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Summary of SCOP_FOLD&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbspGo To Summary with VIRUS
see 1-100     see 101-200   see 201-300   see 301-400   see 401-500   
see 501-600   see 601-700   see 701-800   see 801-900   see 901-1000  
see 1001-1100 see 1101-1180 

       aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppasscffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoaf ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa
       ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitmb fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa
       eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuucosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneua aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon
       rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieehhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrcc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo
       01000000012345000010000000000000000000012410003020000000000000000000 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 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000
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[   1] *****************************************************************i** *******************1*****************************************************************************EI*********************************************************************************************************************************************************************************************************************************************************************************************************************7**********************************************************************************************************************************************************************************************************************************************************wB*****prdwuw*****************1****************************************************t************os****************************************************************************************************************************1********************************* *******f*********************************************************************************************************************************************************************************************** * c.37 P-loop containing nucleoside triphosphate hydrolases
[   2] gdWXfj**********u***zqx*********jZkktcp*tsn**z**k****a*******zwtnEn* *******************1**ts**********************************FF************vvv***u****dfzwp****Q*onq55f*w*******KKKKKKKIKJJJJJVflhu*vxvsu*******t**************tmuxux**y*****btbbcYYsWaaY*****rrW*****************************************************************y*****r***********************************************************************************************************c***q*****VWWUi************************5***********J*******************************************DDCCECDCEEIpJFMNFJXJhCHHDHCMNS**************************************Wx***********************lr*uysm********************U******************glkVWVUTSaRbLNPNQNPx*fo*********************************F3S****CAABBB*****************-****************************************************D************CE**hvfgk***************m*xvu************************************V*g***y************************zkmmGF********FHFHCEED*NfB7FBS-CCLHUFCEEFEWUDHFHHGt***mv*wzym*f* *pw****7************************************************************o*************************************w******************************************************************************************** * a.4 DNA/RNA-binding 3-helical bundle
[   3] pnh*ku**********xu**************************************y*****uu*H** *************y*****-**nn**************************yl****x*SS***********jkmlnmji*************j*syZFGw*y*******HKJJKKKLLJKLMMj*****************************************************************x******************************************z********************nniquo*egb****utdmelqgqlskfgjhggqurmklmlnkjmjlaZaZeddfeieYdvuuvurwrtk**************************qr*******************ty********ijjhj************************5***********U*******************************************UUSQSRRROPMNUdWWaaYfVUWWURRTTg**************************************r***************************************************i*******************************zxxxzx*************************************Q6k****WTMYYY*****************-****************************************************L************UVj*z*******************o**************************************oppo*vqo*****************************x*********NPOOQMQO*QuGEIDJ-DCIBEEEBACBKGS9BDDE*************u *******D**************************************************************************************************t******************************************************************************************** * d.58 Ferredoxin-like
[   4] **v**************************************************************9*y *******************-**************************************Za*******************w****************LAA**********aZZabZZYddaabcp****************utx**********************************************r*****************************************************************j**uz*x*******************************************************u*************************************************************dmgdt************************5***********V*******************************************XXWYTWWZUTHWIJQUGKPGHIHIHSMWU***************************************v***************************************************p*******************************z**wy**************************************Y9p****ZSKZZa*****************-****************************************************Z************WVi*********************y****************************************z**********************************ol********VcbVSWVT*R*DEC8Y-LMXTUMHSTSPbwHZNOQN************** *******9**************************************************************************************************T*************************Y****************************************************************** * c.1 TIM beta/alpha-barrel
[   5] 4475H7A9FAABFGD8MA99745Tq9DiJwMMrRLAE8CCDDFn*7L*Ps***5SRVaSQD899I2J* d**4*7CHDCGB74AEF66-6T22FJ56664DNILKGNJNDVNmTiT7LUQHjYfCBH33RXPGzES**zNJEGGIDA76MIB96K8A****2*LK4--Q*JhZ***g*45555558565555EA5F7A98C7l9t***wACA*FSHMGDEEAD55657A569F7kQfis231512151431UbSKNRNCDGEaYiXlhfpPlsolokNbKLIHnplEHDLFDETmlkaRo*6CCCACA9CABBCB957656EA88AA776787755AD674449BBB9BCA7588446AA87898997967768ACA78786964437675UPIeV7777879BBI*9CBEYaKiVsBBZHfO9XWTDEIQ67GCDKV867*F*XHIA37314HHYVXSLKNNPQO7897788987M-WXVPckUWHLB1TPRQYVJYXaNOETHLFPBQPPTTKCJCCCCCCCCDCG9EQRM232344441123341314644333312222CRHJ9FJIGJeVWaYhMPQQOTTYTefaWRbhZdYXbg5CcdciTSGEvOKOWBOOVKJCNP8668787AB9GKRTg*VUKMOLEPPQSN9***jlr*QUmkvo**KuI768799998B6A8877977EA7BGFHeXFZR*dEbLVfYchdcJZcSWVZcRdSYy1-5HJCO--1---fmOLUWYo**yovv**j-*in**m**x****srqvqljgeHPQTbnuhhjsqrqrmotkhodWYScXYcB-qx*x********--4J55556BBBARD*AO878BC9487569669ECDDD6F6ELN*ZZfWafYWVPTVVNXTb778588867DNXcdRXWYVplUjrecfkhkmUWTFFFF96YCRRIISS56635233H9E----1---2-1--2221---1-223NSBFELLMNRC*Ka UTIM***2***S***************mommjkxvvqqnmgolnml****************hcgcbcHXddcXlkiQhhYcdehdSQSn*s**y*ZbZcY*j***3********************************************************************U****************h****** * b.1 Immunoglobulin-like beta-sandwich
[   6] RQKRORsy*******tT*ggddZt*z******chYURbUbUWZhnWikYh*ywWdlXXccgemie3cp ***u*vi****nqm*****-**ww************************o**t******FF***********bZaaYXXQPjj*gcmlb****L*ZaD8Ag*s*******FDEEEEDIFEDDDDb*yr***vy********UUQ*********morsuso*uw**x*****qnoouwotuphu***yzwsQ*x*************************************y**w******y******y*zy***TjH**MpNNO**kl**koimorwv*aabVUUWigfcgeddbbdbacORTRRSQSPRQQQjXWZZRVUVlj*X**qqnnqtussu*txxZffW*dnVM*jica**xyvqjsfimjpjOVd*x*****OTRSV******s*****************-***********K*******************************************IJFKKLMLEEDEEGHJEGJEDEHDGKHLGw****k*********************************Z*******************yqt**hinkjhgsv****s****o*zk**tsvd*****z***********gbfaUgcbchVSgSVUWSUVockkssr******************************B2M**s*FCBHHH*****************-***************************************************qF************FFSmkojmk*********ief*ayQYZVTrhkn*******t*********************vchbXfdZcj************************rhihRM*n******86667677SCR3232A-A6978457669BC768221Wcjjcomnros*px QQMO***1***P********************************************************w*************************************9*************************9****************************************************************** * c.2 NAD(P)-binding Rossmann-fold domains
[   7] 22244296ABCBBD8B37551227D6AJ5C8AE5IDFBEFJFJdUIg*FQ**z4ABEIGD639B229I k**7*77ECCFA98NPPII-IP66TOGIHGGJXTVUUVtu9hZ*FP99FCC8HJLB7A33WTI8*Vvww*M7888675965PEFKTIM****9*ba*22w*Vx**y*h*HGDDDDGHGFIIIIwURZTfMQUpsT*****677*C*******gkacTXONUUxme*****AXGTA9Au9PKCfOPJJDFTHKJQPQNRRWUMVXWUVWSUMLVJRSTJIIRHIGBCEEGHgTB988A898A9AA999878ABD6699AA644755115777534466654457655543536534345453446554544558675554444JVIbSLLLMMNNRNLIKLNMHLHVPU76JGNIMTKRPJHJGIDDDHH9IZ*W*iWXdAB8BChU***YZTYYkchMPOPLNNNONR-cdsbZ*bYS*gBrYVmtss**uvrfhhitecPRQPVUVSLLLLLLLLPSZML*dtAA98977A45FPBANR7AT987888B5987ObsUhISOMLtfigkldPTTSZYkzgcgeYe*mubhjhHTYVaqPRLJZSUjhSOa*aVWfZGEIIIJHIUNgSYmv***jdvkd**lloT****tv*mx******juJMOFBFEGFHFJLKNOKKKLMMDGRWUbbNvgt*S*bdjglkdmlbdeebidiibmy21FibUk342444QGISILLXWYdXTWUXS-VYcZbSVVWYVQbQTVURbOOMTXIMOXQaSdOcZdccXdWUaTNLMQLRPE3LTTTTTRRSUSW117fOWOMPYZcXbM*MZEDBEJC7C8CDDCBMQOSMPFMIPJVfgheikjlihacWdWVWX87999B797LcnneXXZXVivmkfebfZdZcZccJKJK77********OSSSOPQNwc421223-5344611434142244222LHP9EGFHIIR*dh *******4*********************************************************************************************************************************************************************************************** * a.118 alpha-alpha superhelix
[   8] LJGGGHPTTeeZRQVUSVLKIKHcdroTWSaLQKOKNIRRSRQPROJlQa**xNLKNORSUMNRO9EH ***n**q*srn*dsj**hj-j*TT**ykzzwh****u***my*****qnh*l***ec*GF***q******nmedd*xqWZohucTXlb****R*sdZ79b*hvv*w*u*KKKKKKKHILJKJKamjWxqtekvrzjop*zVWW*i***t*z*cdihddcihfj*u*****YZWTaSVZSSVZ**ueautX**y********************v********un********YghewceZgjgggffiif*omz*X**h*jtl**xw*wuppyoe***cianm*nVbYrkeosomixkoedebeecedigdfhaZjibWVWcr*x****************ty*****la*pr*k*****t*wu****tZyhzg*****LTTOazp*****u***v*x***y**y***4***x******uO**************srn*********y************i*u*VVTNMOOOJKOVSTPQSTZVsRPQPTPYUSpi*udlqs*********************s********Sg***********y**xy*ntnj*qcfddbbc******r**vmr**r**tzqX*y*************n*jUUSSUSVTUVXUZZUZZWafudipsq*******w**********************J4cuty*NMJLLM******w**********-***************************************************tL************LLegXcVVZwmwn*q*w***ztjxbiolgnuzuqmxvvhuts***************z****lffkhkiffp************************lkkkPM*fnky*ypRSRRSRPTaSYKNPER-PHKKNJEKQQI*OFKOIIIn***j*****h*ee **fo***8***s********************************************************w*************************************a*************************Q****************************************************************** * c.55 Ribonuclease H-like motif
[   9] CCIOFHMLQQQQQQQOIONNNMJq*VUnV*ekbhkYWWfedab**fw*bt***VQYPUTRUNMLN3Re ***i*ijtpptWfa***uv-u*XX**tuttu*********w*****xvv**p***klzDD***o*******jkkkuidVR*u*MPWZX****G*VZ976c*j*******88888888997777HqnYx*kdm**y*****wkm*m*********z*ggnsig********chdZYYZkaccc*vvfejgRxv*************************x******vvuvuv**konnnoojmmppoqmkijkhmgbVstYgUTZ**nopqXhZdjWZXdhjheWXZjhibdbbaabcabaTWTTSVWXWXUUTpaZaaQXWYYu*y****************luxn*x*YT****g*****qiwxxlgo*Mil*******PUTTT*************yzvzx*yswv*4***********H***************************tttttttt***ny***GGGGHHIIFFBFEDLNBGKECEGECGGIIUv***f*********************************Te***********************QVTUXTVnl*********z**v*****P******************YhfOZVXWXTMVMMMNMMM**fg*fe******************************F5P****87599B*****************-***************************************************sD************EES*UYTUWnqopx****VVVaUfIVVRTWPVd*****kxmrq*******************cTSQSaSQTq************************troqJL*m******DDDEEAEAcCK5445B-897978499AB9H987889aUWaVaYYXXd*qv NLDG***1*WgMem**************xqzzz*****ywuzyy******************rhpZZeMmhZrdoolQmieljnlpmot***********z*s***7*************************B*********************************u********f**s*ukm**************** * c.23 Flavodoxin-like
[  10] 225534897666896C34253331A44L5A56332325245328455C149B7333393244332323 5Z*7*65777797AQWOHI-HS66cUHHHHHMSVYYfM*q6*p*IXI87EB7CBDA6A44JIM6pRduu*W8888999547GC213321262-5-28---3255A566433333333233333423321343423LNNVV111n4*SfcOLTFHAA757987IJJN***o566554484554CCD6711696BLKLJLIMNBLHLLLGEC9AAAMKLADB9C85444454KK4655654456775473465342553364223554444221122464232333532264464354335222222222222243354433327A7A98889A8BA9854998998B8D543796578653658544344-54a4*E888232236BHFG754E7AAA66676676648-ECABAPBB5IC2D77BCAAHDAADAD5I4B85A6976795555555544463E88111111112112233313312212111133B7C9584438EBBCCFB888899FAAA996CCBCBBGA45997FICBADHFFHA79JA99D943334333559AKB9IEF7594-64342-444742654NOSO**3A21--1----1---2-1--22321455567ABCGF7EFB89988BFBBAA97CBB7EC--2566A------57666576575654596-7566866567768457555A887836554344645645846479455656741766676577876115946756DJAD6CV8A433331311123332B7A9B6A7A9C9FFHICEDFDCDDEEGBI2111111118BACB55585ABB87CBB6F69DCB333352B588AB9911------221----2-3433323222334333332-21---2----8C3 *******7************************************************************v*************************************W******************************************************************************************** * d.144 Protein kinase-like (PK-like)
[  11] SSROWPYVYZYYaXbVYRXYWZTi*mp*qswtaWdZXXecfjcYsVixXh*vyXkkivqrhZWYUHNR w**Y*ZdZfdhaWYj*phh-hzTTvyhhhhhm****v***k*m*rjddcbYVijiacXSRoo*Wvdv**zbPQRRYUTWVgfgcZjfhtpmhSmeeZDEbtbqitpvxqVVVVVVVWWXVVVVknmllohhllqksyz**RRUwf******losrrkkkhjfotkp***uegeZcdehbaccnkjoobbYmwy****************wzzvz***utq*svq*vvxxw**r**************rpsqo*hmgrthhlinsrffrrmkmljauwxkhkkkqmgjkjkkljljkklimollknmkmlnkmkhhfhhgggjx*y***********wry**ustq*lzmyvpthgrsqulpulqhijsubhhpj**oq*dhfbk*z****qx*****uwvywvwvvw*5**********pT**************rmiv*********bbbbbbbbnpmcf*u*TTTTTUVUPNYTVTUWVVTTUTVQUVQSTXqo*sd*********************************bk*******y***********jz**ikijjiittx***x**x*q********f***************qxgfgfZaZbddcWbXXXYYXaihYgYom*******s********xx************b6flzqyUTOYYY*****************-***************************************************uN************OOpoccccdtvtuxw****x***xqzxluysr*trsrtnshjn*******************jhiefihghv***************y********zxn*ZczgttkonkUTUaUWVVebdVPZMR-TQURWMMOPOPRMOTSNMMnslkolpfnmYwan **Vk***E***h********************************************************d********j****************************c*************************X****************************************************************** * b.40 OB-fold
[  12] TUTTaaYaaUWaZbfdQXXWZbcciWXfYafbWMMijPWZfYalzfj*Za***mhchhgfYOTYSClT Rv*M*QWhWWTPMU*****-**VV****************K***nsgWQaXHdgnPRa99***S******nFHGGOHHRHMdcVQSQVgdag7aQS944elfrX*rwdkABBBBBBDCDEEEESYaWiroTTstX*****KLK*R*******otllfVZbddu*d*****TZTSRVSdbVPWcVgXaOLOahh********g******llgecd***bebqeXXeYZWYZ**aSXPTQPPPRRRSPQOLUPQWNUMSTJROPOUSQQRSPKRQNHQYcVWWNQaUWVYWVVbcZWYXUYRTQPTQQRUTRQQZaZTTTZTWSZmkksfbgdkipelYmi**UXeXnXzNTafgha*z*anbUdaSQQXgNeZkd**wy*QdRNmz*****y******YabcbZcZcc*-***********J*wx***********mlmk**rluzjtsfeffffffskjbm***CCDFBCDCDCPWNMTWJMSKIIMNHE9FFRkk*kNgjYUq*******z**z********r****uvuyRZpu*qz**o*s**rwq**ogdqyognfagdgskq***p***meu*k**srlf*****y*y*******j*XWWdPWYWXgRpYejnkkYhlXRXbsqvwnr*vwivsvw*************zz***7-R*rq*A96BBCyowtoutlwutmutxwm-uljqqpwlrruvqjkkjjpvursv**qprloploloomvqronpnpkojmlh9xqqqxqonpnvs98TrJLJKK**yz*r*llcbaXhUbcXZYjRcZcceefdkceV*u*****************STVSSUTSTpsrqunonsnwv*rvzx*****z*xjaefGE*jnnsrtoDEB9BA9BcCPAQF7D1IEHGI97FFFEGE7OEBAATTPQYSQUTTr*PQ z*jo***4***m*****************************************************xtxe*wr***zofsqq*************************J*************************K****************************************************************** * c.66 S-adenosyl-L-methionine-dependent methyltransferases
[  13] 22-A-163344454371-636152411B3645213121-11-14614115PQM223354133212-*1 Sx*3c64588734374455-5L228E555553BFDGB9LF5sKeAI885787PHD66A23bFD7Q7HmTXA42221112142-13626KIJH1D683--7N9ILTUuAJ2-------------962E774224J5NIIES122S8*ITLJLJ8566A243526I5vhWmg2666312715416BA1321-51566666684457497674445555819556-2111111CH1333333233223333113213354844435233314132322---111-1112-3222222121221111111111-11232---2221A43E5898777658549884331B3A3275632DB8464-A2267762-1S3*G89634435D9ILI9578C97B88788788579-HGJEJNBHDC31BBBBBCGGG7EC2D56AJ7H9B78BBF6666666698AC5574--1-------2511441431-11111---56AFB73A545BBDFAEDCACBAAAKGLGFACEFBAICA11A9AH8587C984JG22IA4267113323222468ABVV7A25322C62232B88898J65GFBGp*2E3753222221213--1----9724A7887498KL8F9BDABCDGC9EDFDCJDGDKN2-3JB8522122265694835786577685-5757779845575665769688CDCL45575869473686854C56433494-676777767C77322832324223285L452--332-22212--165454444668P9988DEFEADEH8EC9A2n433234n15AA846436DAAFFB9ADAC97881222--A3FF44GF232221226432-A21-1222221333332223332A6353115324u5C *******B**************************************************************************************************m******************************************************************************************** * b.69 7-bladed beta-propeller
[  14] LLKJIOuijnnpoqptKZdedMRmteZpepeXFOIHFLMHKJFCJHKFDIVWPOOTSYZaTVTUU5DG es*b*PJcfgoTRT*****-**BB****************Z***ssaOXrkK***fcu88***Q******k8BBBHHG9L*luWXHMMMLMG9PEE768CoRid*a*hc86757769975666DkrfmmkYXpndqlmefGGDvm****vzocjhigcnjdiimVr****beVTZXbhdTQbfbaSSPOEYkcsuvwxwm*b*wvvxxnijgecxz*YdYhcvuUUUQRS**YcccaccdecddcdchkffbWNLBNM8DEB9ddGGOOHIJPT8NPQQNONDGFINLEEEEGEECECEEHIHHFHHIHHGIIHKDDDJJJQPiVRtbabfaZcnagOThgNYeWgVVOBOKLaT**s*WHMfWYNRVSDHEYO**uu*GMHGIv****xjm*****jorumguknt*1***********B**************hqY**********rqrrrrrrostimkmkDCEDBAABEDA9ADCC7A8DBBBBDB9CAed**kI***q********************Y********Ld*****ysk******tmrcVWR*WNNMLNLLYVYp*id**aiidfThogfhGYPYXZXTcNcbfd**X*RLLDCEHGIED9E9999899TNMXtdhqlkn*u*Z*jmjszusm**qlitxn**x**52GSjjl545444uhvpTokwxxwwwv*wx-yyww*sutxwywvtxrxxv***oloubqonlmpponmjnrlms*eegfeknMFfeccceeYcecbABEdJNJKJdageW*py*ONLHHIIGHHARMNN*****b*dnk*v*****************WNVPOSRQNefghwXZZXZummrrsqqnyooeeeKKLKMKYIwwPOef47743655J7K4545D-A4F97799899HB9A7334MGGGKPIPLOSUBL YYJL***2*kjDhl************************************************oj*SeWTpUSowxfcMccgutu*sZhc*****************9*************************9*****z******r***z**y********************************************** * c.3 FAD/NAD(P)-binding domain
[  15] 55967768777777878767966897A789C88A89B7779999B8AD6D99B77878CA76558666 CGH9FCDDDDEDAFDCDLL-LEAAGFLLMMODJFHFFKIH9GFHAECFDBBCGGID9CAAAAHCGDHHGFDEBDDJDC9BGFA9AA9BCGJHADBB865FHEGDHFFBF7777777899AAAAEEHIIJFEAGCENLLPQCADKEQLJNOIQECABBB8D9BCIKGMNNFB99AA999AA9ACDCBB8AABIBHGHGHJKLJJJKNJIMEIIIEIIHIIFFCFGeaeefbKDINNMPMPKNQPPNMOMPQQMLFJBIICDCJCGIBCKMEFAHFBIJLFEKGEGDGIJDDDFEEEFDDEHKKKGFIIGEFGGGEEFFDGEFEFKFGHFHFIIHGFHHKSIIIMPND8JDMIFOHKHJLKKGJFGKLKLBB9BEEEHEEDDFEDGEEILIDBADLFIHIIJJJIJHJJI1DFHDFSHGFLFAIJHLIHMNNKIKDEDBEFFDHKHGGIGHGHHHHHHDDDIFFFK776789996699BACEABAAB9AAA8A787DGMECDEEEBGGGHGGGDEECEFIEEFEECFEKIHFLDCCFFFDDBBDGDEEJCBCD8BDBACFDFCDGEHB8FDDDIKGCAFCBJGABB8HEKFEFMIJCCCBCGFIC97A9CCDBBAB9DCFFDDE9ACGBHHBADEFDECECEBFBBDCDEFBBDCDBBFCC81ADB9D678888DEJIDDEGIJFGGHDJG-IFGIHJGGHHIFEEEFFFGGIFEFHIDFGEDFDFEDDFDFEDEFHGHFDGFC9FHHHHHHGHHHH97CDCBBCADEDDFBKADAABA8B9BBABG9A9GFDEDDCACCECDEDD9EGEABCFBBDCCBAAAABAAAADDEECDCDDDCECEFEIGIHGFFFGDEEAAHBFFGIED8887A878G7AA6877-66888577768886A78889CB9A7B888CD9G cWMQ***7*mbE***s**********************w**x***z****************ykusupKy*usywx*Xzzvuyzrr********************F********************************************************************Yyvv*lkd*********h****** * b.34 SH3-like barrel
[  16] 6635419DBCCEBCDA2846635EJ77K9EJA3341-121212AH87G34NEA-665777498A1-52 fu*F*XUceefZSP*****-**PP****************G*v**uXLKqcJqyvYL*34u**N*z****cHNNNNONA4BXV44633IGTR-T98A--LzOcl*Q*Tf44444444468787DHFAMNKFHIJJrvudf665*H*suyefZMQVVFFHKNGXSIw*n*mCFBCCBCIBCADnQhFE779JFXutwsxpt*VvsvvrnTPaYedqttDFEcSPRQRRSUSqgFPPPPPOPOOPPPOOWQQMPHKGCKQFGJBJVVEFQRB8DKCHECCKJG5BDBHKIBAABBCA8A8B5555555555555IAB776788A887PUEDDEEEIHIGLKEE3GJEN7GD4TAC52QK633DAA6199H94AJ*3****y6977At****LERptholKLKJLIJHJGg1qr*ur*j*Z**3*zzuz*v***vv*rlupXijUPWVZagPOPPPPPPZUTVPToW5556533345798ADD7BD979AAA52579gr*lJTmfVf*******syzn********f********8Kvs*fgkSRwmuh*aNXmCF7FkI8878767FHKRghgjRSF79A6GF9894LMF9FCQDCbYgY**9I9AB2664524526222212275568DDeYOgXkoYtaPlhqjikslmkiZqkmrbqz1-5LUMN-11---RSZaFXHNZaZNZWaSM1XNPTRSRQSSXXVPOMPOMVadWYumOOLLLMONONNPMPLLNnLJLNJOPA1PQQRRSQPPPRO-13X7A777ZmhjAi*TiA9ASAL376689898svpusYvFUVub********yu*t*c***A9978BA89ALMLiMLKLKbWURQ*******qvrSMJM21CAnnRT*j32212212I37--126-91A2334222495462213FCEDAEFBAC7pES nfKV***-*vnY***************************************************y*irpUujf*n*roVtpm*****bgd********x********5*************************J******************************************n*********************** * c.69 alpha/beta-Hydrolases
[  17] HHEADGECHMMLJHMDKTPMOLIOVKMQNLWIAAAAAFNKNLHGLEFOABeNU7CEDFA8DJHBC18D JKVG*RRWcdfFMHmRUNM-NiJJW*NNNNMNrnsor***KzU****NXmbN***KNz44kaeQ*g****aTOOOlZVFGdXcACEBDCCGC5G562113H87APFCEHAAAAAAACCDDDDD8DA9DEBCVCLBgnnsrABDpbpnnpcbgPWRRKIIMMLRhGk*n*a9HBAAACKA9BAvhWWVac5YKjz*******fx***y***rnms*x*NRexrbWfabcab**HQQRQRQPRSPPQQSTQPOWjeSWcgVMOLPjjJJjeGMLMWOTTXTUUVQOPNSSSWVWYWWTUSUNNOOMOPQPPNNNUSPVSQNNNTXzYi*cdbcdjdUZVdkddLTUP*PNTFnUhIG**YcJPXZKIQOPbCPTIFLkPPS9DA8Gzs***VR***v*u*******w***1**********b9**************WNL**********aXaaaaaakpoTbpc*55444554555454553554444433353GFazMG*********************************FW**************w**MWSV*tJLIIIIJGINj***s*Ukju*Un*qn*BeaXuPXcXVccVip*HjMMMIJMMMNKGBGCB9AAAAJaMGMVR***p***V*i******s*************7-HKYJm322333****y************-************************oz*************************Z2************55CQ69869TUSSNU***dddrYnIQUOPYRUg*****e*Ujd*t*****************EAD88ED8AS****************notolWYVICDD44rpIIDCFEABBAB999N8I89G76-1352435222242943333PbaQNXyVaWKZC6 73239BO-G4648MH9EJCPBBBGPFB97D9BBFA6B9AC9ABB79FDFMOBOCDCFK8C8B8979AA58A6B8897BG9A887BA7788HEECAG769A5OBFI91Pjr*******lbdalsh**f*e***7***eqhc*at*gSmZbU*YU*b*ty*PXml***k*s**Vl*fBfkC*BEDPJ*Zb*DjJHIlgSfK * c.94 Periplasmic binding protein-like II
[  18] 552632BBDBCCDAA84B444659PA9E78IF9AO989FCFGBFEAKMDHmXUB78769BC887C31B Os*9*9BIPQLACAjYVbb-by99v*babbbatooto***H*Z*UZOTEA75bRcCBK44dVhBlO****BBAAA9EABEHEbBAC8Blmnb2jDC2--D*MXO*g*Ew433333343433336DEAJGIDHESIYZZed312gG**t*opaKPccWOTTXQalHg***lDSEEECCVDD8HNKICBCA8GGRWWWWWYYbKbZdbcbYVSQOUZdgCQKTHBPXXXVVOm*BFFDGECCEEFFFDEDCBBFUNGCJOEHJBLOOA8LLEWFDFDGIMGIKFCBCFHFDCCCDECDCCCACAABBABDCBBAMDCGGDDDDGDPLPzVVXZWaaUXRVbVTESYMnLICGEQTEGyzMNBCE9CCFEEJ6FEJCZ*XYy33446gt***hQZytpqlQPRRNRSOQOs1***x**t*s*l4************uuZZS*zrnXhh*kyMMMMMMMMZXXMEyXb11112222222323442242222225264ATh*b5h*wfu**********x********b********8K**xwmjbb*i*o*cemlKYTZrQBCHFGHFFHPYijjqYNTITLJbbMMS6TOMSKLTUWXafV**QSMAE77767986396646456C9CBEVWteVcjgvPjSZWpppnYdYjaXjghbikki2-5HSCa------mmffKoRgpoogmlmgc-sefgkjkjjlrkmhhfjhW***msfkUskolllpmnrmlsklp*bXUcaZXH-iZbXebZZccbc118L46466XghdQT*i*CCAECI6CA96DABEYWebYRfFII*c********u****m***E8A59AA68McaYxYXYXXhoimpafjkikkWYZDDCD53aUqpPPdb32222232J7A25334-3352331554154134111AC999CDBDBBaEV PMHM***-***H*****************z*********************************mxgolOmXMpl*adPZdfuwuqrZhb***********u*****8*************************L******************************************V*********************** * b.82 Double-stranded beta-helix
[  19] 665276dZdfogZaiVCPED978E9EEABADD52542275652MQC9C62JB91AABBJF9ZVU8-22 LSqD*LIfjjtJQPXNOMM-MY33m*MKMMMRcZZbs***KlQ*ZdSMEaT9***QBa44cbWStW****BOHHHdTL58XCQ59658UTQG3M334--AUDIHtFTAc32222221212222679997765559PUVQP765RNDAFFAD85756564985B84AFDK8142211231211PFG76B9DfG*********e******kSzxk****KVVfSQPWUWUWU**MWUUVUXSWXUUVWWbUUaeJHZEaeDOGCKijTVlmLIVWUVRPLDCC87469CD577776567577877A77878877733553423B8D2UhEEEFEHFEDEBPZZ6BB873433E2463tkGDG5DGDFBBH9714F7C*SSo4GB7GeL*lsIARUaTXHKONPJMRKOKr-ba*WX*Z*LoR2*XZddkXwyscgpUOWG9IWB8ABGDHcVccccccVglNHH7J664766662265BEFF9BHBAAAAA74B62CasNGWWMPo*******************k********3F**tCDXKKmLTNxTQeFC9CEdF6667768496FDMGNW7F6A6DGD69C5IACNCBH95JIDHWK7JA7555HGGIE858465454446556FFUQRIHRR7XDMPWTWZNQOWSTJJNKPJWV4-45A5A11-112*x*rW*f**********-******************x***z*Ugm*****************som****H3tXYZccaYYbcb1266SXMTSbbYb7BKOeGCDEDF59B67789ButqnxLlFKMuJ****m***L****MxqyoWdYVoaZW6IPNTNPOQPTPOLNYaSUTUSJJJ85552395DD9998-1-1-111512--------32-11323-2-221---CF9A9DBCCC6QAD 877BobT-*UMGSXn**************************************************e**f*np*s*y*g********ksy************o****4X*h*******ulqqt*u**a*v***3***l*pq*l***h*uod*dY*o********************HaSN*WYVXq*******wm****p * f.38 MFS general substrate transporter
[  20] JH788BGCDCBCDDDGCCECDCBDWPNQQOSP43H55755564BF6DLEEQOI46C66CDBA9784DH QXwIeIIKMNOEFFUPNRS-RbCCaWRQRQRVdRTWUXhjETIULKDILGFDUWWFKL66PXdHSQUaYZJ6AAACCCA88GQMKNJOYddc4RKJ51-JmRVQ*dhNn77777777777777FKMGLKIKKKbIfcdYaBBDVM*oprnmeUSWWWUVWTSceUhw**iORPQOPQQOSQORNPLKGF8MTQUWUVVUVYRUVXWUUQTSRSXYUVRSUXRQQGHHHGGgSKKKKKKKLKKKKKJKMJJJNNBC6DG6F779EGBBDEAD9HE8IIIFFIIEDEHFEDEEEDDFEDEEDEEEEDFFFEDEEHDCBCBDDDD8TOESFFFFFFFFFHGEFE6JHCRAKGIW6ACDQNIQEEIGBCIHG9DDGYBj*nozGFFEEli***dZhvnt*tTTUSTRUSTSn1t*yq***xbry9uiikwvxy*usrm*llnwltdYcbkk*VUVVVVVVXjeQVedbGGGFFFFECCCFBDDCABCGABBB9CADCIqu*pGjtqb*******wnqqo****vsvviv***v***MV*****mwjz**t*dhvvmbbdoWMPPOPOPWbjlszYTQIIGOO9YMHFI7RSTSURRRYjiag**UWKEHDCDFGGHG897877778KHBNWXWmlSjpl*Xsninoutxbsnspprnkmrrq*62FYeVn975777fdadUeaeffcficfee-fekigedeZefeddceedflnmhfPRWngjliknllklqpmljkcddddcdM7dTUTUTTSVUVU99FbFGFFFUSQTje*ahNNNSMQHPNNOLIJPbZfdeRdSbZoX****y***n****uphmNIJJJMIJIbdfemZZZaZmlufgwvqpupqegiTSQSLLUHffRSVV33433332A5B12233-3333352444526233333KGDKMJIHIIJZGQ nfUY***1***Qvy*****************z****t*w*w**xuw*****************mxfmjSrookmxspfntm***syioj*******umuqmxy***C*************************D******************************************s*********************** * c.47 Thioredoxin fold
[  21] 77C798BEBABBDDLEA6E9AA9CMDEFIFHI46954588886BD89A77C7849B68DAE798A299 OVXGS9AHGGGACARNNPS-RVAAVmSSRSSNbbbbWO*uMSMSDEDDB998NHJHCE55OLbCNQYXUSH9999AAA78AFKFDDBFMMPG6ICC521EJACGSEPKJA8888888778888BECBEDIDGEOEKKKKKECEFMZVNPRRLGKJJJGGIEGNMHKQNWMGCBBCDCCCCBDFEEDDON8EDEHIJIJIHJFJIKJJJHDFFCGJIIDIGE9AADCCDCBGGBabZVXRYTUVVbSUFCBBCC8789988887CD679978C797878868HAEA76776677666677HGFEGGGFEFGAC977666777AEWNCMIKKIIKKJHKGHJLBAA9JAKCENADHNOONUXQKUJOCDBHE76NAJOIJKBABBBOXnp*JEPVSSZTHGIIHIIHIGP1XYeWXtYgTbRAbWWVYSmcYXlpdfKJHRSUYXWXVVeIIIIIIIIXLMBMTKJAAA99AAA9A8999BB9AA9A9988A8A9ILSYHBSbVSSrqqqrrYRRRQrsnzbaaaMfvo*kstkEJVWTiaLNKcXjUlfOVbLPMMNNGGHGHGHHFLTgYEMTGPDHDBKHFGD4NRQHZNTYRKJJKSPSdBBBA9BBBCBC898888887BFBBENNOMPOKNXJPHRRTUTUORVRQRSSSPTPRZ8-9HMNN696888NOJNJLIRSTQRPNMSQ-ZTOVPRMSPTWORRRQQRPRUTMOLOLLLMMLNNMMMKMOMMLYPPLPOQRF6KMLNOMMNMMNN779JDCCCCFHFFVKVTXFDEIFGEEFEDGFFENMNNPJMHLIaGhgfichfZfefdcPUSUECCCCCCCCIUSRXJKLKLWVPSRIIMONPNJLKDEEEGDIFEDBBDC4444444486855545-4364433344464433444IPHLIIIIHKFM9C bXVa***-**xW****qytuuxy*xuxzwmvorxtvltzvsuurtty*u*****ssxttwy*reidgdJclbheahkSghjeegadllq***q***vpnmkxt***G*************************n******************************************l******s******t**u****** * d.15 beta-Grasp (ubiquitin-like)
[  22] -----------------------------------------1---1---------------------- --1-1--------------------1--------------1----1---------2-------------------111-------------2-------------------------------------------------------1-----------------------------------------------------------------------------111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111111----111111211122---1-11------1------------------------------------------------3-1-111111112111111111111111111111111111111----1111111111111111111111111111-----------------------------4-----------------------------1111121111111221-11111111111111-11111--------1111--------------------------------1--1--1----------------1-------1-----1-------1-11-----1111-11121112111111111111111111111-2-----------------1--------1111-111111111111111111111-1--------------------------------------1----------1-----1----- B48C***-9-31iaG22dLH8C9466A347434CE36757467344EH5KNMOJEFYG7125211122111-141-11-1222211---35424172331-31421-*o******************************************************************1nO7hAA7M7P***D*F6DBJJSA * g.3 Knottins (small inhibitors, toxins, lectins)
[  23] LMGADDJLMLKKKKZLDNKJHIGPOMMQFJVNLGJIJKIJIHNVTLKYHQPSNDMRNINNPJGGP1HN RsyO*OJKOONJOIobbbc-bcLLl*dYdddahfgfgo**PkilchRQMSRJqjlVQf99vioL*d****TKLMMPPOCHPXTIELHIhdZcCfKL444KjTffzUoTjAA99A99AADAAAACLNMQSNKQPPIgnojfA9DiXaWbUXYeMRQRTUSSPPTVQSherZRTRPQPPTROSTVUXONFGJVWmstwtwryviuyttxweoomektvyfkcjYRTSRRTRQ*oLTTSSSTSTUTTTTRWQPRVKFEBIMBM6D8RTJJKMAJ8EMBIGHAAC9899DJHGIIHHFJGFGG8888888899888KGHJIIGGGELrZanhhhgkjkSeSTpkiOQPOdSYDKdTVROjfTUVQLXMXTQaOKKIjJagaabBB9BDYa*ryUWSogeicXZZdYXaUYYr4fhtdi*aro*X9tiiotw*xq*v*jgUbRglpkkkmpo*YYYYYYYYXccUPhalA9989AA888377577565955765A7D8FPRjPSp*qgt*******z**w********b****wx*uEKjirfkjZV*jrg*oVYZNPNRlUJIGIIJJOLRUZWMegXXMWUTedZXVEegZgYWhaYZbfau*XZSJJGELMIIMFCKCDDDECEOQHKLLMhbRVVTgQXVWacYbZYRcWUVZTWdbYbjA2AXRON674656phnhcnjgiijgjlklg-iheikhiijhijihgghhhx*wpxnxZjghjkkjknkijkijg*ZXbcdccN9pdeejjehkiji98COHKHIIOPORXRoasKKLIILCIHGEHGGLXbaeXPUNSQgV********i***wissqQKKIIMKIKJhWXhWbabbfjhhjXYXcXddVXVDEEFFDVMddUTUW43334334N6724222-2332522333354343111FHNKKKKIKITXRR HD7A***-*bdPmqqs**u**********rrwu***vz*zwz*wnr************xyxxgnpYhlaiicocmicOjdjomihrTWcu*j**v*qjorh*lu*z9***********x*z*****z*****E***x**z*****w***s*xo**********************jw*m*lknux************** * c.67 PLP-dependent transferase-like
[  24] WWNWOWYYYWWWXXXYQVaZabZg*jm*nv**XWVcZYaZYZcYZUgdUaknpbafafXbXWXXXHZb ifxUnZUaddhZWYebdii-ipPPuziiiiig*yuyly**QkhdaWeQRPOOdnrdVfMMwmuTke*iygfKNMMPKLKShXibbcYXiikfOhVVD7CRhXqeqackYCDDDDDDBDDEEEEGZSRXUWUYUZcZXXmnSPSdfvjkqgfZaWXXWVUTTTddbmjgraQSRNSOPVNSPScaZbZSPLWbXabbceZedYgdebedbWbbUaecgXabhYVUTRRUTTnjQRRRRRRQSTSSRQSURSRSUOZMPPMQLOLcdQQPPSQTPNLaWaKKKIIMKLKLKONNMMNKKKOMLLLLNNOKNMLMLMKMMMJJKKYhUYkiiifgffbkbXfdcXWXWXYVOLTOVVZsnnedUQaaPUTXZLRUctjfVVmTRPOTgZslpedbjlfllXXXXXXXXXWa7g*igruuwpoeJmZYehekpihakZhXZVjXaedbbkZdddddddddWbaZYrirNMKLLKKKIIECIHGIFIIHIHHHHIGKGOZdYeQakhSg*ijsmtoopqhrrx*vtvvZss*wYusvTTihjmdeddammndZbXlaSWVcfTTXTTUTZaZlkeaw*renopaoknnlRzlvdseodgjkqkk*m*aYTVTQOPQPRNOONNOONNWaVZUdYhffcmXiThaZdbXYXbdlgcbdcclheqeL8JingeICEIIInbgZhjZihimijilie-ijnljijjikilkgfjgggjihabfggljkhmllllklkljgmcfccfeefUKaWVWXZYUYXXZIINbUVUUWXUUWWbpgjSRNVQSMSONNOMMPgaccdVbbaZqXsrqugkmgjojomegejQONMNQONORaZcqZaaaaggbfgbZaYYaXVWXUTSTOPePUVRSYVEEEGIGHGNFJFEFDG-JGGGIIHGHGGGJHGIGGHRQNTTUTTUURcUX ecOOsuj-*eVNZbzigtilillqmtppsqoqronlijgfehijfikgjosy**hnnsieijgiebXhNjccfghnhQihchgheigikg*cgsewefbaZqf***Fq*m*v*sq**lgldgtd**f*k***9***cicf*cp*nZjghUteZ*asml****p**mb*hr*y**pms*t*opiuv****k**nw*y*zu * c.26 Adenine nucleotide alpha hydrolase-like
[  25] --1112--2112112111121-1M*GJqEkZj--M553978BB**7b*7b*ad221133111111--9 b**Az538ABE334HWTCD-Cn66OwBBBBBBwdfedl**Lva**J839A95ogv95B11ILf3*f****T33334564293QKOHHFKKGC1F223--3S9D9hXasT222211222233334B98BB6CHR*E*****THJ*O******MYVee898998d*Vc***j343323352443*bLHCKNFORUZadZdediOjagifdddaZaXehdMfajOSQDDDDEC**7BBBBBBBBBBBBBBC8876A483883565677667854643666566765555556665666566667777777787777333333336A*bV*ljjkhelQdYLcVVOBDDEMN53S97WV**kucWKaTLHGPD673aSbqZYV57657Wj***XKc*****QRRSNRQPQQh-********bsG5q*x*yvp***ur*kMFFWUcrrmlRpUBBBBBBBBQaXDC*w*221221111---11--11111111112112HZjN8P*rVo*******klme****ywyzTx*******6C**n***fj*w***fhe*Vbhs*l4444444HETy**W**tmu**Z*****5*********ov*u**a*VBEC19B9878243243322TZFHIJE*xitqm*Xpjrv****qvl***tyzntt**--3W*jm------ZUmcNTLbWXfccaaYV-TYdVeYgVVaTdZQVZWUYceadeRTFTKRNQQSRSTSPSPNRdNKGMMJPF-cGKILKKGHKMJ--7T8A796JMLNYF*Z*222423123123455HIIFH9K7G8sm*****************322225222gUstuvstvqpvs**WTpsnruVac434321*W**klyx11-22-11R3611111-1121211121111122111KPFTMDLBCCB*2E PODHpnX-*UXFjeofqsjehgifcYbSSPVSVNNONVSTQSUUSVjrfflgrmVhfdUgegRMMNONELLLOLLMRFLRMLKKMPKMOVicqZfUZYYVchRehi6p************************F*******************y******pv****wh*w**ei*zH**V*MLNgn****n**n*****z * d.110 Profilin-like
[  26] ---1---11111-1-1-111--112--312--1-1--------31-2233132--1-1-3-111-1-- 1111111---111-23422-21224121222221112133344611212-4-12212-2122--4421312-122----1212-1--12233-211----1231131-2------------1-1-21----112134454111315-721211-11211--11-14133--21----1---1-----1---13555555342454554234424435243322332222141-11111111122111111-113-1111111---11131-21211-31211---1--------------------11-1-1111221111211--111112112132-11132--1-1---11222--------------2112322--1---31-11211--2-21111111111--4544352312------11-12---1----132-----111111111121-12111--1------111--11------------1-1-2111-1-235525473333223333331422333111-45312-11122111111---1311------233211113-1-22-22211--212312-3----1-11--1-----------1------1-11---1-112--121212111-211111223111----2---1------11-1--131----1--11--11--1-1-1------1---1-----------1-------1------------------1-1----111111122--3------1--------1-------3-----22223623-32342112111111111--1111111111--13222122223-------1112265--------1--------1-----1---112--1----111-1-1111112 GEDK***-*VSDtp*chviefgffhcghibhegbdcYibhZhijkhggigheildagjekkkfWbdcaDQbYWUZgmOhhbWVWWXWZdkzlhplymildafn***6********************************************************************FUTU*KJDKL****s*lXa***** * b.55 PH domain-like barrel
[  27] ----1---------1-------------1----1--1---221-------A91-----1--1------ --6-5-----2---------------------------------1----1---1----------1-11321---------36-1----65B1-733Y--6I7127G7-1-11--111------*23221123441----1---D-914553111------------2183-----1-----------------43434743-3224321---2-225---2---JWcSO81---------------------211-----1-166----11--1-1111112323---1111111111-3333334333333-11---1111-2-73675878837121332232662-4--21-126-13261------21--C-11-----1--4---------2------------11112121---------21-------------------1-------------1-3------------11EC-2413-----1-2-1---------1111111----1111------111---1----M1-5---1--2-----11---11-------1--2-21------1-----1-112-1------9E-221----------3----------1--1111-125-311111111131111-182123--1--------------3---33-1---21-31114--1213-31--113--------2711322323314113-A9BB69A2-156646533345----12-1298B5--6-1-----------1-----------512111-18247-78882113----------2223-----31122--23433222-----1141168ZT--------G-11-1----1--3-----------------2--------12 LE9A***-***t***UWVTXUYaVQTXXXVTRTUQQSSRPORRPQVUSYWWXaTTWWYTXXVMSSLNI4VQPhVmSPCPOKuucc*HHHl*dW***TNUPnWO**x9*************************y******************************************K****dhb******R********* * c.10 Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
[  28] -----------------------174433234--1--------1------------------------ --1-1------1------------------------1-11-1--1-------3--1-------1--1----1----------3---1-11---2-1----111-12-52--------------1-----1--11--22-31111---221--1-111111-111-1112211--12211-12-----11-1---------11------2-22-----111-122-----132211121111111111-22132-----11-------1-----111----------------------------------------------1---11111112-2-11--1-----1----1--23-1-1-2---------1-1---------1-3-1-1-12-2---------------1-1--------11--1--111----1--------11---------22--1112--1----------1--1-11---------11----11----------1111----111111------2----1--11-11-1-1----1-1--------------1----1---1-1-----1----2---1-1----3---111111-----------------111-111-2-31211221212111222121---11---------11---2---1-111-------111-1--1--------------------------------------------------------1-------------1------------1--111111------31-3--1121-1-1--1-----1---11--1-----1---1---12111--------11111111-------------------------------------11--------1-- 22--521-43-331C448643437555224667547332213475343-378E967568333-12--425373224536623242423288341-3424431512--324**********************3******************************************1664L-1111A3695351317551 * f.13 Family A G protein-coupled receptor-like
[  29] ----1--1--------1--1-1-1-111---------1-----1-11---11--1-311-------12 111-5--1------1--22-2---122222212222123213-241------121-12----2-1-1133----------1----1----------9-------3-1----------------3-----1---1----1211-1-1-------------------2-3-1-----------------111-----------------11911-1---2-1-4---------------------------------------1------------1111-------1--------------------------2-1---111-------------1----11---91-1-----------1-----15--1-----1--------1-1211--21122-----------------11111--1--2-11111112-1------------22222222-----------------------------------11-------1----11-3--------11------111---1-----131---111311-1-1-1--------------1-21-1-11--11-----1-11-1-11212--11----111111---------2-1--12----1-----1---------------1----------------1---------------------------------------1-----------------------1---------------1-----1-----123-1-1------------------1111-1----1------1-------------------1----------------11111-----------11----------------1-------------------------------111--- ogkq***2********************************************************yspvWurpywwt*bxxsvyvu***************n*****L********************************************************************o*********************** * g.44 RING/U-box
