1-11---------------------------------------------------------1------------12-----1----11---12111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.64 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
[ 444] ------1111111111--------43344324--2------------1-1111--------1------ 21121-11111----11----2--11-----12222111112-13----2311211-2----1-1-11321-----------1---11--------1---143323252--------------111111111-1133433---1133322233333444444334322433--3344-43-4---111---1-1111111--111111----1-11------231111111--11111111111111-111-1-------------------11-------1-----------------1111211111111-----------------------------------------1-------11---------1141221------1132--111111----------1-11211-22-111-221-1-111--2113244-3333331111111114111--31--------1--1--11-------------332-113----11111121111331111111112111112211-4221111-11-112-1232111-1111----11111-1211-11111----1-1-11111111111-------------------11-----221341134342222213-222212--2-2----112-1-111-1111111111111111-111111111111111111111121--111111111111111111111111111111111111111--1111-112122-1323---------------11111-111111111121212212222223231132121221-44444433221122222222------1-22--11----------1---------1---------------1-1--------1-- 11----3-522----444411121211------111----------22333333333--222-11-11----1--111112--------111411----3224111-2H29C988C32122223332315E21324232221232222222233295571---45566457--A4C786l8368787994877844546 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * a.99 Cryptochrome/photolyase FAD-binding domain
[ 445] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----337----P--2123133332223332333222123232233322332333332432221-----------------------------23-221111-1----6--IJWFHVGGFAHFDDRQJUHm*N-UDYFCCCNGBJD9DDFDFGBMFIGCF6686HHF4B9DB3563----E121--77DG284228DA83 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.65 Annexin
[ 446] 1111-11111111111211111124444444411111111111332333333321111111-1-2122 111-------------------------------------------------------------------------------11-11-2112111111111111111111111111111111111111111-11111111111121111111111111111111111-1111111111111111-11111111111111111111111111111111111111111111111111111111111111111112111111111111111111111-1111111111111-1111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111--111111-11121111111211111111111111111111111111111111111111111111111111-------------------1-11-111111111111111111111111111111111-1111111-11111111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--11111111111111111111111111-111111111111111111111111-1111111111111111111111111111111111111111111111--1111111111111111111-------------------------11111111111111 2211333-5221223333333333333333333333333333343323332233333333333323331333333331333333333333433333333323333215414223422221212135-312H2-2341222222211221221-22522213313222211111533146D4423453483452233231 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.75 MutS N-terminal domain-like
[ 447] 21-----24444441--122-1-41--1---1---------------1----1--------123---- -1-24---------23111-17--6-111114556737A8132212-1------1-----741-2--4341-----------122122-----1------------1----------------------------11134---4-2--3--1----1-----------1--1-------------11---1-1----------------11111----41-----111--1----------------------------------------------------------------------------------------------------------1-------1-1--112---11-1---------------3224-----1-211--13113211111111111---3----1222--11---11--21311222122322123--------1----122-------------------------------1112-1111-----11-111----111111---2354-12211--111-12-11-12---12----------111-816--------------------222222---------------------------2322113-321123333323623324455254--11112------22222213333333333-3333433333333333333224211122333323222332333432222232-222222222222--12-1111111121422111---1----1---11111-12213144443242433454222----------23333333322355----------------21-------------------------------------------1----------1- ----331-----4351111111142311111111111111111111111111-111111111111--1-2--11111----22212---11111111111123524-8838564556544555488584Fo7-A6E434474464354435449444348664953346A86445-11-----1113121111-33331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.106 SCP-like
[ 448] -------------------------------------------------------------------- 124-21--111---1------1---1------11113344---1121-1---211-12--112-2-2232------------------2211-211---22111211-1333333333333333---------1---------1--------------------------------------1-1-------122222111-1121111-1111111---11--22222221--------------------11-2--21--111---------111111111111221111111111111111111111111111111111-----------------------2-----12-----------------1-1--3222-------111--------------------11-11211111--11---1--111--121-111-11------------------1------------------------------1-21--444-2111221433-11--5444-41----------2--1---------------3---------------1---------6546-------------21---1-1-----------------------19----3-11--1-1-------------11-------------21-33232332222222-3232232222322222222222414625666656666666666125552254-987888187181--1-----------1D-1111211---------1111111----255151112211111B54----------1112-1--188111----1-----------------1------------------------------------------------111 --11333-933-3333333333333323333333333333333333333333333333333333333313333333323333333333334333343333333334-3356664462222223285252KI7-523222232255222223423233333133332333663333-12--223-154493431-33225 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.198 Secretion chaperone-like
[ 449] 222231222222222223333333322422222-2223433332424621232122222222222--- 1111332333321322222-2211222222222222333311111222211-3323-2--22122222222--------224111111------------1-11111-----------------1111111111131131---221111111111111111111111111------------11111---1-13333332313333331111113321111--111111111111111111111111111111------1---11-1-------------------------------------------------------235212222222-2-11---111----13--22332225-33322-22--1212111-----224215141111111111111111-54545556411-2111111111412112131221223222222222211111221-----------------------------11111-1222233434322222332222222232233321222222222222222222111111----------221-2244222423222-3133313132222224322222222222-2111111122222112212111-1-12222212222222222222----111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1---------111211-111111111111112121111111122221221111111111---------2222222222222221122222223----111111-----------------------------------------12---2---11-- ----111-----12111112221313121-11111111111111111111121212221222---------------------------1211111----1-1111-1--2132312111111222121372122311113111111-21311312112117131112111221111118-111111-21111111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.103 MoeA N-terminal region -like
[ 450] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2235665-G77-55544434444444444345444444445444444444444433444434444435-453444444444344444445744558444445466725C9BACBCAB89CAC9AEE7FCU*B5DCG7A86B99A879976CA8H9A8888HO776B8D69AEA764345q4444488AA4654565446 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * e.40 Cullin homology domain
[ 451] 11----1-311124-4-------422231411-1--4-12-3132-68--654---242--------- 2171-2---1-1-----33-31--1-32333--2-1--14-442---24--1111211--111--1-12---1112--1-61--1-1-2---22--2--7332--1911--------------3--4235-1C1111116-1--1AI4366R--111-----41136663-------------1--1------------------------------11---2----------222122222122122---1212-12--23111--13-2-------11-111112233332322243111111211111--23---444-21---------------11-------11113-17DB-281--21221-4B-211--1-57-8321-33122A-22----------2-23222151-14-33341222321332-111---11----22222222145--156------------2344-1942-22-6-32---31-1----233-211------1-------3-1-222--2311--212212-5--51--1-2-1-----C4261-13461251-3-11212533318451111--421311--1--4-1-22422145-22344-24132-43---21121----1--2---1---38227------46--1733332333622-23332243233311131143224369311213321411231121-112113--51112111-11---612212221-21-114-2-1---2232626---2-21122-76----1213-212-1431-----1----3-225574511121---11--1113434--232111----------7-1--------------------------2--------11-- ---------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------1-1---------------------- * d.298 RelE-like
[ 452] -----------------------1-----1------------------1------1-111-111---- 2221311111111111122-2211222222223222213511111-111111-211111122312234311----1-----13111111111-111---111111112111111111111111111111111111122--11111111111212111111111111111211111111111111111---1111111121311112111111211111111111------1311111111111111111111--1----1---1111----111-111111-------11111111111-----------------------11-11111111111111111111-111--1111111111211111-1-11111-111111111122211111111-1111111111-11311311111-11111211111122111222222222211111111211112221111111111---------------111112442211111233224333332222333313332444311111511111121212211213212222222111221211111111111111212311111332334112222222222222222222222222112232223122222222222222222222221-1111111-11111111111111111111-1111111111111111111111112211111111111111111111111111111111111121111121111122222123111111111111111122222222223222223333333332333111111111122242222233233222222222222221111111111----------1----------------1--------11-111-1111112 ------1-----2212222222323232223232223222222332222222321221222221122211111211111121111122225222224333233232-14-------------------------------------------------1----1-----------1222N2212114462322264442 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.144 RibA-like
[ 453] ---------------------------------1------------1---211--------------- 134-1------------22-2----122222-1----2-21122----------------112-1-11111111111112241-----11211111--------1---12222222222122231211112221122222111212----------------1--------------------------2-22111111111211121212222111752221111111113111111111111111111111----------------------1111111111112111111111111111111111111111111111113327444444454434334333433-12432133311213112121---314111111111112342112222211111112111-221222222121211111211111111111121111111111111111111142211111111--1111111111111111111-1111111111111111211112311111111121121111112224224333222371111212222222112322-4532122233222123422332533443113111111111111111111112111211232234324333443346424434233363--121121--11133222423333333333-3333333333333333334343222224444444455435344233333332-222222222222-1121111132232343311121111111111122212212322233333333433332235111111111133374344323434112151111111111141------1111111111-------------------------------------2-- ----122-----------------------------------------------------------------------------------------------------2------------------------------------------------------1----------1--11-----12112-12------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * g.74 Sec-C motif
[ 454] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1-------------------------------------------------------------------------------------------------------DbaViNhGDCCLMJm*CVDw*PRcN*LKDEQENLD4JEDBMHBYENPKL6A63A953478H227------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.73 CCHHC domain
[ 455] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111112111111111111111111-111111111111111111111111111111111 11111111512122222222222222222222222222222222222222222222222222222222-2222223332322222233323222222222222457112121411111-1-111551213A1-12212-15-11--112111-11211112212111112122112111P1112195A62731111112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.77 RL5-like
[ 456] -----------------------11-------1111--1111122-11-------1----2---1-11 132-3---111---21---------2-------1113-56-1-------11-121-----11--2-2241-1111111-------11111----------2---22-----------------------------11111----212111111111111-111---222111111111-111--1-1---113444444353552125313314254122112111111233-111111-1111111111111121121111112112211111111111111111111111111111111111111111111111111111---11-----------132----1-1--21-1--2111---21-1---1---1111--1---24847--15324111111111111-3212142313--411-42333522222--131----12411111111111111---------------------------------122-132255455742222155482222-48444856--5552343273615233-1111221111111111-54212--12--11112-1111211112333-1-11222-2121212-1111111-1--1---22-313-121211112-211112122122------2-------112-11111-1---12-121211-2111-1121222554233311111111111111111611-1112--122222222222-------------1-4-3---211-11-1---122222221114-22325433112-2-1-1211111111-1112222222222212--------1------------1---------------1---1--------1---------1-------1--- 11------42-2---24111222413122222211111111111221113213111111111---------------------------1524131-------111--2-9212222223143138-419K7-3442--21232212-2123-2231225-132432----34121221511112133B1341-52451 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.80 Tautomerase/MIF
[ 457] -------------------------------------------------------------------- 3332------------------------------------2---2---2----2--------2-2------------------22433-------------------2-111111111111111--------------------2---------------------------------------------222224244444444444222222444222222244444422------------------------------------------------------------------------------------------24122222222222223222---222--32223224432223322222--22332332----226233333533511221221222-5555535533323222334222222-3432124444222--------2222-263--------------------------------222232325444753444244325557262433222--223223222--242222222262-------222-22222-2222222333422222222233132-2-3333-3333333333333333333---25-222222222422252422242244442---222222122242233252332222233-2523422222325-22--2---3343344444444444444442231322372466666536565--2------2222--622-------------------------2233232223522222353---------2222422222672222233333335------233333332222222222--------------------------2-22222122-2-- --------------------------------------------------------------------------------------------------------------------------------------------------------------2-----------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.139 Surface presentation of antigens (SPOA)
[ 458] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4444776-F544766444454444444444454444444445444454444444444444444444442444444442554444454444844444444444455634C8J8HCDBDAA8E96AIFDFAJ*A1E9I5BBBA89966AC68968CAB9A7765767N9957C7AA6C554Q44346779A4964368863 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.25 Sec1/munc18-like (SM) proteins
[ 459] ---1-11111111111-1111111111111111112231111111111111111-1-----111--11 1111111111111111111-11111111111111111111121111111111111111111111111111111111111-1111111122221211-111111111111---------------22222222222111111111111111111111111111111111111111111111111111111112211111111111111122222211122212221111112111111111111111111111121111232323222111122211112221111111111111111111111111111111111111111122-11---111-1-1222211111-2--1112133132111111112-11111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111---------------111111111-111111111111111111111111111111111111111111111111111111111111111111111111212111111111111111211112212112211111111111111111111111111111111111111111111111111111111111-111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111---1-11----1--111111111111111111111111111111111111111111111111111111111111111111111111111111--------------------------------------1--111111221 12--112-311-11322222222222222222222222222222221222222222222222222222222222222-222222222222322224222222-343-22253322312222222432315I2-3221222211211221222121221213-12211211A21412111K111112-332122244222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.92 Carbamoyl phosphate synthetase, large subunit connection domain
[ 460] -------------------------------------------------------------------- ----1----------1111-11111-1111111---1111-111----------------11--11--11---------111--------------------111-1----------------11111111111111111---1-111111111111--111111111111111---1-11-----------1---------------1111-1-------111------11-------------------------------------------------------------------------------------------111111111111111111-1111111--111-11111--1-------1-------------1111111-11111------------11111111-1--1--1111-1-111-----------1--111111111111111111111111111111111111111111111---1--111111111111111111111111111111111--11111111111111111121111-------1111111-111111111111-111111111----11--1111111111111111111111-11111111111111111111111111111111111--111111111111111111111111111-1111111111111111111111111111111111111111111111111-111111111111111--1111111111111111111111-11111111111-11111111111111111111111111111-111111111111111111111111111111111111111--111111111111----------------------------1--------11- 45223331DJ3222211111111111111112111111112111-111111111111-11111111111111111222221111111113221222222221-5451374867545731A63445G594D*5-A97444655446244254316454455BE343U4346633442334*44433A7GD1964543335 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.271 HSP90 C-terminal domain
[ 461] 111-112122222223-21111114112-233-----------133---11-------131111---- 23618---11----13222-21--2412221232221134-41214---31-343--3--313-1-45441---------A5411133------------1--1314------------------1--1------3333311-414223222-2--------1--22242------------64333---1-1----------------111-1---111----------22-----------------------------------------------------------------------------------------------------------------------------4--C-2---------3-12111-----145355223223322222222224-67547848-2--22233444454447--14142322323--------53311221-----------------------------11132-111134444534222222563333344384342132233422143612143-1-2262-----------24-1----------------1-1-31443432-12----222212---------11--3--44-1112-2-11312211211111222112----1-2------11212221112122111-11-111111111111111122211---11111211111111125-11---1--111111111111-------------2-3231111--1-----111----------1-33431122111111222---------1-1122222212122--11111111------1-------------------------------------------------1---11-- ----11------11335533333554333333333322111223332244355634332333---------------------------4825213----6-2211-14221211--1111-111111-443-111111111111-1111111-1--11--311111112-11412223P3322355753322233224 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.176 Oxidoreductase molybdopterin-binding domain
[ 462] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111-111111111111-1111111111111111111111111111111111111111111111111-11111-11111111111111111111-111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 11111111422122122212122221222222222212222222222222222222222222222222222222222222222222333232222522222-244511312121112112--2-331211E4-126-11-11-11-11-1-1-11211124111211211111122121E11112832I2731111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.28 Ribosomal protein S19
[ 463] ----------------------------------------------------1--------------- -2212---------21111-12--12111111322211-----131-22---221111----1--11143-----------31----15212-311---111131-1-1--------------1---11---11---------3-5332334113322222223243432222221221222-----113-123333352423335532111124351122123111111542--------------11-112-1--------22-----1-2121111111111111-----------11111111111111--111---1-4411222222213--2---1111-1--11--111-31------11----2-14222-----334443222333333333222333-442343323511433266457644331114322234224------------1332------------1---122---22------111-1-----2332322222222212222133522111--1-133-11-31--3112-1--3--1--2-211-222231-1-15111---11-1-1111-----48-4------1-----1----------1-112223-2---131112212321211132113--1-1--------32222233332322233-3333322333323333332222221113333333333333333333222331-222222222222--12-----22223-11122222212322222233333431111--12--1-1-12221---111111111-1113111112232311112112221-----7-11----1111111111--------------------------------------1- ----111-------------------------------------------------------------------------------------------------------74544743331232332426E3-234-3323145413321422334233223111222111--2----1------1--1-----1---- -------------------1----------------------------------11----------------------------------------------------------------------------------------------------------------------- * d.65 Hedgehog/DD-peptidase
[ 464] 11111111111111111111111111111111111111111112212111221111111111111-11 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111121111111111111111111211111111121111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111-------------111111111111111111111111111111111111111213211111121111211211111111111111111111111121111111111112111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112122111111111111111111111111-1-111111111121111111112111111111111 1111111-43411111111111111111111111111111111111111111111111111111111111121111111111111111112111112111111212118121112122322223232516I3-4252222211432133213252111112-32112211211111222O21233A5671433532322 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.86 Phosphoglycerate kinase
[ 465] 11-----1--------1-11111-------11-------------------------1--1---1--- 12313111111-1-2--12-1111121-1-1112222232331-4412111-333113--22423233342122211111211-----1111-111--------1-------------------111111111-132221---11---------------------111----------------11--1-112222222232222221---122221--2-1111111121111111111111111111111113112212111331111112222222222222111111111111111111111111112221112222-33-333332341211522-13111-112321-22-211-11-111--211--2222-----1-3112-12212222222222222-11311613-31-333344433344321111121-11-122222222212221213-----------------------------111212233134354542333333344444244433444--333322223242211121111531111111---211111-1-11221112-212121211333321--122-1----------------1-----3311412112311111-1211112122142------2------33112322222222222-222222221222222222233311122333333333333333312222212--111111111111-----1--11211-271222212111111---111111-11112255653432433332222----------122511111442221111111111-------1--------------1--------------------------------------11- 11-1113-8421121------------------------------------------------11111-11111111-11111111111121-1111111--1222-342211111111111112111--1--111111-1-11112-111-1111112--1--21-------1-13124---3-3224-221222222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.116 YbaK/ProRS associated domain
[ 466] -------------------------------------------------------------------- 8OV2H---------A7744-48--5D444446BABABAMM19287I16343-556322--9A9-95GCGF----------1-1-------1--------4B778K7I2E---------------11-112--22-23323---L62-4111---11-------11111--------------G6E221--3-AFFHFHJHK5JKKKHI9DA838MJO244C843------CL2---1-1-11---111--111----------------1----------------11-----------------------------------------------1--------------9----12---------------G-6---------11-11--------11111111111-------1-122-411122223411--1-111-----1-2--------1-----1-------------------------------------1111133321-----222-------212------11----1112222-11----12-------------1-21---1-11-----1-1----------11-11-----------2--------1-----1---2-1-----1---------------------1-1-------1---1-------------------------------1111--------------------2------------------------1-1---------1-1---------------------1-----11-1111221-11---------------------------------------------122------------1--------------------------------------1-4 ------------------------1--------------------------------------------------------------------1-------------11--------------------------------------------------------------------1----1--2------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.213 DinB/YfiT-like putative metalloenzymes
[ 467] 111111111111111111111111----1-11111111111111111111--11----------1111 1111111111111111111-111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111122211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211----------111111-1111-111111111-111111111111111111 34111222722222311112222222222222211121111222221121222212212212121222122-2122222221111121214112211111112213223122221121-11212232629B2-41112221121-112-111221121132122132331222211131922213425213222-4111 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * d.181 Insert subdomain of RNA polymerase alpha subunit
[ 468] ---1-12222222222--1-----------1----22-1111-------11111-21----------- ----2---------22222-42112222222222222122-22211--------------111-2112121--------1--1--1--------------2----12---------11-----------1---2-2111-1111-21311111222--1--121122122------------11111---82211111111-11111111--22111112----------11------------------------------------------------------------------------------------------1-----------1-1--21-221--3-----423-3-2---1-1-11-----11111-----222221113322311111111111-22322322131-21122232132112-1-3331112223---------11--223-----------------------------1-1---222211222223333222333233224232222--22211212112-31-1------------------1-2----1-2-2-11--1------1-11-143-11--------------------11-2------1211-1------------------11--11232------22221222222222222-2222222222222222222233231111111111111111111222222222-111111111111---------111111233---------------1111111---1111-11221-1221-111-11111111----22222222222--------------1-1-------------------------1--1------------------------11-- ----222-542-22423515434535411-1-1221433332323311456866444741111-------------------------11223325---113122--3D3A9B6872332324366453CP4-6442132532342322243352444431146533A5232353322382222175774A54223324 ---------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------- * d.269 Gamma-glutamyl cyclotransferase-like
[ 469] --------1111-1-----------222-2-------111121-2131-3213--------------- 311-2331221--2---11-12--2211111-2--1134---12--131331-1-11-------2--1--121119541251-11-1-3232-1-1---4211---2-2--------------623822622615-1112-1-2--11-132----------11-2-21-------------11-11----21--1-1----1---1--------11-2-1-1-1--------111-11111--1112--1--2----1-22111111--4---1---1-------1111111111211--11----1----133---1111-11--111-1---1213---11-12--41213-75331311-------351--4111-631531-232112335411111111113-33-12132142-4443-13-3-1213-21412-4-----333333331-23-111------------1-54-1411-11-3-3---3-1-11-1-111212-------2------14-11-11-2--12132-174145--4-1-1--346454562-51224345176223111--539-3824322211-22---1-1--1121224311222-1321-1223--4211-213332-3-11-4--111---12-3------231311-1222121211-211122212222111111232323781232121231121211211111111--423223323333----5744431-211--211111--112-3353---1---23134221211221122421121----2----1-31-1--1--111-1332322211111--1-111111--------4-2-1--1-1-1-5------4-----------------31-- ----411--------1--------1---11-1--1--11111-------1342411--1-------------------------------E----2-----------2-54111111-11111111-11151-111111111141-121112-111-121111111111121112-12-----1----1--8--1111- --------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------- * a.265 Fic-like
[ 470] 11-1--1111111111-1111111111111111111111111111111111111-1-111-1111111 112-311111-11112222-221122222222222212441111-1111221122111111111112222-1222111111121111111111111-111111111211---------------11111111111-----111--1-11----------------------------------11--11-1---------------1------------------------1-11111111111111-----1--1--1----11----1--11111111111111221111111111111111111111111112221111-1-11-------1-1-11111111---1212-1--111----------1121-3222-1111111111121111111111111111-11111111112-1111112121223132321333321241111111111111112-----------------------------1222211111323333232222222333332332211111122211222222121211111222111111111111211221221213112-222222223--1-2321111111111111111111112112222222211212212322222222222222223--1111111111122333322222222222-2222222222222222222222333423333333333333333322222222-22233333333322131121111-11131222222212222222222222211111133333423122311332222222222122222222222233112222222222221111111111----------1------------------------------1-1111111 ------1-----1-21111111112111111111111212222111121-2-1-1-11-111111111-1111111111111111111122-12121111122123-21-----------------------------------------------------------------1211171111156561632111112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.130 Chorismate mutase II
[ 471] 11111111111111111111111111111111111111111111111111111111111111111211 1211111111111111111-1111111111111111111111111111111111111111111111112211-111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111122211111111111111111111111111111111111111111111111-1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 1111221-31111111111-111211111-1111111111-111111111111111111111111111-1111111111111111111112111111111111222123133332512222222232223D212221222221221222222124322122222122322222122222I222-222331222223222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.203 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
[ 472] ----22111111111112-----1211--111--1--------13121-1111-1-111111111111 --11311111121212233-3111123333311111111112111111-111--11-2--11112231212111111---1-1112-1--------1---11--31---11111111111111-11--1---12----11111-1---122-1-------------1-1--------------------------------------------1-------------------1111111111111------1-211111-111211111-111------------22---------------------------------1---11-----------1--------1------------------------2-2---1-----11---1111---1------------11211111-1--111-22211111-------1-------11111111111---1-------------111111111-11------1-2--111112111122222311522222222122321--221-11111-111-112----12--111--112211-11--1-1-1----1121-1-21-1111121-1----------1-1111111--1122211--112-----1221--3111--23---1---111-------12112-12112222212-112211211222122222122211---2121222222212112211122121----------------------222211221111112--------1-----------1-----11-11111---------------11-111111111111111111111111------1111--------------------1-2-1112----21111-1-------11-- 22--231-411-1134497477567563333331113222222333543343546693333322222212232231313322222211156546632222182424-141L2351313333332723635D3-335233353343-33323313322344427345594C44731---2----228F6A57N--3131- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.17 PEBP-like
