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Summary of SCOP_FAMILY&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbspGo To Summary with VIRUS
see 1-100     see 101-200   see 201-300   see 301-400   see 401-500   
see 501-600   see 601-700   see 701-800   see 801-900   see 901-1000  
see 1001-1100 see 1101-1200 see 1201-1300 see 1301-1400 see 1401-1500 
see 1501-1600 see 1601-1700 see 1701-1800 see 1801-1900 see 1901-2000 
see 2001-2100 see 2101-2200 see 2201-2300 see 2301-2400 see 2401-2500 
see 2501-2600 see 2601-2700 see 2701-2800 see 2801-2900 see 2901-3000 
see 3001-3100 see 3101-3200 see 3201-3300 see 3301-3400 see 3401-3500 
see 3501-3600 see 3601-3700 see 3701-3800 see 3801-3806 

       aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
       ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
       eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
       rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
       01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
===================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================================
[   1] kkeJjcfbpppmmjuq*Wrjrmpm*gk**t*oVOPNSQUTWUQmxmn*Xi***IergenXgUVNp6IL ou*h***********y*qr-q*RR**qppqpl********q**********x***ty*RR*******************l***LJMHLzssqDmXZW24Vtegc*l*orIKKKKKKNLMJJMJejkkjthetxul*****UTV*x*******z*sulefdje**v*****YkbbYXWkVaVZ***pq**Oz********************************************************************h*****mk***piz**************************zyyy*z*****xz*****************************v***********sX****q***jw****i***f*yssjUZXVY*y****s*****************1**********wM**************bjg**********yvyyyyyy***lq***AABCFDDD9AGJKKQPEMNKLHNMHDBFCSYeiYW*********************************Na*****************isYj**RWUSWUUtpo******h*v**r*****Sxyxx***w*******s*hVWXQYXYaZSSNNNMOMLQWhNRaji***t*t*axq*nw***lw**ywzv******8-Wp*rn631555*****************-***************************************************wA************66VXQWPPSfiihoc*******yzZksghsnv*jknroYpZll*******************VQROQVTQQc****************xrqsspqoXWWWHExvooffeeLKIKLLKO*TwKHJET-UPSSaTNiheQUgPZXKKK***ts*****R*mV VTWb***2**hp*****************vzy******y*v**wxy*****************nudkdFsmftvtwyI*xwsrm**ejf**z*********s****R*************z***********B************z***z**n**********************q*********************** * c.37.1.12 ABC transporter ATPase domain-like
[   2] BACIFBJHKJKHNKQINGGFHCEGSPVMYVpSMPJKJAENJIIMONQT8QXSYDMNOHIFKACEK7YF aPeMskbjtuimVobUbfg-fuNNhqdeedfWqws*zxywQyo*ukpcchhZoshgXeJJym*nxku***fZRVVcYWLOgdID9NJNmhk*IdVVS11QgYVTqdgWbPMMMMMMLLLLLLLWOVUZfVYVvKVXabWlJDHiN*kjlXcaQRRRWWXVWVgULdyrwgMVSPMMMTPOPMcZUIIFEIfglllllmjqjhmmnknkhbmmejhjgmhifhgdjdedhejsVSRSSSTOUTSSSTTSRUUQfWWhZacdbYabZbYeYZhiRVPTSTVXXQUXWRQVYWVcXVUaSVUTTYYUVUTUZTSTSaZVXSZXaTSqcdpnmndklickYikWWdWcbUZcUQjVfcYojvjYgQYPXQNPUDUOaRyUPSTJRJHkUXgYcrXXYUYWdNNKNMLNMKLQ-olhh*ghhTSXJWUUVSeSYfMSWQrTXTZPZVQddYPPcaccccccZYXZZRYaDDDBCCCC988mEGDGGEHHEEEEFAAEF9SbcVMUVTSlaacgbcfVVWWgdkkbXgZQiZ*odbegJPjbUghpiUsyZimwXZwYZPVXXQQMLLNPXYQwYgbg*nZQdoPibQOVGZafdZaoZvjfne**keSIJJKJHMIHLMNLMNMRJLVKHOUgbhopn*dtXliuh****kru*rsvmsum*ruA-TgYTaADBDDDbghkgegfprhffegnd-oicgojdefiodiZcfccikfjfefkhcdZadacbjbbgjbZacfcfhachXAabbcddcaddeh99SPJKLILcXWVjgydhdXXWWUQTRRMXSYUVUUPXRRSXUkffrxhkmmqnnjljysfqTQPQOVQPQUlnpxkmmqmmnrntfhdiikgeeecdZdIH*PaaYYXYIJJIJJIHULQ988AF-B689E88456BBCAG7AABUKMPOIGJJIKdQP *******C************************************************************d********r****************************g*************************Z****************************************************************** * c.37.1.19 Tandem AAA-ATPase domain
[   3] 656646FIMKMILKKG5K8A8895eMORSQSO7B743B16332BD6CG7AIFF5A9746BCCJG91AH lq*K*KEVUUbHLF*****-**VV****************N*v***gXE*nJ*x*THu54***D*v****a988887A66JH*BDHFCebgY5cED4--M*Pme*c*es32222224332222HZUSVddSVfaWnoowz785*O*rs*oomIINMVTQaSVPbSx***iTOPQSTSTXQLUfYRLLHG8SI*ccgbgohjZnohprijallmrimtHQOpdqiKJJLLI**KNNNNNMMNMNNNNLWKLVRL9O6QWBHA68bjFFNLOMLGKLMQPDDDCDBDDGGDEEBEBCDCAC79B99B9A99989FCBCB7BBBIAC8TSFFFCFEGGEHqAKK7FIBO8D43ME8C9KJNGDH899867BA8JClJz*ru*65556*i***VQS*****Zegfaafbfey-***********8**************p*dv***qz*ljoYYYYYYYY*zzeZpug67566666552356785695557456576So**uLd**m********************h********GSz**nZmca*u*t**SccVQPPgPBBGDCDALMUklZT*ZiNCROKRMMLNFbedXYKiMRuyxz**ITCGID9EDDBH99GAAAABAAHAHAJRSgcSZkdfPlUZRZWWaVbYXSTQbYXXSdc2-6NPNP222222ZdlrQiSWcceYcbaaW-caZbbaZYaWcbaVXWZXYu*tpWYURWQUVVVWUVVSWUWVPvYYSXWWWJ3XWYYabaWaZbZ339GILIJJZaccNa*khA99KBM89978NCDDqnksqQiMUQtY********vuq**r***TEHFCGGDEHRROjKKLLKWYVRYjlqmsljSVWOHHH85SIjjaZfe11111111A1A----4-1-322-11--2631-----999FBAC9B8IxHS 87CD***-*aW9Xi************************************************shxTVaLjSZ*e*aUQWVclmkwtSdb************x****4*************************2******r*****j*z*k*wu**********************y*********************** * c.2.1.2 Tyrosine-dependent oxidoreductases
[   4] HHEADGECHMMLJHMDKTPMOLIOVKMQNLWIAAAAAFNKNLHGLEFOABeNU7CEDFA8DJHBC18D JKVG*RRWcdfFMHmRUNM-NiJJW*NNNNMNrnsor***KzU****NXmbN***KNz44kaeQ*g****aTOOOlZVFGdXcACEBDCCGC5F452113H87AOEBEGAAAAAAACCDDDDD8DA9DEBCVCLBgnnsrABDpbpmnpcbgPWRRKIIMMLRhGk*n*a9HBAAACKA9BAvhVWVac5YKjz****z**fx***y***rnms*x*NRexrbWfabcab**HQQRQRQPRSPPQQSTQPOWjeSWcgVMOLPjjJJjeGMLMWOTTXTUUVQOPNSSSWVWYWWTUSUNNOOMOPQPPNNNUSPVSQNNNTXyYi*cdbcdjdUZVdkddLTUP*PNTFnUhIG**YcJPXZKHQOPbCPTIFLkPPS9DA8Gzs***VR***v*u*******w***1**********b9**************WNL**********aXaaaaaakpoTbpc*55444554555454553554444433353GFazMG*********************************FW**************w**MWSV*tJLIIIIJGINj***s*Ukju*Un*qn*BeaXuOXcXVccVip*HjMMMIJMMMNKGBGCB9AAAAIaMFLVR***p***V*i******s*************7-HKYJm322333****y************-************************oz*************************Z2************55CQ69869TUSSNT***dddrYnIQUOPYRUg*****d*Ujd*t*****************EAD88ED8AS****************notolWYVICDD44rpIIDCFEABBAB999N8I89G76-1352435222242943333PbaQNXyVaWKZC5 732389O-G4648MH9DJCOBBBGNF897C9BBE96B9AC9ABB79FDFMMAOACBFJ8C7B8879AA58A6A8897BG9A887AA7788HEDCAG76895MBEI91Oir*******fUZWemc**Y*W***7***bjdX*UotcLgTYP*SS*W*kv*LRRi***i*o**Vk*bBfjC*BEDOJ*YY*DjJGIlgRdK * c.94.1.1 Phosphate binding protein-like
[   5] ---32-4533334437-122122-1--8-1-11----11111-3---5-------1141--1--2--- 38u1f22111142213445-5611D55555565757B6WM1oSs34624324558413116472MDDQUUL444445521272-11-1-----1--4---1---31-11222222221223324--1---1----988GJ---S-sJRMGDI9955-1-11187BEohoY-1-----1----65744--1122---111--111111-2-2211---11-1---12112133-22121111122211--1--1-22--2----22--1-------11----21111--422211321111111111111111---111---11221----111211-1-1111111-2---141--1-1---1--------3J-c1---------4311---31211------------1111-3-1-2-----211-211--1--5--314231--122222222-1---411-------------------------------1----11-223323312222112123221431342411-1127563345235221732412-----------48617343132-1-111----1----1EBEE**13-------------1----11---11--1233277-424121113332223-221144------2-------1--1-1--1-----2--1-------111-1-----1--1----------------2-2--1---------211111-11-1----4-121-411211F12111---1----1---------11325533453444532224433---------13232-----32432-12-4--111----115---2222---------------1-1111111---1121--111-1---------45- *tx****6************************************************************f********y****************************O*************************t******************************************u*********************** * d.144.1.8 Choline kinase
[   6] ----1-1222222222--1----1-----J3--------1-----1---64-11-1132-11-1--6* 6791J------1---------1--1-------1---112--529485-4423698-1---7A213-18EA33-22411--21---3-2DFOD1B33---3I559TAUCK--------------4--1------G-6AA74224E3-1--1111------------11137------------232--24-1516666655866B57D759561276D252632-6775849m--------------------12-11-1-121----111-----132------11---------------------1--------------B22441111111-12K143-BA44-S-142I8-ABA-234-12111D---321222-----------------------------1------E------1--4------4-11111--1-1--3-1--------------1--------------------------------------1--222132-222222112522251-11211---25D---121--1-121----------1-21-----FU342----22-1--FbJEC5k1565D7I5983--3344444443444344434233--1--38I2233822132311313714-4639---2-12-------33311--JH6-62A-3-L2-8269488J88222323111122-4-1---3-42--26--5-44-4244--555355555445---2---------1-K--2-22-------2---1111--12--1K337123-21-112-725111111-11--1-14444411-12462333512--------2AA6578-1-11111221------------------------19A224-5----L2D 1--145e-xPU177E3453B4A5A6552232228873232322434234557745567478743421222223222222232232311153441231-1-313311-vt8*****************************************************************-EG3P356WEOeXm3UU1KV*g*m * b.1.2.1 Fibronectin type III
[   7] 998AA988777787A7G8ECCEF9BBCBCCAC88DFDCDBDDDCB9FHAGHHEFCCDCDBB666D487 JIJCfHFDFEDIG9HDEKM-JKDDKJKKKKKHHNONSNPSDLIPHOGLMFEJMMJEGI88KLKDPRTcYNOAGIIAA9HBJHDGCEGDHHJHAHIJK34GIDIEJFHEEABBBBBB7797777DFFKHJJGJKQJLJIOUBBCOCgYPVRSSJNKKFIIKIGJSILaYbUCFFDEEFFDEDDKMLGFDEEHFHLLMMMLLQKNLLMLMLIGHFGROMHHJQKGNIIIIIHKNKMKHIHIIIIKKLIHHJIGHFDGDFGDFFCFNOJJFFGCFEGCGEFFEEFFFFGGFEEEFFGEGFEGEDEEDEEEEJECEEIIFFGIGHDILLKQKLKLMMORLQHPQQOJLJNNLIGIHIMKMLOUMHHGGEKIJGDFHGDLLFGIEEDCDHFJMIHGJLIIJKIJHJIIIIIHH3JJJLKIHJKMGADHHIFGIGIFIHGICEDDLGKMMLGFPGGGGGGGGEGGHEIKKCCBCD99999AAAAAA8A9A99A988A9A8EFGCBJJJHJEEFIFEJEDEEGGLOFFFFEEHOKKQNLCFLJKLKJLINOMOKIIGUMILJMIHHJMIHIHGDILJKNOKNIJMHMPKJLFMLNMKLNORMPNMQeGPGEDDDEEFEEFEHHJHHDDIGJBCGGHJKHJKKJHLLLLJJKJGINIIHLKHMMILH84FFIJGBBABBBJJHLJKFKLOMKKMJLJ-LIKJLLLIKLLKMIIKIILONKJHKJHKIIIHIIIHHJJIJIIFHHGKKIKE7IHIHIIIGHJKI7BEDDDDDEKIJIJHNGLFDFIFHGFFEDGFGHGGGHFIHFGJMJLMRMLJJGKIKHHIIGGCDCCCDCCDIIIHPIHIIHHJLOLGKLIIJJHHGFFFFEERBDEDGFF977C8BCBFAE9C9CC-CBACCD999DBBEAABBBCEKFFGHIFIGBEDG *wbe***4***h********************************************************p********v****************************Y*************************K****************************************************************** * c.37.1.8 G proteins
[   8] -------2----------1---------------------------15--1-----------1----- -14-------------------------------------------1-------------1---112--------------1------55341422---1221-322-5--------------122123222322222-------D667553443344434333349955333332233332-----22--------------------------1-----1--------------------------------1---------------------------111----------------------------------------112222222-1-2-11----1-1--5-121-1211---11---------1----1-----------------------------------------------------------------------------------1-------------------------------1--11------1----------12-----1-11-4-2--1--21333343122--2-------------------41---232343333-111111211--1--7-21111-------111111111--11--12213-12-2221111111111111111111--121-------------------------------------------------------------------------111------------------122222-1112-2-1---------------1111111----------------1-------1-1--1--24221111122211------1-----------444433--------12------------------------------------2111 *******7***P********************************************************l********m****************************W*************************q******************************************k*********************** * d.58.7.1 Canonical RBD
[   9] ONGEEHSSPPPOPMVXFSfSNPQFgZaWXPYOGDKNTECBEBDKMKLgKJaXWCXPQcOKKCAEIABE ONhN*IIHOPKHFHMPRPP1OcIIUiPPNPOKlghicYgoKybwULHDHIHGSPTGMEAAdaQEvSyqzzVEHGGOIHEGFQNGFNGKRRTLBVFGL33KJHHFVFQMGCDCDDCDDCEDDDCIJELLUIGJXOIidcisHGH*I*j*nZcpLMJIMJNILIRbKa****IHKJIKJHJIIJQOOHLFFDYSKOOOOOMWPNOQNQUNLHLLKMNONWTMQLGJIHHHIIUKKKIKJIHHJKKKKLJIIHLJOJIGINFIGGJLMHGNPJRJIOGIILJJLIFIHGHHFIGFFJHGHFGGIMKJGHKLGIHGMHIGGGHHHHSSRXVKLKKJOKNPMQNRRSLILORSIKUPeYPgbdVbOPMQRPRGMFDFOOXKHHTGGIGLLUckpWNNTUXPcKLJKLMKLLKQ-QaaOacTYWXQEWSTPSQdQQVUQNPMKJRSaUYWTTOPKKKKKKKKULKHKVYRFFGEEEEEGEAACDFGEDIEBBBBDDCEI8ORQRHKOLHWcabSaZdUaaZaUjifehiTecbabddmFGWXTbaTYOTjgbWSNUyTQKONPGFGGGFGQSOZTSKeoaJLSVLYPXZbGVSUQZWYYocZcZz*RYIHEGHHJJGIFHHGFEGFFGJLFIKWURRPQcRRMRJQKOQRONTPPPNPJQPONSTA1HSVRO888888IOKOOIOKONKKQPPPO-NKIMMLMOKSNPLJJKKKOONRJOPQNJQKLOLILLMNOLMKLQJGFJJKRH6LdccWccVcYXV77FHLPLKQKIJKVNlPRHFEHIKGHEEEGFGDRNRPRLJHQIXOadidXZfjZeZfaaXTUCDEBEDDFDMNNQSMPLPPUVPUULKJENGEMNPLFGGDFQJOPJKONEFFFDFEDHFDCGC9B-BBA8E97777BBG77788AIQHRQKIJLMHNGF pvUe***B***w*****************************************************zvzcy*t**vwxTuxy*x****uw*******ttvwr*y***U*************y***********J******x*********s************************************************* * c.37.1.20 Extended AAA-ATPase domain
[  10] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------1--1----------------------------------------1----------------------------------------------------------1---------------------21-----------------------------------------------------------------------------------------------------1----1-----------------------------------------------------------------------------------11--------------------------------1------1-----------------------------------1---------------------------------------1---------------------------------------------------1----------2--------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------1--1----1--------------------------------------------------11------------------------------------------------------ ----2-1-1-----B-12-212-11-2--2222214-------1--11-21133123111-1----------------11---1-----1--11--1-1---11---2-1**********************3*********************************z********----------1--412----4321 * f.13.1.2 Rhodopsin-like
[  11] ---9-----11111----211-3-2--112-1-11-11-----33-31-2465----21-----1-d- -7G-B1--111---2------2--2-------1---111--V8N22-----------3--212-8-25331-------1----1-3141114-1------31--45423--------------5311241112914332912242M9H878911112-211-361CLFLC121211131211265-12--1-1-----------------112--------1--------33-------------------------------------------------------1-----------------------------------11--111-----1---------2-3--1-3-----21--4-111122-15-K1121-11-1312411111-11-11111111111-242532-122--2111213121511211341-11--12211111111211111-3--------------11-------------31-----32--------11111---1-1---12---5-------41-11--1-3211A-1--21-----------2224-4--1--21------242111234-36J-3133222222-1-1-------44113--1---11221--6212353134233213256---2241---------3-2---------1---1-1---1-----11-112-1-4425-------------------1----1---1-1111115111--2-----------4-11--11----------1-----1114-211-112-1---1-22--1l111--1l-1222222122-1231111-12---------3133--111111111113--------------------------71-3---321-612 **uy***A************************************************************v********z****************************X*************************m****************************************************************** * b.69.4.1 WD40-repeat
[  12] --------11-1-------------11-----------------1-1---1-1-1-----------11 -21-------1--------------------------------1----1--1------------1----1------------------111--1------2-1-2B1--------------------------3---------1--1------------------------------------1---------11111------1--------------------------3-----------------------------------------------1------------------------------------------------------------------1----1-7-111-------------------------------------------------------------------------1---1------------------------1---------------------------------------111----------------------------1----11--------------------------------1--1--------------------13-11--1-1-------------------------------------2-11----11-------1-------------1------1561111211-311112411151111111------------1-21-11-1-11--22-111------------------------------1------1----------------------------------1---1-------------------11-------------------1------------------------------------------------------R-1 ------2-----111-----11--1-1-------1---------------1-1------1---1---1-----1-------1-1-------------------1-1--11**********************q*****************************************p-211-1----2-1----------- * b.1.1.4 I set domains
[  13] -----------------------Bh87K5Q9I--A31133333*l1B*5IMEJ-2-2122-------9 e**E*CBEDDE969KIIDD-DY55KWDDDDDGdQRTWbdbQta*fZIDIPMINQQDBH22WYrD*Pj***RE999KB96BTDN37AAAec*k-g663--A*GfY*a*T*1222122111----2FB3IKAAHInF*****UHR*J******UacQS88AFDAu*Ys***l696665685655oWRDD697JPYllololnqRpkppoofncZTapruLTTvKPOIGFHGJ**EHHGHGGEEFHHHGGDGGGBK8A6HH77549DD9AGF8997A6797KMLHFFHGEFEEEDEEFEEEECDCCCDDDEEDCCFCCAA7BACCQzYg*iiinknnaiUdphhMMOJ*ThBDYakaH**vXPRFOIIGBMW77A*Z*****CCCCDgp***jWc*****PPNOOPONONc-********h*k6z************ozUqaUbxuuvaiVLLLLLLLLKUUMN***55555566446A444444644442444445Lc*NEUVSKa*******mmld****zxz*T********69****y*gf*****Oi*yffdY*Y4555646JIbq**p***iS**P*****9*******n*******b*kGIG9AAAAABAAAAAAAAAsuMLeCC*pM****X**b*u***ots***nw*u*q**--9UTbY------eXYXTZQYbaaYYYaXZ-bbYXbXZXXYbZZVXYWWTabbTYQNOdZbebfdcbcccdcefiWURWUWYH1bVVVXVUVWXVV--BRCDCCCGGFFLh*R*66664636556546BKKIJLDKHLGi******************421213212Tjkm*vxxxx***************QPMP23*E**bdnm66677676D33-------------------------GH8EEABBAA8*4Q -1--RR2-321-11hLMOKIFFHHDFEAA564677898787996A8KLDFLLGPFGECCEEE876434284685645154477796866AD7MAE7CACACACHHP1HKV-------1-1-----2--------------21----31---1-21-1-D11127-3--1-7-2F13EFDyA9A96*Xe*PqZFAf5767 * c.23.1.1 CheY-related
[  14] ----1-244434454311-1---111111--171469457879RD9C*4CWUS-24342--237--7B Y**1d12322222184633-3344853333379555449A5GAM4A35413-6592-2--C741I4ENHO911112224222486HBCPQVQ3PMME--CPFGQjZVKK77555577767777FEALEUECGSTGQRSdj111s3*QmdffoLQHGAB76B9RJJioi**5J4J656e5G96EC57798I688CBCADDCC9G9DDB9894487BEF8979757655656FB5444444444444444444412223223221221125213121122211111111111111211111111111111111111111111115C3KB555465496573676475B7D1194757979D748375122428IfG*OKLO45244KDlciIGGIENIM78797779889-DESCEbECChK5OEERTOUcaNSSHFPJVJLCBE9DHGE99999999FEF6CdJW44334223127F42CE13A36344232322BNQGC6CAABQFFEJLLACCBEDSZIGGDEGUORJGKL9IFEHOADD8H9HKG9DJZNFLPJ76867766F8MAEQU*foPObTJotQRTEnandXZcRTmr*n**PT244425544663523323333B479HGJG9TRaXEZHFGEDEBMGEBDGBCFGJBJO--7KGCJ111111DAAF9D8DGIEDDDEEB-FDEEECCCGEGCEBBDCBDDCDEF78AFGEDGFFFFGIIFHFEG96A975791ADDDEDCDDEDF--5F7B879A9C9IBfAB98665544343522BA999968575CREEFIKFLJDHIDFEFEB2333333337ELMKDEEEEIONKJMKJFJFHGGIACBC--jvbaccijIHIHFHFEYP-----------1--------------9563476859IqFB NORc***2***g***mt*yyw******uvwskn**wqxlurnswvtnskp****es**kxptlceYdcGgZekadbeRbhcfcoeeljkq**t*u*slpoo*l***B*************************a******************************************d*************y********* * a.118.8.1 Tetratricopeptide repeat (TPR)
[  15] -------------3--2-12---11--------1---1-------------11---------11--1- 14M-1113444--11----------1------13232231-1--3311--1323211-------13-2351----------4---6--2--1----*---61-46-523--------------5--1-1--------------2-D323--22211--1--121144324------------312----621-4444433415123321-----454---4-31----1-53----------------1---1----------11--------------------1--------------------------2----------1-23-------1-22-11----1-2----1--------11-------32A-92111-----121411-2---------------1-11111112-11-4113--213-2131-13-12-----112222222212222312558ABAAA56em66UT46S543A82Q8d*111411322211455515111122231111116h83333-12351323334322133523442-11211112212376429--2---211--2171624-1----812462223222322-D-1-----1--2111----41--12-2512-233-3--2422125--1-121-------2-51122441211131-512221-1215131111121113312-1----1----------22322--21-111111111111--1-7OG9BKQHK5181---------------13443341---1144342614132222223111-14211--1111111111-2184595C93334332-19*GGA6FD22212221851-----1------------------------------33- JEJN***-*dd*qZwbu*p**********twmw*****z*y**yrs************c***MLJJIHAKMOKHIKMELKKIJIJKGFHNplu*Y*GKJHHGIei*2*************************v******************************************D*****y**n************** * d.211.1.1 Ankyrin repeat
[  16] MMH5LFD8OQNPMMOEbENNNKCChKMcPJWG88464ACCDB7ACECJ87dRJ4KPMPI9GHF9F-65 788B*KKOPQY7M9UMOKK-KYAAO*KKKKKLhilkVt**JlLl***Nm*wN***GLu44fbeZ*e****aYSTT*gbGCKCX55556555537224---12-1652A26666666777777797758876C7C7gonrp777ojOPPUNNORYLMECCBEANMIJcWUI7D87756E7875xmQRUrt2XMUiililkrsYhkmkgm**jjcfijoSTmtqUTZZbaZY**JQQQPQQOQSQQQQPMOMKKaQNMVZKDJLLSTDDWTFGEMOQJRVUWUYSSTMQQXbbadaZaXXYPNNNMPPPPNNNNRTRONIRRRQdpOZvVYUUWcWNUNgVRRBPOM*IMXIyHgD7utOOBEuS9FUSSmBQOA67DDDCEBDABRM***FGazef*W*******w***-cb*YW*Z***GA**************377w*********GFGGGGGGQNPBHLIs55453333331111221111111114456I37BC6r**********vk**t********i****wj*p3CljkmTgUXve****QZO8KCElQCDBBBABDB9FNDHJ*9TTacIGeWWeDHG88DDHFACBCCNY9PABCE5FEFHCB7A99A98996H86977ifmBW9E8D9vAFEFF7DGFFEFCIGDFHC5-5EFCA------****W*squuosooorq-trrrqrqtnrtoopqpqpo*****QQallkimllklklklkjl*eiejjilP1v***********22C787878ABBBC9up*TTTNPPFJLEESGIQPPPNQ9MENMgL*upv****p**x*X***955559655BaggnjijiilotsqA9FCCCCBCC9999125K66666588887888L7SE9H6C-F9EAEA87787E78GC555U*ufam*knj7G9- 1-12111-1-2-151112-1--111-1111212212-222-11-1-131-1-1-1-121221--2---111-3--1--1123312112-33-1233231-14221---12811451-1--223222-424N2-21712-----1-111--12-3-2-3E-112E2232-2H2363424--11-13D13D1--1-71261 * f.58.1.1 MetI-like
[  17] 66B8B7HFDEFEEDFB8AEC99ECSGHQJJME4A877BC7B98497845BIHDC9AAB8DDBA9E176 OWgH*C6EKKLDEF*mlRR-Rq33**RRRRRc*****t**AqeoULGB9KJ8dekLFS11ornD*e***vN2222444-3C7Z994545451-6332-13NGHHzGXIM222222223122224EF8EGE99DFGVPQRR453UTlVdeTTRKPMNJIRUNNJMFVfYnZINJGIIIPLFEIKGOAA763DGBIKKLMKJP9LPKJNPCCFCHFMJPC8BIDML7AA689RQ8CCDCDDDEDEECDDDFBCA783-22-234169333433257-223444333454354433343443133322223222453333353343K59GCCCCCDCGCB575559D7DAB6-632FBJHMJA55BAD9963454HAWqMMO7A768IV***VKNcScgbMRSWONVLPWq-YXyYb*Yvl*W3*vwvsu******nhAJDWsvdaWdtj*IIIIIIIIONODIBOM44453445323223332213232442414OCh*I9SmYKc******kYYYW****iikkLi***d*th3BhckUMSKGbcwYryPJJAC8DYDCDEDEAD99DFXELVWCA9A65DD44A4996685576BCFBpyBG853524447243633333334-42AFGGFBHPRcETMJJSSPSMMPKJINOHOOMQa214CDFF--1---EGEJ6BNIHHHIGIGHI-IIGGJGEHJHIHHHHFHHMSWUFGNOCKDGGHJIJJIFGJGGJXC9BCCDC64HBABBBBABCBA345G7B797HGIIBSOUg66659575673878CRQQTQDUFMGQQonmrrzz*Ww*qnXddhB9BA99999HBDGKBAABAPKFJKNNQMTMMFGG45655583OO9ALM23311322515-1--4-2164113111242421221A3465766669F37 GFEFwqX1kKH4MJg************w*p*st**yu******rkl****************GGMBKDALF7MSUJF8FELJKKROGKG*******vcsYkqwnik5P*u*z*u*yxcbaXclh**W*X***8*t*YVTXwYiqmPhZXUqRP*Zxef****g*o******ZZ*nSz*r*imbyw*********tnru* * c.3.1.2 FAD-linked reductases, N-terminal domain
[  18] AAAAA9AABBBBBBBBAA99999BGDDHHJGGDCA999AAAAACC9ABBBFIFBCDCDDCCB9A97AC QTYEQFGGGGGFHHGGGEE-EJFFHGEEEEEIIIIIOIMMGLKNJGGEFFFHHIHHFGFFLMHELHMPRRGCEFFFFFECIHIKIJIKQQSNGPLLI9AHLINKNPQRQIJJJJJJKKKJJJJOKKLLLJJINKKPRROPBBANCJJIIKKJIIHHIHIFGFIIFINLKJGGHGGHGHFGHGLKJKKFFHLONUVUVVTVWTVVVTVTOMOONNUUXOLMPNQNQOOOOOQTKNNNONNONNNNNNKOOQPOQKLMPPMMNLOPPLLOPPNOLKCQTVMLLMNMLJKKKLLKKKLKKLJLLKLLLKKKLLKLKJJLLLJJJNMPOOQUUUSSTSOTLMORSPMMMTJLJOKKNHHKLNQKIOKJKKKJNIKJHLWONOTNKKKLVTXRTaOPQRPQQMMMOMMNOMNQ5QQNSQQQQQYNGSQQQSRQUUSUTOOOOLMMTSSRQOMMMMMMMMMMLKKJLNOQGGFFFFFFFEEEGGFFHGGGGGGBGGEFGFLNPKLRRRQQSUUUTTSRQQPQPQUSSSRRRTRTSVVdHNUTSNPOLLNNNLIKNNOPTJONNLLLKMLLMNPPQQQNYPVIRNMNQQQOGVVVQUTXUURRRRWTMOIFFGFFEEFGGEEEEEEEDEHEEFHKKTTRPXYTNWYcQTRTRRQQQPQNPSRSPTTL5MMMLNKJGNNNWSUTVbUbYYbbYYRZZ-YacYYYYbbYYbbXYZZYZXWYXWVXYYVZZXXZWWUZWZYZZeYYWYYYYRGbXVaaYXUZYaaGFQMJJJJJRRRPPTaTVQQROPPQQQHONOMQNONOOMPNOORTSRUSRQQSRRQQSSQQQMMMKLMMMMOVVVYSTSSTTXVYXMNPPPPPQQSXUMZKLMGJJILHFDCCDCDDDGGG9A99B-ABBAC89999AA9AAABAALPLKLNNGMNFKJN RM7HURW8*PTEaafXWWXWYWYYYVdbbWbWbWWZXbWaTZaZYWUVcidcgcbeeWXbXbWQVTVRFQUOUXVRWGQTQTWTPUhgfSjSWUUWVVUSRUSqmm9U*M***y***hf*wh*o**Z*d***M***atgr*lw**dzqgk*kk*j*rote**i*kpTxdn*bcvbbdfk*pzofv****Y**cbuosor * b.40.4.5 Cold shock DNA-binding domain-like
[  19] 332-31LIKIOKKJOI5B57333A3123532521421-24421BC7252-331-3432542MGH5--- CDU8*A8ORSX8IGGDDCC-CH22RqCBCCCFLDEDZ***7UGdMKEB6HG5ebZB8L-1LKEERI*lrl5D455HDA34I5H26424FFD529--1--4E273P5D3M11111111111111223222-112236CC89432682142123112213-2231--31253-1----12----86533436N6WTTUTVQTaJWSUOQTE4YWFaRUP9BFHF97BDECE9RaBB99B9A89A99A99KGGDG78E7KP8F76AKKCEPP99HHDGBA97773423377333333333336766866667766211111211514-EM888988877778II4665331217-141QM89915B6C22122-1522XBBS26957R8vRW84DKLJICCFFDDDGDGDQ-GHkGDxLi8S9-cHJJJNEYXTJMbHB9817K6355434PKPPPPPPFSTC962D112432212232678745A963665617315Hc9AKKDFV******vkijc****stsqSk***f*og-AngZ36I99S6F8aGDO72144J9333444323145B57947-42668234-645966A326876AB4A52251756744-11221211-221388C8I66AA3E885DDGH9BBCCB73A747A82-1---211---1fWdQDhSaddfabfdba-daYafceZaYbdcccaccW***UVKMKnddgifkkljhbmcgf*QOJbYVU91SMMMKNLLKKKI--31AC8CAPPLM216BE866997167363228YYYVXDS695V5beYZTjikAiqqh9UWcPEKEHPMHE1566E9999999867BCIJIJJCCC42221112554443---1-1111-1--------21---111-1--1----13121413334A25 3567PIE-RFF9ELO************************************************p*Xx*X*bc*g*huS*xu*wz**cgm************V****1EfJ******gSLSKWkV**HuR**o2xp*PTRIwNfrfMZTRMkJH*Nlein***X***q*v*****q7OJ8*GJGGXjp****fLLilvyF * f.38.1.1 Glycerol-3-phosphate transporter
[  20] AA6456778777887A89B89958NGGQGLHF68634279795BABFD59SYP59A89B89BCA6138 BXcA*DEJKKJACCUJIIK-IM77UVIIIIHONNMNhnleCjPij*dgSgf9rgjbWZ22wxcEvY****LBDEEBCC94GEJ33422NJQJ2N6721-ElENLlEcAL121121211111119A77669464DCPOOQQFFF*8*HOQNLC8BDEA99775FM9WVcfE6A6876896766oVpCC635D9g********g******lshhjo***HJQ*insVVUUUT**UTRTQTPSSSSSRSTSNOXZTEO9WXBDJBFXWHGSVEJHHLDQRSPPPHIIIUGGOOOOKNPMNNMAC9ABABAAAA9AaQQGFBNNNE8ciftbZaefkeReVHLJICLNHtBGBETHM63mgG9689E7362884JHJ3MXTTZ34225QNphiKFIVONORGGHHGFHFHHe-LHWLRYLWSrL2*lonttk*y*bnWQJYHIiWPKOOPVVAAAAAAAAIIK7DGSI--11111111-5427714622133111134HJJIASQNETiz***nbUVVSbbededbgJY*dYTQXO68TRKGGQDDUFNJWFCND7B39xD687777796ECDDDNSFD8DFBJI99C2EDAE65AC9GCKGmnHF7355166774326322333368315GFmlGMFNeLRHNbikigfRTdWXdaYaicap--25AAG1--111TjdaFiSLOOKMKNMLL-NJNNMONMMKONQLNLLMJownTVPVQMJNONLOLLMNSOPOPvKHGIGHJF-VKKLKKJKLKMJ--5G78677LfPW5CuLiBAAA6A545454438RNRXTKH8BCHFcffei*rkXZWbXNcniA554565556fYejccbYawlgqnegKQMRPMMM545411EJCC77GH1111-1-1L1B161-2-1---21----1-72-12226G445565446PDH B6BDxyQ2uNLJRUaon*esw*t*n*popfqhlijdjqjogosXabum******ciocfiheWMMFKJFNDINGMJJCSMGKMNPPPPSetcnjtmQLSQeRVtZa9U*w*qyndqpXcRfVeW**Z*X***7*o*QeVTqSbgeLbVUUhPR*bYQbvfdeS*goP*l**ZipaOcjc*UVacVyYX*ysmlfrefrT * d.108.1.1 N-acetyl transferase, NAT
[  21] ---4-2-2-------1----21-45B98-42911---------16-2813314-2----1-----1-2 5JW22-------1-12-11-131112111111221222223221E2-11--2--1-------326--2-11-11122212D5-1-F13334--633---73242614741111111-------12223232332334422333383--122731------1--311233----1---1-1-----11---2-211112-12--2--11352121--224112-121111182-222211213112222111121-1111--1122--33--1---------------------------------211---1----------3876F45467354412444411113I31A129-LK372725M3--3-1--5BI64441--114-MQg324EIPJN------------JGMEG5DX111-33369757DC45541126326766623111111112551-LE6--1-1------3---------2--1---1--4451-2214134234422223333242214235646511223D4B55231J2-1173342C5232-212BDA3D64BC95BEB8TJIIQ2***j***5H*tz*IF7A359A55599493731111--5947811DB-68364322MNOPP3JbQURRRNhfSuQ---439C------44158-16777675776-7656566666766666662---441-2545455555554554635526666--322212222111----------121B1833656476545755446111121--21-265869CBHA594CABAC---------25A8GBAAAA7FAGE-111-11-1--11113D3664422--------111-------1-----1-1----1---11-221-12--4J21 12-174C-E37857924548546754385442535475-443-3638866965674455585352324141323434214122242411475455813111546721A54*************************************************W**h**u*****f**A3224X6-453BAGH9H9269A8D4 * a.138.1.3 Di-heme elbow motif
[  22] ----1--------------1-------------------------1--------1-3----------- ----1------------22-2---1-222221--------------------------------1----1---------------1----------4-------1------------------3-----1----------11-1-----------------------3-1-----------------11--------------------8---1-------4------------------------------------------------------------------------------------------1--------------------------11---91-1-----------1-----15--1--------------1-111---11111-----------------1111---1--1-1-111111-1------------22222222-------------------------------------------------11-2-----------------11---------131---11111----1-1--------------1-11---11--11-----1--1-1---1-1--11------------------------------1-----1---------------1------------------------------------------------------------------------------------------------1-----------123---1------------------1111-1----1-----------------------------------------------------------------------------1-------------------------------11---- YSWZ***2*tp*u*****zgnnshkjgtvmpgomton*t*jx*ljjtysuxv**ltpppfpmjfZZWZLfUZZgbZeKcbYefddkjgik*v****ldied*g**sG*************************g******************************************T****vok*o************** * g.44.1.1 RING finger domain, C3HC4
[  23] -------------------------------------------------------------------- ----1-----------------------------------1--------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3-79ZQh-1-----5--1-----1-1--1----1-------------1-121-1--12-111----------------------------1--2---22--1---1-EDG**********************c******************************************-E3192-151BlfV-N42214523 * g.3.11.1 EGF-type module
[  24] ---1---------------1---------------------------11----------2-------- 1--------------1--------1-------------------------------1-------1-------------------------1-----------11---------------------1------1-----------14---11-1-------------11---1-----1-------------------------1------11------------------------------11---------1-1--1--1-------1-1-------1-------------------------------------------1-------------1----------------1-----------------11----------1------------1111111111--11-11----1------1----------------------------------1-------------------------------1-----------------1------1---------1--------1-------1---------------------------1-------111------------------1--------------1----------------1------1----------------------------------1-------------------------------------1---------------------------------------------11111---------------------------------------------2111-1----------------11111----------------------------------------------------------1------------------11 778B***-bIG2VRyKQVOMOOLNOMNOMJOLOKLKJQLPJPPQROMOONNKNRMKNOMNOOLGIJIJ5CKIGGILODLMJFEFFHKKMVXTQVRcURSPLOT***2**v*****************************************************************5A8BT673A6eTWrXjMIM****y * b.55.1.1 Pleckstrin-homology domain (PH domain)
[  25] -----------------------Cm88M4eQT--D1-133334km1S*7UZIP----131------16 Vu*6v79A9AB968DGHAA-AK55HNBBBBBARIJJURaTDYPeQI8BBLF9DKK78811MOa8gMRt*sO9888A9969NBD45989nn*k-v656--8tATK*r*fu-------111-1-129749A57HIW7***xwPDI*6*h**ffJNMEE525997UiGi***W573533474553aOI66575GLYddlcllkkSlimrskYUTRSWlosGOMgGSKDAAAAA**BDDDDDDCDDDDDDDACBD9B595ED554369945DD775685688CCAA99ACBB77777888778877777888987798A55398A8CnVW*YYXcddbcaUOmdcHLOHdSV8APOXP8qmYQI9BHBBB8ED357hSdtkkg99AA8OW*y*VKNquimsHHGIGHFGGGM-*w*u****Oid5XdcihbVlvhcYZbSMXMGQZWXWJYH77877887FHGBF*gi3332211243hv335534543433422225CPXD8GIGCOofmkslhSVWRgf**babdHYjoxdknn-8fiUramNOyrjoiDScgOSLNfH3333333EDNWo*d**bPMubB**hhs4*******V*******Q*O7866666645232232333NO9EQCCVQEkZpmJjULbWaYXLZWZcaVbeWfXom--6GLOM------QLOMKOIPQQSPSSTOP-QRPPPQROOPQRPMOPOONQPQMMHGEQMOMPQPOOPPPQPMPSNLJMLMPA-OJLLMNLHKMML--4F787778988FQ*Ih555644132333238FGEEG8FBFATWpooom***e*z*uxyrx322213312GLWSeWWWXWXeeiinkmhohhWXaCDBD22*7yyMPcc23233223712-------------------------8D698867987*4I -11-GF--2111-1SEILHECCEDADB4444444444434534364KH9AFE8MDDA88BAB532211-4113231----133353222693I4C3778794598E-C5R2----1-----1----1---------------------1--1------9----2-1---131-4-1654L23323pAEiGKM84O2433 * d.122.1.3 Histidine kinase
[  26] 333245IHJNQMFHKD7E9664546DC767B831121251231BE57742G8817689EB7DFD3-22 9FM5qBAHIHMB89HABAA-AH11LXA9AAACHMLOJf*wDHANDJEB8JD4bQYF3F43HHIESEVRRR6BDCCMGB24F7933234FEDB1D333--6GBBEUAG7G2111111-1-1111456775754336JIJIG333LFB9BD9B54634434762A847EBF5132211111211H9B43767IAVcdgdfeciLfifekgWORRVfgcfBKGODHILHIIIL*tBLLLKLNKNNLLLNNHEENOC9L7GF5996AOPHHMNC9EFHFGFC65553236562444432342411112112111115224422126792GL66666977674HHH25534-31272322TO8474857399G7513A5ATHHM2A229DDUKMA6EAFAF5898C69B787R-LJJGKLEQDMI2VGGKKNJORPJKEDDN88BC5556CADDBDDDDDDGEIB8B5655233445--335778567247445134317JGE6CC9AJZZaQZdWMPOPZXeXXWSUIUkYfPdYa35KMK97FBBKFEFNDDG8A88AK63333325265B8BBGN386647A54685C67E65763DA6BM939553-4ABABA45734333334434377II9CBHH4J5EKJGGIEFDKGICGDDLCMN2-35A58---111kRQRJbDfhgegcdgfd-dfejkcdiikgeicfeffRrztVdAKSgXaVZdcbbeadebVdjSQTVSXZ82RBCDIFFDEHIJ1235ILEHICCDF5AEDQ867548434314673MLIIQ8J9BHPERPTSJVScBRQONDTKMPIJKEPEII5DJHFEGFHGKGGFGNOABBB977743331283885555-1------411--------11-11212-1-211---BC8889A9992G88 5214PJF-aF77ECPzx*x***q****bWRTMSrimZUQTPSTVST*so*****v**tbqlqVOM7CC8HCDRCRHGEJGDGIBKM8CCa*bxYfcihiRTJHkVY3J*O*y*w*tjSQOWNRP**JyU**q1*i*MYOY*OQoOLXRNHkKH*RlZa**zpw**v**r*****kAC9F*GFFHJailsshQbR*ozsa * f.38.1.2 LacY-like proton/sugar symporter
[  27] GHEDJNHIMJLLLLJMJKTSSRRNSMKNBORO77HEGAAAAACKHADPCTPKNCMNKKQJKAKIE9A8 MHLCW8AAAAA9B9EDEHH-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 KDBDOGC2uJI9DFJ9EMHIIIBNDGMFFSCHCMJIAGDFEKJBFEFHAFQOMTCGHFDCEAAAA8F94AIEBBBCCCDDBBACBCB9CHJ9EHHE89C84GGIKM4LVSfPRScWZLKLDKSNhmIhK**a1cPlIDCGYHKWMHPHHBIGGMHbPMWHMZKeKZIYHOcFOOPIUJG*IGLEHRTZxLeZFJQLLND * c.37.1.11 RecA protein-like (ATPase-domain)
[  28] 885848TJNPORQRRX9FHJK56KFB9BAJBB5756473445437435338B869CCEGEDEEF7336 AAJGi99GDDF869qTVMN-Or44ijLLKLJOmvuvio**HPHNKODBHMK7bSfCIH55RNf8VMkWfSH25556665299GII7ABBBA84A441444B3FCH7GE4312222142312224JNKLLGGEMHFFCC88224BBQMQFIKGAC99CCE9ACFJ6EQLOGA96788B99978AD8CABA38HHLLMMMNGNHQMNMNMNIIIDDORQAHDBDNNFBB9BDMQGJJJIJJJKJJJJKJJNMKHI9G5GF57645LJCCGFA9EEG6DEEGEEF7876BB25545343325789A97999998879C444ACCGC5D7IDDDFC9DECFACHH7DFDI9B84A69A5SOIQ668J7DABDJ47468OQJJO56545NLlQXGEHGJKTQEEFFEDFFFEH-QNQOSQPPISQ2PEEHOOYJHROQJUJM8SNJFKJHHALGGGGGGGGFHHHEIAD444222214422-1322-13-4--222318FONE4LPOKOcehZecKTNNObbdjQRRR9VicqOdjWAKHGQTfIMJRNWQWIIGJFDBAD95444454EBEKKH9QWEINGEDHKLKJ5B9E9FKEK7FEJFKICX72326121132232222222B45FVFIKIJMPIFAJ9D9BEDCEMFE99DD8EJDHE--69LIK432222OGKGBMBKNNJKIIMKK-NKMKMILIJLNKMGKIKKHNLNJFEDBHLHHGHHGFGHMJKIJPEFFHGKM86ADDCCDD9CDCC112C77767AADBDTCLO777516544438336SQOUSCNCGIHHQSSSQMSUNPOPQMJHKCACAACBAAEHEFK9BB9BGEHJIEBBCGCBAAA4444B9G9KK55771332112294D32347-5253424444576454--16667BC5BACE925 9A22QNR-cCE4EIUwr*d*fni****NMLQOPYRPYUTUUUUNNNtljy****fmkbbXWUHGU9AC9D86ILGDC6BBEJHHKH9BCn*brVYYKPPNKNTcRf3R*T*YugbbgLLNNPRIpiM*K**l1sU*NMMRkLRfUIQRSIVMNgNSYSRj*rHkNPCbHKRUTdRNZTM*NMLZXds**m*VUfTYQVg * c.3.1.5 FAD/NAD-linked reductases, N-terminal and central domains
[  29] -----1--------1-1111112222242224313--1112131-1-3212233----------1--- JFS32-222222-1122----1--23-----1234344485D7F3-332--2251222--634454C559------1-23225B98CCHIIB4I464116G8FDJEIFF333333322333337B85A8977CCC88976544B4EBCCA987588446967876MEDGA64457444554657666446AA9DDDCCAACACAAAABEBCCA8ACAA9ADB88BCCCCEI92332223334333314443427667766676666666873668222222222222222222222222222222232222322222222228HCEEBBBBBCCDCB96PPC7999DB65889C6CBIHDEDB9BCAA55BFI5IHBBG444449CQKWI9IJGKGC45574665548-LMDELHRK9DE2JEEDEBEABCACEMADCA999D88999CCCCCCCCBGFEAJBD88A44666447785558678556657778679GG6CDBBEMILILIMFFFCNNNNJJJJCLILNGNQQ7DQSNELIIIYRIEGBGOPCJJEFC4454444D9EGGMEFI8CBCCEFIAA98DCCBBFOBDOPLPWM8J854445555558799899998A9AAEFFGGIJFNDKFKLKKKJLKMPIHMKHKROSL317D79I554666CG9ACF8EIHHEGFGKC-HEGEFEEEDGHFHEEEEEEFHCCF99ADCDCDCEDEDEDECCB9EHCB9BF66CBBBBBB9ACBA555C8A888BCEDOGJAC767889677586888DDDIDCF776HDGJKHKHNKGKNJHHHKL333333433CDEGHGGGHFHJGLLLIIEJEEFGGA9A973F7FFABHH87787888442--2-4-22-22--222-21-2222297877B8B9A9IB6 RSNP**j2*XbJNNZcefYYebWZaZdZYXZZWXUXUWZXUZZVXYancikiplXdeeZdcdbVbYWZNaZYXWbmfQefXYYYXYdaXW*Weza*bWWTSXQt**CY*********y***r****t*****3***j**w*****t*wrq*wq***y*****u**qb*beefm*cJKXI*KKJNN****c*xXSsssnb * c.55.1.1 Actin/HSP70
[  30] AAAI9ATDJGGJIHHGFBKNSHHJbSOLNBRLCBMLLJLLNNKJHEHIFIYUMKFHHIJHJDBBC1A9 GGSETBEEAA89F6IIJIJ-HVBBPNGHGGGEPPQSMWdTCaZYCFDE9IG9MNPC9CAAHITBMIJQMMIA977ABB7BHIHGBDC9GDOM5KCC61-9HABEH8HE9434433343544445QRPTURKRVNQaXXTX88AVGnbeeedXMLKLBCDEDDPSJNmonXDACEBEBBEDDEINNDC9B7OJBFFGFIGMIEJKJHKGBJEEBELJLGFEO98AC99899KICEEEEEFDFFDDEFEABCFDA8886755777AC67677D48B646666953446335344444444444444555465447556446554FTKJLMMKLMOKGMJOERQGDB8NELB9JIKLNjbTVSREQHLIJJFCE8GJOLFFH6D76EMKSafQEKTVIJUFGFHGGGHGFO1UZXRZcSaOQE6MPOVYPQeRUVQKTJHDSHNUUTWOJKDDDDDDDDLPNFFSKZ785667785546545545966755564675DFHCBCECCMURUQRWOEFFERQXYOJKLENQaaLUVT7BOPJMVIPJKSHPSEGJWMICIHJ7977887BFFUNKGbTNNMQQIYYOPTGOPNMMLWQVJNOLURMRCDA9AABDACB999A99AB9DECDCHGJMHFIGIAGFGIOQPQHHISLMNJOHINLM6-6GMJL352434HJHOHGGGGHFHHGHHE-HFGIGHEFFHGEGGGGEEDKNLJGJHGLHDEGGFJHIHJHGEFLEHDGEFGB6LEEFGFDEFGFC43G977667ABBDLFNDDCBD8ICABA99AA7BCBEDDCFCDCOGILLIHILLFLKLJKOPO899989989DMOSTGGGGGRLMTPFDIDHFEGFH988B66TAGGFEFFKRMK89G8G5522224-3293432323335231222ACBCGCCF8BCJCD CFCGKHO4hHGFSOHOSNGHLOIOROPDCADHEMOMHPLMQNMDIGHEQPUTbPJLMRGJEHHNJIIEAIDCIHKKGCEGMLLJKJJHGDaESHNaGEECEOGIMH8P*TnShfUXOJKIJJQOmZHeM**U3cNpNOIHdORXKJNM9HWCGhHNIKVLiaDVKPHMFN*HLPSJSYQ*LNKSKXbknGYXOUkvaWS * c.37.1.10 Nitrogenase iron protein-like
[  31] 76-4--CKPLNOQMMF2185774QH66842BC54A1--66664BB9DD88978----1113877---3 6BD9*B9877AJBG***jj-i*GG**jiijil********5*h*734B6I94JDQDEN11sdP8*f*ql*J4343444-6FEN32432CB9A-C331--5J554p576611111111111111256568536785IHHHI555*9INK8MNT2233443433633AWJwA433333353333A77CC--3FAjGGIGJOENIHMJNSF89LLOWGHVCLFKE77444444y63888888888888886765631213212121172222121333444223325218612211111111222222222312212212222224---B3333C33142a3BB11213-A22B62C3IFA4C5-1F81115-21C5ATFFQ11111BAwc*A68khjcY46674465658-JHQJIVFGFNQ-FFFKABCC9FRBIXAI9GIQAEEEFIQ44444444D9336KEG----------111111111111111----4GLjH1CTRGPRacbcftRZZNOMUc****RqkSsku*h56NNWGLLKHkKRVjg54N3144K7332222286ESHL7wXQGEHGBJDBBB2DFD8E99ACDFFD*hCG33321333332141-11-111442743EI48EAE8B99AABBBPEEAAABF9DDBFG--16DC4------K7ZFA87AAAMAKKCBA-8BBBAABABC9BDA99AAA98CQD**897899B999A889899F67788871-9AABCB977ACA--1746685BAAB6Ef7O333263133323334EEFLE6G9BAVFcgYd*plnKVSYVBgV*7444454543678KCDDDDBD8BC98A67666665444--63DD666632222222411--------------------------2--------2I25 I667dhG-dHAAKKo***x********hiimop***toromuohhf*n******yj**hXVVL9C9897DA8A8CCB8AAABBBHCFEEp*X*ZVRA8B8EDbdcd3P*X*l*j*esSQOPTYR*vNwS**n9ug*VVSVdRTiUKTTPMsOLmRZZTkVg*R*dqooUl*YduO9EKH*CFFLIeji**qwHHmbcWn * e.23.1.1 Acetyl-CoA synthetase-like
[  32] -------------------------------------------------------------------- ---------------------------------------------1---------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------11------------------------------------------------------ 1222--Q-1-----------------------------------------------1--------------------------------------------------*1-**********************Z*****************************n***R*imqNm*7---1G1-----------1--11-- * g.18.1.1 Complement control module/SCR domain
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yGJGJIMNLQPOTSQPVQQRPPPPPQQMOOKMKLNNPNNPNPSSRVSOQiNLOMMMLJLMDNMKPLNPNFRRLJLNOONLOOdMLMMKIKJLIOPPUWANgciUiSaZiPMNRLTPnnLnN**W7le*ORQOkPTXRKSRPOWKNkVbURXMasNPOSQVONmQaQPLOQO*RNRMOcVp*QhVRNdfTWO * d.104.1.1 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
[  34] ---1-1--1-------1-1----12147-21--1-1--2-221-1-4---3411-13232--11---1 21F15------1---6411-11--1111111-1-2--218-1--11---11114211---112-312535------1----111-1-----2----1--111-161D14221111211-2222212--1----1-33336-114-1-33411-2---2222114235577--1----------1212-1111-111-112---11--111322---3--1------1-12111---1-1-1-11------111----3----1------1-----1-----1--------------------------------1------1-21--------1-----11----1211-1-13111-1---1221-1----41H2--1---1--1111-1-1112333333333331--2-2-23-222-11-2-121332-22-1112111--2-----------111-3-1--1-------1-111-1-1-----1------111--11-11-121--1111---12222132-12111----31-11121--11231----1-1111112-1-1-2-14314-211-22111112--11--421BE11--1-111112-1---1---------11-2122-1-111-----1--1---------1----1-----------2-12122-1--111-21111--1212--11111----11-1111121-11321131211----------11111-11211----1311-1-12113--------------1--222332--1-2--1-1-1-1-2-1111-1-----1-----11-1-11--2---2112222453------1-222243--------2--------11---1-111-----1-----2-1----1-2-2 NLJQ***2*fpU***ouywonssyyuzzutyqumknvtoqintosrtuxqw*ysr*qyru*uohYacgGhjceffhYAYaegafekjjnq*zuos*sspqcml***C*************************T**************************************r***Uu*r*svr*x****p**t****** * a.118.1.1 Armadillo repeat
[  35] ------------------------------------------1------------------------- 1----------------11-1---1-11111----------------1----11---------1-----------------1------1121--11---21----------------------1------------1112--------1---21-----------1--------------------------------2223-3-2-221--11--1--11--13222222--------------------------------11--11----1-----------------1---1--------------------------1-1-1----------22---333---1-2------1-1----1342---12-----------------------111111111111-------------------1---21------------12---------------12----------11--11------------------------------------------------------------------1--------------------------1-----1-----1-------1--------------------1--------------1-------1--------111-------------------------1---------------------------------------------------------------------111-1111----------1--------1------------1--------------------------1-----1-----------------------2222222111------1-11---------------1----------------------------------1--2 ---1UM*-F83-fe*FINGNKLMLJJLKKKKJLIKHLNKMOHMJJLPNMNNLOKLMQKJLKLLIOJMI8NOLRGNKMBMMNNOPNQIMNLgSIWSeLKLLMcQsnu1*FC**********************l*********************************u*******r--2-11--224599I53-14434F * b.34.2.1 SH3-domain
[  36] 55132311211-323-4-555665D2258-58---2411-122111-92-1-1-1212131---4-41 AFH7*339BDG23223311-18112V1111119888AIWVFfE*erZ1ORK8gZf22E22HEUCkBdqreCNHHHOTQ6---H112--98CB25221--2E183F4G6I-------1111111111233311731HIHED332SB97997773423344342444288C912-11113-1-1KL987KI-KEEGGHFGEDGBGHFCDGMRJJHGFGCAOS8DCBABCCABKt54444444444444452278HBC5DD5F74AJJCCBF977FIA888CBCDDBDA99AAAABAAABBA9AAAA999A99A99CC887CCCFFE8BuAAA9A99DAFDD448CBEZB873D2H85BB7B96S64AGCIL46953DFDD412212H6***63AdIcgRPRPWORRMRQl-BEkCArFZJ*2-*ttm********WbC26RTZNMNQSJQ33333333YHI36E4H----1-------22221221122221---44A882IYTJUejmlpfQMNNLcc**TRTSKVfc*QdcN15XYXe8PKNbcnSx*9DC-513FA11-------1CHM5JG376K96MN89A4968B8D77555557a2N3-113234442-----1---222--11IIS99EE1D5MABBBD58A9893678648C---3213------bYZVCZORTTTRSTTSQ-SQOTUQRRUTSSSTUPUUQoppUVCEEOOLLMNNNNNMLNLKLlMJLKJLOC-XcdddefYceef---111111323333SFYABAE8H27898BCGD------4232SCBBBCBIJVCIELEBSOP2--------4GDEXHHHHHJKFNNA8CECEEAAB3433--AB--11--76656355457----1-1--11--2221---22---CHLC78TAE9-b22 4-223361E9*134A11222453121322-23-2---3122222132-3111332314-5643-11-3-11141221-----11112-115-1143---14-1657-AoB*******VPQQX*W**L*V**s1*j*QbRO*PbgSHbSTNsIH*TfVe*9EIa*qaOlOP*dsy*254-3---11KDD*2T84167427 * c.93.1.1 L-arabinose binding protein-like
[  37] -------------------------------------------1----------1-----1------- --1-1-----------------------------------------------------11---------------1-----------1-----------1-------1--------1-----------------------------1--------------------------------------------1----------------------------------------------------------------------------------------2------------------------11----------------------------------------------1-1-1-1--------------1------------------------------------------1----------------------------1--------------1-----------------------------------------------------------------------------------------1-----------------1---------1----------1-------1----------------------------------------------------11---1--------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------1--------------------------------------------------- ----1----------1-1-----11-1--------------------1--2-2111----------1--------------------------12---------------**********************K**************************QLS**txu****LTgB-1-1-------1-2---1------ * b.1.1.1 V set domains (antibody variable domain-like)
[  38] 11-11111-----111-1-----333324321-233331111-44-133253321113222112---1 3541211111111122211-13--3111111223333345-2111-12-111112-----22-121345211111-11--111212212224-223---1147511-3----------------31121322-421111-1111-9A78444235544456445326765162211161211113------41334343353444444132112424222123211111111--------------------211--1-11121111--1-11-11---------111---11111111--------------2211-222--3-1211111111-2-1112----1-1111-1-11-21--1--------12142112-----22321--133422----------1-333331-5231-1---132324222242222--1--134111111111111132-------------------------------3221-1111-233463-111111353333134221313-211113----21-1---4-11122---------3112-4523232175112-111221133----1-1521111-----2-111111112-2562232-443422533222222622234255355--1-222-------1--31-1111111111-1111111111111111112111----1212111211121211211111111--111111111111---2---------13523---------------11111-12245-222212132212233122111-1--113234111114544511222221111111--5-11--11--------1------------11----1---1111111211111112-21 2423C4L-J97164A44544896956643112122233332223316843449833341444641122-5324-333222322334-217B3497B5338664CA8-4xK**********************D*****************************************n5lkZ*MNQE7ITJ*4tMTZv*w** * f.14.1.1 Voltage-gated potassium channels
[  39] --------------------------------------------------1----------------- -------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------1---------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1----------------1--------------------------------------------------------------------------------------------------------------------1-------------------1---1--- 3634KS4-61-1BBTA6HCDDEDCBCFBCEEFFBDD9DDEBDEBBADFBHHFQJGMFDEEEEDAADBB5AB9A9CBFADFCBAA8A998IJG6OJG977CAF9ebhEC*M**********************I*****************************************fF89GWDBC58****H*n6FAJOM4 * a.4.1.1 Homeodomain
[  40] 663655ACHIIIHHH98OA98889G34I8EB7B99756766688B6977BEBE8BCAAA4A875A-9C HK*8Y98CJKOD9CFRPFE-EY99OPEEEEEISTUUJOgbIIEOdeY8CMIFicfCEM44MHIEVHTOfWDBAAA79866A4J9ABC9HGQI7V563456H7HPWBrFZ5555555444444459A9AA799AC8IJJbV777HEEEIJDFDBBBBAA8BA8BF9EJJLGB99ABEBABA8CCB99AFE7DCBIIKJKGGL9JGIHFDUIGGDEGIF9JKELDEGFFFFDKq97777776778876747659D7339C46644EK45CC668988BBB66665759678778888888745555444444548456654447CD7AG8888888CAB9CBB9775IAB74CAD8AED99A9C877DCDD528GGlHEEC58878D9JOJD9788AEBKKJKJIJKKKL-LIIKJDIJNW95bVWLZbeifdZWBCBA9HPHECFFOII88888888EFH8BDB7443876773355222232222222253437BGI99BDB9AHHGLIHHACCCHHJNDDDD9FJHJCDJD78FDGMD7EBFEDDGO9ACB979ED98AAA9A79A9CF6DCC988799B7879CCBDCAGBEJHJKHICI987679878968A88887888867998EEEEBFB9HGGDGCCCDDEEDDECCEGEDH3-4CA7B855888QHGJFIFIIIHIJJKII-IIHIIHNIKJIKLHJIJJHWSUJLOHEHHFFGHHGHIGGJGFFPGFFFGGK75HMLMNNLHLLNK667877777B879BAHGQBABC8D77876999D77887687BCQCJKGHFIEJJFEIIFMHI833325433AEFDHHHHIHFHGGGCDGGGGHHFF899966D8BBEECC32223222236111-2-1112121333112212---6CB97FCHFGAZCB 5532ABC-TDA5FHMMPTIUTTPjYbOGFDFGGHEJFIGHGHHEFDPMOXSWpaRSKJLHIHAFF8CAABCGEAJFF9FHDCDEGFKCFNjLPOIReTUKFHJJMN2HvHZIXIKJECD9BBPCu*AmGv*M3VNr9EDCoCES96E7D8I88ZBHAGKCGJDWF9FLCCf9CL8KEHJ*EEAHKwawlMiXUZUXPTQ * c.2.1.3 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
[  41] 66345679DCCCDDBB5664665445644475A87696668883555757A95696976763565275 8CF4N59AAA768688988-885599988988A868IIAE6GEO877A46C8BAA858667BB9F9DBGD776665A77769996856CBDG5C675--ADC77G579A756666556777776977C74668987BB8A884GAKCJDFC787AB77997A9I6CHMHD676766687676DDDA9769688EFEFFCHF9GGHFHJB8BBBBFGH989ED9C999997GDA99999878988989AABA9FD8AABDADBDAACCCE8A9ACA878CAG8778889888BAB9A88B87779898798889BB887B9A69BFCBAA989A99A7CCDB5D99E6A8979B7989F7A8B98688A798A98AB88C54447A8ACHB98799A866786667678-ECEBGEFDCFE9G88AC97HBBABGK6AABFBCECCA9CDDDDDDDDA9AC8B8C777555554459669897B786786A69878AA9A8B968EGGJGJDCCCCJIHDFEDEGGKNKEHIG69A8BFEB87HDAB999D9BB7B9E776675778BF796DE6A7BC88GFC766999A9D7GDDAEHKB86848888988865876765856667AB6886F98569BD99BC679B9697867ABC6168988452767A8CD998A77CADBFAA-7ABACEAA9A7EAAAAAA9BBBLBMJA57657756676A8656B769996A768A9A9AA9AB996788777769CBA77K7878876767868888868888868AAD8DDGEHDAD8DACED8AB666667666C668A9AACBAAAHCE8C9A8AAAAA88977FB88998688877775749JKN88-76858985556767796669A7797A7865577 HB78XLd3*SLIMPMCKFDHIDAGKEAABEB9BEEDBF9FDDE858HDITUTSUHFINGIDG7DEBCD8D9B97DA97B99EED9DDCHCLIKVFXBDA8EGGHHH8Jre*******vrkos*r**j*s***6***oqji*hv*hf*ptl*fj*l****fv*o*tgQyMb*WipdDOTF*C9EFJgYYgRiXHJPZQRN * c.37.1.1 Nucleotide and nucleoside kinases
[  42] 433957A67887878765798784CBBCCBBA542232222253223323364334454443444389 -2-11--1----1-------------------------1--12-1-------1---1---222--------11111-11--11--1212211-2111-----112-1------------------------------1-11--21512-11111------1-14-211-211--1--11-1---11111-1121111111121111111K111111122--112222222122222222222222222223212323333222231122232---3442222222233222222222222221222332232122222322221222--------1-1-222---1131-5311111212-213122432-11-13223--1--12---------------------2-22121122211-211121111111113112112222122111111111--11321--1-1111-------------------23-1211111112222322322222222222222222---111111-115221122211--11-2122212221213221---113--11--1-3131222131--11--1--11111111------------1-133--1---1--1------1-1-1----11-1----1-11-1-------11--1221111111-2211211111211111111------1-1-11111121--1111-1-11111--111111111111---1---------1-11-111---------11---12-1------111111--21112---1----------122111111-21111---------------1111--11--------2--------------------1------11----11-1-1-2 856997G2H577CHECHGEAIEDJHGFCCCDHCGDECHDFBFFEDEEEINFAJODDGBGHJGEDFGED9DHIHEGLL9GKGIIIGJBBBEiMHKLMDBG97GDTSW8CJ7**********************Q**************************************Tg*S88A8y78778FLNKDIA98CGAA8 * g.41.3.1 Transcriptional factor domain
[  43] ----1--1111-1111-31-2-1-511343212----------2-215--331-232-2-22------ 64E3H8BAEEE95874877-7822AD7777777777ILCB2G9PFIFBB9769AC37H229FABP5CNOX78888898G6XF3222117853-435B--4C754D5D7A1111111111111137567B97C988788AB322I1IDGIAAB4488A899B99A8ENWYC5C777769576753722D84A39AADADBDE8CCDCCECEEEACDFI457ADBBEEEDEEHM86666665666666665446MK6DMME4JEPDD55QS96467AC9B8ACIECEJDEDHCEEAEHBDB67866677A7666FJIFGCFFH9I8DDEFFFGIGF5FAHCHH5DCES99HNCFB2-TTD2225422AADG66591566654545563FGED885D9D8999A99A97AD-EFIEFFHIAK74MFFEJMEKMKEGEC66587HAABAFBBCCCCCCCC9576B97E223222223346446746655555534531468246997EADDEGD99AA9AA9ACCCB8AD9BD8B523668C87859798C87BB4B48A625346348789A67573636638722213635677373353AC19744353333332144343334523488BA8A63A386A7888786798879A8E879--74984222222A6B8759688D6BDA66-86666676888C966666977CDGGJB9979899999999999A558555653EDFEFFDCDDFD113224322698742D6D6456882576524473445446437BF9BCBGEBC9EFCC4BCC5444454343877F88887CADDE57C6976889444432A3774444--------o-E221261432265244242722533365C667A7872725 B9EJfWP-xPBAgheWbaWckuf*uvlRRNPOPjoeSVOTTSTLKIhek*uw**hapdbUTWWOJBEG4KF9KHPEH3FJBEFEOKCFFe*KbdjXRPRbMJZkjS6N*l*p*m*s*aXYUZeW*xP*U***1*j*UWYXvWc*nRYVYRpWM*coXgrZ**b*cRa*ek****wDQNE*8AEPI*up*a**QV****k * f.37.1.1 ABC transporter transmembrane region
[  44] ------------1------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------1----------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------- --11538---119ACDGEBAFFBAECKA9B8AE689BH7C8BE79A9KDERJPPDJIJDFIE76B8575C97E5A5748A8EED8D444BGFGFKH566A388m*w1991**********************d***************************h****py****JQ*G-1-2M-----A699F77--B6771 * g.37.1.1 Classic zinc finger, C2H2
[  45] -----1---------11-------2-----1------1-----32-21-----1-----1--1-2--- --------------1---------1------211-1-122---1------------------2--22--------------------1---------------111-1-1------12-----1--1-1---1111--2------2211-14----------1-121-1---------------------12------1----1--1-----------1-1---1--11----1----------1--111---------------------1--1--------------------------------------1----------121-----1-1-11-----1---1--111--22--------11-1-----2---------1--12----1--------------------11--1-----111--11---1----------2----------------------------1-----------------1----------------------11-------1--221------111----22-----1-1-1-2-------1----1111--31-1-1----11111--12-----1-1----------------------1-1----1----1-1---111--11---1--1--------32---------1-------------------------------------11-1-----------------------------------------------2--21----11----------1--1-----1--1---------111-1--111-------------1-----111------------------1---11----------------------1--1------1-----11--1----1---- 1--155o-HB5176668695866847654598A567998869A58757BCBA8D888778C951122211--13-2-13-3115-21-27B68G7D5757474597-H48**********************r**************************dy*****w********255-I5224271378433549A94 * a.7.1.1 Spectrin repeat
[  46] -------------1--11-1-------5-5-----1-------22111---------3---1-----1 1OV3I32333313258676-6633B86666666788E4D72GDN3431144222212222233177A86C71111111111262-1----2-----2-----1---1--11111111111--1-------112--55597---826137--3-1---------2228687------------11---111111333232321443223132312233123221111111121111111-1111111111111-1-11111111--22-11-1111-11111---1-11----1-----1-------------111111111-2112211111--11112112---123131111122212121211111---E-O----------12-----2--1-------------1-1--21---------11--2---2113--------11---------1--1-3-1----------------------------1-1----1---23----2-------3211111--1-2--1-111-24---13214-124-112-----1-------41-524------1--1----1----15896M*-3-------------1-1--11--12--------11111--121111-111112121-2------2---------1---1-1111-111-1111111111111-11111--------------------------111-11------------------11111------3-1---------------------------2222----11-1111-------------11-------1-----1-1--3--------2-1112111----------------------1------11111------------33- JGEGYMk1*mScZPSLHQQKMOQececZZfelhicavTcRhScYUVTTPQRbNVVbKZSSUWFGNEBI7TJ9KFDMGDOHDGFHMLIDDUnPHcXpHHFHLXOkj*4**u**********************B**************************t****x***ms*v**RG**K*FFChS****K**KQv*beT * d.144.1.7 Protein kinases, catalytic subunit
[  47] ------11-------1-----1-------------111111-1------11-11-------------- 4773U525AA9422F7743-47227T44443699A9HTal-E4893352531FCG237--7571L5bJUK51222232339C4111112221-211---1612261315---------------1------1-1145534---31F44755733441112114638567212111111111133222--143FCCCCCCCC7BADFEBC6CBFHDCD243D493877977Pa1223344134222446343887577645512EI668546634563633332223322111111111122222221222221111111115-54DF6665685455287732237411265722JL452313632221-14423O88A11111TKnhr77KMOFKEGGHFFFHEFHe-PUfLNzTcUs9-*ssfkln**x**yjGB7ISjGFHMFZfFEFFFFFFHSRFC8BH-----------------------------14Jd98b**********xqprn********c********25*tnTOiRU*e*Q*hLjC5ABAmK5655535445BNID461547525C875-615747663FJ7LKU144132-1111-1-1-------24323CBgbUMNEmETNJXdegbJZldbcWcZkgV*n2-2665B1-----bWhqKcWYXWUYTWSZW-XWWWaUSYXYXWaVVWXVN***jcGJMbSZRZXbaZZWVaURV*OQNNOMP9-VNNPQQPMPQPQ--171311388A85Ajj*BABE6G388867557efdheMYAFE*E********l****Quq*7733377477QaevSTSSTdkpbdZbQTTTREFE7333--6222------------1-------------------------------1-----3911 -------------3-------------------------------------------------------------------------1----------1-------------------------------------------11--------------C----5-1----D-12-1---------2--I-----8---- * a.4.5.8 N-terminal domain of molybdate-dependent transcriptional regulator ModE
[  48] ------21----1--1---1----31121121-1------------21--11--1------2-1---- 312-O--31112-2QnhLL-Lr33niLLKLLLpqvrQHUb2RFr2-1211--3181-2--SI9-aAcbITB----1----1-2----1---1-1--1---1-2-2-311-111111-------1-------11--13321---D-B753772--1111132131-446B6-12----1----42411----173333368444435642366383431---1-11-----2-111111111111111-111------------------2---1-111----111--------------------------------------1-1-1111111-1---------1-1----1--21-1---1-------1-1-17553-----22IEC11-839A51111111-112-45A5586849A-344578A24333213932922234345---------22----1------------------------------6GJ7--11111222521333344253333-44263256--32121-3141523-----1-12---------2131212----1---------11-1---1--1-7Q1------111111----1--1------------2---1--------1-----1-11--1--1-1----------21----33--------3---------3-----------22-3------------------------------------------1111111112233-----------------------1--1--34432221-2--11---3----1-----1-2-----2-1-1-113333---2232--1-11--------------------------1----------------8--1---11-- 1---kt9-D542A9C************cdZfZa**zcgcechfbba********rx**hcdcK8B6544854B4A4534449AAGC323*******44597FOfsr-Bo********mcbmr*z**l*o***-*t*Xgje*bb*xLbZfb*gS*i*p*****j************5SID*AAAQe*******8EYTRXB * a.104.1.1 Cytochrome P450
[  49] 45323365675666665A89776677776596432643444339867968878345367885455-46 8CK6OA988884A4CBB99-9A559K98999ABCCCEHJH8C99DF889885GFF99C11BCD7IBKPOL8AABBCCC478H754433BC9A4B441-24B458L4D5A222222222222221565775466559BBB9667A898A999A89884564457999EDDB4534434544649AB8955387DFFGFGGGJAGKFHII8EDC8EFHIDC8G768977978UI5887878788888878776A7453AA3813-BA88995515A3565555434457744444444444333333333333396775766666HBAFHHHGHGH6E79JCC7999D89376CB77DC8CA5578788A7477B78DAA81111187LHH566BB9B9999A999878L1DCFBGIDGCSA1ICCIHJMKKMHKGA8B5DDJHDGIFFQEEEEEEEE8BB95ACF21111111111211221111111113161448F4DKSMGMaXYVVbWLOOLZZfhRQRSFNZSYRRWR46HINEGHCCWHKFQGCGC898AEB7666676657ACA3CD597BB7BCDCB1C7AA898B8BCCCKO7B622235344322523324235453655BAA8E9855687D899559767856B987E2-17977111111DEJDEGDABBBABBB9A-BAAACABA9ABBC99A99BJMKHI8A8DACDDDDDDCDCDCDCO89D888771HAAABB9BCBBB222412111665788GEJ556455244433335CDDCB89889C9NMPMPSNRKNNNKFIIJ7354354334988B77777ACFCCBBBCACC8A934443377997789--------211-2------1--------3-1-----53666655554986 72--bPS-OB8DDDEABHEQMLHXSTRHIEHHIGLHFIHHKHHFFFGNFOMPXUIHGDEGFFAGCBBF8EEAH9FCB8BA9EDDFF99AIOBBLHDFDFFDGAHHN1Go**z*t**kfKWNVhW**K*a**w5*s*JYXJ*PeyYKnNNIyQC*gpVbzkz*NzsQTULP*bf**DJIB*CDDEJfUh*IfUKQaRXNU * c.67.1.1 AAT-like
[  50] 11-3-12411111115-21--114B4648989-223233333466356439653445354452112-- SLh3M668666868eOSJJ-JO77bQIHIII9PIGJ99995BAN64757753998347227AB4B65COG61------12523AA8EEYacU2b8E2--BbESKmSiKP222222233222228A48AAC88AIC4444464442HIDCECC5466666C9A8E6UAGNA2622222622225654444498899A9A7CBCBABCAA5588B8BB8858B5A8646666FD46666666666666684668-222112-22222--11--2-3------------------------------------------------2E28F333333343423774557424224468466C66688242225484U9WZGGQ44444SZrhxeNdmgicXCEEGCGGCECI-ovZbsjnkCMW2cNNTRRTRRPJOOiIOQGCJDDDDCACKKKKKKKKFSPLIGTI44344444442242664764448745245688JKAFGCCPYgigiVOHGGFWVbeNNNNGPbShVhfp3CfgaJbOKPoZRIOIOYZOVNQIL5544444MHSVabJSQDDEIDAISCC84IRCKMPRLKQROOcO6QK97668888898A8888888JC8CLKQOKCeaSlWaTEVacdaccqoccieYo*mqe2-4ROGO------IGFIDRGILMMIKKNII-HKKIIKLIGLJLJIIIIIJSUSIH9BDGDADGGFGGGCCHBEDPFBFEBGH5-LGGGGGGECGGH225P8A888CKIKfSXEI444456444344554IILMICN666PNVXXZXTZaVbbcRPNSU644444444PEPPSFGGGGNWaUUacUOXPOIMMDBBB78PHSTCGOP6666666684-----1-1-1231-222-1--22---654A988888KSE7 335533C-711-23133342342222222312223323332332331242323227322332242231222-22212-22233333-2144332242342414341-1W6*VRRUVFGECDHOGQN8RBn*Y2RMZCIGGKCIOF7GEEELE8VHJLNZ8Dc7eKH8FFElx*T8-547UAAC63A43J43365M5C5F * f.35.1.1 Multidrug efflux transporter AcrB transmembrane domain
[  51] ---1---111111111------11A225-3422221--4232459413--G63-1--1-1-1------ CEF9*KCEGGJOEF***qr-p*AA**rqrqq*********7*W*poOKKTOFPYXPAh--fimA*u****KA7778A94AUgE544327573-333---3E536T4F8B------------------23-1136147668334U2V4BE7811111--1---231JBBI1------------D7F453226AJUWVWXTbYGXYUTUVNKOOMLSVY99ERM7ACDDCB9gn3877A7777777777C46CBB6I5GF5A747NP55FF9A6CADEHE5664435FIG334336333344544544465454G4433344444J9SbDDCFDJG7B58HMM4445J34479664-YUE534A8341233384F36*TUU-----WOwWh748dQRRK8888877888N-JJPJKcJPAke-nVVUedSpsoQTPPDZDBOHGCHHDKPCCCCCCCC8FG8A8EI------------------------------6cmH37SLHUlntotgOMLMKUUZcOOOOCP*PxZiie12OMOBEECCXCTIZJ5G76ACCH82222222336BB98*MY62894BL777-484C99978GGEKVZ4A4-111111111-1-------2325934HI8CQBQ9M99FZJIFFIIIHHJHGIJFQH--22734------EJDG8IADEEHDIOGGE-FFDGGGEDHIFGEDFCDDBNRNHGABGDCCDCDDCCCDDDCDDNDEABADFB-AsfgE*ehY9E9--161111122225LV9K844646233233133iikmlNJ788E6fgbfNdYcPURQNEYXV---------3BHFODEDFEHHKIILTGGHFFA9A2-1---58TTAB99--------D-3------------------1---22244522242221722 ----21------15-----------------------------------11--3------------1---1--1---1--------1--------2-----3--------1--111------1--1-2--1------1---------------2111321---2-2------11--12-----1-122B221--B2--- * a.4.1.9 Tetracyclin repressor-like, N-terminal domain
[  52] CCABA8CCACCBBBCBBABBBCBABCCEAEBCAA9A8AA9AABAAB9ABAFCBAABBB99ABBCCABB AAABEAABBBCCBCB9AAA-AAAA9DAAAAA9F999GCCDADEDADEA9BBBACDDBCDDHBDEDBBBFDB8BAAA99CCECBECCBBEDDB9AAA949ADBCAE9AAC79999997878888988988778778A99ABA9BABCA8A88A97889BA999887998899BA8979B8988EFFDDBB8BA8DDDDDCDDAEEDEEEABAA79EDDA99C98A888899AE899999999A99999988999AA988988989999998889979998886586877899999A888988888889898888879987777BCB8CCCCBBBABCBAABA8ABACAA89B9ACADDE979B8AAAAAC98BC8CCBBACDCCDCDFEDCCCDCDDDCCCCCCCCCCD5AACADDCEECD8CAAAAA8FBA88BCECCFEFFCEEEDFDDDDDDDDCDBCECDCFEBDCCCCDCCACCACACCCCCCCCCBDBAEDBEAA998ACBCBCCCCEECBBDBEEEEACCBB9A9BA9AAD99AA9AAA99AAAABA9ACCBBCBBCCA9ACA9BDECBBBABCB99CB9BADBABBCAACBDJDCBAAAB9999B9AAAAABBAA8ACCDAADDCBABB8DC9C9999ABACBB99A9A9BBA799BAA98B888DBBACBAB99AB98AB9-ABCB999B9BAAB99B99BCACACBEBCDCCCCCCCDCCCCCCABB9BBBBBABBBBBBBBBBBBA9AC88888CCCB9ACBBBA99878B9798998AAACAB9BB89BAAAABBA9A9999CAACA99899999A9AAFBBBBBDECDBBBABACA9AAAAAAAAA9AAAADB888ACBBBB99BABBA-B899AAAABA99AB9AAAA9A9BABABCA9AAB HKBBIHJ-qGEBBBFIHPGKGJIIIJMLMMNPQOKLJIHHJHHKGIHIHGJNOXIGKODEHGGIGGEJAJGHHJHOI7JJGGGIHHFJLEPDHNFPBEEDGQFLPJ9IbMpHZNLWaMILLLQJfWIXJ**T7RRdKIJMQHNWNEHHJGLHIbHONKTOi*HRYMHLHMqQTLPKIMI*HKIGJNUceIURGOXNSQN * c.26.1.1 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
[  53] 55643645978777M5388565586449368765738B6777A7644A6A59549A75557556B17A 8HI9J666998675KBAFG-FG77MLGCGGGGKEEEFHOSCHJJ6D884767HCE86C44OEI8QDTPPTA3222444-4768679A8IEDG3GAB111CGFIGJFN8N54445445475555599ABAC9ABB8IJKJF222HACAB6AAC68779A9767A987CCM998878778969A97776557C9JHIKIKHHFEJGIGIGAEJIGGGJLCGABB88555655IG59999999999999998879122-12-4111463321251452333112211124366655465556111111111111153333333327C69D555666895875CB7332559237697C86A7CA564655A7433B8CIEEG64446EDOGLCEAEEEECDEFHDEFCFEF1CEICDMAKFbE6KIIJKKTLJPLODG9B9DHGEEFFHJNAAAAAAAACDD89IBG5565655555222233222422222434467ADC9HLJGJQQQPORKNMMKNNPTSRSREPQQOFFFE78GFHGHEA6FDHBJHBBA8789NB7777778A8B8CA6DEHD7CAAFICBA9ECBGB9HCD9ACAGIEED8997AC9AB8585556556BA6B999FB8AACKAB9CHBCDBGBFCBBCBDCCBHD413AAA9442434DEGH9FFDEEDDDDFEE-EEDEFEDEFEEDEFEDFFDIJGJPMP9DCEDEDEDEDDEDEDCFCA9FFDD96BBCCCCBBCCCC2267ABAABBCCCCAICH888768655558457BDDGCBB8B9DAKLLKJVNOFMKMIEKOLB9899A999BFAACCDDDDEHCDGBBEEEEFBBC666666D7HHDDEG2222322363211111-1111111222211112---5677866565BD8E 6643JGG-I7A6DEJHOMILKWKbUXKJIGEFEMIIIJJJIKHGCGQJPQQUeYNQNJIIFGHGICFGIBCECCDFA6DDHDCCBGBEFBSFOJFHJFIJDRGILL5KgNmXXQTTTGGKFINIbZJjJ**Z4VSmGJJJUMKKMHLILGTDFfKXLPQPdZHhLTLKHDnNQLMEHLG*HIGGHdYo*KmTQJVNOJM * c.67.1.4 GABA-aminotransferase-like
[  54] -----------------------DZ89J4SPJ--22-133234IY-GY7KH6B-1-1111-------5 EYw5L3343335438AB66-6D3389666655CBCC8BCA8FEKF953366478B234--DDP2O5CMIJA122343364E69-3521LMeI-T433--6M5CDoOmbd-----------1-1-7529747D8I6jhfdbF56r4*ex*bbGIHEE233786PcDW***N252322252332RF955242D8FHHKGKIEGCIHLMMGFEBABBJKP7BDG8BA865666aR55555555555555553354324266222-35533453334323544443244421-----1-----333332223323323322132335I8CVDFDDFFFFDG8OJI6797D7F21E88H4MOI9B743751136123W6Xkbba45557JMehjKGJZXQSY999B998898C-jgzecglqGPT4KNOTUTLaeUIMORPFTG8HIJIHALBAAAAAAAAC98B9*XX11112111225A2133332223333111228MMC7AFDAFVRUUdSYFHIGSRegLKLNBMaViOQSN26IJGlTZFHccVVV9GISCF9CVG111212187HJb*UugJGGjV8*ZXXc2*k*pkviJZus*v**Eh35352111111332332433CB43A55PKBYQXN8QMEODJJGCKKIJGFJGGLGML--4DFIE------EFECGGAEGFFEFDEEE-FECEEEEEDDFEEDEEEEDFIF9DAB7EEEEDEEDDEDCEDEEIDDBDCDE6-GEEDEFFBCEEE--474444456559HmDR444313121122113ACAAC6B579KPabjaTlbfVcdfdccTW2111-21-1DEFFKMNNNNLNQOPWZYZbZXPSS98781-*2YXCFLM2112122221--------------------------38132534543*39 ----BB1------1KDFFF9ACBB7A744332345544444454448B99CD8D7B856667421----2--221------22212322654F2A1678794645A-91711------------------2----1-1-----11-----------1-8----31-----2--31-755S12223h47NKCK82H2422 * a.30.2.1 Homodimeric domain of signal transducing histidine kinase
[  55] -----------------------------------111-----1----11--1--1------------ 112------------------2----------1111------1-----------------111----111-----------------------------------------------------------------211---1-1----------11-----------------------------1-1------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1--------------------1---------------------------------------------------------1--------------------------------------------------------------------------------------------------1---------------------------------------1---------11------------1--1--1----------1--1111-1---------------------------------------------------------------------------------------------------------------------11------------------------------1-------------------------------------------------1----------------------------------------------------1--------------------------------------1-- 23-2vpL-2-21MRVCEAAFCFGDGDCJIGGHHEDEDABG9FHHEFE6EECCG799GDCADBD89597399694C54174599997EFBGQEEGDKGHFHBHHYbN-*G3**********************P************r*************m******w****u**Y5422p-3334VWW*BfH2356788 * g.39.1.3 LIM domain
[  56] 11-111---------1---1-1-1---------------------------2--1----1------11 1-1-31------1-12211-11--211111111222-1221112-1-1-----2------111---12111-----------2--1--1111-2------1--122-2------------------1--11---1-22-----1-111111111111111111121--12111211111111111-----11111111111111112112111211112111--------21---------------21111-----------11----------------------------------------------------------1-1-------------22--------1---1---2-1-1-1---------12-11------12221111111111111111111--2-1--2-11-1----2--2---2221111111111111111111111-11111-1---------------1--------------21-11----1-11221232331-13334333232-1---2--2--1--1---1--111---1---------11----1-211---12111--113--1-1--2-12-2-----1-1211-1--------1--1111111111-11111111111111111121211--112-1--1111111-111111111211-1111111111111111111111111111111111111111111111111111-11111111111111-211111----1121--------------------------411---23311---1212---1--11---11111111111111--111111211111--2--------------------1------------------------1-------11-- MLGJWX*-***VaVmIMMIIMLJHJHIIIIIJIJKKJLJKLLMHHHMIJJINLJKIKIIKLJFACABB5AEAABAHD2EDBCCBCBIGGIUIMHIMKJISILGlju8h************************R*********************************s*hr*sv**6ste*KILba****J**ap***** * c.37.1.9 Motor proteins
[  57] 44343499CBCBBDC85A68787HD77B5A4AA78787887685A77657698548355647895167 9HI7S95B66B786LKJCC-CG55DWCBBCBAJOKQHNXXBLJbJFDA6C97JJOCCF34JDJ9HBSRXQA55557443374E66675BBDA4G56-125D8B9ICH9E11111112111111346674464784DCCDD333D9G78B7876788666667885C9AC8465754464755AA876654GBGFFIFJFGHCHFHFHFJGHHGIGHIEEECGCB777877KJ8AAAAAAA9ABBAAAD888AB281AD18121BA66B969579798A3333333444477555553554444444434444344334444A7E3CL55556557687899855484764D7654MJCC9C6876A9A6112E9DGBBB24444ICaSPDAFEFDFGABCDACDCBBK-FGOGGaDRLTA1aMMLMLSTSPRTGKD7AEGOFCGHJHSAAAAAAAAPDDB9A99---12222-1--1211122112213122-9AFNA5DSMESaVUUXYOHJIGVVbYNONNFRaLmJRNJ6DIGGJFEEDKIRMTP9AF7967EC5555555888LIE3IEB89865774464GAG9D9B87BDBDBFA8636846446533534553456559586C8EFABCAHCEDBCCC8EACCCACB9BAEC2149A58332444IGGHAFCKIILKNNLNK-IKIKKLKLHKIKIIJJJJJLNLMKHG8HFIHIGIIIIIHIGHHHGGBFFGJA3CDDDDEDCDDDD22468888777777DIFL888D59245457779FFGDFBE8A9O8NOLNHOOILKHIKDFBG5565545458A8AHCCCDCFDACC99DABAAAAC544444965579BB111111114241-111-112-2-----2-2-112212675566566786A 342466H-O971AACOLQLOIJFXaTQDD9A89BB9AEABBAD9B8GHGLPUcaEFHCFGFI8467652563575B87E8377455443CIAL7EAEDGB9D8CED1GhKjRPGJMOADDFFKFXIDXCy*M-UMZBFDCLEGGDBHEDBHFFOEHJEPDHJEaHDCJ8SLFHK8GEIE*D9ABCaSggJQFJJTPHLL * c.2.1.6 6-phosphogluconate dehydrogenase-like, N-terminal domain
[  58] 88536569888887D858577A64833655J82235543444435344335545DBHEFBC824D125 6AQ7JF7CAAC645CEEA9-GD55BQAAAAA8ABBBAMMO3956C8D97872IE9F8F11ECA7I9NFHI75444655E698L2-521778A17667335C6AGG8AA9-1111111111111543233323334FIIBB111CJ5774675123544423454368753222222222222JBF88BB8DBMLNNNOQRPNRSQQRSgILLHPPPTLHPTaJGMMMMMIlLOJJIHIIKJJJJJJJUJJPOMADADICC9C7BC99GE797CFAA9C8887566C9ABBBBBBBABBB5555555555555A99DB8799B7RGJJLNKLLJLFLF9oGGNFHFDKAHDHB752IE54547P37FKG69EBQ-DDEEB3433354fWc86BIGGKA5789766886L-CBRC9MATGO82gMMRGIKKNRMJPCA78CMMGBGFFNU66666666LDD6636922-22333--222222222222222231339CFA7LTQGPVUUQVVAEFFCQQOLIJII9BaONRSYV24KMFB8QADaFVBVN6C3235287222222254378749G6847A44D767-8683545869987GD685A8438878A62322223224346633D6766AE8ABC8666679J6662E3CA2BE-185A66322444BBYKEBFJMMFJFFFJH-LGIIJHFJHILGHIIJIIISXTLJ8BHABBAA8AAAA9AAAA9JE8CDDDF929BABCAB89ABB222B676778BBA53BIL786B5B47977775C778673546569LLILCOGM6FQHIBLFK222--32-25BDCN9A999HEBBB99779784652323225D55333355565767J-A4-6-2-312241-333-12-13111CECGDFFHBGA8A8 3233BHB-dNB46ABIFRGQPONTMUMEFAEDEFHFEEDECDDBCBKEIMMOZQJJIFCDEFGDH9DK9E99KAH9759CFDDEII567HN9FEIFGDFC869EFF-AFMeKQBBAE8575BD9LGBFAk*91EJG7A78EAAF84E8A3G78HAAABI699JPK6CNBA8BFCE8GJB*988BLRTdnGXOB8HCBDF * c.56.5.4 Bacterial dinuclear zinc exopeptidases
[  59] 331-1-4754454653-312121-B45532731-11112111233225135661-11-2-13461--2 8CD6RA58DDG658NSOBE-DR33LeBBBBBHWVbYPX**AQ8d8A893A65XMUEBE--GIY5IGVQPRD42224541133H22222213413224112A498C5B88----------1111243333424333888A91129478A7877473322244455657785222222222232B8979123EBADDDDD9DEADCCAAAFFDD8CCDEBKJHGA7666665F64666666666666668887742324623222474444131354433444433324433333333333344344444444442244322241456D555656675626774554A65315352288362121125312134C3ALGGB22222F8IDN658CEBDCGHINGEIDIHJ-68E64M7CRUC-PMMONNZWRaUWFFDD6FLYFDDFCMNFEFFFFFFCFD75A7A11121111----1111-1111-11-11119BRfC3ETNFIidgediVOOOJfeilUURQDTza*QgaO25IEHGCECAJGQEOW4581223E73655555263EFA88827446646336-4446547875555EH66323444322212211121114122254DB4AB5O9IEDDDEDDBDEBBBEC9DEEDH-1-6542------FBAA8B9FDDDFDCDHG-DGEHDDDHCGDDGFFEFFEOROCBFG7GEDEFDEEEGCEGEECMBB699AB417898AA97ABAA--1744233999A38GMc454344-11114546QPQMNAI9EBK3POPPPUUYIWWSSDMKL5332243333877D89999CFABDABBCCCA77711111122552222--------233----1---1-12-111-13--122112212121318638 --34CEE-JB81EHBKNRQWRUNYbWaFFEEFEGHGIGGFFGGEEFIFPZao*yQPKFEFJJIBE7DC7EBAFBCEB6BAACBADG78APfTNHMJHFGADMKGDG-AXEqXqVZVWKJKDKNLWYIiI**U-YVoHIKFXKJYICKIHHLHDfGMKJUOjcGfNPKgFJOEVXF8DC6*878BEXOnlSR*EBbLdSO * c.82.1.1 ALDH-like
[  60] ------------------------22212113111---1211122121-2224-------------11 1111113111121211133-31111233233111122111111---11111-111111111111-1211--11111111111-11111111112211--111111112111111111111111111213111211111--111211311112--1111111121112322111112221111111--1111111111111111111111M11111111112111111111-11111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111112211111111111111111111111111112211111111111111111-111213112111111211111111111111111-1121111121111111111121111111111212211112222222211111111111---------11111111111112121111111111111111111111111211111-111111111211121122111112211111211111111112111111221111112211122121121111112311111111111111132221232111111111111111121221121211211121112--11111------11111111222112111-2111112122211111111111211222111111211111111111121211-111111111111--11111111111111111111111121-11221111111111121121111112121211111111111111112-111112121111212111211111-1122111111111111111111---111111111111111111111111111111111 B7CFhhe-uOI-DBSBEECEDDCDHBEDBAC9B9DDECAB9BBCCDDAHGLJLP9EIFCFFG9ACC9D2A8ACC9DC9EEBAEDCBEAHJTLELIJFFGG979RST2*tt**********************d************u*************q******c*hW*s**d5NQE*GEBJE****D*zJBm*q** * b.7.1.1 PLC-like (P variant)
[  61] 44214353334344331233432272264341122231----1322-5559992121----3111123 6CW29331331-3246733-371164333336678758A9-93B232-3---324--1--3555C326CE3-5331221-281122--5563-445---69676A7A44--------------225443612696GGFKJ---O3A35933922------1-6632C86C1-1-11111--15542244334644444335343433323446434345343--------H7111111111111111111111-1------------1----12-1-1212-------2----1--2------1-12111-1211-------54534222222232322445334345216-311764324-133---3-2272X233-11111258DA4237557611111111113-999A97996B4462244467775643547A759889B491111111122315665--------------11--1-----------2111-332252224224-22233542322215597464--444452216A7294-1456552211------1163-BE713-45352223153513215834B4QZ251-1-------1-11-1-11142134657844775275757776566CA96687E658--13425------26222425445554A45-4344545453454445445154341133222323223243223243333231-377667767666---6-----3334B2E23------------3-3------4-11465545585574743273521222212145BA655565478774434344222----111977558844454454631-----------1------1------18--2111212473 AB22QQW-C113448667477588773994668BCB4B9A59894624399AGH68574777332112-21132222-22355321-22EAA697G6555476543-H*w**********************8************s***v***************TADBDO***Q2H95b57694DKIE8JB9DB868B * c.62.1.1 Integrin A (or I) domain
[  62] 11---1-1111111111-2--11-9334-53211211-4232347212--C55-----1--------- BDJ4*87899A675*ywYY-YvAA**XZXXVg*w*w****5zN*TOC99GA5HJHF4P--XbP9*T****J24552442465A52443A9B51733---3I558mBMAG---------1----123-341324517A99E111W3R6BD8981411111-212619B9K5-121--21-11-839443239AYRSRSSOTVBQSQOMQLEMLHPRNQ7AEID46555455nV4433333433333333337373439833433664367662632688111112155422221222222111111111211131244422214CAFF7769767776G9FG355492521A3261NJ955688653465423B3HlJJH--1--PIlNVD57WHKLE6666656656G-CCIADLCA7aQ-WMMKRRHXYZJOLO7F88GEB6ABBGG888888887CD458CA-----------------------------14IEA24MGEOdeiceiLNNPMSSWWPPQPCXnKgRXUW13KIGB9E99RDOHRH5I58CAAD433322225359886qKP83894AE8891495D99E8A8BB8Wj6B3111-22211313-11-1113235822EB6AKCO7J77DDEDC9DCFDECDD9BCDE--11652------BDBB7E9BA9ECFEFCC-ADCDDDDBEFAECCDBCCCIOLBB9AC99899B9999999899EBC8AACC7-976888757888--172222235364EP9G422113123322223LLNKNDC664A8TTRTGbSWJKKIGBWST1--------399AGABACBCCDAAEL9FAFE7563232--62EE89881112112-1141111---------111---------22332343331H23 EBBCkv3-M962FJ478IAABHEOIKNCGBDDFMGCCHJHJDCEEJFH8EBDLYCAJNCC694281241733315763834456A3311AI8879F31-424179B-4hUQBAjOFMEHLGG6HGEJJNn*81SEXGOPLBTEEBO9JNJ9ZNIXAA9*BCQDE7TNC32PKFC32FI7NH36D6OC8TC7A7EDGBAE * a.121.1.1 Tetracyclin repressor-like, C-terminal domain
[  63] KK5GCLRCHGFGFGGM88KGLJIFJDDGAGJHFCOHJIKLKKKNRFPKHMLNNFBBABABCAA9926G 6A82E64BBBB5878AACC-CD33DBCCCCC7FGGGCACB8BAEA984B885BAA68811EEB6AEJKSLC32223545374C67B9A886729341--6C78CB48C955555554445555599877989789FGGHI4457AQFIHCDCA8CC877666E98ANNKE464434594455656CB4436BECCCCCCCDDCDCDCDBAFEBFCCD9DBBFCAA99AAAEA9666556666666656677794448843534543388844453544777544456644445444445444444444444484444344462GDBHBBBDCDDBB969IICBBB98775954ECHJGK7B8EAA65622558ABB99A555558AJDEEA9CCAB99989999889D-BEH99J8ADGA5JFFDGEJJFDIKBB898A6GA8AA779666666669CC65ICD33433333333334344333343344544266A85A9989JEFEFHEBAA9HHFLDDDD6DGIFBHBG57DDAB7ECDEBAHE89CHDBABID4454544898FDH8LNIEJQH9SLIFF5BD9B9AAB7MLRNHN8K642243322341311111126743677GG6CDADACFCGFGGGAKIEDDGHFGCGFK1-6DNDC221333FA887CABCBCBCBBBA-ABABDBDBDBACECBBCCBDDD899A9BCBBAABAAABABABACB9AAAAB63B999999A8999344855545887A8AIFD3333443333225557777778879A8GFGGCADCDEDDEAA9A776757757CEHFEFFFFGGKHGHBA9AABA898544476H67777BB3334334365411111-2112211222-1112222266766B7BAB3B84 1311bbP-TEA8FGTADFEDBCCEBBCBABBCBBB9DCBC9DGAABAABBCEEGACCAEBCBBAAAC73B95C9DDC8CC8AADFD789BJCDICGC9BA9ECQSU-KaMTWXNaQSHJFIELDgYFOG**T2RNeBFFCRFGHH9HJB7RBCPHSDHIGNPMKDH8f8FMUaFCEMQP*HFHIK*gt*CifIMRZYcG * d.37.1.1 CBS-domain pair
[  64] --------1211-22--1----------------------------1--------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2------------------------------------------------------------------------------ 6646DAI-Q959B9KGFIFKHFEGIAFGJCFFKDCBAD9DBADEGEEHDDCEH8CDEAFFCECAI9AB9BHHCEBJIBCG9DFCDBDA9GPSFCLJBB9DBPARcU3AD7**********************S**************************************PizQA797V765CEVrl*D*Q89EFCB3 * g.37.1.4 HkH motif-containing C2H2 finger
[  65] 333221ADIHHIHKID2955453-G44494A3321---------521-1-653-11121116442-56 CBN7i84CCCE333JNMGH-HW77YoGEGGGKRaabVg*x6SHeXFH97GA6MJPDAD11HGMBiBkicSC31112422--4I111111132-2------9-81Q3C55--------------3432324332447AAB7111E9C548442--12---22--13CAAF61----1------67566661D2EAABAB7AD2AB9899D8779A7775314CB77888877E3898888889998897778A4-9-8D-B--1EF5568B4555C5453231222555444444445452222222222222422231222354118332533543375111-1-1-21-211--212141221254441-593GLDDD11111HFRLS83AJHCHF5678677566D-HHHEHMDGAMJ-MOOIVSPQTZPSDK7I8DBGCBFEF8H66666666BDC6389C112--11111---------------1-1137NH832966CRQRSRRNMKMJSSQUPOOP7JTLWFVPI-19AK5C6CAG9EAIE589-534723232233426B6554711-1-132----A88234333DEJILQ364----111111212211112----234553B8676N863644648464425345363--15643------AE7A48EIHHKIJJKHI-GIGGJFIGFIGIHIIGIIBIKEEE753CDEADCFDCFDACAACLA8ACCCE1-755555555555---5221226555367KD222712-111--23-6698C475A6K3JKNJAKIIBGHIGDHIJ211212111-54473332358667BBDBDBA7A8B555--27775567--------1--------31--1---11--32-----23111243436753 -155itC-H73-25Ksu*nzn*m****QQOMJKMIINLLKINMIMHvdh*u***nwjeQROPIHU8GEEHBGQAPIJFKKDNNNILCBAm*VuRfOTPOGSCOKHO-AnU*ED8FGDBCACDB8OK8SBk*G2QHVFDB9FBBOA8BA8B8FCECM9FKFNA5NIGIBCNE8B9IAEI8p766GJVdr*gcjBCslijH * b.35.1.2 Alcohol dehydrogenase-like, N-terminal domain
[  66] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----11N-313-142222212132222111222222211111122222121-2-11112111122212221221211-11111121212-2222222222112222-232**********************A******************************************211-5-1-12442523--12335- * g.12.1.1 LDL receptor-like module
[  67] --11---1222222111111-11-122112-1--1---------1-1---111-----------1-13 448-51-----2---1-11-1---112112---11111312533221-1112--11-1--11111133332-111---1111412222445622112--1111253351111111111111111111-1-2124-333672222362552243255222441334655352212143322231431122-213222223222222224315443223221122221111222222222222222222322221112111211111221111111211111111211111111111111111111111111111111111111-112111111111112122-1112-2134-221233321113322211-1216122522112555665424434322222222223-44444335143-5332563655442113331244441234444444423342343111-----11--1122111111111-----424124333233343443333665533333355644333253543242344332344343223112222223357323121133233332133334224155545724112-111112-111111112222-233111224-31-13333343333321223224--13323-------1--------------------------------------1-----1-------------------------11111111111-1-311111222232313122--21--11-11-212221232232332221-3321232232---------21--1111111111143434333441111--213322221113123323--------------------------12111111116332 51-122*1922-1143111232312122322221231111111222-114132413-1-1-1-1-1232221312331221121133-11211-11-----21323-Gs-**********************a**************************y*****nr****n**o6B68wB7584B8CI-9EXhdrpsO * b.36.1.1 PDZ domain
[  68] ---------------------------------------------------1---------------- ---------------------------------1-2----------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4-------------------------------------------------------1----------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------2 ----314---1--12-----------------------------------1-----------------------1--------------------------------7i-**********************T*********************************e********-11------2--2-11----3--1 * b.23.1.1 Spermadhesin, CUB domain
[  69] 33444355666655774764575A797756676596556655568476678A8644333437445-33 87B3E648998857IDDAA-AK55FOA9AAAANIIJIOjZ3D798465555468886D1176H7C6IFCB86555776328594435388884D331--48486M89561111111111111127559995558799978222B3IBB799B55885555448B46FFBA444655544547A896566277CAAAAAABA9AAAAAA7888BBAAC7898C878999A9GC599999A9AA999A9A87A97664AB4443678449984458685544463444556666556666655555555555666664446665679BDAAAABBC8B98BHH4675C6434877K7EBAA985F6888A6446C7AHAAA23333BAHFH867A89B88888888886A-99B98D8CBEG3ICCBDECEFFGGFEBB9ADG8988EEICCCCCCCC8A889C683353233343112222222122223334379EP759HDAHIJMJOOFFFFEGGMLHGGH8IQEPEHMD58FDHC9ABBJEFHFDA8A6788EA88776775558D8ALFCD9865AA88936869B7CD976678C67658534445433333333335444744CAABF6H8CB9BEGGE9FFBBBCCDDCCDE1-466461-11119ABB8BBBEECBDCCBB-DBBBCBCBDBDCDBBBBBCCDCDBCD8BBBCBBBBCACBCBCCC799AAA921988999988999--253433379A979ADC666769545546445FFEEG9FCBDHALLKLKIHOGMKJIEIEJ64666666478ABDABAA9CFF88BDA9A9988854443276DD67AA33333343823----1-1121---111122-1--1-27847656567754 4556HIG-TF86DDDTXTSZRTLjfkWFFEEEEEDDDECDFDCFGFQORYbm*rQSKIIJMJHJH9DE7JDFLBMEB89CHIIIGJ8FAL*SXMcOKHIFDHHQZS3CeQqAHAACC88968D9DA9M9e*I-KJN998CCB9KA7BC98B58C9DH9EEHPDXCDIJAENIPSB5HHG*DEECFdVjjObTMJkZo*Q * c.1.4.1 FMN-linked oxidoreductases
[  70] A81121635444454534546341B6688B98--1111112111214322333-13125546643167 DHZ8I777AA9543DCBCC-CF55HCCCCCCDE8AACBHF4D7G76855644BFE66922AFD5B9CDC97-2222223445896989KPIN-ECB2--AQBFCzJMFZ222222222222225887785777H5DDDBA222CBEACCAA999996667679A9FDGD8675766676766A7A774328BA9A9AA8AAA9AA99ABDCBBCB9A9CEC99A333333GD75555555555555556545313-33-31-22211441113313332224333633444444444443333333333333422221222228458333333323426331755B5364C13213341-422-13341366F3REAAE65555BDJKHFCC9AABC6666666566A-CBGBDFABACB3C88CJJIGJGDEBFABBGAB96999BF888888888EC9ADBB666555554447554525564455344446AERB3CJIDJKJJLLKEGHHGIINTIHIIGJMITHQNM89MMLNG9DCEEICJ9BILFDDFDA7788888CFIFFME797588A3876582B7B88A867EECCKa86678777777884445444446936856DE6FHHKAJF8HGIGGCICHGGGEECGFFH112DC9C211111A87758888878A6977-8799776767876778875BAA89567A9899BAAAA9AC9999888888851A88888778888223F454447787DEL9A77767559889744755565475A7BEFFHFJHKIBMNNJGEBC523334232A8B9A99999DCFA9JIEEEEECCD67576775HHDDEE--1--1--423------211111-111213-1111142335433436D5B C922IBI-pOI699EFFOIRKOISLQMDEBCBCCAC8DCDACDCBCHHFMILRO9BGEEKEFABD8A87DCBCBEAB9DCAGGGEJ668GdFFFKBAABCADCHGJ28kHpWeUTONKJHHNKPiZDPHv*c3XPiFHKNPHQVKFOHJJLHHNMKKLQBFGELOOANBDJMWZFDOJF*7CCMKYVd*NaTKIWTUNH * c.47.1.10 Glutathione peroxidase-like
[  71] 33334334333333333343443463343332544323345543333455454645334444354343 ---1-112111--12--11-11---111111-111111-11---121-3---21111211-11212222121111---11-12-111-22-111--112---1-111111------1-12222112121111321--1--1111---1--1112--111121-1-1----11-1111111-1211--11-1-----------------1----------1-1---------1----------------------1----------------1----------------------------------------1---------1----111-11----21-------1-121--1-111-1--112--1111--1-211--1-211-1------1-2-----------------1-1------11----------11---------------------22----1111-----11--11--211112111------11--------------------------------1-------2------------1--1--1------------141---1---11111--11--2-1111111-111111111111111221122222-11--1-111-111111111111111111111111---111-111111111221-1111111111-1111111111111111111111--1111111--1---11111111111112-1111111111111-1-1-----1111-11--111-1-111111111----------1-1111---------1-1--11111111-1111-----111121-131211111-------------11111111--11-121---1--11----1----22211-111-121-1-- IHEE99e1W886NQPRQOPQRRPQNPPUUUYOVVUXSTNSOSSORSRQNQQRQQPUTSTPSPPKKMML8KMOJHKKMEJMNLLJLLQPJNXLQNOONMNNSMMZVa9QvE**********************9****************y**x******n***pk*j*zy***yk8OWp*dfdPQVo**S*YBSJPPQP * d.51.1.1 Eukaryotic type KH-domain (KH-domain type I)
[  72] ---------------------------------1----------------76------1--1------ ----1---------------------------------------------------------------------------11------1141-3-----316-112--1--------------4--------12---------1----1--1----------------1------------------------------11-----------1-----------1224-------------------------1----------1-----1----------1212---1--1111111-1111112111111--------------1-------1-1-1--2---2---1--1----1--1-------------1-11-----1--2---------2-----------------------------2------------------------------------1-----------------------------------------11-1-1-------------------------1-----------------------------------1------1------------------1---------------2----------------1-1---1-1--1--1---------1-------------------------------1------1---1---------2---------------------------------------------------------------------------------------2-1-----3-15-22331--1-------------1------------1---------------1133FA--------5-1----------2-----------------1---------- 11--FFP-D78276D522-32335231222122423211-11112422344442342442434132-1--2233412-222EB4371--673276542723437471*ca**********************Y**************************s***********Zbax-JBA*554I4X*l*-qO4ANTFUE * c.10.2.7 Ngr ectodomain-like
[  73] 11-1-2111111-1--121----11--1-----1----1-----24-3--321-1-2----1--1-1- DNY6Z989999989LIJMM-MO99OVMMMMMHQQPRORUR7F9CGGCB7EA8DC934F44GJ88NCOcaO964554546697A44433DC9938555--ALBERNDP7M333333334333335665566557669AAGG-1-BELACG9A96777587767AA79CFID357444454454B9967736CBIbbhbhjgnTncfhjfNFLLHIgjnGCBHH89BAA99AfOA8A9A87667AA86979BA6CCD9FF99DCBEC99GFA7D77D988BBBBAAAAAA98898888998BCCCBCBBCDC9CM99EDA888A6HCEDAAABEDCHBDFCGGADDDGAB97LCC78GFDEBB7E89CBE8367R84UKKP46666CFPQOCC8GGFGGCCCECBCABCI-FGJFGLFFEIF5JJJFFGEHHIIMCDCLRADAA89B8BD6666666699A99A8C33111111--33789969A76688732324FEFLA9BB9GKKLNOLHHIIHIIFFKKLK9JSFCFJKG55GFF88CABJA9DL9BB88A69C744444444799ADD9B9646578877629A9A87A89ACABKJ7C5443544343534343353344433BBCD7BBBAAG9ACEEECFBADDEDED9DEEA1-5575812-222HEB9CEDFGGGFFGFGF-EGHGFEFGEFEFHCFFFFEIHF9BIGBEFEDEFEFFEECFBDFIDCEDBCE74E9AAABAAAAAA335G67666DHEC9AG88978757687756767FDGFFBB8B8BBIHJHDHCFCEDDFCGEG44444444477A8GAAABAAC8D8LKC9A9A99787773267IIBBBB44444445742----2---1-1------2-------34343233225B99 1211A95-D4344359EHAC8D9MEHE777756B87987999A56784DNKKhOA8AD5677527132-3231-612-11222221212394E464211312628216XCn477AB7452537396384IiA-A6F41-353484544349237329576777LA76446-CLC34353D3321AJ22EA9851D5379 * e.3.1.1 beta-Lactamase/D-ala carboxypeptidase
[  74] 22222332333333322322322223525463233332445433332415243121212222344123 225778A888989877777-775567777776998959DB787A674576677C6564338865B68799866668765443343645776528771116A8798567644444444454545564354755458555654368684864544555644644463486A44544445443467645533296688888989777888867667678A5785578888987875566765577665675556576578976766666676585555566586556544565555665756556676555666654355333362956A7778877B7969776888557547855576454255344443223755A7756555656C789565755788888888889188B8EA9876779887785BBB878986567978697866666666668655C87775444443322443334634334355556555556555599A99C75555888867665689997C948877B9676AC89A767B6545974555556555A8C7694634444466634446565667887CD56742333444253344333336464677AABDEAAADBDACCCD9BBBBBDCBBCBBA416697A555445AA988B9CGFBCBADDB-HDBCCCDCBCHDDCCCDCAA9A99979BABCCBCBECEDECCEAAB8BBCA74B999A99898AA668666566455597HAC777877777877AB899B9A887979ABEBBCBBECDDBBBBCB666666666ACFDDBBBCBEFEED9877887989998966C37778771111211133522224-323322222233422233346444444444657 ED47MUJ-*PI7DFIKOQMFHJIJIFKGGIIIJGGEGHFGGFFFCEGJLLIJKJFIKLGGIHEGGEDF8FDAFAFHE7DGDEFHFEFDFOSGOOJdGEFGAIELLJ5LuYkVYOVpbROONMUO*lLpO**d3jd*GOLMjOQbLHPLNKcNHhNVONVUUbIjfoGbMUMQaYODRZM*KKMSSjcWhOsPNLNJKZL * c.55.3.5 DnaQ-like 3'-5' exonuclease
[  75] 22------134211---4211212----1------1--------1-1---2-----2131--1--2-- 7DV-7-2-------35422-23446222222222222322266722252222432222--AD227666666-----1-3344244444AFEB2C776--8G4KCEAJ8Q888888877888888666666667J6766AB22276FEBACCB4488444444AA8CEEKC4444655444447BC4423-66678788778867777787666A7798676766444444966444444444444444446543344434334444544423533544444468633344444444444444444444444453445444436EBD8AAAAAAB7A6A6EEC9896B644A462233232246226667222O6B9DD92222266C6A6766666644462266247-97B6766676626224256775226764C776666676666666666266626A66666666666-122223243222226678-E96AA44444111--11------1----2----2888A445442664474444444844545433-----445544AB986A8C8B8CC88B9C8988DAPQEUVM8F578584454444444444444454432CC4G88IC8G4KKLLJCCDJJJGGEFIHFH--18444------88696789999999999-999999699A999999999888AB6695555555555655556699676694-B87778878777--3C44444454545C6E66642-433444444777777C999AG999999886DDEC788844665444478BBGDEDDEDCFCC455555555544544-B3666666877898885341-1-1---------------1----22362333245E8D IHk*NVJ-*LNBLJLLIMLINLILQJKKKJIIJLLMMJKJIKJKNPKMLMLLNwJJLQIKJKOOQPOPNNNORLPNPGLPONPMOZIKJLdFIGFIEFEFNLHVbT7V*kppmYdgaNMLKPRGimLvK**W5ZakENQORNPaIINROFRNInOeTRSNfiVVNVWeTdyOzdKRMZN*RPPRTvbkjKqkadQXUSS * d.185.1.1 MPP-like
[  76] 55524299KHFL8IE8AFAA7A7BC7789E553A9457674455B2KD98KOO26E469C77573252 BHZERA6977C665ADF88-8H55CC788879HGFFDCHGFVTVSBHA7GH6EAEFH622JIC9MDFLEJB34443231232DB627ANNPM4T772--CKBHBTLKDI112222111111115BCEEG9DFHIAlnn*y444kEiRUqYWO8BDDEJA9GEINFSfmjP89AAA86DCB888B76A7B4946A8B8C879878AA777CAA6977G896658A122112AS655656766655566B876513247A35337DF669D2D67647535555333322657556653452111121121112766756666596-KC989898869772778H7693D44D599897F8E4B66C547A433D5UCBDD21111ELRKIC58AFAFI32663565559-PPiURcWZCH71KHHCHJOHMFLNJAB656E9EAFF6A7EEDEDDDDSMLLEJIQ11--111---112122422324224---167EM56BJJEFQIJMNPIHHHHIIWgLLLLEMOLeK8DA158B3CC99628C9C356DF868865633334CDHKKJ3NHFBHQSBUFMMKBGKLJLDSEJOKPQNQLM8ABD9433344111111111A9579KH774GK9A3G3A3676744556444765233--2MBCD------47778876677669474-666687787764766666878745BA5A789999AA799A998A66465548-4222222222221121344334655K6OEA463715-234423248535668546IDGGEGAEG98GDAD8BDC789789888799C755455C968B58ECDCCBBBAAAA11T5CC66AA111111117-3--11-----11-----1----1---B99CA8AC98FcHM 135569D-D66278768556A88BAA833563334532534344457535856866584666532263-331434342232431437782C48643535A69688A1DZ5*8C87775524476DF485EiA-55F4346A435555344436B2666477976467755B23C59RJK*JFFMJbWrk5TLAAIKGUK * c.87.1.8 Glycosyl transferases group 1
[  77] 114-13333222333422-2211-844854452322241342231335149A522222224233-222 -263N113333426KLE67-6G22EH66666AHHLJGCJM3RASBP94275154353511BBB3K7GJIM4333343322473--121--22-3-2----124563351---------------2322132222368865111C2A8A98886755647876AA66CBB955655447455456623--4627HGHFGEIK8FBGHHCA84465JGH7876974212222EF332222222333224234423121222311233223312--11343121122321122242222223111111111111132222222213536555566677662166477685641143324431-425222122-51227D8882322365BEF7548688866676676648-CB8AACAA5GC2D779A8AFA9AD7C4A4B5464665683333333333453776111111111112232213312212111123A6C9573334988A9AA666688A776664899959B8347756958689BA88468764774333333355967486974452-5322--4445426523443CJ242--------1----------32-14554578A8769C7766667B886656888596--25666------56655565554544465-545575544555644644398678344543446456456444784445556415555655667661125344359H9B5BD77322331211122332A7A9B6967764AABB8A9A67A9A8A8E211111111687894447478755A97595876633334145667766--------221----1-2312211222212122111-11---2----142 DA58JVY-bDECEEEPbgLMLKTmegk**x***w*z**t****LUNNTNUacszPbQcpJFK99k6768DBAEAB9A87B8CC7CE999s*ob**zDBBGEMAFFF3S*s*GRTSSjMOOESGOYRPXQ**K1UJbJRSNJPINQ9JMILJLSbOKMFQGJJEPHYK*YtfXyNFEkcU*WVVKa*sa*Rn*YTKKJGt * d.144.1.6 APH phosphotransferases
[  78] 11--------11-----------1--------------------------11-----1---------- 6GG-B213333122354AA-A522D5AAAAA7455524432859332341--212241--5361B26774111111112332622523ABC71B33---5S575pJI1C11111111111111-12-211111A1HFFDE1-1E1RMHMDD866FF8375869F6FKKWA17331216141156455211-33444446543546764-44422568-353-25DGGED9932111111112111121211-324211232-13322113233212242223111121-----------23223223323321211112223144486668678766354427755531411255JN444431312232-11144955F-----3CVOSBA6JGKIH7777677775B-NTPPKXIT8A6-989AJE9GOCCF89243G96AB99F6B2222222252221VAA------------------------------47D6-45524CCC8CA5768799HF9999588BMDIKB24AB7FC8ABEFJEJ565F4387631111111238C9FFSE6C5454BB553-44554325378F8MN3851121111112-3-------54433557825A96466646556445544779478A61--3C49------64223224444444444-4444443444444334434364334424545344334454554233343442-233333333333--14-1-1256661AD5822222223322333322222131115967676898A64667655---------45989888888B8BA44334442211111--GJVVCCEE--------B52---------------------2---44132111111319 8C8ABCJ-*TP5QNa99A69A9BBBB9887A89999999A9999CA7999C9AD979899998889A774628787838867877676689697888788787FFJ3H*A*******iYcdcmi*zg*f***3*t*XfgX*YiveXkhZWwaV*gyejqhx*yw*YY*cc*boxa2gpc*JOHLIOQLf9ZJIj***** * b.82.3.2 cAMP-binding domain
[  79] 222-3445666666642-111--25223113411111111111111-111111-22233322221-11 9EI8L786776996BBA9A-9855CB99999ACCCC9DLL8CA987796664FAEA9955BAD6AAL8C7A3222222-223B97596BBB81A553227DACAF9E98666666666655555547875578A8CEEEC1117BD88A6684388744577966DDHN635333436333366755334B79AAAAAAAA8AA9AAA8CAA9AABB8AA7A76666666B5688888888888888788977-417814-1-773356543232343444644436633333233333666666666446544433344443A74B4444445554367723323311592661A947754B368894434B4DJEDE77788BGUPWJFFHKIIJFFEFFFDCDEH-GFKGFKFCDHE5NLLJIFNJILEFGMCDDFBLAE9AFFHFEFFFFFFBCDA8DEC4444444444224433445444444444468HIA7AIHADIGGEFKFECDCCCFIHHGH8HDIHKOML68IJIFFCIJLHILKJ88M8D8BGG7788878CBCGDJ77C37AA7986558-EEEEECE8GLLIJHA456412222232213111111133464AAGFILJHLGKGBKHGIGIGJMFIGNMONINQ1-98D9B2223339BCF8DAABBCACDE9A-AB9BBBBAABADAAAAAAGGKEDCEDDCDCBDCDCDDBBCBBBDA9B999B84CBAABBAABABA334G77778DDEFDIODE8A9888766665788DDEGDABB9DHHTUVVGRLJRIIFFCKJHA97779979BBCDHCEEEEIGEHIFGDCDCD9AA889865847777431111112141411112-1-22211111231121---22232323234B67 6811BEA-M97188A6997A998A9B99999686778988888A99B99CCDDC7A988877A879886787777AA6AA9678776768D89A9B8997A8ADBE-8QJHCFDIFE89BCADAGHAQ7c*K-NFR9787C8BOE8BB79FB8G9KB9FEMbBN9D9LACLFCFBCEDA*997DEKFPVAQDDGLFCEB * b.84.1.1 Biotinyl/lipoyl-carrier proteins and domains
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kLG5GHFFFCCCFFGEGEDFFCEEEDEEEDBCDBCFEFDDDDDCCCCCDBEDDDFDECDC7CEBEBCAE3ADADEDECFHHFHEFCFFABAADCBGKP5GLZgIPIKKGABHCDIDORBWDj*K3OQWCIFAoBEPGAHCFBME6QDOGDJHTvFHGHDUHGmUJGFIFII*KHIFKeRzoDYSJKLOFID * b.43.3.1 Elongation factors
[  81] ---1------------1------------------1-----------1-------------------- -------1----1--1113-3111-133333-1---1---11------------------12--1111-----------------1---11--1------1---2-----------------------------------------2-------------------1111-----------------1----1--------1---1111111111--1-1----111111---111111111111-1------------------------------1---------1------------------------2------------1---------------------1----1-------------------1----------------------------------1-------------1------------------1--------------------1-------------1-----------------------2-1---1-----------11--------1-----------1--1--1----1-2------------1-1------------1--------1---------------------11---------------------1---------------1-------------------------------1-------------1----------------1-1-----------------1--------------------1----------11----------1------------------------------1------------------1---11111-11------------------12--------------------------------------1------1---------- KIIJ**O-*cXHPPaXNPKLLNLKIGLMLHLIJKJOGKSNMKKKNNPOMMOLQQKMMKIJLLOGJFJH6DKGKDCIKBIHKEGEBGNNOShVNZTgSONMMYNili9Z**********mywu*y**i*****6***g*xn*s***j*mrn*ll******c**w**xj*l**aw*nDvfY*SPOda****L**MVj*orp * d.15.1.1 Ubiquitin-related
[  82] 559E6AECIKKHJJHFGAFEEDER83353838aIaSQfgaVXbILGHTEPdWYNEDBOGJI677E133 9FP8723222231348977-79228A777775ABDC66C664643453411113321111A98B8797A6422223225J**87CD8A89GE4C552224554597745111111111111113DDFGABBCFCCBAAA9QFJ69777866544665444346645C78545423327332455466FB65345566574656556652-66266563372-114444443543333333333333342232611----21112212---1111-22222211111111111111111111111111111111111111111IYSEPMMLMMMNIMJGRTSBB99NEK98M96LU**daXKKbYgEDHO844AO6433933333ADG9DB89BFBCB55665766668-B9C9AD8E894255546787759699367E899A9AA8C66666666D7724N6B22323222223333333333333333333635B517995FDBBDBE99889BBCHCCCC7DECEFIJC49HHCMI6ED9FBPF89BDH8856D3333333257RJL5**kWgjdYpcccf4abYgYWaPSPNOQ7HWy9IDEC778867494444354CO9EC77QI825472353BEGFF3CSHFGFFFMHHXI4-15JBB443555MELFNG3RSSPRQPORR-RRQSQPPRRQSPSPRRRRLGHGGD66KSPPRSQRQRQQPQORQEJLINMOO41EAAAAAA9AAAB3345343344556B2682778A883875864496666645545939A78689548678957775444654557AAH767769989B774454433333337AG98888771111111192211111---11-1-111-111-1---7A88ACAD9A7J74 --127BC-723*43443223222332543332234342233232432233454333333223323----3-1233------232331--44335252222322236-5COJ3E98712556552EB494I*8299H6345C45783453463464964758F7G74693926F815675k35264858I3533392344 * d.58.1.5 Ferredoxin domains from multidomain proteins
[  83] ---1--------1-----------1--21--12--21-212---2--122G231-1121-13----22 1-1-2-1----111-11-----11-1------------1------1------------------3-1132-----21--21--------11--1-----14241312-3-111111--1---------23-1-2-2--2----2-3363331--1-1-1211--1-313--1---1-1-----------1---2222222343422231-11--32411-1-1344233311---2-1--1111--1-11114--1--1--2111-----1-1--1111--112---------1-1--1111-1-1---1-1-11-1-2-1118127111443224212331211232-1142-11131-1--1-2311-21-184442-2---13312--11123211111111111-13213313321-311424163352-152465-3133255111111111-1-1231---------1-------13-1-1-----2-23521111-111111211111111122212111-2242--113-1322232-------21711---------211124812-13-543361-1-521212----35-5-4123131131--1------233----1-24133-5A2-1211121121211-5113--11---------------------------------1-----------1---2-11---------1-1-------------112--------------2-11---11---611---1--------2--33--31--1--31-21132--1111-11--11-11111-11-111111-1---56435324432222--N6--1311-------1--1131---41------------5---11--1----1--111 QNLMlmt-*XeEKJRBAFC6CA7D8B75565769A76655646766CCACCAAC88DBBAAAB7B7C66D7B7FBDD79B7AAE8D773DGAABCE9A8A8I6WTL4R**********psp**q**q*z***C***l*vv*****k*rjd*ui*z**********ob*fw*q***6****UVRTQ****I**eq***** * a.39.1.9 Cbp40 (plasmodial specific CaII-binding protein LAV1-2)
[  84] 11312--233333347354364214--5426-1211--1---1---411-443-1613531521--1- HLM2W5A98886715DCBB-BD33BA999998AFGGD9DE7CBCNLK6FDE7JKL87A--44B8O3EQQJ8KFFFEHF6-137211--LLNJ4B55---7G167I6NBC34444443333333659457847777MNMFE---M6AJN7DE5663356866676298BH7444544454544JEB453523969999989979B9AA96BBB2B99A67816FE5887862Q733232323333332211326B3-6A22548CC5579262DE6A86666CCACBEF9AAAABBA9A97555677786555EDC551DCC7AF-4D3433633G4CG6552CDAA-3B617M63551341C4-7454A23722B8663-3---38BBBB76BCCAA----------2-CCF9CFBEB69-777EIG9IGGAA73833454ADBB74355555555766-73GB----------11--21-----1--------64-311776AFCC6CFD6899AACH788874DDB887---668A-B--14-AD1--A78271---1121-23988234552847254334-B9B49862ADDHDEL5B1-------------2------111144CCAC6I61I4C7878959-877367273-6---9333------8E385868AA898899A-7A88A88A98788688777CCB97331A96AABABBA8ACAAAB67577973-978887776777-----1---69566-D39333686-34244454232221----BM77A7798CC8998DB9953333343345A9C67686BBBEFA3JILKKCCD1121--625511222222121141B-11-1-111-4-122251--61---99D6695A9AAS79 2-56LGV-SA7BA8GNKaOOPTTXVXfEDBAAC698BA6A7D9G98MKGHNSTcQUHLKCED467367436383BH96QH4764AACFFORLKGVKFBDC6a95CA-GZHyTjdeYdSNHNHPRnmFlJ**u4rW*EHHEXIRjRJMHHLbFEfLUKMaLbeRkOSUVUceHOO8CPVO*JIKYXemtxNmf7B759AJ * c.1.8.1 Amylase, catalytic domain
[  85] -------------------------------------------------------------------- 9IM7t466778555EFGFF-FK44FGEFEEECNHKJHLON9SLXDD789BB9FKM56A11aRS6nAWcYhB44447666AKF724366BC67-922---2B444F4B7B11111111111111142322248242ONORRI8FR5OELCED888AB868A99AB7CIIN6574554564544GI98823-A5GUUVUVSTVIVSWWURGIECBDUVc7ACV7DDB99A9AiZ799898988899998899A6F675CC655466677CC655675686DED9779999888888988886555566668656A8866487885TKNZQQQVUUVSSKEfUU8CEARKE9BBGQ72hcF99536645476248G54FCCD76666DFZLNE8CDKDFIAAAAAAAA99C-GIKFKOJLAV92NMMLLIQVSMKJGL9C9CDFGCGGACBBBBBBBBBDCC9AIDA1111111111223233232222332111146DF56GLKFMUXaWeTOKKKERRUWNNNNCNaTVMPSZ12JPRIBKDCYHDFT5GLG8868B91211111753BGIB7933331464334-C88888A978777BC16VAB87666666333433333LJ8CNA9LG9BDEP7GD9OGNNJHKMNLLMMQNUNQW--23336------GGDFFFKHJJGHHHHHH-JKIHHEFHJJJFJFFHFFHMKLDGBBAKILKKMMLJMKJMJKJPDCCFFFEA2HIIHJIIGGJJJ115D3333345447BNBK444333243333125CB9AC6A669EBOMPONTaWFPRSSFJKM3212132224FONSGGGGGLNUHJOPFDHDEGGG6545--B1445555--------1-2----------------1-1------37634444445D32 -----21------1---1--11-1-1-1--------1------------------1-------------------1-----------------------1-----------2---2--1--------11251--11-1--1-------1-------111----1-21-1---12-1------------B-----C---- * a.4.6.1 PhoB-like
[  86] 222222322222222211-11113CAB889A9676676666675987568AAA244576844444255 6243854365734333433-33113333333333332457533524547312445332324363314232322224322254211111531222112--3727331524111111111111112223233222224445612173934433333443333335436544433333333333325322221446555556555555885546645546666944575566646976666665788765666659352663543454448744646475586976A95665555565656558876777866776555555556566745656698B8659555787854673563343354424333345223614622515517325236252222322122221215-34324224583154443323442423243317132224311111111252213112221233211111111121111221111116453133329634536445547795555544496444522864476836644534543222322323232233743231624343544442222423344443553321121211312211111111211111443323423412234333232433433333222-2132211111122243222442332333-322335733243233233241233344322233223243332444421213512212222114221141111112222225112222323422333523111221111112443344422243423311121211112534433533425522345552226334112222232212272222233C6H23-314222222114221111134343342332514 BA5697H-XDH5DCLDBFDDCCAAFCDDCCECCGEDCGBDEDCCDCDCBCCBEFCDCCDEDG99CC9A87CC68ADDBCDA98AA8EBB8EFBJEGB9BDCFCGJGAGVI*yxs**tuo*mnsl**p*u***6****npkxdu*tqtooh*sv*gs***PRbFds*FYNuVGQiMEEEF*IIEJFZ**s8*kBCBICEF * b.40.4.3 Single strand DNA-binding domain, SSB
[  87] -----------------------------1--11---------------------------------- 33B-U314447212L7755-5I228K555556LHHJTVeP-74NAI783331IB9323--ED51P4LMRO262223323193211222ln*o-f544--B*9DJ*H*2p--------------1--11---118112131---C-N359113----14-41354-96MB-------------23---2213358898796B37AA798WNCB9CA99376K3469BAB97O*16665666666666545588A662--51334A91132126277334453654454444433344444354433543444474411-4442EGE6jKJKKONMAL7VNBB4899x78643DL--TI52113112412J-25G-HOEEB-1111JGgTW534LCAJ9DFFFDCEDFEM-GCIFFPBOIYB-qVVPbYeprgXcIE6AFCGSB69DFIP5555555587A3553F-----------------11-----------6DZ629FB9Py****wcYYYQnnyyhhiiGf*t*UbaR12NNOABC65TA9BhG6M9275AMA56555554335J82C23312437G449-6965348656659GY-2B-3211111-1---------3631433KIFBMXS6OC4BIFFFF5FKDDCFBFJBJT---2323------MHOMBNCJNNKKJLJOK-NKKNIJKJKLOKNMMIOMHckcPQEEFQSMPQOQONQPORNPQQFGDFDEH6-IGGFGGDCGEEE--27-2---55648GlKm33354A133223223PPQTQDP264HEknqkdzmwgdjkhOPLM1111111113GJKSDCCECJRSLRMUFGFGE7771111114-GH3587--------4-1------------------------------1-1112K1B -------------4-------------------1-1------------------------------------1-----------------------------1--------------1----------------------------------------4----52--2--1---1----------I--51---16--2- * a.24.16.4 Glutamine synthase adenylyltransferase GlnE, domain 2
[  88] 114735998888889917679798A56968AB58788CAAAAA6889989CAA637434-37551-77 77C8J978778877ACCAA-AD55CDAAAAA8DDCDACPJ6HBB98898886B8A99956GBC6HEKEFAC77779673477978787AAAA3E44122588BA9597611111111111111355768844497AAAED534E9AAAD99A66777766989978EEEA666766666776A68664669CE777778A88799779BDAAAC878CCDCGBC666666E777777777777777777888974899AB695DC9999889674777666545587767767666667555555565555566655566657C4575556765658A79956665454274477BA78954A555547135779EAAC75667ACFBC9A7CACAD9999999999B-BBDBBGB9BHB5GDDDCCFDDEDC9DB8A99A8888BBC7677777797867BBC5555655556--111111111111155555BBB94AGCCFBBBBBA99AAA777FBBBD898CFCKIH68888D9B7AGDABFG77B8AAC986665776A98D9A5DD868A768D77768887A6AC8FFDFDF9C854665555654644444446778788BA97CA9797CBDBBCDBABBDBBD98BA85239DCC2322227ABC88899A8989999-99999A99999899999988A9899G87777777777777777A998888977788887888888335966666BDBBAAFCA78796A644437778AAAAA8A878ADHFGGBFCCGBBB9AGFE779677767B998A88888998A988ABABA88856665684BBBBAA--------312-------------------1-----21311444545857 461177C-M971CBHACCBDGGBGBGDABBDDCEFBBCACDCCBABBA8DCEIECCB98999D8989989A9BA9BC3CB99BA99888BFBCABFBAAAB97HIE-BQF*FHEJGKBFCEGDGONBXA**Q3RIQBCCGHAEIBBDCBCLFEHEICBQGVWALF78NA9kLDS9BAE9*866CAI5FMDEEFLKJCFI * d.142.1.2 BC ATP-binding domain-like
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e*E2IBNA998F88DC9AB86C57E7C999JYPBSIL659CVBDLDAEDE*CADGDTNNeMWVFHRLJOL * c.67.1.3 Cystathionine synthase-like
[  90] -------------------------------------------------------------------- GC4BE---111---48411-1M33-211111-EAAA8I96EHDd*-------645-----EC3-J5P8963----1----K18BGRBC-------------------1----------------11111111181EHHCC111E4qQTKMM234FF---2--CMA1CBK4------------aDF849829C3888886784888888-44433887487H3KM4444449C11111111111111111111-225--8----3311-2-12111-----------------------------------------------5BD9M888A899D8F4WAB6566B6A--8GG8CJHHC56599922672--D5A8AA61111129YUUA7LaSLVY4799489789I-bWSUVASTBV72KTTVZcUccfJIXI8JC392GGDE8A5--------EHH5-mFa11222111111111111111111-11111-99HC3CDB72LHIIKKH8997GGXbBABB4ALVSISKU-3QPNgMdMQc16rA8YXbVKWadR-------56HOmt5QTKNNUVFwXRQS2NHOiJSHXVAAAAIB89OA99-111114-1-------cLVUH43ieLhmenVtVl*ustqnlhpomYnjhaY*y---EeKj------FKKD7N9JIIIJJJIKG-GJIKIEEIHIHIIHJJIIIILHIJ--1C6BDBCCCCCBCCCDBFDCB86BF3-F56666655666--1X11-1-GJJJGDyKq---------------9899958-2-MeVTVVadcckYXWWXYZc-----3---ZWcdTdccbaghezyRSTTSTQMMQ3333--h4DD86HG1111111191C------1---1-----1---1----G85HGABABB-1-- ----1--------------------------------------------------------------------------------------1---1------------4--11---------------------------------------------4----8---------A4----------1--B-----A---- * d.58.29.2 GGDEF domain
[  91] -----11-------------------------------------312---2----------------- A11-o-72222A75**qVV-VL88*pUVUUUVORRR****1YWS1----5---66--5--lU12*drah*A----1111-1-------------------Z---*-113-------------------2---------22---*-GNX-cdY--------------gU*7-------2-----------2--*44949I4L85C9JT4--MMVn34g1--C3--222223*--33333333333333-33-1--1--------2B--------11--------5--E8--------------------1----------------49----R-----u1HH----1-33---3--336--5----------12-4---------688-*---4R---2222222222--33-3413-4---3GEO22-2-2W-2H-----A--1-------------5---1-2------------------------------1---------9FGCEc*ISSJ889E***wNnCA9I-E-----O--E--J112E6--2----H----------C1---1-11--66----------------1--*d-----------------------------9F-145----------O-----------2--------------R2c6226222K2LL722-2242227277277222222227VC**5222222222222222272222222--599999455594----2524633212Fp-Z---------------889H8-7-1-fOcgVi*rzyHORVQ-wd*-------------F28888A--992292222----------1------111-1---1--------------------------------------M1- --11224-2---66egY*c********LLQYXX***paTYVWYIJFfV******dR**xMQL32212322--421321111111129BC521YFO1132146K432-469B1----1-----2-21---9C6152--11-2--11---1----1---14----63232---987--3-1831433Hxi**yl2589777 * c.43.1.2 NRPS condensation domain (amide synthase)
[  92] 11----11-11--1-2-------12225-3-2----1-24314-11-1--145-4223321------- --3151------------------1-------2---------11--------1-11-----1--1112252-------111-1--1--1111-1--2----1-11-413--------------1---------1-222111-12122241111112-1-1113115224811-1------1111-------1------------112-11111------1-1-----1-1---1--1----111111-----1---------1------------------1121--------------1-11111-11111---111-------------------21------2--------2--311-1-1-1----1-1151--------1-111---1111211111111111---1---------11---112-12111-----1-----1--------------1-211---------21--1--5------------31---1111112-11-------1-1-1-131-1-2------11-2----2----131--------------111--2132-22-221111-1--21--142448713-------------------------------11----12--1--1---------111---1212-------------------------------------------1------------------------1--------------------------1---2--11------------------11--1-----111-1-1--211---1-1---------------------1---1-2----231------3111111------------------1--1-----------------1-1------2-- CHACkif-*akKolyTVZfQRSRWWXYQYPRQRWTcXZWYVZaUQTYbeZVcWfXSURYYYbbVQXYR9NWQXQSSUAUQSQQQRQkcbblYVZXhZScUYYQkgkAski***y***ojvnn****U*h***X***yino*jz*zo*sbr*rf*v***za**fux*Tnmd*kt*qIcUg*gcXPU*iy*b**TXe*sxO * a.118.1.2 HEAT repeat
[  93] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------I--------------------------B-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-114552---------------------------------------------1-1---------------------------1-1--------------------------------------------------------------------- 1-22hhJ-948-LG*simUcYbbXdbbTSUUUVWZUUZSYRYYQTRTUWfdQ*SNWbWVVVWwFFAEB2CB7D8DAB6BB8FIHEMABB**si***HELISEJ**b1Y********qiYbch*l**V*****6***VdXY*Zp*rVtdkVvdO*c*pu*UaRYxw*EmUgnJ**g5fUWl9B5oB****f**GIGNKMC * a.158.1.1 F-box domain
[  94] ----------------------------2--------------------------------------- --------11--------------1-11111-1------------------------------------------------1--------1---------2---1---------------------8----1-----------------11---------------1----2-1----------------------------------1-------------------------------------------------------------------------------111-1111111-------------------------------------------111-----------------------------4--------------------1---------------1--1----1------------------------------------------------------1---------------------------------------------------------------------------------------------------------1------------------------------1---------------------------------------------1-------1---------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------11-----------------------------------------------1-- 1---23P-1-----1111--1211-12------11211-11-1----1--------------1----1-1--1-------------------1--1-----1-21---b3**********************B****************************e****PiZp9****-*E2------2121-22-1---1B * d.169.1.1 C-type lectin domain
[  95] 11----------------------11112221-------1----1--------1--1-----1----- -1---112111--1111----1--11-----111111111-1-1111-111-21211---121-1122111-----------3-----------------1-1----11------------------------------1-----G86955211445564453419A9F6453244444444-----------111---11------1------1----1-------1----------------------1------1---1-----------1----22221--1111111111111111221111122112221112221--------------1------------1--11------------------1--SKLL11111DBUXa88BGDEID7788778888C-HHHGFMKMBNR1IDDEIIKQQKKKFHFHCADIA5BADFJ545555556A9467A711-11111--11111111111111111111CJMG59BB8RIMOONKDDDEDFFRKFFFGAFQGPFKMF26EEGBEHBCJHPBQ94993333E422222224558944---------1---------1---4434BQ-1---1---------------------6697598AH7D88AAAAA8BA8997A79B6AG--24443------BAAB4A7ABB9AAAAAA-BAAAA99A8AB9AAAAAABCEDDD454B8ABABBBBBABBBBADAA999991-845455555555--1722222555546E7A433625222222114CCDCD7C899A1JKJJEIHKAECEEACBB2222222223699B7777798A78DDEDEDD8893222222-441244--------1----------------------------1-------1-1-- 4557QVJ-N793ABAQSRLOQTOWVTSFGAGDEMOMHHCGIFHA89NIPkTagWHGHEEECEDAA5674C697B9CD48B7DDCDAAEDQnNSRPMA8B9BEDIRP-D*V*kfYeofXTNTeeW**P*T**u1ve*PSQPtQSpZQTQMOgPIsVVSeWn*eNlhdP*nnYv*bwBKIK*CFDHMk***J**JKmcUjX * a.45.1.1 Glutathione S-transferase (GST), C-terminal domain
[  96] 332211BBDDDDCDB81194643EB555715B111111111111211211111112111115771-43 48H8V6-7334333PePFF-FU77NRHHHHHHaWbXNYbo6XRb65584534EFC56D22MVH3HORYUQE--------222D32222332B222222-BIEF8PHH9822222222222222222225222222788FF222A7728A5562222444222465B549422222222222297777--19596666666666676665B44576668868853333333B9255555555555555544455143333313122333332232344344354542232222222222255555555555552332223334246764444444141955553332341-74354A9673823A32232432B2BOFFF77788B8MHKCCFMJMJEABBBBBBBBAF-99F99L9CDHI4HGGDGGIJHKHGFKFB8CEFBCBBAFH333333337555686C222222222222333324322322322223DCQC29NHDOLFFJGLGEFFFDDILGFGGBHVNUJVWO46IJIGDAJHKGDTOO79C2446B65444442446KFI6PEBC24422944429E78LAGAACB8CLN8B242222222223244344443222255CB68ABE9AC9DBBBB8CJBAABCAGABCB2-47953222222C7A859A9HFC988999-F998888988F8A88988CDEDC79FB7877777777777777I778777842D8B8ABB9BAAA224968666BBBB6CCCI434272233234452BAHJB8E9A6GAKJGIHMIKGQEPFAJCF5333333334699E678879DAFECCBCBCCBBC45554446669A88111111112-3-------------------------33333232222B47 33--598-F773899BEMGHCCDJMIGBDCEEDCBFAEDFAFECFEDEBDCGEHBBEA9DCB88C6481A55A79644866AAAAA5467F6EA886767887JBE1GR7KHIA7DEDC99CCCPP9W6o*E-ODODDBBD9CDBCB5C7C89H9EIBJ8AA9GF9HD8AJAEK88GJD*97AFDMENQIGLCEJEF8v * c.95.1.1 Thiolase-related
[  97] ------2122122221-2-1---1-44--121------------31----2-------11--2---1- 66D6hA6AAAB413GEB66-6H--Bx66666BPJMJOW*s4O5ILLG3798BXQX95D--GCI8VGeltdD211143262C6O-----5563-211----7111F1B2D----------------11---1----23384---461111221112211111114112331111111111111E561124-D7HMLOKOKLPCMLMJJNRKMMFLMON9CDKJBBKKLLIKQW8BBA89AAABCCBA964549H7A4CI44969JJ66HFA4C776555666BAA947777777787777AAA9BABAA99AA5875548888AJ8DSKKKIJLJBIDDRCCBDDCKC5836BC42OP4955644A555A153214JAC9-----64WNO-2AD65C4JIGJIJJGGHb-8AX9DfAUVo4-*hhYgejzpsurWN673JMbPISaLJU44444444AAB3-62C------------------------------35J71UtlUdjjmhihULKKHjj**SPNOEHpZ*kswk35LLKFHEABjIfImeCG62445F61122222--28A8-CE454784297681838125433242347151-1------------------1--1119795CB95G6C7BA99687A8AB8787B6B---1212------HLUH7OCLIJLMKILLM-LLHMRHGMLKLLMHIKHHOTWTMN677OEPMOMPOOOLMONMMRDGFEFGD9-EBBACCBCBBCC---4111111----3FUP334322222211223LMJNJBG25298RQRRRXReKXYYY8QSQ---------1876G56556BEFDDAA77667545------1311------------4------2---1-111-----1111111256343D343123- -------------1--------1------111111--------222--------------------1---------------------1----1---------2--------1---------------------------------------------5----1--1---D-11---------1-1--9-----5---- * a.4.5.6 GntR-like transcriptional regulators
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oHG3DEE9BAABCBBBBBADDADCCBBABC9AAAACBB9AAAAAAAA8BAAAAADBCBBB4AC9CBBAD3BDBBBBCCCDDEFCBDDKAAA9ACADDJ5FTVLHLACHDBAB8BBBJF6K8Q*F2FGN99CAG8BF5ACA999CCRAG9BFEU*AFDCAGAGiRCEEDFIJ*KIIEIZMob9QPKJOLDGC * d.58.11.1 EF-G/eEF-2 domains III and V
[  99] 444823889999999A27778879BA99A99ABACCA9B9A99BA8AB899B795A488649893-8B 8A8AC9A9AAA7A6ABABC-BA99ADBBBBBACBAAABDC8D9CA67888A8E99A8977AC9ACABBCAC9888AAA5688B66678887B7B77-22467668687732222222222222499997998A9ACEEDC999B989AA88A89998989678B88CCA78897788A9897AA899A859A9AAAAA9898988988BB8888999ABCCA99AAAAAAA8799999999999999A998977597798766BBAA8857679798A8887777888999999999997777777777777B7777877779A4BB6668776869C9BB877685A46B97ACFFCD9686CCCABA37A98B8AA74444598E99899CA9A9887888888892BA9AA9987994BBBAAA9AAB8878686A7699BCAA9888888889886B99A4445444455--3222233334332555578897766667CCDBCBC9999AAAAAAAA8AB98879966668AEA7A9A88AA89878778666666666677786CC997BB79B8894898A98A888777997A86665889988484444444766676688989798877B9988A9A898AA9889A86156888342335AA879888887877788-8888877888878788887ADB77AA799A89999999A9A999777888874976777767777665855455989A76789777767578778468777778777786EDDC9ABB9ABBA99A98677777766778977777787AA89878776877766779777AA882222212141111112-111111-111122-1-11142655958886A87 851277B-A3338898BBA9AAADBCAA99BBB9B9BCBCABCBAB9A9B9BEA88A9BBCCA8AA9A59899A9DC9FB999B9CAA9BJ9BEAEBB99999BCD2BM8JDAA8BA9687787JG6D6HxB1CCC8677B58854777797477AA8A8HF6F7D6B68J77MAABA9*9999BMHMTARJ8EGDBBA * c.23.16.1 Class I glutamine amidotransferases (GAT)
[ 100] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----379---2------------------------------------1-------------------------1-----------------1-1-------------T33**********************P********************************pa*******a-3--1112--2-11-11--1-122 * g.3.11.2 Laminin-type module
[ 101] 331-1156AAAABBA73743432-B333957421-------1--311-1-342-111--113113-32 95E5W54BAAC233HLJEF-FP44TaCBDCBGKUTUISnh3MAXTBG85D94JGKA9C11EEC8U6dSWM921111312--4F-1-1---42-1------516-H2A52-------1------22123232212469987111858426223---1----1--12879E311---1------5553355-B1C668665681455545A4557845443236C54334433845654555566655668749213-58-8--4BC44373123383233221112323333323234341111111112111311232111224117332333433323111-1-1-21-311--112341341222331-362FE88811111E9GEI214EB7CA23343332338-FEDDFJCE9HH-GHHAGGHGJMJMBE4E789DABCB85B444444449AA43779112-----11---------------1---35GD731855APIJLJNJHGHFJJHNJIJI4ELHQ9JHF-156D29458D487A8478-312412332222314A6523911-21-4321--776122322CAHGJJ263----1111111112111111----1154188365D452644515344424345342--13433------7B5857BDDDFDGFFDE-CECCFEECDECFDDDCDD9CGA9C653A8C8AADCACB7A78BFC88BBBD2-777657766655---311-1-4333236HB---3-21111--2415577A46374G1GEHG9GGE9DDDDAFHE111111111-23364443436445AAD9F988C96333--146633451-----1----------21----------21-----1222-131434722 -111BGB-B65-24HbkmfkUlc**zkHJCBABCAGGHKKHIKEIEebawf***igZYOOKK8EL5B99C9AJ5GBDAEC9EDBCC836W*MkNYIQJJCM7JNGR-7TS*ABAEEDB89A9C6II7N7W*A1GGMEB99B98C7996868ABIBCBFHHJe7KDE7CAFC69AJ5DG9i436DIQWn*caT86rofdE * c.2.1.1 Alcohol dehydrogenase-like, C-terminal domain