[  30] DCDKJGMFIIIHUTKPKJIMKXKMbSVTVUTRbMNIJFHGFDGUONKRHOOOLHJPGJPMOGHEO9KK AKE5836645434456577-7733E77777799AAACE9B77B98544555465645434A8B7B55AA86A77775798BSC75788HFDK9F8A5115B4E9A9965566666645455555D99AEFA9E8BLLKNOC8DQ9KBBBDCH769A666677BH7FJSOC475554375574588998889ABCFCEFDDAADEECGA8QAA9ABAECB9989C9A997BAB8AAABB997ABBA9ADGFDAJ8B8DCACA98FD67ACDGC456BCFB8D87A999699787887A997778999AAA9A868899AC9AADFFJJGGGFFIHJIJHKIIEMMNGEID9FLDB6PLJGBBCCDH8CFD978CB8F88C6886C99DBGB87BA8886656665656B1GF8DICDDFBD5967AAAACAA89AOBG7G7JBDBC8BB999999997CA98C9955667666444A456664564544574BA39EBD698A9GGCCDBEGABABGEEECBBBBBEOEFLIK79JDC7GDOEDIIGDCGGB8999FEBCBABBD7DAJEE8TaADGJECEJFHF8GEFFEFEJNCBAAGJGE364496676986555457548668BBBGNIBKCHDADIGHHJKDILHHFFGHGKGFF815C989742777BCGLDDCEFGBEDECEE-FIEFGFDEDFGDEDEEEEFEDDKFMPGGFIHFHHHGGEGIHHGGGCEFFBCB3CEDEEEEDEEDD336C787787A989FCDDD97999AA9999CC7C9BEBAAFFEDADDFGDFEEJFDFGFDCE7666676667HHHGEFFGFGHKHIDA77A89666C87934QD75767733333333D7786I54-554256523343655444497B5998A7A5A76 RMHOaTd8*gdPgqpflsghrtsrrenjidfhfnhmdnblbgidpiklszveoueppikmlnldffgdNemckgjlmNdgjgilgiibhe*wlrp*kfmhUnh***Jh*P**********************f*****************************************xWcdp*aiZfb****l**Wds***g * g.41 Rubredoxin-like
[  31] --22212-111359F151111127B55431B135B133434321B399AQVCG547545441113-21 PKSDW86B989465IABBB-Ba88EBDCEEECQLMQOIcQ7DTW89B5A895B984C922FC83EBYRWQ75555B8663EC7ABCBBgfUY-XW*F--9cBHJtHa8R33333333332222FC68MENAEHBCDONCP1-1F3*OPbHFU8PDD978769AYGVcqgN492434281412HGA22434GLDFFHGKGMLEIOKIIO9EEDVHWJHWFKJC96GBDBBFSJ3A787868A8BBAC745562IBBAIK967MBLF99HD844578B*99A9P8CD7799C99A7796969BBAFC9AKGD889998886575FK9FQ898EEHBCDAKNEDa646H9G8AFARAJRTJ8BN756C88JN36FJ7YZPQK35545VP*dy*dUYYXVYIMNPKQMmKSU-fqaXZ*oi9eG1ZOPZfWccRWZQRfDLHO8SEsHHC9GppppppppKuqmHGQJ1111----1-3332UY435322332J1Qs29GUS78ED6ITWXbSRx****hiZkVXgdIcOtsIcXk2BOTvOgZkNUoPOLRFKeHFGILR8CDIPTAacekPTBJOJCDJC7aKDGC3ISGdROQArQGGFbRCLCD746666543262322222D668GIKMKITaPTFLFEUZQUQVMWZRQPPgXbVXV1-6EE9R------FIFJCKDWYXPdQOWJL-VQYROMPLOPVQTMMYKLLccaHEOgDGCDCFFEGOFCEIDCGLIJGKFJPF-LJMJJNLJLIJK--CB69769MMNNdIiAIA89787643434Qq6GFHNG*GI7AXRbcceNgZSPTTPRJ**Y8Gn4672bGC*FIRFGGGG*PHRUQTMmWod***BBCB11O4II878722212211D21----1-64714421121431121113D243253339H99 cYLO***-***kkkfngreichefogjggcbbfgagbgccaXZfekfecgkjo*dihfbfgkbYXROPFVXRZSUWXIVXVUZYWWUUUcqXgrf*YTSvTmTomw7*************************Z******************************************N**i*WZaql****n**nu***** * d.3 Cysteine proteinases
[  32] BB648788A8889A8B8BC9CA69QGGSHNKG6873437A796DGCPF5BadZ5ADAAC8ABCA6138 CZeB*FEJLLKBCDaONLN-LQ77XaLLLLKPRQPQlqqiDmRmr*fiVkgByookYf22**iK*a****MBHIIMKLA4HGN44543TPXS3UBC21-GpHQPpGfCQ221131211111119E9879C686FDVVVZXGGG*A*LVTUSIBDIJEBD987JRBgbjoI8D8AA8AC8998tYwEE855EAi********m******ryjjlr***HLS*jtxWWVVVU**hecebeaZddddcdecXYklbFO9XZBDKCGYXHGTWGJJNQORVVXXXPOOOYMMSSSSORTRRRQGIFGHGHGGGGFGeRQMLHNNNIAekfxdbcghpjVhYIPNMCPTMwDKDHUIO93voLCBBAG7583AC5MIM6ObYYd34225WRxpsTJNcVUUXMLMKLJMJMLl-TPbTbmRga*P3*txz**w***oxdURbMQoeYSXXUceDDDDDDDDQOPBGMaO1111111122-5427714722133111134PRTRCVURGXs****yjdffbhhonpmmpQh*piWWgR7BXVQLLWGGYKSRdJFRJDF6C*H7988888EENKLMHYiHGCKKFRQMJP4IJHFD9GGKJGSJzyKLA37827888743954455559F548JIrqKUMTnQbLQhlomjlWVhbcifcenhcu--4DFFM1--111ZoifIlaQTTPRPSRQQ-SOSSSTSRTPTSVQSQQRPw*uYbWbTRNRTRQTRRRSXUTTV*PMKOMNOG-ZQQRQQOQRPSP--9K79677QkUcAF*PsBAAB7A54545554AXTXgYNKADEOIloomp*zucedgcQlvrD665665669jciphhgdf*plztikPTOURPPR989811JKHHBBNO33332223R3D161-2-1---22----1-82-12227J665565448QHJ JCIJ**a3*TTPaal*x*o*****z**y*p*qvwvor*x*s**ijj*z******ps*nnqpkfUTMQPIUKNUORRSFXRNRTVYVZXak*oxu**dTaYkve*hwBb*********krjultn**m*k***A***bysh*iqztWsiih*Zd*uoer*jmkc*nwe*x*****mVmwi*dclje*qp***wsryy**Z * d.108 Acyl-CoA N-acyltransferases (Nat)
[  33] ---2--11565635412511---131121921--1-2------5-214-6763--4-B424121121- 89Q2W7747663838669B-B6229A999997C656879B895F8A957993IIF56711AD56N9KKPJ585555653272721211GHkG1E32111BJ2GAUBP5C11111111211111111123199521ADDEE224T4477633A4122553322372446571213212222128224688348B8888878648979B9CCDD8EA874675678344334BS555555545555555457456553563442377227854444245655445558557778879878755555555555557773337779754CC7876987888D7443A95H5742657627563246455443912662mD88A122136388B453985744435454443617A858DA8786-FCC9AA8CA8AB5675364396D96454444444449761J4321111221111111111112111111112137B62433259689777444465454544347E46674224486673344468664534216111111112173345F371435283773162475385244749R23213A1121111111111111116422246657X83E4448557B515555648B449113325411111165565655556567863-54577645755756547558987746535333433333433338434444421756656656555112122223222342G63222234211-1323233333332116S89886968B65655AA823231333317442878775375585DDBDE67622222193BB55223333332363622133-322322222232322233343332A366B1O86 B878af*1*Ti4OOSeb*nhs*ismrqUUNOSQLKIJJIKILKRPOwloxy***pryzsikmJFMEDFEGJIIEGIJDGKLMKGGPFDFz*jbzvsVRZIRddUWd3x*q**********************y******************************************8RZJ*CLFZN****n**SL***** * b.29 Concanavalin A-like lectins/glucanases
[  34] GF9787KOVXUUNWNPGHHFHHKJTIINKMDJXbK89EAEDDBIRGQPIPQYUAMJKJKKKIEJ929G aU*MnHDNKLJBBCLILOP-PUCCSORRRRRMTVSVRVaWSgiYVSRIIOMLUVYMDGABVPTCeQXgjfNGKMMIFIICWISEGGKLw*wq8sJJ8--KjVcUec*LZ85557556785555NSQPQXSRXWePostwr6BBePgps*uvrHIRRYRUJLNLfSi***xGLGDHKIVMCJMDJHFEG9AHDRXRZQbZTXPWVVXXXMMLLPWVTQBMFEFDGDBBFABXjCBCDCCBBBCBBBBBD9ABEOG69FJDBEAIHK89JKBEDEBCIHRNMOCDDDGCCIEFOCGLMBLBBBBBBBBB9BCBBKGJEDEGGH9NJEoZSSSRSUUXSZHNNNENIGICPBBKZRJGXUOYVJIEHIBEAKFFIQIeYNNS45556YLUVWQLLQOOOOEEFHEFHGHGT-qhpnipjsQkJ7fYYYgfihfkdeWQfNQNMNUWTUPLKTTTTTTTTXWYQWfaQ33233222232279AB6AB8779976485AFKYCJJGGEJbacYaaYTWWUSSdpeeegOZdcjUUNRDJQTMNOQNFGOSOUIONSPIMNLMCEBDFEBPNNQVNEZYcILgkQnaifhJvovliezVfYZUZagXaCAFCAOKKMRLEJCFDEECCEBADKPNOMPXSSHEXDKJMIMGKKPLIGIIKOLJON2-AMNGM21-222NOKLGPLOSSROUSRQN-PSPOXOQPSOQRTPMOQPOOKOLKGNISGNPROPSTQONUOSMLJJLKJMJH7KGHGHGGFHHHH23EAAA9AADDDCXFXJDHDEDFDFHGIEEFHIDCHEDAJFF9bSPOKNVchRPQLWXIaYYMEFGFDFFEFWPMMDBBCBHKLDKMLTSPRQMNNFFFEB6WVbaYYWU54424444G33----2-2223726---7B751---1CFFIEDABFCUsSa CGMNTY*-jFCEnlktnsiekmlt*unaYiXdhbYWZmbdbecXbXzpjj****ttptedgcXPaTRRHaeTSQdVVNUaQYbaWcNNLw*hnwilbXdSZeW***9s*Z**********************C************w***y****************t*u******ShpW*VXRkj****o**ji***** * c.68 Nucleotide-diphospho-sugar transferases
[  35] -------------3--2-22---11---1----1---1-------------11----1----11--1- 14M-1113444--11----------1------13232231-1--3311--1323211-------13-2351----------4---6--2--1----*---61-46-523--------------5--1-1--------------2-D323--22211--1--121144324------------312--1-621-4444433415123321-----454---4-31----1-53----------------1---1----------22--------------------1--------------------------2----------1-23-------1-22-11----1-2----1--------11-------32A-92111-----121421-2---------------1-11111112-11-41131-213-2131-13-12-----112222222212222312558ABAAA56em66UT46S543A82Q8d*111411322211455515111122231111116h83333-12351323334322133523442-11211112212376429--2---211--3182624-1----912462223222322-D-1-----1--2111----41--12-2512-233-3--2422125--1-121-------2-51122441211131-512221-1215131111121113312-1----1----------22322--21-111111111111--1-7OG9BKQHK5181---------------13443341---1144342614132222223111-14211--1111111111-2184595C93334332-19*GGA6FD22212221851-----1---------1--------------------33- JEJN***-*dd*qZwcv*q**********twmw***********st************d***MLJJIHAKMOKHIKMELKKIJIJKGFHNqlv*Y*HKJHHGIfi*2*************************w******************************************D*****y**n************** * d.211 beta-hairpin-alpha-hairpin repeat
[  36] 666569685756A776A4355457LGHKMKOFBDC6647C9BABE9CD8CHCDD986A8775765445 IKhBPCIJKKIDGELGDDD-DK99ILEEEEEGXMPPPPdeDOQeEEEEGDCAQKQDFD98OLTDLIQMPMHCABBIHHGIHHC9AAAKgasf7fFAI11HOEKGKKVJIBBBBBBBAAAAAAAFFEFHGJDFFGHEGGKQBDDSCZKMLGGECB7797A779FA9JLJRE686877687866IKFDCCCAEHKOQOQQRSNLPTRMQPKMNMLLLMPPIMSNFINJJJLLOJKSXMRNMPNMSSSOMLOUMJPFHTGIOFFEGJJJJHGGIHFJEJKNGHJJEJDEEDIGGGIKGHJIJLKMNMHLLJJLMKELLEEEMIJHEWILOHIGHKKJNKILJMLGGFFLHMGHHIQPFKGRSLIKPEBFIFGGLBIBcSJKMEIFEIIMTNaTHDJKJJLEEGFEDGDGGK-XcXZbXUQOeE9LMMRIKXYNNNQMOLHIVMMNQMMIOJMMMMMMMMXLJJKMJHBBABBCCC88JhA9CBA999AAAAACBDB8KQFKFHIGHOWRWSUPXJKJJZXbjOONLIMRaVHPdaAFZXRKLMJHKRWLLILIQIIGKNEJGNKKIKIKKZFMEJXMEDELBWEHFCANONOPMRLWKIOHMSLLDFC8A666676868978788D8B9FRNSUQSTNILQNRNTSUQPNNQOPTJWOPQNO61FLHIL454555RQQUQQRTVWUTXVXVT-UVTWTSXSRTUSUTSTUTPUYSYRddRSPONOOPOSPQQSONTWVPOOOPPI4UQTSOSRSSTPP57GHCDCCDKKLOKHPKIIHIHIJIHGGEGGIILJKLOIKJJFJJQTYQPZPXPURUVOUUSBBBBBBBBBILKMVONNRNYQMNNTKVRURUMLOLJIK77GAGGBCDD66667656DBI56359-9A9797756589A78BAAAEEFEEDCCBCFOCD JHECmt*-*LJAOKZKVXXSSTSSVSVPPVWSVUVSRUQUQQUURRNXTScTZXTRcUTUSRMIJMLMAGJLOHLKIDKLIKKLHHLJLLbIVRPzJMOMFPOgfmBw*l**********************m*********************************u****m**wJWqU*SXQUR****c**KRj*iok * a.60 SAM domain-like
[  37] 541126564334538456445244MHII6BEI43142-677565D58a27A892C7A6BA45425246 GTb8PD9AAAC888LEECC-CK99JHDDDDDEJHGIJHHEADEGLD9CL9A6GHG7EF46DCM9VELZUPD6887C88436273CE77SSVP1K66511JSGJGfCQLV22222222262222H44186631494FHHGM432LCPPLBKJG8ADCDC8899FD9IHINN5947546A5656BBF65447APHacdbgaakVgbdecXGJKKQIbedDGHoGJOBA9AB9kT8889867577998874565479B5BE5698B8CAAAA6A66797AA9999756855666667866667899868789878999666A998EWSi*aZZaacZWekO9igOCC6hOK66HHLODfjILEEQIDB98CF775UBJaXXP45547DBeeiB9ERaLMZ7777777677D-LNVKOEOQCF84SST*adWkfaLLk8LEGBC8GFECHQ876777777GJIC8qcm332353342225324422412222222232FGIDBJIHGIWXXWYU*QOQOOOZaXWWZIUTcdJTLQ44ROVXMdKIfEFZICLUPGDFKlW557666578A9LQaPHDQ9NaLooRPV4bWcUNZWHPWYQU*fCBXFDC3CDAC8B6C7656666HVFG565vf8QPPaPQR8q***zdccvqtphoZrqtj3-7C9HE211222OeloGTLEFFCFDFDHF-FFDGFCCGEGFFGEFEGFC8A9ghDBGJJGCHIHGHGGEJDCHNCECEEDG52NFGGIGIGHKHG246D44444DCED9BoLq888655433345445BBAFC87779FQUWUSakivZUTUYaxrv634346343KMrmlpoprocehz*UUnmpomTbbBBAB32epccGHOO78788777O6733432-3345534223343325333F7HHKBDEBB2PJI L*66gcw2*VfKmidiwgbbfdgsfrgddSURSbdXZYRZVaaURWQTYfor*llelZMhcbLNKLNNBGMJPINSMANMMLLJLLLOSbpbw*mvSOOHQUOaWp8q************************Q******************************************Jl*Q*YPYnOvy**f**js*t**e * d.92 Zincin-like
[  38] 4424D486B9AAADIOI8PWC89C8335394355A5D735454E74FY48YGS8A88BC7A5528532 BQe6d426669445UBCBC-BP66EQBAAABDRMMOaZiV7DAUKP9DB877QMF76621MIG3fAUWeb7A66688765E9577FFD****2*87611E*FVV*Q*I*2111111364111142248CB379K6CMKVY112I9jLZeJKHB8BCC97B67KPCIRkaC455555544555978BEHA39HGMNQNOOKXIKPSNONoiUTLQPLPHPKfFOOHJIMHFr*AGGGFGFFFFFFGFEDBDFCJ8752285355CB337435938A334897B998977988789998997A9989A98A999B662216663haSS*YXYYcfaVbQuZTTLIJF*PPC9DWgMAvqQLGNHEFJKFGm69EdKWdQQM42442VSzowD9AhhSdaFHHHFEGFGGQ1aZgZcgXrQkM2*hhgplx**ygoSMHJLRQZUOTWPRY99999999FFHA9*Tt2223333412222244-3831111223223BMiFDRRNMY*******popf********P****r*wr35jileNhRP*TSgwZPmcKKPR*O8966979JFCHouOZJAG9QOK*vWXb7gUjZSZkMZWUYaWp7BM5DA299AD46473544566HKAFB64tiRTo*qLcRIQcWXZXMVgVXUWcXZQip117GFFR-11111mcxyUlXbihgcdffie-ifYgfagcffjgkceadbXoyrvyYUYnlgkmkmkjlkiohkmkTYRZUXZH4gdceigYZfbgZ329F57546AADAGW*W*888A9F58766C668bbcfdIaBLAXa****z****w***lwqw444445444DYeeuabbdbetnhmlweaiacSWXAECE12yIYZGIOM999H7EH8GA8--2-2-2641151111442232443A5689C8CB94f6H DC8AOVb1nJLBKIQHEJDHBJIJHGHGGFABBGBFEFDFEBACFFGNEJTNQOKIEBAFFFIADCAB8CBDDFBBD7FGDABCC9EDEKUGERNQCCDF9KDFHJ4VcZ**********************P**************************h**y*u*k*nx*p*rmFHMG*HNJDH*eu*KpMKMhYUYM * a.24 Four-helical up-and-down bundle
[  39] KKEFJLEIIHHIIISIJECJIJFCJBCFIGYG8ADEDCEDCDDBCAEC9AHJCGPNTUURPGBAO38D KY*DVMFKIIID9COQOML-UQDDPgMMMMMKSVUWLZegDQKLJIKJDFD8OLGNGN55QONEXNdWZWHA777C9ALFEGSB8F86IJLN7OEEB33ETFXjeHUOT57666676777777CC96BA96BADEPRRPNAAARROLLJLJI8ACEBAC88ACEAMNNPK877798877778aKQIIIHFPLacffehhigejjihlhucffWdgipaVehqTSTSSTTP*YSRRRPRRSSSSSRTRbPQXVTGLDKPFGFHDEGDDMLBEBFIEFFIFGFD9BBKEGLIILLJJKJKJDDDDDDDEEEFCDIKJLJEHJJIJrXVfacYagXaUZUN*WVWWZZXgNLJXNGJCXTHIKCGjFKPUTHILIzATVXXU67666IGwpyLEJWRQXMGIJLIIHJJHd-NMdLKbKdVkJ4xbbdWYZYcfdZXNRLRMabTOTRTaiHHHHHHHHWPPJHLPO442445552244444444444444445356MUaOGYokTZonnknoQWXXQggeobcbcHVzikiprp69YaPMJeNRqTkRoYDJEEAA9MF888A898DEFHPNNMWFHDIKEIVGFH4MEMGFGHKGLMNJZdETGIGCBGFEFIDAAAAACBAAECEHHEDXPFRFIYPZcRWWVWVPViVTTOiWhcOgf41DFICG873999XRoaUUUeggXeYZZcc-eZddfaaebdfababdbbcmroaXOQTUUVUTSUTTUSVUVUTjXRTVVWZK6TRPRSQQLPQRR666QCEDEEMNPMEBVUeFGEKFLBEFEEEFEKFEEDE9GCDAMHaaYaOcVYISbTYJYRXEDE9BGFCDCRTRhLNMMMZXQRSQRSQSQTLMKABAB44GQHHEEFFDBBAACABR5D52728-8586B54777566367566JOMOLMROJMHMHN 8857TYa-*eYMSYcej*q***p****iiYfZcggcXbabUdaZbYgT*********wXZUcVWXOUWHULOaMULJGKPQTUSYXGHHcrRjddcQMPMLQShdd1euz********st********x***6***o**u*v**tn***o*su****y*w**x*****y**o**iKacN*GHJPY*t**s**PO*t*wd * c.56 Phosphorylase/hydrolase-like
[  40] MMH5LFD8OQNPMMOEbENNNKCChKMcPJWG88464ACCDB7ACECJ87dRJ4KPMPI9GHF9F-65 788B*KKOPQY7M9UMOKK-KYAAO*KKKKKLhilkVt**JlLl***Nm*wN***GLu44fbeZ*e****aYSTT*gbGCKCX55556555537224---12-1652A26666666777777797758876C7C7gonrp777ojOPPUNNORYLMECCBEANMIJcWUI7D87756E7875xmQRUrt2XMUiililkrsYhkmkgm**jjcfijoSTmtqUTZZbaZY**JQQQPQQOQSQQQQPMOMKKaQNMVZKDJLLSTDDWTFGEMOQJRVUWUYSSTMQQXbbadaZaXXYPNNNMPPPPNNNNRTRONIRRRQdpOZvVYUUWcWNUNgVRRBPOM*IMXIyHgD7utOOBEuS9FUSSmBQOA67DDDCEBDABRM***FGazef*W*******w***-cb*YW*Z***GA**************377w*********GFGGGGGGQNPBHLIs55453333331111221111111114456I37BC6r**********vk**t********i****wj*p3CljkmTgUXve****QZO8KCElQCDBBBABDB9FNDHJ*9TTacIGeWWeDHG88DDHFACBCCNY9PABCE5FEFHCB7A99A98996H86977ifmBW9E8D9vAFEFF7DGFFEFCIGDFHC5-5EFCA------****W*squuosooorq-trrrqrqtnrtoopqpqpo*****QQallkimllklklklkjl*eiejjilP1v***********22C787878ABBBC9up*TTTNPPFJLEESGIQPPPNQ9MENMgL*upv****p**x*X***955559655BaggnjijiilotsqA9FCCCCBCC9999125K66666588887888L7SE9H6C-F9EAEA87787E78GC555U*ufam*knj7G9- 1-12111-1-2-151112-1--111-1111212212-222-11-1-131-1-1-1-121221--2---111-3--1--1123312112-33-1233231-14221---12811451-1--223222-424N2-21712-----1-111--12-3-2-3E-112E2232-2H2363424--11-13D13D1--1-71261 * f.58 MetI-like
[  41] 862223BEEEHEEFDC1374754IE668318D333231121112312311212121113337884-33 ABA8l626333D59***ll-l*77**kkkkk*********6*G*68886685CBC98B11YUo3TQidThN311144536AAG1122555A4255611-6NEGACDCE832222224242222444355B33337CCBJH667HC6787678234411121133437BH2121123221123DDDAC666I98DEDDEBEEEFFEEDD9AAA9ADDIBIIGF56333322EA5333333243333336223344345642323773366644443212444475733344444444444555555555555535422255564995DBCB8B9A7B9979847645A77492254IH6JGI65D48846363F34ZOOe66666D8qYlCADcPcbVGGFGFFGDFDG-FGJFGQDNKIi3UJJNIHIJILHIMWDaGFGHCBBCGCN86888888H5624GF8222232221223222222322222222226UZrV4DeRJbPTWdkRONUUOMMbOXXXXJVsSws***9CSTKMJQQOeRWXgoAFG5A88BD3334433769OHF8xMS4152181331-HFG5M6HE6DDFCMOGD444343333332322222222A42444A98DLCGEKI7DBCCBBGTACDCGDRGDHH2-5883622233388DA677899B8BBA79-9889A9A9779AA99899B9BA67EC9CCCACDDCCADBDBBD8678766742788898878898343B98A88DDBF9TJAA556667634445446VWWUWMVCHFS8hhfiOfRaTUVTROKIK75555555558767666669B69BCCFBCCLDDD33333365FFEDEF222--1--325------132122-11121113111178456575854H4B HGEJ***-*QUKlm*ppttnoposfkwsremajmljntnpmororphhionnq*enjjjkjipfgXWWHXYaabcacSddVbbbfcddcr*wpvvrliihoqu***B**m**********************V******************************************QijU*YYUdi****s*ujj***** * a.29 Bromodomain-like
[  42] 11111111111111111111121EuCDQAjWa12G21244445ss4W*9YkRX11112421---1178 Z**7*99CCDD968DLMEF-ES66MSEEEEEDZLMNYahaFiTvaPCDFMHCGMO7A922ORj9yTX***W9999DAA9DTDJ55ABAtt*m2*98822A*EXR*z*jz122222222212124CA8GG8BLNcA*****REK*8*p**llPPPII859CCBbmLn***f7A67666A6786cQJ78686KObhhpgpnnnUolqwwpbZYWVZorxJSQmLUNHEGEEF**CFFFFFFDFFEFFFFEEDFAD7A8IG86759CB67HHA969B5799DDBCBBCEDD89999B99999A99999AA9BA99B9D775A9BAFxba*aaZhhgeedYSpjiJQTLjVZBDSTbU9wshTLFCKCDCAHF688vWl*vvoAABBBUZ***dQT**pv*JJIKIJHIIIS-********Qrk6flkopgbt*ngfimWQcRMXgdhePeMFFFFFFFFJNNGI*oq5555544565j*557756765655654455HTgGDKLKFT*qww*yqaceZpo**jiklNgx**py**38nqg*rwVW**y*vLbjrTWPQmN5657765IGThy*n**iTR*mF*****6*******c*******T*b9EB7777756464454555bbCFWFFeVKphvsPrbUkghmiRgfjkicijenfvs3-8LQSV322333USSQOSLSTTVSWWWRS-TURSTUURRSTUSPRSRRRWVVSRLJHUSSQTUTSSUUSUTQUcQOMPOOSE2TNQPPTRMPPPO119IABAAAFGFFMX*Mq88997736586667BKLJHLBJGLDad****x***m********655536645MUbXnghgihgnlqruruqurpdfiEFDF34*9**UYnm45455445A33-------------------1-----AF9B9B89BAA*6K 7A47RSG1VSB7DCnSUZWOQQPROPMFFEGHGFEFFKHJGHJDHFXULMVVRbPOKKJLLLDCBBA98EBACDDBB7ABBABBGC877IQFUIPGLJJHMHEQRX4QinkVWROUaKHOJMRJbqPfG**Q2mVkKKKLTIMUJEMNIJOHDaKTNMaFQXHMGq58AGOGDOFAKMI*CDDEI*Wf*ZnmQJlHGGM * d.122 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
[  43] --------12111221-1--1-------------1-----------1--------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------1---------------------------------------------------------1----------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---1-------------------------------------------------------------------------- 6757KER-R97BQNWVVWRUWVPSWNcQTQPQZKMMLUGPJLRPQQPbQTeYhcPYWVUZUVJGTHFKENQOQJLOPFKQHRTPNQHFESgiVWikGIGNEfI***5LN8*************************************************************w**jB89At765CFi*y*Y*a8AXPQO4 * g.37 beta-beta-alpha zinc fingers
[  44] 67949956776766785756854CH78BE7BA74A46475687B98AD68GEG488798773528-66 8BG4B544444435GAAAB-CD66GCAAAAAEBBCCC9JI6A8B986575547778482289C78ABECA755559885799755A47BBBC38665--49557E98AA54544545644334DCCFCE9BAFE9ADCFD554L4KAGC7BIA866777656969ADBMN4A68466C487578866664CB8DDEDEDEEBCEECDDABBA99CCE6AAE9BCGFGGGBCC6A99999999AAA99888896454CE456347844DE5485794657897A78855BBBAAABAB9977777779877778866647669899FL8887788A988D8869A9A2C79CCB8AGGACA687B98779566A8C977957756CADFKBA99999977677777769-A8889CB98H65B99ABB9BDEDD7A778669B9BCB886666666678868G9C334334452254543345553445423244779867666BBABAB98A9A9BBCHAB995BDBEDDEC66AACCAAEBDBC9C8A9G99877965555558A786CEKGF8DC79EBA992FCCBB8G9H999ACYCF444334544333545534337877A77ABC8A968A7CAABBC9A9A9AAA78AA883-78CGC111111BCBC7C9CAAFCCAABC-ABCCDAACCCACABBCBBBDGEEGB9ABBBCBCBBCCBCCBCBC78A998982C999999899992259766778668B7C97A8755356555566687766687679CCCBDCABAECBABABBA5666656667B99CBBBBBCDBDC6877677777888845BCABAABB3332322272511113-1232333222242321332997867B66A7AA5 7748TU*-vTE8UQbSRQSWUSJQROOLMLSNRNMOUSNQLQUQNMPRPTaQUYPTUKMQROJDEAGGBEEEDDBFE9GGGEBKDFFGIRaNRiO*LPNPHbIcfY2cUU*****************************************************************CBKA*KEEHErmw*P*SGMKOVQI * a.7 Spectrin repeat-like
[  45] BBADACFGFFFFFFGGAEDDEDDGFEFEHGFDFFGFDEEEEFFDFDHGFIMKKEEGFFJGFDDCAACC LLOENHKHIIIGJFEJKIJ-IIDDLIIIIIIIHHHHLHIIFJIIJGHFHFFEHGIHEICBHGKHMHKMOMFGHIIJJIEBEHIHGHKLLKKJFKFFC89HKILKMIMFKCCCCCCCCCCAABBFIHGIHJHHJIJPPQPPDEFOJINQJMMIHHIIIFFFGFJKJIKKNLFGEEGFFGFDEGIIHJJLLGIIKKKJJKJKKJJKJJJKLLJJKKJJKLJIHKIHKMMLLLKSBIHIHHHFGHGHIGFHGHEHIEECGGCHGEDHHEEHHEFDDHAHGIGFFFGGGHIIEFFGGGEGGFEDDEEEFEFEGFDFJGGFFHIFGFJULQSOOOOOMPMNLNMNNKLLLJJNEFKIJNKNMOPMPRKMKKKMMEINLLJIGGKGFFHEIKKKNJJGJJJKHHIIIHIHIIIJ3PQPQQOQRKOIGIKKKLNMKLMMLJLJGLLLHJJKJLKJJJJJJJJJILKJJPKMBBADBCCCAAAACDDDCDFBCDDDCCABCAGGIGENNMMMMOORQPRQPQPLLOSRRRROQRPONPNLDGNTLNMMJKIHMLPMJLNKQQSMLIIJJJJJJLJLLOPOTNONPPLORNNNJQSQOOQPOOKMLKSRLKIIHJHJJKIKIFIHFEHFFFIHEIGIJRRRNNTPNQQQURSRSSRTUUURUSSSRTTF2JLMNMFCBDDEQQPQPSPQRRRPRRRQS-SSMRTRRRSRRQRPQQRQRSSSRQQTRSSSSQQSQQRTRTRSRSPQNPPQPOBQPQQQRSPQQRQFFOLIIIJJKLLMRMVNRQPQQNPIPPOMNMNPMMMKLKMKLKNNQQRQTMNQPRSSRQOQPOGHHGIGHGPRSSTTTTUTTURVTMNMNNNNMMLJJJJDDMLLLJJLKIIIIIJIJGDE66666-667768566656F567777HEIFGIHIJJGKGJ PPDHabe6*lUIZadUWfYUWWVYVVZZXSWWXTWRQXUTTVWYXWYaWYZWcUWVabaVUYWTXWWWKRWUVRVbcNcZVQSTTSVVYUweWdeiYVXWUkXmywFa*f**********************C************l*xvw**s*x****n**t*****y**y**fbbfi*jnhaf****Y**ihvvknY * d.14 Ribosomal protein S5 domain 2-like
[  46] ---6-3-2-------1----21-45BA8-429112-11--11-26-2914314121---1---1-1-2 6Lb321------1-12-11-131112211211321222223221E2-11--2-11-------4261-2-11-11122212D7-2-G13654-1633--183353815751111111-------13223232332378846444494--122731--11112--311344-11111-1211----1111113-222223-13-121-1135212111224112-121111182-222211213112222111121-2221-12143--44--1---------11111--11111111111--1-1-32211-1111111111-3877F45468354412444411113J31B129-ML482728N3--3111-5EM64441--1141ORi324EMPJO------------KIOGI5EZ111-34469768ED68551128438B78723111111112551-NG7111-1------3---------2--1---1--6451-3316134235722224433242214236767711333J4B55232P2-1183342C7232-212BEB3F95IKL5LLIBaRSSZ2***z***8N****IH8C47CC666AA5A3831111--5957811GD168494325TSUUT4QiUYWWWRmmY*Y---54BD------6515C-1AAABAB8CB9-AA99899AB9ABA99A99511-551-2967698888777886967739999--533323333222----------121G19339898B8757976778111121--22-276979CBHB594CCBAC---------27ECLEDDDDAKCKI-221-11-1--34313H3664422--------111-------11----1-111-12---11-221-12--4L21 12-2F6U-O6BD57A3785F967B6849654265548725541J64AB89CAB9969969GA6956451635345353263335657427H9799C46412579D61G7E*************************************************f**j**x*****k**G6246j63864mDIMCMD2AIEBO8 * a.138 Multiheme cytochromes
[  47] ---11-1111112111-1------1--22--12-121-212--12--232I441-1131-13----22 1-3-2-1----211-22-----1111-----1------1------1---11---1-------1-5-26531----21--22-------2311-2-----14241415-3-111111--1---------23-1-2-2--21---2-43834431111214222-1233142-1---1-2----1-111--1---4444423445543341-11--44513-111344233331-113121-2222112-11114--1--1--2111-----111--1111--112-------112-21-2111-2-1---1-1-22-1-4-2118147111443224312331211332-1142-11231-1--1-2311-21-2A4664-2---14424--21123311111111111-13224313333-311624295462-153466-3133255222222221-1-133111-------1-----1-13-1-1-----2-23521111-111131311111111133212111-2342--32411422343--11--131712-------1-312246813-131643361121644213--1-5515-41231311311-1------2433-111-25133-6B3-121122412121115113--11---------1-----------------------1-----------1-1-2-12--2------1-1-------------113--------------3-11---11-1-7211111--------2--33--31-12--41-21232--2112-432-11-11111-21-111111-1--186546437652222--N6--1311-------1--1131---41------------5---11--1----1--111 eZVc***-***Ssn*trxbeefalhbcaabZfeZcXVXSUWWXWTVfhgfdfciYXefZXVVWOUSSLKROLQTQSTFORNPPUKOUOOfxargkdVWQRLrZ***8*************************i******************************************J****knmuq****m********* * a.39 EF Hand-like
[  48] 557784BEQLMSCLMDEIFFACBBKBAHEN98DQHEBDCB78CAK3XOJGXdb5AM9BDHFCC98296 MW*IfF9DCCK997NQRGG-GRBBKPFGGGFFVQRPOLRULqcscLQJBQSCRLOPKE44cUJFeMeRPVK989977645D7OGHAGFqmkn7oFG4--LcPSKogkMY44555545554444BMKTRfIPRWeM*****455*M*tn*rrqJNOORWIJTOTcTo***sCIEJHDBOJKDDFHGCFKLFEAHLJMJNIINHIKNLLIDZPPGMHIXGFEDAGI666675NaCGGGGGIHHHHGGHGHEDD94B79AD8697DJKCCHH7HBA87DB8CCD8988A99D8AB9AC97985555555555555GFDBBDDDCCLG4cRKJKGJKFFHHIDJIIQFFGBS9CMIKKIJINHXCPADKA6DLADEMOfOJLY44433PTfbYLFJJQIMV88CC8BC9B9I1ib*qgtkqNUF4gRRXVZXRcRbbZMJEEDIFLHMNFKBOOOOOOOOfbaaViZh22--111---338866B899798883142CDKSA9FRRKXpggeoqfZaaaZY**klkjUiul*ZOOL8JMNGSKMIEAJLLJ8CERQMCPLFCB8BBBBQLYgZZEobRMVojPnkffcPfkjjfXuPcjeihlpfhHKFJBBA77B8FED9EABABLLFHHWRLNDRXJH8R9NCDFDEBCHCCDCEDDGADA1-7cRHN11-111HLJNHNKIKNLIKMIJH-KJIIMLIMKKKILHHIHHJIPNJGTSHMLJMLMLMNJMPMPONRHHGGEFGI1FBB9DDDBBCEC4477BCBBBBGEETGbNJJMIHEG9BA9DE98FEBBGCCE898QRSQTRPSSJKOPJPKNSQGCDBCDCCCENLLFHGGHGNJHLOEHONONMKJKEEEE44nFNMIIII22223222A18--11---1-11-----1---11---QIMGIIIJHHUtRV 35DCYWW-YEGBKRTJLPNQZWTcecXIJILFIHHLIOONLMMIHIUSOPXZeoVPSOOSLNHFEDGF7GFDEEEII9FICFEDHHKIILaKLORLKHJZFVJja*2a*j******ogdUeatd**a*f***4***YeWb*Xk*lRiZUX*VO*dwdsr***j*****ky*****J**b*aYZsq****Q**RUq*m*p * c.87 UDP-Glycosyltransferase/glycogen phosphorylase
[  49] 78A494CBCCCCCFEDB8AH97A7FDFFDEFA76975855665756B67BJKC7DEDJHHE7879134 IMR6aGBIGGIDDBKJHKK-KO99LQJJIJKFTPPSRbYY9TNTKLL8HKKHNNOEBL33WTGGUJhcbUJEFEEGEEH8FHC88CAANNLP4QBA2-1AK8DBRCOEI33333333555555AEF9EEHDCKEH9AAHI566LIWHMRECEBEJJDFEABCOFHIWOXHADA8976D9899JFG8ABBADFNQQYPXVUWIYTTUXVQMKKLJTXUFCENIMMQMMMMMQXFJJIIGIHIJJJJIIIIHJJKNLBQQDCKGJWVAAMPKGGFDDOTVPOPRJHIPLKGIFIIHGJHGFFEFFFHFGEFEFGNNMOOHKKKT6DAVaGJGKMOLRIREOFEEIJEOBEG8IKKABDBDBB9DA88A9D869IB7GKDDG22423KGTMXKBBIIKKJFFEGEFFEFEL-KJJJNSJKFRE4UIJPPOQTROPQGIFHCHKIDDCDGGFBBBBBBBBDHGABBFG1112111211112244243212222114168D9D8FLMJNTRSTSTOKMNLRRUXNKORKSUPZGLLM6AIJLHKJJHIPOJPICGMBGBEQC999ABBA9EFLDGIEKACBFB9DCAAF6CIDDFFDIHDDJDRbBJA5486ECCCBA887A6897788A9ELMRONJLHCCFGVGKIIKJMGLJIMEIIGLFK2-7GEDE221223VVQNPVRTUVTTTTWVS-UTTVUUVUTUWTVRSTRQVSYWPSJJMZTXTWYXWWUXVYUUYRPRPQQSRF1RPPOQQPOQQRQ343DBDCDBFFHGEFPJOEEFGFH8CBBCBBCIKJLLKEFAFBNBTUTWMQMVKMPNNJVbUBCBBACCACFGHIOJJJJJORUOPOLJKJKIKJJ7787A7FJFFCCFE5855555585D8B847-B798D846778CA67B5555DA877C997BKD8 OONOjWV-*niOcgogkrolstnvsvtacfiihfggWjcegegfcgijjo****ejnljmohXYVTVWEUZTXRYdbQbcTVUUVWgYbc*gkkjwabfYY*Y***Cc*o*******wmmfkws**r*t***7***bjpj*sv*mVrnoS*ke*z*w**c**ouflj*dg*g*pdi**p*rrr******t********* * c.108 HAD-like
[  50] AABAABB8BBBBBBABCABAAA9AEAADCIFC99ADCABBBBC9DDAABDDDFBGJEHJKFCBCE7FK FKIEbIEINNMHHHVNNKL-KRDDRXKKKKKNTWVWZcrmKKFNIJHJHIIGQMLIIHBCOJKFROQSQVIBEFFEDECBCDHGFEGDMMKKCJGH856IIFIKKEKJHDDDDDDDDDDDDDDFHHIHJHJJHGKILLEGFFHKEIEHHHHFDEFFEEEEEEGGFHHHHGEEEEEEEEEEEEHGMFEFECDFKJJJJJIIJGJKJJIJIJJJJKJJICGGJJFICCCCCBGKGGFFFFFFFFFFGFDGFFGGDCEABBAFCBCGEDDCBDDEEFCECEFEEBBBBDCCGGGHIHGHHGGBABBBBBBCCBABDDECCCFCDBHLFPRKKKKJKKPIPGKJJKNOMIJIHDHHJHGGHKLGGIFEHJJFFDGFGEKGHIFIFFFFKMSRTIGIQMMRMIIJJIJJHJJI5OMRMOVPTLLHDQMMJIILMNLPQSPDEFJMOKIKJHJOIIIIIIIIKGGFFIKJDDEDEDDDCD99CBBDBCDCBBCCCFFDGBFGNGFKSOMXSOPVQUPNOPPQQTYPPPPHOaPcWbaZEKROOONJMJXMPKVUJONKMHKOIJKKJJJJHIFPRJHKIIJKKKHIJJJHEIJJIGHMHIJJMJOSILDCDCCDDEDDBCACCCCCCCCBEDDLLTTSJOMMKQOPRQQQQKPPRRRPOOOQPRRE4EIJFLFDAEEEPONPJQOPOOMPNONPP-OPOQPNNPOPONPOOPOOOTWVNQNOMPOPPOPPOPPNPPPPOQNOOMNNNL9QNONOOONOOOOCDFKHHGHGKMLLLLSNSJHIMGJFHHGFHGGHQRPOTNOHJKTMVVVVVUSRQZbXWQOOOGFFFFFFFFFNQPSMMMMMPTRVUMOOONOOKLKIIIIFFIEIIDFHG87768668A8C7877A-77A87887776A9867888HEDFGGCGGGHGDF USFGYcT4*ogGZafopmgjuvow*smddZYabefcZcYZXZYfefjhjwxy**jvoehjilhcaYZXIWYUZYXYhHZgSghfXiagdl*bpbjcYWVVVUWvn*CY***s*o*ypdbgZlth**Z*c**z7*x*VidU*ch*bVmdeMvgN*g*lgpWv*WefeW*Ya*kfchfeik*khfbm****q**no**lom * b.43 Reductase/isomerase/elongation factor common domain
[  51] 23-1313356667567-2433-13633A73544-1---211114U2A775jnF-311C525343--YB Uz*5L3444442336A89A-9H22CE888885PFGH6EQK9F6OFLA47666DFM74822ABA6KGOQUU522224221131611511yv*s1X5441-ET6Ie*i*Dt11111112212222432546533294LTSKS343fBQJJHGKD79665588469D4dKOYI343343353333DA846723A3A77777877366997645CC687884755947222233AK243333333344463333342232233432222222222222233334324553225557655758522223222222223222222222945BDDDCGFGI6G592A86BB796E11D542433743534553237121g3*ECCK33233D9UNK7649989A44444444449-HFFEGCGJFED3EDD9G9FDGBEJ65BGI87AA8BCB59999999997CC937A42211111211225333447453553212259AHD83A84BUMNINODCGGEHIHRGFHG8FTJTDEH755CDFFFF66GBHEMG66K9B79832222222A6CEG8HM5C53623895553FNC87HO43CFCGo*5G224313333231212212213322444654OEJNHMH5MGDGIHHIIHJEIJHNEHN1-3F869121111787C4965567576863165565765655765555559AA8A679785967688899A9887555763532B77777767778223I555565666A9M8B454645433224447DEC8E66553DKHHIHEGKLFGEEDFHIH3444444445565AAAAAA89B89JFONTNNIIJ98783357LLFFON34433333A4311112-2222252223223234223667A6667456k8J JIBAdZr3sKUGPJUgZpbgfcPpikaPPPOSUNTRUSPRMLPPLTZWVjqw*wVfvjZXdgKHBHLHDCIKCDCQP8ZQNFFFDHMGHaiTZXhlNLNMKMOafk2Y************************b*****************************************yNdeX*PMQdY****b**PZrwhyt * b.68 6-bladed beta-propeller
[  52] 11111111111111211222112214422211-21222232222112113233112-22221321--- 67E2733334432365767-682266666666766665874635C75676637765452298B56389A8211112111111634444437325333113334442433222222222222223222222222326555434362321312322433222222322222222131222232233332323446555555455545554758877556444464444444454344444444444443444445233443434423445424332343344434343333333333333344444443334342223333334233323333333232222232224322251-535552244442333221275A44433444544444544343444444444443414444545445435558656655574456665765556774444444433444854333233332222322333333233233333655553333455545543444555455554556447673355646555557654545543374534444435536446523355645A962767577654A98AB54522222222223-1222212-2222444795464666675666566855686888889313653722122288886887C77798687-68788887677898878877988756787777777777787779777788742756666556565332633333666655866555555766556555344454465654668666578665648753334333333866658558765556557576555444433522123223332322352232323-323233333332233333323222222222423 8847**W-I594Zc*PTMNRORSQVROWWSSQTONMIKKPGOQTRRRJSSRQWNMNVMQMQNQLMEIG8OKELEPIHCKLEMMMMKRRNUkTTYZeXXYWMXX***4*XJ**********************U*****************************************vHQKG*ECAKF****M*c47AJDDD * g.39 Glucocorticoid receptor-like (DNA-binding domain)
[  53] 11222-12444444342223222134433322112111111111212112333111111112222-24 BDO4A23422243465455-55555665565556665575466645434443556234334445547986411111113322647756BA8C27775--46359D8A87322222234344445544544434B4877DE44366968A7766666665666567C98A8554445455456C994433166766666667866667A65978666756797554444457843333333333333343333334344333334444444423343333333343333333333333334444444444444423333333383484545556555595666555847236546668865557776666313A8R9AAB67668B9DBEC96B99A777777777778-BBCBCBB96D72E887EEBECC697789A646A9995677777777769987D7733333333222233345444334433332265B6463335999A8967888BB89AAAAAABC89887438777566487857468849767655555557798D6994435775BA6673ABC7C7878HIEHPP78255534444655455555445554499666969797857AAAA9A89999888898B3-5A89B12-22288797667777888878-77877787777878878877779866579777777777777776667546673777777777777347A43422666689A5544455646664555577777786766766556555544545555---------55666777776766699A7877777555522C4AAAAAA54465465663-------------------------34532232228ID6 743344*1SBB-CDE74743656565667555545436563656553446687G4644463575435435435444444411244688834441353323263DDD2Q*-*****************************************************************AHIG*GC9ICQNUW5LMr*****n * b.36 PDZ domain-like
[  54] 334---133222333--71121117--91A42--45521-112B*17r13**Q2--1332-1-14-2- NEo2*-24343121B5555-5533B7545557898AEBKF6HDXCJG4AC72AG9-2B11JJ99TEKu**963335GH4-355113-1*y**1W881--Is3HN*Xi5r--------------232-521-2262CEEBD21-e2A773998331222252236177BLB2233222333326F778KM2547A9B9BCCC4AFAGEE5ICB77A9J4657345EDEBD5M*1443133133444333-112B63343334474322882362224253337ACA611DDDCBEFCDFF68878457667864883327774M58955556566477k6555jlJV7o41635528AF56372--33-S11-81VAAB311111453412113226222212222123-4454364576218558877AC84731345453255477C2222222223233-13---1-111----1212224311221-1--1-DD2533324CBCDECD9997BBCBEEGD8CHGH2956-1678638326424731291321232-2132212245349255242145111-58942392373B7bb262221212212222-11-1122-3351-72371*F2L38C77776756655E72B47D--34432---1-1374432158B3533544-74543334457335658534875786429-2-2-123111122411143441-488867768966-1-4-----23-143Z35636223311--341-43623352223r54572458123123676----------5779AABBA894CEABPOMNKMML8989-122QR88HC-111-1212-2--------2--Y-111-3--6-11-3-473I8FDK1rP9 WKCHpp*1xGQDRSSeYvZrklV*rzqOOIIOIJINMJMHJIHGHKZadn****jihfUXVVHDEDHK9F7BJEHFI9HGFBAEEJIFGNaUYSbcCFDEFbKeVY7X*q**********************T*********************************y**x*****Eb*O*GHIVZ****k**cjjughm * b.18 Galactose-binding domain-like
[  55] 222321B9HIJJIJHD3C54-215D55B8DC541645344445742554BCFEB7988BAB9975134 Yd*4x335444424BCBFF-FB22FEFEFFF7B889HDRGCIOPFSD46843DDK737--NKG9ZCTabUH55556541364E69987pl*x4lAB41-El6DE*UnE*666666667788798DAACAA9DC9CDDDIG331Q8ILJOIIG57998798997DBERUcJ3A35443A446555544BA894B888888AD6898ABABDFFAB87A37A9544C9BCABF*23354556553335534242G3736724434DD44565454437674347658545DCCC9ACDCDB66765666776453886645552I86FA5557565655d9AA5BEEXDU5398987CCD7C6K98A88GJ375HAiNFFD57566HJMIKND89GBBF998888979AB-LJGHIHGIGMB7KIIKPOPRQMLK8DDDD98CCDAB678BBBBBBBBDDD9CA5D3334433311114424364434344322356EABABCBAAbWXVVXPPPPJNNVWXWWVEWWUTJNOL46HDKGCI99AFFDLD8CEHGBDH76898777EEIE9FELFG7CBC8NCCBB7MORFHKKLNMLRMXfFK5C56756454636544453374898GFFH7C9UGAMB8JAACE9ADEDJ9FABF8BG4-6ICAC421443HIBGBH8GMNJGJKJJH-IHHIHHIJIHKIJJIGJJCHJFGEEGHGJGGFFGGGGGEGEGDEBBBBCCE93ECFEFEECEDFD359A57457CCBCF9OAH88759765555556A99A896A455GVHHJGJJINDJHIK9HIF5684575468BFHRCDDEDNJIMRJJYYbXZMPKCABA35A4DD77684333222283632111--2315211113332421113A7678888B8xOA CI69pkf2aCGHNUf*x**********gfolhiumkahchkjhddb****************eUfYSSCVUYZQTYPCTVPYYXYWSNOs*yx***SUWXW*aos*5bxw*******ysznp*p**v*t***G***otro*s***hztjm*ld*n*z**p**q**tb*m**qp*aOSXI*KJKXi*******LMhgigd * a.102 alpha/alpha toroid
[  56] 77AB77CCCCCCDCDC99ABBAADGCCDBDDDDCCFEGFFFFFDECFEDDFEFFEDEFECF8AAG599 HOWALABBEFGA9ADDDDD-DC99GODDDDDEKFFFFJRLBLEJPHEDBDCCICDBAC77HIJCMEJJPKGA999A98AAFBCIBEBBRRXJ8PHG5--JWMHOWcVER333333333333337DEFEHDCEGFEBDDBCCCBDIQJJFEECFEFFCBDCDBFFAFHHFHBCBBBBBCBBBBD9BBBC9CFDGJJKJKKIIFKILIJHIIJJJIJLLFEGGEGCGEEEEDOJAABBABAAAACCAE8999BAI859AA98585CD999997A797988988C8999999999999A989BBAABABAABBAB989999999CGNIIJLMLJLMLHHHGMGGEIIHJEIAADGFIHPMENEAEGJKGGIDCHLMFAMKKNBB9AAEKfUWHHFNMMONHHIIGIIHIIT-LIPIIRKRNaI8aMMPRUTbXXRUUMLPINUOONOQNQTIIIIIIIILLLKHRJN88A888888833333333333333377779JJYKHPcZMSfaadZfVPQQPYXjeVUUVKSkUiUdfUBEPOQRRNHIQNZNiRKOTMKMNOKDGABBBBGGHLPbGIOENHNKEMRMLJDROUNMLMJPLLNLVjIFJGHEEFFFFDE7D7777787FFFGJEESSCQNPZGRSVRSQSSUdhXUUXQTaXVQV9-DGLDJ532555LPHEHOILUUOLQMQQL1UMLNPQPMLQVSPKMLLLRQSRFEJJIHLGJIKHIIIIIIIJKNHKJOOPOG9LPNOOPONOPON45AHABABAIFEHGEXKVHGIFHECCDCCEEDEJKMMLIOHPKOOYWXWXYacWbacaVSTSDCCBCCBCCOPRUbJKJKKbXfUUNLQNPNMLMMFFFG89GEOOIIJI34433333G65212-4-225252122226214311196AA998999AHDG IGABSNL8xiNINOPIPONWONNTVRQKJHJJILOMKLJLLLLLLNMMNTSZsaLQOLLKKJHKMIJMAJKKJMINNCJLKHHJLIJLMNiQPTLaORQJIMIVWgBP*q*muspmZXYjjdhs**X*Z**v4*q*XdcQxhbmdTcbiWoYSyXuWdoad*V**XbrWm*WXtUOQRS*POSLL*g**Pv*PSjWaWh * d.79 Bacillus chorismate mutase-like
[  57] --------------1---------22212113111---1211122121-2224-------------11 1111213111121211133-311112332331111221221111--11132-221111111111-12112-11111111111-11111222213321--11111121211111111111111111121311121112211111411311112--1111111121112322111112221111111--1112111111111111111111M22121111112111222222-11111111111111111111111111111111221111111111111111111121111111111111111111111111111111111111112211111111111111111111111111112211111111111111111-222213112111111211111111111111111-1121111122211111111121111112111222211112222222211111111111---------111111111111121211111113222482222532222333155542322323261233231222411112211111221111111112121111221111112211122221121111113511111111111111132221232111111221111111121431321212331121312--11111------I91336HCGGDCCDADB-FABIA5AEDFG9DAACAA8FBA448HIG7DEEEFHFGEEFEEDA54477A81-ACCCBCAACBBB--11111111121122111111112121111223332314112127877142513352244411111111111112-111122121321313222333331-1122111111111111111111---111111111111111111111111111111211 EDFH*yr-*WP-RNeLNLMKLMIJKIJJJIMFKHKJILGJGJJHIJKHOQUVVZGLRNKMLMEIIJHI3IFIIIIKJCJKHEJJLILLMNdPNRPMLJLLDKIllo2********************************************************************6WZN*PPMRV****O**SF***** * b.7 C2 domain-like
[  58] 66335444555555486544675889985C596368A6A7A8BBE9A75BA993769789A4434213 KUN6*DATOOP846RIDFF-FV22HgFFFFFAWFIMzdlnDmq*otZ4TZVElkm77K--vpPG*a****WTIJIeeVE7qWD35522SLQH2D872114oAJ9WKl7L22222222222222853IHFECQe66FKLAA4BDn6jBDUAEY4499331131991ERYe922-212122322ED933EE4eIMjmmjmfgoXfvmakgWUXaOUbdoFNLPNHGcUSXaQVqEOHHHFGIHILMNFHB88MKwMQ7SXBLMHQbhQMbeKMEXZDXVbXNQVTRQPNKQQOTRTQVRRTRTYZPPXaTOOSOPMPIFISLQNNjIhtfYYegYZabRPr*rJFKGeDFJ76gvAAcgobGCPHARHOOJ379B5B*ZcT4aQ5qQHeScPGEKPGCNEDCCCCEDCEc-YTUNYnZVMxO6*Zbkuuv****qNTPJVONcFMGCNSOEEEEEEEENQMBBUUg555555554444749935D764663G3FF3DPQN4IMHBTYfjsjaXHGFBYZcmaMPNETftuKMTS14QJNIIOPDoSkIqdBDE8799CEEFBDB7AIDEO7BKTKE9DGADNHBFF8HULYCAX7LEGDHPOB8844341412511411111114654BCANSXOIHJCNBKEOghUIHCMCILBLEJI9J--8L79K------YggtEaSXplaWgZjbX4iXWdWliaWkpggVaVXaTgoegbx*sUVPORRTQVRRRWPNUvNLXRQSSI1cVVZXWXRVZVZ--eAABA8ADFDE22VKbCBCJCFFFCACUHMAB7BCFC9858XTMMSVSYNVDXVSPBWTK5444454445LOPWOYNRYaUHTVOBMKKKMGHISEEG2-N8CBDDCA---21221G3J----3-11--2-----11--1----7MC866C8765W59 2122211-721123112323332112443211133322322224222421232312332323311112121121311-1222231211125323343342122223126-Plups*dPQNKTaR**HrP**l8*c*IUNKbQUiXEUSNOVIL*SZRQl69BOHABAM9BaCI94321-F---32835D2732253145 * a.35 lambda repressor-like DNA-binding domains
[  59] 444377BBEEEEEED954344428A5566389556556444443532376666366789666663-66 FLSEbKGGEEFJLEMLKKL-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-KMKNLMMLKMKOKLLLLLRVYSQPPNOPNPORPQPPPOOPOOOPKJKKKKMI9NKJJKKJJKJKJ65CODDDDEKLLMKScMNGJHJFGDDDDCCFGHQQORQIJHGKRPlmomShZagUUSSOZWWFGEDEGGCGJHKLQPQQRQVUORTQSMNPNOHIIFEFEA9EBHHFFFE4444445396722229-224453333445737311175676778878FBC FF55PSN1oKD4IJMJOKOQPQMRNTPKLMLJKHHFIKJKMJKNMMLMMTRUYRHLMNLLKMKFGKHJCGJFHGELLCJLIEGHHEEFHMTHOVMOJLLJLKQVXT2O*VlVbXlXcOOQOSQLedOxH**n-sW*JRMNUOUhTNONOKZRPaMjOMYVs*MjNSKkMO*eQZPPWbQ*OOOXWqXc*LudXVaRPQX * b.84 Barrel-sandwich hybrid
[  60] 86BD8AHFGGGGFFGH8GFGFEEJGAAFDBHGECCFGIHJJJIEECFFFHPJLDCFBCE6BA8994EG EGREbCADCBDBA9KMKHH-HO99KNHHHHHFPMOONKcaDPKNJJFGDFEAMQNCDF88QKQBWNbRVMIBAAAD9A78DBGGDEECHGJG6J774338FGIGLDJCE44444444445555ACBDCEDAABGDGIIKK878OINIMNGHJDFCCBBAADBHEDEQPRLB99BCECACB9CJBECB7AAFFNEDFDFFGGEFGKDGGGLLLIJGHHHIGKMFGABBBB9WSDDDCDCCDCCDDDCCDEGDEDA6ACCDE8B7GGBBCCCAC9969999998677D998998A89888A99888989A8889B887779888BRBGI999BBCAFADFDHHACCCDAC75D8AFCONHGICBLDCBBBA589FDKPIIPBAABCHLeRVJHILJMKNFFFFFFFFFFJ-LLOKNULJLeKBNOQMMQQPPQNSIOFHGHFNIKIIKHJDCDDDDDDHEFEFGKKAA99A99999445555556555555AAAAAILME8GRKMOGHIJHIIFGGGGFHaJKJLFEILQQYYS9EIJEMPKKJRLKMVREEJHFFIKECDDDEEDMIHSKIBObOFGUEDIQIHK9HGGFKBJJGRQSQSdOSDAADBCCCCEA8C8888888DEEEEGFJHFKLGIFKILJMHHKILKJIIKKKJLLKIA38GOOI453444MLLKIKGNNPONOPPNN-ONNNOPMNONOOOKNNNNOJNKJJLVIMKLLMMNMNNNMNLLLKLKMNNLNFAGHIIHHIIJHHH67CFBABBBJLLKIKYNKBCBGEI8AAAAABBCIIIJIGJDCDJIVTRTPURTPQMPNLWXTEFGEFGGCFIFHGKHHHHHIJJKJKJKNJNNIIIBCCC9BI7IIFFIH2322222294311111-1111113222111311222656568A8AABKAF BB37NNV1*SUHPPbVOTOVaVXeWcZQRPUVRSUTSPNQQQRPPONSLSUWYiMQRQORRROIKHIHDIHGJHHKL6KKJHHHIIGIJNaLOUNTMMNONULSWS3U*j*kmouowVZeXdhd**T*X***8*m*TZbZtVcwaSdZSWyYQvXlfd*fx*h*hkSxQV*mfnSOYfV*RQNVSwWqzTodTamqfeZ * d.142 ATP-grasp
[  61] CCC9DBDFHIIHHHEFDBCCCBBBCEFD9ACCCABBDABBBBCBACBC9DFFEAHFDJIJFCBCB9BB GHGGKDDEDDDFFEEEEEE-EGDDFDFFFFFFEFEEGGKLDDDGDGFEFDEDHFIHGFCCHHHDFDHHIGCDCDDDDDDCEGGHHFFGJKGGCGEFE69FEEDEEEGGFFEEEEEEEEEEEEEGDCDDCDDDDGDHIIIHFFEKGLLIIHHHGGIHFGFEFGIFIGJHHJGGGGFGGGFGGGGJFHHGFGHIIPPPOOOPQMPQQPPQLIJJKJPPPIGHJGIKIJJIHHKMIJJJJJJJJJJJJJHIHHJJJEJFHJFJFFENOIIHHGGGFHGGGHGGGGFFFHGGEFFEEDEEEFEHHGGGHGGHGGGIGIHFFGHHHEGLELJLLLLPKMGMHHKHHGGGFOGHFGHEGFFHGHIGGGEHGHHIGIFHFEJEEEEABACBFDHGEDDEEFEGECCCCCCCBCCD5HGGGGGGGCGFDGEEGIHEFHFFEFFEECFEEDECEDDEFFFFFFFFFDDEDGEGCBECCBBBCBBBAABBCACAABAABCBCEDDCEDCFHFGEGFFFIFEDDDDEFGFDDDDDDFEDFEFHDEEFDEFDFEDDDHFEFGGGHEFFGEDCCDCCHEEEFFKHFEKFFFGFGEEGEJIKIIHVHJIIGIGJGLGDACGCBCBADDDDDDDDCCCEFGEJJIJEIFIJJHHHHGGFFEEFEDDEGDGFEFIG6FFHFIEDCFFFJIJGKJGJJJHJKKKJJ-JJJJKKJJJJJKJJJJJJKMLLHIHHIJIIIIJJIIIIIJIIIJIJHHHHJFEIIIIIIIIIIIIEEHIEEEEEIHIHGFJGKHHHIHIHIHIHHIHIHHHHHIHFHIGFFFIFFIFHFFFFGEHHJHGHGHHHHGGHGHKHHHHHIHHHGHHHHGHIGGHGGGGFFGFIIKKJJB99A9AAAGHHDDCCD-HDFEEFEDDDCGECEFCCCFGIGFFFFFFCJGG QQKKcYP1*MMHMLRPPUSTYWTUZVVVTTTSTVVRSTPRPQTRURRURTWWVXWTXmRPRQPPPNPPGQPNTOQSRHUVOMPRTRQORRhPPRQRNOMOMVSTYbASomsfvcihqXUSUPbV*zRyT**i8tn*RZVUsWbnYPXWUSgQRvZicXeSg*QWUZVcSWzXnZVRSUS*WRWQSjZx*WtcZShkabS * d.104 Class II aaRS and biotin synthetases