[ 473] 11111111111111-11111111111111112111111111111111111111111-11111-11111 ----------------------------------------------------------------1-----------------------1111-111---11111111-1--------------1---------------------1111111--1111111111-11111111111111111--------111111111111111111111111111111111111111122111111111111111111111-1-11-1--1111111111---1221111111111111111111111111111111111---------111111111111111111111111111111111--1---1-1-11111-11--1----------------------------------------------------------------------------------------------------------------------------------------------1-------------------111---1111--------1--------------111-111--1-----111-1111111111---1-------------------11--1--11-111111111111111111111111111-------------11111111111111111-111111111111111111111111111111111111111111111111111--111111111111--1------------1111111111111111-1----------1111111111111111111----------11111111111111----------------111111111111111111111111---1--11----111--1111-11111111-1-1 32233331933223333442333333333343333323233333332322333313222222323533233323333333333333222353333333332324451364544334553G44657E3646P5-56964338345454834554D4644456534433332633433334R33333666A4773334322 -------------------------------------------------------------------------1---------------------------1--------------------------------------------------------------------1---- * d.64 eIF1-like
[ 474] ---------------------------------------------------------2---------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---1225-C62-4263333333333123323333333333333333333332333333332333233413243333444433333333324232222222222443-652KLNEFDFB7BCBC8MJ8H9d*F2HDP89C8HCAGB7CB8BC88J9A9A9AAE9IAY6C6969D9E----1-----24573451178771 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.132 Supernatant protein factor (SPF), C-terminal domain
[ 475] 1111111111111111112222211-123222111111111111112111112111111121111111 122131-22221-1-1111-11--121111111111-11122562211111-1113-1--323-2332231---------11211111------------2-1-4-311--------------111-1-----1-2221111121222122111--------11112222--------1---3432211-1222222244424444442222223442221223------2211111111111111111111-------1-----11------1--------------11111111111-----------------------11-212222222-2-1-222222122--311-1222-11221111111-11112332-1111111111112111111111111112-22322122141-23323313351111111-2211112----------11111121------------------------------1121--11-1132221-111122111111111111111--222-1-1111222----1--11--------1111221111211--11--1-11112111111111311----------------------111--11111---11111111111111-1111-11---1111------112221-1111111111-111111111111111111111111---111111111111111111111111--111111111111---11111-11111111----------------1---1-----1-11-11-1-111111---2111111111---1-----1------22322222-------1----11--------1-1-------------------------122231111111-- -111223-211---223431232212311111122212112221-111344333112123332121211-112-1111111111111111333121111-111-1--1469252732313313234231BK4-442121232452242124313143244524442-2322--2114123132314426562121221- --------------1----1-----------------1----------------------------------------------------------------------------------------------------------------------------------------- * d.61 LigT-like
[ 476] -------------------------------------------------------------------- 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 33--112-511-11111111111111111111111111111111112111111-11111111111111111111111-1111111111112111112111111111-2613432223222232264151DK3-536-222222232222-32232222311432211222112432222M3332143441232321111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.117 Obg-fold
[ 477] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11----1-1---11222222222221211-22221212222122223322222212122121222--2-2-122222222-2222222214222222222-2-12-11-1WAFBBLHAADE9B8zP8EAb*O-JIJA8CCJADJ-BCBABHCBJDTEDQa*f4ZX87EC7C3441--------------2--------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.52 Inhibitor of apoptosis (IAP) repeat
[ 478] ------------------------11121111111--------2211211111--------111--11 1121211111111111111-111111111111111111421222111111111111211111112222111111111111111111111111111111-111111111111111111111111111111111111111111111111211111111111111211122111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111112121111111111111112222111111111111211111111111111111111311111111121111111111111111111-1111211111112111112111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111112111111111111111111112111111111111111111111122212111111111111111111111111111111111111111111111111111111111111111112122222211111111111111-11-111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 1111111-5211111111-111111111111111111111111111111111111111111111111111111111111111111111112111111111111211--612111-23222112222222352-2341212222312112121232222211111111121111122322G2222244451622211111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.73 Head domain of nucleotide exchange factor GrpE
[ 479] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 1-1111115221112111211111111111111111111111111111111111111111111111111111111111111111111112211111122112154311212111-11111--2123-2-3D1-1121-11111121111121121211111111111112411123221I1111163981341111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.53 Ribosomal protein S3 C-terminal domain
[ 480] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----65--------2----------------------------------------------------------------------------------------11---14*XRTNMKF9E9DIDNMBMGP*L-KKbADABLBHOE9EBC8I88OHPLJN8LY87989E79A58R2---1--21----------112-1- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.141 Frizzled cysteine-rich domain
[ 481] 11---11111111111-11111111221121---1--------1111-1-1-1-12111111112-11 1---121111111111122-211112222221222211111---111111111211111111-11111111-111111--1-11122111-1----1---1111111-1111111111111111-----------111--32312111-111----------11-------------------11--11-111111111111111111111112111111111111111111111111111111111112111-1-11-2-1-11111111111111122221221111111111111122222222222221111111111---1111-111111111--11111-1112---111--1-111111--11123-111111111--1--111-1---11111111111---------1-11111111-111----111--1-----1-1111111111111-1111111111111111111111111111111111111111111111111111111111111111111111112111111111111111-1111111111111111---111-111111-1111111111211111111211111111111111111111111111111111111111111111111111111111111--11-111-11122121222222222222-222222222222222222222222222222222222213222222222222112223222332221111111111111111211111111111--111111111111111111111111111111111111111111111111111112112211111111111111-1---------1--1-11111111---11-11111-11111---1-1111-1111--- 11-1111-311-11111111111111111111111111111111111111111111111111222222121222222222222222111111111111111114231151223222111111111-211281-11211111-111112111112111111643111-111111121111H1111121241112231117 ---1-1-1--------1--1-1-11-----------11-1--------------------------------------------------------------------------------------1---------------------------------1---1-----1111- * a.98 R1 subunit of ribonucleotide reductase, N-terminal domain
[ 482] ---1--1111111111-11111121--11111222222222222222222222222--------2-11 --22311111212122222-221123111112222223332222122-2111111111--222122322221111111-121222222222222------1--11-121---------------22223333323111222222222212222222111111222222321111111111111112222-21111111111111111111112111111121--11111133-1111111111111111111------------------------1--------11111-1111-----------------111111111-21-22-------1-12122----2-2--211221122222-2211-2--1-221111-----222222223222222222222222-11111111222-2112222222222211122222222221111111111111323-----------------------------211111211112333423-1112222111111322222211222212223121212231212111111111111122-2222222122222-2222222222222-3221111111111--1-------11111222211221-2121111111111111111111---1111--1--111211211111111111-11-1111111111111111222121111111111111111111211111111-11111111111111-----------12222111111-111-1111111111111121112112112111121112----2---211111111111111111111111111111131222222--------------------------------------2--2-222222- --------------11111111112111111-11111111111111111111111111111112222112212122222222222211113312211111111111--1----------------------------------------------------------------1-2112H1111121211222221113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.270 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
[ 483] -----------------------2411--3------11--------2--2735--------------- 33525---------11144-41224144444411111-1-1---1-------1-1-----232-142264-------------111111112-1-11--2223122211-------------------1------11111---121212111-----------1--11--------------111--221111111111111111111111111111122211-------11-------------------------------------------------------------------------------------------1-1--------------11----21--1----11---1----111----11-111111111211112111111111111111111-111111111421211112231223111111111111111222222221223211111-1111111--1111111111111----11111122223433324433333344333323443443422444232222333323274222222222222333334111121121421111343343423112115141221111111111111111111113333331224423233333233333333333332-22222------32222322443222222-42222222224232222232223222222222222222222223222222222322222222222122322222222242233222222222222332223322322223222234332222223334222222221333322222233433322222223222222122222221111111111---------------------------1-1---------1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.125 LolA-like prokaryotic lipoproteins and lipoprotein localization factors
[ 484] 11111111111111111111111111111111111111111111111111111111111111111-11 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111---1111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111-1111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111------1111111111111111-111111111111111111111111111111111 1111222-311111111111111111111-11111111111111111111111111111111111111111-111111111111111111111111111111111111431131112112111122111151-1211111111111111111121122112-11111112311212222G2223333371442232222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.36 Signal peptide-binding domain
[ 485] 11----1111111111--1-1---31111121------------------------------------ 2451111111111123211-171122111111433411111111111111112111111111111121111------------1----------------222222312--------------11----------11111---11132211111112122222211534211111111211211111---22222222222222222222222222212232111111113211111111111111111111--------------------------------------------------------------------------------------------------1---------------------1-4122211111136444412123233333333333-336436345521433265546576211112133333222111111112221221-112111111111111111111111-111111112-1333553333533443333655553344557661155532222213161421322121-------1235241-----11-1-111-1-1-1111-223222---------------------------2211132151221112223212222211221211-32-111111111111111111111111-1111111111111111111111111111111111111111111111-111111111111111111111111111121112111---------------1111111---2133332322222223111-11111111-1--4-----221113322222222111111--221111----------------------------------------------12-- -4------1-----1--1---------111-11111-------2-1--------131-----1-111---1-----1----------------1---11----111------11111-----1-21-1-18--11-----1--21--------1-1------11-112--n-111111----------2-11--2--1- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.25 Cytochrome c oxidase subunit III-like
[ 486] ------------------------11112121-----------1111111111--------------- 111-------------------------------------------------------------------------------21-11-111111111-1111111111111111111111111111111111111111111111211111111111------11111111------------111111111111111111111111111111111111111111111111111111111-11-1111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111112112-11111111111111111111111111111111111111--11111112111111111111111111111111111111111111111111111111111111111111-------------------------11111-111111111111111111111111111-1111111-11111111111111111111-1111111111111-11111111111111111111111111111111111111-111111111111--31111111111111111111111111111111111111---111111111111111111111111111111111111111111111111111111111--1111111111111111-11-------------------------11111111111111 2211222-4211122223322222222233333333122212232321222222122222222222222222222221222222221111222222222222323113114731224-111221563516S3-63712318123212222222823322141132221123413342227322121112321-221223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.292 DNA mismatch repair protein MutL
[ 487] -------------------------------------------------------------------- 3331423333321344534-341144333334444444441412743334344443331132423254442-----------3-------2--1------1-1-2-112--------------1-----------11-1111111211111111111111111111111111121111121111111---111111111111111111211111111111111111111122111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-----------------------1----1--113311111111-------3-21111111111111121111111111111111-1-1111111111111111111111111111111111111111111111111111111111-1111----1-1111111-11-1111111111111111111111111111111111111111111111111121111111111111111111111111111111---111111122112221111113333111--------------------------221111111111111111111111111111111-11112------22112222222222222-1222222222222222221222221112222222222222222222222221-111111111111---1-----111111211111111111111111-1111111111111111111111112111111111111121111111111111212222211122221111----------------111111-1111111111111111111-----------2-2 ------1-------1111111111111111111111-11111111111111111111-1111111----1--1-1------111-1---111111-21111--11--16-4322221-122122341323D2-324-21112242-22112112155-3----221-------111212E111-2422112112----2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * b.113 N-terminal domain of MutM-like DNA repair proteins
[ 488] ------1111111111--------32233223--1------------111111--------1------ 11111-11111----11----1--11-----11111111111-11----1111111-1----1-1-11111-----------1---11--------1---132213242--------------11111111111123322---1122212222222333333222322321--1122-21-2---111---1-1111111--111111----1-11------221111111--11111111111111-111-1-------------------11-------1-----------------1111111111111-----------------------------------------1-------11---------1131111------1111--111111----------1-11111-21-111-111-1-111--1112122-2222111111111112111--11--------1--1--11-------------111-111----11111111111221111111111111111111-2211111-11-111-1121111-1111----11111-1111-11111----1-1-11111111111-------------------11-----111231123231111112-111111--1-1----111-1-111-1111111111111111-111111111111111111111111--111111111111111111111111111111111111111--1111-111111-1212---------------11111-111111111111111111111112111-22111111-33333322111111111111------1-11--11----------1---------1---------------1-1--------1-- 11----31522----443411121211------111----------22333332333--222-11-21----1--111112--------111411----3254111-1E2BC988B32121122332214C21223222121231222222223275571---45755442--B4D877j63568969B4987644542 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.28 Cryptochrome/photolyase, N-terminal domain
[ 489] ------2223333242--------2---1--------------------------------------- 2-4--13233321211111-11--1111111-111121221---212--11-233-12--1111213-1-1233342311--11------11-1---------1--4-1--------------------------11121----1-11----11-----------13311------------111---1----44444544355566431112-446---11--------33-22222222222222222232242-1222223433-1324353---1111---------------------------------------1-----1111111111-1---11111-11-----11-----1--------1--9433--------1-1--------11111111112-------1--3--433233243353--21-1312122121---------2221-1--------------------------------1--------1111111------3-1111-11-1--------2--1------2------------------------------1---------------------1-------1111-1----------------2211-2--2-1-111112211112132121-------------31331123332333333-32434333333333333332223222-232222222222222243323333--1--------------------11-1--111--------------1------1-----11111111-1111-231-------------2-----1----2244444333------------------------1--------------------------1----1---15-- ----213-7421--22325222242542222222222222222222333323333344223321211311111-211111111112213123322211112-3-2--3S8755433-------------------------------------1----411123315335222351542P222234899464-322113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.70 Nucleoside hydrolase
[ 490] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--1--2222222222-2222222222222222221222--11-222222222222222211112222--1111111-1111---------------------------------------------------------------------------------------------------------------------------------------------------------------- ----126----------------------------------------------------------------------------------------------------3--CTOOURHDAA9EKCbR7TFu*S-QMR7D9CR9JPIAEEC9H98UFHHDG67565494B8775894--------1--------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.37 A DNA-binding domain in eukaryotic transcription factors
[ 491] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3333645-D55344444444444444444444444444446344434444444444444444565443146455645-443656467654744434544444478735749788A5B6566677BD3C6H*B2A8D5666677777755786498A87734E54542537A33533656*55536FAHG4D93454444 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.71 ERP29 C domain-like
[ 492] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ---2363-----45533343333434333333335323333333332433434333233333333333-34-23323-3332333-9995H63A793333653DDH34A4AABAKDC8563888HF7I5Ll85B8E45568788867845B54K88858-CP4B573G4BC-2453335H65445HA5S3u64833339 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.59 PAH2 domain
[ 493] -------------------------------------------------------------------- 1111411111111111111-12111111111112133232111111113111111111111111111151111111111111111111112122111-1111111111121221111221111111111111111111111111112111111111111111211132311111111111111111111112222222122123424122222322322312212221224222222222222222222322112111111111111111121111112111111111111111111111222111111111111111111121111222123133212432121211112211111211112111122111111111115112111111121111111111111112-112214312112111111111111211111111111111111111111112111111111111111J11111111111111111111111111111111112111111121111111411111112211212131111111121111232211111112111221111112111122111111121111111111-1111111111111111131111111111111111111111111111111111111-1111111111112113211211121232121131211122211111121112113323122112212212213111223211211111111311111111111111111111111121221--132131122121111112221211121131112111111111111141111111111111121111111111111111111411112111111C111-11121--111111-1111111121111111121 -------------2-----------------------------------------------------------------------------------------------------------------------------------------------------1-----------1------------2-----1---- ---------1-------------------1------1----------------1-----11---------------------------------1--1-------1--------------------1----------1---1-11--1-----1-11------------------ * a.81 N-terminal domain of DnaB helicase
[ 494] 11-1-11111111111-1333121111111111111111111111211111111-------111--11 1131211111111122222-221122222222222223332333221121111223111122222132221--------11111111211112111---22222211121111111111111112212222211211111---21211111111111111111111222111111111111122222---22322222212222222233332322222212112222222111111111111111111111-------------22---------------------------------------------2---------11111111111111111111111211---1111121111-12111-1-111121-11-----112222112212211111111111-11111111111111111111111111111111121111111111111111111111111111111-111111111111111111111111111111111112111111111111111111111111111111111-1111111111111111111111111-11111111111111111111111111112111111111111111111111121111111111111111111111111111111111111-11211------11111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111----11111111111111111111111111111111111111111111111111111111111111111111111111----------------------------------------------11-----1112 1---11--31--11111111111111-11111111111111111111111111111111111111111-1111111111111111111111111111111-22111-14-3221-1-211111142141661-31311114111111-1-11111111111-111112111--1-1221211-3221151121111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.113 HemD-like
[ 495] -------------------------------------------------------------------- 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111-1111--11121111111111111111111111111111111111111111111111111111111111111111111-1-----1----1111111111111111111111111111221211111121112222221111111111111111111111211111111111111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111-111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111121112222121111111111111111111111111111111111111111111111111212111111111111111111111111111111111111121212222222222222222222--11111--1---11111112222222222-2222222222222222222111111112122222222222222122112221-111111111111--12111111111121211111111111111111111111111221111222222222222211111111111112111111111111111111111111111111111111111111111----1-11111111111-111111111111111111211 ------1-------1111111111111111111111111111111111111-1111111111111111111-11111-11111111111-2111-11111---111-131112111-112111112112141-112111111111-121111-11--121-11111-211-1122211111111111111141221112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.39 YebC-like
[ 496] ------------------------------------------1------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2211BC6-622-3223332333323333333333333333333333433332333333333333333342343323343333332322225232222222133543193BBFDDGDGBC69AAASFBDAY*B2GBL6A88BBAE75A9A6B65IAA78B47356745645A4868-111F21212324432233CEFE5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.222 VPS9 domain
[ 497] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----BA6-----66511111111111111111111111111111111111111111111111111-11----111-----1-111111111111111111111667-F-2GHKEOGMEG9CDBBaTEOEl*F7QFN9EEDDEEFBBBCCBECBLEEAAA6CC37696B89D5B971-------------1--1-2432- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.55 Rap/Ran-GAP
[ 498] 11111111111111111111111111111121111111111111111111111122222121111111 --1--12211111111111-1111111111111111-122----2-1--11-----1---21-1-11----1------11112-----3332-111---211211-111------------------1-----1-11111---1------------11111---------------------111------12222222121122222114222221111111111111113111111111111111111111111111-11111111111111111111111111111111111111111111111111111211111111-11111111111111-1---11111--1-2---11-----1--111--1-1------11111-11----------12222222221-22322222----1111-----1--1------211-1-1-11111111----1--1------------------------------11-11111-11111212111111212111111122222-111122222322121231----111111111---12-1-1-111-111-------------111111--1321111111111111111112-12--22111-111111222212111111111111--1----------21222112222222222-222232222222222222222133222333233333332323322222222--222222222222---1-----1111--1122221111-1111---22222221112-2222222213333111122212221211222111112211111111111111111-1--------------------------------------------11-11------1-1 ----111-42-21111233222222221111-111111111111113211437322111111-12112113312137233211111-1411121111111311112-1613111-21--1-21-11-11221-112-1--1111--2-1-1--311111---16111211-1431-221E21121---13--2211112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.88 Glutaminase/Asparaginase
[ 499] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------MTYQcPAIBCDFKFTUBSH**I1VLdCFCCWGGLG7GFB7JBALGMJKI8D-5FE72745E5923------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.76 Hormone receptor domain
[ 500] ------1111111111-1-----1---11-11---------------------1-------------1 1211111111111111111-12112211111222221111111111111111111111--22112111111111111111111111111111-111---1212212111-------1111111111111111111111111111111121111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111-111112-----211131111111111111111112-22112121311-11111111111111121111111111111111111211-111111-1111111111111111111111-----21111111-111111112222111122222211111111144121222232421113211111-------1122211111111111111111111111113333422211111-----1---------2111111222112412232333333433333333333--12222------22222222222222122-2222222222222222222222222222222222222222222212222222-213123313222--11222222222211131111-111111111122222221113211112222212224222111111111122232222222322112222222211111111111111111111111-1-------------------------11111111111511 -1----------------------------------------------------------------------------------------------------------3------------------------------------------------------------------1111F111212136-1111----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.204 Ribosome binding protein Y (YfiA homologue)
[ 501] -----------------------111111111-11-----------1111-----1-1111-----11 1111111111111111111-11111111111111114111113211111111411111111251111111111111111112111111234414311--112112111111111111111111111112111112122111111112313411111111111111111211111111111111111111111111111111111111111111111211111111111111111111111111111112211111111111111111111111111111111111111111111111111111111111111111111111111121111111111121221111112111212111212221211111111111111122222121112111111111111111111-111121211111111111121111211111121111111111111111111121111111111111111111111111111111112111111111111111111111111111-113111111121111111131111111111111111111111111113113113112321111111111222111112111111111212111111111111111111-21111111111211111121112111111211-11111111332111111111111-1111121111111111111111819B1111112111122111211112221111111111111111111111111211113111111111111111111111121111111112111212111111111111111111111-1111111111111111221111111121111111111111111182A21-111111211111121111111111111111111 11--11-11----------------------------------------------------------------------------------------------11---11------------------------------------------------1----1-1---------3--17111111--3-2122-121- ------21------1----------1-------------------1--1-1----------11121112--------------------11-----1-----------------------------------------1----------1-1--------1---1---------- * e.13 DNA primase core
[ 502] --------------------------------------------------11---------------- 1111111111111111111-11111111111111111111111111111111-11111111111111111111111111111111211111111--1--1111111111--------------12211111211211111111112211111111111111121111111111111111111-----111111111111111111111111111111111111122222211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1--122111111111111--11111112111111111211122111111111111111111-11111311111111111111111111111211212211111111111111111211111111111111111111111111111111111111111122121121221122222212123111111222112111212111122111111111111122111112111211221111111111133111111211111111111111111111111111331111111121211111121111111111111-1111111-11111111111111111-11-1111111111111111111111111111111111111111111111111111111111111111111111111112223121211111111111111111111111112111111111111111111111111111111121111121211111111111111111111111111----------1----1-1111111---11111111111111111112111 11--111-311-1121111111111-111-1111111111111111-111111111111111111111111-11111111111111111111111111-1111122-1212-21111111-11131121252-112-1--1-111-11--11-1---11112121-1112121112121E111-13318112-111--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.93 Epsilon subunit of F1F0-ATP synthase N-terminal domain
[ 503] -------------------------------------------------------------------- 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 22--111-411-1111111111111111111-1111111111111111111111-1111111111111-1111111111111111111111111111112121112-2511112111211111-11111161-111-11-111211111-11-11111211111111111111212222I2112243441322221112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.188 Prokaryotic ribosomal protein L17
[ 504] -----------------------------------------------1-------------------- 2452-2--1112---11AA-A2----A799A-22-21-13-1512--21--11111----231-3--223-1-------162---1---------------11----2---------------3-16224-1A1123334-----871153B--222--11-14-8466--------------3154---1-------------------------------1----------222122222222121---1-12-11---1------1-2-------1-------1-1111-11-11---------------11---111124---------------11-------1--14-54BB2571-253331--3---8--1-1--14211242114236-------1--5-2411-141211-21123BBB9B3225--2112-5-----111111111114-144------------5498-5A56-55--------41------2443512-111112-1111-14121321----2212--353172--83----1--1-111911A21-315--4--1--1-1221132F14-----1-1-1211111111-----------1-266--4612-3-2--3-2--1--113-2--41----1238------11-1---2111222211-11211111-11211121121-131582121-1-11--1-1--1211-1111--2111111112----6-22122-1----119233-------12-1-1-3-2--12-331111-223-2----433----------31245544552131112-2--222--------21--21--------5---------------------------1211111111---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1-----------------------1------------------------------------------------------------------------------------------------------------------------------------------------- * d.306 YefM-like
[ 505] 11313111111111113111111121121311-----1-----21213-1223-32242531111-11 22212---------12122-21--21212221111111112111-1--1-----------22222112221--------11112322311111---1---11--22211--------------1111111111212222233321111111111111111111112111111111111111111111--1-1-111111111111111------111111----------1-------------------------------------------------------------------------------------------1---1----------2-------1-1--2--112221----22--211--23-111111111212111112533311111111111-11111111111111112222212222111111222211122222222533-22231121112211111111111111111111111111-111111111111111111122222121131122111111111111231111111111111111111122111-1-2-1-442223-433243418333313-2112211111111111111111242322221---------------------1----11--211111111122222213332322233-3333322333323333333222211122222222222222222233332231-21111111111111111111111112--1-----1----------11111111111-1111111111111-1111111111111--------------11111111111111112-111111------------------------------------121111-11-2511 ------1-----21111111111111111111111111111111111111111111111111111----1--111------11111---12111111111111111-12-2321111111121111121161-221111111111111111111112111321211211-12221111--------1131-4------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.307 Nqo5-like