[ 102] --1------------1--21111----23--1----1---1--21111-----1-11211--12---- GLb4*AADBBB7658AAAB-AH11CcAAAAA6dQSRUc*v8WTwViA77JJIHJH969--RLVA*Nyy*yJ8666I45-F*NF--1-1RSUM-L33B--4K4GBy7l5a--------------1441436684-6DHINJ87AX9OCHD77B87236647879A6NKON725322224223299644--3BCADDDDDBEE7DADEFGDADD9CCGF597FB22322233VM555646556555556466743-2-23-11-1121244132-1-2211225445343222222222222H22C2223326232322222331A8BE5554554154726421--94231J3452II75964548417211-E1IJ67F-1111DDiFT989HBHKH898A898777F-JJMLQVKPDbD2SPQMWRZYbXTT87884DCEHGGH9BI5555555555314CA7--------------11--------------9IbA-9DB8BRLOcWTRMMMEMMUYVSUTASbSUUbii24MPSPWEBAQKOObAALF9E7FD71111111528IFG8DD112A31763371345435C56EDEEJJB8311------------------1-1211DD5DB8F9C83CBBDD7CGCCA9DBBD9MG---6A35------OA789IKKLMKLIHJKL-LMLNKHIJKKMKMHIIHHDKNPCEWm7HGIIKHJIIIIIJIIHTGDAFEHFE-QDDDDCCCDDCD--M678657575439H9A22222311111122365655254127CYaWcOVNVNKMMICJEP---------269CACDDDDHJALMHGGEKED89B22221151BB7766--------4-1--11------1-1------1-----1-121111-14b1B -------------1--------1---1-----------------------1----------------1------1--------------------------1------3--------------1---22172-213-------1--------1-----2--------1-11--2-1-1----1-23--9-1-2151--- * a.4.6.2 GerE-like (LuxR/UhpA family of transcriptional regulators)
[ 103] 22-13-41-------11---1125311-42421-2---41443--5-2-453816766664-833--3 498262322221-2724----3--25-----334443643231-1114-2217542-2--1-61126875-131133354BA512---8887-8-24--37465667-21------1-111113212122112716873456366B77322311222333453613A8A8142122-42222-1244224689RRTRTSTVJSQUUVX58GG7JVQV669J565666665TF333222343333333632342552332321266445448411-3222221---11-33333333333--------------112231111-A775888748763443DD58785B21463464CC4C-2496534514B76-6444811-1232IFF42CCFED99ACB9AB9BAG-767569657P4-PNN9JNLTVSPM88463EFCFDHGKLP777777772-1628CD----------2211221111211112-3-C34945DHFAGFKKKNIAADDCPOHEEGEFAFWED8DCF14BDD88A99C8HGFA6B9273BFC355544311277A57J1CD8889JGGC1949569332655755274464222223113-----1-2341111HF49D38877B7CCBA4698874575748A---25121-----77B98C778887A8877-867986668887677777BDGGCDC9BA7AAAECBDACBABAID65787874-GBCBDBBBBDDD113B12122466633JBK64737A163523-15KHHENBB38625GHDE9KHLA7967A3B73322132235ADDE9CBBCSDHEGDDA86873331111--37553433--------51-----------1--------------6515223212-742 A2CDHBG-OB46FGLCCGCDB99EAFABAAEEDAE9GCBCCAB9AA7FDGGFLKCGGDBHHGA663753B437875728959875779AFLGCKIHG9GFFDHRON2F*H*PWLHUIGDGBHOGWUGVBp*R-SJa7BCAJEFNHDHDBAJ8AREOJIJSUECFHD2PBDBIQLRJJLC*BHGEIXmv*E*cQNccYYR * f.39.1.1 Multidrug resistance efflux transporter EmrE
[ 104] --------111--1-----------11-------1--------2---1--21-----31------1-- --B-1-------1-1--23-2---11222221-1-1-111---3232-121-1--------3-16-1-23-1---2221-2-2--1--22D3-5-----23-1361911-------------------1135---48879-1-51-423--22----------3---11-----------------121--1-----------1--11-1---------1-1--------26-------------------1-1-------------12-------------111211-----------11111111111112--------12----111-11----11---11-111-------111------1---1-----L111------1--22---32-11------------2121112-1-1-1111-------1-----2----2-2---------------B--1------------------------------13--1-----2222-1---------1----251-1--1111-1-2--1-1-12----11-1---------------8-------4-11--2--3--22---1-12------------------------111-------5--2---12226--2222--112----------------1--------1-1-2-------1---2--2-11----------1--1--------------------------------------------1------31---------------------------711112--1-1--11----1-1-1111-2----------2--211-2---------1-1-11------------2--------------------------------41--5-61- 221-14R-B7511112-2-1321323411-1--21-2111-111123-34214211222123-1-1-----1--1111--1-------111-----111--11122-GCE**********************a**************************e**w**tp**p*k**X--264322-1225225G217D64N * b.29.1.4 Laminin G-like module
[ 105] 21221372844555654859797696669BB96-1543445337A77I73UJB245254533252-64 4Fp4X556665323EDGBB-CA44XIDEDDEKJBEBHEKO1YMaE881374154C11611IGI3IGQNNR91------33248443342265-311--169477C79671111111-1-----174569A476A5FKKXT344M7bFLNGFFGEED555767A76EJKRN4833463A533464A67111525CCCBCDCF5EE9CAG774421BCB4216333133232GC125-2--111222--1-4-23-1-23-1---21--33---1-1232111--112-1----1---1---1-----11--11421---212--76586565436393338722319142273127ACC561-63212334438498DDF143228CLOJDAEEFCEH3555445555B-MILNHQKO8NH2K989MNEOJPEJJD6896BB977889799999999C998BGLA44322222221343454333233331212698K9436332BAA6B8A888877DDBCDB8BCBBB8C946AA95679A55CC8966F9346D834322236799C89CEG9BDC4NOB89BH98CHCHD9LFKIFT8K2458-44559416--11-1173358BB87555B3653658785C7C8A77C7667A92-2A95F12----66865755767676766-555755676768655555666977A86555676555556666577767578727666866666862135333339976C8D652111322----122244775453437BHHGIAAK88877C6876142222424396465555568755998797A687332321J7EE99C9--------311--------1-------------11-2322131332FJ22 5625JOC-K58375AGJLEGILDKKHIBA8A8BEJF9B7BAB9989EEBJLMPNBBLD9CDC8A95473A43CA9633534789B9846GLCJCEC854882A9FF27*L*HGGIFEB9B8CC8KK8B7W*C18BI8B67DABF8A759BE76EAFAEJjcFBZOM7C98G89KDCFIJ*FDIJHeQU*FoYKJELFGZ * c.66.1.41 UbiE/COQ5-like
[ 106] 33314423666656732A56526-E66G4IG455133-3-11335-1311855-11111126443-33 6DR4Z3267883613B933-34223F32232258785CBB8H9RNJG45IG3HKK54D1199B5O4QOSJ67577686-146621221A953-5-----17274N2836--------------1121111--12212285111D1978B5673533343433454AE8N83432345332249D421741A5899999A68568888875556886825647777888869O266666666666666744494BG37835545BB99AA3695CB566333211114422222222222111-11111111122211122253514944455352436211----A-32-3332233312134223315213446D665---1-C9BC91236744411111111119-78B7AF7BCM2-QKKCKKLVRKGKA85726684345854444444447A963435---------------------------1-14673638869EDECEFB5454BAHF555636GAM5867--5457352353689224213112--------1--1331241-2---35--1-5242326418CBABQ-31-3--------341-1--1132-22243394441-8242232424142232112223--21123------876A3B89BBC9CCCAA-A89ACB9AC9BCF98999AEFE871247598A89A9998889AA78987884-A87888778888--1--1-1-1232136961-18-6-------2-4434436132F3886859AA7988A7978211-12--1212242222222322659ABAB7794222--28332345111-1-----4----1-----11----1-5------22722656663B91 251298B-F66346DVNSRbTWPhdheGFIEEFIECHIGIIJKDCCdUToYfvhaXNMIHJHHAF5AICDCHL7IBGALGEHHGCCA9Dt*jNMzPKLOPGIGRNM18*Q*XXKPIUGDCJVIOkbDoG**P1cMcDGIFKBBcX9BCC8TDFTEJJDNFICBLOFRKHNcUNG84IKI*ABAJOWamlLSeKTlPVUw * c.1.7.1 Aldo-keto reductases (NADP)
[ 107] 65-1--AABBDBBCAA-253643H96661-7C--------1--------------------6771-11 4567e4-6442847p**aa-a*33**aaaaar****z***4wF*54552581AABB8B--RUh1QJaYNZJ--------384D-----11211133---1545774565--------------1-----1--1--787AB---DA53-3224--121---1-1-113461------------ABB8A--1G65777775967877877566666786AFDCC21------6413333332333333221113--1-1-1--1-22--------1-----------111------------------------1--111---211316444444444425332221-6-316-23-C915B9-1A---11-3171-VLLa-1---94kTc787XHXXLAA9A9AA797A-CCGCCKBKECf1QEEMBA9ECEACGO9WDADF9788D9J63666666C11129C611---------------------------1OWnQ19SJCWINQZdLKGLLFGGUJPPPPBNkJsf**o35JJEF8JGGYKMKWh25C-1-3662222222111I893sKO---1-1-----765-C-5--89A8FJ79---11-------1--------2-----33-BF796GD15555569G666696G7689--1221-------32842114334444334-344533342333444444535411682565345556454633522324223--122232212333---7222227777-ME44-1------1-12--2PQQOQGQ7A9L3ZYYbJVKQNPONJHGDF1111111112111311111351247787577555-------2DDBADD----------1-------------------------1--11-1----1-4 ----B99-E64-BBBFEFCFBBEEBDDED9CBB888ABBBBBACCCCD79ADGIAB8988A841111--1--1-1-1-11-11111--17H8EA9776679C9CEE-CH9MEVBBHNAAAAAE9KB9L9e*D-IDW8CB8L9AKE5BA8BD96IBDCBRBLM9PEED88EFFMGH3566m54465A9AIC6865HBA9D * e.6.1.1 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
[ 108] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------1-------------------------------------------------------------1------------------------11-------------------------------------------1-----------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-1--------------------------------------------------------------------------------------------------------------------------------------------------- GB89eZc-*fU-WZmaghabdddhgihYYYZZZbbYbaXYXYaXaZaabdggpiZcfaYcbacUbSUXPYVWXZaaZTZZYYWYXYQOOZ*agcbfYbabcadzry-f*r*******jbujipo**f*f***2*u*Yohf*hn*gYonidqXS*mqnopXlhWiaYZ*bi*chrXVidh*hecYf*x**e*z*vppmky * f.42.1.1 Mitochondrial carrier
[ 109] 44333163777777847654343596586885436675555665555685766334234554664-45 A7N4E56855735367755-5C445H455455DABB78IK65757H945653EDD4571145D9A5JFHG623445248545755556789A484421157385749AC455555554444446433454346545558855466C7768A444446556557746788875654655763585267542647777778987897889EECC7899859B5D448889885948888888888888886688B34-BD141269A22BE352223454889BA9C766888998A87999999999A99999A89432988D5558I77778779797D44788873562348435543434346774533754G45554444693MDG456796768879887767E-65966M4BCG52PKKDMOIUQOLMI86457CDB7AB89A4444444496754258333343333311111111111111143434467555A789EJJFJEE9899AAFF99A97DJAG79C833CB88295488FAHI552464494444444444332257466455676643452433225444546A5522233332242433333333223333486E7457278757676555556675777591234322222222EDD76B6IFFIIHIGGG-FHIHIHGGHGFJIFHHGGIFIGDBB8CGADFFDGFFDFDDEEFEDDBDCCD42BAAACAA9ABBD21215555556555289C5658674556358999979856453A67778768D67A855988423233232266A9676677868C567867868944441137444455--------722---12-11322211111221121213C444494648934 435454B-D454568EDMGPJHHTSMJBBCA78A99BBACBBC79ABIDKRPROIKIHECED65A35414559A866264533584546BLBDDFL9AB9698E8F26W7MDJFAAIG9IC9FAMKDPA**D-SDX8CA8LAAFABDB78C88PBE99FCL7DDCFKF69G67D96BE8*99ABFPJXXHQD9BDFA9E * c.1.10.1 Class I aldolase
[ 110] 6625335BBBDBCB993565573G63362348343333444433333333434333334435555-34 5774S3-5112353PhSII-IS33UQIHIIIJPTWTUhgf4TES65A86774DCD99C22JDJ2DCNYTO9--------222B32422954328224--5HDBAFAE6C22222222222222343225232423A9988---F372442223222332444222222E5242222242222B9C7522197GEEEEE9AGAEAG99A9D778BCEA8B98E63555555I7288877877877877787775355445535366555556676566555476564474444444444477777777777776554445556345979999A997B6C788944316711D3663BB584849942393356A27NIIH22222C8HFG667DGIDD78878888877-88A88D4B8DM69995A9888A876E8D969C97AA88822222222733236882222222222--333323324322322221BCWD27RL9KGBBOLICFEEDAAPCKKKKEEMGbAPNK44BCB77GDDFCCGOF43D2424C62222222442DA89dBL62323242222HAFB94A569989JQ762222244424632333333322223229925A6A77B9C9BBBFEDBBBBFBBBBBI2-45533------67E73567558766677-577668676656666766B9AA978D46555565665556556A55455565-4686888688882226686649ABB29C46232243233232232BBBAB8C886A1JKKMBMBICA89BAAGB3333333334444B78667B979777D9B99JNN44442248444588333333333-7-------------------------43311-5---3827 411-AC6-C4348B7CDDBCBCDLBLC87AA697B9DBAB6BBB77BABADCGE9AA99A9A633455145543474444444544533DC7DA8C7975A96A8937X9FBF959B9897AA7IF6I8M*C2GAJA766G79DB887BBD89E8FCBCABH8AB84HAAE45D95GH3d4349J****BlV799996O * c.95.1.2 Chalcone synthase-like
[ 111] --1-111---------1---12--111--2--11-1-----1-111-----------1-11---1--- --1---------------------11-------------1--1----------------------------1------------1-1------1------------2-1----------------11-1--1---11-11--11---11--1--11----------111--------------------1---111111---1-1----------1-33-------------------------------------------------------1---------------------------------------------------11111111---1---------1-------11----1--1-------1-----------1--11----1----------------------------11---1------1-1---11111----------------------------------------------------1---------------------111-1---1-----------------1----11------1------------1---1----------1-1111-112-1--1----------------------1--------1----------1---1--------------------------11---1111111111-11111-1111111111111--------1111111111111111-11-1111--1-----------------------------1111-1-----------------------------------------------1--------------------------------------------------------------------------1------------- 98BEHKP1J963GDUNKPPLLIKKMHKIJGHDHIGHJHDGCHJFIJKLIIIJIHEGKLKNOLJEGCFF6DCDEHDGIBFHDFFEFFLJMGLHKNMXKEMGAGKWZY3Yu9********w*wx****u*****M***v**v*s***r**ns*mr*x****i****msd*c**NXrXAkUS*IIENS*ro*M*rHNPvkmJ * g.50.1.2 PHD domain
[ 112] 44-2116998A99B871332432C85643359---23112111--11-1-211-11111114761-11 4889J638224766SueNN-Na99euPNPPPZjioiSe**3c9g3236333387887911EDR3GGQKBHC-111----151D311121131-1211--25445875451-1111--1-----31111121114188899---5A72162224411121111113144412111111112137656611-96988888669697A6675A88599A66EDB753111111B2122222222222222211132-1----1-----12---1-1112332112111111111111111111111111111111122111112211145111111121212221221-212-6-1227715372171--1-12-911KEEP-11-183cQU656VLWPM798A7786888-66B56N6DEHW-B77787CCADDDDHBKCBFH8CCCAEN11111111A33-1IE7------------1111-22112113----2HMgH-9tfPcILNMXJDEFFEIIOPLKLJBKSLwYrxe34JJEHEDFFNIRQXg64B21--98-------111PGF5dDH1----1-1--19A82G14-16766GH56------------1-------2-123--891AC3E5DB6ABBBB7BEBA99AADA9CC--133111--11145862648556865798-5988655768565668667555454546544455544454444845455561-555555555555---74534355551AE46322222111112342FGEDF7E9BAA2HHFGAGFEBCCDBA788111111111-343C444446A676889999999A1111--12887788--------2----------------------------1-111-1111115 3213HDB-SDC276CJID9JCGEJ9MHEDFFHGEBBCGDFHCFFFEDEEJIHPMFE9B98A8A46442232445433333655464111AK9ICBC76669DDIDG-DkHoQLHJJHEEEBFGEXIDQB**R-fJXEDEGKCHLEBDDD7FDCTCEHDRIQNEUIG9JBFQHHJJ6765y788ACKLOhBNGFHHCFAS * c.14.1.3 Crotonase-like
[ 113] 11211232443542372------1HDC855F84213223D69524114-5D32-11214213251-26 78V394866543559BA44-4E22C5656765a8HCFESX2EOS3323522EB2C27232CHP2E6GHGA63444FIE5468521321aPwZ2cB53--4L3E974CA452553322442222D232455442833334326AB5SGFH3611146G3I31456-3EEP12421231B3144BA533234653BFFFIFGG9EMH8CD4797367BEB7DP464B23366639CF7A55976BBC7659C75E7766A58657AB98775C55429BEB88746345674588E9798C579B97AA766565DC664A7967D67DB767A99BF8BFEC43437482427JC6F7OGIB2B54353933464JQ4574C42H68I9SMGC792898887888589M-QHJJGOGCHd94956O82TP57DF6N666N9FDFD98CCJJJJJJJJL7995S372222222222Hh223322232222222222DEAC36825PBCGFCBQ6666PNTdECBBCIEZN7Agc29OJJHFAM8IKRBD9B9BE4475C56234235CAf9G5CT9768BCkBAB56A2BH7667I7575697B5C525151162322321222A3446ED4FBEX5B7AAH5LOXOAFHOBGI7JAAI8B--59956------GBGC9IABVXMCLIQHB1VB9IHKPBJHWGGCB8CAAGRDRHRUBFF59AE6CFACHCE9GFEC6JLJ9E-GBA98DC9BF9G--5356646997C55848633482374556A86967BDD36BBC53CPA5C6F9KKDEKTPC322225222DD96HAC7MBID7CEC4PAOBG99ADBBA--435534442863--1-623-----121-13-------2-1-33221122121112L95 111-I11-J-111---1--11112-1111-----1-----------11--1-1--11-------12--------1-1------------6--121G---4-6112I--4C322--55----1122113-252-111-11-11-B2-121--1-112--611--2N4---21--C1-1K-C1221-211G1-2215Z154 * d.163.1.1 Lambda integrase-like, catalytic core
[ 114] ----1-----------------------1--------1------1--1--1---------------1- VU*-1--------1-------1----------------211--1--------1---1---1--------------1-------14634****-*FH3--a*VkY*I*a*-------1-------463755345SB----------C11322-33--------A4-cAS2----1-----1-1--------------------------------------------------2-----------------------1----------1----1--1-------------------------------------------------------------1-----------2---1---1---1--------51k2-****11111L8HAFEOCOB8IB44334344448-NI9IIENK319-78864354435AF4*oV41R558912-TPTTTTTT6SQb83dF---1------------------------1-b**jNAJEFCEKNMNFC8998EE84BBBA4ARAEECHH13A9F8IFBCd455J7AW78SCRE49FCADBCXC98MG4CC3221241323--31284368H6455KO33L4L6-5433616576774569B163EEAA4u6zpb*m1XbdhgUYNbfdWRSQmWPn--2A8B5------O8A85D7ADEJBIGF98-C9B8DCF8BCCGE98A987DDIKLBDF8866888888768668G89B557A2-CBCBCDBBBBCB111F---------8DE9JE7A4B435D54489FMKMRJ8T14CZyaeUbVmUeHUmUMDQNK---------5598A79989EBB99*******t*yCCCC-1429966DF----------------------------------------------Ks2W -111212-3-111-12----11-132------11------------12--1---11----1--1--2--1----2---1--1111-----11-2-2--1-1-2231-1-1912-4-4-----1-51121BR12413---11-1-3121-12-11--1-F21135-2--13--182211-3-----123N12-11y-1-- * f.4.3.3 Ligand-gated protein channel
[ 115] --------------------1--6W45K4EAC--4-------1DI1AE2DJC7--------111---1 DbR4L111-----14DB33-3O119F333332PJJJ6EMI8OGZu321434-F9G--1--68C-MBCniWE1------213-758434334212--3---8154H7GM9----------1111-43433156CF2*****433*E*dq*jjENIMN434214PYHI***S111111111221mG4738846544464668828898687722547874639285222222DC2444444444444445443221111112111111111111113222222111121122222222222111111111211122211122233B45A6666666464662231113391-7115DAADBA56445434414-H898556-----48LFH532IEEF912221222227-UTPTNGRM5A2-57788A49AB88A574513297783653333333348734MAB-----------------------------155A43333398445569122233DJ22222276F6856-26639CB56ABBA5-89A7587E52222222336EGF8eNH7CO78MREEC2cWcOXWbELMPVOi*BM2--------------1----12-2342HBCG87CBHC7FGHHHDE8MKJFEGAEFHE---7E9B------68ED4B48888887788-8888888888888888888AABA84365555555556555555775577562-644444443444---922121654686EB7--------------11111123-218BBA8BAABCAC9AHEFGF---------479A699998989BC76HIGIH9BA111111I4WWIKOO--------711---------------------1---976D84A4545H14 2422322-C36-A7C6AAA989A868622222222212221223229D56A67A37452556431111121132211111133333222385A3515666664446-658HFNJMQMGHFEGFGgYCKEt*O-PKYCDFDRCFWEBGCD9KCBYFHGEI88H4BG88767U34HB-8A39--279GAEN9N589r*tq8 * d.110.2.1 GAF domain
[ 116] -------------------1---16----313-1------1-175-3K-5K13--------------3 BJQ2452A4451-117733-35112353454273343A63123-2--23236557233--7-4-538765-511-7C2-495153458GIKM-D-----2J4C1KOL4F-------111----24328V727DF366588748B2U38I554131121-4116436GEO9111111121111544111126A8FFHFHKMKDJJILKN5EBB79IIL577C1E8645534KL321---------2--333216235345222211446511214242955453332245555556555522222233233223112211113ASIEaIHGJKGKCLA7EHH8898EDJ46DAF74MHBK8D1466656C1-3GL7G3394444255XDFG65BLCDE33332333327-GAG9B9KH1G81EBAEE7Q979IBAC3337778L786C377777777DFB14B6A3322111211-11222118311111111-214N5245559GHHIAHNB9A9YOONBCBB7AATTCHFO-3KHGDABH5LGEGI6DHV8686863443332234lAMA*kKBDND5NdHFM3kWtidTeCWFDCFOIDJT4876333325222222122HK9ADAE5J6DaBI6L99FqGHH7HBKEFGHJFEFNJ--23567-1----9559565ABCGAEJFHA-BAAAABC8B9BF999A99987976843CA9BBDACCACDDCBE79B8E99X5-5qggE*dtY8G8---622222585649N3F---221-111122346665644563C9CAADHHKL6GGKHJgSL11111121137A8GDDCDDLHCFFE888A8A8784434-1E5JJBBFD221222222-2-----------------16------3G845232224I12 -111331-111-21642428233344444-21211111-13--3223534342844134344-11223-2111-111-1111113--112722122-22113K457-63J8BA8FFDGHDFHGGaNDUDm*L2UKZFEIGMDIKFAHEBDJA9G5FC6c1-3443584436-384112---1--2I34F383--71--2 * a.26.1.2 Short-chain cytokines
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cBRJMIMHQGDE99HFHJERE**M5PKSEDDELBGMD7EC99F9CQFJCCIGRgCKGHBKCIVGIFCCADD*CFDCBFIMPAIIFDKDFHC * a.27.1.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
[ 118] 777385657777776669545565B78A7A985332223222476356556644795355C8567-57 A8D5C566665556B77AA-A955AAA9AAA8AAAADBCD6E977664556599996722DAC5G9JGEF744444442334955554555727--2334A58777778-12-111-32----15565565685688899444B8B6C866965575555576967BDF8555566566566A5444554477BBBBB99B7BAA9ABA67787AA9AAA7843444444C94779798888887875555744-3443533-443334142143545222222255544444444444111111111111153455533326D8577776877776679943337873548785996C6669766555374B678779-22-265F9D566AA99D46554554459176A66B8C8H61A7779DF9BBAF8B8889B66877B8E5555555595665769--------1-111122121111111----468A756CC78CCCCDD9BBBA999FDDDE8DCDB9EA84677979ECDBADACB4595755984444444456757499586567875641767776995AABB9F7776666555554353433433756574498588CA4A566977897D776676A86981115666321223B8C87B89A999A9999-99999899A999989A888BBBA9DB8A9AAAAAAAAA9A9AAE98899898-C99989999999442622212555566D89555544144436564B9BAA8767566DEDDDEGFACCEA9DCE64434554468AA7898899887777777779DE77773464887765--------3-1--------1--------1----11-35765646864856 -1219BB-B54388CBFEDJFJGPPMGGF9BBAGHEBEDDFEF9CEEFEHLJVNFGEDABBBADABA99A788AAA7899A99899658DKAF9DIBBB86CBBEI-CzClEIEGDD75498A8SG3I4X*A-CBG5B87E67E96A743B64J7FA9GJLI9VD8EA6E8CQQAADGD*CBDHEUPaiHYOEGNNLLJ * c.79.1.1 Tryptophan synthase beta subunit-like PLP-dependent enzymes
[ 119] -----------------------54-------------------------L----------------- F-WJ-QBN983a-K2NB34-4X--MDJ7KKH-PVNW55EG-24A3-3C--*4B1558*--7271--95B2-5---B5-1-47--1-D31-F---B-8---3-61EAD----------------1---754514-8-----1812-91----------------1G4----------------5-11----294----463978C796B-5992-8453A9714-2--2-2712221C----1212-2-3-23-65-ID-Q-6-116381852B65OkO561FAi9-951616665354332412434576252--BDB-----17-41121111-8-s-CC---O2BI-23-282B438E43-366A1--8-63CI88A-----12I5G4p26-2-32354334336B-IJB3-C2F541-37778-39535FBE151I421H7BD51igihhiih5lTe3J-1------------------23V----1-6--B-58---9*o567LI5S****LK757FD92A-HO-21Y-2BBQB7m6693I-3971B11115635-111-smLB-5-28144AE62138--9-39-BLF121-379-----------------------F-6-23-O39C-84--31oGOCCD-A8C81vLB846---1474------1155582DRTFI5FDBD-Q9E8R985*8T7GCBEDC3N592-8713C111D117AF25-2S8*******--IGCFCGBEE292--6--1-117-33531-FCBA-151121-1---3-813-5EBNGC47H44-46-342-7Y9E1--------4C-1E77757d2A9CK8YSrPWbeY1-----C-5211B5----------17991----223------C-------2B-Q-------7-- -2--F-1-----P-G---1C------2--2--1----------1--4J-----7---F----A56----L-1--37g-74-149-21--o19--82---6-CE-2*-----21576-1---------1-1711-11-----1-Z------11----B3317-1435u2--16141--2----11--cL4d4-q15***2 * c.55.3.2 Retroviral integrase, catalytic domain
[ 120] 22---2------1-2-111-1-12FCEC266D-1-3--466444A-3S-2213-4-5-54--1-1--1 1342231211312142322-242263333332544532225222C11-911-222232112252D2332221332222111-1-B85511------1-----1-1--8-----------------1-121--12-23346---1797A58832322------43213274--------------3-----3IAFFFFFEBLEFEFHHC7CCCHBEGG787fACG422232TH-112121-11221-11-11--1--12-11-3-2331--4111-1--1111-----------------1-11--1-111-1------1---ANKdxNNMNOQNMPaK2baI1--VJD1-8CDH7abFIC8LDB5237B3--AA-DFF61211341LTX318HQAES------------89I994FH21-1HLLeOPIPSOA8d-B-5-3-77646G---------A873-lMf-----------2---1-----1------1-1542498657JJKHJGiGDFFDDPSJJJJ9HGNTAKCG--GELLAVDBT-3N83DKG659CXQ11312113311DKJMCAL8GTKilMLT2XOWSGSPFK9868K551TC89-AA8A59484434444DOBA---bR1EKCMDAE2TZaZYGMIZRTXMQHOWXM--115C6------ERff9JC6664634376-6656644646646666664---ab329A896AAAAA997A66A635344451-D78887888887---111111211132UEl---------------111111-1-18EJLHHPXRgNLKNQReeg-----1---DFfbZcccdcORUilBBKKMKMACC2222--VmQQ88DC55455555J4--1------1-1--------------8-BBE67766-6-- 2122316-53231-423122224212-23-1---3-11-21--32312343131-112124421--13----1--231------2111221132241---141223-857WNOOOaHB978AN8aTAS8Z*O3OFa9G77K9EID8E996V55a9G9BKAB899EJ3B95P5295-23-91111--664244247555- * d.92.1.16 Caur0242-like
[ 121] --------------------1-------------------------------------1--------- XIg---------------------------------1---------21-3--233--4--11--2--213-------------686CCTVVP-W46---6TBFBiNVEJ-------1------76445774359B211233--1-CDC9B7C3333422B68593V8EI8-2-----2-----3111--22321111111-211--2112114211-3112222------D32112221-111111111112-----------------------------------------------------------------------921B-------3-2-3331--------2-17144733417-1-----31R6MXFFP12222NVnXriMfhZeWS8CBC8CC8B8F-hqZUoegh9KH-ZLLLKLUMNHHLPeCKIA6KADAB78BIIIIIIIIFTSG9BLB2221222211--2-552642223331-12178HH9BC8AIVZcZdRNFDDDPPbYMMMMGPRPjNYWk-9bdXGONJMoROFOJJUZKSIJFG2222222FAMCOVFBK379BB8EH8861CM7FFJJDFMOKLUK5IB4222333344666776666H739IFJHDAZPESOKHCMPPPOOUYhUSXPOZndZR--2NKAM------GEBEAMDFGIHFHHIEF-CHHEEGGECGEGDFFFFFFQUSEE79ADB9BDDDDDDB9D9BBKC8AB9DC2-KHHHIHHFDIII--2B68666BLJKXHHA9222225233333333EEEHEBG565KGSTUTQQTTLTYVNIIJL222222222OCONKBBBBBFMRLJbZUPVPPDIIB8B835FDLL8BHH122-2--------------------------------3---21222HMB3 -------------21---------------------111--11----------------------1-----------1---------1-----------1----1----1-21111--1-1-1111--12411---11--1111-111-1111-----8----A-3--111--3----1------1--C----1H1--1 * d.58.44.1 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
[ 122] -----------------------4CHHB-645---4-15765645-4M-2214---1-21------17 7HE2C33444444468B99-9922A8999987888858896979I533512214413111BA7-K2AFCD621121222-535216221121-3------31-1425C322222222222222-2122-113131BAAFF321H2ICDMED322441222413632EER8111111111111686332146CBMMNMNFGKFJGLHIHCKEEFEJHK69CVAKG566657Y*333333333333333444243222332231344333323222323233332222--2121222222233333233333331--------19KJJvDDDDCHDEBIM6JJ3775XDD--H6A75cbIHB8CC7443AH223AA5DFF92222367jkp876RXQRf55555554554-PLOJJBOf493-OJJfRNPUVWBCeA9456443A436G54444444479866*Qa11111111--111-1111-111111-----27913CC988GIIIIDSBABBAANKGGGG7EKGUBKAL11GNNMGQHDS8BRH5DPIGA7ALF3333333765DTU9aWAQBNMEngVUT3rgmZVmcMPOIHOPK8E332111111161411111111512233TQ5DJIK9G99HJNOLBNLLKLHDEJLHXO--23758------GNTOCKCCDDBCBBDCB-DDCCCBBCADDBCBCCCCBBAAPR437DBCBDDDDDCDCDCBCF979BAAB3-FBDBEFFBDEED---411111222266VCW222222111111123321232-112EBKKNLRVTeIPRRSOQRW---------DFQTUQRRTSLLSfdBDKKMKL9A91---11aMBB78BA--------921-------------------------31856553441B-1 -------------12-1--11111111111111111--------1-----------111111------------------------------1------1-3------19------------------------------------------------2----1---------52----------8--4-----7---- * a.274.1.1 HAMP domain
[ 123] 66A656777777777788777775A6679776546444666685456455A9A367566565444-34 7784A988AAA69687DAA-CA3389AAAAA7EBBB8A9B79AC978688A7778878448AA897DB89777779877779974766B8AD38861--88788768881------1111111156737545565999A98879BB998AAB79777769668788CACA666466665468A9AAA778899BBABCABCAEBBBBB9999AABAA889A9AA999999ACA9999999999999899999998988AAACABC9988889AA9AAA9999989B8899999999999899999999A999A999A888999AB9AEEEEEEE9FAAC999BBB8B87887866998A6587878889795957855723333769775655565467777676777-66977966AA63A888AA999999545476878A8887766666666777664A8433333333311--1--2-1-----22334495556555789999997889999C99998999ABCDA55CB9867878979755867666667778887667665A797B778688777478776776788A8AA865777566666546444444467668788777847587778B97778777777877772-6664722-3337B97A7789B8878979-98878887879777787787A9789CA787777777777777787777777627AAA9AAAABAA224644554767976A888888887AA9A87885556567776A5878797888A8A899AA65656756546998777777778776667666664444227955445533343434543----3-334233333344634333475577676667857 222289A-F5738888A99A79CDABC8888778769788766888E988CAGB79BA7AAA8966876789996997897567767987D8AA8A76877A7CBJ-9L6MIGLHO987776777B8F7Vv9-G6I5678848C757868754J7HD998EH7IAA8E5779DD66C96t66787EGSKANEB6MGEI7 * c.61.1.1 Phosphoribosyltransferases (PRTases)
[ 124] -------------------------------------------------------------------- ----------------------------------------------------1------------1-----------------------------------1--------------------------------------------1---------------------1---------------------11-11111321-12112221--1-1113111----------1-----------------1------------------------------------------------------------------------------------------------------------------------1-----------------------------11--1----------1-------------------------1111-------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- A9GJipO-H57HURRKJIJLHHEKDKKJHZKKOMKMCGDJCEKFFEGKCFFHHJ9HEHCKJHGDGCDF5FHBGGCCD8DDCBCGFBCC8JRBJFFQ98AA69Iaiv8V*qv**v***kmpmo*m**h*l***J***jnoa*nu*sZyqek*aa*t*xpvIaeSYZbJ*QVcNcbSdniK*WRXPZ****M**fhs*r** * a.4.1.3 Myb/SANT domain
[ 125] -----------------------------1--1-----------1-11------1------------- GQw7*997776876FIHBD-BE33IOBABBBDLGFGLFPNDLDROQ445666F9A23811KIO3dDXemdD211121111C8B42444ceib1V761114N8GH*E*9s11111111112222132334433555HCCIE224TCV8A87777877776B89656I997957455659454595222442C9DPPPPPHLOBNMPMNODIFFFDOLQBABJH86433444kR444444434444444344235223333122133222231232222122223331111111121111111111111211111221112222COICPDDCIHJDHGDDAIG9887KJL32NACDAUSMCFDACA9A8D8733N1dPEEI4655579KGI7HAEDBNG6666666666C1GGMEHMFK8K73GFFDIHDHKJCFCGCA989AB9DDAA866666666466658IB2232222222334323343343443423538AFH49EDB9GIIKJGHDEECFFKIGGGF9DNFMCGCE44BBD8A6A9K8BBE59RA776EB44444445N579DD485234453864343675554746QLONh*39811111111131122111111312176576DBGHADA79AAAAABB7779879B89E2-3866923233364765776556655565-5665546466566666665666DC78655555555555555556546545633855555555555335C444446656359775555545555555555454457333KENOLNOUQRCKYJI9BCD2223222225688877777B9998IIC9D9A99A4444335589ABCD2232322254272G21-211112-11111--2111152555545446d46 11--12117-411412-2-123-12-2522-4422113244-1-1-34143-5--12-1244---111-1-2--211-111---211-2222-3251121221-23-133D38487443556A5CF374Up95D3I8455A457225711632769A793222484-323313342243B23134I8AI2A78865624 * a.177.1.1 Sigma2 domain of RNA polymerase sigma factors
[ 126] ---------------1---------------------------------------------1------ -----------------------------------------------------------------------------------1-----1-2-----------1------------------------------------------1--11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------1------------------------------------------------------------------------------------3-- ----1---1-------------------1----1111----1----11111111--1111111-1111--1----11-11----1-----2----11111--1111-1--**********x***********G********v***k***e**h******U*t****u*******R--------221-12-3---1---- * d.58.4.17 SOR-like
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rXXcaKJLHMTMoXIgO**V2cUmAMJKdLOOOGQLIFPHFSOTSORIMTFJHFAFBIIBDHFKTQZ*YXPMJXepy7aYWZNMIJz * d.26.1.1 FKBP immunophilin/proline isomerase
[ 128] --------------------------------------------------1----------------- --1-2----------------------------------------------------------------11---------1-------11------N-------------------1------B-------------------3--------------------------------------------------------------------------------15711-------------------------------1--11-------------------------------------------------------------------1-------------1---------------------------3-----------------------------------------------------------------------------------------------------11CC-2413-------2-1-----------------------------------------9-------------------------------------------------------------32------------------------------------------------------1--1-------------------------------------------------------------111-1--11-1-11--------------------------11-116684-----------------------------------------1-11-------------------------------------------1------11-------------------------------------------------- 2234**a-*xxHPPfCBBCDDEBA7AFEEED7BBCAC989ACBABDF9DDCDCBBB8G89A8595566-87897887398587989123EqEBUYR96AAEB4ZjM1**********sgdhr****i*t***5***Ywsk*w***a*xmi*cU*sznxvYbHW*reOhRYKBM*P8ogM*DFDEEu*u*C*zXqf*n*w * c.10.1.1 28-residue LRR
[ 129] -------------------------------------------------------------------- ----21----1-------------------------------------------1--2--1---61B425------------1----------------------------------------------------1---1---1--------11----------------------------1------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1--11---------------------1------1--121--1--1---------------------------------------------------------1---------------------------------------------------------------------------8---------------------------42-----------------------------1-12--2---1--11----11--------1------------------1--------------------------------------------------------------------------------1----------13--------------------------------------------------------1113222222315511------------------------------------------------------------------------ --------------2--131--13--2-------------------1-11111121-----------------------------1-----------1---1------U9**********************-************j******n*********rhp******59*K-11261--J---2-11-6OFFTR1 * b.47.1.2 Eukaryotic proteases
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b*D1IDH5868D89C99A875C94E7B78CFPU7FA98D9FRCHDBA9AB*9998BJA8HAFBDCKCFB8 * c.26.2.1 N-type ATP pyrophosphatases
[ 131] -------------------------------------------------------------------- --------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------ IFGGvtZ-*QK5YbXMNLMNNNMLMLKLLKNLLMNNNOMMHNONMLHLOOMMNMIMNNOPOQKLJDFE6FEHKHJHIAIIFFGGGHPMPITHNMJNPNONHIPvxv6aRP********u*z**z**s*z***N***puvu*q***i**sg*xZ******m**sxodb*hjmasvlDLPDuEHAHJXYfuMrNGFWjZeB * a.69.2.1 Ypt/Rab-GAP domain of gyp1p
[ 132] 1-----1--------1----1--11------1-------------------11----1-1---1---- 153----111-----------1--1------11-------1-----------1------------1---------------------1--1--1--------121-11----------------------------------1------22--------------111------------1-----------1111111121111111-111-111-2-----1-111-------------------1--------11-1--2-----1--------------------11-1----------------------------11-------11---2------11-1-2---------1-1-1-1---1--1---1--------------------------------------------------1---------1-------------------------------------------------------------------------------------------1-----------------------------11---1-------------11--------------------11-----------------------1-2-------11-----1-111------1----111----------------------------------------------------------------------------------1-----------------------1-----1-11----------------------------2----1------------------111-------------1---1-----------------------------------------------------1-1--1--2----- 1-11-1A-6355654248563486457876646456886868779875536754345I4334344355222-3332412343233311433242145134161A26-313**********y*****u*o***l********o*********z*******JPqF***b*pl*Lmob-341-211--674564F1366GA- * a.48.2.1 Transferrin receptor-like dimerisation domain
[ 133] -------------------------------------------------------------------- --------------------------------------11------------1----------------1-----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-----------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- 3632FDD-I87-ECC976956655264688A69876496878856676696978668766555867851878669773566456877B54A476636455469KJL-JNY**********x*****o*****R************x***x**m******o**ysyWN*TX*Om*m1879Z9AB37RQNgASI94ETWQ9 * b.7.1.2 Synaptotagmin-like (S variant)
[ 134] 5524213C86878B9A27647334E89E7FG964433335443DD58939J8I56443353B852-67 26B4*B5BBBF554MDCAA-AI33FTA9AAACIWVZPZciBUESRK88BPL7OHHE7D--CDJ8bDYjmZA355514545AF7---115634-322---1B343M6823--------------132212421254BAA45H59C55-133392211--1---11-836481---1---1---B752131266MKKLJLKORDLNNOMM9AMMKPKKM6A9J7GFEDDEDGTV9JKJHJJGKJKKJJJIEFGL77M18834736LL6699E878ABC9C66654549GB785687877665444446544444A6644466664A8ITEEEFGGHCBF6HON46A7B6L8568652LIBA6423457C66335A-9HCB7-----B8fQX75AKDGGCBEBEEEDCBCJ-99I99MACJWI1eOONOLQTWSONJLADBALL77998DP77777777A6877ADD---------1-3------1---------114DUC3DEBAONRSRSQMGGGDQQSUHJHGAFWOYMQRH13MGJ43875Q9IGP95B22224F42222333---8625H986327298667-5773447569937BE3631311-------2----1-11111-43966563839766AAAA696AAA9C6789BC2-223-4------79892A44768488655-5537564665657554558CCB766567776788677666666B554555582444434444434222312122333323B3C-112-2-----11117676527---81ECED8AAG98C8A49882----1---1186B66656A9B5648ABBCB8883333--35884555-31-----3-511-----------1----1-1----5287333234-484 -----32-1-31423223122111212223234335222223323324421323-2513142--2-12-11111-----31211221223--2-14-2-116112D-2-373C2226221122333172BP5-437533152132-212151251321622-2233-423-1221-12-51-121512A43-1175-11 * a.4.5.28 MarR-like transcriptional regulators
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cNaMMLOROIFHEFNHiRESLu*W1OLWCJHEPHLMNCHFBANACMJKHGJ88CHKHFCI9ACEELC5E98tAB7EDCEGcCQC8FHD97B * d.113.1.1 MutT-like
[ 136] 75-1--ADCDGCCDBB-253643HB6661-7C-----------------------------6771-11 4557g3-5112846j**aa-a*33**abaaap****r***4zD*1333121199A769--RRe1IKWWNZH--------384D-----11111133---1545664564--------------------------787BA--1D832-2221----------1--11231------------98979--1H545555547556556553455555546CCAB11------6312222221222222221112--1--------11--------------------------------------------------------111316444444444424332221-6-316-12-BA15B7-19---11-3161-RJJY-----42fOU765TGTRK88787885759-56C66I4GC8c1B77B67797A78BK7UA8BD7667C7G42444444A11--895------------------------------PTgS16YMEUFGJOWIDDIIEEEQELLLLALXDff**p25GGBA5HFFRDJJRf-19-1-1641111111212H764fCL--1--1-----765-A-5--8888BE77----1-------2--------1--1--54-7B477DD15655556D555485D6478---221-------42851214334444334-344533342333444444543311562665356655464644632323223--233343323343---5223227777-IC21--------------1GGHEGAF47581NNNOCKCGDEEBCE758111111111111142222246244665556E455------12BBA9BB----------1-------------------1-----1--11-1----1-3 1---8A9-732-AABEDFCGCDCC9BGBB9A9A999BBAB9BBBCCA88BBBDJ9B9868885-111--1--1-2------222111--AK9D88866668C8DCC-E77KGWFEEHAAABCF9JD9ICZ*E-HCV7B9AC8DIB7CBA9F96JAEDCPDHI9KCF798CDFMJJ3475k43355699EB4765FADB9 * a.29.3.1 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
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b8H9A9E78PCBE8EBB8*988BFJENQ8I9FC87546 * c.84.1.1 Phosphoglucomutase, first 3 domains
[ 138] ------------------------------------------------1------------------- -----1------------------11-----1------------------------------------------------------------------------1--------------------------------------1-----------------------------------------------------------------------1----1------------11111111111111-------------1-------------------------------------------------------------1--------------------------------1----------------------------------1-----------------------1-----------1-111-----------------------------------------------11-----------------------------------------------------------------1------------------------------1----------------------1---------------------------------------------------------------11-----------------------------------------------------------------------------------------------1-11--------------------------------------1---------------------------------------------------------------------------------------------------------------- ----1-H--1-1ABDACCAE9A8E8BA9846577866A88688867A9BAFFB*6BBCBGGGAA989A5A889B867477689988434HI9CEES989A49Dhit-Y21*********wq*****j*****6***h*un*q***g*wvh*ua******epl***mf*hv*Tu*S1A42312-26****A*w366766- * a.38.1.1 HLH, helix-loop-helix DNA-binding domain
[ 139] 112---21222221--111111--7331-1443151-23221-4734855548-1----21131---- 31143337557433522AA-AE22D2AAAAA7G7A96735-1432625633222B-22--426261734623233344216-313-233442-411---23233242431111111--------342334132-323365--1342C856872222-1----7924A943----111-1---253441234144434348433455743111344362113212655556321111211111111112211-974478438586622986145446553221111244212221111122211222112222221443222132344899787858538874463735213-13544736533-276732211316335-1--1564385165543233333332334-48426869437-3333323733365B1429-5665611422222222442-2444----------11------------------2523121---355444265665544677735678464922BC53438764264-637433253222221211555511422134351664-223334234577437631-22-2222231121-112111-223434522211222111111213222311-231---3428------23222421221112111-211111111121111111158521-2-3332333333233323411----1--433333333333--12-----12348-411----11-1111--11111111222254666836452333233231111-11-13---------1----3211211111------2444--12--------1-217223-112-11-1---11-1---111311132112453 C878LNL-fBA9HEKHGIKIJJFGKLLGGGGDJMHKIIFHFFGEEFJGJMPQYaJMMJJLJKD7B8BA1AE89AEBH3BF9CEDABDDCDQCGLDJDCCACDFSNS1IMZOn*o*twVSRUeeX**Q*X***D*o*LWTRqRaxcKbTOMqOK*XzahoMf*cKGRG*MMxPeJC9HHB*789DCZZe*JkRAAYeSWG * f.33.1.1 Calcium ATPase, transmembrane domain M
[ 140] ---------111---1-1---------------------------------1----1----------- --1-1---------------------------------------------------------------------------------------------------------------1-------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------1-1----------11---------------------------1---1---222-2-2----2-----211-11-----------2------------------------------------------111-25111135444433226666153412222--1-11-1--1---2--------1------------21----------1----1-1-11-1-----13---1----------1--------------1-1-12----2------2-----------1--1-11--------2-1111-111-22221----1--11-3121-----111111541-21121-1111-1-112------1--155555545654---1-----------212----1----------2212221---2-3333112222222-211122222222-31221111114322--1-2--222------------------------------------------------------1--------- ----FF*--1-133312321111122333121321223223111121211132623121121211211-21112111-33122122111321231122212-13142W-4y*********************6************z******v******u***mSRY*ce*m*VR-131J-11-262582623335341 * d.93.1.1 SH2 domain
[ 141] 3312333311111112121-11-489833362112123-1-1-4626A55476--1----211-21-2 5422554657624376555-552286555557746577783333662275435A8464225565454566322224431--2623222114312111--2445453222232222333233332532433545444563722134D77777955445767877577978A445666855856345442214525656656777764577633458764548644333332A24555555655555456334392324523111343346252345333447464444444444444444333333334333344434444432772833333235344133355332254823333345614343654233334433354444444477345556754444444444A-5565648733736334444454445675594564445553233333344344544445543334333233252232322222224558849887887797977787886887886777788B545774A85865BB768A8C9457676766666768A694444535417522422644786288568AC36311-222223121111-1-12424566676785D789B5778966598785657A98214578C22122265466776666666456-6667666666666666665666555746666666666686766A6666666637777777767773325434335767B6C6666674446655567733443346789698AB568958678C7575454544548988788888BBC9975788887775666426433332311111211223----2-11-21-1111---11111-33344333333533 AA44HGI-R9E28CHAAEC6EBAGBHB8787A8889BB9B9887BA9A7A9AAB88AB7698K9F8B95BBBBA9CAA8E8ACFCABAAAGAABGBB778679HAE4BzHjFNMNEEKHILMPGNVMhOq*T1cSpIGLOXIKXKIKMGHQFISLNRHPReVGOJL8RFFYFPRG7MHK*JINOIfox*E*aIPUXTVQ * c.47.1.1 Thioltransferase
[ 142] -----------------------1-------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------- 1222HC7-9471896FHLA37577747557A98666A877977687EA8AAFCH66A9E859F232331322423222223333424556G8H9A934455368FC-F*Z****************w*****R***z*w**v***n***u*sn********wU*s*c****c**D3OE5N3356EU*qfHpI88AB8A7 * d.42.1.1 BTB/POZ domain
[ 143] 11----1-11112211--41---27224-2D3------------5---1-11----1----1----4F 7D6-565766635363633-35--6133333351A48LHJ2525-3332---D3C-3---89822447582-----------53-3-3------------9-F33-5-2--------------------------377-2---573593BB--12213-4535--35318----1--3----2313----D-33333333--4-633-33333333436A83-3---1--741---3-----------3-3---4-33-3---33--33--3333-3---------------------1--------------------------123332---1---------------4--------2------------5-2833E-----5B99JD8J645365555555555A-6974EB74E67-544AB9M936CC9Y365G--121333F3333333333333-----------------11-----1--1-----9679--3336555555377779922ABAA4A588444C--AGCL52B58C6121D7-64225622222-2INC3212--3-32--2-447-BA86E8411A7H7BT-3-113-333323------------49113-4557-5-5-2-1--54-4---7---3-4---93-6------69693667776766966-7976666669767667666969336676666666666676666666666663-666666666666---9-3---4777974-355553533333339663366-3333658888C9B4CEEEEA6493--------C---511111414446333333444555533--442222--------1------1------------------------------76-2 2---33C-64419CAjOaOOIOFYkRVCC8FEELKN5989969CBBbOOUhehvJIrRJYXX9A999969A-967993A9CDGFAA343GMrOpIcFGGD3XIJII--m6*ZYT*ezMNQKGXQ*ySLM**Z7WS*TQYRbTUchTURNTaRIuXuabLZfy-LcBEOKM*5982-RE351-2J9h***Z*y28MObj9 * b.6.1.3 Multidomain cupredoxins
[ 144] ----------------------------111-1----------11114-1111--------1----12 342-21--2211-1-2111-1---2211111111111-22-132--1--1--221-12-----112212-1122221212321-113211131411-11233724322311111111111111-1211--1-16125534---329AB8BBD79AB5656849594FFF7566787787756---11111-11------1-1------1-11-1--111-1121------221111111111111111111121-111111-1--22111-1---112111111111111111111111111111111111111111111112312411111214244143321231133-32--42322121-21112123-21122223222546753324232254445444445-34534434455156665644755543322312212241233333333322335433333344423222122221222222437631221311112333333322223324222222333222232121421111412312342122211222222221623356222411422212435-244317768G7343223222222311121111143312225523634365534444454444434334341-3412122122243333334444444444-4444444444444444444444333444444444444444444444444442133333333333311224543332234141333334344423233322342343334344444453433333566211111111365544444444544221212211111112142434443333333333-1-1--3-112-162-11111121--11-111111211112 eOJLPLK-*Zd5RWLKIQRKPLHLLIGNJKJINJLLJMKMHKINNMNJIHHHKJCIGHKKMMQHJDIJCIGFKIJFGAIIFKKLIJHLLHXOINMQHHHHFRGPMT8Q*NlkhfcgUUILNMaP**N*Q**k3pctMUQPdLRjVPVSONaRNpKZVVUYeZTSVSEfOWzKTTRGRSe*dcRQPyx**I*jVkPTRWl * a.2.3.1 Chaperone J-domain
[ 145] ------------------------1----1-------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------11----------------------------------------------------------1-1------------------------------------------------------------2----------------------------------1-------1122--------------1--------------------------------------------------------1-------------2---------------------------------------------11--------1----1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------ 5421KQu-D34373C77979778786777988999678787888786B6788A876978787466756257654557677655555544671766B42443D4GDF1XnN**********************X************q***y*zo******Xs*irwhS*kptOeuS3DDCH55474HC9HBEF17CIGHI * a.60.1.2 SAM (sterile alpha motif) domain
[ 146] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------1------1------------1111----------------------------------1-------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------Q-----33--------------------------------------1------------------------------------------1-----------44-**********************S**************************Qc**qnva*cY*d*od----11--1--------616GCB4 * b.36.1.2 Interleukin 16
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c*H2JDIB988H8CGE78995C5AJ8A9CD6998C78BQ8DJ86877EBA*8AABFLJXdCPMACCQJGA * c.2.1.7 Aminoacid dehydrogenase-like, C-terminal domain
[ 148] ----------------------------------------------11-------------------- --------------1------------------------2------------------------------------------------------------------------------------------------------------------------------1-------------------------------------11---------1---1---------------------------------------------------------1------------------------------------------------------------------------1-----------------------------------------------------------------------11--1-1----1---------------------------------------------------------------------------1-----------------1---------------------------------------1-2------------------------------11---1--------------------1----1------------------------------------------------------------------------------------------------------------------------------------1---1-1------------------------------------------------------------1-11-------------------------------1---1---------------------------------1---------- 4311eeP-QBA49CH7776576668776666666668887679777786688769555756665545414534564433446554556659478474446556IFG4OfR**********************H***r********l***y**i******Xo**imXW*Zd*Zs*X2879e44446DAAK6HM32CFGIF * a.40.1.1 Calponin-homology domain, CH-domain
[ 149] --1--------------------Hf87G6IHW--C-------1**2h*5MrPV------2----1-1- BPd-53--112----21----211-1------221233631-38A11--11--13-----118-82BHA56---------829136128775-711---2E193KMPUB1-1-11---------7457A12DQZ2PKJMIKACL6rPh*KK4CFEE233422COFAow*D34A944444994N241-2124353332323344343441266644546466155-111-1HA-11111-1--111-------1--1--1-----1-------------111----1-----1---1----------------11111-11112E24H1112122426-743111-2-3--65183BCHC7Q3A4332621--H4LCBBB23342B6POTC63PMHFN33333333335-nhgnbPtxAGF3EEELMHMGSLGIE575D362D9CF8522222222251153dKN111------------------1---2-21-5583133314E8AC9975445CBJN566513ACHBGE412CCCSFM9AJHHQ95ABP96FFOB111111123DKRh8*YPHMsb8*niey1ud*bNcZNi78E8QpUp4-11-1-1111---------67-3A11E93A7AA8A7DDAB9ACB9BCB8C9BA8BE--17CFD------55562635556566664-46557355844555554543332212-3333233333333333635222361-C23565444566---611111465565I4A111----111-1---333331--1-5DJKKJGLOLCGGJGMLHH-----1---D223189889887BCABJKKLIAAB2323-1Y-NNBCJJ1---11------------------------------22--211112-P14 ----52--2111--G47B81343-3-111--1212---------1-4834765A4673243421-11112-1-2-11-112-----2121127-32---2423333-171224457311-11224411-5H41416412122121-21211223121172--1323-312831722131-1-2-6D94Q87431HGRK3 * f.55.1.1 Photosystem II antenna protein-like
[ 150] ----1------------------------------------------------1-------------- ------------------------------------------------------------------------------------------------2-------1------------------1-------------------------------------------------------------------------------------------------1--1----------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------11-------------------1-------------------------------------------------------------------1111----1111-1---------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1-------------------------------------------------------------------------------------1----------------------- AA99QVV-nMI7NMLKHOLGJLJGMGJJJHJJJKJLKKKJJHIKJMJEGGIFFFGHHGHGHIKIJIFG7GMHLGHLKBKJJHKHHIIHHJSEHIIJJHJhEIIPLf5UgN*******msryp*n**b*z***L***nrom*ly*vjxjih*mi*f**yxf**ihdnTwRU*TgoWDIIC*CFDJNRfbpJeTKIRXTXP * d.3.1.9 Ubiquitin carboxyl-terminal hydrolase, UCH
[ 151] 554-3--63333314-A51---174222262-11------11-1----21423122-43222222--- 8784E24466622224434-46227J4444448EEE4786622ACAE56644A8A422--8AC6ACEEDC64444366-2-3D21---44A826------7128C1H4F--------------122-222-2212677AC11265554355323335545744536554523332223-332AA2-2CD2C4A55C5C9B94AAA98ACACC7C9A848869646888666K4666666666666668888C86C-6C28224AA98GE64855464445422222--444444444442222222223222422---2224A72672222222924B6--4442G42414652122121-822586683224-82223-----918DD533325237979779799H-443443437E3-MFFDJEIKJDRP32533BCBA6AEG7533333333ECC7--3B---1----1--------------------12732133335BDDDDB79AAADD9DBDDD9DD9B54551-546A34545466BI322311252111111124122228A8-223222332-2-2324-1-22325912-------------1------3---31155D357-15555333533955555353557--27253------JADB4B7HHHFHHFHHH-HHFJJHFHHHHHJHHHHHNNNPCD997HBDHFFFHHHHHHHHEH96B99BB7-DHJJJJJJJJIJ---355335453315A5A988F3F-69867AA8333333345358BB9B595B73335577522232332233337444444553533747442223333--2644444444444424721------2-22-2222222222----44D44ALCGC2A22 22--568-B6A23866976C9C9D8B9999989998989978989898888899798768777796882678A69884A79889782327B79A898664686CDE-9B7JMODD9I8AB79F8cQ8H9q*I-PLOABAAICBKCA96E8C89V6BEAG9NE6DABFaEIE8BG76989q66685D7DE6ECBAC6879 * c.55.1.4 Glycerol kinase
[ 152] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----32------EFH**************szu****q*p*n**nol****************eqxPfcEdQNvVrWWIXZWfnmltGBIZng*d*uyw*jKO*VjQ-AM*----------1-11----113--2--111----------121----------------------------------1J-*--13----- * g.38.1.1 Zn2/Cys6 DNA-binding domain
[ 153] 22111-12222222143--11-1-51162141-1-----------1--11532--2-453-4111-11 BEF2R55565624157988-8811998888795AAA88FE78688CB57BD4ADA423--9886G59TOH686664442-1-542433HHKE3D443--7F58CG8GF9222222221111114676979888B9HIHCB222I4MGG8CC454333466635527A8C8243311242331GCB455433B5EEDDECDB9FEDCED8A884ACEC99766LH7887868K73334332443334421153572157-2436881146232452664444654533333333333333322223334222244422144438545A4444444A4896332ABB9298266A64A95553A8669B8B415545A66622222279985559A78922222222224-88D779898782966ABB8BAA9A44A76753BBBB552222222225331559B2221212111112222211323113313335333235345666456856665569656644464774222445615111416A333736386223222221497645545265559455755B646753D9989DB46342555555444575554465524222DCAA4A63D6A38657692766376374382-173152211119D55697899A9A9A99-79899999AA798688777ADB9855478476777775777779786788831799999997A98223311111455431C4A23257512213333344464532229F55654678A8887B676111111111569AD676769BCC977FDDDEBBC44443255BB88AA33323223735----1--11-1--11131--2----38964728884D6B --2499C----2116CB98DHIJEGEG7666572343655443655DDCE9CACDFBB86773272563321717893E82554476989EAB6C697983F5445-8D3NAI9EG986688BAMH7D5W*H-IGE6796A68H988965B47D788879HZ5HBE7HHOE49934BBC*797FCEMUNBEQ1-2---6 * b.71.1.1 alpha-Amylases, C-terminal beta-sheet domain
[ 154] -----11------1------------------113--------8F-18-2mYC---2-11-------1 ---------------11-------2------1---------11-1---------------1--1---12----------------------2-1----------211-3-------------------1---------1----2---------------------------------------1---1---1-----------------1-------1---1--------1----------------------1-----1-----------------------------11---1111--------------------------1-2---1---------------1-------------1--11-------1-21----1----1----------1--------------------1---21121------------1122322-11------------1--1--------11---1-1-11-11111------------------1-1-------1-------1-1-----------------1-------------------------1--1---------1--------11-1-1------------------------------11---1-1---12112---111-1--1-1-----1----1-------2-------------------------------------------------------------------------------------------------------------------------------------------------------221-----2------1--------------1-------------------------------------------------------- 46-2AB3-61--1-------------------------------------1--1--1-----1--1------1-----------------1-----------1----44G*******wrzuv*y********3***f*zo****oT***Y*lV**wm**U***i*dLnbZ*h**R1537S-IH2A4356-37-429339 * b.1.18.10 Filamin repeat (rod domain)
[ 155] ----1--------------------------------------------------------------- ---------------11--------------------------------11-----------1---1311------------------22--------------1-2----------------------------------------1---111--1------1-2-----------1----1--11------11111----1-11---------11-2--1--------1----------------------------------------------------------------------------------------------1------------------------------------------------1-221------1--1------------------------1-----1--------111-----------------11111111-----1---------------------------------------------1-----------11--------1----------------------------------1-1---11--1-----------11-12-----1----------------------------3-----------1-1-----1-1--------------------------------------------------------------1-------2------------------------1------------------------1--1-----------------------11--1------------1--11------------------------2-11111111---------------------------------------------------------------- 646BCGd-vPV8IFFA9ACFABBFDBAFFDEDFCDBBDBCBECBBE8CB88ACACAABBAADA47B67776676687496757573A9ACD79AD798988E7FFL4E*G*******vrso**t**j*v***D***azsf*kz**X*muR*cR*n*tzzfq*au*TK*cWpVdvT6MSK*88BAFfbp*8rW8Hatfgq * a.39.1.5 Calmodulin-like
[ 156] ----------------------------------1----------------1--------------1- ----1--21-1----------1--------------------12---1-----1-------11-1-----1---------------11-----1--1------1---------------------------------------1---------------------------------1----------------------------------------1------11-----------------------------11--------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------1-------4----11111111-----1------------------------------------111111-----------------------------1--1------------11----1-----------1------1------------------1-1-----------------1----------------1------1-----------1----1----------------------1--11--------1---------1-----------------------------------------------------------1-------1----111---1--------------------1111--------------------------------------1-----------------------------------------------------------------------1 32--685-mMT2fe*ACFDC9BCACADDDBB9BCDBDCBCBCBBAACBEECDECACICBAGB945346133376344123656544766ICGCEDLACE94BCaeY-2*lJ7FABD95896669DA895JvA4A9L5377C399477665B96C8C79743-462A687A-7378BFBIvPLNWN****E***oEYLN6 * d.61.1.4 Atu0111-like
[ 157] --------1------2--------2112--3----------1-------------------------- ----1----------------------------------1-----1---------2-------11------1----11----------------------1-----1----------------------------1--------1-2--------1-----------------1---------------1--------1-------------------------------------------------------------------------1---------------------------------------------------1-----------------------------------1---1---------------------1------------------------------1-------------------------------------------11----------------------------------------1--------------------------------------------1-------------------1--1-----1----------1-------------------------1--------1-------1------------------------------------------------------------------------------------1-1--------1-------------------------------22-11------------------------------------------------------------------1---------------------------------------------------------------------------1---1---- 34DDNPH1YEDGPQWJJILKJIKKOKKGJCIHHIHHEKJLFJKGIJEIIJLJPOJMLIIHHHKLLIML8ESSKFHTUKTUNFFFHHFJJNaLJTSPJFJHGKIdme6OeLx******oWfni*n**e*f***1***dknm*kr*tZqseltki*dull*YdXbbYeTxTW*MqZPAONE*BDBEMl*w*M*Sa*QTNOK * a.74.1.1 Cyclin
[ 158] 11-1----1-----11--1-1-----1--2141---1---------1---43-----2---------- --5-1----------------1--1------------2-1-519--------------------3-4-531-------------------11--------3-1112-1--------------------1---14134438---31TBE7676-----------52AJHKA------------11112----------------------------------1-------------------------------------------------------------------------------------------------------------------------------------11--------1----1---5---1-----15512---12-12------------63234243322-1-----3-111--1----12-1---121111111121112-11--1------------------1--------2151------1111124111111-21111-1-13221---11-17----31-32--5-211-------------6211-1------------2--1---111114C-----------------------11111121-1--2-12-1----1--1-1-1-----2--------------1----------------------------------------1-----------------------------------------------------1-1-2----1-------------------1--1111-2--222223----------------1------11----1---1-------------------------2-----------------------------1--1--1113-1 A969OTe1dIOEWOXDGKGKPRMONTQMMMMMNOJMOFGGFEGLKIJMOXNGJJFKGLFLKJLE8JKH7HKCGGFEFAHGAGHHEGORQHPQGOUYNCJFCEAQOLAYGb*r*k*r*aTfXWsc**N*U***C*v*QaST*Yo*hVuYVN*TR*XyplvTs*UtkZFsXivRWkoFWXM*HKLHMjDKiJSbACNdPPP * b.70.1.1 Quinoprotein alcohol dehydrogenase-like
[ 159] ------------------------1-----1----1-------------------------------- ------------------------------------1-----------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 8678CEF4bHb887D978688899888CH89677887867877IB887898789699577779ACAAB9ACBA8DAB899ABBB9BBDBGNF7GNS888BNO7EKK4FpG*q**u**qvxz*xz**Z*s***-***x**c*l***jv*x***roe*qh*G7Xi***6*Z*Tl**BA*oG*CCEWZnmVqUpNDPFGD9l * a.22.1.1 Nucleosome core histones
[ 160] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------W****rOY********F************r**UT****PB1A*---------------------------------------- * a.212.1.1 KRAB domain (Kruppel-associated box)
[ 161] --1-----2223222-13------2--2-J------1------1--13--111-1-1---11-11-11 FBQ4k--1-11-1-12333-32--21233332233316233A9GEHD-EE925A42-3--4528P39JK7696664992-13------MLfZ-H33---BW182gAG-H-----------------2-1--111-577DD---E3313433---11--------122361------------64122GF1437-----1--1-11112585547---1151-12------3k-11-------111--1-12323512111-1312225611225211133344442113333244333322222223222222332213332L22K43333312221R2--1442L-O112371111--129-12136L-1-1-9D666-----2-9A53256445511221221214-44752235263-A775AA6CDB78485-222-1222-22--------311--22-----------1--------------1-11--312--1-1-3555235111122641112123172223----13-6--212112---153411---------245-113232---2---1-1211211-121325N121----1-----121------2-1----3432-k8-9-32-1-1--1--1-1-11-22-----1-------35332214565444444-44344464444454444425555514-433223222323432242223334--234444432444--1------32211-5-42222231----11211111111--24V33236435243633645---------112241111113-6623MJLJJCFC4434--123322121----1-11-1------------------2------2-21-B7BDA3k71 --129BM-7312GFIZXnbiXWOZVZfEC7979BDCC77778A9A8UVRbbdljZaeWQTVSABE5996887B8IB859A7EBCAB578WkOXaZYB9DEFlPA9818*Kc9AC98C95477B9HA9J9n*N3GFK7769B8BCA89665A87H4BBB86AF5gdOA965IDFH615C2M453ATu***c*sDA****H * c.1.8.3 beta-glycanases
[ 162] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111-1----------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 561189Y-YCC2A9F8DEA8B9BDB99AA9BABB9B9DAD9DDCABCBCBDCHBDCHAACC986788829998AA99588989779BCEBDDDMEDDAA8D8DEIQ1W*F******usimlq*o**a*f***P***khYu*iy*tk*lxo*le*q*txmXniRWVTSyXdwOfTM2ILLSHIF9CREOF9KFXcs***x * b.72.1.1 WW domain
[ 163] --2--------------1------------1--------21--------------------------- ---------------------------1------------------------------------1--------------------1--1-1--------------1--1--------------1-----------111---------------------------------------------------------------1-------------------1---------------------------------------------------1-------1122-22-----------1111111-11111-----------------------------1---------1---------------1-------------------11------------------------------------1---1-----------------------------------------------1----------1--------------------------------------------------------------------------------------------------1----------1-------------1----------------------1---------1-------------1---------------------------------------------------------------------1----------------------------------------------------------------------------------------------------1--------1-1-----------------11-------------------1---1-------------------------1---- 1---omJ-411-KGK657B797877788758877765766566887666876A588697767866667447243676476535455A98EPF5LIKIGJFCEFYaY2Y6Wz*********v*****x*****P***r**w****vm**um*wl******QeppgXUP*WY*LocS1-1-7-111-1-2-7112124753 * a.87.1.1 DBL homology domain (DH-domain)
[ 164] ------------------------13322352------------------------------------ -------------1-----------1------1-----11-1--------------1---------21---------111-13---------------------1----------------------------------------B6242311-2212321233137484221122112122-------------------------------------1-------------------------------------1--------------------1112---11-11111111111-------------221111222-----1----------------------2--------1----------------GDDF-1---A7IKG459896A866566666569-DDCDDGFJ7CH-BEEAFFCKJGDABB8D786A74769BB3333333357723656---11-----11-111111111111111219CAB22896FBEFFGC746679AHG888868H9F9AB91368A499989AD6G524621228111111113425422------1----------------32238E---------------------------44743778C5C46866663757774866626A--12412------79994858886877778-8888877868878888889999883337667667777677776888777771-512121222222---411111333323847322413-11111--39899A8933572CEDC8C9F8A98A899A43333333315568444445445698B8A885662222232-551242-----------------------------------------------2-- 2133NRE-D5619A9GNGBJIIBEGDH548877BEDAB7B8774429EJSIKWLAADA8798B36335263736597277489878276HVDNLGD6476978FE6-B*R*QPIKaRMMHLVPKttGpK**V-gTsIHEJbGHeRFMCHDUH9aDIERLhoSCVTVHkYTSgsLo8HIL*DCADGR***5svFGWOOXS * c.47.1.5 Glutathione S-transferase (GST), N-terminal domain
[ 165] 11112154555555431211221252235244222234333332422223222-2233412222--33 5565D65744476597777-783388777777799979EE39763563355485766544675298A675745544332333754366554414111--34455554441111111111111115426643246456688212554335333333344444444353634443444444444444332224564544544464444456477564454445544333333564444444444444444444442123324-4-4422333333525443333233323343232333333232333433422222333333312334333333333343333222341124312422333322321112112445877833333579776649898866666666667-446446656783977B77A88B7776556767777767854555555645445783323333323--111111121211233333676637A9776666776787766678888578889CC9346647665697889B3376557854444444334868644224653456662555564654777799224323433333323222222135342447665643645476666797677686676774-42447-1111167885565554555555-55555555555555555545657766766666666666666667555555554555555555555115533333555557756554544233333444AA99A7644565AABA698AB67776988444444444535536666658465556555555533333341553355--------3-2--------------------1----1-111111113322 534499A1LA62779AC8CDCB8ABBB89A9A98757878A88AAA7A7BACGB789B888A8579794796865994796677856688D8CB9A798999DEGA1De6FBEFNEJCCAAE98FIAM6d*J-KCQ7GBCBDFEBDAAB9GADD9LA9EDTc7H9B9J87bKAFB9EGB*AACGDH98Q8KJHEA899K * b.84.2.1 BC C-terminal domain-like
[ 166] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 2222----2---------------------------------------------------------------------------------------------------1-*v*v***mkndo*k**s*m***1***m*ox*vy**Q*dTb*aR*l****8LMQ**D6DB7944**-**-----x--------------C * d.170.1.1 Scavenger receptor cysteine-rich (SRCR) domain
[ 167] 323223C7556556875622223583344354212222122213434952343245444535773133 --1141--111---44444-43--2A444442466626DE-1-2421--1114323-3--112425G4421-222----1A83--1-311---1------11--212-1-1----1------------11-211-1222111-2-1231112111111124112122111-------1----1212-1-11-5223222231212121112223311131----------2--322123333222331--23--3----1--1-111-----1311-1---1----1---------------------11------------31-11-----------2---111-----41-12PM2-2--416--------214442-----3-964--13413311121111111-34845948311-33242224424446212114222211---------832233-1----------11--243-3--1--1----12243125453A777792566688E68A896A64B7867-145534422512153242123342-------1--231-563136-2131-2-121421321112123-3-----11-111--------1---1155---2233-1-23133213325524342265---121--1----13311222221211121-222311121221122222246323--421311322333333235-1122122--33333333333----21212111-211122-22-2---------3453311-1-51312225534252315451211-212211113-----112113214244111------2-11--------------------------------------------------31-- 67353441E534355redhyfyY*s**DEHHDHEGEIJKJJEFHHHdNblv***YXaORNNOGJW9FF9CCCSEVOEBEF7IGJJN8A9LXJeEFKUMUFDAFUHW25GBpfiXWPXHEHGMSGXQFcG**O2aOeDIEBLHMTIDHIJ8PECdKTMQJHWWEOLIZqMM*HETG3559v465BFPTbmegL8CKDGFH * b.52.2.3 Cdc48 N-terminal domain-like
[ 168] 33-13111221211241321322-132224233-24213232456672345252636544332231-1 89B2j84D988223B6589-9C11AH888886B9ADQIKG2HHQE56398C3AB9219--UO83iFeSUNC622244451JH8-31-1A768-2321--19681A4F12--------------521C7B84DS213552125CF3O55E54B2144-2--2142139CF1-1-111112111422---11965FHEHJDBDDGMGBJB88CD6ED9I263A624B769C5H955557558687856742283K4927821824AD54EF55677289HB8A697687748765878867487756AA4556464432454462E44HHCDHGEECE46FSM754193373-MM36FGKH64365B2673131413TBCD1CB2K95CEGE878FA5D7564646767D-EABAIJIA8HC4G8AE9BFEIBGGCD67763F6764AB8777777778EB22DHP--11111211124-5512832122-3-4514AE918972B9ADHFCA4541AADAF6853CAFQ97A7-1C773A3F8LBG6DC4463345375776647944B14AD66278-2B3424-4E8H64N4C67879756211-1----2----------211-6324684A35653326DG36437-133647727--3B24B------79AD3688BAB8DAE991C8896EDA8DEB89A79A5797B5IYH5653767587547435977766667-664736665432--S68986753542-49632252353533F7524354645-13D678B9ED4B4DC792A57222223222246566B7ABC7255C4969675659779--92768886---1--1-B-2----1--1--1---------------7311-11--1742 -122-11-411-11---1-2111---1--------21------1---1---11---11----1-11-1-----1------------11-112-111---1-11---1-1-3121212--11-1-33121691-31311112-18--11111-13---131---3-11-123---11---------4--5-31-1----- * a.35.1.3 SinR domain-like
[ 169] ------------------1------------------------------------------------- ------1----------------------------------------------------------------------------------------------------------------------------------------------------------------3------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------1--1------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------1--------------------------------------------------------------------------1-------------------------------------------1-------111-------------------------------1-------------------------------------------1---------------1------------------------------------------------------- 1111jjW-2114FEJ8798888888898888987788888888888999999BA989ABBCBCAA9AA4CC9C9ACC7BC9BBB89ABBCHD7FEHCCCBBDBZXb3Y5Qr*******vxov*z**q*s***M***swtv*y**xl*xsu*mg******RmmqUTgOnJOsNdRN21212-11319CFE9D42177562 * a.116.1.1 BCR-homology GTPase activation domain (BH-domain)
[ 170] ------11-------1-----1----------1221-1--------1-111-------11-11---1- 111---------------------12-------111-1--1-----1-----1----2-----11111111-------31--1---1--------------1-----1------------------------------------11111111-1---111-111--111--111---1-1--1-1----1-111111111111111-11122111112-11111-11--11--11111111111111-1111211-21--1-122--11--1--1112111------------------11---11--1--1-11---111--1-23222322213--111112111-1-1----111---2---211------2--------------------------------1-11-11---11--1-----1---1-------2--------111111111111--------------------------------------1--------------------------1--------------------------------------------------1--------1---------------------------------------1---1-----1-1-1-----------1--------------------21111211111111111-1111111111111111111222--111121111111111111121111111--211111111111------------------111111-----1111-----------------------------111111111-11112222212111--111111111-1----1--------------1-1--------1--------1--------21---1------- 99CDHEO-Q9A2KJTCCFEDEECCCFECA8D9DDCCAECEBDFCDDFEEFDDCCDFEDDFCBDECABC8CCCCCACC7DDCABDABDEFDGACCAEEBCA7DAJML4UfN*******glkVa*m**h*a***F***elgh*cv*cVspaV*Ze*izrmqOWhZZUUI*UYORNWL7KIF*FGH7GdctyEwMECDRFHC * a.5.2.1 UBA domain
[ 171] -------------------------------------------------------------------- ---------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------ 488C114-5--------------------------------------------------------------------------------------------------2--**********y*****x*z***K***s*w**y***b*xrd*wd*y**********LIeHP*d**A---311311-------2------- * g.60.1.1 TSP-1 type 1 repeat
[ 172] -------------------------------------------------------------------- ---------------------------------------------------------------------------1-1----------------------------2-----------------------------------------1------------------------------------------------------------------------------------------------------------1-----------1------------------------------------------------------------------1-------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------- 77ACFFR-O888CCPBBCC9BBAAA8BDDDEADECDCDDDBCDAABCDCCDDDF9CCDDDDDDECBBC6CDCACCDFDFFBCCCBCFFFGLMBGHGFFGFDEGQMS6KY7m******noijlrj**k*j***A***fnng*gt*Wdsqgh*hb*kynnlTZxfXTfPpQTlkbRN9GA9tEFCDHMHOcDZBKIEQQMN * a.29.2.1 Bromodomain
[ 173] 112-224233343333312311137568214711--11----1--1----12--4322222-1-1-22 6AC8M7AC88A664FFIDD-DI66HMDDDDDDJIGIGMRM4GBF2449222246644422ACE5ACEDDD922222221232922332777626322--444667466622333322223333355667446664ABBDD22274632344332332224223433335322332333322266966222467555564544556454787776455696982233333394333433323433334233454-342242-3-4433233222222232222222333222223233222323322222232232222222235422322223323242333222632--6664222526329423353342634DAAD2222247IBB875CFDDA77667554578-66A668666BA267767478797677988767676667B22222222433327AB2222223322-2222222222222222222889636A85778756565555666877772866BDHGC44BC59B868C9BDCJ57A32228422322222227884J9843322453322868774636BBAB89432233322222222222222223322326424625495544444445444464454462-24623-11---52542422322222222-23222222222232222247452352335333333333232332242222222222222222224222444444788926622222423223322222998894476462BBCB5A98956466679232322323233342222257255667777756643332263443355---1-11-4121----------------1-------23322222222634 2222988-J74388C4885C89788697786554659767766999966666B855666658522244253422465-553333443325668766475654AFAA-9L8KBEEJLMAAF9AB9LPAVC**I-ULV8ABCGCCGEACCBBK9AMAJGENBLb8JG99B85BJEKC8564*65688E57J9CAACJD6EG * c.14.1.4 Biotin dependent carboxylase carboxyltransferase domain
[ 174] --1---1---------2-1-1--1322--1322132-11--1-4613542436----1-11111---- 2112--2322431-13344-462292444444B4654645-24414112112234-23--3223214123232221222-2-2111123332-311---2221212131-111111--------211233122-212233---342B645652222------4613C631------------11133112311333333632323432211111333121311364444432-22121111122211--11-75315611527331163211331445222111122211111111111111111111111121122211123-235444447455528665352823113--133431323--133632111225221-----333272-53343111111111113-34224635334-2111313314255723-2-254341--2222222231--1221-------------------------------31--3111-2332221333322234444244233535-13432233344242152521214412-----11332421321-22231224-22242532324412552---1-1-11---211---1-1-11167344-21-11-212---1111--2-1--11----2427------31222423333333333-333333332333233333246422111333233333323332333322223--433333333333---1-----22316-51------1---------2222223-1242333434332233222321121-11-12---1---1-11---1111211111------1222--22----------344231-2121111111-42111221112---2---2-32 68A9JJC-XCB5MMNEGHDFIGFJLHKCCBBBBFIJCFEFDDDEDDIDIKJLPRGFIJHFGGBBCCCB1CC7DBDCF3EFBDDCBECCD9IFGEDHCCBBAGFWTS3IGVNcjTodaLRPJQQTtgMsR**iC*X*KNTLYRQkPARQLKfLP*UcNRbDU*PCCJCnFJtLbGA9GBD*977AASOTyFZPCDUgYaE * d.220.1.1 Metal cation-transporting ATPase, ATP-binding domain N
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fBbCN*L1EJdA87AK8BH698796899M9D89B8CW8DAC8C9DLIAAAA79A*BAB9ATHcS8LD89CB8E9 * d.14.1.1 Translational machinery components
[ 176] ---------------------------------------------------1---------------- 731A7---111----3322-2A221122222-54442532ADAJj----1--558-----862-93C5543----1----A168AG87---1---------------11--------------------------33333---34WLFECC11-99---3--8E5-77B3------------B-41----882777775672777777122233777564B2EC33333376---------------------233--5----5522-1-14111-----------------------------------------------4554A33322325361J774343511--3775176521---211113---6237AA51111124RII868IFEGL44554553546-NKIII8FO8I51GFFGLNJMNNEEE7BC82A27A55782--------DAA5-R8K--------11111111111111111-----8A873A9932EBCCEEC8786DDPTBBBB88EIU9GCO--IIEOCLCDN14U55GHLKIQWPI-------98ENTV147346AB5BABAE-878H793FC111121-2B6641-1-------------GEGMD53NH9TPKVKUObTUTTWQUMSSSRNULKPNQ--1CLCQ------JLC67JAHGGHHHJIHF-DHGIHFEHGHEHHEFGGHGKLFBB---EDDGFHGFEFEGFFGHAB9788CB2-B66666645666---F-1-1-CEEEC3dBN---------------456551412-BPLMPKLUMOOLLKLHLNN-----2---NCKIHMLLMLSUPXWDDEEFEECCF3333--J-AA6489111111112-4-------------------------1-111-1------- ----21-----------1------------------1-------11----1-1--1-------1-------------------------1----22------------1-------------------------------------11----------1111-4-1-----1-A1----------1--B1----6---2 * c.1.33.1 EAL domain
[ 177] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGEIHGG-*OJ7EAPA9C9DBDFEAACDDCEEFC996A9A7ABDEFFEEFGBGD6CGBACBECECA7C48BA9A8AB7BB89A7A7AABHIK9LLSKGLF84EKTO6PlBl******nccdjxi**Y*e***G***ShVT*Vp*oSooWVtRM*jvtxxGPJUaYLGiKLcW*UD7LQF*JJHYJ****C*pIHVWZZF * g.66.1.1 CCCH zinc finger
[ 178] 33314244444444654532242253345562345232111211311111322144344341112-22 87E2B32355512146D33-37113D333332755588A75A468A725854ICG31911A987BACDEC723334346212912111447717-----3614553D241------1111111132322222232CB9CA344885444553222233354333253457434334443343C8634563437666665592666565957756664359564555454478456565555555555456748352673343535339A525334353657554533333333343333344444454543526511154463746A666876876967--488753C6444411311111721446545344156665-----53C8A333765675545454344A-215114528I4-DBBBA9EFDCBA3435369AD9BDB772222222285635334--------1---1-----2--1--1---123342124434CBBDDA99788BB9BBBBB9BBBD44532278842422669558113252354111111122433245422143226222244423332254445514112112122112111111124111-4478A616118455555567665645465565--241331--111EA88998CFGFCDHGCC-EBCDDFFDIFEDCCCBCCAGDG6999AG9CDDCECCDFDGDDFACC9CCDB4-999999978A9A11223333312113277A6558571344355652223213112845555497954445565A3223232223578C5666677779656555555522221138222233111111111-2----3-2-2-2-11111211--11-49755496664933 -133897-965286977967889A97A7766666575556766565747BD7A8676B787656434446456564545433554457655776A86668687B75-5Q8CBG8AC434435A575284Jl8185E35348559446563964E4844A5685A997H6DD4IB679BAj995C9SGJc7RJ5BAC8BA * c.72.1.1 Ribokinase-like
[ 179] ----------------------------------------------------1--------------- --------1------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-------------------------------------------------------------------------------------------------------------------------------2---------------------------------------------1--------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------11---------------------------------------------------- 33-18A51N9E-5572252223222232222222222222222322322333422233333342323211223322212232222222226323332331231BAG-7HG*******xu*s**v**t*****6***m*to*r***g*uuu**u***b**ELeCKMGAPDHhPJQC4562813146A268394328JCA4 * b.29.1.22 SPRY domain
[ 180] 33-1--2333334544122222-4I55545D7323--3322232532224766113--233112---- 2132224467643332255-581172555555655852762228533442225232431133625253622-------33336151113421-4-2111282A67A534--------------2323321-232-544552223644873333323222211342369531111111111115E5552--76444434484444944464444444568544333223225434445443444444437448411111121-11111114111113335222111422-----------222222222222223322233344AC6B8888888585548755545-53555532F86724464573372334335119-----4411761C418115566466366D-6643C894D38-177732A6226928232B2654553333333333333342424-----------------------------1-21324444667768545666B96356662677E475I25AE4473IFBC8654B7E67435533455445D6657335333353455562365244327332266444443322222244443444425131585735B43722444333362933E2322B22---462C------23444343333333333-3333333313333333333435444445353575555575335533333332-444444444444---81111-222374333333444-24561--36456744455A758BG555666669A4441----1---24546444446534452--3---------1253553322-11-----216---------1--------1---11144422333333613 ---1B85-732279968BBABABFBDBBB6A8ABA9CB8B9BABAA7A9ACBCDAAA9A9888785652742778453357775772226A98374322433469F-7J4JTIFLER8ABDCD9SaDQ7z*S-pYs8FAAG8HLFDHA8DNC4*CcODI8Ir5D663667R5B8J2A7Bz537A9**t*C*j64IQKHE * d.58.17.1 HMA, heavy metal-associated domain
[ 181] --111-547344775442452-29C35A9145-136648899B74-384IQQH-87968833345-11 5EM-612454423112311-14--2411111344443634277752614653C49333--6821D14KJD532222221-212--2--33D5-411---26133IHB5411111113222222311--1--1-4-9BAC8432E174964422222312111132J56A411121111122175523---53553556546638445423333354523244534443327D111-1-------11------31-1231-11222113412----4342224424211244435443431-11-1232-1--221---111156344111-1-12117311234333A419461-11-211321445231223-9111------5548634443553------------97779565323-28A3423342351-32122344551136666666624624436----1111----------1-1--------112222-2221311-12-566611417765542124346--779324-1941251223322281111111132344145-211211-1----A78678I1247D4Q82A1----------------------1-22A9271D7-524987AB333665554335171-231-1------56534546556666675-5667566746565666666998333318857788888878778744466652-444464444666---2------1--51E32111221-22-123331111111-1-4I5484465383334544533313332317BB9CFDGDGC9DE645555622323133-2-22--11212111112-3----------1--1111---1----14121211133Q-4 32-2**I-C4216678496436673656622225255566454445D853B99876965657322322-3223-333-25124323311A87476A686447967D-7Y8*UVLUJOKFIKKRKrdKXF**T7eLhGHKGKHMSODRMEDqHE*DGHHRKEt5HSJDHEHN68KB5MMG*GGLD6UINO8LH6K8R88B * b.1.18.2 E-set domains of sugar-utilizing enzymes
[ 182] 11535535455343655234435456844466333453533333356515354634455453244134 5942633455531265422-25115622222458684452375544244231233341336622437672142333336555A2122354642434F--37455C3554---------111113332323-12823235654294636833345552324335536455325332234232246444653355777777788777898CB8856798366859A99AABA9B86666666666666656667A68488596669A66888698858677777577667555566555655545555655555867555555659478888875749453663776D663349AC3GE959A567413655536255436333334479A3447555833333333335-87687898465165576757975635555335764435844444444245526461111111111MS749856E633455222233454434349799A9755554668C555544A684758335453577385455244525437412111113447587F8887B65BD88A8797765ABG66566A8A42214222221212222222432155476A68444B6558566555855565656761-3254611-111767A5687777786966-86667686778975675598788867666567776766766669566566571855566656766114122222445454A4753446334333343455565566656678987B786677655773554365454655C7587576766243445432243331185443322111-1--151423333---21-13111-432122226C775756762624 21--554-D544795588AA9ADL8IBBB699AA796868677977B7BKF8DC93873CCA612263235323335223233333122575845A555244765216F4H7594523574464763A4De6-B5B2543643652344364185445976379731A55346774878w69779AABJ8CC5976555 * a.211.1.1 HD domain
[ 183] 22222334333333332333443245545262322322343324434332434445443452323132 3583944555545369944-47336A44444687775676442443544445867439226553748898322222222243524222656516332--2534353533222222222222224332232223334554422254355444334223232223425445522222222232254333333334777777774777777654454778456574433333396333333333333333333334344344333333334423234344422332333333333333333333333333333333333333333243266667687464473355553232243433A945233344333233272322242222222543332324324455455455A-333332448G32AAA6668897874233339A55556772222222232232232222222332222222222222222222225335423333377788854444885976775688A25342233223222433346242232263222222222232345435464235333354634354465657343221222222222222222222222222334635667455333354664436365357112322211111153543844444444444-44444444444454444446643344534333333333333335444333332656566545666111422222333322785333222222213222544463322222556557544877625442222222223222222222333224555555444333322243322332222222222212222-222222222222222222224322252222322 7666AAB-hA96AAEDDCBEEEADGCEEEBCBDBBACCABADDECCBCBCEDFIABBBC9899AB8787A87AAA887899AAAAB799CJBDADECACABF8GFI4APIbHFGGFGA9ACABBIG9N9Q*A1EDKAB9BG9AGCBAAB9C76PCABADALMDCAGBGFGNCFIEABFB*B9C9AYFLUCKN8BHDHED * d.127.1.1 Creatinase/aminopeptidase
[ 184] 22142653544554451233322BoHJZPQbl33522111112331A7459EH212564623333-29 A5A57756777756988HH-HO11RRHHHHHFQTRT9PaN2A7394A34112AGJ948--FAJ4AAe8K8C4444444-254I668663334-322---295FD928M6--------------1942A8B7977B666AA4468CGHHGGGAA888544453EEAGIHM5-1-----1----64377---4223333333333333334222124331216243544444523443434345554353453352A24425222BB553364745467722212221111111111111111111222111112111111111-321211111111111244--1-1-1--2--1555632--221124---18ND722F211118486C967DC9A644444444445-BVBAIC8MCA8-6658968B853A39433D526756C575555555523332996------------1111111111111------415-49927N88F8GDCBC6GGJREDED2E8HD7LNK23BBA7759C5AEBA5C58524138112222166764687RF3IGB4CAFFG16455453758AE8BDAZ21212-----211111111123---446595D3648287644467C666A74C9CD7--18EC8-1----86549957778777777-7787777777777777777BA8445597777777777777777774766773-533333313333--1333333742546786111434143442334A567828555E3DDED68C5AIAHE96443323233232775A66666576564422222111------2-331133----------1-----------1-----------------------2223 ----BB4-21--77F32221333122222333323333122333333223233222422333433-11-3112331211--3343222214223323223123DB9-4--1----2------1---------------------1-----1-------3C97ESD---2----J--8BD9785GAMce*2yL1-23212 * c.26.2.4 Universal stress protein-like
[ 185] 222-1-2-11111---2111111263311323335213433327524644797--1--1212322--- 5112112666743222388-8D22F5888887D86B557523364325611143D235--44523183642133323342534232143333-311---1213-4313311111111111111-2323321321234455---372DB867544221111115522C972111----1----14222112432555555754555665241122556462331564444434133242212233322-2112A9348A4374A66337745433378A3222211533333333333331111111111111533555333223246555769686748774352A332342224644332232244633122329226-----64449716637431111-111117-5942A946845-4334327612367D231A1554562223333333344211434------------------------------2614-543332222222333344344444345572667-19A3423CA77165364C341254--11---25533941332133152546-323545456344248732121221221----1-------1-28A323341-32121111122231132111521---3539------42422413333333432-3333333324333333331565222-15353555555435334322222221-422222222222--131111-34659231-111-1--11111--1322433333163445666563467463451111-11-14-111222221--333311211111------1232--33--------1-425332-2221211111-22111111--2--121115242 3445BAB-N873DCG9CDDHGGCHHJFDDBBAAEEFBC9C9BBCDDECEHKNPSDFIEFCDC747686-68466889357778778A88AKBCA8G99968AEQMR2DGHCVbNXVZFDDBIJFejFZF**a4mOwAFBFOCJPI9JFIDQE9fFPGLR9KoL97I7cABYLS895FF6*8879ANNNpFWMCDPcPUI * b.82.7.1 Calcium ATPase, transduction domain A
[ 186] --31-26677786775-444234284542253331544334332244333635224242-3344--45 78A5A43433454451244-47448F54555686777BEC25486433353324532222347465D968454443552463734545665415221--554479375711111111------144455454375566561-2777475444335545544555467676556444455444645664446663333334434635547877663345654A84355556A955556555555555574476645357453438744757654634443333332433444454544444444444444444445333444544235333644323296553233535112444399367335234445124542655744544759665344443366675756567-446445654754A889AA98698778574573656598466666666633344642322244422---------------2222358833675648999A989777997B888887A777A8766788787A77BA68754766567544333434336874433365534333534754744687648564443222322222222222222333333355637566B546556545555564445544412453511111165858568897878889-8788877879879998996887885558766786789778768767877675556666666666622354444555545656755563432222333644544475565479974887987865854655554455675544444444565446555677633334453448877--------311------1---1------1-------22312334224643 1111554-632-4479DA6HFD9FJEFAC9ABB8876866566975D7AFEKTK59A78777A8A565484677B773776A9B78794EL8D88788748994A9-7D2A5846685633756782I2ShC-F5944325549143343C4274A556AFN5A767975AG8836556z56465D5AE47B4865445 * c.30.1.1 BC N-terminal domain-like
[ 187] 44114-21-1--------1212--111-12-1--111--11--11-----311-----1-12-1---2 3332422233323343422-223332222223232323322232224222222232332234322233444222223333323222323333221232235243423233444544222334431143322225233334223334342456112222247322333254233222232222321343322331323322323432623233363342643245222233332323333233333243543432322234222335533232232454122234322433333333333222232222222233222322235345222234324353434342333323223323334223434223532223243322224323644634553343333333423213222232233423332235632742433323222224424444444422222242224332222224222223222232212243223225333254433412222223222223255422332334423322331122222223222332222233373236653223354446354564456643347744324534344322333343243522321443354345244443443255433235334122622212222243354223544434434-44346444444443434443233354434332332222333332434342342334444434444223312122656722453444343321222333333534522424564535523323422322232222225224224434343551243334232234322333333443332322222323321-161-12111111211111133233343523543 55129B8-LE97B9E89DD6B88765BAA89A7C784867966CAEB7CB88EG89BA989867986542897C5698576A98456469B69E6447571G989F2AHLUgaWhrSEJMLGPLufEpH**n8*g*KLKFYJKTWGPDEKbCD*JUOUQCLTBDJ9BXFNJCLD97GA7d86667*EEI7SU8A9DCA8 * e.38.1.1 Release factor
[ 188] --------1111111-----------------------------1-2--1JO7----11--------2 -2--1---------------------------2111--121--11---------------11--1-1-11------------------6712-3-----12--224211--------------------------14411---6--1------------------4-----------------2---1----1-------------------------1------------1-----------------------------------------------------------------------------------------------2122332-2-2-11-----11--11-----2------------1-1-21--1------------------------------11-11-1---1----------------11-------------------------------------------------------------------22-1---------------11-----1--------------1-----------------------13-------------11-----------69-----------------------------------2-1--------------1-1---1---1-------------------1-------------1-----1---------------1---------------------------------------1-----------2-----------------11111--------------------------------------22222----1--11111----------1221-22---------------------------------------1-------2-- 8832FJN-F73642575876654463744446636577674655465764568B38E7778B421233115232-564662-112433349352474345446KFI-8ZV*******lkskp*u**g*j***L***jjhg*dx*yjunlm*ca*l*z****oi*mMFRFCbFIwH7688T45565*cch7**4EAOCBF * b.68.11.1 Kelch motif
[ 189] -------1-----1---------1-------------------1------1----------------- ----1---------------------------------1----------------------------1-----------------------1-----------------1-----------------------------------1------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------1--------------1--------------------------------------------------------------------------------------------------1-------------------------------------------11-1-------------------------------------------------------11------------1-----------------------------11111-------------1--------------------1-------1--------1----------------------------------------------------------1-----------1------------------1------------------------------------------1----------------------------------------------------------------------------------------------1---------------------- ----JJV-3--378E332543356655654434453333333323245565656434445554232221223112321222324122335743753323123696E-g24********u*lz****r*u***O***r*zr*w***d*xkr*wj******NfxWdZRM*UUyOqVN-11-8221126125453--55451 * d.15.1.5 Ras-binding domain, RBD
[ 190] ------------------21111----1-------------------------------1----2-11 -1-1-------1--JAC66-6611GD55555365551-1--1----2---------------1-1------1------1--1--------1--1----------1-------------1---------------11--1----------11------------1---1------111----1-----11----444444244454444-222--44911321-1------44--------------------------------------------------1-1--------------------------------------2113343131113141---221113-1-----231---2-------------1-----------11---1-1------------1-------------------1-1111-----1-----1---11111111------1------------------------------1--1-----------------------------1----1------1-----11-1----11----------------1------------1---1------11---3-----------------------6-1--------------1----------1----1-----------------------------------------------------------1--------------------------1---------------11111------------------------11111------1------1-------------------11--------------------------------------------------------------------1----1-1---1-1----- 4434MFN-J7A6EFMACCC9DEBDACABBAA6ACEBCB9A9ABCCA89DFCBBABCDCCBBBBBCA9A59CEAAAFE8FFA998C8FGGEKFCGGEA99BBBAYXa3WRBW******ebSQd*X**d*d***7*s*TXac*Zp*ZTmaWP*VN*h*lj*Ru*YRKPFyLMgWiKH6EB8*76667SPQaCjH7CbfhgQ * a.29.13.1 Bacillus cereus metalloprotein-like
[ 191] -------------------------------------------------------------------- 434-8--111----4--22-21--15333331--1-1733234472222553AB75CA--1182716886111116311---223856775729661--7JG894FC563333333444444442123342222544474--195112-223331133343112-12241263222261233ABD4411-GAP8888868A8888A888DPPET88ADJIJD29DBBBBC9IC899999799999998777AL1636529111BCCC658D756888A2321111423222222222221111111111111333133333-6LI718A8998837353889222E8H--D54BAFIPBF3Z839CCC6-1-4514552-1111223432111212122222222224-11212212442-466333633355-12-12221311238--------1--1-423------------1-21-1----1-------213-157777A9989877AA78876BBBB699976676-1778445556434644594757A5456666666255348864A533O43333ACB8ED97C6546JFCB122211111111111111111222488CC68877679D99AAAB8688998877977--2D88A---1-1676966989A7877767-9788A8878798888888777C7733777778887888575789758776741877777767878--375645486776985A333636322123224BBCBBDBBBB48989A57659555578781111111114DDGECABCBGA9CB665646645513233-1A55334488898899C6--------------------------22333222224945 ----754-623-26A985BZFNEFJCM542222YgDD74736621159GaAMPMFEBM9F89--1-----------------1--1---B7987433323--38OB-2624685846435136496382FY5-8594125614A6352156248265672-334161I3335I431GM4A755Z4ZJCh6KS-254553 * d.7.1.1 LysM domain
[ 192] ------2444464442-1--1--2---1-1321----------1-1----1----1-11--322--3- 7AW1C545666744LKKEE-EF22GIEEEEEGKHFIEHUO1A5HB48-1331675418--6394B68379222225542136----1-3396-721---4925BJ3K16---------------21-11-1113344344---A1343333112111--2--21--4171------------456111113155574724567675435466834441117335344445962666666666666667777744524522423543355112636322333233346633333322322333333333333344411134443-12311111122116133-4437-511356--21---1-------31-99-NB554-----13A8A--242252----------4-88877D684A8-D5546438A8647674624531332326566666682234144------------------------------4886137563AACDEB89BB899A6BBBA5AN9E9996-287726444925482141-2-43-22111-1--113434222--1-----1-12------22333DK11125--1--------------1--1-11-12138435115396376455534445466-------------3557231345636654214344246524454333333356441224424444434544444A2223332--233323333322---1-----132114512222516----132217778758134368656435543327-5642332333231---222122322--465A79A4532111--1222--11--------113--------1----------------1-31121113-I26 ---18B8-A52-46HVQaOZOOZgafgEGABBADE8ACA99ABCBAUNFYYq*tLPPXFGGG4211121311723-1111155483145EhOQINAC8C77AJIIH-6wKlABE9B897885FDNJ9A6L*A3CBF84A9B56B737785975G869B96249EF76A56ACC8654C7G34545H***UPS6CNIOTC * c.69.1.2 Carboxylesterase
[ 193] -------------------------------------------------------------------- ----1---------1-------------------11-----1------------1----------------------------------------------------------------------------------------------11----------------1------------------------------------------11-----1-------------------------------------------------------------------------------------------------------------1111111-1-------------------------------------------------1------1--------------------------1-------1----1------------1--------------------------------------------------------------1---------------------------------------------------------------1-1---------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------1--------------------------------------------------------- DDAETVR7lEGCROPNQTLMMMMLNKMMMNNJKOMNLNMNKMNKILLNLLNKOLKMMNNJIKICECDE9DDBDEDFG7EEDDDDCDEEEKdLQNLMJGJKIJGMKP8OuZ*r*jiseZUgZYiZ**X*X***2*n*VZYZpUZnYPYbXVcWblXfaYZVdYVcdROmTXeOThUHNNJ*FHFPQeiz*MzcGIJKILO * d.20.1.1 UBC-related
[ 194] 115642989A9999A83756556332243434566464655444435334546568464353212-22 6373833444444377766-6A446C666666ABBB98CC3A7743523334454338228943787787354444442363634443535644222--254856634211111111111111153335534385533883337395994453344444435356455953353433334365334343347666666766677677654665666865544354444448523333333333333333233232344342325533443332315553232222233222222222222222222222222222333222244244444444354524552222524225444455854248455546322445533422222357893333538444444344445-997A88995E427666768777CA6533344466555564444444443346A8D2211111111---------------22227566535774699A9B96AAA99978BBBB79A955675235547574445684545864558633333334649A72556448A466664375557567777676DA67425233333212111111167454435556548565655555855655586555562-3A76911-11155565555555554555-55455555555555555555555556555554454445555456555555563555555555555--3344444445593A35333434133324333444444666554885A7558857565979555456555755567777766888677555566544444493334444--------11---1-1--------------1-----33343453334523 44127B4-61115679998888898BA889878898676768789887687865768976666876773765666995A86767658895B79758A8887D6D8937J5C998797A474556C7386LV7-B7F565564799667666658478588Ed59657H69E9C978899*CAAA6ZBQP9JFADF8547 * d.153.1.1 Class II glutamine amidotransferases
[ 195] ----1-1111111111-122222-1--4---------------21-13-------------1--1--- 13B3F3333333335DD99-9533F5898889678793E84FCJ4763634887A333334454434CB84555555433373-----1162-311-----1--1-1-1222222222222223--------4--DDDQT---E3dFFNEDBAA22-1-1119BM6FDDG-------3----2-1--11-------------------2211-1-----121--------43---------------------------------------11------------1------------------------------------1115311111113112111111121411-141-22222----2111---53-B----------2111----------------------1--2--12--21111213221-11-1--312341--2--------2--------------------1--------------2--121-122-232222312332-173333312215534------45523435353228-231------------86693-34------1111---2---1-HHDHq*-4-1----1-----1----------1---121-1A2-1--11-1-11-----1-----3--1-2-7-------1-21-2-11--11111-1--11-1111112-----1---3232111213212222222121---11-11-233343213343--13-----------9-1----1----------111111111117332311115111-2221-22221222-2121111113321111437335541131--2-111111------------------------------------------------2- 5767OLF-WDE7CBLBACABABBB9BADEDGHICEBCDADC8BC9BC9DFCBGCDDDDDEDBA8BCBC69EB9AAEGCFGB9AB9B887CJCAABFC8A9778JMN1K*CtfldwihRJONRQO*nI*L**jC*d*KPNKWKVbPGUPJHhMLxPXLRXHTVFYTNEeJKG9IQK3GEGfCFBFCJJUSDNB98NPMMI * b.26.1.2 FHA domain
[ 196] --------111111-1--------1--11-1-2----12----1-212--21---11--1------1- 16E-21-1------111-------------------1-1--21-2----111-----------11-1-3531111----1-C2-3---5751----*--82-13821212222222--12111C5322-35351223347---4-99736533-332-1113332-5674-1-1-111-1-111344--51--1111112--1-111-1-11--11----4---------1------------------------1--11----------1---1-11----------------------------------------------1--11111111-11-33111---1--2--4-613---1---------2314234423323576E68754554444434443435-9A997689477-C3355444A47846376242211212-6666666635A54852----------11--111-1----------12474K---1-8AAB96333333321443424A5B3355--54551222461774--5232621133342273776436535--449755325934448235565Da1677A13113311AAACBABBA512256664232582426477A85647767F583765--23846------3--311-533A545253-258662563622624532811134344A2C7A2CABB98A87A-3326695---22212222111---48B778DCED31627--124315268343254946244633-AA6857357454623662122221212555533333444642213233-------23R2111133-1--1--141--------------------------21113312114BB- 4422KG8-G884PIVEADBCHFEEDDIFFBDDFECB8EEECGDBBECGDGCCDI8DEDGFFGA6AA95566878B9D3BA766699B9BDL9A9GSB9CB89B*yw5Vj*qFDBBBHFHDGMHFgOFRDj*N7TJfDIEEPGINHEMGDGLDHKFDJFDBG9AIAA976EG9AFc6AB*jCA88EJACPDEF7EHLML* * a.118.18.1 HCP-like
[ 197] --1-122111111111111121111--1--------1-------1--1-2332-121-111---2-11 1221211-222-21-------1---1------2222-211-21111---221111--2--2------2121---------2-11-1----1--1-----1-1--12-----------------1-----1-----23332---213123---1132---1--1--212----------1---111--------------1----1--1----1----------1-----1-----------------------------------------1----------------11111-11111---------------------------1-------1111111--------------1--121--21--------133112-1----111-1-111112----------3-34343323--11132112----332-111-2--1-1-112222222211111-1-----1-------------------------11----------------------1-----111-11------13-1--11------2-------------11--2-12131111-11111--1-11-12111323511--1------------1---1-----121113-1111211222223332241222521---1-23-------13----1111111221-11122--111111111111-----------------------1-111---1---33323323222--------------14-2----3----------2222222--1--2222121241---21-----------21112111111211121-1111---11-1---111-------------------------------------11--------1------ 4566WUN-nKN8GGN7CA9899B7979BB7AA89BB8A9A8AA7AAA79788A888B97ABACCC9AA8DCEDADAB7AAADEDCD766IQFCGGIDDEE9BGNMK-I*j******sdfahgof**Z*e***6*u*WadaxcjqfVkbYUpcX*cyoppLXVjcVUEYGKtNWVK9KL8v898GHTLWV9SZ9BSYWXQ * c.45.1.1 Dual specificity phosphatase-like
[ 198] 33131354557654655177754871135355325544644455558A52775443235651221--- 38A39213332--168766-6C--7A6666639BCB669B543643323---5561-3--438354A6D73----1---8cV5578572223-3-2-121421352834--------------331363713343AAA75433763633223111111121111143223-------1----542552213-73333334323335333366263323441--211111133222222222211222311211--11--1---11-111---1-------12-1-1-------------1-11-1-------1---------46714222212212115222443121-4F-244*u459B-AAB111521-44553341111348E8A83C9F7D84445444343A-A9C9AB9G9711788867669877C942374B7A7874844444444955-5E341111111111111111111112112111122553-48749C9A9ABA8BBBDD9DCCCD6ABADCFFA259A879677B689799765765592221221312FDA3IJD77ADAEA99E1EFCFC7C49EDBA7CBN9DF66769A383643323348J89844A726467-5-4B8DDB4ENDGHBGFIECOD1--4A53111111KCC9DG4HJJHHGDKII-GHHMHFGIHIJIHEIHGHDDDDAA53EHGJDGIKHIHHHLIFGFDBBFCCD2-A8899AA9A9AA111311111111184672BABCA94646456684444423344438889978466A89B8861111111113798E34444BC8795544646343111132A2554466--------1-1-------------------------12212121-15732 ---11-3-7533332565425A2756244443333222333325331252996546863566322141131-53211-11132234--1365634B2323352638-441C344734322124233262BQ2-8323321441362224121475781B2846A83382211A511122N233-2B37J282253444- * c.81.1.1 Formate dehydrogenase/DMSO reductase, domains 1-3
[ 199] ------1--11111---------2-----1----3--1-----121--4-773---25351-1----- -7I-b-----1---41133-321166333323767656QK-CFG27-12111121-11--973-RDHEDK4-111111---1--411-DCG81A346--1G38BR9717-------11--111D-1424---7E2DKKBF---*-NCH577F----12----4418NRhd------------B33111112-42222213652755576655B3321-1-32-1---11-72--------------------2------1--------------1------11--2-------------11111111111111---------213A2222422553624223212-431-2152-3211-211--1261223834---2-----22A13-1-11111------------1----3---51-1--321245332-126213---1-1----------1--1-413--------------131-31--------1---6-1-1---3----21------34------6112774--1--361--1-2432114--11----1----212---1C61-221114--22-122--332--11Jr1331-1----------------1--111131252151712737446776344548546A---1-11------11--11-1112111111-1112211221112211221131-112-213131332232221321-21122--1222222-1222---7---------1-B13111111-----1----------1--22333312524111122-1----------47734443466766--2111111-------84221133---1-11131--------------------------234-11-121-346 2222DHK-UDM5BEH7785G9G4DJCB678767E9B6A88965244I67GD9KDBB8E77773-1-14-11514-232224-1-214234KH7U4*11231349C61FLN*XgSVQNKCGDIPKtbBfG**f9iV*FKAEYDPPJJLDGDUEChESMCWUUTKXTD89AEPAL**39J6t6A733UDEV7NKcyEGGFK * a.118.8.2 Transcription factor MalT domain III
[ 200] 221---43666666551553311-697788A5--411111111-4-33A-53---11----322--67 3386689CFFF694866AA-AB557BABAAA4BDDF9EHK575865874A73F8B5772297719599896----1-1--12B543462331-244----636692884--------------2--13-3--3-1A8888---A6A88A66714664432435343B8B7333433433343C6899---6D599A9AA8A5B9AB99457765AA98B6B8DB42222267566625745755656445234121111-41232112112212-4353333---321122323333442222222222222222112222427423AAAAA8848318111776711232243-89437-1-2---12-2261895541122284BDM3542446444333443435-64344555C53-866245354487494666688B88666666666668225432411-111-1--1---21-----1--1--114445356GF68BBBBBBA6665AABC787727BFNCA7D5ADC377664F6H7DB476833244222222232136A46H5D58A-675451A6A65BD536426544A513--1111121-11111112375744647636525545578547777667765675--14954------756697789A9898988-A988999999A99888889CDE553336555565555565656598644482-455555555554-21443444332258B5724433842123-3216555556352BA9A695D6DC7D76AECC645344434B467B77777AA55524444433331-----54AA4322--------2-4-11-----2-----------------1--------5216 21--455-G7527964444666768546543-353535352455674653859C334225555335453364634466464333245455244443665331668715G9GA696463454675AA5H7fsC1C7C3454733C666521D2675836D7543WCD27484GH9658AG*EACEAI9DE3DADA88977 * c.46.1.2 Multidomain sulfurtransferase (rhodanese)
[ 201] -----------------------------1-------------------------------------- ---------------------------------------------------1-----------------------------------------------------1-------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------------1---------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------2------------------------------1-----------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111------------11-----------------------------------------------2-- -----------------------2-2-----------------------------------------------------------------------------------1u*******mim**s**l*y***4***dysu*up**Wv*z***b***Pn*IJg8ORJQ*RQb7DU7--------------------1--- * b.1.1.3 C2 set domains
[ 202] --11--1----------------------------1--------1-----526----1---------- 2-1---1---------1----1---------1-2221211--------1----------------2---1-1-----------111121113121111111112111-11------111222211111--1--1111121---1-232111-11111111113-1111-111121--1111121----1-221111111222121122112211111212112111111242111111112111111111111112222111211--11111---11111111111112112211212211111111111111111111111111222222232423222223329211211112112441223122211112131212111111121-211111-211111111111-1111121111121331111121112311121-111111122222222133121133321211111111111111111111222111111311111111111211111112222211111111212211111111111112111321111111111121211-21-31111112211221-1221121111-2111-1------1--1121-111111111122111213112112212111111111111111222111111111111111111111111-1111111111111111112111111111111111111111111111111111-111111111111111111111111121111111111221111111111111111111111111111111111112222222221122122222222111121211111111111112222221222122111111111-11212--111121121---31111111-11-11 B978HED-YAC1IEHBDEEBBECDBDCDDCCCDECFBHFHBEEDCECDCDDDFDC9EBDDFDBBDBAD49ABDABEE3GD999A9BBBBGRHDJHNFFED7JFHGI2LQDugl*oodSUSRXXR**OjN**x6*b*PQTRcNWfQQWRRRgRR*SdbURVwoQPPmN*RWWBOSNFJNH*GKIILiWkiBmPIELPOMD * a.118.1.14 MIF4G domain-like
[ 203] ---2--113112121--2-1-1--A338B731----21-----1111-1-43212----1---1---3 24Y13111------34266-53--935555564555-778-144-H9-----3-41----22211143322-111---1--19-1---KJWG1M44---7D33BC2N-J----------1111-----1--1----2222---1-1434--123--------11-7214--1-----3----2--11--4-135454565555454453-444455512231322222232H11111111111111122111332223323243322323222221111211111111---1-111-1-11111111111112331112332-2-42222222232451333564262--123-3431-----1-11-----21*4332-----74A351--324-212221222224--322-21-197-5225245D77C91416-332212362711111111211-----------------11221111-1111-----155413A9455898884777755C788884595744451-66212322712135155224423232332211-422432--142124111231222113-11318E11412142121126622121122111444465212G3I22343434473554337975E--14--1------7625694ADECACCD88-C899CBC9D9DABAAAAAA65735556AHA99BBABAACBC8A686A77881-366566666666--2122222233312137222644455154226112111211148A9BA6AB83988918552---------8CC544443497DD542333422211111-16784455--------2-1----------------------11--1-1-2223133C4 1-1123d-31229534674CBBAIEID4355655558665566545736EJLRPB9763444423332-2416-221-11423231211-1361133332-34131-2*2*WeRWWSIGAEFKMTMEXJ**Z7QRkGKLGSGISODIEF7REEaIRNONIOcE*eAFUJFpHKc21L8-732-31D88B67483ROHT* * c.76.1.2 Arylsulfatase
[ 204] --514-33111111122222221154464552-24--11121-1143214455-325344332111-1 68A1A12433552353455-562244554562A666658537686582466455953411D944B8AABC8344433345463122228A6A1621---2942272534111111112211113664669555474446511154D67875545776654657657DBC7254511264453434113445347786787C2A779B83655349A742282766776755B3444444444444434446483739932433983367555521665766777745633333333333433334343333338845498881327B454476453547541343C164448635231221332254421-644276631111174D9C6324458577777777679-AA7A9B9A4B6-A77A995CE998346358A678775563333333337624477-111111211-----1---------111112323457767BABBBBA6788AA9A768A79B9C879A1256A685755B6698535576584343444543434453415344435444158459667944548955522223323331-11111112133345A9B7656488878888966978866567681-25646------77675957887777988-7778888878877777778666775559868796787677787666677776166665666655511-5344342323468873335361222334466577655333A5AA9A9A9B7A99A69C94333333335123944444788999898A8899822323255441122221222222341-1-------11----2---12111-5331112214863 12--422-9125234477766889A486657989875A8879A555564699985737576734455523A83347947653233245467874865574563465-3O3C3346623451123921437P413341112432411212-33251536364534335A43423816BDA*EDDFBIKLWBMKD99859B * c.108.1.6 beta-Phosphoglucomutase-like
[ 205] --1131-13653JF6811-----65--122-2-11--1------11-121K54-21-1112------2 78X2K57255391966A34-3511BD233333BB3B84D7128D742523W4751662--CC72G4MPF651---26---768--1D4CDFI-G342--2D29BV4U6J--------------43622425212631115--3M-D69I86pH222-1-----M2C157E--1---------5125222-275ABAAA8CD5BHBDAD1F4464C998538834311411NB3431322122654431211-5-11521C11-1-43315-3111AWK54351---23762755617681-1--11123111256352756-3D93B6656766AC67AAA132277434B-732CGH7954M256C393-37-HT8731-1--55T7EIL33-37B1111--121-I-DAS88T8C383-9A9AF4J696GQ8858672542935343333333329532664--------1-2T------2---------4-45741254*57564A53332277D775333649D232E-2-1-41DL17914711BG11-431--1----8C1615-33-1--2-312---A-21413-13342BO336---------1---1-111--E14----6347562-432226323321132225227---G313------1-3-18111141183---2-1119--M311511-11-21165A42-21--11---1211-111-4B8A1--1-1------------3-5-----1---A-22----1-1-------1-11116135I289885A6D26AA677641kw-c-qvk2-33223233b31-2AA23433MIM------94132356---------12---1----121---1111--11---162-3-3---2D14 ----15-----3--11---412---2-131212-2-2212123-------3111--14419-1-----------1------11121---2-----9---6-I21s*---1C*NFNTE9888897UJ6N8x*P-UGV6997C88A859877A75J8H66K67EA88QPKB2ZIBC4--2---31--3--521---39AL- * a.4.1.5 Paired domain
[ 206] ---1-1---------11-1-----1--2---11-111-111-2-------11111112222-1----- 11----1--------------1---1------2111-111-212--------------11-----1-1-----------111-1-2----------1---1-----------------------1--1-1-1111-----11--211--11-----------11-----1---------------1112--------------------1------1---------------------------------------------------------------------------------------------------------1-----------2-11-------1-------12----1-1-1---111---1----------111-2---1-1-1---------------------------1-----1-------------------------1---1-------1-----1---------------------------------1---------1------1----11------1-----------------1-------3-1121-22-1-2111211111-1--------1--1-2-1---111111---------1-112--11--------1111-1-111111-11111-----1-2-------1-111--------------------------------------1----------------2------------------------------11111-2------1--1111-11-------1---1------------------1----------------------------11---------1-11-----------------------------------------1---------111 5212RNK-VFP2AAA88369AAA6667889988885734566678877AAA89B8996A9887887883999778484867BB9997695768A8C64664A7FEF-gKAy*****tnceiksh**f*i***H*z*Vdbl*at*gWqcbX*dS*ksjoqKTNXbZTCrRSdLeaU2343D22432JLOT6SA96****K * g.50.1.1 FYVE, a phosphatidylinositol-3-phosphate binding domain
[ 207] 22412145444455452142332461135234-131112-11-231-21-1--122225232222-11 48E5B-2322311168889-8911DJ88888BCBCB88RR465934222322646521--63H279IBBA2111111112255222331121-311---24224917442222222222111124446544667466656323678755555134433222246235463-2111-12-11145522231324445456453555555433314553244311111111132222222222222222211222---------------------------------------------------------------------198155555455647365411115133352167B969AA454722131--8226565222228EPQX6379C9EB33443444427-FGLEFMGMCE42EBBB87IB86GMDE453BC8BACBCDH77777777E783694322322222222222222222222222222549B419BB7AMMNONMBBBB9QRMOCCCC5DMJXKMLE37GFCCC787G8I8OH7BA43556733333334359FA77B48232474554-4754B65785535AA6G2342233332332222222244344886346229351548888577555666556482-136431213336767653AAA7A887A9-AA9A977A9AA89AA9AA7999657655455555555555555B8778878317888888888883223222222323917782224342222222239887969275B2DEFFBEGEDFGDD5B99222222222433393333344245445767844422221124111122--------21--------------------------23554222223721 11--223-522-33253543344444444454443443333333443344447545444444222111122123211--112222211122332222332312344-5F3F5A665B44243648G2A4AI6-56734258548334245C33B365534AS4A95AACEAE7654673*3449499GD4EB5763433 * d.15.4.2 2Fe-2S ferredoxin domains from multidomain proteins
[ 208] 34221444433333344222223211-1321111---1111112112--3783-35323522222-22 112231212114351-111-1111211111124212115611-11-1421213111-1----2224-112123334332113-332-24432-333---1211-44214---------1----2-2121-1211-322441122-367266543333223342131263412211111112212333221756666555654546544226627554544-245354243333555555555555554655632222226121334412413652333333313433311111111111333333443333322211122231113311111111221244-331214324121-86-1--312222313352-2644511----12-22-21122122222222223--3--4332-31-333122-221311421112213113-2---------331-122111-1---12-11----1111-11--11--322312332344445553321667633331466422442365343454454343343555321-11----112-36223324233333331111-2-11136532422111-1-----11211111112111244343333332523354634434553334542--211151-111133651314555455444-446444444444444444534355-1455553253335545571544555511222222222222--1411111222223323----1--1121---16666635332645565334663334755511111111132-15111112243458556554445544345-331111--------213-------11--1----11--1---12322222222--23 76DC87J1R8A57887AC8A8898C789A8A797845878678857967989ACAB785A9A7745661676587969686784558A6A95A8658977777CBL4EgEnenakbSJBNPLVJZgIbK**R6WUpOLDJXKURJJTJEIUJAWHXLQNNSQNVJOLgTPVOVVF9DFL*MKKJDYXdh6eS9LCC9CM * c.47.1.2 PDI-like
[ 209] ------------------------------1---1----------------11--1--1--------- 7DI-2--1------21111-11111411111131111396--1---------312-------3--114451-111-----21-538549A8818334--36344H5A4511111111111111122252243333-1111---1----1-----------------11----------------------634666664784676457DB779676759C4712222122I1---------------1---12---11----111----2-----11111111111-------------1111111111111111---11118HG78DBBDDCD7C81I664434261-16133-ZW6ED92E94858Q-2-7AE44451-1--89EFF766AD89C44444443335-B9A9A8B54D4-933465756687DG64364A9799334111111119554279C----------11--11------------21356766A97CMMOJPMIEEEDMLHNGHHGAFOLLKOMK23FIHKHBABHHBDF9BAE8D88762233324554EMICXgIIHaREPHRTd5UUSSSMZFHQXQYc*FS1211-11111222222222224312ECDAABDBLBCC7DDCCEDIGFEEHEDFHGKH--28CDH1-1111B7C7976BAABC9BBBN-ADBCDCBBABAACCCACCCBEC97885BB9A8ABAAAAABABAC988GEF83-7778888678A9--1411111555597MBJ3333222222222323333336243LAHIKJIMKMFLQLKEIII---------88CCFCCCCCJHEFE67BD8DF668433321B16644441111-11132-----------5------1-------132311211155-3 -1------------------------------------------------2----------------------------------1-------------1----2---121--------------------------------1--------------3---2--1245-7--3---11111111545H-A2--1-1-- * a.4.1.12 FIS-like
[ 210] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------11-----------1------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------- 1133DJF-gLD1O9Z12PJFCKKA2ECGI8AAFABC9IELCHGOBVi*12HE2FEBE*5G35E8C7992F89A76AD798888E92E8DT*i2OGdHDI*D*EXp*2GR2XVePP*QIJGFLVVsXIcD**X6XVfKILHYHM*OKMKGIVCLjMTKv*FQP*****G9NSDQKD22MEpA7FD8****S*R35d***6 * g.40.1.1 Retrovirus zinc finger-like domains
[ 211] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------1--------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------1--------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1----------1--------------------------------------------------------------1 543346D-723399C9899A7A658378878876766656475687887CB99C77AABAAA83678644A8455695887545449A9NcM8RVKABA78IAQOQ2DULn*****thYs*e*i**b*d***4***Xmm**dl*uRngbPvVR*momlsQXN*WVgSpOZVLTYK-9CI*DD97CDJMZCQAcWECDAF * a.21.1.1 HMG-box
[ 212] --------------1-----------------------11111------------------------- 3342244444453533345-63223344444333334544233322433222333333112223423333223333333222232444555525-42113556377848-3333333-323335222222222223333522242446455634445555545444444325222225222244433441755-7777777677777744555677755575555555557865555555555555555555-5656655555665566666554666666666665566666666666666666666666666766666665565755555557576555667756655456324426223243444515642566663333345444444444443333333333417765655534434443444444444488465444445564444444444444664222222223311333333333333321222454534444676676766666666666666666666665656586A8AAA88869977766A96787777454698B354859444544436454556458888C935544444444444444444446444555AA8899D6BC9CFFFFGHHCCCEF-HGEGH215344533333387777998888888888-8888888888888888888999777798888888888888888A88878885197778777788822473333344445786988878878888776888878887878A888888888188888883333333339CBBBAAAAAAACAABBAAAAA9A9444433566644443334333374522223-433332233332223422244344333333754 A922784-TAB4333111111111111111112112111111111111212311111111112233431244333553243333231112421232111112242512jB8353549343264276254DV4-55344436345324443444443445-13594524224123369ALfHFGA7978D1B9LQD8AAD * d.265.1.3 Pseudouridine synthase RsuA/RluD
[ 213] -------------------------------------------------------------------- 211-1-------------------1-----------1-11---111111---111--1-----------11-----------1---1-------------------1------------------------------------21---------------------------------------------2-----------------------------------------1---------------------------------------------------------------------------------------------------------------------1----------------------------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------1--------------------------4-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------- 5546*k--J762324-1513111221234211121--------22124311212111232221-11111211-32------111--11-33-1524-----41121133C*******kokenwm**g*x***6***Vlih*kk*yQpjpiyYb*gdX**BBGXPg86KAIH8O*61--11-1-13HEGF3B7-134455 * g.43.1.1 B-box zinc-binding domain