[  62] 33222336644442542232222316636544353345576B33744A16B6C334335446652213 9JV-t556789233djfJI-Jz22czJHJJJU*z**nh**2aAhCJ782543KGE225--IFL1OFNTeP8-------21517335424313-62----3M4CCXCH4B1111111--1----474122522236666A4111B7QCGCDB66766679745652NOLUC5225544335339472212-447EEEEEFCH8GEFHDCFE88AABGH465BD73588986BE6CBBAABAABBBCAB5664278324424327884334554444475333267765455555555555444333332444386632366644277454445434522D772352313225332254424211143323-7BF27XNNG15334ABaOX78ALFCLC4487377687F-AEDABHEKCeM1NMHKKIFLQJPLEGMJCKOE8557HAIAAAAAAAABB8457B64444544425453534434334334544418v*H5CLK9NVTXfXVKGHHGKKaJLLLLDKpSmITPR34HHI9GKDAPLJCcJBFCBCCEM64432333675CBG6B7177776AB5563788789C38E9DCPT47354221131232254544251133377BA8C7EN5DA5DMJJHJBIJGGGEFMEGIS--2A32A------978F6797665865687-7898756857657867889AECIBEF67576877768867567B45466553-533543333534--2633222CDCD89B9G766856365246224MMKKI9A376DEYcaYJQRQJHMLMGIKI3231232324997EBCABCJDCFFKIHILIG8996223--4-883355111111113-2----1--2-----111---11----42132121211G-6 BACAteF2*MKBcamdfnknlpcultnUVORPTNRPcaTbSZbRMQhbnvz***oejabVXXKGJIHG7JCDJKIEA8CBIFDHGHGHIVoMfwbWOPLKMMNdXe4X*l**********************K************v*************Yi*lhmwU*Wtqp*oVPspf*aVUjf****j**ncpumyV * d.17 Cystatin-like
[  63] 88758769D887GDAA589877A98BI9CEIHE7B575356475GDAG85DGE56988A665438596 97F5JD9BCCA997GJIHH-HG44HKIHHIHGGMKNJBLK8FGHD99A9647C9D797338AIFA8ICKHAA766FCB43B9332635JCDI6B787-1C6558D8HF33322223322333337A4A97B5668DKL**667G7n******OQDE988577gl8****G367557557576747MN326AF5BBBAB8CDABDD9AC8BAA68ABEDHAA8D8B65578FBD55666556666556765659667DG888D57888BD668755655676A5879887A9A789B77687889965777876559775556FC88C888AAA9C99D6FE769699G66AEF9BPNLAFJ59CCDC8B375C7EGBDE6CD7PA8MGNBACKFDFL5555555455G-DCBBHOEEB975GAAIRDJGE9LH8F57976ECP9E488DCDDDDDD97856ABB432223333433222222322322223343B7EB7CCA7CEADJFAQ89AAFFDJBBCBANFUVBGGE57HHCBBCFBJNHJIAH7D696CCAAA56757666MEB5ICCB76B6N4BA838BB8B9E7DCD9CPu9K6669446448766769697775677BB979AE9B87977D9A7679A88D87889774-6C67C243333BC678DECTWIEFHGSB-SBEGFEGDDKUEJCDDBCDACCA98CAEDABBB9BCCCEECBCFPyDMFFE62B998BAA9AECC22B756545BD7CD5B6665797B47956C655767987886ABM8AC9A9BGMRIBDHjBC6775777675*8BQ88898*A89A89A8AA9AA9987844U75555564C773333986A5E65-45435644444652133326B458445444955 DA89YLI3SC76FCNINJHJMGJIPIKHHNHHKLOKJKEMHLNKHMIOIPPMOSIMKNGLJFDECMCC4EDEECBBD5DCDDDDDIDGGBPGNEGMGFEBFLBSKLBJOA**********************J************s*************q**y***********ZCGGF*MGKEGaMLqLdPFENbPHA * c.52 Restriction endonuclease-like
[  64] 332243664333543425565439E7698E6ANJA754A68769c6AIPD**l313263533228123 DPl4l234654532944AA-A666D8A8BAA589995DHBAH4P5G556994CG773332E9C8U4FOLF855555652245A65723A8ZX39423227nH89geR5i354444534445568CAHCH888E677CCBC222H5*y*opmaLMHHDA9ECFQZab****9C998B9C8A899773448-97EBBDBCGBA5DEECCFD9GGCEDAC956C9986657A6DY35477766764457687785825275231279944354333725453443A7A5543554455554432332435322235552225554E43KG4444565A5BA9872342M4A435H443A8A3453524554915483MPGGM3J84AAGIGGF57B99LF444444554461HIMNSGKDBBA2AHGAPVLPNTGECBD9GF9H879BI8F777777776974EIS83354444533BB9833998865654433577AA64AA97ML99CBBLFKKJ88AINOQM9GEGF68BB-4A5VD57446C49UC7IE687E8525C563A554576OHBAA3A367E644-5I87FCW9A8HE8N*A9545364348221-2111-2474176964769Bb7557I74688B4B768577AC69D313D57711111168ER7AB9NKBBA98CB-K9BED89CBDL9H9A8DBB795LRMKGCD7AC9C9BD89999AK965B99773EJJHHJKDILJJ33E444444A76784S6F5263124314-2243567C788337SQGFJFAJAE97C884HTH322222222544394555598868B9DKBKIAADDDCF11X3AA77BB---2121-945--3----112-31---1-4-3----67754828864P7G *XBEZfl1*QQACJReKVifkrTtiucEEEGIIE98CEEGDBECDDmkPist****RdQQTQ699A892689C677A78BA978AH8BFOmSKJUZFBC98XEGPh3T********************y***B******y*****k**po*tu******w*****cj*aj*n**TCWUO*NQNlN****X**UH****j * b.80 Single-stranded right-handed beta-helix
[  65] 22--122354563451211221111112241232-11-1----11-23124322111---12-1-1-1 8BK-F2-1--111-31122-251116111112345332A6-474311-41-1635--6--633173653722---644-11141-111454--3-1----3393BE7132------1-21-222--G3-322F126AA99---B5L6833724312-241225316CJIH-2-21111-12-433121-1-1-33334313123222221321124112-41-4-111--212121--1-11332-1---113311331122422--32---12---2-1-1---222---11-------3-11-121123-224---543-1-1453325124-1-1111111-324--2251-3371121121211-14231I544622-1333E845126546A24252343329122921631C64-534A66567453A741344852225237777777772243C33--11----1-234-12134512222-----72D-145Q4283452434434AA4694855699A6C38-211C6542125228A1644-322611-----1156247B2652-3432-12-624165B13-2416F25-2-2321111132123431431-23-123371B4-2-231F--491422446-3343--12232-11---33261514447476544-4547966654457434445-31342225736443544454554222533322-255666567768--1211111232412D2B1----1111-----133-11113-27834134341-565514112-211211-1248232432775--523222421113-3--E-111154-----1-1-2-1---1-1-1-------1211--112----1-1---1642 BC14AL*1iNGCQDiVh*ojfcijgdmfgcYTZYlRUURUMUWWcciqTVvphsYdgfVZVaNDDDDH49B7BEDBB7ACBDFLGGKFEZdWhng*kebwK*ODPL1ScU**********************k*********************************z*******hAHT9gAECCCbXcyjmQRZIfVlG * b.121 Nucleoplasmin-like/VP (viral coat and capsid proteins)
[  66] 662244BDDCEEDFDB6598865GIBDE649I111353232231221122563-76555557993133 FPcJrGFNCCHFEDk*zdd-dvIIz*fdfffq****m***AxP*AABI7777FGHEDJ55RSjBVVhhXdO455545526B7Q96888LNKJ6ICB71-BKHHJWILIJ77999977788888CDDDEFCADEHCPSSaa445HISGHLHHGFEEEACACABFEEGIIMDBABBABBBBBACHHKFF666HFLJKJKLEHIEKKMFHGHNOOKKHKGGTNPI979889B9TC988998868A9988A7668B81554654342876746465554668665645455544445545544476774455456466544444558DAAB966777899AA9CC8898BDC87I99D8EEBFEGAKE786K68A6W8CaTTk46757FDzjmIGHmengaHJIKIGHEHJM1GFSFHbGPQYm4PJJINHPQOTUQOSOXQKOUJONMJPb77777777KBBA7UWM554444554435768868977877843787VXuR6H*pWqSXYXhSNMNNMSSZeVUVTHWdV*p**uABXZMTSPQQlYghp*GFP9655LG6676666688bUTG*RU968669B7965MKLDRBH8BQOMPWbED556665555555655555557677876JH7JODPERNGNMONOJMTNMLLPMQPKQR418BDA8223222DCIF8FBEGFEEECHGF-GHFHCCDFEHFGFCDFCDIGDEACDBBDECBCECECBCBEABCGAFABBBE74BBBBBBBBBBBD447LDECDCHIIJ7LVBCA89A79778759BB8TURRTGNLLIN9aaYdLXTRRQQOOLJJM6767667677ABANCCCCCINDHGLNKNLQOJKLCBBB55H8KKHHJJ33343443G531-----523--------5-------5B658655666F7D 7637RON2oLG7tmRPVSJWMSOYJZSNMPNOMLLMNOKNQJMQQRQNNTQPdXNOJJHHJIG68796485878898388A997A9444IUGVNLJCECDFKOaRS-O*U*fgdjmjVSUTUUSylS*S**u-*m*NTTXgVZhXOWSTNeMOvScbYtVmzNqbSIYLLhcakXQTQL*PPSWZzit*SqjhjiUOSw * c.14 ClpP/crotonase
[  67] 11--1-1---------------------11------11-----12--11121--------------1- fa*-1--------2---11-11----------------211-11--------2---1---1---1----------211-----36D77****-*PP5--**d*q*Z*r*9887778GHIIIMM6AC8ECE69DUL----------H7684425421264743FA3eIaA334222149322313212-1B-----111------11-1-111--1---1--1---------22-----1-1-1111--11---1--1----------2----1--1----------1--11----------------------------------1-----------1-------1---2---1--112--4--------HD*58****APFCOREvarUdQqTXdUEGEIFGKGJHT-TPNPPMbbJOJ1IPPGBBCGECJLcO*xfADeBADF676YUYYYYYYGaXfA6oJGFPSPHHH218689BF88F86888953363h**rUUphcU******qkjlc***wwzytQp*x*l*q*37cdeIbRKL*PIJaGL*DPgHdYGNmVUaXVcGHIVOIMGCM4948988A6JHDIIIALINGCBEWbC6PARB6C789D3BBDCCD9ACFI59HIHTR7*M**n**9z****pvv***vxuw*v**--7DLKH2-1222*hOQTrVf***mzy*pi-*ilwtmtnuy*xwjghlieptqfhTYlqockpptprtqfudlmkaYWdXZbA1impoquqjonqm22CLBCBB9ECDDDQWITbUWIOGDJPGBJKNShfhneHsBGfs*v*ovo*rwWn*rdTlde111112111DVdgmSTUSTskbgg**********NMLM-166DD77FH1111111-41--------------------------2-1-21-121R*Dp 1111315-6-221-3424-2541252-22111211-1312212--155254223222-3132323231-1341-22332314222-1-313123151-221-3261-344M43552A241133274283Ot74664132232334266223324-252M3234C262254-24I85321N2123296Hl2O732*1231 * f.4 Transmembrane beta-barrels
[  68] 76-4--CKPLNOQMMF2185774QH66842BC54A1--66664BB9DD88978----1113877---3 6BD9*B9877AJBG***jj-i*GG**jiijil********5*h*734B6I94JDQDEN11sdP8*f*ql*J4343444-6FEN32432CB9A-C331--5J554p576611111111111111256568536785IHHHI555*9INK8MNT2233443433633AWJwA433333353333A77CC--3FAjGGIGJOENIHMJNSF89LLOWGHVCLFKE77444444y63888888888888886765631213212121172222121333444223325218612211111111222222222312212212222224---B3333C33142a3BB11213-A22B62C3IFA4C5-1F81115-21C5ATFFQ11111BAwc*A68khjcY46674465658-JHQJIVFGFNQ-FFFKABCC9FRBIXAI9GIQAEEEFIQ44444444D9336KEG----------111111111111111----4GLjH1CTRGPRacbcftRZZNOMUc****RqkSsku*h56NNWGLLKHkKRVjg54N3144K7332222286ESHL7wXQGEHGBJDBBB2DFD8E99ACDFFD*hCG33321333332141-11-111442743EI48EAE8B99AABBBPEEAAABF9DDBFG--16DC4------K7ZFA87AAAMAKKCBA-8BBBAABABC9BDA99AAA98CQD**897899B999A889899F67788871-9AABCB977ACA--1746685BAAB6Ef7O333263133323334EEFLE6G9BAVFcgYd*plnKVSYVBgV*7444454543678KCDDDDBD8BC98A67666665444--63DD666632222222411--------------------------2--------2I25 I667dhG-dHAAKKo***x********hiimop***toromuohhf*n******yj**hXVVL9C9897DA8A8CCB8AAABBBHCFEEp*X*ZVRA8B8EDbdcd3P*X*l*j*esSQOPTYR*vNwS**n9ug*VVSVdRTiUKTTPMsOLmRZZTkVg*R*dqooUl*YduO9EKH*CFFLIeji**qwHHmbcWn * e.23 Acetyl-CoA synthetase-like
[  69] 323331223433344223224--7A3497B8492111511114334568977633535632-11-222 1553h37333122188754-5B22A755555ABACA8965N99A5572H743455346--CHA3h66JOBL343343323223324113456-422---19245856851111111-------134544431575EAA69111R4F7C968775776663899988CFH834342248231274A34333215dQobnjQtEynomUlCHCC85syG133524BEDBEDCEL3FFHDHF9DFFFFFF35452J273543113187332221411476333365378552224212333211221145533149211112121I24D56766656663T3226886I7w34344515573133211233D11191Q444522222446A76466566633233333234-57856766A55-7335546A55466725494653466454444444453333546----2---211111112121111121-13354642FC889L6665A933457786CABC7787DABBE1298B67855H6746538A34126422222211322453E2-2-42121312184D347C9B2333CR3421121222124-2-1-----433681-97348P428468333385549636558444--234131-----bL--5MXVgeiVdfWVS-cSOcVOKdbZdReVXVXXJRNO56NWqaFRRRVUSYXYQRSRVWCGDNHQL--EDDDFECCDFFF1-14111112222C9I14-12-1-31-141-1178666254336VDFED3A9H557966DAC311111111535853333397586C85575577785552142444468111111115-13443--1--11------1------13412-121112741 LIBC**R2lEJ8FHORLMDKIJJKHKPMKOJJKFGFLHGIJFGIGJNMKRKSSQLNMQKNMNUIJFGL8OQHMGJPM8LLNORSMXJFDGQJLKHKLGJEHHHZVeCanR**********************E********************************xm****l**l8QPK*KKHUI*k**HxgTTWVSWP * b.2 Common fold of diphtheria toxin/transcription factors/cytochrome f
[  70] FF8DCEGFLMOLMLMIDCDJHFIQMQMMJFJLD8BEGDECEBFOJJITFEZRTEKGJHHFKBAAE668 GSa8WA6A9A9767FKJII-IL77KSIJJJJFRMNNJRaU6EEIG8993772GGHA9D22IJH8GJSPVNE2111321969GQB8GGARQOI5OBA51-ES8LNoIRFL54555545655555J848987476G7QKKOO777cHPNPLNLKGECDCBBCCCEIDFSSVSABB9ACAC9AAALHFDDB95EHRcZfZgcadJbZaXbZHOONIOfeZFKIPLHGHEEFDFbS8CCCABBBBCBBCBCB89BBD886A9667777888AA87746476687887776788888888888877778777887777776667779FNDQYTTTSUTTTUQAPONJIHFKRI77AB9FANMFHHMGLGBABAF9FIMJHGGFM55656DGgZfFDAJLKKJ6666665666B-NSMLSQNHJML4HKLIMMNNKKPLJQCHAMELGGGGLGN66666666DAAADEC9222223323287647938C44377311139DJQF47C9AGJFFKGMHBABBFELKGFGFDFJJMLTUO7AJPMLMDGFJFKDKGCEGDGGAG64456865A9DKNKJqUWIGICALREDH9JQMLMKOKMMLXNtpNL67346667643335456465B5BAC88BAKGPFIDLFAFABBBBFKGBA7ICHH8OM2-2CCDF11-111ABEL7DA9AAA9B9B98-AA8B99A898AC9999999EHHGC8CABBBACCBACB9CACABG897877A62EFFFFFDCFDFC334C575569CBCADXBC666C88533336676DFFEE8A69ADCJLLKGGHEMHGHHHDCG846546544HDDEIDDDDDBBDLLEHGCGCCAAB977735FPNPHKHG68649766G4622225-22322222223322322228AACDDECFDBSBF ND4AQOV-xQNHOSYQLaRZWePhVeYKKHJGLMOLMJFFBHGGJFLKPfSUwePPMTLLKMGIECED8GDBCAGJIDIFDCCB9EHLIKcNLRMdLFLIEIPVQa6J*i*fukmrpVZRSWdU*tW*Y**nBtn*TYaTlWbydUZWVQpUO*dkfYmZjMQxaVPZTSfUWt*EibO*PRRQUhac*Qs*SRXRPaT * d.157 Metallo-hydrolase/oxidoreductase
[  71] 78ABB7HGHIIIHILF8CDDCBB6A78B8BAB9B9686877667757556C799BD8A8898867287 BAM8J335667464CDDCC-CH88DNCCCCCCHHIIEEMK5FBB97555444BA953G22JLD7FHGMKH785556662364B4676475AA4B325--5C7FEPADC6111111112211111644487454D7B99GE333FCDCKFAAB76787766477E9EFCP8348344333446B878853468BBCCCCBBA9CCACBA78AA9AAAD8898F67577876D84778787777777776977867749756746AA449776544385632323233332222322222222222222232224224442224662486668695766476524437272387655B9A7655B676657452I5CECC95535498IGI57BACBE97778757677C-HGHHEGEL9LA3IBBEBBBDEAFEGC8BACCCBBAAEDD9999999989A8DHGL3332322222--111122211111143348A9DB5CIGCGKKLLMLFHHHGJJKJJKJKCHOKEGIII4CIEEFBG8BIBDFFHCEDA667EA35444447B8DD96AA9959D6BA99748656767A7FFBEGOC79736444556433333333378567A9978E8AI9B99EABAADABEBAAFCACBAG3-4GE8D221222B9FD8BA9BB99AAA9A-998BBB9A9A9A999999ADDCCE8ACAAA9AAB999AABA8AFC9BB99F84B9B9ABB8CAAA--48565557788E7I7B555757355646565999997E887CBNLHQHEFKGGIHHBGFICBAAAECCBABBC8DEDEEEFFDBFHJEJEDBDC666644E67777882111111281-1-1-1--------1-----1-1-1-47554585447927 JJGGQUsC*OHLQRUTWZYWWURXVXgRRZXSTWWVPVSTRTVTWTZXVXbcaZSWYWSURTSTQLORDPMLOQPRSJRRNPOQPLQRTQhSWbUbXSQSPfTXSgIT*Y************u*********9******y************t*********************kRUUP*TVVWY*j**X*ueorjTSd * d.153 Ntn hydrolase-like
[  72] 994744GMOOQOOOKH46F9BB6UH88B949J45444455554454454454544544554ACC6-77 9FOCx9-C446686o*rXX-XwAArrZYZZZazz**r***A*f*CAFGACA8RRPEFP44fia5Uao*xoN--------444O64644C86E4A4462-GZRQIeRVFK4444444444444456544A454645HHHNN222PAE4CE7785444776666687D76N9464444464444KGJEC222ICPKKKKKFGMGKGNFFGEOBBDIIKGGJFGMB6888888TG4DDDCCDCCDCCDCCCCBBCA4987788484888888888A88AA8997CAAA66A66666666666CCCCCCCCCCCCC888666888A58BGDDDDDEDD8F7LCDDE77639B21K79B7LKBF7G6CJ745C5788L4IlXXW999AANGdWaIIMZZeWRHJJIJJJJJHM-HHPHHYDNLUeAQPPIQPQRPUPNLYNOHINRKJLLINP55555555E8879EEK444444444422666647646644644444OOwP4GocMibQQhbdSTTTSNNhXaZaaPVrd*Tuti8ATVTNKQWUZSPjmdBCP486ANC7666664888XPQF*PWI47654D6664QOMJUEQFGLKGLenFH464446664686477677775444577LK8DKHOGHNIPKMMMNQWMLLMRLRLMNT4-8CE86222222IEOF8EGGMKKGEEFGG-KGGEEGEGEEKEGEEGEENMONLEHSFDDCCCDCDDCCCDCCDSCCCCCCE92HEJEIJJFJIII446FCGCCAKLMM8LOGO6664B5466466684MLSTMGQHICQBddaeSiTcSaMYQKTSQ8666666668ADDPDFEEEKMHOLJJOLMLLUYZ8999668EAADFGG444444445-A-------------------------76644282225J6E 741-FLE-RBA7GKGNRZRTNOQeXdSJKMOKMJMONPNQGQPNMLOOMNPSUVKLOJINLLEBFA9D2EAAEADD88CAAEEFEEA79KRDRKGKDGDCIHDTJN4NyGZSXJCMPMKIGMMJheFoE**Q2eNhNKHHTGLQMKJCNIPGIVHTUMVILRHQQHLUIKXEJXHDWaG*DAEOW****T*qJNSNOE* * c.95 Thiolase-like
[  73] 87648598888898AA69665856B778CAD7EHD898878986767659B99BBB99A9A5555-56 JHODPFDHKMJADCGILCC-CICCFOCCDCDDKGHHLMPKEQENMJHEGKHDYQTECL88NLHKRLQPVQHFEEEGEFIDBCMAABBAEFJJBKCA4--BGCDDIDQDF65555557786666ACCECCCDDDDCNOMRO788PMHGHEIHICFCBDDDFDDGDBGJGJICCCBBCCDCADCPHHCDEGBIDKGHIHJFJNDKLJHHHLDKKFIKJGFHLNKGIFFEFFEJHGHIHHHHGHHHHHHFGLKMGKEHBIJDIEEFFIGGLOIBGGJDEGEIHJHEEFFFFGHHHHHIHHHHEFGGFFFGFGFFGEKJDEDJIIFDKHLPKKKMLKMLKNMJBBEMMKDFOJFGEHEALHCBCDHHAHHIHFGCEDADHHHI89889EELJMCCFJEHGGFFEFEFEDEEN-ECFBCHGEMSC7PNNLKMOSSOMMCEDGCGHRPKMONHKBBBBBBBBLGHFKECG984443445455765567866766754569DHGB9FKKHJRSSUTPSPNPNSSMPUVUTKTQRTHIGFCEJKHKGIEEKJNJNLEEFBGBDEGAACAABAEHHDFDDHKEDDEFDBEGGDBCFDACACCEFGGFMMDH9DBA9BABBAB99AAAAAA9BA988DDMKMGAICDJCGGFFFFGJJFFFEHEJHGIG7-AGACC35-656QLMJMMLPTUSPQTSPP-SQPQRSSQVSSQQPPOPPMSPTILLJLSLNONNQNNOQPSPOROONNPPQOC8KJJJJJJGIKJK679BCCCCCBDBCCBHLJIFGKGH9DFFBFFEGCCCDCAFCBCJDIHGKFMLKGGGFFFHHMHEFFDFEEEDGIJQGGHGGKLHJLGFJJJJKLJJBBCB98DKDDEEFG77787777963--2-4-2-3-2-11112311-111-DKFDDDJEFFDKEF 7977JOJ-XDD6GGHHHOFMKMOPLLPIKJHGGHHJFFGHGGFFGFOJINPORJHHKOLLHHCGDCGEAFFEFGJFHCHFEEIEEDGHHJMGHJKPFIDIKHIKHE1CsLcQPMSWMAEB7EKERG9QBv*K1RHe8E8BJFDHB7DDC9KD8TEHBCMJUfHSLJIRFKcKWQEELRT*MKHMOsai*LtlIJPNMOK * c.72 Ribokinase-like
[  74] -------------------------------------------------------------------- ---------------------------------------------1---------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------11------------------------------------------------------ 1222--Q-1-----------------------------------------------1--------------------------------------------------*1-**********************Z*****************************n***R*imqNm*7---1G1-----------1--11-- * g.18 Complement control module/SCR domain
[  75] 5564338BAAA9AAAA67999DD7LBCJ7CDB79C99EHEJCFIFJFQNEufC65446573A852-67 BFQ5PMFDOOQJIKICFDD-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-IHHGNKMFJIIMJGHGHHDKQOXTJJJIGHHGHHHHIHGHGHFQGDHHHHHA3LKKKMKKGKLKK1287464535364HARFRBABBCB3798697ACACCCB8A69CZBRSORIQLPPJSKKNNKKB77769667BGLJOFEEFEIMIGGA98C8CB888666655L9DD999911132232D421112-------1---1--2------5797689787DD95 AA77LKF1dFK6LCNIFHGFFEGLGLKFFGEDGGHEEHEHDGGOEOKIEHKMNQEIEIGFFHDDDFCE5DDEGE9DEBBDCCDDCAIDFGMIFIHMEFEECOGNLP4FiKmZmUaTcNKKKNOKqfKgK**X6lZ*HLNKYKRZOHRQNIhJJhOQcQROjgTSHRMTKN*PQXKDNQU*RPOKRfUbtJgcNPGTMXQ * c.92 Chelatase-like
[  76] 33232133333333333342422365525456544233333347544835555333333215331245 5B93463466553566566-6755766666678666557724655444343357444534653557865455666656488785658755585844421787D595756678777768877775466865646C55996755687MMHFIIMCEHJ9999C8GCGAWRTG9AAADCCBAA9B888785456BAAA9AA9C9AAAAA9ACC888B9AAA989A899889998D7CCCCCBCBCCCCCB8AAAB9776997976777AA7797853589999988779889999999999988888888888889887778887798AC9998999B9CC898AA99966879A784A89A876757776764645669989B899BADDB898A8997BABBBBBBBBD1CDCDBBAB9DB8EFFEDDBBECCCBB897A9A9799B8888888888A99ABCBA888668884566767787677777798BB97897A8AAA9CCCCCCCCCCBCC9DCDCCABCCB999889788DAB998C9AB7ABEB9ABA78888888989E9B9AB869C6689888699A79A978FEEGNF9977778666657665766666B764577DF98D9BBFCBAECDCDCADCDCBB9AEAB7-89877872888DBBBBBCCDCCCBB9CD-DDCCCDCDCDDBDBBCCBBDCEBBACCEFEEEEEEEEFEEEEEDCDCDCCCE5DDDDDDBBCCDC77A99A9887667ABD9ABBBABBCBB898BAB889A88CAA9BADDCDDFEEBCDCDAEGF855556545BDCCBABBBBCCDBBCBBDBDD888899976A67689766668767681635346-235339533344445422354667655554998 lRNRaXV1*imAfidUTdbZdYUZWTSaVWWTaTXUUXTXRTRYXYZUURVUYWOURRVTUUcPUPRXLPQPURUNSGRRPUTURTSUVQoZTVXbWVVROYSeclBd*X********ejcm*t**k*o***A***drrl*mz**j*sge*pa*g**w*o*pfgnkP*gl*VhnfPcbp*mkbbf****V*yguYecjv * a.2 Long alpha-hairpin
[  77] 77A59AIDLKKLKLJEABFGGCBDC9976A9CB7C86DFEGFFFDCEFCDHFE9DDADDEF7CB8-33 GHUESAACDDBDDALRWJJ-JJEESXJFJJJKONNNNSnkGLMVDKJGEHCAXOXEEJ99WQVESRoTWLF6676657CEGCK8A797KINH9BDD446BFBICKEHDF77777778889999BCE7GCB8GEHFMMMGH77A7GEHFGDCHBACC787796ADAFIKIBB8A7997B7777BC9BBAA8FCEIIIIIEJHDLJHGIIFHEEEFHJEFKKCCEAGIIHGFDHCDDCCCCDCCDDDCCBEEDDC863BB49528KL66985B89B9IDB79774664668666668686844444444544446546666668JNJHUABAACBCDCFHIBB7666EEH77KAAGBBBBCFEDIEKIDIGIDAEHBNDDN88988LIkaeHDJRUYVWGHGGEEGEEGN-GHQEGVHUXSB6PCCCEEWMGEROHRGGEFJLHEINIHRKKKKKKKKMOL99MLI66666666772254544445545546666BAImDAGMJFJWSWSTUNJJJLOOSXMMMPFPNMeLVXK8EGFGJLAGDJJPTePACLGA66DC66666668ACIMMAMQDLEHDCFGFFC7OQPHPQRRLNNPNCIHO788997879876766666679ACB9HFJENBE7CCC9FGIEEEGGIDDDDJDEGDOK826HDDA666777JHJGGMHDDDHDHHHDD-DDDDDHFDDDDHEDDDDDHPVRPKFGCKHGIGIIIIIIIKIIJIBCBDDDD87IECEDEECFEDE679DABAAAGEEEC8IECAAABBAABBBB999DCCCBC6AB9AN9NKLKFKDMDDDJD9HBD6887878886BCCIGHGGHFEDFEFFAAAAABBB777755D77877B9-11-----B5422224-6447674665457445222DDABCAG9DADI9C CC-3HCG-eDG7DEIRNRNMSWLZXWZIIIHIGFKGJINHKGHHLIRPOPSVZiQOKMKNLIDEFBBD9EEGEEGHE7DECBBDEGBEFKTJNRMMKHMKHBEJLP7GfHaaYRUMMHFHHMOJdeOiJ**LAeUpONJQbOMXGDQQGJSHFbDQJLLJgoEOLOMuOIuHHZDOHIF*FJHNHaRqnKadTPWOLKF * c.36 Thiamin diphosphate-binding fold (THDP-binding)
[  78] 444342AAAAA9979929444453FLHBAAHB446443453349D6B644E994464969896632BA 7ES8f77EEFF665rniUU-W*DD*hVUVVVe****pc**7YMpFOGD7AA5SNW99F44YKT8WLdmde723332333343B712323345365441-4H5GEUOJ6O222222224333333CA6A7CAC87DCCCBE444F6SDEFEG958CB7697779B9IJGUF8754555664559786634457FEEFFECGEBEEEDBEA9887AFEF7B7BE78555555ON344444444444443544573242662324244224522322122233334553532222322222244444454444443442224442465976666657456A7886333546439334457458533255564422K4AUBCI343348GXHM967998EB8888887788B-DDIFCKFJITJ3ICAAIHJOMKKN6DCABASHC89AC7EAAAAAAAAB99697692211111111222344224233223221245W*A3EPIEENLNQQQIJMNHOOMQMOQO8LZKfHQNH46FEIEIA87DCMDQJ8FECA9D65555555576C7EGHB9D45494A46662B8B578976FEKGSX3943331222222232222222223459AB78BB8A4B7788877785687575675671-39878-1-11187G65978AA9889778-98899889A7A7D998999BCA868E5887889788978888998778868435767789777673338555548A8899C8C555234423323553HHGEG7D36387DDHFFMFI8DGCE7BCA6444444449566877777A9ABCAADABAA98A67773376IIFFJI1111111-325--1-2-1-21122---1111-----54354545448C1A D*CISbN7nLIBOLfMUYMTWcTlhgaJJJNJLMSKNMILMLNGEGWSMdaWadKMZPKGJLIFJCHFAGFFFDIFGAFFHFGEEHIJHJoJUKRVLHJHHKNYTV8b*********iqfjilk**i*c***8*y*dofe*co*jYpkeepZe*mzsquQi*VgSdUtZawemYNJSRN*OMKXj****S**RY****Z * d.129 TBP-like
[  79] 774744988696897679BDA99AB768F8FDB8CAAAAAA9ABABBBABKHE8AA65857A66718B 8HM8J97BAAB798BJCDD-DHAAEQDCDDDCGCECFMRW8EBFCF987987IJI97833EEF8EHLHJFB6555666458AK967779A9A68452443B99DB7GAA444444434444447AABCB98AAAADDDFE889FKEDFDEEC9899889998AABDGEHB8977788A8788DBB99B97BCFHHHHHGHIDHGHGHGFEFEEEHGGCEFECAADDDCDBKH899989999999999BA9AC65686787555BB77676666957676666444B99777777776763433443343344C899987777BN9EMCDCDEDCADBCEJJA777H8965DCACCEKEDC8CABCCBCA658B9FGEEJ47757JEVSTB9FFHGGEAAAAAAAA99H1ABMCARCJML83NHHHIDPPNINLJGDD9CGIHEIJECJ87888888JBB8CDBC444454444434545545555455454557FGUD9IVQJUMNONONKFFFFOOPXHIHIBLNIXPXPS8ARQMEHHGHQLNHXbDDD799AKC9BCBBBB878GGAAGPDBCFDDGFFGJ4DCECEECBCCEEDDNBH977666566945855555555977A99FEJFEAIBKGIFFEEGEFEIIFHEFFFHFF343BC99464556OEDFDGENMMLNMLMML-LLKMNMKLMLLMOKKMLKOMPNEDDGELKIHMIMMJKMHLIIMGKGFJJJJC2GGGFFGGGGFFF5559444449989ADFFI666C5945656778BHHHGHCGAACL8IIJIFLKMEJFIKFHIH8777787776CBDEHHGHHGHEGHEDIGHGGGFGAABB66AA9966662222222282211111-1-11222111112221---38822B7AAA8C86 8D77DHP6hII8FEIVTXVRSURjfgZNNNRQQLMLJMLLJLKIKMQKJTVaiqSSWOMLJJIIHIIHBHHELHJGH8HJJGGGGGFFHPSNTRORNMNLHSIafg6PdS*goSWdeXQZQTTWsgP*N**p2rd*SRRThUWfSRdRQLVOP*aWRUYTcpFVNLIfDITLTjMKLOK*MKIHMtm**VzjNRYXbaQ * c.8 The "swivelling" beta/beta/alpha domain
[  80] 55132311211-323-4-555665D2258-58---2411-122111-92-1-1-1212131---4-41 AFH7*339BDG23223311-18112V1111119888AIWVFfE*erZ1ORK8gZf22E22HEUCkBdqreCNHHHOTQ6---H112--98CB25221--2E183F4G6I-------1111111111233311731HIHED332SB97997773423344342444288C912-11113-1-1KL987KI-KEEGGHFGEDGBGHFCDGMRJJHGFGCAOS8DCBABCCABKt54444444444444452278HBC5DD5F74AJJCCBF977FIA888CBCDDBDA99AAAABAAABBA9AAAA999A99A99CC887CCCFFE8BuAAA9A99DAFDD448CBEZB873D2H85BB7B96S64AGCIL46953DFDD412212H6***63AdIcgRPRPWORRMRQl-BEkCArFZJ*2-*ttm********WbC26RTZNMNQSJQ33333333YHI36E4H----1-------22221221122221---44A882IYTJUejmlpfQMNNLcc**TRTSKVfc*QdcN15XYXe8PKNbcnSx*9DC-513FA11-------1CHM5JG376K96MN89A4968B8D77555557a2N3-113234442-----1---222--11IIS99EE1D5MABBBD58A9893678648C---3213------bYZVCZORTTTRSTTSQ-SQOTUQRRUTSSSTUPUUQoppUVCEEOOLLMNNNNNMLNLKLlMJLKJLOC-XcdddefYceef---111111323333SFYABAE8H27898BCGD------4232SCBBBCBIJVCIELEBSOP2--------4GDEXHHHHHJKFNNA8CECEEAAB3433--AB--11--76656355457----1-1--11--2221---22---CHLC78TAE9-b22 4-223361E9*134A11222453121322-23-2---3122222132-3111332314-5643-11-3-11141221-----11112-115-1143---14-1657-AoB*******VPQQX*W**L*V**s1*j*QbRO*PbgSHbSTNsIH*TfVe*9EIa*qaOlOP*dsy*254-3---11KDD*2T84167427 * c.93 Periplasmic binding protein-like I
[  81] 11-11111-----111-1-----333324321-233331111-44-133253321113222112---1 3541211111111122211-13--3111111223333345-2111-12-111112-----22-121345211111-11--111212212224-223---1147511-3----------------31121322-421111-1111-9A78444235544456445326765162211161211113------41334343353444444132112424222123211111111--------------------211--1-11121111--1-11-11---------111---11111111--------------2211-222--3-1211111111-2-1112----1-1111-1-11-21--1--------12142112-----22321--133422----------1-333331-5231-1---132324222242222--1--134111111111111132-------------------------------3221-1111-233463-111111353333134221313-211113----21-1---4-11122---------3112-4523232175112-111221133----1-1521111-----2-111111112-2562232-443422533222222622234255355--1-222-------1--31-1111111111-1111111111111111112111----1212111211121211211111111--111111111111---2---------13523---------------11111-12245-222212132212233122111-1--113234111114544511222221111111--5-11--11--------1------------11----1---1111111211111112-21 2423C4L-J97164A44544896956643112122233332223316843449833341444641122-5324-333222322334-217B3497B5338664CA8-4xK**********************D*****************************************n5lkZ*MNQE7ITJ*4tMTZv*w** * f.14 Voltage-gated potassium channels
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eDF58AEAACA9AA9A9ADA988788998AA999A667CB9CDDBD89HCCABC99A8887889BAB9A7AA8BBCDF988BFAA9BFAABB99BIGH3DgF*SjbaaTZRXbbXX*wPrc**q8tl*XWWQdXeeSRYcXPoRR*NWVTjJLKQSNZQWViKKPOHKLII*ILMHMbSkr8dTOKOKELJ * d.52 Alpha-lytic protease prodomain-like
[  83] 44352368CDDDCCD66G686768F44F9EB5B9C6589787AD98CCAAEGG88B876495349-58 GGx9RACCJJLAAADFDEE-EI99GJEEEEEGFHHIDMbaGGDIdZV99MHDXYZCEI44KGFBOEPOaPC9999A9856A8DAAA99HGOG7V893558HAGOOBkBY555555575655557AAAB9799AG9FHHWV779EADEGIDFACDDCCBBBBBDEBGGIJFACA9AA9BA99AFDB99EG9FDEIIJIJEEH9HFIFFFSJFFDHHHEBIJCJCEEEEEEDInAAABBBB9BBCCA9B8B878B8338A36563BF569B677868CAA7668555957999ABA9999844445343333439777767778EE7AHCCC9CBDBDA9D989986JCA44C99AAEFDCC9B9AAEDFD539EEmLHGI58978FDIGH879B7C99MNLKLJKKLLM-JIGIJDIINd86cWXPZZeghfbaEBCD8HPGIGGINIK88888888IGICB798443555554433222222222222244447BELBABA999JJIJJKIBBBCHHJMFFFECJJJKDGJD65EDELB9DABCFDBJ99AA879EB98997A98998AF4DCD9CEEDEFCC98CFBDC9EHKFDDFBCDIAA879AABABBBAA999999989AA88FFHEBDDCHGFDFEEFCFEEDDCDCEFDFG327997A755777MMGIGKDLLLILKJKML-LLKLNLOLLKLKMJLLMMLUTTKLLGFLLGHJKIJKLIJMJHIQIHGIIJJA4JHHHIIIGIIIH65796666699A999IDP989A8C888A698AC666765688AODEEDEJKEKEHHKLGHEF8444365447EGGKIIIIIJIGLLCEFFFFFCEG888855DCAA997722232223537111-2-31212413331121221116AA86CCDCCAZB9 4342A8B-K8968CJIGLFJJLHRNRHEEBDABCBC9B9B9BCBCCFBHUKPgOKIJIGHHG7B89F9869CB8ADA8AB99988AFCEMZGGKKQWMPEDDFHHL3FZA*hgbolTOVLSRdR**V*K**u4*j*NXJQ*SRkVCRWRLbFJmSdPRmFJSJYYDLZMKrQhjBJFFE*A9AHGsUlsJYWMNSbMOL * d.81 FwdE/GAPDH domain-like
[  84] 552514ADFEFEEGDA4B877A8LA77B576B977576675575457645465248363447665166 CJK6TB7C88BC99LLMFF-FJ88IXFGFFGFORLSIOZZCLJUIHIC9FB9LMOFFHA7JFL8JEZSZQD66668553364G88667BBEA7H771115DBDBJDJEF33333332323444456657665775DCCCC456CAD7A98978878666668866BB9E8565664474755ED967764JDIHHJIKHIJDJIJHKIKHKKHKIKJFIHCKDB9AA9A9PL8BBCCCBBCCDDBCCD889BC3848B39232A9779868589698A4455444555588666665665555565545555565445555B6E4CK4444554A6AAABB866596776E8774PMCD7G6A97B9A6323J9AKHHD24444JDXRQHEGHIHJJDFGHDFHFFFM-GGRGGcGSTQC2VOONNLQPNMQRNPCADHHSIIJKMJTAAAAAAAAOCBAACEB33243444121124331342132232131ACGPE6FXPGVcbZZbbSKNMJZZecUUUUJVgVqNZSO7EOLJLILIHOPSPYU9BF8978DE66666669B8NJG4LFGAA876886775HDHBFBCA9GIDIHJBD966666546645665665556668597FCCIGBGDJHHFEFFECHEEEDEGFEDDGG333CB69442444MJJGAIFOMMNOPOOQO-MOMOOONPLOMNLLMNMMOOQOLMIGDMIMLMKMMMMMLMKLLMIKFJJKMC5FHHHHHHGHHHI4467AAAA9A9998ILJKAAAD8A35655A889MMMIMFKDDDP8QSSRJSQKNRLOSIGEJ6696877669FCFIEEEEEIHEHHCCGDFDDEEG667743A78888BB2222222233421112-113211-11132412111135855776779B7D 763368G-XGC2IFLdQXSVUVSghccIIEHGHFFHGHCEGEEGEELMGPXZkfMKPJMPONAGD9995ADCF9BJC6KDABBA9B9A7DUGQDNCMJLGGNEJIM2JtMgegZraeONNNLVRkgPqO**Y4scwKLLLXNQZNHOLKHcMLfMSQQYJTcLRLIGTQYdUYMBJNRI*FEGJHfXs*RaJNNWLKNR * a.100 6-phosphogluconate dehydrogenase C-terminal domain-like
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jfo-*RH9hjxZagZZhfffbffbZUaSbabbXcWcVadYYZafbfcebcXbcZbccbbbbYYXMZeWaXXZdTccXTWaSXZYaanWaYUaXUUTMdXnsr5**t**********************Q************z*************r****w*q****t**oMpiZ*WVaSa****c*pWXfmfdR * a.5 RuvA C-terminal domain-like
[  86] B9ABBBC7DFFEFFFBBB997A8CH77ECCEE9AB886667668B6D7A7CDEDBCDEEFF633G435 6GM4G83899893686766-6945886666669666DCEE3GEDEBB9587369D55421CC86FCGKHD55111A88446CF73567NQPL-LA95--8G7GEOAMBK333333343333334A9BBD78AKB79AAFG346LCGHEDA9C9977748595886DKJGD364122262212MGGAAAC97BFFFLGMLNNEMMMOOMA9GGEILKN7A9CF9BCDDDCCNRAAAAAAAAAAAAAA9FCFDBC6B5BD65755DC77EC655857A9A6676333855555665456343333333333333A8887588864DBGJ6668877E7FCEAA9DDCIBB99E895766FC796A977987B6AH7XA77833332BALOPE68CAHED4444444444C-NKLHWKMGBJ62EEEIEGKIFFFG8989499C9A9A79A44444444999548B911-21---11-------11-------111256A53BEC9BFFFFGEDCCCBEEEMFFFE9FFLDDBEE46CGDDEADBEBA8K6797B533A3334323333377ABFHCB7A95B76663A99A898BAIIOJgjBB742462223123533333335757B759A97H9C999DBCCBA88BCBA98BCEAFC1-5896C11-111899B686ABBBABCE99-C9B9CCB9B9CCABBBABEAAACC78ABABABBBBABBDBBAAAA8787698297776A978766223544334566675M788888884666564469888878686D7999A89CBABAAAADEC3222232225AABCAAAAADB9A978777779892222457CBB779A43334333A3411211-22122123333122311119C9AA8A8986EB7 IHIJhge1*fdSNTPSaYVWZcYcbacZXQURVaTZbaZYWXbUSPSZXfdafeRWTbUWZYVJNMHJCNIKLJNNLFNMJMPPNRNJLMiOacRdOKKLIOLfYe7k***o*dpgeTRVQQaRvkRzS**l-uY*PURQiLYaRNWQQTVOP*QXbbjadoZmfRTuagev*uPIYYV*ONPof*w**Z*wam****p * d.159 Metallo-dependent phosphatases
[  87] ----1--1111-1111-31-2-1-511343212----------2-215--331-232-2-22------ 64E3H8BAEEE95874877-7822AD7777777777ILCB2G9PFIFBB9769AC37H229FABP5CNOX78888898G6XF3222117853-435B--4C754D5D7A1111111111111137567B97C988788AB322I1IDGIAAB4488A899B99A8ENWYC5C777769576753722D84A39AADADBDE8CCDCCECEEEACDFI457ADBBEEEDEEHM86666665666666665446MK6DMME4JEPDD55QS96467AC9B8ACIECEJDEDHCEEAEHBDB67866677A7666FJIFGCFFH9I8DDEFFFGIGF5FAHCHH5DCES99HNCFB2-TTD2225422AADG66591566654545563FGED885D9D8999A99A97AD-EFIEFFHIAK74MFFEJMEKMKEGEC66587HAABAFBBCCCCCCCC9576B97E223222223346446746655555534531468246997EADDEGD99AA9AA9ACCCB8AD9BD8B523668C87859798C87BB4B48A625346348789A67573636638722213635677373353AC19744353333332144343334523488BA8A63A386A7888786798879A8E879--74984222222A6B8759688D6BDA66-86666676888C966666977CDGGJB9979899999999999A558555653EDFEFFDCDDFD113224322698742D6D6456882576524473445446437BF9BCBGEBC9EFCC4BCC5444454343877F88887CADDE57C6976889444432A3774444--------o-E221261432265244242722533365C667A7872725 B9EJfWP-xPBAgheWbaWckuf*uvlRRNPOPjoeSVOTTSTLKIhek*uw**hapdbUTWWOJBEG4KF9KHPEH3FJBEFEOKCFFe*KbdjXRPRbMJZkjS6N*l*p*m*s*aXYUZeW*xP*U***1*j*UWYXvWc*nRYVYRpWM*coXgrZ**b*cRa*ek****wDQNE*8AEPI*up*a**QV****k * f.37 ABC transporter transmembrane region
[  88] 11-1-22-1211112---111---2111--112-1---------412---3115-----11111--1- B463w2A4444DC9**tZZ-ZNAA*sYYYYYYUVVV****5fca444438345BC65A22ra55*i*hn*E----1111-113---114432-3--2223f353*3557444444433333332---12--212-45565---*2IOY1dea11111111211223hV*8111211131211435331-252*99E9ENAQBAHEQZ957SScr99m555G744444445*2266666666666666377442-4-22-1---4D111111212211111111611GA111311231111111111112111211111211112-6B4433U43241w2II----1133-3-3--656--51---11311-26-74222232228BD3*4237T33366666655663-5555776384227JHQ547635c44J32333E2232232222222223723232422223333223222222223222222222245A3223223CJKFIg*MWWMBBCJ****PsFDCM4H42333R22G22L356I82353111K3222222223F532212141-662311--3231434213433*g132------------111--11-111322DI24773345534333R53344333333841-54322222222U4f8458566N6POA44-748466B5AA7BB54555666BYE**86565676666566557A4544444228BBBBB6777B622235857977754Ht2c222222222222222CBCKC2A232iSgkam*u**KRUYT2yf*2222222221222K4AAAAF43CC55C555544422221112332243111-1---1-111111-1-12111111211331----1--------2O53 3311B7E-P9C1HFrof*i********WXYhff***xlchefhUTPrl******lY***UXSACBAD97CCBBC9EA89A9BDDABCFFINEfTaGBCBBILUMIN-KMG*YqnlfiLKJBLNKfoHjM**m4nUtFMMHRGLUNFMMHGOGGcPiINZTiq7dNEKaDFnZfeS7956*87888P*****wEFdWTWB * c.43 CoA-dependent acyltransferases
[  89] 55214353335344332243443272264451122231----13221976ABA2121--2-3221123 9Fd3C53499643358966-692286555558BABA8EFE1A8G442-3---4451-1--6865I459GH638553551-2A2122--5574-445---6B688D9B67--------------3254846236A8KKJQR---T3E67956C22111114327843HD9M1211111311116653344345644444335343433333666734455454--------I8211111111111111111112-1-11---------1----12-1-1323-1--1--2----2--3------2-13111-1211-------656352222222323324453443572161322864326-133---4-2392j44431111127AGE5539988B22222222225-99DAAAAD6E55A3367889999854677G86CBBBD5B2222222223417A86-------------122--1----------143132455362225225-222656633222276C8996--5546A231AC72D6-15677A4311-----222762FL955156372444263523316A56C5Xh251-1-------1-11-1-11142256769A46998386757777566DBA6687F668--15537------26222425445554A45-4344545453454445445267341133232424234344224243333231-399889989886---7-----4434E3K24----1-1-----3-511111-4-115687775B87747445A7822333223256DD75556569BDC44443443332121111988558844454454731-----------1------1------18--2111212694 DF44efd-N658B8EDAF8CCACDB98FF9BBDFGGAGFFAEDFAC8C9EHHMOAC9C9EEE8867343766767783686AA976778IHHAHBLB79A9EDAD92N************************9************y*******************cKSHLd***W3PHA*8C9C8eVUeEbNIFHFGEH * c.62 vWA-like
[  90] 442-1398DCGDEEAA12443426F778336D211---111112213212422111121212332--4 5899YB6ECCFC6Ap*oVV-V*EEnqVUVVVdzx*yp***6kDc799D9776LGGDHH33RTb8IKUSVTJ355533323A8A33345AA9E28772--AIDF9GECAD22222222222222346479644454BCCBA334B5533334822333333333526BA83433343344333FFFCC217K6ADDDDDCCEBECEDDC6B977ACEDAEE9D65666666D96999A8988999989A899B83656647242656666674576566666797867755555555555576676667667644455444464686C4445444444B38867656A763B554299878A47765483153D2BZQTg45445GCrYbHCBhWkdaDEDEDEEDEBE-GIRGHZGLFLs3KFEHFEKLGLIKPPIZNLLWFDGFGLT44444444G5445GIE111111111111111211111111112114SOWK5BgXMfOIIKMPLJIIIFEVUKKKKDKdLichok48MMLICFNMVOYXXRB9M3353I95454443334GHMCZKHB9A947A8793GJGIK9GFKNLHNVQAA887324454444444444443553833IJ9IRGOGNOHQSUUSOVbTRSTRRZURXT2-46A74232222ECCC8ECDFFFDCCBDD-FDEDBCBDBDFBEBBDABGDEDFCDCCCDBBCCCCCBCBCBBCJBBBBBBB51DCCCCCBACCCC222G8888889887PNEI5557A8577765887OOQQOINCDBGDgfghSZTVTRPTSQKLO8444454444FFFMCCCBBGGMFFJIDFFEECCC67772248JHIJMM--------415-----------1---------1---56444242322B6A 4121HJE-K773BAHRUXNiaUbmckfUVRRQSLOLLOMOGMORQPOWLPUPcRLNQFKLKKNJNDDC7NBALFKAB88BFKLMPP678KTJUTSQFHFDCHLWfX2JnG*LVLMVJEHEGFIGVSDXIy*Y2ZPaBGGDLEHQCCGEJBKGANDKGFIKRQHvJ69GBDDNUJh8GF9yDDBFGmTfuTWd9CIMOND * d.38 Thioesterase/thiol ester dehydrase-isomerase
[  91] 333221ADIHHIHLKD2955453-K555A4D4532--1----21742221764-21121117442-56 DDR8jB8FEEJ666LONJK-Kd99apJHJJJLXbceYi*z7TIfYIJB9IC8PLRFBE33IIOEkDljdUD72225755245K33544456413121112D2C5R6F6611111111111111564353644465ADDEC333HAG85A5561145112331365FGEI82112232122228B788982E5KEEFEFBFI7EFECDDLCGGHHCBC7646FHCCDDFCDAG6ABAAAABABBBAABAAABE94D3GK4C615JM66CHG5798E766757555677877777777868666666666666676445366688867FAA9D99D9989G66545442452533216464645425A777248D4JMFFH22222JHXOaE8FMKGKI789B8AA899G-KLMHMPHKEUN1QRRLaXUXabUYGO9KAECJDEGFH9J77777777EFE75ABG2231122222111111111111111212249OJA53A77DYTVXVVQPNPMWWRWTSST9OWPcIYSN15DEL7F7EDIEICKFBAB2757B65443444667E8776A333224451213DBB345444FGMLOT69612112222235544333343412545897CA997P9A596686B6866575675841-27754111111CJBF7DHLJJOLNNNKM-IMJJMJMJHKIMJLLJLLFMPJLLCA6EGGCFEHFEHFCECCEODCCFFFI21B888888888881116332338778678MG333A2412221135177A9D586C7M6LMPMBLJJDIIJIFKKK4223242223877A666568C989DCECECB8B9C666113A997778111111114231-11--31--111-11--43-----35432364547B96 3356oyF-QA6158Nuw*o*q*p****SSRPLNPLLROONLQPKOJxek*w***ozkfRTPQKHW9HGFHCHSBSJLGMMFOOOIMEDBo*XwThPURQIUEPMMU-BwX*JHBMIHDEDFEDBURBfF**M2ZQkIFDBLDESCADDDEBIEMESDGNGNA9QKHKHEQOAECMFMNG*FBAPRps**inyFJwoknL * b.35 GroES-like
[  92] 885368969888888567796A6A78853278334334233444655893344444475584847-34 8DB2PAAHDDG8765A666-6D22AQ666668GFGHAOQS5B8AGCA65787HJK97D2286JHGHOJHL554445554233A34232AAA93ADD---5E656H4J8M444444433433443555766559459A987111575766557556686777667569878463635563533GDA9A542C6FIIIIIHIJAJHJGIKFEFFDGHIF977EFB7KKKKLGOJ8BBBBBBBBBBBBBBGA98FCG67DL85BDAGH55GH8A6987C99778ECCC99A99A89A9999AFFFFGFGFGDDFG99B654999F8HCFYDDCCEDEICH6G87ADAA9J37185892HI7LJMACAB55AA4H443BCAA523335EDOCF97DGNDCBCECGBFFBEDP-BDICDNEDBQ65TJJNKLIXSMPRAG996GAJGJFKGA7AAAAAAAAJBBB568J2221111111113357343411331111224BL63CHHDMJKKRLJKMMMMJJRRNNNNFLPKaOSPM5AKKEEACEDHF8QEQ77D5955A989777774449BH5QW876AA5767772RIN7O6CA9AABABBES312423323315466666663132167B7ICE6E8DIDEBAAA8BHEDDABBDBBK93-46648331222LEMKIJCTPRYTXWXSS-OURSSSUSTRPZTSTTUTSbXYIJDGBUOTPSRTRSORPSPPSNMMENNNL82KJKKMLIIMLKL332533333566666CBKBABGFG7AB97AEGDFHHCF9D897R9IJIIFLKKCEGHGJLJL222222222599AICCCDCC9CDGEFGHFHGAAA555533CF55557743353443635----3-215-331122274123---597444C5544655 868GNGJ-iFC6CEDDKMMUTROSWRNHHIIHHJHFJKOKIMKHFILOJRPWVYQPHLGJMLJHJGEGAJGKHHHKJAIHEFGHHJDDDKiJKLQVHFHIIOCPPP2HaQoRSXXYeLPUNKNKlTFZKm*Y1VSoHKQQONMvTGLNJEJFEvQROLVLVhJbLOLoLW*VTaMDJDD*B8AFCSOWxOcXIMUZPJK * c.124 NagB/RpiA/CoA transferase-like
[  93] --11121--------12-1-12--2112-2-121121-11112111----11111113233-1-1--- 111---1--------------1--12------2111-112-222--------------11-----1-1---1-------111-1121------1--1---1-----2-1---------------111111-211111-11111121111111--11------11--1111---------------11121---111111---1-1----1-----1133-------------------------------------------------------1-----------------------------------------------1---111111112-12-------1-1-----1211--1-2-11--111--11----------21113---111-1-------------------------111--1--1---1-1---11111-----------1---1-------1-----1----------------------1----------1---------1111-1-1-1--11------1------1----11----1-1-----3-1121-32-112111211111111111-11211-112-1---111111---------11112--11-1------111111-121111-11111-----1-2-------11211-1111111111-11111-1111111111111-------11111111111111111211-1111--1--------------------11111-2--111111-1111-11-------1---1------------------1--------1-------------------11---------1-11----------------------------------------11---------111 EADIiij1pOV5QNfVSUWVXUVRSOSTSPQMQQPMQLHMJNPMRRRTTSTRSSMQURUWXUQNPJNN9MLMLOLKQFNNMSSPPPTPVLSOSXYlQJSMFSRlon3**K**********************e*********************************q****q***DoYW*KLIQW****U**QT****e * g.50 FYVE/PHD zinc finger