[ 506] -----------------------15445-524---2--2222212-15-12-2-2-2122-------- 3431------------------------------------2---2---1----1--------2-2-------------------1111-------------------1------------------------------------2----11------------------1--------------------343222223333333333343333333333433333333343------------------------------------------------------------------------------------------66355555555535541553---437--56463445537343333343--3112-11-----1121111114113------------22322222--1-------------1-1-1---1111------------111-621--------------------------------1-1111112221221322222223333132221111--11111222211212111112111-------111-223452554317322216367675562212214-3232-2222122322222225441---44-5224344-4444454344444533444--11112------11111111111111111-1111111111111-11--1---11111111111111111111111--11112-1111111-1111---------1111--412-----------------------2-1211111211211112222---------1555455555554551111111112------B56655542222222233--------------------------4-44444344-4-- --------------------------------------------------------------------------------------------------------------------------------------------------------------2---------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.252 CheC-like
[ 507] -----------------------311111111-----------1--11-11---------------11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3-33883-733-3643332232333233333132432222323133233333332333331312222212222222222222222211143435351445-435851624CCFABBAABA7978IDBF9i*D-DBC7959E7AB87B957A76G9DF99677C766485A444B713312---33DDJL2J7--5564- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1- * g.80 AN1-like Zinc finger
[ 508] -------------------------------------------------------------------- 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--11111111-111-11-1111111111111111111111111111-11-1111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 22--112-411-111111--11111--1111111111111-111111-11111111111111111111-11111-11-1111111111111111111111222112-11121111-1111-11122-21372-112111121111111--111211211--11111-131--1312232G222221244121111111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.155 L21p-like
[ 509] -------------------------------------------------------------------- 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111-1111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111-11111111111111111111111111111111-11111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111-111-11111111111111111111111111111 11----1-1---1111111111111111111111111111111111-111111111111111111111-11111111-11111111111-1111111111112112-1-111212-1-1--11111-11371-121----1111111---111111--1-11-2111111211233222M1222243281231111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.27 Ribosomal protein S16
[ 510] -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111-1111111111-1111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111-111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 1---111-1---111-111111111111111-11111111-111111-11111111111111111111-11111111-1111111111112111111111111112-13-212111--1---1111121271-21211111112--111-1--111-1111-11121111121112221I212118313151--11213 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.108 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
[ 511] 11111111111111111111111111111111111111111111111111111111111111111-11 1111111111111-11111-1111111111111111111111111111111-111111--1111111111111111111-111111111111-111---1--111111---------------111111111111111111111111111111111--111111111111111111111111111111111-----------------1--------111-111------------------------------1----1-----11-----111-----------------------------------------------1--111111111111111111111111111111111111111111111-11111111-----111111111111111111111111-11111111111-11111111111111111111---1-11111111111111111111111111----------------------11111-11111111111111111111111111111111--1111111111111111111-111-------111111-11111111111111111111111111111111111111111111111111111111--1-1111111-111111--111111111111---1111------11111111111111111-111111111111111111111111---11-1111111111111111-1111--111111111111---111111122211112-----1---------11111-1111111111--1-1----11111111111111---11111111-1111111111111111--11111111--------1---------------------------11111111111111 12--111-31112222122222222222222222222222222221222222222222222222222222222222212222222222212111111111221331-1314563233343233135132AP3-449142334245143-2321432223-1123221222411212111811-1111212111121121 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.104 YjeF N-terminal domain-like
[ 512] 1112111111111111111111111111111111111111111111111132212222222---1--- 11112111222-1-11111-12--121111113121-132-4131---211-1111------1-11-221-----111---11-----11111111---11111-1---------------------------1-11122---2-1111111--11111111131111111111111111111------1-211111111111111111111111111111111111111-11111111111111111111111-1111-111----111-----11111111111221111111111111111111111111111111111---1111111112122-11111211111111--11-----1---------1-11111-----21-221-------------------34333545121-11111222121111-----3------1-------------121--------------------------------1--111-13222232222233222222222222232--2221111111112112311-11111111111-1111-11111112321111-1----1-----------111-111----------------11121111-111121222213222222223231---1111------11221111111111111-111111111111111111111122112111111111111111111111111--222222222221---1---------11312111111-1111111111111-11111111111111111111111---------12112111112211111111111111111--21------11111111--1-------------------------1--11--------- 1111221-733222211211111111111111122321111-11111122111111111111111111-12-11122222211112111121111111111111111131422221-111111111111231-1111111111111111-11111--121111433142253532312291111254191341211111 -------------------1---------------111------------------------------------------------------------------------------------------------------------------------------------111-- * d.63 CYTH-like phosphatases
[ 513] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------1-------------------------------------------2--1------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------111111111111-1---111---11--------------11----11-------11-------------------------------1--11----------1-----------111111111111--------1------------------------------------------------------------------------------------------------------------------------1-1---1------------------------------------------------1-21-1---------1-----1-1-11---------------------------------------------------------------------------------------------------------2221--1--------------------------------------------------------111-1111111111----------------1-------------------------------------------1-111-1--1---- 3433336-623233333333333333343332333323333332233333323223333333333333333333333233333333333343332333333423352343O6C966B6775695B98D7NhB-B9G67569689557876976A7669899E3FAD8B89FACAA3663E2323365953333323327 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.278 Ligand-binding domain in the NO signalling and Golgi transport
[ 514] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4322554-A33-336223333333333324333333332232233333333333233333332221122-2-2222222222222222223323353333233351-552BBD78B968858A7BB7R9R*E3DAM7A56B79C67AA57E45JABA5834L88666766I59731674A44457C77C3S91453541 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.217 Surp module (SWAP domain)
[ 515] ---1-11111111111-1111111111111111111111111111111111111-1-----1111-11 1111111111111111111-11111111111111111111111111111111111111--121121121211111111--11111111111111---11-1-1111111---------------11111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111----11-1---111111-1-111111111----111-11--1------------------111111111111-1111111111111111111-1111-1111111111-11111111--1111111111--1111111111111111111111111-1121111111112112121222111111111111111111111111111111111---11111---------------------11111111111111111111111111222221111111111111111111111111111111111111111111111-111111111111111111111111111112111111111111-1-------1111111111111111111111111111111111111-1-111111111111111111111111111-111111111111111111111111221111111111111111111111111--111111111111---1-----111111111111111111111111111111111111111111111111111111--------111111111111122111111111111111111111111-------------------------------------11--111111111 ------1-321-11111111111121111111111111111111212121322211111111-11111-1111111111111111111111111121111121112-12-21212111111111211B1AN2-542-1-121111-1-1-11-2121-21321211-1112--11111181111111221121111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.210 Argininosuccinate synthetase, C-terminal domain
[ 516] -------11111111--------1--------11111111111111111111121111111------- 1231112222121222222-23222422222233332222121221111111222112--111234222211111111--31211111---------------2--111---------------11111111111333331112111111111122111111111122111111111111113222211--21111111111111111111111111221421111111141-11111111111111-11-1------11---11-------111111-------111------------------------1--111-----3-21-------2-2122221111-11-322112211121211113---1311222211111222222222222233343343335-2222222336212443222222333232122211112231111111111121121---11111---------------------11111222222333333124433332444414322222311222113222122531111111111111111111111-21111111111111111111111333323121-111-------1-------1211111----111--------------------------1111--------11------------------------------------1122-----------------2----------------------------------11121---------------111111111111334322231221111111--------1----------1-----------------1113111111-------------------------------------12--12111111- ----11--21----1-1252221212122222212111111111113346432333211111211111111111111-1111111111112111111111111111-113------------------------------------------------------------1----11128111212133211111111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.154 DmpA/ArgJ-like
[ 517] ----------------1-----------1-1------------------------------------- ----111-----1------------1-------------------1--1111111--1-----1111111--------3---1----------------------------------------------------11122-------1--------------------1---------------1----1---1111111211111113122-21111-1-2118688891--1111111111111111111I3-15E1131555--5635622322243454453335443453554434334233333434441114444-1-3O1111121614-C111442-1-3-4--1-----------655-1231--1111-1111112211111111111111111111-11111111121-111112222111111111111111111--------21111111------------------------------1111111111111111111111111111111111111111111111111111111111111111111111111111-111-112122222-11111111111111111-------------------------1131----------------------------1-11-11------611133-3555375764-4334655654465443444867132226754566875638345444255232-322222222222111---------------3333131----2111----------------------------------------113--------1211111111111111---3-------------------------1-1------11-------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.54 PTS system fructose IIA component-like
[ 518] 111-1------------2------3222D413----G5-----11-11-1---3B5A5D35111---- ---142--11-------33-3144-233333-11-13--21-111---------------221-51-31-4----1----1----21-------------1---2-11-------------------------1-1111----3-13442222222------3417343C-------------11451-----------------1----------1---------------------------------------------------------------------------------------------------------2------------1-----------G---------11---------2--1-111-----------2----------1-11111111-13543331----2---1-211-1--1---9921111-EFNNNNNNNN71187-2---------------------------------------------1-----------------1------1-----1--1----3-------1-6931554------12----------------------1---61--------------------------1--1----------------1--------1------122-------------------------------------------------21-----------------1---111-----------------1-11111----1-1-----------------1-1--------------1-1------1------------------------------------------------56-------------------------------------------------- --11116----1513--21121-----2222121111------1122-11113122----1---1-----13--1121112---111---------111-----2--3K1A4545733331232331333C3-434-33231343133213233342322231291121166B7-G1------1-1-1-1-P------2 ---------1------------------------------1-----------------------------------------------------1-------1----------------------------------------------------------------1----2-- * b.86 Hedgehog/intein (Hint) domain
[ 519] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------1----222222222222222-----------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----2-----11-----------------------11112111-----------------------------------------------------------------------------1----11111---------------------------------1122222222111--------------------1---------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- 2322312-3---3434333222212222222222222222122122221222222222222223232213533435525533332211233233242332221637141269B67986686777FD6K6b*F-N8R5574D479667866856E5946834434522343833423332E231339BBT3NA3255553 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1- * a.42 SWIB/MDM2 domain
[ 520] ----1-2-1111111112---------2---------1------2-----111111121--------- 34A4922433323234433-3322243333322222456645743546233153333211225-4495C55-----------1-----11111311---2613333544---------------111211111314557722256--11----------------21-2-------------55544---4243333322222233322222222242321112------6311111111111111111111------------------------------------12211111-11-----------------------1-------1--11-1-311-11---1--51-12---1-2-12122311--3-5----------1111-----12---11-111112-22222222111-122--121-1231-----1--------11111111-111112-------------------------------1-----22-3111-113111121221111---1211-1--11------1----1111---------------1--1-----1---2-----1------1-11-121-1----------2-------------------1-------2----------------12---1----------------1--2122111--1111-1121-11--1--1111--11-----------------1-1----1---11111111111-------------1--11---------------11111-111-2-11113333132431222------------------------2-11-11---------1-11--------------2---------------------------1---2----5-1 11-122--3112121111123345354111111111111111111111221111-11111111111111111111111111111111111111111111133111-111221-1111112-11111-11351-213122111111111211111111-123111111211-1-32-11-411122112213-1211111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.134 LmbE-like
[ 521] --------------------1--1111111111-11111111111212-111121111111------- -12-111111111111111-1111111-11111111111111111112111121211111111111111111111111-1111-----111111111--1111121111111111111111111-------------------211--1-----------------111-------------11211111211222224331322442121111322112121111111112111111111111111111111111111111111111111111-1111111111111111111111111111111113111111111111112121222222212112221111-21121--2211222111211111122111------------11----------------------------------------------------------1---------------------------------------------------111111111111111111111111111111111--11111111111111111-111111111111111111-12111111111111111111111-----1111111111111111111111111111--1111211111211111111111111111111-1-11111111111112111111111111-11111112111111111111111111111111111111111111111111211111111111111--1-111112322122221111111112-1111222222222221222222222222212221----1-1-2111111111111111-------------1111------1111111111-----1-1-1111-111111-11111-2---------111 ----221-21121112132222233112222122321322222122222223332221222211111111111112111111111111113212111111111111112-2132111111211132141D91-31221-121111112111-111121111-111111111--21------------1-2--------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.135 NIF3 (NGG1p interacting factor 3)-like
[ 522] 1111-111111111111111111111111111111111111111111111111111-11111111-11 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111---------------1---1---------------1---------------------12112211111------11111111------------1111111-111111111-11111111111111111111111111111111-111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111-11111111111111111-11111111111111111111111111111111111112-111111111111111111-1111111111111111111111111111111-111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111-11111------11111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-------111-1---1111111---------------------11111111111211 111111-152311111111111111-1111111111-2111111111111111111111111111111-11-11111-111111111111211111111111121211212111121-1-1-1111-11551-31111--11111-111-11-1-22111--11211111111111111611111122212211111-1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-- * a.143 RPB6/omega subunit-like
[ 523] -------------------------------------------------------------------- --------11--------------------------1111---1--------------------211121----------------------------------------------------------------------------------------------------------------11------------------------1-----1-----------------------------------------11------------------------121----------------111-11-----------------------------------------1------------------------------------------------------------43442225-1--------1--------1-1------1-1--------------------------------------------------------------------------------------------------------------------------1--------------------1------------------------------------------11--------------------------1---------------------------------------------------------------1-------------------------------------------1----------------------------1------------------------------------------------------------------------------------------------------------------- --------------1-322----3-211111111111111111-----11111122211222------------------------------3--------------2-3ZCD8A9NGF8DHIEYKCGDUyF-FFLBFECLDDKEBEEIDGC7FFDBB858314JBBC8CC59J6-111----2-4314151--1211- -----------------------------------------------------------------------------------------------------------1------------------------------------------------------------------- * a.133 Phospholipase A2, PLA2
[ 524] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1--------------------------1-------------------------------------------------------------------------1--CSTJOUE9DDDBDDiWAO6**H-ZGhB999H7DEC9C8DAG79Q9DACE5BBE9952Q88B2566------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.194 L27 domain
[ 525] 22-2222222222222--222222111111112222222222222122222222-1-111-2--1-11 1111111111111111111-1111121111111111222211121-1111111111111111111111111----1-----11111111111-111---111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111---1111111111111111111111111111111111------1111111111111111111111--1----1---1111----111-111111-------11111111111-----------------------11-11111111111111111111-111--1111111111211111-1-11111122211111112221112222222222222222-11111111121121122222222211111112111122211111111111111111111111111---------------111111111121111111111211111111111111211111111111111112111212211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111222111111222111111111111111111111111111111111111111111111111------------------------------------11-111-1111111 ------1-----111111111111-1-11111111-111111111111111111111111111111111-11-11111111111-111111111111111111112-12------------------------------------------------------1---------1-111-1111-121221111134551 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.16 Lumazine synthase
[ 526] -------------------------------------------------------------------- 1111122222222221222-2222222222223222111111111111111111111111221122121121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112122222112222211211111122122221222222221112222221222222222221111111111121111121121111112221111111211212121211111111111111211111111112111111111111122111111111111121111111111111111111113111111111111112111111211111111111-11112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111112112111111111111111111111111-1111111111111111111111111111111111--1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 ------------------------------------------------------------------------------------------------------------3-------------------------------------------------1----1---------112322O222112112-2411----2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.172 Helical scaffold and wing domains of SecA
[ 527] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2222441-944-11222222222323422232222222222222222221222222322222122422122222222122222222333241223332222223362262478678476477D6GLAOBw*P2REa4A8AE6AmD87756C65A333446986432243644332-431A11112456D2641122221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.305 NAP-like
[ 528] -----------------------11111-111---1--1111123-24-2422-1-1-11-------- 1221-----------12----1----------1-------2---2---1-------------1-1-------------------11--------------1-2-92622-----------------112---21-12222---11113232--------------22241------------4-------111---------------111121---11111--------11------------------------------------------------------------------------------------------41113111111111121221---114--11131114113212111231--3123223-----4125431133114----------1-2252256711--1113424224641-2-1-2-333324---------22211744------------------------------1-312211113335434222266372224143244522--11141422231521122121252-------111223262231521843321787383613776774221111-111111-1-------21-4---32-324111152222221122212311133---2231------11111111111111111-1111111111111111111---111111111111111111111111-11111-111111111111---1---------22512-----------------------1-1344433335434334444-----1---11112233331113333475774441111--723333332222222211--------------------------2-12211111-2-1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------2---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.40 Methylesterase CheB, C-terminal domain
[ 529] -------------------------------------------------------------------- --1----1---------------------------------111-----------------------313------------1-----------------------1--------------------------------------1----------------------2------------------------------1----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------21----1---------------1------------11-----21-------1------1----------------------------------------------------------------------11111-11----------2-----1------------2--------1-3---------------------------1----1----------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1---------------------------1-11111-21-1111-111-------------------------------------------------------------------------------------------------- ----2-1-----DC3ADGFB344A8947777771115433433665A434FH8C78HHC877----------------------------23DK13-----52-----F-Q584645454333343374AI3-85B443462354443433443563359DF1331B8FOA665--11-----1-F52IC-D1-8FCJf ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.86 Di-copper centre-containing domain
[ 530] -------------------------------------------------------------------- 111------------1111-11--1-1111111--------11----1---------1------11---1---------111111111111111--1-11111111111--------------111111111111-----111-11111111111111111111111111111111111111-------1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1--122111111111111--11-11111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111--11111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221111111111111111111-1111--111111111111-111111111111111111111111111-1111111-11111111111111111-11-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111121211111111111111111112111111----------1----1-11111111111111111111111111111---1 11--111-1---111111-11111111111111111111111111111111111-11111111111111111111111111111111111-111111111111112-11-223111211111112114-361-11111-11-111111111-131111111111112211112123222O2222262241321111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.70 ATPD N-terminal domain-like
[ 531] 11-1--1111111111-111111111111111111111111111111111111111-111-1111-11 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111211111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111222222221222222111111222111111111111111111111111111111111111------1---11-------11-1111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111-11111111111111111111111111111111111111-11111111111-1111111111111111111111111111111111111111111-----------------------------1111111111111111111111111111111111111111111111111111111111111111111111111111111311111111111-21211111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111--------1-1---------------------------1--1-1111111 11----1-1---11111111111121111111111111111111111111111111111111111111111111111-1111-11111112111111111111111-13------------------------------------------------------1---------1-1121G1111211121121131111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.258 Chorismate synthase, AroC
[ 532] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----9C7-----66711111111111111111111-11111111111111111111111111111---111111111-11-11111111111111111111-1111-A--DNNJSMSCB98CCCRR9HAE*CBIHJ9BAACCBFD4B97ATA8FCTDC76IK9757A887B6775------------1-1--------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.216 I/LWEQ domain
[ 533] ------------------------112-1--1--211111111-----1121211111111111---- ---21------111----------------------2222--11-----------------1--------11111111111----2------1-11---------21--111111111111111-----------222211113-2----------------------------------------------------------------11-----------------------------------------------1-----11------------------------------------------------------------------------------------11---------2------1--2-----------------------------------1------3---------------------------------------------------1111111---------------------1------------1121111--2111111---1-------11-1------111-3---------------1--1-1--3111-11-1111--1-----------11-11-11----1111111111111111--1-----------111111111111111111-------------1311-112223231421-3231112233242112112223111223211222221223212-13221131--11121111111--1------1111-------------------------------------1---------11----------------------1---11111111----------------------1--11111---1--211---1111-1111-1---1-1--2-- --12322-B64-3324443334332431111113332333233111333333332333311112424313334242324333333323321241212112113222--3152524421325334443428U2-31522534334-133212223242423522311-63242331E525137266MFMM4CB--34333 ---------------------------------------------1-----1----------------------------------------------------------------------------------------------------------------------1--1- * g.54 DnaJ/Hsp40 cysteine-rich domain
[ 534] --------------------------------------------------11---------------- 1111111111111111111-11111111111111111111111111111111111111111111112111111111111111111211111111--1111111111111--------------1221-111211211111111112211111111111111121111111111111111111-----111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111-1--122111111111111--11111112111111111211121111111111111111112-1111111111111111111111111111121121221111111111111121121111111111111111111111111111111111111111111111112122112222221211311111111111111121211112111111111111112211112221121112111111111113311111121111111111111111111111111111111111112121111112111111111111111111111-11111111111111111111-11111111111111111111111111111111111111111111-1111111111111111111111111111112222121211111111111111111111111112111111111111111111111111111111121111121211111111111111111111111211----------1----1-111111111111111111111111111112111 --------------1------2-----111-11111-------111-1------231-----1-111---1-----1----------21----1---11------2-----111111-----1-21-1-15--11-----1--11--------1-1------22--12--C-121211------1-324-12------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.18 F1F0 ATP synthase subunit A
[ 535] -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-1111111111111111111111111111111111111111111111-11111111111-111111111-111--1-111111111111111111111111111111-111111111111111111111111-11111111111111111111-111111111111111111111111-11111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111-111111111111-11111111111111111111 21----1-1---12------------------------------------------------1-11111-11-11-11111111------11-111111--111---121112111111--1121111-352-22411111-11111--111-1121-1121-211-11-1--1-1112-221223223-21--2111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.301 L35p-like
[ 536] -----------------------1-------------------------------------------- 112-2---------11111-11--1111111111111111-1111111-111111-----111-113242----------1-------------------1-1-111-1---------------------------------------------------------------------------------1-111111111-11111111111111----11--------11---------------------------------------------------------------------------------------------------------1-------1----1--1111-111111111--------1--1-----2252341122222----------2---------241--3324644643522------2222------------22-----------------------------------111---11-1111-111----11121111---21221---11---111111-1----1--1-----------111-1--------------111---2--1121-1---------------------------------------------------------------------------------------------------------------------------------------------------------------11111------------------------------------11111-11111111111------------------------1111111----------------------------------------------------------------1-1 ----223-422-2232222222222-22222322222222322222222222222222222222232222222223222222222222223222222322232323-23579987853566455BA5A5Iw8197I743658786375267359486554636553474375A44-23132322221642232232223 -----------------------------------------------------------------------------------------------1------1------------------------------------------------------------------------ * b.131 SPOC domain-like
[ 537] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----423-----11233222422252321222222122121411211322222434221221222222-2562224434332222233323131432222322A8A121269BAGG83224445H7494Mi5-EAH24526354725442932C55434342623238346223312117111-2MgS*2*I--1111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.88 SRF-like