[ 214] 45-231122111122-242224-3422432312-2-1211--111-23-6A781---1--1523---2 9DC-s55555627436655-58226E545556B6657EKH88DBKUN5IDCGKHJ42M22DEMESIMeiPC9AAAKGG423-84-12242453A-31--2--2262C39---------------35224426444577CC---C7735222212543533233243886413111-131-1-DB434B92524555554772535453BA669656595A4852FHHHHC7H-444244-44444444-1455AC33456629LI-27-62A6444453336888422B998CCBA8AB6666566566666467764444642-6C3333353859487726869374-926-2343334A327DD74342444C885-----327333223123266666666667-33433722AI7-TLLONMIWVYIM633-33B58498375--------32274362------------------------------43C12154434354544----5547------54D-431-----535443544C71-2323332--------1-1-3351--521153222122414233322526735-----1-1-------------111322AAB514--4265666613233314245138--24124------FADC9A4FEEJFGGGDD-EFEFJGJDJDEGGEEFEEDCAC87448CECCCDCCCCDCCCCCEA7DDDDB8-CCCDACC5CCAC--1----------31223777464244446679----------52--1--212-121--2--7559797752688A999996679A2544244444------45------22222222--3----6-----2--222-82--1---2AB73CDBDD1521 ----356-61-3--2426161446B555576565654626566534225365A342341322212225112-12321-1111111132223324436155-31231-2A4D4125723-41212863449S4-4491123544332323132222--22--433-121-18125152-4P536134-1634264AB9B3 * c.55.1.10 ROK
[ 215] 44-222464434464517566436585576424332222222221222---1-3212111-3323-23 2443D2222374219HHAA-AD22BEBBBBBBHBCCDCJK465826423333877415--87F3766C9533333444-EsP424534334234331--2753275554222-22222211112776459559752442122-93434733345332321124464A685132143332114521344426646666687756658665477546666556445455541684332222322223226235415-5222132265-----3-32-3221--1-11122-----------1111111111111-21---11116D546---112121221993322242--52249TT7681349111-311135366663423366C7A4546648422222223224-65356B59584244464434443459534255434733855555555444266563243322333212313122231333323235FE515654478899734444BB6B444423B68594B55997735554673966658451653333443553456589557575A977927469725228558995F399325555332322222225B8672275846575887C9CC86HGBDBDDFKBHGB2-33465------76BA598777A7A9A99-79799997977859979989A9A96767976677776657567858744455387777777777743563333354445571B5553332223-5662DCC9D6C334A6AA7AB9A64A8AC4677334444443456665555587977454444433387774342454445-------------------11-------2------11---1222123233 4211236-C8513417A54643487747466767555767676866935358FA755532224562132513114241451665662436F7A59C5357746525-2949544253444-23-553335d3-56522235422-3143232122734248127395943J46421665*66645AAF97A47883442 * c.3.1.4 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
[ 216] 111-2-1222232221-111111----21211------------1-----1----------1111--1 13513--1111-1-22222-21--2622222133332-22-1--31---11-112--5--2121232342-1----------2--2--1-1--1------2122E-221-------------------1------21122---1314512241112111-1125136492-12--1----1-21111---1-312122---111----122222--1111-4--------32-11111111111111-3211-1-------------1-1--1-------------------1----------------------------1-2--2-----2-----1------2-1--1----21---1-11------2-4-43332-----1185611543532----------1-33733335233-5224232332114112132221223333333333323344334----------------------------1-1132147646655557333334455333323554444412324425236231454621---1--21111112-11-11-----11-2--1-11---1-1-221134--1------111-1-1111111-----11111412523122222211152221311324---14-1------12331221111113112-111111111211111111222223112121111211111111131-121131-3-2-122-2111---2-----111121222---11----1-----111111211112333422442232322231211122122223123233152--22434331221111--31221111-------13-----------------------1-1--21---2----2-1 ----1-U-2--236533433322535522322265422223223227544355333434334253134-31133312113233222224343344654442444241464*******bjjWYPY**btw***8*Z*qclYugenUedgZamiS*lybn*Xov***gY*bc*bd*L2112H11133242B2942568142 * d.153.1.6 Gamma-glutamyltranspeptidase-like
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b6o*H6HEE7888E98L768B87*56D9A6A7ALa6CND5749B6662C7A2U353CJXch*Pxe65777B9 * a.102.1.2 Cellulases catalytic domain
[ 218] --211-1-1111111-1------111122411111111111111422233332155435641223133 1412C415889223B9978-7B--BH777779DEDEIKYS56393435233-B67544--B752B989AD31333111223212222123333333---432354253111111111111111244445344534111-1222-13214221111111111111122221111111111111--3--222-13222222222222222322222222122342311111111211111111111111211122------1---------11---1111111----21122222222221-------------211111111-232495556556858233346652523112233225433223455412212264221111114496C1-28559522222221223166746B5B341295523265658997111359422335944444444533233221111111111--11221122111111111-118315C87BA67B7B8666699BG666629G9IDHGF2397886264C7A5DF2A554365244444442229D523334436435444143422353433537933-----------------------1-6688747575A66777763777776656767A1-1341611111166564567665756577-6778755767657667667AAA765667677677677677776866655564167777777777711232212145553668B111212111111111ACBBC78356A2DDDECDBABEGDD9787311111111159886666678899566666633322222142332222--------211------------------1------42322222222--2 21--444-JAD244CGGHCFMNGLPJIAA96668A889887A89ABCCDONMQRHPGCDDDFEA87874866788CE7AE5GGE7K375AE7G8C6A677557A78-2VA97A437B8665997EA595Jd7-96B5554A888356744882B7965635545571635944649768w7877BFGXRGIDE9KFFFF * b.43.4.2 Ferredoxin reductase FAD-binding domain-like
[ 219] ---1---------------1---1---1-11------------12----------------------- 6-9-231133322194255-58--5A53656278684577-3-3251-154--342-4----1-31877614222333--13--------1--1--7-----24724--------------------11--1---111-------211-223--11----11-4----22--------1--111311---2-22222241423132411-3321233112----22245325-333333332333322111--3-3223-32311--22--11-----55515541--22222221222-------------411---11111--2-11111111111---------11--11--22--------------1--37225-----15412--22-1122212221111--33133221-1--2-----1332--12223-1------1---------------1-----------111121122111111---1-1441-1---11-12-11----11141-111-21-1-2--1-15-11---2-1411131------------11223122-23-11-11--1-1-------1----36---3--2-2-----2----------------51123-413-111213-2121-1-211----11--------2211231-----1-2-------2------1-------33311F8224212222222221112---1-1-1-111111111111---------111111412---1-----------2212211--113113152434-112-2-1----------322332332321223287975232--------11-------------------------------------1-2----------111- 2211MHG-OCA7HJJQNiXVOWJktlZBCABBDIKI9DCECHFBCDePQdXYrsTUWVFJIKO69975345485556454577766333QrYNage846CFIGPNP37*N*MTUQLKDHAMKJBSOELHl*I6PIcBBBBH9DI9DABB9CECYBFCEHFPKHmSV*mn**m*TS6LM9gAAAberge*SmiKQKEPRE * c.69.1.17 Fungal lipases
[ 220] --1----46676545112--1---112-1-21------1-----------1--11-1----121---- 8AH8q323223334A9A66-6C3389666656E999GBDC885CFB2346625652232288M3E8ERSRB211133222B5944454CCFA1B331111A546W7L6I2222222222222211-211111151DCCEB225DAaBJBAAA89BA886B98AC8FFFCD67786768686734111324DADAAAAAAAEBABAABAEELKFFAAECBDCC54444444PD332222222233322411132112122211111331121111111122211221111111111111111111111111111111111111BIBDBA9ABAA9DEBBBFDA888CDH21HD8CBDCGDB8ABAAB9FA524G3G745833333243446735747633333333336145436746335265557558A575373A4556746845422222222423223772222222222222233222222222222324454347544EDDFFEBCBEBGGA8BCCE9CGDCAC9822BAB58677B688847967689643333333F48496423254434443342558957A57BCCCEQ4522222121122222131212222237775779A86A837777689767875688797212856622222274455775765555566-6655645556656455446756555667779567678577796953443556376567756567522464444466663276A444443533334444333334423297DECDFFIF9FKAC57A9222222222497795555586855DD57476765333322554444332222222253221512-11211111111211-111122642323334I22 11-----2--1-1-111-----------------------1------1----1----1----1-1---------------------1--1--1---2-----------6------------------------------------------1---1--2--4-21----11----4133G1225477BH2A4786---6 * a.4.13.2 Sigma4 domain
[ 221] ----------------------------------------221-------12---------------- --2-2---------------------------------------1----1---1----------1-1121----------13------222--2333---A-1-194----------------212221111121--------2-5-2223--1------------1143-----------------------21212632-3224321---1-224---2---ENOLJ7----------------------2-1-------132----1---1-11-1111111--------------2222222222221-11---1111-2-7-675877717-1-33-121251-3--1--12--1226-------21--6------------------------------------1--11-------------------------------1-------------1-1----------------------------------------1----1-----11-1--------1--------41-----1-------------11----------1-1-------------1-112-1------37-2-1---------------------1--------13--1-1------2------41-12---------------------11-1------1-1-1---1-1-11--11----------------------------11111---111-2111111---------1-----3-------------1-------------1111-13111-33231-------------1--1-----1--11------1---------1---35B8--------6--1-1----1------------------------------1 3211E*g-*bt689F435786656557554555866664555546656775575475455763562242643G6K343263ADBCb3446H736M95434E55A773dR**fdhkdiRPKIZYPtrNwP**f7*a*KGUOVPWiSLRTQPbKLjPlWSgIQKNnVSNkvdySdXU2KSA*453ZIb***8*q47LVTaJ * c.10.2.1 Internalin LRR domain
[ 222] --------------------1----------------------------------------------- --------------------------------------1---------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1------------------1111----1-11-----------------------------------------------------------------------------1---------------------------------------------------------1--------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122B9O-9447GFHDFEEEFHEEEEDFFFEEFGHFDEEFBFFEEECFGGFGHGDEGFEGGGDDEEDE8CECDCEDD9EDDFDFCFCEEDJDFFEHC9CCCIFQUS1hXI***w***hfebhrh**Y*c***7*y*SmfX*Xk*gZlfbSvfS*hxmhnSdaMYSIGOLMTELeN2554F7684496DCE967A****J * d.189.1.1 PX domain
[ 223] -------1--------------------------1----------1----D86--------------- 553172222223225BBAA-AA55D8AAAAABBDED9A9A255844523443455435227693977898322222221111123233444414342--56666324143333333333333363323433335344444---6166666663433333222444498742222222222222212222213133333222222222211113222211112331112112121111111111111-11111231222213331111321111211111111111111111111111111111111111111122111222122123222222222212222222332112421211211111113221-32614244211211322222123322322222322223-334344442631322244344433225245543333556333333332222334211111111112222222222222221111133251222245444453233333563333344555565225553553334666333732333222322222324664C78422312322215554443449998FC27534122222-212111111142122456656955684488888576888888678672-34232------65444534555443444-4444444444545344445565534454433333333333332644444442234444443444411275455555544995922225222222233354665574556699998A89B777758774333333333566877777678AA676767745522221121AA66553332322222311111-111111111111111111112131222222234 64339AA-N754687588766667655777767755776756776866575576666466456965465656566675886666874345A988778667686IHJ3DOBSLQJLMOEBB7DICaOAYD**P2JNa8CB7LEEJH7FDE8HB7RHJIMJIF8DIDBANHDQCIGB98C6j76599MFJQ8ML8BHCDB7 * c.112.1.1 Glycerol-3-phosphate (1)-acyltransferase
[ 224] ----------------------1----1---------------------------------------- HCP1211-111-----------------------------1-222---21----------3--------------1--111-186788JHEB-J55---5J7BCMBG3B--------------27458757987655557---11BAAA8753255232325574HBEM51411-1-3-1---21112222112222213222321131211122321-1-311333222F41111-1-1--111---111-2---11-------1121----11-1-111211121111111111111222222222222221122211115C51B11121211131255211-111--3-682ABC47353372333133E2FI77E233339GUKWG8JMMGHF69896A7788C-OSNIPNPM6CB1HEECEFGDCEFFCP5ED92A5967728AAAAAAAA6BC745E81111--------2212223212222----1576D354618DGHFHDA6565EECH8AA968C9F8GGM-3EFFAC7CDJGBD94BEJDBB86A23224229AF6BE18D337972AE665-7C8D9CA6DCA9AE95C232222222231211111116347779DB9GFDNEDC5JFHHFGEQPGFGKGQSLPK--2CA5B------79893C49BB99B9C9A-9CAAA9999C9A9999997LJI78A877554656667556546C864668A2-A9999998899A--28444357A9BFBE6732112211-11---1788B7583459CIKLKCJGEBFFEB7FCG11221111199CFG78888GHDHFGHB7D8789B534311819943441111111131----------------------------11-111115B34 ----111-1--------------1-1------------1------1--1-1---1----1-1--------1---1-----1----------1--1----------1-11-11215-221231-2411917L3-3311111412---111-11-1113-1---13-1--132--4--1--------2--A---1-61--- * d.3.1.8 Microbial transglutaminase
[ 225] -----------------------------------1---------------1-11-11----1----- KCP---------------------2------1--------------------1-1----------------1---1--1----8578ATSRJ-R88---7M8DDXBR9H--------------58899A8AC9AA2--33-----72375411111111232112547A7131121141121-4144227-2-------1-----21--------11-----12122111421332221-2222312-12-1--------2--1---1---1-------1--121-----------------------1--------------12-7-----5---143334---1332-1--2156222122-2---1-42K6FI7782222296A8D84A7677311111111112-333253341261422543474323396872141121221EEEEEEEE5LKE6B6611112111221112221321111111111268IA9BBA4ESSUVVOJGHJIPOPSMNNLBLSLRGQLW35HIMACBGHTFD8H4FLIAMEICD1122222A7B7AF88I577E444955719F7CBCECFCC9EE76DA6433323323444445444A649BEH6579569686636565366A7784688996--28827------555A3754786566865-7666655567776554556867BE5446765666665556556613866451-634444444444--2922222CFFGG7728222212112113132AAABA9922398JKLLJLKGAJIIIB9EG333333333A5669686678BD88GEDADBA677111131B3CC88881222111121---1-1-----2---11---------1-32-22222AF44 --11245-82541222-3521442-12111323-1231---1311144-1132523131-2-11-122-------11--11---2--2--3--937-128131-AA11-1R8AA5F744556CALM4E6Fm52E9H2561F69C525542F24I6974B59A5B535B57616H5152143-3-1231G24311B5341 * f.5.1.1 Outer membrane efflux proteins (OEP)
[ 226] --1-----11111-1--1111112111111212111111212121112112221111111-211-111 7DE11111222-3-12322-212231322321111112111111----111-121-----213-22222221-------122153874899617331--38364C7A361111111111111112437224443422211---3131131121111211111132211131111111211112111112-43588888788687778889886788A38A3521334444J21111111111111111111251-2-121-1-3311---121-----222-----22------------------------111111111-2IG6LFEEGFEG8F83O885223261--8214-TO6EC93E82A8B311199B22231---17598745469469222222222121A7978783486-A333558665858B2225599899535111111119332286A----------11--11-------------23576444427FIJFJFE6777EEDG8A8859FHFCGFD12DFACC967CE69A376A5B7655-------442DID7OdEHITL9MFKLT2PTMNQLcEFJRJRSkEQ2111-11111111111111133111BAA88998H8889AA99A9CCBA9EB9ABEGD--179BE------B767974BAAAB799A9-AAAAB99B99A899A9999BA977763A99989ABBAB8B89A986798883-666777766798---2-----111164KBI222213-1-1211114436417232G8EFHFFIGGCHHHG9EEF1--------5879A999A9CCDDC55975765551111-1922233331111-11142-------------------1------23123131116615 1111121-621---2221112222211---1111--1222122-1-11422212111--121212222111321153333111211222-212211111-2122431254c574448344335373356AV4-36F3534433343342364373435779B29632332E35B51321K12152748A1623274581 * c.1.26.1 Homocysteine S-methyltransferase
[ 227] ---2--2222222222-2222322222222222222222223222222322222-2-222-2----22 2222222222222222222-22222222222222222222242222222222222222--222222222212222222--22222222222222------222222222---------------222222222222222222222-22222222222222222222223222222222222222222222222222222222222222222222222222222222222222-22222222222222222-2----22-2---22--22----2-222-------222------------------------2----2----22-2222222-2-2222222---2-2--2222222222222222222--22222222-----222222222222222222222222122222222222-2222222222222222232222222222222222222222222-----------------------------22222222222222222333332223333323222222222222222222232222222222222222222222222-2222422232222-2222222222222222222222222222-2-------22222222222222222222222222222222222222--222222222222222222222222222-2222222222222222222222222222222222222222222222222222-22222222222222-2-----222222222222222-2222---2222222222222222222222222222222--------222222222222222222232222222222222222222--------------------------------------2--2-2222222 ----213-----78723B65333453655333334332324454356534345244664223336332323342153343222333234598358543432949G9-22-*TUQO*JbWaYRPS*rb*Y***8*o*YiXUXajwdIVMOQvXL*OQn*t9D7OcSAcbV**8FM33222N33222537A582214E332 * d.14.1.9 Imidazole glycerol phosphate dehydratase
[ 228] -------1------1--------363362122-----------22--1-22-1------111----11 2542P-2211221-KJD98-9M--KTB99A9ELQSSGPbT3I8G9A2-34425B85341159C1C3QGJH711111221--6A2---1--11-1--1--46544J7852--------------124354235342GII9C111A5CEDG9997CAA544754898DFCGD54555454564546422----14898997896568986422-37649-1172-2122121941332132222333224332311-1231111---2222---2-1-1-331----32-------------------------4--232-----11621-11-111--2322-121--13-41--196-1-11-1---21-2-6158AA2-----88LFB2-2848A8111111---17-95E95D7F3AB-75517659E9759D576787747764B4444444452214573--11-221---11111112212222----157M515CA54DKKOIF75357BBEEA8995BOGJHAAC22B974893256C4H5331-12324-------21129846252-11121111-26411222156749B--3-1-111112--11111-1111112--561575246364544436534345264454--15562------11121412222222222-2222222222222222221322324623231312323323212611222221-122222222222-11211121152414B7411-412211112--1454654915494CC9D5A9F889891989----------4436222224454433354574431111-1-1787786--------2-1------2-31133----43242111312112622211-3 2111695-JA64544A6E79867GEEF448676364742524256598AI6GGG558A6153223232141372822283256626122B9468J21136455876-8hCLF8A96865756767C2B6MjA1E7G57528969465243A33B553AAB987FBAA547GED7K3FGEyA98GFYUVl4XPD79ADG9 * c.69.1.10 Carbon-carbon bond hydrolase
[ 229] ------------------------11111111111---222212211111111--------1----22 2282422222222223323-22222322222223333333122212111112222112--3221324243211111112121---1--2222-511---2333312223--------------111111211232222221112-5223332333343333333242235333433333433333-----111111111111111111211111112-11221122222233111111111111111111112111111111111111111122122222222222232222222222212222222222222222222222-211211111112122111122221111221311111-1---------225-4655522222222222222222222222222222-22222222222-2222222222222233322222222221111111111111231--------11-------------------2336321111122222222222222222222222222222222222222222222222232222222222222222212211132212222222212222233234312211111111111111111112211211222323525424444433444443444434--211-1------22222222222222122-2222222222222222222222222222222222222222222222222222-222222222222---2-----22221221211111211111111222222121112322222222222222222---------233332222233322222222222211112112223333---1-111112------------------------------------321 BC77CDG-iHP3EEGBCCBABBBBCCAABAA9A9A89BAABAAAA9BAAAAAAA9AAAACABA9B768566896999789866767A99EMDCEECDDDCBE9EEH2B*JkPOLKQPFENGHHFVaH*H**f1UTvOGEGMDHOHDIEHKLIHQELHGKKSTHEIHJMDIVJMIE6TST*NOOKJeNcsCXOSUOKLKj * b.62.1.1 Cyclophilin (peptidylprolyl isomerase)
[ 230] --------------------------------1----------------------------1------ -------------------------------------------------------------------1--------------------------------1-2-----1-------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------1-1111----------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------1---------------------------------------------------------------------------------------------------- 1--188D-2---85823322332222233232322242-24332325323545444322443121112112311111-12211121545655375343432438CD1d-1i*******pthv*u**t*w***F***kpts*j**ta*wok*ge*z***tLu*cVQhK*WZpZ*aM--2--2----11262522-53561 * g.49.1.1 Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)
[ 231] 22663267777777785645674666654756787A99BAAB97767866777B66677475554-44 5783675444444455544-45446844444476664565486774554655445534334544465545422222223445565554445535552--4544564454---------------555555455564554466648A675555556665755576445656555555655565333445424354444443334343344444543433333433333333452333333333333333333343-33334-3-3333333334333332222222222222222222222222222222222234222333365545666466645463334444645334455744A55353774465734565444533333586574455654533333333334-54546556334343343334343476555444454434466666666555454455554444444-1-------------333344545555445655555555545578555545578558745464674355757655586644454444444556666576576576666665676667656667555567556566665716111111176656656755546454666666566776666666754-246451--11166556746666666666-66676666676664666666675466676777677787777786666666644755555555555--544444455555565466767635545645644444444446465565554555565645433333333755464444445444665444444444444464554444--------4---------------------------31333333365653 1121555-613-56443435444455333333344344343663436434434463356334333333134334333-43443333343483363833433333771552L66575A665678587994Gl6259H362585661456467337586965AA6B546E68C67665455Z6437464784685995644 * d.139.1.1 PurM C-terminal domain-like
[ 232] 44414133333333245244333343333434222211222135233434755122233232233123 2323213334343422233-33223533333332222453376721331111222322112222423221111111112133221-11---222111221222221-313444444565666662221222222244444222244444444443334434344356464444344444334121222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211111111111222222222222222222222222223222222222222222222222222222232A33322234222221221511141222244A68364444442222222222214466462258125222758872A944322222624621111111111433112211111111111--112211111211211112422523111254666542222442344444544923322266224222242424221222454222222222236211111222224222221212222244454463222222222121122222222-21122222121222261222222211112122222222212221211122222222223232422-2222222222222222222121222221111111111111111222222222222222222222222222222222216222211122222222222222224222213222222111122222111122222222221124444423254222212222233231222112222222222221322222-------21-----21-----22122222221322 BCAAJJAEcFIADBB99ADA99AA97BCBAAAABBBCAAABB9AAACEABBBDAAABCA9AAABBACB7CB7C8BCC7CCBBBCBB9AA8EA9AABBBB9BDBCGG79IHIEODCGBEDEAGFCKUCj7l*Q2LKWC99CTAFMCCFEEGGDCMDEDBBFNNADADCSBCQ9DGBFEFA*ECBDDbQefATLCCCACAC * a.129.1.1 GroEL chaperone, ATPase domain
[ 233] 33333343334333333333333242233343232222222222222222333333333432223244 21222---------22222-24332222222222332232244322--2---423--2--23222233232------------11111--2-----2--1----13211--------11-----11111111121---------21-111113111------1113111----------------11---111111111211111221111111112111111111111121111111111111111111121111311-21111--11111--------------------------------------------------1-------1-1--1-1---------1-----1111111211111111---31-211112122212221122222211111111112-22222323132111111111211122233232222223111111111112-12211111111111--11111111111111111122221111122222221111122421111121223533-154333222232232132211123-------121321-11121111212111---1---2-221231211111211111111111111111111221111121111121222111111111121111-1322211111111211111111111111-11111111111111111112222211111111111111111112111111111211111111111--12111111111222121111111111111112222221--1134334111223343112211111111111111111112112122111111111111--11111111111111112--1------------------------11111111112--- FFFEGHGCoMFGFEEFHEFGGHEFHEIEEHHEEGEFEFGFEFGEEFFGFEGIHGEGEEEEDCHEFEEGAEEEEFEHGDGFEEEEGDFEFGPEHHIKEEEEEKFEFREFSEYRxWQUMHGLLMLKRcJbI**U-aQbKLKHYDMMMHLJJJNKHRGGGHJLJDGOGJJXGIWHHGFFKGE*FJJFHhOjZEQTPTKHHGN * d.153.1.4 Proteasome subunits
[ 234] 2267327777778777455666666665475687798A999997877766778A66677475554-44 5674655455544455544-45446844444476664565486865554554444544334545566544433333334555565554445435551--4544564544---------------5555554555645544666488657655666665655576455556555555655555333446425456666654545564555655455545553533344444563333333333333333333343-33333-3-3333343343333333333333333333333333333333333333333333333333367756888678765665555666756455458866676355797785733664444533333586574455654633333333334-54546556434343343335343486555445555534555555555555444454454444444---------------333344446455446555755555545568555545577558745454674355857665576644454444444555666566576576666665676666666666656566556666665616111112176656556645545454666666566666666666654-346451--11166556646666666666-66666666666664666666675466666666666666666666666666644655555555555--444444455555565466666635545544544444444446455555564555556545433333333644474444444444554444444444444465444444--------4---------------------------31333333335654 11--543-511-33333333433333343333334434444443443334435434344333344433133334343-3333333443346435534443354343154396546586466565965A4Dg6258J352384462666535448464665886A545C78C64554346Y5443452664474475745 * d.79.4.1 PurM N-terminal domain-like
[ 235] 22111-3333221233222132422----22-5621-1----2-2161-1364-31-21-11322-11 81C6822833422223355-5422565555546767578846775741-443747521--417-539567-13441241341632131978428661--56765B8G56--------------142539357552999FD-1-96C788A8A33677563533538EDCE342232233221221-1-11-34212132133323342315574331132112-42232349122232232222222112134541451211265332424432254733342221332222221111222222212122223122112223521E544444456444255-2314351-121--34434---13-2-331-3147567-----54875A545744544344333324-HEEGECEJ3D51BAA6578876DAB9B5673479776448888888859969764--------------11--1----------1237-43111377768545553338A7877347677A582245335412154272553133553-------524432-574-3663C96672A89654A156355A8341--1-212--11--1-----1--2334242B641-6213211112122312233232--12-11------34532546664644433-65746535356343464464573332362576556856575763335655442411121111122--1111111343351222---1-1---11-11132323-412-9544439A855A89A3AAA333333333-414311-112341166945447563332--32223344---------------------1------5-------2111-11-2-8834 --34-2F-2--23356554255346331112222131312-2233354347657742414442----1-2-11-121-11---11--11-8351-1-1-1114676-4H-lTVROVTJFFKHMFYOFUCz*R2RMWFHFHSDPRJDJGHASFDSDPKNRFKNMdeDBTEKVKOHA422-714-38AA9D6GB5623433 * c.68.1.17 Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain
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c6189B5757746846644665495777658B45444865C68757545m8655585CD78775BA9A3 * b.40.4.1 Anticodon-binding domain
[ 237] ------------------1-11----------------11111-------1-1-------------35 244-21111111115ACGG-GD44V9GIHGHFADGF4479-33523131---111111--342-1221121---------11---1-------1-------1233-3-----------------11-2-2---51CFF64---K-93252211222--121-2321568D-2-----2----11-2211----------------------------------1------21------------------------------------1-----------------------------------------------------12--1111-11----1211------1-----111-124112--11-1-1-134-441-----13dFC12173799------------76M56J9F-D1-E333MOVTPNPV11--1-21----37B1111111111121752--------------------------1----121-211-1211112-2222---42222113-3379---11-314--43424--25222111-------32-344485311-122411--12122-12---1-EM361-------------------11--1-----2132-3--1121111111111211121---1-22--------------------------------------------1---1-------------------------------------------1-11-16555-24-2---------------11121-1-2-1512111-1-2---12--------------1-2------1--21111111---------D1PP89JK--------A12-------------------------11-11------4-- 9867B8N-RB*3BBK212-1111111111-111111111111111111111212-1111112111111-11112131-21111111111111111111111217662AI**sop*dfPQPNQVSqkPoS**XAfS*PTQOcOUYTLRMTJjPH*RQQWXPi*i*seRrTV*pocX-**6K366752-4-1-1IQ9JKMA * d.58.29.1 Adenylyl and guanylyl cyclase catalytic domain
[ 238] 778FDGA799999AD8CBEDEGEF4335274386DEDCCBBABDHDFDJIPQJKBFACCAG476I366 7DI292431111-221277-72--24676663333374342BAB1112511-1131-1--96738264363------146BA258969BA574A231--1334466413---------------B85A9F578CE3447B8675397DCA8844225334424756A98832223334323443333FA2321446464552546445523325553345422422222257411111111111111221122--1-111---11----------31311112-31221111111---111111111111111124442221HB8EAGGGDIED4F4A7FF345565J7575B7DJMHCKBBKFBCDDG7225F44227-1-11866692529B87611111111111-56866A66244-4112664323444755341564664244444444495556C4D-------------------------1-2-132223111136776778444355344434246559696-256554133241342235643363222222223396B3LLJAFJB8MOHGH6JPKNKEVPP87D9BAHV544944334332333444439766866245342522144455624856665479688--1324411----73525534444444444-44444464444444444445753683568556666655564552432444411455455555555--14222223222948242223332334143353342324322926666666D5766695341----1---2267611111273662343333434111111BE332244--------521------------------1------7AI58B9DBB7742 11--211-2--222324431112111111111132221111221111223332313121212---1---1---1------1-----11-1234111----252232-2437242223333223335252HZ7-644321342343233314334144231-215352311534423412H5323444462414631442 * c.1.28.3 MoCo biosynthesis proteins
[ 239] 222114756667777724324224533435731121111111122-2-11342123224434341--- 44679344445322C6777-9A11A977777399A97EOP56467655676287E4543344G577BB85412224331--25121114442-2111222117434232-------1-1----22313321222233312---343444443123322112324244464212221212222533442211535555554536565456633555552415587644444463333333333333335967573718713322CD546756887266664464445543334323333344444444444445663336666414-444444344332533112262-123-11153162235134443144217744533333778455554444455565455556-7777979C5A53655698E878BA3C8666464544666333333335443434422211-1122112222222222212222215467-887697BB7AB77777AA6A88883776F4A892334445366657583365311133322223256444336A45444445333142525635222424314111-------------------21366555895246551132115131122111223--1653511111142326335555555555-55555554555554545555432344344444544443644455333334531455555555555112311111334346575222212111122222433442556523456664554557733325454453443333544444534445334534323222222335533221111111131422323-3-62222334352233---22123313336511 771153C-E56155344743535656354233334213123323543535577A3335454422223214342223323524443233448342345534224747-6C6FAI99F8A968899KG9K7a*F-GBU7895F78D878B78978IACA8B6AK7C86AD67BB9C76E95*46567BCGF5F98B7B65A * d.87.1.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
[ 240] ---1----5555555-2A11111-8119165-1-----1---11--2--2-14-34141-1--21-14 77n2F11277912136433-38--3833333357783CHI8538PSM23D96MMM339117625D4EBI942111222--1-6221-165C6-I11---25-5EF3Z4N11111112111111143332133362433MI---5344554533333442323442454961322332432246521-772625667673451646345IA77594633981C458888877b4334444344553241311154214512221462256333322544333511131143344434343222231211112131222-222354-272222222222-3--122-742213221111--1131-175762-251b8663-12117175411211122EECCDABCCCD-86667376DL-1SLMCONSVUUML223426G75355D542222222288A3321---------11--------------------44933121127666687344477AA4443445662431--645C-11143445A12323224211111111211-114-2-323-32---222-221-2352354534131-11111223121111111--1-223253151-52312333131111111121321-1311211111177375747665766666-6676769675667577775EDE798537744555567558543D54546562-466677747776111-2222244444-44D222334111113333----------B6443446362444447461--------12336222223324444656555551111--3122221111111111-12----1--------222---------14321466653S32 21--435-7331268A9A7D9C8FDG86656456462444335445859HBFOECBD77778233233212542342222333334568BL99AA7MEG763586716G5J8BBDA7545646589382IZ81A5925144369425544543A353684546BA13943D24829463q11156H88G8CC8AAD8AA * d.81.1.5 Glucose 6-phosphate dehydrogenase-like
[ 241] --5----1---11-91-2-----2------1---1--------21211--K11--2---------1-- 3BB5I87655753376566-6E224CL9MMJ3DCHELSEQ4EHKHB5D3775CBC28622JIB4OAQQOMB433353322H7611--2544613221--28233332-2---------------1221212111111244655C362526913112-----132153562---1-----1--568551-229ACDCDDGIK9GGIGKEH8AA9EECKNFAA546ABBCD6JI3222122422222224436372926746153BC1245555224488634311127733233313233--321-12--11-222---22213A8BE888AB897A75D991431D522-52421BDC212432512-2-11323B44F172162463894A474236666666665C-56637D94GC9-8AAB9APA888D7E86976AA89A599333333337641337511-11-11-1--12---111-1111-----69BD257877CIIQDDG6666DDC989F869FFLA89G13EE85B6CAFBD7C476632218411111122513753C752483256565165532344584764C22122112111-112111111112-1268882DD6667335878B594D87B6746A77---4215------774429866666767F5-57688686665667767757672532598866977777886683565333R1-443354334543---711111496417A44222635-333431215564824-31B5BCEF9CACBDBDCB876---------23448555555B557FB32422DAA1111--2244------------2-1----2-------------1---------------16851 -----1-----1121----2---1-1-221---21--------1--2212--1---1-1------------------------------11--1-------31-14---3----1212323124822A3Fo8194D11425333-24111423524221-1--5-4----61-1---1----11-511B11-1-6264- * a.6.1.3 DNA-binding N-terminal domain of transcription activators
[ 242] ------------------------1------------------------------------------- --------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2-----A-512-86H57GCFEHCDCAFBD59885777A787AB999CEAADBMC79CDCB89595365149369945-344775671228oI7BNB74647426H7-741t**y***tkxUm*w**m*v***N***kurf*t**oQvrkZ*vN*o*vss7DFKdMCe*b*ZEP61111141-1-1ACIJFL312CBBB- * b.8.1.2 SIAH, seven in absentia homolog
[ 243] -----------------------9E3464798--8-------1TW-8u18J69-------1------- 9EF13--1111----3311-141114111111311113413537E1---11-335------25-81-863-------11-1-36353-4442-1------7-1-6ABB6-1-1--11-1----1311332426H4ABBBDB53G-EBNRAA22476-2-3213B47MOS7------------932225551856666666617576554444667563CC3227322234A9-333333333333332222121--11--11-11--1111-1121111122222-22111111111112233323332333---111---12C81F767878948415996236221124--73CC662418825351-1183CB55B3212268VMH85BIFFJF44554544555-MIMILGIL4A5176579A6BA976B8545586BEAA475--------3983-cBP11-21111----------------------2572245434977CB694444CC9A67692AAFABCAC13678L9B9958DO5198F66FEC5-------54AFFU8iRE9CPI4lNRSG-OFPNDJSEP97D9JH6H611--------1-11111114325222DA3DCDI9CABCBCCEBFCDDD8DDDC7BK--2EGA8------2275-122123233311--221323112-321222231113227111-1111111112111111----11-3-------------14111114566A2L2B-------------1-22222221218EBCAD89A9C8988GBC81----2---A576587887789DA97544434571-1---d-KK98GF----------1--------------------1----24233-----2G-4 ----372-12--424316311-1121111-1----12------11133221--111221221121222--112-1-------1122-1311-1-1-21111-12-7-9B*6121--523-124263351BN32433312161334122-131-343425----3-3263-512---NP-----41521371-4DC4382 * d.110.3.2 Heme-binding PAS domain
[ 244] 553-54213423424282565431D44A64721-2-1354541-2253-1523-7A896455321--- -232D34455711233355-58225F5555539BBC47DG364B55432321533142--45816569765211142221-14--1112222-2----------11141--------------1-1-1---111143455--18433263335744343333454366431311111311112136733-3325564678735767678422226683335423222222A7422222222222222321114532231-33355112211-3152222222222233444445345332222222222222522111222217323444445434426222333424837432-45312531-311111321-122211111164NMM225B9996GHGHHGGEFGY-33C33B36Ns21ummhqkm**vvqH7-11EOVLGKOUJF22222222633213391111111111-------------------5---3-6GDA8EGHGFGABBB9HHRRDEBB7CIHP96A7-1888A4887B8OFEV336141194444444432334222B346931-633625241-25523343662221-4112142----------112211175B2613131B34444133444534335331--1213------7AID3958998A88888-9888889978987777876EFFEF3346766666666566666C55556572-9DEDEFFDFEEE-1-1-----222252EAP444886245446337222221112273BAAACDHGDDECF7FFF111111111145587777768A9922545444452222--122211112112122122422222-32333223332212441113433433454141- ---1------1--2--------1--------------------1-----1----1111------------------------------------11--------------4---------11--1--41261-23-1---1-1-21--1-2111----3--112--1--12--1-111-----112--7---------1 * b.40.6.3 ABC-transporter additional domain
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v*M6TLfGKHIOHIPGHLPJHXJITHUIJSPy*QbwPROEJ*IIeQ8MRL*AA9D9PH9PAIF9CKNONN * e.8.1.1 DNA polymerase I
[ 246] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ C99AFCA1cGB765445525555453531333355426364663434466536556656466666666356565467677666656455333546774652259A35BQ3y******sZjhn*u**h*k***K***RqlZ*i**nSvnab*VO*pxtpyIhfRXWJ8qLQ*QUJM698B*9A956KPVa6OC74AIGJA * g.16.2.1 Plexin repeat
[ 247] ----------------1-------32332234------------------1--1---1---111--11 4232433444422422222-22113312212121212333133422222331343322114523433553311112221113221222--1---11---11111231311111111111111122212312222221145---23654433322113322332334333323222223222254432--1253444443346644544334433464333422212221142233323222233322111121---11-----111111----1-111-------1111111111111--------------1--431----1-1-----1--------------1-2--311----21----1111-----32522231112-312223232331312121122122-2222212223112223322232323222142422223322222222211122442222111111111111111111111122221222233333232222323333333333432333333242422324333343242233333233333333333233322323111111221-2222212122222342121-1111111111222222211123222234444234345555445555555665651-22554---11144433333333333333-33343333333332333331334434333333333333333333332333322333333323333-13311111111143436222223-33322223333333333324443444443454465343333332333454432232343553334244233333311411111321111111111-------------------------------1--11-621 7656BCB1WCD5E9F9BAAAAAAA6BAAAAA9ABCABCACABAAA9CA9ACDABABAAAAAA988888298688589588889988AAADHBBBBFBBBA9EBCAB4CP9TQWMRLSIFHIJIHZVHWG**L6XRjDFGHMHIOJCKKJDOFEVIISJIGXWEE9FIJFGoFELB7BDL*IGH9DIGKQBPL9C9FFQE * c.92.1.1 Ferrochelatase
[ 248] --------------------1-1--------------------------------------------- -1---------------------------------------------1---------------------------------------------------------------------------------------------------------------2-----1----------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------1------------------------1-------------------------------------------11-------------------------------1----------------------------------------------1---------------------------------1---------------------------4--------------------1-------1-------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 221142B-623-44722232222222322322222222222222223333333323322222211----1--111------1112122346423244232731222-B*5*tt****qfpnpzu**j*g***A***rlgk*c**Vhxqkm*hb*t*ppvNMNS*y*WvZdZGK*I1A9FgAB8EIIFKS3SAB8WXUSX * b.34.9.1 Tudor domain
[ 249] 11-1--3444444444-21221143--2112135933877777EC65524JI8211-----3211-11 47G1843233323243444-43227A444445344444BD2768323-222185453311323244677521222111-211821312343572--11133133D2612---------------BAACBBBBCFB66699115186BB8AA588333354534445J9F83343333333331211111-125555557573675756544434666335252-5445438534444445444444434444212134112-1332244331134222111----22222222222222-------------21111111112667I222222252441YY2---1341-312C4NJBC24214512152211931333-11-1BDDFH414YEDEH44444443429-EEDCBD9A6B2-4556DGECB9CEB7221BA9CCBGA6555555555476337BK-----------------------------2434386B88798898899999AAJLCCCB588DL6678224559534388559842842246312111111337A94QL697F75ECFFB4CMEK8AACA97JBED8F21111111111-1-------1611255638453615526665684576636564337-1-659611111185CA55578887A8A78-8867A997778878878856A7C64477667666667666674975677772-55557554565511-1-2-1-2132A2935222222-111-32223443323123M2DDCD4A88C6B87CA864111-21-14287A5555538333444454543422221191441112----1---1-----------------1--1------112--1-111853- --1122--31-11-243444335969833433444323131334342325647813232212314525334443344324322231523222313213111-1544-2236362333122-12-63-335D3-236112-21342121-26-13211243641536-222234321231811125A8984A9123--11 * c.92.2.3 Nitrogenase iron-molybdenum protein
[ 250] 11---2-1------1---51122-322322211-2-11-----23-21131--1111--1-111---- 2135732344314333311-1522141111124536493628259754654336425522586364677532---21-11112-----566614222--1431233332-------1--111123131224411334411---5233553341433335334432676443323333243332323411-1445555545647686565444336772445334222224441223333333222343223232433334323444432343222233333333323354444444444443344243434343233333332252833333333331122322232112313512132-14---3312212311433212432442463214333333333334334-344565442813A7733343354424522--3443421111111111212-3223--1-----12--1-----------211111--3-11-111-232212-11154431111-13352235-1---36211332443224231142-------1442342141-1-2-1122--1--3-2132123139-1-212112--11--------1113-2325533215544633333354433453443461-24323------5544245579B59A876-76577565677975555556774437665455545444554557554658531677767777665-33-3233344443-544334455334232444-1-11--1--22---1233-222231346211111111365577567556766452131222211111112222222111111111121-111---1-111----131--112221423332331-2 1223DD6-I7A3357DBCAFAIEGGHJ76B668D9869787AA997B9FKEFNGDAFACBAD86777867956A7684888777675766L9BLAPB9A76AB99C18YEOJKHFOBDA9858ALG7L9g*H-KEd7C9CFEDJ949B95A8AECBA8C8JN8HVH5E6346B859CDA*9B98BOVYdITMC79I996 * c.37.1.6 Phosphoribulokinase/pantothenate kinase
[ 251] 11111111111111111113113---------11111111111----1-----11112122---11-- ---1---------11--11-11--1-1-111111-1-----1----------------------11------111----1-------1-1----------1-------1--------1-----11---11---------1---1-------------1-------121------------1-1--11------11111-21-342213--1111121---2---2----2--1111111-11--111111--1---------1------------------------------------------------------------1-1--------1-111111---2-1----2-111-2--1--------1-11----11-1--1-----1---1------------1---1--2-1---1---1---21--1-----2--1----11-------------11---------------111----1------4--1----11121-----2----11-2-1--------11--1-----2-12-1-------1------------1-1-21-1-11-2-1----2--21--211----1-------1---------1-2-1--------331-1-112--11111--1---11---1-----1--3------13121211111111111-11111121111111111113431111-21212222222222121111111111111121111123--2-------1-11-1-----11---1---11-----------1-----1-12--1-11------------1111----------11-2-1-----------1-11------------1-1---1--------------------------41323---- C778LGG-nLJCJPKFEKEAFJGEFGDGGFABAGCCCD9CAAFEHEABADCEOF9BDKEEDDHDDFFF99DHB9DCD9BGADDDAC9B85CBECJJ788C9DDNGJ3DHI*o*jsxrRJNPMcT*wP*Q**i5*g*JUONoPVmTMaNLEcDDyPhUUbFNOKQNL8jKSNRULHCGO9*87886fSYiJYNDEHGOUC * a.47.2.1 t-snare proteins
[ 252] -------1-------1-------1---------------------------1---------------- ------------------------------------------------------------11------------------1---------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------11----1-----1---------------------------------1--------------1---------------------------------------------------------------------------------------------------------------------------------1-------------------------------------1----1-1-111111111111111111111111111111-22111-11-1111-111----11-------111111-1-----------------------------------------------------1-------------------------------------1----------1------1----------------------------------------------------------------------------------1111--------------------------------111111-----------111111111--11-----------2111111112---------------------------------------------------------------- ----11f-------2-1211112--1211----11-1----------1---------11-1----1-----1----1-1-1-------1-2-1--1--1-----21-742*******vksh**x**m*v***9***dsyl*o**vW*tqg*jW*y****JQPccbXQoOSpRocJ----611--137AH1A2-123112 * b.55.1.2 Phosphotyrosine-binding domain (PTB)
[ 253] -------41111111-------11---12-31-----------12-----4-1-----1---11---- 2-82S523444143DEF88-9O55NH89989FMJJJIKRU177B75462894A7844A--7777PCMPNO42111111123711----11-1-2--1---7143B35-2--------------15433575352577787--1C2723833242----221-22-586932--1221-11-2A27222-1413777786BB4A988773133458C7121373532222264311111111211112233122522252122154113311122421111------2111112111112-------------1----------2-162222122323-411-3211111-1122-53----231------218-2D77B-----64BAB--26576633233323325-359556493D829668AB9BA95795356475446257611111111533-3444--------------11-------------233A5-576459888A7B46647776796749C7B8CDB129AB3356677A48426622214522222222123376C2211-1-2-----23122-2-17677EE23--2----------------------22331352835135556559665647678496---2213--1----132421111-12-211-11122-121111111-111335233311111-21---1111126--------1433333333233--1------4445167231------11-1-111444343211253BC9B7B7CC958866671----1---2-215222123222278C97986773222--12332211--------4-2----1-31212-122212111----1-2-------1411 33129A9-B412447NGHDE9DDFGJE787755ABA5787787674DDLbIPWVIHJJBDCB775135352595553211377677411KQCGEJA63636E8775-7nBdBBB7865546156964C3Xb5-74E564247943466433336673997853A473A7D287BC5E86J577CEMKKOHND8ISPJY9 * c.69.1.7 Proline iminopeptidase-like
[ 254] 1122214333333334-433222233333333222322222223232234452212112113342-33 4353545566744444444-4433464444444455358934333453444466643411657564754432344333212243323244342523-1246433433331-1-11-21111111222433222333333322244334333443333433333333443333333334333354433221244889899A96899BB9745554A8833454344333337533333333333333334433122344323225433542424322222221122322122112211211111111121111222322222352-56444433322232443221323334422344423144244443212434444443224457333335634355555554545-66556745C6345665576657758B433556453745544444444544333342223333322111111111212221422333553344436655556455554447778766576485724544345347586574333222534544444333544534443462645563433334554443467474484355664534333333333233344463343346355544352322343223453-3333322122264656555444544455-4565846545444445446566874464444444444444444555455544355555555555522332222265553444544454444444444455566353558388887877477665665444343434343354444444545334544444433332222553333---111112-1----1---1--------111-----22222342333526 2244535-8342A952976A7A8CBB77655656755A8A8866665955687A765664763475444544945543346646565657D4947B6443476655-4A9IFD97DC5796445975D5T*D2DBL648A748A8374568A596D7386747BA88A87CAAA84394k45745G58E5B754A9875 * a.127.1.1 L-aspartase/fumarase
[ 255] ---------------------1----------1-----11111---1-----2--------------- 1111111111111111111-11111111111111111162111111111111212111111111111112111111111111111111221111111---111111111111111111111111111111111111111111111G332222112211111122-12223111111111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11--1111111111111111111111122222222221-11113111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111211111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111--111111111111111-111111111111111111111111111--111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111-111111-111111-1111111111111111111 ---1A68-425-8699A374457868565878836544546556557667976666866767335333234544353233334655534495ABAF6465233453-4E9uysmvntWWbadjZ*tQ*U***1*y*ZWZYrUcmcXcZUQlXP*TwlfmGRWTUTiJqQRbFPW61372333375LUbr5YN1225761 * d.50.1.1 Double-stranded RNA-binding domain (dsRBD)
[ 256] ------------------------1----21--------1----1----31211-----1-------- -2413-------2112211-1---111111112122132-11---111-2212151-1----4--123232-3331--1--12111--4453-3221--13-3343213--------------13-21121212-2--22--13-111122-11--------11--2231------------222----1--12222323333322232-1111332111111-2222221213333333333333332322242222233331122-1-322221122221---1112222221222211111111111112--111---111-2133322221211122111122--31-1--------2----121-12-242111----1-111111-----1--1----1----11211121-61-1--322-113--11-1-1--11111--------------1-1-----------1111--1-111111-------1--111111444345-----1146222222555313111332-221131-23-2-5---2-1--------1--211112---1-1-2211214221132222276-11----------143222322----111-112--21-1232111-1432212125151---1-1-------132--334556455555-5545554545555554554324112211122112112121221444543341-433333333333--1-111113232-1--31111211111111111-111132222133332411311-1-21--11111111-2333-----3222233333332221111------1111--------11-----1---2----------------11-1-111121213 1---987-B23112A4566565568634455345546866577445675674B923843444666465377773A68577588997433197599B53672345731938v*****rSSSNVhT*vOpX**v3wh*RVOTmVbtlKbTWNkQN*Teha*HJKQWciIkYf*ReHS4222421254EBEB57832G7CC2 * b.1.18.11 Arrestin/Vps26-like
[ 257] -----------------1------2111-111332--------11----13123-------1--1--- 5556555455455444344-44556444444545455466544674564555555555444445445466555555554455444444666656664--579767796744444444444444766666756665555661118667556764644444454555677555554455554447444456475444646476547544654446564544586555555556566666666666666666666455644665655555445454555445554444455444444444444444444444444466555566459756666665666765554665575555457477755568556665455552544555555554445445555455555555555-44444446555575555645645645465455555544555555555455456545511111122555555554455555545555556597677666666666666665666656666888857886677779777977765656676665555797556665564455444444555543556556555464544455455444444444454454665566658567656666566666656766554-5555614-54555566655555555555-55555555555555555555655566655545555555555456555555565566666666666554644444677755675666666666556666555655665665556566655666655658888788886665665665666665554644555666644655555554445444455---1----------------------57454454345559 -1---2--421-221-2-1232243332252223213424443221231111123423221122213221221121--1-11111211212322231111232213-2--142211-11-1--1---1-8A2-12311-11111-1----1------11-1-11111123-33222144A42222C356178324232- * c.59.1.1 MurCDEF C-terminal domain
[ 258] -----------238D--------1855321B1-----1------5-229NH15--4------11---- 3--83--7213----------5----1-222-6---9-K8-3I8--31----1--1B---14--12R8FA--1112------3-----221D-1I*C-------9--3---------------A---91C--2--1DC1A---1-g3-G--9-H---------J89AI38------------472-----4E-----1----1-----161-I-D--N6B11--------1---------1-------------2-9B-1-D-B5--971----3-t1-4-E----214442412-12-11--41--654-----113----11---------------11R-----7--9---F19322D---1-1CD--6--34AB1-----D-L-EeO21-6-59ACDBDBc9HB-7C24-mD7-E--B12AA-CB15C444---5-B-c1--15bbbbbbbbAdWd6-73-------------------------F-Lk--3F82----51658-1b****GH2DA8JH6E-XI-735---5Q2HJU6-K322C--6----45-15ABL-ONJP12-1-952-1-D--1-----A74--Q9---51----------------------1---3---1-6B-1---3-D2638--34441D--2-----2-1A---------44--B---I--4----2C13-1-----4-1C--1778--4L-1------1A-1-1--1-1434--49-2-1--11-1-----6------3352L-B-2---------------2--32*-B23I-1-----2--33147wh33Dg----UD-v--223233h1-15--1V8VN***------3---11---------------------------------------7------------ -2------1---------------1-------------------------------------------------------1---------------2----2---------2---1---------------------------31----------1-----1-122-------1-----------1221-1------11 * d.3.1.17 PMT C-terminal domain like
[ 259] ------------------------------------------1------2------1----------1 -13----1111---49844-58--A244444554441322-234---2------------335----111-----1------G111--1111-1---------4-1-7-----------1111------1----3122-----2-ABI555621--6742734217-1-N12-12216-312--------1--111111111112111-5---11111---------------------------------------------11------------------1-------------------------------------------1111111-1-----------------1-1131--3-1----------36113-----22143----------------------1--2--357----61-4---772153BA548266847222222223541-4-A-----------------------------239B2-1-----1112111-21--11232213211121--3--31-2---------2-2---1----------11-1-41415-1--411---313--412----13-4-------1------------1---542-2-41-21B24-211113-1---41-1-3----B11---------1--1-----------------------------------1--------------------------------------------422221----31811------------111----------222---1-2-----11-1------1--------------1-1---31312234------71----11--------1--------1----1--------------2--1--1--23-- ----C8O-----11-33211124434534233244433431224551142666511113---1-1-21--1---------1121-1--1-3131-2---1-211-2--*-*u**o*mRXPXVsW*sd*c***4xk*YYYSmTapaIbXaNnUP*Wqh***omB*ovNURTUB8m43HG5X78AI-5XMg2M8RZ4665n * c.37.1.5 PAPS sulfotransferase
[ 260] -------------------------------------------1---1--11---------------- 4472D2522225-3D7ABB-BB55E8CABB97B98AA4681MGG1111121121221511DG11N6MJBH3-------11141121124213111111-24222L35131111111111111121111211112112211211C1554598A1111222211211CF9M21111111111111111111121J3332332262223411222272232312111111111B1-11111111111111111212122222212123222221222211133322222241111111111122222222222222222222222122733333333334G25521111-5-11431111311211111111232416422222222746622224734233333333324-556587433511223A445544876733142243442232222222223324423111111111111111111112111111111223213232456686GAJLOI4464TNST6Y78623441255B12311234583214211241112111133523915745123422222-889833A2B2222Qj43233111211111121111212111233471-2A4223788788B88788797797971-12441-1-11181D41232558266333-5333335354557222334113538742222322232223222423343231164344424324211244534432223182511114111111133144774151115555468B471212116775111111111233B2222253855333232222222221112221111111111111111111--1---1-----1-111-11122122222222413 21-1hg4-512--1DKHPHfTSUVfSi675878RYIEFGGBFF988TIJRRPTOKNUZMFCE2221111221212111111222223539E7H895222132C554-2K6H776762355355474392Cq5-67C23427255334411632A365452122933365BE3A282BH4a642EG9B9FR8B3333328 * a.28.1.1 Acyl-carrier protein (ACP)
[ 261] 33131145444444442333333342246343333334333334333333443333323133213-33 4443644444443455444-453355444445655565CA34453433333345445422656334358733333333223333433333433422233254554433522222223232222233333333333677793335444454445555444454454566554544434434434444533245466666466466655544444476544544443333335734444443444444434434321223232213512221224324442222222334222222222221111111111111322333222234454444343434334443222423124335556445334443333213354444433333344563333334333333333333-3343333343534333334333334543365455445673333333333343333222333332222111111111111122223356335333444464453334444644442486866973355447363454535434333454444444434347A23555444444444456545375655554336423333333333533333333444533665663656876866666776666676767113363432233376655656776666677-775786776776777677799865555555556555655555576657567325555555555552233222222232367673334234333332233333333444A4666676668779A766632211222256667777777777734333333333333335344333311111111212111-1-1111131111111112---24332333333333 1111222-534222433434656654544333334343233333334437336343334343363364434453576567333333844353343A64533534581472427233133212A1W*2I2Cu4-42N1222c33A3121224--A2323431425212511954415558*65665LARG4A787AE886 * d.81.1.1 GAPDH-like
[ 262] ------------------------1--2-------11------62-24---------1-----1--1- 34A2521222111111111-1111121111112444322116665331344242322111673254389A5211123311152211----11-1----------22112111111122222222---111--22-ABBA9---D364498741133------55346548------------11322--1233555554453545434354434454242421122222262111111111111111222221111111111111111111111111111111111111221111121111111111111111111111111332442222222422322222222241222433233343232222221-35-2----------22-----1---1------------1111-3-1-2--1112-111----12-1--311121-12111111111----1---------------------------------11------1------1------111-------12322--1115443344437234523421----------13771A513112-15--1-23232-2-122224M14-------------1-1-------21221122152-212-----123---1--21-32---1121-------3----2-------12-----------1----------11---1------------1-1--1-------------1----11----2-----1---21913------11-1111---------1213433332223411113211----------211211111-1222112131122211111112BA6555--------21-----1-112-111---11111111131-1-1-111122- EFDFGEG-mGE977B67999BBC9B9978779877788888888997778D999677977778897783B98989985988888A87876AC7BEC66686B6EIW-B*EWVZPSVLIHEGKLGYSEWI**R6YNmCGEHTGIPEGJKEGLFDQINKKKAG8JJGEAOCIPGHKD6UcG*GGGTPp***A**NOYbVTa * d.219.1.1 PP2C-like
[ 263] ------1111111111-12----2---1----112---111112-111-2131------1-111---- -111422333222222211-12--131111115434364424435443332434323555452233656853222333112-----1166562423---1314522515-------1-------11-222-1-32----2---2-31-3242221111111111122311111111111111325----11-1111111-2-2121211-11-1121---21--11111121--------------------2311111121211221111111111121112121222112331212221111211111111211111112-1111111111111112--122221111--2--1111-111----1-1222-5333543322243333224335433333333334-4534433354314663A8497834322343534244533444444443333222411211111113522222232222221111142432322234333443322333443222243333233222333433332324222224222322222222222325231311211111121-1--1-4221317612111312222121211111111-122223322244333321111132121221241231-25113------32322222222222322-22222222222222222222222222225232322222323323222222221222222222222113111111222221543111222211113112222222222222445443342343442231222222222333322222332335455454334333311211111111111111111-------12-1---------12-222-----------124 3611h16-624111334657131226222232311212322322132R434672433l3323C22222-32212252122253823232466433522224D35h*14ZNddMDGX56556766KP6d7bwE-7896687977b957746*52Z796D*BPD*****511655*65Fw6O554A7EF7t2FO2944797 * d.151.1.1 DNase I-like
[ 264] 331121222222222322213131245433421-3---1--1-122111342142225222121--11 3542652433413222133-3622242222215316445524465231423166634411533621685314333344825611-22-5554-511---23-32-232-1111111211333321111111-3-1111122222254961144533233332755376933332111322325562242-34BBBDBDADA9CBCBBCC999A8ACB545677ADDDDDC78577765767777777676797D96BB67B7BFF559AA89576ABCCBCF868DBB9A88999A9987788888878789D99DD8677G3329E4445546A5A394468A72427258524635462242222253362133--2----1411245231363222131322223-3422723213-2511444431-33-1211213----2311111111123311112------------------------------11-3-33335433333134435644434334544112312552-3134372131-1623116411111112425-633432251222--211121--123--2-67161-----------1-1--2--1111344546463112181---124-2113---1212--2312311-1128A777A799A9998B98-9999999999A9A78987A8AB78767B9C9BBCB9ABBCBAA799888882-98888888888811132222-23344233555564432212444634333342433133352313333332333211112111655565555564B6623-1-11212----12362233322222222232526416-9566A6366668755722222132131212441 5566431-PB82259348746455365446444445244342275542469A7E134441223321322221333332332331434353554714231432226E12G8B357426322222377491AY6165C2123453551334133266624C232261533311684349C5W56769LHLS6KF9C75927 * c.108.1.10 Predicted hydrolases Cof
[ 265] ------2-11-11111-1--------------------------1-----------------1----- 3-32G4478891117A666-68--9j656667CBDB9Kmf1C3EHA914564LLQ758--11C4C7UNJF81---1----1-H-----11------------1-212-6---------------------1-1--13353---16----------------------11-------------5-211-2-624444443343444334C38824445143182-2222215B211111111111111211121-1-22---------221-----1111112222-11------1----111111121--11--2---1111292392223333131463322126322-16422AA2431-1251112-2-1-1B993-----52OGH--892372FECFEFFCDEN-68M66Q7JRa2-rZZOXVbjcdfcQK442GFRGCLNFCF222222228551-4-7------------------------------14E2-DZUHNLJMILJF8884IIaXCA8867MDhKSSP24A99A8A68PAY8YR695----3-2222222---555-4E353442163331424123312-----115-11------------------1-----33646844C574454546665666474655----2-1------8BG95B4DBBDDDDDDD-BDBDHDEDECBDECCDCCECDCBC446E9FBEBFEEECBECBCD999CDBB6-566666666666---1-----1----45KC1114131222213329A8A84911-84CCCDCGFNBGIIJ5HIG----------334833333557563322222----------2--------------1--------------------------------13121--1- ------1-----12---------------1121111----------------1-1-----------------1-1-1-11----1--------1------11-1-------1---------------1-13-1--2--------1-------------523312---1-----1--------1--1--7-----2---- * a.78.1.1 GntR ligand-binding domain-like
[ 266] ----1--------------------------2------------------------------------ 7742o11577B11112211-12--1E111111422235EL7-2CPhQ-IJD4TQU117--968AU6OQYL6IBCCHML4---2-11----1--1------4-319-749------------------------1-67854---C----1--1--------------1-1-------------68222BA-C69AAA9A87B6A99878EFCC899B767C28669BBAAA4Q54444443444444441257C791771A527BB88667529C7455777987855577777777877654556666555555744377779527E22222229295622468AI423122A--------I1-489991131-1FCC4-----5-654--------5545455545C---3--5-35J--YLLFXSSfeZUR559158E94544966--------55511--1------------------------------39271255248BCCB87433388BK65654799A2554--666B161144926F----1--2----------------1----11-3------------------6-----------------------------CCG6-77-94A6565734333412233115-------------JKJH7JEEEEFEFGFFD-EDBEHEDEFGEEFFGCFGDPQOKJ88BEFCDEEEEEEDDEDCDSBADDDCF6-JHIIHHIEHIII---------------96D444759133334336------1---9744443548244451776----------A9AABBBBBDB9FG659A9AA7881111---2--------------1-4----1-1----------1--1----567513B543-I-1 -------------1------------------------------------------------------------------------------------------------------------------------------------------------1-----------4--------------1--2-2---3---- * a.35.1.5 GalR/LacI-like bacterial regulator
[ 267] 11---14143333331-1131217-33-1-2211---1-1-11--1125--------1-11-2-1--- 1661722855842225222-24--55222224534428CB24432212----544241--1163445336-2----------2---1-32322277---223315-4241111111-----1--22243222422---32---21111-----1--1--1-1121111211--3-11--2--33234---4-5444443541445346123333441312663-544443523222222222222224--13381233214644411452-1322321---54441332231232222355556565633661111--1114-754A111121262616662413-9-2--126-BC3B8I4541--3118-1-25551----156A434377A55545364554545-4464486425226667535A7644473415364545221333333336333-24711----------12352212--11----1115B214AA6A566876789997698888847A7GAAA61487365667A83F59335-1--131111111---1473GN52-23-------MGJ4H4655555545AG1-12-11111-1132333331-1----1-2561545624333323644433323471--111-111-11155965439889998989-89899779A8888AA9AA7BB944452B9A6A9AA98A6A66B67625568-1555555355555---1------111-22151-144324532-22289A6857443B-67665677356765676---------1--14222222-1216789798443------25331133---1-11-2-2------11---2----12--12---31211-3----223 2-3AA67-C43-3553A78DCB9FHD96676667455697686655BC6CADFDB95A578A988447286677658375454577664AT7A8EL65669438AA-7BCFA67FAJ6AC9483GB4A6GwB-A9G588A678VE35745354PB874D47S7G6B8R68ULDG91422521241874JAGH66JKFA5 * c.124.1.2 CoA transferase alpha subunit-like
[ 268] -------------------------------------------------------------1------ ---------------------------------------------------------------------------------------------------------1-----------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-----1----------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------1-- ------1-----11------------------------------------------------------------------------------------------------v******dVhYb*b**W*b***3***Ljab*Yi*nUecUf*ON*YiJa*7A9VGcQRkMEXBMAB---1-----------1-------- * b.1.1.2 C1 set domains (antibody constant domain-like)
[ 269] -----------------------------2-------12222172135-211---------------- 4CC-J1-54442223DD99-9F11C7999998ECDCA88D38576721433-45612---756-O9CIJE7-------212161----2311-311----3-335852533333333333333232244237443WYZYb---u-D8BB776553345545579318CB9233322232332112----114B4444444524445446577BA544264462399999843111111111111111122121----------------------111--------------------------------------------23213222222222222112222223112426332433421151132-1-2-4-221-----54AA97134322611111111111-83433224432133353646563337414435574437322222222-333-A36-----------------------------3126112434253354563333547B3333234434847222226464464534377B6414741111111442467288353892DF887353452242833645*3631---111111-1-------4122322754465434456656565565554545656--25567------35223223333333233-3333333333333333333455443334333433444333343533333331-523344434444---111111555563858111222211111222645552523285666669866789898883221222225554677777565BA12988885541111--L6QQJJLM1111112233--------------------------32-22222222421 11115541311-22544733333433433243334444444444444445756966635545344333-3443334413532233433446343454343322A78-2E-A9GBAFLB995BDAEH8K9e*L1QHIBA78L8AG94D978J86Q8DEBL5CG698C5BAAH78222332Q132544BAH5E436ACJH4 * c.13.2.1 Anti-sigma factor antagonist SpoIIaa
[ 270] 44848435544455534544544444444444434443444442444444444444444442448-43 5844434466644444444-444444444444844444444444444444444444442265C45466444444444444E863444433443322-222424444446---------------44344433334444444444454444433444666546454455544444445434434444444254433333552633555344662356244435464556444426666666686666888644724211232223333215164428665552444464444444444454444444444444433444333444248676777777643334444415834746444444443464444424436644434115444664444444444444444446-44444444646474445747776655244644454444444444444444454454423344411---------------22324444445666496666666666669888886867B44344344454633434374444444555333333344444413444464644444344444444444444744444444444422422222224444444755444464434444444944444444444126644632233358335537557775755-55755575755555555553333333355555355555555555333333531333334333333222622222222244646222222222-32--244444444544466666667666668466422222222433393333333633444444444454443446444444222222223---------24-2------241-----34667444544443 22-1113-725222544524444424554444444454442445554544644545554444446644454244644-44444454435544444355546436CA-562868779C5554653A9345CN5-8664445435544453454374562535429742132943623343W44333936C5463464445 * c.78.1.1 Aspartate/ornithine carbamoyltransferase
[ 271] 21-------------11-------1---112-78511111111--1----1116----------1--- 6556555545556554344-45556544444556665566555854464555555554555545555557565555555445554445556546664--56765667564444444445444455655656655666688111A8677677758555565667766A7764544444544447454466574645657466567644554555565544496554444545465555555555555567776555555565555566565555654445544455444444444444444455444444444444555444469777666666666665665776467646466598656659557777554443444644444544454454444444444444444-444444446444444444455444444544475544444555555554555454454------224455445555555554444456554776775555555555555555555555557777577757777787779788755555755655558A7557776564445445444455453467555556584444444444544444444444544556555557765556666566555665667664-4655514-43455655556776665566-78667666667666666655555555555545555555555455658555654555555555555444544444565655574666565666655556555555655555555555555555555569898788885666655555555555555555655556544546666664445444444--------------------------46444454455659 ----1---2-11----1-----221111-------1--------112-----1111-1---1-1--21--2--11--1--111------1--1--2-1-11-1-----133311133-11--1-11131371-32312--1-111-11--4112-3111--3-32--1-1-3242-335c333228346-58-13123- * c.72.2.1 MurCDEF
[ 272] -------------------------------------------------1------------------ 1-2---1----2---------1----------1-------------2-1----1-------1---------------------------1----------6-1-5---2-----------------1--------1-------------111-------1-1-----12----1-----1-----------1---------------------------------------2---------------------1-------------------------------------------------------------------------------------11---------11--11-1---1------------E4-------------------1--------------1--1--1------------------113-----224---------------16--------------------------------1-------1---------------------------------1----11-1----1--------------------1--1-111-------4----1------2-151-------------------------------13-22-112222214--12A3--18---------------------------------------1--11----------1--------------------------------------------------------8-1------------------------1-6--------------------------43-1-------3-1-----------------4-------------------------------------------1----------1-- -----3K-1--1----------------------------------------1--1-1-------1-------------------------1-----------1---2--**q*******t**q********7***v*v**zy*Wkv*s***o*u*Z**AJJTeuEM7KDVBBb3---1----------1---121--- * b.1.6.1 Cadherin
[ 273] 2212137777777777248373677777727766666676666666677566661111112668-166 2236938544448388888-8822897777788888788839A832223111333223--88B8AA9999811111111226622213772726671113423383413111111111111112782732322776777732431778788787776766663779887766666666666666277111384555554444455445534444545888831266666684333333333333333444431111121111111661111111111211111111112111111111111111111211116111111111287787777777777677777788721116677789772168774221662213444111116886622388888777777777772C7677B77282-888888988899674329988888A897777777732226838--1-------111111111111111----13A33333335999A999888899A98888789994444243374E7448A838344734449422433334434871662626666666626667676C722222626211111111111111-121122123225384336132443333644333443434A41-1247211111264336232222222222-22222222222222222227774477466666666666666664222222221932233333333221511111123162736221212111111111222222223333888877887888848881111111112333533333658551144444222222222634488771112112151111111-111111111111111111111166111112222 1111123-844122522223322232223222332323222322232423333424323232324223222322324222333423422362242H555223247311614142144322213287282Hb6-5293221323612212232243542513323131222622345445a4665475593842535365 * c.90.1.1 Tetrapyrrole methylase
[ 274] ----------1-------------------------1------------------------------- -------------------------------------1--------------------------1-1-1----------------------------------------------------------------------------------1----1-----------1-----------1-----1----------------------------------------------------------------------------------------1-----------------------------------------------------------------------------1-----------------------------------1--1-----------------------------------------------1------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------1---------------------------------1-------------1--------------------------------------1-111111-1111111----------211111-11-1---1--------------------------------------------------------------------------------------1-1------------------------------------------------------------1------- ----64Z-5211--222442222343222334442533231333333544224243-2111223464442363624313433232433346321342321-324361843*******fgganfl**e*e***4*u*edea*hh*YXmeeZ*bZ*d*rnnio*s*pgJlKLY***L243-1----23254445-41321- * c.45.1.2 Higher-molecular-weight phosphotyrosine protein phosphatases
[ 275] -------------------------------------------------------------------- 9AK-------------------------------------------11----111-21--11-----11-2------------64356GHFC-F13---4G1C7J9O7C--------------25257664468611111---2-5934553--33333533342C3482-4-----4-----2211--21413333333323333232222313314223142------8312211122222222212222-----------------------------------------------------------------------6116-------1-1-1222--------1-13211633224-2-----42F3DH44B21111AFLNRE7DKKHEE44454553446-MQJFOMLJ6A7-F99GDCCDDD798G588656555463344444444898865B711--1---22--1-221121113311-1-2218748866ACKKKKAA7666DDHGBBBB9DHCGBEDL-4DEF7BC9BME8796CGF8FBG8A11111119698AE848256955AB6631866778B78AA9BC61A921113333223232233338544B8D886LEBOBID4FCEEEJDLIFFHKDJOJNH--1B549------B6887D8ABBCABBDAA-8BBA9BCA7B9CAAAAAABEED993479858999999769688B96875882-788878876777--26343336878FAF761111111--------777774C332C9EFDGCDEGFAEDCACEF1111111119356A66666BEA9AGJA8C8879A654543B7CC36EE11121222---------------------------------111117D84 -1-----------1----1-----------------------------1------------------------------------------------------------------1-----1-----11121-11-----------------------6----9---------2-----------4--9--1--7---- * d.225.1.1 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
[ 276] -------------------------------------------------------------------- -----------1------------1------1----------------------1-------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------1-------------------------------------------------------------------1--1--------1-------------------------------------------------------------------------------------------------------------------1-----------------1----------------------1-------------------1---------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------ 23-156A-C371337226-335322131112223222212144-111143332523432232344221222-21112-2213341322234224712411137-32-I8Az******iggTjum**Y*j***B***bthi*gr*kbpknX*fa*ktiteTgTPVGLMvLNqLUSF14429-1212B5DE1G661GE9F4 * a.39.1.7 EF-hand modules in multidomain proteins
[ 277] 33---25344744335-233332-33322234211---11111------1111--------122---2 234-641433333264244-4A1144444443578749EF34-2211322217553631165724535781---------1-31111133231133---36675976461111111111111112323322223244433--1433122232--222221112112225211111111111146444--1724555555566656555364445565466463333333355255555555555555544471-1-22-2---11112221--1---1111-1--111---1--------------1-11--1--------1122211112111-1-3-22121133231411--11311-13--1131-215-465551111244A573235685923232333324-4564474245915654546456557655967922224672222222222213576--------------------------1--143572576497667679666665AA66665697B979B13888655778899962241111633333332112787514144631343321665384564B95B884233211222222222222222121111155278574773988887A8988898888A9--2321211111144342453445344333-4333333333434333334323443343323333333333333533333331-433333323333---433333333338568222232222212332556655656365BBAB98AA8A8B9555642222322214556444336565577455453331111--31864488----------1-------------------------22-11-1-1-1435 2---575-B4412276B86D9BAD7DC7779896567555255786CA66859464525655754423-5--633-----322364-23683B9A556445145I7-7E7iFKCGNB8A8A7A8IG6J9Y*L2MFJ79A9C99B789898893C79979BII8e932B67569AN5773P65596A55C7A934ACFF4 * d.38.1.1 4HBT-like
[ 278] 22-1--243333333211111222211121231211111111111111122111-----------111 46D5522422332384566-64229F66666788788EIF28385231144274422211355237D5453111111111215211112321--111---11214423222121222-11111121122111111655332211523442242211111211121344531211111211114442211151133333433233334431422133332333222222114711111111111111111111412122121111222331111242223332322122111111111112322322232232122331222311121111111121121111---11211211422211111222423121171365571111123LLM224E6AF44455454243719CBA676D5B81C44A55568765L91724655455556656666668442322211111122111111111111111111111235D11BHGBBC7BBBD68899AAHC99894ABEE8EH8153434675586B3C8551112112111111112214424342122112111112121112145445824111111111111111111111211122223232-131411111-111111-11-1-2-111332------1133--2-122-111---------------------113133-12---1-1---1-1-11-6----------11111111111----11111333325527---1--------21-44444121221454643968345642A8B1111111113111-------1---1132222111----111111113211111111111----1-111111111111111111111121121113211 1121432-K333--4KMULKMKHPMPSGGCGEFEDGGIJJKIICCBNHGZPdlrIHHE6DAAA86355662793A75255455577244EPAM99B564C46722314F4i8AB4973222343A7483Ku9-96B33337425424242442936A695775B48CD6DIDFC23554n6547BIKHOO9F4333455 * c.117.1.1 Amidase signature (AS) enzymes
[ 279] ----------------------------11---------------1--1---1--------------- -1-------------------------------111----------------1-1---------------------------------------112-------1---1-------------------------1----------1-------1------------1-1------------------------------------1-------------------------------------------------------------------------------1--------------------------1---------13---------------------------1--111-----------------1----1---------1------------------------------------------------------------------1-1--------1---------------------------------------------------1-----11---------------1----------------------------------11---------1-----1----1-----------------------------------------------111---------------------------------------------------------------1-1----------------1-----------------------------------------------11---------1------------2---------------------------------1----------------------11----------------------1---------------1-----------1- ----1---2-31-13-2-221421-112121113113-113-12331--111111-3--1--2--11---1-----1--1------1--3-222--------111---3-*******hilkkwj**c*m***1***cieh*jn**UmjgXsbc*n*roqESRaeXPNjOO***N7-2---2-21-2334-431-3-113 * a.123.1.1 Nuclear receptor ligand-binding domain
[ 280] -----------------1-----122223323111--1111112222222322--------211--11 4362422233323233378-7533357777725656434432223335344434433433434454334534444455323322233244543544411444644454555445453344444533433333333333342224233333333333333343453345343332333332333222222223333333334333333344443333333324334444443454444444444444443333445333334445544334334343333333333333333333333333333333433333333333333323353555454434343444333333222432244423242223223222526344344534344454535555544444444444-55356345453335544443434433544443435445333333333344333332223222211213333334334444222223433366654677667555554454555533775864533887353333433563532344445444444333554333243322311113223244222222277242222222222222321222221222445556566555566555655555655556562-4776621122255567555555555555-5535555555555555555555555556565555555555555566566655255555555555522765555544445555655544455533H555444354344355555555656656655553343433434655655555555654344443333333333334445444443433332322213-333333333334334355422222222224574 24233321A33333332312254432112111142221213312224541522443733363152221-23213413332111122121223232312211522232273DE9BBK89588879WN8C7U*B1F7I8786D86C795757I45CBCB7H37J376G233259EA43232G32454524934354A5262 * e.11.1.1 Type II DNA topoisomerase
[ 281] 112-1-212222232121111-1-93323174333-13122123314324666-11---112212--- 2-122237556554444AA-AE22F3AAAAA9C789455622452446611143B234--43614142753465545511314-2122-11211-1--1-1232212311111111-1111111211121-11-122273--136-4353322-111111-112214121---111--11---32221-12324444436424454443122224462211112522224123---1-1-12---12132-185636551235772245422312678-------21121222221112---------1---211222222213416555658655535773112422444231-2262-32212523323412-5225-----453365144332322222221224-37414A54746-2112325731457A-415155444113--------311-1334------------------------------2411--1--14333332222255233222133343456127833337744134131633231-1-22222-2213311412122142334-22112213-345314512131122222131232322313-133511311121213-3221-1211122211231---2215------2222----11---111--1----1---11-1-----1222-----1111111111111111-------1--2-------------1------2233412------1--1111--1--------221444456154431-212323---------311121111112-1121--------------2344--21----------334441--112-1------2-11111113-1111113542 7777GD9-TCABA9A7BA97BA9DABCCC8A9AEBBAA9BC8B9CAAB8C9EHJCAB86A9A656884-661877542356887782425G7B64D5536565PIL2EGHDFNJMDaNBCDBDJRWGP7u*K1VGjADAHCDADB9D88AHE8XDOEAJ6GiK95B4XBCfKQAA5DC8*B87BEAEISBHD87FIDGD * a.23.2.1 Diol dehydratase, gamma subunit
[ 282] ------------------------------------------------1------------------- ---------------------1---1------1-1---------------------------------1----------------------------------------------------------------------------------------------------1------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2----------------------1111111-11-----1----1-------------------------------------------------------------------------------------------------------------1-1-------------------------------------1---2----------------------------------------------------------------------------1----1----------------------------------------------------------------------------------------------------------------------2----------------------------------1-------------------------------------------------1--------------------------------------------------------- -----1W-11--------1----------------------------------------------------------------------------11--------1----b******pRXfn*n**X*f***B***Sjfh*Wv*hU*miW*NP*W*yszFQaGalI6oK9*96f4--------------------1--- * b.121.5.3 Densovirinae-like VP
[ 283] --------111111--1-1-1---83441155123111233325537754998--1--1--11-2-76 1566P-12111222YQLDD-DP33NTEEEEEITTXTMOQY3T9VBF2424226A7321--89A1H7OIPN7122222312428-1--14553-422---1313495632---------------1--22---13-544771-165B64455333222222224211AA62221222222212427----112355555355356464613321345422152222111118311111112111111-31111-312332-21233-1331-112-3332231111-------1------1211111111112122---1111-44556754565-3-2355----71311-3-2-361112--11----1524-383351311223B78544A756543444442444-77B77C8A7E718775CB6CBB77643453C6434565511111111411145381111111111---------------1-1125714136664789A987545575AA656637A876A8622444653567495822663235621121222--134446844242234313-897252833A97A4C434233333433313111111133-13463325466372125444422322312223141-1-112------22542232222222222-22222222222222222223434323333333434333333335222222221322222222222111-11221232211925333122323223213313321322231678755665565523331--------3222222222533454344554354211111-2332122--------1-------------1-------------2-----2---2423 111-215-5121558B9CC9ACACBFD6757777887868897878B9BFCEDDA8B96A676585573564555F56556444662338BA97B95555366444-2H794563635433453852436Q4157B2545323352425452-42423363444244927553533854X45389CAKLAB6B337525 * b.45.1.1 PNP-oxidase like
[ 284] 21-1-14334544463--23311231112122----1-----------13221----1--11112-11 3264C31233223154487-83337788999555558AGB286567423221554413--546276C5874--------1--61-11111---2-----1212142412---------------3322122122255544---23241344-1222221232214321332422111122213-222--1-12444444643454445331122445343321-------34-----------------------123-1---11--11---11--1----------------------------------------------5-132323343312-112222221---1--2-561131--21--1-11-212733211111438772245753533233333235-56754D693761544646A456A97431144645565573333333342242327---------------------1-------11B722665667889887555555E8555646BAD8C99254354473397947A446322145333334443294628534344563554-354131222445475232--112211212222222223211334322442414122333322333342324433---6333------32112324323433444-344333444434344444223221342222222222222222232232222--233333333333---2-1112455552446222211-222222212222222334335575474434455243342313411211115222222222244322222232121113-333344--------1----------------------------11---21--2211 ----763-743-233HFkYbQTKjYdVCCBAC9FEGCGGFDEE789TJKUWeutXQQaCFEE345453344444544145344464232FSDFIGC3334377544-6Q9L86776543313548C265CZ71639242253572354537226475687C636983836276873643i53386GIEvbag43ABBI4 * d.145.1.1 FAD-linked oxidases, N-terminal domain
[ 285] 44-3-675766666642768787B74453653965442435467736729CCA112-11244666-11 2796B22222223244455-573358555554788857DA567235243112244622--444466A79632222222-17672232244443633---2934254725111111111111111BDD9BB89A8A55599KBF864596556344443433346344454131-22232-216645532245444444434344443474334544356445322121214423333333333333333333----11---------111---1-111--------------------------------------------243287777676364554423245121-521D8NNCFC334HB2223--13B4444211111565643346355444324232331-6545665644313332433443536533326654555442222222274434847112111111111111111111111111113233413434766656597666997A888958676776747456A459995857786984657633333333249AA1MXDCGMHDGEFFF-JDI5GAF65DD8C59DS53452665552434444334346635465325253645688985976779866A995--1789B------64546718886877788-89798768788878888876665533587788888887888884767555711444444444444111311111233383564222213222214222333333333353667775556666673334222232223577977777575895334244222222243B-223322---------1--------------------------15522313333522 22--112-411212222111111211211121122221212112112212222211211111111112112112211-11111111111211211111113-121212411243211111112111-31161-11211111111-11111121111211-2313123411211311322c2223233A81472236231 * a.1.2.1 Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
[ 286] 33312-888888998A--22111-2---1---------------1--1--4----------1----11 3FD25-1-111---11111-13--571111144555137A342421---11-2121----11C-44D655------111-2-53-24---1-----1---113AB-8----------2-------1-1-111-5-899893235C-3434412311-------22-6365------------B774179168122222212-11111214---12111534224------87--------------------2---11----1-----------------------1----1---------------------1---1111-8L7AH89898BA7A955665122B3732458C9HFAJII4HED87793--F565443111--36PST6358A8F81211-11-111-KIPHJNJN8D41733622A8728FC635-BA1454488966666666C4431KB3------------------------------3782-8B968EIIIHE52221IIJF222213C8JJHJ7-5BBAB7934I28CF266B3493C4--------117AL6BJ8E7HD6LLFGF1DIFBGDE8D4444B77B6-------------------322--22GA2CAA63B579EBCCBC7BAA6B9667II---1255-------1--21-3332322232-3333322323324332331221-------------1--1-1--81--1112--113123312222---4--------121D46---------------1112114-2186BACB47E9BA7A76534---------452478998865ADE33565663331111--G55544331--11111531------------------1------BG4EF7AA9A27-- ---1321-711-22-323221312322333333432132231233324131534122122322-12-1-1-112-1-1-2-111--2-12522216-11-143312-389I36559P85544A4CH475Ei8-76D2533924B435744F52F4825A4AO2D85EFCECN5C6-23-D1--33BCEF2I94353132 * d.133.1.1 Molybdenum cofactor-binding domain
[ 287] ---1111--------3----1---1--54-113-1---2111-2L-1221C81-1--A1-5-1---I5 6Je15111111--124444-45--75444442955523A7293C531-1---223312--143-645329---------------3--WTQ7-H-----17-42EH82A-----------------3141---5-48858--182146549113--1122--231B59C8-1-----1----43413411--2-----------------11-1-12-111--1----1-41--------------------------1----------------111-----111-------1-1-2--------------1---------41115232424614-1-22----415----11--132-3--41---2---71E2--1-----338342--22-32----------1-32223142321-1---2-1111-----141-211113--22222222-551-11-------------------------------1--1--111-6344451333366673344-4659-11-1---23-1--2-2423--624111--------1-3-1179-73----12----7D634AG1-4447Fb2D--11-1111-1---------1---211---312-15---21-1-2-----11-2-22---31-2------1--1--------------1----1--1---------------1-----1---1---1111-----11----111111111112---2---------2-4-----1---------------------4166664443334423324---------1---1----------5323433323------139978ED11121222421------------------1------43344233232I12 -121526-2273--2334-1421522---------1-212112-22111213452232----1--1--1-111--22-112---11311--2313411---1----14***IIKTIJCDBABGCkRDMFe*P7SFfEG8DKCIRC9GDDDPDDQGTILNFGIlnQDFODASDzk86764C2334579BH-DC5288477 * b.68.9.1 NHL repeat
[ 288] 11111111111111111111111253325334123111111118633624B8611111111---113- 17B1J2-2221----2234-37--3422222272233864271EA64231213-3-1-111291D46ROH5-111211224151-1311121122211116325F3534122222211111111212321331327864411282847F44412332231134343EBJ212212212112212112111111111111221112212122221112211331222322213122222212212222322112213433132322113332132-1111112222211122223112212222222212222113222111122322111211111321222433412131222122321311121122211822D995111122158B5548737722222222224-6797649724615555524783341424334433433545555555523332B5411111111111511111111111112112-535352232387668866455773B55653589946561-333DC745869773647323232222443222544D472523H42J3BB71426C6473644547A333--1--------1-----------1113332333376736466345645343464542-2222621122224223222222222222-221222222222212222233333322222222222232222362222222312222222222221142222222222557232222222223222222223223242246585578437445335222222222245333444545335534343544551111-19133467611111111211-------------------------11211111112C11 3414696-C44465A867756767776665666656599979965657667777445765554545555466544553555455644335766645565678557536IAEECAADHA978BC9EKBI6**D1TEOBA87F79EA99A98A67K8EA9D7DK5CAI1335CA8856467c45556V8EFACC7685436 * d.122.1.2 DNA gyrase/MutL, N-terminal domain
[ 289] ---------------------111--------11----1122--51-4--735-1-1111-------- 1---1-------2-1-----------------------3--211-------------2--11---------22223222------2--5573-555---111--2-6-1-------------------11111-111112---2--11-1-3-1------------2411-------------------1------------------1---------------222222---222222222222221111-14242241547222222211-1221111111111121111111111122333333333331111111111---11----------12---------22-13--11---1--------11---2------------11-------2----------------------------------1----1--1-1-11-1------------111----------------------------------1--------------------1------1-----------------1----1--1-------------------431---1--1-----1--3-1-11----11-3--------------1--------1------1------1----------------------------------11----------------------------------1----1------------------------------------------------2222--------1------------------------------1------322--------------------------1111-3321111----221111111-1----1-------131-13-----12--1----1--1------2-- IE46SWK-*cUT23344336222456633233323212111114445656558H577555554411--1-2121212221123322---1444A3F2212342333-In**f*hj*rQQLMPXOumKpP**j4kZ*MNONdSQWVHQPNLTNGsUYZasFSVSpe*MePPSnqpL-OOG*CCBK8Do*y7tnBHYVXVo * d.3.1.1 Papain-like
[ 290] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3----------------1---9--------1------1--------------------------------------------------5----------------------------------------------------------------------4----------------6------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------3-----------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AB-111h-C-12--3--------------------1------------------------1----------------------------------------------58C*******mlefq*h**c*t***2***Yqeq*p***PwpZW*cM*n*yuuBIhBMRA-F24O7AMM28-4L29443123--2--119129 * g.24.1.1 TNF receptor-like
[ 291] 11--222-2222223311213-2222231111232-5113112-3-1213325-3131312521-2-1 3-32335333453231132-31--2133233122223121-63313431221132121--343-2243B36-222-1---21-41413224413431--2623166311-1111111--------13143227212444311-32333532323123-32312313684312---221--112311-12-12222222123821221141114-2345122122211-3342-4446444345543435654232-11-12222245123221-223222233433222223222232233223223333331331113233131442223323122312246663352-223225461-1-2--221--213143223--1--21241312221311111111111--21313433132-3226223244232525223232344322222222234535342------------211-1131121111-1--41-422222122212323333222542363343212211232246233-214241272-4441232334333-315423543341-1324-2-333434223435533411-1-1--1-2-3122213121-3436553716544423323763444412457251-122-311111112142322354213124-222121313221111211312234342212211222122232121122122315333334333332-21111-122222233A3421221123212122232213---334654-453432345347411112111-475655535573323113232433-----21-22--11111-1--13-12123---2---11-----121-11-3123-3-3131-33 GE88FBS2VB89689367669546474655546667234464398968769ACA75567BA75568581457424943666652453427A369795568682C7A17RGSGQCPHEG8ABIH8FLIPCW*G3KCTCGCCLFBDEEEBADSDDKAM88EITTBIIKGCCDxIBLD2DCC*BBG89RADO5GPAD8DEAA * c.37.1.14 RNA helicase
[ 292] -----------------------311111-11-----------1--1--------------------- --------------1------------11-1-------------------------------------------------------------------------1-------------------------------------------1----------------------------------------------------------------------------------1----------------------------------------------2-----------------------------------------------1--------------------1-------------------------------------------------------------------------------1-------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1---11--1----1---------------------------------------1------------------------------------------------------------------------------------1--------------------------------------------------------- 1-1111------134TRPIyxmdm*luOOGNCIMIGKNIKEHH9EDNKj*zk*ubhPLLLKPDHUFGG6JFKWJTLNHQOGLRTIU5AA5ICR8MJQILG75MCI9125B*DCBBYHQKSKC7B*XRyP**j3kXmjNLMNBNYAINJ97eKQ*IBHVN9CK58M44B8D635E21111-----16ALGKC4-22212- * g.80.1.1 AN1-like Zinc finger
[ 293] 55324622222233435333433122225232111111111111111111321122253332112-11 333-422222112122244-6122334444433323324526431223122221131311343232257411111111321122121144441344---4425352254232222323333331111211121212223311142523422311113222112222323711112121111233244222333555454754555565453333666534434333343353244444444444444222324522332122312222322111133355543335455445545444455555555566455655555553444242222222526433336745332452432222222112233443323241222-----225555223224222222222223-45535544551-4333344334432322334333333332222222214412222-----------------------------122221222114554445444344445555155443433-144422222223242111211132111111123312142434232245222-334434463343335143222422222232333333322332338623112134335465338433548B55C61-2211122-22264445546445655544-44655554554543464454545533455555655565656556344444421454555535555111-222222222212223333333333334432222224211432222212122222322254555555415766555555746622111111111111--2433333353312211232----2-212232122222212123335433454531412 22--325-E3573545943aLYDdecTEDCE8B7443444365B9963YvJOWs99LQ573823223315224112222322222333468394341211363332-459FDKEGG79559566HH8A6Y*C1D8B6956C44B635663A67E8776E27A9BE36S6587886333161113175BC56423A6842 * c.56.2.1 Purine and uridine phosphorylases
[ 294] 33111-311111111233222112422222511-111123221212111212-233343333232-33 328261122221-4321----41136-----3322211A72524322-1-11675121--223345856721111222--42422333555526441--4525633534111111111111111--1211--12133344111232422442222211111123224442111111211112432333322334444444444444444455434444553723222233342444544644444449666721431135-1-331112-422861213221----11-----------1----11-111-12111111111462562222222133124432225331143351561111331398531444138336-1--166CCC2357978544554452547-7797685CH851EFF7888AAABDA945254888888572222222267731343-----------------------------24564368648899A986333388GC77676798F8BC91376477887C5F3B822111--22--11111343-2224331--23113321232232449333323242433333333322222222231432225674544334444565344555455454532-12434------56645435556575645-55567655555755555557B956445555555555555555596644445225666666666661133222223332154972223341332332224454446333C488888ADD7A9C94A99223222222234456666665566113323333411-12224333344--------11-----------1------1-------41233242222125 12--464-831-3335A777788EBA59988988785CAB99C768757ECBHF57A87989F564442325434464566775793347D6A785A797525885-3A5D7434542222543451734P3-3652642944562434253144614632B57834A35938B526A3G22258ABLL8A453DDAM4 * c.91.1.1 PEP carboxykinase C-terminal domain
[ 295] ------5353353553-1----1163354115--1---------2-12--212-11111111-2--33 49F2D325776122GF766-6L11HE666668PGKGHGbY1B6B7D37-23-DBD47A--BCC258DMKF41---11-2-219--1--32431311----52636-834----------111111-23131111145566---8EG56464535332234224428679411222112-1116852411-62198B8A9AA7AA77887743148A8356655411--1-A61221211111112111--232---22-1-----111--1-1222553333111131112-21221211----1-4-----51-12----4241112223322-1222------31--1211--43211--221212111-6-6AA98-----67TEE432A38A357485576469-45664559EDD-NCCDEDJLJHDE99A8749B65886991111111137732451-----------------------------16Ja6199788HGHFEFC5566EEMH988949NDRCLBE11BB8CC474DBA1BA153122261-1122221223GC4211-2-1-4-----1221212233453A9311--------1--1-----------12264261394E7246454657433274571AA---4312-------15324-----------------1-------------7652112-1-111111111111114-----------------------17-----355512556---1----------14444434122B1B98A8578598A76634111-11111-444444424685556745656565----1-2-441111----------2-------------------------11211-1----213 12--855-71--23A47A6A78887786555443546A78A99443325B68DG53647443234111113143422222133453111-1-75111--1112134-1B5E676465527685465-647O5-65D46656488A564335715258579C76A764433356455B44M46595G5AF497A835219 * d.32.1.3 Extradiol dioxygenases
[ 296] 22-1--2134343231-122211-2111-111---11111111-----------11-1112222--11 3384931111123142333-321146323332545466B865584565433195944622776496C99742---211422271112133432211223455657675744444444445555322122212263566441133513211122211111111121433323121221211215434422162566666566467666667666566468744546656455534444444444444445554232-22-31124533211312224433432233133433333434342222222222222322222333432228222232223433221111212115222111221221123232334631633444434447674335545677776676678-334336336733555245B664984A5346485566546444444445652255433333333331122222222222223333347F6433233766475644444468444436436566433444653334376643253122242222222233355313221112232211565366643333345-4121211111211111111112122244448333453354533344433334333345212542322222253433553335355533-3333354333353333335687434535444444444444444422233333234343444443422244444444443254322233222222222344444233327355553555354652342222222222134443333355455553333333322221141443344--------11211112-2-2322222222322211112212131213435 45--655-F54144434545553554633333333333333333433345457544333333324222232234322122222232232454444632444225452696BCE99885586787FD6A7T*92BBI7866A57B537777944E667896CN5775AQ96Y65968455*5744598JB48A5697675 * c.36.1.7 Branched-chain alpha-keto acid dehydrogenase Pyr module
[ 297] 112-2322222222222234433122211122--2112111111121122111121233311112--1 1461612244411222211-11112311111-33332433141421312111233111--32224145776111112111932112111122-111---1344473341---------------4111122112257779111529377776353322232236238785121111131111222--2212333333333333333331322123332224221------25--------------------112-22-11112211221-1111221111111121122222222222122211111111132211-2221233221111122131321111116131-433-1441--4222---11113315411322222327673333333333333333334-554454447532744466655644353334554444454--------222--3323333333322333333333333333323324444-35544777676333334444565435845454522776344448454644354343531111111333334273244533443332332232362443483252221211111112111111112112333344455333776666666666686686653-4333422-22234353334446476654-444655656546644444633333335434344444445443434445544323555455554442234111113533535332223432222233331111111111338888875664444355532222322233334333335455356555554443333223144545522222222523----------1---------1----3333333333-622 3322B98-C53-565555555545445545555555555545555545465555455555554442222421444222222555453335845536333332377C-7A9ONWEEQC99688C8KT6MA**C-HDQA877E9BDC7B966B88GAD99FADHGECA7R8CFEJEB3475*33359GEQQ5N68987799 * d.43.2.1 Band 7/SPFH domain
[ 298] 334221----------3-432322-2222123------------311F12422--2-3351--1--42 --5-811122211135555-5533445455533435317333132813-541637522--ED51M6AFAH1--------12132-1--1231-2-----1522483653---------------1--1---11714778A-1-F3365222811---111-221-58778----1--4----N8A24--1-2666666867495596859AA776873335854557675952--1111111---11--1---111231---11---11----1--1-22342233--222211132313333333343333144--212123414B1212412B1736223675D32-153332--2213441432325242-22111-----2-23211-22232------------211-13-132---11211152132232114-41211112--------1---2---------------------------------1312-2111-3222233111111143222-21213224--335413---31--21222---1--11111111431-F-4------111---1321535--1222AA-41--2-112-------------------1--3237242-E5585A43C9B2B85623C--32111-------2-1--1----------------1--------------1-21132-----1----------3---------2-------------2D-----11112-411111---3----112-2222211---11233232513333313331--------1-1-21111133111458999A88B3333----11---------------------2--1-6-113-1--11--33-22111--1-2-5 4213897-823235C8ADA45747747666789EHFIHGHGII45554KfTOYULHQI9679G44334245445534264555555444434AC2533334G3NUQ27VMsIBCHEDA8969BIHH7GAQ*I1JHR7979E8AB769787B85E9GABD5CFINB9BH76S8CH7-DS5Q232NDLud*9x*G78E8AI * c.41.1.1 Subtilases
[ 299] -------------------------------------------------------------------1 -23-2121111--112111-11111211111111111321-323---5111-1--1-----11---24231-----------------------------4122422-4--------------1---------1-----------6-15--12111444222351-342413231-221231-----------11111111-111111------111---1---------21---------------------1-------------------------------------------------------------------------------------------------------------------------4454-----13323---1111-11111111112---2111-1152-111-2111332211437111----211222222221111--1---------------11--1-----------4253-222223444443555344545555-58373335-13331423242315-22-132221--------2--2-2---------1-------------111142-2-------------------------2111-434433333355535343343433333------2------1111-112222222222-2222222222222222222222112-11111111111-1111122222222--1--------------4-----111112812---------------2222222223313333253222422222211111111111--2222222312222545431111111--1-11-----------------------------------------------------1 1144DDI-H98-BBEBBF8A89CBC9D564555987A99A99979ACCBB96F898C99BAB433323121133211--1222222232976BFEF688A8E4886-6*woXVQVWLKJLHKPKcSIdL**X2bQiHKIIZHNRIEMHEDSFEdKRNJPEKYDPQL6eAANAJhE1PUR*OUSMEHNPUEWKdtORNXs * b.82.2.10 AlkB-like
[ 300] -------------------------------------------------------------------- 4-1-O432112523QNI77-7522vI7777798666ok**-GGC1--2-3--245112--PE12fFRPGn5-----------------11----------E---g---1-------------------2--------------p-9BE-EFH--------------KDj2-------2-----------1--V224249293375AE4--99GJ33I1--82--------n1-22222222222222-22--------------5------------------3--75--------------------------------------6----9-----T-AA----2-22------323--2-----------1-2---------466-U---2A---------------3333313232--4AAF11-1-1G-18-2---4-----22---------3-----2----------------------------------------78979GXDIJC4468hhhbFS5558-6-----D--71-A---83-------9----------7----------241------------------*J-----------------------------33---2----------C--------------------------F1H3212111C1CC411-1121114144144111111114I6kt3111111111111111131111111--365666333363----12122111125Q-D---------------32343-2---FAKMGJgQRT7CDEB1XK*-------------6-11112--111141111----------------------------------------------------------------C-- --1---1-11--43EIEOAXOfXnuki889AA8YdVHEDEBDD466D9k*TNLNEAOaN444111111-11111111-11111111123644E1521111126111-1533--------1-----1--------------------------------21131721---135421--12A434112113X-12126239 * a.28.1.2 Peptidyl carrier domain
[ 301] 11-1-1-122222222-133121132231132---1111111124225314532211111111121-- 3392E212--1131A5533-38--5A3333338666D8C7-5487222111-535332--643391EJDD3----2211111211222434415111---2166F3649---------------11111111--12223311151955356---12--22-1-1272452------------1122---13-3998988963988688616434685221344521111194422222232222222422341231211111122222112--2--1--1-1---31111111111111-------------211111111--3-6544444442421311-2322212-1111---1---12-2111-1213-4B777-----537971-34316-33443442446-BA79A77D8F5-8CC8A6BIGAADA4-33469524459C222222225634422511111111------11---------1111-1-31-26546JQQRQLECDDBIIQPFFFF4GTIO7EA4-278713821633694191121282-------3-414243112342344225-54512251323434A3633222111111-1-------1111143432457A48323455432464456456547--21113------37874834664444554-64454354546553444447A6567535444444444444445734344444-433333332333---4-1--12222-4EA8---1-1--------1556772514441DDCDCINLFFGEG8B8A13322332312228343245524565474762441111--224433651111111111311112-1-12121111112211--1-1--------2311 1111442-531132443CC49CD68556546456673444443645665DAAHE77886544214-2113211113411211113266736438DA22231-1322-2G887F73A8444235394183Jk6-85G3322733641331-42353664756238532221722843642R222359DKJ8KA43E7543 * c.23.16.2 DJ-1/PfpI
[ 302] 11----1--A94---4--------5UP23-4------------1---G3-MGB----------2---- 1121-41A--1----------3---6------5-----B5-17Q--------1-------13--1-3D1-------------211111118411B111111111A11111111111111111121117661271113341---6-k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dLQc31F111211112111121111118292112113111111111121111112411113FE112121111711111111111111111C11*11111*119B11AC166***111111S111KJ111111111111211111-21121213991n111611123211111111111 11--11112-3-11-1211111111121111111112222223211221111121111-121113211111111212-211222112211312111-1--1111311222498AM35624455659355GX71C4C41343354536444D32568342--E25443523M91242122E2222213331321121111 * c.55.3.4 Transposase inhibitor (Tn5 transposase)
[ 303] DC317BGGSQQQNPQPF3FD664P868A7GA4233373323329236J325344IEANd963337352 D8F352-11112--123fe-f51113gcgeg-3434311134B543161121121--1--32222223131----211116213173-2211-2122-----3--1E7211111111111111211K349-2G111677A---41DOFKCGk2378612321NK1UBLI1111121112112135DB121822222222222232233222222322322212211111122111111111111111111111-1-11-1--1111111121---111--------1------------------------1----------72211222322212111222222-12111-32G3493G8437I23582-11A2J33-11--1451545328EC8922112122228-371324B3554-C4489DIHF86I57--222642112126666666635851155------------44A915635-34------1155-1221299AACA51111775222112297776A61423575632BC635D22D311111121-111H32H23132D-171-51111-282722M111111242521-------11-3-------21-32EE13252-121111311112111111111111--2B36C------1-11--1-------11-----212-2-1--------12232-3412--21-11-11222214---1-----2--------1-1--8133232121121121444----222123--------1---4211322115211122754---------1---1111111111222716112224131--33AA7775--------B---------------------------251112211115-- 11222341532155552433344433333233343232222223344333444424353343454544345454544444444454445554254555545C36632444AC969988467686A97A4Bo84A7A5765635B557567763F459697554679667684D753335G3436673354651232222 * c.120.1.1 PIN domain
[ 304] 22656642444444446466464E444424444424444444466466242-25AAAAAAA444A-66 24647514333--122233-3333273333323555559D466536354332553544--54B264BA86A2222222----4444444441-423-222222222242222222222222225444444444454445423-45224322322--------32324422------------22233--24222222222222222222233222222225222------32233333333333333322222----------------------------------------------------------------------34-1-------2-2-2---1-1--11-2--236612B--355-------26242242222223E6B42C4486822222222222-88A669666842422232664446482224442222849--------422-4844222222222222222322222222222222242224KCCI64444464444448B44442444E4KGF2432278468C5468A2364222462333333446C442QOC44B7-6A8841868372A24226244K8--222223221--111111144664225422422224444445444444444444442222544------74444546669699966-66667996666966758775565444554445455555555454445444542444444444444222222222222262464222222-222122222222224222246666242224442222222222222224444444444444444444444442222227-442222--------1---------------------------2---2-2---4322 54--555-B327444666567777775665666666766646666658768758446666664222221222233221222212232444746544444447654O-546CBG8B895555776DC5D4Jz91A4B46449558945665765C4857C8CL56556C5BA99766442T22234A6DN6A64556555 * c.23.4.1 Succinyl-CoA synthetase domains
[ 305] -------------------------------------------------------------------- ---------------------------------------1---------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------1--1-------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------- ----99G-----224-------------1--1-----------------1----11------1--------------------------------------------L13p******ojgcloj**e*i***F***Zogh*ct*lZohlW*cV*l*txrPi*bSQROvGOeMZVL-11181111131-2-33--11112 * a.11.2.1 Second domain of FERM
[ 306] 1111111111111111111211114223324231122111111222121111111111111---1122 1232745555555646644-45336644444558785544243634232332333233--555274444542111222--1-3213223324-2--1--12322533521111111111111112334344333433333---3166767755555323343556544643333433333332111111121211111121111111211111111111121211111113112232222222222122232111-11-1---11111111111-21111111111111111111111111111111211111221112221----1----------1-------------1--2--3-----------2--3235554122235565765456555777777677771666767664762AAA89AB99ABB5644345787885544444444466644555111111111111223322222222211113555444444434434342222223522222233333552222244222232442224332343333333334444311-2-3333332241232322222432365234222233333213111111122333444444334446244444444444444544332-3443611122233753333323333333-3323333333333333333555545433333333333333333433333333243333333333322323333311113254853334433332333333333332325333334343344445455111111111333353333333333333333333322222223555566111-----1----------------------1---1-3111122113411 --21853-A4626555568465676675443344433333333643548797A8676768A842322452642327445443333424236354744663434545-5P5HHNLKDE889A8B9GG7H6j*91IBL799AE8CB8887A9DAAJAIGBH7C58B6BAB87H5988BAAD*DEC9ATELT9GFDF84669 * e.7.1.1 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
[ 307] ---------------1-------------1----------------2-1--11-------------33 3773433333333344544-44335544444544444445366334343333434333334436667444333333333333543444333333331--3333344444--------------2333333333346336633654333366333333333333333663333333333333345434--3344444444744444444444444444444444444444433444444444444444444443333333333333333333333333536333333363333333333333336333333333333333333373363333333363639933333334343343336333474474433334333333333333-4333333633333333333333-33333333363333333333333333433333333334333333333333333363363333333---3----3---213333333333333333444444333334433444434433333333443333333534334334334333333333337333393333333333333774333433445554433333343344333333333363367443333333333333333333333333333333-333663--33333333333336333633-333333633336333333333333333343333333333333334443333333333333333333333444443333733333333333333333333333333343333333333333333333333433333333333333333333333333333333333333333333333333333336---33-333333333333333333333433333334433 3333334-C6R34433333433363623333333333323313344313333332333333333333333663333665633333333333334453334354438-3589NcHHHQ47D8797B76B6Q*8-B8H5847B858576875848C87977-9R34654T647ILC33333*64333E8EO4GC169334F * d.130.1.1 S-adenosylmethionine synthetase
[ 308] 222-212232221321111111-51113223132522354454343352568526925CAB---2-22 3831412323313264322-241124222222665644651546233-14413341232223122263431-11111132543111-1667717332--2411254322----------1111233235433334344242212166874424544222723543978722522222522211122233312244444444244444423431244411122111111212422222222222222222222311-11-3212222211112112133---1111111111111111111111111111111112111111-48A675555555656454437887532331141777422376333545223434334-----446456227659735443344444-4454536622413553222375343542352252353212222222234443958111-----111-1211-11-1111232111425434544744444545555557566662634477651256443576435373444733544222222224484435B548794449972C8DAAB8A7878757682321233332332222332223213114344243534164444233454445434441-12215------44443424444444444-444454344444444444454433324455555555556565544344443313333333333331113-----2233245334444343333313433334336455837677755547887555513333323331112333333414455545445552333--4833333311111111211---------1-2-1111-1-1111164345757672333 --11-32-1-3-1-6-3-1325622335421111212---121332121351374533322323--2311--211---12111--11123B63755212312-2331-15GEE66E754976G5TX2Q6G*C1AEI5634L74UG3D385F*4I3548B898577B496J666C44253B23356624A2771225221 * a.25.1.1 Ferritin
[ 309] 21-1--1111111111-111111111111111121111111111111111111111-121-1111-11 1121222222222222211-1211321111122121223212221222222122222211222222223232222222211211211111211111-11112212312221111111111111111121111211122111111121111111111111112111111111111111211111111111-111222222221222222111111222111111111111111111111111111111114112------1---11-------11-1211111111111122121212111111111111111111111111111311111111111111111111111-11111122112212111211-11114111111111212222222221111111111111-11111211111-1111111111111111111111111211111111111111112-----------8-----------------1111112222232222232222222222222222222221223222222222222222222222443323322222212512311111221-32312121211112222111111111221112111112111211332222232233333332333333234344112232312111133323343333333333-3333333333333233332344333333233333333333333333233332-2222222122221122111111111233122222221221122222222222222122233222222222232222222212233344322323434432442442223333112111111111111111211----------------1----------1--1-1111211 8846B58-YEC4A6E55678B9A96ACBB99999A97878578AA97993B9A8AAA7796688767638A78A588378877877AA9AD85A88CAAA8A94694CI2hNRLPHKCF9ALGGkZ8dC**J4ZRYD7CBMFBGG8FFCEKBARBEGEKJXZkGCGDXOMyGPJE78CD*FCD9DCCFN9LE79AEGB6 * d.258.1.1 Chorismate synthase, AroC
[ 310] -----1-----------------35475344411122222222443443332213333333-337211 1111111111111111111-11111111111111111111111211111111111111112111111221112221111111111111222112111--1111111111---------------11111112111222114441111111111122111111111111111111111111111111111111112122121122211211111111111121111111111111111111111111-11111111111111111111112111111111111-1111122222222222111111111111111111111111111111111111111111111121111121111111111111111111412-111111111112111111112111111111111-11111111121133322222222311111111111111111111111111112-11111111111111111111111111111111111111111111111111111111111111221111112111111211112111111111111111111111111111311111111111111212112111112111111111111111111111111112221112112111111111311222111111121-1111111111111111111111111111-11111111111111111112121111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111112111111111111111--1111111111111111111----1-1111111111-11111---11111111111111 66337774RYD89874855786775785645555655545455555557776A8566365554335444445444453453333334557B788785444554AAC35WWfTXYUUFGILNMMYQVGyK**P-iUyHIIHYJKbQ9GIPGREBYIUFMTGHpEc*DEIEGmEIbF8BCA*99958bIWc5Q*78EDHDH * c.32.1.1 Tubulin, GTPase domain
[ 311] ---1-1-222222221-2211231122121-122111122222211131222222231221-111-11 A9A2212222321222233-32112233333222222222232322224112223221115321223232211112222122274576BCA81D32---4F588E8B39--------------263466443563322322212295553314433133221252758A6232211121211233115422224444444454554352222334544233222222221C511111111111111131111111132121212233331212111111111111211222222322322222222222222211111111149536222222232333333223112112215268844223452313131437B344-11-198K7A529GAAB734673745658-ADB9B9CB3D7-B998AABAC6BB7A2444245556314666666667CC348991111111111--21-1222212222----13363433211CABBCC76555DDAE778774A5C6BDA136591333467355236546854444225225493751743445337A44416757596663333955834453333233111111111465346565567679875CBDDB6AEEEBCB9DFEF81-27436------55341835996567565-7555655565766555553A9A4786554534455565454356443546521677777766777--235555668677675922124432222-2137776736435668997787929685477B234332333589BD566668BADB87858557673222226-662222-1111111311----1-1-2--------1-1-------121212225534 11--212-1--132211112121211211211111121111111-111212212111121111111-1-1--21111111111111-1-21211111111121111-23254566C3121235466444IV5-A3742333-441131233-2325123239344-1612412441323H2221122551532252226 * d.41.2.1 NadC N-terminal domain-like
[ 312] ------1-11-11111-------11115-A1---222------BX11P12baB----2-----11--- 112-1----------------------------111-------1--1-1---------------11-112---------------1--1151-------19522QA436------------------------1-----1---2---------1-----------------------------1--------------------1----1-----1---------75721-2-------------------------------11----------1--------------------------------------------------------1112-4----1311-1--1--111111-1----------1--1-------------------------------------------------------------------------------------------------------------------------1---------------------1---------------1------------------------------------3-------------1--------1---31-1------------------------1-----1-41-21-1-11-2--32--12-4--2---1----------3----------------------------------1111------11-111--1--1----------------------------1---------2-3----------------------------1--------1---------------------------11--1---------------------------------1---------------------------1-12------8-1 ------1------1-----1---------------------------------1---------------------------------------1-------------2-1py*m**rcefeV*h**i*k***9***XwlS*gi*hTpsfQ*TO*e*YgiFMOUJIDNWJJSJaHA--------1--------------- * b.1.3.1 PKD domain
[ 313] 221-1113111111111212111-322322221---------111--1--221-3112111-1-2111 143-11112221-1-------1--------------11----1111--211-121-11-2-21--1-----1------2-1-2--1--2223-4332--3222162121111111111311112---2--1--114443521-823211332--443322221322343322222132223264533--2433878787986899788644433889545543434343394422322223233222233323121351111122113432123334422232123112222222222223332222232222331113332133-3-------2-21411222241134412213512-222-132312422-42223111-2323423223323222222222223-44345343242122242322232323232343433334322222222355333322211111111121111112-1-1111111-5-12-111112222222122122323333132222112112212211131131122121115211111111121212---1-1--11----1211121-15555A4-22121111111112111111112211116423133234269778856777478684651-33111------33222442222222222-2222222222222222222333223213522222222223222722222221132222232222211131111122221332222211111111111122232221121211111232122222322212122221135633333344455554444435522221111222222111111113152132--11131-211111111122243233121211532 34--524-YGGA54BAK6648798B95565454666764636756823485C8944332833433643233353482365344243323AB4KA69674358445C-7A7lDGGHHUA889FPDiYCZE**O4ZNh7F89NBCSIBHIBEMC9UAOHDIDKN7EILFJHJO89J757N5s56796F6CF9EKA9D68A7 * d.92.1.5 Neurolysin-like