[  94] ----------------------------2-----------------1---542-------------11 129-2--111----23222-22--4333333243332343-231-21-----1-1-1---531-235131-----------11-----1121-3112--39365A45-61111111111111112-C2C1-1L2613323---D-L68766F----112111111368AW-4-1---2----1---------------11-1-1111111---1--1-----1-------12-------------------1-----1---7-----------------------1--11112222122------------------------11-1----------1----1111-1-------121--------------1-C2111-----156553112222311111111111-22531521214-111-313223341231111-242311-----------1-1521-1--------1------------------11222-153312232252111122423333-33135554-13335222224114-25C3-1-2-111111111422-45622-5-1-3----1-13111--23227u-31--------1----------1---11132113253231114431--1112-1-1131---1--3--------11-11133-1---1--2-11311-1-3121111112-5--13--1------------------------112133333433---2---------114-1--------------111121-3---3322321412421221212---------13343222222-23222323224471111--A-443366111-11-1G---------------------------1----------254 1---39U-917187578956645B56933453345765553376357354888B35A76677466325111231112-1111413433565984963568294484-2j6**********************J*********************************czkvx****1*G22111239694965347837G * d.169 C-type lectin-like
[  95] 33335353455544545233325647744544224221112115334B2EH9A121213233342232 A4B2B6554443337EA88-8733C98888897666669B3B8J57744333685444--BC83Q5DIDI433333333266214212B88533332--49456G79552221122112111143244B646B3B22134224A3JAD4968132232532334859E6J2232243422323113213143G585887D467G937B34454A6765658745955455E663344433444433454544I224333242243DE36554453495754223442223233333234223353334443333266572232D4363333645141C888533294455S5JN2GA836G4T34583223383763341121354D6BA367554333333332336-5954965668358AA5986746AB6A4546844335436222222224533294233131222211R211112121222243A72387423342D768D9DA6898778BBEBB3G4975458127645425335A9754494346422235433654B5844D548533834352557668T662362Qa85341331111221221122113334455534F86537565C9I84787866678D686--12364--1---46G64556777768776-6749768768678886786A65546574534463452675645547576673-66664664554511U532333BADA45G5522224314121223543473233458867B65H565C767B6AE2122222213635E45465M66574474647443564522B244333311121111225112-3-222241134312222111157621333232C34 HN48*KX-*dgQRNlVNSQlJMIKONQLMKJEJEMHMLMKJJKIGNkjILPHQMFRPsdLTURLJFBG2kGALFHJg4ILEGHTGDHFS*aVNRdZTGHaCXDKX*5GlW*z*wqw*lbiaghi**Z*Y***C*s*XgXXzdi*jYijgZ*aZ*e**o*e**i****tQe*eZ*cFW*T*IIHWM*yh*UgeQP****b * e.8 DNA/RNA polymerases
[  96] 654535GA98B89ADB87464779A334836B42643555554696AEA5898367566756883233 57A6H3223332-3DA9DD-DM22ALDDDDD5FLMLFFOQ645BA6437542998514-188EADARGKF8-3332221AjND6563933331411---36512557551211112111111124548574765346656343B6FAD788745555474627969CBD5-31----21-1-7F36544184EAABAA99C6BBA9ABB6DD7D9BB7BA975B6444468A25553555554455553376425---343-24734-11-11311-1---1----21--------------------11--1--11----19KB8C55556555576A66467579753D53A7*z597B2B7E4548312585C897122127BOFF96DBH9AB77777677678-CANDEMDIEC41BBACDACCCACDEF756659888955744444444G7648D6A11--------2321354141121121112247B74BIGEDKGGHIJFEIIJLLPIKMKMDLFDMKJKI27GIFCFBBACBAEIAEE999ABBB4333535555ECD6GK999DDFDF99G2BCADD7E78CBCBACAI7BF64767748373344445AB797AACA567774438BADCC5FKDGGEDEGCEOG2-16B6421-222JGGDDF9IJJHIFDHIH-GJJJGGHIHHIHIDIIHHIILHGHA7IIHJGFHKHHHHILIHIIB9BDCEF61CECEFFEFDFFE11-2655569998869B79799785425445566787644655E5DDCCBBDCBBFCBCCCC34342434438DDI78888ECB989869699667444412837733551111111132226----------2-----12-----33434443549554 6845JH81I6479CAzonq*q*f*z**IKKNHNNLKMOOONJKLLLoWhw****dhnUWVXYJLaBJGAEEETIXQHCFHAKIOKQ9BAZtboRjXaTaSRcVxe*26Ka*******WQVOclU**T*R**o4*g*RVWOhWqqdJdUYLzQP*R*pkgOfxNecYa*ab*TOfJ5JID*798WP****n**AIfXWZN * b.52 Double psi beta-barrel
[  97] ------21----1--1---1----31121121-1------------21--11--1------2-1---- 312-O--31112-2QnhLL-Lr33niLLKLLLpqvrQHUb2RFr2-1211--3181-2--SI9-aAcbITB----1----1-2----1---1-1--1---1-2-2-311-111111-------1-------11--13321---D-B753772--1111132131-446B6-12----1----42411----173333368444435642366383431---1-11-----2-111111111111111-111------------------2---1-111----111--------------------------------------1-1-1111111-1---------1-1----1--21-1---1-------1-1-17553-----22IEC11-839A51111111-112-45A5586849A-344578A24333213932922234345---------22----1------------------------------6GJ7--11111222521333344253333-44263256--32121-3141523-----1-12---------2131212----1---------11-1---1--1-7Q1------111111----1--1------------2---1--------1-----1-11--1--1-1----------21----33--------3---------3-----------22-3------------------------------------------1111111112233-----------------------1--1--34432221-2--11---3----1-----1-2-----2-1-1-113333---2232--1-11--------------------------1----------------8--1---11-- 1---kt9-D542A9C************cdZfZa**zcgcechfbba********rx**hcdcK8B6544854B4A4534449AAGC323*******44597FOfsr-Bo********mcbmr*z**l*o***-*t*Xgje*bb*xLbZfb*gS*i*p*****j************5SID*AAAQe*******8EYTRXB * a.104 Cytochrome P450
[  98] --------21--11------1--DZ89J4SPJ--22-133234IY-GY7KH6B-1-1111-------5 EYw5M3343335438AB66-6D3389666655CBCC8BCA8FEKF953366478B234--DDP2O5CMJJA122343364E69-3521LMeI-T433--6M5CDoOmbd-----------1-1-7529747D8I6jhfdbF56r4*ex*bbGIHEE233786PcDW***P252322252332RF955242E9IKLNKPNJKGNMQRRKFHEDEENMT8DFG8BB865666cS55555555555555553354324266222-35533453334323544443244421-----1-----333332223323323322132335I8CVDFDDFFFFEG8OJI6797D7F21E88H4MQI9B743751136123W6Xkbba45557JMehjKHJZYQSY999B998898C-jgzecglqGPT4KNOTUTLaeUIMORPFTG8HIJIHALBAAAAAAAAC98B9*XX11112111225A2133332223333111228MMC7AFDAFVRUUdSYFHIGSRegLKLNBMaViOQSN26IJGlTZFHccVVV9GISCF9CVG111212187HJb*UugJGGjV8*ZXXc2*k*pkviJZus*v**Ei35352111111433443544CB43A55PKBYQXN8QMEODJJGCKKIJGFJGGLGML--4DFIE------FFECGGAEGFFEFDEEE-FECGFEEEDDFEEDEEEEDHIF9DAB7EEEEDEEDEEDCEDEEIDDBDCDF6-GFEEEHHBCEEE--474444457669HmDR444313121122113ACAAC6B579KPabjaTlbfVcdfdccTW2111-21-1DEFFKMNNNNLNQOPWZYZbZXPSS98781-*2YXCFLM2112122221--------------------------38132534543*39 6443DCB-I942-1MEJIHBCEEC9BC785747A896877979778ADBADGAI8BA868785442112432345223222444534458E6J5C86788B567AF-D7B947F41H465A419A8486Ow31D1J4A9929526A17678B968353J2334527472295263-GH8i25244i4ASLEN94I4445 * a.30 ROP-like
[  99] 11-3-12411111115-21--114B4648989-223233333466356439653445354452112-- SLh3M668666868eOSJJ-JO77bQIHIII9PIGJ99995BAN64757753998347227AB4B65COG61------12523AA8EEYacU2b8E2--BbESKmSiKP222222233222228A48AAC88AIC4444464442HIDCECC5466666C9A8E6UAGNA2622222622225654444498899A9A7CBCBABCAA5588B8BB8858B5A8646666FD46666666666666684668-222112-22222--11--2-3------------------------------------------------2E28F333333343423774557424224468466C66688242225484U9WZGGQ44444SZrhxeNdmgicXCEEGCGGCECI-ovZbsjnkCMW2cNNTRRTRRPJOOiIOQGCJDDDDCACKKKKKKKKFSPLIGTI44344444442242664764448745245688JKAFGCCPYgigiVOHGGFWVbeNNNNGPbShVhfp3CfgaJbOKPoZRIOIOYZOVNQIL5544444MHSVabJSQDDEIDAISCC84IRCKMPRLKQROOcO6QK97668888898A8888888JC8CLKQOKCeaSlWaTEVacdaccqoccieYo*mqe2-4ROGO------IGFIDRGILMMIKKNII-HKKIIKLIGLJLJIIIIIJSUSIH9BDGDADGGFGGGCCHBEDPFBFEBGH5-LGGGGGGECGGH225P8A888CKIKfSXEI444456444344554IILMICN666PNVXXZXTZaVbbcRPNSU644444444PEPPSFGGGGNWaUUacUOXPOIMMDBBB78PHSTCGOP6666666684-----1-1-1231-222-1--22---654A988888KSE7 335533C-711-23133342342222222312223323332332331242323227322332242231222-22212-22233333-2144332242342414341-1W6*VRRUVFGECDHOGQN8RBn*Y2RMZCIGGKCIOF7GEEELE8VHJLNZ8Dc7eKH8FFElx*T8-547UAAC63A43J43365M5C5F * f.35 Multidrug efflux transporter AcrB transmembrane domain
[ 100] --2----1222222111121111-111213-3--1-----2211--12-23311-1--------1-23 25E3D6664354559A966-645595666668556658B9466763124ID777923A11A872J6LDKL711111111111712222899A19652--45422F63561111111111111122112212323153356444B6V5FF66E3333333433246A668Q4322223A2224B643322453433333443334436422445543412445221221125739A7679799889994644341111111111111111111324122111111121122122113233111111111111112211122213113522222121136333222243711612323346433244333211253J688C343348AFELC74ADA8G33333334333-CBFAAH9D4C517448ED9DEE37748568938C999594444444424444H881111111111112212222222222111125326322222644554856657746767765686567422665CCFA75766433594655631111111446597S43231374744451475574353ABDAcc371221111111111111111131132334338249465376886776776755668691-2535611-11144443554445444544-44444444464444444444444433244344444444444444444434541544446545444113622222322254C2222222222221222222232222233644743439435574437---------135477666655477AB638336567645--53445555111313335331111-----1-2-434---13-22211111111115876 31--673-B51-75A44775364834744558A8CD94454446654468AADC65556344723111121222211111---2143222464545-1-1111655-2*L**********************1************o******y*********wq*******AC*P5NOA*766dHGegW7LHHcbslpE * b.47 Trypsin-like serine proteases
[ 101] 33111-5865565764-4242221C56543842122223222344336246772-2113114461-13 9CE7SB6AEEJ769OTPCF-ES44MhCCCCCIXWcZQY**BQ9fAB8A4B76YNWFCF--HJZ6IHXRQSE53335651144I33333324524224112B5A9D6C99----------1111254444535444899AA223A59AC9A9958443335556676AA96333333333343C9A8A234FCBEEEEEAEFBEDDBBBHGEE9DEEFCLKIHB8777776G74777777777777779997842325724222584455131364544444433335533333333333344344444444452244422242557F666766776737885554B66316463399474232236423135D4BMHHC22222G9JEO769DFCEDHIJOHFJEJIK179F75O8ETXD-RNNPOPcYScXXGGEE7IObHEFGFNQGFGGGGGGDGE86B8B11121111----1111-1111-11-1111BCTgD4FUOGJjfiffjWPPPKgfjnVVSREU*b*RicP36JFIHDFDBKHRFQX5692334F84766666374FGB89A39557757447-5557658986666FI77434555433322311121115233365EC5BC6QAJFEEEFEECEFCCCFDBEFFEI11-7653111111GCBB9CAGEEEGEDEIH-EHFIEEEIDHEEHGGFGGFPSPDCGH8HFEFGEFFFHDFHFFDNCC7AABC5189A9BBA8BCBB111844233AAAB49HNd565455-22224547QQRNOBJAFCL4QPQQQVVaJXYTTENLM6332243334988E9AAAAEGBCEBCCDDDB88822222233663333--------233----1---1-12-111-13--122112312222429749 --35CEF-JB81FICLOURYUWOafZbGHFFGFJIJJHIGGHHGGHJHQabq**TRLGFIKKJDF8ED7FCBGCDFC7CBBDCBEH99BRhUOJNKIGHBENLHEI-CdErZsWZWXKJKDKNLWaIoJ**V-bWoHKKFXNJYICLIHHMIDgGNKJVPkdGgNPLhFLREVXG9ED7*989CFaPqqUT*GDdOeTP * c.82 ALDH-like
[ 102] 434246BILDDHGMF9468A9656B4485598426235666847646658BEA4AD59KIG6655-33 9DC4K69A679677dux**-*VMM*N******PRTWMLUO7FHH586549A398B58844DDC4LCSHDE833334344275E33433CB9C1D553--3G695MDF4B1111111112222275554775584867759554B9HFFGAAH7877565A6A8E8DIMP86846766856577878876476HDEDDDA9J9DEFBDCDACCAGCHI4BB8784677677CA3444444444444443343463413316433336644225223255565354432222222222222333333333333352333322216GEJFBABBBCDEADBB998DFEDCC5793461EHEC669A877775856A59A56B11111DEKIMH77KIEJM6877667677A-JIKGKIKGB9F57CBBCCAAJCDA9I899BC8B9AD6A977777777FBB8AFJG32222333332233442342334436433297CA6ACCAIGMNILJRGIIINMOONMMOCNPSLMWPP45POFEPEGEIEDCHDBBAB988C84444444588JIIC8F86CAC675AB84IDKEEFEDADBLBPe9G57534666656454445554355778786788BA857688A99674776868669792-2842B11-1119B894B4BDDABBABCB-DCBCB98CAFDAB99B99BJHF65867DDDCEDEDDEEGDFCD98789997427557676785552227444459899BEE7B767565445532565CCBEDAC889J6BADBCFA9DDIGDEACC466566566865657777778688C9DDDDD9884444118E9876773223312133211111---12-3122211212311286788A7AAB4F7D 65898H7-J6E5A8GBFL9MGFLJHGLCBAC77BIBAABBBCB9AAKHDOEDRMHELLCB8H86435B433544544338743854458DPEFMLIA7AC9DADDZ34NKuQWNMQOKFJHIUGxrCsD**X6hXvKKFEiHJrOFLFHHS*DcROHOWOSJKQNaEUGWLGOaF8DJC*GCEEJSMTlFZaDEFKHIA * a.25 Ferritin-like
[ 103] 33----A56667A968-3613--4SDEH58OC------111-137-4-11966---1----211--Da 8LC2977888847495844-48118244444473C6ARKM365715545111E4F141119AD446788A41111111----55-5-3------------B1H743B54--------------11----1-----ACC57---AD5BF6DD335444537858318CB7B32223225322365152---G356666666326396826755556576AEB625111211EC31114111111111126351-2413315223432233-23333241-------2--11111111111-------------1-----------12344431111----------1-1--6----11--2-------1----8-6955I111116HKHTKBNA887A9999989899G1DHFBLLEANEA1B99FKFTF9CKLBd488K27585965K5555555566645632111111111122212222222222211111A7AB-2A98EFCCCCF7EDDDGG8DJKJJAHDHG8CAJ11HNIO96F9CE93A4IC38845873434323NTI9664--3-341-31558-DB96FA631ECMBDX-3-114-333333---------31-5A44626C7A49594668779B3B875C64688C111G6-81111118A7A4779998988B88-9B9788878B989889888A7A4477877777777777877777876777851777777777778111B141115988BA815666635333333396744771433388CCCCGDE8GIJIIG97C311111111D21191111175767A777777888777744--775555--------3------1----------------------------1-9D-3 87-155S-fIG9MPSmSkUSMTKenWZKKGLKLQPTCGFFECFKHImcXeuss*RW*XOgdeCCBDDC6AC-A88BC3CBEEIFBB445RY*S*OsGIIH8eJMKK14*H***x***nomejzs**mxm***G*p*moyp*px**ixngk*iV*v*vxp***Nk*JQjYZ*EHbK1qeI*545UJ****n**3Cffv*S * b.6 Cupredoxin-like
[ 104] 443485B4CFEGBCEMI9KL958G757498544341B236582A53IJ42I8D6967BC4A3236231 9AE6DBA8889779E8889-8966AD8888897999A89E6CEHDG8A98889B966722CBC6DBB9E89B888A9B77CG89ABFA96DB3K4341-6545486HB633333333353333944989D26C256MJbh756B97BHJDFG8667944665CD6D6B65344454444443A7BDI994699IKIKLGMMDJLJJJMG9DD89HJME87A8CE877779DGBBE8B88888AAB8889E89B5665565545BB4566558654977BCAA788BA8AAAABBBABAB8888888889888B886668686EGA7DBBBCCCCHCI9BIH99A9AA8348FD7BHHEGEJ8DHDBDGG678AKDA878355459797A879AH9AF55555555557-BC89CAFAA972CCB9FDAFAA9B7867878A6655766AAAAAAAA8874A9AF333222222235548864A8445553333377B968A988EGGGGCD9999AAAACABAADCEBAAED87CCBDGBEBGFDCGACCGCA99BB9898888C9BIDE9EEA97JAAD99983IHMEGCTGHCCECCLCD64355443444344333334457EBCBECFDEABAA9GBCDCADECBACCFFCDCEF2-6EEDC112111BCB8EBCDCCDDDEDEE-CDDEDDDEEFCEDDDDDDFFGEBFFFFDBECCEDDCDDBDBCHBCCCCCCDB1CAAABAAAACBA2258AAAAAEJHGE9FADB9BBDA9BB7BDCCACAA9D98888CBDDCE9CECBEAABDAFB4555545557ECBFDDDEDFEFGECABCBDBBBB565665C46666873444344353422222---2-211----111--11149435688858674 8645LOD-bDO966CCAMIJ9FILJINFBCDHHDIDJFAFAEDECFICDJKJLOEFIGGGDF887667277686688698765676BBAFSIAGDI88897AAEDE3GhF*TW*UbTRSTOScP*yOmS**g5oaxTQUQkOQXUKVLUIbPM*VWIQRIFRTVVKHRGFVHPmKALOI*IHFJEQWToEnZDKSUUWM * d.218 Nucleotidyltransferase
[ 105] 111---2111111111--------4---2-31-----------11-121--1--14112221--1--- 1-M12--2------2------2---5------34351211-2126-1-----11-1----21--121122----------222-----------------32--21--------------------321------6CC88--3C2564-11933115-3---21-5HH7*------------723-1---22-555557461434543-211--54572-3-25111111E41--------------1-----1-------1--------------1----------------------------------------------1---24254552322---1222223--3-3---1-----1-1213-1--3-B2112-----1-576--121211------------42422134112-11-1111131223-2-413352453-2--------1---21----------------------------------21-1212--1111--111---22222211-142-31-222333---4-112-344-2-111-------2-3-2-4322--1------1------1---22-2IS--------------------------1--21111861721487876243121431F11E---1--1-------1112--2222222322-2222132232222222221---11----1-----1----1----2-11112-----------------A------1-1-2J3------------------2-1----1-12222-3421-----1------------1---55554621224443433435-------1-------------------------------------------11--11111---2 ----31D-2-1--1221221222111222223232222222221123233211112112111-------1--1-2------11111--11511-1-----1--21--7*3**********************T*********************************e********-35271--1532642425--3--2 * b.23 CUB-like
[ 106] 22-1-2112111-1--122----11--1--1--1----1-----2415--431-1-2----2-11-1- EQb6cBACCCBAABMJKNN-NQAARYNNNNNKSRQSQUXT8GAEHHGD8HC9GEC67H44HK99ODRedSA856557666A9A44444GFCC3B666--CLBGTOFR9P333333334333335665566557869AAGG-1-BERHINEFE8988698879CEA9GJMJ468555565565CAB67737CBLeekekmirUpfjknjPHOOKLknqHDCHK9ABAB99AjPA8AAA98778AA87A79BA6CCD9FG99FCCECBBGFA7D77D988CCCBAABBAA98898888998BCCCBCBBCDC9CM99FEB888A8IDEDBBBCFFDHCDFDGGAFFFGBBA8LDC88GFDEBB7F89DBE9378T84VLLQ46666CHTRPCC8HHGHGDDDGDBDACDI-GIKHIMGGEJF6KKKHGHFIIJJNDFEMSBECBAACADE66666666A9AA9A8D33111111--33789969A76688732324FEGLABDDAHMMNPQNJJKKIKKIHMMNMANUHEGKMI66HGH99DBCKBBEN9CC99B7AE8555555558AABEIACA74758897762ABBB97A9ABDBCMK8D6453644343534343363344536CCEF8CCCBBIBBEGGGEHDDFGGFGGBFGGC2-6595912-222JGCBFGFIJJKIJKJJI-HJKJJIIJGIHJLFIIIIHKJIACKIDGHGFGHGHHGFEHDFHLFFGGEFI74IEFFFGEEFEFF335H78767HKHE9CH99A89868698857768GEHGGBC8D9DCKJLJFJEIEFEFGEIGI66757776699CAICCCDCCEAFAMLC9B9A99797773277IIBBBB44444445842----2---1-11-----2-------45543233235BBC 5223FF8-F436436DHLEC9DAOIKG988887B97A97A99A578A5FOOMmSB9AE677862723424551-833-223562423233A6H48522251362B419cG*CFDIKDBA695ABJC8FBX*D1JBKB749978G68785AE7BC59CHJBHBBVDD9K6C7MTD84383D3431AK76JBBC61E738A * e.3 beta-lactamase/transpeptidase-like
[ 107] 44C5E49ADBBCCADF5623-1-9L99AE5D78A9AADCCCCBABADB89GFC776977776875-66 8Zz8K634557243JHHAA-AI22MeA9AAAHNIII9TVS7JCbJDA56863TFMC7A1199N6XEdMKS851119CCC7F7Q44444AA863D56---3C8IOa7UGM---------------22222421122CBBB9333AF8775776AB45223212346E7AA7131311132311A8D3377347FHHJHIGJJEGHLJHHQRBBADKGK8D7JKBD99A8A8YP677777777777777A4436L57557384646855AA845666444444644485466666666666666666665666684444444447NI7LHHIGGFIHFJAb886DD8HIBE2EA4D5WO8B896dEG9AB89D3X7FEOOR4444456qih437B88D6MMMOMNOPOOS-OJZHGTNQNQH2jRRVUSNhZRbeSJHQMITWGIHGMNQHFHHHHHHDJIGA5BC11222222226C-------------22225CK*IACHG8DMVXYWMFCCCCNNWQIHHHDEZHcNWWV-7EEGACA46H9JBVQ4F85768B6-------466A855ED685CD68766536844754346668KJ8B386333333336455555553324877JB4AA5YMCH5H8ED9HCQDBBAFCIHACM--18547------F5E9J8AHJKIHIIIII-HIDIKGHIKIHIJIIEIIAJKM77749D9BDDBDDDFCDDDDBF85666594-E9999999999A23-Q22222655578K6G222311122221113888687D195H9QPPQLPPLHIIHPAJII7333333335BHOV45445E6DJHFFADCDD9996555--4I774432232111112---------22-1--222-26-22111DJIJK6E666B656 ----CB3-953-556PBOKQFDBTONP7777679887676665656JCRTRbmiECE99GGE98625D4524C6685466665574355IWIBCKDAB8FC77FGA-BKBfQjKWVLDCHDGIHeTIZFl*M2VIgAHJGZFHIHEGHCBPHAWFSJHNDCQDJC8BDACaAEUC2AG2*233EAG7FGL6V51QEEEC * b.92 Composite domain of metallo-dependent hydrolases
[ 108] 88C878AA99999999CA999999C889BB988686668888A7678677CBC589788787886-56 99A6EBAACCC8B8A9FCC-EC55ABCCCCC9GDDDACBD9DEEDBA8AAE999AA9B66CECBD9GFCD9BBBBDCB999CB96988DACF5AA8322BC9ACBAACB1------1331111378959767787DDDGFAA9DFDBBAEED9BAA998B88A9ABHCFC88868888868ACBDFE99AABCDDCDECDECGDDDDDDBBBCCDCCAABDBCCDDDDDDCGCBBBBBBBBBBBBB8BBBBBDECDDDEEEGEFGDDDDBDDEEBEEEDDDDDCDFCCDDDDDDDDDDDCDDDDDDDDEDDDEDEDECCCDDBCEDGGGGGGGGFHECEBBBFFFCDA9AA9A98BBAC87AAA9AAAB9B9B7AA77E455559AC9998797A7889999898999288B99B88DCA5CAAAFEBBBBBB7676A8A9AEAAAA988888888B99886CA555555555511-132-523--33-445566C88787779ABBBBBB9AABDDBGBBBBADBBCDEFC77GFDC99D9ABBF977A8B888A8999AAA9889A87CAD9D99A8CA99969A9999989AAFAEEAA899988888886866666669999C9AA9B9A697A99AADB999A999B9BA9B994-8AA694425559FB9C99ABDAA9AC9B-BAA9AAA9A9B9999A99A9CB9ABEC9B99999999999999A9999999849CCCBCCCCDCC446A667769AACB8FACAAAAAA9CCBCA9AAAAABAAB998F7AABACAAAAFAEAFBCC87878978768BBA99999999A99888A888886666449B77667755565656865----5-556455555566856555697799898889C79 6622EFE-aDG5EEFGIHGJEGJLHIJFFFHEEGEDGEDFEDDHFFLHFFJIPIFIIKHJKKHHGGIHBGHLJJGNLGKLHEFGGFDFGBIDIECFCACBBGCNMZ-ETBXUeWNXLHDFCEHGLQHRE**N-QIfDCIGMCHRGDFHFGHDAZFSMHMCKODNEEDXBGDFQJBCFCC*CADCAQOuXHYKHAUNKMG * c.61 PRTase-like
[ 109] 11---1-1111111111-2--11-9334-53211211-4232347212--C55-----1--------- BDJ4*87899A675*ywYY-YvAA**XZXXVg*w*w****5zN*TOC99GA5HJHF4P--XbP9*T****J24552442465A52443A9B51733---3I558mBMAG---------1----123-341324517A99E111W3R6BD8981411111-212619B9K5-121--21-11-839443239AYRSRSSOTVBQSQOMQLEMLHPRNQ7AEID46555455nV4433333433333333337373439833433664367662632688111112155422221222222111111111211131244422214CAFF7769767776G9FG355492521A3261NJ955688653465423B3HlJJH--1--PIlNVD57WHKLE6666656656G-CCIADLCA7aQ-WMMKRRHXYZJOLO7F88GEB6ABBGG888888887CD458CA-----------------------------14IEA24MGEOdeiceiLNNPMSSWWPPQPCXnKgRXUW13KIGB9E99RDOHRH5I58CAAD433322225359886qKP83894AE8891495D99E8A8BB8Wj6B3111-22211313-11-1113235822EB6AKCO7J77DDEDC9DCFDECDD9BCDE--11652------BDBB7E9BA9ECFEFCC-ADCDDDDBEFAECCDBCCCIOLBB9AC99899B9999999899EBC8AACC7-976888757888--172222235364EP9G422113123322223LLNKNDC664A8TTRTGbSWJKKIGBWST1--------399AGABACBCCDAAEL9FAFE7563232--62EE89881112112-1141111---------111---------22332343331H23 EBBCkv3-M962FJ478IAABHEOIKNCGBDDFMGCCHJHJDCEEJFH8EBDLYCAJNCC694281241733315763834456A3311AI8879F31-424179B-4hUQBAjOFMEHLGG6HGEJJNn*81SEXGOPLBTEEBO9JNJ9ZNIXAA9*BCQDE7TNC32PKFC32FI7NH36D6OC8TC7A7EDGBAE * a.121 Tetracyclin repressor-like, C-terminal domain
[ 110] 442123344333433433886672E89AA9793531111111-3413413887211111125224-45 5685SC9ACCA868FEDBB-BH66IJBBBBBDGGFGMHLH7PNVGJDCADD9GFEDDC22OLDBTIKSRQG89AAAAA222792-222887A-A223--4B489H9H9B22222222222222779484444757BBBCD222I7C8A789734553332336969BAB8132211132222MDP88224989UTVRVTWYEVVXRVVDA7766WUW957HGJG9AA99AELA6666665666666586675957BDBB6679DE44DD563776DBC899ABA8C88AAA9A9A98897677677777768FCDABADDD938B9A888678777768446BDAD5543H9F115623423222435415854CEHHE3333389IML968FGEGEAABBACBBABE-FEDEICFIECD3LKKILJHJJLFE9C9D9DCAB9BBDCFAAAAAAAA8AA66BC9----------23323313331122111111A98639979AEJJIJGEBBBBIIFHEFEECEKIJCEBD98CCG8BDCBDDC9F98BC8766H85666666778E9A6775559447345547C77B88A98888FFA7732222222222223433332343444JIDBAC99DAGA9AA879AAAAA8BA9A882-6A98B2--222FIIGHHEGIIGGGGGGF-IGGHGHIGGHIGGGGGGGHHHIGIIGEHFGGHGGGGHGGGGGGKFEEGGGGA-EEEEFFEEEEEE12397645568688CICEAAAA8A577676669CDCBDCD777CDHHIHGKFJEGFFFCEII5553454555ACCEEDFEDIFGFIECDDDDDBCE777731A4555688---1--1-31711111-----1-------1------46353242324686 4333NNJ-NB8ACDGDGKEFHGGLIMGBB9CCDBBBACCDCCC99BGEIKIGJMCGIEEHGGA99687587786A7746779889B9BADPKGKIHBDDDCCELIO2L*XkTZUTaTNJMIKTMtfHfR**h2XUgINOLXKQTTJOLJETGFXRPOLTIIFLWMNFOFEFIHSKHQKE*KIFKNOQYwIfKNQRLJEJ * d.113 Nudix
[ 111] KK5GCLRCHGFGFGGM88KGLJIFJDDGAGJHFCOHJIKLKKKNRFPKHMLNNFBBABABCAA9926G 6A82E64BBBB5878AACC-CD33DBCCCCC7FGGGCACB8BAEA984B885BAA68811EEB6AEJKSLC32223545374C67B9A886729341--6C78CB48C955555554445555599877989789FGGHI4457AQFIHCDCA8CC877666E98ANNKE464434594455656CB4436BECCCCCCCDDCDCDCDBAFEBFCCD9DBBFCAA99AAAEA9666556666666656677794448843534543388844453544777544456644445444445444444444444484444344462GDBHBBBDCDDBB969IICBBB98775954ECHJGK7B8EAA65622558ABB99A555558AJDEEA9CCAB99989999889D-BEH99J8ADGA5JFFDGEJJFDIKBB898A6GA8AA779666666669CC65ICD33433333333334344333343344544266A85A9989JEFEFHEBAA9HHFLDDDD6DGIFBHBG57DDAB7ECDEBAHE89CHDBABID4454544898FDH8LNIEJQH9SLIFF5BD9B9AAB7MLRNHN8K642243322341311111126743677GG6CDADACFCGFGGGAKIEDDGHFGCGFK1-6DNDC221333FA887CABCBCBCBBBA-ABABDBDBDBACECBBCCBDDD899A9BCBBAABAAABABABACB9AAAAB63B999999A8999344855545887A8AIFD3333443333225557777778879A8GFGGCADCDEDDEAA9A776757757CEHFEFFFFGGKHGHBA9AABA898544476H67777BB3334334365411111-2112211222-1112222266766B7BAB3B84 1311bbP-TEA8FGTADFEDBCCEBBCBABBCBBB9DCBC9DGAABAABBCEEGACCAEBCBBAAAC73B95C9DDC8CC8AADFD789BJCDICGC9BA9ECQSU-KaMTWXNaQSHJFIELDgYFOG**T2RNeBFFCRFGHH9HJB7RBCPHSDHIGNPMKDH8f8FMUaFCEMQP*HFHIK*gt*CifIMRZYcG * d.37 CBS-domain pair
[ 112] --1--11------------1---26----313-1------1-175-3K-5K13--------------3 BKR2452A4451-117733-35222353454283343A63123-2--23237557233--715-638865-72218D3-495154558GIKM-D-----2K4C1LOL4F-------111----24429V728DF366588748C3U38I674131121-4116536GGOA111111121111544111126A8GGIGIKMLDKJILKN5EBB79IJM578C1E8645634LM321---------2--333216235345222222446511214242955463733245555557555543543467466543112211113ASIEbIHGJKGLCLA7EII8998EDJ46DAG74MHCK8D1566656C1-3GL7G3394444255XDFG65BLCDE33332333327-GAG9B9KH1G81EBAEE7Q989IBAC3337779N886C377777777EGC14B6A3332111211-11222118421111111-224N5246559LKKLFMOCABAaQVTEFEE8DEXcHJJR-3KHIDABH5LIGGL6DHW8696863443332344lANA*kKBDND5NdHFN3kWujdTeCWGEFGOJDKT4886333325222322122HK9AEBE6J7DaBL6L9AFqGHH7HBKEFGIJFFFNJ--23769-1----A65A586CDEHCGKHJC-DCCCBDDACBDHCBBCBBA98A87954DBACCEBDDBDFEECFAAD9GABZ6-5qggE*dtY8G8---72222258564AN4F1--322-111132357776755684D9CAADHHLM6GGKHLhUN11111121137B9HDDCDDMIDGGE889A9B9894434-1E5JJBBFD221222222-2--------1--------16-1----3G845353234I12 3255455-7485A7G98B5C54A787745654534537268476577CBBD9ED9A369578742536-65664424-2143366722D7I58A7685442FK58Q-77Ngjko*qttnbte*w**l*n***5***mmmq*en**YmnbZ*TU*T*eV*5BP9LDCECEHR7OGA12416213-3WDJSCOI23FCDP5 * a.26 4-helical cytokines
[ 113] --1-123112311111111121111--1--------2-------1--1-2333-121-111---2-11 1222611-222-2111211-12--1211111133332A46-43421---232312--3--431-2124342-111---113211-1--222--2-----1-2--221----------------2-----1-----23343---223123--111321--1--1--22311--------1-1-212-1------111111211212112----1-112---111122222314--------------------13542241434333322323--22------------11121-41111--------------------------1111-11111111211-221-1-1----1-1--121--2111-1----134223-1----12212-122213----------4-34343323--11132112----432-222-21-1-1-11222222222111211-----1-------------------------2341---------1---------12-----12123211-1--13121121------2----11-------11--2-32133111-31111--1-11-12212323512--1--11111-----1---1-----121213-1111211222223332241222521---1-33-------141--11111111221-11122--111111111111111211111-111111-11111121111---1--355545445343--1------1111-14-2----3----------2222222--1--22222222411-1221----------21112111111211122-3232---11-11--211-------------------------------------11---1---11---1-- 4588nk*-wQQCHIRDHGEDEGHEGDGGGFJIGGGHEGFGCGGEHIGGJFEEIFDDGFBEFFHHKIGIFHHLIIHHG9EGGIIIGJBAAOaLHJNOHIHGAFJVUT1a*o**********************F*********************************g*ko****oBPO9*9A8HLYPcbFYfBHekjhZ * c.45 (Phosphotyrosine protein) phosphatases II
[ 114] -------------------------------------------1---1-1211--------------- 8592c684334A26dUSII-IG77*QJHIIGGJFEGyo**1cWS2113151145732811cU23*LniS*8-------11341121125313111111-2I222*39141111111111111121111411113112222211*1FGI5NNR1111222211211CZM*41111111311121111111221p66858D5DA6A8EJ612CCJR66M331B311222222y3-4444444444444424432323333332324A333332333322244433633AA22222222222333333333333333333333331227B4444C44455j3FF22223-7212541154611411111111232619522222222ECIAZ4228L47533333333327-8B99D9977911AEERB85898QADI462A377768247555555553C9864251111111111111111111121111111112232476536JOPMQdqZgkXFENK****P*MJJD6C91377Q14C51J565J64262112E1213122234E34915745125832222-A8AA53C2C4334**432331112111111211112121112338B1-2C4225889899OB87887978A7971-12643-1-111Q3U7338366N3MMA44-645474C4986CB333445538N9w*73735433344354553H344543411BB8BDB6866D6112457466545556Z2I11114111111133176AB717443MFUVPUqcfc8JJJH3eS*5111111111233H2333393966667363322222221122221122111111111111111--1---1-----1-111-11122122222223G13 2111hg6-622-44RdVnR*r******EFEIHGz*nVTTUMSSDEEgR**vmolYXs*jKGI533232133232322122233333486FIBV9E7333244I666-3Q9KAEE77sgggch*Z*zh*j***5***gjfU*ir*gSkeMW*UY*O66Mn3253G85365CH8E592BI6kB76FHCCAIy8C547955H * a.28 Acyl carrier protein-like
[ 115] -------1--1----1----1-------------1---------------23--1--1-1-1-1---- 3334444444453444433-334443333334344464543554543434445543343355333332233222232233333335333333331121122222343333222222222222235433333533432233333237434333334433333353334444333333333333111113332338888888A6778887674433A6843334436666663633333333333333343343334376333334433662333335564443444333444444444443333333333333344333444335343444444434544883333423--3553345353433431133332334333322222533343333333322222222322-3333333322323333333333333334343344433334444444433353353333333333332222222222222234433333333333333343334344335544443433543444445433333443533444333334333333334633323543464335333443453446643543254433333333333333333333334333343333335333333335333333333333312333332-33333333433442333233-4333333334433333333334333333333333333333333333333333333333333333333332222233334343433333333333333333333333334333333433333333333333333333233353333353533334444444533333333333333--------112----2-343324246623334333333333434334332 LIHIwvc-*SN5adaPQOQRQQPOPOQPPNQOOPQQQROOKPQTQQLPRSPPPOLPQSRSRTNOLHHG7IGIMJMKLCLLIIJJJMSPSLXKQQNQSQRPKOR***7cXP********v*******u*****O***tyxw*s***k**ti**c******p**wzrgk*jntey*pIPTG*ILFJMcgp*PyVLJbmbgF * a.69 Left-handed superhelix
[ 116] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----11N-313-142222212132222111222222211111122222121-2-11112111122212221221211-11111121212-2222222222112222-232**********************A******************************************211-5-1-12442523--12335- * g.12 LDL receptor-like module
[ 117] 33334252444454353433343464465445524456665555547833454233343333333211 5484664766644575566-673368666666666668775577746643429A9934335575667787433334333395144522112221111--14353573433333333343333334433334552484475111464444352323355554443343383231223331323222222258-45555645436664754411354441314--1333323731322323243333333222221112212111221211111111443222111111111111111111111111111211112222222214667466666A64945144344432532532556387565546452642-55587783343578IBCB9A997AA9999999898B-FEDDGEEDCB75978899D89AFB67989A8A989AB9A55555555455449742222222222222222222222222222244546369898B9AABA9777799BD888879ACA98B856A9A8A7667678A98865756652232332445566565655476669882937654756345576834432365555575555655635543437746553653576665697767775867762-2484632133364456544998475554-A65865768788855545444445566454444454444544545745555435666666667662223222226666368765343333444333334454454563537A7757966555767B9322222222765563333386576666666666833331164447788-----1--2211111-------1------1---111-22111311125-1 B87AVSN2*Xd8IIWPOQOLKNJIMGLJJEIEHKIHNIGIIHHGGIOQLNNMPOIOTZLOOODADCBB69CBBDCFE8CDCABCBBEEF*dOOXgcKILGHMHTVT3X*J*yz****qgcaitl**c*f***G***bhjh*fq*lVpdbb*eR*m*zhvUimdmbdQjiecVlkMBzmy*fleahwlv*Q**z***u*g * b.85 beta-clip
[ 118] 222234666776769666555664D67F9ABE55413744455CE78B7DHKG879666883342-12 CEG5GECACCE98487788-8A66CA88898B9BCB7BGI7AEF9A8A4C86DEBBD8225689B7BAEA667775874287965686KLML2MA96117ED9AFHGCD46776764655555377BCF79CJA9PKKKJ454E5LJLLFGJCBEFB98A9DDFBNHIOF775666789586887659865D7FFFEGDFF9HEDGIF7CDD99FHJ8EE8AB8988A8AAM9667777677666765445677A37839564GF66587962559697A955556556776666555633222322232329877756677B94EKAAADA9AEAEABDDBBBA47B6547D47987C99956498A848BF3BAAA77fB7wBDEEE998ABAAF899988979AA1HGFHGMEKAI98JLLBHGDMLHDFACB9AB8CFBIHAC9777777779AA8AHAA33122234111144463442543343333788A64B8877DEECLEBBCDC77EFDDDD8EFCLAB7B59998EDAA6CDAFDA9BDA978AAAC98877658DCCACGCAAEG589FD98E8BCABFC9BBAAHFDA9986E9899865C7664677C977ABAGEC9CC99H9BCDEFEA9EDBBCCAFEAHF314B88B331333FF9DCH7GHHHHIHIHD-GGGIIEHKJLHIHHHFHHGBBDCADBCGFDEDCFEEDDEEEECFEGDECFG74A7799A769788557A56656CDCEFCE6DB799AB577659nrBGGGKGAE5B7CCDCFCGHDCFFEFF9EEFB567686557GGGFGFFFFFHHEG9888A8888ADB9B66ABDD89FD-------1323----1-----------1-11-----89BA89A97A7ADG TH57IDC-YD96C9IAGCAFAEAAFAABCCDEDBEDDA7A8BADCCEBDDCGHFHLAECIHF648457347665659356457948869BB6GBABC8C97GEB8B39ZAcBKICAA7567987PJ6IAV*I2EEG6B84EA7H75A668A53A5A99*HQJDJK98D5DNEFh9CCEE*DEFCRZUb*AbOKEKJGHG * b.81 Single-stranded left-handed beta-helix
[ 119] -----------------------1-------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------1-----------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------- 3355TQC-O9D18ADQOcG67688A5A88BFDC897EEACEBD8BAOHEGFKGM8CGGICDFH34343143242533233355543455DkHOOWJ3456537IOH-L************************X*********************************o*******L4jR7P3358Hu***P*RBJBEBDC * d.42 POZ domain
[ 120] 22------134211---42112121---1------1--------1-1---2-----2131--1--2-- 7DV-712-----1-35422-23446222222222222322266722352222432222--BE23766666611111213444244444AFEC2C886--9G4KCEAJ8Q888888877888888666666667J6766AB22276FEBACCB4488444444AA8CEEKC4444655444448CD5523-67789899889978888898777B88A9787877555555967555555555555555557655455555445555655434644655555579744555555555555555555555555564556555546ECE9BBBBBBD9B7A7FFCA9A7B645A572233232246226677223O6B9DD92222266C6A6766666644462266247-97B6766686626224256775226764C776666676666666666266626A66676666666-122223243222226678-E96AA44444111--11------1----2----2888A44544266447444444484454544411111445544ABA87A8C8B9CC88B9C8988DAPQEUVM8G689695565545555555555565532DD5G88IC8G5LLMMKDDEKKKHHFGJIGI--28444------997A789BBBBBBBBBB-BBBBBB8BBCBBBBBBBBB999CD77A66666666667666677BB8988B5-DA999AA9A999--3C44444454545C7F777531544555555777777C999BGAA9A99886EEFD788844665444489CCHEFEEFEDGDD455555555544544-B36666669889A9995341-1-1---------------1----22362333245E8D IHk*NVJ-*LNCLJLLIMLINLILQJKKKJIIJLLMMJKJIKJKNPKNLMLLNwJJLQJLKLPOQPOPNNNORLPNPGLPONPMOZIKJLdFIGFIEFEFNLHVbT7V*kppmYdgaNMLKPRGimLvK**W5ZalENQORNPaIINROGRNIvOeTRSNfiVVNVWeTdyOzdKRMZN*RPPRTvbkjKqkadQXUSS * d.185 LuxS/MPP-like metallohydrolase
[ 121] 33334334333333333343443463343332544323345543333455454645334444354343 ---1-112111--12--11-11---111111-111111-11---121-3---21111211-11212222121111---11-12-111-22-111--112---1-111111------1-12222112121111321--1--1111---1--1112--111121-1-1----11-1111111-1211--11-1-----------------1----------1-1---------1----------------------1----------------1----------------------------------------1---------1----111-11----21-------1-121--1-111-1--112--1111--1-211--1-211-1------1-2-----------------1-1------11----------11---------------------22----1111-----11--11--211112111------11--------------------------------1-------2------------1--1--1------------141---1---11111--11--2-1111111-111111111111111221122222-11--1-111-111111111111111111111111---111-111111111221-1111111111-1111111111111111111111--1111111--1---11111111111112-1111111111111-1-1-----1111-11--111-1-111111111----------1-1111---------1-1--11111111-1111-----111121-131211111-------------11111111--11-121---1--11----1----22211-111-121-1-- IHEE99e1W886NQPRQOPQRRPQNPPUUUYOVVUXSTNSOSSORSRQNQQRQQPUTSTPSPPKKMML8KMOJHKKMEJMNLLJLLQPJNXLQNOONMNNSMMZVa9QvE**********************9****************y**x******n***pk*j*zy***yk8OWp*dfdPQVo**S*YBSJPPQP * d.51 Eukaryotic type KH-domain (KH-domain type I)
[ 122] 1121323466755665483332113226363121211111111251111214122342332544111- 8DI1O22211143243445-481188444444877745866324AFA44B91DBB65C22879C95DEK8675558DC321-611223IIcM1B55-1-8H396F4D1N--1111-122----2332444333-3866AB---83537754644224223553339BFB8241121152111753226956432222224422522445A55432223351154DEEFEA7R23334334333333333223HB839834869CC558A378875A994563546643577765656763333333333323578643745394-CB3333232323E7434ACAK362--4B224241--E-1-778B111414766654333A64877632323467766676777-998BB6665F5-ABBB977EDA982633234886586754444444466543347112-111111113222231331221221-124353311258BBAD7A333377A965554678F656533BA99875647A4A6544722461255454513586H21231153-23221111621231343334C332223-22322----------3-11155444649538246787A45488876A56736--14-1211----BD87794EBBDEBBBDC-BDDDC9CEACBBAECEFD7CAA65125CD98BBABBB89B98BB976BBBB31944465545678----11111-22142476544537-5482233344444222328D656648897889A6CDB4232243221266868778678AE549DAC9A993222-142221144111112122141---1---212--111122133---54663757A73H95 8633FHJ1PD9ACA8OJbQTSUNTUUZGGFJGHADAGGEFGHEEGFOJJOXYfdVVSLILHIACJ7A71F79HBFAD6EA8GIIDK659KUFJMIBBAB98LBFFH2GYa*gx**n*OJ**NpR****V**m6*s*RYa**JShQIT*d*qQJ*TmOs*Me*LPcoigUVpHTSECPRG*BCAHPms**P**99YYYgA * b.30 Supersandwich
[ 123] 44----5353353553-222--12B44C75881-1--------16332-2545-11111112-2--36 9UY3i637CCD222XVKCC-Cd22TfCBCCCIhejfoj**2UDZJg9K4FH4VUTAAL--RbU3LIgjvc72---6313-32M--1--546515333--2I3BAY8P9K111111111111111212633233339BBFC---OLY9ADCBA8877237755983KDHSF212322221232FFD57111C4IYWbWbbZgGXcXZaWKMGEGKXWg778OMJOJMMLJIbbAGGFHEFEFFFFGFFI9AHOM-3-77-3---1144882323238DG9998333655465565575555455555665535A9A445899D2D4AA333776527569221222H1222C151-A9431-22212232132M-8RKKP----2CFtWWC79K6FFBGJFJGFHEFHQ-DHHHEUFNYlO-xVVPdgkwvhbhQPLIH7TSFBGGCHP444444444CC645E5----------------------------12DY*M3AIGCNWZcaWXPIJKGVVdWNNNN8JoPlVeZR12LOILKEIGRNS7eF9D95737O3-21222253C6MDB6431223184322-778475944BCHDNT453-1--1---1--1--------1--267IG3E68M7RF8EHEGEFECFEECCHBECHJ--17528------48C95844444444444-4446454434444444444KJGA97847476657676667667I44344433-433333333333--1G121127D9A55LAI3333242231222247778759154H6OPKOHGGHFFDJCFAA9211-1111127A9HJFGFFLJGGJPPEJHJJCCD22221161BA66AA--------3-8-----------------1-------11211-1---3K29 22--B99-94-137EABJAHFHCGDCE988A79AA7BFCDGED998556KAINO88ABD657336131123153432233144464223122B7152121134435-4Z8NDCHAAC85B8A97AA4B7K*A-A9H69B6A7CDB687488B5A77A8HAD77CAC6655769C9AD86V786ECTEGY6MHFCB753F * d.32 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
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aZFDKFLEDDC9FDGII4IdKdUSWcQgLJLLNcL**LuR**l6ie*NQPNjNOZQGOPJHeLImORUNMHFEDTGOGRFFUAJUDBLME*DIBRN****G*gHGEKSiE * d.68 IF3-like
[ 125] ----1-------------------2--2-3------------11---1-------------------- 4242*23222222222233-32223333333322222432292534326211354228116622a25ILL2111122211312111114232111111127122Q251322222221121211121114-111112224311273234221511112111121212353311121111121138211111322333332222324243324424242212522222222228222222222222222233222232222223222222222222222222223222112222222222222222222222222222222222222A2565333556372332222338223222154122222322232122323522231111232323222323244244432323132435222422-3553432333252522232221222231111111124221211111111111111111111121111111111323222331342533376666335366665424322221132223443333242223211242111111111232222131111131112121211122133245E1211151333313131111111111212243123C1311122434112333331133131-1222111111111111111111111321-11111221221221111121112352124222222222322221112111111112112222111111111111111231F12222111411-15111811111311117323322222233336341111111111111122221323342222222222111111211111111111111121222232-322222222222122222222323222222512 968APEu-H642HGHA7DCBD9DEDGA57B7575857978C7BAA8CCFLFLIEDCCD9ABB67B88849CAC8B8G4CAD885A88B9LdL7qUkGEIWACAsp*APdY**********************6************z******q******u**z*o*Q*Zlxan*V6CP8q34543Haf*8beDAPcYsJ * b.42 beta-Trefoil
[ 126] 442553547556565224141313F77BFE94533144232222334254CA7263223423231114 4By28112333---46466-5511C755555786661C9A12453MB1-111519213--3353446689322223223222F21---UTfL5U662--9L69HR4f6R--------1-3222-1-5342123744887A222756FF64745622212223342E457423222225222277456449468DCDCDEEDCDDDDCECACCAADDC788A6B6777878AM666656666666666676666373874232555777652223333356533333332223233323233333333333334563334554666A9444544474AC7889AB97BA2396889NJ8A65655575462-394*6444-----76A782-17473323332333334-265425343E8-7669577GAAFC243817755556B7C33333333433223232222222222--11231111-11112222-286534D9457ABCAA69AAA77D9BBBB68F69789711AB4123239251361576677A5343353411-4565C5246B75AB66448767545A68886EJ6563446545434A977575674311688CDB535P9OBA9BABAABDACC9A9GICDM--2611422-222EA68BE8HJKJHJJKFF-IFGGJIJGKFJHIHHHHHHBAC6888AELEDDFFEFEEGGGCEFFCGEEFD4-ABBABBBBBBBB--23444448777327793328444551542264464434333ABEDFEBEFC6ECCC3B985222222222DHHE888979HEKK874555635433333269CD7777--------3-5222-2-3324322444423253332354537888638I7 2123ADf-9676HECEDFDJIJIUMTODBCCDCFEEGDDCBDDECDDADLPQaVIIGGBCAAA786851786A57773567787896668C8D79B767779AFGH3C*D*q*gwpiTTLNQaVrjQsV**q8ki*RVVRmPTkhNVPQFiQM*Rgacabo*Q*qQVpZZ*Ra*G4OC6V54365RIHPDIHB5bWTZ* * c.76 Alkaline phosphatase-like