[ 538] -----------------------------11------------------------------------- --1-------------------------------1--------1------------------------1-------------------21----------5---41------------------1-------------11---1-1-------------------1-11-------------------------------------------------------------1---------------------------------------------11-----------------------------------------------1-----------1----------------------------------2-1-----2----11---------------------------6-2-2---337-3-1----1----2122-221----------1-2--1--------------------------------1----12--4E77767D77777558CCCA-BB54117---4192-M--7---A-------2B------------31--------1-22---1-1-22-21----5b---1----1-----3--------------313-51--1-2-----11-----------1----5--------14-6213-333-43532132-3--4214344---2-111153DB5-11221-2222111213---1113--255576524576---------------535----3----------3342223---21BCAAA48355653-62E----------32413333332211--19299A88-------------------------------------------------2-------------- 81------3--------1-----------------------------------------------------------------1--------------------------C-------------12-------4------------------------P----48--------L---1-------1----1---116-- ---2-------------111----1----------111-2--111-----------------------------1-----------------------------------------1---1---1---------11--------------------------------------- * b.108 Triple-stranded beta-helix
[ 539] -------------------------------------------------------------------- 1111111111111111111-1-111111111111111112111-2111222221221211111111212111-112111111-1111111----11-11111-11-1-11111111111111111111111-11111111111-1-1111111111111111-111111111111--12-1-111111111111111111-1111111111111--111--11111-111111111111-111111111111111111111-1111111111-111111-1111111-11---11-11111111111111111--1111111111111111111111111111111-11-1-11111111111111111--11-1111111111111111111111111111111111111111111111-11-1111-1111111111111111-11--------1111111111111111-1111111111111111111111111111111111111111111111111111111-1111-1111111111111--1--211111122222---111--1-11-1111111-1-111--1-111111--1----1111-1--11-111-1--111112211111112111-111-111111-11-111-111111111112121222111222-22-222222--1-2--22111-111221111-2211211112222211-111112122-22111112211111-1--111-111112221112-11-2111111111111111222111-111-11111--111-11-11111122222211-11111111-111111111-1-12-11111111111111111--11--11-111--111111111-1111-11111 ----11------11-1-1-----11-1--11-111--11111----1111111111111111-11111-11--1111111-11111111-11--11111111--1--1--21-111--1---1-11-11141-112-1--11--1-11--11-111-111--1111-112--1-121114111111212122--11111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.42 Ribosomal protein L36
[ 540] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111775-844222111111111111111111111111111111111111111111111111111111-11111111-1111111111111111-11111-11232-656CBDCF9B9B8B98AEF8HBZ*94E8H8B97CA9F78888CCB6JB988935F56A7596763596-324M3233482281664578A85 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.169 BEACH domain
[ 541] 111--1111111111111------------1-----------------------1111111-11--11 1121111111111122111-11111111111111111111-11211---111111111--113-1111111----------11-----111211111--111121--211111111111111111111111111111111---2--11-111------------------------------11111--1-111111211111111111111111111111111------1-11111111111111111111-1--11--1-111--11-1--------------111---------------------------------11-1------------1-11----1-1---111111--1--1-21-11-111-----1------111111111111-111--1-1-1-11111111111111111111111111-111111111111--------111--111------------------------------1131-111-111111111111111111111111111111111111111111-1---2----------------111-1111----11----212121211111113-111111111111---------1-111--1121111111111111111111111111111---11-------11111111111111111-11111111111111111112221111111111111111111112111111111111111111111--1111111-----11111111111111111111111111---1-111111111-1111111111111111-11111111111111----------------11111111---------1--------------------------11-11-----1111 11--331-732111111121111111111111111111111111111111111-11111111111111-11111111111111111---12111211111111332-22325222232123232222423G3-243322222224223412312221231184322441363841115-----3153421211147561 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.109 PEP carboxykinase N-terminal domain
[ 542] -----------------------11-11-111---1--1111123-11-2422-1-1-11-------- 1221-----------11----1---1--------------2---2---1-------------1-1---------------1----1--------------1-2-52323-----------------111---21--1122-----111111--------------32221------------2-------211222222221222222111121222111111111111112------------------------------------------------------------------------------------------31123111111111111111---115--11131114213212111221--2124334-----3135631144225----------1-2242244621--1113323223531-211-2-444425---------22211734--------------------------------211211-11112213111133241112121142311--1113142222-421113121242-------11-2232722215318433217975748247757552-1111-1111-1-1-------21-5---32-224111142222221122212311133---2241------11111111111111111-1111111111111111111---111111111111111111111111-1111--111111111111---1---------12312-------------------------1433334324434334444-----1---1111233333111332244444333------421122222222222211--------------------------1-11111111-2-1 --------------------------------------------------------------------------------------------------------------------------------------------------------------1----1------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.58 Chemotaxis receptor methyltransferase CheR, N-terminal domain
[ 543] -------------------------------------------------------------------- 111-311111111131122-22224222222223334223-211-2--------------5311F7A1121-------11111-1111--------1---1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111---1111111111111111111111111111111111111111111111111111111111111111111111111111111111232121211111-111111221111111111111111111111111-1111-11111111111111111111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111-1112111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111--11222221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111222222111111111-111-1---1-11111111-111111111111-1111111- --------221--------------------------------------------------------------------------------------------1-1--32-----------------------------------------------------1-----------111-----113111-21121---1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.222 YbaB-like
[ 544] ----------------------------1-1------------------------------------- ---2322111112121111-11--1422122-133313221---32312221434112--11223452431-------11212----------1----------1------------------------------2223311121--1--------------------1-------------1111111--112222223323222223211112322111222444445121222222222222223222322112311111221122122111313222211211111111211111121121112112122211122221211222222223321122222122-221111111-1-1211-3221121--------------11---------2222-222-24-11111-1113--311-233552331----1------2----------1111---2----------------------------------------111111121111121222211111---------2----1-2--1----211----------11----------2-12222--------------11-----------------------------11-----------------------------------------22--11-1111121211--111211111-111111112221---2----------------1111111---111111111111---------11111--2-1112-1--------1----------1---------------111-------------1------1--------------------1--------------1-211111-1121121---1221111111111111111---- ----11--21----133221111111211111111112111111112136224433222222314112-1111132212211111111211231213232111111-1-14112112111111111111281-113111-1-1111111111-1111111--11211--2331---11181111121232211111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.208 DhaL-like
[ 545] ----------------1------2---11-111111111111111111111111-------------- ----111111111111122-21112122221111111111----11111--1121111----11---1---11111111---------111111111--1111111111---------------1---------------111---111111------------------------------1-1------12111111111111111111112111111111111111111111111111111111112111111111111111111211112111111111111111111111111111111111111111111111111---1111111112111---------1--1-1----1------------11--1211111111111111111111311111111111-111111111111111111111111-1111---111111--------------11-------------------------------111111111111111121111111122221211211111111112111111211111121111111111111111111-1------------------------1------------------------------1111111111111111111111111111111-1111111-11111111111111111111-11111111111111111111111111111111111211211112111111111111111111111--1111111111111111111111111111111111112111111111111111113111111111111111111111111111111111111111111111-1----------------111111------11---1-1111-------------1111 1111--1-311-11211111111111-11112111112111111111111111111111111111111111111111-111111111111211111111111111131611212-1511-111111331381-31411216113-1111112-21121223111121111-11211121M1111112-51312111111 ---4---------------1-1-------------211-2--------------------------------------------------------------------------1---------------------------------------------1---1-----1-1-- * d.117 Thymidylate synthase/dCMP hydroxymethylase
[ 546] -------------------------------------------------------------------- ---------------------1---3------1111------------------------------------------------------------------------1----------------------------------------------------------------------------------11111111111111111111111111111111122222211-11111111111111111111-1----------11--1------------------------------------------1---------------------1-1--11-111--------------------1-------------------1--------------------------------1------------------------------------------1----------1-1111111111111111111------11111111111111111111111111111111111111211111111111111111111111111---111-1----------------------111111---------------------------11112---1-1111111111111111111111------111111153332313346354254-43344453354453333345782322244445444454544443454332531323223233432--11---------2----11111111111111111111111111-11111111111111111----------11111111111111--------------111--------------------------------------------------------- 1---112-1-112321222222222222222222222211222222222222221221122221222222232222222222222222212222221222222434-221445213221133234314-3A31343131332333232233234122221212222132313331111111111-11112111-11111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.23 Open three-helical up-and-down bundle
[ 547] -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111-11111111111111111111 ----11------111----------------------------------------------------------------------------------------111--2----------------------------------------------------------------1--12272212-4254-221-1111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.99 Ribosomal protein L9 C-domain
[ 548] --11--1111111111-111111111111111111111------1-1--1111111-11-1111--11 111111-111111111111-111111111111111111111111111111111111111111111111111-----------1-111111111111---1111121111---------------11111111111111--2221111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111-11111111-11111-1-111111111111111--------------------------------------------11-----------------------------11--111-1-1111111--111111111111111111111111111111111111-1111111111111111111-11111111111111111111111111111111111-----------------------------11111111111111111111111111111111111111111111111-11111111111211111111111111111-1121-111111-212222122121111112111111111111-1-------11111111111111111111111111111111111111--1111------11111111111111111-1111111111111-111111111111111111111111111111111111111111111111111--1111111----11111111111-1111111111111111111111111111111111111-1111111111111111111111111111111111111111-111111------------------------------------1-1111111111-- ----111-----1111111111111111111111111111-11111-1111111-1111111111111-11111111-1111111111112111111111111111-13-21-1111111111121111141112111-11111-1111111-11--111--121--3111111111118111111-121111111211 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.284 PurS-like
[ 549] ----113-------11----1-------------------------------------------1-1- ----3----------------------------------------1--1--1-2---111-11-111-312---------------------1---1---------1------------------------------------1-2-21225--22-------1---1-1--------------212----1-------------1-----------121--------------------------------------------------1----122-----5---------------232251231332----------1-----1-----------------111-1--1------1---11-----1-1------31232671111111111323233333235-9889963542-26446774667445411--------1----------------1-----------------1-----------1-----212213---1--11111----1111-1--11111--111---11-1-1-1-1-------1-11111---11---1--------1--------------------------------1--------1---------1-------------------------------1--------1-----11-----1--11--1-----1--------------11------------------------1---------------------------1------1--1-21--11111111---1--------------1--------------------------2--11-1111---------2E111111324234322-------------1------1--1----------------- 24--943-C511--1-1-11---1-2--------------------211-12-21111211121-1--221-1------1---113---1-113-2-----212-1-32249E86872532374666619M5-B6B162-94756146234515441-G-11324-31-2H663---314-1-118223165213323- -----------------------------------------------------------------------------------------------------------1--1------------------1--------------------------------------------- * h.5 Apolipoprotein A-I
[ 550] -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111311111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111117111111111111111111111111111111111111311111111111-11111111111111111111111-111111111111111111111111111111111111122111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111222222111111111111111111111111111111111111111111111111111111111111-11111------11111111111111111-11-11111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111--11111111111111-1111--111-111111111111111111111111111111111 ----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-31-1---336-3----111- ----------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------- * d.48 Anti-LPS factor/recA domain
[ 551] --------------------------------------------------1--1-------------- 111212133334341--11-1-----11111-----112252261341312312212-4442-1262653732221--14333-----222222222--1222222212---------------53232222222-22-----3----------------------------------------111112443777776775777667454454777555343433323336233333223333333333324334334333322333342232222222223332222222222222222222222222222333333332544462422242425313369A91423552-4322345344434445-24-1-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------12-1111111111111111211111111111---------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------22222222112222121--------------------------1121-23221---1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.11 Penicillin-binding protein 2x (pbp-2x), c-terminal domain
[ 552] 11----1122222221--1121123113-112------------------------------------ ---11-11111--1-1122-21---122222-11111--11----11-1-----1-----21121-1-3----------2HI1-1111------------------------------------111--11112-11111---------------------------------------------1------1111111-111111111-11-11111-2------------111-111111111111111--------1---11-1--------------------------------------------------------22-------------------------2----JG-----112--------1-1--1------11--211-4---11111111111-112112121-------------1-1--111-11-11211--------1----1-1------------------------------------11131----13111111-1222212-1-2233-12321212212231-21-1---11----------512--213211--1--3----31-1--1111----14321112211-1-------231211121-11-1----22332-48255134452A4----51-------43334415555555555-555555555555555555444422212766666776677766744443324--133333333333---1----------112-333322122221223-------1-2--1111---------1-------------2333222223322211-------------1---------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.184 TorD-like
[ 553] ---------------------------------1---------------------------------- -11-111111111111111-11--1111111111111-111---111-1------11---111111111112111111-11111-11111111111---1111111111--------------111-11----111111111111111111-----------1-----11------------1111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111---------------------------------------------------------------1111111111--------------------------------------------------------1111111111111111111111111111--111-111111111-111----111111111---11111111111111111111111111111111111----------------------11---1-1111111111111111111111111111--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1-----111111111111111111111111111111111111111111111111111111111111111111111111111111111111111------1-----------------1-------------------------11111111111111 1111111-52211111111111111-111111111112111111111111111111111111111111-1111111111112221111111111111111111111-11-4232P222232122342322G2-222232221232131222222222221112221-111-11241111711111111111111211-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.110 DTD-like
[ 554] -------------------------------------------------------------------- 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111-111111 ------------------------------------------------------------------------------------------------------------2-----------------------------------------------------------------11----------------2111--1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.111 Small protein B (SmpB)
[ 555] ---------------------------------------------------1---------------- 1111111122111111111-111111111111111111111---11111111111111111111111111111111112122121111111111111--11111111111111111111111111111121111311111---1111111111111111111111311111111111111111111111111122222222222222211111122221111111111112111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111-----11111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111211111213111111111111111111111111111111111111111111111111111111111111111111111111-1112111-1111-111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111--------------------------11111111111211 --------------------11-1-11-----------------------------------------------------------------------------------------------------------------------------------2--------------1----1------1-----1------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.146 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
[ 556] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------2----1-1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111---1-2-2--1-------------------------------------------1244522-12---------------------------------------------------11111C688C85999699EGFEDD6C9IA3974-185533221C61111--1----23-------11-721----2------------------------------------------------------6822---22--22224222222222222222-1-12----222424644A4557447454-54445664455444444444468243445446664564644442464444442222242222422-22----------11--2222222-221222221121111-1------------------------------2222222222222222434343332222------------------------------------------------------------ --------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------1-----1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.155 H-NS histone-like proteins
[ 557] --------------------------------------------------2----------------- ------1---------------------------------------------------------------------------------------------------2-------------------------------------------------------------------------------------------------------------1-------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111------1---------------------------------------------------------------------------------------------------------------------------------------------------21--------------11------1------------223--------1--------------1-----------------------------------------------------------22-1---1----------------------------------------------------------------------------------------------------------- ----EL----------1--------------------------------1-2-2--------------------------------------1-----------------ABEKCE6AC8BEDAPPEKBt*P1QEV78B9GDFPH4D857GA9G9E8BD442AD821212211D3----------------4------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.1 Toxins' membrane translocation domains
[ 558] 22222232222222222222222244434333111111111112222242343133333331112133 ------------------------------------------------------------------1----------------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1------1----------------------1----11-----------------1--1-1------------1----------------------------------------------------------------11-1---------------------------------------------------------------------------------------------1------1----------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5433322192313333344444343444434344444434444444643344344433343343333333443333323333233334435333333333233244249334633633123242752418U4-4441222523313322233243634324533252634745223332d2322383973562444441 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.31 Cdc48 domain 2-like
[ 559] -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.202 Transcription factor NusA, N-terminal domain
[ 560] ------------------------1111111-------------------121--------------- -----1-1111------------------------------1-1------------1---------1211-1----------------------------11--1---------------------------------------------------------------------------------------1---------------1---11--------21----------------------------1-11111-111111111111121---1111---11111111111111-------------111---111------1111111-1---------1--1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------1-----21--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--131-31--334232-13444133-----------------------1111----2-1-1----------------------------13--1-112-1-1221-C298EACFC7666685G9896EZ91B6C46546667546766654E755773632545279553636-641A11152GRaj1ZF23A8A93 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.23 Tubby C-terminal domain-like
[ 561] ---1--1111111111-1111111111111111111111111111111111111-1-111-1----11 1111111111111111111-11111111111111111111111111111111111111--111111111111111111--11111111111111------111111111---------------111111111111111111111221111111111111111111211211111111111111111111111-11-11111111111111111111111111111111111-11111111111111111-1----11-1---11--11----1-111-------111------------------------1----1----11-1111--1-1-1111111---1-1--1111111111111111111--11111111-----111111111111111111111111111111111111-1111111111111111111211111111111111111111111-----------------------------11111111111111111111111111111111111111111111111111111111131111111111111111111-1111111111111-111111121----111111111111111-1-------11111111112111111111111111111111111111--111111111121111111111111111-1111111111111111111112111111111111111111111111111111-11111111111111-1-----111111211111111-11-----1111111111111111112122211111111--------111111111111111111111111111111111111111--------------------------------------1--1-1111111 ------1-----11111111111121111111111111111111111111111111111111111111-111111111111-111111111111111111111111-14------------------------------------------------------------------111181111111211111111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.168 HisI-like
[ 562] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5511222-A33-1433342334344-34434344431434444334344444444444444454555545555455555555554544444533444344413888-481A5876646265766D95649I7-677456855775557435228552461-266663955C66454423C4414569773443415212 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.83 Tim10-like
[ 563] -------------------------------------------------------------------- 111111111111111-111-1111111111111111111111111111111111111111111111111111-11111111-1--111111111111--1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111112221111111111111111111-222222221111111111112111111111111122111111111111111111111111111----1111111111111-----111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--11111-111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-------------------------111111111111-1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------1---6-----1113-1-1-1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.315 TRCF domain-like
[ 564] 11---1----------21222221111121211111111111111111111111---11111--1--- ---------------------1---1---------------1-1-1---------1--------1-----------------11-11111111111---111112121211111111211111111111111111222--1111-22222212211111111221122231111111111111112311-1---------------------------------------1--------------------------------------------------------------------------------------------1--11111111111--11-----1---1--111111111111111-1--1121111-----111111111111111111111111-111111111111111111111111111111111111111---------1---1211111111111---------------1111-1-111111112222221111122221111112113132-1111111111111111111111111111111111111-1-1-111111112111111111111111111111111111111111111111111111111-1-111111111111111111111111--11111------11--1111111111111-1111111111111111111111--21111111111111111111111111111111111111111---11111111111-111111111111111111222221111-1-11111112111111111---------11121111111111111111111111111111-111111---------11-------------------------1111111111-1-1 -----------1---21223332342322-11122211111212222222333333222111433111121131411-11133345---4821111211113211----------------------------------------------------------------------11214---122237331--1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.106 SurE-like
[ 565] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3-----8-C58844611-1---------------------------1---------------1--111-1----------111--1------1-1----11-1143-164NCDC7G987589B6QD5J9qzL-GEJ7A65H8CF85B561973I9A5E978ABFG22G44634E9-232F111111-1-1-1--68783 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.31 Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
[ 566] -------------------------11---1------------------------------------- -33-41-1111--111111-11--131111111444112213115111-22-2222----122-2-3313--1-----11112--------------------1--------------------111111111--111-----211--1----------------21-31------------22411-----2222222221222222113312222-2111--11111133111111111111111111111---------------------------------------------------------------------12212111111111111---1111--11--11111-222-11121-1---1112111------23211221122111111111112-33233232-22-111211-221--221112233333335--------1---113------------------------------1112--1111-111111-1221--131111111--32231211112-11-1-----1-----11----------21211-12--111-111-212221211--1-211-21-1-1111-1---------21--1--11-1-12-1--1222232122222222222-----11------21--11-1111111111-1111111111111111111211--11112-111111111111111111111--1------------------------111-1---111-1211-11---------11-14344111-111112111---------12--1------1111--22222122-------1-------------------------------------------12---1----2-- ------1---1-1--11212221323132121112122222221121112323312233221------------------------------1---------------A-511--131212--2-211339--11-231141-1-214112-121-1-1--1-1-1231--42------511-11-12-3--3---131 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.58 PK beta-barrel domain-like
[ 567] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------255556e-6248H4**8P3**e-TGM-A46ZBBJE6C836a9-8ABB4A31--8----------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.288 GTF2I-like repeat
[ 568] 432344-122222222435555542121-113213552222221211323332745455541113223 ---------------11-------------------1----------------------------1----1-------11111--------1---------------1-----------------------------------11-1--------------------------------------22---11111111111111111111111111111111--111111111111111111111111111111111111111111111111---1-11111111111111111111111111111111111111111111111111---------11111-1111-111-11--------11-11111--1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------1---11-------1-1-----------------------1--111-1111-111111111111111111111----1--------1111111111111-111-1111111111111111111111111111111111111111111111111111-11111111111111--11111------11111111111-111111----------1111111111111111111---------111111111111111--------------------------------111111-1-111-111---11111111111-111-111---- ----221-21---1111--111111-111--1111111-1111111--111111111-1111111111111111111-11111111111--111111111--1123--614443336223333146251AF3-3343212623223433143352333312132211111421121-1142121121221111-22221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.308 THUMP domain
[ 569] --1-------------1--------------------------------------------------- 1231211111111111111-111113111111122211111111333112213231111111122332311-------1111-1111111111111---11112111-2---------------11111111121111--1121-1-----------------1-1--1------------------111-111111111111111112111111111111-1344454411122222222222222322212---22--3-1----22-------313253333433333333333335555555555555233---533411154111111111122111311311312211111111-211121111141121--------------------111111111111---1-----11--1---11222122--1-1-------111--------1--1-1131111111111111111-111111111111112121------------1111----1111--------------1----1-1--1----------------------1-111111111111111112111111211-121111111111111111111111111----3--1----1--------------------------------212121-1--21111-1--211111111-1111111222222--1111-1111211-1--1-1-----11-122222222222-------------1--22---3-2-------11----------11----------------1-------------1------1-12--11111111------11111111--------1-1----1-111111111111111111111111111112111 --------2111--111111-11111211----1111111111111--111-11111111111-2---------1-----------------1-1-1111--1-----21-------------------------------------------------------------------------1-11-1111------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.121 Ribose/Galactose isomerase RpiB/AlsB