[ 314] -------------------------------------------------------------------- 79D11------------11-1---1-111111-----11114233--11----1------1-1121-11141-----------41322GGJ8-B661--AHD8BHSE5D11111111111111133556333643---------1411--1112----1-1-1--22125-1-----1----1-1----6112223234333334333112212333112121122222221111111111111111---112---------------------------------------------------------------------14133222222221213222333112--121112212111113211116863277772111147CDA6758999B55555554556-76A66A795A638667797A9866665A78A8BABC8AA44444444A7777DBA1111111111111111111111111111117576458858LGGFHJDCDDDFFIGGGGG8FJCD9CB824868DA8978987G389FA6588523111114467AN88E377D639D9894FAI9BAA6C78B7HX84955434444452322222223543444CC37BDA5976CC9B99CEDABBAAGBB9B1-56A5811-11167434555777577786-775676666777656555577643753474555455455555574346666227B9ABBA9ACBA112633333766655H7A4443443222134335677656698BAEEFEFDEHIFFGHFBCC3333333339DDHF77777KKECC8898A8789944441246DD99A92222222263--------------------------1-121111114227 -1-------------111-111111111111-111-11111111111111112111111111112111-12112122-211-121211112212121---1-1-1---3------------------1--------------1---------------1--1-1-1-------3--------2-----11----4---5 * d.79.7.1 OmpA-like
[ 315] --------1231112----12-2------1--4---111--126-41612B76-5111121-11---1 397-7-1--1---112311-11--2111111131212523--2111---1111331-1--12112-1257-1------1---4547A4FDE81B4441-9D488G784721222212222222C3-3432-22A2811A6---A295767555534311322242587AE13121313121122-221-21-6A8B8BBBA58877996554379A8-1241112112-247--------------------111-11-11-1113321211------1-1----------------------------------------1-4-748887868785-63244144561-11-3--124-3353----1-7D364-3342121212543-2-33332----------1--1312111213-1---1-211221252314-35344353--------1211-1-1-----11-1-642146138111331---232452-2213612211322222223322223133-234421-1233-442-4114251-3312111234313354436A73414415A427269967582554E6CK21221222232211-32342432164-113412474454435455237533296752A7---4453------1-342121221111111-2211211111211111111--122143121221111122-221212121133-5333331331311121-1---222212A233333312----333---11--1--2233543444365364411331111211143656444445418824413112232222122I7966554642754482--------------------------11444121212734 6--1439-D88478A3-34559-527732444756732311312212337814534472111463254264112386464233--5676158-63F2111214A78-4LB*GLKIOODF9DAD7MKDTDg*I6LKWABFAGBANFBC9EDJD9cLMHFM7C59DB87ACDC96Mg1EC6T596349A9F2BB636779C * d.157.1.13 Alkylsulfatase-like
[ 316] 1112111-1111----11---1-211111-11-8-11-1331211232112211113--112--1-1- 377-6112---11147744-671169434545787859EB168695755533946443--556294G7893111111111613-112-21-2-------26-13111731-------1111112--2111-1-1-54444---2522332211222--------1223323-1-213-4--112211-11-1-12122121111122132---11121-12-1112-2--34-111-11-1111111-232111111111111----11111-1-1111111111-11---1----------------1----23111122-22154AA958A9497-2326253352143231133311132111121-449-33444-----1-432-1-41-31111-11121-2-221121-5232-322412344375451773532322349--------2333-151---1-222----1-35--1-11---1---352F62154218678673222333554554128347787--52225211424167-1--1-113----------11-22C-2-21-31114-11-2112--443355--13--3253433-1---12---14221132122-633422433423232213345163---1---1-122221154121111111111-111112111111111111134432334221132223222221231111111-32---1----111--11-----3222-2413------1--------3434421-1-2422223722222341111311-121111113311111331227515555111-------B2233551653324141121--3-4575442342597143CCC1164211111-2-1 **IRvm28*9A244386A99777F9F8565555666344444456675DEEEFFCD67A76615G25427A9A167C38B4DED2A3146FB68DG3355357856-4FVHLMEDEDAA78898aD8G8T*E1GDM4798B69F97C977A86B7E9AD4AFP6E7DK6BX5F473345T64463A6ABA6644945A3 * c.1.9.1 Adenosine/AMP deaminase
[ 317] ---262-1--------61-----3222513-2oL--11--1111113B149232454712211-3-22 5BR---1-1------------------------------1-31421---1-1211--1--223141-2611-111---3212---2-166E9-91-3--38-54A3B47----------------1--12---228FF44-2-4-2111-1122--111-211212-411-1-----2----24112--112-22828BBD3CBDECB-33352CF521221-42446444B-33434213233322-1---5-1-22----1----13-----5221111----211-----------------11-11-1111---11123-1L6111121152631---45-BD443933-3237416111-1113---K2D5231-----1-2312212313412211222223-33133211-1--1111212222-1-22211222122112----------1---32------------11---111----------11221112221111241222122235222-33243223--22222223C1-22-212-1121-1111111--1-332B35323233444123-2252C324433OE--512-1----------------3--11113-4394242255BA661233321434328----411------16-29-4CRT8C99AJ4-L4CGb7EFD4TFWDDCGD8-----5391811121111221112---4----3-DJNJQRLROdJM--14-----2221215---1-21--1111----11111-2-2-2A2222523-12-2-1234--111-11--1113222226512521554553321111--11331144--------1-6----------------------11--2-1133435-341 14--AF8-2--1--212433--12-1112-222-1-2-1-------11----2-223132221-----1--2------------2----1-12113-2---4122--193SJKQQZUJCGABRDaRAUG**j5cR*DKFERCDPHDEG99YCAiEYKJY75E14F522E8AFV651---6--1112135262-312-11 * b.1.14.1 Invasin/intimin cell-adhesion fragments
[ 318] ------------------------------------------------1-111------1------1- -2--2---------1---------1------------------------11--1-------------2-1-----------------------------12----------------------------------2111------11---------------------21----------------------------------------11------1112-------------------------------------------------------------------------------------------------------213333333-3-----1-----1--------------------------3---------1--1-------------------1-------------211--------------------1-----------------------------------------------------------1-----------1----------1---1-------------2-1--------------------------------------1----------14C----------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------1--------------------11------------------------------1----------------------- -1--21--3111112133352324753112122--2--11----2321122233-22--45412113-1-31--1--1--31121-31113331162311212423-21C*******oihjllm*vo*r***4*h*jpolriowTYondV*mZ*p*ruiR**U*tsZoZc**QZ812-3A411112212342--22363 * b.68.5.1 YWTD domain
[ 319] --311---------1-3-1111232222332211-212111115223333235--111211-1-21-- 3452433344633343322-23223322222333334455353433213452656324223133235542332223333333222222322222221112422323222222222222222222222222222223333322352433333222222232224423444322222222222223422221423222222332222212322224221222233222222222222222222222222222222111-1121112211112112222221112222222222222222222222222222222222222222122222222222222232222222523112342223242232232222123223322222222445463344545422222222223-444463453621433755478845233233333333344333333335443332211111111-11111-1111111111112222222323323333334433333345333335436534522334423334554442222322323333333212432134334334343341323423233213223223222211111122222222232224223342263233423333222222232232322-2232322122244533445445554545-44545454554455555544544444445555555555454555444444542555555555555222222222343322335333333222223333333333322244333353343343333332222222222323233333333332333333333222222222223221111111122211121-111111111111111111111222111--2442 2212559-H563DCD5464665887886646467555877667454648766A75556667754355536554554543453445534358846564455695787-5A8FADAEFG7885A7BIC5M4V*F-CBL8B76H79A889579C77B9GDDE4787AA44947D89C69AH9*76669IDHK5ID887E999 * c.37.1.17 Gluconate kinase
[ 320] --------1111111-------------1--------------1-1---12----1-1-11-11--1- 111-422-111-1-32234-52114433333332224446242512111-12333333--532135444211-------13121---------1--------3121111--------1------------1-1----------11-11---2----23221112-1-----1-----1----11112---111111111111121122211111111111312111111131111111111111111111111---12-----11--11111---1111111---1--111111111111111111111111111---1111--1------------1-------1----2----1----11111-------3131----11-1112361113433122222222223-12211422132-333121253142211--1213233223111111112223--32------------------------------1112-111111111111111111111111112211131--11311211111231212----2----------11111223-323112441-1-1111---112132--1-----1---------------11---122237--33-131-111----11-11-22--1--21------21222212222222222-2222222222222222223222221232222222222222222222222221-122222212222----1111111111112-----111----111-11111111--4245541522733322454----------1111223222112232121221111111--1-221111111111-1---------1---------------------1---------- 11--216-413-121223263335353444443-3221111215436456554532433323112131133222212-11311113112143213522211223231D46*YiXlWkHINIQSJjlE*J***7*i*QGLQxJNWPRTQGB*GI*HiQOKg**8ykJ6J69C77I21--1L13322256B2152513111 * b.29.1.18 Alginate lyase
[ 321] 1-1--16BE77BBF931425311-9224-2461------112-21-1111432221--2312211--- 2221B324113223J7854-5C33E755555489DC88FB349312231332456344116691757758312222231-1-62111133-3-1--1--1432186413111111111111111-111----4-2111111113443121141--------414-12451-----------23443311141111111113212222223222212217521511221125311111111111111111212111-11-311111111111111111122222321111111111111122222222222221112221111-11121111113112-111211142-224--1--11121-1-1----1225-2412511111456697325544611111111112-433168212264211232444323393533442-22156111111119111114321111111111111111111112212111123542555458BCBC8A6779887A988978GD89JCG22IG65F46387536945434424211111112427AA31321232111121133314222211617C362321122222312111112111243321121354211412543311211211123231-121-211-11132131224333443444-354533353533322422565632332223132322334231243333332113224222442221111111115444546262221311111-11116556632111521131332244864512212212222233222333332232233433333221111112232----1--11-1-11111111---11-11111-11112--------212321414 6553532-A385767558442443415665544464545544523268AA35D4765824273312262124222222253324422347C45ACA635776776V22C797CAB9A84768A8CD6H5y*E3LERAA68D5BE364939885CIE7BE5B979BL5F55C49G52575s95656FFHK8KL86767C5 * a.25.1.2 Ribonucleotide reductase-like
[ 322] 22223222222322235232322332233632325234233223335233234323222222221222 3431122233322233233-332233333333343442322223222322222522122234224323323233322222332332343332122222223222324222322323222333322323923432222254112224734343334544334343345463343433333333322222221212222221111112112211111111112111122111111111111111111111111112111111111111122211121211211111111111111111111111111111111111111111111111223248332431111B11213111213112111311211111142242524332212343543324232221111111111123313413233222222224233333223223222422221111111131113221112111113222122222121222132231333222333232222453333442334332222226322222422222333322224323232222222223242232132312233332212144-532322244233-12-2322132333333342322322333226222213334323323222222236223224323222232322233433342322-33323332233343333324323322323223423323343233333443322222222222222222222223222233623222222322222322333233232222222232222422222223111111-12432423333342442A23233222232322432233332222322222111111-233221132123511233132355424431422 a*688A73L78556768AA58B7787B8859888757464565347548A6567466857A64643431644754742654645464457B688CA67453G685837D9Q8IEEGJ6475374CB6A6P*81BAB4655846D858666B64B8H7675GPEAIWE845XABG657B4b865B9hH9VEGG48CEFB5 * e.29.1.2 RNA-polymerase beta-prime
[ 323] 111212211111111221-----2111112111112212222111111111114-1-111111111-1 3443545555555555555-554465555555555585663333466555545555551145445684445555555533432322224444332331158675533432222222222222244434444444444433---4365444444444555555544444455555555555555455533344333333333333333333333333344433342333333333333333333333333333333433433333344333333333333333333333333333333234344344444434355333333333333333333333333333443433343343344333443433343343333545455445233333333333355554555555-44444443554255555555555544554232222222222222222222234641111111111112222224221221111134434434433455454444444444444444445444343444444333443443344444443454444344445736345453555554242344433344355442212222222212111111132325335636676456674444555444454554551123423------56666656666665665-66666666666666666666666644566666666666666666666666641555555555555113433333433345345444444434344444333333433435333344443444544445453443543566655555656664444444444333332325533332222222242321213-323133233333223333322222222121425 5522962-K96122222221121111111222211111-11112111112111132111111222223-22221222122221222-11-2-2--------2-333-3R372439643333333763423G3-3373231442342433452233643233335-52244232456BBBXB8878756A2787D7J559 * c.116.1.1 SpoU-like RNA 2'-O ribose methyltransferase
[ 324] -----352111122B3-1211--14222-531-211221111-214212-C33-2N222231111--- 2-12C11D5631-22--22-2B--5422222q689A418F4118-3152--2323-62--226-4-E54212---71---321--3-11213-21-D--111--D-5E1------------------152321-5---11146237361225---11111--2112619311-11--1---2-1-1-12-2--323232221-3223924CC22124-1224C-2--123411-2231----22--1231621-F5VQ2G-37233252412223F-1242L911---132632341621I32E13444462---DAA---1153-2-1--1-132-1533---E51g--3263-31522424266B531--3-25662----D-166781-5231-21252332238-45H12316981-2445A14B67961D114H821K--A71SQSSSSSS7EB7-B32--------1----------2--------1-8361323A4q22442-82222414A47A5432zJ233B-265M11JB181-4113751-1--2-19316---681414612247812462---122-12521226543--11-111112---------3111112-9-332-1116-R352A422-111621211---1-22------2143753DA8BH73BI3-78D7A835486B744H444D57342U-33366943754777773U4*cZad1-966687367285--22-----122-611-242211123312113-411225-4-76512131332-32156U63l1---21211C217-4--4J228123EEH9Aehb-------133------------4------2---11--------6-------31--------1-1 -1--11-------1-----7--1--1-------211---1-111-133-1--------1-5-111-1--1-1---1-----111-1-----1-23------61-9g---334---4111-------1339L4-44312--2--51-2--121-31-14----4E245D2425-21---1------1--41-1--7A68- * a.4.1.2 Recombinase DNA-binding domain
[ 325] 44435287899889976544456276655647345223232325445667676267554554341134 4484554555544354444-45444444444444445564555522321333554332115212633856322221224123423233764413221--142214234311111111111111234344534545A9A893446376444554354433233354B55563433433433355452232224356566565676556638443666724516441112113931111111111111121112241245222224411641413224343444555444344344344344444444434444456222445455-76222333452774776544117235343365764144233434334323433211111245554424445311111111112-53554544452245566656575433323254555532-4444444443324953-----------------------------1132232111254545644444447755554556944643334433322232434444544442334444355544443735242242322453554443355454434222113322431211111114111444665344246166566436555445554466--24544------44445455444554555-45544454544555555546444434353345545554555445555555341544444434454--212222222223352432232232222222222222333423523335353433333555423332332484333333366446233333333333332173443333111111112-2------1-111-1---3211-----33445533544424 2133336-63234442332342236223332223333333344343332243322322233322211111242231212122331133412-31--423443254623A454654521131243B5282DI5-44313215234112--331-43224438339333534A47733594n53555IADI3DB-254383 * c.68.1.6 glucose-1-phosphate thymidylyltransferase
[ 326] ------------------------1--1--------------------------1------------- ---1---1------------------------------------1---------------------------------------------------1-------1--------------1111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1-------------------------------------------------------------------------------------------------------------------------11111111---------------------------------------------------------------------------------------------------------------------1---------1-----------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----gcL-----FBI22335542555633333322222223233333322555646643333------------1-------------14642666-1-1232332-PSFfs*pv*sfXZMaeU*oQ*a**o4*r*MdabuZgyWKbbYWnWK*ixdcmO**LUZQR*PhVCElT-573p---23GRfS3RA6387779 * d.109.1.1 Gelsolin-like
[ 327] 22222233222222224222222422222422322222222222222222222222222222442-22 2222422222222222222-22222222222222222222244244222242222223224423423444244444442223222222222222222223422444243--------22----222222222222444662224422224422233222222222352322222222232222235422222322222222222222242222222222232224444442422222222222222-22222454455444444444553544424444444444444444444444444444444444444445444444422346222222262422222444422222223222222223222222224223222722222243224224242422222222222222222222324222225422222222223222242223222222222422222221222222222---122-322--33-222222333222222222222222224424222224222222222444432522246222224222422222222222422234222222422222222232222225244243222322222322222222232334222242222222232222222222424224222-2442222222224222222222222322-222222222222222222222222222232222222222222222222222222222222222222224222222433425242222222222222225555544222522333332225242622222222222222222222222222222223222222222222222222222222222322----2-222222222222222222222222222222422 44--664-L892667888797778777777977877775777797778777897897AA9AA98AAAA599CAAAEC9CCA9999966845584455444465BBG-585BCOB69C96858A9EF9C7h*E-ACN86B8E89F988998A86G8B98D46765445J6966D656336k64643C8SD7B66487649 * c.61.1.2 Phosphoribosylpyrophosphate synthetase-like
[ 328] -------------------------------------------1------------------------ -------------------------------------------------------------1------------------------------------------11----------------------------------------1-111--------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------11--------------------------------------------------------------------------------------------1------------------------------------------------111111111----------------------------------------------------------------------------------------- ------2------------------------------------------------------------------------------------------------1---1K-*******cbgbfif**e*d**x-*l*YgZZ*ajxcVgdbUjcS*cyfjuLVd***UNmSM****--3--1---2--------------D * b.96.1.1 Nicotinic receptor ligand binding domain-like
[ 329] 33232332333333322233333433334323245334333344444445555534322133324144 2533583344333334433-3333333333335333333334433333333343333322333333333433333343223333333355564523122352556346522222222222222344444444444444453333233325533333343334543433333333333333333333333345655555555355555545666765554444235555555433333333333333333335432244232214433441323333333333333444333333333333233253233323333333333337344444444444433555333543124344344444442443334214544333433333553556535353533333333333-3333335334523443334333345544633333333433333333343333333222223441122222222222222222222433434333333333333333443433333433433333334334333444333333344443234433333333435544443344333253443335544446534324333333232422222224333366775644549756877766577776655755112533322222255555555555555555-55555555555554555555555555555555555555555556555555542555555555665222633333333344334424434244433334333333433353335333333343443335112132214578777777777664446466555444433433333331111111112211111-111111111111111111133333444443332 2111115-5331333322133233533444445222322222243433432353452232222523331233323342532225322223822524212322266614634231121-112-1192311-311122--121112-1-1-12-1412344-3222231112334623565j57564AAFE4CD639B763 * c.73.1.3 PyrH-like
[ 330] --------------1--------22222222311122222222221223332213333333-2272-- 1111111122211111111-11111111111111111111111111121111111111112111112111111112111111111111111111111--1111111111---------------11111112111222113331112211111111111111111111211111111111111111111112111111211111122111111111311111111111112111111111111111-11111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111211111111111121111111111111111111411-111111111112111111112111111111111-11111111122132222222222211111111111121111111111111112-11121111111111111111111111111111111111111111111111111111111111111212111321111111111111111111111111111111111111211111211111112411112111121111111111111111111111111112111111112111211111211222111111111-1111111111111111111111111111-11111111111111111111111112111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1111111111111111111----1-11111--111111-21---1111111111-111 77337674OWA88A748457556746644444445444444446566456658535654565433333433424344354333343444578855654544649AB36VUbSXXRQEFIMMLJaNUGqL**T1bQuHKIEULKQMAHHPHQFBaJVFKTFGkDc*CGHAEeEHVF89B8*77746XHZc6O*79EDDCI * d.79.2.1 Tubulin, C-terminal domain
[ 331] ----------------------------------2-------------1------------------- ----21111111-121111-13111111111111111111111111--11111111111111112111-11--------11--11111------------1-----------------------------------22-2111--2---11-11111121111-2-111-11-1---1-11----1111----111111111111111-1----111-------1-----11----------------------------------------------------------------------------------------------------1--1---------1----1---1--------11------1-13111111111111111111111111111111111-1111111121111111111111111111-11121221111111111111111111---11111---------------------112111111111111111111111111111111112111--211111111111111112111111111111211111-1-1-1-1111111-111211111----111211111111111111111111111111111--11--1-1-----------------1----1111---------------------------------------------------------------------------------------------11111----11211---------------11111111111111111111111111111---------1-----------------1-12-------111---1111-----------------------------------1--------1-111- ------1-2---------------1-------------------1-----------1---1----1111-11---111111------------2-1--------1-----r**t***mkqnmpp**u*o**z-*s*inok*osxuYrjod*mW*uYPruShVHCBJ8MAHR88671---------1---------1--- * b.1.15.1 Integrin domains
[ 332] 111232111111111111-----8ICEEID7D144443566656432767BB952323343112--1- 1323623111132345533-34--6333333453336386266443223111443442--664332546531111-1113244414313353-3221--13-83514D1-------111----222111411246655B9555348D99AB956552222337A76A9A42322232222222232311--4444645545455555526433554533324223222212422222212222222212211121-11-2-1-221111-1-11----33311113443333333333311111111111113113331111264-1331333323222111111243524332365153547251112133245444333334332252226364444444444426-6546553455613441222343465664555234336331111111122212344111111111111111111111111121222466314555546676544555443444442454245541243464644545451477455635434554434278626B89886379448342432525421414587332332222231311111115369844973564648675666656676666865655--26433------55445548888887888-78688888688888888875654444555556556656565555767666632555555555555--24-----3113565565444333333354426676654332445555766665645764543332422335558555556876653443454431111329244333311111111441----1-1111111111111111---33433331332-4- ----4421311-111-2--31-12-22----1-111----------12-11131--3---1--1---11--1--1-11-1----1-1--24-2--11-2-2--222--5755B3F633312342CE1F2Wl51C4821218345333121A12B2B334268C631-H11123212222N11123B6B9-682498BC8 * c.2.1.9 Potassium channel NAD-binding domain
[ 333] 332-3412111111122-222223111-1-1144411-443319D45752CB9135-2445-3-3116 3--29122333432CFC99-9D33HM999999FIJIA8CF1C7A31-1-352111322--78B2F6J4AB3111112221483221--CB871A55---4523454512---------------65378435435233122236256553331111-1-1--31437676---1----11-144333445239DDDDDF9E8BBDCCB466668CCC312A465677655H85444344644444444445543225424525553345323221668333333324522223212222333333333333322233311122D8FP89788981817D6522339124624245BC234438223222233223844311111658AA2116344633343333333-43633933445-4777443545437A44324523322345455555515643342-------------------------1111-44551255366338538577788BA77772876A3997133363525475666-63526456244333331-14453JCF65A93A6666335357557824421B6511221112311112222-2222-3132333444423333222234522222255235--141-4------44433434445455444-4554444444444444444444442133323322333333332233434443-211111111111--12--------1536365554452222232246676627335927777555366454534622222222232333333336644433333332221111114222------------2-111111-111-1-----111--1---33122343232363 12---2--3245---214184323332113211321--1--11121233312661-131111211-111-31-1-421122111--21113-142222211-2-12-16362121211211122121218H1-426-2112121222131211122321-1-141251124123--1-211---142-71523565453 * d.90.1.1 NADH oxidase/flavin reductase
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p7-99G64558545525866653A5435524358432522413531122S1121285EA5581345478 * d.54.1.1 Enolase N-terminal domain-like
[ 335] ---------------1-1-------338-----1---------1----1-1--1-4-13-1---1--- 6331F---1-11----1----2--2------11-------5-11--3-1-1--11--1--24115-A8C92----11---1-------33E4--------5--17-23-------------------1----1--11111---61-1-11----------22------2--------1-------1-22-4-275757456355755625552566523433--33333368-----------------1--3--1--1--1-------1-----111-3--111--------------1222211111111-22---222-12225666666645161221---7151-5113133222132-1215----2--1---------11------111------------------2-------111----1---22----11-1-------------1----111-----------1------2------------1111-----1111131111122--111111212---1----2--111-----11-1----8-1--1--1---121-2--1-1--1----------2---1---73-1-----11-11--1--1---111-1---42---81-1--144442-1322--111--6--11--1------22--2--1--11111-1--1--1-1----11111111222--67-22--2222224222-27-------1-----1----111---112411343311A------11----------------1---611113311--1-2-111855555345-144676775B8378331212211111111---443333----------1----1-----------------------111-1-1111- 12-18K9-933-87CFBLCMMQGIHKN78BCBALQJJBBAAA9666DHNePOaaINLIACBC555222-52242422244245585111FNCBCQF4455BV5NDJ-4I4VKVGQFLC9C779BUO9UFi*K-TIOAA89H4CSD75B96C7BV8H5FB465BPj*Usvw**rF71C81813372LakaEFM3N76559 * c.1.8.5 Type II chitinase
[ 336] -----------------------------1------------------------1111111------- ---------------------------------------1-------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-2-----1112-12221213-133232331111133-13---2112313-2--1-1--51--1121---1-212111-3----3311-1---141-43512--*iSgQ*WWSYWNUK**Y*f**w6*y*eVZVHXbxhINUIImcS*ET***J7fLitFQ9Ths55*6-1--------2232-24--3331- * c.52.4.1 TBP-interacting protein-like
[ 337] ----------------1------1--------1111111111111111111111--1----------- 1-11111122111111122-211111222221111111111112111-1111111111--112112111111111111--21111111---------------------1-11-1--------P11111111211222221112-11111111111111111111122111111111111111111111--211111111131112111222221111111111111111-1-11111212111121-11-1-------1---11-------11-111-------111------------------------1--111-----1121-------1-111111---1-1--111111111111111111---1111111111111211111111111111111111111-1111111111111111111111111111-11111111111111111111111111---11111---------------------11111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111112222-1211-111-------1-------11111111---1111-------------------------1111------------------------------------------------------------------------------------------------------11111---------------111111111111111111111111111111--------1----------------1-1--1------11121111111---1--------------------------------11--11111111- ---1CC--211-11333E53444544443334633334332355448524435643442322713122133321211-113111233232D4334611212213J7-49i*ndYVglPQNLRuW*yO*M**n9me*OSRIjOasZNUVOMdNJ*SYaWZYaPK*T*8IDLOCKPK2621G21143J7GR6VA625876- * d.154.1.2 ArgJ-like
[ 338] 111111111111112-2-------6456-17212111-1635311111-14---1111211111---- 33K13-3233224354222-262253333333J699A7MK26AI322342118282522154F2559244323338674525121-11OJeO2R833--3726544931222222222222223222325342532335424593A67211121---1----4--154A1-1---1------262432234325656678536B8457345523246734B4245222546248D27336328884245B52B7553544446557744373232569356423123242234623435535542654344413211152343A4492312543753846533324332422DA473FA9617-224222313398223222232364H8322313433323232335-653667437K22412922GF236847423D24352335377777777C22425232222222222242232222222222222214A3522322B98B694B5655ECEK6643347I736NK22EE5864635AF4433394342411122222453K36339411154E3431411364345A32512545-52----------11----13-2-3A84837B312535488A735475691D67736--26323------35683445784554763-7758449444735345433683C4GI77543344385577538954333332-734324444622--131211243473243223224233221232253448334223336A3353747478389711111111143359544746525672336352232121--32442222--------323---------1--------2---22211111121112752 1---2-1-----------1-----------------------1-------11-1--1--------1---1----1------33312----2--1-3-----1-136--4-211--5-----1---------------1----------2-----1--------121-------C--2L---1---1--41--1-33-31 * a.60.9.1 lambda integrase-like, N-terminal domain
[ 339] ---------------1-121111-41144242331--------46325--534-------11131-1- 236251211221-223333-33223432333224442323-43243-332312531-2--2273333A7522333222-2232-1--26677-344---46256636-512333321111111-4442322244233324---3-46253332322222222332343332222222422223222-1-255344444755445466522--4-446211215711111214422222212222222444433435445533333445423233321111121112111111111111121111222222121111211113-2244222--1122312221222321331562-441--2-2---2-1-263-42333-3333242223233323333133333333-63243332275-44433464644524222723343321-3333333333332323------------------1-----------32243354549677783333355665443246A99666--5564467658359244856325254333442534456331222211111-14374562324483B7241222222222234443334422-27775553623332554434234444353323523-24344---11-55435444444445544-444444445545444444443655333544445444444544444445535313333333333331113-----3333342341111311111111227773456455437667457646666578A42413223233334444444455355787876883333---1332222----------1--------1-----1-111---111--3-------2622 21--871-422-13365647555745555555534344233243335677776856776988222222-22122222122222222222352533454453348A828337JDIKFFA268AEAHG6JCV*E-JEM8988EACC82B988C66I99ABB34824222722514412--15445-1IEGK4F7-1FLLJ3 * d.136.1.4 Polyphosphate kinase C-terminal domain
[ 340] ------------111--------11--1111-2-----111112-12113624-1212221111--11 4252412433322243344-43223443444344445564244554533222565322223243437552321112111223422222444413442--333434443422222222222222355344343334111112221244554432233222224443345532222222222224342211233333333536334343343445433333336332222224533333322333333333333223223232223233332233323233332222222333343333331222222222222222222222233233444444454434333333234322433333333434333323122225122122222224633243323233333333334-4325353434226325345434332222223412113222222222223321332222222332211111111111111122221223122333222242232222224333342332343542322236533622252442222232222222234422344456333434443243354355533344634211111111-111111111142113223331222333423333433345443333432-2422222122223222222222222222-2222222222222222222333324322222222222222222222222222222222222222222224443334334234422222222222222233333342322433336533322233433222222222234444335344553444545445522223331221322--------11311112--12-11----12--11---22122222225433 3233CA7-7223665678525667587662656344365514555555557767675656664545362545354452555555544554847474999444684524C44AAAAAAAA747H6LH7PAk*K1VLO4898F99BC8FE75F6584884854436322455A56C46637T77777A8CE6A89865756 * c.97.1.2 Deoxycytidylate deaminase-like
[ 341] --1---417666362221211-12312411-158--1-112223521213136-3-222141-1--22 789482--222----2233-32---144444-212134-24233521212323673231112-172-463-43333342-631-3-56JHGB-D24---3B7A679B2B--------------87451546667567796112328FIPHGA12221212-43A66MPBE2-2--3135-15211212213277595A89636877887666767451112611122221752111111111111111111182-224322142411631-221452A4662333522312413852511111112111111822334222--11CA6666666685241113--3111137322433333111--21-214325-21------5522423231152----------6-86A8799949118553DB6A8B4433822-2-41343214444444456666543----------1122333222222221-11-21521-111-4668544688866558788774771211-31322113--2246-5655333222313322122272-51721BC9867793FFGA6BE7A8A6862531131333275116111111111115333236633-411-1-3-1332211-132151---5222------2433-122224254444-142452335325343244342332355111111111111111-2-2311311-211211-11112--11---------8342-434344233223-2722332-4---75752648B331176-85471111211115644-----112112364444332----1-41556665121-1-1-4---------1-1-12---1-32-----12-4312111476B --1-446-----DGE85654446555344644455468466652338A777AB968658777521212-12111211--1122121---8E6587C6556849IDG1384M8888C3434287674572DX616574425734562542333374659933446422321-252313428213-5D24566413---14 * c.68.1.1 Spore coat polysaccharide biosynthesis protein SpsA
[ 342] 11-----111111111--------1---2-11-----1----111-111-311--------232--11 --3286566665669BBAB-AA779CAAAAA99AAA9ABD498C94643673788546226676A9999C777777773-142233333324-443---112--2112211111111111111311111111121777562237-687355423333323333457475313221113-22165723111221888888972989897332222997322624377677636-22222222222222322224887997678999998856656754433354444444444444444433333333333236543633333233371112---2-2123212225151-2212132212--2-12222343112422511111333442222231322122122113-77678847465164438836654534473-3211113436666666645533222-----------------------------112212222233333335444444544444443354543124455344444545334211112-1111111222331324-2223141223-212122232112133-3----------------------12111-111222162112122-31233222222411-3222111111122223222222222222-22322222222222222214332234233434444434343342222222211322222222222111----------131112223221111112121111111-133223332531242221432---------1---1111112321233454554442242-1-211223311111111312--------------------------31--12111211- 2134434-H63234857666786779444345344543432335537A346A57745642434755352784858664364ABAAE4455A473533647498331-2q5-887884667446459384Aa7-46F3665646A655548466E5454723215221724146214BA9F67869HD7K4IIFMAFCAR * c.60.1.1 Cofactor-dependent phosphoglycerate mutase
[ 343] 11121122111111121122122153345323131111222222212221121111111111123122 2222322233322222222-24222322222244444333232322222222242232113232323333222222222222222222222212223--222222233223333332222222222222222222233332113224523522222222222232223222222222222224432222223444444444444544434444444433354233333332433333333333333333333323233232223333333323312222222222222222222222222222222222222322222222232233222222222222222222232223232222233222222222212223422322222223223232222222222222222-32233222222233323233332333322222222222222222222322222222222222222222212223222222232322322222222222222222222222222222232222222222232223232323322222222222222222234323322222222222333222343333332233222222222222222222232222322222232232222222334222232432331-2222211----22222322222222232-22222222222222222222222222222222222222322222222222221222222222222222222222222222322222222222222222222223222122222222234222222222222222222232332232245252223233222222211222222211221111121211112-222122-11122211111152133232422222 1221954-94333435574F343647633421321444232354259*3933B73357E527K32222263554322222256425123HAB56DK32533O915*21IJ475*7412221242653223J52232122-212S21221-221423L2E5E4bbITq422K88542352F324516ICy3m97CIQ**2 * c.55.3.1 Ribonuclease H
[ 344] 222222222222222223222232--------222-------------22122222222222222222 3333346344433333333-33333333333333333333333333332333333433333333435333323333333223333335111111111121111221121222222222211113221222222212222222323323322233333333323232443223222223222233322332233333333333333333333333333333333333333333222222222222222222223----------------1-----22222222222222222222222-2222222222222222222222239322222222232333331333223223223333343332333333233333333222222332333333223233333333333-34333333433233333333333333323333333333333333333333333332212222211222222222222222222213333233333333433333333333333333434333213253223221122413332224333333333333333322232222222222232333333333333222222222222212111111122121222232233333333333333544334333332-3223321211133333433444244434-5524434444434443443444443343333113111433333433333433122222232222222332222233332333333333333333333333333332233333334333334333333322222222233333333333333232323322233332231222211222222221221111---------------------22122222222331 55566682E664666667756667565553566555466555566658666664767877576556665666766776666665677674766966666647668657B6LBBAD878877989BC7C8KtC1ACH7778957866A878AA6B677798C67H7G9C776CAC696AB*9A967A7CK6ECBBB8981 * d.14.1.4 Ribonuclease PH domain 1-like
[ 345] --1111----------1-1--121-----1--1121221111122-322211112114221---211- --1-1211----11------------------1------1----1--121---1--------111----1-22222224133--22-33354-411----2---------------1----------1-11-1122221------1-1---112-----1--1-11--1-----------1---1--114-2-2222222222222231122--22211---22333343-1222222222222222232-121-122111113311222211112223333333333333333334333333333333433333222333327536555556565535446443833121221155483222211111223-12---------1---11--15112------------11-11-1---------------------22-3------1--------111---1411-1-11-1-------------------------3-11-2111111-22222211222222-413244--443-1-221-12--31-11-122-------1--1-128335246335443-13-21112-----1-2-31221-----11--------122222264522-211-32433333424332333343--2----------74336637987799877-57777787876877777785864432676767677667676664767777621533333333333---2--------------333333344443333------------12211-1------2-11----------35553333355444-11--------------1----1---------2-2------------------1------1111112111113- A72334F-ZCFBEED2441332344234533232312445645222521235252245321331323113211312122131214161247543351123231444227FtCEDGGUEFEDEGIONDXFl*J6PGfAGBDJHHK9CFHHFVBAUGNCILR**HJNEFJCF*99SJ1HLF*32565C23545C4ANMLNK * c.7.1.1 PFL-like
[ 346] ---------------------1---------------------1------111----1---------- 111--------------------------------------------------------------------------------------------------1--121--11111111111111-11111-111-1--------1------------------------1--------------------1---111111111111111------111-------------2------------------------------------------------------------------------------------------------------------------------1-----1--------------2-1-----------21111111111--------------1------2----------------1-2---------1---------------------------------------------1-----111111111111111111231111111231111111122211111112121-----------------------1-----------------1------32---------------------------1--------------------111--------------1----------------------------------------------------1---------------------------------------------1111-1-----------------------------------------------------------------------11111111111111----112222-----------------------------------------------1-- 533566C1G78556F89B86786687699685755586666667789B9888BA7AA97A98533333-3443443424433333344669998CB87865B89BB1A*7QWZhgtdQNLKQWR*wLwN**hCtZ*MQONdQUaQFUPNLXJGeUYaNYGMQNOHJCOGFOKZKE5LBGqDC9CFSPNkAbQZXu*ZnI * b.85.7.1 Histone lysine methyltransferases
[ 347] -------------------------------------------------------------------- --------------------------------------1---------------------------11-------------------------------1--1--1---11111111111111--------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------11------2-1--1------1-----------------------------1--1--1------------------4------1------------1-------------------------------------------------------------------------------------------2--2-----------------1-----------------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------1---------- ---1GD7----1HGP34444665647755454543465454455556655568B4475565643554435334542323333453523343344345365454KFJ-G5*T**s*rweZZ*dZd*wQ*V***3*n*WUTWqWcwWRcYXKrWTwZuTdbNNbJOIKBNGHOIZEI--1-------1-11621-3GNKNA * a.91.1.1 Regulator of G-protein signaling, RGS
[ 348] 22323333333333332333333211111111211-21111112222222343111111112222123 --1---------------------------------------------------------------1-----------------------1--1-------------1----------------1-----------------------------------------------------------------1-----------------1-11------------11---1-1-11---------1------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111---------------------------------------------------------------------------1-----------1------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- GD9FJJE8pIGDFHFHGGEDFFGEE7FGGGEDCHHFAGFFEGGDEFEFHGGFDFCEGCGECDEAHHHFACIGAGCGGDDFGGGFCCFGGDMGGGHIHGFGEDFHIGDITGVLJLIKNEINFHXJSXEbG**h-VO*FHJIOGHRIJIJIHKFEPGHHMLJ7DILKICNHJHDNJIIIGI*JHFHGcPRdFYIKHJKHGI * b.38.1.1 Sm motif of small nuclear ribonucleoproteins, SNRNP
[ 349] -------1------------------------------------1----------------------- 24914-1---1-2--11----1---1----------235622264--11---121111--1-1-3314521-----1---1-4355432223-3121--2223324222---------------1112112223112211---221122111111111122111112111-2-----1----11-12---512232344332543462334344326111321111122233121111--11--2111211-3---11-1---21-11---1------2111111211111222122121111111112111322332312124236444445445326332121-321141122333522-33222231-123-6446343438AFBF879AC979BB9AAABA99C-DABBCECAFD91AAACAB9BACC97B323B8A9A99989888888886DB9756511--------112222222222222----3766645766CB89C9B85565AA8A5556469DD67AA35C9A77BD7889A7665B5667554544434475C9A976565543848B846587565596665B668223222222233433333333322476BC6676867669999999A999988A98991-65877-1-11187589876666676887-7668889687778766668879A658AA8777778879A9A78D787977772A77887777C7711665545466668765444444443333422477A8787667678899778A686776B883222222226BAA865575C876788C8A88776643531A43322221111111122--------------------------3-1332122211-- --1---2-2-1----42---22--1--111111---1----1-1112135--2---1---1------1--------1---------11112221211111-11-111-----12--1----------1--1-------------1-1---21----11-15-24-211--2--2---11------3126-15--6---- * d.2.1.6 Bacterial muramidase, catalytic domain
[ 350] 33232478777777772444533465555644335544555553333434454555646455763-44 5472334333337235544-4222634444462222633333333342333233331322323443334323333333312322222233431322-1145354436231111111111--11122222322223666661224223233332222222222232322332222322222233323333232422222233323222333334322333325216666662425555555555555465556656466467446655675665745565555666566555555555553344454445534655555555533253444444424233332222241132224222334233323335125312211111111112111111111111111111112-22122122142311111111121111112121111112111111111111122111111111111---1-----------111113211111111211113133331114333332112121111111311111111221111222111111111122111433211121221113212211112111136212212233323222222322222232113443132133443434333333343443351-3111121122233333333333333333-332343333333322332344433363444444444444444433333333314333333333432221333332333312114444231333332331111--1111121121211211112312132232333232333333333323322222222222222112433323333333333423--------12-1-1----1---11122322323332523 11--668-G754665555555658555556877575475555555565555576555575555554662556547662665556655555D75466766587767736J5A8966975424756EA6F5EZ7-C7A25548477437553542C4B44467557645575748862846n68575CDGO5GH6756B78 * d.14.1.5 GHMP Kinase, N-terminal domain
[ 351] 11332332222222231223122234434424123113322224446422323632333341222123 2244333333433344444-455534444443544445564443333533343234334433344544543344433333433332443333233341243333333433333333243333324343343324433333443334444445434444444444334444444444444444334333333333333333333333333355353333334233333333433333333343333323334343433334343443333434233333333222233344444444444333333333333333343333343443444444445442344444434334433344433333343333333343344445444444444444434344444444443414444444444445334444444444434444444444444444444444444444222444443344334433333333344443443434444433343343444333433333333432434433333333323334343333344444443333344343333453444444333433343433343433332231212224443444442232344444433434444444444444444444444414343444344445444444444444444-44344444444444444444444444444444444444444444444444443455555555454334443433333334433444444444344444444444444434444433334333333334444444444444444444444443334344443333343433334334444544445333334-244344344444433422254433343433333 2-22223172311111112111121232211111112111111111111122121111111111111111111111111111112111122111112222212434125173333223332231661344L2-2532122333243434332443542411124253235524364244Q4562484CC1564423242 * d.52.3.1 Prokaryotic type KH domain (KH-domain type II)
[ 352] 111343131111111111222119KFHGJKBB333432222216346857CBA24443433--12--- 122154422222-133333-34116233333542223454343454432223334482--554341647932111122123364-622KKIK3I662--52-A4232G2--------------111---32--26AAAEC333527C88A963244444455675875614434444444444654411-235556565664666666364425666413554411111123322222122222222222223322232322255443223143-2225553222455444444444443333232232233522444222316413775777737434334876375456441444282446162112255149211224444-16--2-------444422244-5-1-41-3--6-9--4423424446544456A78686676622222222-----454--------1--------------------22422245522-1111-211111143122212113675611111212333111112533-1113333333321-57267JB96H747C335526363A39234466777223421111132222222224455711DC4781775676766757677765767687--45636------97557A48888888888-88488888888888888889997744699999999999999999888888832877787777888--3822--222-227673666456233336446--2---11213455555433C5655B3334322244233888755555898772224244222222244B322112211111111541----1-1111111111111121---32222231221974 ------4----------------------------------------------------------------------------------------------------114----1--1----1155---------3----4111------1------11132-1------2-42-2C54P465518466-364553-26 * d.286.1.1 TrkA C-terminal domain-like
[ 353] -------------------------------------------------------------------1 --------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3312887-B59256898G8CCHED7CEACAB7BACB9979899CBAFFCFCDHEBBEBBCCD456869359665689796755555479FyB8IGB888A5B3EHF-A5GdUXYfaYQONQKWS*wW*L***B*h*SLUPdQWbQQYLNHcON*OdQTLCEJJIIK9jFPQBNEB755AW75544VIQm9*B76DHJI4 * g.44.1.6 ZZ domain
[ 354] 222-34314345443153333-453233443821112-353434324526A85-13-414-1121124 -1-13----------1--------22-----211211-11-21-11----1--2------11--1--14------433-1--------1132----------11---111--------------1-2---1--1--1121111--1-----2--------------1--1-------------1--2-------------1-121--1------12---12---1111121--11111111111111--------1--1---------------1---2-3-1-1--------1--1----------------11---1-11-----2111111211-1------------31--1-1------------2---1----------------------211-212121-----------1--222--11222111----1--1211---22222222---1-111--------------1---------------------1----1111--1111---111111--2---------1------1----------------1-----------11-1-1-----21213112311----1--1----1----1--1-------1------11--1--1-------2-1-1------1-------1--------2--11-12222222212-2212222133222222221112--21-1111111111111111122122221-----------------1111111----1-2-------------------------1--------1----1----1222211121-112-----21-121--111-111--------22------------3-1----------1-----------111-21---1------- B99AHIG-R8B6HGGEEGEEDDDCDDDDDBDADEDECECEDEEDCCECDDFFEEACFEECEECAA7786796AC9BA59A79A87ABDDELCECEFFFFECGEFGI4FFDWJTHJPDDDC9EHBUO7VDs*M2OKVD8HCJGHPE9IGCCJE9RFIIKGJKODIJFDJFJeFIHFCCFE*FCDEHZNhcERHDGJEDHA * a.4.5.47 PCI domain (PINT motif)
[ 355] 22121222222222222222222222222222222222222222222622442222222222222122 3333222222222222122-2222222222222222222232222222322222222222222232222222222222222223362344442422222222222223244444444444444543222224224222222222344224422222222222422222222222222222222222244233333333333333333333333333333333335555553322222222222222222222422222222222222222222222222222222422422444242424443444444444422222222233333555555555535335444755543553333333353333333544335344322222524343333333322222222222-3333333343323222334222222233343252553332222222222252453222222222222222222222222222222223333444354446547575445588883734843332233433333342543335433363222222235523333523553335444433333357766463252322222222222222222222233222352333335353534355433343344443222432333133343344343443333233-443343333343523322322244444555555555555555532334334635666665665652242222223555428352222222222222222222222222534434333353333345422222222233336333337553333444444452222223522333333333333346----2-242323222253225333332333533534322 4434334-E65234444264444444444443444424443434443344444344424444434444234444444354434433444454434744444429CA246396967A5534466595485Ba616665435916675523454363B44645C56454B45D58346454j3333398CD4A64453344 * b.49.1.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
[ 356] ----------11--------1----------------------1--1--------------------1 -1--21------1-2-------11-3----------1-13-331----1---211--2--31--113--2-----1----------1------1----------1----------------11---------1--22232---315321----1--------3--1364--1------------1------------------------------1--------------1---1-------111-----------------2-1--------------------1---------------------------11---321-----------------1--------2---21---1-----------------21-------11--1-1-1----------------------11---------11-13-----------1-----------------1-1----------1-------------11----------------1------11-1222-211--1-4--1-------------------1------1----------1---------------1-------1-----111---1---1-----------------------1-------------1-----1---1-----1---1-------------1111111111-1111-111-111-11111------11111-1---111111111----111-------------------11111---1--3------------------------1--11-1---11-------1--------------------------1--1-111---1----------1--------------------1------------------------------ 31-135A-743161GACVJCJFJLKJEFGJDEGGIB99A74ACIFHADA8MOEQDOJIDADE91-2131111342-112-243437511GEFCTJbMGHWAW6-92-694*NTgLTNJKMNOYG*pC*G**lAtX*CIGHiJPqP8RFKLkFEmFHAA*OJS1GBK7RAA89D*212E-131311549BF33CC189D4 * b.121.2.2 Adenovirus hexon
[ 357] 11------33333331-2------3113-91-------------------1-1--1-2---------- BFH-R--1---1-------------2----------23332--C7D6-6AA-3421-2-----5935EF33A5554331-12------UT*g-M77---BP-A1X44-G------------------------1-33376---5-1--1-------------------2-------------32---A9-4---------1-------23111---1412--11-222233W---------------1--133123312111111114312122221211122221--111111211111111111211111-3322233316---6----------A----5639-21--38--11----6---13-7---3-39331-1----1-------11------------3-11-111132---855788397833--412--------1---------111----2-------------------------------6-2-----154444613333443-4444336431644--------------22----1-1-----------1---1---------1------1-11--------3-----------------------------52531A2-B-22-1-1--2----2-22-21------1------34332336776666666-5646666666576666663545222--241223222212122153234446--233333323333-----------------3222224------11-----------1311111111-11111213111-121-1-1557-222224-6644AABAA7864444---21111----------1-----------------------------23-777681I71 ----65H---2---2FDIAKHJBLFJN3333335644222-2231188GNMNaLGBJEGBBD245-3--1--417---3--22121--16E7D6A52423492421-4P4*AFAJFFA896AGAJM9LAu*N-RKR4978ICCJA3DA44F84KCGCCC779irl94933BEJY9-222N22248ABBED9733PKQS8 * b.1.4.1 beta-Galactosidase/glucuronidase domain
[ 358] ---------------1---------------------------------------------------3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------2---------11------------33---2-----------------------------------------------------------------------------------------------------------------1-------------1-2-------------------1------------E--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --KJ-12--------------------------111-------------1-----------------------------1-----------------------------3*grmn*jedYVfxb**W*a***4*m*TjYPycm*gRrfYSbUP*Z**idPq*cYwVVoROrHK*b-KM--1-1E1--6-----6beZk- * g.68.1.1 Ovomucoid domain III-like
[ 359] -----------------------1---1----1-------------------1-------------2- 11--2-11112-1173411-13--2111111223334588-1-11--1----11---1----11222521-----------------------------11-121-1-1111111111111111----1-111-----1----2-3111111111111111112111111111111111111---------1311111111-111111112223111-1111-1------11-1111111111111111112--------------------------------------------------------------------------1--------------------------------------------1--2122------12213113211211122122122114344364411--111----1----53-----2-----11222222221--1111----11111----------------------1-212133352112111233322243333-33133455113321321141213211--41231456555511-444------------------------112221---------------1-----------112232421245445444344456335543572--211421122234332345444544455-445544444544444544443335334333333333433333344433344313333333333332221---------1-122111111-1111-11-67657322224433434334444543333---------15454333334343334334331221111--1-331111--------1-------------------------------------231- 3323567-OAB266FGIH9KKJFQTRKAADBABDFCDBBA8EBBDCGDGMPRVQKOMFBEFGDA76AA3A7688AAB38B7GIGDM898GNBI9D9C7A77AEG9F27WFLAG8ACF8898BC9JGCHDX*C-JEJ6CC8DC9A77BB85E86TC98AC5EK5B9B7FABJ798A9B88zC967AKPhSFRIGCFHFGE * c.25.1.1 Reductases
[ 360] 332-13366666466935751328E98B79C841524-483524368924E8B-A2537-24422-5A 4785M54B879443E54AA-AH3298A9AAA6NAGD9FGI36776E9B5525I8J54711B9A3E7F8GI6222224322325--321211211221--18245444532333333222322323535776432455566111A75545234533332322323366762121111121111443443323445555567847868997632256595542443322322DB434353323333332257663233443321344333454123222222232222332222222222322222222222225222222224369385552432233433334445242454624B883A262344226334C24776813222456656345556244454446546-447465537C818558AA89BA88465545664535247333333337333435511111111111111111111111111112-2345246746677886566558896677648B56578622554243885573335436232452111123252437234225573635431447345454767556242112222222212111111124121342323213413211113221511722235121-124651--11112112211442121311-2111122211212222122553232112211111132221212421134223-411111111111--12111112111236121111111111-11112223311211415647468445433234422333432231223343347421265236332454444-1423334331112121111411121-121222222222322133244512412321713 ------------11-----1-111-11---11111---------------------1-----1--------------11---------1-21-111------12-2----422212612111332124-8H4-3342112312222232222-612322112111312211--31--1---------11---------- * a.4.5.11 Helicase DNA-binding domain
[ 361] -----------------------------1-------------------------------------- ---------------------------------------------------------------------------1----------------------------1-----------1-------------------------------------------------111----------------11------------------------------------1---------------------------------------------------111------------------------------------------------------------------------------------------------1-------------------------------------------------------------1---1-------------------------------------1------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------1-----------------------------------------------------1----1-------------------------------------------------1-1-----------------------11--------------------------------------------1--------------------------------------------------------------------------11-- ----------1----1-11-1------------11-------------1--1--22---11-2--------1--1------------------1--------1-----2--a*lI*TaTbbinQ**X*Z**l-***SSUadWD*zEQtUs*WJjTOMKe---1-111----1--11-2-1---12-112-11---12-- * d.19.1.1 MHC antigen-recognition domain
[ 362] -----------------1-----11--------1-----1-------------1-111---------- 1-1----------1-----------1----------12-------1---------1-----------1------------------------------------1---------------------------1------------------1----1-------------------------1-------1-2------1------------------------------1--------------------------------------------------------------------11--111111111--------------1-------------------------2----111-----------11-----------1-----------------------------1---------------1-----------4-----22222222----1------------------------1-----1----1------6--1---1------------1--2---1-------------------1----11--------------1-----4---------------------2---------------------------------1--1-1-------3-----1----11----1-----------------------------------------------------------------1----------------------1-1---------2-2-3-1------------------------1--------1------2-----------1--1-------------1--1-1-2------------------------------------------------------------------- 465576M-cHD576847758797677877787767587675778778666667777866666965555-555655553655745658786B579695554676C9C2KbEsmmhjjoUSPSWVRuiSvQ**fIrZ*UPURfNVcUUUSSSfRUtQhYUTKbjHdPPFPGGYCDZK4DBA*86588E8FH5BF98abUWJ * d.148.1.1 Hect, E3 ligase catalytic domain
[ 363] --1-1------------1-----11--111111-11112222422112223321---11-21111-1- 2331732334342253222-2222262222225333553322233232333443421422435363586621222222123324432244454434-113423453624-111111-------1232222324323223311162424333A4333335434463333443433434443335443222222333333333433333334654333422333332222225334444444444444434433221232321212222321233432221111111222433333333331111111111111222222222324234666445424365223333322113443255232323233243124346433354444433353343445544444544444-443444446A536777548444665466344644452453333333334442464-1-11111----1111111111111----2668633544234445533332334344442445424341222422433324424323322253333333346443436642245443666256545444433335424453444444554535334344455433775544644664444454445544534433-11443311111154553434444444444-444444444444444444654544556556655655556566563334444415443544344541134232224444444362222222222222243338324563445566674667775566743433533344448555556756633444444443333224222222211111111211-------------------------54633222323453 111-345-3112113243-1353536412112221234446441226212233521112212123243122121233-3122223213436242111221111254-457E47C7482434244BF3G5Ic62838333263474343435256254688A83H5318582639E3553T22236789B3855487886 * c.1.6.1 Alanine racemase-like, N-terminal domain
[ 364] 113-111122222121213222224112121221211111112331312288711211222---1--3 2231221344312122211-121142111112635357341424434412227251211133532134531233322213143222222221-122---2314324332--------------1231231132311112221222A52411111112123211112134---------1---132112215363333334323333332322243333544243444444463333333333333333332221212311111331144-1-131333222111131122222222222222222222322222322222231224533334332321311223212211311311123111211111111232142261111125456316325231222-222226-554454635432433246333233453137-33133-21333333334333385211111111--1111111111111111111-54482-11-232222231111334322221313C2334124B234143432333223332221--11112-3123322331221131222-4333225334443344232331222221-1-------21222554324B2375332222234232282223842--24122------22112222221222222-222212222222222222243322--22222222222222222322222222-333332333333---32222233332632211121311--121235455643-223133351433233466112122222222522252223233333543444433311111141222222111111111-1-----------------1-------22222212221111 1222573-844255677A978876797667778665787888977798778AA9689779996554443546564776764655465346D4766B6775556A7916M9KAH9CFF999BB9AHF9G9ZxE-HEM79ABH8AB989BB9B99HAFGCE9D8EAC67J689CKC54532G23336D9CJ9F956EA8C3 * f.59.1.1 Cation efflux protein transmembrane domain-like
[ 365] --------------1-11-----22321112122111-11111---12--1-1122211111------ -1121---------23333-34113433333355352221-442-1-21--1111-1---21--1-411-3----1----1111-1--3433-2---------133212--------------421-2211----111-1----12422212111122222133-34347121111121112-1------11-444344542434433-1--2-444-111--------1-1--------------------1--------------1-------------------------------------------------------1---2222222252--111----2---111-1-11---1--21----2---23112------1622-2114312------------22-231-1-------3131232-1-----2----1----212222221-----21------------------------------13-21111112222221222211-222222112-1111----11----2432-1-1----------------11----11--2---1211-----1----1221411-1-----1-----11------1111-1---1-11------1221111-23212--31-------2------211-11-----11111---1-11--121-21---1--112-----1----1------1----11-11-2---11111111211-----------1--12-----1---------------1---1-1-11111112111-1-2-2-----------1-21-12------211315112111-1--31111111----------1---------1111------1-----1--111-311---- C*11GBE2I365869BECBB9AADCEEBA999ACC99858887989ACB8FCFDBBBD8D9A88798926A78759928888888AACBCMJEKAG967396799E4Cb6lBG9IMJDIAACHDYRBVF**LAQKZACD9HCEED9EBACIAAPFKFFCCCC8LDOBHCEHGEJ25HEB*K8IC9QQMjBbaCAEHGGF * d.92.1.7 Clostridium neurotoxins, catalytic domain
[ 366] -----------------1-------------------------------2---------------1-- -1----------------------------------------------------------------------------------1--1---------------------------------------------------------------------------------------------------1------------------------------1-------------------------------------------------------------------------------------------------------1--------1----------11--------1-11-------------------------------------------------------------------------------------------1-------------------------1----11------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------1--------------------------1-----------1---1---1------------------------------1---------------------------------1---------1--------1-----------------------------------------------------1------------------11---------------------1----------11--1----------------- 2--1A7H----2324----1-11---------------------------------1-1------12--------11-211--11-111-----21---111-1---H43m**w***bieYajj**X*W***F*y*abga*XiyhWhfbX*YT*awijhIYzYQQJIeGLdMYOF-2329111112254133--2232- * b.55.1.5 Third domain of FERM
[ 367] 33353545544454536333333466668454223444444444444436997843444442226243 2271311111112133333-351134333333433333341111412112211221121143212244321111131111214-11111212-31-----3-2365416-111111-21----321-212221-1122342225123332222211232222222122222121323121134222232-23243435444344555444334364423231432222223522222222222222222222443244234443322443332222222222222222222222222222222222222222222222222245215444443444432442121442121333444334353233433311513433411111346574323443511111111112-334254343431233223332333341223242232222111111113112225211111111111121111211112211111223341-113131121351-1122341111-21242435-12541335461233-22223323--------1133322767244344344223323453653343B615121111211111111111112122411--7551123212121133432212234242--1-212------21241111113131321-111212112114111111311221--13122232143222223311-1111--221112222212---2-----234422324---111---1---1-22222-1--13222233122333354333---------1333422222-152222232321111111--31--------------1-322222-2222222222222222222-2---111112731 7525768-G443879668586767957775655655783446789777495786565675554353441445536452444444544546766548656555576648CDMBEADBF9897AB7LG8I8b*C3BBP89A7D9BHBA9A75C66J69D888D99C9B8886975BC39B4m6766799AQ8DI5577695 * d.157.1.10 beta-CASP RNA-metabolising hydrolases
[ 368] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2133CE5-F56--17B7H63-1113133345442314635546233A76655452667448621111--11---211-11-222-1---7U97FMA--11--1A95-6*i******gdZTTXkY**N*f***6ty*UcRQpXmseIkXULnWL*koehpFEIWaZbCSJDVZ**81LD22---23QHJU8M93B13335 * d.42.1.2 Tetramerization domain of potassium channels
[ 369] ---------------------------------------------------1-----1---------- -----------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------1-----------------1-11-111111-1-----------------------------------1-----1---1-----------------------------------------------------------------------------1-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1--------------------------------------1-------------------------------------------------------------------------1----------------------1---------------------------------------1-11---1---------------------------------------------------------------------------- 746AAAE-XD5179A56678888999A66554577666566555554667877678576555A766465585655664666555466668H86B8845665CAHFI-G*DXomfkgcSNJNPRR*oMiR**d8sa*MNTQhQReQMSRLKaOFvRTPPPJCNEVGulpvyeGPIO5JE9pDCBCETUao6hIZJEBCBK * c.13.1.1 CRAL/TRIO domain
[ 370] 44295389AAAA9A997366755ABAAB88AC121121111114414153445-BDBADBC63592CF -212G--22231--84534-37--6D34344676767JQW463575231331DAC348--CC92D6GGGF53222-11-2223-2312223213111--2435462627---------------111111111112222222222---1----------------1----------------55311---1145555556445454664644474551123122------76-----------------1-1---1--11---1111--1----------------------------------------------------12148222212222221442222211---224344333312141111---4--C8891112153A9C33356583ABBAABBABBG-22822B269N2-KDDDGGYJKLHG93743AALBCABCJM222222224664178A------------------------------1EM65EDCBHQLNNQOGDCCBHHHGGFGGAFLLHCEEE-188D9ABDEA7C6C23374---622222212---545-262434223522223-1---1--11112132--------------------2--1211554351A3A825455434633335465334--1----------34673343333333333-3333333333333333333657464444345444454354555933333332-644444444444---3-----2212-1B4F222242233342222AB99A7713132CCDCBG8E6DICA79AA---------2445655554A8B874433333333------1--------------------------------------------------1--1313 -------------------111--11-1111-1111-----1-1111-1------------------------------------------------------------------------------------------------------------------2------1--1-----------1--7---------- * d.58.4.2 Lrp/AsnC-like transcriptional regulator C-terminal domain
[ 371] 11112222112111221311211322233133--1-11-----43-13-1232111111114431--- 254-C12222323166511-14--48111112767623942B274132123-41312311314252649E2----111212131-11111----11---22-1-3121---------------11112112212122223---62131411144--1-12--1---66512222222222122211111-2-7A9B9BC98489BAB9233337A883224443222221461333333333333333111222213312111222222512-126752223111323222222222221111111121111222111---1-2456333222222323331121112121-2111232121413231-1--32522211112173G9B12321-4122222222216-988965982B31D9977789A9BBA43212451111315222222221342-32511--------------------------1--29-39CA56BBBCCB533337888554528B5A99FB-1445356338444I7-42-3538411111111-2142144-113--23221-67314551333238D553112212222212-------121133354-111333233222221133212212113---2323------77743745556587754-5565767555575665664999654446766666666666667B534554521622222222222-----211233331-645---------------877781522561DCEE99B87B8C94987144435434---1323223531348613133---1111--1411--11-111--1--1-----1---1-2------21--1---211222223237-2 11-18A5-C5312267BE78BABBD878955456766555655455A98C569857645523112111111143111111211131111A74B8523442321916-2a6A223221311113676352IcA-44B3222613231212221244232333356442643545342644h342A3556EC9486B5787 * c.33.1.3 Isochorismatase-like hydrolases
[ 372] 11-----11---1-1------11------1-1---1-1-111----2--11----11-11--1----1 --1---1-------------------------1111-2---------------------------1--1-1--------------3----------------2-11-1-21--1-1--132331---------11-------1--11----3------1----1-122-5--------------1-------1222332-5-2-21-12222321321122--1--1--121----1----2----1-1-3-1--1--11211--11---1---------1--1----111---------2221--1121122--------1-21-2---1111-----1111122------1-132-121----1111112-12-----2-11--1-1--1----2-----------------------2-11-----1-------------11---------------1-1-----------12--111--1----11--1-----------------------------------31-1-----1--11--11-1-------1--------------11--1113--1221-------2---1-----2-21--2212412-2-11-111112111-1-111---1-1--1-1-1---11-21122--3-11------------1---------------2--1-1---------1------1-1----1--21--1---1----------------------1-3--1--2122--1----1--1-11-1-11-3221221---------1---1313211-----------2---111-1112-2221-----111--------1-3333-----1---12-2----1--11-----1-----11--11-31-2-12--- 66325DC-L9E8BBD635B24645234117756338922231344456344577134127645543343631612342335231624544823267344-33245A264EuXWXWseMTJMMgO**N*P**t8*h*XPLUiJcoXJYRNOqPL*PfXXkIIIHLG9DLCIRDPJA3423F34532*BAC4HB4CFLII2 * a.114.1.1 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
[ 373] -------------------------------1------------------------------------ ------------1------------------------1------1--------1-----------2---------1--1----------------1------1-1----------------------------1--------1-------1---------------111--------------------1--------------------1------------------1-------------------11-----------11-----------1------------------------------------1------------1-----------2-----1----1--1----1----1------------2---------2-111---------------1-----------1----------------1----1------------------1------------------------1----------1-----1--------1--------1---------1---------------------------1----------1----1--1-------------------------------1--------------------------11----1------1------------------1------------------11----1-----1-1-1-------1----1--------------------------------------1------------------1----------------111122------1-------1-----------------------------1------1--11--------------------------------------------------------1---11--- ----CD9-549399CD9A89AABC79D989A8BBBBADBCCDEBDD98ABA8C9889B9BCB7887763966769654686798689984D4979B7566587HHD-G32Wx*lwuZYVRRYbX**W*S**qE*g*NWSWpTasVNbWUPoOK*VgTaYFSYGGF99KDFS8NHD2334D7551-6558C84123B98- * a.238.1.1 BAR domain
[ 374] ------------------1-------------------------------------------11---- 48e1311111111121122-21111121222111111113212122121--1111213--11-12122111------------27C8B-----2---11-3656C9R2A---------------7347543253435564---34425333122332224222322123313--1112----46345----433333333343333332344433334352322------4-3---------------11-----1--1---------1---------------------------------------------------------------------------------2--2-11-1----1--------8-bB88A111115CNNEF6B99A975555555555817EA8DIBGA83-B773C9AD99JFAI744I7AB9CAE5IBBBBBBBB76754B751111111111111122111111111111112CH537A97GKMMKLH86666ONPKEEDD8DNJQIIGU5BBBCRE8ECHHEHO9E7BC9B9843332232B8BA9N6-12--211--334-A7A46662-66769J--85695556555332344344A6-8D4464-67985867788885C85536779B699---942A-------1-----------------------------------111---------------------C---------311111111111---6-----222286A------1---------1-------4948BKJLJECIIEHGFDD523---------44777555558BB674222432222----43E-662211----------------------------------------------5B-4 53--111-631-11111112111-1-222122211111111221113211111111111211-1-1111112111222221111111-113111121111111-11-19162341311132--113-925J1-452-11332-4312-2-113213124213122222136122124-1D11121523D1233231214 * a.3.1.1 monodomain cytochrome c
[ 375] --12212232223222-122222211112321-1-111221222--1---21111211211-1----1 33538312222-1147866-854459656664677747EB32447463436479A456--536633658524555433211241----1113-3121--1333347452--------------1341343233331--33---222432455112221223222233334123133231122112552212144444445434445433354344453333511233323253887777577778771222232246632222226634132622313-11111131-12-31111111-------1-----211331111-3--21333334413-2344----32211422-2442121132222121-1316322211-11236443132233224332323223-23425244593-633667C85668325333543434343222222224314-23611---11-----11121111-1111----232541-44475885744333344633343239354E951323532233344467434112-22443332332262322534343224334231332313-4233341121---1111-11-111111142123-1755665524454533345443334246345---2124------22452332333234333-3222224342324222223553332222222222222232222532333322-422222222222--133333434444162633332212222333231213121112232331231213243-21-22-13-12135363333335433631-2--1111121--31222322-----1---11------1---1-----1111-1---112--2-2113411 2133371-9421453957476736467332212332532364345278396ABEA98762221-2111134124441132433446-1257454346565424116-4H4CDECECA6576664EF5K7O*A-C9J6436C67A624863764D4B7A949B3775A847A43843454*43664BACE35A8AFEFBB * c.2.1.4 Formate/glycerate dehydrogenases, NAD-domain
[ 376] -------1--------1----1---11-------------------1---11--------------11 111-2--1------1----------2------12221232-2-141------121-12----2---1122----------------------------------1-1--------------------------1-----1-------------------------2-----------------------1-----------------1-1-------2-1------------------------------------------------------------------------------------------------------------------1----------------------------------------1-------------1--1--11---------------------1--------1---------------------------------------------------------------11---------------1--------11------1-----1--------------2---1--------------------1--1-------------------11111---------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------11111------------------------------------------------------------------- 3346664-L94395CCCLEGDFH8FDFDC8C8AFFFCJFKDFDBCA9BNMRJbHHPGCBHJKD8B6675565987686896777666556kIC9E8A8A828C88A1E85YggYYtUQNaLOaP*jIuT**jBob*OSOKkPYdNHXULIcLL*NTQPaBGLELI8EaIiQFJC52343T6654499AFHc5479BGA4 * g.44.1.5 Zf-UBP
[ 377] -------------------------------------------------------------------- ---------------------------------------------------------------------------------1------------------11---1-----------------1-------------------2--1-11----------------1--------1------------------------------------------------2-2-1----------------------------------11------------1-------------------------------------------------------1---------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ C655EAR-xPQIHIF43442232322233321221314333334233222243331142232353243-431135232222581523235A337723435253567-RKc*XicWZcLRUVapZ*pPpP**g4jc*RSXUcRVbPLVNLSdMMkPbVYcXjSP*YIGfdjnBJiW3HFM*877C5PKJh3PI19ORKPK * c.10.2.4 U2A'-like
[ 378] -------------------------------------------------------------------- ----2---------13311-11--3111111211111-31-322-----------------------111------------------1----1-----------------------------------------1111----1-2-121--11----1-----3----1-------1-----------------------------------------------111----------------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------1----------------------------------------------------------------------------------------------------------------1-------------------------------------1------------1---------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------ 1122bhB-E64177DEHIHQQYVbchhFFCDGFG9BDD9D9DEDEDKFHIWTkaNSEE9ABB98E9A6-AA6CDFHG2GHIEBBJN244GJAHACGEEG6CACJJI3PWL9A89AC755555A59E775JnA-955555455568254415527567647EP8FAFFdIH*BB718UKE*BDBOWuwz*H**FB****T * a.120.1.1 gene 59 helicase assembly protein
[ 379] 1112214433333253222212-321133274-----1-----111121-11111212-225215-12 36C-944533522253333-7311493333343333499926134353322-565836--543174956531111111223361-1--1111-1112--1312842444-------11111111-11------113445411135133222211131121121211--1311111111111173533113225778789675888988G8445598836A9C45555553G96777676777777779989533132232242553363121334223222222333333333333333222222222222244443334451813456455643552F1155642715153-1-2212111913--23-5-C-3444611111219DA3327668211111111116-33843743372-A55332455573443423764545577111111116664-1--11-1-111---1111111111111111-1245751387356886A75444366465554349458A791257511712B392C713--11-141-11111----142311312311--13-22111124222223514-421122122211111-111--122224123224354422112-16211-4-43-34--3111121-11122F53324442422244-44445234344244444435553513321222222222212224332222421----1-------1--4222221222114322312113222222133331311131216646545727876274411---21-12122611111434333122222122122211-4111111---1--112-11-4-1--11--------11------22222122211413 ----684-E83113566649755A8B833332313343133231113446B7F757556555746476243373553244444464222AG667968787653664-224I7C6676323454595262DU5-585-33374583245235238555586451B533321335663651V---3777AC5632324346 * d.58.19.1 Bacterial exopeptidase dimerisation domain
[ 380] ----1-31111111111-12222-1-------121--------1-1-1--2--1-------2----11 122-2-------------------1-----------1----121-------------------11--121---------1---1------------------1--------------------1-----------33234---5-21111121--------112-23231----------1----11----------------------1---2---------------------------------1----2-1----1----------11---111----------------------------------------------11-111--11---1---------1---1--------1-------------1------------1----1-------------------------1-----------------1-11211111------------1-11-----1-------------------------------1---11----1--------------1---1511--11-------------1-1------------------14----1---------1--1--1------2-2---------------------------------12-1111111-11111-1111-13---1------------------------------------------------------------------------------------------------------------2----------------------------------------------------------111111111-----1-1----1111--2---------------1----------------------------------------- 322233A-XFC19BC5676598A7657886747675574763678877886475266685464344433544434442245555547462566B594668456ABB15j2hfiZbetQScKRXU*yN*K**k2xk*VQNEiKWVcKVPTOgNRyMOQXT7A5ADISAoHKa9KJ8155Hk396C9Qdz*5gT4CKqUaH * g.41.11.1 Ran binding protein zinc finger-like
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c.26.1.3 Adenylyltransferase
[ 382] 22211133333333333233333332222332323344434342222212222322211112223222 3351521222222231111-1111111111111111222222211112211122222211222122333321111111121232222222221211111221222223211111111111111111111122113333221112311111111111111111111111111111111111112222222211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111123223333333323212222233222232221233223223312222313132222232222222121123233222222222222133333333223-2222222222433312222222322321111111111122322222222221122111111111111122221111223332244444444444444344443445333432333332233332333223232334334333323323312322231231112243333444233434223211111111111111111112211222333434323323333323333333334333211232211122233332434444444444-44444444444444444444443334444444444444444444444444431334334534333221322222222232332344333233322223331333322233333334323434432221221122122333333333333334422222222222222212212221111111121111111-111111111111111111111111111112111 45337661ID8598776466666676666556655555556556666666666665556666566565356554666366466664777686656645446557CG38AGS9FBCD955C65F47F6K6N*6-DFF4B73e46DB47753A43C6B6688HN69789H948EA978567t55657ICZM6C87789687 * b.44.1.1 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
[ 383] 1111111111112111111111111--22------1-------11--1--213-----11111-1-1- -12-2-1------------------------------1-1-1--1----11-------------1--2111-------1-1----1111111-2111--11---2111------------------1----1--1----1---11---1112--111-1-1----133---1-----1----112-----112222222231333223-1111232311112--11111243-111111111111113111-21--11---------111-----1-1111----1--11111111111--------------11---111--1-1------111---1111----211-1-1----111----------21-121222-----2133221321112----------2-11112211111-322223-4331-12312-111111-----------211-1333------------------1-----------1242-33322222223222222245333323353123112322231221221212112111211111111111222--11------------------1211112311-----1111---1--------1111211122321221212222111111111111111--221211-11122221213553323533-6243333333633444344232111113232333333343323131111111121111111111111111111111112142211111211111111121111111111222232222243331121111111111211111111111112121111111111111111----1--------------------------------------1-11-1111-21- 988887E1wQOF7786889A9AAABBAABBA7BBABBB7CABBA8AA999999B889BBBAAB9AA9A69B99AACC9DDAAAAB99AA9E889AAB998689JGM57V9POcINKJDCDCBFDJI9UAm*K-QFdBDABL9FFDBCCAAEC9OCEHEEEHLEAA97R89DUrB85A99*877A9NFSc8WDBDHFDGN * d.159.1.3 Protein serine/threonine phosphatase
[ 384] 11--1111222222211522222111131111-------1---1------11---1-----111--11 2461532111111175544-47114C4544537B9C47C936393342143278943574324132B677221112111---4221--1111-1------2--121312111111111111111112111111-143333---244321443212233323432123252222211121221232121114234454544435544454344354543333433455444422111111111221111111131324412111331144323343323-------11111111111111-------------221---1111-2-12-------2-1-1---11--1---112--331---11-1332----3133223-----52AC94444745322342444335-34A34C3C57218776777A898978222445333365822222222A2233111---------1----11-------------32243-3953A8AAA988333188CE777737C8I9A86-4553343336388892332312342222222232223-22--331121--2-2-2142212222222-11------------1111-11-----22212341323453333334333333333333121211311111133221225445565655-4555555535454455553555552215355545555545455243233442-122222222222111-1111-21112436422241311212222233333241123167674654454453434-111--1-11423322222444332243333333------2---112211111111112--------1-------1-3--------2--11111431- 31--222-8322433D8A99989CC8A6555665665444544343673449EC55555776222111-231212232321322231114738462776543344513E78BB9IAD67666A7II8G5P*B3HCE7655C479747725C35E6977A334854534FE723526673Y35434C9FM9F75586669 * a.100.1.1 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
[ 385] -------------------------------------------------------------------- --1--------------------------------------2------------1-----1-1------------------211------12----------------------------------2461112------------K57-217--223--316-4--48DQ1--1-2---2------------------11--211-22------2-3----------------1----------11-112--1---21------1--------2---1-1--858----22--12211-1-11-2131---1------------------------1-1----1----1--------------------------3116-----1141-1----131----------1-447665512----11259935324-----3264144537-------------4---------------------------1--2--23-----1-2---2---------1---------211-----61-------322--5---912--41326---1--------211-4--1--2----2-3----11----1-3---------------1--1----121-21--11-11116-21-111-12113---1------------3----321-12----3-----1---3-----------11115----------------2---------311111111111--71-----2112--6-1214---------2----15----147-1111221-11121-1A4---------------111163-----1-------1121--2----------1--1-------------1----------------------------- 21----3-4-------------------------------------1------------------------------------------------1-1-------1-1-1*******TRXVadT**L*Q***3*y*SQTNrQjkWCcOKK*JL*c*WplKY*QE98CF55bMWM3---------11-1----1---1-- * b.80.7.1 Serralysin-like metalloprotease, C-terminal domain
[ 386] 11121-11111111111222222122222222111121111112222211332111111111121111 2221333233332332222-222234222222222233572325222333333333223333233332333233322232211211-1222222222-122222222222222222122332322-11121212233213333212162221222211211122212222221222222222111--111123333333333333353323333333222522222222233322222222222222222333122222221222222222222211123223222222222222222232332322222222222222222233334444455353333333333331133321221332222333332---21222111111211211112111122222222222-22222211221-222211212222112222222222222222222222222221211222222--111111-1111111221222121112111222222222222224422222222222222232321222122212232223122222222222322222222-1-121222-232233323---12-33------------------------1115232232222222222332222222232223--232233-33332433333333333333-3343333333333333333333334333233333333333334333333333143333333333333323333343433234233333333333333422222222213444344445344433445111112111244533333333333223222222222222221------222121111121-11--11--1--1112--21-11----111-1111122 5445675-F6836665A978899CBCAA998AB878ABCBAAB77799CE9888986888887876667677766885887666756676A6A6667557557BA65595F79765AA6788B8CB7H7X*G1FBE87A8E5AC777788E68L8D88C57555586855A56755566w54555AAAD8E95567665 * a.80.1.1 DNA polymerase III clamp loader subunits, C-terminal domain
[ 387] --------------------------------------------------1----------------- ------------1----11-1-----11111---------13---------2221-----G71--1----------------------11----------22---71--------------------------2-72223---1-2----------------------------------------1------11111----1------------1--------------6-------------------------------------------------------------------------------------------4--1------1-----4------2-111----1-3---1-------3---2------------------1---------------------1------------------------------------------------------------------------------------------------1-------1-------2---------------1--1--1-1---1--------------1DA-------11----3-11133--1-1148--------------1-----------3-------1------111----111--1---------3--------------1--------------------------------------------------------------------------------1-1-21121----------------------------1--4------1----------111111111-----------------------------------1111-----------------------------------------------3-- ED99SRC-UA9-88856875446554444455554534443444346756856955A668676567863678756652746656573456F7678687766696891C**pSVRUSPOLQKLMSugLaL**X7bL*PKNLYIPXMKPNTLSKKiKSOLNJQEFOOEGLHNbEEWO5LPK*ECCHCXNOc6URCQJgOQU * b.69.5.1 Regulator of chromosome condensation RCC1
[ 388] --------------------------------------------------------------1----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------111------------------------------------------------------------------------------1------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3255GN4-31139BX3488P355443386EA894454555676655IN769DDX9ACS8A9812-222-22222232222222222CAA*7A488I967T6A1BH*2B*AGqYXggTOPPQLVP*vKpO**f3mc*MSOKaMQgOFTPIKXIIeMVMPS69D87AeFL9EH6II51985I2-3G6IJHM8AB46****- * b.34.13.2 Chromo domain
[ 389] 22-2--6B99A99977-222243F7334113611---------------------------3442-22 3553D2-5--134375544-433348444444553567DD368933352422434546--66A-A6BEFC4-----1111-17---------1-11----343363553------------------------2-22222---412--2-------------------1-------------55422---4233333333443343333533433334554432------64122222222222222311-3--1----2-----11---1-------1112---------------------------------------3-1122111112112211222111-1-316113-971517-251--1--1-8-18773-----559775335555757775575777-33933B47C85-6443446444667A33456G666656C--------6---157311121222-----2---12--1--1----233C3-5EB5BBB9BBB77999CC9999998AFAK7D9C2388687988A99ACA114----24-------111C763B57-1---------54514-31-55558614---------------------------44-652447544444444444446444446---43--------5444-446445655476-466644474644444644677744544444444444444444492444444--444444444444---4222224444-4734222--------2---99959566648-BBB96A957868A82231111111111444444444444443333333334------21111111--------1----------------------------------------6 ----116-F76-2233432533469561111111111222222212122565562122254411--------1---------11-----12141113222222222-7A8HB96788666669964686Dk6-7895355666B556664666A5475CAFG3D7469493EG743362Y2223377HB2555573336 * a.100.1.3 HCDH C-domain-like
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e.10.1.1 Prokaryotic type I DNA topoisomerase
[ 391] ------------------------2--1-3------------11------------------------ 1-1-*------------11-1---1-111111-----1---7-1--1-3---111--6--44--U-2CHE1-----11--1-------1-2---------4---D-1---------------------1---------11--14111----1---------1---11212------------1------------------------1--11---1----3----------4-----------------------------1---------------------------------------------------------------7-222---222-3-------1-2-------12---------------1-11---2-----1-1-------1-1111111111--1-212---1----11-1--------1-------------------------------------------------------------1-1-----1----124444--11444432--1--------------11--11------131----------1---------------1-------1-----129-----4-2222-2-2--------------22---A------1323---2222----2-1---1-----------------------21--------1--1-11---------111--1311111111111111---1-------------------------------1-B--111---3----4--------------6-----------11-3-2--------------1111-1--11--------------------------------1--------1-----------------------------1-- 4357H6S-821-3344-3323225473-12---21112112121115379565412353332-242112112223-3211211-22132ER7-eIX859M32-SSd77C5*qrcccYQNOTPVPtfPsO**l6pctQRKKjNWdQIUMPJdLLsOaWTYROUWkNtCWGLQGKLA24D2P121-16BEQ2DG84DLObG * b.42.2.1 Ricin B-like
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q5347568AA4796698659 * c.51.1.1 Anticodon-binding domain of Class II aaRS
[ 393] 11----2-2121232---222---4221--22--------1---1--21---1-------2211---- 3243621111112234522-222253222222433336644557343322224553351156416494534--------11151-121222111112123534454445222222233333333-1-111112416552211125121122112332312212213223132223223222135333221524444444443554444564444444555333232222256333333333333333344442-1-3211---221112111111222111111122211111-111111111111111111211111111133123111111111223111112112--4111-2121-1111132314226-3622533433444344344334366665565565-442443444532444343854475455245373333535444444443442334422222222221122222222222222222247E53232334444545333344473333154444442223332311131365223331112311111111222532-31211-1221111324266632333333-511111------1211111111-2223343-3313442544333453333343343461-133121111113222-232223233322-222223222223222222223322342222222222222222322222222223222222222221223343333333134232222221----222222222132216255553433344422321122222222-22253233243243443333333322221131233322--------11111111-1-12121111122112-----111-11112414 33--546-E451556364546677866334333344334343354455447565643533534522322242322221222223241124876556334743376946C7GFBCB895655995EI7H5Q*72IDP6656A87B769746B57A3GA569HM56796MB8G89C47645*45457C9HE5EFE699868 * c.36.1.11 Branched-chain alpha-keto acid dehydrogenase PP module
[ 394] --141-3323333434-63333332--21232445444455544454466765333222123-13-23 2353423322213165544-442257444445755577CH35481221322243222211547245736521111222-23274445344473411-11-313332343---------------454575555556558644455234333233222111112223545311111111111123345331433333333433433333443343343434441122222284133333323333333222222-1-22-----11--22111111121---2-11122-----------2222222222122111111111166255222223243354551---514113346567656531574457112-442222--1-1355442225444544344444345-11511312333-633533444444452334556555444111111113222164711---------------------------21561248865766877711114478444434B6979C81267484465778475335332322111111111147917933555355555-656554446665636465222222223113-------2322333334343325433333333443333253345-1-2232-11--111313212331211122-32-2222222312222222664321314143434444433334411111121-11111111111111-3111113333345472222221111-12223322312222A344444444553767344112--11-1322242333334243222222222211112252443444---------1---------------------1----11411323333431 ----236-1-21346898467759687444444444554444444374467786556555444555543564645766665456653344C694744444454876-3937765B64334323284354LUA-67B2335433423344442263424535737345J42B33933353R2323455676986573548 * c.1.10.5 HMGL-like
[ 395] 222222--------111111111211112111221222222222314411434-222222211114-- 3341433333332333433-3411443333324444433334443223333332333322334343355533333433111233344533332333311333333332322222222222222332232222333656772225522212222222321222222222321211111221114445544344444444444444444445444444475433432222225711111111111111111111221222222222222322212212222222222222122222222222222222222222322222222247677666666656554556666365336336565776885564443334551333533333344343333333323332323333-33333343334423333333333333324333333333333333333333335343323333322332233234222222313313343344434333333333333343333334343333322333333343457333345444333333333554543579565965777775777567677355447664333333333333533433333333344452544444455555655555555555552-3444411111144444444444444445-44444444444444444444444444444444444444353444442334331444444444444114322233333354545444444344434444444343444453555555555556554553222232225555555565555752233333333333311433333443333343433211111-111111111111111111153333444442113 11--221-2---22222222222223233222222222222222222222322222222323222222121122211-2121222211123222241112232446-24152222533121232542234W3-523132222333122212216123123741624131142D222232Z3223255762692263331 * d.14.1.10 ATP-dependent protease Lon (La), catalytic domain
[ 396] 1112111111111112111111122111112111111-222223321311111113111221112111 3232522222221222244-4222434444433333232215521123111-1121-1--421211111221---211121311111122331122---1522132213---------------1111111211111111---2233442221111112111121144331111111111111211111-1246666655775775762244336764223-2211111282422222222222222333332------1--111-1------1--11---12-----1111-----------------------213----443222222222121223322223231222221322373-2423214121121211111211122212212221111111111111-12213241132-11122142312111121213212132211111111131311111111111111----------------1--13111122222211112222222222222223143223512433222213434254332332222222222213523115122632223331353244553346377322212222222222223222324222223335332232233333334634433343431-12222------33462333333333333-3334333333333333333354334534433333333333333322333331-333353333363---411111332211422434222222233332222222232242323222352222222332-1--11--23333433533433322323222232222113-22------------1----------------------------111--1---1221 B977BB6-V9C5676666666676666767676666656776666667666676656766666777874786677986897888777876C7677767767C878757IHECB9DBD67A8897HD7G9W*B-98G8949AA89A799789C7D7A99A7A6CBD87758I9CB8799A*87788DCEJ8D9BEC9ABE * c.111.1.1 Molybdenum cofactor biosynthesis protein MoeB
[ 397] ------------------1-------------1----------------------------------- ----------------------------------------------------------------------------------------------------1---1------------------1----1----------------------------------1--------------------------------------------1-----------1----------------------------------------------------------------------------------------------------------------------------------1-------1--------1------------------------------------------------------------------1----------------------------11---11----------------------------------------------------------------------1--1----------------------------1------1----------------------------------------------------------------1-----------------------------------------------1----------------------------------------------------------------------1111-----111---11111----------------------------------------------------------------112-------------------------------------------------------1-111---1 ----UWF-1---D8H355596557778555555545555555555555666665447555454554454477555545555655552227B95C673233346ILX1U1SRxtgyooSVU*VpX**R*U**m7*k*SRXksQXdeMWVPOmkN*VZRaVAGOHFHDBYEHVAIKB------------1-4----4444- * a.117.1.1 Ras GEF
[ 398] 11-2--2222222222-2222222311222243223322222222222323332221-1-13112-22 4453211111111244422-211123222221133333642113331-222212111211221-24521122222222-241422121223212---11-211133231--------------211111112121333432225332332232322222222132322322222333232233533322142322222222322223343333322232433112222223212222222222222222232-------2---11-------12-221-------222-1112111111-------------222222222-23-22111111121233221---2-22-422223322322-222222--3324222212112328552244344322222222222-4554455433314333236635332222232363563113333333365523322111121111111111111111111111112242224543445554433333554533331333845532222554454444774334232212111111122223322332222222222-111111132232234231111111111-1111111111211122333221312312222222222222222222-1-2532-11--133332334445454333-4433432343433443443344222423222222232222223333322241-233333333333111122221333326332111113-111-2112444441212111443433242232324441-1--1---211121111111111222222222233332211223333-----------------------1-------------22--2-222212- 22--445-93214468A7A9BC8ACBB7886887987787677656667AB8AA7877667565777646A6776775667777773566ABA85886855588A9-838GBK77HF76857C6B87C6f*B2I9N5768F699D57876976CA68797BA9A788K79G89D74592H32455GDII7I74354644 * c.77.1.1 Dimeric isocitrate & isopropylmalate dehydrogenases
[ 399] 22313343444444444422222-21121312223222222221111122111223222213222-33 3724821222311121111-12112611111154441123442256231212527115115543357578222223223111333222--211-1-2--122213333111111111112211211312223122122342222331141113133212121221112331221111311216553356312511112233313223375334421233334238BBA9A6313333333334433363335A3327721525751169227112547111322222232233322232222222222222222311132273224J77787974852D33332323142514121121123112124353221135522222221633223222234444444444A-444444446A229556557877CF623223456536444222222223332221311----------11--11111111-111111331344444878988477767775897858999464422244323227255472212212322222222111222243112121212111222321222221232112223221121221222222121231224264233253143333322444333223221-2222211-11196346755667576655-6545668546664555554CAC565579A85888AA696B669A523444432577777777777--223332332222232422213123221423122232222221365643555221221212333333333135453433425246563333323332322122111111--------11-----1-1-11---111-21-11---153323633324-2 1211122-412122211111132352321111131211112121111253122344411565321221-211212221321111111113331111311125323413324752268545344499393CP8-85C3333535633746354353736657C54141812724842251J4112362293225641133 * c.80.1.1 double-SIS domain
[ 400] 11----1111111111------1122221-22----------------------1111111111--11 3373M343333111BFELL-LDBBX9JIJJJFGDCD73651T7T---2---------2--VL72r1YzFo31111111----2---1-12121111----4433K-323---------------2-22212111133344---P12523449-------1--1--ADBW3------------22222111-3f11111---21------3--4F-113334---------K1----------------------------------------------11------13-----------------------------------2121-------1-1Q-55------1--21-2-11211--1--112-1--2-23332-----54212131262131111111-111-44747444332-2336112112324A4314232333333---------11--413--------------------------1---1111--11-1-2222GBABFB3324KHLK1R14121311124423211324242--31------------1114221754---22------445431J-64434ok-1-1-----------------------11-1---33--222333334233333333333---1---------7-H--1-1126166111-21-11-1121214111111--13294211---1--------------1111--323223211221---11211154451-B12----1----1--11-------1---39---14K211--1--3482---------1114-------3------------------1-444333------------------------------------11111-1----822 --8Bgq4-42211148CL9WGJMTgWT331333MO98BCB9BB334LHDPHGEFCATQF767--1121--1-1--12-111-----11-253C123--1-1153124194R5656313343133222548R6-756311-43263243314117574243523AA6A536AB7661222jG164F-113J-1127357E * c.1.19.1 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
[ 401] 22-31-2222332322-322222232122343333333343333322344333234412113112-44 2332322322322223322-22222522222222222265233223311222212222--222323422222222222-221422222332222---111414432532--------------122333322323333432224242232222222332223222434322322222322223333322222222222222222222222222222222222122222223312222222222222223322------11--1---------111212-------222------------------------223222122-24-22111111121232221---3122-2322243222321232222--2124322311112523334232222222222222222-22422623242134442244324332642435323323422222222222224221111111111-2111111112111111112226227B8565666655333355663333-365876882266535354634366443222254243333323253222322232222222-434344333333325233222223223-1211111112223222222554538443355434343343443433-1-4422-11--143433344444444444-4434443445444334436343333435454555565555445332244442-333333333333111411111111124343111213-1111222244455444445266664555444545544212122121332333333343333444444444433442221442222-------------------1-----------------12-12-2222231 11--244-512132566648976DBC64555446555767666565557887C755686455755454445564554146656645454485655E556646467A-5779AGAD7A45546579A4B4N*8287G7546865545675795494A66A68E3623AB33B26643225k22222758G6873364334 * c.83.1.1 Aconitase iron-sulfur domain
[ 402] -------1----------11111-22222332------1--1-1121211331----1---111--23 2242332333333342244-43224444545232223565333353323433665433223443469454411111113222343222324322221--242634343411111111111111133233533333433223332233433333333343333333333323324343333444333322233322222323223222333333322234323222222224322222222222222122223221232221212222222222222222222222222222222222222222222222222232222222222222222223322222222232323222222223222422222222222223433422222235662343345344444444443-54744546342366654585458753343326333323333333333333326332232222232111111111111111222233343234733777767666666677677766686456545447644344444444473222642222222333345452325242544432434643334333346234333335354724222222243346455437367243543333333333334233532-2342311111143444544444444454-444444444444444444444445684434444444444444344444444334344444544441143222222332133451113331333333334443444333436667476866554356633333333343334333333334433333333333333222233333311111111211----2-111-111---11111111121223222222423 11--232-411122344343434636244132222232222223334433533334443535222222222232222132222222322242423333352442221251C4556365545445533A4IZ4-57E75436446324443454B4945532635423433532544452F2233365683565352227 * c.65.1.1 Formyltransferase
[ 403] -------------------------------1----------------1---------1--------- 2341D4323341-1BCCII-ID99N6IHIIIAFDCD85561Q8L1111111121111311JF11h2Mh7f22111111-111111111111111111--11111611131111111111111111111111111111122111M2363355A11111111112117A9S31111111111111111121111711111111411111111115411211131-111111141111111111111111111111-111111-1-1111111111111112221111132111111111111111111111111111111111111132111111111181551111122--1111111211111111111211124111111111353111122411111111111111-33734333221124451131122225121313222222311111111122112121111111111111111111111111111111241112211233439A88854423AAAA393221211112332222133134423111111211111112221122321111331111112125227152212OD11-11111111111211111111111111111-141211342424323222222322111-11111111---81421312336266322-33232232333332222223245264323222222222222222222223211233333233232111122222213221811111111111111--12222212211332223362211222253621111111111114111111121122222221111111111111------------1-1-------------------------11111121111511 1145qy2-312-3438DR7UGIRageO554556HPACFAHBEE657ILIPLHHNACUOFBAA433444-34133333-234333344322B5D2241311396422-3B3Q55433-21--222212337L5-527121-222422222151-6263222232892D74AC85571222G223292133P321234437 * c.19.1.1 FabD-like
[ 404] --1----1------------1----111---11-1---11111--1--1-113--------------- 1-1-2--------111-11-1-1111111111---------312-1------11---1---21-21-221---------------1-111------1--11-2---1------------1-112------1--1-----1---1----321-----------1-22--1--1-----1-----2----------------1---------------1-------1111--------1------------------------------------------------1--------------------------1----------1---111-1-----1-23------1----1-1--11--21----------1--11---1--1-1--221--1------------------------------12-1----11------------------------1----12---11-------111-----------1--1--------111111-------21-31-1--121-1---111-1-----11---1------1---------1--1---2--1-1-1212--1--11--1----24-1------------1--------------1----1----------112-----1--1-2-------------------1----1--------1----------11-11----21--------------1---------------11111111111--1-21111111-------------1------------1----1-1--1----------11----------11---11--1-----------1111-111--13--1122-------------1-1---12-------1---------111---1--1-- H8355AN-*JFCIGS66886966655B778686A767869A449A8686597BC6788AE6D7224451344623451248334544567F96B87FAFBCA2756286G*BHMMIZIFIFGOKcmBSK**PDhNyGIEGMHHRDALBFDZGEiIVDFOT**SNLGINGN*ADYP2FMD*42233EA7779C3ANTOPK * e.35.1.1 Membrane penetration protein mu1
[ 405] ----1----------1-------291141512--4-------15C-2E-2JAD-1------------- 353-1----------------211-1------2111-12215243-------2231------2-3125851-------1-1-31--115534-522----3-2163244--------1-----111-1111-2627652221171547M6611211-----15411D8C-------------7-1---1-14534434644332265256655344536545321-----411111111111111111------2-11-22-21111111111--121--------11------------1-------1--------------556366564452442611-33123-1-11-117827351422--312---22-4421121125479343A57A822221222222-9A8A548A4621-8831133233333121221441327-111111112222177711--1--------------------1111-1143-143233222233454333334444231232321-157661521333462324131713----------4783873128C295ACC-D4643374515443A27--------------------21--1--532637513335324364234326423214----561------1-412213223343433-2343433333233123221432231112121122222222212521122221-323212322-1----3111111221-1118----------11--111211111112266865545489867456---------2112433333144234455456222------8-55141211--1---1------------1--------------26-321-11--B-2 -1--22--31----52424322322213334451-1-111111224433344643335233411-21----1--123-131----1-2136345224541442354-435DPOOXYMACEDBGAcSBeE**R3aKl9FCBDAFEG9GDAAHBAPCNGIG5BB8DAB5MDBQ79A5-46-------B414172144121- * d.110.3.9 BphP N-terminal domain-like
[ 406] 33322133323223242111222633311341222122211222322211372133343432333-23 -13---11222---1--11-11--2711111251113596-2-2-12-1---231-----1112-12221322222325123211-2145351432----11-131111---------------32432122312333341121143332232244111422113433221111121111-1-11--773546224244333333433A3A865333275544555555632111111111111111222--614-33-31-1224434321212222333222223333343334333122222222222233354-33313459G7778889C8C6AII69A7574145562244679233536456324-122---1----1-3111--2623311111111112--16--5-2431-45544238445442212-143233321212222223--1--121111111111--1----1--1---11-111-2322166154355643222233222333427225962-1232131114255461111-1132-----1-1--111-974D45747A887153452-6B4----34112112----1------------1-----87C321224143566546844454546594----11-------A598361777A7BBA97-77878A8778798777779BECAA446AA9899A99A989889766555571-544445444444--2------1121-3427334415--------233334343334233341522664323323---111-1-243364544566846-----------2-3--15222222-----1--3-1------------------2------4344483758-12- 1-22543-7337352455744335763224222656443443522246465AB84323322111--1211112--21111----1-43258454581212345353-3A2B55826A263554499392Ig91DBE4423626624541352374963623128618315A15411453A1225-43289441223333 * e.22.1.2 Iron-containing alcohol dehydrogenase
[ 407] ---------------1------------------------------------------1--------- -------------------------------------------------------------------1--------------------------------1--12-2-2--------------------------------------1--------------------------------------------1-------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------15221----1-------------------------------------1-------------3-1---------------------------------------------------------112-1----1----112222--1222221---1--------1-----------------------------1---1---------------------------5---1---------------------------1---31-1---1111-1--------1--1---------------1---------------------------------------13--1---------------------------------------------------3---------------------------14----1-11--111------1-1---------------------22222222---------------------------------------------------------------1 2---BAJ-B43144B79988678A6A86658578879AA98AA9888799B99977B789A98666662543556354455776556779B6966767655A98A9-Dr8*UTTYXfNMPFKTMwdIrR**bCsP*JNOLeLORXHPOMHSKGrLPOPNVbyMPPfDHCGKBGcW4BDL*HEEHFFGGMAKJ9CDDDDO * b.82.2.6 Hypoxia-inducible factor HIF ihhibitor (FIH1)
[ 408] -------------------------------2-1---------1------11---------------- --1------------1-----------------------------1------------------1---1-------------------------------1-----21-----------11112-------------------------11------------1--1-------------------------1444443261534353----32544---3-1--------3-----------------------------1--------111--11----------------------------1-------1----111-------------1-1-111-111------------1-------------1-------------------1-----1111111111-1-----1----1--1-----1-----------1----1-------------------------------------------------------------1----111---1--11--------1---------------------------------------------------------------------1----------------------------------------1---------------1----------------1---------------------------------------------------------------------------------------------1------------------------------11113-21111121-------------1-----------1-----------------1--------------------------------------------------------- 2-----7-----33733335454756544333334533333333323335456433334433333232-42232422-3223333322245435454444464676--2-*******dacWbnb*qY*f***-*m*NeVd*Yl*oMjaVMpQK*clcgf6AAF*I*25114--92-1--1---2--2213-----238- * b.22.1.1 TNF-like
[ 409] -----------------1--1--1-------1-------------------------------1---- 1-111------------11-1-----11111------11-----------1----------1-1--1---------------------22-----------1---1-----------------1-----------1---------------221------------111-------------------1----------1------1-----------------------------------------1--1---------------------------------1-------------1-11111-1----------------------1-11----------1----------11----1--1--------------------1-------------1--11111------------------------1-------------------------11---11------------------------1--------------------------------------1--1-----1--------1-1-1-------------------1---1----------------------1---1-------------------------------1-11--1-11--121-----2-1--11------1-------1----------------------------------------1-------------------------------------------1-------------1---------------------1-------1---1--------------------------------------------------1-----------------------------------------------------11-2 CC66694-E111**9KQOEA999HGE9667768AA97666676545NJIRNONPJIOLIJOJdJ9A5558D5GAAL95EBBFFDQF544u*RQGUR9A99EJCQZc-4I4EEI9A7LA8CHOFBLI8OBj*M2O9O5ACARCA*L99AE7N94cCEADJ64634683D125WO7C3393M6535Bf***I*l79DCHD7 * b.50.1.2 Pepsin-like
[ 410] --1---2243434522-------493351115---------------------------1-------2 1-23E224445212RYNHH-HL99OIHGHHHMPRVSIZgj2G4E3534412255555822CAE366ABA961111111--4-3-----1111--------1-1-21122--------------------------555542221------------------------1-------------333321--311444443342434443-----134434414--------1--1112-1--1111-11-11-1--1-------1------1-----1----1111---------------1--1---1--1------------12-3------------11-----2-2-1----11-214------1--1-1-1C67A1111164H9A641GCHDB44444443444-56B55D576AH-733343475967AA68474D5555568--------9---1566---------------1--------------35D422OHAJ5556973544533A8555524G4KCINJ-23337216479A79C21B--2-32---------14541E22------1-------121--1555574--21-----1-------------------2311115-2422122123A1111-184153----22--1----------11---1---11--111---1-1-----1--1111--12-121-11111-1-1--12-------1--11111-11111---2111111111-33-3----1----------4445433--23177773734343555234----------1111111111111111----------------556777----------1-----------1---------1---11211-1------1 ----444-422-53797C7I87CFGH9BBCABB8B89BAB89BAAA6779A8BE7B87788855555535557755523555555533399978A855545A8C9A-69293353262222332353528a3-32722223125-22242332215224457423243445-343-531-2211432A8A353489761 * d.38.1.4 MaoC-like
[ 411] -------11121111-1--1----1-----1----11--------1------1-21122211----2- --1-2--1111-------------1------11------1-11---------------------1-1-1--1--------1------------2112--11---511---------1111111-1--1-----1--11-----1-1-11--1----2-------1-321---1--------------------11111-----11-13-1---1--2---1-1----1----1-----------------------12--2----11-1----1-----------1-----------------------------1-1----21--------212-1--11----111---122-1-1-1--1----72-1---2-------------------------1------1--------11---------1-----------------------------------1-1---------2------1-11--1---1-------------------------------------------------11-------1---------1-1---1---131211--1---------------------111-1------1-1---------------1--12---1--3331------------11--11------------811--------------------------------1---111----------------1----------11----1-------1---------2-1-----1-----------2223221-----1121--111----1--2-----------211-----211----1111111111-1--1---11----------1------------------1-------------1-211---- 2456DBA-K8A576D63755647D997658677857573625344368755C67573466694459543464657652665443875564753C4E66475E4CBE49MNoaipvdjPKJLOQN*mJmJ**VBxU*JLQKfNNaMJPOLJjLInOfPQW8OOPOKJCRGCZCEIA6496eA5676INKi5YB987NGEF * a.207.1.1 Formin homology 2 domain (FH2 domain)
[ 412] 11----31-------3-1------1-111142--1112-----221111-311-1221112-111-11 65827214322222233----3--34-----4322246E8345363224554353255224432425694221112211-135322222121-11111127144953361111111111111122222211211222233---5342353322222233334423246613334222324422422212311422222222122222232775422233135343323333233333333333333324433311-33-22221122332-11-13332221111111111111111111111-11----1111111111111112------------1---111122-211-1131122121-2111-11-33385582222246B675476457522222222225-89489586375-77749889AA66455132632423233333333335354335311-------1111111111111111--1-13142223223DACAAD5444477AB4444149585485344436434453549255522313311111112234376231-12132622231211-2-2-35426225---1211111----11-11-232211133-24-334632333344445543334436--113-41-1---33441333333333333-333333333333333333323244223343333333333333313333333-1211111111111111111111222326477---212-11-1----555553435252444446B65666545441----1---31221213214433366565655553333112-221122111111113-211111-1-11-241-1-1-211---12----1---2633 5445557-LA71332564433344245453333333443434445423445545351453322321---1---211---1121223323464647241333225451537ABF8CC55552585DA4B4Ge7-98C3665F58F835564953B6A56A35664347968833954565n56474IDGH5C78395974 * d.227.1.1 Ohr/OsmC resistance proteins
[ 413] 11121232222222222222222222222323111111111112112223322111121112222-23 3242722333332224455-5411925555543555432224322332334333243222332263966921111111111132222222222322111232222233211111111111111222322222232433331114253332322222222223322232232222222222222222211145422222222222222322443422232442223333334622222222222222222222312133122-24423331212233332222111111111111111112222222222232133111222221112-11111111121332111113112113376343422242121122324322232222233443223343322222222222-33333233252232223433322224222433433332322222222222232342222222322111111111111111222222222222224222232222222222233312222222222222222223332322222222523222222232322322223232222222222222222222333232222222222222222222222223222222232232322222222222222223221-232321--11123322232222232222-222223223222222222222222232222222222222222222222222222222222222221222332322233222222222222222222322222222223422222222222222323322222222222224222223222222222222222222222122223311111111111-------------------------11211212222322 2322564-D5215685747A9C8CGE866675567486564764534753764554C765443564552533454343544333465445E5759C556369656522D4C9A687653545556B6M4U*B3DCL544555485464545426446643554849A567q23765674*44584BCHQ7MG5865457 * a.128.1.1 Isoprenyl diphosphate synthases
[ 414] 3314328B79888AAA52223118C89B9AEB121121111113314244335-9AB9AA98457167 -211G--12221--74434-35--6933333565656JJO25246312-331C8A237--AA73A3AEFD52222-11-2-11-1--2224213111--2435462617---------------11111111111-----11111---1----------------1----------------442--1--1134444464444344654733474451123123------76---------------1-1-1--11--11---1111--2-------------------------------------1--------------13148222212222221332222221---22434433331212111----3--B888111114297A2225447399A99AA9AAF-227229256L2-JCCCFFWIJKFD827429AJABAACHM2222222246641479------------------------------1DL65EDDBFQLNNQOGDCCBGHHFGFGGAFLLGABBC-198C78BCD98B5B23364---622222212---434-252324223522222-1-------1--2122--------------------1--2211556261A3A825455434633336465345--1----------34673343333333333-3333333333333333333657465544345444454354555933333332-644444444444---3-----1111-193E222242233342222BBA9A7713132AAAABG8E6DICA49AA---------2445654554A8B874434344333--------------------------------------------------------1---2-13 ------------------1------------------------------------------------------------------------------------------------------------------------------------------11----3---11-1--1---2----------511---21--- * a.4.5.32 Lrp/AsnC-like transcriptional regulator N-terminal domain
[ 415] ------------BC--------------1--------------------1------------1----1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------- 3312945-765376768855986675655357576985665655866666545599686656664565167457864-454456464556C68548645665499826B5*WbfaeeROSOKOU*lU*O**s8lb*YLRHRUOgVQPQKKbNR*UQdfaDGRPWVGCQLeUAIH53354*64444HBBD8A84234225 * g.41.10.1 Zn-finger domain of Sec23/24
[ 416] ------------------1--------1------4--------61--4-4IBF------1-------- --1-3-------1-21134-31223132223311213112-11221121212111121111131312444-1111111----------22---1------3-22F123---------3-----------------22212---21312911----1-----1-2-1344----------------1111--1-22221212311332112552-112---71321--1--72---------------1--1-21-11111-1-1111---------------1---------------------1-------11--------41-54222222222111--211--22--1-----1-2--1--111-1-131--2331-----332122--331-1------------23533522-22-2224115254412421-211222221-1111111131122254-------1----------------------122-21111-423213-111122311111125431112----22-2--31212-212--311-11--1-1----111-4---21173-11-11-111313--1-11-2112--------------1--3-1--1131-1-2---1-----1--22121-321-22---------------22-1---------------------------------135112--------------------11---------------------1-------11312---------------11121-111---1131-131-11--2--1-----1---1---1------1----321211--1-111--13114476--------1-----------------------------1--1-1---111 ----495-1-1332411-11-1--1--11------1-111-1-----1-111111121-2-1212---11-12211--11211241--1---1-111-14-1-2231C-3nlpehhpTNUTWgUzfS*S**h6*b*SWXUbQWXeOVXXTwVX*SxZaUFRDENHRHNIOMMaFF----8-1--123453211-1---- * a.24.9.1 alpha-catenin/vinculin