[ 127] 22535545455343656244435556844466333453544336376616576744555454344134 5C84B34455531265422-2522662322245A8A4573698674255231344442338834537784552333338767D5465687883756F-159577E47B6-------11222226442436224B4755A9543B985894464677244543674788A635443346343368666A84779BBBBBCBDCBCBDECEECC9BCCC688C8CEBDDDDCBE97777777777777777878D8A7997A888AB889998A9A597888887888887777887677787777888888789A96768888BIBAIFFFEECE8G885EE6AA9FAD457FCGDPNC8DH9AEA68AE975D89643633333549DC3547568833333333335-A8798A9958616557685797674566533576444894444444434553D582111111111MS74A956E63345522223455543434AACCDCA8777688DI888866DAC5B6934655CEDC8D54E86C9K8797E812111116758FT9TNBGGQN9ZVMMM9HFGOFFIGR9A798CFD844344444522322222229455554DBADGBD9J95BEBCDDBBGCC9AECAAHD1-34B8J11-1118ABC77A8888897A77-97878797889A867866AA89BB7A87767888787787778A67767768196667776787711413332368A776P4G64547444333343555565579667CDFEEEIFFEBECBBBDD355436545DAAAIGDFGCAABED5777887755433311H8BA78882331211195634444-1131234111143412222CEBABB9ABB3I46 76239CB-XED9HHD8CDDHEFHQGNFFF9FCEECCBCBCABBDCBFBFRKBHFC6EC6FFD8455855576355474354555551248A8CA8FA8945B9IDC3BMHofsiadcRNVOSWP**M*P***3*e*LSTQjQQkVKSQMKYOItSXXRaKOMQOPHJgIFWATTK4fND*8B99CDGHNBJELQQMJLH * a.211 HD-domain/PDEase-like
[ 128] ---------------111-----22111112236356333333111251121132424323---2211 --1-1---------16421-1---31211111-1111131-311-1----------12------6-2322---------1--13-1------------------11----------111-------1-1-1-1--11111----1---1--3-------------2212--1-----1----1--11--1---------1----------11-----111-----------1-11111111111121-111----------------------2-----------------------------------------------------------------------1-2------111-1-------------------------1---------11-------------------------------1--1---1---2---------11111111-11--1-1-----111---------------------1------1-1------1---------1111-1-----------1--------1------------------------11-11----1-----2-11-12-111-12-------------1-----------11--------1-----------------------1----1------------------1-------------------------------21----------------------------------------------------------------------------------1--------------------------------22222-----------------------11--11-----------------------------------------------11- DACCYWK4*ToFONWTKOJSRQOSOPOSWLOKMNRRIRLPJNNaOOOONQRQQRGNQPSNLMRPSNMMGPPPQLTPPJNPOQSSORRTPUgTKWavLKMLWcLVeZFV*T****************x*****1******u*z***z********t****ZPk****H*v*ru**TL**T*OLOim**s*o*fLXWRSNt * a.22 Histone-fold
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bwaYdcMKOLOUOqaKnQ**Z2lZuCPNNeMSQPISOJGUJJXPWUQUIMTGJHVCUPYgIGHGLTRZ*YXQNJYfq*8hcYgONIK* * d.26 FKBP-like
[ 130] 11-31--1-------251122111--112142A412--4435-8B-8F75A742-22ZA-32361--1 n**-F146666--133322-25112722222265586AGD-223751--42-868317--8A7-P38KFD23------35636--1--****2*EF2--W*QdV*Y*V*---------1----1122415244V5KHHEJ---O22-6152-75---2--1-21-D5779------11---1D844343111255B5AYKE4EKGbYG4B6674CMG11--339EA8GEIM4266A6A724766677-5211D12-43-----33--174-1-1463-6467868211733336337333333435669434B64---566131-612222232625-133-5515366CB23--6431-242-112-3-3-s-Z56711111122A981--2322455445444535-31711A2476--64456578765767143A642522455111111113111122211111111--1111221111111111111-35B4-34336877AA99666599B6BBBA49989AKFC-1566321449581B614311134-1111111--424-3F-51-12411--1--K336491276CBux-6---1-1111------------------31-5-BB57565334532643316359144--24-21------13-31234BB6465844-B44747C587E7643565777724451322324244332523444423233--122222122222---3-----334321952111-2--1111-1126655648-214O979A6CA9798877544---------1--17131316456587BCABCBA92121--2-662232--------412------1--------------1---364114443518-E 1122uk9-3-2222-C9FALEHAIJIG4645564644454444555BB69CELGDCCDA98A135-12122-134-1--113332411178899E54341564343-7J9*w*l**imlVYbwj**e*a***6***YZdi*gp**QizXZ*eS*l*ll*BIUDLSIEzKFvBIKFCSUH*9D8O9KHDaDNM5GFCOM7 * b.3 Prealbumin-like
[ 131] 558435ADDDDCEDCE4384466764445535533332554454346746989376755544553153 GEP7A43344543465577-9722AC888889899977BF6A6A675675547686433396H499HADA5234433354659A68B8IJEA3G542116L8EGNBK5C111111121211115867899547A7C9ACA3336EBB8A773665535546457598BE835332224232358A55773659AABABAAA9ABCAAC89897AACA9877457666665I94555455555555546444452326624333657855472432444222333343345544554454333333333333354444244435HC7B9998999B9B6B65665685653655B4DDECA6577A4537675C6CI89B33323DGfVZD6GOLJPG78AC6C88A9C1NPVKMRQSFQD2LHHKGGPKKDMSLJ7A6HF9EEEFEBIDDDDDDDDJJI97FDC22222222221183326866655552212379D66BB97BQQRSSREECDCTTQTEDEDCAODVMPUI37III89B88JDD8KA7D96AE8B9656696566A9CA5AD7A8A87DF99838A7BACABD9868GC8H8659566656735434444489878A9GB9EB9DDJ9BIIIIGBHJIIFGHDHKIKE2148878211222AC988D8DHHFDEDDDC-FDDDEBDDEDFEFDDCDD9GEHADCBD989788999A989879IA97BABC73CBDDDCCCBCCC11669999A9DABC9CBD655587555552445DDCBD7A799DBJKKIFJMIBIFHHBFDH456555555ACCEKABBBBCFEHFCBGCFCB99965454494AA56332222222284421213-344432244433443244456698545658B47 45116591K676A8A78CA8888A98A88775667998678667677A75789B799587774445441534565543556444555558B688745564696ACA17D7VAGEEPL997BCFBSXBKEi*L-JCNB7EBE9AG84AAAAK68O8D8CF7DgAJDAIGEIVPCED88B6*7467AFBMOAOL66A576C * d.41 alpha/beta-Hammerhead
[ 132] 11----------------------11112221-------1----1--------1--1-----1----- -1---112111--1111----1--11-----111111111-1-1111-111-21211---121-1122111-----------3-----------------1-1----11------------------------------1-----G87966211445565464419A9F6455444444544-----------111---11------1------1----1-------1----------------------1------1---1-----------1----22221--1111111111111111221111122112221112221--------------1------------1--11------------------1--SKLL11111DBUXa89BGDEID7788778888C-HHHGFMKMBNS1JDDEJIKRQKKKFHFHDAEIA5BAEFJ545555556B9467B711-11111--11111111111111111111CJNG5ABB8TIMOONKDDDEDGGSLFFFGAFQGPFKMF27EEGBEHBCJHPBQ94A93333E422222224559944-1-------1---------1---4434BR-1---1---------------------66975A9AH7E88BAAAA8BA9997B89B6AG--24443------BBAC4A7ABB9AAAAAA-BAAAA99A8AB9AAAAAABCEDDD454B8ABACBBBBBBBBBADAA999991-845455555555--1722222555546E7A444626222222114CCDCD7C89AA1JKKJFIHKAFDFFACBB2222222223699B7777798A78DDFDEDD8893222222-441244--------1----------------------------1-------1-1-- 5657RWL-N8A3BCBRVUPOSWPWWTSGHCIEHMONHICHJGIB89PJUmVdlYHGHHFGFGDAB5784D6A7B9CD58B9FFFDAAEESqOVTUMB9B9DEFLSR-E*V*liYfpfYTNTfeW**Q*U**v1xg*QTRPtRSpZQTQOOgRIsVVSeWn*eNmkfQ*npYx*c*CKIM*DHEJPn***K**LLmdUkb * a.45 GST C-terminal domain-like
[ 133] 21-111--1-----11--2-1-----1--2241---1-------1-32-2781---12-1------3- 5Fh1A------11-1------1--2------13----413172A12---1213111-1--141-93846541111111--122-----669B-E33---47346A24B5-111111111----2----1---1718999D---F6VGG7ABA22----11--472DKJKB-1----------43412-----111111112-2212121-11-112112--2--------53----------------------1-11---------11-------------------------------------------------------1---------2-1-1-----------4--1121213-----222--1-G-D3449--111156231--12-121111111-111-74346363443-2221-14-121112345114-11-2232222222233342151--2-----------11-----1--------43941-----1111125111111-21111-1113231---22-38---131-32--5-211---------12--6342-3121--11----121-1-2-18747KI-1---------1-1---------12121121-4-15377-766447477665758656C----1-1------1311----112-1-1---1---------1-----1-11112321--1--------------22--111---2---211-1-22---61111-11111-3-2-1--1------------------11-2333332--332324----------------111111111--7599A988892222--11--------------31--------------------------112-111-111A-3 B98CSal2sMXJjagJOTOPWWQVVYWQRQQRRVSSSIKJJGKQSNRPWdYSVVLPQQLROOOGFONNALSGLJLHJBLMDJKLLLWWXQZWOTbgTFNKHIGXWVBgSj*******pkqkk*t**a*f***H***fsji*j**ri*lfY*ig*j****b**c*uiT*iu*fhxzKliY*NONNU*QbuTojFHYpVaV * b.70 8-bladed beta-propeller
[ 134] 433121B98ABAAABB-1545224533353531---1------1212223252----1--13113123 76E9M547997563A88DC-DC44ILEDEEEAGDDDEITQ6FCCBD959664CAC74611D9M6EFTHOJ933333334344E54444554417331--57364E5B2444444445554444366443657566BAA9A1116D6A668965755566565556997B64854444644548796532345A99999CBA9ABABCB97876BAAE9A978644444449B3222222222222222222234255644434333344322332332333222222222222222222222222222222222222222221E73A78798A9857274545558326444442BA386525752221333746C788444447ANMPBACFJGHEAA9AAAA999E-GGKEDRGOGMC4JCCGEFRHFFLOFC894GFDCDDECCG88888888D8895BAE3332222233343323333334333333344FG55DDCBCHFFJFJBCCCCDDQPDDDDBDIGYLPOJ59FFEDCGAAJEHAHH8AD96559A6666677887HBB4BB595888B5878279A575568BBABCD49422334444434444444444222499C969A685A657999966C988979779781-5CB9933-333A9669AAFDCDFEEEFE-CFFFEEEFFFCEFFFEFFABBA778979A9988988899A999BA9BAAAB419AAABAAA9ABB3354344458AA997BBD66675646664567577777788C8D9FFHFDHEDCDCEFCFDE8675685464555C777777876688A888855655556596554455333333337631111--1------111---------26554243336654 ----CC6-A55-457PKyjqabNxotkNNIGHFNNMFIIIHHHFEFeUShht**bZbhKONO345455454465554255455584232FZNKRJJ44446BA565-AhFRBBBACF78858C8GU6D9IrC2B7F5954D97E758886N54G8F9CJCLU8GFDBICJC9FHC58C9*776C9SQS*ltt79GEFNB * d.145 FAD-binding/transporter-associated domain-like
[ 135] 65-1--ABBBDBBCAA-253643H96661-7C---1----1--------------------6771-11 4567f4-6442947p**cc-c*44**cccccs********4xG*55552682BBCB9C--TVi1QLcZOcK--------384D-----11211133---1545774565--------------1-----1--1--787BB---DA53-3224--121---1-2-113461------------ABB8A--1G75777775967877877566666786AFDCC21------6413333332333333221113-11-1-1--1-22--------1-----------111------------------------1--111---211316444444444425332221-6-316-23-C915B9-1A---11-3171-VLLa-11-194kTe787YHXXMAA9A9AA797A-CCGCCLBKECg1QEEMBA9ECEACGQAWDADF9788D9J63666666C11129C611---------------------------1PXnR19XMEXJPSaeMKIOOIHHWJSSSSEQmJtk**t46KLFF8LIIaKNNZi25C-1-3662222222212I894sKP---1-1-----765-C-5--89A8HJ79---11-------1--------2-----54-CG7A8HE1676667AH7776B6H8699--1221-------42842214334444334-344533342333444444546411683665356656464644632324223--322232212333---7222227777-ME45-1------1-12--2QRRPRHR8CAL3baadKYLSNQPOLIGEG1111111112111522222562457798688566------12EEBADD----------1-------------------------1--11-1----1-4 ----FFB-F64-CCGHGKDIDEGHEGMGG9DCCAAAFFFFEFEFFFDE8BCEJSCC9A98A8B44231132141312122244454--1AMBGDB98778DEFLJO-FJDeKZFEJTDCDCEJDTICRDt*J-OKbCGECRCEOH7EECCIC7OEIGEWIQSDUHIKHCJHNaKR3787w655A8ECEPFDB76VLMHE * e.6 Acyl-CoA dehydrogenase NM domain-like
[ 136] 1-----1--------1----1--11------1-------------------11----1-1---1---- 153----1111----------1--1------11-------1-----------1------------1---------------1-----111211211------121-11----------------------------------1------22--------------12221----------1-----------1111111121111111-111-111-2-----1-111--11---------------1--------11-1--2-----1--------------------11-1----------------------------11-------11---2------11-1-2---------1-1-1-1---1--1---1-----111--------------1111111111------------------11--------1-------------------------------------------------------------------------------------------1-----------------------------11---1-------------11--------------------11-----------------------1-2-------11---1-11222---1--1----111----------------------------------------------------------------------------------1-----------------------1-----1-221---------------------------2----1------------------111-------------1---1-----------------------------------------------------1-1--1--2----- 333333F-F57597A68BAB78CA89BCAAA7A799BB8B8BABDCB988AB98669M87796875774652658575468657775586B58768A6784B5F7E1954**********************l********z*****************OXzU***g*xs*Stvg1795E34365EGEJANM57DHMJ5 * a.48 N-cbl like
[ 137] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------I--------------------------B-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-114552---------------------------------------------1-1---------------------------1-1--------------------------------------------------------------------- 1-22hhJ-948-LG*simUcYbbXdbbTSUUUVWZUUZSYRYYQTRTUWfdQ*SNWbWVVVWwFFAEB2CB7D8DAB6BB8FIHEMABB**si***HELISEJ**b1Y********qiYbch*l**V*****6***VdXY*Zp*rVtdkVvdO*c*pu*UaRYxw*EmUgnJ**g5fUWl9B5oB****f**GIGNKMC * a.158 F-box domain
[ 138] 221---5366666665155331117EA788C8--411111111-5-53E1855--12----422--68 58C989BFGGG7A6A99EE-EF669HEEEEE6JIJKCIQP598AA6A87A83LEG79A22EB91A7DABC9----1-11-14G646682332-2661--196DBC6B9611111111111111332375722552EDDEE111CACBBB77747894444447557DDE7444444444444D88CB---CD8BBCBCC9C5EACDBA559976CDB9D8C9ED433333B9588846966877867477345222112142233113222222-5463335111422244545555662222222222222344222444629523CCCCCAA4A3181117778212532441BB539-1-2---12-22B7AA66521222C7GLS8776868744444444445-66758685F75-9773677767996D787A9DAE9A89B66666666C3365744111111111111223222222222111117657458NM9EJHIIIIFBBB9HHIKDEEC7BJMYLGFK7DHHAC9AA9PEODLEAD9F6765622222225434BG9AL6J7GD38D8882D9DB8IG748788997D7232-2233241111111115999B78B9A9799688A8ACCA7CCBBB9CBBA9GB3-16D8E221222A897EB9BCDCBCACCB-DCBCCCCCCCDCCBBBBBCGHH7786698999999999999998CB9677C5288888888888722276566666559AF7B47755B6424435449888878574KFFEAEAHAHHAHA9GIEE666456546D789D99999CB7777777877778433443D7DD5455111111114-411111--12--------1--1-----1-1------9729 32-2CDG-aGC6CDEAAC9CDCCCEBAAAA869AA99858678AAC99CCDDIK98B7ABBBB9ABBA77BDBBABD9BFA98988A89CCBABA989896CBDIH2AVIdRTRROVKKKJNRJaaGqN**c3kT*EIJHXILVLJNLFDaDFaJQJOUGMGFokL7BACBLRQA9PKT*MMKRKYOVVBSLOLQLKKH * c.46 Rhodanese/Cell cycle control phosphatase
[ 139] 77977867999889887677677765558686567776666765766647777775577665656444 7874966988886667766-68667C666666A88887A96666777866657767763389767667A66656666666667655346677466651268676A778744444444444444677968767858888656666A976666645556668766667888867766667667676677556877AAA9A9AA99AAAAA686566AA9678A656555555AB4555555555555555444572635536232448855524542334455444435533344434333444444334333464433344456767A999998999A86556999776564645544745554558665543948BAAB56666A7BA9997AA9A977887888888-A9AAA89899958889BA9CA9A998988888BABB9A8BBBBBBBB9AAA998A5554533322564333443444444324379B89799A99A99A99A9999CCBH9999A9BACBCAC7999B88A897988B98AA887A8888999977899B99898669687867768788878A878678A87887677777668888888886755988A9EDB8BABBBADCCBBEBCCCBAAABBAB2-7B999321222DCDDACBDCCBDBCBEC-CDDDCDCCCDCBEDDDDDEFIGDDABAEEEFFFFEFFEFFFFEFCCBBBCF74EAAACBBABBBC3457666667777AB99E7774555555574569999988576C9CBBBBBCCBCBBABCBC4666566668AA9CBBBBBDBABAAAAABAAAAA99997493AA76665445455574644334-445333455425544244654566646667878 BD97GHD1cDA8ABDAADCIGDCDDDCBC99999CABCABACBDBACCAFBFFDBACCD9BAD99BA97888ABA89697CAA8BA8ABAHAADBE778888ADEF6EWJSDPIIPNDGCBDHDMIENBl*J4QNfBGBoKAEGD7DBBCFBCM9HCHQEGHCMHIBGEDN8CIFBEJD*FCCGCHLNZDNJEEHGCBH * c.51 Anticodon-binding domain-like
[ 140] -------1------------------------------------2---------1---------1--- 6AE2F46455556578877-6955687877769CDCCFKI79CCB66573376A6338337862D9BOOH554554651163757A6697891A573--9B877DB739--------------23344425455334444---73A78654733556769766743AACB161-22251-1244323222B49ABABCFBCBDCBEIA98A99CB9H665A655AAABBBB89A899988A9BBAB898799C4545647546999954756966C8B77687A7677555666566567987876778776867AA864585858A77777979964C76544367343A444355885529544457433671FBBB9CC9FFGLHLGEIHIFDGIIFHHGHFFGN-LIMJNiNMQPE5HHGMJMJMJMPMFJ878IJMHJGFEKHAAAAAAAA9EDCBBBC11--------115466356433534----5CDCC8DEBCKMJKPKNRCCDBOOLOEEEFAGJUMHKKK58KJIDDJJEMHDGE9CCI9B9DJF79788669AAIFGGCD8A6897C6CHD698CB8988DBBBBJBBE667483343555654556455644798NRCBBCCBDAADIJIHHFFHFFJBKFGEDD1-88C9B-2-222FJCFHIEERQGEIDNFG1UFGJGNOHJJSKKEEFFFHFGEFDEEGMNFHLKHKHHKNMKHJLEHDFEGEP3IHHIHHIGGMEE32BA77676AAAAEDF988788B8697669679FFIGHIBA9CCFIIKJFFEMEGGEFBOLH644344434AGJIFBDADDJEABCKINGJFIGEHIDDC52B999888822222222531-------------------------41344444441163 --1-674-411112343214431435222224433411121115552156-26322512221-----4-1112---3-121-----1112733A4B1213-I124321J9KA6C57CA9AA8B7IC7E5RaC1AAB586BCA8M8A8957CB8HB73C858639795OEE58C61--23122153LHVm2GV2JE3341 * d.2 Lysozyme-like
[ 141] 23223233322222432233333333333333333556555553334333434333333334633322 5574566666675755567-85445566666555556766566644655554555555335557747666555556556565474866777747-64225789699B5B-5655555-545558444444444445555755564779788A67888898879777877648544447455477766773977-AAAABAA9AAABBA667778ABA77797777777779A87777777777777777777-7878877777887788988776888888888887788888888888888888888888889B88888889AA8A9999999A9A9988AABBAA97779A7587595575877779479768999955555676666666666666666666666299878777676466656667666666AC6886777777866666666666669864444444455335555555556555323436767566678A8898A8888888898888788C9888878787A8CACCCAAA8BB99988CB89A99996768BAD698C8C77787775A89799A89EEEDID7897777777777676666666A778988DDBBCCG9EFCFIIIIJKKFFFHI1KJHKK4176778555555BAAAACCBBBBBBBBBB-BBBBBBBBBBBBBBBBBBBDCDAAAACBBBBBBBBBBBBBBBBDBBBABBB73CAAABAAAABBB446A5555587779AB9CCCCABB9BBAA9A9BBBBABAAABABDBBBBBBCBB2BBBBDFB555555555CFEEEDDDDDDDFDDEEDEDEECDC6666558888677655565555B6744445-545444344445434544477577656665976 JI89EFB1xNQBAAD77BA9777796798999A98887777779989BB89C798A77899989BAA979EDAB9DD99CAAA99A99A8G7779988964C8B8E59*MRCKCEHIDCB8FC9OLBHDZ*G1FFG9BB9GCCDD9DBBAD9AECBHDG6FFEIBJ7J98M79A8EPOV*RPQJGLKKW8NMXePILNM * d.265 Pseudouridine synthase
[ 142] 336194334553445477343424834A7C96354776797596949A57KII99AACA89323--11 8EJ5X6354454-1BBC77-7C449I777777DDFDCAKG8HDA6C666863EHC36522ABF9C8ARSJB44446553446C484BB86D72F655--6D5938AC3A11111112121111423124453372BEEIK443EDEBBD99899458564658879CFE6252322362322A9777CE5B9CGFGFGGJJEGIGHJIEIDDEAHGLABEGF67AABBA9Pa466666666666666334647553562512187227844423-66644375655544454443444465664656757454574426665CJBNLKKKKLHIKLJCPHHFMLKSDE25I76FBBBIED8EEFDFCDB988A7A8665-----54OHHA89DBCBC6747766555B1E8GA9ECCCC61LFFHEEGGFHBCEDA7367454677855555555555483F3422------11-11123-1--1111122223238538CC66IDGJFHABAA9CCGDDCCBBCEEDEEGA24DCBA8CA7AABABD47FA454931133333A988CC6CC64ADE9FDCCE9FHGBFFHDEGHHFFJ8E45354242432141111-114757BDE4479CCA7C68756663757556765787A1-1AA971-1111A8B9776AAA9A9AAD9-ABAB89AA9BA97AAAAAB9A9885689989999989999999A898A9AC6288A7ACBABAAB--26222226787A397533333313333234287788572338DDEBD8EHE579988ABA2221222123587B6657667567765656699A5555-1665433661111112262211111-11-212-11111-12111-8789B9A9B8F754 2533DI6-2-31cUPAAUHHDEC9G9E66555698B6979897988BAADCGGQILMFDBBB635433274375865347333346133D9FAUJF898E9MCYSj18EDVIHIQIMDA8BBIBGR8KAW*G3HII8AFAMBBM98DAAELD5RDEEGHAHSFUMRFRFIfEEF71163A25-X2G7GHNDF49MEHM6 * c.6 7-stranded beta/alpha barrel
[ 143] 655445445444444655566562IEGDHHKF2223322223822322223525455655546633AG 1-1-1----------------------------------1-1---1--1-1--1-2-------12--2---1----11----1-----------------1-----1----------------------------1-1------1-2--------1---1---------1---1---------------1-1222222322-2222221-2211222-111----------1----------------------------------------1---1----------------------------------------------11----------------1--------11--122-3-1-1-1----1----1-----------1--1-------------------1------21-1--------1---------------------------1----11--------------------------------1-------1----------------------1---------------------1--1----------------1--1-1---1----------2-------------------------1--------1-------1--1---------------------------------------------------------------------------------1-1--------1-------------------------------22-11-----------------------1------------------------------------------1---------------------------------------------------------------------------2-112---- BCHJYZQ5mIHIZdgOPQSQONPPUPSMOJPOONPMJONPLNPMNOIPNQRNVTPRROPPOPQRRPTRCKZYQMNZaQZaWOOPPQNPQUqWPdacSNQOMRPlwmEZuX********mw*z****u*q***2***q****v***q**t**wy*w****hsjpoltZ*hj*TwmdKbZO*MPLOX****S*jh*ZiWZO * a.74 Cyclin-like
[ 144] 11211232443542372------1HDC855F84213223D69524114-5D32-11214213251-38 78W3A486654355ACC44-4G22D7656766dAJEGETX2FOS3423533EC3D27232DIQ2F6GHGA63444FIE5468521321aPwZ2cB53--4M3F985DA552553322442222E232455442833334326AB5SGFH3611146H3J94456-3EEQ12421231B3144DB633234653BFFFIFGG9EMH8CD4797367BEB7DP464B23366639CF7A55976BBC7659C75E7766A58657AB98775C55429BEB88746345674588E9798C579B97AA766566DC664A7967D67DB767A99BF8BFEC43438482427JC6F7OGIB2B54353933464KR4584C42H69JATNGC792898887888589N-RILKHPHDIf94967P94VQ68EG7N666NAFEGEA8CCJJJJJJJJL79A5S372222222222Hh223322232222222222EFCC36935QCDHGDCR6666QOUeECBBCIEaO8Bhc29PKJHFBM8JKRBE9B9BF5495C56234235CBgAG5CT9768BCkBAB56A2BH7667J86867A7B5C525151162322321222A3446ED5FBFX5B7BAH5LPYOAFHOBGI7JAAI8B--59956------GBGC9IABVXMCLIQHB1VB9IHKPBJHWGGCB8CAAGRDRHSUBFF59AE6CFACHCE9GFEC6JLJ9E-GBA98DC9BF9G--5356646997C55848633482374556A86967BDD36CCC54DQB6D7GALLEGLUQD322225222DD96HAC7MBID7CED5QBPCHAABDBBA--435534442863--1-623-----121-13-------2-1-33221122121112M96 2332K33-R13132323223433636333122223224333332213323333233322222223422224222313-22222222122843354J222639234K-46E68979BE2222276873747l6-9554432332G73344244184644D35845P62624I44E323K2g44432633K34C439c358 * d.163 DNA breaking-rejoining enzymes
[ 145] 22211-23444444353312211-61163241-1----11-----1--11632--2-453-5221-11 NQQ3h566A9924157988-8811AA88887A5AAA99GE7A79CJG5BFF4CEB427--ABB8Q6CeZN7C9994DA2-1-842433MNXP3J443--9O5DETAMGE222222221111114676979888B9JNMED222L4NGI8CC465333466635529AADA243311242331GCC56CB36D9EEDDECDB9FEDCEDCGBB6DCECA9A66MIBCCBC78b73334332443334421153696168-2A3C99225823357377544465453444445454455532222333422224442214443D55EI6666666B68I7443EFDF3D8266E65AA5653E866ACCI415545JBB62222227AA8555AA7AA22222222224-88F77A898882A88BCC8ECCAB45B86753CBBB562222222227333559B222121211111222221132311331333543444645678856795777556A767754664774222556715111417A43383638622322222149874754626555A455755B646763D9989EH46342555555444575554465524222DCCB4E83F6B38657692766386394382-17315221111BH766B7ABBCBBABBA-9AABCACBCB9AA9BAAA8CFDA9574BB799AAAAB7ABA9AA8969AA9318BBBBBBB9CBA223311111455431C4C34367612213333344464532229M55654778A8887B676112112111569AF676769BCDA77JHIHIEEF44443255CC88BB33323223736----2--12-1--11132--2----5AA75B4BDC4U7B --24CBU-2132458QLKMPTUTUVTXA877684454766655877MMLPJONVPRKKHDEE44A36735429298A4F95765587AAGMJL9K9C9C94JC878-GTHwKWKSRMDGBGGMIYZEUDz*X1UNdCDECL9FRIEFDCAT9AWCIKKFMZ*DWQPETLZKIMFD6EFH*ACAIFaXpaPMW33HIFMC * b.71 Glycosyl hydrolase domain
[ 146] 557577877998888665878774A5585AD843357455555455645ABBB347567786554459 9892322211122254555-56--68555556866664552435441231-1223223--5522323553211111112342554544556525112--483B875496--------------1842235341682111111131AMH8CB745443547758A5799992622222622223232222453556566566366657654445565733333334433343524433333333343354443322222332232222222221122222222211222222222222222222222222222223222333234333444444444534326665254123234343435353333333222327444734444644443333444444244442235-4454444456618675887AB9AA647678746555B695555555576664344--------11222233222212222----18565667778ABBABA8766699CB767777A8D9CAC236765578875458456856347644444443348546785634437933223546575A623235924433434444334344444445564544AA4E7CA8FD9999997DA8888D8BA8AA1-38537111111CA787BBBBBBBBB9BB-BBCBBBBBCBBBBABBBBBDED8844AHEFFHFHGHHHGHGFHAA9ABABA52866666666676124734334444449778555434333334333555555557865DEDDCAEDCCDCBBCCD85654663559BA677777C989887666666654444212122333322222222322----1---1-1------1-------33323333331222 KGEKMMJ8yKJEKLKOLLKJLLLIJBKLLLJIHLNJGLKKHMMIJLIKLLLLHKHJMHKKHIHCJJKHCELJCIEJJFFJIIIHEEKKKHQLLLLOKJJJHJMPOMIMeJaTPRMQTGNQGLaNadFjK**m-gT*IJKLUJLVLMKNLJQHGXLNNPOOGGMPMLEPLLPGQPLOUOQ*OMJUPvXc*JwTVNPPLLM * b.38 Sm-like fold
[ 147] 1155-2AABBBCABB9-797677594553364442655555453356467C6B358576-55443-8A 9BD6E55644585573355-5955AG656667A7889CGD486D765559644784444466A698GC8B775556884695956A57ABC937554--8B89BB6C8A433333332222224867778876AA79979213ABB8A777756777876679878A8AD778666677666867985658987786879969C99BA9B99888788877DC7577778FD6666766666666668558795646956454AA558687757455544444435445555657555555555555555555574445556595575558665454A97756758662245665CC589557455666236865B99B66766A9JAA87777767AAAB9B9A9AB-88B89BA8AE86ECDCHIFCCFDECC9C9998DADDCB788888888A88788A84533355533111111111111111444459BB669CA99CDDCEDDCAAAEEBJCCCCBBFBFBEBA78BCCBCCEABED9CA88ABA89B86666666767BEA67A8688958855756B77B799ACCEEEE79765746555565555555557754577BAA9CBABJB9DCBCB9CABBBC9A99B896158B8A331222CCC9DB9GGHFGFGGGH-GFGGGFEGFHGFHFHGHHDEEDDD998FDDCEFDEFGEEFECEDEFGFFDFA7AAAAAAAAAAAA336977778AAA98BDBE777766555455558779888B889A9EGGE9EDEEEBFC9DCB877676677BB99B99999899DCBBCBBBCDDD6777669577BBAA22222121531------1---1-----11-------36434566357965 1111567-A63-657ADA6JFDBHMGHAC9ABB9876977666975D8BFEKUK69C7AAB9A9A585594677B874776A9B78894EM9D888A8848A94A9-8I3EBDCDBD8D77EBAIG5U7h*M1PCO9994DAAJ5AA987KA8D9D99CCMRBD989E87DHAA478A9z67577K7FI4VF48B5556 * c.30 PreATP-grasp domain
[ 148] 332433255555544454646445A344256937733345665AB59B77HED324224332418-98 5RF7b-13335322dWQHH-HT44SYIIIIILaXcXYXot5bEfDI452743DHB536--GFE2O8SOWV912222232258C657678976-933---24355C675411111111111111-1--32-1-241888AA1-199JDDAGG966887667768974HHD556565556565585A562156466666646746757775AA9585654659554433332E8133333333333332543221433453-31244-1552-31234442231111--11111211111112111111111122321212222297BDBCAABDB39466992222F3I1149542698A6432661112373637K77635324A8bQTFDFPKKOL5477577578C-ONSMPQNTHPD3RMKKRMNTRVNRKG8BA7HEB8BC9995455555575536IAD333222222211223222222222221223KLDF3DDBBEJMOUPKMDDFDLJQXFFFG9GTJZGYPJ35BCDGD978G7HCH67FB8879F53343444223BCEMHGDC6KF3GHDAD-OQNGIEOEFTRJSQRBG6455444544425222222245365689A7DDHJBFD68DAA9CB98779779796C1-25659------99B93A77888779887-687988798876988788BDIEEA5678886898988798867G667998732A66676666777222311221687655R79666146523324446A79884A446BDKMLLMLLKLJMJLBHFE3212112229998B99999FBDDGCA98998798322211D5DD98871121111151---1--------1-------------53122353334545 111-216-512166CFDGGIEJCMLQKBB7BCA8998989AA8BBCGDENINRMC9FC9C8987B6783784767G6876878899444CICD9GFA988689555-5K8H456683653356486276Gn718AH2856433453525563143555763568444C29E56833CA8*675CEIBLVEBCG56A885 * b.45 Split barrel-like
[ 149] --8111236213FIP7-31-1114-11---2--1133111--12233311L32-131-213-121111 6EE9VECCA9B979EEDFF-FJ66BJUIVVS9JJPLWdYg9LPTNICJACC8GHF7BB44QUI6dGahgd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d*K2RHZ6689F8CEA7D746C96JDFABD4556D6A5J55G44962123811253935I4322194862 * a.6 Putative DNA-binding domain
[ 150] 221---2-2222221222111111322121-1--1-------1-1---------11--1-12112--1 3482D346446353E7778-9C55EG77777ADABABCNO263674533632DEB76A--9BD4ABNFAA4----1111-43611--121---111---24313857412222222222232321111--1122154464---67326433356444332344627556322322324212273534---64266666777366676632432376722463642222227523333333333333343333211-11-----12--11132---1292223-1-2--1221211212232223333233322541113442-32-3111-1112111222----2----21---53-1411-21----31-216BAA622212A5MKN78BEBBEBBDCGCBEBCDF18AG57IBFAU91RKLGJJUOMPSNHD565ABN7677JET66666666A9A5227411--1------------------------25DG715EA5ANIKPMLHDDDBJJMPFFFF8GbNREGEC23EAAC8B77A9FAGK544-1238254343442-27B455441332231222-11122231222226A-11--11------11-------1-1-22363167383A734544454743336477395--12332------73444377777777766-7778776778777776776686442357664666665546446856777862-3545555355551--33434344451877A222-22212213113B9A994856384DEFEFFDD5CG8AA677211111111-122533233564565557B773442111-14-33432222222212----------111-11----1-1----------111-114-- 4456JB6-C752569aUrWzVec***oLNGMHMHJGEHIGGFHJKIfYQVfy**hfhbLOKOA786895965A8965365A9998A577m*iUokMBCB7FPKE9C3BhL*XQKNHNRRNPMPU*fKhF**h3gUoJSJKWPMcTHSNPOTMJUTOJJRPcaMbFbscgc*GGTL8IJF*BDDEEOUXrfTcGDQSGNL * d.16 FAD-linked reductases, C-terminal domain
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pDHFIAIEE977A899FG7I7P*B1HEO6895H79C74AA87D79G8GB678DG7C4A8898E96CBEKLJ*IGDEENEGO9FLGMIQCBJ * c.116 alpha/beta knot
[ 152] 4414-675767767644769787BC66747B6A86662535587848B4AFEB233222346778-23 49B7N43444434578888-8C669E888887CCDC9BLG6C9547464223466843--8764AACBDA72233222118674464366664845---3F56495926211111112111113CEEACB99CAA687BDKBFA6MFQLLHFIIDEGFHFFGDGEIEGLK253333363342896663338898989987A7B89879B866799878B79786212222C8455555565555555555662---32-1--1--44221---1-2113212----11-----------111111111111121111111114763DAAAA9B97A877553656A341-532I9SSGIF434IE33351-18C9977811111ADBDD555B769966556454555-99A8BB7B77518997CA9A98B8AD57778876788BB44444444B9956A6A11321111111111221122111111112429A5358689999B98DAAAAFFADBCCC8BAEABBDC48899F87BADBA9A7CABA798FA3333333346ADC4PaDEHNHEIFIHF1LEK7HCG69GIAG7JDU6346388777444444433475686AAA84585748879CDEC7D9ADBAB98DACE--189AD------7777882BAAABABABB-ABACBBABBBABBABBBBA8A988656A9AABAABABAAAAAA69899999116999899A98881113111114555B8A9722221332221422255555543457599BAA777B88B9A56552222322238A9D99999797AB6455556444334343D3335555--------221--------------1----------35723323338834 C956GDB-U9B7BC897997867BD8A6566779898777A56858C98B989G68B68A7A68A89B7A98B89783887BBA8B587BE87D5985866657989BLEqYbONiJGKFNDJGSUAdD**R-bQWGHF9OFMbFBNHIDKECNJXFGaENSE*SqCKEHGZmNGFLIB*AE8C8WEKR6IFE7IGAEE * a.1 Globin-like
[ 153] 996B7B777777887778BBA97A544533446678B989AB99857858686AGGFEEFF5555456 8773842222232346644-45225444444466554434344723324442335223217553356576421111224-2247576655532344111442356734511111111111111324323322452ECDCD213B5757B786676677787688799997755566655556879AA55356767888888798898799889A7986675753566664C55666666666666668777A724-55212348822663433246452343545455333333333332333223322223455223444447378444544575952555566436136783643664374656564335765655855656856884556455677677777777-67677976675487767865578767585997778778866666666555448783253333322332332222223222323464775437543766777B7888888977777787A676744766868558777866857565544433333675597B9A9A7878958775A998988B898B9BB593332244332323333332446553AA977897778679AAB99A799999A779672-4697833233378547756787688998-87688898789887767789B8554558677787777778677977666665287777776777722566566556567997A55545446656545553564446869799ABB9AB8999989AB3333342337779B7777799AA97777876778878735715544663334344455211214--13--12---33312144458345545562733 A855CF82Q89499EEDE9ABBCB9BBEDBFDFCCDDEDEDEFBBBDAACBFHHDCBDEBAA988676468678886586676876A98DKADDHK89899FBGCJ3BmFVfmXbfeLNLMORSrdOlP**d2kYxPNQLbOUcOIRRLKaKGlNcWRTGZQIHKPDQEEe9BMFENNM*HHFNKdhs*AzVJHHGEBM * b.122 PUA domain-like
[ 154] 22-13-41-------11---1125311-42421-2---41443--5-2-453816766664-833--3 498262322221-2724----3--25-----334443643231-1114-2217542-2--1-61126875-131133354BA512---8887-8-24--37465667-21------1-111113212122112716873456366B77322311222333453613A8A8142122-42222-1244224689RRTRTSTVJSQUUVX58GG7JVQV669J565666665TF333222343333333632342552332321266445448411-3222221---11-33333333333--------------112231111-A775888748763443DD58785B21463464CC4C-2496534514B76-6444811-1232IFF42CCFED99ACB9AB9BAG-767569657P4-PNN9JNLTVSPM88463EFCFDHGKLP777777772-1628CD----------2211221111211112-3-C34945DHFAGFKKKNIAADDCPOHEEGEFAFWED8DCF14BDD88A99C8HGFA6B9273BFC355544311277A57J1CD8889JGGC1949569332655755274464222223113-----1-2341111HF49D38877B7CCBA4698874575748A---25121-----77B98C778887A8877-867986668887677777BDGGCDC9BA7AAAECBDACBABAID65787874-GBCBDBBBBDDD113B12122466633JBK64737A163523-15KHHENBB38625GHDE9KHLA7967A3B73322132235ADDE9CBBCSDHEGDDA86873331111--37553433--------51-----------1--------------6515223212-742 A2CDHBG-OB46FGLCCGCDB99EAFABAAEEDAE9GCBCCAB9AA7FDGGFLKCGGDBHHGA663753B437875728959875779AFLGCKIHG9GFFDHRON2F*H*PWLHUIGDGBHOGWUGVBp*R-SJa7BCAJEFNHDHDBAJ8AREOJIJSUECFHD2PBDBIQLRJJLC*BHGEIXmv*E*cQNccYYR * f.39 Multidrug resistance efflux transporter EmrE
[ 155] 11---1------------2-1--12------2------------------5-1---------11-1-- IM*2322222222222233-322222323332222222232222222222222222232222422232222------------ABOHL4461-7---443HGBIeP*6J--------------2GBBBB989E7A966C9---66G6E565355994447544548888514222125-2216C9FF-1--444444444454544554466444455655444------834---------------11-----1--1------11-1----1-----------------------------------------------------------------------1----71-3-22-11---2--------J3*MDEI12112IUyvhVIKMFOONAAAAAAA9AAG2NfVIVbRbJL8-GDDBMHLQJIVWPX9D8jBPPRQNVIjMMMMMMMMJJKG8UC92222223222222233222222222222236PXA7GQOIYjqqqsiRNQQLrpigdgfbQexiqcqg*GYhbbqbLUTaeWXdJYOThGQILHCC977A7SWXZetK132-4664236653KJQBJKJ6-FJJIbw-3VDHHBJFIJBE99799A999QK6WhCDEC-CQSWAJJHFLKMLHLJIIIGJMOZGLT---ZKBb------32--3-222222222-2-222222222222322222-222-----2222222222222222L23-2222--544444344444---G-----AAAAXEc-7222332-----2--3-------KKGKPmmnmZehdPcabUa988---------GCDDRCCCCCNRLFGDB99FA9CCB1111DCX-LLFHGG--------1-------------------------------------GN79 64--222-B42-2223242322322234424442322222233222433222424222333322123322232234333322224222225322432232222335-2H294654711145-13692B48Z2-7831335533743324242461413821624343535A33534623k34344B67N35557A3446 * a.3 Cytochrome c
[ 156] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------1-------------------------------------------------------------1------------------------11-------------------------------------------1-----------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-1--------------------------------------------------------------------------------------------------------------------------------------------------- GB89eZc-*fU-WZmaghabdddhgihYYYZZZbbYbaXYXYaXaZaabdggpiZcfaYcbacUbSUXPYVWXZaaZTZZYYWYXYQOOZ*agcbfYbabcadzry-f*r*******jbujipo**f*f***2*u*Yohf*hn*gYonidqXS*mqnopXlhWiaYZ*bi*chrXVidh*hecYf*x**e*z*vppmky * f.42 Mitochondrial carrier
[ 157] ------------------------2----3-1-----12222172135-212-----1---------1 4CD-J1154442223DD99-9F11C7999998ECDCB88D38586721533-45612---7561O9DIJF7-------21216111-22311-311---13-436953533333333333333232245237443WYZYb---v-E8BC99655334554657A33AFB9233322232332112----126B5555555735656566577CA6552646734AAAAA956111111212211122122121----------------------111---1-----------------1-11-111111-1----------23213222222222222112222234113427332734421151132-1-4-51342-----54EECB465653A33323333321-C6C6735A44214998395679333871564558454B4222222223344-G89-----------------------------3126213644796676875554769E5555356765B7A22554C574695674388D858497111111144278F699353992EH997363452242844748*3681-12122111-1-------7337422B84586855758CA89797A77C6879D98--26567------46443434444444344-4444544444444444444566443345444544555444454544433341-724344534645---11111166568497C1112222111112226456526232B96666CFCCBBFDEDHFG32212222275649CBCCB698DC23BAAAA5541111--P6SSJKMN1111112233--------------------------32-22222222722 867BFFI1aE619BF9AEBCCCDEEDFAA7978ABAABABAAAAAA8ABDGDDJDEBBCBABDBA97958C9988AA59B97787A99BCNBAECD88A98ECRMQ-I*Dhx*qvvzdWSSaeb**U*a**y9*r*XXaZ*YbuZQfaSStWM*ZgdalOOdKeO*q***xNXLQ7NIB*EFDHIXfk*CxMcPRNVSO * c.13 SpoIIaa-like
[ 158] ------1111111111-12---121--1-11-112---111112-111-2331----1111111---- -221932533352232222-25--242222215434465425667774575556433555769254A9CE54333333222-1---11CB982C45---383776496D-------1-------32143312154-1113111416445463332211111132143441111111111111435----11-15555554636575542-11-1575---3323222221321111--11111111-211--4411221221211222211111122222224343223333443333333223333333323432223332-2112332333333322--133331111--2--1122-111----1-1256-C755743333343433224437455455554446-6755654378347776CD7CAB8742354663646665455555555344533461121111111353222233222332111114374344444777677455557767666645665756633664455555454734445634532222222334573845531221121112423--2-424464GC33322422222121211111112-123337825568586664444564454454464571-26334------44552323333333433-33333333333333333333333323335343433333434434233333321222222222222113222222333333A43111232211113112443343344442778756765666565552222222222666933333996779999999556333311211144661111111132-------12-111-111---12-222---11------737 9C56sDP-ZDF389HBCHGHEEBHELDBBBBAB99AAABABBAA7C9XDDGHLEDCGzDFDFIAD9984EABC9BDA6AB8DCJDD787GMJCDEFAAA9ALFHz*4L*q**sgl*UNKMGOOO**N*P**d5dZlKLNNXPO*RGROLG*KH*QVRY*KeQ*****RCBIFJ*JBS*G*HGFHFjjb*5qfBMWWXcI * d.151 DNase I-like
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cBRJMIMHQGDE99HFHJERE**M5PKSEDDELBGMD7EC99F9CQFJCCIGRgCKGHBKCIVGIFCCADD*CFDCBFIMPAIIFDKDFHC * a.27 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
[ 160] 777385657777776669545565B78A7A985332223222476356556644795355C8567-57 A8D5C566665556B77AA-A955AAA9AAA8AAAADBCD6E977664556599996722DAC5G9JGEF744444442334955554555727--2334A58777778-12-111-32----15565565685688899444B8B6C866965575555576967BDF8555566566566A5444554477BBBBB99B7BAA9ABA67787AA9AAA7843444444C94779798888887875555744-3443533-443334142143545222222255544444444444111111111111153455533326D8577776877776679943337873548785996C6669766555374B678779-22-265F9D566AA99D46554554459176A66B8C8H61A7779DF9BBAF8B8889B66877B8E5555555595665769--------1-111122121111111----468A756CC78CCCCDD9BBBA999FDDDE8DCDB9EA84677979ECDBADACB4595755984444444456757499586567875641767776995AABB9F7776666555554353433433756574498588CA4A566977897D776676A86981115666321223B8C87B89A999A9999-99999899A999989A888BBBA9DB8A9AAAAAAAAA9A9AAE98899898-C99989999999442622212555566D89555544144436564B9BAA8767566DEDDDEGFACCEA9DCE64434554468AA7898899887777777779DE77773464887765--------3-1--------1--------1----11-35765646864856 -1219BB-B54388CBFEDJFJGPPMGGF9BBAGHEBEDDFEF9CEEFEHLJVNFGEDABBBADABA99A788AAA7899A99899658DKAF9DIBBB86CBBEI-CzClEIEGDD75498A8SG3I4X*A-CBG5B87E67E96A743B64J7FA9GJLI9VD8EA6E8CQQAADGD*CBDHEUPaiHYOEGNNLLJ * c.79 Tryptophan synthase beta subunit-like PLP-dependent enzymes
[ 161] -----1-----------11-------------------------------1---1------------- ------1----------11-1-----1-111--111-----------------------------1--------------------------------------------------1-------------------------------1------------------3-----------------11-----------------------11-1--------------------------------------------------------------------------------------1---------------------1------------------------1--------------------2---------------2--------1--1------------------------------------------1---------------------------------------------------------------1----------------------------------------------------------------------------------------------1-----------------------1---------------1-------------------------------------------------------------------------1213-----------------1-----------------------1------1221--1----------------------------1--------------------------------------111--1---------------1-1111-------------1------------------------------1----- 1111yyi-2126NITBADABCCBDBCDCCBCCBABBCBBBBBBBCBEDDDFDHGDBFEGGGFGDCCDE6FGAFBDGH7FGCEEEBCDDDGNHAJJLEFFFEJFjip4u5b**********************a************z******t******e***hevY*TY*TtdW23212-2141ADJFCE422AB9C2 * a.116 GTPase activation domain, GAP