[ 570] --------------1------------1--1------------11111-------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 22116621E76522144444444444444443433343333333334444445434344555222111121122211111122221222454446644444524552286DAC89A46454554E8484Pa6-77C36455557535435443854446353343D1E34B4755111291111153444553456443 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.86 eIF4e-like
[ 571] -------------------------------------------------------------------- 1111111111121211111-11111111111111111111111111111111111111111111111111111111111111111111111111111--111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--11111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111--11111------11111111111111111-1111111111111-11111111111111111111111111111111111111-111111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--11111111---1-111111---11-111111-111111-11111----------1111 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.49 Recombination protein RecR
[ 572] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --22BA3-313---1-----------------------------------------------------------------------------------------1--3H3PNQJCMC6577BC8RD4M9t*K7GFM8B86I8CFB6B987B55R9B8DG3226A74293332543----------1--2--1------7 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.289 WWE domain
[ 573] -------------------------------------------------------------------- --------------------------------------------------------------------------------1-1-----------------------------------------------------------------------------------------------------------12333333443443344323223334422212111111113211111111111111121-211111111211-11221111----11111122222111111111111122222222222212113311112333212222222221442222212251131-1333444234233333-----------1111111111111111111111111111-11111111111-111111111111111111111111111111111111111111111111--------------------11111111-1111121111111111111111111111111111--111111111112111112111111111111111111-------------------------------1-------------------------22111111111111111111111111111111--11111------33223333333323332-33433333333333333323332222233323333333232233133311221222222222222--11111111111111111111-11111-11-11111111111111111111111111111111111111111113222223322211111111111111111-------111-1---1----------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------1-------------------1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.105 Penicillin-binding protein associated domain
[ 574] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-----------------1---------23--1111121111-1---------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --331-4---------1-1----1--1------1-------------113644211------------------------------------1---------------4-*786954323233244253Ug9-934312-2124312113312516533322i*gP7XACCis*-----1-21-1-A55124--12--1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * g.10 Hairpin loop containing domain-like
[ 575] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------9-------1---------------------------------------------------------------------------------------------1-kNRNHO96868BCCKN6J7X*F-KEX8988I8CC66A887O78X8FBBCCNC24HB-513-1182----1--1---------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.64 Somatomedin B domain
[ 576] -----1---111-----1-----1-----11111-11-11111222111-111--------------- --1-3------1-11------1---1------22221112--21231----3111111--22--32CC891-111---1--2111111--12-2------1--22--1---------------------1111--1--12---313114111-111------1--23341------------1-111---1-------2---------------------1------2--13---------------1-1----2-11---1---1121-1-112----------1--11111111111-------------1----------321-1111121-2---------1-1-11--11111---4-1--------1-1-----------------12112----------1--1-11---11-----------1--------1--1-1----------------2-1-----------------------------1-1-----------1-----------------1----------------11--1---1-----1-------112-21-231-241-1-112-2121223321111342--------------------------22--1111----2---------------1-1------1-------111-1-11111111111-111111111111111111-----1---2-222222222222221111---1--1--------------------------3----------------------1-----------221-1111--12---------1---1-----1-1----11211111------11-------------------------------------------11---2------- ----431-211----1-2-211-2-21--11112112222222-----262223---2111--------------------------------1-1-------122-24EK696644454353435352AG4-345241233342232214343355352114962--112--75-77-----61-------2241333 ------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------2---- * a.209 ADP-ribosylglycohydrolase
[ 577] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--891-1--1--1-111111111111111111111111111111-111111111-11111-11111-111111-1-1111111122212212221112-11315-5--CBE9D9D9767897LF6B7R*F5FDE7897A49B868577A97I9B89857E46663333D2364-1----11211236161128DCF3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.324 DUSP-like
[ 578] -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111111111---111111----111111111111111111111111111111-1--1--------111-11111111111111111111111111--------211111111111111111111111111111-11111-11111111111111111111111111111111111111111111------1111111111111111-11111----------------------------------------------------------------------111111111111111111111111-1--1111111111111111111-1111-111111111111111111111111111111111-11111111111-1111111111111111111111111111111111111111111--------11111111111111111----111111222211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1-------11-1111111111111111211111111111111111--11111------11111111111121111-1111111111111111111222112111111111111111111211111111-322222222223---1111111111111111111111111111111111111111112222121211111111111111111111111111111211111111111111111--1111111111111111----------------------------1--11-----1-1- ------------------------------------1111111-------------------------------------------------------------------1121111211111112212231-1111121111112121211111211111--1---------1------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.194 CNF1/YfiH-like putative cysteine hydrolases
[ 579] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----22-5322123224-222222222222122212-22122222222222222222222222222242222222222222222222222222232222-12--212-47FA888J86A5A88CA5B8D*8-B9F5995A99A748927C84QA887A5BE95AB25253485222-2A222---------222222- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.223 Polo-box domain
[ 580] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2111433-511-22322222222222222222222222221222222222222212222222222222122122222222211122222232222222222223241355665655B6543787CB5A4N*A1B7J4446C66A637544844B6856636K53354522625331322e31212A4972942433333 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.105 Subdomain of clathrin and coatomer appendage domain
[ 581] 11111111111111111111111111111111111111111111111111111111111111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 34333332B442333333333333333332333333333333333343333333333333333333332333333333333343333333433333333334335533557363284343433465373DR3-545343443332232443353432332473344433-943333333X3333367983743333433 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.183 Nop domain
[ 582] -------------------------------------------------------------------- 11111---------------------------------11---------------------------111--------1111211111222212221--1111112211---------------22222222222-----11121111111111111111111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111-1-11-----11--111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-----111111111111111111111111-11111111111111112111111111-11111111111111111111111111-1------------1111211-12111-----1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122111111111111111111111111111111111111111111111111111111111111-111111--11111111111111111111-1111111111111111111111111112112122222122221111111111-1111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111-1-------------------------11111111111111 ------------------------1-1------1-----------------------1----------------------------------------------------------------------------------------------------------------2----1------------1---------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.53 QueA-like
[ 583] -------------------------------------------1-11--------------------- --------------12211-1-111111111-11111-1----11-----------------1-1---11--------------------------------1-----------------------------------------11111111111111111111111112111111111111-------122222222222222222222222222222221221111113221111111111111111111-1-2112-121----11-1-----------------11111111111----------------------1223222222222222222212222221-22211222222-1122222111------------11211---1---1------------11111111-------1-2----2221-------------------------11-------------------------------------2111123333221111221311111142211111111111111111111111121121---------1111-----------------------------------------------------------11---1---1-11111---1111-1--1----1----------33115325556556654-554555655556455555433311111554556555543535552323334--422222222222---1----------------------1-1-211------1--111222211111-1111---111-11111-212-2222222-2211----------------11--------------1--------------------------------------- 11------1---------------------------------------------------------------------------------------------------1------------------------------------------------------------------111-----112112-----1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.125 Ornithine decarboxylase C-terminal domain
[ 584] ----------------------------------------1--------------------------- ----1--------------------------------------------------------------1--------------------------------------1---------------------------1----------------2----------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------2-----------------------------1------------------------------------1-------------1-------------------------------------------------------------------------------------------------------------1--------------------------------------------------1-------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------1-1--1------------------------------------------------------------------ --------------112212342727422223311221111111113122235311253222111111111111111-111111111119122-11-------1-1--842B322C43224342A92437C4-436231133333122-232-4312B6---38-9-----4M11-A5-----123TCK2*K--bOlc- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.77 beta-Prism I
[ 585] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --24--1----------------------------------------------------------------------------------------------------5C-4DFFRGK9773CD7JIALCV*D1D7R5797G9AD71C755H33XCK86A4CR56462444F8662-------1-----------1111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.65 Notch domain
[ 586] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------21333-EBADEEGGGGFfCV*D-LDSECFGN9DDADCJ99F6BNCC386---------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.126 Serum albumin-like
[ 587] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2111362221431--1221-4443211121214--22------2------------1-------------------------------------------------------------------------11-------------1----111----1---------------F7--35B8CDAAAA888-979F977C9CA7B888886B991258FA44ABBCCCD98C6AA82425562--678789869888--------------1---------1---1----22211-2--1--3333-214-1221-132-------------------1----21--------1111------------------------------------------------------------ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.167 FimD N-terminal domain-like
[ 588] ------------------------23311111------------2--1-------------------- 21-111111111-111112-1111111111111111123111112122132-222111--111-1121111-1111----111-----1-1---------1--2211----------------1---11---111111-----1-1--1---11--111111---1111-111111111111-----11-------------------1-11-3---111-1--------12---------------------1------111-----------1-----------------------------------------------1-1------------1-------1---1--1--11---1111----1---1-11--2-----13335211115111111111-115-42225521451-122166343423231212112211112111111113311-111------------------------------1312--3-122131121----2221-2-1112432113-151--1---312311--1---21---------213-311-------1-------11-1-1211-1111--------------------------1----1311----2----1-1----1-11--1---111--------1---2-1111111111-111121111-111-11---221-----1---1111--1-1--1-111---11----------------------211---11----------------3223211---2-11212524222333124------------------------21--------------1-11--------------1-----------------------------------1--1 1-----1-1---11111111111111111-1-111111111111111111-11-111-1111-11111-11111111-11111111---2211111---1-111---2412211111211112-211223B2-1122-1-11111-222122131211111-1111-1111--111111-1111111111111111111 ------------------------------------------------------------------------------------------------------------------------------1-----------------------1-1---------------------- * d.303 BB1717-like
[ 589] 2212121222222112222222222----1-2111111111111111111111111121111112-22 111-5---------1-1-----------------------1111----------------21----1111-------------11111----------------2---222222221122222--------------------1-1-1111111111111111111111--111---1-11-22222-----1---------------2211-1----1-----------22----------------------1--------11--111-1--1------------------------------------------------11-------------------------1--12--21211-22-------1121111-------2----112111--11-111112---1--2-12-1--111--211-23----11-21111----------------112111-------1111111111111111111--11--111111112111111122421111112172231--11111-11---1--11-1---111111111111811--22-222242222-3333334331111---222122211122221111222121121111111111-111111111111111111111---1111------22111111221111121-211222122221211111233221111222222222212222211121111112111111111111111-----11111111-111-1-1----1111----------1122221121111111111----------22222222222222----------------2-222222----------------------------------------------1--- ------------------11-1-2322-------------------1--22343----------1----------111111111------------121----------------------------------------------------------------1--------------------1-----------11- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.333 UbiD C-terminal domain-like
[ 590] 111-11-----------------111111211--1---1111121-2222332111111121111--- --2--11----11-----------1------1----------------------------1-------1------1-----11--1----1-------------111-----------------111112131-2---1-111--2--1---1111121212---2--1-111111111111-----1-1--111111111-1111111-1111111---1-1-1111111-133333333333332111221-1-11-1--1111111211121222111----11111111111111-------------11111111111--1---------------1---11--1--1-1--1-3-11-1111-1---2------------222--1---------------1---2--6--21---54------22342-----2--22---11111111-----------------------------------------------2111111-----11-1------111121------21----1-12-11------1----------1--1113-----32----1-112-111--1--212------------------------1--11------1----------------------------------1111-12-111-1111--1--1111111111------11111--1111111111111111111111111--1---------------1--1-----1-------------------------------------------------------------12221211111---------------------------------------------------1-1-------11----------- ------2--------22211--22123----------------1----111222--111111------------------------------2--------------12162211122121111111312A1-2131-112111111111131211122121-52112122113----131111-DPLd1Z6------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.290 AF0104/ALDC/Ptd012-like
[ 591] 221222222222222212222221-----------11111111--112------11111121112--- -1----------------------------------1---------------------------112----------------11222----------------1----------------------------1---------11--1-11111221111111------1111111111111---2222-121222222121222222121111221123-111------221-----------------------------------------------------------------------------------------1211111111111111111-111-11--1--31221211--1111111-1111----------------1--11-----------------------1-------------------1------1-1111111111111--1-----------------------------1----------1111111--------------11--1-1--111-11111---11--1-------------11-1-11111-------------------------111-----------------------1-11----111--111111111111111111111---11111--1111111-111111111111-11111111111111111111111111-1111111111111111111111111-111111111111--11---------1111--------------------------1-2222--1-------111-1111-1111--------------11111111111111--1-112212------------------------------------1111111111---- 11--111-523-112111112211111111111111111111111111111111111111111111111111111-1-1-11111111111111111111111222-141111121111-211-331327H2-21513111-131111-12112111121221311-211211111111A-11-163C71434621111 -----1------------------1------------------------------------------------------------------------------------------------------------------------------------------------------ * d.156 S-adenosylmethionine decarboxylase
[ 592] -------------------------------------------------------------------- -11---------------------------------------------------------------------------672X---------1-------122--451----------------------1---41----------1--2----------------22212------------------------------2--22-----------2------2-----1-3--------------------11-----1-----DD---F-HG4311---1---ACCJJIMJJKIHMG-------------6---------821J*2222222g2d-A3327F7-123--16---------4-----5---------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------2------------------------------------------2----------------12-1-----2-----------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------1-------------------------------------------------------------221144---1--11-----------------------------------------2 -----------------------------------------------1-----------------------------------------------------------------2-1------------------------------------------2---113--------3------------------------- ---------------1---------------------------------------------------------1---------------------------------------------------1-1----------------------------------------------- * b.109 beta-hairpin stack
[ 593] -------------------------------------------------------------------- --------------------------------------1---------------------------------------------------------------------------------------------------------------------------3------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3--------------------------------------------------------------------------------------------------------------------------------2--------------------------------2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 8766----8-----1214322222223222222111232323322211111121-1231222111111-111111111111111111111211111111211------11jEBADCF7686777BA5B3Jg8-G9P8678D688488874868A7C887JD6-11--------------4--19-21133-----2--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.209 LCCL domain
[ 594] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------- ----A94-----122--------------------------------------------------------------------------------------------4242FHDEI78464686VH3L5g*D3QHU3777C78A828645C54H875874985443394252334-21-8---1-4455-511-11111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.14 VHP, Villin headpiece domain
[ 595] 11----1111111211-11111--------211-1--------------------------111---- -11--1-13321-112211-1---13111111-----2121123111--11-211111--224--111--------------5-------------------------------------------------------------1---------------------------------------------1-2111111111111111111122111---11---------1-----------------------------------------1-----------------------------------------1-------------------------------------------2---------------1----------222--112111----------3---4--3-3341-311421-32-121112-1-2--48--4111111112-----11-----------------------------1-1---3GG972222121222211693323-371E214422--1--211312138111--1-1----------1---12--1--------------1-1---------1--2---111-1-1--------------11--1--1211----------------------2111------1-211--1111111111-11-1111111111-1-111-2-2421111111111111111111-------1----------------1111111111-1121----------------------11-1-22221222-111211---------------2----------11--------------------------------------------------------------------1--- ----111------2-222142225557111121111111111111134123424111111111--11-1-11--1111111--------1412111---1141-------2234322111-111111-1241-112122112111111111--112323----11------------118112-----12--------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.44 2-methylcitrate dehydratase PrpD
[ 596] 1111311111111111111111121--111-111111-1111111-122-22212222222---1111 1121-----------1111-11--1111111111111-111111---1------------111-1111111----------112122211-1----------111-111---------------32122312222---11111-12222111--1111122111-1222211211112111111111221-11---------------111111---111-1---------1------------------------1------------------------1----------------------------------------2--11---------12-22-111--2-----12112-22222122221---12---1-----11122--133333------------121111111---111111111111-11-11-1----111---------11----------------------------------1-1--------1111111----11111111-1111------------------1---11222------------1-1-212-222122112-21221222211212242----------------------22111---1111111-1-----1-----1--1-11---2111-------1111-11111111111-111111111111111111111111--11111111111111111111111111----------------111111222221111------------------------1111111-1111----1111---------1----1111111111----------------22------------------------------------------221222222222-- ------1----121111111111111111-111111-1--11111-11111-11111-1111111----1--111------11111111-2-11111111111111-12-2---------------------------------------------------111112112--1--333N242322232112211111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.273 YjbQ-like
[ 597] 11-1-111111111-1-111-111111111111111111111111111-1111---------11--11 111----------------------------------------------------------------------------1111111-2------------1-11111-1---------------1-1-1------12211---1--------------------------------------11-11---11122222212222222211111122211111--------11111111111111111-1111-------------11---------------------------------------------1----------11-------------1111---------1111111111-11111----1-1-1111-----111111121111111111111111-11111111111-12221121112212-1122-----2--1111111121111-11------------------------------11-1111112-----------------------------------------------1111111121111111----1111111111111111111111111111111--------------------11-11--3211-11-11211111111111111111111--1121---11112111111111111111-1111111111111111111222222221111111111111111211111111-22112222222211-1---------111--11-1-1---------11111111111111111111111111111---------111121111111111--111111111111112-111111---------------------------------------11--------- --------------222212222222222212222222121222112122222212222222223222222212222222233322222242222322222-2322---------------------------------------------------------------------------------1-2--------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.37 Siroheme synthase middle domains-like
[ 598] ---1-1-11--11111-11---1-111111-111111111111111121221111111111-----11 11111-111111-111111-11111111111111111111111111111--1111111--111-1111111----111----11111111111111----1---1-111---------------111111111111111111111111111111111111111111111211111111111111-111111111111111111111111111111111111-1111111-11---------------1--------------------------------------------------------------------------11-111111111-1111111111--1---1111111111111----1-1-1111111-----1111111111111----------1-11111111121-111111111111-1111--1-----1111111111111-11111111111111-------------------111111----111111111111111111111111111111111111111111111111111111111111111111111-111111211111111111121111111211--1-------11111111111111111111211111112111111111111111111--1111------1111-111111111111-11111111111111111111111111-11111111111111111111111-11111111111111--1111111111111111---------------11111111111111111111111111111111111111111111111111111----------1111111-111111---------------------------------------111-1111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------111I111112--2-11111211- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.145 NadA-like
[ 599] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------52--221---------------12-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------1-1-------------------------------3----------------------------------------------1------------3---------------------------------------------------------------------------------------------------------------------------------------------1111--------------------------------------------------------------------------------------------------------------- ----22---------13---22-1-1--------------------32-11332--112111------------------------------3--3------------G-sH5D378789366AA789ACs9-96B8BACC84AA36C88563G62277796444--------B6-29--1--12BDHL-6I--3434- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * a.119 Lipoxigenase
[ 600] -------------------------------------------------------------------- --114---------1---------11-----1----11--------------1-2-------------11-------------------------------------------------------------1-------------------------------1------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------111-------------------------------------------------------------------------------1-------------------------------------------------------------------------------244-42---------2222-1------2-----------------------1------------------------------1--1---1-----2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4------1----1-------------------------2----------------------------------------------------------------------- ----5A-----------------2-3-----------111111-----113163-----1-1--------------------------------1------1-----149--381--------------------------------------------------2----------111-----2B*m*-r*------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.78 beta-Prism II
[ 601] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----111-------2--1-----------------------------------------------------------------------------------------232V6434AH8E8985BOKAFBS*B-F9LDAD7B57JA969778A9DB824D8462411521131352-311B---225225-321168771 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.114 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
[ 602] ------------------------1--11---11---------121-2--111--------------- 11111---------11111-11111111111111111111-11111-1111-111--1--111111111111111111-1111-----2222-111---12122213-2---------------2221111112111111---1-121211111111111111111111111111111111111-1----11-111111111111121-1----111---1-11-------11--------------11111--111111---111112---111----------------------------------------------1---11------------11-------11-111-11---------------1-11111-1111121111111111111-11111111-11111111111-1111111111111111111111111--1111111111111111------------------------------1-111111111111111111111111111111112221--1111111111111111111111111111111111111---1----------1-1111-----1-11---111111111111111111111-1111111111-11-111111---11111---1--1-11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1-----111111111---------------22211221111111111111111111111---------1---1111111111111111111111111----111111--------------------------------------1-------1111 ----221------1------------------------------------------------------------------------------------------------222212-1-1-11111-21491-122----1-112-111----1-222211-13111611111111111-222-13-----12-----2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.322 PHP14-like
[ 603] ------------------------------------------------------------------11 11211-11111-1-11111-1111111-1111111111111121----1----11-----111-1111111---------11---11-332211------1-11111-1---------------1111111111111111---1-111111111111111111211111211111111111111111----1-11111111111111111111-1111111---------11-------------------------------------------------------------------------------------------11121111111111-2------111--11-1-33-1--11--111-1-11-11111-----111111111111111111111111111111111121-11111111111111111--1111111-11111111111111-1------------------------------1111-111111111111-111111111111111111111111111111111111111111111-------111111-1121-------------1-----1111121-1-------------------11-11--1111111--111111111211111111111---1111------111111-1111111111-111111111111111111111111--1111111111111111111111111--111111111111---1---------11111----11---------11111-11111111111111111111111---------1111111111111111111111111-----111111111------------------------------------1-11111121-111 ----111-21----1----------------------------------------------------------------------------------------111-13121121--2221211221213B1-12422131211112211221222111--61211------11--111I1112----1---112111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.173 Methionine synthase activation domain-like
[ 604] -------------------------------------------21--11-111--------------- 111-311111111111111-1111111111111111111112121111111111211111--111-1111-1111-111111------1111-111---11122111-1--------------1111111111-11111111-1----1---1111--12111111--1--1-----1----11111--1111111111111111111--111111111111111111111111111111-11111-11111111111111111111121112211111111111111111111111111111111111111111---1111--1-111111111111---111111-11111--11---1----11--1111-1111111111111111111111111111111111-11-11-1115111111111111111111-11111111-11111111111111---------------------------------11111111111111111111111111111111111111111111111111121-111111111----------1111------------1-212111--11211-11--11-1--------------------11111---------1111---1111-1--1--------1------11112111111111111-111111111111111111111111--11111111111111111111----11-111111111111--11-----1111-----11111111111-11111111111111-11111111-11111111--------------11111-----11111111111111---1----------------11111--11--11----1-1--1---2-----------11 ------------436--1-1111---1--------------------1111-1111111111-------------------------------1--------------3------------------------------------------------------1------2-------1----12----1----1315- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.16 Gated mechanosensitive channel