[ 417] 33-31-3343343334-333333332333333333433533433344433334434--3--333--22 3433364444422223322-22222322222233332344232222223232343222112222322262233332131---333333444334---33-3333343331222212-33-----34433333333533443334354744434344333333333457733333333333333333333-33333444443-44444335443344534443334443443314444444444444434433-1--33--11133--331---31333----1--53355555555555----------1--31133311113413311111111125244-1--5-4-133333447344113333441134533333-----445333333333333333333334-33333333443-3333335333433433333333334333333333333333433-----------------------------3333333333433353333333333433331343333333444453433333432343345333333333333333313453444333444344443334333334364343333333314544444443334333333364443445565545555554556544--1333433-33344444444442444443-4444444444444445445444544444544444444454544544444444-44444444444433-53321333334353545545414443414445434333444344454444534445334433333333344454444454534334333344433333342445533--------1-------------1-----11--------3--313333443 11---14-63-1333434323467A556522334633433333323343434334333343433333324433334333333344334546536674355344355-3944224342-2--43-4524-7F5-141-1-2431211----4111112251-2-3-1--111-2636442R3333458976B96795752 * c.1.2.4 Tryptophan biosynthesis enzymes
[ 418] 112-11111111111111121332233313211--322212131164854E81-2222342111---1 ----3A77BBED6A1-1----1---3----------4E46-41456547A72A624482256-8I954AV6--------1222-----32221222----11111122-----------111--13122111223144231138-6-2222-11--------42-1561-------------3442222-169FFHFHDEF8GEGGGEBBCBBBGGG577C866444444JI5AAAAAAABAAAAAA755775-1----2---43-1--2-----2224443333122444444444443333333333333322222222233B56AAAA9BA5C73522286745131621-2EC2--31222322215241-211233133221--236654744444444444C-32122333422-9BB9673697757312124K959832-22222222-332--53------------------------------11112333234555754555544335555456331112--1111221181412211111-1622222222--1111-6722212323111----1---34111141341253-33332-1-1111111211--22695261112211244121421141234422---1121------I6994B9799C7BBC75-8795B9C5A78DA777775BBCEE9977577777777777777C66A77783-BBCBBBBABBBB--3-----------1B8G555575--1222--52233211-465146244635745221466---------1988799999C8D6611---------------111------------5-2----------------------99B1221122222-121 --------2--1----1------------------1-------------1--------1----------------------111-1----3-1----------1-1--------1---11-1--21-1--1--11-1-1-1--111-1--21-1--1------1--1----------------1-1113---------- * f.22.1.1 ABC transporter involved in vitamin B12 uptake, BtuC
[ 419] 11---111111111111111111-51132121--------------11----1-1111-11---1-21 1581711244511132222-22113A222223644458E92422662112139231131156719276C8211111112-3242111122411511---1611352816--------------2121111111211113322122412222111221111211213321111111111111152211111111333332321423222323351353112311-1111115211111111111111-111115----------------1---1-111---211111111111111111222222222222211111111141222334334442321322111131311111217415--1121111112261153341111111H7A212624333344344444C-544437478D2-D778ABDGDDBE844437A744455775555555535553323-----------------------------134I338IG8ABAAC9C74444A9EB655644I6EBHGA1177A3561282F3FB363211266222222212234311126-13123441121111111233135411123112222111111111111111122651312625652333332E333324542471-2211211111134423645554544455-4555654545555555555898232353223232334233332644455543-45554555544411-21111111112135732322122222222244564572742498786CCB4A7955898111111111145582222273B55436555544433331111111111--------1----------1--------2--------111111111-541 ----321-21-24242667D665AD962223224664444444334566A9HVH776543231442471334342442235222313332C468347CA5132315-3F55133222111111111131241-11211211211111-112111-21133113533434AG13311524D3343131135332584544 * d.79.1.1 YjgF/L-PSP
[ 420] ------------------------11131111111-------12211211212--------111--11 2221211111111111111-11111111111111112142143611111111211121111111114212111111111121111111221111111111111111112111111111111111111111111212222211121333333333332223223332545322222222222211111111111222221221211111211111122111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221321111111211118822221121112211112223111122111141131113111111111211111111111111111111111122111111211111211111111111111111111111111111111121122222222222222122222222222222113121222222222222222222322222222342222222233232243232232322222222322221112231211111111112111111112119989B512111111111111111111111111122232111312222222232222222222223111212222222224222213333323232-33443223223233333332222322232323233333232222332223311222222222222111211111111121212222222222222222222321322222222233432222223331111111111332322222222222112121111111122211111112222222221111111-111111111111111111111111111111111 3333A561KA8344555336566656555455666655555455555555555747566556776666569976CDB69B8666667765A6575E8665544ABG37DMBFKHDEC999B697JF7O9o*D1FDN7696J7AC99A678A76N8A8AC7DJ6DAA9P6-759665797*56587OORY5KE58BCFG7 * b.130.1.1 Heat shock protein 70kD (HSP70), peptide-binding domain
[ 421] --112-1-11111111-1--2-1-12221121-1----11-1-11-11111111-------111---- 4682--1311112243333-324442333334133343221121-111-1--12112111-1--1-32221-------111-1-1-223211-2331--1112422212211111123222223222433-11332223211-1112124421-113312131212335113112--2111151311--1111111111122111123--1111111124521111111133----------------------1-221--1-11--2212-----111-11122122222222222223333333333333---111---13-131212222232242112111322---21231131131121222-1-173D755343455346453333333233333333333-2232233244-15223645566-124253213221121222222222322122-311-12111--11-----111-111-1111121531----255554522333441455555445122331121-1-12221211-142-3323233222223353422411111226411212442432244424A6221323211112341232322221121222333132244113333222333233232332-1343511-22256566555555555555-55555655555555555555556633257555555555555555555435563655555555555226322211---13463222234335542433234443532131333233141-111121-----------1111222222332222311-11---1212113122332233333132322-------------------------1121-12--12931 21-11-G-855-55721521211222322222212-24342431211-21112812111111343221132122211221---2333541-11--112-2-1-56522S-KEFHGfG5D99CD7VR2NBk*K3JBL9B7CJA8DBAC6A7E9CRD99BC55CB9584I7B79O852474P-22539DDA386AKCKJJH * b.36.1.4 HtrA-like serine proteases
[ 422] 33213-33333333341343233122222223223332333342232123322-32323442332-11 2443523333323344455-5433865455566777457855553663433289834533779354779643222222342132333344443333111211533223134444443434444212113312124788532234322122123221222221123432231312232312114434411224255555455455555534223255345531213333332412222223222222222231111----31-234--1--4-1213322321112133433443435451111111111111222111333334234222222212123221---2241122433-12-1643333263412423444421122658563345567644443443346-43755733243232222243225456443433443423555555555456233462212222211--1111-1111111111113336313434357756553333446733332454745842333255244456673335342224222222222363432446543123443354444462634733255322322212122123232223223255228332334323333354644433345365212353322233333322343334344433-3333344333343333333687332224333333333333333322233332222222222222222224443333333233222222222222222344444233335222223436232322534222222222333333333333444332222222222222232221122--------122---11-1-1212211111211111132254252122221 21--323-733112233433462544522111121142222221114444348445233232213121131233222-32133332311321333354422-15332263516221-212131113-417K21436111121123131221112212121241312-311C12311133U2223286DB3AA2451222 * c.48.1.1 Transketolase C-terminal domain-like
[ 423] -------------------------4--1---311--1-----2-----1--1--------1------ -14-1-------2-11111-1---2-1111121111--11---21-11-2--22111111----3--212--111---1111-11211421--2--1--3C12-733--1111111111----221111--111132212---2-112222-1-22-----1-3-1-12----2-----2--1-1--21--------------------12212------4-122111117-12222222222222112212121-11--111111111---121---1111111111111111111112122122221122122111222221118121322164131111111111-2121-111-111-1--21111-63123----611A-34233-11-------1-1----1---2--5-3-4-1-55D-4-2----33---2333-32111--------3333111---1--111---2111111111111-1-12-1--2-27329WEGNKHaEEEEGCAKSRQQ7SQIDD8F6--82P51P--B231I1-121324G7--24--1112269211-1--41-31853314-44172-1--7x3311----2----12222222211-11--8681A5211-513233232111213-12142-1292321-1113H3E4761A881A9BD9-961C36856B9B8221529885EBffD3C45673667575754932233494-3GGGLGGAELJL--2-1111112112-589111162111112251668655811185MOFKPCOA8CB88-GCC111111111266928B88B755332145444RUX222211-1221111----1--111111121-1-1111-11111--1---1--1--12111-4-3 31231-2-2111111-1264436445121322313133233442-13216412A322353231-1-1--4112114111112134121341512621-1234--14-4-1427334-1514214661527J3-734-23-21365222422112331262343617141313396-11151222236A62321212153 * b.106.1.1 Baseplate protein-like
[ 424] ----1-------------------1--1-21---1------------1--11---1--1--------- 3452334333333543447-45336344444335558477377C7644333433333333533486A9C6633335335433333333555333333333333533643444444434433333333433222334555435554366333323443434334333674233333333333335333332C3366666696369969933333476633493433333334333333333333333333333433333333333333333343334333334333333333333334333333333333333334333333323333333335835333553333343333333333333433333333363533333434333344444353544433333333333-33733345333363364445565453433337333334333333333333343333333433333233333443333433333323644334453443434733335534363434343354433333334334537543334334333454343333354363333343343344333344433558655334534433333333333333343333333333333333333333333434333333343-3333333433333333333333333333-33333333333333333333334535343343534433545433333443333433333333333333333333444433333334334344453333333333333444344335463443354433333333333333444444334333343433555533333334433223333333333-33333-333332344433333233433434333333333 --------12------1-1-11-1111-------1---1----111----11-322111------1--------1-1--1-1-----1111-13-----1-11--1--51514--12212-2----14245----21-133-1-1-1424-1322--11212-21122-161261-1-1--1---52-51-6--31122 * d.131.1.1 DNA polymerase III, beta subunit
[ 425] ------1123334232-2-------11-----------------------241--1-----111--2- 74H-1--------112222-23--252222214222158411-63611-2211-2111--211-1-5251----------1-1-----AAiX-61-1--36136M3S-G----------------------1---1--21-1-518122211-----1-312---52363----1-------211--1----1-----111-11-11121---111-----111-----111-11111111111111-1111-------1-------------------------------------------1--------------------1-1---11-1-121----222-----511-------------------2-95447----131D88---1211122222221223-4443434A572-577354477667211211122122213222222222114-11--------1----1-----111-11-----2-3443-2--514434234553223754431253C235---66442522634199114----1------------2-131---1--13----1-1---1--311257-------------------------------1416928218233355354432532333------1-------111-22------------------------------344-2---11111111111111113---------111111111111---311111-----23331111-1------11122322-211-1411111256232321435----------11--222222231144A9C996883222--1111------------2------------------------------1-------B-1 2345865-J564866BDB3B666GDG36689875647553355746987BCDCB23A684475517753546245442555A96455236C9D97A69A75365A9-8GAWGAFC9DJGG5B9BEJEQFR*A-GBSBHGJFJCB7CDG7F9JFECGBDB89EBIB99ZDLM88BC5CFAm6757ANGEM4TD7AIBEK7 * b.68.6.1 SGL-like
[ 426] ---------------------------1---------------------------------------- --------------------------------1-----------------------------------1---------------------------5------------------------------------------------1--------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------1-----------------------------------------------1----------------------------------------1--------------------------------2-1---1-------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------1--------------------------------11------------------------------------------------------ 8656PID-M77599BAFC88A9CBCAA9ABA9C99CAD9BBA9CCC86A867976AB98D8C8763641452817572256565556A9499F889773C3E8GDC2F*FcRZJEMPIHGCMMIjVHfL**Z3XTsEIFDXCNRODJNIEKCHkJLRIJGOIKKJA7IFLJCBGF8QGC*A75HHt*v*9*mBG8HGKL * g.44.1.2 U-box
[ 427] 1111112222222222111111221--1121122211111112421222243211111111---3-11 2223323455532433444-433343444444333333333334633332223334431133424444543333322223422334333333233311112111224232222222222222222222222223212211333233434222222222222222322332222222222222211222232223333342332233322222223232223123222222222111111111111111111111--11-1-1-111111-11111111-------21111112111111-------------222112222122223333333333344433322334--3232244222321222222111242333411111324453235262211111111111-4535535628212334553464664222222244342222222222223323142221222221111111111111111122222232222222224323223333222344444422233432222222333322322332222324222222222233411212232322222222332234523221223232222222222222222222222222223223233322222222233322223222111322321122222222223332333333-3333333333333223333222224232222222222222222222222322222222222222222231111111112242222222222222222222232222232222222223222222222211112111123323333333233222222212222222222332222--------113-----------1------1------22222424342332 1111----51-1--1---1--------11-1------1-1-11-1------11----11111------------------1----1---11--1131-11--1-----2-dPJHOTDAG7EFGEeHIUAm*Y2kTOAKBEIEDLJ5FJF9K89HILBBU49B9CK5CGDBPBTR41-11A1112153491333212213 * d.81.1.3 Dihydrodipicolinate reductase-like
[ 428] 22213111111111111211111143342344223222222222323212332222233431111-22 3343344444434242444-64334444444444444444355543524444445443334444444555322222223222421122222222221--222222222222222222222222222222422244333332224155443452244333333445344453332333332332323334423233332333333333422222233334312224444444322222222222222222222222233222222222222222211113333333222222222222223333333333333233222333233133333333323344554222334223223422456332233343222332233322222234332223333444444443443-333333432422333333333333222223334333322333333332442232311----------111111111111111-122432223332222222222222222222222234223222222422222323322232343222222222233223233233333333332546444564333344333222122222222222222222234333254343232344544343354333333331-23223-1-11133332423444334333-43343434434344434442433323243444444444444443332332332344444444434222222222222233322333223223212332333333323324222233332433433333333333334344455555545453333333333333322322222221111111-113----1-1-1-111---1111-----33333232222212 2223333-83123323333344543443333334533333333322122222221232222233333333443334535433332344424333332322233334235398676654455443883838c5-74B3644744744544544364755637G27334333743434233f3324464773644535333 * d.129.2.1 Phosphoglucomutase, C-terminal domain
[ 429] ----1113224522321231111-611344332321------1-515352444-1322--13511-11 2291511111211121111-111111111111211112251324212311223412-211222222214242---21---214-1251C98B-833---254324C958-------111----21-352-3148375579-11E2DB6B57A--1134424336238AG8-1---1-212--11-125311-1------12-111-11415521212-13-213111221331221112122322221----1221111-12122--41211112111111122232231111111111122221221222133211222233--31333-22-111-1--211222123-42243421831-422-141212333--4-1111424623322422434333331335-723535432321B5575422447754242211333423-3343444432254223-------------1--1-1--1--11-2-143421----65554567222233763333227794133-23343464244123-1132513323112222325732-255236222622247664437345453975223----1-----1--1-1--22124321114451-31-21322112--111113221---4523------3223-322333222223-33222224223232222221423-222232323223344245411221-123-----------1----122122111122211111312111112--22224221-2-33313123444-1-222564111111111252322222-1-2223333323331111--5-225511----------2-------------------------51414533433324 --11775-622355885777BCBCBCB8878799898C8A89977687A86878768788885676565687565994897678668778A658788766566DCF13C484443333332232542627T4-647232-523643342243-63334624547462744C88315394t47746BGKO9K825DCAB7 * c.87.1.6 Trehalose-6-phosphate synthase, OtsA
[ 430] 111--1323454443411-----54334-514141---3122-22142312121---221121131-- 366-6--21122-221-22-2---3222222241111146-323111---2-635--3--11116432711----11-32531-1--11111-122---1525477614--------------23434443232112212555329644332-1446354343212244244132234421323-12-14533444443342425433362224345353324522222264322222222222222333231---22-----21--332--2--23333422224224334453444322222223222223223332223146576667666866655557874545414531554533234-22512133-86552---1-535744324622455555254554-44634343126-8445678A8865324266B655566689899999925576452---1111111-1-21----1----11-2232473-8BA69534575222224498233414989BBB322666754337784915443-5-5-22---1-233646214-6348314332331341213522122-35734--222222-1-1-----7536622323224633342333322343335433363--22222------42431424333453734-3444333444344444444353234642234323222222242533222231-354445544444-1-3-----434414137331323232123322545353543254665646656454536753-3--222-3342544444233227665556777------21543122--------1-1------------------1-1----113--112-1-213 ------5-1-1-111513456A377892212236--3565534-111151679A3542-24221-12-23222212-22114443-11-36418521---13112--1B693658741123341541226E4-333-21422325142112233251145882C1416--9-138373-96473365484664374328 * c.3.1.8 HI0933 N-terminal domain-like
[ 431] ----------------1---1------2---------------------------------------- -22------------------1--------------------12---1-------------------1--------------------11----------1----------------------------------1---1-----1-----1--------1-----1113-------------------------------------------------------------------------------------------------------------------------------------------------------------111211--1-------------------1-----------1-------------------------------------------------------------------------1------------------------------------------------------1----------1---1-21----1--11------------1-----2-----------------------1--------------------------------1-------------1--------1---------1------------1------------------1-------------------------------------------------11------------------------------------------------------------------------------1----3---------1--------11111111---1-----------1-----------------------------------------------------------1------1------ -688EIG-SC94FHGABBB9857B89ABAD8BA7579AAA6BAA999BBB88B9A8BF9CCD9978BC6896874AB857D888868DA8IBBAFYA885BG9PQN6FHLjNRPQQL9FE9DIJUVDVF**V3ZKbIBIMKJGOHIKEGEOEGVEPOMPacTIWMNHNFHT6CUH48HE*IBFC9TKYcCRMEICHELG * b.69.4.2 Cell cycle arrest protein BUB3
[ 432] 11-1--179A787A47-3221331521222127C1--1--2--11222313531122132-72611-- 537231133411-212311-13--33222222521234343574338543323421-211452-4369984322243132628124335EEC-C11---1855626C-4--------------2212226163728AA77-1141357A35A1-22723233249757A52-2123142121-5233711313C9C8B6595869835311116896-415115111312692121111111111113212441-1222331123--24151443243422-------2224112213-1111111111111-442-44441331413332433133-244-4224-2--23811562B412432--131154285222-----81124-1-222-111231233334-6456485B432-4555326364554132223324221322222222251211542------------2211-22221221----1113--333345441446222255385556144366222136641521-313111-133-2422211112144334224632288-7364537666A5A242445259522311745346-3-------121-22111121411612-3-2-1-3---111-1312--31613------4512253133212211--331231211131211121142312241423234354323545241----111-123232323322--313323322323273253212-31322211-111111233-2421112321-11443235222221222-63121----11213112212212211111-374466551-1-11114------1-1-1-2-1---3311-----1-111--1213B68 --32214-1---1232321111---31221-1111-11122-111121335333661211221-------1------2--1--------2423221111111-544--R2b9CAA988698899JA7C9LsD2BAK6889A67A77A986878F8459A36B4443543481144436473325195372465411-1J * c.68.1.15 Exostosin
[ 433] 11-1213388B97AG424-----2B44A3384---11----1------1-322111211113533--- 35P1821222211113311-1211291111113222458B1-115E412222689213111-4173G4A24----3---11-81-1--3333-21----1322223C14--------------122121131111222641--3913315333222112322111143431211111111114442224-132333332442343334225524334224551321111267211111111111111111113-1121123------42---111111-------1------------1-----------------------12215-------1-13111---1-1-11-12--43-21-222-1222-1-4156333-2---11A664232322233333333346-11832B33GF1-CBB1A57DECBB4433-2535176558---------22---11-11----------------------------2642-654ADBBBCC6333388D8654724B7C6A85-15562143394H3FC121----2--------1--412452-11-1--1----2112---2-11-1361-1------------1-11-113-1-11-1251143171111111-1411211133122--21-1-1--11165CA2837A98788A77-8777A9C78689777777A8A8ED122B8AAA9CBBA8BBB997533666521465665555557--111111111111-1822225122111122212222122-2-314434226623443163541U1M2oo1-123223333322222256466344-------1--------------1-1---------1---------------2231113131-113 ----173-4112---44537766977A1122224431232122233747868AB4753723222111---112231---21---1-11134343427556531154-276B6223644352264AB3516Q3-4363334633512342422163444712547455237B11411-1211331-574948A1132317 * c.1.11.2 D-glucarate dehydratase-like
[ 434] ------------------1--------------------------------1-----1---------- ------------------------------------------------------------1---1---------------------1-------------2--12---------------------------------11--------------11---------------------1-----------------------------------------------------1---------------------------------------------------------------------------------------------------1-----------------------------------11----------------1-----------11111111111-----------1-1---11-1-1----1----------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------1----------------------------------1---------------1----------------------------------------------------------------------------------1--------------------------------1-------1---------1---------------------------------------------------------------------------------1----------------- -1-11-1-1-------------1---1-111----------1------121121112--------1----1------------------1---1-1-----1-------1*fudqhVTLOQXaY**T*T**y1*i*QTPIvTchdJVRPNmUG*WqcVdFOINWeB9JCDKACZ*----------111--22---1-22 * a.77.1.2 DEATH domain, DD
[ 435] --------2-----1---11-------11------------------1--1----1-11-2---2--- 112-21--------1------21113------6111-211-213-2--133--11--2--5--1-16133------1----1------23-2-1-1----22--5-4---------------------A---1----------4-1211114-------1----1-1111---3----------3--1----22222224232333531J2221226---1---1-----1--11111111111111----1-1---------1-------1--------1-1---11------------------------111---111-33-33111111----42-------------1-1-1--1-----1-12--1--1122-------1113---------------------21----1--1-3--3----1-11-1111-------12---------1----31--------------------------1-1----------------1--------2------1--1-11113221111----------2----11---------------11-1---2211---1-21-2-1--1-21-------12------2--------1-----1--------1-------3112----1-----1-1---------2-1-----1------------------------------2256-----------------1----------11-11111111------------1-1----------1--1----11111---1-----1-2----1111-11--------------------1-2--111-1--111------2-22--11--------1---------1------------1----6-2-----1-1--- 1-11122-3352-12-12384514635332111-211443334122353255C65283351311-----12-22111-12-11-132-14331142-11A133D4e--J9*ZWwNbH8F3BCGDXU8ZBt*Y1WMYBA8BV8BRB3858AL55MAABCF377IiAQhlPdq**FY-25-1-2249L***5**-348222 * c.87.1.10 UDPGT-like
[ 436] -----132222222231211111----------------------111-2121-13-111-222--11 4841532222221131111-12222211111222223233-22211142221343233113352333C8611111111-------1--11-1-1--1--2C76793A57------------------1-1---5232235---3-232122311222222222224242212-1111211-1-11--112---------1--------1-111-------1---------41---------------------211111112111111111111111111111111111111111111111111111111111--111---1-12-2222222212--111--211-1-----12-----2---2111-1--5-177731111111--1--------11111111111-11111111111-111111111111112331111111211--------13331-3-------------1-1---1-----------14423433343333333333333323333333422323223333233333334322422112222222222213313-1-1--2-1-----232-121116636F5-3--------------------1----221114124565158788653566646477461-121211--11133121213332322233-3333322333323233333232112113332223233333323233333332-211111111111-1341111122221121111111111111111133333322222222322232322222221111111-113-1111111111111338777756622221-3-332222-------------------------------------21--------1-6 2111674-844-664744344445454654444333244444444443464564444545555655544655657552555444443335A3436333335335663656TIGFKKLCCDBCBBFEEICc*H1KESBBABFCDIDBDADCHBBKBECDCBOZMSCSLdNYsGKHP2444Q5326475A957C348CAA3 * d.92.1.13 Leukotriene A4 hydrolase catalytic domain
[ 437] 11-1-13555555553-212111231122153-1111111111----1111121111-1112211-11 5353541222221286433-3311573333336585A8MO241937221322AB9343--54913494A511111111----6-11--22211111---1333442423---------------11-112111115454411136-211221----------11111121-------1----3332411-51122222242442322243331124215714111111115421111111111111122221-------2---222211---11------------------------------------------------12--1----------1211---------2---1331-1-113212212--2-2E554-1--146IEF2148566555555554554-33C44C47D66-B66A77A98A55A98445993233388--------442-3522-----------------------------31CY4-FC95AFGIGEA68884DDJDA99929KEX9OFD25BB8BBA74DAG4JD452----211111111---3892211-1-1-22111111111111-222237-12--1111111--11111111--11111112311224312333333243432321324---121-------32221212331211135-3515212522315552555556225516463656666656536743144451-144466646666---3-----11111134A---1-------1--44444422123937777664C2678723441111111111122222222223252244444333-------1----11--------------------------------------1--------312 ---1333-421-4226764C885ICE93333553457444444333646AADKJ7786444621312111222131111122223212132373333222215332-2C67463232221124154242CQ6-535232143442112-13-25555265533756543472353323271111244674332365345 * d.177.1.1 FAH
[ 438] 11111112211112211-211111111111111111111111111111111212121111111111-- -12-21-----1-11------3--12------322221542-111211-11-52221---211-2122212-----------1--1-1--1----------1----1-----------1---------1------1--22---312122--322--2---1211-23434--------1---21--------1-------------1-----1-----1-1---------12----------------1------------------------------------------------------------------11----------111--1---1-------1--1-----2-11-1--------1-----------111-11--11-----11-23222221222-11-11-2-131-222---21-112-2-2-1111-11311--------1-----11------------11---1-11-11-11-----1--2---112212111111113111111111221211121133-12122132--2------1111111--1311---1-------------11----1-----11-1112-22222----------1-111------2--1---1123311-122212--2-1---1--11-----11-11--1---1---11--111---1-1---1-1111111---1-----------------1-------------------------------221--221---------------222221-11-2322222221322223222-----------11-1111111111---------------11-----111111111111-1------------------1-1-----------1-1--- 3322121-512143245857886A88766555522377777875765435ADFE98933443434222-31244321-12233333123362564534223532342472GLN*OK*75**5S8**f*8**D-JP*AAFqp56F71D*J*H74*5T4Zi32414B34231535514632T1113687AH4D321776B2 * b.30.2.1 Amine oxidase catalytic domain
[ 439] -------1-------1-------1---1-4--------------2-----21---1------------ -41--------------------------------------31113---------------------213----------2-------2231----1------1-1525--------------------------1--13---4-1---11------------1-2211-------------1-----------------------------------1-1----------1---------------------------------------------------11----11-------1----------------------------1111111-1--1---11-----------11-----------------41--------1------------11111111-1--21212------------------------------------------------------------11---------------------1-------------2222----443231---1-------1--1------1-------------------1-1--1-------1------2-------11-1AA--------------------------------2-1--111-----12-----1-22--2--------------------1221111111-1-1111221-11111111------14-1---11111-1111-1-1--1111--111111111111---------------1------1--1111---1------------------3-11--------------------------11232-------11-------2-331121-----------------------------------------------221 6813FCQ-XBF8ABI65FB579793B5AA9A788468676756787EC78MGCHEEMA5DAA545322133423432133356532131E985G4K66546G7TcM19Wk*NCGNGFJHBDFFGIFKfGl*G4ULNBGEGLIFDGAGLIDBG9MHGFDFRRTLlC98B7BB44MAHYRDsB9ADF*Vd*A**E9GEBBB * b.69.1.1 Galactose oxidase, central domain
[ 440] ------------------------11111---111---11111-1111-1-11-------------11 1212211111121111111-11111111111111111111-11222111111212112111211111---422221111111111111111111112--11-12211212111111211222222111121122111111111111111111111111111111121111111111111111111111212211111111111111111122221111111221322222112111111121111111111132122221121111122112112111---11111--111111111111111111111111111---111111133222222212111231111111111111133111211111111211212211111111111111111111111111111111-111111111111111111111111121112111111-111111111111111111111---------1122111111111212211111111111211-1211111111111111112111111111111111111111111111111111111111111111211111111111111111111211111111111111111111111111111111111111111111111111111111111111112--11111------11111111221111111-2111111111211111111111111111111111111111111111111111-111111111111--11111111111111111111111111-211111111111111111111111111111111111111111111111111111111222222212222221-1222222211111111121212-1-212121112212111111112111212231211 12--674-3343A8B345565555455554545564566666644467554535445556673422321322323221223333334348A8487H7646363DDB-C7IaRGJUUZFCC9EKEdRDRDo*N1SHcDGHEMHGM9BGDFAJBDXFLJHH7CE88774854B44E7334AI39563W***4*X2-877A3 * d.15.2.2 PB1 domain
[ 441] --121-1233333341----1--21123225221111-----13-233334333---11-1----1-- -11-31-111111-22-11-111122111112144412211222211------1-12----11-3-1122-1111211--1121-1--11-2-3------3---2-12----------------21222121212-1111-----41643333233222111423656A41111112111-11-1----1--------------------11------111--1-----112--------------------1----------1--------------------1-1111121112221-------------1----------12123433323-4-2111111111------213122-1--11------12-23112-----212323233343211-11111-11-122122222-2-21112-26121113--111111-12122222222221111211-------------------------1-132222-2-211-1221122111133331111111122221-121-12211224113-4411--1--------111112-21-1--11--1---211-22126111224122--11111-12-2-1-----32234------31--1-2211112-1121-3111-11---21-----------------------1-----------1--------------58------1--1--------------------------------1---------123-2-11--------1-1-1211111211232232--111----2-1-------------11----------11--1----1------2---1111--------1--2332--1--1-------1------1--1-------1--- A54365B2I372446C6A3445674799684564346555644637A86C7BAA889984454232131442424331425334315325776756768355537A56RCKKNMTOLKGGEGGJZVEhJ**X2XSZEIGCOGHKCEIJACIHDIHMGGH7FGAEDGAKDEK76BB1DC6*968G7NMXW6OMEAECEH8 * b.2.5.3 Rel/Dorsal transcription factors, DNA-binding domain
[ 442] --313334222222332-1-11--133111111213432333411211111212555464411212-- 1131523222222222211-13111311111133335689132454424552546333224254645546322223221112122212333313221--5334233213111111111111112121121111114222411111225311212221111212211223322231122122112111311132333333433333334232233334333333334434533233333323333333333333333333233333223332333333A3333333344333333333333333333333333322223222311222222222311172112111343231232111111211211121144311233421112322224322242311111111112-44333345332133332222224412311221111132111111111222111331111111111-11111111112112111111111133324333335433333333333333333343433333334444444323323543232343434232343342322312221232232323332122243242232233333351253433432133227655224365555555644455555345542-3222312222243455453443333344-333434343433333333355534553344322422233333343242233324333333333332235111113333354344454553343354453222223434435456455555555655533343333345553666666765644323223332323123344332211-11111213----3-22312122221311221-134433424431312 3432752-823235445541424343-453645324521232243433655475125166743222321343341221122121213432255324726313448513I777433331115444631427F4-4432222432332323142-73A43332138252122647C42553F5783383265767A44344 * c.66.1.30 N5-glutamine methyltransferase, HemK
[ 443] 11111111111111111122111132233443---1------------1111111111211---3-11 244-522222211221122-2211222222212222243322221111111122212111221332244431222133--1121-111334313222--3543475334--------------1111111111212222211131634222111---111-121-23431-1-1-11111-1-111111-1211111111111111112233231113221212111111-1111111111111111112111111121121211111511111121222211-111111111111111121111111112121111111111-111-1-11112122111211131411223-1111111141-111-1--31711111111111213--11111111111111111-1111-111222-122223344222122113322333322--------------11--------------------------------111----------111111111-1111-1-1-12-2--22311---1------1-11--1-11-1111--12-13441-222121222-3231332344444552211111111111-----------1-1--112344224333435322233333323323--12111------11111111112122221-1212122211121221222111113321111111111111111122111121-111111111111---4-----111122411---111-1111-11133333332231311111111111111222----------22242222222222433434433433331---544455--------11-----1--------------------22122222223613 D94686D1M11487B799868677776556667678596886765457889888777688787783443544547343444666767765D798887688457CB819GDKGGDHGGCDA9CE9IFAPCg*H-JDN9D99EDEIE5DCBCEB8FBFECBAE9AAD96E98A78C65GGB*987BEMHLP8TFFC789AD * f.51.1.1 Rhomboid-like
[ 444] --------111111----------52453321-11--------1112-111-1---------11--31 --12522311213222211-122221111112111112532445222224432242312222322213221111111322223212-1111-D---2--1----1--4---------------1----1--1---4223311111-112---63-1523224131211121211---1-13-33122--13--11111111-111111-1--1-1132211211311111--2-1111----------1111--2------1-11-----2-511-B----------------------------------------------2121---2-----------113--1-11--12--2--1--1------113--12261-11112--11-2-21221111111111-113-1413122111---1-221211131111232322-2-11111111112--123-------------1----1------1--1-11211222214222231111122351111-12541322-16511312225552122311-2-1--2---111212411-121-22311121-1-4----44423233222--1--1---11--12--1--1--11--1-4----211111111-313211--211---1212------------8-11--------2--42-----2--------42---1-1----2----212------32------1---2----2----22121-1-1--12332-----------14--2-454C--2-1--------1-1111-111-1111-11112112111111111131213112222222-11---------------12-1-11-----1-2-------1--11--1---1-1-111-- 613144I-jMM576C57A654885755AB489644369885A92345965955896B768373527342213333211--4332144225BI7AA6855762CDC829*2LJTFIJGCBG9DEBRGCNDk*K-QKS6D8AOCCOE89CBBGBDMDBCHH367C9877OA9865F3BTLQ*KJLEIOTMh8TDG8AAJFg * a.4.5.10 Replication initiation protein
[ 445] -------------------------------------------------------1----1------- ---11113111111111----21111-----111112121-22112122-----1-111133-112111111-1121112121-11--1111-1--1--1--1211111---------------11111111111111--11----11---11-211-1112-2-1111111-111-11--1------1-1-11111121111111111111-1111---1-11-111----1--1111-1111-11---2-1----1-----11--1---1--1-2----1---1--1----1--111112212-12--1-----------11--1111211-11112--1---1-1-1-1--1--11-1-1-1---1-----1----------------------------------1----3------------------------1-------------------------------------------------------------------------------------------------------1---1--1-----------------1--------2--------1-1112--1---21-1------------------------------1---------------1----------------------------------------------------------------------------------------------------------------------------------1---1-1--------------1111-11-2--1-----------------------------------------------------------------------------------------11121--------- 1233GIO-933-99D33546897787877689A87878777686558944548535686A9943535312225535535542322365579A3BAH5868465CA81C*6TSYOSfNOMIGJQNziGkH**Z4tZ*GJFDZHPZJ8MIDFSDImGOJMKCE6*HEA6W9LH68T97EIN*ABAICBADF5DCWTBFCAN * a.140.2.1 SAP domain
[ 446] ----2--------------------------------------------------------------- -----1---------------------------------------------------------------------------------------------------------------------------------------1------------11------1------1--------------------------------------1--------------------------1-11-11---11-11---------------------------------------------------------------------------------------------------------------------------------1------------------------------1----------1---------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------12----------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3*--11C-XEC7ABD22-22111121111122111111112211112112212111211212-1-11--1-----11-12111221---13221211111112112-15AlAHGHFaSMQNTVYfdT*Q**TAhVySSQRgNUWHPUUPLnGK*PaJOMMx*GFG9CEAB*32IG1DFE*212328--22-915GIIHH * a.126.1.1 Serum albumin-like
[ 447] ------------------------B1152-64-----------1-------------2---------- --41E21467A21197633-3A--4P333333D9AAJMyi234C59512112MJP534--44D2CEYEKF21111344----82-322-----1--------------1--------------------------34321----4--11-----------------11-1------------6732411-512333333443433333644422342145631-------82--------------------1-1-11----------1-----------------------------------------------------14-254335445343-2333--------1--2-A7223113352312---1--622------63JAA--9785628888888677A-126--914H72-AAAC668988CAGA41-57J4355586222222228441-123-----------------------------1-8B--7gZJPKMMQMJBDCC8NNTUEEGE5EVHeTihT11DE8DCB87OBI8TQ233141121----------776-13-1211-2-----3632647451-1113-----1-11--1---------------32112-124-4-1-1----1-1-1------11----3-1------54543439667977767-67968686766877878879A9341227376757677757566A43444443-312232222333----------------691112-2--1-112217785739464C1BA8A4CAC48CC93776111111111----52222224234-133333222------------------------------------------------------112111---- ----------------1------1-------------111111-----1---1--2-1----------11------1--11-----------1--1-----1------1-4-----1--1----2--------1-------1-------1--1-----5----11----1---------------1--1-1-------- * d.110.2.2 IclR ligand-binding domain-like
[ 448] ------2355555542--11-1-23111--24-----------2112211211-1112111111---- 13-17313224424BHB44-4B11DC444449CABAHGGE1F7A-1241211444344--44614575544-111-----453111233334-4221--1332222221--------------11212321111112211111411-------------------111--1---1--11---64634--141222222222222222223222222223321112222225232222222222222232223111----1-----11---1-1121111112323122222122222222222222121122-11111111111112----------32111-----1--4--2133424521332121--1312C79E-------GCB2-1E7DE833333333332-2252292512H-311112521123342D56785365568--------411--44------------------------------1C874-3A96A755566566655586777747849BCC92255543578C5B786234----63-------11-2274A5532121312231235441235323486131111-11111111111111112214--5544C2347435899868687797777777---142-------44442425444544455-4565454545444445345565444334444444444444444544444441-333333333333---6111111111-7821111112111111111998794644222FFGG7B88B77779544111111111-433533333444335434343333-------2555555-------------------------------------1---------2-2 --11562-31-133177654746655756344445314442446553A454465236445452251111121-132332313433422222276461223215788-4A5823114-2122333542335A3-225132-423511323152332334333-13112212-53211-12512213169A87221-1-23 * d.38.1.5 PaaI/YdiI-like
[ 449] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 51BK--4-3--------------------------------------------------------------------------------------------------9--***p**ncXTVaob*rNpR**xM*l*SZabuRlnfMgRVQyWR*c*kqh**iLbKD8KA7TLOFG---1-1-21---------1IHQ*- * g.5.1.1 Midkine, a heparin-binding growth factor, N-terminal domain
[ 450] 222-12132222221212-----21---1--1-----------1-12131533-11121111222--1 43A2511111111171233-33224C43343443432564352593222111112-12--33423437662-3332212-1-22244445342422---14-227544411111111111111145353433376322542113342234422244312221343324322222223222224344332121311111-1---2--11221121111-4211--22222243111222222211122-11-21------1-------11---11------------1111111111111----------------111---112124111111121212221111312-1-242233431-33-231134--226444322122239AA3238424222222222222-4533635432338888445B8643823543324444233333333331332223211-2122211--1111111111111----152834342133335636335344763333334562333244342442237546524322223311111112222222B4723212322222545334564222238451232322223223222222243335232243644344211111112111111331351-14444------22643322332333233-322232223333222222222333433343433333325354332232223415333433444441143111113333344951111111111111112222222242335555695743555285722221121211111111112213332222222222222112444334411-1-1214311111---------------------24433323333642 ----321-----23377A89886DCB76625344543533244575E98FAFJG5878587713323332325354443322212233333673335244535422-596754338A424534534387QtA1A7A4422455463555564573434634135346334734632242m2223445AA8A87252454 * d.160.1.2 Carbamilase
[ 451] 11-2--2322322322-2222322311222432222222222222222334432231-1--3112-33 2322422222223223322-23332522222222222255232322311223213222--223333434222222222-221422222222212---111314432332--------------1222333222233334322252222222222222222222222224222222222222233333221333222222222222222333233222233231233333234133323333333333332331-1--1-1---11-----1-111213-------23322222222121----1--------222222222226-34111111121233221---2-21-2322223222221223332--2122322311111423334222232222222222222-22522522222123332232223232642434222223322222222222223221111211111--11111111111111111222722798565445455333344663333-354776882266523344744355333222254233333322243323422222222222-434344333333323234222222223-1211111112222222333553535563333334344443333433-1-4422-2111264443456666666666-6646565666666556658454443435454545555545445454355553-444444444444111411111111124334222314-1111233344444444465244444555444544444312122121233334444445344444444444433442221332222---------------------1---------------12--2-2222221 11--223-411-1247643557578775445754444444344454434658985466464544444434455454414554444444447464465554474687-41458935293452324453547e4-3383333424433334334484643425C23233B35855322223k2212263AA4852234433 * c.8.2.1 LeuD-like
[ 452] 111122-------1--12122121221-322321144--3112331444423822--12221133-21 12--11172212-7-4344-45222135334121215141-7542434231-325313--34625255334-211-1111463-11-23456-354----344433231--------------1134375--3216668B1--9-366556A111121222243216893-11-11-11--115511----43232333522334233324422223653222343422333244445444444444323332223442334223443435232135324322454334444444444433334333443332555544445252334342455341245542321122532542233123343121131216263232-31-9321223336336322222221223-3353596-52115113111612121612223214342348888888832231251-------------112113---11------4331131-153331255111122224233133942232126733A3A1-655-722C3423333212121552937326C1116155351163371284386465922-113123332133786464554-1155-35271-2-1--43-53215-23121-522--183341-----12268132332232353-3112435122332222223421434423322213233223221322221222-111131111222--3-------1-131332522212232336141---1122142-3476512123111-6333321212212112231115141316-1447643325435--331122331-------412-1131-3--13111212121411112-212-2----231 -111325-8444136-24134515354-122--24--433532656312324432154812422-122-141-112--2--3421-4--1542662221-125534-3K493333596883644AA2E6LsD1FAJ5524D1796656826415375551123-34422423682145-62651353234858542217 * c.66.1.45 N-6 DNA Methylase-like
[ 453] ------------------------1----1---------------3---------------------- -13131-111111233366-63117166666333331243-3-31-12--1-112121--1151111-1-111111111122-121115445-4225--3513421223--------------222244312223222231115-1-83--111---------1-13131-------------1-2211122333434444344454422113344522222--------321--------------2--1--1-1--11111--11---11---1-1111----------------------------------111----21111222222232323332221311-14211111-112212122211224-17442-----558674345633433333332331-55955953241-51121242323148331223----211--------3211-23111-1-11111--11221252222221-13-1-32-222126666555566677876766367877676124558443354662343A1--272111111122324443211322-1211---1-11211-455564-4---11-----------11--112132165-531225312655544375454333554--13334------21211212444244422-422233223344222222222211111232222222222222222222222--222222222222---2-11-29A9B154122222221---11--1444444621221343353343333331111--------23226211313342211111111111111--12994455--------111-------------------------1221121222-1-3 4366EC7-932-33379E6778898A67676554545A88766555566997CF7A5E67893732222443534333333355454563229496121225156416P9v8DADDB86554A4975C4Lt6-75A5374635836455355587A46757DDAC657473CFAE5777S99787FMBvCID8B7B977 * c.19.1.3 Patatin
[ 454] ---------------1---------------1---3-11----1-1-1--1--1-1-1-------1-- --1-1----------5321-1---31211111-111-1---211-------------2------6-2222-------------1--------------------11----------111-------1--------11111--------1--3-------------2111--1-----1----1------1---------1-----------------111-------------11111111111111-111----------------------------------------------------------------------------------------------1-2------1-----------------------------1----------1--------------------------------------1---2---------11111111-11----------111---------------------1------1-1------1---------1111-1---------------------------------------------11-11----1-----1-11-12-111-12-----------------------------------1----------------------------1------------------1-------------------------------21----------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------1- 4143KG4-9522DDHFBCCGFECE9DEBA9999CEE9FCE9EDBABCEDEGGFF9BBHHECDEBEA996CABCCDBB8BCBEFFDDEBCCFDBEAIAAB87CCFHD9CE8WPSRQQHHIBBDIIcQLWG**u1XMWGHGEWCIUJEIGBCLGCRDQNIIGEAHJLI9RLOH9HIFACABqA87BBSQJoGcD78DABA6 * a.22.1.3 TBP-associated factors, TAFs
[ 455] ---11-1--111--1-1-----11--1-1-1---1-1------1--1715B34-1------1-1---- 3-416121--1---31444-4222834444452111--24-54F111------1------772-K18E6D1---------2---2---5343-1--1---1--2711-1111--11----------1182137-611--2---719853647----1----1-172272G-------2-------1------C1313327222D5-36-----3-2-23144--------B11--------------2-2--1--1---------BC-11-11-----311---11---1-11111-11--------1-----1--1------9113111-111-2-72442---3--21O2DI-743-2B1P-1251---1112-----------7232-111---------------12--2-111---11112231--4411---1411--2--3-------------32----1-1111--O-------------3195--3311--1-A-2132634454---56777-D-121--2--22-2--2--151-11-5112-1---122113-16-4-14224--13-1---1332-3Q1---2-KR4--2----------11--11-----1211---821--1111417--21-111124813------11-------1C3----1121-1-1---1--1-2--1-11------311--221-----1------------211--21-1222-22-2-----Q-11111225411B---------2-1---11---1--1-1-55-2111A--161-15-24----------1-1612112F22-2-13---21------117---1-11---1--------11-----------------1----154--121-1-3-- -411g25-C7435423765C4434447563636164378756763655168575287A9574335213-11173345335-4243-1431E27364C13336137k1148LA8BEGJB683C67QU6IAO*E3E7N6745HAAVG786B8*66N8HGGK4DC3877MB4CG3AJ53-64A23266GK69A8B46BFCG5 * e.8.1.4 RNA-dependent RNA-polymerase
[ 456] 1111113233233222-23332122111-11-1-1--2333322--21-2112123-32222231-11 446271111113-142322-221115222221223244B7344721232221613212114443458554211111112-243221213323132212245533644371------2-111112221412233512112222213-2221141112---1-221-112323-1-21-12-12222332314-422222222123222255444422334434533444335343333332333333333334111-22-1--12222111111111111111121--------------11111111111111--111---135645222222232435222222212--52-3221254215334333322322422323322226553235454633333233333-334225345511544244765455272235564477554222222224432144211211111221111112111111112222236F43644258556677555655686666476485954223354332233465511421112211111111223541463212212311216575666535445232611111--111-11111111112222113322223321445333121222243222231-1431221-11142333321222122211-2111121111221111113212214423333333333333333211211112233233333333312232222233332132322233221111222133333221115255553434444443333222222222-22231111133233554444444422221142223333--------1--111-1-1-1111-111111111---33211232323424 34--332-823-232233343333445333333343422323333333343354333333333222211122121221222---1111246432362234322445-45388976684435574FB474K*8287E45327469225644862C355675AJ46643K84M34655453m3333595B73343266554 * c.48.1.2 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
[ 457] 222222222222222322222222--------222-----------1-22123222222222222222 2223334333333333333-33333333333333333334333233332333333333333333333333323332223212223232221222112222112111121111111111122222111111111212222222212323411233333333323232333423122223221232211331122222222222222222222222222222223222222223111111111111111111112----------------1-----11111111111111111111111-1111111111111111111111126211111111121223221222112222113233222323332232122232222211111222222222222222222222222-22222232222222223222322222222222222222222222222233222221111111111222222322223221122112222222222222222222222222222222322333323223322221122312232232232222222222223311122121122221232323232333322312111111111111111121121121223232323333333333333333433333341-2333222222233334333333233333-3323433333333333333333223333333113111333333333333333233333333333312232222233332332233323333433333322222222223233332222222223222233333333133332223233333323434333332231121111111111111111111112---------------------12111111211222 4366657-947487844514445776544343366744544343334444547634444545663543444344533343444345755473475556644865632635E99795886756669B7C6IyC1ADE7867C68A859866A66B667778A57E6767687A7C64589*78856778F3CB87A7761 * d.101.1.1 Ribonuclease PH domain 2-like
[ 458] ------------------------1--2-1-1------3222-2-1-4-5112-1-1-31-------2 --11---------1-1211-1---221111111-----11----21------------------1--22--------------11-11----------------1--1-----------------------3--124423--15-612B44------------14-1284-------------------1-366666664757466653577665752436455111111DJ-------------------------------------------------1----------------------11-----------------AB9E999999846854883---573--11161A9352553231352211-41122------1-AAA1-2899B8----------3-75A6766A-4--634888768966G61--323444338211111111-2211K6B--------1----------------------111-133--FDDECFF6688BBED889969CID3986-18A864A24C1178-35B35349A-------2112AK3IA4A26EBMMHFD189BD4738521135427767714544351211111114A22411BA2476711737FEDE65ADCDCBA9BCJI---1226------573111----1-111----1---111---1------321234---11111111111111111-1----1--423233323333---2-----11111-C4D---------------1111---11-548886BIFEC99AB79AC---------76IIFEDDECFDHKK2222324333------DM663356---11-1161--------------------------1314333223---- --------2-1-1-2----111--1-----------------------1---2----1----1----------------------------1---1--------1---1288E9IA64422574BC675Rh73C9L455584664454339438496652358P54343481-B5----------42-4--2131--13 * d.110.6.2 YkuI C-terminal domain-like
[ 459] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------1-------------------y**m**pSLMENbP**K*Z***-*s*KOLInPYfQFaJCLz9F*Kibi*6B4--586863D2232---------------1-------- * g.27.1.1 Fibronectin type I module
[ 460] ------321---21-1---1--------11-----21------23---1-2-1----1-2----1--1 3FH-L------------11-1-113--11--------1--3----2---11-21-1--1---1-1----------------1-1121-2-2--2-----2MD33DU5-C1222222111121213-7-1----2-111-2---2-21--441-----1-11-13121211-1---1-1---121------41122222433-262216----1-32-1--2---11--1121---2221221---211112-1-1-11----222---1----1-1--112-----1----1-1----1-------------1---------7--13-------1-12133----1111111---211--1----11-3--22-43--------2-13241-21142------11------412131-12-122-23-3351--1-1---1-------22222222-111431----1-111---121--12-2----------111-11112-4111212----1113223-1-242-1---2314212--21--55151-2322---11---------J11-2-1--111---293533C12--3-3--1112-21-121-1-1111-141----5212111-1--1-1--221--1----2-21-----1----------21-------1----------1--1--1--1---1-2----3---45-2313-24-1-11-----1-----------1-1113---1-----1-----2--2-1------1------11113--11142212-21--13-2-122---------11-1--------2-----3-331124445--61222234----11--2-1--2----1-1-11---1-2-1----2--11--12--116 MB58AC6-H56266E221432-3225121255472132332232223646C83934543675162341-3256241153275354915A783265854123C2347288LyPNMJGJHJAEBHIXdGY9**M2bNnEEDEWGJQGAGJECPDDmPCFHPIVVOLi89FEFNFPaI1542Q55311C8Bf7AB679L76F * b.80.1.7 Virulence factor P.69 pertactin
[ 461] -------------------------------------------------------------------- -----1------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1-------------------------------------------------------11-----------------------------------------2-3---1---1-1---------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------1-------------1---------------------4-------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11------------------------------------------------------------1------------------- 1222--G-1--------------------1-11----------------1-1----------1--------------------------------1------1------C*mnchyfRQQQQWQeaMgP**e2lXwNPSQVNSVQGOPUFSMN*RhRV********3NnZ347*---------------------1--- * d.171.1.1 Fibrinogen C-terminal domain-like
[ 462] 33111221-------1-2212313122211127312232311113123-411-123224331--1--4 436111111111-111112-24112222222142223123356431324322212112116631252345321112122467232632767A19221--24242346332222222222222244434334345322232112213325553123357632323142352231134452263112111123241111142221213443211541111522-2122222352133434333333333223121---1--1---1211-----------222----1--22222223222-------------11211-111-11427555355393A14334333234211762353333333231111261243955822222415644444423544454555555-55633333365144472486554633547424444443433333333445348831111111111--11111111111111111334653444448554574555555556667388543235324323235335643443232334533324436554452753355A777A9B2543554565242217433334264557545323332334523335335235474543333934543443754441-144421--11122224322223245422-2322523243245422442222322323233433444234332322222222233333333333312522222222224242322323234445455332322324334243232452342444232333332333445542222234333324343323322223247558887-----1--43-----------311-----11-----13233121116541 24111-4-411-1--1-211121-133114222--31---------1-21-22214121-1---1----1-1-3-1--21-------1-----311113--2211222E1F634264241344434174GW5-64C33525324343241334524235382241321115--833113T35133B325-364435425 * c.68.1.13 Cytidylytransferase
[ 463] 11--1---------------2---1--1-11------------1-112--41----1---------11 DIz23-21222-2--------3----------1234--2231-117212--246A-----3223215B742----2---------1--7666-222---5333FA6A2D-------11------------1--1-3443922165942132311111121111414432111111112111111------511444444331226532--2222332111-2-1-------D-1--------1113-1---1--------------------------121-222---33354234343-----------------------1-131----------212--2413-3--21--21-1-11-1-22113---F-D1111---1----211111---------------------2--1-2-111121212111111-3-1---11--111111111-111-11-------------1---113-1-11--------1---22-1F7767B312224426333322762454112234282--21621---13-22---------332974-2----2-1323321-3-2134--22125I-1-----------------1------1-----4443112-1--1-113---11243122---22-2--------22------1-111--------1-----1----------22--31111-11222312111-------------------------2------121235-1---1111----1--3231-32----1433433224252222242-111111111---111111--11-1-222221111111--11441122--------21------------3---------2---1----2-2--1746 331154A193C19748598BBD5C6AA6643478655525444446658AGEHEAB9CA9DB3434585324552CB-MCA44333677B8858D95244474348-7E4iEBKKMKFBEAGGAPVANE**H2LGbEIHBOEGIHBFC88SC9MGECCG29C77751794425BB1A35I53596847A7C7312556F * b.68.1.1 Sialidases (neuraminidases)
[ 464] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------1--------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 11--------------------------------------------11------11----------------------------------------111----1------i**t**iOTTTWha*xH*M***-*r*NPOVxVYnZHXNQKfMNsWkZZa9MLIPJL8dGHn**F3---------------------1-1 * g.39.1.2 Nuclear receptor
[ 465] --1----232523322-11422-51--12-42------11----1-------1----1---1-2---- --2351-2---2-19fQ66-6I--HW66666BIHNI6JWo-b3d1--2----442226--12B135E7735-111----1617-----1--1-11-----2---3--121----------------1--------66687---33------------------1---1-------1--1--11-122---12----------------11-------22433--1-----4--------------------1-2------221--21115----------3-------------------------1-----111---111--22--222222212-13-------1---1----87-1--1-2------1-2--733A-----3-MCE1-9B7AC833442443442-34A33E39856-411112321432964728592224268222222225111-823--1---------------------------67F9-6uaHfGDDFJH5577799GH887868W8UTemd36785748BCO9JAPT567---121-------2-2922-121-----3-----12--3----122121-8---------------------11----2--1114-3--1----2-1----1-11-111--111-------1-2-41-3443333333-2333333333233223221111---121211111111111111122333321---------------1-111111111-2313111------------443242422222556547663424552a3---------1---21111111212114----DGI------2-111111--------1----------------------------2---------1-- ----111---2211375856555A9B8332322632566666655443787DGD66B444334-112-------1------221-1-1-55458553113233545-283926235233433535B263Bd4-7444343723442324232571633B36922362945H1224-13-----1123194421713241 * c.123.1.1 CoA-transferase family III (CaiB/BaiF)
[ 466] --1-11-----------------12332-21132--1111111-1-1---21--1311323---1--- 1----111111122------------------1------1------111------11------1-1-------------435-1-1--1131-4--1-------1113-1111111111111111--1-11-------------------------111111---------11111111111---------124454555444545543544124441--33121223211122221222222222113321---------------111----------------1-111111--11-------------------------431-22212224152---411-25-21152-----3--321-11--12--1----1-------1-1----------------------1--1---11---------------121------------------------1-----1-------------------------1-1--1111--------------------------111--------11---2---------333322222-1----122211-2--211111-21--121--1------5524333334332222222-1-11--33123144231-1111--2---12122124----111--------------------------------------------------1-----------------------------------------112111-1-1112333332122222232221111111111-------11-311--2111-212-2212234434444433433-----------------5112211--------11-------1------------------11-11-------1- 31-1-11-5--1--132311---233333223311--------543-1--5848344211323131-1112-11----1--1-121-1-14-2-223111--3----275*ov**hdKJILNOJbWFaN**Q2XLjFIJGdKKVI9JJFESEBYIPPLRm**OtiVQlJSkNJVP---181---1-11-31-4222111 * f.54.1.1 SNF-like
[ 467] 112-212112221111122222--22221221---11212311-2111-2----2--22223122--- 2412-422333432-------2---2------22221284-22221-2222222244222222-222242--1-----2-2-2--2-23222-2--4--22-121122-222222212222222----1----2-22222---2258453353411-1-1-1163623312---22222--4222222222224444453424345432----1444244222122222222-22222222222222-----2222222223222222221222222222211111221111111111111111121111111121111112-124422222224242-22244442-22222422224222222----22222-2222-22-2623442344434422222222222-44626A4422223228222222224221-2223233222--------2--22232------------------------------12222222224222222111122223333132224465124442113222224222623222-22222222442232121122222222221-222242222122323-2222222222-----------2224466525122-2424222222222223222222-2312422122244444444444444444-44444444444444444444444454644444444444444444444444441444444444444222222222222222221222221222222222----------7233334444444665222322222222234446666645466112121122221211242443333222222222-2222-2-2232222222222222111-3221212222222 54--622-F41356622222333223222311213222222222222222222222312432212222224222243-442222222222422222422232276823C548D689644454337K2F2Q*A-95G231374545153234126342343436343692696C526BLB*44296YGTW2JDEAC9END * c.1.12.1 Pyruvate kinase
[ 468] -------------------------------------------11-8--1313-------------1- 1-2-1--1---------22-23--1122222-3333-111----12------121-------1-1-1-24--------------------81--------1-3721478--------------1----------------111--22432214422----1-22146652------------333----------------------------------------------1-----------------------------------------------------------------1-------------------------1------1------------------------11---------------2-1-111-----12322---11111----------1-11-11-1--21-111121111111---4142-111132-111111111111--1-------------------------------42-2-1------------------1------1---2----11--11111111---1----------------------1------1-------1---121---------------------------------------2-4---1-------------------------------------1----------1--1----1----1-------------------1------1-1---1--------1----------------------------1----------------------222---------1----------------------2-----1-1--1111111111--------11-------1--1---------------------------------------1113 11----T-1---5678BD74453383355654555553232332335578DDCDGG697875543334335334333333332332444FCABIAA98AB78AOFV-9A-zUURZcqMKG8NMMcVOiMk*O8kOoJNKEaJOMMEOLEGQHIdLPVOG42C37T*7*DHH65J-1UMCB8B8WBJUq*7ZHC5223-4 * b.118.1.1 FAS1 domain
[ 469] 11-21-21222112-11-221--367821782----11--11-521311-442--1-1321---11-3 2A7-512455622122222-2311332222231222213315282132311-447111--5351624544212221111-42612311325114441--15442434-1----------------11-1----2-855441-13-D57734645332233225536A8942332222422125734411--44676668762577776243323778155212546686493211121111111111411-1324312422-244222241222222633332342224111112112235333343533331331113334283267777868666275428764431321343FL452142424332-4-12-733E-----17LGL8R3CDBDF5555555553A-JNIIDOGIA94-978BBA79L99B44122B256956645222222225111-C45--------------11--11----------33A2-35423CCC7AA4646688958877378AD9CC8129A4A3488CCBBD3335212532111111123797A56212336447442-423412334111122323212-212111-1-------43312453732422142237576336555849547541--4723------33323222222222232-2222323323225122223547552424554344454435244222223322-233333333333--15---------1354222232222223322332222131--4245464436353545423-11-1111113444666665633433121222211111--4-222232---3----1-2-----------------1-------22141-21---2-3 --1122-----------------1--1--1---------1----1121--11111--------1-----------------------------------------5----1-------1-----------1------------1--------------1----3-11---7--1-1-----------12---2-1---- * a.4.5.4 CAP C-terminal domain-like
[ 470] 11--11----------2132321131121--2--11111111111---12222-22222221-211-- 2442522222322233333-333333333333333344542556442222222222242233424335533222222212233323332222132231-22323223342333333323333324433333333422255112235774777555555555566446776555555555555122222233234444434334644534466433343433211333353543222322123332232112211111311211212211132221212121112111111112111111133331122122111111111111333342233233443344222333521421533325333622424113333322241232322355334323332233333333413253353355425444644445653233212544432222222222243342462222222222233323333332333221562323221211222232332222334622223332433322223222322553343222322233333333324444334242233334253132322443353346333222222222222222222222222233333244433243343444433343444353213323311211134433443775354634-84463455567663443453333333333434535434363345353333532333333333333223444444444433732434333333214333333333332252665945335765534233333333334333633333544333422222222322222924455442222222233--------------------------11111111112322 22--11222---1121121111112111111111121111111-1111111111111111111----------1---------------23111111111121111-1E121112211-1--111-111161-11111--11111-1--11-1-1--111111211-111512427A86*789BAKEMP1AE6831117 * c.14.1.1 Clp protease, ClpP subunit
[ 471] 11----1----------1---1-------1-----1----11-2-1--111-1-46746563----13 2253332333333343322-24224422222444443787234332222222544345--3-82339423242222222342323222332222333--24225453-6-------11-----2333223232333553411153356344733333332333452634642432552434462233232224999998A7678876833334687623253323222224A22222222222222223334456444454446644564452445562233222222222222222222222222222222233222333235524333333322233334222362223222234234425634482323131877B32332229593333344433323333338144245534332466644373473522321455232253C222222222242245----11--------1----1------2-3124465445522C7765C7433355EI44442487E7B95325495473273968652432335222222223232343563232363-22225353333245655662725723333334252222222253323322312244-2232222424222432474242-3-1-122122242866252222222222-2222442222222222222333673346466666666666666622242423222422222222212234434443343322422222223332222255555452622332233766435532532333333233-465533333334341-11111-------12222244322222222253-1-1---1-1---1---1-11-----255331511113-2 -1--32--7631111112-1121312422----3---111111---11341535------1--1--3--122122-1-331---1-21213111212221132312--52112121--------11-1-261-321-22--121--11-1---1---1515616211-23-1-1211-1a223216446-2---22121 * c.78.2.1 Aspartate/glutamate racemase
[ 472] --2111-1--------21-11--2-----1--54534332326653731173411411113---1-11 ---11111111---311----2--1------111111384-1121-1-1---122-1-----2---12-11--11---3242---11-44431422---21--1-11-----------------22323121232111121112-4662444333323432235247774333333333434-----112-3522222223122223221444522211111-312222222-1111111111111112312221-45-1211123333-21112221222111111111-11111111212222222422211122311111559G55575766633376266646432-44312231-331111112282-121111-----121--11112121------------1131111111---11------11-32----2-1211---111111111-----11------------------------------1---2121122222211122222122222-23221224--11--111121112-121-4-----12111111-243273332223332331122123345----1-221124311111111111111112---116575334356678777589877786987972-211--21122254553455555566656-565566656556666566557577445566555565546565545555555613444444444442221---------2113344445522222333311111111--5722123222233433222---------16557555555666744444443332222--1311------------411------------------1------1212112111121- 2323336-I86232668567786AB97443444655755545553575887BBB5585556644533324335343313336663534499485333333274AA915I8C4763954334653B93A4Iu7-A6C45428564735561843E475565FG44353541456562875*8877794576589899876 * c.23.5.1 Flavodoxin-related
[ 473] -------------------------------------------------------------------- ------------------------------------------------------------------1-----------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1--------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5133FCG-WF7599C9LJ9476586766656678655777687243D8CB8BAA7AA7866A611111-12113111-11111111121TUBL**y1227J42BBB-DdF*OTQSRNIBGBEHEtUBlF**W4hQrAEDBNGFNE9IECELCAUFTHIJBGF9MJwBSPPOCGH82*FZR444wMDC8HECEA9FKNN* * g.85.1.1 MYND zinc finger
[ 474] 223233433444444221434331733636B6111332333331223127767112122322221215 5451222111111122322-23--44222224433322221323231111-11121-1--2211212342111111111111321211445424112--383A765365--------------163123434157111--111318KF6A95222224256368357766141111141111112111132132222222212222222211332221112111111111121111111111111113222111111111111111111111--11111111111111111111111111111111111111111111111112111111111121212112333131111111111112131111111111217222512222322211111222222-2222--13-22222222343-6553665897884154565233339473333333334442112--------11111122111111111----152323344357887875433366974444447597879-145423566532352246341254222222211263256645233266111112242538412124813322322222223233333335453522661C5A85CB7766665A866658488567--1631511111165344656666666666-6676666666666566666777442268777878888878778665565652154444444444411252322322222755633321211111211133333333563388888797699967889634324413379845555596676654444444322221--111222211111111211-------------------------11111111111221 1122113-3-1-112422322222222222222222222212322222232222223223221-----------------------22232323331111133444416---------------------1------------------------------------------112866M333A7F57G1C97443232 * b.38.1.3 Mechanosensitive channel protein MscS (YggB), middle domain
[ 475] -------------------------------------------------------------------- ------------------------------------------------------------1------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1--------------------------------------------------4---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----AD----------------------1----------------------------------1-----------1------------------1----1---------1*ihh*nZONJMLTOrjMvN**m4uRsJMNNfNOSMIOLNKWKHsLdMPROMEN*HC8852L34*3--------------------1-1- * b.18.1.2 Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)
[ 476] 34837323444433444434533995679598427242434544356445979277677562215-44 2311221111111142234-52116233333321113167231222212111111211--2221223323321113332142312111224412------221111122111111111111111334442334-2222342225131121111111-----111--112-------------3341233232133333333333333323321133412262533333324333333333334434322224211121111211111111121111114443422211444333344332222222322222111342111222633333222242423221333413242432244452233352122311225311222212324344233322222222222223-2121132234126443443355653211221342443431111111112212634-------1---------------------1133212222533333222222223524222344534652244443464633442429212111-------14121432432432264433-533243543223237541------------1-2----1211222231222222232222332222222223223--21343------22322223222322323-2333322323223333332232342122222232222232222222322221-211111111111--132112211114233111111-1211211111111111111254445232263223322211111111133223333332244423221222221111--5333222211111111111----2--11-12111112111-22144553363351321 1123311-EB3687754314651-3-122153443341-12-132156224133333--2-1321-2313-12--11--21--11-12273349642436-724332296I8C398C5566987JE6J4MvD3E7V3623F2AF83A874I64I565DA33699257B6649G61-243J3131-45321A2343245- * a.7.12.1 PhoU-like
[ 477] -----14232222222-57873334--34646-122211----341321443531---11------42 3341532333332366744-4511744444436555447545542231411134533311446143555451111111121133151211223111----3132554-311111111111111358546366514-----111424334445344433333353335453353533353533443331114234444444444454442243434444323-11-111--332111111111111111112--1--------------------------------------------------------------------2314A333333373814444675334111221577C641-34A1113113144444411111545762225335644444444444244344343463-555444544476564434543434544555555551333373311------11----11--1------111113544333334856887588886688888876889466414446544444444545549464342454345113454-558756896788714351655623353343441-1-11111121111111154156116254444143433333443333434444443---7441--33355441554444444444-442544444444434444457557334555555555555555554444444314444544145552321------1--4644633331311111111144444443444488886897679776766111111111154454444466555221242211111116531442233-11-----11------------1------1------1111111111333- 2121-11-21321-1212322222322--1-421--11211111-121321234414121221-1-1--111----1-----------11311243-12-1-12---1732-11-----1---12-13-4A1111311-11-22-1112-----21122---1211-121---212555V43453B5692644741115 * d.134.1.1 Nitrite and sulphite reductase 4Fe-4S domain-like
[ 478] --1--1----------1------1----------------------------1--------------- ----------------1-------------------------1------------------1----1---------------------111-----------------------------------------------1----1-3-2------------------2222--1--------------------------1-1-----1-1---1----11-----------1----------------------------------------------111---1---------------------------------------1-------------2-----------1-11-2-1111--1--------1-----------111-21----------------------------1---22---------------------1-----------------------------2-------------------2---------------------1-1-----------1---11--------1-1--11------------------1------------1--------------12-1-------------------------------------1-------1----------------1---------1---------------------------111-11--------1-----------1-1------------1--------------------------1-------1-------------------1-1-1----1--2-1--------------1--1---------1----111---------1---11-----------------------3-------------------------4-- -2--I41-81-31-BF1-2K-1113122251-1-114---1---13PN1---22223TE155C221---W11-1--P-121-3B123-E*1C13KG311K28139*-12118IB3214--2122222B28R4174A131-111W111--1C-1429c3B5L18uGZ*3-1-D-W2-1c-91-15-LGGj26331****4 * e.8.1.2 Reverse transcriptase
[ 479] ------4-22222224--3131-1-1152-23---11------1--1-13AGD111112-121---*1 GHZ1821222222111111-1A--27111112488853A4223325422222354122--82527-AC891---------1---32119792-4241--19384C6F44--------------21-1111--12233312---6261223212111111---111954221--11----11-132-1-1--1433333332324254431112342615333--111111-41111111111111111112112221111223111111111221-------1--1--11111111111-------------111---111112234111112232211221121411--221-1431-1--11-112----B2F2331----1368961-22111122122222113-9686878D52--311211331-43-511492A4544668222222224443331------------------------------1168521311467766942222665E4566236768B8811556A61445661B7--362252--------233444362---11-11----23-2115--3334BN-41---------1---------11-125522134362322-11--111111114211551--7--212111132131411112132221-12121222-11212212232344711111122221211222215331---31-2222222122221112---------44624---1-1-111-1---333433-11-5434436646569948657---------1221112112331242327374333---1----551111-1------2-1--1--------1-------------14----111-4721 -1-1--5-5--1--1746442-1634811122313-21321122241264B8AA683555631124221122-211--1-43221214423143363551371615-2LKT3A994B5425797D9475Ks9498H52A58636457844C32B7EEAA8CB58763A5343656159272522-465452556B9AA3 * b.69.2.2 Quinohemoprotein amine dehydrogenase B chain
[ 480] 22234-226555646614-----263333242333232333332123122232133433331211--- 35B3311111112-24422-23114822222485551654251756312222536221--444122634612111322523362222244441322---1634591639-------------------11111-1422111112122323312222------11132232------------23411231112666664685566455554424754253644324443444244444444444444322234212-12222223112212344222222221114113333333333322222232222224223332222464365555666354244422225554164222332213293344443216323454221-1-16682-1--11-44444445446-235225546631A44C563A76562-3741373243454222222223223322411-1111111---------------111-2-3F42111-34776733222244542222229364557-1343-22111-4432121212211-------1-12-1-23-212221122212121212-11-2-7316-2211-----13-2111111----144432431312532232232433211232213---2112------51311123444345444-3435544454344443443416112124343424333333333322233221-12222222222211-2-----211212413222111122221111111-113-3-525555463541424132321111111111249333335134222232332222333--25221111111-----1---------11----111-11--1---24744141112121 ----33--21-----73555342664622231222122222112223226564723423434212125211213-42233322311213253323--1133-2412-1639BMADD74353565GC6C4EU7-97D3475E477646423663E5B68722845233421H3354-351N1--132123212--43224 * b.92.1.5 N-acetylglucosamine-6-phosphate deacetylase, NagA
[ 481] 11-1--1111111121-122222144433353121111111111111211112111--11-111--11 2112453444343354445-4333454444443333445625263333343353333422333445747541222211-13-32222244531411-111434343432-------111----333333353334222231115253543342233333333433245633333333433332222221-334444444643464454225534444333444433334342333333233333333332331------2-1-21----2-112133311121113112222222222211222111111112--333---122-13----------111111112-3-122112443112--222112-1122222221----222213222221133243333332-22222522222-2222222322222222211422222232222222212212123-----------------------------2222222333323333342222322333342442222232222222222222233323233342222222212122313323122232322-132222223322245222122-22222223222422322222225432242223333333333333343433331-12232-1---164453624455455544-4444455455456444446445648634444454445444444544433342-5666665565652212221124443223333333333333342343334323222346766433533234233222222222223445444446545544332333223222322-222222111-1---21------------1---------------11-1-1212533 33-21-3-3-1322235564454976A2222323333756676233663456443433456523432213224333212335543245344454544322244333-18376544AD455566264854BU6-73933444355235613443623326-1437141123511653333U53453979B2D333A6445 * d.161.1.1 ADC synthase
[ 482] 22---1----------12------322223323222222322222222-----122211222122-22 2221443444425354455-5444555555555555554434435443343433454433445644444443333333222212222244222422---23222222221-------11-112-22222222222222221112211111111111111111221112121111121111112222222323344444444444444432332444434343354444444223333333333333233333322233212322122333322222223333333322333333333333333333333333233222333322344222222232322332222222224221222222222222222322221233221111222222223333311111111111-22222222123122222211111122141121111111122222222222222232212222222---------------222212355221112433434222222222222232232353412222312223242223331221322222222222121362321123222222323322232333323222222222222222333333322223212222221233122333224322122321322-2221111-11133333323333333333-333333333333333333333333222333333333433333333333333223333333333332212222223344232223223222232222222222223222232222322222222133222222222222222343332233211222222221212222122223311121-1-2-1----2------------13------2-222222221123 2211223-A44-2323542122232433223332334333244342334442232232223223222313214134688924422322246255343322331424-2317DB99H75456566674M6b*D-DBJ4564A576625546653F6636649I61333622535832122a2222151263343668757 * c.1.5.1 Inosine monophosphate dehydrogenase (IMPDH)
[ 483] 1--1-2----------21-----2322-2233121121----113151---2-12111------1--- 112-1411333323-1122-23--1-222221133312311222443321112252111-543321245412---332--112111115563-533---3115323314--------------132313-1363-13232---53211111-2222412121422-1-121---111-----432222251354576866748678863366558781423534355441A8244444444444444344544233223-3323211221--311433233212223311111------2222222222222455532555215243-------4-537--266643221511-1112122123-33323133-3211------315542132224311111111111-56437341351-36633374343311-1-425313454411111111111-11211----------------1-----------1121--221114333331444333215554242324425113344222241324-21261--3-1121-111-211332423134111---12224232-32412C7321--21-----22133323221--241-442132111233444544544443436455----215------22341322224255532-2222554243253222224323553334555555535555554422332131-311113313211---------111111214444242-22212--23332322-11211-1112112333232111--------134465555575454-21-1-1-------11252222232---11-1311------11-1---1111---1----23222121113212 1111316-42255758A975A878686576544977655664565536A97976695368772213231334224311123343154233C3A764444414553617EBR5253653344353DD396Kj9-A4C253272654363454358367696797A58CGDEH479513429314711--25229555486 * d.159.1.2 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
[ 484] ------2222222222----------------21---------232-21-823--------------- 3322442444444454444-44444544444444445454245442242---454445--4442865774242222442252-22222433511122--2374245544--------------15554455545522222---2122322232222222222322222232322222222222-22----22-222222222222222-2----222---2-22-------32--------------22222--5-22-4---554432-22542-------------------------------------1--------2-2223-------2-2-344-223--223---53HA243222222221-2-2225555-442444667655555555655555555415754486445415444555555564444444845444446666666655544444----------222222222222222-----42444222223223233333333433333334343222-222252233432332225322222223322322223471--1-1---1----434554523445355-2444444444442222222222544433554422345345454422344445433423--22223------44664454444442444-4444544444444444445545655554444444555444444544544455-522444444444---2-----112122323333222213423222222222232222222222422222233223333332132-447555555565522234332222222--2-222233----------2-----------1------------------213225212 11--1-2-522-46223553552514533335357464344453331433648653443433544345256757533454533343232122313712232218581-1-4BF66A83333436565B4CK4-63454434435223254414B768451225742-A21--27-1112D32123F77C4A232----4 * c.55.1.8 Ppx/GppA phosphatase
[ 485] ----------1-------------1----11------------11111-111---------111---- 3344433333343343333-333336333333333344664556333342233452343333434336774233333344444333233333333331-4335433342333333334433333333333333334444411144332244332223333333133334333333333333332222333679BCECFEFF7FDEGGD579998EFG665565434443465455554544555545323535434554543422335544344444444424444333333333334311111111111113333334442576B6444444454664765777656245562466454343246665233322544321232233213322211322222222222-1111221212433333222232332133333333333344444444463333344331-1111-1334444443443333323234433433334444444566665555666645445335433433543334434324333232332222222222442234343343333333232333223223244223333333333333333333333343552222222222322322332222222222231-3222212111142224332333223222-3232223233322222222444232224444444544434344422232322232222222222222222222233332222233322232222322234333334342333433333233332333332323323323242222233342343333333433334343333333444343334221111--222122121212212122233233333333544 -------1--------11-----1------1--1--1---------1------1-1--1------------------------1---1----12-------1------1-2----111---------2-131-------------1------------------------1--11111161-2124112-21-11-1-1 * d.175.1.1 Penicillin binding protein dimerisation domain
[ 486] -------------------------------------------------------------------- 548----------------------------------------------------------------------------------21-JHMD-7652--9A365A67821------1------5554447236-7----------1212-------12151122-1133--11---281-1-121----7---------------------------------------------------------------------------------------------------11----------------------------------------------------------------------1--------1361-55433745635VKQACDJCEFD889A8BB9BB9-558656BA7F217984555677648C3633463222312444444443332-171FFOQOHHH212223443233332244335-265323221298898845664777766664768A6845123432741239333-34-4522414D2265212222-B5-13-2-221---19995869753333945-1321222221212----1--111291177157CC76439A9B986A78888A9F7DG---32351-111156596946HG8686976-K56A8A98D9J9877777766567658BBBACBBBDBBAEAAC586365664-877776777777--229A998857726735333435234321323444443646748555544454444343221111121112CEDB99999IF9B934655553423222---411----1----1--11-------------------------------1-1113416 ---------------------------11----------------------------------1-----------1-1-2-1----------------------------1--------------1-1--3------------------------------1---1---1-1213----------1111-1---3---- * f.4.1.1 Outer membrane protein
[ 487] -----------------1-------------------------------------------------- -1----------------------------------------------------------------1---------------------------------------------------------------------------1------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21--845-2---667333116224223473324163151313513352255957434215363252521554424573673457522124DB35852245154673-872ku*ioxgRTIFTbQ**IsT**t7*l*LZNLrSgmWHXRPDjOH*SiWXV9LDKL9DJkNWXJN96-231I3121-267534-2-11222 * d.217.1.1 SAND domain
[ 488] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------21--11--------------3---2-----------------------------------------------------------------------------1---------------------1---------------------------------------------------------------111-------------1---------------------------------------1----------------------------------1--------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------- 11--95F---1-46F33446555555654456755355453664355456565C445456566454443544445553555566344446B6379B5445245GFG2KD9NcgZdbgNKMILOOwdJkK**b4wW*HNKKWKOTFGQNJIXJInPURPQCHNBDEB7E6A7AGDC3422733328R***5**55BICG1 * a.4.5.31 DEP domain
[ 489] 21-1-154456555641133211431111122----------------13321----1--12112-11 123351-1221-2-34433-332256434443333338C7155232221111133311--33524694531--------11141111111---1-----1211121212---------------3322233321366666---23243255333332223222313333312211112112122232--131133332333234333453111133334413--------21-----------------------1121----11--11---1---1----------------------------------------------4-121111111212-112211131-1-1--2-471121--42--1-11-323311311111449673366675545455553457-67765D695841755556A657867522176644565553333333333342326-----------------------------21261288788A99C9B8777888EC787776CAD9B992566698666C6A78B657533246333444433367715834445564666-322112222776747232--112211212222222221111155211241212122222212322222223232---5555------33112225334545555-355555555535555555234321222222222222222222232233333--222222222222---1--111-11142556222211-222222212222222243516666575455557444431212311111113222222222233222222232222123-222233--------1-1-------------1-1----------11---2---321- ----332-851-2323553453455544433333333433233334444456674344344423324434225243313334446312147453326452332433-35573445453211334A51429K5-3371321323412324332133342577443322525335342333a3332242374335487652 * d.58.32.2 D-lactate dehydrogenase
[ 490] 11----------------11---11--3-1211-----------112--1222--------1-----3 2B81M-11--1---C9744-4A115G434443CCEDHIUO-B4E6H37-6718AA227--DIA1C5GFPF11---4211-1-5-----111-----1--25135F25-51111111111-----11-22-1222231134---63E3243322122-1213241-61389---1----112-34511--1214A9B9BDAD59B9DC9552244A8C2-24627244222ED-33352434433344134345-2--------111111--12-1-2411122224221313221221222333232433234221-12222-313511132331522322----4---12-4--31----2----1---11B-1A89B----232C9A11-3-3-478677665666-13241835AG6-I776CD9DCDA9656381E553421462222222212321-53-----------------------------137JA1123187BCBC963442AA964663-3D4A75D2--575315555572E23422415C2-1-----1-5-113222--11123111-24311111-44558A121-1------------------1--12335-511728636777765476673724836---2--4-------133111-11-----------1---------------653431311-1---1-111-1--131--11-11-1--------------5-1--1362332928111-----------11112113---2277673546521424333----------1238635537447ACA766674361111--2-434455--------1-1-----------------------------------3C11 1----12-11--13163635452452412111121122222112131114121212233112--2-1-----1--1---1-11---------31-3-----12----1D353-7124222112134242CS4-331-2413222--11-2211321117----12-1---3--521-2171112333372445162214 * d.32.1.2 Antibiotic resistance proteins
[ 491] 33131122333333331132224411211121--1-1-------1-225-1111111111----31-- -231-1--11-----11--------1----------2111111111111---121111--211-2113111---------1-322122--------------2111-21--------------1-----------333331111212322212222211111211232231-----------311221111111111111111111111111111112111111------111111111111111111--11---------1-------------------1--1-------------------------------------1--1-1111131-1-1----1-1--------211121321121--12-1-2113221--11-122221111123111111111112-24423423151-211122222312311-12314444326--------2----112---------------------1-------11-3--34333333434166763313666655442323312222232221461412221111321111111-11222-4342121111111112111112122124234---1--11------------1--111111-23-2222111111-1-111-1112--1---1322----------------1-111-------1-1-1--11-----1111--11-----------------1---------2--------1-----------111112412-------------------1--11111333325442242211111--------2111-11111121111121111111------1-222322------------------------111---------12-11-2---11-- 48446442E4515473485454465454456665455656686444475645545555556465557536675367556556666733398848AC787688678726V7IGIJJEJDCEADGEbPDaD**O6ZKV9EDBICGIC7EGFBIB6QEECEDBBA8A8FBE6AADEA74EEBm9B8BCBDIG4HBBBA9B99 * c.42.1.2 Histone deacetylase, HDAC
[ 492] 11111111111111212111111241133122221111111121111111222111111111112111 3451511111111137544-44115444444346578595221133231211353111112241435354111112221122121211111111111--131325331311111111111111321121121111111221111211111111111222222111111122111222121122121111121211111111111111112222211111132121111114311111111111111111211111111221211111222212211111111111211222222222221111111111111122111111112131111111111121111111211122111222122222122211111322322711111346466333353311111111113-22223222462127736696765934121223333321111111111222121211111111111111111111111111111113342113122223222311113235232211133442111221253434232422124112112222222112342212211211113111222111212436333112222222222211111111223111211113212222222332122222222222221-11111-1111122221222222222222-222222222222222222122222221222222222222212211-1222211223322323222111121222222212122111222122221221222121111221222232454343444341111111112222233333122224334344222111111-11111111111111111121111-111111111111112111111111111111514 67458651I66655755576878876755556567557777677665566665675556555453433-434334242443333433446745665545763745628HBC968B555746964JC7F5Eh9-86C86575479477756676B3A8598GQ958J7431F7A582554Y54466677J5A56357858 * b.40.4.6 DNA ligase/mRNA capping enzyme postcatalytic domain
[ 493] --------------------1----------------------------------------------- -1-----------------------------------------------------------------------------------------1-----------------------------------------------------1--------------------214-------------1---------------------------------------------------------------------------------------------2-------------------------------------------------------------------------2-----------------------1------------------------------------------------------1-----1------------------------12---------------------------------------------------------------------------------------1-------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11------------------------------------------------------------------------------- ----125-----11311112232121222211222222222222211111111111111111322222122222222-22222222211131122222222-3345-8C3XmwohtuVRTPZYa**Q*O**zA*j*WZbYoRagWOabXSeZS*ZebWYBJDFHIGBSBCODIPD21117111116436154178CDC3 * b.34.9.3 MBT repeat
[ 494] 112-1-------------------111---2-------------11---12-1-1111112------1 -12-12213332312--11-11--1211111-12221364-1-21121-111355331--11--216122-1---21--232-1-1--1112-3111--13213412222222222222222221----1---11-----------112111--11--1------12322-1-----1----122-----1256686756757777774255547754365422------41322222222222222332254-1-11-2111121112211------11111112---1111-11---1111111221111122111222--24155555555656-311544423-74-2---2122-2-3--112--323-133341111131953---2111-----------1-3364383512-232211132111142111--3------121222222-22112-122312111111112111121111112124-224314----C9979B445532258545534533356512445113224213421111111351111111111--3--5-2--1233---2111-1-1-22212311-12332333331-----1---12-1-1-772322331325888956B777676B8697---2---------74445544555454444-5434544454545444445666663326755666666566656444354441-6444544454551111-----343312-232221211222211128888838223424454567826689343222222222214559454437566533444443333333---711111122212111321----1-1-2--------3------------------3-2 -----11-31-11131312133--21-114112-11-2131221--112211222321------2-11---------------1-1--114234132133-12314-173BLUKMGE8967AE8NM4HAO*A-DBO7968CAACA48988973H8BG8E59D4HB32544D87C5-412A---2341132357-HAHI- * f.49.1.1 Proton glutamate symport protein
[ 495] 33348744333333352334333311111111---11111111-----1----A6565554---12-- 111-112111111111111-11--111111111111111112111111111-111111--11122111312-------1111------2313-111-1-11111221212222222-222222211111111131--------1-22122211111211111122-22211111111211111112211123222222111131211122222212232222122222234522222222222222221221223232231223322221232212223333333334333333333323333333333333354333444222321222122122234223222224212231122232111312222-11111222222222322232222322222222122222-2222222222222223222222223332232222222223333333322232222--------11--------111---------232322222222222223333222233333222223222222222222222232222222422233333422232221112223332223321212322233334211---1-2111-1-1---------11-11332121221224544444444444444454--11231---11122221222223223222-2222333222232222222222221112322222222222222222221221-122222222122--12111112211112111111112111-1111111111111112111111211111111111111-12-1122222222222233111111111111211-2--------1------1---11-1--11--------1--------1-111-111-421 588676B1RB9744A546354484443344433553545463333253455658434434443334432335343333333434344443444343433332475535L7Q99A9CAA877797FB7C8g*F-BAH6577A77D567776776D7A98778EBD859955D29746799e9A7637CHE5CH8BB9BB3 * c.66.1.38 NOL1/NOP2/sun
[ 496] ------1111111111--------22221312--1--------2-121-5432------1-1----21 532-332233222233322-24--3522222344444344231224222111353111--2242213252222222222133------43212111---2734365533--------------21--111112-3-----111114-------21111111122-1131-1111121111211-----1-3-323233131231212222223523221222228443342342222222222222222222D112222121122112323223138421111112111111111111211112111111112115446112121121111111-1-221112113112221411322-13231111111114-35223----2323344222242222222221225-363343334522555344253546243323222222222111111113422131111-1--------1----1-1-1111----12232-222124256334133333423333322622222-14221312212353123211152111111111423321172122212222312121231341131123221-22-----1---------2-22133311352323212347323444222223222----232------23112322222222322-22252222232222222225322212323122312314433232-1222211-222222221322---41-111644322232111121-----111232352112241-337324232224343571-1111-1-1212311131522323223423232------2-11-111--------1-3----1-121111122211121111131-1-1-1112312 12-1216-F7D22143575554444345532334445454344333364543544544444532222212212234212232222233335456333444-44332-5I3ELG9ADK9988799SO7M8j*I2NHP8998I79D87B986999M9C7995275A684B46F34933583M44465659754A8337334 * e.8.1.7 Lesion bypass DNA polymerase (Y-family), catalytic domain
[ 497] ----1-------------11111-2----12-------------1-21-3411----12-----2-5- -1--1------1---------1--1--------------------11-----1-1--1------1111-11----111--1----1-1--1---------------211--------------2---1-1------11--111---121---1111---------22121---------------11111--1-------------1---11-----1---2-------1---11111111111111--------------1-1--------------1--1-------------------------------11---1-1-21----------2-1-111----224--2---1111----11---1---11-------1-------1---1--1-----------------------------1--121111-1-1-------------------11--1------------1---------------------1----------------------------1--1-1-------------2----1-------11----------1--1------------------1----1-2A-----------1----1--------------1-------------------1---1------------------1-------------------------------------1------------1--------------------------------------------1------------------1--1-1--1-1-----21-------1--------------1-11111--2-------------------------------------------------------1------------1------- ----1---3--1311-1-23--3-1--1111--122112112243312-13233-113--1-211-2-22-1-232---211--1--1--1-113---21-1---1-16HKZgfRi*XTWbbpc*wZ*U**k-xe*QdVUsWV*eYYdQWkXN*SZVVSA85H8AChiRgFFK44145-5--1314B4F1F11312111 * e.1.1.1 Serpins
[ 498] 11------1111112---111---2111--111-1---------------111-------1111---- 1223622222233262344-422243434443444435764546344433335564452244434377644-----------3---1-3332-2--2223534333334333333333333332---1----12-45533---421111111111111111112131131111111111111334331--324555554553545554575564655455444422222252233333333333333344432-2-22-1---2211111111111111111111122111311221111111111111111211111211112-2244333432412111-----1---3----21----1---11311-13-2422222222225334233233344444433443-225225233422233232643354223233342222232222222222223222222222222223222222222222222222235832232233443443333322253333253333333233332222222444223221112322222222233322-1-3----1111--323143421333363-22---------------------112223323323344434333343333333333441-2432222222232322322442333322-4232333222433222223444223532222232222232223222222222232222222222222233333344442242322222222222222243334232223244543333333332222222222222122232222233233333333344422221111222232----------111111-1-11111111211111-------------2243 33--945-A33-3343333643454544433335343423333433434444443353343332222222232222222222222232226336333333434646-355A4666564553545464A4En4-94E4444554744444544664P53449F57545434C55666644w444458AFE3C665A6694 * c.43.1.1 CAT-like
[ 499] -------------------1--------------------------------------------1--- -------------------------------------------------------1-----------------------------------------------------1--------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------111---11-------------------------------------------------------1----------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11111-------------------1-----1-------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------1-------------------------- -----K1-----EC-1316-------8-1-------2-----1---2-----6*--3n-------1-11-1---1-1-----------1RB339K*--11-*-12--1B-AiklDxE88777A6HIALBZ*K9LCO97A6IEEM84BA57G69R696DQq*b**5*D74159KD4-Nt2-1-22-6*g*EUC--**T*- * c.55.3.12 Hermes transposase-like
[ 500] -------1---------------1411121--------------22-1716A2----1---------- ---16-1-321---11111-11--211222212111-55315-C241111--2411----753-7-55121-111-----2---11-1111--11-1---41---24-1--------------568469645A15111-----4-*hhgdbMGHAA655666LKJQdisY474444474444--1-------222423433-43343321--12333---312211122168----------------1111122-------122----1-1---111---------------------------------------------22593333333733131--22111--------112----1---------2-29AA8------43-2---1112-------------12215322113-2221111212112-128421----1------------1-14E1333333343344773377766465433331121---42-C1111--37BBB--1-BBBB-7-11------1-1-1---14--H--111----------------11241-4----16----1-2-5262211--5l41------1-----------------1--23--121-1192111112411112143141---4-1----------12-12CB-4---53-924661-655B2A331542-----7--2312333434223223531143323--44444424654--21222222222--2-3---11---------1------11--52322213122111-1211----------1313-----1223311--------------K-111122--------11---1-----1-----------1-----------------1 931-684-A34---2D1-------1---11111---1213123----------------111-------1--2------------2----2-1-----11----21-2*HU958B962434353C54F7KhA3A963273435633432444273843P4447AP633122-2h-4559*56643D97N-CA43----2 * b.80.8.1 Pentapeptide repeats
[ 501] 221153515768664FC7DE5-4A2---3211--1-8-13241622CG--D28542478351--3--- 2231412111211-5---------22-----1-1112-14-24423-211--1-------322112212123111322-133-132232-52-8-------11---67----------1----6113325-25--1CBNV1-112-4B89BA21235--21-45141111------------2-36B23-2324545636625655473-11-14454312321------54-36-3-----223---15--1-1--------11------111----111111111-1111111111111111111111111111111-1-82-2411122123171-661---143-11151458556B16A7679B-123C25221-----222121112424411111111111-12122363121-4552324432231112212311111112222222211113344-----------1--111-21----------1113-122113555533222222222222234322232-122363232454243346332333112111142264331421152-41111-549472I462122163121-1111-11----------1228331234361212263112134321214634135---5353------13213121111111222-1112221222112111112333135532112131211112124211111122-222222222222---1222223432425222223421222142223222422--15332132221322224142---------1211122222113213112222221-1-11221222243--------1------1---1-1---------------2--222442121- 423355--C365114125521235243443434443355555543433444355333353331-1----------1-111------424222242322223-35421596*776659242635395393GU8174A34345354456433533E5636432495232833767231775F233536779596437AB82 * d.218.1.5 Catalytic subunit of bi-partite nucleotidyltransferase
[ 502] 11-11111111111121333332-22212122--2111111111112-21111-22211211221222 2142411422221243333-33113233333333334534133316511342212233226322223322211113222112112112213312112--1111211122111111111111111322222222231221211133311222111333333321211112223222223222212111-1121122222233133433342221123311122111111113211111111111111111111122133111123411221111222221221111122222223222221111111111111111111111111123333333313111111111211112211221321221111111111311633311111112223222233322222222222-23222222222132224224433222121122111111122222222-1-2123211111111111111111111111111111311221333133334333333333443333233333343221221324343234122232223222222222224331121211-1111112333332434224224222333333333322222222231332112212222212211111312111111111111-111131--11121112211111111111-1111111111111111111111112222222222221222222311111111111111111111111121111123222322211111111111111133333332223255452542322222222222222222222222222224234222222222211112121333332111111111-111111-111111111111111111112-11-----2421 2211866-6221446567678775755666777888865666776766755576676667475555351344345664564347545438DA69BA757644676828B4I598B6644765648B496PfA-87C435595595552535647564778666B674F9CD55953767V55357899A86B5787875 * d.13.1.1 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
[ 503] 1111-11-111211--1121-1-1--------1-1-1-------1--11----11221112-11---2 2341333433323233633-33445233333433333333323322233442333333224323653443333222223223411111334323333--333445353322222221222222332132222122322333332443233343333222223342333344221322321232321132243433333333333334334443333333333333333334222223232232222233332343333333333333333333333333333333333333333333333333333333333333433333335333333333333333333333333323433333333233333333232134244322222434633234444522222222223-22222222233222233262224433223232222222322222222222223223322222212332322322224222222212222233334444344444445545555533343443233444333333333333343444333333333333453333433332343322343433333222222332122211111121222222211121333333334343333333333333344333333-3233333333333433333333334333-33333333333333333333333375333333333333333333333333331433333333333333333333333333533333333333333333333333333344555554444444444443333333332333323333333333333434333333333532233221221112133222222-212122111112221222223222222321223 12-1221-2111-12221123322222222222122333323321221232232132222-2233122121322122122111122112132232212212214111224421113-332133231341382-21423123-2312223232311112121124123213412222132I2222221141312152322 * c.55.1.9 YeaZ-like
[ 504] -----------------------23333-322---2--222234C-5I-2424-2-2122-------- 2523------------------------------------6---6---3-----------113-3---------------1---3333-------------------2-------------------------4-36656---23DAFAFF24455------677-66E7--------------1-----243--2-22222222222343343222433433322222232--------------------------------------1---------------------------------------------------C546B444444444463554---43C--44383445327526233883--85-B779-----229BE3327B22D------------5565575B23--5339776777663-5-3-2-888825---------2552-89A------------------------------2333352222555555C666655666668385639999--555D5555725B55AB85569A9-------7432AA7B55638A7PHAAB5KINEEFIACJJKJMA524333-3333335555555556839---B9-B8B4444-8999986688878966799--23668------33332332222222222-2212222222222222223---3322233333333333333332-2-22221-322222222222---3---------33J28---------------222221222229CCBBCCCHBCCCC8HHH---------76667EEEEE776AA98ABBBB9AB3333--E57744545555555533--------------------------3-33333333-5-- ----------------1-------1-------------------------------------------------------------------1---------1------1-------------------4A1-3------------------------4-----1--------1------------115-21--1---- * b.40.7.1 CheW-like
[ 505] ------------------------------------------------1-1----------------- -1--------------------------------------------------------------------------------------------------2---A---1-----------------1-----------1---1--------1-----------------------------------2-------------------------------------------1----------------------------------------------------------------------------------------------1----------1--------------------------------------221---------------------------------------------------------33-------1----------------1----------------------------------1-----------------------------------------------2--------------------1------1------------------------221----------------------------1----1----3------------------------------------2------------------------------------------------------------------644444444445---------------2----------------------------4----------------------------2141222-----------------------------------------------------------------------------1-- ---2473-1-----------------2------11--------111--1211-11121-----------1-1-----------------11---11-------1---2-8D*****qYPQWcnT*oU*Q**q1wa*ZZcY*devUUkSOLpTS*Z*QX*32--142171161221---1-111---C4b-F-1-12321 * b.11.1.1 Crystallins/Ca-binding development proteins
[ 506] ----------------------------------1----------------2---------------- ------------------1-1---1-111111----1--------------------------------------------------------------------11-1-------------------------------------------------------------------------------------------------------1----------------------------------------1-------1---22---------11-----------------------------------------------11111-11-1--1----221-----------------------------------------------11111--------------------------------------------------1------------------------------------------------------------------------------------------------------1----------------------------1-----1-11-----------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------1-----------------------------------------------------------------------------------------------------------------1--3--1------- 3311HGA-lM95IGVKOMIOMNOVPROKLFIHHKNEFJEHDHHDHJIIIMMMVNMLIHJIJJCCB7AA4A76C9B45355999AAB486KdKOIMJHFHEFDFcZZ1AdEE8B687986876C8EI6F7JkC1E9I7778D89C859865H94E8FAC83677EB79DCFI9CGB6B9H*JFG6AJBMFKB9FJ8ABAK * d.120.1.1 Cytochrome b5
[ 507] 223433324333443342533427323323333212233333343244211-1267666763346-44 43545111221-1-31111-12111411111115353357265535232221336343--248143565461111111-11-45444433331311-1211223223321111111111222224322233333323334221441121223221122212221232314-1211--1-11-22233-12323333333333333333434433334332233312222143111111111111111211113---12---1--------11-1-222111111122222222222222111111111111122211-2222132-111111111111322-1111211-2-13245225--2441121---233211221111138463173454522222222223-556446445732433442554445452213432222547--------211-253311111222111111111111111111222312421195594222223244422575455322284DA9124324424573344534331222212222222236422DD734861575531645352733345336A51-222222221-1------133443112211312112232222222222222322221112224------54333445556566655-55555665555654545553343344343333243334343343334333431333333333333111122222332331342111111-111-11111111112111133333121112221112122222122213234222223223322323222221111114-221111------------------------------------3-112121112211 33--334-62142224643334546453344444754444334333454444432235444432111-11-2211-----11114112246364334542234664148445944352232243663228O4-415223322234222352124-422733725322724546443221H11133626B5555434535 * c.2.1.8 CoA-binding domain
[ 508] 11112121122111213111112232222323332223222323224224234311111111111412 2331212211111112211-1311231111113121513111131111112111111111132211131212111111112111122111211322112143412311411111112212222311112111111122211143211211121122111112111211133122222123111111212121111111211-112311111121111111221311211111123221111133212132124111111221111111111111111112211211112224111122211111111112111111121111112317777663565148724321422411111211211111221151733112111111111141111222112111111121111211111133111111122111122111111111222111111111111121223211111111111111111122111112232131211111121222112-1111121111111211211111112325212211122221111111111111111221113111211212131111111222311341214--213332224212323122132412221-12111112212211121112111111111111111111111212231111111121-11121111111111111111112111121222222222222211111111112111111111121113111111212411111121111111111111221121111221111111121221212121111111111221111111211522311111211111111272211124443243211211122-136513145242213167311233212222112 co9FJK44M34488534745546837655687A46444645546547337655645543355467364-47555555353567447344563484B354448544C499BDAADA85344444379683R*5-7554433634654464353454545949JF8H6C535C59AA5446i34655ZCCD4BG54A6568 * e.29.1.1 RNA-polymerase beta
[ 509] -----------------1111--1222223221111111111311111111111-----------122 1121333444422222222-2211222222223222425413333233222322232222232253562522111211221122222222231212-112232432334----------11-1122222223222233331114242222221122222222222212212222222222222222221-3245555555545555553344445553352322333333322333332333333333323311-11112-1-11--11-2-1112222222333211322223222232222222222222211222111123234111122222221224222112-22112233211111222112-11222333411111334333233343233343333226-44544534363-6445454354653325345565664452222222222213135-----111--111111111111111-1--23222345554555456733334453444434534433322335332222335623323323222222222333345225333432353332122232222443423232333322222322222222222222222243232232222222223222232332331114333------22442222222222222-2222222222222222222222443432222222222222222222222222-22322232322222-2111112222333322221321222222223332332222232222223222222222222212222231222222223222232322222222212332-222222----------1-------------------------12121111112223 111-223-85433335687755669753433343435443533333456997E97644435442224243322233313423343322336563553234435559-5C324422542242232A52728a4-55A2242544312421141292314436133343122A33314563X33464G9CCAE97872634 * e.17.1.1 D-aminoacid aminotransferase-like PLP-dependent enzymes
[ 510] --11-------------------1-------------------13111--1---------------1- -32-22232226634--11-13--2211111141314786-22411-2-11-241--2--3342423377--111-------3--1-1--------1---221-2-22111111111112122111-213112-2544-----3-633-1112134121-22311344251112111312112-2----12132121213212222321-4433223-1112212222234-13333333333333354413-11-23-12-2551132212-1-111-11----121---111--1-2--------------11---111--11112222222323-1--2111211--11-----1--321--113--21--21--1-----32744--13132211-11111--1-111112-1--3-111---122111112-122-----311-----------2--23----------11-1---1--1---------22-1--11224455633233277-34335-338-4233--4462321113345-119----2--------21122214251111-213211-2--21411233297-1----1----------------1-----663123-12133343334624316242237--12414-------11--1-1221121211-211211112123111111-131--3221-11121221212113-11111111-2--------------6-----2544-5522---111---------65565251453355443243341342111211111111-3226322322343454434332312212--2-887799-------1---------1-------------1----3113312111-21- 6224472-4-5566B8993DBA9CDC9A457769896747565576AFDEDDGCCGGK9C86A756795787478985999545662216889568334527588A-5DFEB654BC46458757B294Id7189C654363573347678669A6564125686758454HJ5378A6D97653JIFL6NF58IOPW4 * c.69.1.18 Bacterial lipase
[ 511] 11113211-------13121111-211121-1--1---------11111-1---11-233-111---- -122221222222122233-31113233333322221212-3324A531331223435--3432428888311112322-114--1-22371-211---1412172926--------------111-1111111111111-1-12322-11-11--------11-12234----------11323-11222246655555566555556355335642224222222222673555546456555556344433323322323441133322532322-111---122111112112111111111111111211---111224-213333333233-211223151-1-212--22--1-18--111-1313-243321111222313111111221-111111112-22222322232-7776555675331134331111113232222222221111232------------------------------21212111112232222333322224433322123223--333222223132412111---21-------11212252222112-23221-1-11--13-322231-1--1------12---------1-21---22-223122322333333222222114212---21-1------22232112223223222-222222322222222222233333224222222222222222242212222--566666666666--11111112222122211-1111-1122-11122222111212244442324311122564222222222-212322222323231144357444------1-222233---1-111312--------11--2111111211---1111111111--1- 1222431-9443345657635567766443545656A6667664443623576845554333333324223345234254244334222351547353342623131266CED88FB88A4667B98F9Hl81C8C6697C56B657968875H7888A62668794B13268693952M45274EKLJ5K94423421 * c.1.18.3 Glycerophosphoryl diester phosphodiesterase
[ 512] 11-1--1111111111-111111-----11-----11111111---1---1---11-111-111--11 3362723444342243344-432268434445344455BC234533544433A5732222857355678623333333511112111122131111--1111413131311111111111111122122213223222221121145554353322111121233545442121121111122222211112233333243232333331221133212211213444441211111111111111111111222112132-35611211412233212321122-11322223323231111111121111111111222321137222222242512111111122113121211111121112111212133333411111439783253455423222222226-45745835452132213446435637232232433523322222222765233621111111111----1----------11113114114333377756544444557655554544834642323355243465373233342232222222233432422122221113111123322233133532221211211111111111111122211155229232223223433343533333333333212632322233343433543334344433-3333344333343333335676433226455555555555555323233332233233333333322232222232224223322233223333222433333222225233333336322543533222222222233333333333433332222233322222231111122--------311----1-221222111111211111113111231213111 12-1411-412112122344251455633321113131111111225232447533311222213211112223322-222111123213722333768212123211823563522221223333243HV3-43343335225-2243242162312213112262623611512111Q2123254563432351111 * c.36.1.10 TK-like PP module
[ 513] ------11111111111233333-33333-22-------------1--------11--1-----1-24 3382433433511141145-4711434343438658373627453423433264633522588142566821111-11---23-1111------11----4-1-637121111111-------2-----------22223---3222121--11--11-211-2-1215111-----1----43211----2311111313122233222224322332242212222121321111111111111121113221-11--1-2-1221-2111---------------------------------------1------------111111121-1-11------1-3--4----11-2----------1--5-29566222122368B3458788844444444436-5865B664749145565476564476466957646566A2222222243333454222212222222-1111-11-1---1-2-394471233135585555333344754443237555A7713666574636665A2532213121233333324334341211-12124321123362-4-38A59CG422322-133331---------2--1121432242724474565627B544655A75781-132-211-11131223242223243422-22223332222332122234452222455665466545665655222222211433333334433-121-----1111133152225241222221122222214242424554455443463354411111111134457333436774456335442333323112-443333----------1--1---------------1----------------12-1 -----11-4123324477664447369443433544532323343355776768355244641-----31---1----11----1---222372321121234122-5A36342153612432434151Fe8-56A154252331-31112116322243-2236215-1545981224K3226446C56544541315 * c.47.1.13 DsbA-like
[ 514] 11111111-1-111112111111112111111111111111111111111111111111111111111 1222211111111122222-22112223222222222222223222121111222111112221222222111111111111111111111111111--111111111111111111111111111111122111111111111311111111222112111111211111111111111112111211112222222222222222222222222221132122222222222222222222222222222111111111111111111111111111111111111111111111111111111111111111111111111112111111111112111111111112111111111111111111111112411111111113115111111111111111111-111131111111111111111111221111111111111111111111111121122111111111111111111111111111111111111111111111111111111111-2221111111111121111112112211111111111111111111111111111111111222111322222222111111111111121222222211111222421122112223232222222222222221-1111211111132223222221222222-22222222222222222222222222222222222222322222222223231244434444333111111111111111112111111111111111111111111111111111111211111111111111111322222222232222222222222111111111111111111111111111112-112111111112112111111111111111111 6533686-I7643465789656475665676777556656666565A8557476567757678665565556645872775666567779E87B8f6777877C8744N6KBC9ACC7776476AB7F8U*C2E8G5675988867887588796879865B6GAA6778946I45687Q77575I8DC9CB7AA99E6 * c.120.1.2 5' to 3' exonuclease catalytic domain