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w*Q2cUY9EDFPEHMKCMLAAMDAG9JFAEB9F8D8A6B89RBFM8BB8ByBBBDAMDJfAVHC9EHJF8 * c.97 Cytidine deaminase-like
[ 163] --111-1-----1--11242222161386563341--11121147556-1545-12112223332-32 25C2C1322341-323333-34223532333235552375-636731342323762-2--32E4555FA622333222-2243122-29CBB-4762--58258856-6I8DAD88333333334452322344256657-1-61994744545554424465747A665222222272222744641-588588888D9A6798DC843118187D414328C3333353663334342343333475564564666675564477774444444222223222323222322322223222233333323222242222518476222-11182534333444622452BB2-9851-314-1-311-384-78444-4444362454253633444244444444-974766526B7-766888A9E66A35222B3457764215555555544454534----------1111111121111111114-442645B8B8JFHGEE86777FFBD978848CLDIFCA--CA959CDC8D98J476G9B4783654446548AA7CD764344336233128996B956499F9IC56222222222225666555662313AAA88849264747756456677664A4664946127467---11-98756666666777766-666766667768766666685876664978879878789A888666677474358975988A565222413111444447656222263232232234AAA669967885EDBD7CEE7BBAA7DCE646145444466665557567884AABDCDD9CC66561--2554455----------3----2-1-3-----2-232-2122333622222222A22 4434UZ6-QI73897EDEEHFFEFEECFEDFDG998AB9B98ADDDCHGEGEEFDGHDIKHH6556552564575554765333645658F7D9689889887HGL4HsHPdejoobJGIEIWMmcDpP**m2oSuHPFHdOQRN9UIOHWJBeNPJNWBBD7CCFALDB9EIF88GC9z889P8****D**EPQbmdF * d.136 Phospholipase D/nuclease
[ 164] -----------------------4CHHB-645---4-15765645-4M-2214---1-21------17 7HE2C33444444468B99-9922A8999987888858896979I533512214413111BA7-K2AFCD621121222-535216221121-3------31-1425C322222222222222-2122-113131BAAFF321H2ICDMED322441222413632EER8111111111111686332146CBMMNMNFGKFJGLHIHCKEEFEJHK69CVAKG566657Y*333333333333333444243222332231344333323222323233332222--2121222222233333233333331--------19KJJvDDDDCHDEBIM6JJ3775XDD--H6A75cbIHB8CC7443AH223AA5DFF92222367jkp876RXQRf55555554554-PLOJJBOf493-OJJfRNPUVWBCeA9456443A436G54444444479866*Qa11111111--111-1111-111111-----27913CC988GIIIIDSBABBAANKGGGG7EKGUBKAL11GNNMGQHDS8BRH5DPIGA7ALF3333333765DTU9aWAQBNMEngVUT3rgmZVmcMPOIHOPK8E332111111161411111111512233TQ5DJIK9G99HJNOLBNLLKLHDEJLHXO--23758------GNTOCKCCDDBCBBDCB-DDCCCBBCADDBCBCCCCBBAAPR437DBCBDDDDDCDCDCBCF979BAAB3-FBDBEFFBDEED---411111222266VCW222222111111123321232-112EBKKNLRVTeIPRRSOQRW---------DFQTUQRRTSLLSfdBDKKMKL9A91---11aMBB78BA--------921-------------------------31856553441B-1 -------------12-1--11111111111111111--------1-----------111111------------------------------1------1-3------19------------------------------------------------2----1---------52----------8--4-----7---- * a.274 HAMP domain-like
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a*C2FBFA979K6CKDAB9AACA8F5JABLFNO8LAA6D9DFCEVI99D9*7777AKJNQ8IEBAEBDB9 * b.49 Domain of alpha and beta subunits of F1 ATP synthase-like
[ 166] -----------------------------1--1-----------1-11------1------------- GQw7*997776876FIHBD-BE33IOBABBBDLGFGLFPNDLDROQ445666F9A23811KIO3dDXemdD211121111C8B42444ceib1V761114N8GH*E*9s11111111112222132334433555HCCIE224TCV8A87777877776B89656I997957455659454595222442C9DPPPPPHLOBNMPMNODIFFFDOLQBABJH86433444kR444444434444444344235223333122133222231232222122223331111111121111111111111211111221112222COICPDDCIHJDHGDDAIG9887KJL32NACDAUSMCFDACA9A8D8733N1dPEEI4655579KGI7HAEDBNG6666666666C1GGMEHMFK8K73GFFDIHDHKJCFCGCA989AB9DDAA866666666466658IB2232222222334323343343443423538AFH49EDB9GIIKJGHDEECFFKIGGGF9DNFMCGCE44BBD8A6A9K8BBE59RA776EB44444445N579DD485234453864343675554746QLONh*39811111111131122111111312176576DBGHADA79AAAAABB7779879B89E2-3866923233364765776556655565-5665546466566666665666DC78655555555555555556546545633855555555555335C444446656359775555545555555555454457333KENOLNOUQRCKYJI9BCD2223222225688877777B9998IIC9D9A99A4444335589ABCD2232322254272G21-211112-11111--2111152555545446d46 11--12117-411412-2-123-12-2522-4422113244-1-1-34143-5--12-1244---111-1-2--211-111---211-2222-3251121221-23-133D38487443556A5CF374Up95D3I8455A457225711632769A793222484-323313342243B23134I8AI2A78865624 * a.177 Sigma2 domain of RNA polymerase sigma factors
[ 167] 11-1-12232223322-2121--11---2-111----1-11-1223111-311-1------233--11 31539668999777BDDBC-BC99DEBBBBBCCEDECDDG4A9GC78669A4BAA568337977C9BECF79888AAA4-163333333335-443---25222434231111111121111132232222224277787223A-A98566534554435454668587524222224222286744112221AAAAAABA3BABAB9352222BB9433825398898847-44333333333443433325A879976799BB9989566567544333A4447774444444444433333443344338554634445333482224221333124322226362-5432154223--2-12222344314677811111537764334642533233232224-8888985859719665BB5887776579524433227768888888846557343-----1121-11-----------------22632322223766767788876686788868758768513666775554565758663222531111111343453447234342523334323333442114166-531113111111-2-------11233333324535283353333252355343433531-3233411111155546457778777777-7788766777777777776776544646666665676666666554577772164444444444411331111122223672633334422332233355656452454233336665456655665112122-2121112221223433355888886663353-13255555511111111312--------------------1----132--121115211 6888EEF-sKK4DAKRSVRMQQOVRVPHHFGGGHJHFLIIEIJJHHSSLLQYUZMPNLIIIIFGKBHEAKJDHHGJKAGJBKMMMNGGGJdJSGJOFEGFDKMIDE1E*JQXXVaVaMKIIGNImlGjI**V4hUyIKLKXHLXKFOMFHRLFmJTLLOFILKMDMPgFNsZdHD9NOJ*LIMFLVNMWQTbdcdczie * c.60 Phosphoglycerate mutase-like
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n9-H8B4654765N44781565493554A6756A496E76C3577BAAB*CDC98KHKR5GEBAG8877 * d.66 Alpha-L RNA-binding motif
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wr*txaZgdgwd**Y*b***1***eZdb*XgvhbfcXSpbT*V*pkrISbXZWnNxUWhISbB47C9*B87DBXbn*AkU5669A98 * d.50 dsRBD-like
[ 170] ----------------------------------------------11-------1------------ --------------1------------------------2------------------------------------------------------------------------------------------------------------------------------1-1-----------------------------------11---------1---1---------------------------------1111111111111111-1--1-11211111111111111111111111111111111111111111111----------------------------1-----------------------------------------------------------------------11--1-1----1---------------------------------------------------------------------------1-----------------1----------------------------1----------1-2----------------------------1-11---1--------------------1----1----------------------------------------------------------------------------------------------------1-------------------------------1---1-1-----------------------1-----------------------------------11-11-------------------------------1---1--1------------------------------1---------- 4311geR-QBA4ACI878768777988888787777998878A9999A879A86A66676677574541453456543344655455666B57C585558868IFI4QfS**********************H***z********p******q******Zq**nrbX*bf*bx*Z2879e44446EIGR7JN43FGIKF * a.40 CH domain-like
[ 171] 1111111211111111121221112-123223112111111113113111122111111111111121 12214--43231---1111-12--121111111111-21122672212122-1313-1--333-3332232---------11211122-----1--1---2-214-311--------------111-1-----111111111131222122111--------11112122-------11---3432211-1222222244424444442222223442321223-11---2211111111111111111111----11-1-----11------11------1----------------------------------------11-1222222231211-221222122--311-1222-11221111111-11112331-1111113221112222222222222223-22222222251-4443444446331321112322622111111111111112212--------------11--------------1122112212132221-111122221111111122222-1333-1-12-12331-221--23--------11122211113122111--1-11112111212113221-----------1---------11111112111---21111111111121-1121-21---1111------111122-1221111111-211211111121111111111112---111111112111111211111111--111111111111---11211-11112111-111---1--------111111----1-22121-1-111121------------1-1-1-----1-----111111111-------1----11--------1-1-------------------------112131111111-1 33118B8-qOW2ff*BEJGEDEFCEBHFFDDADEFDEEDECEDCABDCGFEEGEBCJCCBIDA45456134496444133857545778JEJEFEOADEA5CCbiZ-3*rRDMGJMJADE99CEKIDE7Z*G5IEVA9ACJ6EH79CA87IE9ODKDFE983BE9D6CBD287AACJDJ*QMNZP****I***qGZMO6 * d.61 LigT-like
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b8H9A9E78PCBE8EBB8*988BFJENQ8I9FC87546 * c.84 Phosphoglucomutase, first 3 domains
[ 173] ------------------------------------------------1------------------- -----1------------------11-----1----------------------------------1-------------------------------------1--------------------------------------1-----------------------------------------------------------------------1----1------------11111111111111-------------1-------------------------------------------------------------1--------------------------------1----------------------------------1-----------------------1-----------1-111-----------------------------------------------11-----------------------------------------------------------------1------------------------------1----------------------1---------------------------------------------------------------11-----------------------------------------------------------------------------------------------1-11--------------------------------------1---------------------------------------------------------------------------------------------------------------- ----1-H--1-1ABDACCAE9A8E8BA9846577866A88688867A9BAFFB*6BBCBGGGAA989A5A889B867477689988434HI9CEES989A49Dhit-Y21*********wq*****j*****6***h*un*q***g*wvh*ua******epl***mf*hv*Tu*S1A42312-26****A*w366766- * a.38 HLH-like
[ 174] 112---21222221--111111--7331-1443151-23221-4734855548-1----21131---- 31143337557433522AA-AE22D2AAAAA7G7A96735-1432625633222B-22--426261734623233344216-313-233442-411---23233242431111111--------342334132-323365--1342C856872222-1----7924A943----111-1---253441234144434348433455743111344362113212655556321111211111111112211-974478438586622986145446553221111244212221111122211222112222221443222132344899787858538874463735213-13544736533-276732211316335-1--1564385165543233333332334-48426869437-3333323733365B1429-5665611422222222442-2444----------11------------------2523121---355444265665544677735678464922BC53438764264-637433253222221211555511422134351664-223334234577437631-22-2222231121-112111-223434522211222111111213222311-231---3428------23222421221112111-211111111121111111158521-2-3332333333233323411----1--433333333333--12-----12348-411----11-1111--11111111222254666836452333233231111-11-13---------1----3211211111------2444--12--------1-217223-112-11-1---11-1---111311132112453 C878LNL-fBA9HEKHGIKIJJFGKLLGGGGDJMHKIIFHFFGEEFJGJMPQYaJMMJJLJKD7B8BA1AE89AEBH3BF9CEDABDDCDQCGLDJDCCACDFSNS1IMZOn*o*twVSRUeeX**Q*X***D*o*LWTRqRaxcKbTOMqOK*XzahoMf*cKGRG*MMxPeJC9HHB*789DCZZe*JkRAAYeSWG * f.33 Calcium ATPase, transmembrane domain M
[ 175] ---------111---1-1---------------------------------1----1----------- --1-1---------------------------------------------------------------------------------------------------------------1-------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------1-1----------11---------------------------1---1---222-2-2----2-----211-11-----------2------------------------------------------111-25111135444433226666153412222--1-11-1--1---2--------1------------21----------1----1-1-11-1-----13---1----------1--------------1-1-12----2------2-----------1--1-11--------2-1111-111-22221----1--11-3121-----111111541-21121-1111-1-112------1--155555545654---1-----------212----1----------2212221---2-3333112222222-211122222222-31221111114322--1-2--222------------------------------------------------------1--------- ----FF*--1-133312321111122333121321223223111121211132623121121211211-21112111-33122122111321231122212-13142W-4y*********************6************z******v******u***mSRY*ce*m*VR-131J-11-262582623335341 * d.93 SH2-like
[ 176] ----2--11---112112-------------1------1---1-1----11----2--1-2----11- -----------11-32211-1---422222233111-222---11--------1-----------3-31---1111--1--1--------1-1112--111-1-2--11-111-1121-----1---------1-----2--12-211-23---------------1123-----------------1-1---------11-51---2--1----11--11-111----121---1-1--1------1-11-2---------11-11--------1------------1----------1111111111111111--------1-2-----1-----4111--1---111-1-1-1211-223-1-------112----11--121211----------1---1111---11--1-1----1-----------1----1-1-----1----------1--11-----2-1111---------1------1-1-2-----1----1223211------1-------111-21--1-----1-----1---------1----------111--11121----1--1-1-1-11--------1---1--2----2--------1---112------21-1--1---11-1-----1-----1--1-1-2-------1------11--211---1--2-11-111-------1-1--1-1------------------1------1----------2-1---1------------111111----1---11-2222331---1-2--1-11-2---21-31-1-1-1--1--211------11-11-1-2--11-------1----------1--2-------1---1-------------1----1-2-2---11-1- 2135WVP-NFH7POWKHLIHLMLKHIKGEFIFIIHJKMJMJLLGGJJGIIIJPLKKOJGJKMDCBDFF7BECBCCBBCFFAJJIBDHJJBQCHJJNBBBC9IIWWP1c4E********zun*****s*t***O***j*oy*t***j*swo*lg******b**ujZSPkXf*QtkY3886K89722MGMOLLF27BJID2 * a.238 BAR/IMD domain-like
[ 177] 11--------------------------------------------------1--------------- 1---11--11---11-------------------11-----1------------1--------------------------------------------------------------------------1---------------1---11--------1-------1-2----------------------------------------11-----11------------------------------------------------------------------------------------------------------------1111111-1----------------------------------------11-------1-----11--------------------------1-1---1-1----1------------1-----------1--1---------------------------------------111-----1-------------------------------1----1--1---1-------------------1-1-1-----------------------1--------------------------------2----------------------------1---------------------------------1-----------------------1----------1----------------------------------------------------------------------1---------------------------------1--------------------1--------------------------------------------------------- HFCJdfZ7yJNDWRYUXbTSUUUSWTVSSSTPQUTUQUTUSUVQORRUUVUSVUSUTVUQPQQJKIJKBJIFIJJKNCKKJHJIIJIJJNiPXSRSPMOSKPMTVY9X*f******uoitmnzn**e*j***3***kmjo*ip*kbppkhtnn*k*qpyhpfgyreX*cizUdygLSSN*JNMZUpq**T*kNPOURRQ * d.20 UBC-like
[ 178] 11----------------------1----1-1-------------3--1-1-------1--------- 2582G533445213EGGPP-PGAAV9POPPPEIGFGA7AA1T9P2123122132323411KH62i3Nh8f333332221233123222766615336--46245823361111111111111133336543333443345222R246C655B22111111112218DAV41111111111111213332233A44545555755565533228755733453-111111173211111111111111311311112222212111222312211121233311111321111111111111111111111111112221111322444444444444A4883333433-25322222222332323342333525855311111ACE796467A55644444444443-88I8AD9858217558348455546E452536232253411111111443216442212122222112233237333333212412284134423AAAA9GGEFFBCCABHIHH6GBA9BDA924799A8654878B6767B21139522232234454676642243533322212326349357888UI15-112211111112111221122324328725564474578979776976776667661-25545111---A264462477A4AA744-75455554667754444445466375446444444444444444444445411455555455454111323324CCEE36D23333343211122--2667765842385565689564455556473111111113455D4335356744333333322222221123AA4455--------212-------------------------24322333331714 64AB**9-H44-889KPiHdSVcntsWCBDEDENVHJRJRIMMDDFQURbaSaiKQbcMKJLEDA78A4BC7A7BAA7AB9BDDHGAAC8I7P7BA56346SAB981CnC*IPLPRNHDCCDOGPPFZH**O-TKkADEBPGIOEBHEC9KE8RGRJMGBEUGJM9LHAHMNMKO6BD9mBCACGKOHyeLIAEEFDCH * c.19 FabD/lysophospholipase-like
[ 179] 5584844554445553464455444444454443454344554445445554548AB8A9A5448-56 7A97766799977787766-686688666668C8887BCB6787766666669887892295K687FA676866666667IA95766666665555322484698974C-------11-----277666756567799785559789A788A67779997797996B89A868769A67787A6677674768CCCCCDF9CABDCBB779969DD867688787778668E488888888A8888AAB978B7A6556866699777795B686DBC778566668666666666667666666666666666666666667976C9A9AAAA99876668666777A57968678678868A988C6747567EBBF6644766DBF777778887776777777E1886899789788DAA89ABABE9B77565A99686697G66666666668678954424444411---1----1------4263688A989BB86LDDCBIDA999BBNQCCCC8CEEPBFC97598DA8D65B6D9FA9687678A7555555576767848A76787C7466659797777689A99AD6B69B6777777649444444469776779785668A4657666686D6668768B86832965475435559AB9B789779997977-77979997977777777776669A667B9BBB9BBBBBBBBBBB55575776355755655555534496656665567786A44444445535422499999896B66798899DCDA9BB9A9987555554554798E6666666A675455555444544446686688764444444483-1-1---125-2-1---1252-----59B9A595655745 23-1433-E88333655725565736976444474455553555555678797A45554454456674466456845-77544464647675556477757759DC-5B497A89AC5554653BA355ET6-B874665447644563554384563A4AA3F953155953744444*66654F7AI5663486566 * c.78 ATC-like
[ 180] ------------------------1--1----1---1-------1-1-------1------------- ---1---1--------------------------111-------1-1-----------------2-2--------------11-----112-----1-------1-1------------1111-----1----------------11---------------1---------------------------------------1------------1-----------------------------------------------------------------------------------------------------------11-1------------------------1----------------------2-----------1------11-----------------------1-----------------------1-----11111111-1---------1------5------------------------------------------1----------1-----1--------1---2---------------1--------111--------1--------1--------------------------------------1--------1---1---1111-1--1------1--------------------1-1--------------1-------1----------------------------------------------------------------------------1-----------1------111-111--1-1------------------------------------------11----------------------------------------------11------ 7C44*zY-L892PMX9AHCHHGDIHFIFFCDDDDDCCFCDGDEDDDEHFFIJKLCJHHCEECBAABAA4ABA9AC9B6BABBBBA9CAAFOFAHGHDCACBCBIKM4lms********uxc**u**i*z***6***d*yy*x**ua*xxq*uW***z**Z**goqfd*g*tOQ*g6AEB*98979cm**GvNCAIJMKG * d.109 Gelsolin-like
[ 181] -------------------------------------------------------2----1------- 1121111311111113222-2311222222221111323112311212211---1-111133-12431211111121112121-11--1111-1--1--1-112111111------11111111111111111121112211-213121122212211111213211233111121-11--1--1111111213333342423333351111-13332111112211111212--1111-1111-11---2-2----1--2--11--1--11--1-4111-1-111--11---11-111112212-12--1-----------12-11211211113122111---111-121--22-212111119B111--113111111111213111111111211111111118-21211411111131121111111311111221111111111111111111111112222222211121111111111111-1--11111111112123351111111121111111124111111111111211221121221111111111111111121112116141111111131222351211132131111111111111111111111111111112111111111221111211111111111-1111111111111111111111222181-11111141G81111111111111111111111111111111111222221221122212212111111111111111111211111111211121211222-2111115122221322341211411111111111111121111141111211111111111-11111111111--------1--1--1---------111----1----12122111211-1- 3445vJb-SBCALLN69BAFDDCBCGEBC9BCDCBCBDBCBBD987DtCB9AB888F*BEEDK4678542456769B699575624989CBG9GCM8C9B5GAEU*2E*H**xj**recVUcld**U*W***B*u*VeWT*Wj*VLfeUS*Ta*Vub**Y****eQ*qPZ*CD*RERyZ*CGCRHQaRW8STYVRXcfe * a.140 LEM/SAP HeH motif
[ 182] 33424555555555555733333132232423336556333433224323232434353425343-44 9B85C42333423234333-33225B333332687834A966637D443645B4A22A2298557BFBEC533334337323644444437423432--36554A875633333333334433444555655456555982334765374455355444344473334683453433623429874487623A445465666566566DA88B85557597957DHHEECC54888888888AA888B6689J963BB33A3ADB22CG54B347CBE3335444433544555454544444444444444468222766A472AUAAABACA8B63H44475656573836322232224322759366574446643333332868645534568888888788F-666786679J52F99AAADDBDJK845535AB88797A8444444447775455511----------1111111111111111142553577777HFGHGHBEEEDFEGFGHGGCFIIGBDD94499A84766C6AAAC55456568577667662435443864344535554565658544645534674655453666574434444445554545597B86684A6877666655777666556562-44543321333JE9BCFBDDDHDHGGCC-DECDGFICDDDGDEDDEEDMILBBABHHMFDGGGIKFHDKDEGIC9BBBBB73DFFEGFFFFFGF3364777675445749C87786877787598983334343343B6A9A89DAA89788688866666666649BACAAABA9C9CE6744444444444433576655551112111122311114-4243711333162132---3A6535E5558A34 3423478-C43255564545585685B5545445443333344333467446697576479855343413424434334334334432247F432343234733562657DKDCHGG9A94AC8QI8K7X*H3E9T5856D6AB96D8A7C64G9D9BDAHK7E496C46I47E55492c53344HA9L69J9C92447 * c.80 SIS domain
[ 183] --1--------------------Hf87G6IHW--C-------1**2h*5MrPV------2----1-1- BPd-53--112----21----211-1------221233631-38A11--11--13-----118-82BHA56---------829136128775-711---2E193KMPUB1-1-11---------7457A12DQZ2PKJMIKACL6rPh*KK4CFEE233422COFAow*D34A944444994N241-2124353332323344343441266644546466155-111-1HA-11111-1--111-------1--1--1-----1-------------111----1-----1---1----------------11111-11112E24H1112122426-743111-2-3--65183BCHC7Q3A4332621--H4LCBBB23342B6POTC63PMHFN33333333335-nhgnbPtxAGF3EEELMHMGSLGIE575D362D9CF8522222222251153dKN111------------------1---2-21-5583133314E8AC9975445CBJN566513ACHBGE412CCCSFM9AJHHQ95ABP96FFOB111111123DKRh8*YPHMsb8*niey1ud*bNcZNi78E8QpUp4-11-1-1111---------67-3A11E93A7AA8A7DDAB9ACB9BCB8C9BA8BE--17CFD------55562635556566664-46557355844555554543332212-3333233333333333635222361-C23565444566---611111465565I4A111----111-1---333331--1-5DJKKJGLOLCGGJGMLHH-----1---D223189889887BCABJKKLIAAB2323-1Y-NNBCJJ1---11------------------------------22--211112-P14 ----52--2111--G47B81343-3-111--1212---------1-4834765A4673243421-11112-1-2-11-112-----2121127-32---2423333-171224457311-11224411-5H41416412122121-21211223121172--1323-312831722131-1-2-6D94Q87431HGRK3 * f.55 Photosystem II antenna protein-like
[ 184] 4444434666666656544444448447686734422222224A444666C88222244434444244 2323213334343422233-33223533333332222453376721331111222322112222423221111111112133221-11-1-222111221222221-313444444565666662221222222244444222244444444443334434344366464444344444434121222222222222212222222222222222222222222222222222222222222222222222232222222222222222222222222222222222211111111111222222222222222222222222223222222222222222222222222222342A44422244222221221511141222244A68365444442222222222214466462268125222758872A944322222624621111111111433112211111111111--112211111211211112422523111354666542222442344444554923422266224222242424221222454333333322236211111232324232221212222244454463222222222121122222222-21122222121222261222222211112122222222212221211122222222223232422-2222222222222222222121222221111111111111111222222222222222222222222222222222216222211122222222222222224222213222222111122222111122222222221124444423254232212222233231222112222222222221322222-------21-----21-----22122222221322 JLIIWXIIzNOJLKJHJJJIIHIGIEHIHHIGIIIJJIIIJIHIIHJLJIJJLIJJJKIHIIJJJIJJBKJEJGJKKBKKJJJKJJHIIIQJJJILIIIIJJILRWFHUVeQlOMRMOMNISTLakK*B**j4aaqNFKJmJPhNLONMPSLNdJOLLLPeeJOKMJhKMhHOXNPMNJ*PLKLLsYrwIgVJKKKLKQ * a.129 GroEL equatorial domain-like
[ 185] -------------------------33L-1-------------1-----------1--1--------- 3--28-----------------------------------2----2--2---2-------43--1--194--------------------------------3-5--------------------------------------8-----------------------2------------------------11111121211211214311--118----1--33333344-------------------------------------------111-----------------------------------------------26666666626-1-------31--------51----------------------------------------------------------------------------11--------------------------1------------------------------------------222226-2222----2222222-1--------1--2--1-2----------A------------------------------------------23-1-------1----2--------1-----75--15--1-2-55562-32221-322--8-------------3311-1112211111-1-11---11---11-11111------11-22112222222221113-------2-311131111333---------------C---------------------1------8113111--------112945256424-4DE999998HA5BB11--------------------------------1--------------------------------------- 671189Y-YCC2BAG8DEA8B9BDB99BBACBCB9B9DAD9DDCABCBCBDCHFDCHAACC986788829998AA99588989779BCEEJIDQIHEBB8D9DHJU1W*F******usimlq*o**a*f***P***khYu*iy*tk*lxo*le*q*txmXniRYVUSzXfwOfTM2ILLSHIF9CREOF9KFYds***x * b.72 WW domain-like
[ 186] -------------------------------------------------------------------- --------------------------------1-------------------------------------------------------------------------------------------1---------------------------------1------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 3223412-2-1-----------------------------------------------------1-1-------1---------1---1-----------1------21D*******xruiw*t****v***3***t*s******U*mbh*fZ*x****ARMV**F9GCAF7A**-**-2---x------11----11E * d.170 SRCR-like
[ 187] ------------------1--------1--------------1--------1-----1---------- -1--1---------------------------1-----------1---------------1---1-----------------1---1---21--------2--12--1---------------1--------------12---------11---11-------------1-------1---------1-------------------------------------------1-------------------1-----------------------------------------------------------------------1-------1--------------------------1------1121---------------21-----------11111111111----------11-1---11-1-1---11--------------------------------------1-------------------------------------------1------------------------------------------------------------------1-1---------------------------11111-1--------1----------------------------------1---------------1---------------------------------------------------------------------------1------1--------------------------------1-------1---------1-----------------------------------111--------------------------------1----------1----------------- 2312112-31111-3-14-111212121232-11-12----11-1-11231342112-----11-1---121--11-111---113--112213111111221111-232********vw******z*****6******u*****m**wr**i******McOc**EDNEHKDH**1--271-1--1231252--13-32 * a.77 DEATH domain
[ 188] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----32------EFH**************szu****q*p*n**nol****************eqxPfcEdQNvVrWWIXZWfnmltGBIZng*d*uyw*jKO*VjQ-AM*----------1-11----113--2--111----------121----------------------------------1J-*--13----- * g.38 Zn2/Cys6 DNA-binding domain
[ 189] ED428CHHSRQROQRQH4GE775Q989B8HB534448443443A347K436455JFBOeA74448463 EAH57312222311345hg-h72235ifigi25656533356E765282232343112115443444535211113222273242841332213233--1114112F8322222222222222322L45A24H222788B11154EPGLDHl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kBCCBDJAIEA68RAUNLFJLKFBDDAFCKKEPCf*K6OFQADDAFBDJBCFDDCFEAOADGFHDAGAMHJCDEEH8JP989BCgAB8DBPBGHDIG8CDBBG8 * c.120 PIN domain-like
[ 190] 11-2--2222222223-3242222422443364333322222223346335653321-1113113-22 6594333333433467644-432246444442466655B823355432343335433211544224763333333333246564444466974633-1257345665561111111112111145554444646444454433637776666455544544447454464444455545445674443345576666666675756678687765586586644555555453555555555555556556632223324322332222222342443222212244423334333333222223222222245444444424855577677777766855454343553A55436743455774677553574A766746556A7F9A6599B98967666565658-8CD89G888784988678FB9ACB86556B8DD8BDA6966666666BA95696844335333431123342332232232222658654CCBA9DEFGECC8789EEBD888859CBJDEHB4688ACA9BBDBAEEC88B5745865555555665AAB44557567546666299A676775898879875635556555346343544555455667696789467566666677788667766862136B761221128699676999C9CA988-99889978989A899899A9BB896869788888898888889788866695277777777777733344444376885C876333648233325656888884656777AA9A78688877789984343343335566655555655555565555766666644433445551111111121121112-312224333322222222245633645554653 3311446-A422456AB7AACCBCDDD9996888B97998789856678CCADB8B7B968666897757B7896886778777883696CFBB7A96855E8BCA1978ICLBCJH76959C9B87F6h*D2KBW6869G7BCD79877C78DB88AC8DBCDAH8P99HAFH858B3e32467OJOV7T85499B96 * c.77 Isocitrate/Isopropylmalate dehydrogenase-like
[ 191] ----111111111111-222222-1--4---------------21-13-------------1--1--- 13B3F3333333335DD99-9533F5898889678793E84FCJ4763634887B333334454434CB84555555433373-----1172-311-----1--2-1-1222222222222223--------4--DDDQT---E3dFFNEDBAA22-1-1119BM6FDDG-------3----2-1--11-------------------2211-1-----121--------43-22222222222222---------------------1--11-1----------1------------------------------------1115311111213112111111121411-141-22222----2111---53-B----------2111----------------------1--2--12--21121213221-11-1-1312341--2--------2--------------------1--------------2--121-122-233322312332-173333312215534------45523435353228-231------------86693-44----1-1111---2---1-HHDHq*-4-1----1-----1----------1---121-1A211--11-1-11-----1-----3--1-2-7-------1-21-2-11--11111-1--11-1111112-----1---3232111213212232222121---11-11-233343213343--13--------1--9-1----1----------111111111117332311115111-2221-22221222-2121111113321111437335541131--2-112211------------------------------------------------2- 5778OLH-XEE7CBLBACABABBB9BADEDGHICEBCDADC8BC9BD9DFDCHDDDEDDEDBA8BCBD69EB9AAEGCFGB9AB9B897CJCAABFC8A9778JMN1K*C*******gVbZgeb**U*Z***C*v*UabVtXkuhOlaTQxYT*dwagqOmwNcZSLpOOYGUYO3GFHfCFBFCJKWSDNB98NPNMI * b.26 SMAD/FHA domain
[ 192] 33112243344444851465553376664467232111111122332334545133233224553133 4485A34766734374444-46335844444476666DNO488D46583224A9944522979769BB8963333333433682233256553544621476764355734444443333333333244223343555662234545545543333333333443466552323222333238985533386B8888877767678777B99997787887754666666674444544544444444444562225621132882274342433434444443344333333333333444444444444443333333343735455554454454577443545434845235633445743557433553676675565564D875443333378787787778-65B44D468643977586B96A7868566568555577B444444444443456533334333333333333333333334434468B7377786B899AB9777899AD7778678AB7A9723776D65677AA5B5465354545464555544364585735545444564296956785455556C55445443333343433333334445533A97964A777867676668666666767672-4865523222275757768887888888-8889988898888888889BCA66666978799999998987977878788517888788687772346555559A9A865774345754666555566666657665A68888899BABBAA68886555555555455755554555565555555555444433443322331111111141311121-111-111---111111---34523434444744 3432778-G6564578BAC9EECFEFE8887789767998898777B99AEFEE9BA9AAAB8896874877889884989677766888HBB7AD8888A77GCI14DBCEHEJJC9999A99DA9P7c*C-IEDA896D78E978B99A99E8CABA56A7A758M8CL66766D98*888BDMJVX9JI89FTACB * c.58 Aminoacid dehydrogenase-like, N-terminal domain
[ 193] ------------------------1--11111-1-------1-------------------------- 1431123333321322122-23112222222333333132111212111111232122--1131311233311111122122111212112211111--11111112111111111111111111111112211111122111113222222121121211122111121-111---1-11-21111--111111111111111111121111111111121111111111121212111221112211111221211212221111221111111211141111111111111111111111111111111211111111111131333333323221112222111111112112111311111111112113122111111111112111111111111111121-12112111212122211132112112223211233311111111111111111211111111111111111111111111111111112122211122121211111121211111213111211111112111121211112112121111111211115222112421224111222312233323441211111111111111111111111211211211121221122113135212312212231-11311-1-11112111212222222222-2222223222232222222111111112122222222222222121222221-111111111111--211111111212-211111111211111111111121111111112121221221111311111111113122112122112111131211111111111311111111111111113111111-111111111111112111111111111111211 4358gnN-XAG5LJQRMNKNONOMOJMNNNOMOONPKPNPNNOLIIMLSPOMSRcSMLPKPQJEGHEF6FIHIHGAC5CDEIHJHIOKLIUJMPOSLHJL9GGKGD8cbg*fpfjlqaVTWbiW**Q*S***9*v*ZUWaqQcqQVfaXNpSUzNibcdSmhVicjKgOGhLpbfCGML*HLLR9TafkNVS9IJWLN8 * c.15 BRCT domain
[ 194] --2111----------1------21--123--211111111111422233233156434641223133 14129114335112B9978-79--AE767778BDDDIEXS45272114-11-846332--9542575B7521222111213212222123333333---432363153122222222222222333445344524---1-222213213221111111111112122221111111111111--1--222-26333333432343334434445333133442311111123222222222222222322242--1--11---------11---11111111---21122222222221-------------211111111-23158555655685823334665252412223322543222344431221126433------4696D31475576223323313321A8A78E7C142-422121643367A7---237211224944444444511242211111111111----11--1------1-11-218324A77C956A6A6566699BF6666-9G8IDHIH2297778253C684DF2846735524565555231BD513334436334444153432353444547633-------------1---------1-5587859484878877764787886779B69B2-1341621122255564567665755577-6778755767657667667AAA675677677677677677776766666663168888888888822241111145554569A224323111111111CECDE77355B5DDDDDCABCFGEEA787311111111269986666678788557787734422222132442222--------211------------------1------42332222225312 33239A9-YFH477JSRTHSUULXdXMGGIGFEFJGHCCB8FCFHGMJQTggjjTaTMKMLOICC9BC6FBABBDCF7BGBKNLFT8DAHRLRCIAFBD98BFJCI28dLRCJ8BEJBBDAEEAQICLFl*G-OIM7FDAIGDE8AFFB6HC9bEEBDF6HX7GBN9GCDO9DBCBDDA*CBBDHQQjmRYNJEWNPTI * c.25 Ferredoxin reductase-like, C-terminal NADP-linked domain
[ 195] 44434375887887874577765443332433425335667775334325446277577774564-22 79C5C34444453486777-7644AB7677779ABA8AJG8AAC57866553EAC66844BBD799FCEA64333333655784645488785666233666869666844444445445555445365646586ABB874455646464374344222323453666754322442432236657755464677777677578777789667677679A65747888777755555555555555556665422-22-41-3562221151232554343223313343344343545222222222222232222233347CA9C66666666677966433365833955754465787A7A97A795576586684444488EAB657AACBC77776676679-76B77C677943866466B976A97D66698988AB789888888888994498933333333331122222222222223333569L7498768DCCBCCC888999CF99996BB8F9ED8456679856678ADC8449653346333333334598949C897764676665DBDABCFBBA9CA558B44454333444334434333455556676B554666467866666766657667598413784543244486866765667577755-65555765556755555579BA75664876777777777777764455555446656666566663445666556666636555555544333344447777745444A47777686A676765867444444444355575555566677886666666644443374444455--------43211112-2-2333222222322211177665686766755 55-1956-F56335656767795898B5544445548445455444777978EA7866677764534224444644515544434453488666697676543A8926B6DAF98796556885GE4B5R*A3CAM5644957B538766973E5677A6CN5A763N95Y469666A6*66677HBOJ6EE68C8776 * c.48 TK C-terminal domain-like
[ 196] ------------------------1------------------------------------------- --------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-------------------------------------------------------------------------- 5323XWC-I54-C9M78IEGGJEFEDHFH8CBB8AA9DABADEDDDDFBBECND8ADEDC9A6A646625A47AA56-45588678344BpL8EPD96869A4BNB-8I5********x*gy****x*****O***u**q*****Y**vk**U*w****OXYUoZNn*l*iS*Z82947G43358R*q*H*G24DDDD3 * b.8 TRAF domain-like
[ 197] 22222432222222432243467312223432113343222223425333434244364421116232 2132463322233311222-21112322222233332112221232143321231111113233434234235554446264314424556625222--2613231231211111131211113222323323443334232326423-212453311121122331235111122211132134333244313344433444443353333134342312233555565353333333333333333461232245534251553355352333444555666756665455555655666666666676656644466663A669665667686758559774A554334323885B6244433222335244211411111323245433A33644444444443-553572323361544455445534433247374344334111111113231336822121221311111111111111111111111215234264334332555555456666462847578229773458544672353234345422222222113254A7474685567643241442342222243424333211111221111112133343338664514221536555556354545565741-3341311-22297677979CBA9DDB9A-8999AAC9C99BAAA9AAA8B97774898A8A8A988899888898A999833755655566555121323232222262322667566556656555111111211232455432522222262431111111111677755555897772321111223121211123322541111--1-31311121---11-12111112111---31322334332352 B93588K-mGLBJGG47758768BA6A8896566663BC9DDD688C646796A67988766866585254466675494646496B449BA7B5B655B585B9A66JL*GNKLLYHIIJINMVSGdJ**T8bKsINGETLNTGFLNJHdGEdJRHPOV**NNTMGQJK*BHXN4NUI*869C9SFISCJMBHWURWV * c.7 PFL-like glycyl radical enzymes
[ 198] 33335343344433448343434564455955657457455546559457468634333333332634 5762334444433345444-463356444444655593633336333433433633233347445436444444433333543444554453254433437563555363433434443555553434B3454333447522654585545544675544555446657665565554564443334343332333334221223522332232222222432423422222234332222244323243235322222332222223332223232233322322223335222233322222222223222222232222223439A9BE967A82598D544273353242242234223233226595736454433234549544364533422222223222354245245643333334453445543343343346433322222222423254532232222243332333333423332545526453334444444435734445544454433433474333336547435544344464343433333333343643434434333545453232551754633585447-1415654356545656464454734554238333325546534444334333347334335434333343534464544453443-44444443344454444435435433444445645545565444444554434333333333343335333334434644734343333433333433554354343443333343343643434344222222123653534444553964D343444333434336A4444456665565433322233-36973427736572439A443588636653534 **FNRUB7hAC9DEC9CHEADFDFBEHDDBHFICD9B8C8AB999BC7BHCABD8BBC8AFB8CB6A71AB9CA9C95B89CB98D789CH9CGGL9C897OBC9K7GMKdISROOO98B97B7JKCI9q*D1IFG8A88E7AJD9CCA9G98GCMBBG9PiTIZcQD7AjFKQGABFA*BABGE*TLiIRW9CMKKHD * e.29 beta and beta-prime subunits of DNA dependent RNA-polymerase