[ 605] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------111111111--------------1-----------111-------1111111111111111111112211111111111111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1111-----111111111111111111111111-1111111111111111111111111111111111111111111111111111-1-111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-------111111------------------------11111----------------------------1111-111111111111111111111111111---1111------11111111111111111-111111111111111111111111111111111111111111111111-1111111111111111--1111111111111111---------------111111111111111111111111111111111111111111111111111111111111111111111-------------------------------------------------------1-- 11--111-31--11111111111111111111112111111211111111111111111111111111111111111-2111111111124111121111111222-12-1121111-21111111111161-111111-11111111-11211-1112111131121212--231222X2123231121213242224 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.248 Coproporphyrinogen III oxidase
[ 606] ---------------------------111-------------------------------------- ---------------11----------------111--------1---------------11---12122------------------------------1---1-2------------------------------------1-1111111-1--------1--1111-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1--------------------------------111111111111---------------11111111-11----------------------------------------22122-111111111-111-1111-1111---------11111111-1111-----1--------------1----------------------------1-----------------------------11--11----11-------------------------------1111-111111111111-1111111111111111111111111111111111111111111111111111-111111111111---------------111111--------1---------------11111111111111111----------11111111111111-----------------------------------------------------------------------1-- ----54------11154333334545422223322322221223323332446512232332-----------2---------------1224111----1-3111-281A2625143333322452337L3-5353332523442222142243245224A2563-237374421221B1112432323321222221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.165 MOSC N-terminal domain-like
[ 607] -------------------------------------------------------------------- ----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------1---------------------------------------------------------------------------------------------------------------1--------1---1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------- 2211322-62222232332333323233333333332333233333222222222221222222333313322123333333333322215334332333342121-15254644684686556E75A4OO4-C595376C5484466534447544332-23532122233642212282223243552432212122 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.135 The spindle assembly checkpoint protein mad2
[ 608] 11----3333333333-2------2112122------------------------------1221-11 1-411-11111----------1--------------1111111--1--1-----1---11---1-11---1-----------211111------------------------------------11111111111--------1-111111111111111111112111111111111111111111----111111111111111111111111111111111------111---------------------------------------------------------------------------------------------------------------------1--1-11---------------11-1111-1--1111111111111111111111111111111111121-111111111111111111111111111222222221111-1111111111111111111111111111111111111122222111111111111111111111111111111111221112111111111-11111111111111111---1-----------222-212--1111-1-11111111111111111111111-112211-111111111111111111111111111---1111------1-------------------------------------------------------------------------------------1-----1111111------------------------1111111111111111111------------11111111111111111111111111111111------------------------------------------------------1-- -3------1------1-1---------1-------1--------1--1------1-1-1---1-111---1-1---1-1--------11----1---11------1------11111-----1-11-1-14--11-----2--21--------1-11------1-112--y-1--2-21K111-1-118-11------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.32 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
[ 609] -----------------------1111111111111111111111121111111------------11 1112211111111122222-22222222222222222222222221111---111111--22212222222--------111211111-----------------------------------------------33333---1211111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1-11-11--1-11111111111111---------1------------1---1----------------------------2----1----------1-----1-------------------------------------------------1--------------------1-------------------1-----------------------------1------11111121111---------11111111---------------------------11----211-11211111111111111111-------------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111-----------------1111111------111---------------------------------------11111111111111----------------1----------------------------2--------------1111111111---- ------1-------111111111111111111111111111111111111111111111111-11111111111111111111111---121111111111-1233---------------------------------------------------------------------11118111111131121-11111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.143 CofD-like
[ 610] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------C9CDDEA8A75898RI6CBg*G1RDQ6A68B7AA87B533A94D696574535872383444522-2526233---------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.217 SAND domain-like
[ 611] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------1HRISJG86B56DAOH7GDc*F-EFO5964E7CEI5B857D65S7FDAF161------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.32 GLA-domain
[ 612] 11-1-11111111111-1121111211211111111111111111111111111-------111--11 1211111111111111111-1111111111111111111111111111-1111111111111211111111--------11111-111-----------121111111----------------1111111111111111---1-1111111111111111111111111111111111111--------11111111111111111111111111111111111111111111111111111111111111-------------11---------------------------------------------1---------11-----------------1---2-----1-2111111--1111--1----11--------------------------------------------------------------------------------------1-1-----------------------------------11111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111122221111111111111111111111111111111111111111111111111111111111111--11111------11111111111111111-1111111111111111111111111111111111111-111111111111111111111111111---111111111111111111111-----11111111111111111111111111111111111111111111111111111111111111111111111111----------------------------------------------11--------1 ------------------------------------------------------------------------------------------------------------2------------------------------------------------------------------1111J111113123-3211----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.151 Glutamyl tRNA-reductase dimerization domain
[ 613] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----223-------2----------------------------------------------------------------------------------------1-22232688AD9D97B7887BI8H7R*B1CBI7876B999679875896CAA78811323342623C378342222211127747-A33132222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.63 E2F-DP heterodimerization region
[ 614] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------11-1-------------------------1-----------------------------------------------------------------------------------1---1---------------------1------------------11---1----------1----------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------2121---84****-*Z------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.142 DNA-binding pseudobarrel domain
[ 615] -------------------------------------------------------------------- ---------------------------------------------------------------------------------1-1-------------------------------------------------------------11111111111111111111111111-11111-11111111111-11111111111111111111111111111121111111111111111111111111111111111111111111111111-11111111221111111111111111111111111111111111111111111111111111111111111111112-12111-2111--1-1-1111-11-1-11111111111111111111111111111-111-11111111111-1111111111111111111111111111111111111111111------------------------------11111111111111111111111111111111111111-11111111111111-1111111111111111---1111-1-1-1--------111111111111111---------------------------11111111111111111111111111111111---1111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1-----11111111111111111111111111111111111111111111111111111---------11111111111111111111111112111----111111--------1-1----1---11---11111--1----1--111-111--1- ----11--211-------------------------------------------------------------------------------------------------31-----------------------------------------------------------------11118112112-----51111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.193 Hsp33 domain
[ 616] --------------------------------1-2------------------1-------------- --43B465113213-----------------------51-341324111211444-111155212449792533333322579----------------------------------------------------44455---54---------------------------------------------111333335642473456563352344221233322222221422222222222221121113111341111211113321124122265555252114111141161132222335443223662215661---1-1111111-1--1--257411-4A212---1-----1-----------------------111------------------1-11111-11--1-----11-111------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-11-11111-1111111111111---------------------------------------------------------------------------------------------------1-----------1------------------------------------------------------------------------------------------------------------------------------------------------ ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.100 Sortase
[ 617] -------------------------------------------------------------------- ---------------------------------------------------------------------------------1-1-------------------------------------------------------------11111111111111111111111111-11111-11111111111-11111111111111111111111111111121111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111112-12111-2111--1-1-1111-11-1-11111111111111111111111111111-111-11111111111-1111111111111111111111111111111111111111111------------------------------11111111111111111111111111111111111111-11111111111111-1111111111111111---1111-1-1-1--------111111111111111---------------------------11111111111111111111111111111111---1111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1-----11111111111111111111111111111111111111111111111111111---------11111111111111111111111111111----111111--------1-1----1---11---11111--1----1--111-111-11- ----11--211-------------------------------------------------------------------------------------------------31-----------------------------------------------------------------11118111111-----11111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.81 HSP33 redox switch-like
[ 618] -------------------------------------------------------------------- -1--4--------------------------------122----11-1----111--1--311-2112111-----------------------------112111--1----------------------------------1---------------------1--11------------111--------1111111111111111-----111--1-111------1---------------------------------------------------------------------------------------------------------------------------------------------1--1111-------211-----------------------------1------------------1-1------11--------------1-------------------------------2--1-111112111221111111111222112111221--112--1-1211-2-----------------------1-----------------------11-121--------------------------------1----11-111111--111111111-2---1----------------------------------------------------2-----------------1------------------------1-----------------------------------------1111-2-1---------------------------------1112121111---------------------------------------------------------------- ----113-----222335333333334222222354322222222245354444444434331111-111--11111111111111---23333591111123213-14144122434424323534412A3-435345342332335343553422222651261111131325122-----2-613252--11---3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.266 Indolic compounds 2,3-dioxygenase-like
[ 619] ------------------------------------------1-------1-1--------------- ------------------------------------------------------------------------------1--1------1121-3----------------------------------------------111--------------------------------------------334------------------------------------------------------------------------------------------------------------------------------------242265555555556454443446252122235445844841433322---2------------------1---1------------------------------------------------------------------1--------------------------------------------------------------------------------------------1---------------4-2--415222--111111152------13-----------------------1-----1---------------111---1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------2---------------------------3223333333-1-- 1111111-3112111111111111111111111111211111111111111111111111111111111111111-1121111111111-111111111111111111222262335312122224293BZ6-6371221422222222123-832322125111115111211112317111311112111121211- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.96 Fe-only hydrogenase
[ 620] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2211562-411-33311111111111111111111111111111111111121111111111232233132222333123333333222-5313232222322334-4D38685446244334266354Ef4-6753423544533433352261444344544462E3764434-34-722244BB7G1E82435431 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.240 BSD domain-like
[ 621] ---------------------------------1------------1--------------------- -----------------------------------------11-----1------------1-----1-1---------------------------------------------------------------------------1121111111111111111111111111111111111-----1-----------------------------------------------------------------------------------------------------------------------------------------------------1------------1---------------------------------------------------------------------------------------------------------------------------------------------------------11121-1111122--1111-11-1--------2--4-------------------------------------------------------------------------------------------------------------------------------------2-3--2-11-----11-11-1---1-11-------1---21421----11-11-1111-11----2211-133333313522---------------------------------------------1111-2-1-2112--31--------------------------------------------------------1----------------------------------------- 1111111-311-11111111111111-111111111-1-111111111111111111-1111111111-1111111111111111111111111111111111111-1A1211111-111-11132131491-21411121111-1111111211--11----11----------2CBG*FGDCDGFJJ1DG34111-1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.107 Mog1p/PsbP-like
[ 622] -------------------------------------------------------------------- ---13112222-1111111-11--1111111111112153-111122111113421-1--112121212211---111---1--------11-122-------1--1-1------------------------1------------------11---------1-------------------------111111313111121221111-111121111121112222111122222222222222222221111--111111111--111--111-111----11111121112121111111111111111111111111--1111111-111111--1111-11111-11-11----11111-111----------------------------------------------------------------------1----------------11---------------------------------------111-11111211111111112222212111--1----------1----------------111111--------------1---------1---11----11---11------------------------111-1-----111111-1111111111111-------------21111212222232322-222232222222222222132411111433432433344444411111111--111111111111---------------11-111111-111--111-1111-11111-1111111111111-111-----1---111111111111212--11111111-------1--------------1--------------------------------------1-- ----11--31---1-11-11-1----1111121---1111111-------1111111-----------------------------------1--------------1-1-----------------------------------------------------1----------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.141 Glycerate kinase I
[ 623] --1--11111111111----------------11111111111111-11111111111111-----11 ----111111111111111-11111111111111111111----111-1---------1111--111---1111111111111-----11111111----11----1----------------------------11111---1--------------------------------------11111111-11111111111111111-111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112221111111111111211111111111111-1112212222-2222111-------11111-------------11111111111---------11-1111111111111-----111111-111-----------------------------------------1-11-------------------------------------------------------------------------------1---1-----------------------1------------1-1111111---------------------------------------1------------------------------------------------------------------------------------------------------1111--------------------------------------------1----111111111------------------------------------------------11----1---1--------1-------1111111111---1 11--111-3111111111--11111-111111111111-1111-11111111111111111-11111111111111111111111111112111111111121121-12-2112211-11111121121382-312111111121111111112111111--1112-11121211111191111123421551-11111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.100 Thiamin pyrophosphokinase, catalytic domain
[ 624] 111-112222222222-2-----4122113121121-11111124233-233311111111222--14 111-132233422322122-221122222222222222231111222122223233121111111221212-------12311-----------112--111111311211111-111111111-1-1-----1143345--111-------------------------------------31111-11211111111111111111111111111111111111111111111111111111111111111-2-11-1---11111111----1111121121111111111111111111111111111111---1111-1-2422211111211-331---1122-1111133111111-1------1113----------1--1------1-------------11111111-1-----1-------------2---------1111111111111--------------------------------------------------------------------------------------------------------------12-111--1-----2121111121111---2----------------------------------------------------------------------1----111111111111-1111111111111111111--------111111111111111111111111---------------1--------------1------------------------------------------------------2--------------11111111111111---1--------------211-------------------------11112222221121 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.76 Iron-dependent repressor protein, dimerization domain
[ 625] ---1-------------------1----------1--------65-5D-1966--1--1---1----- -19-11-1---1---11--------------------213-1-1-----1--1-------1--11---------------2-1-1--------------1------1-------------------2-14--6-----25---118E69KKY--11------381-875----------------35---1----------1-------1---------------------------------------------1--1--11--11-----------1----1--11------------1----111-11-----------32-------1--1----43-1-1-1--2--2-5344387--25---5-1--41-22-121-21--2-1--26285------------21-11241-1-----1-1---2-1-1--2---1-2--1----------111---2------------1-11-1111-11------1-21---21-1---1--------1111---1--12-11-----------1------11-----12-1--11----1--121----5-321-1-211-412--1------11----21-----1-1-5-1----11------1---------------1----1-----A1-3------1-1----111-1---11-11111--1-11-211111--1--1541----------------1--1---1--111111111111---------1-------1-------1---111---11-1----1---212-33------1--------------------------11--------------12--11----------5-----------------------------2--21333--1- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-----1---------- -----------------11-------------------------------------------------------------------------1--------------------------1----------------------------1-------------------------- * d.304 TTHA1013/TTHA0281-like
[ 626] 11111111111111111111111111111111121111111111111111111111111111111111 ----1---------1----------1----------1111---1---1----111--1-----1111141-----------1-----------1--------1--12------------------------------------1--------------------------------------211----1--2----------11-----1111--1------1-------1---------------------------------------------------------------------------------------------21-------1------1------1--1-----------------------------------------------------------------------------1-----1---------------------------------------------------------------1111122211111111111111111111112111111111211211111221----11--1-11----111-------------------1---------1---1-----------------------------1--------------------------------------11--1111111111111-1111111111111111111111-1112111111111111111111111111--111111111111----------------------------------------11-----1--11-------------------------------1--11111111111111-----------------------------------------------------------1 111113115221111111111111111111111111-111-111111111111111111-111111111-12-11111-11111--2221211111111111133511222-11111-123-413B1A2AN5-33A---67--222-11122111-11222113-11511112111111F1112154441311111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.9 Barstar-like
[ 627] ------------------------11111111----------------11221--------------- 11------------------------------------------------------------------1----------11-------111111--1---111111111--------------------------11111---111111111111111111111111111111111111111-------111111111111111111111111111111111111111111111111111111111111111----------------------------------------------------------------------11111111111111111111111111-111111111211111111-1--11-1-------------1---1-11--------------------1-----11--------------111111111111111111111111-111111111-----------------1111---------------------------------------------------------1111111------------1-11111111111111111111111111112111111111111111111111111--122111-11111111111111111111111111---1--1------11--11-1111111111-1111111111111111111111-----111111111111111111111111--111111111111---11111111111-111---------------11111111112111111111111111111111111111111111111111111--------------111-111111----------1111-1-1111111111112111--------------111 --------111111111111111111111111111111111111111111111111111111---------------------------11111111111---112111-2----------------------------------------------------1-------12411121A111224332131------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.105 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
[ 628] -------------------------------------------------------------------- ----1111111-1-11111-111111111111111111111---1---------------11111111111-----------------1111-1------11112111111111111111111111111111111-----------------------------------------------111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------21111-1111111111111111111111111111-11111111111-11111111111111111111111111111111111-1111111------------1111111111111------111111111111111111111111111111111111111111111111111111111111111111111111111-1111-------------------111111---------------------------111111111111111111111111111111111--1111-1----11111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1-111111-----------------------------------------------111 11--11--522-------------------------------------------------------------------------------------------------G2------------------------------------------------1----------------13347232743474-433911113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.310 VC0467-like
[ 629] 11111111111111111111111111111212111122111111111111111222211121111111 -1--1111111--1---11-1-----11111-----1211-1-11-1-1----11--1--13--1111111---------1-11-1--112---------2---21111---------------11-------1-111111112112212211---------1---111-------------2-11111----11111-11-1112-111----112---1-11-1111121------------------------------------------------------------------------------------------1-111-----------1--------1--1---1111-1-111--1111---12------------22-------------------------1------1----1--1-----------------1---------------------------------------------------1----111111--------------13--111-----2-----31111---11---2---------11-111211-121-11112-11111112111116511--------------------------------2-----------------------1---1111-------1-1---1222222222-2112222232222221222---131111-21212122211112-3212221-------------------1-1111111-2-----------------11121----11-2223231-1-1------------------------------1111111----------1--------------1---------------------------11-1111111121- 22--111-4111--1--1----------------------------------------------------------------------------------------122211111211111111111144D1-112211112112111121221211111321311-1111112111119111122---2-1-1----2 ----------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.261 Hypothetical protein PH1602
[ 630] --1----------------------------------------------------1------------ -1--1-1------1-111---211-122121-22-42412--------2--1--------2-----------1112111-12-11-111--1------------1-1----------------------------------11-1-----------1--------------------------------1-1-55555111123223-1-4412-13-111---3---21311212221132442421--2-2----3-11--312223-2111-33222-1-1---------11--11244441122113------------2-112--231142221441111-151----2--11111----1---------211-------1-1-64311111111-111-111-21-11631111-2114------1-121-1114734314111111111--1-----111111111111--11--2------1-11-12-1-11--1----1------11-213--11------1----1-11--1-211---------1----1-1-1-1----1----2---111---1------1---2--1---1--1---1-------------------------------1------1-1---------2---------3---2--55--1-2---4---214-1-411-----1-1-----11---121----1----------1-2--111-1111-----1------------1--1--11-------------1-1-1------11----12-12-----------------2-----------1--------2222--------------------1--------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------- ----------------------1----------------------------11------------------------111-2111---111111111-11--11-111111111-11--11-1-11--11-11111--1--1-11--111111-------11------1------ * d.183 Major capsid protein gp5
[ 631] -------------------------------------------------------------------- 111-------------------------------------------------------------------------------------111111111--1111111111---------------11111111111------------------------------------------------------1111111111111111111111111111111111111111111-11111111111111111111-1-11-----11--11-1--1----111-----11111111-1-1-----------------------11111111111111112111111111111-111111111111111111---11-111111111111111111111111111111111-11111111111-11-11111111111111111111111111111111111111111111111111--1111-111111111111111111111111111111-11111111111111111111-11111111111111111111111111111111-11111111-111111111-111111111-----11--------------------------11111-1121-111111111111111111111--11111--1---11111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111212222222212222-222---------11111111111111111111111111111--11111111--------11--------------------------1------------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.244 Cell division protein ZapA-like
[ 632] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111111111111--111111111111111-111111111111111111-1111111111111111111111111111-11-11111111111111111111111111111111111111-111111111111111111121111-11111111111111111111111-1111-1-111111111111111-----------------------------------------------------------11111111111111111111111111-111--11111------1111111111111111--11111111111111111111111111111111111111111111111111111111111111111--111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1--------------------------------------------------------- 22--111-411-1111111111111-11111111111111111-111111111111111111111111-111111-111111111111113111112112121111-11-223121211111111111-151-1131111211111111-12111211122112111211--11111116--11111-11111111112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.218 YgfY-like
[ 633] ---1--------------1----4-----1--11336432233532-444767412-1-21---1--- ------------------------------------------------------------1-----------------1111---1--1111-111----------------------------21112111112-----112---11-111----1-1-1-----1------------------------1-111111111111111-----11112------------1-------------------------------------------------------------------------------------------16248332333333244332113222111111467841112641122-1--2------------1------2------------------------------------------------1-------------1------2----------------------------------1-----1----11-------1------11--------------------------------------------77532422222321543322343-----124-2211----------------11--11111--------11111-1111111111111-----1-------111111-1111111111-111111111111111111111111--1111111111111111111111111--111111111111------------------1111-1-------------------1-----------------------------112-----11111----------------1---------------1---------------------------1112111111---- ----1------1--------------------------------------11-1-----------11-1-11---11-1------------------------------1----21-1-1-1--121213B1-213--1-11111-11--2---111-----1-------------52-5---1-3212-2211----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.26 Prismane protein-like
[ 634] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------3--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------1-----------------------------------------------------------------------------------------1----1vGRIQnC5242633654347P3-64833315-3434332392313VA7E3115E6X78CGMHH55------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.7 Lipovitellin-phosvitin complex; beta-sheet shell regions
[ 635] 11111111111111112111111111112-11111111111111111121222111111111112111 11--1----------1111-11--1111111111111-11----11-------1--------1-1-1111-------------1-1----------------11-11--------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1111-----------------------------------------------------------------------------------------------------------------------------------------------------111111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- 1111233-311111322332222222222222222222222222222233223333333333111111-1111111111111111112232223322222212112135352445422233443672616L6-4383333323521332232-224223132-331131-612331221G1112311223431123231 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * a.235 ATP-dependent DNA ligase DNA-binding domain