[ 515] -----1--1-----------2---1--11----------1---24191-2749--3----1------- ----4---1111--1------1----------1-----21-1--5---211-6638-3----32---572--444B89---12-----3343-433----1--2211-3----1----------1----1---1-23343--142612121211112121111113112112111112112132622-----1222211311122-121211-1112-111-53------31CBBBBBB7BBBBBBBAAACC5----1--------------558-2288886664664444444444466666666666664--666---4221-222222332311222-34422322---2-742213---2---312-21-1111-----111113123112111111111113-55155423221-322321211122215121225355133111111114221135311------11--------------------4533-122121111121122211121121211111461-12223321111132212231113--------134334-361135323596A1447-2342812315225--11-----1-12222222215-----1-13232121-2-11-11-1111-1221-2---3223------11111-2-------------------1---------112-121-11-111112222121122---------122222222122--11-----111111512---1----------1---1---11121333222231121111112--------1----111111-12122411112231111--2-1111332222212252------------1------1--------1---------1- 5332522-C221648D68789676868786867A976BAA89B76589CC87C996A6566354544315335634412345557375539868BC96664R644G-4C35848D744876444EG673Fd6386B3B947957535256915I8546A1425A24B654731323474O5245789BE8F6444DLq3 * d.108.1.4 FemXAB nonribosomal peptidyltransferases
[ 516] ----------------------------------------------------------1--------- 359--------------------------------------211-------------1----------------------11--11-39BC9-C23---3623191A68--------------43443424343312243-----544244411223236431211CAE1131232222222-------22-11111122111112211-2211121111--1-------31-1111111111111112212------------------2-1---------------------------------------1---------31245---1-1----1-661--2-1--1--23-4414221-12--14---96L933621111A9CD9A33B886644544455557-4965797D264-94459B2B9C26763324164-423245555555538963B771111111111----11-2-------1-11312C-466336ADDCC69677788A986673CFBC887E-245642332A432524554546841111-1153476632643-42545334152133366459685755A-21211111-33222222243126AB3346569-725377773785676647A6781--4115------869C6567668778787-86767887868877777775C76B3644555455555545454956457752-633455534555--1144232677842659112221112111112676665423162AA8BF9EB5BDDE846655442442546A786444448A78BD897985552322--G-11--11--------2-------------------------------------AD6- ----------------1-------------------------------------------------1------1------------------1-----------------2---1------------1--1----------------------------11-12--1------21-------------7-----7---- * f.46.1.1 HlyD-like secretion proteins
[ 517] 33131243434343543-2324332---3--611321343333343655355512112222111-1-- 24533121111--154355-5B--4755555-88985355312423213---1141---143313263842--------497231313---1--------11-1--111--------------21213121122-32223122342121----------1----------------------22-2311-2-3111112-111212122144-31212343--222222313212212111111211211212-1----2---1112---------------------------------------------1--11------65-211111112121411122133--171-41VQ-525-233---11-13212112-11-1-66246363924222222222224-4374466664--33337444545573211424242343611111111411-2523-----------11------------------22-135537433434746668835666624344778614784443443446436423334341---2-21228661685323968545A177668462376763359489323243-5-4111111168454227421212-1-25466617C777667976C81--26211--111C876792CDDCCA8CCC-ACCCABCCCBCCC9CCCCBBCB87519CCCBBBECBBABEBBB875687991-75456666666611-11111111113254-55555422133233411121113124-57555244355647232---1------377A455557745433111111111111-131111111----------1--------------------------121211-2122-1 --------1--1---2--1-11-----111112----------------2-1----1---11111-1-1-------1---1114-2---1----1-11----------11221322--11-----1-11132-111--1--111111--11-1--2111----3-1-51---12---1------12--3-3-1-3---- * b.52.2.2 Formate dehydrogenase/DMSO reductase, C-terminal domain
[ 518] 22222222222222222222322222222232222222222222222222222222222222222222 2222222222222222222-242222222222522222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222322222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222322222212222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222212222222222211211222222222222-22222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 45222241D64233322343333332333343333333333333333333334333323333323333234223344244333333555343233333333436652452688566342453837B1G3Ai8-55G3443444853424153243646545355543A56444756354i54346DGMQ3DA2223323 * c.55.4.1 Ribosomal protein L18 and S11
[ 519] 2-11112222222222122212112222213111111-1111123221-1322-32332341212-11 1262422222223136622-24114622222444442233-111112212223232-21132113233531111111111213111113333-4221--1212121221111111111111111221131112322332311122223222111111111111113222211111111111111111222222555554542554455342232645235452222222253222222222222222222223223233222222223312123233311221222222222222222222222222222222322222222131234445455242251133331121131222883311224311112212111112-121-112111111122133443442447-111111218G-1988443767576321122775455455111111111--11111111111111111-1--1-1--1111111141232112222333333111113325212112344142211111-21111121231111111311111111111111233233331232222333232432112121321111111111111111111111-1111122422534334222233522224254245--12111------52422413333333333-33333333333333333332322211223222222222222223333222221435345435444---1-----1111115622221111111-11113222412111112232232125334111111111111121111111112221112323223332222111211111111111111111-1111-111111111111111111113211131111111 1111343-732143357535452656466555545435444445445545647824544444443333344334333333322244233574754444533337771354L664549244445485484Jq5-8523323634624442252274353359746464559D65A32352O3322345544571244654 * c.55.2.1 Creatinase/prolidase N-terminal domain
[ 520] ------2-------12-321-1-1-1112-1-2--111222221--1-112-2----------1---1 3242611111121141111-11111311111121213122331514313441121111212242522131221112112231221211113112112--114313322211111111111111221111121132233221114253532244433212221313232652221222221122111111121121323323332322214331133522133111111116C33322221223332212212211111211111111111111111111111111111111111211112211121131112111111211119232111111221122221221432111133122311314112221112415211212112117541234422422222222222-2222243244323111342222113313322423221112222222231133222221111111-111111111111111222222131234233122222422223338333332423335413332354543334543443222421212111543334134422631341221211111121444369331212111112111111111111111333325433453343223243332232342342-2355321-11153323423333333333-33333333333332333343434324244545554455555453333333331333333343333112322222555545553111211111121111222222222231786855363747646554433455243222444444333443332223333222222314422331111111111-------------2------1--11112122131221223 ----216-94433354-1-432476671111--4233111-11-21321126462325434332122-12--21222-2221--3211-111-311---2131121-1A3I2659974341495CD3E5Qo43DCH4454D47951442392143565J6345F5244-1369441963I233359578-62-1B6764 * d.142.1.1 ATP-binding domain of peptide synthetases
[ 521] -------1-111111--------1---1----121---11111111111--1--------------22 1221411-----2-2----------3-------1111211-21122111221342123--2411112323-2222222---11-------1--1------1--1111-2-------1------121-11------11121----11-111-1--11--21--11-3112-----------1-431----1--3222222321223222112211222121112122232211111111111111111111133231221111166113344422155433331123113333333333323223222322323331113333---311111111212---1222211-11---1-21-1----2-211--2-2-2111----1-312113111-2--11111111111-1221231122--122-2212322311-1-11122221-1111111111331------1--111----------------------1-32--11-12222221222222322222222231112--331-----1-1-2--1--12-2---------------1-1---1-11111-1-11-----111122-1-1----------1------------112221--1--11-111---1111111121-1--1----1--11132121322222222242-2222232222223222223655123212222222222222212222222231-311111111111------------------332212123131--1111111----2-22222332-22221113111111111-222312222333331111111---1111--1111221111111111--1----1-1-1111111112121-----------1--12-- 22--534-C53-333AA97665985A72242223222222222221CB7C576855611212331222125214155234111111--1843A23811126C633314C2IEMEJIFBA8ACEDLICOGi*G-MHN7CEBF9EDE8EAD9EB5ECGAGJ546FNIABG98O8DC2133-212-A7RZ**7hK42UNba4 * f.19.1.1 Aquaporin-like
[ 522] --------23-312B--1111113412131313--1--2-411-1-1--1-13---1211-2------ 14A-1271115A-616722-28--3822222--3621784--2D1124-2*134A222--11-1-121A1-----81---251--1--3211-21----11-----11---------------1-------11-2---12---2-Y911-1b--1-------11-26A1Q-1-----2-----11------3--1-1152A379C33A-21131A641423-A-733223-1522361111233-12-51435-3-6A-512-3633622412129AA2221436-112112224-13421111122322421--3A91----14152222522232j33211-431--1---1-42K311-111--23-22---333-------2411JX121--232322321226-53746625-8--75532-H23346511--911211-211999999993F74-5-1---------1-31------1T------5-121612--9335571C9G11112-282312341B7-129-22222-L21A72-122-621-2---2-----S69212-27-32-F-4123--122311-5A12-311-321112-----13-1112221-----21-a86A1-1--7-VBGB5B741453x23631---2--2-------1678143784422562-3-3465212864578277-8671-AE11A--32--1-2221-47769L25O2-9DDC7EDC6473--51-1--14134-----BDA-111321121--2-1111-7C9-123413--3-6-1425471---------322G23213X22562-5-51-5642-1---3----1------------1--------1-1------B-------24-C--3------- -----------1----1----------------1-----------------------------2--------------------1-------1-1------1--6k-----1----1------------78111-2-----------------1-------3-4111-21C--1--------------2----11-1-- * a.4.12.3 SPO1678-like
[ 523] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------1--------------------------- 111131--422111-1111111121111111211111111-11122-11122111111111111121111111121111111111111111111111111211112-1119111317UQKZOFJ*rQ*Z***8***gRTXgTk*cVUQDDrQQ*CO123221121-1111211-21--------131231211-2111- * b.88.1.2 Translationally controlled tumor protein TCTP (histamine-releasing factor)
[ 524] 5523346588878876123647488335644613-122---1-4545521534232421242114--2 4896B3-21112-259733-351168333334423224C5-6334312-13-644313--34412585651-------334882-2123311-2111---4-23C-731--------------1--1-----11164433---72--2---13---1-121-----122-111-1211--115353321-456BBBBBB8B1A9A9A9344424CA92248747211111C6244343333444434222321-1------------------11---1111111111-1-1-------11111111211111--------123254444455424419554112542-1322118642462-321213-212144326--1-1-39AA4214453522222222223-57658575445-41116635749534243636253343511111111-2212--1-----------1-11---1-----------3673-1111142252423333114343543622356841366586422745153115212121----------4442E69441-11422-12322432-26625774522111212211-111-111121222--3212317333-42222344522112-3146---1124------1213-231--11111-1--111--1----1-11111-2212112111111111111111113-1------1211111111111---211111----13721111112----1---133223112232-223213214121112322-111111-51123444443345543211111111111-131774644----------1----1---------------1----32243453451714 23--1-1-824434337447AA786B62222113342111111222644C48GA335235341212--22-11-2--1-1-----1---24172133243-11324-15672436442532234B22254F3-433232-4442123322433433321883-A222632A248226-17222212234444433112- * d.157.1.1 Zn metallo-beta-lactamase
[ 525] --------------------------------------------1----------------------1 ---1212----11134322-25115822222264443246-1-11-1--1--222211--213-227513------------1----------------11111122----------------------------------------3-11------------2-11-2-------------1-111-------------1-------------1---------------11-1111111111111111111------------------2------71111-----------------1111111111111-111111111----1------------------------1----------------------24443-----11777-244324356586464565-343126244A4-A442457767863224233A323264733333333223-1-2------------------------------126B4-24313845987444444479555537J596976-15332223342324932----21-11111112-1-1-22---11--1------------------12--1-------------------1---1--1--321523311222222221111122122---21-1------221--132222222212-222222122222222122123222-12-1--------------311111211-121222212222---1-----111115224111--11-111---2322221133111454444442453232221----------11311111223223211311--------11-------------------------1------------------------------- --22121-432--12KGYFPBFGaVXM7848674533444344554RLCFIOWVPKKKA6682---------12------2--------YiVGZQD33224983-2-28479242415A79658Y4853HnJ1D8A3824846GA58454A87162224DMN5C3HfGNNg1233111----111569BQ8H42BB795 * d.16.1.1 GMC oxidoreductases
[ 526] -------------------------------------------------------------------- 313------------------------------------------------1-----2---------1-1--------------------2----------1--1------------------------------------------------------------6----------------------------------------------------------------1--------------------------------------------------------------------------------------------22----------------------------3-------------4--------------------1-----2-----------------------------------------------------------------------------------------------------------------------------------1---------1-----3-------------------------------------------1-111-----2-11------------1---------------------2-----------------------1--------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------11---------------------------------------------------11- ---1IA3-------1----11111111221111211111111111111-11111---------11111--12-1-321221---1-11-12--11------21553-5A4jnolpdbYSSVXZV*wPxX**wDwi*MUaNkadeTGaYJM*JF*beUXa6JR9fC88Q6AX46E6-39CdADD111577-63-F4K2L6 * b.1.18.1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
[ 527] 1-2-11-112223214-111111-B35632B5-1--11-----3213821-111----1-1-1-1--- 1-51D11434721187644-49--4N444443DBCEHKnk343A59313112IIO533--44E1BFSDGC21111344--1-72-311--1--1--------------1--------------------------12223--1-4-11--------------------11------------6732411-51-3333334425333236333113511456211---11165----1---------------1-1-11----1-----1-----------------------------------------------------13--2-----------3--1111--1--11---22-12-143511-2------5111-----21F88--86645277777775768-123--6-4F61-855A65798797C431-36D223346511111111221--1-2-----------------------------1-8B--4dWJMBFEKGB7CCC8GGNLDDCC6BL8UPaZM11BB673976J6C5KG23212-121111111----425-11--11112-----264364611-----------1-11--1-1-------------11--2-123-5-----1---11----11--------1-1------43542429667977767-6786868676687887888787441327376757777767666854455543-211221122222--------------1-671112-31-1-1211176846383647176562A79347953455222222222----311111121231122222111------1-11-----------------------1---------------1-----141111--- -----1----------1-------------------1-------11---1-111--11-------------1---111-1----1-------1----------1-2------112--1111-11--13-571111211111111111---2---1---3----1------1-----------------2---------- * a.4.5.33 Transcriptional regulator IclR, N-terminal domain
[ 528] 11-2121-1111111343111218111121-1347332311119B598453431322-2241--51-- 231--121---1-122133-33--6233333433243526111111--111-1111-1--1111111111111111111124311222434425111--26-74253-2-111111-1-1111-532357116233321-3341334213322133343323222244541432221422221211133411-111112111111121------11122111-1------1111111111--111111111-11--11-11--11111121----111111-111111-----------111111111111--11---11112345A5555555A5947555ABC676533325199842322452232331231622411111315444213332211111111112-651383521231211222443322364526133233-2211111111231-131211-11111---1-1111-11-1--11-11-231413233454444435545665544445469655672465337386455633634342223222222324346419967485456666367664658A56656486-21-21111211--------321-411232-6322-234444425654433647632--23534------21-12212221222322-2323322224222222222323221--3343333333233333222222221-111111111111---2111113444251-1-------------1-4233422446313333232273344332211111111142222111111122244333333332222-155212111--------21--------------------------32124323331321 -12----1712--1-12112111-1-11111-11-1-11--11-2--132411-21-1--11-1-1-1111-21-21-11----1--1211-212-5334-13-1--28-5AAB6754343454DA386W*83B6H4844A557555483721G65443-11633-64232-5125656U5644376BB1874333111 * g.41.5.1 Rubredoxin
[ 529] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2222222212222----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---11----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------E-----2334742644444444434444444444344333444445454444444333333323443335424433333344455475746774135ABC24-1nns*y*ZNLMJSXP*pLvR**v1tg*JPFIeOVgYEaKMDTKDpZbTYjTWTUgVHIUGNV9RYI1-----------2-5----1111- * a.4.5.14 Forkhead DNA-binding domain
[ 530] -------------------------------------------------------------------- 124-a--1------11111-1---2-11111----12121--12-111-1--12---1--66313-2CBF2----122--1-3-----CEOA-711---34-1-M13-8-----------------------1---11-----8-------------------------------------------11-----------------1--1------1-------------3P--------------------1----------11----------1------1111--22222222222-1-----1-1111-12---111----111111--1-223-11-KJ93-2---------1----------1-----6111-------3-----------------------1---------------------------------1---------------1-----------------------------------11-------111111-----11--------11--1----113--3--1-------1----------------------------11-----11-1-1--11-14-----------------------------------L2-1--1------1--------------------------11------------------------------------13----2--------------1---------111111111111---------------7----------------------------C-----------------------------------------22435324442222----331122--------1----------------------1-------12------561 4612869-913134345343333223322122222222222222223333224322322332423333122323323223322333333233531322224524543888*LOTaQUHEG9FNJbdIZJ**T9aQjFFFFJDMQLDJDBFWCGgLdJJN9BJzcjA7B97C8BSD17A7B34453858A37W498C567 * b.18.1.9 APC10-like
[ 531] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------111---------------------------1-----------------11-----1----1------------1------------------------1--------------------------------------------1------------------1-----1---------------------------------------------------------------------------------------------------------1--------------------------1---------------------------------------------------------------------------------------------------------------------- A947GEC-Q897CE989A889A98959AAABBAA9A9A9979A9AA9899A99989A999999AAABA6A98AA99A689AA999A8898B99AI9B99AA97BA92AFBNObKKUFHGEGFJIRSGSF**N2UOhDHHFNFITCCHFDEICBOGGBGJCDCED8BADAINAADB8ABC*AAA9BMKTRAJHAABBBDF * d.110.4.2 Clathrin coat assembly domain
[ 532] -------------------------------------------------------------------- -----22-224-2------------------------------------111-22--------3-----2-2---222----------------------------------------------------------------------------------------------------------------16C6969A68AC96666AMCKKMG8766861847NQSTOR8428887887888888863345H6--EK--8-7HI--CN-264333424669979878B99979B7A58666666666666658822-888B-5-BYCCCEAAEAA8-k--2222-2-2-9-3-----2--2---GFB--11-----------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------21-----------------------------------------6585-723116366652-1333466531161333333787AB222747657787874846663213333--611111111111---------------------411-1111-111---------------------------------------132----------------------------1-----------------------------------3-------------------- ----------1-121--------------------11---------1------4---------------------1---1-11-------1-------------------21-22119I993kHpWAvL**v3YSfEHA9d9F*V9PKA8NA22---2111---1-----2--1------------111-3-------- * a.142.1.1 PTS-regulatory domain, PRD
[ 533] ------112112121--------1111211214121111111111131112121111--1------11 3333433233332354555-555566666665555576B93444325221122222221144524333444111111112222222321111121111-212245212211111111111111223221122-22444331113244422232233222223322255331121321111122222323124244444434253444323333335233323222223222222222222222222222222222322322222222222222222222222222222222232222222222222222222222333222212223222222222222221322222122114132332222223321-1121-111211111222223121112122222222222-11111111222132252342323211111211111112111111111-11-13111111111111111111-111-1111111111122111111-1111-111111131111111221111112111221111131112213111221111111221411-21132232242212212221211332324221111111111112112111112111333322223222223222334222222342321-11111------42232323343333333-333333333333333333333333223333333333333333333333333212222222222221111122111222124122222221111-122232323222221222224223243332223122122222244432222222333111111111111111-323332111111111111--1--2---1-21-----11-1----22222221321211 22221-1-2-3342566878787656744353445634442345449457586935655653244453255663455255566565423486635465345158C913C42555355453143455453BU613381322325454344234374553714242421833255424763K34376C7AA3A43445531 * c.143.1.1 CofD-like
[ 534] ----11--2222231--1-----11-----2------------1111-------1------12-1--- 12215122111-1133323-23--3321222233333464143563221111665211--42414468452211122222323-----2222-112----2-1-333-3---------------111111-112123322111323232111--11------11-22232-1-----1----34311111-132222222222222223333432222222233333333212222222222222222222242335412212432234333221343333332311111111111111222222222221222233122232221111111111112122111121123311--22----12--111-1-13122226------1-11---1--------------1-22122121243-1112121221121213---211111-111111111-2212322------------------------------32222-11-1------2----------------------1---1211-11-12--1----1---------11-11111-1-----1-----212111112542545--------------------------3--1--212-111-1222222-2221111-12----2---------21---121111111111-111111111111211111112132--1111111-1111-1-111-111111--111211111111---1-----433312111-------------1-11111-1---2322221112212111111--------------------2-111111111111--------111112----------2--------------------------12--111111211 3123456-94511-62122213212141122322222222222222332132421132311123322312422123333222223211122213132322222644-B76KKPDILPHEGBEHGdUDYHw*W5UHhFHH9IFEMCAGFDCJEBcEEEHH9JL7DC7AP8AVABB72465M45446DDEM3H95466873 * e.52.1.2 Diacylglycerol kinase-like
[ 535] 111---1-11111111-------14--2-311------------1111--312-1--111--11---- 2542E-231111--8D7CB-DC44EDBCABA9F68668II274C95113421535311--8A4-987E992-------1-121--21------------2613261524--------------12---32-11--44455---4185624421-11--211-22116443-1----------4211----11-777776871656546141132874111223311121116-11121-1--111--1--1--111111-21311--11---312121-------1-11--1-12-11---------------111111111--22622211112213211-11-2221-1-11-221----21---1-1--5-182231--1-32FAB33357168--1----1--2-76367145189-5AB43758695A6334-13312-4233333333331563425----------1--------------------55753211138EEDA831221339433331-B986597-15432331162-272224-----1--------21214213--11--21----544222612113286-111111-----11-111111121-1111111-1112312--3--312-1----11-211--2111-1----12--111-------1---------------------211121221----------------21-----1-----------------1-----2331-3843---211---1-----6775746-436132236975364665454-11-111-1-211-11111-212256545442221-1-1-1-43--56---------------1-2----------1-1-----1-1221-111-2-1 ----223-631156477796666667722233353337A7769333A76EBAAJ69775533212-2112-12-2--1---44322--1BB87771---313523314IAA1572733111-31212728M3-238113242523153121214423-712--431--2--24293664C253A3IEMR6GB65CAEA4 * c.69.1.12 Haloperoxidase
[ 536] 11----1-----------------1--2--1-------------------11-1----------1--- 4MU-6---------------------------------2------3--1-1-952-----541-4--JB82-------------------13-1--1--13-4787N-4-----------------A21----4-22222---9-622-1131122----1--7-Q319J-----------------------11111--1-1-1---2222-2-1--------------25--------------------------------------------------------1--111-1-1------------------------1--4-----------21111---112--1------221--------------L1------------2----------------------2--2-----------------2---111------121--------------1--------------------------1--------1------------1111---1262121---1-1-----------2----2---2--------------1---68251--111-1111111-4141-1--28M15--------------------------------72-3----1214-1--311-11133---5---------------------------------------------------23--1-------------------------22222222222--11---------2-5----------------------------7----1-1-------1-1-------------------1--2-1---1-----------3-11--67-------------------------------------1-121---1-X-- --1195*-----221--2-622-2-21-------2-----------1-14478433-3----1----11-------1--11--------111-1111111111332-7A2aYWYdWbMOLPNPQxhQhP**X-iSxHMPLaNPURFRMNGdNExMLGPWIQKEEA86E69M33A4-122C1-12121-2-11231---8 * b.69.8.1 Integrin alpha N-terminal domain
[ 537] ----------------------------1----------------1---------------------- ---------------------4----------4-------------------------------1--------------------------------------22---------------------3--------122-----5-222-117-------6---5--234T-----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------5----111---------------1-------------5---1-------1--------------------------------------1-------1-------4-55-----------------1--------------------------------------------------------------------------1-1---12-----------------------1-2-----------1-------2-4--------3--------------------1----1111----1----1----1-----53--1--3--1------------------------------------------------------------------------------------------------1--------------------------------------7------1-----11---------------------------------------------1-----11-------------------------------------------------- --1---C-----11---------------------------------------------------------------------------------------------R2-ycpvq*fQQOLYaU*yJ*F**x9*b*SKKRYUTWMORKKMaUG*TidaqGf*COdC4DA6Q7H*6-2----------------123-21 * b.1.27.1 CalX-beta domain
[ 538] ---11-----------1-----------111-111---1-1---2-1-4--------------1---- HLg----------------------------------1-----------1--2-1--1--1-1-6--1211-------2312------2254-321---1811193632----------------11---11-3--1128---7-----1--2----1-----------1-----------1422-1------------------------------------11111118-1114341--111111-2111-----------------1-----1-----11111----------------------1---6-----------------------1-----1------11----332--1---------1-7-31--1---------------------------------------------1------------21---1--------------------1------------------------------1-22-2----111-111222222-1222213--112------1---22-1--11-1----------------1-1-13-3-------------1-113--11-2DC-----------------------------------11--11-----1-1------4------2-------------------------------------------------11----------------------1-------11111-11111-------------1-1--------------------------1-1---------11---1-----------------------2111111-12311------------11------------------------------------------1------3 1---A92-1-1------11-11-1-11-------------------------11-------------------------1---------------1111-----------5FaBOqKNPACJQImgMxM**m-*igIDJQgNQse9IbGNfPAVQYLLh24211212321D1-11------11-----2153-41---1 * b.3.5.1 Cna protein B-type domain
[ 539] ------21222222221211111-------------------1--11--1111--------222--11 3421432222221131111-12112211111222223233-22211142221343233113352332B6611111111----------11-1-1--1--1942262444------------------1-1----112211-----111-441-1111111111112111111-1111111-1-11---1-----------------------------------------2--------------------11111111111111111111111111111111111111111111111111111111111111--111---1-11-1------------11----1-------1---------------1--1-142211111111-----------11111111111-11111111211-1111111111111112-1112121111--------11111-2-------------------------------122121111122222222222222122222222111111122211111111121111111-1111111112111111-1-1----------111--1-1-331365-2--------------------1----11111212333313444443344443445434--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--141111122221111111111111111111122222311111111111111111111111111111-111-1111111111111113444433311111-2-221111-------------------------------------1-----------5 1111673-744-66465444644444544445433325553544544445466644454444575554456575755256544444333593536443335435664646QHHGLJICBCBABAEDBIAY*J1JFRAC9BDBDJEBDCC9HCBKAFCBBBOXMQCNKfMXnIOGM3454P53264858C45C348DB83 * b.98.1.1 Leukotriene A4 hydrolase N-terminal domain
[ 540] 111---31444445312-1-21121----211-1----11-12-1111---21-23354321231--- 1432421333332-51222-251192222223477757EC471311112112327226--64B31196713133311142C421211111313511---12-1112221-1----1--1-----54556557416---12333--433223322331111121311212334322324222234211--111411111211111121--23333111111132344444447111111111111111222111-11331-2-1--1111111-11222------1-221--1-----1-----------------111----1368888889B98A832AA13345231115244C875A3161944514113222113--1--253341215311633333344335122422532353-44434353337622222232212232244444444333154312212211122--11--2111111112211225912233226565774222233743444137662422-1215424214213241242-1333--112111116111BD54525249764-344262563344434361--1-21111-------1-1332-211123311412221222221322222142376---2342-------1213311112112211-11113121221221111121112----1-1112111111111132222221--2--11--11-11--1-11111111-31-22---1-1------1--11--1-22111155241534133222424---------2345444444545331122212112----225222--111---11-1213---------1-1-------------113132-22-23-- 2211433-723142657339234B38622131111142313222224344398A753451232122221-225222113242211142245474354333333522-1F242-2121331243365493Dl8-74312117215213112323511-22332351325116423-2641Y1312475685983431346 * c.4.1.1 N-terminal domain of adrenodoxin reductase-like
[ 541] -------------12---------41111-31211--1----21221211111-1------1------ 1241123322332321133-3722213333316123322211111322222231121122122222111213111222324122243334321112111242441331111111111111111221121211221333352223143121141133112111352364321112222122222422232111333333343333433341443333411222424334332131111112111111122222314354412112211545122221113222122-22111111111113333333333333121111222333524333333333323553333322422222143422332134233143413122411111226386553343322232333333-34535344484143335557725634222113131121211111111322122241111111111111111111111111111112122211111734544333334412444425346333514441231232542216222223442211211241322223223123131213333111111223333332121111111234222222234123113441232121423222232222322222211-1211111111124133332222222123-2322222222222222223334334422322222222222222233222231133333333333311111111122233112311121211111112111111111212322231111221122321211112111333333333334322211111111111111113222211111111113231-11-------11-----11-----12321121111443 32-1653-9331333222123232112223323333433333322221322242131112112-21121-11213121222111-122124222211222221256-19345437242233123673D4IY6-99F322262342223533328264131--43212623A23345858m85498KFKH2BF4743244 * b.35.1.1 GroES
[ 542] 11---42-111111111-11212212-311-11-----11---------11--11-11321--2---- 112191-1111---74411-17--4611212277877396111311--2512263-11--43416398561---------11-1111122132211212131221122311111111111111111221111241111111--213113131111111111111114223111111111111221111111222222221212122212211212211112221111112133111111111111111111121111112211111111121-111221111-111112112322121222212221222221112221111221-2323323432311332222322312212163232123151241122211333311121333342212221111211112112-433441353632433212422144311212132222112222222222111133111111111222232111213213211111112522222215334434233144333333136442344113313233232314511211212211111111212211B532212112551111222111112-14216111112332311111111111112122233122111111111111111111311211111121211111141313113333333332-33332333233333333321111112232313333332232132223334222111111111111211111111111111521111111111111121112211112112343433113223223433111111111332222222222221121312111111111211111221111121121111111-211112111112111111113112122112212 32236341A3333554645457685734434443454454664444464577696563255464634345354443323335577454427665343343533874144756655C4433434576254Hj6-8585245543632454374298733434543343444A37576454k55646DBAN6C46444354 * c.3.1.3 GDI-like N domain
[ 543] 22222113322233323112211123321232--2----1---2-11541131-1122122--11-23 -13-734122232431211-13111211111132325256123342212311424222114323755354423332222111521223112111223---21--12-3-3222222222222222222221221243345324612434342432232232223234332222222232222522222111212222212222131217433241315245331444444244333333333333333445441314413222551144223441312444745532233333333333344443433333443411133331522422222233231-222221222443-11454312122223222182411322222222149473426666522212122223-2322233394424552334655345C--14576366333111111112632124611211111111211111111111111111-3322-253243334332333333522222222444544--332353342314441173-1222111111111364432333532213222-223221312442344231113133232111111111132242113331431-1322343332333333223453--226541-----72442432334244422-3222434243354222222454664333333333333333333432433333-433333323333--31222211-1-13532212222222222242121221111143666656684565634441111111113533633333555442--1-1--------114211-------1--1-2211112-------1-------------21211141111-11 21--342-113-2113-21-1--13-1--1--1----1211128-A23---23223-31112-2-11----211---1---111--2-1--3-2241-11163135--33623212432--1215313-DW4-53723314134211212611332343241A533231211332-24-2--1334216221211943- * c.92.2.2 TroA-like
[ 544] --------1111111-----------------11-12-11111------1323-1-1-211------- 2-6-332233222243322-23--3222222324442233323222322222-22222--22214-2323222223332224------55442322--222--22------------------222-2-1-2222----------252222222222---2--222222-----1-------534--224-44444444444444444224444444444-4446666673323332332333333342222486266224646645446444424442222222222222222222223333323323222422222222238668666666646428222666243226222-5522-2682286626222-42--4-----245466222C22422222222222-6D456424232-2---2224322242--24-233334-222222222222--2-8-------------222-32--2--2----------2222122222222-2254322222-22862442--22-4--2226-3212-222--424444444222426-6--22452-655426882846848898--426222222222222-2-22-42---22-45A22-2-2-422222334222222223422-2222-22222262222424445444644-44444464544644444446663322266666666666767662444444432622222222222--22-----22222-21222222222222222322222-22226-2232----2----42--222222222-44444444445444-----------------2------2222222222222222-4222222222222223222668667677522-- ----11--21-1223-22223342323222222322323323412123323322-3222223----11---1-----------1----1352234323332-211--1626133352112112254155BR71737211-31141-1-1-2212-11152143312121144232-49-----34622522B5-44443 * c.55.1.2 Acetokinase-like
[ 545] 111-221111111111------------1---1-111------1---412666---------1---11 -29-----------2------1--22-----21121--1--1-2-------------1---------121-----------1-1-5-13312----3------151-11--1111--------61-1-2-1-35-25454---9-7-7112921----1---1-33-27H-3-2-115-211-11-----11---1-1-111-11--1-----1--1-11-11-------11---------------------------1--------------------------------------------------------------1--21-----11-1-----1---2-2-12-1--11-1---------1-3121----1-1---1-121-------1--------------2--21--1-----1-----2---1------1111--------------1-3-2----------1111--1222-1111-1-1---11-1-----------1111--35------211--------11----1------1--11---1--------1--13927-13--1----1331--1514-1-11C22------1-------2--1-----1-11--1--1----2-----11--------------213---------------1--21----1---1------------1-----------1--1----11--1-1---------------------------11111---------312-----------1-------1--------2-----1---1---1111-111-------------11----------1111-115-11122--------411-------------------------21-1--1-1-122- 3413CE6-A21173B5453D673686545643344585243555344436838757656444232343315433244244432214342334483X66543B3AD7-457*QQMPMKICGGGRKbX9U9**O4ROeGEGDXFOSGEKHDARFDXFQIIKCTFBHD94IEEG6BHZ4141O43274D45F5A76754659 * a.7.14.1 MIT domain
[ 546] ----------21-----------11---------------------1--12-1----1---------- -13-1------11--------1--11-----11--------------11----1-1-1--------1--1--111-------1-----11----------32-2--1---------11------1---1-22-----------1-23322213311-----12111---1------------1----------------1---------1----------------------------------------------11------------1---------------------------------------------------1---11111-11-------1122-11-------111-------------2--22--------2--12-----1--1111111--1--11-11-1---1-1221321-111--2--1------1--1---------------1----------111----2-1----------1-----11--------11111---2111111-11----11--22-1--1--111--12--121---------112-23-2--1----11212-121-11252335711-121---------1-121-1-3--111-------422-1---------------------1112--------------------------------------------------------------------------------------------1-----------2-1----------------------11---112112--1---1-122---------------------1---21-1--1111111---2--2211122-1---11---------------------------1-1----11--1- 5447GG9-I56286GBFFDBFECCBECAAACACCBCABAC8BCBAA9A998AA98899AECFBBB88B7C7D8AB7A4AA9BBA67A899CAFA9B655778ADCE1BCEVJLEHGD977BBGAHE8G8J*C4DBI9AB6D8DGC6BB8AFB6IAE9ESBNJ8GDA8Q98H8BIF4DC9*9E77CIKMOAOO7AACCF9 * a.118.8.7 HAT/Suf repeat
[ 547] 111-111111111111--------62224-22--------1---2--1------11111211111--- 2322221111122222222-2422422222224333226623242242122178542222225238A3222-------1--1B3--511211-112----211131111--------------11111111111122222---2423222222222222222222222222222222222222212211211111111111111111111111111111111111111111-11111111111111111111--------------------------111-111--------------------------------------11--1111111-1--111-1111---11----33-1-11111112-1--2-3322222222262432222223233453453445-663685636O31E9A8A8BA9DDE882229D75556IFO333333334222723211111111111111111111111111111924621224424444445333344594444244653532112264222242223411224142222222222222221-2-1112111111-3221111-1222223-1-1-----------------------222212127223223233223222322233321-1222411111122222222332222222-321222222232222222222222223222222222222222222222222212222222222221112222223222222441111112111111112222224222425555555996855277722222222222222122222232234222222222222122-111112--------1-1---------1---------------11111111112211 33--341-93412233343344234362232233332222222222342246443353234322412313222541323223234322223333242443122354-393J775677555346466494L*5197F4562754562544564285555747A38674459437752334N4353372383443542336 * d.250.1.1 Aminomethyltransferase folate-binding domain
[ 548] ----1--1111111-1--------1--1--42-1----1-----1-----1-1--------------- ---11--1-----121111-1311311111122141-3131122-111---1221--1----1-2-113121111111------1-11----11---11-112111111--------------31-1--------1--1----1----3---1-----------3-2111---------------11--1------------------11---------1-----------11---1----1----11111-112-111-14122-----1-21-211-------1----------------------------------------11111111-11-1331-------1-12----------------1--------------23-11----2--12222222122-------3----------1----2-11-----1---------------------------------------------------------1--111-2112121122122322222-2122----1-221-11----11-------2---1111122---11-------1122---1------1-2--1--1---1----1111111-2112222---1123------1--12-----------1----1-1-------------------1-----------------------------------------------------------------11111111111---1-----2222113-----------------11--1----1--2222-2311-111--------------1----------1----------------111-2211------------22-1-----11-------21---1111---1--------1 331245M-SC735455483445735464444343344444424644455484563654355665565426455654445456666634549745356655446C8E18D7VXjXVMRJGHHHNLmoGZF**U7eMuEJHDWGHJHBKJHDPECXJJHIK6B9KOIF8S99T78G42423Y33255944A443557BBD9 * b.34.10.1 Cap-Gly domain
[ 549] -----------1---------------------------1-21-----------1-------1----1 1111111111111111111-1-11111111111222213111111111111111111111211141112111111--------211-12211-1112--21111111124111311233111111112111112--11-----1-11212221111111111121221121111--12-111-------11----------1-------1---1----------1-----11---1-----1----1---1---------1-1-------------11-------1------------------------------------21-22333434423-13---111111-111111121211--1111-2-1-222111--11121-1111111111111111111111--1----1-1121---------1--212-1--111111-11111111111111-1111122111121111111222112211121111--1111111111111222211112222212212111-1111121111111121111121221111111111111222321111211111232222223111111121--1----------------1----11211122112111111121211111211111--12112------11111111551111121-3111131111311-111111111112111111111112111111111111111111111111111--11-----111-2-11-1111111212-122111211111111111111131111111111-1111111111212111111111111121211111111111-11-----------1-------1------------1------11122-1-1--1112 22-1341-71--221C8EA65ADFKFE3372547635736644854G6A6GBFJFCGF84631-212-1442--2--1-222422211-LbB8F696362263241-481pJHAMBOC6CAFLELZ7YBh*G2HGYCHDELDJMD7GG89R39M8FFGH8BB6GB9B8ABF87D8-8737222356GG7B7541BFBF3 * c.68.1.22 Glycosylating toxin catalytic domain-like
[ 550] ------------------------1--1-1-1------------------------------------ --1----------------------1------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------1------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3334CBD-G7535564555555554555555565555555455555655555555555555545554535565456636655555566636455455555454CAB2FR8HkXXjbQIJMFJNLrpKgP**eBqQ*EKJIZJMYKAMIIGTHBjKNLKOBDMFAAG6HDBG89DB3667l77665IGGJ5NB989999D * g.45.1.1 Pyk2-associated protein beta ARF-GAP domain
[ 551] -------1--1----1----1-------------1---------------22--1--1-1-1-1---- 2223333333343323322-22333222222323335343244332232333333223224422222112211112112222222422222222--21122222222221111111111111124322222422332222222226323222223322222242223333222222222222-----22212222222222222222222222222222222323333332222222222222222222222122222222222222222222222222222333222222222222222222222222222222222222223222222222222223222222212--244222222232232--22222223222222222322232222222222222222322-2222222222222222222222222222232232322223333333322242242222222222222222222222222223322222222222222232223233224433332322432333334322222332422333222223222222223522222432353224222232332335532433242322222222222222222222223222222222224222222224222222222222212222222-22222222322332222122-3222222223322222222223222222222222222222222222222222222222222222222222222223333232322222222222222222222222223222222322222222222222222222222242222242422223333333422222222222222----------2----2-343323233323224333322222222223222 2212123-823-22333334333333433333333333223225334434322133353333332422132122233233333334333343334333323628BA125-74844323132343422528i614623312512552341233384422438532239424745534332M33412378A3664332223 * a.69.1.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
[ 552] ---1-11--1----------------------1-----------1--------5-----1------1- -13-2-1-----22----------2-------2---21---222-------1---21---22---23--1-----------1-----111---1------1-1-1-11-1111111---------------2------1----1-1-----1--------1---1--------1-----1--1-1-----2-------11---1-211--111---1-------------1-----------------------1----------------1-----------------------1-----------------------------------------------------------11---------------1-1-----1----1---------------------------111-1---2-----1---1------------------------1-----------1111-----------1------------2--------------111-111-1111-----11-1------------------11---1---------1-1----1--1---12-----------------1-11-------------111--11-1--1--1--------11------1--11------2---3-----------------1--111-----1-1-1111111111-1111---1----21212222221121121-1------------------------------1--------------------------------2----1-------------------------2-----211--------------------11--11--------------------1---------22-----1------------ -----15-D69186954737455445578565567757766668778D6466865454644448779438A85869656768AA77-21BFA489C7667AC6CBF-DB2uTkhfabHFE8GHFZhDZI**c3ZOfBHHDKBHMIBIICBKCAVLJDJRPZb2QF8CUABbLSRM1-11712-1--23272565LHGG- * c.43.1.3 Choline/Carnitine O-acyltransferase
[ 553] ---1--1-1111111-12------2--1-7-------------------------------1------ 785-J1122221-122222-2111232222221222322132-87761684-654--3--34429345A326333232-1-32-1---ABA5-7111--5D144462251-------------12222222222235521---2-2111211121111111111121111-111---1-21-121--5522-1---------------222211--111213322222331F1--------------1--111-1-11-211-----22-1--111121111-11--------12--------1--2-----144---444212226----------4-11-21-8121-213--11--1-21--223211-21-9773-----2223211112111111111-1111-221222211211511345344422118251121111211--------211-1112----------111111111112111----2151311111135545521333331133332332211121111231111111232112121221111111112112121221111-11111----2---12113114-11111----------------2---1111143-6714133222223211111123115--11111------23333223222322222-2232222222222223222233341112222222232222222222222221-233333313333--111111122221121411111112123132122222211111422222323222232545231122323121121111131122437868866633431-13221111222222222-4-------------------------32321563342722 ----11D----1-12FGGELHJCOJNL4444556665655655445GFDHMPeXNHIDBA9A64413--1--7281-12--23233--1AACG8C23683333536-3N-31-1-1---1---122-1------------1--2----1-------21133229L32-12-1111---11---41RGGTDH93-TQUU8 * c.1.8.7 NagZ-like
[ 554] ------------------------222---2-22---------2-32--2-----------222---- ---2--2244422242222-2-22222222222222222212-22222----324212112222-221-212444113332----11322-224-----2323145143--------------------2--2421443233524-222--22222---2---31----4----211---214-2212-2-11-----11-3-1-111111111---1--1-423332322211111111111111111113-222--22---22-----2-2222--111-----11-----------11-121-22221-1--------1122-222222222222-2221----1422-4-22221-2--2-33322-141-4553-------2241-232--22222222222-21311323-22335--33343312222-41--2-----2---------222-2-45--2222221----------------22-22125621111-2222221----11-3------22-3425--2221-13323121-2213---21-------33121--34341-213111113335475441242344444332222224434224224----233--11-1111-111111111111111111111-12-21-1-222-------1111111111-111111111111111111-111---------------------311111112-1--------------1222221111-1221222-222----222222222222-32------------------2444424443111122222-------111131111111-1-122----21122222---22122--2--25--2-1-211----2-222232123--2 532-524-M8B466535654754666633457744443232223225321243433A2544668A9BB5ABAB8B9A798A778976648I85B6CB8456459BD-4I6A4AE9898698A85BB48AF*6-75A9C38A9575777777677355835CD36551F4A387514978*647568FHj3OE384434E * b.4.1.1 HSP40/DnaJ peptide-binding domain
[ 555] --------------------1--1------1---1-----------1------------1-------- 316--------1---2-----2--11-----111112-6511-2-11--1--11---1--1-3122264---222---1---1-------1--211-----1111-111--------------1-----------11111---3-3---11-11-----1------------1---------1141-------11111--1-1----------------------------1-------------------------------11-----------12------------------------------------1------------------1--------111----------------1--------1-2-23111-1---2431231-2222-111-1111111-12122131311-1--133-434--1-3412---1--11122222222-113-12--------------------------------2712-11--54534332332333-455434663-212-21--1--1-21--2---1---12---------1---1-211-----11----212---2----1-12-2-1----------------------------1-211-1-11111---111-1--1--1---1-----------1---1-11--------1----1----1-------1-1-----1----------------------------1------------2-1-----1-1-----11-11---------11121-2-1-1-----111---1--21-1--------------1-11----1-22242331114434------11--1-------1----------------------------------------- 4812777-8141544LGRIBFGFOQPIEF6A77KGHAEEDCCC677KGAFOLeRGGGG8788A34343352333533133444474333PMEG5E996835C8679-8fIQFI67884376543C8253Op8195935446457436355633F443547AG4F91FDA65OM4H-996J235D7Nm**I*QA9OLJPM * c.69.1.5 Serine carboxypeptidase-like
[ 556] ------------------------322122213111-122--2121112312211-11111111--12 2221222333323223422-23222222222242323253223221131112211112123222232222212221112113212222-12--11111-11--111111122222221111111-1111111111211132222213211111111-----111111111---1-1---11111-121-1122111112212121222222222112222222322222222222222222222222222222221222221222222222211-22222211111221111111111132121311111222111111112122213333233232122222222222222121112322212322211-1252111111111111111111111111111111111111112121111111111111211111111111111121111111111111112111111111111111111111111111111111111111111111122211111122211122111112211111322122123111311111222222222111322122211222211122121322332222234431312222221111111111121341223111111131111111112111111111111-1121111111124321113344343533-53333243354433333333232123242222323323333221344321411333333333333111122222333331111111111111-12111111111111111111111111111111111111111111111111111111211111111111111111121111111111111121221111-11-1121-1---11-11111111111111121- 2212554-H982433436345444434554555657344544575549343323343543323332342543434542433433332235723527623538464C1463I8B7B855854497CB4A4Mq8194E6256E379556543E54C6B58g2A35969EE45456449434Z44363aBMK5F82156685 * g.54.1.1 DnaJ/Hsp40 cysteine-rich domain
[ 557] 11111222111111111222233-411533561121222224276233-357421211121---2--- 2241542322311121111-13111411121134444468123432-4-51-261322--221-52317332222143--211--1229A58-621----311125524133333312221111----3--251-699251222-535522422333--11112-73441--1-1---2-1-211--12-131444446552553765-32212457132-3212222231722222222222222211113326-2215121873311433--25252221---1--1111111---11----1---1---311-1-11121213733343233341433112122411125-23321111--1---1-135-3522133322144422213355522332331335-5445485549227AA3876B99663331234463875542222222222332412------------111211--1-11----11322123221244425332222223333332453531-212421423223225431122111314223422--27311342525821445541112--211111143313221111211124222122212223226613351251246877224645465543751-12222------33231415446576643-455564667645644444422333311353333333333333343523244-11111111111111-16111112223123131112141----1113333333112-1333443521212221312223333222-569765555479662-222231115444211-22--31--------111-------------------------21-21212111242 211-411-2111-1435435555334544233356434443544233333552589443523212-21111221-12111-1111111132-511-3231234--3-12-1-21--11-----1-1-11121--1--1---1-2--1-----------42---33-12--3-1A-21-1621216121F333314445- * b.81.1.3 Galactoside acetyltransferase-like
[ 558] ---1-------------------11--31121--11-1-11----2------1--------------- 222-2144--231325534-332241333332-1113657-5261111221333323522--3-34212421222333----1-----11---------15245413221111111113111112213322221211121---4-2122111112211111111113232111211111111322--11--2122222335-3323331111112221--322222222312111111111111111111122-1-22----1----24-111--2112-1-----11------------------------122------11--11--------1----------1---2--1---------------1-12-31---1111154324-1----1-11311131326-22722434142-75483564864845-13456313423211111111211212-211111-----11111111111111111111-12--32214111111222221136432322114632213---42211134243222-11111-------111-3231--2------11---------1-23-2381--1---1-1--3--------------112--123112132221222143311312111--11212------131112-1222111111-111211111111111111111121-------------------21121111--1--------------2111111111-2415---3-------1--1-----121111-232214332111123441111111112---1-1--1-----33122223332222--1-3311111111--1---1--1----------------------12-1-1-----2-1 3-55646-7233566BBF9ABCFFDCE878A68AB7A978678535BCB9EDGA89F8AA5B365353336522454363555735456665B3756654768465-4dCD9866863234335A53E5Rn6-D88242242383335543333666265813A7447554586616CCj8A9479FFQCNS69C8DBL * c.69.1.14 Carboxylesterase/thioesterase 1
[ 559] -------1--------1-------------1-------------------11-----11--------- 1-6---------------------1------1-111---------1-------1---1----1-112431------------1------1---111---111362-153------------------------1-12212---3-21111111111-------11---13------------1-------11111111-----------22221---11122--------32-----------------------------------------------------1--------------------------111---1111-----1111111-1-1-22-112-1---1--------1--3---------5--1------------1--------11111111112---------122-------1--111----2-11---------------------2-------------------------------112-1----12223222211111151111-23211211--221-321111132-1------212211111---23-121---------------1---------32-------------------------11------1-122232222212233315234142----1--------------1-----------------1----1------------1------------------1---------1--------------1--1-------1411-----1-----------------211-2112-32222221-233---------12112-----23211221-1-----------1-111111--------1---------------------------------2------1 -112218-3216446158911112112221111333333333311133446857DDA4222211111111111211111111111122112151211111112----6A5uaSPSTUOJLMLLObWKRG**T1XLmINLOWKMPLLNLKMNIKYMOLIOIPNHZDgekMRiHITA1873L2213333247422277795 * c.56.5.1 Pancreatic carboxypeptidases
[ 560] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------21-----1----21------------------------------11---3-------------------------1---------------------1111111-2----12-1--11-2----1------11--------------------------------------------------------------------------------------------------1---------------------1-----------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--2-1--1-----1-------------------------------------1-----------------1--3--------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------- --11--2-1-------1----2------------------------------12-1-1-111------------------------------1---------------X-*erd**gQJMJMRR*iRgL**g1*ZpKPSKeJSaNJRKNGWKFmNpRMagzY2i*C4634347**-----------------------1 * b.29.1.25 MAM domain
[ 561] 1---1--1------1---------1--11132----1-------111-11--112111221---11-- --1-1---------------------------------11-------1--1---1-------1--1-111-------------1------1--1-----3-1131-2-1-----------------------------11---3-1-----1--------1--------1---------------1--1---1------------1----111-----1----1------------------------------1-----1---1-----------1-----------------1---------------------------------------------------1----1-----------1--------1-1-11-------1--1---1------------------1-1-------1--------------------------------------------------------11------------------------1------------1------------------------------1---------------------2--------1-----------1--22121111-----------------------1---211-1--11--1-1----1-11-1-15-2----1-------------------------------------------------------------------------------------------------------11-14----------------------------21121-11-1-1---111--------------------1-1---11111--------------1--------------------------------------------------21 --11--4-------1121122212223---211---11111112111-132252422-12111-----------------------1121--23114-31-11123156-VWeRgSqRPSRScV*zQ*R**k5ua*NTOSyNQ*hKRTSLhOLuMSRSS8EVa9ZE5D77W89MB17E1A-239---1-2-16B31A62 * d.92.1.9 Reprolysin-like
[ 562] 1111111-111111--22112111111--11-111111111111111111111111111111111--- 34824---------24311-121143111112243543711412222-111-224---11-153413443-1111-111-1-2222221133-1-----12-222-2-2---------------111121112112223311122-12-222--1111112221-12113-2-----211--1213322-322224242332353335334423333122131122222216--------------------2-1-12-1---33114511112----2311111-11322333222221111111111111111---111151-14111111111123--113-412--111111211112122111521-1133112-----3188A-112133-22222221224-21522425-75-7223447544774224145231345122222222264313122--------11--2-111222211211-11-1251-22224567875344435588454434B385475-3553212--3-6467112-224---------11-131-112-111211111-1111222111111232111111-1---1111111111211-2223132122-33-1---1-1-1111----1-2----1-2------63441356446666566-46465666564775555559A74521-6466666667656565545444554-355555546666-------------2222622221311312333211-11-3---4244444665137411464-11111111-1--1111111111211313111121111--11331111--------2--------1--11--111--1111---1121122222-61- ----321-36-11216796633485544565453333333333333543449D612513222232323121141222111233343225--372221121422224-193C7786895341454FF5C5SlE1E8C45439456545645654B5454624135343739669541-21-1111431157551321216 * c.74.1.1 AraD-like aldolase/epimerase
[ 563] 11--------------1-1------------------------1-----1----1------11----- ---------------------------------1-1----1---------------------11---1121-----------1----------------------------------------1-----11-1--1--1----1---1------11--------1-2122---------------1---------------------------------------111------------------------1----------------------------------------------------------------------1---------------11------1-----15-1------12---1---1-1---------1-121-----13-------------1-1--1-1---------1-----1--------------1------------11--1--------------------------------------1111111-2222--2-222211211-----1---1-1111--1---------------------1-1----2--1-3-12------211------1-----------------------------------1------------------1----1------1-------1----1-------------1-------------------11------------------1-------------------------------1121-------------------1-------2---111-1--1-----------------------111111------------1--------22----------------1----------1---------------------------2 5523366-K994A8812223432224322352333232322222323212122112432112211211312311111211111111--121224222112151A79234DTXlYVWYMINJMPJ*uJxK***3*Y*JMNLcKMdPHMMGHPIHjMSRKPBFHJCGCFUB8R5MGC-WF5722222-541221EFCBBEA * a.211.1.2 PDEase
[ 564] 33414311111111113222232232221132112222112222222322222133343342222-11 421-2132222111-------1---2------31112212-1--2-2--11-1341-3--11432594213-1111111-1--21111-1---1-----12---4-517---------------1111111111133222111221211112--1111111111112111-1-----1----11-1122-312333333342433333333323343111-2121111--74---------------1----1----1--2-144--54-3----111222-1-1--1111111111112222222222222---11-1--1111-1222222212-11--23213211-4-22111251121211115321113---------22312---1332211111112115-11211113172-43333614544521---321322522-2222222233321115--1----------------------------1-1-1--1-1------111-12431111-1--3-112--121-1-1----2-1--11111311-11111---112-111-131112111111111112111111111----1------1--------1--1-23424121---111-111111122111-1121---1111------63573425447567655-455545654648655565466533-137778777786686786544355542-522242123333-------------112222222151----3231----------3144444634333334544----------3335111112222322222221111111--13111111--------1-1--------------111-1------153222443311-- 3345645-C45345544648787566566556554585656775454557666A65764564455665455654585355535546446454463554443B3765-566H76E7665543644873A5DYA-889445454474556335228568569F947464986G47744544Y42334659E4A45748564 * c.124.1.5 IF2B-like
[ 565] -------------------------------------------------------------------- -468722322222256655-5E44565555549689547713341-21---11121-1--3233336C97111111332132-112233322-3-----1823-73324--------------1221335222-522222---122233221--11343755-2213343-2-----2-----------13123343434434444442211234442221---------32--------------------14222232321442222223--1---111-1-1-------------------------------------24157443444454523332221-3312123121145324-21---1-22121411422222ADKGECABDEFED8899789898C-JNIKPGHHEI12CDDAIGHGGHGEAB-21D3A8888665111111112--11111-----11-----------------------55511-----1111112111111111111-11111111----12111123112-2141222262222222342232F2211121121111-66626372544-42D773111-1111111111111111112D556631632---334444334555334443441-33432------65444536666666666-66666666666676666676664432376667676677575684656666511323233333333-112AAAA9BBCC91531111111-1111111122222222445255553444426235222---------2111533333443333323233222------31--------------------------------------------111111114191 ----1------1--------1----------------------------------------------------------------------------1-----------1-----------------1-----------------------------1-----1---1-----------------2---------1--- * b.160.1.1 L,D-transpeptidase catalytic domain-like
[ 566] 11212-11111111111222222297765596112332223221221255777122153441221-11 333-422222221222222-22--32222222222222123222222212212222221133232223323111111133321223333333-3332113223443313-------1111111332312233233344331123334333333333333333332333332331222321223323333124444444344444444444334344445542322222224333333333333333323322222222222322222222223312222222222222222221222222212222222222222222222244445444444444424555555432134342233364333332344322222212223212333332233333333333323333-2232232234212332332333222233123232332331111111113322323--1--111--1111111111111111111122222333333333333333333333333333333333333333333323333333333333312111113233333333333223333224454544442222313411111111111-1-------1-112334443333222233333222333323223221-2232311111133333223333333333-3333333333333333333333332233333333333333333133233332-211111111111---3111113333323223333323321333333332333323333333233332222333332222322232222333332223333333333332222124222--23--------213------11--1-----1-1--1---33322323333233 11----1---1-112112111111111111111111-111-1111111-1----1-1-1111122111-11121111111-1111211112111111-1--1111--14-3522221121221131152AN3-6262222412122212212252222211413211122-12214313P53343433313233-1-12 * b.40.4.12 TRAM domain
[ 567] 22----2-111111211-21----11111111--1-------------------13-1---------- ------------------------------------------------------------------------------------------------------------1----------------------------------1-1111121221111111111132112111111111111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1-222222222222332222222222222222222-2222222232222222211-2222332222322222222222222221222122222222222221122222222222222222122222222222222222222222222122222222222222222222222222222222222222222222222222-------------------1-------12---------------------------222222222222222222222222222222221-1221222222222222222222222221-222222222222222222222222222222222222212222222222212212222222222221122212112222222222222222122222222222222222222222222222222122222222222222222222222222222223222222222221-222222-------------------------------------------------- 2211443-622-2343353322222333332223342544445122443445543385433433333321334333424433344543329533453434233365-2C4k9GIDDAJDILNFFmVEWL**R8URiJJHFEHNKFCGNFBVCCk86ABL4-17B98E8EP85573455393224354682744334234 * d.52.6.1 BolA-like
[ 568] 22212722555556655154324512241111322241--11-3334232255532221412333111 46712111111-1-1-122-22--1122222-122211221451111-11-1121-11--1331312143-222222243562312-16567-533---22121213-2--------------173352414354111343221-4378336233332421244465587-21----22-1-1-1--2141233333344343535351355223333223134222222344444444444444443442221-12211111331122221-11222333333434433333333333333333333333333333333333546C4346556978656655647431426552756181342411-3225-262333-----234343235664521222222222-66467368352143333323442343-12-2413111123333333312222515------------1111111111111-----342422111322222323333223533333322322321112313322323511333252432-------1126451I6511342512332474679644455469252111------221-------22-2211445312322144544455532334355364--113231-----43343434445444444-4444445444454444444444234534344444444444444344344342-333333333322--112122211112222333322223323211223333332331334245435344444233---------14455444442344431434334441111114-111111--------3-2------------------1------54343645562633 1--------------111-1112111-11-1--1111222122-1---111111111-1111------------------------------1---------------2---1----1--------1---1---------------------------1--1-21-----1----1244I3332--14-111-3---11 * d.350.1.1 YcgL-like
[ 569] 1111111111111111211111112332423211111111111222222232211111111---1111 1111-----------------1---1------1111------111-------------1-11---1---1-----------131-12-111112111111111111211111111111111111111112112121111111112112111111111-----12111112------------111111111112211211111111111111111111111111111111111111111-11-1111111112111111111111111111111-1111111111111111111-11111111111211111111111111111111111111111111111111111111111211111111111112111111211123322212232212333122222222222-332332333311122223322232222233212122221222222221322121111121111111111111121122212112-111112222122224311111111122221132122121134212223111124122222232222222222211221111111212111111111111122223111---1---------------------223333333333333333334444333333332-2333321-22233333333333333333-332333333333323333333333333333333333333333333333333313333333333331153333332222334333333333333233332222222221333333333433333333311212112123333333333333311111111111111--1122222211111111-11-------------------------11111121111111 4413556-B45333535444444143553342444234342445544534446434444346433544435433455355434333333374564633444533433565BA8889A46555669H6C2h*9-J8H7753B569656655758D6A8767DH399C2334CA4866344Y4653684554669667445 * d.14.1.3 DNA gyrase/MutL, second domain
[ 570] -------12--1-1-2-11----25--21311------1-------1-112------1-11121---1 242-F2234441111-1----5--16------233313132-11733-13327242-4--21456697883111122321323311111-35-1-----12--1416-B----------------211-1111-134411-1133--1-11---11-------4----1-------------1221122-21554545545254455566552645413235237666668A2333233233333333432442-147--32255--76141---342345333344333333333333434444444444453311-333463488554657555435--2585221223132322333214283358422-212112------12122121211222222222225-11111-21-71-A554245666575--1-3244134341--------41-2-1-4-------------------------------1---232--4557565444477584444146551131--------2-4--1-2-------321111111----12-24422442332222322222331222221342111111111--1-------111----5482-1121332156312244411341121-------------8766883AA9GADFDBB-ABABCDDBECAEB9AABA9DDF45556GAFEFEEFDCEEFFEFBA99BBAA2-857477647877-------------1--25666857445546876--1-------2145543342233333223----------2337444443336944--------------14--------------1----------2-1------15-------3---14111-11- -1-------1---2-------1--------1111111------------------1---111-1-1----11--------------1-1----1--1-------1-------------1-1---33-1-131-11--1-111-4111--11--11---2----1-1-------------3----------1---31-1- * a.4.5.35 C-terminal fragment of elongation factor SelB
[ 571] --1---------------2--------1-1-2--------121----2--23---1----------1- --6-634421224346532-2122523333332122246612233--12E74444-24--4451A1239A3-----------1-----3355-4321--221-191122--------------2---211111-1--------52M4A8238-----1-1----331-4G111-2--61---3-1----2--1-----11---11-31--1111-----112---11--1--178545757766777232313-------------------1-2-11----------22122113232-----------------------1---211111-1--21--------12------1--12111--1-----111271334-21111456C332273-A-------1----63944B38-41-1--5655578-311313461384562411111111-1111815---------------------1--------22-21-----2-----5122122-12122111311242--22155A652312-1-3423124---------34-33H221--14242223-2231321-13453IQ12-1-1--11111---------1--212212-4122243-44444442323332423441-1212211-11133332333333333333-333333333333333333333333211332333333333333333333233214333354343331123111111---1161-111-1--111-1--1---1-----113336323372-3242215----------13224333321111454-6-13336534--21332222---2-2222-11111-----1-2-212---13-111----1-1---1113 ----121-621--142-1-11113-211211234553111111332-12434521223111211-1---1-11-1----------111--2--211---1---232-1gAX7A97fB8796759B87F7M*C1E7J8A687A689498AA7678C85462241287F8B9621911CC22-11996667-2834BEBF6 * b.47.1.1 Prokaryotic proteases
[ 572] --111111112111111--11-1--111-2--5832423112332-11136543--11131---1-23 1342311211111111333-32221233333121311132222332221111211111116431312113123441221241113211444324222--23333434232222222222222213343533333433364---3178687764311221222443A8A752332322232322221133332333333444343345312333534422321112112116322232322222222222222111311313111111111122112224441111211111311111311111111111111211133111131355444344334355332332338112153343223231211112222221222322211212122222211311111111111-434443432512433558455644212133231111443222222222222232411--------223422333332332111121111112221222323222222222232222322322211322411221232213121423211112212523424366373554573332423232354333324562111111111135223332343121223433332342433222433322453424431-2541411-11123121323333333333-33334433333332232232223222222222222222222222333333311322222222222112222222142132732332332232132221224323232214222232422222332222222222221112322222333342212122211111122234322221111111111--------------------------12111121114333 1111124-4111333-131-112-22-11111111112332211121211141211112---31212311111111111111122222225314311-12--1331-17341322112122-2143222363-3232113222123212231-2123423652242-234112334445b33214A75C1A65516134 * c.87.1.2 Peptidoglycan biosynthesis glycosyltransferase MurG
[ 573] 111111---------12-1111232---111-111------------------111222231--1111 1221211311111111111-11111111111111112622511211121225252111--12215122221111122222121-11-11132-122---2322123231-------1------21--2113212111112245117323111111133232212-1111-322222223222212--1122222222232222223323223222221111411111111132333333353333521112112-221211111111131211122122-11241122-----1--111543342333132223333243312223333333333332144365512312246233253322221---111-1-12221-3215323323222222422222222225-55354C33443133363333345324222212131114144444444343244241111111111----11-------------25622133123111211211112222121211141121112331129217242211122217244543323131311135213263745772313324215113132143-1-1-4-221-1-------11121313331315122315BG734353351624223--21334------2611272377438383618337266434895343346653222273313132251445335443322327-422232222424--31222216676223B732343234344437363574612-11133575957277992A9A111111111244233535542244112332222253231182111112----------2-1-------1-1-111----11---11113122111311 2--2221-311-32222113121112122222211113333331114122323211111121311212212211111-111111112221522112111221132111423342231233233483152AH5-45731443243234343423425445-2114121321533311121K-1223337915522242-1 * b.87.1.1 LexA-related
[ 574] ---1---11---------------1--1---1------------------14---------------- --2-7---111----11--------------F---------C69----------------31---215874-----1----1------12-1----4------------12222222111111-31---1--8114111----6-4-2-333----1-------151319---------------------------------------111------------11111221----------------11------11-1---------------------------------------------------------------1--1---------------------------------1---1---1------1----------111111-1---------------------------------------1-----1-------2-------------3---------------------------1-1----2-------111111-----63-2------1-1-11-----11--------1---2---------------3----52--1-1---111----1---------12--------------------------------1-1---------------------------1-------------1----------------1----------------------------------------------------------------------------1------------------------------------------------------------------------1-1-----------3-------1------------------------------------------------- 11--31A-53-11112163H575EAIA5443227453434443221794PD7AJ233J22123--11---11212------2212-3-2215121*11-1--2121-1q2zKMRNLBHKGFLKHugJjM**c5kUkEGHGSLMZP8MGABREBQJIEJJ79CFJB62867934Gz-AK2P422136896D515134219 * f.1.4.1 Bcl-2 inhibitors of programmed cell death
[ 575] 22-1111121112211-111121111112112111112111211111112221311-211-1111-11 2232432233222223323-2233222222222222222243332233222233332322442242234422222222222222222222222222111222222422322222222222222222222222222222221112232223222322222322222222322232222222232222222123333333333343333344333344433353333333334533333333333333333333412111131113322112222223333333333333333333333333333333333333353443233344533233333343332333333336224234333453423344454122221222222223222342222222222222222224-2222222223225222222332222222222223322222222222222222222221111111111111111111111111112222223443233333344555332255564334223232232322233322342222232232222222222222222222333423333222322222232222422222222222222223232222222222222232232222222232322232222322312223222122232222222333223233-221322222222222222222222353232222222222222223223323212222222222222222222223233222342222232222222222222222222222333234323224243322222222223333333333334322222222222222222233332211111111311------------------1-2----11211213222222 23----2-2--22212232-52342522232122311111111112-11222332115211212-122-222222131122-1222131241251241211312131134632331221111217133-8F5-3192--231121112114211115132--172224--421421312R12112A5341422122112 * d.68.2.2 Enolpyruvate transferase, EPT
[ 576] -------------------------------11-----1111121141-------------------- 1111111111111121111-11111111111112221111111111111111111111111111111111111111111111111111111211111--11111111111111111111111111111111111111111111112232553322222222233123334222222222222-----11122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222222222222222222112222122222222222222-21--1111111111111111111111111111111111-11111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111211111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111-11111111111--111112111211112-112111111111122222122211111--111111111111111111111111111111111111111111111111111111111111111111111--1111111111111111111111111111111111111111111111111111111111111111111111111111111111111311111-111111111111111111122212222221121 11-1841-B582EH797C75999BAA7888888989776777788896787B7776A768774553333644354432343667966565EB7EEC75795C4766-36AB756B594455456784D4Df9295F44557357255543965D47555288555t6777C676F2841923266GJIJ9IK3146782 * a.149.1.1 RNase III catalytic domain-like
[ 577] --1-1------------1-----11--111111111111111222111222221-1-1---111211- 1121421333321122222-21111222222111114211122211112111111112--321132355311111111112212221144453323-112212232312---------------2111111122122222111312132222222222322224323332222233322222543111111111111111121111111211111111112111111111211222222222222221111111-11111-1-221111-11111111-------11132222222222-------------111111111212-12111111121262112111211--1331122121211111121--2225322233333222243222223233333333333-3323333233323444224222332343222433331252222222222221353---11111---------------------2444431222112223214443113144452222212221111311211112211212211133333333335432335621134321555144434333322224312332333333333333333334344433443333534553333353233333324332-1-443311111133553333334334333-3333334334333333334333444444444444444444444333333334-33334333334311241111133334343611111111111111411131123425344546646566655566223223222232223333344444334444444433331131111111--------1-1-------------------------22322222222332 12--334-4111111121-13324152111111112222222211131122214-1112111111111121111111-1111111111122121111121121112-375748C74A2546344BI4F4FV516384433835C34446564471856A798272212572444D2443Q2223466491554266853 * b.49.2.3 Eukaryotic ODC-like
[ 578] ------------------------1--1-11--1-------1-------------------------- 1----21122221222111-1---1-11111122221----111-1-------211------1-2------------1--1---------111-111--111111111-1------1--1111-1-11111---1---21------1--111-----1-------11-11----------1---------1-11111111111111111-1111111111111-------1-111111111111111111--2-11--11---111111-1-111-1-11411111111111111111111111111111111111111111--11-11111111111----1111-----1---1-----11-1-----1---211111-11------11-----1------------111121111---------2----1--111--1--1-11-111111111--11-1-1111-------------1-----------1------11--------------------------------111-------11---11----1---11111----1--1111----12211-1--1--1-1----1--1----------------------1---------111--11---1--21-1-------1--------------1--1-------------------------------1------------------------------------------------1-1----------1---------------------1------1--1-----------------------1---1-1-11-----1-11-11111-----------------------21-----------------------------1-1----1-1 1122QQ9-C25198FCAA889978AAADFAA8ADCDAC9CA8976699DEA7DAJD9998AB874768336896745145666795AA99GCABEFB9B8669B834MJIUBKAIML8B7DGH8SMBF8e*J3LCSB68EG8BGA8BEC9I97K7DCCD9F9FLEI8Q8776DBF69ABdCBDB6CCGGAB9357I9D5 * c.15.1.1 DNA-repair protein XRCC1
[ 579] 11-----1----------------1--111--------1-11------11------------------ ----3-----------------------------------------------------------1---12----------1-------2313-211-------1331-1------------------1--1-------12-------------------------------------------1----------------------------------------------------------------------1-----------------------------------------------------------------------------------------------1----------------1------2-11-------------1---------------------------------------------2---------------------1------------------------------------------------------------------------------1----------------------------1----1------------211-2331-----21-----------------------------------1------------------1---------1---------------22--1-----2-----1--1211--------------------------------3------------------------1--1------------------------------------------------------------------------1------------------------------------------------------------------------1----- 431124E-cLABFGU-11111111111111111111111111111111211111211111112-1111-12--1112-211111--1221-31443211222166615HFqRPKLISIFKEHLOXPEgI**Z1wUmHJKGUEIVKCMLHHSDDfMOaJRDGIHOM46B339v*NM3LMI*11121GJNM1HF34HUFHF * b.1.11.2 MSP-like
[ 580] ------1----------------1---21--1--1---111111---3-----3------------1- 11213--22221-1-11----111-------------1--223341--2----231----221-4121431----1------3----------------11-111-1-1---------------1----------32246---42642133211--------22115532------------425-1----2222222222222222223222222213243131111115212222221222222111111321--------11--11---12-----------1------1-------------------1---------25214222222212125112211224-442-1111234-2311-112-11-122112-------2221112132111111111111-32222221111-11-11111111111-2-2432222212-----------1-1----------------------------------21------1----------11---------1--2----21-22--------------------11111---2--1--------------121-11--21111461---1-1-----------------1-1-------11---1-----1----------------2-----------11------------------------------------11-------------------1------------------------------1111--4-----------------111111----1111111221111121222-------------1------1-------------1------522----111111111-------------------------------------11-1 1-55EC4-1---CB345353332432133-111-2-13233332325533545654612333235343162252223132255533---24153481123-725121156*GJCCILDBD9GCCQJDMBg*H-LFZBEEBJBCFDCEECBF99JBECLKfYDPNKR9aLb9Lj*81EY2----E1BQGP2ME1IXRTb1 * d.111.1.1 PR-1-like
[ 581] ------1122222222-----------1---1-----------------1-----------122--11 12211-1-221------12-1----111111--------------11--11-121-------1-11-12---1111-1--11-1-2211111-111-1111111-2131111111111111111222211-12111---------212244-11--11--21-11243611-11----111--111111111-1111111-1-1-111122211--21111-111111112-----------------11---1-1111111-1---11-1-------1111----11-----------1111111111111111222---1-------------------------1--1--11111-1-1-11--1--11122311117515214542111213111111111111-21111111111-11111111121141111112232221111111111122211121111111121--1111111111111111111322223333444454355543353555635642243513334212222212423323322421111111223123352122211122221121133321333343221211122222222222222253121112311122221223222323222322353321-122111--11132332332222222222-232232222222312211223233342333323322333333342333222112222222222221121111-1222211332111111111111111112111121142777744243243241321111111112222322222332222122112222111111311122221111111122----------------------------11--1-1-2211 ----561-334133242212322333233322232223443552323523333222233432332253333252423-22422121221262224222223122623424LECCECD9878999DE8G7R*E1GCS8B69E99978B967E89G6787A7KVHL9QDYLah9EBJ13-2J-112354662142223351 * a.250.1.1 IpaD-like
[ 582] 11-1-------------1-----1----------------------------2--------------- 143-4------11147787-7133D59989975343324415-612-11-1-1211-1--422-9156661-----------3----------111----2---21-1-------------------------3-11112---3-12141111111---1--1-1-2231------------12-22-----2333346432556545-422116461113222211-1-21-11111111111111111----1-------121111-1--1---11-----------------------------------11---111--11-----------------------------------------------2124113-----317452135243322212121222-34122323323173323327624656121-12424411311111111134-3-11---11-----11--------------1--111222132232446435111155232312247333854-2111232--434352-31--1-1--------1-2----2---11----221-1122212-1-1--4521-------------------------11--12--2132-1111112-111111--112---1---------21-2-3-1112122111-11111111111--11111-23321111-1--------------3---1111--211111111111---------1111-13-1---------------1121111----1241315424121211--1----1------11-----1---122-1-12-11--------33--11------------------------------------111-1------1-- --66gq--A41-2239CK7MGIKUfVV997BABFF7BA6A99998ADIBTKNVa8CJH79A93-6314-12223262412224356124BG8C48924326-2544-896F877768543546484556Ih6-7653424766732622372-8586363313A356557C32581621A324369285K3D45F9A64 * d.86.1.2 BLES03-like
[ 583] -------------------------------------------------------------------- 333-322222222222222-23222322222233333544234322212224232111115522324644321222221131312111444214111--3443236415---------------2222212222222233---215333333223312122243224673111-22211-11232111124346666666666666665444446674434433222222443333333333333333333332223422323222233322222333333333333333333333333333333333333343333333331212111111211211211111131111322212233222521111212144-766421221555655545555544444444445-7797897765415555666666674534435444443451111111111113335------------2222122211212----1434534444489989856665885677774797577882233343444464552333322342222222222233454532133222222133333333355455444122131121121211111111111122553233322233565444244462422422--11213-1-11144333434444444444-4344444444444234334444334434333433434434333443332333143444444444411131111122223552433343313332222423333333334444445335555543555---------112233333322111444444433344441-136666661111111131--------------------------1-11111111--32 -------------11----1------------1---------------------------------------------------------2---14------------2--11----------------------------------------2---------1---2-1--------1111---3--4--1--1---- * d.2.1.10 PBP transglycosylase domain-like
[ 584] -------------------------------------------------------------------- 1-1-2111111---3------2--24-----132221334-1111-2-----1311------2-2-2122--111-------2---------------------1-------------------11---------1---------------------------------1------------111--11-------------1----132--11-------2--1-----21----------------------1--------------------------------------------------------------------4-------------1-------1----1----33-------------1----111--------W67--57387511111111115-22222222B1--14433396336653---46741453241111111111111-1-----------1------------------1-----Q****12232121111221111111121D****9G433I8sji*e*4**4A1-----------------22----2-1------1----------1111-1-----------1------------------1-1--111----------------------------------1112--1-----1-1-------11--1--1-11-112111--31-11111111111111112-----------------------------------1285----11--------11112111-2-3111111222312122222-------------1------11-1-121111111------------11------------------------------------------2------- ----11----1-12-2112132312-12111112111-1--1111122111212112--211111-21-1-1111-----111111---12111111211111111-11-7211112-11-1--21-23383123311111-111-21--1--11---L----1-31-26---3--11-5---11421l3132112-11 * a.288.1.1 UraD-like
[ 585] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --11**8-----225-12------1-11-11-1---11-11-1111----22111111---------1-----1-----------------21-121-11-1-31--5I**VSRkNlSRRPQIK*tQUR**q4wc*ITVNjMOcfGSNKFqMPmMVMLQ8DNFDbF7GEEFDFGA1NI241-16211121311535642 * g.3.11.6 Integrin beta EGF-like domains
[ 586] -------------------------------------------------------------------- ------------------------------------------------------1-----------------------------------------------6------------------------------1-----------------------------1----12-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------5-----------1-----------------------------------------11-------------------------------1--------------------------------------------------------------------------1-------------------------------1--11-----1----------22-------------------------------------------13----------8-----13--------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------122---2----1------------------4--------------------------------------------------------- ------P---------------------------1-----------1---1--------------------------------------------------------2--ivxzvoYbXKSXXLzwUwO**m7pW*QPQZuRfgJNVSacdSG*ftfVfAILQkbDGDVGuDGR5--------------------2--- * b.121.4.5 Bromoviridae-like VP
[ 587] --------1---11-----21-----------1------11----2--------1------------- 2-11----1111----------11---------212-1-1---2-11-112-1--------1--1----------1111-----------1--------13----------------1--------1-----------1------1----------------------11---------------------------------------1-------1----1-1--1---1-11---------11-----------------------------------1---1------------------11--11------------1-------1---------------1----1---22--1----------------11------2-111----------------------1----1-1-----1--------11------11-----11111111-1-22-1------1111----------------------1--1-----111111-2221---11322121--1--------1---------11-1-----1--------1-------1----------3-1-111-1---1-11-1----2-------1--------1---11-1---------1-1-----------------------------11112122223222222-222222122222222222222211-1-111212-12221112211122222--211111111111--1------1111-1113----11---1-----1111212111---------11------11112122-21---------------1132322111------1-11-----------------------------------1--------------11-- 2533769-RA8274AEEIGCEDDKFGE9998789A89BAA789978EDDCEHFL9CEA899866A194485355488487267776566BNCEAAH758678C83619Y9IACCE9M9878899PG8O9h*D2ODU899BC68B78CA87E87L8H89989CDE8ELL9CeOQC837A8b757457576H35F8LHgQ6 * c.60.1.2 Histidine acid phosphatase
[ 588] 11-11123323333331121111111121112111111111112123122222111111111111-22 2234422322222324444-46224A444443A999345646554222222243232311234242455422222222222241111122331311---1211223312--------------111111111211333332112421152121233111331221211221111111211113221121132111111-111121111221111111122411211111122111111111111111211111111221111111222211111111111111111111111111111111111111111111111111111131121111111112111111122141112213335372133522111-1211333122222135451114224133333333335-4524444339626665665666874611136455556571111111151113134222222222211111111111111111113122311111145545422222443633332345211311211233111124214121151542111111111112211221122222222-21211111211112221121121111111111111111111111221112312123433322322222223233---1124------13211112221211122-2222211222212222221222111111111111111111111422222222111111111111111-111111222211354111111111-1111122232221214188889887989884455111111111311121111112111223333344411111111111111------------------------------------22122121111121 1111431-411-22332333663748544333354443332333234325444555344445211111-11111111-1111111221148324393222232566-18357C4464124124153242CR7-5353232412622513253242644624489326625456421643l11135F6BF3852432215 * d.128.1.1 Glutamine synthetase catalytic domain
[ 589] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------- --11--1-----212--21213332132-3222-1-----212-1-4311132333-24244--1-----2-2---1-1-1---1---1-85-2431--2--123---I1*WNUNYYXRPTVVM*kM*R**lA*e*YQOQTVgaPIZOJHUKK*MNQKN96EANIAGRIeC7I841-156131347CPH1F41A1-227 * d.10.1.3 Methyl-CpG-binding domain, MBD
[ 590] 11-----------------------------------------11--1-1------------11---- 2362622222222253333-342234333333344445CB2733332231113633321154226498752222222222223333334323-3223--232225232222222222222222222222222222333342224344344442233333333333654563333333333333332233112133333333233333311111133422211222222221122222212222222222222212112111112211222221112221111111122111111111111111111111111211111111121133222222223212332222222321222222212211111112211332222422222233442223222222222222223-24224332232233332332322232222234323322222222222322222222222222222--11111111111112122-2223233324734445557776566888837734555322323323223222422222322322222222222233323222232242222212122131335355222112122222222222222222222223332332222322222232222222222331-22222------24233232433244443-3123223325343222223433336533433432333333332422222232-3777777477761122222222222224331111111111111113333333222425555344355335343311111111124343333333443322324224452222222233333311121-1-33--------------------------22234322332222 34--211-711111211221121111211-11111111111111112111111121121111121111111111111-1111-1111111311111111112113211412--12-11-1---------4C5-2----1-1-1--1----11-12-11132-1---------2--2484k33344DCAO1IB3442213 * a.174.1.1 Double Clp-N motif
[ 591] 44----4444444444-646444242241222----------1-----------1--1---6644--- 2494412222232322233-32443433333332223345222221-21---233325--23412222242--------283------33322244---22222322-2---------1-----2211211124322244---241------23--------1--2------1---------22222--224222222122222222222222222222622321--11152----------------------2--------------------111--------------------------------------------2A64888888886862844855528-2-2-24-IE68D6-282--22-4125-22222222364444232444442222222222213443384324226224668669464722222222222224444444434424644-----------------------------2242225632454466644444556E4444239BC242522244C24445624242221224222222222---2822A844--3-11----E8E2I3A--22422228-------------------------2222-2224242-2222222722224264242----13-------3-3-2--5554555553-5555555555555555552-------26452666664626226-2325443-------------1---2222222222-2358-----1---1-1---22222232228255554444445442446-------------2-----22-2222122222222222--22222222--------112-----------11-----------1222222422322-2 ----322-633-22322231322232223222222222222222432122222224223223232222112232222222222222-2226222232522322224-25265453442322332542827S5-546322142244234445125133323562322242372442234--21-3252451232253222 * c.26.2.3 ETFP subunits
[ 592] ---------------1-1----------1---1--1-1---11--1----111-----1------1-- ------------------------------------1--1---------------------1-----------------------------1-----------------------------------------------------1-----1-----------1--111--------1---------------------2------1-1-------1-1---1--------11---------------1--------------------------2-1-1------------------------------------1-----------------1----11---11------2--1--------------1-------1-------1-1------1----------------------11------1-11-2-1-----1----11--11111111----------1--------11----1-11-11----------------1--1-11----11-11-----2-----------1-11-11---1---1-1----------1---1--1--------1----1---2--------1--------------2---------1---------31---------1------------------------111-1-1------------------------------------1-1-------------1-----------------------------------1-11-11------1-------1----11-1----2--1--1----1----1-1---------------------------------------------------------1--------------111-11---11---1---1------- C956A98-U77665865559675D8C75464566676767698555559878B857986756555545246444646266556476565685558975544A666746B9aNdXROYIFIFFFHbTEgEy*W3bQrEKECX9HMFBMGEDUCEiHOHLHCA99ABQBC9CDBFA9C686X54457DBDE7FB5779BA4 * e.25.1.1 Sec1/munc18-like (SM) proteins
[ 593] 1---11------------1-----------1-------------1-12-2351---1--1------3- 5Fa19------11-1---------1------13----212121112---1213111-1--141-63441231111111--112-----668A-E33---443359-4A4-111111111----2---------3-55564---B5251-44422----11--42-312-1-1----------322-------111111112-2212121-11-112112--1--------52----------------------1-11---------11-------------------------------------------------------1---------2-1-1-----------4--111-113-----122----G-83448--111--1111-------1111111-111-1111211-111-1221-11--1-111345--1--1-11-111111111223--4---1-----------11--------------22331-----------1--------------1---1----11-21---1---------------------12----31-1111--11----1-1---2--7636E5-1---------1-1------------1-----3--2365-566446466655657656A----1-1------1211----112-1-1---1---------1-----1-11112311--1--------------22--111---2---211-1-22---51111-1111------1---------------------1--211112---1----1-----------------111111----7589A978892222--11--------------11--------------------------111-1-1----7-2 --11113-814-7664657475357443433433333343323563724288A764744545224523336232222-2232223442258463543132424646-4749QTIJIC99689D7NI8Q7z*Q5aNgA8A7M8DG97F887D77M7JEAC7IM7767DWAAhA9883536V32143GBF87B34375342 * b.70.3.1 DPP6 N-terminal domain-like
[ 594] ------1-----------1-----22222222-----------1111211111------11---1--- 312---------------------------------------1--------1------------11---------------111-1213322122231122122723221111111121111111121111-111211121113253222232222222222322323222223222223321121111112222222122322122222112222222222231111112211129211211112111111221122111121111221221212222223111122-11111111111211111211122111332111222432554555635462332322333132321122321334122322111113111111111111111111111111111111112-111111111121111111112111111112121111112111111113112111111111111111111111111111111111-11111111112221221111111111111112211111-1111112-11111111111211111111111222111111211122111111222222211111221111-------------------1-11-111111111111111111111111111111111-2211111-11111111111111111111-1111211111111111111111111111111111111111111111111111-111111111111--11111111111211111111111111-111111111111211111111111-1111111211111111111222111111111111111111111111--1111111111111211212-------1-----------------13121111111111 43226771E564655678747766659776676767877776686758766686678765664534743766544763776887774546A677695567776C752885HA8687765655769A3E4**B1F8C55679577375668856A697456CE57564664736876366T55446946A77I3567653 * a.113.1.1 DNA repair protein MutS, domain III
[ 595] ------------------------1----1---------------------------1---------- 1111------------------------------------1---1---1----1--------1-1------------------11111-------------------11111111111111111---11---------------111---------111-1----111----11---1------------11111111-111111111111111111111111111111111------------------------------------------------------------------------------------------12111111111111111111---111--111211112111111111----11111111----1131111112112--11--11111-222221221211111111311111111211112111111--------2112-121--------------------------------111221115555852444255526667163384446--3641123223-221253311241-------121123111-1111111222221321111111-12-1-1111-1111111111111111111---13-1121112-1312131222221122321---11-212111134223132442222432-43332333244232222222132122243344444444444442111211241333344324343--21-----1111--521---------1------------11-2155453453544444555---------1222411111341222222222223------111111111111111111----------------1---------1-11111111-1-- ----556-7364565686356665766A78757987763666677868876465886287776867664666666776666766664664C986673675446564-7-5IEG9EG67AADB98OGADBR*9-B9G89A8C8EA86A889A769CFA9D88988867578668965777j67464AHOK6IF5669A98 * a.4.5.54 Vacuolar sorting protein domain
[ 596] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1--------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------1---------------------------------------------------------------------------------------- ------4-------1332311111211111111111111111111--111111122311112222233122122233-2321222233311131-1334--11321-17-Wlij*gmMQOPOURzvH*Q**e1yQ*RNMKeNQVNLSQUOrMI*RqRVU9DxTAF89U7CVBKR9-355t3421141221112246588 * a.278.1.3 PSF3 C-terminal domain-like
[ 597] -----------------113122122221122-----------1111111222----------1---- 433---------------------------------------------------------111-------------------121221443313223--332338362211111111112222134333332343222221112322222222222222222222322222222222222222212222122233333233333333333222233312133232222223333333333333333322222322133123322222332222112222222---3221222222222222111211111113222222222244524434434243544433347221222-2355433322342332131242111111111111111111111111111111111-111111111111111111111111111111111111111111111111--11211112111111--111111111111111111-111111111-1111111111111111111111111111--111111-1111111111A21111-------112111222223333343332222222213343335122--1-------11111111111221331111211212111111111111111111111---22612-11111111111111111111-1111111111111111111111111111111111111111111111111111-1111111111111112-----11112-1121111111111111112222222222212222121211212222222222222211111111111111111111111111111332122222222222212211-------------------------22222122211112 3322654-C55245566464555554666565656565554556556655555645666566443453-564334653555445653336D566766565746665289484655474444553672C3*s8-8395544635634542564574754526E3437323263575767Ay77658A56858C5655555 * d.203.1.1 DsrC, the gamma subunit of dissimilatory sulfite reductase
[ 598] -------------------------------------------------------------------- --------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1----------------------1---------------------------------------------------------1---1---------------------1--------------1----1--1111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111--5-31--------------------------1----------------------------------------------------1------------------O-*XqWuaaQIOLORHaaGqX**x-*VkLIJETELaWAMIKLQGIiOfTORLEFCsV41222K376U-12-S324-1---1----5----4 * g.14.1.1 Kringle modules
[ 599] 11-1--1--------1-111111-211112211222122112133235413421-11----------- 1-1-432111111111122-232223222221411113331223222-3112131133--1111213122111111112---11-11233321211---1211112121---------------1212232211222211-----29541231211------33-16321------------1-111-122-2-----11-----11---2211---2111---22222221----------------11-1431246313331211652122313232221111233111111111111111211111111211222111231-112222222323122224424112-2---4111-3-2111222-1--111-112-----1-2-21--11-1-22222222221-111-11-5-2---11---111-1122--2----1-11----------112---1--------------------------------1---2--1-133231-11111113322212213-2-2--11-1--12--14-22-2-11-12-------1-2212-212113122-222-1315242-5--1-2252-----111111---------1-1112223213-1111211111211111111111111--121111111142224533333333433-3333333334333333332686342226455666666566656433333332-44444444434411-2-----21213-11-111123-111121111111111---2-11-1-112-----21111--------1211211111211111111-1-1111111--5111---1----------22---2-212-2-1111-421--111--1---1---1222 1-11111-411-87853336564667722433335645434444236474AA9C65678444324224-3242244624323333354647636575465554498-2825DH6DF14764666BF5I8R*I2ODL3774B79A65875473498845739994142A2224E3-2645*33353BCEL4H767AI996 * d.58.5.3 ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain
[ 600] -----1-----------1--------------------------------1---1------------- -----------------11-1-----1-111--111-----------------------------1--------------------------------------------------1-------------------------------1------------------------------------11-----------------------11-1------------------------------------------------------------------------------------------------------------1------------------------1--------------------2---------------2----------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------1113-----------------1------------------------------111---1-------------------------------------------------------------------111--------------------1111-------------1------------------------------1----- ----FFC---1284A33423443534444343334343333333435444646643645544432334234132345-4433333332246434542334364ABE1M-BOkiZncdTKMINUNpmKgQ**YEfWwCMIJaOTdLESLHGfLD*XRQRUDUNCDBFAPAAX6GC9-2----1-1-114131--13446- * a.116.1.2 p120GAP domain-like
[ 601] ------------------------1------------------------------------------- ----221-222-2--------2---1------211111121--1--3114543332-2--1-27111221--------4--1---------1---------------2-22222222222222212121111111111-----2--------------------------------------11-----1326221221323311214H786861315321823KKMOLJ321888787788888887333392-2CL2-424EC--IP1431242335946555567B87878A7887444444445444424411-444913-4E3333333424-Q--1121-1-21312--------1--199712343-3111212222121111122121111111111112-11111222111-211122122211111111112222111--------1---1112---------------------1--------1111111111112121111111112111112211111111222112112111121211---41111111111-112-333-121-11111-12111121122222211-------------------------11868111111151111111111111111111--1111211-111A544454BBBBCA99A9-BC8ACB8ABBBBABCACCBDAE66232BA8A9A9BB9AABAAA6A8677684-666666666565--21----------112144564622222233422222-2---3133333433333332343111111111-9998888887A99A2222222222-------822111133323222221------1-4431-444145322--------1----161- -------------31---2-------111--------1111-1-------111-----1111---------------------------1---1------1-------2-61324141-11111331115B1-313-1--31121-121-2-12122111353122-11-234112---2--1-----1--1---1-1- * d.112.1.1 IIA domain of mannitol-specific and ntr phosphotransferase EII
[ 602] 1111111111211111111111121---1--1111111----112-1111-1-21111111-1111-- 112-223222334321122-232224222222333344322231422131322332311122243223323211111111-2321112332213131112222221123111111111112222111121111112222211-2132323322222222223221322231224112214212222233133344444433355433243333344433242333333333322222222222221232232424122121214433213343324663333233233132223222223233332223333333333333433365444445454554555333433242332222322434333322142122111123213233222211322433333332333-33133232443-444244365422342221143232-12111111111111143311111111-1111112111111111---113343121111222222222223222232223224443312222233231-2231431322223222131111-111312111225114422434343333222222221122111111213111111121121223321-431-431-11121332222--42121-1111-11111112121122222221222-22222222222222222222223311311111111111111212221222211222222222222121211111111111111111---1-----221-------12121222313121-2122333111111111122211111133-232232222233111111334422221112122-11111112--122111---22112122222121233232213 1211122-532-113342243322323443323322331423323323222222222222212221211212222331321333334442424222212224334511D242334332213132582A18S6-C582112232J2322-132252322435223253321712242243a35533A78A1564252232 * d.66.1.4 Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain
[ 603] ---------------1----1-------------1--------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ -1--211---1113-2--1--1-2-13-13211122-------4122--21115-2-225-3-----1----------------22-11111-534-11----213121-*RRVbjSLPSMARMlPKxF**l9qX*NCKMRBNcTCLEMBUMG*FOROYMKFd*jBbpS**BNR31--1-----13414613--1-21- * g.37.1.5 variant C2H2 finger
[ 604] --111213111111121112121111111111222132222212232211422222122321113212 2321121122111112211-11111111111111111121122211211111221121111112732221222222222323211111114212111--1111141211111111111111111222122111211111221211121123211111111121311112231112112211311-1122221144444233343424311121134311122112222223222222222222222222222211121111111111111111112221111111122111111111111111111111111111111111113332333333323244222222323222223134122322321122-21217111111111323432112222311111111111-112112221221111132422346111111111111111111111111111121122111111111111111111111111111211121111122232233222233233333121212212112222112211122112312211111211111122321331222322311-2121221211211123121121111111122222222212123221112111111113233123333322323211-1121111111122222112221221222-222221222222222222222211321222222222222222212221112113111111111111111222121111315111112111111111111111112111221111312221111211121111111111111-1111111221111111111111111321122421111111121111-11-111111111111111111111111212222211 5333434-B322223343423333435333333333333333332333335444233333134333332334433332333333343333634434423424347415A59A6668D6756666FE8A5IwC-D8G5686C686646766647D59977434CD745736766433254P3534396683645365452 * c.55.1.14 Fumble-like
[ 605] 11111111111111111221121111112111111222111111112111112122122222111111 2223222222222222222-22222222222222222222222222222222222222222222222232222222222222222222332222222222222222222222222222222223222222222222222222222222222222222222222232222222222222222222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222221222222222222222222222222222222222222222222222222222-322222222221122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 11111111522123333332333332233233333333332333331333333333333311333344234234344444433333444353344333333534551251213112112C32318C14-3C3-125-126211213122-12-1221111151312-224311124353p3333588EG3651111112 * d.141.1.1 Ribosomal protein L6
[ 606] ------------------------------2------------------------------111---- 343-2---------11111-11111111111111111111111151-211111211111112112-122211111111----123444EEH93C68---222222212111111111111111-2232322243211111---21731122122221111111113214111111111111142111111311333333333344344221112334111111111111112-1111111111111111111111211211111111111211112321111111111111111111111-111111111111111111111211111111111111211111111-1111111111113211111112122132644333333536344443433633333333334-2252453443426557333444333334334335333346666666658645A43123333331111333313333333333333346433433343353353333336932333334656783386543465335353336464454333433333343845445357464786254597554C4434445411-1111111111111111112111865552455335455555554555445444441-3534431233344444444444444244-44444444444444444454444444444444444444444444444444451444444444444--8445555333344443333333333333333333333333375555554565555545551111111113644444444445444444544444444433G-11----111111111117DF13--13112-11111--1111112111111112232 1-------1-----------------------------------------11-1---------------------------------------------1--------1-------1-----1-13-1-121-121----1--11-----1--2-1-1-----1------2----121--1111----1---1-1---- * a.55.1.1 Prokaryotic DNA-bending protein
[ 607] 441-113577777644--111--12333--22----------1-------1---21131322121--- 1114221322223111111-1211112222211111123512112221222143433411112111312211111111---14331113331-31111111111112313222222222222221111111114122212---43223222222222222222232222323222223222212111212223444444443444444333333443322333443333333344444444444443333433-4-22-3---332222211112111333311111111111-11111333333333333313311133312211-222242312113221---21--13--1-11-211111222412-1212111111121311111111112122222221222-22222122111111111111111111111111111111111111111111112111111111121111111111111111111111112122222311221111112212111111111323211221121221113111111111111111111111122312-4111311111-323222213112113-21----1-1-1-1----------131443311123221211111111111111111131-1211311111122313312222232322-223233222223222222343312112222222222222222232221112112222222222221112111112232111121112121212211122222222123212232233312223133322222222211113222222222212111121111111111-2233221-------2-311111-3-22111222121121---12221111111222 331-561-832-2241332443243443333334443444434343343332213452322222333222223222322322332222223234352322362233-2776AA76676742365CB4A4OeB178D2635656974443485393575665725454637D68855333W4343353785567534643 * d.104.1.3 LplA-like
[ 608] 22-1121111111111-1--2--1-11-----1--11------1-2211212111-11111111---- 32322111----4----11-11--2111111-2111-1111-1-----1--1-----------2----12-2222333112--222--222212-1---14221512-2---------------11111111111211-----1-233522211332212221421325-121111131111111111-11--111111----111---1----1-1------1-1111--2-11111111111111111-12211231221411442121133122234333332221111111111133333333333331332333333-2-11-------2-2-211134311111-31-----1--11-1---1111--2111------23122--22--1122222221223-43334533131-422321-143--221-1111----1112222222244432--1-------------------------------23-21-1125555555544355645555248542313-1544212--21-12111-----232221222---1113242131211311111-1-11-22222242-11----11111------------3323322-111112111211211211121112111--112--------321-2312222222222-2222222222222222223444-1--1333233333333332232222222--222221212222---1-----222221111111311--1-----11111111----1-------2-2-2--1-1111111111-123111111111113213233223----1111221122--------1-1-------------------------1-----1----321 ----778-733-23424445443633533434444334343344333433463543433343433212-42233312-11233334-2435443533233344322-5CAE9E9KEI88777D9PN7G9e*E1EDN6877E899468875A67I899C96AB9A874A584BDA62576I44469A8CC5AA82D9EA6 * f.20.1.1 Clc chloride channel
[ 609] ------1---------1----------------------------1---1131--1-2--2------- 122-7---222---22211-11--221111115111--22121111------2-1-13--12114-2355------------1-----6652-1-----54-717231------------------------1--11121---4-1----------1----------------1-----1--3----111--1---------------14--11---------1------24-----------------1--------------------------------111---------2------------------11---111----11-------1-1--11-1111-2----1--11----3------1--1--44114-------1---------------------------42322--52221-211123-1121---4364------------11------------------------------------131----------1------11------------1-1------1------1----1----1--------1--------------1--------------111124---------------------------------1A3-4-21----11-------24--3--------------------------------------------------------1--1---1----------------------------------1---------1--3-----------------111111-----9------1--------------------1-----------111-12-22-------------------------1-4-------------------------2----1-111-231 --11554-1-11886JGLKDEECEDE9BBA999A98998999A998NMGHNRMQDDIFGFGG47A445296A637666777B98AB544QfOGYeYFEICICQ858--U2P5111437414237787A1IO523282234744822323-64362432*55337AC66884-----67-3172A1eUbhHYPB8TXTfF * b.29.1.2 Glycosyl hydrolases family 16
[ 610] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------1----------------1-----------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1------------------------1---------------------1-------------------------------------------1----------I-*****peJGMIMSNdfKbN**Y-mSpHQIEbHQaIBPKMFPKCmOcLQXCNdl**E5ODCtx**--21-----2----------2--11 * f.36.1.1 Neurotransmitter-gated ion-channel transmembrane pore
[ 611] -----------------------26126-B33----------18M-6I23845-----------1--- 41713---------13212-11111311111132223-2-523-51--111-1111-111--4-4123322-111-------11511-441--2------111143135--------------11-121-1135-865BA2-3A152-D32-333311111111-698D-1111111111117412-23151133333342225323643332223223211651222218521111111111111121111---1--1--1-1---111-1------111----1--------------------------2---------17-16----------2-112-1-112--5113AA86853-532-11----3517552-1111137665347665622131111112-A98865CD13115A947565633533-132215944-3211111111233-1779--1-----------------------1---2413-----12123233----55671111113354689--77463424349852247424274-------1-236A4DA76AG75VICD91DCFB78D7876D6FU3B--11-----------------3-1111846453864491665524455734322383---1335------43223224444454444-2434554435344444543111114313232333333333323444222231-123333211433--2113121111122745--------------1--------1-4534533733451524115---------226475555544244-148479335------5-556332--------1-2-------------------------3222222223-911 ----12--1---1--1412-21---1111----------------------111112-2222------------------------------41-11-1-11-11--1-1--3244412-2122661316I3-555221221245122114126142321---121--213--------3--1-----21-11--694- * d.110.3.7 Hypoxia-inducible factor Hif2a, C-terminal domain
[ 612] -----------------------------1-------------------2-1-----1---------- -24-4----------------1-----------1-1--3--F7I----------------1---1-11731----------2--------22--11---1---1-1------------------22-151--B27-11-------71M276511---------1-1438----------------------------------11-------------------------1------1--------------1--------------------1----------------------------------------------------2--------------------2---1---2----1---------1-1-2111---------12-1-1--1-11-111-1-1--51-1121---1------11-------511--111------------------1------------------------------------1-1--------------1--------1--1---------1--1---11--117----------------142-111------------2-11-21---1--521------------------------5-1----112--------22--------1---1---1-------------------1--1------------1--------------1-----1-111--1-------------------------1-1-------------1---------------1-----------------1-----------------------1----------1-----1--1-----------------------------------------------------------------1-- ----112-------11-------------------------------------------111---------------------1---11-----1------------6*-*LONOWUGGGGIQIYTFbG**P2RPXJHIFOIJNRHKIJIODHLJTSMVB7AE**9BGGGH36DD14421--1--D11*-*1--7F8A2 * c.23.2.1 Toll/Interleukin receptor TIR domain
[ 613] ------------------------------------------------1-------------1----- 1--------------------------------------------------------------------------------------------------1----------------------------1-----------------------------------------------------------------------------------------------------------------------111-----------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------1-----------------------------------------------1---------------------------1-------------------------------------1---11-------------------------------------------------------------------------------------------------------------------------------- -11261C-1--1----1---1111---12-------1-----------3-1---1-----1-------------------1----1------11----11-------1-1*Vdc*pZNDDDQPIvgEjJy*X2jUuHGIBUJOjTFRMEBx9EoBeMMZQ**K*KG9EB9zAB*V--112-21--5946-4--1----- * f.12.1.1 Head and neck region of the ectodomain of NDV fusion glycoprotein
[ 614] 32322222222222222222222221111111343454343331112112222422222221111111 1132111111111111111-12112111111311111211121111111111211111111111123121111111113212211111222213221--232123132411111111111111111111111111111111112113311111211111111111123411111111111111231111122233333433233333333221233423121331222222321111111111111111111211111211211111111112211111111111111111111111111111111111111111221111112133111112122112221323111111113312233312411112111312111211111221212111112111111132111-11111112221123311111111111112111111122111111111111111111121111111112211122221221111111111122222233232222222223222222222222432222232222222223232222322222222111223213131321211111333222232222232111111111111112111111111113223323224333333333333634334333341-2211211111133443333334333433-33333333333433333334343322233333333333333333332333311324234443333111411111111112333333232333312222332232222232333344333333333334222232222333333333333332232232556222211322211111111111132111112-112211111111212111111211111112232 2211564-A74342422523232343422222222222322333223444565735335555243223232233323222232343222274233722253324421363B6753434334434A25438V51564342364564444443347122453323H312333325621443H2342235834833594741 * c.1.9.12 TatD Mg-dependent DNase-like
[ 615] 22-2-122222222223343443143355534-1---1121113223314734133233436552-43 6552521322211132222-23--232222223343323434462222311-112121--66323534664--------2214452215566243321-1212-42442--------------1443534443346666644453643333433332222223333333212111112111111222113-3133333333133333322221233232322111111112213333333333333332333-----------------------------2---211-----------22222222222222---------266-2-------1-21---1---252-161-2333322-1445346245-533122333343344655447564444444444444-33333442453146674755446642233454545533211111111432-13452222222233222211122222222222212422-2332442222333444434355552542242211232222433322252224421231111111134552422534211232223-32344434744543A44121111111112222222221131322212-3112-11------31-----111-361--652311111112321132221211111-2222211221212122223111212121112221221212122211122221-332333322333111422221222231242----2----------333333311141444433436545433441111111113-1113332212-1144435225551111224-222222--------2---------------------------32754454341421 11--221-2-2-----------1----111--1111-----------1----1-121-----321----------------------------1-3-11--1---1--2153656492----3253-42EM5-534212232342--2-23--3342244643333121-3217-2224o4322459AJ-661----11 * d.58.34.1 Formiminotransferase domain of formiminotransferase-cyclodeaminase.