[ 199] 22313221232322242311311216522122222112222233213222331111112232224123 1493B522222333B7866-6A118B666667999987CD297564344454855545339AA4A8C9AE52111122-4A524234333232267---24354256312222222-1111111321123133436669611246655645432442-111122334715-22-1-22-1--13211--2223444447853456875974434568121452245553333144444444544445543324-4122131-1221112434-12312111111121-231222222222222222222122122---2222-5132666667616334551322111224221-3311-22-21555-12152477762111165736342342363343333334B-44322423465164467774566634643434342343932333333333132341111111122--1122111111111211114443233334656674444435547555524A485976-1333312124362333312222751------222214342-14543495453446235544434495232533222222413111111124221326457412456175454445444444444731-2333321-11134441352334254532-33232243433533323344464365133233333343333338333112321644444344444222522222566643966-----1-1--1---187877621424279A7C9A7859768778-3421321313325666663556444423322222222--122223223332313222--1121--23122112223342111---411111--2533 5324A9P1S97867C97F6CACACCCB87A7778A4A878767676537EB9HIC7CB4A797446333544555653456235685734A4777D6566697B9B1ANB*RQYVd*NHOMOjO**MfP**b1iUqJTJLcNNbQFQSJCVNJ*GQGm*AOHITL8EL88JECdECMJB*EKCVGHEGN4CCBFCAA9P * d.126 Pentein, beta/alpha-propeller
[ 200] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------W****rOY********F************r**UT****PB1A*---------------------------------------- * a.212 KRAB domain (Kruppel-associated box)
[ 201] --2--------------1------------1--------21--------------------------- ---------------------------1------------------------------------1--------------------1--1-1--------------1--1--------------1-----------111---------------------------------------------------------------1-------------------1---------------------------------------------------1-------1122-22-----------1111111-11111-----------------------------1---------1---------------1-------------------11------------------------------------1---1-----------------------------------------------1----------1--------------------------------------------------------------------------------------------------1----------1-------------1----------------------1---------1-------------1---------------------------------------------------------------------1----------------------------------------------------------------------------------------------------1--------1-1-----------------11-------------------1---1-------------------------1---- 1---omJ-411-KGK657B797877788758877765766566887666876A588697767866667447243676476535455A98EPF5LIKIGJFCEFYaY2Y6Wz*********v*****x*****P***r**w****vm**um*wl******QeppgXUP*WY*LocS1-1-7-111-1-2-7112124753 * a.87 DBL homology domain (DH-domain)
[ 202] -----------------------------1--1----------------------------1------ --------------------------------------------------------------1----1-----------------1--------------1-2-----1---------------------------------------------------------------------------------------------11--------------1--------------------------------------------------------------------------------------------------------------------------------1--------------------------1------------------------------------------------------------------1-1111----------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------1---------------------------------------------------------------------------------------------------- 5212FJI-B4-1A8E64863644534334363746586365562445455A8AB876737643334332557222221343223637599894CB79477256DEN1i63p*******yvl*****v*****H***rt***p**xd**up*km******P**icWqP*bfzh*gQ3353C321137CE*5*B3378BC3 * g.49 Cysteine-rich domain
[ 203] 112-2322222222222234433122211122--2112111111121132111121233311112--1 2573834466633444433-333345333332566646553525435343334553332254446377A98222234333B5333323435423332-23566695563233333322222222633334433446888A22263A48888746444334334734A9A62322222422224441133335555555555555555535443455544464432222224622222222222222222222334244233334433443233334433333333433444444444443444333333333544332444334444333334435344333333834216661255211543311122235527633544444549895555555555555555556-77667666975496668887786657555677666667622222222444225545555555544555555555555555545546666257766999898555556666787657A6767674499856666A6768665765657533333335555564843567455565444434434845545953644444333333343333333343345555667775559988888888888A88A8875-6555644244456575556668698676-66687787876886666685555555765656666666766565666776654577767777666445633333575575755444565444445555333333333356AAAAA9788666657775444454445555655555767757877777666555544535565664444444474522222-222232222222223322244455454441744 6522DBA-H641688556555545445546555555555545555545475665457555654442222421444222222555455558D65748656432698G-9GFSPbGGSCBBA9BFAUW8VE**G-TIWBA99H9DGD9DB78FAAICD9BICFIIHED9TAEHHLGD68D8*6779CRIXU5SEADC98CC * d.43 EF-Ts domain-like
[ 204] 1132214333333335-534222244433333222322322223232234562212112224452-33 5474755677744444555-543347555554445546BC3433657444458886451186B694AA6532455444213373323255482634-1269664754751-1-11-2111111122243332233444342227433633344333363333333565533333333433337553323124599A9AABA89AACCA855555B9944564344333358544444444444444444434122344323225633542425322222232122433222112211312222332232222333432333353186555544432332556332344335422344533156345553342634555644335559543335634466676665656-66756A46IB44B9999B9CBBA98C55456865595664444444465553345222333332211111111121222142243356434443697777A66666667A9AB9987BB5B7A247663575586D76945332336356444444336448365534626655634334356555545885A44A5355664534434333333233346664444568477877476644677756893-3334322122284876666565654576-66869576566565565566978777755555565555555557665665543766666666666223634332766644846444544444444444778884636693BBBBABAA58A775A98444343434365575555556767665766665533332242663333-11111116-1----1---1-1-----1111-1---53343453334527 2244AA5-D464ED94DB8FBGBHHFD9777767989DACA986669A889BBH99888697349555456494565557664867667AM8DA9E65545DA9BB-6FCSGJBBGK9CF8889DA9J7Z*H2KFS85DCF6BED496A8CC6F9IB8FCE7AKDEDD8ADCIE954ED*C6EE9XGJQ8HBA5DDBBQ * a.127 L-aspartase-like
[ 205] 1111121111111112111311311----1--11112111111----2---2-11113132---11-- ---1---3-----14--11-11--1-1-111111-1---111----------------------11-1----1111---11------1121---------2---1-1-1--------1-----11---11---------2---1-11211111111121111--1131111111111111211--111-----11111-21-342313--22111211--2---311112-1122222212211222122--1---------1-----------------------11-----------------------------------1-11-------2-111111---422----2-11112--1--------2-12----11-1--1----11---1------------1-1-1-12-1-1-1---1---21--1-----2--1----11-------------11---------------111----1------4--11---12121-----211111113121111-1-112--1--1--2-12-1---1-1-2-11---------1-1-31-1-11-2-2-1--21-21--211----11-1-1--1--------1213111-------4421211121-131112-2---31-1221----2-14------34232322222222222-23223232222232222224542232132323333333333232222222221223343333345--3------12121121-111221123221221----------2111112123212121111-----1---1222222222221121-2-1-----------1-11------------1-1---1-----------1--------------41323---- C878PKG-nMJEKQMFGLFCFJGFGGEHGGABBJCGCD9CAAFEHEBBBFDEQHABHMFGEFHEDFGF9AEHB9DCDADGCDDDAE9B87HBGCKO799EBHEOIK3FML***w***cRZWVqg**Z*c***5*w*RgdW*df*kUkcWNsNM*Z*ZhpIQUNZQQFsQWZVcOMCGQ9*87A97fWZkKaSDFKKOVC * a.47 STAT-like
[ 206] -------------------------------------------------------------------- ---------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------ 488C114-5--------------------------------------------------------------------------------------------------2--**********y*****x*z***K***s*w**y***b*xrd*wd*y**********LIeHP*d**A---311311-------2------- * g.60 TSP-1 type 1 repeat
[ 207] 335124988889AA9A24535334533445731121111111123-2111343123224435341--- 55A8D344445322C6788-AC11ED888885BCEC8FSV67587755676297F5743354P57BJEC9512224331--28121114442-2111222218474432-------1-1----22313321222244423---393645463133322112324245484212221212222555442211545555564536565457844575552625587644444473333333333333335967573718713322CD5467568872666644644455433343233333444444444444456633366674671577776677552933112283-2231121631A443725444314421784553333378FCE867797C866676566657-DCEBCDEH8G63A77ABALB99FJ5D876B87787799B444444448555466522211-1122112222222222212222215477-A986A9DD9CD88888CCCGA9994888RAGFB23786566779695C5375311133322223256465346C48444455333143636635433435416111-------------------21377755A95347551132115331222111223--1663511111143328338887877787-88887777788787868865432344344444544443644456433445731455555555555112311111334346696222212111122222655664658634678875776769857655454453443333844444534446456756323222222345533221111111131422323-3-62222334352233---24345313337711 881164C-F56166365965656777576465545324234436864747699C4446565522223214342323323524443233448452345534335747-8G9PCLDDIJCB8AAEBPTBP9c*H-JDY9AB7J9AJA8AD99L99RCICCG8GhAJF9HJFJJCAFC6FB5*46579FGNK7MF9D9C76B * d.87 CO dehydrogenase flavoprotein C-domain-like
[ 208] --------111-111-11121--11--2---2-----------------11--1-----1---1---- 22112------------11-1-----11111------11-----------11----1----1-1--1-----------------2---33---------1121221212--------------1----1---1--2111------423222421--1----11-112222------------------1----------1------1-----------------------------------------1--1---------------------------------1-------------1-11111-1---------------1------1-11----------1-----1----1111--1--1---------24225-----133222222222211111222223-112114-2121-22232222222111222211111122111111111-1233-111111111111--111111111111211-1-31131-------------1------211111-11--1-----1121312112221212222---------11-122-2123--1-11----112---12---1-1-1-1----------------1--1------2413452232132112554333-5-53-44--13124-------1-1--------------------------------------21---------------------------1--------------211-11222223322---------------------1---3767764453644447444---1-11--254533333344433-2--------------2-2211----------4------------------1------------------31-2 DF87FB4-I223**CLQPGMAAAIGFC77A879BBA8787787656caITOPOSJJQTIKPNfKBB666DE6HBAMA6FDCGGERI955**kQLXkCBBMG*DSf*-6I5JOLMB9ODCGJSKEUOAaFu*T3TFb7DECYFG*UCEBH9VB7*FOGGQBG8YGHsQE126bSFC48b4a7645D****L*mAC****7 * b.50 Acid proteases
[ 209] -----------111-121-----1111112112232--433323321121211-11111111--1-24 22B2642433332344434-33333633333336665798343234221452654234--4332445454311111114231---1--2222-511---2334412223--------------1111112112323332211131522533233334333333325224533343333343344411---312555555554555555532222556234442233333346244444444444444443545411331232346114421223244422233333232222222222223333333333332442223333-41153333333433242212222112132141111111-111211-132514766522222355353335553522222222222-55355454224-8447554774225544333433333434244444422222432--------11-------------------3346323322334455344444444544443345435432233422322442445223332332223333354323312322132212222222212222233235424211112222211111111112421211224435635535444433444444444446--21112------34582353333333233-3333333333333333333344653333333333333333333433333332-324233323333---3-----222223223111213122221222445442321235555534465444437861---1111-44444333334443322322222221111211322333311111111112-----------------1------------11111-421 BC77CDG-iHP3EEGCCDCBCCCDDEBBCAA9A9A89BAABAABBABAACBCCCBCBAACABCAC8796779B7AAA79A977878A99FOECEEDDEECCE9EEH2B*LlPOLKQPFEOIHIFYbH*I**i1UVzPGFGNEIPIEJEHKMIISELHGLKSTIFIHJMDIVJMIF7UTT*NOOLKeNctDXOSUOKLKl * b.62 Cyclophilin-like
[ 210] --1---1---------2-1-1--1322--1322132-11--1-4613542436----1-11111---- 2112--2322431-13344-462292444444B4654645-24414112112234-23--3223214123232221222-2-2111123332-311---2221212131-111111--------211233122-212233---342B645652222------4613C631------------11133112311333333632323432211111333121311364444432-22121111122211--11-75315611527331163211331445222111122211111111111111111111111121122211123-235444447455528665352823113--133431323--133632111225221-----333272-53343111111111113-34224635334-2111313314255723-2-254341--2222222231--1221-------------------------------31--3111-2332221333322234444244233535-13432233344242152521214412-----11332421321-22231224-22242532324412552---1-1-11---211---1-1-11167344-21-11-212---1111--2-1--11----2427------31222423333333333-333333332333233333246422111333233333323332333322223--433333333333---1-----22316-51------1---------2222223-1242333434332233222321121-11-12---1---1-11---1111211111------1222--22----------344231-2121111111-42111221112---2---2-32 68A9JJC-XCB5MMNEGHDFIGFJLHKCCBBBBFIJCFEFDDDEDDIDIKJLPRGFIJHFGGBBCCCB1CC7DBDCF3EFBDDCBECCD9IFGEDHCCBBAGFWTS3IGVNcjTodaLRPJQQTtgMsR**iC*X*KNTLYRQkPARQLKfLP*UcNRbDU*PCCJCnFJtLbGA9GBD*977AASOTyFZPCDUgYaE * d.220 Metal cation-transporting ATPase, ATP-binding domain N
[ 211] --1-11-----------------1----1----11----1----------------------1----- 1-1-----------------------------------------------------------------------------------12-------1-11-----1--11-----------------------------------------------------1-----------------------------11111111111111111---11111-----1-1111-11-1--------------1-------1--1-1----1111111111----------1--11111111111-------------1------------1-------------221----------1---------------------1---------------1------------------1111-1---------------------1--------------------------1------------------------------------------------------------------1------1-----------1--------------------1---1-----111--111-11--------1--------------1--------------------11--------------1----1-----------------1-------------------------------------------------------------------1------------1--------------------------------111111---------------------------------------------------1--111------------21----------1-------1---1---------------1--1-1-1--1- 1112573-----1--2-112---1121-----1-------1---11----1---11--1111---1------1----1------1-1--1-1--1-11-1--1--2-924*********y******v*****5***s********l***o*zk******Y**UmbTGiLHcMMYW-411A----1333615-13-122- * g.17 Cystine-knot cytokines
[ 212] 111---53655567513-2-22131---222113----32133-11131--21-23355331232--- 3562743455634-MGHBB-BO55VEBBABAEJNONLKdP491552112112437437--85F3A5JCF65244421153C531211112423511---36-114265212111121121111295667578426111443333-654434533443221331521316454444545443445622--11151111121111112111433351122322423644554772444344334444443663343133321423-144212242324541112-11-221--11--1-212111222211221-331112331147A89999ADB8C943BB24449231116354E995A3171A4452411324A9A91121138E9823386559444444554471337247444AB-6877657445BA223B4445324343488888888444354313312311122--11--311111111221134ED2235842868B999544666A6466614G8E4B46134286B83253443522423243311223222116211BD5654534A764-4552625733454583711-2-31122-------1-1332-311334323724432433424432233264576--12343------21313344335434432-33437353343444344421332-21-1-1213122112222153433333--211221122122--1222232222138-22111312---1--1--884683532223763626575633255363111222112557444444546443155645223----2262661-33111-11-1214--------11-2----16-------233133-3313511 3211966-934155AXRVJTEKKoNlc9B9AABA99EGFCDEDEBAFLGNOh*sKIJGNAADE7B3871642D7A511339987B5855HWGR9GAEDE995CG4A-3d7tEFCAFJBCBCBJFZMDS9W*H1KFFAC7ALAAIDCA797F99NC96EGEJS9J986A8BHGDGD5B82z45587CDDMKMD788659A * c.4 Nucleotide-binding domain
[ 213] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGEIHGG-*OJ7EAPA9C9DBDFEAACDDCEEFC996A9A7ABDEFFEEFGBGD6CGBACBECECA7C48BA9A8AB7BB89A7A7AABHIK9LLSKGLF84EKTO6PlBl******nccdjxi**Y*e***G***ShVT*Vp*oSooWVtRM*jvtxxGPJUaYLGiKLcW*UD7LQF*JJHYJ****C*pIHVWZZF * g.66 CCCH zinc finger
[ 214] 44344566766787673567676A72272355546549565566745675555843333334434156 46B5731344323359A55-56555955555586566495344636243313457366--558366B55332222222117744312122322368---4544463323---------------43333434352433771118623543332411211212344475431211111111112324411235355556355465434422553446444623122222223313333333334433322232122222211225511431121223111112---11-----1-----111-1111111111111111111-16449CCCBBAD5A5384453323616231333E93694126432411413463445111116688822345755333233333321445448587631922444C656546743332333334436666666635633554-----111----1111-11111111----4367335652676787856665778C6667569BF5FA72456685466674465346-1133322222222125864CD352-4852111-B7B4D56446676695B-1--1111112221111111--22121542344734224334334555744574484--11331------64534535555566644-4555555555455555554556563547776677776768667544354542-433333333333---23333333333457711134213233121233343343358376766755454475877----------43345455444344333232233311111-233333431-------5-2-1----1--11--111----1----243222422235-4 6544BA8-H679A78EFB8EDEBEGEIBCCCCCBCDCCCBCBBAEDDEEDDIFOFEFCBDDDB8798B59AB9ACCB9ABABBCBB577AIAFECB78889A89892BXNWXTNQGNCDDDDFEaNBSCs*N-THZCDFDICFKCAFDDDHC7WFFFFKCGLAOEECEB7FCALB7898j554A6I8GGDB9DIC9B96 * c.31 DHS-like NAD/FAD-binding domain
[ 215] 33333344444444443243422344445444333322322334322222222344444423333244 44649337666534657DD-D677D9CDDCD77888A9BA489955454452644333229665578755433332222334421-1-432222222--3225433222111111112222221233423233534335422263245344222223433331113432223332223332265465222546777778779778886768866887668664554545555599999989A9999A88676615355361115555555455623336664665755555556555555555555555555655444555435453222222222323332444224236234455434233434453411334444332333446675445554633333333334-55656755434384585557653356424446556735643444444333234442313322322122333323332332425244332276558888A978888888898889789998A8722778455446545673364436542344444574354325232321222222211112131333343331111122222122221212212221236564556446555555443544554445562-243551-111145784555556656555-55655565655466656663437644544444444444444444555445541423233323333321544444444455445222213244433332556554544746776756577666547764222233224433555555667663343333334333311222222222221212111321--1-1---21-111--1-1-1111-11-111214312 66335442K654655555456656557554466556466656677754476688466555247476775466565885988443453445755364455634362544C6HHEbQ*U89FICVA*wGq5**E1Udp99ELe8D*J6ESaDw6AW7HDCT6535D6A48A8347643794Q546569BHB5B85738635 * d.74 DCoH-like
[ 216] 33223454555555554222222242224343222222222222232233333255554555546123 6564844444444643444-44444444444444444444454454444544645444444554444655444554444444544444766646554-1444445445644444444444444544444444444555444447566444455444444444443585444444444444445555576544488888688888888766665588745484554444445644444444444444354454443444444444444444444444445544344444444444544444444444444444444444444456667555555565666555666855555665455574665545576654544444444444544554444544455555555555-4444545445445555555555554454555455554554444444444454455444444444444443444544444444444444534444555555555666555566665475666664466644555544455446444464444444444443444544454446665444444444466665544444444444445444544444444444555555565545555555555555655555414455544344465665545554555555-54555555555555555555765555544444444444444445555444443644444444444335544444676644755444444444444444444344444445655546565555445455444444444855666666676664444444444444444444444444444444555554444-444444344444434444466666766664544 6634875-H5667695597566676566698778775545565655768898B9786867677554545564555662665555556556C55678666856599B27M9ICOC9CEA998AAAGH8JAi*D1JEQ9AAAF89DA8A9C9BABGDGE986CG7A7B7A7A76A7A7898*9A877D9FBBDFA9A997D * d.67 RRF/tRNA synthetase additional domain-like
[ 217] 22222334333333332333443245545262322322343324434332434445443452323132 3583944555545369944-47336A44444687775676442443544445867439226553748898322222222243524222656516332--2534353533222222222222224332232223334554422254355444334223232223425445522222222232254333333334777777774777777654454778456574433333396333333333333333333334344344333333334423234344422332333333333333333333333333333333333333333243266667687464473355553232243433A945233344333233272322242222222543332324324455455455A-333332448G32AAA6668897874233339A55556772222222232232232222222332222222222222222222225335423333377788854444885976775688A25342233223222433346242232263222222222232345435464235333354634354465657343221222222222222222222222222334635667455333354664436365357112322211111153543844444444444-44444444444454444446643344534333333333333335444333332656566545666111422222333322785333222222213222544463322222556557544877625442222222223222222222333224555555444333322243322332222222222212222-222222222222222222224322252222322 7666AAB-hA96AAEDDCBEEEADGCEEEBCBDBBACCABADDECCBCBCEDFIABBBC9899AB8787A87AAA887899AAAAB799CJBDADECACABF8GFI4APIbHFGGFGA9ACABBIG9N9Q*A1EDKAB9BG9AGCBAAB9C76PCABADALMDCAGBGFGNCFIEABFB*B9C9AYFLUCKN8BHDHED * d.127 Creatinase/aminopeptidase
[ 218] 44114-21-1--------1212--111-12-1--111--11--11-----311-----1-12-1---2 3332422233323343422-223332222223232323322232224222222232332234322233444222223333323222323333221232235243423233444544222334431143322225233334223334342456112222247322333254233222232222321343322331323322323432623233363342643245222233332323333233333243543432322234222335533232232454122234322433333333333222232222222233222322235345222234324353434342333323223323334223434223532223243322224323644634553343333333423213222232233423332235632742433323222224424444444422222242224332222224222223222232212243223225333254433412222223222223255422332334423322331122222223222332222233373236653223354446354564456643347744324534344322333343243522321443354345244443443255433235334122622212222243354223544434434-44346444444443434443233354434332332222333332434342342334444434444223312122656722453444343321222333333534522424564535523323422322232222225224224434343551243334232234322333333443332322222323321-161-12111111211111133233343523543 55129B8-LE97B9E89DD6B88765BAA89A7C784867966CAEB7CB88EG89BA989867986542897C5698576A98456469B69E6447571G989F2AHLUgaWhrSEJMLGPLufEpH**n8*g*KLKFYJKTWGPDEKbCD*JUOUQCLTBDJ9BXFNJCLD97GA7d86667*EEI7SU8A9DCA8 * e.38 Release factor
[ 219] 33342554344444433545433367745554223232222223123234544223243324333155 6573E55566554426577-7622C3777775666685434BA934436675543764336533A7LIGJ43222333123262223222222322111253338345311111111212222233434333444655771129496755643333433444554678863444434534333333311486522222222222222322444522254456433333334833332333343333332233312144142-36623332213353333222112111111112111112222222222232133111222232322-11111211132433112214223323386353533242122122636533453333677986557787833333333333-77A877774744444356744333363349446655745555555555555657933322223223322223222222223333444234444465666755677666756999255565555233334444565545444444447465554444546444323333433344323222232223344A92433322222222232222222322234433332323424222222222222222232211354752--11124332232222232222-222223223222222222222222242222222223223232222222222222222222222222223332323344322222322332323222332222222334522222223222222423323333333322224222224222322333333332222226222333311121121122----------2-----------11-21211212224343 4723HN6-L95488BEEDLKGSKUVVP88ECAADHBCA7A7CA985GFGIPKEIBCPJFECC97A8974B8487667588665679756BmNEGIb87B79HAABB35KCLEFECCE86858899DASA**F4MHX88A8F98D99B6A6974C79DG868D8C8HDA98v469A99AA*899D9Orl*C**CDB768B * a.128 Terpenoid synthases
[ 220] -------------------------------------------------------------------- 434-8--111----4--22-21--15333331--1-1733234472222553AB75CA--1182716886111116311---223856775729661--7JG894FC563333333444444442123342222544474--195112-223331133343112-12241263222261233ABD4411-GAP8888868A8888A888DPPET88ADJIJD29DBBBBC9IC899999799999998777AL1636529111BCCC658D756888A2321111423222222222221111111111111333133333-6LI718A8998837353889222E8H--D54BAFIPBF3Z839CCC6-1-4514552-1111223432111212122222222224-11212212442-466333633355-12-12221311238--------1--1-423------------1-21-1----1-------213-157777A9989877AA78876BBBB699976676-1778445556434644594757A5456666666255348864A533O43333ACB8ED97C6546JFCB122211111111111111111222488CC68877679D99AAAB8688998877977--2D88A---1-1676966989A7877767-9788A8878798888888777C7733777778887888575789758776741877777767878--375645486776985A333636322123224BBCBBDBBBB48989A57659555578781111111114DDGECABCBGA9CB665646645513233-1A55334488898899C6--------------------------22333222224945 ----754-623-26A985BZFNEFJCM542222YgDD74736621159GaAMPMFEBM9F89--1-----------------1--1---B7987433323--38OB-2624685846435136496382FY5-8594125614A6352156248265672-334161I3335I431GM4A755Z4ZJCh6KS-254553 * d.7 LysM domain
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c.73 Carbamate kinase-like
[ 222] 33131354557654655177754871135355325544644455558A52775443235651221--- 38A39213332--168766-6C--7A6666639BCB669B543643323---5561-3--438354A6D73----1---8cV5578572223-3-2-121421352834--------------331363713343AAA75433763633223111111121111143223-------1----542552213-73333334323335333366263323441--211111133222222222211222311211--11--1---11-111---1-------12-1-1-------------1-11-1-------1---------46714222212212115222443121-4F-244*u459B-AAB111521-44553341111348E8A83C9F7D84445444343A-A9C9AB9G9711788867669877C942374B7A7874844444444955-5E341111111111111111111112112111122553-48749C9A9ABA8BBBDD9DCCCD6ABADCFFA259A879677B689799765765592221221312FDA3IJD77ADAEA99E1EFCFC7C49EDBA7CBN9DF66769A383643323348J89844A726467-5-4B8DDB4ENDGHBGFIECOD1--4A53111111KCC9DG4HJJHHGDKII-GHHMHFGIHIJIHEIHGHDDDDAA53EHGJDGIKHIHHHLIFGFDBBFCCD2-A8899AA9A9AA111311111111184672BABCA94646456684444423344438889978466A89B8861111111113798E34444BC8795544646343111132A2554466--------1-1-------------------------12212121-15732 ---11-3-7533332565425A2756244443333222333325331252996546863566322141131-53211-11132234--1365634B2323352638-441C344734322124233262BQ2-8323321441362224121475781B2846A83382211A511122N233-2B37J282253444- * c.81 Formate dehydrogenase/DMSO reductase, domains 1-3
[ 223] -----1--------------1---11112111211-------111111-1111-1---211-----11 121-211111111121111-12--1211111122221111111121111112111111--11121111111-111111-1111-----111--111---1222231221--------------133233322322---1111--15345332112222222241132121121111121111111--1-11-21111111111111111111111111--112111111113111111-11111111111111111111111111111111111111111122222--2222222222222222222222222112211111-11211111111-1--111-111---111--1-221-----------1211-37449-----45H784335643522222122227-443342428F6-9556IJIGNGJF3329528685774951111111134411112----1111---1-----------------24788-145565556572544455645556366534344111223313351536235431-153111111112422222211123111111111111112123637A111111111111-1111111111-11233434157624345533385555437346366-213311------22111311111111111-111111111111111111121213111333333333332322321-111111-111111111111--2411111335322A6411112-111112--177657722532356655643454634224322222222143343333357745666555623211111-12221122--------111------1-11-2111111-11----1--1------1221 3211872-6342334GGH9IGEDEF9FBA9DBBFCBC9A969A7789AGRBFPG9DABC9BB3343233443345332332333334545E3GACA5764486526-4I6H8878CEYTSdQKO*xV*d***8***jYWclWo*gaaUHGwSU*IT6595538B641934658542543J2344685AE8EB65A334D * b.88 Mss4-like
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aHPQI79B58B6HA8FAf*K1FBI9B99K9DM87D798E97FCGBBDHUVBFCBBIBCJDHO54766*44659MBHS5FC789897C * d.128 Glutamine synthetase/guanido kinase
[ 225] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ C99AFCJ1cHT765445525555473531333355426364663434467536556656466666666356565467677666656455333546774652259A35CR3*******xhrox****o*s***K***Zxrf*o**rU*vgd*XR*w**v*g**VkdLAqMQ*SWOVX98B*9A978KPVa6OC74BJILA * g.16 Trefoil/Plexin domain-like
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nC1ABF977BD69E77AC9CCA9CBA8AD897AE956C56O89D84687o36575D88F39D6498456 * d.131 DNA clamp
[ 227] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------11-----------1------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------- 1133DJF-gLD1O9Z12PJFCKKA2ECGI8AAFABC9IELCHGOBVi*12HE2FEBE*5G35E8C7992F89A76AD798888E92E8DT*i2OGdHDI*D*EXp*2GR2XVePP*QIJGFLVVsXIcD**X6XVfKILHYHM*OKMKGIVCLjMTKv*FQP*****G9NSDQKD22MEpA7FD8****S*R35d***6 * g.40 Retrovirus zinc finger-like domains
[ 228] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------1--------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------1--------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1----------1--------------------------------------------------------------1 543346D-723399C9899A7A658378878876766656475687887CB99C77AABAAA83678644A8455695887545449A9NcM8RVKABA78IAQOQ2DULn*****thYs*e*i**b*d***4***Xmm**dl*uRngbPvVR*momlsQXN*WVgSpOZVLTYK-9CI*DD97CDJMZCQAcWECDAF * a.21 HMG-box
[ 229] -------------------------------------------------------------------- 211-1-------------------1-----------1-11---111111---111--1-----------11-----------1---1-------------------1------------------------------------21---------------------------------------------2-----------------------------------------1---------------------------------------------------------------------------------------------------------------------1----------------------------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------1--------------------------4-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------- 5546*k--J762324-1513111221234211121--------22124311212111232221-11111211-32------111--11-33-1524-----41121133C*******kokenwm**g*x***6***Vlih*kk*yQpjpiyYb*gdX**BBGXPg86KAIH8O*61--11-1-13HEGF3B7-134455 * g.43 B-box zinc-binding domain
[ 230] ---11--11-----------1---2--11--1-----1------1-121-44------2-1-----12 1-4-81111121--111----2--1------F----3-21-C6A--------2-1-----41-113389751----1----112-11-2311-1116--12-2---4--12222223121111-43-1-1--8224223-1119-723244511--3--1----26233C-1211--2-11--1---------22222211211222213441121411111--111112631--1-1----------11--2--21121--------------1---1---11-1------------1----1--------1----------2112--------1---22111---1-31--1-111--1--2111-2---2-11---11---1141411213--11121112-12--11---41--------1-1---11111--1-2--1----3-------------3--2212111111-11----1-11-11-2121---21-133212222221222274133334112121421131-21-2111--23---32223221111111-14122-62-11-3-23112-1-11-11-1121124----1111---12112123212-212-111-1112--1-11----22-222-12---22---2123------11--2311111111111-11133111-1121111112222-122311222322322111211--1---2--1-------------1111---1121-1121---1---------1-222231222222441311122111111111--------2--------------1121312121------7-----221----------11-----------------------1-11121112111- 13--MMK-J765654B6ACLAEAJEQJCBCC98A866757699A75BGBXKCGQ649P4A5A5333431252637151413342425443886A8*2424465667-2*7*nywusicebUhlZ**X*h***8*w*UZZVldi*qIfZLN*MQuZobidDPXbcUO7aGEVFTe*3CO8u75524KCEJJ9E96BNAEF * f.1 Toxins' membrane translocation domains
[ 231] 112-1-222222232121111-1-93323174333-13122123314324666-11---112212--- 21122237556554555BB-BF22G4BBBBBAD89A455622452446611143B234--43614142753465545511314-2122-11211-1--1-2232212321111111-1111111211131121-122273--136-4353322-111111-112214121---111--11---32221-12445555547535565554244445583322233633335233111212123111232431296636551235772245522312678-------21121222221112---------1---211222222213416555658655535773112422444232-3362-32212523323412-6225-----463365145332322222221224-37414A54746-2112326731457A-417155444113--------311-14341---1---11---1-----------1111-2411-12112655455344446634544425555466723894544885524524264434212133333-2224411412122142334-22112213-455425512131122222131232322313-1346244112313241433212322233322342---2216------65552313456355354-53344453365463333345782322244445444454544443454332531423223233432--21-----2233612--11112112222112111111113325455672755421323434---------32223222222312221------------113344--21----------334441--112-1------2-11111113-1111113542 9877HFB-VCBCDDD8CDCAEDCGDFFEEADCDGDEBCACEADCECCD9DAFIKDCC97CBC9689951872B89763578AA9AA4645KAC86F675D787TWP2GIIKJSOOHcPFFHFGMVZIVAz*P2aLoBHDKFGEHEBJBAENGBdEQGCL7IjMB8D5aFFgNTEB6FD9*C98CFBGKYEJUA7GJFIE * a.23 Open three-helical up-and-down bundle
[ 232] -----------------1------21111111432--------11----13123-------1111--- 6666555555555555444-45667444444656565566555675575555555655555556555567555555555555555555666656664--6797677967444444444444447776667666666666722287676678756555455556667776655555555655596466565955557575775576556655565756555A6665555556566666666666666676666555655675656666556557656565556555666666666666666666666666666666666666559967666666666765665776577557567577755668566676656552555655555555556555566655555555555-65555556555575555856665665567556565555555555555555556545511111122565555555555555545556656598788666666666666666666656666888867886787779777977776666676676666797667666665555455555555554566666677564555466566555555555555555666666668667667777666666666766665-5666625-54566666666666666666-666666666666666666667666666666566666666665666666666656666666666665556555556777666756666666665566666666667666666666666666666666688887888866666666666666666556555556666556666666644454444551--2-1---1--------1-------58555555456769 -1---22-422-22224222543434433533332234244432334422332434332322322232222322233-3322222222212343232222243223-2--353322242123111-22-BN4-23411-222241311111--13123325122111324-33322144B43322C36828A3242321 * c.59 MurD-like peptide ligases, peptide-binding domain
[ 233] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1----------------------------------------11-----1------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------1------------------------------------1-------------------*******vekbp*w**f*t***4***ephe*k**vW*gXb*XW*b****QjT6FXMFZONWA8D4---------------1-------- * g.27 FnI-like domain
[ 234] 5533453464454445456564637557455554444233333443462696A344444443333243 4484775677574487777-7944777777768999A988487656472443666745--678366A978322224442344344544433624225--35333626362222222222222254334433444355533443514B444323322222222232511312222111212316663333243333434444344445454334544433344356444445444445444444444444445545155114436622555232213324443333333333333333433333333333333544333444445733444445533342442222533335443254321423124343422466555433333355444454454444444443445-BA6BA6A75552544685446644445554444D444453333333343343334111121111111211111221111111I13536335554667C766655657767555555755555834668446556965545554534433333333433347365343443434443343535433556578433434343334434334333324243554536644I7635655545565545555466--3233422122255443464444444454-45444454554455545545454435444444444444444444454444431455545545445222434333554435645333443244442224323333324355555566565775664C622222322224546444444657745556555553333115522334511111111123----1-----1-------1-1----33343343333543 6343463-C4443345AA65776764755444468545655555875666A6A677867A794553444345464542543335367444H6A77A555556653425K3G8877CE7AB88CBGD9UBw*P3RFQ7AD7DE9A98A985C46EA87ACA86378B7235119AA557Ai987C7IJDa7QC7892566 * a.96 DNA-glycosylase
[ 235] --------------------1----------------------------------------------- --------------------------------------1---------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1------------------1111----1-11-----------------------------------------------------------------------------1---------------------------------------------------------1--------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122B9O-9447GFHDFEEEFHEEEEDFFFEEFGHFDEEFBFFEEECFGGFGHGDEGFEGGGDDEEDE8CECDCEDD9EDDFDFCFCEEDJDFFEHC9CCCIFQUS1hXI***w***hfebhrh**Y*c***7*y*SmfX*Xk*gZlfbSvfS*hxmhnSdaMYSIGOLMTELeN2554F7684496DCE967A****J * d.189 PX domain
[ 236] 33312244444444443233333384546354323344434342222212222333322223334222 4672731222233343322-2433422222234333437744433354333278653433447348B755411111111213C32223333313221112423333343111111111111112222222332245554411147333333333332222222333333322222222223233233333222222222222222222222222222222222222222221222222222222222222221111111111111111111111111111111111111111111111111111111111111111111111243234444444242133322333222432212552343344233324133344333433333633422343453334534544461665676645L5-C88797AA9CEE892338C75565GEL2222222242236433222222221122111121111111122229244324454366666676555667966664668656642344663344443445224352545445444434434422422342342223254444554355656523211112212211111111112212233554535845546555545555555556555312343422133355554656776666666-76566666667666666666665556766666666666666666666666652556556756555332433333333343454455444344433334341343433364666667689877746662332233233555545555555555534344333333333313323331111111131211111-111111111111111111122222222224222 67448761NF95A98986888878988776677666666675677797778888867677776775863676658674775767758887B7867856557668DG3AFHhFKGHIF78F98I8CKAO9b*A1ILN6F95j79HC6A986E65JAE9ACCNS8EBDCKDBAGEEA9788*66869LDbP8F989BA79B * b.44 Elongation factor/aminomethyltransferase common domain
[ 237] 44352144434334362222333633311341232222321242344321483144464533443-23 1461112233312132233-332269333334733348B8253422412332344112224423434333434444548234411-2167572543-111221372323222222222122221546543444345556733453679433446663345343245567423432324222233311884657446466555555665C5CA87555386657777777853322222222222222433228241441421233554553143344455533334554445444544423333333333335556515553576BIAAABBBDEBE8DKK8AC87A525788436688B354648678336235422232222335334225A45533333333334-3382272465316776645A6676744342366566544434444445223132422222222111121111211211121111224545388376576874444455444555649447B84335643423364687823332326322222323222223BA5G56759C99818778429D711115733423421112113222122112211222A9D454445355788777B777756577B51111332111111D8BA493AAADAEEDBA-AABABDBABBACB99AAACDGECC668DDBBCCDCCDCBCBAC9987777A3-76666766666611421111133531454954662713322223444545454455555565944886545545111222121365698988988B8A124121145724251136443333-----1--4-3--------1--------12------44745A386A2351 1-22546-8348563797985468A74556433767675655734378589DG97744435222-2241343431431231-11215537C695692324477587-4H3D99957A5736644C9392Ih91DCE5423926834542373384A8473523A61B525B17814564H44562547BBA95546548 * e.22 Dehydroquinate synthase-like