[ 636] -----------------------------------------------1-------------------- --2------------------------------------------1----------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1----------11---------------------------1-1-1---111-2-1----3--1--111-11-----------1----1-------------------------------------111-24111124444422346666154142221--1-12-1--1---3--------1------------31----------1----1-1-11-1-----13---1----------1--------------2-1-11----21-----1-----1-----1----11-------64-B2211223156743-1-131-433425311111222277FB72944543444334342311----21-1989999789A8---1-----------213----1----------1111111---2-5635814326523-374----------41312222212311--1-2--222---------------------------------------------------------------- ----2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.157 Hcp1-like
[ 637] -----11-111111-1----------------11111111111---1------11-1-------1--- 1-1-----111---------------------------3-------------------------1-3-1------------2----------------------111-3-----------------------------------11---------------------------------------11---1-----------------1-22-1------11--------1----------------2----1------1---2211----------------------------------------------------------1-------------11----1--1------22---------------------------1-411--11211-11111111111---2--2-253--23312133336431--1234-1--122--------------1------------------------------2--1--155362332322111-22221111-122-2443------1-11--2-441-------1--------------------------1----------------1----------------------------------11--1--------------------------------3-21---3225355533-233345433325333333423313--13-3221333332322232212221------------------------------211211-1--1-11111----------1-11111411-3231-111-----------1---------1-------------------1-------------------------------------------2---------1-- ---------------11112111212111111111111-1111111--12111111111111------------------------------1--------------14-12211-------------------------------------------1231111136313222----17111-----11--11----2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.122 L-sulfolactate dehydrogenase-like
[ 638] 111-1211111111121-221322-11--2--1-111111321124631-12112111211---1--- -11-2-------------------------------1------------------------1------1-------------1----------------------------------------1--------1-------111-11-----------------------------------------11----1111112111111111-11--112--1------------------------------------------------------------------------------------------------------1----1111111-1--111----------11--343--11-1-1111----1--11------1-11122122212------------11111111-1--1-------11--11-1---1------1------------1-11------------------------------------------------------------1-----------------1-------1----111111111------34412322-32112-1111-1-2211-1-122---------------------------111111111111111111211111112121----11-------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---------------1111111111111111111111-111111111111111111111111----------11111111111111------------------11---------------------------------------------1-111--1- --22222-1112------------------------------------------------------------------------------------------------9411111121112-1121-516D1-21511--112111111111-11---1-1-121-13112---111114212121111-111212123 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.56 YaeB-like
[ 639] ----------------1--------------------------------------------------- ------------------------------------------------------------------------------3--------------------------------------------------------------------------------------------------------------1----------1-------1-11-1-------1--434444----------------------C1-15D1131533--6814422211132344443334443343444433333333343333331113333---2A-----1-3-2-6---442---3-3--------------111-2121----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111111--------1-11111-1----------------------------2---------------------1----1--1------------311133-3444354543-3233444443454333334433122213432333442324223321133213-222222222222111---------------2222121----2111----------------------------------------112--------12-----------------1---------------------------1---------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.38 PTS IIb component
[ 640] 11----1111111111--1-1111111111111111111111111111111111111111-111--11 ---1211111112111111-1111111111111111111111111---------------22221212221----------11-----11-1-111----11--1-1-----------------11111111111111111121-111111111111111111111111111111111111111111---11--------------1--1-------1111---------11---------------------------------11---------------------------------------------1----------1-11-------1-111111111111---1111111111--12-----1111-211-111-111111---2122211111111111-21111111121-1111111111111122-111111111111111111-11-1111-------------------------------1--------1111111111111111111111111111--1112311111111-111111111----------111-1211-11111111-111211111-----2-11-------------------1--------2-111-11-11111-1111111111111----11-------1---1--1111111111-111111111111111111-222--11-1111111111111111-1111111--1------------------------111-1---------------11111---111111111111111111111-------------11111111111--11111111------1-111111--------1---------------------------11-22-1-----1- ------------------------------------------------------------------------------------------------------------3-------------------------------------------------------------------2-1---------1---1-----1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.39 Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)
[ 641] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------8JKDCEA7886674GB5B6KbC-A7G5876D45B848545975E7F8794EM43445733D6864------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.164 SMAD MH1 domain
[ 642] -------------------------------------------------------------------- --1---------------------1------11----------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111------211111111111111111111111-1111111111--11111121112211---111111111111111111---1-1-1------------------------------11111-----111111-----11--1111-111------------1-----------1---2----------------1---------------------------------------------------111--11---------11111---1111-1--1---------------111111-1111111111-1121111111111111111-11--1111111-11111-1111--11-1111-----------------------11111----111111111111--1111111111-1--1--1111----1----1------------1------------------------------------------------------------------------------------ ----3-1-------1222232222222111111111121111111143353223222--111221111131111211-11233323---2322-13-111112142-185211222211---11211216D1-313211-11112-11--1112221211-11135-11111121-13111116126W8252-165551 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.124 Ribonuclease Rh-like
[ 643] -------------------------------------------------------------------- 111---------------------------------1------1-1------------------------------------------------------1111-1111-------1111111------------111-----1-------------------------------------------------111111111111111------111-----11-------------------------------------------------------------------------------------------------------------------------------------------------------1111---------------------------------------1--1---11-111----111------------------------1---------------11--------------11-2------11111111111111-1111111111111--11111111112-11-------1--------------1-----------------------111111-----------------------------11-1--1111-1111111111111111111---------------------------------------------------------------------------------------------------2-----1111--1-------------------------111-11111111111111111-------------111111111111111111111---------------------------------------------------------------- ----111-21--211----------------------------------------------------------------------------------------112-1-386A57A8443355564365ER6-866535355546443434544667565563444456-F3511111-----111------1-311-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.178 Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
[ 644] -----------------------111112121---1111111112112-111111111111------- -1111--1111---11111-11--111111111111-111111111-21---1111-1--11111-1111--------1---211111111111111--1--1111111111111111111111---------1-11111---2111211111111111111211211111111111111111111111-21333333333333333322223333421121111111113211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112222222222222222222212122112112211222212211111111111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------123-3122112221132322321222221114----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111111111111111111--11-11111111-1111---1111111111111- -------------1------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.320 YojJ-like
[ 645] -------------------------------------------------------------------- 113--------------------------------------------------------------------------------11222333313331--344434542311111111111111111111111121-----------------------------------------------22211221-----------------------------------------------------------------------------11--------------------------------------------------------------------------------------------2--------1-1112111----------------------------------------1---------------111111111111111111111122111111111111111--111111111111111111111111111111111111111111111111111111111111111111111211111111211111111111111111111212332222222222121211111211-------------------------111111111111111111111111111111111-111-1------11111111112111111-111121111111111111111111111111111111111111111111111111111111111111111111111111111112221112111121111111111---1111111111111111111222222222111111111111111----------------11------1111111111--------------------------11111111111112 -----------------------------------------------------------------------1--------------------------------------------------------------------------------------1----1----------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.48 OmpH-like
[ 646] -------------------------------------------------------------------- -11-1-1----11111111-111111111111111111111111111111111111111111111111111-111111111111111111-----------11----1----------------11111-1-1-11111111111111111111111111-111111111-11----1----1111111-11111111111111111111111111111111--11111111--------------------1---11-------11---11--------------------------------------------------11111111111111111111111111111111111111111111111----1----------------------------------------1------------------------------------------------------------------------------------11111111111111111111111111111111111111111111111111111111111121111111111-11111-1-11---111111111111111-11-------------------------111111111111111111111111111111111-1111111111111111111111111111-1111111111111111111111111111111111111-11111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1----------------11----------------------------------1--- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------1------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.229 MesJ substrate recognition domain-like
[ 647] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2111222-2---22222222222222222222222212222212222222222222212222222222-2222222222222222222223222222222212222-23236844455346554DA463KY5-B69342373467547244346184532332223223222232----------32232222-24233 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.43 Subunits of heterodimeric actin filament capping protein Capz
[ 648] 11111111111111111111111121122212111111111111111111111122221221111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 22222221622222212222222222222222222222222222222222222222212222222222222222222-2222222222222222222222232224121143222232131121582213G3-3371222222221231121122422225522221822434222222F2222264572352222222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.59 Zinc-binding domain of translation initiation factor 2 beta
[ 649] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------2-----f***-*c------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.52 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
[ 650] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1111---------------------------------------------------------------- 4423112-41-11-121222222222122222221222222212222222222222221212222111-23221222-3322222222232213222121222221-2813453542332333344173BO6243633323333111322533B322331471133-42222933156-354444644E2C42112221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.76 GYF/BRK domain-like
[ 651] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------W***-*L------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.143 NAC domain
[ 652] --------------------------------1---------------2------------------- 122-2---------11111-11--11111111111111---1-1--12----1111-1--111-1122221----------11--1----------1---1---2-1----------------1---1------2--------1---------------------1--1-----------------------111111112-112121111111111---2-1122222131--------------------11-111--1-1--111-----1-1-1----------------------------------------------1--------1-----------1---1-1--21111-1--1-----1--1--2111-----111-1--1-----22222212222-11111111-11--11211-11111--1----1-----11--------111----1-----------------11----1------1111-122-12122211112122111111114112123--22311111-11111111---11---------2-11-1211-11-22-2111---------111121-1-------------------------1111-1----11-1111111111111111111-------------111--211111111111-111111111111111111121212111111111111111111111111111--111111111111---1-1-1-111--1211-------------------------1122212222111111111-------------111111-11111111111111--------------------------------------------------1----------1-1 -------------1---111111222111111111111-111111111121--1---1----122----1--211------22212------------------------------------------------------------------------------------1-----------------1-----1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.48 Ada DNA repair protein, N-terminal domain (N-Ada 10)
[ 653] -------------------------------------------------------------------- ----1--------------------------------------------------------1--1---1-------------------11----------1---21-------------------------------------1-1--------------------1121------------1-2-------------1------11---------1---------------------------------------------------------------------------------------------------------------------------------------------------------1---------------2112-----------------1--------223--133721154-3--1---31-222212---------2-2------------------------------------1--1--------------------------1---11---------------------------------------------------------2----2----31----1------1-----------------------------------------1--------2----------------1221111112--11111112-112121222--------------------------1---11-----------------------------11-----------------------------------1------1--------------------------11--------------1---1366-------------------------------------------------- ----554---1-1121211122222222222222222212122111--111113111111111--------------------------12-212--------1-1-6336333341233233243243BO6-3352332334522413334-3442332233441131125447----------3325134--5335- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.297 WGR domain-like
[ 654] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4311112-K87222211-1111111-11111111111111111111-11111-111111-111-1111--1--11-1---1-11--111111111111111-11121142D465453-244332772338F5-4372335423742324333342543344322822723C27221333X11123577H1641257848 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.39 DLC
[ 655] 111-11-----------------1--------1-11111111111-1131111111-1111---1--- 111-1---------1------1--11-1-11-1---1---1111----------------11--11---------------1--1111--------1------------11111111111111111111111111-----111-1--1111------------111111--------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1111------------111111111111111111111111------------1111111111111111111111--11111--11111-11--------1---1111----------111111111111111------1211----------------------------------1---1-----121----11----1-------11111111-11111-11111-2321212111111-111--------------------1-11112111-----1-211111-1111111111111---1-1-------111111-1111111111-111111111111111111111111---1111111111111111111111111-111111111111--1--1---1211--1--1111111----1111----------11-111-11-1------------------11111111111111----------------11111111----------------------------------------------111- 1---11--211-11---111111111--------------------11111111111-1111----------------------------------------------1121-1--1111111-1111-1B1-1121111111111-1-121-2-1111----1---11111111-1116111223233-31------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.206 YggU-like
[ 656] 11----------------1-111-------1-1-11111111111-1-111111121111-------- 111--------------------------------------------------------------------------------11111--1-------------1-------------------11111111111------------------------------------------------------1-21111111111111111222222111111111111111122--------------------1-1-11-1---111111---222------1-------11---1---11111111111111---------1-1-------------------------11------1---11-1111--1--1---------------------------------------------1------------------111111111111111111111-11-111111111111111111111111111-111-----11111111111111111111111111111111111111111111111111111111111111111111211111111111111111111-1111-1111--111111111111111111111111111111111111111-11111111111111111111-11111------11111-11111111111-11111111111111111111111111-111111111111111111111111111111111111111111-----1111111111111111111111111111111111111111111-111112------------111111111111111----------------1-----------------2------------------------------------1-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.195 YutG-like
[ 657] 11112111111111111111111111111112111111111111111111111111111111111-11 --2---------1-----------1------1----11----------------------------1--------------------------------11111---1---------------------------11111---1-----------------------------------------------------------------------------1--111111---11111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111-------------------------------------------------1------------------------------------------------1--------------------------1-------------------------------------------------------1--111---------------------------------1------------1--------------1---------------------------11--------------------------------2----1-----------------------1----------------------------------------------------21-------------------------------------------222221111-------------------------------------------1--------------1111-1111111111------------------------11111111--1--------------------------------------1 ----221-211122111112231445411-11112111111111111111112611111111111111-1111112212211111111112111121111111312135222323211121-1111241381-21311121211111111211112111--11111121121111----------33562211111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.179 Substrate-binding domain of HMG-CoA reductase
[ 658] -------------------------------------------------------------------- 133------------------------------------------------------------------------------1-----------------16---713-------------------------11---------5-31--11---11-----------1-2--------------------------------------------------3---------33-----------------------------------------------1-1-------------------11-1-11-----------------------------6---------------3-125-----------------3---16318--3423----11---------------2-11-113-----1---1----11---2-------31---------12--313------------------------------------1--1---2-13----11-12----1---1-------51-3--64------1----32-122222-------1--------11321-3----5-11--11-----------------------------------31---2-111-1--1--114-11-1---------------57111222-22-22--3223-42123332112113---43KN-----21131-1632-1--2----1--322212222211---3-----------5-2-----1-4-----3------------3--2-3442----1---1------------------------1-333333441212--------22-222----1--------------------------------------1-2 ----1--------------------------------------------------------------------------------------------------------1----------------------------------------------------------------1-------------------1---- ---1-2-----------221---2-------------1-2-2---------------------1-------------------------------------------------------1------------------------12------------------1---------- * d.231 Receptor-binding domain of short tail fibre protein gp12
[ 659] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------A7788D366384C5RE485YfC-G8DA542834974862575244A4592222644A77724S21----------1------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.1 Insulin-like
[ 660] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--111-735--112221212223-111-22134423333333242224212122323223433322-321232-322223322311114322332232221442-23141341314421244G2125GB7-5342324524343422115122132531-2-3324353-12314239122227334434-1223-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.17 Cysteine alpha-hairpin motif
[ 661] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------1-1------------------1-1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--111-----------------------------------------------------------------------------------1--------------------------------------------------------------------------1----------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------4474444555554455455455555555555555554554555555555556644435556556525446666544445445553333544DEJ---------------------------------------------------------------------------------1-5--------- ---------------------------------------------------------------------------------------------------------------------------------------------1-11-------------------------2---- * d.34 DNA-binding domain of Mlu1-box binding protein MBP1
[ 662] -----------------1-1----111----------------------------------111---- 111111-------------------1----------1111----1111----111111--11121-1111------------1-----1111-111----11111---1--------------------------111-----1--------------------------------------111-------111111111111111111---11111111---------1-1111111111111111---1-----------------------------1---1-------------11111111111111--11------11---------------------1---1-----------1---11-12-1--1111-------111--------11111111111---1--1--31--211122122211---11--21-11111--------1--1--11--------------------------------11------1111111111111112221212112322--111--1--1-2-11-------1-----------1--1-2-1-------------------111111-1---------------------------11-1--111111111111111111111111-------------1-11-11-------------------1----------111--11-111-11111111-1-11---------111111111111---1-----1111--1-1---------------111211--111-1111111111111-111----------111111111111111111111111----------------------1---------------------------11111-1------1 ----11-----------------------------------------------------------------------------------------------------1122331223123111313-32341-322--2-31111-222-12-1113211321211-----1132--1----------1-----21231 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.51 Urocanase
[ 663] ----------------------------------1--------------------------------- --1-------------1---------------------1--------1---------1----------------------------1----------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------1---------1-----------------------------------1----------------111111111111----------1--------------------------------------1------------------------1-------------1-2------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------2--1-------------------------------------------------------------------------------------1-------------------------------------------------1-------------------------------1-----------------------------------------------1---2----------------------------------------------------------------------------------------------- 1-11--3-2112--1--14----1---1---2--11--3-3--11--------51-111---22--------1--2--25-1---1----42---3-2---2-112--3162-273D74985-334A269o1242584773818332A6418B571-451132--16---2-12-----9---1--49D-1421D5321 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.220 Metal cation-transporting ATPase, ATP-binding domain N
[ 664] --1111----------12111111--------11111111111111111111111111111---1--- ----1--------------------------------------------------------------11--------------1-----------------------1----------------1--11--11-1------------1---------------1----11-----------------11-------------------------------------------------------------------------------------------------------------------------------------1-1-1---------------------------1--1-1-1------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-----111-212112221--------1---------------------1-------11111-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111-111---- 12----2-311-2221111-221121111111111111111111-1111111121112121111111111111111111111111111223213223222223111-22142522232312123753413B2-2252322322211222312343332211122222623232311334I3442232351421133551 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.50 AF1104-like
[ 665] 11211111222121232111111212211111111121111111111211111111111112111111 -------1-------1-----1--1--------1-2-1-1--1--1-1-------11---21--1-2222-----2--------------------------------------------------------------------11-------------------------------------1-1---1-1------1-------1----------------1---------------------------------2-1---22--1212-1--113-1---1----------------122--122-1------------2-------------1----1-----8-1---------2--------------1----------1--121----1--------------11--4-1---1--------------------------1111111111----2----------------------------------1--------11-------------------------------------1-------------------------1--1-----4-----------------------111-112111111111111111-1------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------1--------------------------------------------------------- 1121111-31111121111111111111111111111111111111111111111111111111111111111111111111111111112111111111-1111111312121-11111121113121171-11121121111111211211-2-1-113111-11111212111111959-1111111121111111 ------------------------------------------111---------11-----------------------------1---------1------1-1----------------1-------1111----------------------------------1------- * d.264 Prim-pol domain
[ 666] -------------------------------------------------------------------- --------111---------------------------------11-----------------11--112-----2------2----------------------------------------------------1--11--------------------------------------------------111111111111121112111111111-11-111-------211111111111111111111111-11-11-11111111-1--111111111-1---111--1-1111----------------------1------------1-11---11211211-1--1----1--11--111-1----2---------1-111--------11111111111----------2--211432244422-1----1-----2----------111---------------------------------------------111111-----1111------112---------1-1---12111-------11-----------------------1------------------------------------------------113-----1-1-------1------1-----------------31111112222222222-2222222222222212211222111112222222222222222122122221-122222212222----------------112221---22222221----------------1111-1111-111----------11111111111112-------------------------------------------------------1-----121--1111-11- ------1-------------------------------------------------------------------------------------------------------412121--1--11141-11452-2121--121-11--1--1--11-------1111--------1-----------------------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.133 RbsD-like
[ 667] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2-1122122---222222222222222222222222222222222222222222222223332222222222122222222122222222222231222222222321111333347223333274142EJ5-83722333233333-133235343341-1922215233331222-2F222324323261------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.56 Transcription factor IIA (TFIIA), beta-barrel domain
[ 668] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------ACFAF966555687HB676VyE-C8G3656B479736454853A76766-422343-12361131------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.200 Integrin beta tail domain
[ 669] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------2222211111----------------------------------------------------------------------------------111111111111111111111111111111222------1112222222222222211122---------------------------------------------------------------------------------------------------------------------------111211111111111121111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111----------------------------------------------1------------------111---2---------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2 ----111-632-1111111111111-11111111111111-111111111111111111111122111121122211-11122222-1111111111111111112-1212363242111111131111372-11-1-111111-1111111111111121121111411111111111I1121111121211121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.267 Hypothetical protein SAV1430