[ 616] -------------------------------1--1------------------------------1-- -12-2--1111---1---------1------1-1111-22-------------------------1--1-1-------1121------111---------1111111-1--------------1--1111--1--1------1--3144331----11121-11-23352122211221221111-----133333333332333333223333332222343422222221222222222222222222232232222322255112212211-77733333333333333333333333333333333333333333333--1121111111212111111112111-111--2211-----------112--56631-1115388B4545575622322232333-22122-4-163-922365446568444372762222226333333332751431211---111----1--------1--11111-6464-8533B77764854444CCB5333333576598713767445648876A447423224422222221233333-----------------1-1-21311325-11----111111-1--------111133554433415552444445443343346655--12122------45353323443433343-4343333333433333335443733226455575455655555533333333-523322222222--23111113222435332332332322223321121312234415455534443363322234343443433334444444465534242342231111211-221112----------1-1-1-------11-----11----1----------2112 --22432-21--12243423253644534144455413334643233337462524211323--1111-2--1-31111--111-11217543343222222253411D-7321-342121-112----482--13111-2312---2-111-11-1131114522276713A23--23E11233634Q2883248463 * c.47.1.12 ArsC-like
[ 617] ---1--1-1---11--1----21211111-2233922214453--13464D76611111211--1-1- 17D1412122313172222-26113A2222237343466625272621211142211211334466445421111-1-1-123--21-3333-422---32121714-1---------------3525454345666666---31433544322334434343333344432222223232232211---1-411111---13-1--212221313-121-11312222121-222222232222223221112111211111212-1111111111111111111111111111111111111111111111113311111--1111111111222211111113111-12-12121---1--1111---1115---3-----25B69212885762222222222315586677A2A1-7113988986A753-1147353545421111111122222313------------------------------136211663389ACC834444AAAC5445259A945C111122221-12-43522412323621112122114352-732211-13---3-1-23--12511215C13--1-1----------------1--111412342213-2-111-----1-1----1------112------14131111222112111-21121211212112212222222211-1123331233233322311111211-211111111112--1111111-1233-5351111211----1111--1--11---3-98A86338356532344-11-11111-21122222254345331-1--111-111--31111222111111111----------11-1-111111-1----1211112111151- 12-1113-611-1122335235255531211312112222233111235545344323423411111112111221211111112111227231352431212311-2D3A2423232222342231427O3-746-222322521321222222113132315211112432313344n4373376343333432135 * b.82.1.3 Type I phosphomannose isomerase
[ 618] --------1--1111----------------------------------------------------- --1-32--11-2-246633-35226C3233358DFD687A-22542332352222222--316-7483165----111----------------------1--1---11------------------------------1----111-1--2--------------1-2-------------22211---12111111-11211111122111112223121---------1-----------------------------------------------------------------------------------------------------------1-------------1-1----2-----------1--3222111115133A-112123222222222222-44233232243-D77843254433463222222121123--------2---1131-----------------------------11251-21111488A74646643353666634E6A67752145443433675583261-1-212----------223-C74---------------2------2-63-1------------------------------3533141-1111114411123142221---------------------------------------------------21--11------------------------------------------1----------4224---------------898997B455E1BBAB5B7D99AB83776---------1-------------11131111111------1-11--11----------------------------------------------11-1 ----FD3-211-22855565345935887-222222766676677743--345912-12211C66222242262422222266686-1-2325432322285BGBH-73BYB8267563768A8NE7E6N*D19F97585D67883865494277666ADGE6M96EI885CK9K1462G22366C39F5A523KEJG3 * a.29.3.2 acyl-CoA oxidase C-terminal domains
[ 619] --1--1-----------------1-------------------------------------------- --------------------------------1------------------1---------1--1------2---111------11--------------1---1----------------------1---1-----------11----------------------2-1----------------------------------------------1-------------11-------------------------------11----------------1-4----------1----2132123423332--------------1------1-----11-1---------1----------------------------------------------------------------------------1-----------12-------------1---------1----------------11---------1-----1---5223451111122763333134495242----1------21-3---1-------------11-----------------1---1------1131-1-1---1----------1---------11-1-1---2---1------------1--1-------1-2------11-1-212221221222-2222121212222222221111111111111111111121211312121221----------------1----------1-1----1-1-----1--111111111211-------11-----2122-----------111-----11111---1-11111---------------------------------------------1---------111-1---- 31331-4-3165743367343173323-1533323426255473344587A3A456225234731313-44554313-1-31143421C473664363211B-13C-124OTQZZRMRGEIIWM*xIiH**o3*TmEIIRNGGeJDJJADTBDbHVIHO4BL29841889D6J45-12162-3--98CA9D62233512 * a.26.1.1 Long-chain cytokines
[ 620] ---------------1----1----------------------------------------------- --1---1------------------2------1----12-------------1--------------111------------------222--2----------1--2-----------------------1--1---1------------1--------1--1-1--1------------------------11111------1---------------------------------------------------------------1---------111------------------1111111111111---------------1111111-1-2---------------2---22---------------3---------1----------------------------1------------------------------------------1-------------------1122111111111---------------------------------------------1-------------1------------------1-------1-----------------------2-------2-2--1-------------------1------------------------1---------------------111111-111-1111111111111--111-------1-----------------------1---1-----------------------------11----------11-----------1-------------------------------1-------1-----1-11----111------------------22---------------------------------------- 332211--C55-75767BAAGHBCCC8888888CCEFCCCDBC888A98ACA9DBB87788866674766CA686BBAAA68886646547675456444496NEM33514MPLPLNHIIIJEJWDEZI**c-bMaAJJBJJIWIGIIJKNFGOKXJFL4AA35965B34V6B32-32-J1-134MIFDAD9111112- * c.55.1.3 Hexokinase
[ 621] ---1111111111111121111111--1111121--------1-1121--1111121---1111--11 4431533233333332244-421152444442222243433445222321213332231133634334443222232211133323223334-2111--342324232211111112121111444254434434222443342336555334333434323422334452222221222131123311211211212232222323224222222222242222111112222222222221122222222212122122122222222332221223221111111111111111111111111111111121331111213112222222213111221111111122111222522121112211131322333422222222242332222233333333334-22322222332-3334333343333233333435333333333333322222332111111111111--11-11------1-11-353323444355555435455443455552445333342233323434355333341222234222222243233313433233264223223243325222324524222222222221111112112232332222342332222322223222222232232--24222------23323222333223322-3222332222322222222333223432212222222222222322322231-222222222222--12111113422344333332221111132223333324222424444444344443433421111221122222222222222233333333332222--32332222111111-111-----1----11--111----1----32223222222322 11--111-843---2121221112321111111221111111111112131434121111111111111111121-1111111112-1-11122221111111111-18611-----1-112--211123B2-218-1122111----1-2---11213-2-141-2--1---413443g22242EAJM1A6212-1-1 * c.129.1.1 MoCo carrier protein-like
[ 622] ------------------------1---11----1---------1--1-11-------1-1------- 5B6111--11-1-112211-12--23111111333311212211-1--2-1-1--11---11222224521-------1112-61112BAC5-622---541-173557--------------1---2123416133333444217342444--1131-1-1421333223----1-----111111BC1-111111111111-111-1---1111111111111111111-1--1-11-11---111---12111111111111--1111111-11111111111111--1-----11---------1---111---1111188164664566545346612216243351233443746771333232114-4322411111335453255454722222222223-44654856553165557687768894423232675532311111111444-2453111111111111111111111111111112445214322274456743333456788884856A44651233274122243462456435425111111122555416437-42-42221-9996D8CA9222233EB1--1-1--1---------------2113262358442654555555555556364571-1444411111143232434443433354-4544353434434444444444432324444444444444444444344453-222222222221111511111111192826---1-11----1--1111111111143222234414333321113111111112A77822222BB688112222222212222134222222--------212---------1---------------5B455868794623 ----111-211-11111111111111111121111111111111111111111111111111111----1--111------1111111112111111111111112-111115211-111-11111111391-112--1-11111-11--11-11-11111112121411311111111H1112121341111131111 * d.15.13.1 Nqo1 middle domain-like
[ 623] ---111112222222112-----111121311---1121111121211-11---------1-11--12 1111433222223111111-11111411111131111121-1121221111-211212----14213466211112222-1-11--11-----1----------2-11-1------11111111---111-1-2123343-----311---221-1---------1--1-------------1122276-2-5444445445444544855555445122-2-1767665242--------------1332133-15415212756646-121133442221112111-----------111111111111113211122223314E55555654533611-2115-13-111--11-2--1---3213-11---1--2-1-11---1---11--11---------------------22-222322244333131-11-----------------1----1--11----------1111-1-11-1111111-11---322213223221111122421111-254422221121131111111221212-1--1111-----1111111--21----1-11---1--1-2-1-1-1-2-1111--222222-1---1----1---113261-1111121111111223311221122----112------45113523443333334-4434433343434443443B7B32232343333333333433362133333--322122211222--11111111111111--11111112111111111111111112311-1------2---1---1111-111-2114333332524411211111211111--22222211-------11-2----1-2112-1122211-111---2-221546552121 22--434-E7312232343533267444534552423333444333244425392433523234534543444444434445544411123232453223224644-2437473469479555577797Mn7-B8C5754D56998544666684552531874727522927623665*66556DDVH6B82255322 * c.2.1.5 LDH N-terminal domain-like
[ 624] --------------1----------111-1-------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111--------------------------------------------------------------------------------------------------------------------------------------------------- --12MS3-----A8Q8B9889889BB89A996966546564559A79999A9BB89A49899AAA6662B8597A9979D6AAAAA8779DBBDIFBADA8ACggo2A15BNRLOWEFCEBDJCdS8OEv*O3QLd7EC8KFILJ4HGE7GA8PFOEII576OGA99H7D9AO577FC8M95595FQNc7Y9------- * g.39.1.1 Erythroid transcription factor GATA-1
[ 625] ------------1-B2---------------------------------------------------- --------------------------------------1------------------1------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11----------------------------------------------1---------------------------------------------------------1------------------------------------------------------------------1--1--------------------------------------------------------------------------------------------------------------- ----336-----1121---1------1---------1---------1-1------------1-------------------------------1-------------5-1Rqoq*ofLPMLRTR**M*P**o6*e*IPQNjMWmJMWTRNrNH*MnWSQGNTIEEEEfDISEQJ8---------------1------1- * d.15.1.4 First domain of FERM
[ 626] --11111-1111212141111--43---1---12413212112111731333142221213---3--- 34-19---------52222-2422432222225656144313151331-2213432-2--421152331412111322--151211115611-111---15-33A13-5--------------12-122-112-2233341--2-22462243422212--1141222121--1111--1-1413--11-3-15565666635665562222116441-15-1111112127-1111111111111111111-----------------------1-12122223--------------1111111111111122---122-11-34232455444344326111652-1144-1421--1-12-212----1297333-----445781134556311111121112-46444647-73-21147445752133322532232221-11111111-33-322-----------12----------------1-3545--211133342453444445333341354346541332447321476454215-22742--------312461445-131153111-48265341545445B2322--------------------1-1661222473-11143222-2211112233145--1-2-2------1122-2-1121111111--111111111-1111111222221-1-1-111111111111113------1--1--------------2111-1312113513---------------11121-3111187777-644512111332112233131----2-----21-2246344443341222--1-33------------3--------3-5-2-1----2-------11-1--1---2322 2112CD1-541344154523343686433323453433233443343334568733443434113111-22121111-112233122212--4322----311211-1E9S6253C55552445573528R5-6564433213563742252-64A8A6B78BJJ3164541243-241F---2-67B64922342113 * d.3.1.5 Arylamine N-acetyltransferase
[ 627] --------------12----------------------------1----------------------- 11111-------1-11112-1111111111111111-1111111111111111111111111111111111111111111111----------1-----------1--1--------------------------22222222223333333333322222-333333331211111211111111122111122222111111111111111111111111--111111111-------------------1-1-11-1---11111111----1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211--1--------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------111111111111111-----------1--112-----------1------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------111111111111111111-------------------------1111111111---- 321143219461116545666666564557767675466665655556656656776667774454443444342554554334434555844565555434587818F4JGHGPHPDDECESA**DcHz*T4NQsCGIDUFENC8FEBAPBBbGIHECCB65AAG7C76D65D61474V46474B8AB6H43238556 * d.68.7.1 R3H domain
[ 628] -------------------------------11-1--------------------------------- ----1----------------------------------1--------------------1---1---------------------------------------1-1------------------------------------------------------------11---------------------1-------11--------------------------------------------------------11-----------1-------------------------------------------------------------1-1-----------1----------------------------------------------------------------------------------------------11111111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-----------------------------------------------------------------------------------------------------------------1111-----------------1---------------------1----------------------1--------------------------------------------------------------1--------------------- 1111pXZ-845-55544444444454444544444445445444554456655555458565545444244543554-4444244444436445453444423433-UF8bKVRUQSMHDJMPLSRHtN**R1UP*JLMMSMJMQ6MJG5MIIyLOMNMIz*DTH43F8DK84QW2324A2233343874351456888 * b.64.1.1 Mannose 6-phosphate receptor domain
[ 629] 11------1111111---111---2111--11----------------------------1111---- 1212311111112132222-211122222221333323531333233322124353332233323273333-----------4-----11---1--2113334333313222222222222221---1----11-57633---33111111111111111111111111111111111111144444---224444444443443444474464444455344322222242233333333333333344432-1-22-1---111111111111111222222223322222-222222222222222222322222222211---2222222-2--222---------2-------1------1122--23-2411222222124223222222255555533444-225225232322233231533343233234242222232222222222221212211122222111122222222222222222236831232233332243333322233333253333333232232222222333222211112222222221224222-2-1----------2231324--113133-21-----------------------1113223323343334333333333333333431-1432212111132222222222233322-222223322223222222323322222222222222222222222222222212222222222222223333333333213232222222222222224444424222324444333333333222222222222211223222223323333333332222222111-222221----------111111---211--111131-11-------------1323 22--343-313-3323222343333333333233333433332333123333433331233332222222222222222221112222233323434333443443-24362433353133333543417U3-53A2313333533332333451742338634231111A43234423e2222468B93654332223 * a.9.1.1 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
[ 630] -------1------------------------------------------------------------ -1-----------------------------------------------------------------1-------------------------------1--------------------------------------1----1-------1----------------1--------------1--------------1----1-----------------------------------------------------4-2-11--------1----------------------------------------1-----------------------------------------------------------1-------------------------------------------------------111---------1--------------------------------------------------------1--1------------------------1---------------------1-----------1----------------------------1--22--1---2-------------------------------------1--------------1--2------1------------1---------------------------------------1-1-1---1-----------------1-------------------------------------------------------------------------------------------------------------------------11-------1------------------------------------------ 1-1-1-1-1------111-----1-11------1-111111-1--1--12--------------------1-2----------1-1------1--------1---1-21-Fvss**tURSRUWZ*oQuR**kFtf*EPROaUZYSGXYPPdOG*WaVXR7F5FCAD9L89K7B55---11---1-2---1321--1121 * b.69.12.1 Sema domain
[ 631] 111121211111112221222222422333421222233233331313212111-1-----2112122 1343211111112222222-2211222222233222222332322362422244332211332212423224444333-122222222221212---1-2111111141---------------21112111111222333332133423432411111211432223441122121122122221244222222222222222222212332122222222--11111113122222222222222122222------1---11-------11-223-------12111111111111-------------112111222-151241111111313124443332221-3223522242241431111-33-31444413313233333323233233333333333-2232232233312333222222223222233333333223333333345534445-----------------------------2534443333433333343333223333333333334444433323444458442443243323444444422342216534355331435-2412324434644473A334544444441311122124413233332123221423323334333234244342--222241--11112221112111212111-2221222223222222221121221121111111111111111111121211-1--111111111-1-1---------1432222211111111211122222211112422223223234332333122222222312221111112111443333333333331122223321----------1-------------------------1-122313333321 ----113-21-11231121-1111211111111211211111111111111-1-112111111111111111-1111-111--111-11---1----------123-5737695676122233353353BQ6-6553342414443323333252775512133443562H32512334m35333GCAG1C8338A854 * d.58.18.3 Phenylalanine metabolism regulatory domain
[ 632] ----2--------2---------3-22--2--27269--622424221-686H-3-----22-2---5 122--229---4-7---22-24--1-23222-24242-2--553-6-44----232----2-2-4-31212-----445348---2-4-DDD--3-----3343-622---------------12464A9--9-4444-61--4-6-58989--22------443-6974--2----------4-------22-----33----2-----66-----5621---4-41-422-44446424444444-2322---4-3--45--286-7-7-2--2-21221143332866869698883333333333333-89673777217--2222-42132-4-552-2---4-922D3--55--745222-222-243A2223-----24212-5--2-2-3333333333----1-------32-----224--22-3-22--1--4-44287888888---3-----------1----2-24-2--2-22----------24---2---2-----------3-21-22132-2--2-4-4322--438-C--C2622-245---4-6215222-6H---8-3643--422A--C3212-2122-2245-423652359A79B7854-2-AA--83B1-2-24-96-B44-A-44-6-19-2--2E534-------216A-3224222224--22--246-222221-22-422-4432122321-3242-2222-222-222-------5----232--1---------293322666332-646686B2----143482142-42-2--22-2-842-511-17-112-244323A252226-2255754448475--2411--f7--------6-5-1-5--5--AC22---4-4HA-5672-4-2------43- -1----1----1--3-1--221-1-1-111--1--1-2121-----121-2114-----111-1--1--------1-1--1--1-1----111253-----1--21-31-5121-111-2-12-31-3-4B33317---1-12-1-2-221--1-11---1--1-41-21A--1-1-5------1-1-1-2-----3-- * d.287.1.2 Type I restriction modification DNA specificity domain
[ 633] ------------------------1-----------------------------------------1- -----1---------11----1----------1---1--------------------1------1------------------------1----------1---1----------------------------------11112----------------------11---------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------1----1---1--1-1-------------------1------------1--------------------------------------------2-------------------------------1------------------------------D7547I2222561112222-7777442252448--55------8-------1----21------------------------------1-------11--------------------------------43---1------------1-421-1--2---------------aJ--4MXUfdfUadUTS-bSNbUNJcZXcQcUWUWWJQNO35GNoaDRRRUUSXXYQRRRVVCGCMFOL--DDDDEDBCCEEE--------------2-----1---3---3----44424-3--2--7866-43B-2353-545------------1------2----52--------4232------------------1----------------------------1------------ -1-11-----1-----1-11-1------11111--11------------1-1-2---11-----------1-----1---------------1--11-----------113----23111--1124-3-6I21115-2--2--221-1-1111311--1----3-2111--1-11---1------1111-1--14--1- * b.2.3.2 Pilus subunits
[ 634] 222131111-1-222-13111226G-2C698A137-221---155-856AMHC145884632225165 -15-2122-1111-1------1--11-----1111122121343235---1222211---12216--54532111122---2-1-1--4432-212----1-1-23322211111121211111-------1-113--76---5311--1111111------11-1211-------------32434---1-1-----------------11--1---1-1---------221----------------------1--1----22--112---------111---1-------------1111111111111-----------1-------------2----2--4-2112-1-133-1-3211--------3-9-----------1-----------------------------------11-11-111---------1--11-11-------------------------------1-----------------1--1------1----------1-1---11----------11-2--51122-----2-----------1--1--1521-1-1-1---1--511114--415385------1-----------------------11-1-21---1-------------1------------------1------------------------------------------------------------------------------------1---------1-1---------------------------1-1111-12-1-----111--------------11111----1-121111-----2----111--11------------------------------------11-11-112--21- --21332-2231-13222152322332222233424211111132246324326334212222---1------------------1---1-22211-----2-253-493WNTTSfMKGIHIQGZdGTKi*P-ePrJHGGTJJdMDMECDQCFcJKMIiAMA7CEOA7CEV1274-4235-12-11551-11--1--11 * b.1.5.1 Transglutaminase, two C-terminal domains
[ 635] ------------------------222222311----------121221--11------------112 2221312433322122222-24--2322222-44443233232332325222434122--333242345532222222112-2222223333-322---23122424-133333333333333222111122131222221112212212221111111111211332211111111111113231111--343333343444444442-5435445332234333333343211111111111111111111313223232311222221111121111111111111111111111111111111111111111111111-32131112122212122212222-132122-13311-112--11--112312233322222234444434444433333333334-223225244442544355455533432423243333222333333332332244522222222222222122222222222222-2322233323333333333333333333323334444522444324334322322254323442222222222333-111113222121212222222223333331211111111111111111111-----22664233232424555533654443542434--4443422-22266444666666666665-5666666666566666666666444446766556555666666666666663-65556555466622422222233332333433333333332233333333343426455555555455555555333323323233324444434433333333322222222253111111222222224421111--1------111---------11111111111132 --------1-1--------1-------------------------------1---------------1---------------------------1-----1------2-1--------1121--1-----------11--1-----1--31--11--2---2--2-1--1-21-2-119121--31-3-41112-1-3 * d.145.1.4 CorC/HlyC domain-like
[ 636] --------------------------------------------------11---------------- 2221211111122132254-42223455555244442233231312212121121212112221412312211111111111211211111111--1--1111131121--------------122111112122122231112135352221111111111311244421111111111111----111113222226433545335131222554222233332222211111111111111111222111121111111221112111121111111111111111111111111111111111111111221112221121111111111121111111111-1--122111111111111--11111312222111111416343234263333323232332-33233533434263322254333453243222523522322222222244241421111111111221111111111111121122214332233155453221222243222213426283513222414115433323332121221122221124111213111311222221222332233111113211111111111111111111111111441212222174343333243333334323331-1111111-11132131322222222122-2222222222222222222344223332221222222212112213111121133333233333311121111122223142211111211222111133424241113233233753233332212211111111123341111141311223333422211111112331122----------1----1-1111111---11111111111111111112211 11--452-721-225247557979G993325343537646442422575D56A8337644432113131133132332132122123329E543534332222523-652B4A88632311455553627K7-444112141264232-252-74632622236331313243382134M223-4968B72812452-2 * b.93.1.1 Epsilon subunit of F1F0-ATP synthase N-terminal domain
[ 637] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------1-------------1---1--------------------------------------------366--qdbaZcoU*pd*g***5***dfYR*gl*dOgaLTxRW*L-1Ig-----2---------------------------------- * a.28.3.2 SCAN domain
[ 638] 2211322-1-111111--1----152242596--1332333331223125656-1212222----213 334-1111--1-1-11111-12--1111111111111222-21212111111---1------11111231------------121211334423111--2638444254--------------152-11223-44111--1112-8GD6A953222242463683567541411111411111121111221222222222122222222113322211111111111111211111111111111112221111-11-1-1-11111111-------1111111111-----------111111111111111111111111211111111112121211122212111111111111211111112-112116122412222312111111222122-2222--13-11211211342-5552665897892154454233339473333333322232112------------1111111111111----142322344356776764322255563333336467777-144422344421331246341243111111111241246645233247111111142536411113513322322222223233333333353511551A4964A866555547755547366456--1431511111165343656777677777-77777777677776767767774422587778788888787786656656521544444444444112512112222226444333212111112111333333324522666676964777646673122-22-1268743333374454333232222222221-11--22221111111121--------------------------1111111111-121 -----------1--1--------------------------------------------1-1-------------------------------11------1-1-1--1--------------------------1--------------------------------------121-11----25217-55-12---- * d.58.43.1 Mechanosensitive channel protein MscS (YggB), C-terminal domain
[ 639] --1---3122222223--211213211411112132322222222226211111-----3-112--12 6964C------2-222222-2222222222222222222253233-231444535533115321A4663622222222-221112111------------211-1--11---------------1111111111112121222412432114112222111323232222212222222222842--221624666666654756666454463675335-4-222222263111111111111111111111111--121--11-----1-1112221111---22222222222122-------------22222222211113222222222222344----213-15324233322231334342111112---------11111212-1121------------11111311--21--------1---112122111111-1-111111111111-221-----------------------------2112222222265555655554443367773864322222222221211112121111-21142-1--1--11132142322122222112-32313232122114325-111-------111111111111--22---2--3112-6333352133113331138-122222----------------------------------------------11--------------------------------------------4---------2211----------------22222112212211112212221111111---------2-1-211111221111232322112----212111---1--------------------------------------2-11-111222- ----762---1-247CGD87A778986885756HGEJIHIFII657CBAEIHDIA9JC7888B33232236422444456344336333AaIGA8C22213933771533D4332222111124222327N2-537-2-21121-1111121-221122----911-------2-11219--1344656B9G9234232 * d.58.3.2 Subtilase propeptides/inhibitors
[ 640] 11-1--2111111111-212111-------------------------------11-111-111---- 443-1--1111-1--1-----1--11------11111121-----11-1---212-----113-212---22222222-22222121133241222-1122223222-2222222212222222222222222323333233243313322111222231221123586212111112111132222112211111112122111221111111111111111211111111111111111111111111121----------11----1--1212121111111122222222222221111111111111233122333-13214111111131333221111313-13112233433522432221-22433222121111--2221112121111111111111-1111111112312111222232111111111211111211111111121111131---1----1---1111111111111---11-11-13332344444433333444344443453323342233332344443332223222343333223211233323211111--3112156565565744644145222211111111111211111212133563252522136555566655555556565212432211111155454555556556655-5555555555566555555656555555555555555455555555555555254555655555523332222222222353344531342222422333333333334233343333444433333222222222256574555566677233232222222223324323333--------1-1--------------------------11--1-1112522 1---1-1-11112122243354424343242433323344433322422337442333223222352224223433224221233322235523322223482447-38122---1--------41-21161-1------2-111-1---2-11-22321-12141-3--226121-11C2112241153531-6545- * c.1.10.4 Class I DAHP synthetase
[ 641] 11---12111111112-132231111111211312---1--1--------221-111----221--11 1132721233321242333-33223433333322222483242225211231323225--222232444411111111-1114113331111-1-----1211111211--------------12222223222211111---42221111111111121111111111111111111111122111---32322222222222222233332322232322121111113211111111111111111121-----------------------1-1----11112111-1211---1-------------111111111----11-------1--1-221---1111-142--1211-----1------21-1433311111214331122211111111111113-11212312343134412333341111132213111112122222222211111221111111111-1111111111111121211112112534555544634455337744442353A6B871244221122421155225112122222222211211123422-21-33----222241311111123-2311111111111311111112111211221233223232222222222222233222--13222------31111113333333333-3324333333333332333333223313433333333333333222222221-111111111111--1222222222212522-----1-----11112231222232232222222222222232211111111111213222222222222222222221111112-222222------------------1------------------11-21-1211111 321-652-7211665555344656766333333333533343343434354454464543535222211233221343332111112334945645233455223315248643356233234495362En7-71B43555357547525732433A4437855544648D88455553i34254B4884984154525 * a.103.1.1 Citrate synthase
[ 642] ------1-------1--------1153---23------------1-2-31215--------1-----1 2443211211111212233-31--1433333252322373-2324-113-1-564213--342-1131133----------251-322---1--221---336434311111111111111111312454222514556611124233111-3312--12-11214253-111-11-111-112-32---6-222222212-3122211-11-12321221112-111115--22221221122211-321111-1--11-1--1--111-----111---21111-111111111111-------------12211-2222-21--2222222-2--------11---11--11321-2------------46211111----4358652334223--111--1-1---241413-321-111122422312242213352312225--------4--1132---1---1-11-1121121111111-11--31121-277356445554444366675564436686372234565243278754-3527342-1-------211134433162633262331333535221235245311--2---11-2-1-------24243225533333433525344245344344553953--241922122222314323333332333-333333333333333333333222323233333333332323233332333324333333333332-132222233334231313322312121322322222222227453344434523226322-21112112132222222221222533343434523234353221122111111112--1--11--1---------1--1-------1------3412 ----336-7343112112112--1111--112113-1111--1------2-231111-2121212-2-111111-111111112211112311112---1-11342-2737165346534325355293Eg5-A7B2333515333222261262544434222221-111--5--B8A758386FCCD2DA76C5559 * c.46.1.3 Single-domain sulfurtransferase
[ 643] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------1----------------------------------1---------------------------------------------1----------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-----1---------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------ --11547-733-12312211111111111111111111111111211111122311311121132222123222223123212222333-62221A3333232323-762QQbTRaYMNQKNQM*xIqH**t4*V*JOKMVMQfNGQPKLZMJpJZPPNCKGGGEE6C6BF14871454L564446FHN2L53-47694 * b.34.9.2 PWWP domain
[ 644] ---------------------------------------------------1---------1------ -123D54455443465655-5L4466666665B9DE98BD546F54434332555115114362654DDA6111122212652-21112221-122---25232432-6111111111111111222222-121111111---511121112--111111111111111-11111111111133311---43734456456456556532556954453485545334357621----------1-------656633531315466223122325323--1-21------111-11-1-111----2--1--11---2-1-142584445675563AD33142272343-18217422122-122211--4211333111111221211332322222222222221-12122632111-133311231122131211222311212-------------411---------------1-------------11-11124232322322222223384323222245245212443112224212211111211233322323211211--1-1-323413533444333623----3-332321222221-12111111121--522222-----1-1111121122221-3112111-2---1------46333435555555455-5556555555555555554444332233333333333343333334545543-355435555333---111-11----1112-222222122212--111111121--2-44443444233332433----------1112111111112233333333332222----111122--------1---------------------------22112131111-13 ----14--------------111---1---------------------------------1------------------------------------------------4C8993B344353728A454BN6-95F5632724A4339697335264B82---23--------2----1----2-1447-61--31121 * d.3.1.16 NlpC/P60
[ 645] -----1-----------1------1--1-3-------112----1----154431-1121-------- 357-A11----1--34411-1222121111111222214-2774-2-11---465-11--2333211BB9312221---2133-21141222-7112--1423-4341611111111111111-----11-1-1-1222311132523333-22--2-----2-114462------1-----36411231556A9A9AADC8ABABCC676686BAC647A734111212FC-11111111111111---1-2-2-11-1---22--1111----233111111121111111111111221122222222211222-1111356CB77778878794AAA7888B64-182363447643376422432223-33221-----12B865358766711-111-1--4-52722443252-544245324634543-1-1--1-1-21------------16-111---------11112-1--1111111112224211342163373531---22532223113344232-2332421212324211-82---11-------3333543-2-12351324454343353412111268131111--1-2---2--------31-21111-44551213111111111-----111-3---432-----------2---11--------1--1------1-------1212---1111----------1--11--1---11----------------41111123222-12-111------------11111-1---2611111342-1211-222---------11---11-11-----33322222223333--2-112222--------1------1--------------------1--22121113121 --11--1-----UOC13A764553733332222656343444332254357877AAC75556111221133111122222111122---4563IAB34355H6SHa1-72C-11211-1--------1--7---1----------21-11111-2---2----1132--1524--1-21-1--111-11821-251242 * c.6.2.3 NodB-like polysaccharide deacetylase
[ 646] 112-1311123212223333422554475823437222344315737735788345654662342-12 45L2F32333313173344-432264444445477744764GD976313536565412234572967887915663232-4-3--112141312212--2345355622--------------124164232354AAABC-21A45675788331123432235237577242222343212-12111--3--222226343323332-1----333211--22-11---23-111-11-11111111--1--------------------1---1-----1111211-----------2222222222222111121111-21151-----------1-----1--111151421111552-32211211-4272--2-----32254--22152311211121223-5445665414--41125343342322331112-1--2221111111154443245------------------------------122-42---233433471111--471111-24643322112232133111214-1-34----1-1-------1342143911-1161353264944594643554719--1----1---------------1143113222-2-11-2322-131112-111-22---11-3------1--2-1-1--2122111--1111-1121-12--1--11--2--1------1---1------1-----1-1-1--------------111111----5-51-----1------------11---1--22--113421-121--3231--------11111------21--42254552333333--427711---------------------------------------221-1111127-3 1112222-21113323213233343322222224322222222222421111111221122232311112-1222-2-1113322421132-2232111132141214B-648554222113317B293KX61C4823325124312322521614333-251331-322132-11123G32312345922433241D4 * c.68.1.18 MGS-like
[ 647] ------------------------1--11-11---1------------11111-------------11 2222411111111122233-321122333332222222322222222211114222211133212232221-----------212111------------211122322--------1-----1---------3-11111---21233333211112223222222433312221112121311211---3435555556535565453533345544444545222222851222222222222124222222415512212333344211---111---------------------------------------------11-11-11---111-1---133-1---3--2-21---------------212222222222553442224444433332333333-33433433242222234443333355222223333322222222222233133341222222222222222222222222222232242322222222222322222236222222256333222222633333623332233333222222222222244121-1111112222----1-1---222233411------------------------543343333333333333333333333333333--342333333344343434444444444-444444444444444444444444444444444444444444444434444324444444444443333222222222533333333333333333333333333444433333333433333433322222222223333333333343344555554445544443------------------------------------------1----------52-1 33--222-72212322222222222123323222232212222222222232223222221222222312322222222222222222212222222222222333-25234223211222223341236F3-435321221232222222332433232122211-224513322332S2223375591455352323 * b.124.1.1 HesB-like domain
[ 648] 11-1111111111111--111112111111111111111111112111111111-1-111-1----11 1112212222221131122-241124222222233321B712231-1111111321111142311252211----2-----12111112212-111---221111111111111111111111111121111121122-111111211111211111111121111111111111111111111111---1111111111111111111111111111111111------1111111111111111111111-11----2---1111----112-111111-------11111111111-----------------------21111333322412112111111-1111-1111111211211111-2-11111-111111112132211111111-1111111113-22322411111113311212221223111123111111111111111311111121111211211---------------222111532235443566656655566644555554777374411442532432322222233111321111111221237122121222222221212311122112112112111111111111111111111111222232211113122223123222222322231-1222311-11111112111111111111-1111111111111111112222111111111111111111111111111111111111111111111111111111112121-32321211111111122222221214222223322234431222111111111211122222232222111212211111111111221111----------1-------------------------11-22111112111 ----332-31--6584658573786866679786756545655665565777875665657562723413115233111123344421199863584374572211-274842583C4644468AB3B5Mp9-A9F32347368827345933C65658AHR2767123153252111291111198AI8HI2287DE1 * d.115.1.2 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
[ 649] -1-------------11-1-----31111---1-----1-----31-2125541--1---11------ 113-7211222132498DD-D577H9EEEEF978981474-534-1---11--24--2--464-6264251-111111----321------1-------1--1111-1----------------54-4531121323324---2-542522344113111214417324412111122111111111--2---222223142233233-----132----12--------1--22222222222222---1-11211111111321111111111-11122-111-11111111111111111111111111---111-------131112122-1--3441111-12------1412-4--11----1---1-12224-----113331124222322112221222---2111--274-3336222422223231111111111131111111151111-32------------111-123221221----322421211-11221218222265314444233332211-11251245352224132331-322-----1-1--221-1342311122----2131343111122481211-2111111-1-11111112-1113221-22123113111111112111111-124---1244------21133221111111111-111111111111111111122223241112111111111111121111111--111111111111---3-----11113352122211--11111--133113-31111122223332222222123212122121--11122222311114423233333------2-221111---------------------1---------------------------- 2---6A3-722-54547674342566944422246345443442226685568767B666772242323411223121111223221116G779FB22164A4566-4N3O1421122-22-2-341--6C4-555112-41121241123--31---22312A53-212-A49256AB*99958ABAN3IF9BCA868 * c.66.1.18 Mycolic acid cyclopropane synthase
[ 650] --1-1-1-1111122-2-----11--------11-212-11113--11-133---1-----11-2--- 1------111122111111-11--21111111112112222212-11-1--1231112--11-1--1-1-123221221-11-12223111-1--1--1211--2-2-11111111-1111111---------1--1111----3-225--11111-11---11115222---1-----1-------11--1111212-111221112-1----12111111112-----11122121111222212-121-3321333123233--33-1-211345111----2--11111111111-------------1111111112---3444454656462222311142121-11-----1-1----111-1--1--1--------2---11--1-111--------------------22-------111--1231---------------------1------1-------------------------------1---1111---------------1-----2--1-----1---111-2-111122-11--111-----1--1-1--1-2----------1-21-1221-------1-------2122--111111-11-11-266-------1--2-211---1-----1111--------1------1-1----1221111111-211111111121111111--1--1--------------------1121111-----------------------2121--2-----------------111111--1-2-2232-1121-1112131----------1111------1-11------------------33--21----------353321-1122111-11-32111222----------2-1- 6599735-M8459AC56688877868744566554635757468776766888485A65553463443-532424832554434454465D8674B76655C8HKL38H868C6E8DB99857789C6CJ*71M6P55CABA9F466AB499CQC969F28IB2369F43T795559A6s6357AD9EK8DE7EEIJH8 * c.108.1.7 Meta-cation ATPase, catalytic domain P
[ 651] --1-1--11111111123------------------------------------252-2-3211---- 112-4--1--21211------1---1------1----21-2--3221-242-243-----2321313457211111--1---1-----1131--------2---412-4---------1----------------43322---511--2----------------2--1-------------2211122-125-----1-11--1---3466741-1-33-2179AAB9A-1-2222222222222211112781-562-717BB--693-5534688223633454477665564635444444444444444422-544C1--7B222321311119---2231-22-111------1-3---1321--3-113123-------322---1-111----------1---2---------111211223121-----111322211--------------2---------------------------------2-1------111--1-2222--22222212--21--------1-------2------1--1----------1-------1----------1-2----------27-----------------------------1161-31---11111111--------1--1---11--------36751813223344444-23343234342422333348A89A12-222222222222222252211233--611111111111-------------1-1-1---1-------------------------1-----1-1--1111----------11211111121211--21222-1--------1--------------1------9-----1------12------2222112-11-221 --11113--1-----52244774323211---------------1-3353365743212111----------1----------------584243--1-1-1-----2B4XCHFKEG79AABDCI97EBImC-BCF796BG7DDB8D8A7D47LACBBD47Y-7I7H27DE3351-332B1122BGSdj4rM11CIJI1 * c.1.8.4 Family 1 of glycosyl hydrolase
[ 652] ------------------------1----1--------------------1------11-1------- -11-51-2--12-----11-13--1111111-----1-1--123233114312111----317-213465-1111-------1-----3242-822---2523242445---------------21121111112-11111112132421111111------21-2113-------------11---------3333333323233221-----343---122311111-111111--11111111-211--1--------------------------1112212--1111-111111121121222222112211-222--1--111-11112121----1111-----------11------------32-74221---11---------1-2-22122221112-2221221-24-32113243333531-11-31-222212111111111-1121122-------------------------------131-111113443331222133122333113314333-13211112212223122221113---------123311224--1---1----312--1---1121761121111---------------1---11144-332424334333343233323322334---1221------1123-1-1111111111-111111111111111111111111--11-11111111111111--1-1111-----------------1111111111125------1----------22112112221-333313422313123321---------333611111654444434445222----------2244--------11-----------11-111------------11------613 343457A-G58-1283464577495975554444445333443435433576865564565515844318458464423435667722267645543233-556991ANMIDCBCIA6535786DD7D7Cg82A9C3737B58B958486967A7BBA76A76GA53D45147D73875c8766665892934AHJII6 * d.151.1.3 Sphingomyelin phosphodiesterase-like
[ 653] 112232------------1111221111----11-65114222-111-2111111112-2--1-1122 2311221222213121111-12--2111111211111121123111111111111111--2221212115311111222359-22222332312111--2222222223222222222222221222222232224663111131533233111111111112222542211211111111111211221142222222222222222332222222333311111111142211111111111111111111---11---------111-----1111111111111111111111111111111111111111111111146466444444455785555454474432234-65542511223334353223222212112224231225543333233333332-3465543325111222543312342212233244433223333333333322532-----------111111111-1111-----12222222123333334444333344444453343332222222222334352244421222322222221112244B8B52522B24523C8B858A68223232453354333332322322222244342433342324222254343445344345763481-2133211111142223223444344433-43334443434443333333334552222332332233232332333333311333233333333--12111111111423123332222111122222211211222323333222333222523211111111123446444444445543121211111111116233222211111111311-----------1------1---11145123433431312 1--1111---1-111--1--121111-------3131----------221--31----11--1----1------12--1----1----------1-----12-22-13324332111-221222311427M2-3291-11213112112111141-113--11322-----14412-21D113111233-22113-113 * c.1.28.2 Oxygen-independent coproporphyrinogen III oxidase HemN
[ 654] 66666776666666662554465322222222433234233233333333333332446322224222 -1--2--1111----------1---2----------1142-22----------1-11---221-211122-----------211-11121121111---11----1------------------11----1121------111---------1---------------1--------------11--112------------1------------------1----------------------------------------------------------------------------------------------------21-11111111111111111---121-12112211111-11211111-1-11----------11211--21111111111111114---1---11111-111111-112---1---2-3------111111111311-11-1----1-----1------------------1121111552222212233333222334333235515271122143232123222233111122-11111111-2251113111212122111112211-11111111213--1-------1--------2111--111111111111111111111121111211----211------31111212332222222-32223222323232222244341211-332232333332322312122222--211111111111---1----------1112111--1---------1111111-1-212222132112121211111111111111111111111112211121221111111111111--11--------1--------------1-----1------1111112111-11- 56447652I65225755624455654577676755545152765656455546565655485455565354574454354455554556473547654445544672889LAB86BB98B76A7EA8F9UiC1ABD8768A68E679878C96A9A89C685AC844A55I77774586o35575868A2976467334 * d.131.1.2 DNA polymerase processivity factor
[ 655] ---------------1---------------------------------------------------1 --1-1-------------------------------------1-----------------11----1--2--------------1---1111-------1---1-1--1--------------------1--1-------1111-4113--2--11-1------111131----------------------------1----------------------------------------------------------------------------------------------------------------------------11--11113-11---1----------1--1---------2-----------12222-----1111211------------------11-11-11----1--1----------122--------22---------1121-11-------------------------1-1--32231-----------1111----2------------1---1-1-1-----------1--1--1111111-----11--13-1--1---------22212------113211122222122222222212-21------11---------------------------11--------------------------------------------------351-----------------------------------------------1221----1---------------11111------------112-----1111-----1-------1-----1---------------------------------------------------1------1------------------1 6444866-QB7196B9866B626869A577B89A996696878567797B798868797364536363-48554579378644564754766896B464586458713b3MIKHJMJCCEDEIGLIFPDl*M1SGUC9CEJ6HHADFAB9LCDPCMHDA8JEC9847AFAVBMC71CC9f497C8XCCLBOCA969AAE * a.159.2.1 FF domain
[ 656] --51-332A34B88WF-63-2V6-A8A7E7LU-4-123-----211-1246H61342172614A4-1- 21--1-12---1---1155-54--1154545132222199-19R1121-111111--1--332121C4514----71--1-2-2--341111-1-------------7-----------1111------------7-12----4-23e5RL*j*1111----22Y1CP24-------------68----13G24545568D45533682-2212446bA121F3-11111611111111-11111112112216-21129-Q2115533-3------------------------------------------11---111-5412211111151613B44174N471-5-121733E21--2-111-6--6----11--------111---11--1-------1------2-3111--1-111111111111-1-11-2-----1-211111111311--11-------------------------------1111-11-11977-39-1111--11----1-2-1--1---211------D1----------------------3-1-22---2--1-11--11111112-----1111---------3-2-51-----1----3-1--13-11251--------3------------2N-1-------11--4112333212143-33253224243142222221111-11C1-1211121112222242222334--111111111111---111--------1121--1111---1--541211121112J512222----1-----1----------------------1--411111111111-32----------1--5--1-----------------------------1-54-82846D2-- ----1-1---11--1-21--222---11111--1111111111222111-1-11--111--11--111-1-----1--------1---111121121111211111-11-3221123212-4322-1414C2-44511224123-2121211131-22211111-3---3--1---XL241--U4EIJW1QC1-2-241 * g.72.1.1 SBT domain
[ 657] 111111111111111111111111--------113222-----11132-111121-111212121--- 525-21---------2111-1---2411111--2221242-13-151--322512--2--32-13553422-------3---2111112242-222----2212532121111111---111111112111111232222-11131212222-11112111214111122112121-2-11-221--312--32232322223232224344632323-433233553314124444444444444442243742-33--3-355--5621212456611111111--111111121111111111111111134---333214-58222222232--2---3222212-1--1--------1--424--11312---1-------1241112-12222222221223-11112111281-4223224223641-12-14311222221111111132211231--------------11--------1----1-1-1121112877778566666579767766876456311424413333344542211333313322322-11211-31111221232214122211121121114221111-2331311111111122111122434331314242322222222222222223--1121-1--11197564657669799966-6877989676698877888877444585955555576556555766666663-777677777787123122222111241582333344223223336--------1-6233334644454443554222222222255556566565656----------------24222222----------2----2-11215--111-3--1----141--16111542- -1--123-32----1111122312225-111111211-1--1-111221-12112-222111111--1--1-11------1--1111---1-1-------11--1--2-3642244222--331411113A2-213-1111-1--2----2-12211-2133132---1----2--12-------51-4243--1-1-- * c.80.1.3 mono-SIS domain
[ 658] -----111111111111122222141132131111111111111114211242-11111111111111 212-1---------12222-22--232222214233112-223111---112-2211------11112--2----1111111511122112311--1---2-1121333--------------1221222222122223311124432422321111-1-1111113264------------2113311-133222222222223222122211221322-1----------11111111111111-1---2-11122111113311221-1-11------------------------------------------1----1--112223221-2-1-111----12--414-3221-31213211111--12131171222231735455321221111111-114-3B33658215---221325232-212-1121422111--1111111113331111------------1111116131111--1111-2611---163323474564753466664523C443---631-4111-3131-31324-11--------11341146341345133323-424546224234222551---1---------------2111333--1121112221-----------1----1----4113---111-1---1-2222222222-2222222222222222111233----1121-2-21211----1121222221-1211222222221--21111111324-221---------------------1---43----11---41212----111111111221211111111-1--1111111111111-31111121---1-1111-1111----------------------111111111111-1 33--PJ3-611-44725345442444322222212223222222223337345H124245233--5112--3---111215----13729C7598B-----418-3-13BC7B868254154B5A7366BT7-8571464888A637642732789859-2-6F2C9A9LKCE1-3873743337VUew2Vb76--31- * b.15.1.1 HSP20
[ 659] --1---------------------73332336-----------24-24111----------------1 -121-----------11----1--1-------2222--1--3--62------1-----------1-1211-----------1211111-----------355-111-71----------------1-1-----4-555321112-112222-1-44111-1-2423553--------1----2-------211---------------1---2----1--22-1122221-2--------------------------------------------------------111-111-111------------------------21------------11--------1--11-1-11-1111-1---1----1-56211------3233---7226211111111112-D76A75FB-21----221-3331--2---31-5154321--------1---1G27------------------------------42-2-2---12---2131---222511111--2413141-22185656455D2242B4546A9-------3226EH-522-145-41444-424553533-11-14119342-343312---------GB7271-56467-7124B6667775677546457495---3A57------2-32----------------------------------1-54--1--------------------------11111111111----3-----34338-743----1--------------------3655559749797969657-----1---7233454454441441123334233------F-222122----------1--------------------------12--------6-- ------1---1---35542411332231112-1----11111-22255223796445224441-----------------------1--11151221111331233-3h25HDEBEB9867A98IC6K9RpK1IAO6A67C99987A873B55CA56BD21184421432E1155-564o333DAHBCI3O89A111-H * d.110.3.6 Flavin-binding PAS domain
[ 660] ------------------------------------1------------------------------- ---------------------------------------------------------------------------------1--------1--1--2--11---421-----------------11----112----------4-1-2-1------------------1-----------------------------------------------1------------------------------------------------------------------------11------------------------------------------------------1-1-----1--------------------------------2----------------------11-----1-------------------------------------------------------------------------------------------------------------1------------2------1------1---------------1--------------------------------1-----------1--------------11----1-----1-11-111111-12-1-1--1--------------3---22-----11-21-12--1-12-2--------------27--2113222131-2-A9AA5892-145544422234---------------3-1-----------------------21------2-1--1311---1----------1221-----11111---2-21111------------25--------2---------------------------------------1- 11--LQ2-B435124-212--12-2--341121---------11222-2121111132221212412-131-A441-12-2D953D11-31325562222312764198S*DKFC9I88IB8DDYW6MBf*M3IIN8G79Q9HMH6F6A9LICDCJFELAGGBL8C6HJMK6FC62345h241A2M*n*-*E25FGD88 * c.10.2.6 Leucine rich effector protein YopM
[ 661] 111---11111111111121-1--111----1---------------2------1112112-2-1--- 121-81-43331--12222-23--2722222244452567121242-11211655214--1153434345--------1---2-------12--11----21121-1-4---------1----1--------1--11111----1---1--1----111111----1-1--1111--1111-423-----11333333233233323344222433411-2231344554371222222222222224431532-15811121----3211111-222112434354423232223232666656555664553422223372337F332243382814--32422312--12--111281-3-32231-51---3331-----227232135622134343441433-2242282324--63352358444613111225353452222222222211---12------------1-11-111--11------1381-3443945575433334337532332364969761344341222342428112-311---2--------1-2123----1-------1-1-3-2-111112116-----------1-1211111-------1141--3-2314211111432211131131---1---------4331432655B6BAB77-58567996865B667677596A4444-63656665556566557674444511322222222222---1-----------12733333312212244356545241215133332232223333335-------------133343212231122222112------53--1111---------------1---2-1------2-------1211111----1-1 -1--113-731-----33333332433112222121133312222113222534351222221-1---11----1-----111111---13331211111211-11-13234365853232234741326O5-33B213242263322422316262243411521122311311--11----13-112511221221- * c.124.1.3 CoA transferase beta subunit-like
[ 662] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------3-------------------------------------------------------------------------------------------------------1----------------------------------1-------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1---27W-2-----1---11--------------1-----------1---1-------1------------------------------321-1-3-----1-----r16*mna*pWOKPMPQPjkHoQ**p-*c*MMNPeNVdLGUQOJcKL*UgMSVCMLI9I89fE8U7G3C-1-11151-11--1-----154G3 * g.3.9.1 Growth factor receptor domain
[ 663] 111222111111111111111112311111112121111111111111-11112333232332221-1 2231111111111111111-111111111111111111111111111111111111111111111112111111121111222222222222122211-233323321311111111111111122222222232111111111221111111122111111111111211111111111113323322133444444445444444534333444433243433333332233333333333333333333333322333233333223323233323333222233222322222222333333333333233333333323322444333424222222222222342232122121122222232221124211111111112221111111122222222222-22122121231122222222222221222222222222211111111222121221111111111111122111111111111122112123322222222222222222222222222222211222212112222222222522332222222222221222221332233332211111111222223222222222222222222222222222224322222222222222222222222222221-2222111-11122222223332333233-33333333333333333322222243322222222222222223323222321222222222222111111111333322322222222222222222333333212122333322223222222322221222222333433333432332222122222121211232222221111111111111112-212122111122222222222222222221112 1111432-732133311111111111111-11111111111111111111112111111111211222221123211-1122231211111111-1111111122212A346333352222322392226E2-33332223222-2232122262241222524232223211323765O6654463451345555665 * b.40.4.4 Myf domain
[ 664] --------------------------------1---1------------------------------- ----------------------------------111---------1-----------------2-2--------------11-----111-------------------------------------1----------------11-------------------------------------------------------1------------1------------------------------------------------------------------------------------------------------------1-------------------------------------------------1-----------1------11-----------------------1-----------------------1--------------1---------1------5------------------------------------------1----------1-----1--------1---1---------------1--------1-------------------1-----------------------------------------------1----------------------1--------------------1-1--------------1-------1----------------------------------------------------------------------------1-----------1------111-111--1-1------------------------------------------11----------------------------------------------11------ 3911MI8-B45-78A44A688779868885666776696787766679999ABC588958867567663665466565657666646658B84878987866688D1HEWSRVOWRNFEF9GLHbSCWGy*O-TOgBFECMFFNI9JDEBVE7VELDGF69PDEA96ABCF98H63333V434224BGK9G43467B95 * d.109.1.2 Cofilin-like
[ 665] -------1-------221-----1------111--1-----1-76-4D-2743---1X7-1224---- 288-2--1---------11-1-----11111------------------1----------241----21-------------1-----****-y88---P*JZN*H*P*---------------11-313-11K312211---A---1----22--------2--8112--------------1-2-43---1-----------------2221-------2--------2---------------------------------------------------------------------111--1--1111-------------3---------------------1--2----11---11----------M-3-11---------------------------------------------------------12------------------------11---------------------------------1--------------------1-2222----11111----------1----------------------------2-2---21-------8-2212-11-31KO-1---------------------------2----24-12111112---111-32-1-1------1--------1--1-11993131511-9114149254C431-2321-----------111-2211-3-12-32-2121-----------------------------11----------------11111-1----5------1------------------------11111--111-11---------------221111--------11--------------------------121--32323-1-5 ----114----------------------------------------1---------------1------------------------------1--------11--6-1RNGCDIBA8998AAEG6F5L*I3ECQ8988F7BAD8D9A9B68K8BF5B388235B4R64K42B6-2--1-1---2113-13------- * b.3.2.1 Carboxypeptidase regulatory domain
[ 666] 11----3222232222-12----24--24646-11-1-1-1--34132144441-1----------42 223-432444423256755-57--86545554777746864563122-4---345222--437-4454464-----------21-2-2----2-------4-22323-2----------------------1----11-----4-433333433553333333333535324242224242222222---21333333323233332331222333342111--------2211111111111111122221----------------------------------------------------------------------11-292222222526-3223453221---11-133623--1131111--3--44333-----465452224114344444444444244444544352-5553554554445633234422223335555555512223321------------------------------24332222248468883999966889999768584664-3447333334333433331443221342222112343--112111-11111-424-33461214223113-------------------32-23115164432-22222222342222222432332--13-----2224444-343333333333-3314333333333233333464352234444444444444444533333332-3333333-333322-1---------343552222-2------1--33333242243366666674557555546---------153332222235355--12322111111111--221111----------------------------------------------232- ---11-1--1--22222233222222211111111111111111111232111132442333111121111-1111111111111211135222121111131311--911-------------21-1-27-1-131-1----1--1-1-2-12----2-1--2-2---2-1-4-2434U3334385862344632224 * d.58.36.1 Duplicated SiR/NiR-like domains 1 and 3
[ 667] 111------11----11211-771711724121--22-53734-1A79F5OH1-2212341321--11 11---935DDF78532322-23113722222222223c9G-4-26322354-3322242233-6954-4G3--------2214-1----2---11-------1---111---------1-----12--112-1122551---15-C11511-11--------74124K22------------5642322-158A9B8BC9A4B9BBBA78AAA8CBB253L533444444RO266767777766677523594-1----2---22-1--11----11122212221112222222222221111211222212112211111219338888678394238724343422-52--3B83--9-134112114123211112112241---1144434433333333336-31122232211-7775455665551113-12C41441--11111111-3321-43------------------------------211-22111-----1121333---111-11121----1-----111--513--2----1-13-2232232-----126611112223--1----2--146--1-21551272-21223-1-22122111111-2213113-111-1-1221--11--2--2-2-------11------B2571652224233321-22312231232322222216679B55521211222222222127-1211121-466666656666--1------------439333341--2--1--41122111-235-1211352422312-234----------22222222232411-1-1-11---------11111--1---1-1113-1-------------------------1222122212-11- -2--11------1111---1-------11--------------1--1111-212--112111-1-------121---1---------------2-----------1--911-11112---2-------------------11--------4-1--23--1-21--113----11--1213-1---3-141--21-1--3 * c.92.2.4 TM0189-like
[ 668] ----------------1-------43444632-----1-211-21----------------------- 11--1--4333-1-92222-27--472222225767A6HE12-3--22----423211--433-241111-----------1212---1111-111---22233-14-2111111111122223211-13---13111--112-1B9678846633558855766375965333454353341----1-1--------------------------1-1-1---------22-------------------------------------------1----------------------------------------------13---11111-11-11---------1-22-----12--1--11--1----1133111-----4566B2145235222222221222-32222924125-3222427655776621223642242351111111131113212111111111111111111111111111111369213D89655576672223767E333314C9F9HCC11443B623167847914414122133433331--287-1211211--2-----1-------112131-1---------------------11--33463343526466333335654444444467--1--23111---12122222112211122-1222112212111112114454252433333233233233332411111211-133333333333-1-1-----11214524522241212222122134454213215176565433465664344---------157644444465654--22221-------322-33--------------1-------------------------1-111-1------3 22-1111-F521111311--1111111111111111-211121111111252111-2111111111111111-11121211111111111311113221211111111E382321322212221322318J31324-2113-23113-114-141423321123221223211226786u63454CAKJ2CB4433337 * d.15.4.1 2Fe-2S ferredoxin-related
[ 669] 11-111111111111111111111111----1-------------1--1111111111111-111--1 -12-4-1----------22-22--1-2222211---111112-22111-1111--11---1-21211343-------1--1211-111--11-1111--22---3112-111-1-14336666-11--1-2----12223--1414113----1-------1-2-1321-------------1-21111-1----------------2--111----221-1--11113211-11111111111111---1-11-11111112111111-2-------2221----1------------1111111111111---111----2--111111111-1-11111----11-1235-3--122112111111211-12-----------11111-11212----------------1---122--------------1-1-1-1---1------------1---32--------1-1--------------------------111-1111111111111211111111111111--112--2------21--22---1------1-1-1121-2211111-1---1-11131223211114313----11--1-------------212-----1---21-------1-1-----121122---1212------11-111-1111111111-1111121111111111111121-1---111111131112321--1111111-----------------1-----------411----1-------------1--1--11-22221---211--1-------------1---------1---1221111221------2211--11--------2---------------------------111111111112-- 33--642-722222453863677656544565522433332444456356899833354122131312222222322222233323--1273353921111-1111-AFLvNKMCTEBDCCCGDNFBRB**H3QHWJEDEIFDCEDFEEDG8DQDDDEPIKDAEE52E66418BL1341-11112774975U33A9DD4 * c.50.1.2 Macro domain
[ 670] --1---2-------11-11----2---1------122-21221-1115-2741-1-21-1---1---- -14-2--1111-2-11233-33--243333323343--33--21-2------1--1-1--77--6-A2561-------1---11---111-1-1211--1321-421----------------1-1111122223122--121116216334--1111121-2412314421121-113124----------522222221-1121-12---22113-2-1---------6----------1----1---1---1-----1-1-------------------11--1---------1---------------------------121-----111--1-22-1111--11----1224-1-21-2--3--11--31221-11-12242431-32123------------11123421322-3-1213-234--1----11222221----------1----144---1---------------------1-2-11-1--1---------215553--127777151--11111----3121-2-2---11-----12--111--122--2-43411--222---233221122111-153111--11----------1-------1-112113--31-121-11211111123111211-----1-------1-1--3-11121111---211-1-1-1-211111111---23252----------------11--11-1--543444433444---1121115688-241-----1------1---------------11213-2--1121------1------22121------12221-311111111-----11223344----1--1--------1-1--11---------1-----1-------22-1 2221CF3-4-111-398OALBFBZRXP334333BFE7A7A9AB453NH8MDGHS57KJ8BC9211--11-1-1-111111----1-12-DQD8BJB---1363FJU-4G3G7A3465321112112-227K4--53-1-2222---22--4-15334A521-5934-214-33D26663E3-229GqX*Crb4445112 * c.66.1.12 Plant O-methyltransferase, C-terminal domain
[ 671] 1111121111111111111111121111111111111111111111111111111111111---1111 -1---------------11-11----11111--------2---1------------------1-----------------------------------------1-------------------------------------------------------------------------------------------------------1-11-------------------------------------------------------------------------------------------------------------------------------111---1---------------1------------------------------1---------------------------------------------------------------------------------------------------------1---------------------------------------1-----12-------------------------------2---1-----------------1-4---------------------------------1-----111-1-1---1----11-------1-----------------------------------------------1------------------------------------------------------------------------------1--------------11------------------------------------------------1--------------------------------------------------------- 3333655-722233512223433343433434343334344433333333333323343333343333143433334134333333343222233254433734323352*UabYUSQJIJJRPTVMcPs*T1jUmFJKIWPMUNERFQNLQKcKRIGKBLHCWFSJGHJlKNVB4223G2234243432444433323 * c.52.1.20 XPF/Rad1/Mus81 nuclease
[ 672] ------12111111111111111111111111--1------------1--2221222---11----1- 11-1311311111-12211-122222111113222222112111112--121311-----1111-1-433321222222111122111121211111--1422242313--------------12212221222144432--1423325221321132312222213233223222212233112331--1--11111112-212112-111111211---2--------132--------------21111-1-1--1-112----2----111---111111111111111111111111111111111121111111111-133111112121222221333-111111-1211111111121112-123122222-1111232113211322211111111112-4343323311---11-12-111--2211-111----2123333333312213111---1------2E-111-------------22111133333333333533333334433333333443322333443443333443333223323333333211732213121111-111-2232221211-11-21212112-111111122113112-211-33232222213232222222222223222222---2333------22232222332222222-3222222232332222222223222232222222222222222222222221-222222222222--1311111423422222122-221212232232222222112222222132121111132221111111122222223332222121222223221111112--21133---1-1111-111111---1--11----13---111-32-11---11--3 7353831-6151354211-2211212-542411121111211111-12231132533-22231111-1112----1--31-1111--11-32111--11112--2--341DD5D5CC74527BADO2B2K*E1LFC1752B788738222971J3H94A31125G31852548115552N34347NAGD-H95531-32 * c.1.12.3 Phosphoenolpyruvate carboxylase
[ 673] ------2-----------1-111111121131--53442445321-1253B652-----1-1----1- -2214122---11121111-121113111112226222321423321-111131311111433223432422222333111121-1-13333-3-----23433233-4----------1111258454554486566342234-544444423223233323424445513321223124113-11-----13333423333333324-2211333--1621222222321-222222222222211112121212213--12222222221111224332223-221112122211121222222222222321112223-422222222222222211233332-1-1-1134332---11111-----212432211211443332126345422222222223-332331452521433454333333121225414254221111111111-111335----------311111111111111-----121-2322235555452111133342233224351426-3233-13132112-13512-1-314443444311122152221112213321334312234212242-22111-------11111-1-1-1--122223122152111543421122251223521--21131------3-2--211111111121-1111111121111111111211111111212111111211121211111212-2--22--22222--11111112222223231111111---111112322221221223333333433333333311111111113334121122213211211111121212--1-221133--------------------------------1---1--1-------112 1-11223-7411221342314323512123111223233332241211442254-214245613222331313--12-3242223211221344233132125123-222746216B3111113371126F5-412211131-41-221-4-14221-225524323313A424237C8*7672873222537648348 * e.26.1.3 Acetyl-CoA synthase
[ 674] ------------------------------------------1------------------------- -1--1---------------------------1-----------1-------------------------------------1-------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------111----------------2-----------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------1-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------111--------------------------------1---------------------------- -----1-----------1---------1111-1---1---------1111-1----------------------1--------1-1--1----1-------------111*QVXJbUNMIMMXKukGsP**p4uc*RNNKeIQaGJQPJMaLIkKQIMa686E*Z12211-25Gw------------1112-------- * a.77.1.3 Caspase recruitment domain, CARD
[ 675] 112-1122111111111232321-22221122-1-21332312----3123-121-1111-331--11 14223---11-11111111-11111111111121111111-12311111121222111111-222122233----1--2213242344553527552124334344423111111132233335754766637373221122131434356452334444434334444554435444435411111242333444444543444544332233443222242111111144233333333333333523322------------11----------------------------11---------------1---------36374444444454554444444553231442-33621244213332324235323122222223322222222222222222223-3353333323222332224332222222222222222222222222212222232111222221132222222222222222222121132111122232312222222322222122211112212112311111111121112111111111111111346767234448443265764634711212435422232222232133333334134512222111111221111111111121111221111211111111121112111111111111-11211111111111111112221122122222222222121221111111111211111111111--121111111112111111111111111112122222121111111111111112111111322223222111111111111111111212122111111134444444--------41-------------------1------13333333322112 111-112-313-3131111-111111111111111111111111113121112111111112111111-1111111111111111111113111111112131323-1424432321111-22152141AL5-72812115-2211222133161331222333211223C64323435r6432454581364633335 * c.92.1.2 Cobalt chelatase CbiK
[ 676] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -1----1------------------------1---------------1-------------------------------------2------------------------is*o*iaVLOGScQ**M*T**d8*k*OSLOwQXoRAURJEgLHzQZWdSANI6MHA4D66KAB92------------------------ * g.76.1.1 Hormone receptor domain
[ 677] 11222321111211122112222211111211222343333332322211333335333331112112 3451212111111112211-12112311111132221322143522212221222111113322854232211111111222222321322313221--232334242211111111111111122222212222221222221235445532233111112452233353111211321131121122211122222311121213111111112121111111111112112222221222222111111111111121111111111112211111111111233212221212211111111111111222221222121132222223221221111111212111112222112221221122211333111111111345442113332411111111111-22222222131111112151122242111122222211111111111211113123311111111111111111111-111111211221222233332346333333364444332433344-1335222222226222273333332222222224353143332222332222232222212334334332222222222222322222222232443323222222343333233333333333321-2332311-11133433333333333333-33333233333333333343333374433333333333333334333333321422222222222112222222333352722333333222222332222222222243444443334333333333232132123222333333222331111111111111112612244331311111111111111-11111111111111111-112111111112332 1111111-212121241111232343122111111211111-12221111121211121111121111-12112111111111111111121111131211311121163C364521211211221121182-11221-11122-1111-2111153141221244211211223222192222222341344421124 * d.115.1.1 YrdC-like
[ 678] ------------------------11111-11------------------------------1-1--- 2221111111111111111-1111111111111111111112231222111122212111221211112111111111112122-212444323331--2222222232--------------12222222222211111111111111--111111-1---111111111112111112112222211122233333334344434432443334422231222222221322222222222222232231222211212222211222222222222222222222222222222222222222222222222222222222334222222222231112222332221132211342231222322122211222212222222221122212222222222222-222222223221222222222222122222222222222222222222222222211-11111-122111111111111111111222223323333333333333333333333333333333333333333333333224222132333333312233222213-111211111222222232222222231111111111111111111111111223333332333333333333333333333331-3333311111142333333333333333-33233333333333333333343333333333333333333333333333331333333333333--33333333333333323233333233233323333333333333333343333333333323222222333333333333333333333333333333213-212222111111111-121122---2--------2-------3323333333-1-2 1111231-31111111111111111112211111111111-111111111111111111111111111111111111-1111111111112111111111111111115235B3554243344477263BT5-75B334492355233434459353441492322242351212311272222332251522221112 * d.15.10.1 TGS domain
[ 679] ---1-12111111111-21----1-------------------111-----------------1---- 111-1-1222211122211-12114211111332223222-11232122211322-221112-11-2533-2111222---211-------1--------1-22223-1---------------11111111121---21---3-311211111221112121211111111--11112--121-21--1---222222231222222-1----222-112---1121121--111111111111111111-12-------1-22---1------------4---233----------------------1-2-11--1112---111111221131--111---1111-312-----1------------12-22443-------321211241121111111-111-11111-1-122-3221332222322-322212111143311111111----2111-------1--11-----------------11311------3223232222222312122123232142-122114111-11121423211132-------1111221231121111111-11-11--2----1-22-131111111111-1-------1-11211311331312123111122112212121112----113------22211113333333333-33343233333333333331212111222111-1111-2121-221133331-111111111111--13111111111225-2111-1111211112133433221211-1---4133114434222---------1111111-111112111111111111111--2-333322------------------------------------1-1-------2--1 2221352-A49-3228775455545674434454542745577556755567A76945675753555545664745625654455376536373445342232777-3N58FDCEEA7646485IM5D5P*B2FBF7564F77C727732972D6888856763363E47D77342542G86757758658E9886787 * c.60.1.4 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
[ 680] ---1--1222222235-32331-131111111-111-11111--1---------11111111----11 232261213361128BB66-6C2269656666BCDDACHB153713223111224313--76B22255431-111111-7ZC411-1122222222---1211121212211-111111111111342222231123322---2122-21122222222211-21122431221122211112211111-2212222211212221121222122221213122-1111-111111111111111112111111-311212-21----------------------11-------------------------11---1111382221111111-111132--1-111--12214JF2312112----2-11222222211111537582322324211111111112-43433634342122222222222227332213213312311111111222-222311211111111111111111111111111218A215654343365322222552822221253466872244252133362355113322132-------1223231311-111212332-321341121331324121111-------12111111112-11113332112224254444234445746437541-13123------22551332223232322-2222222222231222223565443313233333333343433211211112-222222222222--2111111----111122221111111-111133223222116233132231145551222111111111133334434433333----------1111221-331121-11------------1---------------1----------1---2112 11----3-421-11123222231334333111143233332332331111237B2111121113211212111111212214433311147332352222211314-1122211132111-12-12-122H1-23211-12121--1-1111-11231113-13111412E32121132N2233232462322154331 * d.168.1.1 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
[ 681] ----1---------1-----------------------------------1-1--------------- --3-------1---------------------------------------------------------1---------------------2-----3--22---1------------------*--------------------------------------------1-------------------------------------------------------1122211--------------------------------11----------------------------------------------1--------------1-----------------------------------------------1----------------------------------------------------1--------------------------------------------------1---------------------------------------------------------4----------------------------------------------------------------------------------------------------2----------------1-----------------------------------------------------1-------------------------------------------------------1--1-----------------------------------------------------------------------------1---------------------------1------------1---------------------------- 11--JFB-795175H245323232542112221-32234322111-14222133123-3433422332142311332-1-33433421-4L446F723216257F4-ISZ*IEJIGAB9E89AATK8JEf*G1LFP6BABGBCKB8ADA6DA7JCC6AC9C62IDB9KEKO5CD64HM7P221R9p***3*i86B8DD7 * c.10.1.3 Cyclin A/CDK2-associated p19, Skp2
[ 682] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1----------------------------------------11------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------1--------------------------------------------------------*ndg*ppTJONSgX*pLsK**c4rh*KRMMZLXoVHYNLGvOHmHoXaeKYP6FSE9RIKJ86A2------------------------ * g.27.1.2 VWC domain
[ 683] ---------111----11------2---2--1----------1---------------------1--- 224-31121111113-111-14114211111352321588121341121111562222--22523252221------------11---11----11----2---4132-11111111111111111------11-34442---4221232233322111121232323331111111211113-311---21144444444244444411211244411222221111112211111111111111111111-----------------------------------------------------------------------2--2111-11111-1-------------------------1-----1--113222------2154532343334---1--1--11-21112-24-51-31122344354444--1132----5-9--------1--1--1-------------------------------------11-1-1121-22221--12222211212211---411---21-12112-------21---------1-2-11121-----------1-111211--1-23------------------------1--12------1-321-----------------1-------1---------1------------------------------------------------------------------------------------1-1-1111--11--------111-1--1--------11----1-3325122122212--------------11-11-------11211-1-------1-112111-----------------------------------------------3-- 2222C53-21--223573665677C472222-2545333323433344347HAGACB31454332222222223322-2223332343336373453332342332-5K6hFH7E6CFAAAABCLM7R7b*D1HERAGCAEC9BA6BBCDB79HBFCAD475AE7A7BC8G77GA3598*77786ABAI2AD6558576 * d.16.1.5 L-aminoacid/polyamine oxidase
[ 684] ---3-21333333332-2--111141143433122-11---1152112325331---112-2211121 -----------------------------------------------------------------------------------------1---------------------------------------------------------------------------1-------------1------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------11--111---1---------------------------1-------------------------1-------------------------------------------------------------------------------------1---------------------1----1--------------------------1111111------------1-1---1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------ 8988DE84N8698988A968988697666786877878888788877797888899888888988878488778888488888888888AC9A98A77798679BG88CEMCNBABBA998CE9GG8T4X*J2FGKB6B7J9ALB99989C8BH6A8AAAHH9BA97F9AH8BHCA889*B9988H8DH8DA788A9AE * a.129.1.2 Group II chaperonin (CCT, TRIC), ATPase domain
[ 685] 11212112111111141111111121112131211111111111111211111111111212111-11 1131211111111121111-1211141111111111112213233221111122321111113141333322111221222151111111121111---2222263213---------------1111111111111131111112222221322211111111232342111----11-1-122111111131111111111231113322141113312111112121331111111111111112112132-111111111111111111111211122111211111111121111111112111112111111111112213222222222214221111231311312275124111221111111232222222223226662222222222332333333-22422423432142233327533343122344333332233333333244322121111111111------1--------11112112123221-2443422111122332221214232233--221112112331431121111---------11411122121111111111121111112211111312-11111111111111121111111-22322-1-21-1-------12------1-------1111------21222122332222222-122222222212222222-22411111213221222232222221------1-111121111222111----------124-1111-111-----12111112121111-333333332133211111111111113--11-----21--111121221111111--12111111--------1--------------------2------11222111123111 -1--531-3211111413262243314442233223332233333324322523222342123442322221434232223334221114431442432333-373-333EALAGDC6576787PE7H7Jn9-C7K5876F679768735876I8D88B33846336C46D6563123-J--122545B222222--23 * c.1.9.6 Hydantoinase (dihydropyrimidinase), catalytic domain
[ 686] ------1111111112--1-111-1A641243------------1-111-21--------------11 1121233455523234455-574446555554766766BA34354-33-11-533343--44524784545--------1-1311-1----1--11----114142311--------------1112111111-133333111223323222223312211223312221112111121121132111-12233333332314333321122233432422221------211222-2212211222------1-------1--1---------------------------------------------------------1-11211111111112-11-11112-1111111---1---211----1--212344112121332234342313211111111112-4524442145321334323321221442122221113222222222252323121-----------------------------242512222113332332222244434433323434444134432343314433223354223222222223212322332-121121--1111111222111217421------------1-------1---1442224332214331111221122231322312-1442211-11122222212222222322-222222222222222222222222222222222222222222222222222212444444244432213222222222312321112222221222232233223442132222212222322211122222222232112111111211222223221222212222122111---------1-1---------------------------------1-3412 21--124-53312454142455564452322224311111121111222233542313433331111111111112222211111111324114212121212343129387C7544443144589473Da8196E3556645664545263255524679337331523442651214R3332263662963542336 * d.157.1.2 Glyoxalase II (hydroxyacylglutathione hydrolase)
[ 687] 11-1121111112111112223221--1---11-1----1----2-1--1---11111111---1--1 111222-222211123322-23223422222343233221121222231212112232--1321321121211111111-1311-11111111123---1111111111---------------1----2-1-1-11133111621-------------------------1----------1211111-111222232232222111111111222222-1-1111111111222222222222221112111111111122111132-1-111---1111---11-----1-----111-11111111111----------1-1111111131112211111-1112111211---2311123212-111122-111-----11222---11111------------11111111121-------11--1-1111-1-11111111---------11--111------------------------------1111-11-113332222222122222222122432223--1111123222--1--14----11---------1222233121-2-22----21223311211312525-1--1111112221111111--221--11-121211111112111122411231132--1-21-------111111111111111-1-1111111111111111111112111111111111111111111111111111-111111111111---1-----111112231---11--2-22---11112111-11312222121211--23533----------111121221111111111111111-------11111111-------3-1------1--11--111----1----1321111111-2-1 3211655-93385465753767666686755555675766666577788887A988A557886445463555656555556777563335967878556533554518PJGFB98B67454575FB4F5Q*A-F8H4765A6776375567637768786697E955754766A83334R1214392247667B74873 * c.31.1.5 Sir2 family of transcriptional regulators
[ 688] --------------------------------------1---1------1------------------ 32311312222313111----2--11-----122221-1--112122211-2212222--1-1-111---1-111---1111111111111212-111-1112111111-2222221-1111111111111111-31111111112222221111122222222111111121-11121-11222-1--143314445344444444433443444344433334334345434443443444443444444125455443335455445514434445554444644555555555554565544453444544555555434433333344444333554544224321343222252-2-3244331-431222222112122-221222111122222223222-2232222221222111214112231-22222112122222222222222222222--12211121--2222222222222212212112233323333334333333444333333343232233333343343433222334544313343233332343211-2122232111222232113343547323-112111111111111121112122223332323332342222332222321223222-3333222122232323322222222222-22222222222222222222222233233333333333333232222222231222222222222112322222222233333333333222222113555455432322111131323133312223333333333234333333233333323333322222222222211222223222432211111-2111112---1-1212112-124321211-11- 11--111-3---11111211111111111111--1-1111111111111111111111111121121111331112322311112111112111111111--132-117221-1----11111111-11131-111111-1-11-111-111-1----1---12111411--111321182112123241512252112 * d.66.1.3 Heat shock protein 15 kD
[ 689] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-----------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------1--------------------------------------------------------------------------- 4323KH81kLR298BAABEA7895A49666767998A868877667BB9ABBBA9BGIBABC7698775576787A85788668677769OBAKPI8686886FEE-K*8PA946855877666IB6C4at9-D8C558795876773457836675668F7987ACDNI754933Zae*PVRLQKHOOCKfJZDGFEH * b.85.7.3 RuBisCo LSMT catalytic domain
[ 690] --1-1-----------21---1-2---------1-1211111111-12215443---1-1--1-2--- --1----------------------1-------1-1---1-------------21-----------1---1-------------11------------------1-----------1-1-----1---1-1----------------1----11--------------1--------------1---11-------------------21--------------------2-1-------------------------------1--14------------------------------------------------------7-222213333-2-22111----11--1---27741---142--11-1---------------U45--476876----------3-1111111-9----2212255222351---3132-132-1--------------11-----------------------------------P****1----1-----------------B****7G211G7ohh*c*4**471-------------1---1--2322111321111-321-1113-1111---2111-------------1-----------------------------------------------------------------1-1-------11--1--1-11-112-------1----------------------------------------1-------------34---1----------1----------3-11-11---2----1--------------------------1--2-1-----------4------------------------------------------------12--1---- --12--1------2---311-----------1---1-1-11112-1-1--211-1-2-1-----2-1-11-1----1-11-------------1--4------1-1--321111721-1211-2--226271-145-231-1--2-1232-121-33-L1---1212--211-31--------1---4W-11---1-1- * e.26.1.2 Carbon monoxide dehydrogenase
[ 691] 2233222222322222-22222241111121133544353543222224344442222223222--22 2321611122111121211-11111111111111112111244321111211211111114511423334211111--111222222211111111-1-121112111212111122111111-111111111311111111131222222222222222222222322312221112122122222---22343434333233433353333343423233111111114311121222221112211111113222211113211222132121-1111111112121111111111111111111111121111-111123212111111121223332111112112133333333332432112112222222221111123111122533222222222224-112112123221234322333245221112142222111111111111111222322222111--11111111111111111111123122222232243332333445522222332A334311222341223213212222222342222222222522123223222432221232232222222211132233233333323222222222322223333322322332222333222222322331-12223------44322323444333443-433444444444433333344433322444422423324444333344442223323333333331222111112222223323322222111122232222211112222222223322222222211111111112323222222222222222221121111112122223311111211-------------------1----1---11111111112111 1111111-521-1121234436246462322122422232222222423563453322222222522213323234425435534221212222312431111221-15124111111--122213111161-113-11111114111-111144111411B1-1111122132111126111-133392311131231 * c.34.1.1 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
[ 692] 2232121111111111232223211--11---11133222222----2---1-122222221111--1 -16-1123333---21122-24--112122211112222211-12122-111222122--442132456541----1121-2-42311-----1-----1111-1---------------------------12-22155---212-221112311111121121-11-41111111121211-11122-221333332123224222121111321222-111-----1121-----------------1-------------------------------------11121111111----------------------121221----1112-21122-121121--21211341212-23111231112223--1-----11345--322212----------1-22222222-2112--111-111--11-2--31-----111111111111112111-----------------------1-1-1-11222-12-1244444442222222133332344745551122412233325331327111111222222211233318412-1-12-111-121111321234384153--1-1---1-3122222232322-331121445-1513222223222222222242---32221--1111111-111111111211-11111111111111111111111112-1111111111111111211111111-111111111111--1211111333422311------1-----------1---1--2133331332112113222-1111-11131-12------1-1122133343332222--211133211-------1---11---1---------1--------1112111222-3-- 1433445-932-33833553353222344434423434443332223456353A3353432354343334436454443335553411244234453334231121-1E4968568863B4566CB3E5R*B1CAB36579766537433642B6667577C77562577B69862536i88654CAJC4H5BD56677 * c.66.1.17 Spermidine synthase
[ 693] ---------------------1----------------1111----1-------111-1--------1 ----1---------111----2--16-----12444-451-321---------1-------------3-1------11-----1----------------12111-2-1-------1------2---------------------1--1---11------------212--1-----1---------------------------------------------------------------------------------1----------------------------------------------------------------------------------111---------1111------1----------1111-----11--1---1--------------1-22-22-2--21-1--2---2------11112-------111111111-------1-----------1------------------1121-------11----------21------1-21-21----12-1--3--22---1----1--------------1---1-1-----------1---1-----41---11--111111----------------22----1211-1212211111121121211--------------111---------------------------------333--22----------1------1---------211111111111----------11---113---------------------4-----2112-22-121114222111-11111-1111-----111111111111111------1--------------------------------------------------------1 ----885-63B-336HCKBMFFGYQXDCB6999A79AA89899888CECIDJJJFEIB777944617415--23831-11344354152KfKC9EFA88873667215n3V411-2----111-13-2-121--1----1------2---3------216481687281211-8-3636P646BDw***J**CCFEFHD * b.82.2.1 Penicillin synthase-like
[ 694] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111111-522-111222122222222222333322133333322312332344122234333333331342343441443444454553432353222232276512116RY*m*TNJGDHMGqwEiO***5*VrQFKCfGLaJIMJIFaGEcFOCI*1-1B231131123331121183111135342B22234442 * d.58.16.1 Poly(A) polymerase, PAP, C-terminal domain
[ 695] ------1----------------------1-------------------------------------- -213F3132231--35411-15--38111113855566B8341-132--222834--3--6532656DLB5-------5---5-----121---------1---1-111-----------------------------1----------11----------------1--------------432-----1365555566625555557655575553453547899A98112333333333333322112296425B22948AA22965395342322224333322444444444444444444444444356221555422-38222222232526--2444-111-2----78121-5--112111-3-1-5332-----113451-11213155555554558-116-1614361-A7755668779A311312553125456--------2331--11-------------------------------122-5ED898888884656677AA666645A8DEFE81166523212444675321111152----------111-42---11--1--2------1111----1---1---1--------------------1143112-115141111-11111111111111------1------54631526665644477-66676327676455565546864511-6356565666566666454345553-333243333344---1-----------445---11----------444441--22-17767456836444-345---------1222122222233221133333333-------122-------------------1---1---------1-1-----23---612-1--- ----1----------1----11----1------1---------------1-1-1--1-1---------------1------11---1----1-1-1-----1-------2-1111------1------------------1---------------1-----1--1----9-----11-7-1----1-2--2--2---1 * d.190.1.2 UTRA domain
[ 696] 2211131---------2111111132233443-----------1----22312-3-11132111--12 323231-211211-22222-44112122222222223243132322123221111211--23322344642----1--111-233122222211111--1221142241--------------111111111131444443333242322232233112--2132222221--1111-11-122322113232555553652565336424432443434632322222222144434434444444344431-11111--1-----11---12111211111111112332223122311111111211111112211111141322222323131211111111221141122233211113311211-1313222221121231444324332422222222222-22222123321122232342423312121334444433311111111-33-212311211111111111111111111111211122221222221222212212211213233133122231112211122221212222232112111111111322112-1--131211--1-3433233243333252212221111111111111111132132244211-1211122222222222223222231--311111111133443333333333333-3333333333333333333333433333333333333333333433333333-4333333333331111111113333211212222322222222222222211111212222222132222132222222222212222222222222222222222221111111-11211111-111111-1----2-11-11111111-111111111112212211512 ----112-4221211332152222122222122333222232212113132123233132123-31311121212211312-111111123232121222-21123-21142655432332231342423F3-3441221422331322122231522133124362511E4432222262223172-G2I51-27771 * c.97.1.1 Cytidine deaminase
[ 697] -----------------------------2--------222221--------1--------------- 226442-------243333-343335323333555533753-2-21224223768222--314651343111111111---25-----2222-3-2---1533534332--------------243134213231---21----445434432233323443343233351441111411212225522-22244444444444444423552244644424122222222424444444444444422222--2-22------------22--11-1-------2---2-2--------------------2--22----------1111111-1---221----2-2-2----11-22-222-222----2-44444-----4252222222223222222222-4-22122122463-522354954444227444455555544111111114222-454------------22221222-2222----44444--11123444433222244934444247353I922422321-222233421132-2-33222222233442622446212224113-22222222-33132222-----1-111-2-2222222-------544323424244444434344445244444---3223------122311-2222222222-2222222222222222222111221122222222222222222211222222-211121111213---344444333441445222212122222221333333211244111112123-2112-221---------44484444444444112-1--111------3-222211----------3----------------22-----------------44-1 1122223-1---12222121333432333333333233233123332222343333333232111111121111111-1121-11112145324442233211321-53333643254121144721229J3-34332242123-223222316156432592523212242371-122G-1-2-2--23325321123 * c.23.12.2 L-alanine dehydrogenase-like
[ 698] --1---1----------------1-22----------------------------1----1---1--- 11215112--2-3-53334-532254333334233344A81212112-11-1232123--56312676453----------13----------1-----111-222211111111111111111-----------1---1---1411-1---112232211321-1111-111111121-1132112---221222223321222322211111223112413211111142111111111111111211112-1-11-----11--11112---1221112-1-1--111121121222111222212221122---1221--1---------1-1-111---------2-------1----1--------1-13222111-1223463231123144444444445-124114354D3-BBC9A7EA99CA642114293334679222222225553--3211--1-------------------------2522-27432B89A8A95554CCB7666635AB952331123355623326376112----4-2112122---3421222-222211222-1-1111---11-131------1------1------------1--4212412-2112211121211113123142--1-22-------31223242222222222-2223222223222222223333222223333333333333333423333331-233333323333---1222221112-2324111-211----211-656552311-2266776652256354122111111111-1111111112212311133332221111--1-22221122222212-----------11-------1--------------------- 11--1-1-21111112141654476644543342434443333445111367A932143111322133131151211-11311232-11221123122211424121172E3232233222243662326H4-4242213332232324424153223457246342834863552431923232435A1344346252 * d.16.1.3 D-aminoacid oxidase-like
[ 699] -----------------------------1-------------1-----1------------------ ------------------------------------------------------------------------------------11----3--2-------21-111----------------------1----------------------1----------11-111-1---1-----------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1-1--------1---1----1--1---------------------11---------------1--1321111112--------1------21-1-----------------------------1--55536akojifSQOQJggohUVVSDR*X*JaPX11GGI77645N8769649212--5512222221116311--1-------------12--1--21-2-11-1-----------1--------21-1--431-22431337777625C67768787699--2-5341--11194224754887577776-46586577666776445576661122289678888898686885654877621443547555454111-----------21112223222111111122212212112-211-1-1--243411------------1668944444978593211-111-----------------11-1-------------------------------1---1--------- ----1---2------211-11---1-----111---11-1111---32111----1--1-112-1111--11---112111111----21--11-----1----1---1131-2-141---1-11--21593--1----1----1-13---1-3--1-4-1--1-1112----211---2-----11-G11---11-1- * f.4.3.1 Porin
[ 700] ------------------------1--2-11----------------1----------------2--- 112-2211222121--111-1---1111111-------2-1-1A-34--231877-------118-242--31113441--------155MB-6-----28-51C4B-2----------------1----1----11112-------------------------3--1-------------4----11-124111111---11-1--62442411--1---13-------I1111111111111111111122--21-22-111--1211113---1111111133322222222222111111111111122211122232--75-------1-161---2122-41---2--------1---11-1--3--51--------2--------------------------1-------1--11-211221--1-2---------------------221-----------------------------------1111-----111111-1111---21111-2-1---------111----------------------1---------------------------1---------7-----------------------------113--6-15-1----1---2221----1---------------1111-13-11---2-2--1--122-1111-1------222331-1----------------2--11111--1----------------------------1111111-----1--1----------15-----1------1-2112111-1111-----11111-------22322333-------1---------------------2----1------1-1-----------1-111-721 ------7-A4-----A6C7DCE4D8DE-1-2--111--1----1115523FLITDCFB56751-11113-1-1--121121-----112113639-131-135-2--3A-9WSQTQRCBCACGEkXBg9**G2ZKm7DABN9EOC6ADA7KA9WDDAEH56A13423-221--41-571----76DIAHDB7-474795 * b.67.2.3 Glycosyl hydrolases family 32 N-terminal domain
[ 701] 22111111122211122243224143353333213221222223322412334211111111221111 3242242222252222222-23222222222223334222224222222111222222--2222222222222223332222233433221222223--3322222324222222222222222222222223324443322231223222133222222222123112112121112121144422221222111111222111131222222212222232322222222233232222233322222332121331-1213311333111--2222222222222222222222222222222222222233222333122321111111111111111111312114113111111221121112311222233222222222222222222222222222222-4434423422222222222222222222222222222222222222222221222111121111111111111111111111I12422222222211121212222221122222111121112211222222222121112131121222222221112122323333232333323232333122234423212222222232222222222223322221111223312322221122221222221--2233222111111111111111111111-11111111111111111111111112111111111111111111111111111111111111111221222222343321211111311122222221212222111112111111111111111111111111112212211111122222221211222111111212222-111111111122-------------------------21222222222222 2211232-622122214511111121222222111221211111223333324232223544211111112111122-221112112223544343222223321212A24322224333413252181IJ6-4151221523331323121153332444212221111111343245S4434385273633552344 * a.96.1.1 Endonuclease III
[ 702] --------------------------------1----------------------------------- ---------------------------------111-------1-1-------------------1---2----------------1----1-------------------------------------1----11---------2--------------------------------------1------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------1--2----------1------1--1-1-----1---------------------------------1--------2------------1---1--1-2----------------------------------------------------------------------1-1-1111111111111-1111111111111111111---11-1-1---------1-1----1111111------------------11111---------11111-111-1111111-111------11-1-----------------------1111-----11111-1------------------------------------------------------------------------ -1--34--G69-FFL2--41433313112211111332321222323251242222433--2-21121-2--1212--1--1-11-2116B1-7135543115B7A-3RE8331-344-54251252625G2123924-144323153214223-6331--112121332---224229JA7776****-**A973481 * d.17.7.1 Putative dsDNA mimic
[ 703] -----------1---------------------------------------1---------------- 3331222222212122222-22112222222122222222222223112111121111113221211222122222221112122343111111111111111111111222222222222222111111111112222222221222122232222222222222222222222222222222111222111111111111121121221111111111211111111111111111111111111211111111111112111111111111111111112121111111111111111111111111111111111111121322222222221122221111221-2111233221322212221211122222211111232223223333222222222222-22222212222122223332223233322222222223222222222222232221111111111111211111212112111112322232333333333333333332333333333222323332332222333333243333233333333233333334444643444441444454444333323242232111111111111111122122443333333343333333443333332443442-2333311211133322332222222222-2222222222222222222333224334333333333333333222222222122222222222211232222233334333333333323332333333333333333333333333333333333111111111333332222233333333333333322223331332233111111112311111---------------------11111211122311 1111232-3-121221122122122212311111111111111111211112111112211211211112111121222111111122312111111111-21312221132444433142222BA283Kl6-82E2332323511213-5138233341132111-111343212122F2222333362762353332 * a.173.1.1 Poly A polymerase C-terminal region-like
[ 704] 221111122111122111211231---2----1-122-11111--1---1--11111---------11 -22-6---1111------------21-----1121253121211-211-23--1-111--122-3-4136-2111522----3--1--2-1--3-----225--3---2-----------------1-222-2-132211-1-5-374189E--22--1---34--5676----11--11-1-1------11-1111113-13-216-121-334-41--55---11-31-21------1---------11111----1-2-1-----1--2----1131111-11--3--325141-21---2111211--111--23-1--142-31441242-13322-1411-4132262-3-5-1----------1-2--5222-----22--1--422141----------2-11319741-2-2---421-13221-11-21462132222--------132--31-------------1133--3---12--------21-12--7144231411112224212213262-1---1222-166-12-1-321-1-23-18B55765-1-122-1--111-2--23-1-1-213-1112-412-3141-1---1-18-33345244-1-1--11-11--13--1--71--111-1-113--1-----1-------22121121221124211-1111211221111-11--1343--22-2211121111121111111111111-4---2-----11--11-----121-114-2--1-1--3112515-211222-2--11--2--3-1146-1-2-3--1-1--1-11---111111-1----2-5111-111-1---1111111------------1--2-22143--111-32-31111-------------- 1211221-411-67532343423425344444444346455564445733332234435343--------2--1-2-111-1----2117662576-1-4131251-1W48BGAGD87854576OH4G4b*F-L8L5454A56D768544654B5835577C46482422K-1621C5FQ88A7CDBAF4I8491222N * c.66.1.26 C5 cytosine-specific DNA methylase, DCM
[ 705] 21-1-11111111111-31111111-----1---1--211111------1332--111----11---1 1323411111111132322-22113422222243333434343552212223222322--55514533452111121112124224333333-211---1215212422--------------1112454224362113255432J53533333553333333333335323222223222233233221233333333333333333335533333333333333333345333333333333333333333-2-22-2---2222223221211111111111111-----------1111111111111111111111143333454565636322883333431333323-44523224345454-12223422233333265458454454544444444445-33423522633-6668963946534432244254534333333333323322533-----------------------------32233234323333233333333355333323234444511223211116321323352322222222222412321242111352443341324224223222234354443322222212111111113223334351232232213862131213212112221-32453------43222232322232322-2223222232242222222225322322222222222222223223222222-3333333333331112111112323224221111211221121113333333332323445435433334234522222222212242222223232332222223222222112144334411111111--2----1---1---1----111-----23223323331412 -------------1---------1-----1111---------------------------------------1----------------------------1---------111---1-1--111--11221-12111--11111-1---1-----111----1---3-----------------1--1----1----- * a.4.5.42 FUR-like
[ 706] ---1------11----2--1-----------1---------1--------11---11--1-------1 11-161-1111-1121111-13111211111122323344-1----11----11111---321-2312333--11--------1121---11---1----21----1--1-------1-----1---------1--2112---1-312-----------------1--1--------1------111----232323332324233232222223231213132------5211111112111111111122----------1--33--------1--21-1----------------------------------------1---1-------1--11---1111-1-----2-321-----11-------3133222-----3-33411-22-22------------23523414--1-122232222132221122111-121511111111123321212--------------11--11--------1--33-1121211113112111133111111112313242--11112-1-111-1-22-12115------------1-1---1-1--111-----11111-1-1-1-8-------111111---------1--1123121-1-1-11111111-1-111-2--1-13---1---------12-11111111111111-111111111111111111112222111111111111111111111111111--133323343222---------1111-3211---------------2222221-111-22321111211222-1-1---------21131111122222--1-1-----1121--21--1122----------1---------------------------2-------3111 3-23654-834132-3233231257341-1-2211233235123135245334C2362343534625435328242224326664712259324121121-1-2531487dPPCFXA9A9F8AAIK5O6m*I-RHF9C84GAFPC7GAD8D879BO98N8776sKe5A572ViB91-343131--M5291723184372 * a.1.1.2 Globins
[ 707] 111-21--11-111--11--1----11-1111111111-1-121-2-11-21121-12-1-12-2--2 1111212122111211111-11111211111-111124211222211111111111112221311122312222222222111222131122-111-1-212113312311111111211111111522212321111551113222321432311111112221132331121111111114113421212322222222222222233221122221134212111212321111111111111111111211123122112222213222112121112111133111222222222222222222222222221222122222222223233222222222223211311112121311232223221216111211121242111212132322222222223-1131122222311112133131212112121211111421111111111311213111111111111111111111111111111122111222112222112332112133332322221111421121112222111112121111112112111211114331112123221111321112422211122131132222432322342142112111111222322111221222242122334212--15211-1111122211122222222222-2322222232222222222111114122212111111232222122222221111112111112211111111122231121111111123134112122212311112222223324232213111133333333121211111121211111212211111111124112211122111112111D111-11111--11111--21---22111313331432 42--271-82221122125111122221111111332111-112114211-2131-21-3511131--23311132325414424532212311251114-31725-59777645533173132A1395FU6-8664241645442241122273625777595A545324582-3373W57435535B37A7864578 * c.66.1.46 YhhF-like
[ 708] 11141112222222211121121111123121323543333335444331222132232232222111 23A141-12231-1-2211-1222321111123121223351123331111-1121241133434353662-11122211122212211121-3---11---21417-7111111111111112142212211-22112411112111211--122223--1-2-121211-11111--11111164221213444444542434443633333444234231122232257333333333333333122231-1-11-1---11--221-1---1-----------------------11111-1111111----------222133332222131222222222311121121541421223311231-1334211212212313221122312233223222233-1-21-1-156--5551545541673211-122222211-11111111-112-2131111111111----11-----1--11111-1632122222222221111111132111112223111111112211223323341212212221111111221211-1523232131323-3534445323233-2-211111-----11-------111211--2243242131132222112222233232332-1121122122234343324444424244-4444434444423444443556443433232333333333323422244431-244434434333---1111112222122133333233111132122221223112242222132321111222211111111122222333332223334222211111111112-----11--------1-111121-11112111111121111111112223222333- 212212--21-1112223443335433444434332244414423253333533233643221111211111111111111222122222722334322316222-122355432621-2122-3225-4G215441-2411234-21214-2121226323173521---23222-222-1213-321434222--1- * c.1.15.1 Endonuclease IV
[ 709] --------------1121------1---------1-------------2------------------- 1141311111111111222-2111412222221313111111112322211111311122112212212212222222112111111213331111---221122121-11111111111111211111111111---22---121112111111112111114111121121111123-1211121111111323231231222112111111212111111121111121222232222222221222221111-11112111121111111111111112221111221111111111111111111111111111111121111111111112-1111111212311112132113121122111112-24211111111111121211111111111111112-221221111111222211111212113111111311112111111111111221111----------11111111111112231-1211211111111111111111111222212211121111111114221312121122221111111111221111221213221243321111222112221155341111112114311111111111121111221221111132222111222212112121-1111111-11111111111111111111-1111111111111111111111111111112111111111121111111111111111111111111111111111121111111111111111111212111121122122112225311121111111111111212211111111111111111111111111111333333111111111-1------------------1-1----1211111111-31- 3243643-7343557433436444434223333435543314343358354353445454656436541543344442253444444447C63464353434265526L48AG88774545354FB383Qf6-95C454375562245428247444576BD54632833289364663e57445DAHI4D7475868A * c.68.1.5 UDP-glucose pyrophosphorylase
[ 710] -------------------------------------------------------------------- ----------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------2---------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------1------------------------------------------------------------------ 32-15B6-41232254334332321233313333331222222222333323333334444422222212222322222222222222223334433332222211-F25TVdYcRLOLMEQbSuoHwK**nAqe*NQDHbOUfIGUOGHdKEmTWUQbAMN6DE75D66C7AI21121913-2223543511223241 * a.29.7.1 Mob1/phocein
[ 711] 222-42-122212224--211-21113135454-3--1-1212-54463-112-111----1111121 3252333333333344433-34114444444444444444345463433222343333224444444333332115222132---3--333252112--2222331121111111111111111122122422-3111232123-B25433311441121115313344111112211211121-32--453222222232222222223222223322232322222322232233322333322322222523234243322344342322222112323343332222422242224444553344444222222222214223333443423253652222225323334323353424244332122221211222222225324334242222222222223-32227432322223322322224225222222223322222222222233223251--1111112221111111112111222212222222222111111111112211111112121232222322212221253313112323222311111242212222312141513332121122222453362452222122222221222222122212111111221111112111111211111111111-1211211111111111111111111111-111111121111111111111111111111111111111111111111111111111111111121122222222222212111112221111-1111111111111123112111131141121111221222222111111111111111121111222332322331111231111111123-----1--------------------24122-----3322 11--211-1---1-11-1111111-11111111221121221221111-1112122111111211111-11111-11-1111111111111--11-211-1111-112-14242333221323253-21AO32334231123243123-251142332616323121342133521--12111-112-111-111322- * c.52.1.24 Exodeoxyribonuclease V beta chain (RecB), C-terminal domain
[ 712] 22--1-5444444446-2244---51133231-----------11-1---2-1--------2321-23 3173822422221247511-161129111112755543982775422221113132312246734477795---------1-622122-------1----2231212-1---------------221324222331221111141656445322211111114614688323212222211243334---1222222222322323231211222322322223------22111111111111111----------------------------------------------------------------------------1211111111111-2111--1-111--2--1122---1--1--------41-6343-1--1337376333324311111111111132223533231-11123152212315123261111141122222222-224222212111111111111111111111111111129Q214554366658936556BB5766673464A4A6312122683434784853444-22211111111122233-121-----------33414331-333373-11111111111111111111111-212211-223114121111111211111121112---1312------1------111-1---11-11111-11111-111111-2-1--111----------------21--1111--11111111111----2-----221242242---------------32133-211112334322151346322121--1-11--111211111111211322323411111112221111111----------1------------------------------1-11112-- 11--111-412-2332243233253333231212232222222222223423233363343411211111112111111111111122225222223223222245-3A5D7A9B732324153922725P41655122344447224-2B1342435645313254915622324452e54444E7D63555431115 * b.33.1.1 Rieske iron-sulfur protein (ISP)
[ 713] -------------------------------------------------------------------- ---------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------1222221222313421------331---1-321---21-----------------------------------------------------------------------------------------------------------13----2----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------------------------------- ----45C-1---A9A4444564347435526457565322223343446445345634756634242312433623232322331263346144676353123854-A-1WSTKXgTHEBCITKxoEqG**j6zbz8LEIcEOTMENGCGkBAyEPMOK56J6DB86UDEG47C7----------51415-1-2----- * b.34.11.4 Ply C-terminal domain-like
[ 714] 221222222222322211111111222222222222222222222222111112111111111112-- 2222232222222232222-22222222222222222222222322222222232322222221321222222222222121122211111111111--1111222-32222222222222222111111111122221111113222113-11221121212112114111111111111111-112211-111111---1111-1121---2--1---1---11111111-1--1-1-21111111--1-111122111111111111111114431111111111111111111111111111112111111111111113-322222222232111113331121211111113122211-111121-111333333335334333333534355555554545-333353334433444444544465343334444444444222222222222222222222222222222222222222222222222223222212222223222222222222222322232222222422222222222223222222222222222222111111111111112121111211112111--1111111111322223223-2211222221221221222222161222222212112-2222222122222222222222222222-22222222222222222222222222222222222222222222222222222222222222222112122222222222222222222222222222222222222221252212322222222742222222222---------2----22222222222222--12222222-----1--1111111-------1------1----------------12-1 1122343-3111222231-1322221222111132221111111111112111111141111111111111111122111112121111*1131122222111111212322212-22211121221328P4152512--121V11111-81-e1A4143484536-212433522211811111412F11121113O1 * b.85.4.1 dUTPase-like
[ 715] ------1211111121--11--1---------------------1--1---1---------211---- 33E-71-1-----1----------11-----1--------1---1-21----111--2-----11--546------11-111111111BD8A38561--39655F5754222222222322224333443234435779911131A47844433552322235348546322222222222233411111112232331221222112113342121121211121122242211111111111111111111---11--1-122--12--1------1111------------------------------2---------342111111111212223322322544621121223323341211A2311E14133411111112321122211111111111112-11212113112-311122223242121241111111121222222222223212211----------1122112121111----1312211111512232111111111111111122211121111111131721121322111111111111111112342312121112111122222232143342821111111111111111111111111111211324222516455543655546456456--21241------11121111111111221-1111111111121111112111111111111111111111111111111111-111111111111--26111111111124221111-111111132122232222222322232222222222222---------11111333332212245253863334555111144222211111111711------523--------4-------26214221221512 ---2-22-11-2dX11454-1226-6111111-2341---1--2133223112224311231---11-----1-------111--1--111-433------1-231-1I4336756564-952454464AUA-975-54556554363544-16554641---122-31-1133-5766Z545357426775C854237 * c.14.1.2 Tail specific protease, catalytic domain
[ 716] ---423211111112-2144424E---1-1-2B4BBAACCDDE695BB57DA8B23-11231214-22 1151111122111113422-2311432222243454456824321121122131211-11225111222311111111-1493-1--1426315112112212222121---------------3424234434312221554211332331221111111111114332-111--11--2-222--4471-----------------2-----------12--------1-----------------------------------------------------------------------------1-------------4886K68688A87956DABA453D2832753939CBD666CAB987532-131222111111333472225665511111111111121411323121123322232233255111131232332111111111222116351111111111111111111111111111111111224346111111122221125221211124556433444332434555556552332221111111222345-YGC94AA58A563-9AAA959B7445412AF3233333333422222222234242662221-11211111111124221212122231-12111------12111212323222322-3223223222232222222212221121111111111111111122222121-111111111111---22222211113221322112112122111222212212334223231111111123111211112111123331111133321343323333233332134332222--------2---------------------------431545555511-1 -------------------------------------------------------------------------------------------------------------11---1--------------111-----1--------------------1------1---------1------------1-------1-- * d.58.1.1 Short-chain ferredoxins
[ 717] 11-1111111111111-111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111122111111111-111----111111111111111--1---111111111111111111111112111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111121111111111311111111111111111111111-11-1111111111-1211----1112111-1111111111111-1112213233-1-112211111---11-------1-1--111111--1--1--1111111--111111-1--121111111111111111111111111111111111-1111-111111121111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111121111111111111111111111111111111111--1111------11111111111111111-111111111111111111111111321111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111211111111111111111111121111111-11111111111111-1--------------------------11111-----1111 2222438-A36398C2211111111111111111111111111111-1111111111113111111111111111211111111111112222222222122366813F5JCEEEGGABFBCC7QOAKB**K-MBMAC7CJDCOGBDE86C8CK7EBBBFH86AB92445E13F72556z44432B6B815B3668777 * d.58.6.1 Nucleoside diphosphate kinase, NDK
[ 718] 555445444444444455566562GDFBHHHF2223322222822322223525455655546633AG 1-1--------------------------------------1------1-1--1----------1--2-----------------------------------------------------------------------------------------------------1---------------------1222222222-2222221-2211222-111----------1--------------------------------------------1----------------------------------------------1-----------------1--------11--122-3---1------1----1--------------1-------------------1------2--1--------1---------------------------1--------------------------------------1------------------------------1------------------------1---------------------1--------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------1-111---- 78469874E3429B856876555565865777758554446456554757646565567878666776466667666666999A888677GB698C98776778A889AAFGDBBCH7866889EB8B6X*F-JGQ4C9AG79958B456B57NAD8CB798C79C5BBBB54B88A98f9A878D9BP6MD547D784 * a.74.1.2 Transcription factor IIB (TFIIB), core domain
[ 719] 113-224543443444322322133332233442421354555444444576532223232-322--- 1122112244313238A44-44334743444432223476-1111311141123622311414124A2211-121--1-3433-1--154531343---121112221---------------22213221321222222111-211111111111111111111-2211111111121111-----111122222221222322122-111222211322221111111-23222222222222221221211--22-1--244--22113221312---2-------------------------------1-111----35532111111111-44---11-423-1221532314432564325331--4-4112---1-32B9922357768----------1-115--537852-61131161114322331-531123337333333332221-333-----------------------------1-16-1265337578683333466434446336585774-2323141223344A911321--2-----------2421781425333233214542353533323142311212111211---------123211-21112-----12111111111114123141---1-2-------23223421111111111-111111111111211111144444122222212222222322231111111--411111111111--1------4333--231222111233331111111-1-11123-6454331121221-1-3-11-1-111111112222211111-----------------1----21--------1---------------11----------33123232121311 11--11--422-1-173422442745622223222223534332324444375A4344353314222213352224323432221312323135311111321121-15-23-22221111121-235-AJ112241222343311-31-211711-2115313311-----14-2222B2334141352241312321 * c.36.1.5 Pyruvate oxidase and decarboxylase Pyr module
[ 720] -1-11222222222113----1-63--1-1-113233432334-12-115111111--133-----11 12113114--2----1-----2--11------21114121-33211---1--111-----212-1364631-11-52-1-341-----6562-2-2---1L121353-31---------------11321-21-112211---4-4445--4-111-------3-24B321----1-------------1211667775573586566311111375211-2--21122222-53523222255522-21337---11-322--211322312211-2612521213111-52414313546645574344415511263632547886589875812GA93----23212293-56A32112123311-211-26111-33-G215241-1-11-3---1--------24522724151-511312666753153162-21---1233333333333141742-------------111--1------2-2111242-554355113345444255-432331-5523356--2132-5219252A132-11211232121--11-4-127-3-125464345-2446111-23316--1-211-1-3-11-----------22112-4643412-215-156232-2-1424-1-11--2-2-5------64482234E96444543184533A9446A6525645647356GJE58442534536654473417557231745565545969--4------1223--914--123-15114314121124313-124222813132442212111----------222-2-223613211211-1---4-2---7-1111-1--------215----------1--------------11---1--11-2-1 2-------------------21-1-1-------11-------------1--------1--------------------------------1------1--------------------1--------2-212----------------1---------1-----121--16--------8------2421----11-1- * a.35.1.2 Phage repressors
[ 721] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------1-1--1-----------11---11--11-----------------------1-----1-------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------24--1-------------------------1------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-1----------1--------------1----------------------------------------- ------W--1---------313431232212332112-2----1-1----223-22532422134431-3742537526522223133311--1-21-1-12-351-J7-*baPfYLIHLLMOJWZHQKv*Z3aMsBKEJLINMGDMIIISDFjJWFJD7CTFGFEASCGc**38-25-511111A88S-55----1-- * c.10.2.5 L domain
[ 722] 11-1-12222122222-3223213322332121111112112211111-----111111111111-11 2321611111111255544-47224544444445666476233223112111333313--444233355321111322-11222222222222222---1311121233111-11111111112344434334332222211-31222322222222221112222525212212222111222111221222222222322222222222222222222211111111-3411111111111111111111---------------------------11-------------------------------1--1------32-11----------1144-11-1-1--21125332341214----2--1232222211111434573422223211111111112-43133334272122222323332313222122222312311111111222-23221121122211111111111111111111122222111113333333222224423222212322323422443222222222433234221332222222222323246333333534441222232222333335262221122221112111111144434113322222232344444243333433334331-12233------33332323334343433-333333333334233333333333332333333333333333332232222213333333333331122222222222223122221111111-222133333222223333233232233232222222222222233334444433333111111111122222221332222-----------------------------------------111-12222 11--321-611-11133231111142122111121123331342221211112111111112112111-2211132212212222211111132161111121312-1222211133121--21231224R1-462---1112---111112121231213121153423923211122X2222242541532252222 * a.7.3.1 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
[ 723] 22111122222222222222222222222222111111111112222222222211111111112222 --3-------------------------------------------------------------------------------------4-36--------------------------------------------------------------------------------------------------1---------------------------------------1-------------------------44---2-----1---------------------211-----1-1----1------------------1-------------4---------1----2-21-1-13---1----------1----------53B3------511111111119------3---1--6--7C-834-9515-----43H-7---555555551----3-----------------------------------1-----2--262-F----11211----91DB-322--331---3337132---1----------------B1--94--2---A--------------2-1331-1-------------------------24---11----1---11-------3-----------3----------------EH6-132F1-D--2123--8F22------1-1--14--1---------------Gp3D664--------------------------------------------------------4-C-2-----4BC3-27Z1-----------*--F-----*--------------------J--------------------------------------------------------- 321244423--2434443344444444444434444443444444444444545234445343232221222322221122323234452534233222222242324427ABEH8G9BABAABNJAOEk*F3JBTAD7DC9BEC89E7AC96GBA8AA68A7448B966566413443244224C335464-136421 * c.52.2.1 tRNA-intron endonuclease catalytic domain-like
[ 724] 111121121111112122323222-----2-1-32-----11134-12-1533-111-112-1-3--- 1-2-8--12241--46444-4411544444436454B8NL-7392311-321764215--65317135672-------1-1641-1234423-411---1122121121------------------1------134433---133664665223333333335226653333333333333312452134-1111111121111111333312111113111122222131-22222212222222232111111111--------11-----1111---------111111111111-------------1--121---112-16333445424322331222614--212--22421-1122---1121111511-111113396712-4236211221222224-44144131542-BAAA66577A8857221236534433332333333222113321111111111--1111111111111-----1531-52114678977822228885443323A4E4D6311223324114155741412211211111111----5413----11-23112-112321111--1-12311-----------1---------111----13-121232-3111-211111111-1-1------1------2332-312222222323-132322232222333233456522211111111111112111141112223--211111111111----------1--11224222--31-----11155545261123123327665447452554---------11--------2-2-14412122111-------2111111--------2---------------------------13-1122222--22 ------1-----11344335342575533222211111211113444335346321233222222111-21-212-----12223321147242543223323111-13-5---31-1---1-1---214A2--26-3111--1--1---------2-1--1-21--1-29--2--344a2224431123-5523325- * b.45.1.2 NADH:FMN oxidoreductase-like
[ 725] -----------------------1-------------------------------------------- ----1----------1122-2---1-22222-11-12-----11---1--------------------------------------------1---------1-2-2-----------------222222242-2--------1-1---------------------12----------------------------------------------------1--------1-----------------------------------------------------------------------------------------------------------------------------1-----------------1-------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------11---------------1---12-7------------------------1-------------------------1----1---1-1-1-1----------------------1-----------1---------------------------1------------------------------------------------------------------21-----------------1111111-----1111211111222-121---------------------111--1--------111----11--------------------------------------------------1--- 2*67867-HA8343D112113731113111211---22112112--32221111-2111212111-21-2--1-1-1---1-1-1111135412555454558AE7-IPqDJVHKONEDBEEDDVKEVDY*O4MISAGCBJCFMF9ECC9FCCNFGHIJ9A9AA867889F6BC41646A54418OLSt1rR9Dv***9 * d.129.3.2 STAR domain
[ 726] ------------------------------------------------------1------------- ------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1-----------------------------------------1----------------------------------------------1----------------------------------111-----------------------------------------------------------------------1---------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------- 5257GCA-A351568667777778868886767978674767776767777786677787777557561686675786797546646474B46456434433589719GCOEICECJEFCFDIFgQCWDt*P4bIiBFHCRGINDCFEDBLBBXBNKHFFFEFJFC8H8DB5AGD5886B745B7CEIP7Q98579877 * d.15.1.2 UBX domain
[ 727] ----1------------11-----3-11--421-1---1-1-1-1-1---2--1-------------- 11619-1123111133222-23112622222235654B5625193531121143421311523131466A11111111-212------231--2--1--1211191124111111111111111-111111111111111111114--211----1----11---3121-------------22222-2113322222222232222333333323224252123333334A222222222222222322233111221211111111111-12111122211111111111111111111111111111111111111111133151111111111121114323131121221755211111111111--1-1433322222647621123211143544534434-437434337632B76656B6683424234365524532511111111111122341111111111111111111111111111112263123325455654555434457556523858323311962223113153812121111512222332112112222112221322231322311111334335132-1111111112-12121211-121234312123241123333313232133311311-11222------12332225665554543-6554444444656665661797213352132322333222223433334521-12222221222211-1-----2222216761111-11111-111133443221211177864775374642354-1112111114338323224433244333322331111111122--111111112111---------------------------21-------2221 -1------------11-1-21212133--------1-------11-113124331-12111111-2111--111111-111-----1--3-1--31212-1-1----16-91121-2---1----12--483-323122221222---11-11-1111-----111-2---11-2-32-V111211134111-12--12 * b.82.1.11 YlbA-like
[ 728] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 64-1-26-6-----------------------------------------------------11----------------------------------------1--9-1*bZRYhbMLJGMSKqoThOx*U2jLzEMJGXIVdNCQNJDYCGwMpVROHq*ESu65C5AWQBrU---311--11---1---------- * g.3.11.4 Merozoite surface protein 1 (MSP-1)
[ 729] 11--1-3122222331-1112-12422423412-111--1---6C2-4-2453----11--322---1 3---I--2332---61122-25--4C2222244666A986-D9I57-11221753--4--312-9-CFEA--111-11--241-1-1-1211-12----1D---i6D12-------------------2------111-----225-1522---111--1--11131221-----1------11122--121799999B5B36BA88A4699889191-19364322222CI2111111211221114--1431512211222775533443231243---1----23------------111111111111-11---11111-1AH2223342151-722113231---11---341------1---2-322-1A774-----66A89--153231----------A-344747385C3-F777B86A9B4765743-3511-31662222222225341-22-----------------------------2243624423599A7C6344449988444443E5A39C6-13493-412A35353-6211113----------2-12142-2112-41111-12---11121--143113-11-2121-1-1--------2---221312113-21-3211113-11111111132-----11------213815-1111111111-111111111111111111176596--11111--1---111111612111111-511111111111---1-----2222-2833---311-----1--18888814--1215735675716566-454-11--11-1----1111-1211--34343432221111---211------------1-1----1------------------------1-----1121 -----2--1--------------------------1-111111------------------------------1----------------2------------------11-----4---11111----591-3131--12--111111-11-41-112----1-1----3--------------1--1-----4---- * a.4.5.69 HxlR-like
[ 730] -----------------------211112131--1--112111211111-1-21-1--1-1------1 114-421655523253122-28--222222216464774723333445533-834131--1341212442222222321-113221112223-211---1423224332--------------132233322233444441113142332221211211122221255321111111111112512222-4323333334333343332333233333434411333333452232323333222323344411231132112112211-1-21-22211111111111111111111111111111111111111111111224212223422121213311113121-1431152112122122222--11-33222-----322222242222212221122225-46146441442-222133344121343-33144423243---------1111533------------------------------121311111374466632221AA955555247574143-26532313243332-4-5212121111111124143412331213-2111--1-1111121222212112---1121211-1-------13112111-12123121-1111122131122212412---2344------11-1-212221211122-22221212122112222211-11111-2121212323111112122123221---------------12---------13531---11------1112322332222341343333433322241121111111111-1142222232222442212211311111-1-221122----------1------------------1--------1-------3322 ----221-2111552223224323243222222332122221222322222232322223332222222222222222222222222323422222222224122213223232243123213244173JQB-6792222332E5-332132572232244212222835623242341H1112662242421354451 * c.44.1.1 Low-molecular-weight phosphotyrosine protein phosphatases
[ 731] 11111111-1-111112112222111112111111111111111111111212111131111111111 1221211111111122222-2211232222222333232222222212111122211111222-222322111111111211111211---1--11--------1-2-111111111111111111-1-11121--1111111-1-1--11-31---11111--11---1-1--111-1-112111111112222222222222222223222222221132122222222222222222222222222222111111111111111111111121111111111111111111111111111111111111111111111121-121111111111-1111111111112111111111111111112111-11----2-11-121111111121111111111111-12112211---1233111-1111122------1-1--11--------1--11-1-11111111111111111111111111111-1-1--2---1111-111111111--1-----121----11---12-111112-1121-112111211111-1-1111-111212111111122211122122222211121111111112-2121222-11--112231122111122322221222222212211-1-11211111122222222221222222-22222222222222222222222222422222222222322222222222221233323343232-111-----1222--1-1----1---------1-------211------1----2111----11111-111-122311111222111133333112----1-11111111---11---11111112-1121111111121111111-1111111111111 5533333-D43533357564454545544644444446566555443344545454445545333354333432644345343333645675775S55452365654354C996867442415464464CY7-95B344534444356225-344866722745654B55535434354P66544G9DC7BG3756775 * a.60.7.1 5' to 3' exonuclease, C-terminal subdomain
[ 732] 11-11123323333331121111111111112111111111112123121222111111111111-22 2232422322222323333-342229333332877732344654322222224323231123424245542222222211114111111111-1------1--11221---------------------------333332112411141111222111111111211221111111111112111121132111111-111111111221111111122211211111122111111111111111211111111221111111112211111111111111111111111111111111111111111111111111111131-11111111112-1111111111--11113115362133411-11--111333122222134551114224133333333335-45244443396266656656668746111344555564611111111411131341111111111-------------------3112311111145545422222443533332345211311111233111124214112141342111111111112211211111-11111-11111111111112211111111111111111111111111111221111211113433322222222223232---1123------12111112221211122-2222211222212222221222111111111111111111111422122222111111111111111-111111222211353111111111-111112222222111418888988798988445511111111131112111111211122333334441111111-111111------------------------------------221221211111-- 1111221-411-12222333563545343333333342322333332224433543344444211111-11111111-1111111111136223343222222353--5235A33541221231212428H4-4252222312321212-322214334133652165253562114416---35C5AA27411212-3 * d.15.9.1 Glutamine synthetase, N-terminal domain
[ 733] 22---16333333337-12-2---62252123---------------1---1-11------1----11 1452211111111131111-151121111112322336342452111111111111111122413222223--------1---22421111--1--211-434262233--------------33-1111--2--23323---25132211211222122233213534211111111211212133---23222222323222222223332332225543221112114221112111111111111111--1--1-2----------1-1------------1------------------------------------------------1----11-----11--2---1------1-----1----2-423351111134765643333443344344344413584393556314443856665983222243555553452222222233322431331223231111111111111111-314111223-155375333343233366487777574575768227664345432636243445434211111113647433-1---11-1-221-514-1222-335333-12111111111111111111131-242222143232333333333323333324532311-53-311111121111111111111111-1111111111111111111111211111111111111111111111----111111111111111112211111121133311---------------11111111113277775657544456222-1111111111115222224333233222222221111222-333233------------------------111---1---------------45-1 -2---32-11-12-42-3-311-2-13113223333-----1212212-11-1-2136-11-71321---222-218-522-11111-2-31-123322223--15-12-9311214512-1229A1726T4-53C21133-3431111-2--1231-4--B-2261612*-19-121-711-2-6--736124223-4 * f.24.1.1 Cytochrome c oxidase subunit I-like
[ 734] ---1--1111111111-1-1-1131--112111121222233122212113321-------121--22 332121-233311122211-13--2311111132222434121111--1112233112--111-1-132211111111--1-111212--111---2---2-1114111---------------2312122212211-11111315142113112211131133213323111111112111211111--211--1-1111-111111113211111-11111111111113-11111111111111-111111111111-1-111122-1-1111111111----11---------------------------111----11-131111111-1---22------2--1111122411---111212---1131111-----123221-12211211111111111-22121121114-1111111111111111212212112241111111122211212-----------------------------422111111-12222222111122231111112222222-122152-1123222123223231311111111-1242-3231232122112-223232234222312111--1-----1----------2122233122122212131222222222211111112----112------11112111111111111-1111111111111111111111111131111111111111111111111111-111111111111-------------43214------------11-22232131111222222223323223222---------41112122221222211111111111111113-331122---------------------------------222-11--1-11111-- 1---546-----12243534333344411111111122222221114334454433322444663232223144443245233443233242343A2231232455-5R6P7988A55235333572A4X*81O9D2433A455343434421B465465AI3B8B3223588H528A5*43465D9CV5748685889 * f.44.1.1 Ammonium transporter
[ 735] 11-1111222222222-111-11-11111-111-111------112111----11-111211121112 1221212111122121111-11111111111111112111232211211111221112222221222222211111112112121111221212331--111211111111111111111111221212111112122111111123121131122212121121342221221112211211123233112233333233333333332443233322121112222222222222222222222232232111111121111111211212222211112111222222222222221111111111111122222222224435333333343443223444433121223211341222322232321221111211221211111111111111111211112-11111111121222222222222211211112222221211111111111122112112222222111111112111112222212112111111111111111111111111111111111111111111111111111121111221111111121111212221121212221222112222223221112111111111222222222222122112211112211111111111111111111112-1212222211132222222221222222-22222222222222222222221212122222222222222221222222222222222222222111122222111111111111221222221122111112111121111112111111112121111111112322222222221111112222222222211112211111111111122221111-111111111111111111133223343331212 1111322-622332411111111111111322211111111111112111122222121111122121211121211-211222111111411231222211112114A586F65666255666BA6C5Kh7186E56669568636675847B8665426A22142425514332233G2223262242362343323 * d.67.1.1 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
[ 736] 222-2-3322222222--1--1-12222--32----1-----------------22422322224--1 222242-----22222222-2222422222222232226422222222-22-4422222222222222222-----------22-1-12233-222----2232222221------1------22222422322222222---3222223332222222222222223322222222222222222223222222222223322222222222222232322322222224122222222222222232222----------------------------1-----11-----------------------------------62--2222423-2--222----2-1-22----2212-2322322212--3-2222222223222222222222222222222222-22222221522-222222232222222222222222222222222222332-222-----11-----1----1-1--11-----23222-222222222222222222222222222222232--22322222222224--22---2222-222222222221213222222222-2222222-2222222---------------------------2222-2-2422222222222222223223223--22222------22222222222222242-22232222222222222222232222222222-2232222223222222222-533233333333---222222222222223----------------------2224444444543246543322222222222-2222-222222232222222222222222-2-333333--------2-2-------------------------32222222222222 ----423-736-22253532432222234223222222232234224333224455453242222-43-45332323-3224432422424233242423323322-21583522422613333484619M4-4442323335233433173253735634D54232725555532223b22332A89B3891656423 * c.67.1.7 Glycine dehydrogenase subunits (GDC-P)
[ 737] --1111-1---------------32112-13-59122346434FGA7632G9B--1---121----12 -221A22333311231133-33--3433333334448344-45723232323443112--343-4467775-222---41551-1---1121-1--2---6-2324214--------------2232451-1614----24524152222232222112121111321511111111111112-211--11-22232323222422222221112233-4851322223-1313332333333333311113324233222-3AB551124341111122231113663333333333311111111111114113311115-63BI7769B8B281287711318151-266117742-22362---2-211112335-11--1124543532133----------5-47557844573-7331764887552222-1272222111222222222------1------------------------------1-26-544355555554222177432222-24443334--322-35327543626411212111111111132-13469334242552231544522244-11124341--1-1---1-----------1---22---22222421111114-211111123132--121--------2212-322222222222-22222222222222222223331-211221112111111111122212321--2111111-121----1-1---1111-23121111-2--------132223121131244442443554431213--1-1111--111111111212--643222222311-1---6221121--------3-1-----------11-----11-------11-1----13-1 ----11--3-11-4--23214244332----1-211-212112---312422241123--1--1-1-1-2--1--121111------1122-2---12121111-2--A-2-1-1-1--1------1--11--1-1-21---1---1------2-1-111111-11---111-11---------1135711222431-5 * c.23.5.4 NADPH-dependent FMN reductase
[ 738] 1----211------1-----------------212-1------1-----11112-1----1-----2- 3423422212222141133-321122323321222214463235312231224441222243423346353222222221113223232223241121-33333434332222222222222224333333334342233---333333333333322223333344344222111222121112332222222222222222222222222222222332222222222223223232222222222222222322322222332222222223222222232322222222222222222222222222222222222234222222222222223233322222322222323321223222222222212-222312112222232222222222222222222-221222222321311233233322122211122322222222222222222231222-1------222122221222222111113412243332222233233332243333333222333222442232332332422333333333343333333333333331112121111223222222334334232121111111112111112112222223334333233333333332333333233332-2323212-22233333333333333333-33333333333333333333333333433323333333333233333333332333333333333122211111222332421333333333333333333333333332333332323332333333232233323333333333333333322322222322211523344332223222221--------------------------23133222222223 -------------111---1---2131------11--------11221-1---111--------1----1--1-2----------------1--12-1--1------1311------------------1----------------------------2111-211---13--31---13-----2--1--7--2---- * c.5.1.1 MurCD N-terminal domain
[ 739] --------------1--1---1--11211111--1--------11-11----1------1----1--- 312-11-11111--1---------------------1242---1-111----111111----1---111---------1-11111111111111112--211211121111111111111111322111111111----1---1-853322222342222222223222222222222222222222---1111111111111111112111111111111111511111111222322222222221111111111111112111111111111222111111111111111111111111111111111111111111111111111121112111111111211111121-11---1111111111-11-12111111111111122111121111111111112-11112111131-11111111111111111111111121111111111111-1112--------11--1------------2---11212122222222232222222222222223222222222534222222444223222222222222222222222211122222223322111111111111122-11111111111111111111111211212221221122211111111211112111112-1111-21122224222222222222222-2222222222222222222222224222222222222222222222222222-222222222222--2112112111111322222222222122222111112111212111111111111221113222222221233222222232221111112111111122-2112211--------121----1-11111211111111111111111111111-111 45238A31D2425553254433534333333435643444334354333353333343333345334413534453424343445356545324445334345AAC1389B8645594344444G9476Gg63A5633334434734636443748A4435245976545752653644R444547438644578B842 * b.40.4.16 RNB domain-like
[ 740] -------1----------------1------1-----------12-11--34------11-111---2 1--11---111-1-1-111-11--1311111111-1112112---2-1--1-21-111---1--2123-21-----------1--11------111---1112-311211------1111111121111121211---2211-3-133433322--11212113-233232---11112211--------231222222222222222211112222-1-11112222223111111111--1111111111-------11-1--11-----11--11111-----11-2212-11222-------------------------121------------11----112--1--1113--1---12---1111-32111311122214331112222122222222222-12112211632221122242243322232111121111---------2---21-21122111121--222112122122111111-1--12221121122211111112222221211122231-22214212224354444224443111----323322-2211---1-2---11221--311--1-17--11-11------111--1211211-311111111112122111112211211221122--11123------11211111111111111-11111111111111111111111211111111111111111111111111111111111111111111211111111111111111-1-21122111111111111111111111422111111111211111111312122222211121232-1--222-111111-11---------------------------------------------1-11--212 ----131-31--123CBGDHECDREMDGDGIHHECBIGEHGHGCEDGEFJjp**DHJNGMNR2-1----1--211---------2-113543B-12-312111214-1333131--2-1-----1-11-251-1-1----1-11----1-11-1-12--1--21614222-1-221232l641226-18A312234222 * c.66.1.49 BC2162-like
[ 741] 111----11111112--4------1--2-4--------------------321----2-1-------- 96C-A--1----------------------------1122---A584-154-143--1-----45247B224333211--11---1--JHiV-G33---5J-54T-9-O------------------------2-233761--2-1--2----------------1-11-------------321336411---------1--1---11111-----1-1----------3R---------------1--1212211-12-121111221211111-11112222---111-112---11111111211111-111111112A11-2-------1--612214528-11--231-45--1-4---12-8-----7434-----------------------------1---1----23---5334554785121-1----------1------------------------------------------------511-1----212222211112221222222322-224-----221--11121-11--2-1-----------1------11----1------11------112132------1--------------------1-2-32-8--8-11-1-1--1----1-12-1--------------12221113333333333-2323333344233343331223223--12-1-2-11--1-11121112223--111111111111---------------2-2111122------11---1--------6------1--------------------1333122322314411665665532222---2EF2264--------1-----------------------------11-43547-L51 ----228-1----12AAE7HBB5ICFD333333333322232212263BEGGNOEDD88766-22-11-1--2-3------11111--2264A3522231291--1-1H39467563323324269475Ho6-68D12324225623321422B363242164974562178361-1915111269AFL8I43331135 * b.18.1.5 beta-Galactosidase/glucuronidase, N-terminal domain
[ 742] 221-11-1-------------1-21222-11111111111111112121122111211111------- 23424---------21111-11--2311111212221221-454-11--1113221-1--32--2-3434----------1-1--1--1111-1------2-1231131--------------------------111-----2-1-1-111--1111121211-41111121111121111-------1---11111-1----1-1--3332---1-1-1---222321-----------------11-1-1-3----1---11----------1-1-------------------------------------------------3333333-312---1111131----------1-------------3-1---2---1---11111-11111-1-11-11-1----1--1---3--3---1121121311-22-1--1--21111111111111111-------11----1------------------1----11---111111-------11------113-1-2-1----11-------2--1-1-1---------------13211--11-11121-1-1111-1111-3311---------------------------22-11-111111211111311121131214---2-----------112132222222222-222222222222222222211122234--------1-------22122222--122222222222---3-1-1-----1-3211111-111111111-2222211---------31---11111-1-222112212-42232434442243---------------11---------------1---------1---------------------------1-1- --12683-311-23446555567B8CA55545675756754665556657A8985654456623311112-2223-12112444431--374655533354244731466sBF8ACH7576889HG7I8i*B1ICD5877D67E667776977E7998A6EL9DBFEGCGS7FG72331B22345AECF4AD2452543 * c.67.1.6 Pyridoxal-dependent decarboxylase
[ 743] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------1---1-----------------------------------------------------------------------------------1--*s*WY*cM99EPcFtiAcR**j2cc*6G9CnOMbH4QBA9f88*Fjb**Yja5X74C4DG8DK64------------------------ * g.22.1.2 BSTI
[ 744] ---------------------------------1---------11-11--111--------------- 323-2---------11211-11--1211111121111111-1111---------------212-1111111-----------111111111111111111111221111111111111111111---------2-53466---411111111111111111111122221111111111111233221111111111111111111111111111111111111------11------------------1-----------------------------------------------------------------------1112311111111111111111111111111111111111-111111111311222422222333342222222222222222222-23222232222222222222222322222222222222222222222222212221111111111111111111111111111122232223322222222222222232222222222222222222222222333222223111111111111222122435332222222222444233352333336221111111111111111111111111333332312222233333332333333223231-1222211111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111112211111111122322111111111111111111111111132333333333333333331111121112111422222222222222222222111111312222222222222211111111--11--11---11111-11111-1111121-1-1 11--112-41--43433223333332322222233433333332222223333333232322211111111111111-1111111122221232221112243659-493AB88AD9547336AA93C7M*81B7G65448698557544955B58A785D655654655J3375388Ah87754B6AB2E88764445 * b.122.1.10 LON domain-like
[ 745] 11213112111111112111-1121221-3-53231112111232-3432211211111112221-11 -27--------21---111-1-112-1111121---12---121---11---2-------2-----211--1111111--1--1-111---1-----11433331--211111111--11111----11---1--32322---2-12-23311-22--12-121--22211111111-1111-----2-2--1------1----------1111--1----3-123333211143333323344433333332223223333322332113322232233323333332222222222133333333333333332223333-12211111111-1---33121---1-11--1122111--1-1----1-1--1111111111111111---------11-1----2-11-111-1122112221211112112-211111211123---------111-2-11111111111111111111111111-1--111-1121113223332222222232222222222233311111122113332212211--1512232222---33-412-1-1-11111112-21-121-534552--------------------------1--1116113-512111112112222-2-1221111---111111123211212222222222-222232222222222222232313311222212222222222212221122--2222222222221112444443333112-2---1111---1-111------12213-11112342222422322------1--343333233233333221121122211112111----1133333333--21--1--1--------------------1----------2 3322432-633355331213553777733122234123332334442333344D5332253435523313435345425434443421317212123333342454166D79856697342554C63B3Dn5177D5144A254545325514B2644647G33341631636562341812222E69I2A44563355 * d.179.1.1 Substrate-binding domain of HMG-CoA reductase
[ 746] ------------------------------------------------1------------------- 1112222222222222222-22222222222223332222211122222222222222222222223232211112222222122112323222222-2222222222223333332222222222222222222111111111111111111111211111111122211111111111112221111212222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211122222222222212222222221112331111111121111111122212222222222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211112212113212111211122111112112223222222222222222222222222222322222222222222222222222222-2222222222222222222222222-22-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222223222222222222222222222222222222222222222222222222222222222221111112222222222222222-222222222222222322211122121111122 32--222-5111123--1-----------1-------------------1-11---2---1-------------------------222352-2123231--3214-266425222-2241332A3294EY4-C5612223-2312221242222--2322123232222232223463j34443B474-582442133 * d.43.1.1 Elongation factor Ts (EF-Ts), dimerisation domain
[ 747] ------------------------22222222-------------2------2--2-222------22 2222222222222222222-222222222222222222222222222322222222222222222222222----2-----22222222222-222---222222222222222222222222222222222222222-222222224222222222222222222222222222222222222222---2222222222222222222222322222222222------2222222222222222222222--2----2---2-22----222-222222-------22222222222-----------------------22-22222222222222222222-222--2222222222422222-2-22222-22222222222222222222222222222222222222242222232222222222222222222222222222222222222222222222222222---------------222222222222222444444222222222222222422222223222222222222222222222422222222222222222222222222222222222222222222222222222222222222222222222224442222224444444444444444444442-2222222-22222222222222222222-2222222222222222222222224422222222222222222222222222222222222222222222222222224242222222222222222222222222222222222222244442222222222222244442222244444222222222222222222222222------------------------------------22-222-2222222 ------2-----222322222222322222222222122212222223222234-222-21222222222242222222222222222224222222222222322-23-46338323333232643739N6-4372111223531332-221642344121--11---------222382222223-62222222222 * b.43.4.3 Riboflavin synthase
[ 748] -------------------------------------------------------------------- ----------------------------------------------------------11---------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------2-21-11---1-1-21--1-12221-2--11-1-----1--3--1112-1111-----------1----11111---------1211211---1--------4-gPYeTTWUOIJTcT*vP*S***1*g*PSQImSPZXITSIJXIGPGOLWcLPH5GC95C6AD6LI---------------22---1-211 * g.7.1.3 Extracellular domain of cell surface receptors
[ 749] -------11---111-1------1--------12----21121----1----------1-----1--- 211-3211223-1-HED77-7I22HC776767EFGFCCLC-2-241------1--2-1--212-54246221111---11-1-------1-1-------22---3-331---------------1--1--1----11132---3-2212112--11111-1--2----411-12111112-111411-----1--------------112------1-1-11--2--11---122222212222222-332122-2--11212-1331-1121211211111-----------------111111111-111-33---233---11-1111111-111-11----4-----111-212------1---------14565------2921---22322----------1-112-2211-48-1323--1-1112--1511-11121--1111111111--1---------------------------------11931-1231-2124223211222211111-17151623-121119-1--121--1---1---------------1-----2-2-1-1----111----1---1-22---1-1-1--11-----------------21--1---111------1-----11111----1---1------1-1---21--11--------1-2-1------1-111---1--21----1-1-11--1111-1-----------------------------------7----11111---------6635623111--2112--1243---31121----11---1-1-----------1-11111-----------33--22----------1----------------15-------11---1-11112-1 ----111-21--112NFLDG69AQFPM45534554546654876437B5ECNZQ99A684467121---11-1-2------43361---8E4F23333432-6313--J4O89765E55674A7FA7C4EX5-97866577568684373756D753AA5BM18412214444442221N211323546CC3-22-113 * c.4.1.3 UDP-galactopyranose mutase, N-terminal domain
[ 750] -------11---111-12------------------------1------1-----1----2------- --------------32211-1---411111133111-122-------------------------1-2----111------1-----------1----------1-----111-111------1---------------1-----1-1--------------------1---------------------------------11---1---------------1-------1---1-1--1-----------1------------11--------------------------------1111111111111-------------1-------------11-------------------1-----------11-----1-----11------------1---1-11----1--1------1------------------1-----1-------------11-------1111-------------------------------1223111--------------11--11--------------1---------------------11----------------1-1-11--------1---1----------------------2------1---------1-------------------1---------1------11--1--------1-1---1----------------------------------1-----------------1-1-------------------------------------------1-------1-----1---------------------------1-------------------------------------------------------------1---1-------- --22868-B74177757555786585533243333567786652136545788976A333353212542121121336432432122425647A372223117788-815TTSRTSQFDFBGOHZYBfE**S3ZOkCFCBNDIRJCIBFBPCBYIOJHJ8EIID9A7C8ABAFBB1341613-11FAGB5C81443312 * a.238.1.2 Arfaptin, Rac-binding fragment
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c.1.22.2 Cobalamin-independent methionine synthase
[ 752] -------------------------------------------------------------------- ------11111-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----7641----12611532444331422112211122111222222245543E27432222123111-32132322-2244432143446213332212222EAC1511GacZdVPFGDBKQDucAcJ**X-WUcCHDEZCMXLBKGFENFBgIOLHOCFDB7AD6LB9FAICA1553B--245Lhf*4*D4637461 * a.37.1.1 A DNA-binding domain in eukaryotic transcription factors
[ 753] --------4444444312-----------4--1-----------1-----------1-1-1-111--- 66A-D--1---111-2233-32114233333132221221-114454212--244112--32128146722-1111------3-----HFaK-L44---7L-14M-D-K---------------321422222-323354---2--222111--1112111111123341-21----2--1------43-12-------12-12---21111-111------12333333-E--------------------412-11-1111661111-1133-323---11111--33322223333--------------11111111-42-2111111111119211112-C131--24----1-1-8---3345---2-4233111111-111-21-1---111111111111-32131211-11-211333253322--1----111-1---111111111----------11--------------------------2-1------456331-2222----4433-2413------------1--11-1111-1--1---311111-11--1------1----------1---1--1111151----1------------------------11--34-6--6---1---114-3-12111---1-1-1------11--2-1111111111-11111-111111-11111-12----11-1--------------1---1111--111111111111-------------2----111-----------1-----------31111-1---1-11--------------1113111117231155A9A877752222----22--------1-----3--------1-11----2---11----13-11-112-F21 ----425-422--1-F9E8GEF7IHKE1122228554222311244HEGFB9BHCCC87653313322-22143111111122232---8E696A82221364-1--3178545662443343356275Fc61A9B233353433333133213273343594952135C-1-A2---1------74B9G75-142324 * a.102.1.4 Glycosyltransferase family 36 C-terminal domain
[ 754] --1------------111---11-111111-1--1-----------1-----11----------1-13 2462511111111134433-333343333334344432432434321122212321-1114421325345211111111111412222221113221--1212132131-------1--1111-111-1-1213-333334343331473332233222231243445343212-23312222211122-413222222222222222113333223122-2121--1--45211111111111111111-1111111111111111111111221111111111211----------11111111111111-1111111112113111111111113133211121211211212232212-3222221-1215233632222446465325555333333333333-5535543436415333663644333323232233331233333333323333643111111111111111111111111111111212222222234454434333444544444455444222233343342344342314232223111111121236312112122231222125244223244247625112-11-----1111111111111-11112112222-21121111223221212323--13233------11111111111111211-1111111111111111111111111111111111111111111111111121-111111111111--11-----222232312111212211111221222221221221111111-2221222222---------1111-111111-11133222222221111--221122221111111-232-------------------------1111-1-1112311 1---121--1--112123211211112111112122222222222221211122112131111-2--------1---------1-11--11121-3------11-1--9154654E244-3353541549O5-228122245533-3313222626466312241434222321-2544j23352774A5754454235 * b.47.1.4 Viral cysteine protease of trypsin fold
[ 755] ------------------------2--22-21------11----3----11-11-------------- -32-B11322211121122-241136222223566687A9-6176D442121B97224--7661627575-21112111-1-1-----442311112--1422157A1411111111111111-------------5621---6-6--3111-1111111-11211112-11-11111-1-1112------12222222421222222121122222121332322222223222222222222222223132121111111122111121211121211121112111111111111111111111111112322222112--12111112121211-2211112-221131--11-------------111-2122211111232431213222322222222223-33647334492144528757754712221-31222223122222222-111321-----1-------1111-12---11-1-11-11411122214334232222233423333235343444113322332142322211213122111111111111543-1-3---1------212-1311-445656-11----------1211111111-1-1--2222221122212121113111221221131-1231311-11121111211231111111-211121111121211111142221123111111111113111211111111211111111111112211111111321123232221111222221112233422121213333432332322122211212111112333111212232211111111111111111155--11--------1-111111------21---1-1211222111111-111-413 1111112-411-12212212432625422222332233132323334222314544234211131122112111111111111111223352223322322123423221953442321111215514-EX32A571-2-6-143112216143223233-146442612623621331N3241132383534646244 * c.71.1.1 Dihydrofolate reductases
[ 756] --1---1-7224--27--------24431193------------------2KE-----1-1-12---- 344------------1-----2--1------11-----21--38-------------2------1-12--2----2-----3-----1--------8---6-1--B12----------------3-86K72-6-6F2244---1-55F-C8DH1--------1-C-4B25-5-----6-----19----1--------51-----11248-------831-23-------3----1--1-22---22-432-1------A--1--JJ---3-----------22--212-----1--1----------1----44322222-4D11------2--3-A422-3-E-82-3-2--443E146-22--112-23--A111---------231---4112-----------------1---4--------4------------1------2--------1------1-------------C--7--B---------------122111111111111111221211111111111-11111112113111111421--3-12123311--9--4I351331-2-----463116JA69847-8-1-----------4-71-----5-1-A---1-32A31797A2633A-93662-H8444L--371-7------11--4--132K121311-111-283334327111111-111-28F7--811--4-1S7S811--32111--3*rm5***uF2E-----2-221512114-4111122-12-2324--------11-2-1-2231-42233212332----4-------S47457-----5511312111------2---111----1--1------------------------------2-3-313-2-421 ------1----------1-1-1-------1-11-----------11----------------1----------1---1--1---------------------------2111--------1---24-1-151-1111-111--1-1----2--1--11---3--------2----1------------1--1--1--1- * d.58.57.1 Transposase IS200-like
[ 757] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------- 13--224-72315578655476786786697787776444434653687754744444453244745545524564412443344376659764465555156AHE-481OSfWZVPGDBHFJDihDXE**R3dOzBFEGNGJPIDJFDDN58bFOJHKAB9CC8B7D56L7D892346C31243H7764842347873 * a.39.1.6 Eps15 homology domain (EH domain)
[ 758] --2-11-----------1111111----1----------------11111111-2424451-112--- --3--11122223244255-5322225355541131687621-1-12-111-32233211--1-1-3323111112221-11-1--1----1-111--------2------------1------1322-1-121-222112211-2--------22-----------1-1------------111--1111---------1-------1---------1--------1--1---------------------2-----------------------------------------------------------------------1153333322434-1321--11-111-312133113-1-12-23-1--1--2112--1--2-134---3212311112121111-11111112232-233522221222-121222112114333333333312221312------------11---11-11111----121221-1---4333441111133242222-2432111---11---111211311--311--32-------1--3---5812-232-2112121221234212121211---2----------------1112-2232133-3241-2232223622223233255---1332------32523315555555555-555554555555555555333333222333333333332323323233334--233333333333---111111111112222-----------1---33333232212164553323244432342---------11224222222224422222222221111--22221122--------21-------------1------------2121111111---- -2--134-7231--1441214414645222----21-6353452323319387954544242221-1-12-2112-1111111121122-514564----321312-383J4584884A5644787643Is6-89D45345568744975464A777736496438243432353-74-F-1113BEEO3EA236b362 * c.3.1.1 C-terminal domain of adrenodoxin reductase-like
[ 759] --1-------------1-------2112-11------------11111-----1121----------- 3242242233312212311-12113311111323332122111245612333456221221132243453111111113131-2111111111222---12212121-211222211112222211222122143111--1121-1-2---1----1--112-311--11111111111121-11112211213333333313333342122113332321-1354454612344343333344433433332---221-2-1----22-----1-313253433544444444444445555555555555333---533523265222122222232222422432413323112321-32243212124123111111-11112211111211322332332332-1111111-13-1111222333222112111213222222111111111122-2131111111111111111-1111111122112122221---1-------1111----1111---------1-11-21111212112-1-1-21111111111-11--22111411212111115242213432222411211112111121111111111122221122822221-2232322111132111112111-11----1----43534524446445434-454545455444545455646554213333233244342322424323314324555455555451-1----------111231114151121--232111111---12211111222-11111223111111111-1113222221314411222222222222--2133111111111121212----1-111112211121121122212122232123223 *-11----5211--1234223233232331111212122222252411111-31121212221-3-1-12121-1131112111-22121-13-2-2121112112-22231123-13122-21341516C2-323-21-4112112--1221111-1-2491311--1--11223---1---2-11142331232231 * c.121.1.1 Ribose/Galactose isomerase RpiB/AlsB
[ 760] -----------------------------121---1--1----1--12-411--1121112-----2- 122-3E344451-134512-1311231111112BEA4L442I561732-111687-12--112-2123421-111-2---2-1-1---1-----------1-1-1-13----------------111112211112222112271AC7384A331111111132818E4A1111111111111121122211-13122-41-185-14---1---111213-21----1-21---1111-1111------2-11-1----111--11-1-31---1-1-----11--------2------1111--11-11-----------22-1------2114-11221-------11-1--1------2---------2111221-----211221111211111111111111-12213511211-1111111121111112111321311111111111111111111-----------------------------11111-----5---1--2----11-1-1----12----211-22241123772311-12-1------------211-12122111-1-----333121213CAPH26-2----1-------------------1411--2122-111-333312131221121111---2122------1-1216-2861242422-521133412262311111334111-121212223122231222221121121-111111111211--P-11111---1225-----11------111----1---11-3-121-11321-2133111----------11111-11---1--11212111111111--1-112222--------1-----------------------------3-------14-- ----232-2--23131-32142123-31112121-11111-111111333132221313211--21-12--2--2-----211-12111131-2-334114-1221-69448B8AC68461485SG5E5Y*E-DBG2584A879427354813F86485669E4492645D59712443733242OEKK3ND222C376 * d.4.1.5 Recombination endonuclease VII, N-terminal domain
[ 761] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------1----------------------------------------------------------------------------------1FVRMwNbWLHPTTW*sOyR**m9vZ*JNPLaPasfEZPJF*EIwNkMWa7Jr-7999---p--6--------------1---------- * g.23.1.1 TB module/8-cys domain
[ 762] 1111--32222221311-31222-12223352-11----------11133122-21122111-1---1 3331322222332123333-33334233333432221232213312311222213331111123222222-33333332112211--11121-1221---312-4--11222222211123331211222-121-83335---3265325662222332222443555432223333222332332211213133333243333333313331333323413311111112421111111111111-111111211231111122113411111-1112443434233333333333331111111111111333111223232124111111131332222212-13332231122212222113323221222-11-----111-1121111--21111111111----1--------1-11-121-21----111---1-11--1--------1---111111-----------------------111---1----111-------------------------2111-1111211---111-121-2--121--1----222-122231113212-3221111211111321213-2--1----------------1----111124-21-132321-1-11211----33-22--12--311-11111123111111211111-1111111211111111111111111111211111111111111112111111-221212112112-12-111112323321-122222212222221222232-1--11211111111111111111------1--13222333334323311-1-11---22-1-11233-1----------112----------------1--------33342343341122 6111644-9531338222223231513332222212321122122242223322223222422131121111223231132233234553322333323324164424646582452223134196263FT6-54A433364552233343315243238F832121533367244544h45445JAJL1F91-22233 * b.81.1.4 GlmU C-terminal domain-like
[ 763] --1---11111111111-22222-3112-11111---------21-111-231-1111211---2--3 212112-1111111211----1--31-----12111431212124123111232212-11224211122111111111-21-211111111---22---1-11112------------------12-22112221111111-111332111111111112111-11122-------------112112212222222224212222222122122223432242333333463333333333333333332211212211111331133-1-1212221111111311222222222221111-1111111121-222111111143222222222211--2-2112111--1--11-211------111111211114-----3142442334624-111-111113-2322215111111111222121111211-4-22-22--1111111112111122111111111-----------------1111-22411-11--3222222111122222222121232322111311-12222121122121-11-------1-211122211--1-221113--1-111311222232111112-11111--1-------2--1233222311-23131111123111131112321---2---------22112222222222222-2222122222222222222222221-1222222222222222242222222--222222222222---211111222212111---1121--------2222221-111-2223-122-11233--1---------2---1---1-2111121223222221111--11112222------------------------------------111111-111111- 1111332-312122332322332323322121211111111112124223232412223343322111121222222222122224211421223422313226341446G9E9CBA6649788ED6C7JnB-E9I6684G67A458797A76E6AAAA6A597554E575797214211-111362382843153252 * d.52.9.1 Cation efflux protein cytoplasmic domain-like
[ 764] ----11--1113112-39-122-12--3-22----1-1---1111122-2211-11-2122-1111-- 15Z-6--2667-1-12211-131129111111444435AC211987911514GFF1-41122-585E7A62-------1--15-------42-B11----3-1731P3B-------------------1------11187---221---22------1-1-2-2--22------1-----1-23---331414223232-4-3-322-6533-3332-3312--3443442K-------------------12---34-----24225411--1----1122111-111222111-1111111131111111221---22234--23111111321221111131431---22--131-1---124225-1---G3222-----2-7331112----12111111115-2222274139--MDD8D9IIHKE921-1-126332351-222222223221---1-------------------------------77--11--1477777533336645333312523-1----1158----633-26--------------------12--21-11-12211--33311-2211--1-113---1------------11-----------1-112-2-1--------------11--1------1------33142155445555566-465655755545366566689833111622222222632622384314453--122222222222---------1111--2231112221-1-12222----------8-22121424-33231544-------------511111--1112-----1---------------------------1------1--11--222--1111---13-1--2222-71- 1---------2-26-235337457488341211--1231111121153433784441222221-1----------------------221313114444-333-----3-32122132324322132224A-11-24354-212111334-2-11--14111-222----2-1---1-1-1--113--63142--1222 * c.1.15.4 IolI-like
[ 765] ---2--3222222222-2223233233222223333335333343333433333-2-322-3----22 2322222222222222222-22222222222222222222223222232222222222--222322222222222222--23222233222222------222322323--------------1322322223222222233322222322222223223223222224223222334233222222222222222222222222222222222222222222222222222-33222222222322222-2----22-2---22--22----2-222-------222------------------------3----2----32-2222222-2-2333222---3-2--2232222222222222222--32243222-----332232322322222222222222233333333222-3222223322222322222222222333333333322223222-----------------------------2322222223222222222222222322222222322222222234222332234233333422222222222222314432332222222-2223223222232223342222333333-2-------22222222333222222322222222222222232222--322222222222222222222222222-2222222222222222222222223322222222232222222222222222-42223221223322-2-----33333252222222212221---2222222222323323222222322232222--------233432222222324222222222222222292224322---------------------1------1--------12--2-2222222 ------3-21--2223244222333334523332232222222233232223222322222222222222223222212322222122324222222332241329-231512--1111-1--1------1----2----------1--------11------132---31-1512323F2223253463343322332 * c.1.2.1 Histidine biosynthesis enzymes
[ 766] --2----1----4782-111111-----1-11------1-31111----2--1---11112--21--- -55122-12261-552-1---5--7-11-1-135455ACD-5EA2123-432769222--232--11251-1---3---113------4324541-2--11---642----------------1---1---21-4-11--379313-11221--11-----142-1324112--11-31--1211-----342232332B9C58J26D21421345726242215--14185444443111333224-D565612-421226--21121122311-21-2-1132--111141111-1-11--3-114311--11---4-1--C252-1-4321422D8EC525212A3111C9283C26113113123-----25112111-1-3844BA22211322222221229-A9C77D9A5A3-833371C8-2-51B122A195621311GGGGGGGGD966-914------------1-11--31-----2-43--3B-2----23111311----11-944-255-762419--3332-642271--5-2A-2-1-1-------582415-1A-2-24-811-2-531531--D251113111------1--2-----1-5-11-111--3-2811---3-6368-42211425114-----2----------212223343132-341-4233-412214124424426621-22-13--25-14-2633-622-312121--2221212211---A--1--111112-4--------12----2--3-3212--3222133-1-2211--525711---------31-21312334---1-6161----2121--8---------------1-2----------1--------------1-2-2-----6--- -----3--1-1-----------------------------------------2---------1----------1----------------11-1---------------------1------------------------2-------------------------1---C-----------------2---------- * c.53.1.1 gamma,delta resolvase, catalytic domain
[ 767] ------1----------2--1------------1---------1--23--------2-1-1---1--- 132-211111112121111-11112-11111111111111122221212121121111--11242123331----1--212-21-11144551311---11122211232222222222333312221212222433344---222432322-111--1---121-1211------------12111222111111111111211111211111111121-112111121111111111111221111119111-2112-111111111111---1111111111111111111111111111111111111113111111121113111111121222111544213221432333232211242212311122---11------2--1-------11111111111---1--1--1212111111211111----11---------11111111-----212--------------------------------1------------1---------1111--------------22111111211--31---1--------11211114351121121111153442332311113334---1---1------------11111--121211123-2------1------------1--1-1211111111111111111111111-1111111111111111112222221111111111111111111211111111-11111111111111112222211111211-111111111111111--1----1----11------------------------1111111111211111111111111131211211111112222222232211111---1111111111111211133333242222231 5656323-9131222446224224345223222224423222232233333223223232232555552464644442544445442223724442444534345534526GJEKB57574767796E9Q*8-ICC7558C87A13773265568B66448L95423624557323443O22244IDIK3EB3211225 * c.89.1.1 Phosphofructokinase
[ 768] 23---1685565553735152534A-1458342122252211333-3266CGD2636445311---23 318-412224311162133-34--173333315445A539-31425132222333-151134113-82A3-1-------123312112--2-----1---3-11735-6-----------11--21221---12222233222417222221-122----1-3212654-12111-12-1--131-12313439B9BB8C9699B76A766625877462632342221286-1221212112211231222114-25-3221561-32-2232122211111--211-1---------1-111111-2111323---333-4432233355454443333-1225--2-62131A6421344341123---4125121------1C74224424422221222-128-382591628A6-97848649767A36-39135211134311111111121-1213------------------------------2123112222-111--11121334-2111--514124413643252214-122-331123221121-1--111-35-2321151134112-3421-1732214338251-2---1-1-----------1111235332-131-11-3323313432223346363----311-------1222312221211132-32234112343132222232312-1-21-11111221-11-1-3322-113--32222222222211-1-----1---222214221-1-111----12223211232431-11221111--32---2------1-3231221221331445211111111----1121663244--------1-1----------1----------1---23141243331211 --------------1----111--1-----11-----1111--1-1-1---------------------------------111---------------------------1---------1-----------------------------------------1-1--1-----1--1-------1-1-----1-1--- * a.4.5.5 ArsR-like transcriptional regulators
[ 769] -----------------------2-----------------------2--1-1--------------- ------------------------------------------------1------------------11---111------1--------21-------------1---------------------1-1------22-------1-------------------------------------------------------1--11--1------1-------------------------------------------------11----------------------------------------------------------1---------------------------------1------------2-------------------11--1--------------1---------------1---------------------------------------------------------------1---1-----------------------------------1---------------------1-----------1-------------------------------------1----------1-----------------------------------------------------------------------------------------------------------------------------------------------------12-1--------------------------------------------------------------1-----11--------------------------------------------------------------------------1-- 111144A-511Q11323444444433544354533324445335543445454444464333221111-21221111-1111112112124134143232222142-812KNZLMWNIFIIMLHhdFjH**Y1hOiIJHJYGGSJFHJHGSJFXFKKFH7AK9LIH6HAHE7876-1-1U2322-89FL3A6339HHC3 * a.65.1.1 Annexin
[ 770] 11111121111111221111111-22223232212221131211212212222211111211111-11 -1--2-------------------------------1----1-2--1--111---1----11--211111-1111111--11------2222-2111--1212111211---------------1--111112-1--------1-111-111----------1--11121------------1-1-------11111121111111111-1111111---11--11111111111111111111111111111111111-11111--111-111-111---------------------------------------------11121111111222-111122211-1---1--2221---1----2--1---31111-----111111--11111----------1-11112111-11-1111111111111211111111111111111111111111111------------------------------1111-111111111111111111111111111111111-122111111111111111121111111111111-111------11-11----111-11111-----12---------------------1---111111111111111111111111111111111----1-1------11111111111111111-11111111111-1111111111111111111111111111111111111111-111111111111----111111111111-1111111111111111----------1111111111111111111---------11111111111111111111111112121--1---1111--------1--------------------------------------111 5534756-E44366756656666667777777776577777676666554565435676767455565-67564566-66666664555486654I45445666552576K9A778B6675B79BB586F*82CBA7456929B677695D66A7F7598HE99974678M79763467e67775C67B5A95555454 * a.4.5.43 RecQ helicase DNA-binding domain-like
[ 771] -------------------------------------------------1------------------ ---------------------------------------------------------------------1--------------------------------------------------------------1---------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------11-------------------1-----------------------------------------1------------------------1------------------------------------------------------------------11---------------4---2---------------------------2-------2---------------------------------------------------------1-4----12--41-4---------------------------------------------------------------------------------------------------------------2-2-----------------------------------------------------------1--1---------------------2----------------1---------------------------------------- -----18----------------------------------------------------------------------------------------------------1--nRcomzSPKQLFHIcgUaT**c5mJrLQGOWUGUDIIJMSSLLmQROR*GIUWbeIENPEdEAS5-----------------1------ * b.120.1.1 Tp47 lipoprotein, N-terminal domain
[ 772] 22211122222222311212111262231121121111111111111--1111222223242113111 12113212111-3111111-14111512121158882434112212221222533333--222--3533231---1------3-------1113111--23444621-3----------------1--11----122233---234221--422--21221222-211211211111211112222233134344444245454433445442344344551221-----5233332322223332211114-2---------------------------1--12-------------1111111111111111111111-2221-1------1111132-111321--32--1221221-2221112-212----------11-12211-1111133343333333-3222232227--933634555544321--2343233437111111111----1----1------1---------------11112--111143223225231111-22422222-25232312--43312211343332---1---21111111112-211312-11111-311--223---1--322214111-------1--111111121-------11-111221321111122211112123122--11---------21--1221111121211-1111112121121111111443113322222222222222222211111111-------------11--111111111-142---------11----22222221-31--3433343332321---11---------2222333333324521111111111111--1111--21----------2------------------------------12-11---3 12--233-531122244556337997733442422355333342226554865944511555234235-2115233313133333515598345442231233253-66493654442343444444737V6-657353445345443333555354256A53874212131362---1N1----32545355123252 * c.42.1.1 Arginase-like amidino hydrolases
[ 773] 221---1222222222-----112212222221122222333332234233323-------2213-33 2442--------21--------------------1-------1---23----------------1---12-11112222-122-----66674722-2214-4444444-1111111111111-4545444554422233---22234-323212243133235-41225233143433223222-----2423333321323232221244333333332121111121323333333333333333443412-23322-2-112244-12--2111111111111111111111111-------------122111222152132444555535342222111213-21224-2224522211---52-2412---1------------------1111111111-----------------------------13--------1---------1-------11--1-----2211111111111111111----1----------------------------------11------------------1-1---------------224231311111112---111111222242-1---------------------1-----555411424625555544455554544544-211---22-22256554555555555555-555555555555555555566555655555555555555555555555555415555555555552224-----2222----14-4424233312224-------------------------1---4--2-421-13556666666665544444444444444---122--------------3-------------------------4322245434-1-- ------4-----222222-222253522222-22222222222122222324543222222322222222222222222222222222224224242122-22567-6712----1--------11----3-------------------------------------------24454i444248AGA2C44477454 * d.58.18.10 Aspartokinase allosteric domain-like
[ 774] 223-2-111-1122-211-----321213122-2-141--24254343----212222---13831L1 --11544111-2-2-32----1---1------121242-12-27-13--1331411-111--43122-42-----3--1-3-2--14564-114-2---3-23-1-2------------------44567--86-CAAJC1138-36D512E--11--1-1-2-3-4537--1---------11-2332532-------4---2-2--12-------1111-1-3--1--22311111111111111--1-22-221--3221--222-1--1---3--11--4-11111112221112121111-11311-12211----2132-1-----22-214122-121-161-522661136C712253212333-71111114124132436451211211111111112-1312343173511121243124223732151A11554212222222226622343-------------1-----------2-24112421-1-13234343A222254124633252721225--245334331121264724-131-341-4122223---352---512-242-21-21161253824443--1-415115-F2ACCDC891-1--21-21-4-1-2-3-3-1-11--2--1-1-3-1--361-1------2-3--3325532524C1-932625624573222222121--42342213332344334335-4713223---22212221-----11------1--813--253221-23244-11-2---1112-2411-31-21111121-12-----1-----2-111111121--5-2533233364A6--D5112222--------6-2-2----3--21--3-3121-731112412421221313- ----111-113----1-11-11----21111-1--1-------211--122--2---221-121-------1111---11----1-----31-113-23--32141-1D3312212--1111--53-2-2C1-11311-11-112111112-231-2151--112-121221-111413C33311-113-1-1---111 * c.66.1.11 Type II DNA methylase
[ 775] -----1-------------------------------------11111-------------1----1- 111----1---1-111111-11112-1111121111-111-1111-1-1111111--1--11--2-1-1-1---------------------------------1-1--------------------------1---------1-11-------------------113-------------121---------------------------------------------11-----------------------------------1-------------------------------------------------------1-------------1-111------------------1-----------1-2-----------111-1----------------1-------1---1----1111111------1-------------------1---------------------------------------------------1----------------------------1----1-------------------------------------11-----------1111-221--------------------------------1------11111--1111-1--111----1---------------------------------------------------------------------------------------------11-----------2--------------1--------------------1------------------------------------------------------------------------------------------------------------ ----11--------1-11--1------111122112-111-11-1----23212---21111----------------------------211---111--------21-*d**Z*WIFGJJHIzlF*O**a3rR*FOLEYGJNP5LMDCUDD*IDBBH96--A351--1---51---------12---2-1----1-1 * d.321.1.1 STIV B116-like
[ 776] ------------------11211----1-11-----2------1--11--21------2----1---- 21612---------111-----111------1------------1-1-1---242-1---12--2-113111------------1--11-1--3-----14-1257311--------------11----------111-----515-----2-------1---1-2122---------------12244-1--32323222-22221311----2231-2-123-111-11D---------------1----1--------------1----1------1-1-4----333323533533454512232342----------1-13-11111-1-123------26-91-1---1--1---2---21-6-----4122-------1-1-1-----1-------------1121-----1---11------------1---2-11--2----------11----1--------------------------------2---11--11111111111112111111111213----11-2-----------13----1------------12-2----2----------1---1-11-2-4A----------------------1--11--1--1-42----------1-----1----11------------------1-111-1------1-2-------1--11121--1------12-1-----11-1-11-------1-----------1---------------1-1--2-21--2----------1--------1----1-21---------------------------------11--1-------------------------------------------------------2--2-2122218-- 42339681816-75754634633449354225221335544541133388A9673336434431235732232435638541123542-85446592212364875324FVBADG9ECC945G6IC6H8a*I2KEP4789D95BA49C79J88DCCC6B9CF7KAM5A9D698DL2482P1-391FLPP4V75366446 * b.18.1.14 CBM4/9
[ 777] --------------------1--------1--------------------121--------------- 1342722222221222212-122212111112322222422756-2434211---211--652158558D-2---1--121-2----1-----------15111331-----------------211211111-111131---5112321151-11------7111KMJ9------------311-----229111111112111121BO763D1115682I2-1111-154111111111111111111111---13---------13--1---211--------------------------------------------272B76565844183627641--A57--411327744285-424662111---52353123156B9A8758989855465666448-C9A898AB9B619A9BA9BCC99A886436655644548-------------244------------11--11111-11-----112211232231112112333322-143331311121-1----2513343312----3111-3--------22-241424-2-2--11----12214121112117741----------1------------15--2322522-2-33233333423223344244--3221-------23244233223333323-2332222222232333332232232132322222222222222322342232-233333333333--3111111----32722----1----------22222233474444542324222223332---------152323233224123526676A222------21-------------------------------------------------------2 ----32---------11112111-11322222211111-11-122211111211-11--111121-1---2211-2111-1122-2-----111--111---------21------2----------11121-111---------1---1--1-----1---1-------1--212113513-123113111------- * a.20.1.1 Peptidoglycan binding domain, PGBD
[ 778] ---------1-1--111--1----------1---2-1---1-1----1-1-1-----12-1-1----1 268-4--1111111-1-----1--2------12222-11--224--1--1-1-2------111-112122-----------------244-1--32---134121-42--------1------4211311-2-2--5622---4-1284341-1---12-2-13--3459-1-----1----11321-------------1--1----------------1-1-------11------------------------11----1----1------------------------------------------------------1----111--2--1--1111111------1---21--1--1----1----2143--1------112-1--1-122----------1-225224-3131-2211355435414-2221--2122-2122222222111312----1----------1----------------311-33211-1222211------12111111212121111221411--12-321132151--12222222-13114653514--22243116443232245757FJ42121-1----11--1------31--21-12112191124113111411311-113123--11121--------1---34434434323-43535343334342243231-1-2111----1-------1----2321122---22222222222---1-----21122122211121---1--112-2222112222211111112141-1111-2---------2--11-----332221-232332331-1-1135556664---2--2-12--------------1-1---------1-----2-1--323 1112585-B24223A35433622445433-27364412311251222224-387122663212213262451462342657464243533Q5584B3324227137536Ej5756497645483981A4Jk7-6AH9564967F517321544G6A8476B334942531522641166D42635A59G5A83955435 * a.118.5.1 Bacterial muramidases
[ 779] -----------------------122233223322334333331111113333-11211121112-1- 323--------------------------------------------------------------------1------32122-----1111--11----1----11--222222211211111222343224222223211141------------------1-21------------------221122223535635324553533222224342342223122222423333332124333232432231111121111111111221112112111111111111111111111111111111111121111111111223333333434442733344414122113114435121214111111111-111111111111121111111111111111111-111121131131111111112111141112111211211111111111111111111112111111111111111111111111111311----4-----12---------------211211--111-224-23111-2-11112222322222-1-41--351-314236332332223222122122131-211211212411222222223123238986748555768787576555565665554--2--13--33355576555455555565-5555555555555555555555665676555555555665655864555336-555555555655--342222211111543584355566555566443353344534334543555433445455222222222-66656666676857111-412---3--1--51111111--------12112211-111-121111112111111112-11-111-2-- --------211-1-----------------------------------------------------------------------------------------------2123222111111111421111B1-11111-1221411111111-31111113313-11111---1--1118111111112-22--1---- * g.41.3.3 Prokaryotic DNA topoisomerase I, a C-terminal fragment
[ 780] ---------------------11-1--1----------------11---2111--------111--11 2222321222222223311-12112311111222223273111212111221312131221221224213211111112224212111222212222--111211222211111112211111222212222122333332223232423332322332232234233441311-11311112112212112111111111111111112221211122231212222221211111111111111111111212111111112211221113211111111111111111111111111111111111111111111111122111111111121221112222221111321-112113112122321112332224121112222322222223222122222221222232221112211111311111222111111111111222222222222212111122111111111111111111112122111221111111111111111111211111111222111-133231112432321223232212111111121231222121212121111122222111256648423222222222221211111112211133111111131313222222322223233223--12222--1---11231122222222222-2223222322222222222111216822122222222222222322112322-111111111111--12111111111221312221111222121112222212112233223222432222222222222212211423222222232211212112231111122122221111111111221-1--1-11211221112-221111122122222222311 -----13-753-2132322323332122222124332222312322523431321142242521233222322253324421112122415333232221131333126232543222135322263232E2-224223222222-22221113212351-125431431122333333e4445468962681241235 * e.39.1.1 YebC-like
[ 781] 22314211111111112222121423332422333443433333243433445453422321123122 222--116221-1-11111-11--1111111211111111-111----------------11----1---------1-2322223343222212222--22222232221111111111111122222222223222222111224344443433311111132435543-111---1-11-2222232123333333353333533433443533345443333333333333333333333333333433323144142124444443433333333333333333333332333333333333333333333333333334354444444444433444444346342334322332232222343243223111111111111111111111111111111111-11212111211111111121111111111111111111111111111111112111111111111111111111111111111121111111111222222112223322222222222212111111112111222111112111121111111112112134443344544433132233334112111224222222222222433223333234111111312121311111121111111111121-11111------11111111111111111-11111111111111111111111111111111111111111111111111111111111111111--11111112212112111111111111-1111111111111111111111111111111211111111111122133333112121111111111111111222211113333333222333322-331322233321123311132234223221222 ----12--11---12-211--------1113-1-1------2211121-11111-----1111---------21---1-1------21132-2111----14111----1411112-3421131A1-41EQ3-535332-4344211222322521222214-1211213-1231-1-1711---1--112232-1--1 * c.107.1.2 Exonuclease RecJ
[ 782] 2212216222222323-234342532232223555556776585565666556322222221223-55 2334723222211133333-3333343333335333437566773--1----111111--66713156652----------235533344431122---122114221422222223233333-22334322332--------3223333331-4421211144333343111121311111222333321111111111111111112311111121111---------331111111111111111111-------------------1-------1111----------------------------------------443443333333343264444432443152445437685219732342313531113-----122212232113211111111111-11112122-3112112--11---121111--41111--122222222422121--1111111111----11--1-----------11311111111111112111121421111112121121-11111111111212-2111111231121111211312-23764467686642444334395333311583444444444443333333433333332222113211222222224542324222322--221311-11122321212222222222-22222222222222222222232244322222222222222222222222222222222231222--111111111112111222211111111111111111121112111112222232321111111111111122222222222322111111111111111113334422--------------1---------------------34455353554-4- ---------1--11311111211211111112111111111111111113111122-11111111-11--21111111211111-111112111121111121111-113-----1----1-----------------1-------------------1---1---------1113663N3346251232231142134 * c.1.28.1 Biotin synthase
[ 783] ---------------2--------222-2-2-------------1-2-1-1-1----1-1-1------ 26E2I-2334411-KBA88-8A--IA888888BHGGJCKQ18443G762331CAD239--F47-94A976-------1-------------2-2221--1A255CGD-G----------------1-2-1--1111--121-14-63731-1--111111111-232241-----11----1212-----1-1222222222222222122211223---5413111111AC-22222222222221222351-------------------------------1--------------------1-------11---111----3----------111-----------2-----1---------------D-1A239-----25C55114111-1----------4-11321311BF6-7531A98CA9B911553-8532331-2----------------------------------1-----------2265--2123555665-111-66653233-27313425--227311112-52421122--11--------1-11127141-----1-----11----2-14374AE-4--------------------------12111131-11-2111111-111-1--1--1---1-21----------1--------------------------------111----11-111111111111111------------------------411111----122-----------------3333312---1121231213-1211---------------112-----11-2234222221-1--------BA55BB--------1-2-------------------------1--1-11111-4-5 1--1111-412-23423131222223111111112112223221112222153511411111112111121112221111122111212142321111112213-111469444585134333443373FM2173632334354724343523543323---13232413112213212811232433523253111-2 * d.129.3.5 AHSA1 domain
[ 784] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---1-----21-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1-------------------------------------------------------------------------------------------------------oTjWacaMAJKGWIoUGTE**W-XRdFIFFPHJiSBKNOTSIEdNLJeNBE6Fygo7t7Df**N--11-----2--------------- * g.8.1.1 Small Kunitz-type inhibitors & BPTI-like toxins
[ 785] 11-----1--------1-11111-------11-------------------------1--1---1--- 2332422222212131123-22112321212223333343431-552322214442241133534344453233322222321112211112-111--------1----11111111111111-111111111-132222111311111111111111111111112222111111111111---11--2-223333333343333332111233332113-22222222322222222222222221222222242233232224422222233333333333332222222222222222222223222234322233331431333332342221622-24212122233214413221121222113211-2222-----1-3112-12212222222222222-11311613-31-333344443344321111121-11-122222222212221213-----------------------------11121234424546565344444445555535554455511444433334353322232223642222222111322211-212233222313332323224444211123322111111111111111-2111114521523223422222123222232332531-1111311-11143122432333222222-32222222123222222224342223344444444444444442223221211222222222222-1111211223221382333323121121-11222222122223366764543544443333111111111123362222255333222222222211111112111122--------21---1---1------------------1111111111-21- 11-1123-A521121--2-1--1----------1-1-------111--------1--11----11----1--21111-11111111212121-1141111--1222-243411221111111122121--1--111111-1112122-211-2111122--1--31--1----2-13124---3-3224-221332222 * d.116.1.1 YbaK/ProRS associated domain
[ 786] 11121111111111111111111111111111111111111111111211111111111111221111 2111111111111111111-1111121111112212111111121111111111111111111111211111111111111211111111111111111111111111111111111111111111111111111111111112121111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111112111111111111111112111111111112121121111111111111111-11111111111111121111111111111111112111122222222121111111111111111111111111111111111111121111111121111111111111111111112111111111111111111111121111111111111111111111111111111111111111211111111111111111111111222231211111111121111111111111111111111111111-1111111111121111112222222122-22222222222222222222221132122222222223323221211111211111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111221221111111111111111111111111111111111111111-111111111111111111111111111111121 45222251F542333434433333443664333333344443343333333344333253434444442444544555554344535555623545333333356514B2633353533333A3CH3849e6-65H4343B44891444233362332545435432C55735444775p3254598DC3A64353331 * e.24.1.1 Ribosomal protein L1
[ 787] -----11---------------1-1-12-111-11--1-----572654-E75111-2322-11---- 12935-12112---A9B99-96--C8AAAAA69878698714364554----52111---635-74A1645-111-1-11-1---1111111-1------212122-22--------------1-111-111121566591114-7233322322223113313152214------1-----314111--11255555442-221342-11112223--12-111-----84---------------2------------------------------1111---11211111111111-------------212111111--41-2----1-21112-1111-13-2----12-225-211--1---1--12-3211--111-33121311353541212211111--32422411-11-33322323213-12-1261222221-2--------2---2323------------1111-111----------2-2--12211555758354553345445545534423311334443122332114233211421111-12--234424631232341--1-33232353331527632-121-2-1-21-1-------1-111322243323-1-13332311111322321333--1-222------2512-412222222212-211121111222211111224122321212122222223231212112221--111111-11111---1-----3433122-3111121-111-1--111111-312-3-462432332435414321--------3--1311111322-112222215551-----2-223221--------1---2--1--------------------1------11156-- -1---15-543111263-2625245272322116931332232-324335547534623334-1---1-1--1-1-----1----1-1441434565451312146-1L1F-3112111---111323--A1-11-1-2-11-11--------1222--1-111-3---111-112753D324447258295353-1-8 * c.66.1.44 TehB-like
[ 788] 11--116377777768266462342111---1--43372222241-2-316652-2-222-1351--1 2-131------11123222-22221322222321213775141311--311-32233111113-1-1235211111112111-4A2551112-133------5-21-2----------------14433423422333441111312--11111111-2---121-----1----11----1212113312---------1---------11-1---221--11------2---------------------2---21-----11--11--21---------------------------------------------------1-32222321312122212313-11---1223321--2132-14232-1222---------164421321232------------143-6-41-1--1--311-311-1111112111211335111111113111-611-----------------------------12112--1----1121------1112------21112232122113-3131231-12-711-12----------1-2-642125533454412123-21434323122421-31111111-1-------31323884535514343246666358666445564542--155F22222244246537777777777-7777777777777777776667455544544444444434344465666672-366666666666--24-----11113553433333322221322333333332322355655444454544432---------82224333333323311215111111111233111------------4---------------------------211113333311-- ----112-322111111111111-1-1--11111111-1----1111111111111111111121111111112111111111111211---11-1-112112111131131112-21-2-11122-213L11125111--11-1-31--2--2132121--2112--1121212-1-1D2111111121112122111 * c.114.1.1 DsrEF-like
[ 789] 11121212333333222221123322222212121111232222112313233223222321211-11 1122222233321222233-3211323333332222222224232222211222322111332122323321111222122222222211121122----112121231---------------2222223222223333222323232221222211111132222222111111111111221222212323333333333333432233323333223122422331231212221121112212111121122222121222222121111111111111121122222222222333332333333311111111121313232322322322244222211312231124423312242111212-2112222-----2122211121222----------1-11111112131-211211111111222111-2313232233333333333222221111111111----11-------------112122123312222111111133212222222222332114222111113121-11111111111111111-212213-11111232111122223322122225224322311111112122222123422122113111121221111122111111-111111-12222------21112111222122211-11112221211221111131111111111111111111111111112222111211111111111--1122222222222111111122-12-----11121113111211111111211111111111111111111111111111131111222222221111112-11111112211111111----1-11111--111112-1-11112122212222311 1111232-2-223231111111121221111111111111121211212-1111-11131111111-1111112111111111223-1-21111321112111113-2435354542-45156395234DX5-225221421351-33433--43546337C34223E25327352122K3243323552452222224 * c.1.17.1 NadC C-terminal domain-like
[ 790] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------1--1--1------------------------1--------------------1----------------------------------------111111--------------------------------------------------------------------------------------------------------------------------------------------------------------5----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1----1---------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1----1---------------------------------1--11-------------11--------1----------------------------------------1 ----332-HO13231-1-----1--------------111-11-----2---111-1-1----1---------1---------------1-21-1211-----123-1G3F3123112111112-11223E2-21121-1122-11-1--33211--13-3---1--1312-2-2-794a223EB****-**OJ44766 * c.10.2.8 Polygalacturonase inhibiting protein PGIP
[ 791] 22----1544446545-2------22211121-----------1---------1111----------- 158-A--1223-1-2RH33-3C11LI33333BFBGB46BD-K2d411-----3351-1--322-2167541----1---1119---1-1121--------3-163-2-7----------------1-1----1-112233111-6-111--1--11---1---1--1-3--1----------1-------2-21111121112-121---111-1221-11---1111--43-111211-11111113--2--121--11--133--11-----1---1112----11--------1-----------11-11---------12-2---------1-1-22-----13---211-12-222211---21---4249112------1HCC--1424431111111-1-2---5--9-7654-7553426945556253-334222211111111111311-12--------------------------------19J4-1C85658AC973333288DD444416C3I7C63--221411--86C4F8------1--1111111-12-31-4541122221221-47415331-----5833--21-22112------------1-1-----1-12252-1-----------1-----1----1-2-------------------------------1----2-----1111----1----------------2----------11111-11111---2111111222-1-34---1-2---------11111-----3144442652234552233111111111-----------------22222332--------11--1--------------------------------1----------1--2-31- 11--213-1---22-89D4A588DGA83232442323222222333766789DF23544434211--1-----11---------2----5G29243111231343--16243322512111112431317B2-51411221113111121112612211231192-----13231-2-2E111122223B112321118 * c.1.9.15 PP1699/LP2961-like
[ 792] 11111-11111111112122211121113-21113111111112221212443111211121211-11 -1125111111-1--------2--13------223213221-12121222212331-1--212221323321---111221222111111111111-------12--2111111111111111122222212232344331112152422221111------11214432------------23122213211111111111111111111111111111112122222233211111111111111222222111221211122222222111111122221112112222222222211222333322122111111112221122222222222-2223222322222322311131121122222221123344412222224432322222222222222223-22322232242-2222233332222222222233332211111111143314334111111111111111111111111111111242212222233333343333443433333333323321244322232333323223222262222222232222213522132231332123324544522322523-----------111111111-1112433362222242333333343332333333331-2322211-11153333335556566655-5555655545555555555344333334433434433424334354444443-3333433334341111111112222123321111111111111113333323111314444454533333333311111111113335333333453333333333332222--1311111111111111411----1-1-11111111111111---1111121111332- --------2111-----1-221111111--------1------------111-B---11----1-------------11----------------1-----1----1--21------1----1--------------------1-------------------22-----12-121222V2221-2343-31124349- * c.1.12.2 Pyruvate phosphate dikinase, C-terminal domain
[ 793] ------------------------31221132---------------2---1---------------1 333-4----------22-------11-------111---2-12--1-----2-21-1-------21-5312-------111-1-----331--2------1-112311-----------------1-331--32-211-1---3-2321111-------11-1--1OPX5------------1-------22133333111122233312221122313331--11211121---------------1--1--------------1111-------------------------------------------1--------116113---2211-1-1-22----1111-11-1-323-13-1---11-11-6262113----131614--2-1213----------1-55254134-41-233-121113-2662-12234444211221221121111-323---11111---------------------------1---143343421222116622222254967682-348532224454522231---33-------1--445545111A6198BCB195A8422365554BC-19153-------111111111DB3-4--51124222--15326422332232131311---221-------1111-1-------------------------1-----22111---12111111111-11112---------1----11--------------4444-1315---------1--11-111-1--21-3255754424423242376----------311545445353231123132111------2-223222------------------------------------11-1-2111115-- ----2-5-643-4384345333353333333333333433233344444344333333334333433225323653423442224411135333536331333778-4654576576545445555675EU5-7684554545763554475285355521152231224111331541H1112442347225385454 * d.122.1.4 alpha-ketoacid dehydrogenase kinase, C-terminal domain
[ 794] ----1--------------1--------1--------1------1----12--1-------------- -12---------------------------------------------------1------1----1------------------1-----------------111-1--------------------------1----------1-11---11--1-1---1---2--------------------------11111-111111-11------12---------------------------------------1--1------------------------------------------------------11---111--1--------------1----11--------1-----------------1------------1---------1-----------------------------------------------1---------------------------------------1-------------1------------------11---------1----------1---1-1------1--------------1--11--------1------1---1---1-----1-----1-----------------------11------------------------1------1------------------------------------------------------------------------------------------------------------------1--------------------------1--------------------------111111--------------1111-----------11----------------------------------------------- 3245668-E76154564647585545455465567645756444445664B65676745554453325-333435542452543346558D34B7E655234398928CCQFPGNGJACADEDCSLBT9**N3XONABD9JCDGD9EC7AMCAR8DCBD9LT7BAC6E7C8GFF84553j43434CBDI5A96566246 * a.118.17.1 Cullin repeat
[ 795] 1111111111111111-11111111111111111111111112111111111111211111111--12 1222621223211324122-2222322232334222433417152112132143211311431171437311---1--211131121111111111---1111141112---------------112111212111222211121112111422113323112111114212111112212211211--121122222233233322211221133323231121111112212221222222222211111111111111111211111111111111111111111111111111111111111111111111122111111123111111121261111211-12111111143112121121111121111222111112111441143121111111111113-1111131241111222131241231123-1142322335111111112113311311111-11---------1-----------11341112313577765666767734787626566341122111212111223421121111111111121122121114212121112221111111212133267111111111111111111111111111114322121221121111121111122111211-11111------11312121111111111-1111111111111111111112122221111--1----111113111111111111111111111-1111111111111123122221111111111111111111112122242431312111132111111111111122222233122113434454311111121111111111111111------------------1----1---21111121111111 23116A6-544-2112142824323252233222312122111213633428624332233311122211112231211122211111143216331213322221-3D383135242221334631519E3-42722-2311121111211133111224324235322213411436K3222457877644255654 * c.72.3.1 CoaB-like
[ 796] ------------------------3113-1-1------211-11--12--522--------------2 --3-1---------1--11-1---51111111----12--1-1-4-1--1112-------22---222121---------1-1--211-1-----------------21-------------------1--1-2-23344---7324344411133------25313461------------111------31222225253422552153231232241E1451-----B91--------------1-----------1---------------------1-----------------------------------------6739222-12253731552---933--5--5234461161111--2---114-----------11--1-1--23--------------2-11-1-2--2--122221222111-11--4-44211---------22--3-1-----------------------------1--1--211115334374122166262222225564244--4342131232181-232--217A11-----3-147825412243-842161BBDG6BB47225-25-32111-1111-2---------26411--F6246462543DIEFEA77CAAF8878F9A----31C------42163211222112211-211111111122111111-212441-1232222222221212221111111--233333223333--11---------1-E28---111-1111-------------123JHCHFGEGGDBABEIGF---------4A99GGFFFFBC7GF--23432323------85AA44651--d-EI192------------------------------4------1-- 1---1---1-----1---11-------------2-1-------------1-------------1----1-----111--1---------12--12------1--1----411----111--------1-1411111--1---111----12--1-3-1211---11---2--231--------1-2--2-1---1---- * a.154.1.1 Variable surface antigen VlsE
[ 797] ------------------------11111121111---1111111111-2111-------------11 1211111111111111111-131112111111111112111112111-1111111111--111111221211---1111112111111222211--2--1111-111124444444444444431121A1118-111111111-12234227162211--2112214335---41--2-212111111111-1111111112111111111111111111211111111111122222222222222111111-1111111-11111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111--1111111112144211111325771112112411111111111-2222212-1111333A22221211251111112122-311111111121121813111---------1111111111111111122121113332522125244421125444424412221215111313114111221131343221111111211122-1111121-2-44453126111-21111131-11111212111112111111111111117111121111122221-122221211211--11111------22122231221111111-2111121111211111111111225524555555555555555113331134-877777177171--21111111111213212222111111-111111111111112144-41122111111321111111111121221111156111113232233211111-6211111111111211111111-1-111111111111111111111111111111311 21--311-91111-1334332335443333333342433352333322233353232334332-111---1---21--111111-21-133-32221-1112221211426112243221344372341IQ71339144143C833434333133235335724122311423322-11823122765A5631355467 * d.198.1.1 Type III secretory system chaperone
[ 798] -------------------------------------------------------------------- -------------------------------------1---------------------------1----------------------1-----------------111--------------1----------------------315332--11112-11----3454-2-----2--------------2-----2------22-----12-------------1------------------------------1-1-------------------------------------------------------1------------------------------1---1----------------------1---1-----21---------------------1---2-----1---2--122111222----1--11111----------------1-1-----------------------------------------1111----------------1--------------111----111---------------1-1-----------------1--11----------------------------------------------1--------------------------------------1-11--------------------------------------1-1-1-1--11-1--1-----------------------------------------------------------------1----------------------------------------------------------2-111111-----------------------------------------------2-- ----235-11119779DA7A778C9B77776765546877787566B856CACF557A544457CA9A5CI7C7GAA8BA8FFGBH344785D5479787644978-4U59FHACAE6986667FD5F6o*D1LAK6797C887777774A7897DB7A4345C6423596IUH45561923372CFOP9N953ijhiC * c.68.1.14 Glycogenin
[ 799] -1---1-------------------1111-1------------1--23--2-1-2222221----1-- 1211111111111111111-11--212222211111111111122222211-121221--1121111111111111112233-111111111-1111--11111112-1-111111111111141213221133122222111113111221111111111113121121-11----1----11-1111-122222223222232433222222222233312222222221211111111111111111112232222223222222222233122222222222222222212222222222222222222222222222122232223333232122322223212213311322111112122211122111112111-1111222111111111211221221-11111111212122211122113211-1-11222111121111111111112111------------------------------12211111111111111222211112222111121111111111121111111111111111111111111-12232112321121111112234232221211122121112111111-1-------1111111433223222223333324333343332422--21211------33233323333333333-3333333333333333333333333333323333333333333233333332-322222222222---2-----1111111233333333332232232221222111222222222222323222211111111122222333332224312111111111111-111333344--------1-4------11--1-----1----1---112111-1111111 3411232-621111511121121111111111111111111111111111122212121111122211-2112221111213322221213111111111112222-2E172632433122134C8391KR7-7582544321533541351264623211-21624752321322344I665339ACG1H45513245 * c.66.1.40 (Uracil-5-)-methyltransferase
[ 800] ---------------------1-------1-1--------------1-----2-------------31 --1-4---111----1111-11111-1111111---1111-213----1--------1--11--32-1211----1---111------2221111111112111221-1--------------111211111111111111--4-2113111111111111121112112111111111111--------1-1---------------1111-1-------11111111212-------------------------------1---------1------------11-----------------------------------221211111111111222-1211111-1222-12311--1-------1-----11------1121131-32212----------1-11212311-1--1--1211-3-1121--1-----211--111111111231111111111111111111111111111111111--14--111111112111111111111111111112122--21112121121113111121111-1-----1113211-111111111111-112211111---133-11111111111111111111112-11221121111111111121111121111111111--111311111112111111111122111-1111221111111111112111211111211111112111111211111-111223213333111--1111111111121211112111-11111111222-21111121222221211121211111111-11112111122222111113232222222111111111111221111111111--------------------1-------1--------111 45233451BJ32333233325422422222343222332322312142235695542222221111111111111222221111111114533545333332155614F7QCDB99D54C76A5IR7G5P*81CBE557A978932884775487C8896CC764U3356844972576*54455ECAM2FC6675459 * d.122.1.1 Heat shock protein 90, HSP90, N-terminal domain
[ 801] 11-1--2211111112111111111--11211111111111111111111432111--1-11--1-11 2131321211111122111-131114111111311133382113242-211123211111131-23434221111111-11-212111111112---11-211231312----------1111111111111121111112213111212211111111111111121211111111111111122221-11322222222122222221331222212311--2221213411111111111111111112-----------11---2----1-111-------11111111111111-------------111222111-15-38111111111122442---3-1--12121444121221111211-12135444-2212557881134543333333333225-33433437851-5554537666775622233423444352122222251123112-----------------------------2226222663846656452222558A222223448764613562325446573A823212224222322221123111322211211222111211422121111-4111111111112112222222111111222253323-2422423423333332222332-1-121111111122213314222422222-2232222222233223222232211133332323333323222322222222-22223222232311-------222222246111111-111111114444423111423332224522224444411-1-11-1121313333322123333333333322221111111111-------------------------1----11------1--1-111131- ------1-------1343244646756222333222222221222322343344243334221-1111111111111-2121111111124242222222112222--5-2----1------------------------------1----------------2-31----11111121H1111121322131132332 * c.8.2.2 IlvD/EDD C-terminal domain-like
[ 802] 11------111111---------1---1----1--------------11-1-1--------112---- -1121111111111-1111-121122111112211111--1-11111-211----11-111111-1-111-1111111-1--1111-111-11111-11----11---1-------11111112-1-1-1111--21111---11---1--11-11-------111111-----------1----1112-1------------------11111-------11---------1-----------------111-----------------1-1--------------------------------------------------11111111111111--11-111-11--1---1--1-11-11111111-1211--------1----1--------1111111-111-11-21-1-----1--111111111111111----------------------1-----111111111-1111-1-----11-11-11121-----1111111111111--112211-------11-------1----11111---1-1-----1--1-1-1-12---------------11--111--12-11----1111111-1---------1--111121--2--22122221122221-21-1111--1--2-1--------1----------------------1--------------111----------------2--------1111111111111---111111------1--11--1------------1---1--1----1---111--1-----111111111-22211111111---1111111111-------111--1--11-1------1-111---11--1----1-11111---111--11-111- -1--CA6-221154434223434433633414233342222221223243354124233433223432123343333-333222314465434434443425288C1678GHMGOHKCBE9EDBWO9SEq*I5TEh7AABGBBEAACCB9M95UBKECD7HIFBC69IA9O67A52244O4432243443242232312 * a.118.1.23 Diap1 N-terninal region-like
[ 803] ------------------------------------------------1-1-1--------------- 122-212211111111111-11221111111111111222222-111121-111111---1112111222112222121111-21223111112121--1212122212-------1-1111111111-111111-11111111111222222222222222222222212222222222222224334-33315555565455565633333355533353443333334443333332333333322222142333323442222333322123223333344233323332333334323344434444333333333433325444432343512112355433444322133231112222233233211333311111121111112111111111111111-112112221311222222-22222213411111111211111111111111111111---111----1111111111111-----111112222212211122222112122222211122222211232222223223334222244223323322222311112221111111111111211122122-11544332222223322332233343222332243413433544466434434153344--1111111111132222333333333333-3333333333333333333333222233333333333333333533323332-322232222333--21111111111-2124222212222222112111111133222332322222112122221111111112433533333334335555555343222211111111111111111-1-311111-11211--111121-2211-42-12221122222 11--32--211-----------------------------------------------1----------1----1---------------------------------431-----12-111113-11---------1111-1-1-12--1-11111-211113---212-11112335G544221223-22344122- * d.66.1.5 Pseudouridine synthase RsuA N-terminal domain
[ 804] 11-3--1111111112-111111----------1-1--11--2--2211-111-111211-111---- 1331111111112122222-222242222222222213222332212113321131122233114221121122222231112-----22221111-1111112412122222222221222212222222212222233222422461111242222311221112352123211131121322111111112222222222222322222222221111132222222212111111111111112112221-1111111111111121-2212222221111222111111111111111111111111222111222223122333333423223222121231112322122212121112222-12223222222222232223223422222222222222-322222222221222222222222322222223333223222222222222131211111111--111111111111111-1--122223222222221231222222222222222222222323322112222133212222213122222222221113231311-122111-34332232311112322212221111113222122112111222221133221212222231333321111221111122211111133221323333333323-3333333343333223333222222223323333333333323232222232-22222222222211221111122321112221221213322223211211111121322224422222222222111111111122334444422344124121145722221121221111--------1-2--------1--------1--------13-12-1122231 ------3-1-112113422411333113322111112322122121321243513421113111-212-23223122-121-111112124241111112132234-171244131-31-11--3-----1---1-1---3--21---1-21-1-121112112--321-1-24-311173231211532654323215 * e.22.1.1 Dehydroquinate synthase, DHQS
[ 805] 11---12111111122-21111-111111112------------1--11-111-11111-11111--- 1-224--1111-1-11111-11--21111112211111531121-122----222--1--22332224322-------1--11--1--1111111111-1111111111------------------11--111-11122----212112211111------11111112---1-----1--1221111122444444333232343322443433322212--11111111-1112112111111111111311-22-----22112211121221211111--11------------11111111111111--------113-222222112111112211-212111211--12-11-111111121-2111222122222113221111111112121121112-11511311221122212222222222112222222212311111111111-122111112111111111111111111111111112211333323233333222322222223223332232-122221222223242112111111111111111-222421-111211111113231122--1111-21111211111111-1--------111111543211422232222222222222222223--22112------43333423332333333-3334333333333333333343333333333333333333333333233332-344434434333-121111114444211311-12212222222222222212221222222111111212122221111111112224222222222311111111111111111111--11--------1--1111---------------------111--11111-111 --11121-4221--222232222222222212211212222222223223222234222223212111-1121111111121111112136422473332211645--244454667333334343372Bj5-87453334335423332433434343---24315B23623222634i5553647FC2842122145 * c.58.1.3 Malic enzyme N-domain
[ 806] --1---1-111111111--2----1-----1---1------------1-------------------1 1-3-----------11111-11---111111------------1--------1----2---1--3-1--1----------11--------1--1---------12--1--------111---1-----1---1------------112211111--------111-1111-------------------1----------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------1---------11----1----1-1-----11----------------------2---1----------------------------------1---1------------------------------------1---------1-1--------------1------------1------1------11------1-----11-----2--1-1---111-------------------1----------1----------1----1---1-1---------1------------------1---------1------1--------------------------------------------------------------------------------------------------------------------1------1----------------------------------------1-----------------------------1------------------------------------- -1--686-1-41554GCEDEBDFHFFFCCBABAA889999A89BB9FFHFGILNDEGGFIFH9548653459447655565444447549A6C98A34564H377B-4C5CDCACAF87797B8HF7J9T*A1IAS8775D88EA58766F97I8D78C38677688F76MC8851223U2224656A7F583466979 * a.102.2.1 Class I alpha-1;2-mannosidase, catalytic domain
[ 807] 111-22211111111-11-----13--2213-132--211-22--11111---22221211-1----1 -36231-11111113--11-12--13111111-111113313332--1111-213111--116-42432221----1122-221122111-11322----1-1333212---------------111--------11112--121-11-22-2311---1---113---1--11-----1--1------1-2411111221211122124--13112---322111111-421--------------1----2-1-11-3---121111--1-1-111111----1--11111111111----------------------11312311111112122311233223311-112164-11124231112321113-33512112227331112222155565666667-53533634431184467547744434-245472433222444444442553-112---1111111---------------1111133524----13443433111144253331326245754--544123223-4243-11-1-132--------113222111224--2-11--1-112211-1---1311111--------1-11111111-1112242-3-1332112233222233322133111----11-------32423323333333332-233333334323233333-245-111-313332333333333341-----11-122222222221---2---------11513---------------222122313121886844354122223321---------2333111112121-1121211222-------3--------------1---------------------------23221--11-411- ----54--1-----1411-2--22313111111112-111-111111-13-233--1--11112--------21-111111-------1--11-2----1211242-433BAJ8GB45352467B85B5Ce8-A691734A4674356-363383935723456422443G2464124-C---3252221222-33312 * b.92.1.8 Adenine deaminase
[ 808] --314-132223223321-1-1-333324131-123243322143132325331--1--221112-11 2481311---1---44311-1211441111116111145411-A322-11116331-111-2227162341----2223111611--11111-111----12635-23-------------------1111--112222111--22-1-22122-1---------1222--1-1---1-1--1-21112-2-1333333332333433764422234231341221213255222222222222222311126122121-12111--3421-211------2111211111111111112222222222222211111111-2561433323233241922211-3514-311314332131542233111-3236225------1958--11111133333333333-43732161116-4445532743665--42-33-1--5324344444412222-22--1---------------------------12D1--44212335322111133432113114274564-1-1211--12321441411121---------11111--32-1-242-111112111--1-112114222-11--11111-111111111-1-11111---313413-1--11313322-12211-2---2112--------124-22222222223-222222222222222222-122--1--1--111111111111-11-----2--211111111111-1-311111111121113---------------1112112--14122425362254372343---------12325-1--12-12233131331111111--13332211------------------1--1--111--2-1----13244241121211 ----22--221-1115256543167563332132221111211222448567D82344-221423122131231311-112222321-13B424341-132111---14221---23-124111321415A1122212-3121111122112112-312111221-211-22121-32-6----122423-G--52352 * b.92.1.4 SAH/MTA deaminase-like
[ 809] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1----1--11----111---11111----21-1---11--11111212-1--------1--------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------- -----------------------------------1--------------------------------------------------------------------------21-6-1eR**rZsXPStQbO*5-rOBHzfmYX4*EhXEq*f**Y**e2*------------------1--------------------- * d.323.1.2 STM4215-like
[ 810] 11211112111111111121331312221131111111111111111111311111111112111-12 1112311111121231132-2211222222214223311112121312132121221211241213433111111111111211112111121111-11111111112111111111111111111111211111111321111134213411111111111111122221111111111112122211111222222222122222223111122112122211111113223613111123331111421211111111113211111111112111111111111111422111111111111121111111111211113215222222222213112111211111111211111111111111111111122211111132233222343333333333334-12121112331143322323233423221132213411322222222222121211121222211222111121221221212122322111112111211111111111111111211111111111121111111121111111111121111111111111111211111111111111111111131122111122211111211111211111221111112111221111111112111112111-1121111111111221111222122311-111111111122111111141111111121111111111111111111111112111111112111111111111111111111111111111111111-1111111111111111121111111111111111111111112122111221111111111111111221111111111111111111111-111111212111111111121112111112311 2211223-732122211133112312321321122123233332223312221211122222322222222222132-2323312222213312233333225443124484453683444367333657R5-6683465454713436343343443321233365536363453222G2522664462533283423 * c.66.1.24 rRNA adenine dimethylase-like
[ 811] ----------------------1-------1-------------------1----------------- -----------1--1---------------------------------1----1------------1--1--------11--------33-----------------13------------------------1------------1--11------------------------------------------111111111122111------111-----------------------------------11--11-1-------11------111------1----11-1-1-1---------------1----1---------1111111-1------------------------------------2-----1-----1--1---------------------------------1----1---------1---------------------------------------1----1----11----------1-111---------111111111111---1----1-11---1--1--------11-1---------1---1-2---------------1-------12122-1-----------------------------1------1-----------------------------------1-----------------------------------------1-----------------1--1-------------------------------------------------------------1---------1-1--------------------------1----11-1---------------1111--------1----------------------------------------- 3211659-D632666545756466764444444444455554543433655566447A56675333333344333443553335433336974566565463769527Q7OOKIJJFBAE5AACZTALBm*H3MIQB8C9DD9F96CD94H98HCBABR356fO95T975B67N635G5H44512PPMV1SE53B98B5 * d.151.1.2 Inositol polyphosphate 5-phosphatase (IPP5)
[ 812] -----------------------1-----1----1----1--1--1-1--111-------------1- 11-1----