[ 670] ------1--------1--------1---1--1----------------------------------1- ----1--1111-111--11-12--1211111111111211-1111-1-----11111-------1-3223-----1----------------1-------1---11-------------------------------------111-11--1-1--1111-1111-111111-11111-1-1--1-------1------1---------1---1----1-1----------1-11111111111111111-1---------------------------------------------------------------111---------------------------1-11-------------------1---------------11133---1111122222222222-3413313211--111111111111111--111111111111111111----1---------------------------------------111-1111111111111211111111111111-1111111--111111-11-1-1-1---------1-11--------------------------11-1--1----------211111111---------1111---11-------1--------------11-1------1---11--12--------1---------1--------111--111--------------------------1111111-111111------------1111111----1111----1111111-2-1-11111111111111212-----------11---------------------------1----------------------------------------111-----------1-- -------------1111111121111111111111111111111111111211211111111------------------------11112111211111121221--2-1----------------------------------------------------11--------2-----8111--1-121111111112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.8 Urease, gamma-subunit
[ 671] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----22-----2-------------------------------------------------------------------------------------------463----------------------------------------------------------------------222723221e*u*-*N------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.79 WRKY DNA-binding domain
[ 672] ------------------------------------1------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------1----------------------1-11111111------------------------11--------------211----------------1----1-1---3------111111111111111111111111111111111-11111111111111111111111111111111111111122222222111211111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111-1--11------------1--11-------1--------------------------11111111111111111111111111111111--112111--11111111111111111111-1111111111111111111111111111111111111111111111111111-111111111111-111111111111111111111111111111111111111111111111111111111111122222222211111111111111111111111111111--1-----------------1---------------------------1---1----1-- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--2---------- -------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------- * d.33 SecB-like
[ 673] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111--3-1--12111111111111111111111111111111111-111111111111111111111-1--111------11111---24212221111211222-2N-E666667333244384384BJ6-757333153435244214227234346543742232313443222-21-12226591823311112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.224 Glycolipid transfer protein, GLTP
[ 674] 11111111111111111111111111111111111111111111111111111111-11111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11-1111142211111111111111-11111111111111111111111-11111111-111111111-11-11112-21111111211121111111111113341121211111-1-111119U1O2Dg9-28O12119-124-111-2-111121111111111311112111111F1111153231311111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.29 Ribosomal protein L31e
[ 675] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2----------------------------------------------------------------------------------------------------2--D889C6B4443343664937M6-76B433343454244436449464324429227122-52D22-5529221127559-E4896EA84 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.53 TAZ domain
[ 676] -----2----------1------1----------1--------1------21211111111---1--- ----------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1-111111111111111111111111111111111-11111111111-11111111111111---1111111111-------------1-111-11111-----------------1111---1--111111111111-1111111111111111111111111111111111111111211111111111211111-----1---------------------------------------------------11---------------------------------1111--------------------------------------------------------------------------------------------1111111111-------------------------------------------------1111111111--------------1111111111111111---------------------------------------------------------- ----11--211-1-11-1-11111111111111111-1111111--11111-1111111111111----1--111------11111----21-111111111-111-11-4312212112122243242966-4242222322222211222-2222222--1111-111-1321111121111112-11211111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.103 MTH938-like
[ 677] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111--------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------1--37D7BE37755766EA786RrA-89957779579D37476864B6735722626111-124---3------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.90 Transcription factor STAT-4 N-domain
[ 678] 111111111111111112222221-11-111-111111111111111111111111111111111111 -1---------------------------------------------------------------------------2--11-11111----------------------------------------------------1111--------11---------------------------------11-------------------------------------------------------------------------------------------------------------------------------------11-11------------11------1-----11111111211111111---1---------------------------------------------------------------------------------------1-1---------------------------------------------------------------------------------1----11---------------111-111-111111111-1112111121111--12--------------------1-11111--1-------1-------1----1-1--11-----11--------------------------------------------------------------------------------------------------11111-1-----------------------------------------------------------1--------------------------1---------------1---------------------------1111111111-1-- 11--111-31111111111111111111111111111111-11111111111111111111111111211111-1111111111111111-111111111121111-1212112111123222233232573-235222222222222222212223221111111121151111111-6---1-211311111-111- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.309 AMMECR1-like
[ 679] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111-----1111132111111--11-111111111111111111-111111111111111111111111111------------111-111111111111111111111111-111111111------111111111111111111111111111111111111111111111111-1111-------111111--------------------------------------------------------------111111111111111111111111111---11-1--------------------------------------------------------------------------------------------1-----111111----------------------------1111111111111111111-------------1-----111111111111111----11---------------------------------------------------------- 11--111-311-1111111-111111111111111111111-111111111111-111111111111111111111111111111111211111111111111111-11-1111121121111121-111A1-13111-12-112-1111111111211---12111111211111111A1111111-21111111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.146 Ctag/Cox11
[ 680] ---1--11111111111111111111111111111111111111212411111111111111111-11 -------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------1111111---------------------------------------------------------------1--------------------------------1--1--111-1-1-11111111111111--------------1111111111-1--111122122-----------1---11---11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111--------------------------2-------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------12------------------------------1--1----- 1111211-311111111111111111111111111111111111111111111111111111111111111111111-1211111111112111131111121111111121511312413222223232H2-2432233242223222223133222224421111211111211111F1111121111211111211 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.40 V-type ATP synthase subunit C
[ 681] -------------------------------------------------------------------- ---11111111111-1111-111111111111111111111-111111-1-11-1111--111--1-1111--------11------------------------------------------------------1111111111211111111111111111-11111111111111111-1111111-111111111111111111111111111111111111111111-111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111-11---111111111111111111111111111111111-11111111111-1111111111111111111111111111111111111111111------------------------------11111----------------------------------------------------------------------------11-1--111-111111111111111---1---111111--11-1111--1-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------111111-111111111-11--1-111-------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----221---------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.192 YlxR-like
[ 682] -------------------------------------------------------------------- ------------------------------------------------------------------------------------1111-----------------------------------------------11111---1111111111111111111111111111111111111111111111-------------------------------------------------------------------------------------------------------------------------------------111-21111111111111111111-1--111111111121111111111-------------11111-------111111111111-1121121111--111111111111-------1-------1111111111111-1------------------------------------111111111111111111111111111111111--111111111111111111---11111111111-111--1-1-1----------------------111-----------111111111-11--1211111-1-11111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111------11-111111---------------1111111111111111111111111111111111111111111111111111111111111111111------------------------------------------------------------ -----1------------------------------------------------------------------------------------------------------2------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.71 Cell division protein MinE topological specificity domain
[ 683] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----1-2-212-212111-11111111111111111111111111111111111-1111111111-1-11--11-1111111111-1111111111111111-122-15348746953432343852519U4-42A1321533243332243274523424332212733642221222H111226598162--12112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.104 P-domain of calnexin/calreticulin
[ 684] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------1-1-346668AF6KI7ICWaK-HEAH997825C4A8I67958D35181---------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.5 RNase A-like
[ 685] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----221-----112212222222222111222221122222221222221222222222222222222222122222222122221222211131111122221312221333345233233394331FI5-946123322332332133-2513324131721214234331211-2C211224323262------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.32 Transcription factor IIA (TFIIA), alpha-helical domain
[ 686] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11-1422-835-23211121111121111111111111111111112111111111112211111111-11111111111111111111121131111111111221212212111-114412121-212D3-12213381111-11E4611-3-11111211111-F143GO121111E111238E7E1L33443331 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * a.157 Skp1 dimerisation domain-like
[ 687] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11-1112-522111211111111111111-11111111111111111111111-11111111111111-1111111111111-11111113111131111-11112-15233332262231443883C4Gc8-948323274443343134335376423351221-2142122212111111-122361511111112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.245 NSFL1 (p97 ATPase) cofactor p47, SEP domain
[ 688] 1111111111111111111111111-111111111111111111111111111111111111111111 ----1111111-11-----------1----------1111----1--------1-1-------1111111--------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2212112-62222231111111111111-1111111111111111111111111-1111111111111-11111111111111111111-131222122211222212435223531212122-42122352-222111-222222211-3-221223213-33241334-22323222E2223343451541-21113 --------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.131 Peptidyl-tRNA hydrolase II
[ 689] 111-11------------------34433333-----------------1---1--2---1---1--- 111--------------------------------------1--------------------1---------------1-1-11-----------------------1---------------------------1111111121-------------------------------------33322--112122222322234233422111123211131222222228321111111111111111111----11---------1111111----11111-11--11111111111-------------1111111111121-2111111111111--122221-11111--2214--2122---1--1-1-----11111--22111--1---1111111-111-1111111-11-11111111121111--------------222222221111---------------------------------------2222-111111-----11--------2-1122--------1--1---1-11---------------------1-1-111-12111-1212212-2------1-----------------------------------------------------------------------------------------------------------------11-----------------1--------------------------1-1------------------------------------------1-2-2111--------------------------------------------11------111111111-1-------------------------1-111-2----11- --------111--1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.60 Thermophilic metalloprotease-like
[ 690] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5535--2-D46------------------------------------------------------------------------------121--1-111------1-2M35454725221833365362AJ3-637124242443133234217143331-22242-7351-153-556J222632435-417A797A2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.314 PUG domain-like
[ 691] 1111111111111111-211111-111--1------------------------11111112221122 2222121111111111111-1111111111111111-1111111-----11-------1111--1111111--------111111111---------------------2222222222222221111111111122222111221------111111111121111111111111111111-1-11111---11111--1---------------1---------------1-----------------------------------------------------------------------------------------1112-1111111-1--1221111-1-11-1-21112221111122211--11----------1---------------------------------------------1--2----111------11111111111111--1111111111111111111111111111111------------------------------------------------------------------------------1-111111111111111111111111-221111111111111111111111121111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1122221111--2-11--------------------------1111111111-1-- ----11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1--------1-1------11-------------2---------1------------------1----------------------1-----1-----------------------------------------1----------1---------------------1--- * d.207 Thymidylate synthase-complementing protein Thy1
[ 692] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----22------2222212122222222222222222222222222222222222221222222222212222222212222222222224-22122222221222223246653622221123311435L3-447222152282132312-14211223432222222242222---2422-1-3355221112222- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.65 triple barrel
[ 693] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--222-311-11-222222222212222222222121222222233222212122222122222222222222222-231222221123222222122231223-21114441322-12323331548E3-54722214114413112211A31132---23221612512411122811132355324411112-1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.51 Cytochrome c oxidase subunit h
[ 694] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----56--21--2221-22111111-111122222-2111111111-12211111122-212---------------------------121-1112122111211-B2152221242212222342424G2-3231223323221212-3114232121111121-1111--1-2688KDDC9895591793467572 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.166 RuBisCo LSMT C-terminal, substrate-binding domain
[ 695] -------------------------------------------------------------------- ---1------------------------------------------------------------------------------------------------------------------------12121-113-1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------11---1-11111111111113-------------------2---5--------1---------------------------------------------------------------------1----11-2-------1--1-------2131121-1--1111---2-1111111---111---------1-------------2-----------------------------------231221112221111111111111111111--11111------22111222222222222-2222222222222222222222111112222222222222222122222221-111111111111---1-----1111123231111121111111112222222222222222332333333222211111111112222222222222211214111111111--1--------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------1----1------------------------------1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.199 YgfB-like
[ 696] -------------------------------------------------------------------- --12------------------------------------1---1---1--1-1--------1-1-------------------------------------------------------------------------------1----------------------------------------------11---------------111111---1111111------11------------------------------------------------------------------------------------------11111111111121211111---1-1--1221-111211111111111--114--------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------11-11111111111----1111-------1--111-111111111111111111----1111111111111111111111111111111-1111111111111111111111111-11-1111111111111111111111111111111111111111111111111111-11111-1-1111111122222565611112111111111111-1111111111111112323234133351563---------11111111111111111112111111111--111111111111111111--------------------------1-11111111-1-- -------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.151 CsrA-like
[ 697] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-----------------------1---------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------6---3-------------------------------------------------------------------------------------------------3-J7J7EA7324334353344Nc7-4462434A33523423442266544488E-2712973337H------------------1133331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.83 Guanido kinase N-terminal domain
[ 698] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2111322-1---22211222222212122222212222222222222122222222222222222222222222222222222322222-2212251122-11222-21253333232-1123163333484-344334342343232123243233331122322132352322-22232222122-4233111221- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.252 Mediator hinge subcomplex-like
[ 699] -----------------1----------------------------------------------1--- --1---1------------------1-----------1-2----3-1-----232--------11-2---1-----------1-----------------------1-2-----------------------------------1-111111111111111111111111111111111111--------------------------32112------1-2---------1-------------------------------------------------------------------------------------------11--11-1111-1--1--1--------1-11---------11-1--11---1---------1-311----21--12221221221---2--6-2-1--311-3364333332---1111-121-1--------3------1-----------------------------------121113221212111-22231111-11-21122-112------2-3221---1-------------------------1-------------------------------------------------111-1---------------------------------1--------21--11--2122211--111-211-1-2-11111-4432311-2-2222221221212211-----1--111111111111----------------22---3-3--1-11221-----------------1-1---1--121-------------------1---------------------------------------------------------------------------1-- ---------------21--21212121-----------------------1222231-----------------------------------1-----------------------------------------------------------------1------------------1-------1131-11------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.146 YgbK-like
[ 700] -----------------------1-------------------------------------------- ---11--1-------------1---1------1111-211-1-12----221323--1------112232----------------------------------------------------------------------------------------------------------------11------1144444444324344445344344432223311------431-------------------1-1-22---------22---------111------------------111111111-111---------1-43-21111111---21112221-2--1-1-12344121-312111-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------221---------111-----1-1----1---------------31221212222222222-2232222222222-1211222222---323123333333331321-11112--2---------------------------11---------------------------------------------------------12222211122--------------------------------1----------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.123 Sporulation response regulatory protein Spo0B
[ 701] 11-31111111111112112111-4222223211111111111-----1----1---1-11---2-11 -11-----------11111-11--1211111122221121-2-1--------2-------1-----112-------11--1-3--1--11-1-----------11------------------------------111------112212221122222222-21-22121221111211212----11--------------------1-------1----1-111211-1---------------------------------------------------------------------------------------------------11--2------11111--------111----1-1--1----4--111111111211121111111111111111112-33233231432131132212221111-11212----11-111111111--11-22------------------------------------11--111--2--------2------12--11--------111122134------1-2------------1---------------111111111-----1-1-1-------------------------------------------------------------1-------------------------------------------111---1-------------------------------------------------------1----------------------------------11----11------------1---------------------------------------------------------------------------------111---- ------------------------------------------------------------------------------------------------------------2-------------------------------------------------1-------------------1H--------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.125 Creatininase
[ 702] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111221-3111222222222222222222222222222222222232222222222222222222222122222222222222222222222327222235222212212221132111221133152RJ4-722-12121111212--11132211111-11111311112411211D11-1121232111121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.268 PTPA-like
[ 703] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----773---1-112-111111111111111111111111111111--11111311111111---------------------------12-112--------1-1-5327344341522345355254CY7143633434346235334432455146222455113112545B----------3325134--5345- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.41 Domain of poly(ADP-ribose) polymerase
[ 704] 1111211111111111111111111111111111111111111111111111111111111---1111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------1-22-1---1---------------------------------------------------------------------------------------------------1---------------------------------------------------------11-1----------------1--1-----1--------------------1-----------------------1111-1-----------------------------------------11111--1111-1--1-------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------- 2112--3-622122211111111112-111111111111111111111-1111111111111111111-111111111111111111111311111111114-1111232-211112121111132132552-323112121212112111111-121113111111111311114232N22222355213622-1-12 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.12 DNA topoisomerase IV, alpha subunit
[ 705] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111----------111111111111111-----11-1111111111111111111111111111111111111111111111111111111111111111111111111----------------------1--------1-------------------------111111111111111111111111111111111-11111------12111111111111111-1111111111111111111111111111111111111111111111111111-1111111111111111-----11111111-111111111111111111111111111111111111111111111111111111111-111111111111111111111111--1--------------------------------------------------------- -1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.128 DNA polymerase III chi subunit
[ 706] 11111111111111--11111111-11111111111111111111-111111121111111--11-11 --------------------------------------------------------------------------------------------------------1----------------------------------------1-------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------1------------11-------------------------------------------------------------11-1----1-1--11111111111111111-1---11-1------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--------------------------------------------111-1--1-1----------------------1111111111-------------------------------------------------------------------------- 1111111-1--111111111111111111111111111111111111111111111111111111111-111111111111111111111121111-111111-111-11213-111111111111111271-2131-1111111111111-1111111---111-11114111111-1221-1-1121132--1-111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.137 Rof/RNase P subunit-like
[ 707] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----11------2---112----211---------1----1---1--------1--------------1----------------1---381131L-----1-2-4-314533237D434642427966Cj--62946645823434958374-63241516131252-3122------------125412-------1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.66 Transducin (alpha subunit), insertion domain
[ 708] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2111222-2---1131221222212122211-12222533344222112121-111211111111----1--111------111-111112122111111--1212-13143535322332272671416Q3-427212232253331333224175222223221222133342-12161111141242211111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.188 PWI domain
[ 709] 11--11111111111111111---1--11111----------------------11111111111-11 111-------------------------------------------------------------------------------1--1------------------1--1---------------------------11111---11-------------------------------------11-111---------------------------------------------------------------------------------------------------------------------------------------1---------------------1-----1--------------------2-1---------211111111111111111111112-32123221111-32221132113311---1111111212222222222---1211-------------------------------1--------------------------------3232-1222221111112111111---1--------111111-111---1-11111-1-1------1111-111------------------------------1----1-------------------------111--------------------------------------------11------------------------------------------------------------1---------------------------11111111111121----------------1----------------------------111-11------------------------------------1111111111---- ------1-------------------------------------------------------------------------------------------------------111111421111113-261BC1-425121211111-11211--21111111-1311111132121-----------------11----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.118 GckA/TtuD-like
[ 710] -------------------------------------------------------------------- ----2-----------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-------1----------1-1------------------------------------------------------------------------------------------------------------------------------------------------------------------11111-------------------------------------------------------------------------------------------------------------------------------------------------- ----52--------23333-----1--11--11111111111111122121111112--111-1-------------------------44335B22223591556--3--------------------------------------------------------------96---1--------7bLw3QI--CACE- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1- * b.25 Osmotin, thaumatin-like protein
[ 711] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111111-1---11111111111111111111111-11111111111111111111111111111111-1111111111111111111112111111111111211111154846713212243533328H3-2352334A234223231B2132323225-22111733843111111J11111512413311-112- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.245 EB1 dimerisation domain-like
[ 712] 11111111111111111111111111111111111111111111111111111111111111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 111122116221112111111111111111111111111121111111111111111111111-1111--1-111-2---1111-1222111111111111113341111223221211--121291822I2-22911-111112-11--22121311113131121211111111111L1111182361421111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.94 Ribosomal protein L19 (L19e)
[ 713] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----441-----22222211222222222121222222122222122222212212222221211----11-111---11-111112222322222122223255712-424633223332332343514N315452332533532333332262232413411111---61122------------1-2--------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.332 RGC domain-like
[ 714] 113334----------474553342-----34---11111111-11111-313-5564457-326--- -------------------------------------------------------------------------------122-----------------------------------------------------21121---11----------------------------------------43---------------------------------------------------------------------------------------------------------------------------------------1321-1111111-1--------------5--1211-2A2-54311-14---3---------------------------------------------------------------------------------------2-1-------------------------------------------------------------------------11-11-1-1----1----------------21--6B41472163222-596143553------64---------------------2-----------------111---1---1--1-11-----1--------1-1----1111111111-111111-11111111111--------1-----------------11-1-11-----------------------------------------------------------------------------------------------------------------------------------------------------------------11---2------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.152 Aldehyde ferredoxin oxidoreductase, N-terminal domain
[ 715] 11111111111111111111111111111111111111111111111111111111111111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111111-3112222222222222222222222222221222222222222222122222222221221222212222222222222222222322222222221113222111111-11111112--1441-111-11111111-11121111-1--1111111-111111111211171111111222121111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.235 FYSH domain
[ 716] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------48B9C777775565AA482CM9-78B4654736783545264485A86634138-23414423-------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.228 GDNF receptor-like
[ 717] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------D78795743-546589465EQ8-76D3434725A63333-141938366411354536522BHC3------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.62 Cysteine-rich DNA binding domain, (DM domain)
[ 718] 114334----------474553342-----34---11111111-11111-313-5565457-326--- -------------------------------------------------------------------------------122-----------------------------------------------------21121---11------------------