[ 238] -------1--------------------------1----------1----D86--------------- 553172222223225BBAA-AA55D8AAAAABBDED9A9A255844523443455435227693977898322222221111123233444414342--56666324143333333333333363323433335344444---6166666663433333222444498742222222222222212222213133333222222222211113222211112331112112121111111111111-11111231222213331111321111211111111111111111111111111111111111111122111222122123222222222212222222332112421211211111113221-32614244211211322222123322322222322223-334344442631322244344433225245543333556333333332222334211111111112222222222222221111133251222245444453233333563333344555565225553553334666333732333222322222324664C78422312322215554443449998FC27534122222-212111111142122456656955684488888576888888678672-34232------65444534555443444-4444444444545344445565534454433333333333332644444442234444443444411275455555544995922225222222233354665574556699998A89B777758774333333333566877777678AA676767745522221121AA66553332322222311111-111111111111111111112131222222234 64339AA-N754687588766667655777767755776756776866575576666466456965465656566675886666874345A988778667686IHJ3DOBSLQJLMOEBB7DICaOAYD**P2JNa8CB7LEEJH7FDE8HB7RHJIMJIF8DIDBANHDQCIGB98C6j76599MFJQ8ML8BHCDB7 * c.112 Glycerol-3-phosphate (1)-acyltransferase
[ 239] -----------------------------------1---------------1-11-11----1----- KCP---------------------2------1--------------------1-1----------------1---1--1----8578ATSRJ-R88---7M8DDXBR9H--------------58899A8AC9AA2--33-----72375411111111232112547A7131121141121-4144227-2-------1-----21--------11-----12122111421332221-2222312-12-1--------2--1---1---1-------1--121-----------------------1--------------12-7-----5---143334---1332-1--2156222122-2---1-42K6FI7782222296A8D84A7677311111111112-333253341261422543474323396872141121221EEEEEEEE5LKE6B6611112111221112221321111111111268IA9BBA4ESSUVVOJGHJIPOPSMNNLBLSLRGQLW35HIMACBGHTFD8H4FLIAMEICD1122222A7B7AF88I577E444955719F7CBCECFCC9EE76DA6433323323444445444A649BEH6579569686636565366A7784688996--28827------555A3754786566865-7666655567776554556867BE5446765666665556556613866451-634444444444--2922222CFFGG7728222212112113132AAABA9922398JKLLJLKGAJIIIB9EG333333333A5669686678BD88GEDADBA677111131B3CC88881222111121---1-1-----2---11---------1-32-22222AF44 --11245-82541222-3521442-12111323-1231---1311144-1132523131-2-11-122-------11--11---2--2--3--937-128131-AA11-1R8AA5F744556CALM4E6Fm52E9H2561F69C525542F24I6974B59A5B535B57616H5152143-3-1231G24311B5341 * f.5 Outer membrane efflux proteins (OEP)
[ 240] 221222632222223332333332655555541121111111121264325A7111111113323123 21211---------25422-22113322222242331143333221---11212411---112121331-2----1111111511222112311--1---2-1131433--------------13312232332243355111354435225222211111112213264------------3224422-135333333333334323124434332333-1--------1111111111111111-1--12-11122112113311221-1-21------------------------------------------1----1--1222232211221-441----12--614-6223-31223211111--123422C1222243C577963323322222221227-4C5487943821244255A465352211132533332223333333334432322------------1111116131111--11131281111-175535584565754666664523D443---6412422213233131334-11--------11341149541458143556-626546334234244661-1-1---------------21113332211231122321111111111121111211--41131--11122342212222222222-222222222222222222244422--13332333333333323222222222-222222222222112211111224351231---------------------1---5311111111151212121-11111111133221111111111--2222222311111132222222---1-1112-1111----------------------111111111113-1 GE67YUC-aAB3EFI697A988688866666664766756666666777B799M46868967732943434622355455A333437A6HLF9FIJ66664A8E7928yKiPkRWZJKOLONYLhYHcJ**V3dQlIOLJcNQYOIRKKIRKEjLYQNVEIHTwMQSQLYdMTZC5HHI*KNKBHiiw*7*xGCGBDER * b.15 HSP20-like chaperones
[ 241] -------1-------1-1-------------------------------------------------3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------2---------21------------33---3-----------------------------------------------------------------------------------------------------------------1-------------1-2-------------------1------------K---------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --ON-14--------------------------111-------------1-----------------------------1-----------------------------3*v*w**wutpny*w**l*j***5***jzoc*r***g*ylg*hd*g**tnX**od*XY*YR*SX*v-LP--212I1--6-----9ffan- * g.68 Kazal-type serine protease inhibitors
[ 242] 334221434444444532432322-2222124------------311F12422--4-3352345--42 6793Y11122211136555-5533455455534546317365133814-652637525--FE51N6AGBH1-----11-12132-1--1232-2-----1622483654---------------1--1---11714778A-11F3375333811---111-232-79879----1--4----N8A24--132666666967495597859AA776873335854557675952--1111111---11--1---121231---11---22----1--1-33352233--222211132313333333343333144--212123415B1212412B1737223675D32-1633421-2314441432325362-42111-----3233312233233------------322-13-232--122321263132442114-41211112111111111---2--1------------------------------1322-2211-9666796766533269888285524334--446414--1311-21232---4--11111123431-G14------111---1321535--1232AE-51--2-112----------------1--21-3237244-E5686A43CAB2C85623C--32111-------2-11-1--------1-------1---1----------1-32132-----1--1-------3-------1-3-------------2D-1---11112-511111-1-3----112-2322211---21234243513333314331--------1-112111113311156ECHCBBCE3333--1-11---------------------3-11-6-113-2--111133-22111--1-2-5 4213LKC-923246CKMJF7BC9CE9AAA9ABCHLKOKJKLMM9A9GDPoWVbYPLWQDACDG44334245455634264555555445EfKME7D33334L6OVS2BbUvLFEIGFC898AEJJJ8KBV*J1NJV7B9AF9BC77A898D96ICKBCE6CFIOB9BH88S9CJ8-FW6W232NGNxk*Gx*H7DICEN * c.41 Subtilisin-like
[ 243] 11-2-22322222222-22222224222112122222222223222222343222223322112--22 35D4732222223344433-322254333334322269BA5897535222226774232245A262576424---3443455653454446425441--4766A969452222222122222246755565756577744444638A89775566665666664557756667666666666355343336334444444434444345544363433435332333333462333334344333442333341-4443313266333422151345533343234443333333333333333333333333454434443232B84444444-4-56334442324134513455444523324433233537644711111556677587646655665565664157B67D5A564233335447334478444527242344544444444355447552233322233--2333223222222--11225434332344556647B8A96657BABA3767748772566B66456566465647833365353444342577545445333235443111131213155558D34433444333335245444444335523876698A4665788986A988878A797863-3664621----74555655555555555-5555555555555555555668664644444444444444444755555554245555555545522363333355556568844455445545333433333335468777777886765769977222222222444465555574644444444433344444331333333--------211-------------------------32134535342634 21--674-D541665757736547667675555677755525554577767866667567575554563633555341446665667978F7584B8777668677-976KACAE9BE8C658CBAAACOkE1AAA79B7946C3477B5789AC6CB666439573A79E24D56773c34346789C5C965AB794 * d.96 T-fold
[ 244] -------------------------------------------------------------------- --------------------------------------21----------------------1-------------------------------------111111-----------------------------11111-----------------1------------------------111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------1111111111111111111111111111--111-111111111-111----21--------------------1--1----------------------------------------------------1--------------------------------------------------------------------1------------------------------------------------------------------11---------------------------1-----1------------111111111----1------------------------------------------------------------------------------------ 5211BBJ-G74-43821222222122223223212212222222222123212233222222312222-111-22111111222-1-1123313323233222862-PB6z******uqqhswr**k*p***G***funn*j**sguosY*ie*r*z*wVl*iaVeT*MUiVmbN1547J46565C76B2B72376774 * a.11 Acyl-CoA binding protein-like
[ 245] 1121311111111111332112145333344321544334334234341244323334433212--21 12-14------1---1111-11--111111111111111212221122-121---1--1132-1112---11222223-1223131331342-211-112--124-232-111111-111111--11-1-1113212223---3-345245343321223134432669411121211121211122331--1221111-2---111--3112111-222211344445515-FFDDBF5FFFFFGF21-122111221111-211133-----131122253332112222222222211221222222141221112221-1121-----1-211141122332211412321--211131-411113-11-2-11426337--11112-1---211111111113---1--2-13--1322634351144111--31--1--11-11111111-----1--22-1------1--1-1-------------1-122-12--21122214-11111321-11---24---1--21-51111-1112111-2312-111211111222-1-21-1-2--13----------1--213122-----11112111-1-1-111-1--212111--12-3-------11-2----1-11-1-1--2111---11133121-21--111122---2111-2111-223213311-11--12-----1---1-------2-14311--211231111111--2-211-12221-32--111--2--1111-1111211-111--333231--1------3-1----------121111-11-12-2--2-2--1--1------43311111111111-2411-1----211------121311--1333213223322-- 7777IKB1T8BA89CACA9EBAA9E9D9A9989BAB9979899999CDADEDCD9BEBDCDBDB7D99679A98ADD5DD999889A784B7CD8BA8C6888FEI-DJMgWmdokgRKNJUXRorKrO**u8mk*HLRMYRTZRGRMOIrHH*OVMQVGPiGPPOIkCFmGOIF8AD6*477A8dMObFNMAAEBGF7 * a.8 immunoglobulin/albumin-binding domain-like
[ 246] 22663267777777785645674666654756787A99BAAB97767866777B66677475554-44 5783675444444455544-45446844444476664565486774554655445534334544465545422222223445565554445535552--4544564454---------------555555455564554466648A675555556665755576445656555555655565333445424354444443334343344444543433333433333333452333333333333333333343-33334-3-3333333334333332222222222222222222222222222222222234222333365545666466645463334444645334455744A55353774465734565444533333586574455654533333333334-54546556334343343334343476555444454434466666666555454455554444444-1-------------333344545555445655555555545578555545578558745464674355757655586644454444444556666576576576666665676667656667555567556566665716111111176656656755546454666666566776666666754-246451--11166556746666666666-66676666676664666666675466676777677787777786666666644755555555555--544444455555565466767635545645644444444446465565554555565645433333333755464444445444665444444444444464554444--------4---------------------------31333333365653 1121555-613-56443435444455333333344344343663436434434463356334333333134334333-43443333343483363833433333771552L66575A665678587994Gl6259H362585661456467337586965AA6B546E68C67665455Z6437464784685995644 * d.139 PurM C-terminal domain-like
[ 247] --111-2---------211-121411121231227576455755322586GAA511-1-3111-2-1- -2314123---11121111-121114111112236322331423321-11113341111153323353243222233322222112-14444-411---23433333-4-------1-1111127A5666755985773422341556455534223233323424547613421223124114-1111--114444545444544436233214461-16213222223512222222222222212112121212213--1232236232121122433222312211121222111212222222222233211122241D46A6657777564654455465442231225CB961113642232-2-22243221121144X78217DACCA22222222226-44344255B5214555868A6556631228547367522111111112-111347--1-------311111111111111-----121-3S****85554832222333533443255G****7J545G8rik*e*6**7C221113144434444111321A95735365356429787345873233532533321----1-1111111-1-21-133334132162113765622233362444634--21151------41311312222232332-2222332242232332334322321132323222222322232322222322-322442234443--21111112222223572223121---111132322221322535435433453333433311111111114555121123324411412111121212--6-221133--------1-----------------------1---2113124112-112 1-23524-841225144642432351312413222424344336131245436412343456134333423231-13-4342223211221445257132126234-268958389E52543489D47BFh9-87F445364385-555453355861N45548645326B52733CD8*77748847Y364885A568 * e.26 Prismane protein-like
[ 248] 55342244555555642344335673442242122121111111213251222333334342116211 14423312221-3112211-14111612121158884545223323332222654444--433-24664341---1----1-622122--1113111--2346573124--------------1-1--11----1555661113554532254422423323431443442211111211115334444245455555356565544556553455465662331-----6344443433334443321125-2-------1-------------------2--22-------------1111111111111111111111-3222-21111311212132-212321--32-2233335313431124-314113221--111223442212234244454444445-566457453C1-B44756777856632-1465767775D111111113----212--1------1-----------1---111131-41148655655957277865555888857965554512655354334894732222111532222222131433355432322142211344111221543456451--1--111--1111111211--111122-341443532222223222213235123--12322------21--1221112132311-1111213131132111112554114422222222222222222311111111-2--------1--11--11111222213832--------11----2222232114211676659775474311122--------23332444444535632322222221111--21332343----------2-------------111---------12-1114-1111-3 5A448772J76276978DAA87BFEBC779A8A768AB899BA666ACAACBAD99A66AB98897AA3878A59A869689999C488IGB8DEG9AA7AB99DA2CbBRJOONINFFIDHKIfTHhG**U6fPcCJGFMHJMHBIJIELGBVHJGGIHLFBIFJDF8BDEHG94EEC*AB8BCEFNK9KGGCCCDEB * c.42 Arginase/deacetylase
[ 249] 1113121111111112111111123111112111111-222223322311111113111221113111 3442833322231322244-4422444444434444343416642224322-323211--542222223331---311121321111122331122---1522142313-11111111-11-1-1111111211112211---3233442222211112111121144432121111111113321111-1248888877997997982244338984223-2211111292433323332233333433453---22-1--111-122---12--11---12-----1111-----------------------213----443322222222122243322224231232221324373-2423214121132222211211133324212221111111111111-34235242132-11122154422211221213212132221222222142411111111111122----------------1--13111133335211113222224344222224144245512433324214534255333332222222332213523115122642223331353264554357488332212222222222223222324322224336332242333333344634433363431-12333------33462333333333333-3334343333333333333354334534433333333434334322333331-333353333363---411111442311424434222222233333222222233242323233462333322332-1--21--23433433533433443333333243222113-22------------1-------------1--------1-----111--1---1221 CA88FGC-gDF8CF99AA9AABBAB9AA9B9B9998B88AB89ABBABAABAC9A9999AAACC99AA59A8BB9DB6CDBBBABBBA99E9A9ABBBCB9ICBA97BQOQNNHIMNEEIDGDEWPCRFu*N1JHaDJCDKGFKIEFECIJLCWCPFIDBHCGIHB9A9FZDHEB8BCE*DBBBCQJNUBMFGJEBCFH * c.111 Activating enzymes of the ubiquitin-like proteins
[ 250] 22323122222222235555533322222322--3111111112213143333-24424241221244 4896857655566465566-63336564566633336756556848524562645246226343576755333335442112222544213313112--131324124211111111111111132222222253666672225435444421133333332321144732322222322224413333141133333344144544442221134411122111111114211111111111111111111142133112234511222221223332331111122222223222222222222222212122111222131144333333323213221111211112212521324562133333311363733311111124333222233322222222223-23322425324132234224443232121223111111122222222-23314321111111111111111111111111111133322133313344443333333355333323344345423122332434324412226222422222222224643326132231342322575655667447435373333333333332333333332354114634242234411313315111131341331-111131--11164445544444444444-4444444444444224424444444446555445543656566643344442144444444444411121111123222432233333413333313333333332233455552542332322222444444444224454444446278332323322211112125335532111111111-111111-111111111121111111156455444444421 2211A78-843266AAABABCBBBB8ADDABABCBDCCACCABBABBBEBCCCDACC9BA79CA97995C9BA69BC5ABAAABAA9A8CKEADEDD8D887CBAD3BC4UCLEHCD9898AEBMK7OCk*J-JCWA879FBAKBAC786EA7E9CCCBGDDBIED7KEFP99D96A8AW68599EECJCBJ6CACBBA * d.13 HIT-like
[ 251] 33111-3211111113332221124222225111111123222212111212-233353333232-33 438261122221-5421----41147-----3355521C73625322-1-11675222--343345856731111222--52622333665538441--4725643734111111111111111--1311--12143344111233433443222211121124225452211111312112452333322455555555545555557666445554553843443455552444544644444449666732742246-2-662223154286232433211113311111111111321113212221232222222225827833333332452277422255422444517812114313A9641444139336-1--176DDE2357989555565563657-7897685CH861EFF7898ABACFA94626489A9A858222222226883135311---111---------------------24565469849899A987333388HC776767A8GACDA1387578887C7H3C9242321132--2122235413335351-123223321333232449333324342533333333322222222231442335674654344444565354555465464532-12434------67645435556575645-55567655555755555557B9565455555555555555555A6644445225666666666661133222223332254992223351332332225565556353C499998CEF8B9E94AAA223223222234456666665566423323333411112224444444---1---1121----------11-----1-------41253242323225 23--464-941-334AA89A788HCC5BB9ABA8785DBCAADA79857IDDJM57B87B9BG6755524365365645667758B364AD6A796B798627987-3C5D9534652222543451734P3-3652642944562434253144845743B57854A35939B527A3M2235ABCMNAA653DDAM4 * c.91 PEP carboxykinase-like
[ 252] 33212323333333352322221221111-13111--------2123231533-21122112222-12 44A2722222222382344-44335G544545645456C94746A4333221525113--44625549873-3333222-1133244445453533---15-43A5745111111111111111464544333763226422234734455333554243334545364333333343333354444321323222222121232222232232222142111122222254222222222222222111131------1-1-112211-1-11------------1111111111111----------------111---12423422222222222333111131211-253344643153-231134--22755542222234BEC434A535333333333334-785674866443A99B556DB754B45665666577645444444445443534311-2122211--1111111111111----175A55454244667957446455885444447773465256553653358758845434334422222223343333C583432232333255544456533334C452444433334364666666664557563454755465422232233223222442471-15557------43754543444544354-4334444445444443444334546545755555555555555544433344164445445555511442222254445679611111111111111133333344546599A99B8A89A985979434423423222222222235344434444444523331144885577331222226311111---------------------27433433443743 1---664-7222554AABBCBC8GFE8A9364568657555769A8HBDKCINK9BAB8B984563655544A6987677555567556578A5658766878665-6G9F8D78BG8477777FC7EAY*D1GBL876688A8B4B976A69F7876A563677A99BGC56D53685*4446678FFCDEA37656B * d.160 Carbon-nitrogen hydrolase
[ 253] ------------------------1--2-------11------62-24---------1-----1--1- 34A2521222111111111-1111121111112444322116665331344242322111673254389A5211123311152211----11-1----------22112111111122222222---111--22-ABBA9---D364498741133------55346548------------11322--1233555554453545434354434454242421122222262111111111111111222221111111111111111111111111111111111111221111121111111111111111111111111332442222222422322222222241222433233343232222221-35-2----------22-----1---1------------1111-3-1-2--1112-111----12-1--311121-12111111111----1---------------------------------11------1------1------111-------12322--1115443344437234523421----------13771A513112-15--1-23232-2-122224M14-------------1-1-------21221122152-212-----123---1--21-32---1121-------3----2-------12-----------1----------11---1------------1-1--1-------------1----11----2-----1---21913------11-1111---------1213433332223411113211----------211211111-1222112131122211111112BA6555--------21-----1-112-111---11111111131-1-1-111122- EFDFGEG-mGE977B67999BBC9B9978779877788888888997778D999677977778897783B98989985988888A87876AC7BEC66686B6EIW-B*EWVZPSVLIHEGKLGYSEWI**R6YNmCGEHTGIPEGJKEGLFDQINKKKAG8JJGEAOCIPGHKD6UcG*GGGTPp***A**NOYbVTa * d.219 PP2C-like
[ 254] ------2-11-11111-1--------------------------1-----------------1----- 3-32G4478891117A666-68--9j656667CBDB9Kmf1C3EHA914564LLQ758--11C4C7UNJF81---1----1-H-----11------------1-212-6---------------------1-1--13353---16----------------------11-------------5-211-2-624444443343444334C38824445143182-2222215B211111111111111211121-1-22---------221-----1111112222-11------1----111111121--11--2---1111292392223333131463322126322-16422AA2431-1251112-2-1-1B993-----52OGH--892372FECFEFFCDEN-68M66Q7JRa2-rZZOXVbjcdfcQK442GFRGCLNFCF222222228551-4-7------------------------------14E2-DZUHNLJMILJF8884IIaXCA8867MDhKSSP24A99A8A68PAY8YR695----3-2222222---555-4E353442163331424123312-----115-11------------------1-----33646844C574454546665666474655----2-1------8BG95B4DBBDDDDDDD-BDBDHDEDECBDECCDCCECDCBC446E9FBEBFEEECBECBCD999CDBB6-566666666666---1-----1----45KC1114131222213329A8A84911-84CCCDCGFNBGIIJ5HIG----------334833333557563322222----------2--------------1--------------------------------13121--1- ------1-----12---------------1121111----------------1-1-----------------1-1-1-11----1--------1------11-1-------1---------------1-13-1--2--------1-------------523312---1-----1--------1--1--7-----2---- * a.78 GntR ligand-binding domain-like
[ 255] 1111111111111111111211114223324231122111111222121222211111111---1122 1344856666667757755-56447755555669896655354754342443444344--666285655652111222-11-4213223324-2--1--12322533521111111111111122334344333455555---5287878866666434454667655754444544444443212211132333333343333433433222233322232431111115222232222222222142232111-11-1---11111111111-21111111111111111111111111111111211111221112221-21111111111-1-1---1---11---11-121141-1111-----21-3336665233346576876567666888888788881777878775872AAA89AB99ABB67554568989966555555555777557662222222222112233222222222223246665544444344343422222235222222333335522222442222324422243323433333333344443211214444443352232322232543475234222233333223111111122333555554334446344444444444444544332-3443611122254864445545555455-5545554555545555555666655444544454544444444554455543253444444444422323333311113254864445534432433433333332325333334343344445455222222222344464444444444333333333322222223555566111-----1----------------------1---1-4222132114411 --21853-A4626555568565776675443344443343333643548797A8686769A842322452642327445443333434237354744664434545-5P5HHNMKDE889A8B9GG7I6j*91IBL799AE8CB8887B9DAAJAIGBI7C79B6BAB87H5988BBBE*DEC9BUELT9GFDG84669 * e.7 Carbohydrate phosphatase
[ 256] 22--1-88A8898988-43A4---62243232-----------11-1---2-2--------3541-34 33A3E226445212BTL55-5X11EP535558YVYaB9ZU3EBN544333328593422298D366CBBC5---------1-922122-----1-1----3232323-3---------------321526222355554311144GAD7AA625443232426A2AACF723222222222254334---2233333332443434343333333332422223------242111111111111111111------------------------------------------------------------------------1411111111111-2111--1-111--2--1122---1-11--------614B775-1--188FAH6354326322222222222186557B854A7-633586B6798C5D4353C8311273677777777266653431211111111111111111121111111122V*419HC9CJGIILLEFHHFMMIMIHKK6EPEf8NF924988BG7859EE6KF5A563553211111113333CA4121--1--------33425432-4444F9-1111111111111111111111112133322365317231111132211112132123---2513------3212-224441411134-344441244441444444365722243111111111111111144223334--232333333332---3-----332367479---------------B9A8A5A1426499A9797C4ABC967651--1-11--332331111123433536676644522222221221122----------1-------------------------1--1-2-21142-1 22--112-834-2385595A896FAAA766645223222222266544456AFB5584544512311112113121111112223222239455343334434455-6X9PDEBFE64345264A6392GX71A7923245466833523C1354657C78738675A36633645GG9*CBAHLJCHK5D8985575F * b.33 ISP domain
[ 257] 22121-11111111111222222122222222111121111112222211332111111111121111 3332444344443443333-333345333333333344683436333444444445333344344444444344433343332211-1333433333-1433334333322222221223323331222323233443244444241632212222223222222243223423333433332221122223444444444444446443444444433363333333334443333333333333233344534334344345533443333332223433433333333333333335455454444444333333333334454555556646545444434444224443233244333344444311132333222222322322223222233333333333-43333322332-333322323333223343333333333333333333334332311222222--111111-111111122122223322322233333333333333653333334333333234343233323332344333423333333333343333333312123233313433444441112314411-1111111111111111111-12226343343333333333443333333343333-1243333-33343644444444444444-4454444444444444444444445444344444444444445444444444154444444444433334444454544345344454544444444533333333324555455556455544556222123222355644444444444334333333433332232111111222121112132-111-221-21-11131121-22111122212222243 6545786-G6847776BB899AAEEEBBAAABC989BCDCBBC888A9DFA999A979A9A98997778788878995998887867789C7B6778668678CC955A5H8C986BB7899C9DD8I7c*I1GCH97B9F6BD878898F79O9FAAE57566688856I56965567z55655DAAF9FC6598775 * a.80 post-AAA+ oligomerization domain-like
[ 258] 22233432222322232123333422222322333454444443533322444436344432112123 4563424333332243333-362247333333555534D9265832323332354222227553979453311113111223433432543514331--453445353322222222222222233343323343343233332356556653344222224563344464222322432242232222222233333422232324222222223232222221111113223333332333333222222122111141112222111123412222221111233323332323321111111111111222221222142243555545633333222222223221223333233342332224222444122222222558663224443512222222224-44544633242224423363343465222245333322222222222522224244422322322111111111111-1133323265435766689988AC8889997A9999879BA6A88127777546545484444A644465333333344558A265453444554443444533334446446444333333333333433333333343665555433335465556356555555655552-3554622-22244545444444444444-44444344444444444465554485544444444444444445444444432533333333333223333333444473932656545333333443444444434385666676556677645554343243235333555555544552223233222222223724455441311111111211111-11111111111111111-123133222224443 1111443-522186A87696969BAB7888A8978776567568876768899967777686748345143264442222344555322AB9746974956A332313D7K789D5D675657ACC4D6NxB-BAH5335848A838455B44D7A96CBJT39AB3343644753333I33333BADM9KM66A8EG5 * d.115 YrdC/RibB
[ 259] 2212137777777777248373677777727766666676666666677566661111112668-166 2236938544448388888-8822897777788888788839A832223111333223--88B8AA9999811111111226622213772726671113423383413111111111111112782732322776777732431778788787776766663779887766666666666666277111384555554444455445534444545888831266666684333333333333333444431111121111111661111111111211111111112111111111111111111211116111111111287787777777777677777788721116677789772168774221662213444111116886622388888777777777772C7677B77282-888888988899674329988888A897777777732226838--1-------111111111111111----13A33333335999A999888899A98888789994444243374E7448A838344734449422433334434871662626666666626667676C722222626211111111111111-121122123225384336132443333644333443434A41-1247211111264336232222222222-22222222222222222227774477466666666666666664222222221932233333333221511111123162736221212111111111222222223333888877887888848881111111112333533333658551144444222222222634488771112112151111111-111111111111111111111166111112222 1111123-844122522223322232223222332323222322232423333424323232324223222322324222333423422362242H555223247311614142144322213287282Hb6-5293221323612212232243542513323131222622345445a4665475593842535365 * c.90 Tetrapyrrole methylase
[ 260] -------------------------------------------------------------------- 9AK-------------------------------------------11----111-21--11-----11-2------------64356GHFC-F13---4G1C7J9O7C--------------25257664468611111---2-5934553--33333533342C3482-4-----4-----2211--21413333333323333232222313314223142------8312211122222222212222-----------------------------------------------------------------------6116-------1-1-1222--------1-13211633224-2-----42F3DH44B21111AFLNRE7DKKHEE44454553446-MQJFOMLJ6A7-F99GDCCDDD798G588656555463344444444898865B711--1---22--1-221121113311-1-2218748866ACKKKKAA7666DDHGBBBB9DHCGBEDL-4DEF7BC9BME8796CGF8FBG8A11111119698AE848256955AB6631866778B78AA9BC61A921113333223232233338544B8D886LEBOBID4FCEEEJDLIFFHKDJOJNH--1B549------B6887D8ABBCABBDAA-8BBA9BCA7B9CAAAAAABEED993479858999999769688B96875882-788878876777--26343336878FAF761111111--------777774C332C9EFDGCDEGFAEDCACEF1111111119356A66666BEA9AGJA8C8879A654543B7CC36EE11121222---------------------------------111117D84 -1-----------1----1-----------------------------1------------------------------------------------------------------1-----1-----11121-11-----------------------6----9---------2-----------4--9--1--7---- * d.225 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
[ 261] 11112222333334221321122242221242231111111112222121423232222223322-22 2432923322212344434-34114432333344444585265794332222876322116452557C6633222333334351111133331223---1322144414--------------122222212233355332224365553342244222222333444542322222322223431122223544444444444444445556644444434555555554243333333333333333333534465233235433454443324545554545222222222222223333333333323333442333433322222222232332442222322344221133112123112221212423333711111121331112111111111111112-54244244354122233423322334241113222221222222222133234331111111111111111111111111111114333312212222222311112222111111223222112112242213212311211112111111111221222221211211212211323232233653656112111211111111111111111114112213231233123333331333232222311-1311111-11132111232222222222-222222222222322222223243113122222122221212221222222112223222222221112111115444233221111111111111312222212111344334222332322222211111111111111222221312222222222221111112122212311211111112----1---1--11----111--11112311222222422 4234779-C66254A5455546555574455655555556555555675565854465655556544534754346636544445455545445469784354B881E88POUJOPVKGIDGLIlbFjJ**b5eLqGJJCOGHPECJHFDMGCkGHKKKCLP9FGACaADaCED84798f98678IHJU7LE77C9A95 * e.52 NAD kinase/diacylglycerol kinase-like
[ 262] 22-1--243333333211111222211121231211111111111111122111-----------111 46D5522422332384566-64229F66666788788EIF28385231144274422211355237D5453111111111215211112321--111---11214423222121222-11111121122111111655332211523442242211111211121344531211111211114442211151133333433233334431422133332333222222114711111111111111111111412122121111222331111242223332322122111111111112322322232232122331222311121111111121121111---11211211422211111222423121171365571111123LLM224E6AF44455454243719CBA676D5B81C44A55568765L91724655455556656666668442322211111122111111111111111111111235D11BHGBBC7BBBD68899AAHC99894ABEE8EH8153434675586B3C8551112112111111112214424342122112111112121112145445824111111111111111111111211122223232-131411111-111111-11-1-2-111332------1133--2-122-111---------------------113133-12---1-1---1-1-11-6----------11111111111----11111333325527---1--------21-44444121221454643968345642A8B1111111113111-------1---1132222111----111111113211111111111----1-111111111111111111111121121113211 1121432-K333--4KMULKMKHPMPSGGCGEFEDGGIJJKIICCBNHGZPdlrIHHE6DAAA86355662793A75255455577244EPAM99B564C46722314F4i8AB4973222343A7483Ku9-96B33337425424242442936A695775B48CD6DIDFC23554n6547BIKHOO9F4333455 * c.117 Amidase signature (AS) enzymes
[ 263] ----------------------------11---------------1--1---1--------------- -1-------------------------------111----------------1-1---------------------------------------112-------1---1-------------------------1----------1-------1------------1-1------------------------------------1-------------------------------------------------------------------------------1--------------------------1---------13---------------------------1--111-----------------1----1---------1------------------------------------------------------------------1-1--------1---------------------------------------------------1-----11---------------1----------------------------------11---------1-----1----1-----------------------------------------------111---------------------------------------------------------------1-1----------------1-----------------------------------------------11---------1------------2---------------------------------1----------------------11----------------------1---------------1-----------1- ----1---2-31-13-2-221421-112121113113-113-12331--111111-3--1--2--11---1-----1--1------1--3-222--------111---3-*******hilkkwj**c*m***1***cieh*jn**UmjgXsbc*n*roqESRaeXPNjOO***N7-2---2-21-2334-431-3-113 * a.123 Nuclear receptor ligand-binding domain
[ 264] -----------------1-----122223323111--1111112222222322--------211--11 4362422233323233378-7533357777725656434432223335344434433433434454334534444455323322233244543544411444644454555445453344444533433333333333342224233333333333333343453345343332333332333222222223333333334333333344443333333324334444443454444444444444443333445333334445544334334343333333333333333333333333333333433333333333333323353555454434343444333333222432244423242223223222526344344534344454535555544444444444-55356345453335544443434433544443435445333333333344333332223222211213333334334444222223433366654677667555554454555533775864533887353333433563532344445444444333554333243322311113223244222222277242222222222222321222221222445556566555566555655555655556562-4776621122255567555555555555-5535555555555555555555555556565555555555555566566655255555555555522765555544445555655544455533H555444354344355555555656656655553343433434655655555555654344443333333333334445444443433332322213-333333333334334355422222222224574 24233321A33333332312254432112111142221213312224541522443733363152221-23213413332111122121223232312211522232273DE9BBK89588879WN8C7U*B1F7I8786D86C795757I45CBCB7H37J376G233259EA43232G32454524934354A5262 * e.11 Type II DNA topoisomerase
[ 265] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3----------------1---9--------1------1--------------------------------------------------5----------------------------------------------------------------------4----------------6------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------3-----------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AB-111h-C-12--3--------------------1------------------------1----------------------------------------------58C*******nlffr*h**c*t***2***Zreq*q***PwpZW*cM*o*yvvBIhBMRA-F24O7AMM28-4L29443123--2--119129 * g.24 TNF receptor-like
[ 266] 33312-888888998A--22111-2---1---------------1--1--4----------1----11 3FD25-1-111---11111-13--571111144555137A342421---11-2121----11C-44D655------111-2-53-24---1-----1---113AB-8----------2-------1-1-111-5-899893235C-3434412311-------22-6365------------B774179168122222212-11111214---12111534224------87--------------------2---11----1-----------------------1----1---------------------1---1111-8L7AH89898BA7A955665122B3732458C9HFAJII4HED87793--F565443111--36PST6358A8F81211-11-111-KIPHJNJN8D41733622A8728FC635-BA1454488966666666C4431KB3------------------------------3782-8B968EIIIHE52221IIJF222213C8JJHJ7-5BBAB7934I28CF266B3493C4--------117AL6BJ8E7HD6LLFGF1DIFBGDE8D4444B77B6-------------------322--22GA2CAA63B579EBCCBC7BAA6B9667II---1255-------1--21-3332322232-3333322323324332331221-------------1--1-1--81--1112--113123312222---4--------121D46---------------1112114-2186BACB47E9BA7A76534---------452478998865ADE33565663331111--G55544331--11111531------------------1------BG4EF7AA9A27-- ---1321-711-22-323221312322333333432132231233324131534122122322-12-1-1-112-1-1-2-111--2-12522216-11-143312-389I36559P85544A4CH475Ei8-76D2533924B435744F52F4825A4AO2D85EFCECN5C6-23-D1--33BCEF2I94353132 * d.133 Molybdenum cofactor-binding domain
[ 267] -----------------------221112131--1--112111211121-2-31-1--1-1------1 214-542877726254233-3A--3433333295758958234444756774A56332--2368323563222222328-123221112223-211---1423224332--------------132233322233555441116142333221211211122221255321111111111114732232-758777776A9887776AIBDBB87876996A46KLOQNL7739A9A999A9999A865667F324DK42426DC22HM2345254776A67777667CAABBCDA9BA777797777777766622166683746J66678666652Q33245532223455115211212213AA833141-33222-----322222242222212221122226-46146451442-222133344121343-33145534343--------11112535------------------------------121311111374477633332AAA66666267684143-2764243325333214-5212141111111124143412431213-2111--111111121222212112-1-1121211-1-------131121198C212312251111122142222212412--1234411-111D735394FEEFFECCEF-DGEFDDBFFGEFDFFFFFEEEIA9342FACBBBDFCCCCECBD8DC9CDBB4-656666666646--22---------135514446441111123464334423223615665566655444633411111111119AAEBBBBBBCACD553333322411111-1522112233323222--1----2-1-43321444145341-----1--1----3322 ----322-4211552223224323243222222442122221222322222232322323332222222222222222222222422333522222222224122213423232244234223344474JRB-78A3223342E5-333132572232244213223935623342351K1132672242421354451 * c.44 Phosphotyrosine protein phosphatases I-like
[ 268] -----------------------311111-11-----------1--1--------------------- --------------1------------11-1-------------------------------------------------------------------------1-------------------------------------------1----------------------------------------------------------------------------------1----------------------------------------------2-----------------------------------------------1--------------------1-------------------------------------------------------------------------------1-------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1---11--1----1---------------------------------------1------------------------------------------------------------------------------------1--------------------------------------------------------- 1-1111------134TRPIyxmdm*luOOGNCIMIGKNIKEHH9EDNKj*zk*ubhPLLLKPDHUFGG6JFKWJTLNHQOGLRTIU5AA5ICR8MJQILG75MCI9125B*DCBBYHQKSKC7B*XRyP**j3kXmjNLMNBNYAINJ97eKQ*IBHVN9CK58M44B8D635E21111-----16ALGKC4-22212- * g.80 AN1-like Zinc finger
[ 269] 111111---------12-1111242--2113-212--------1----11---111222231--1111 4572732422223222222-23222222222232223833622352352337384344115452823667212223443333212212557714441113433245442111111121111113211323432342222335632C655444223355564434243333655545555555634112233356787997867778B753564677833437224444446645555555755557434453532232223334422243322343233224463344111112113227766546554655377443877234357444444464654775876636255673466644334321112222414944314326437676474634633333333337-66465D548772655B545646744B4343273422252555555554B9455352222222222111122111111111111139B5624423622352462222554423233227324252356424B85A453422243428455754434252724476424384966883436635428335345364121215134212111111122233534442458244428EJ9555955738473351-3244611111137223834885494A47194483775459A635445776433339442424336256644655443343815333433336351152444437789334CA43454445454548474685723123256896A69388AA3BAB2222222223553546476533554334433333743522944444452222232332212-1-----1-1-111----11---22224233222522 3113222-622-543233343431342332334333144444433342234243332321313333333333342332333333333332733224333334333112D37342253334245483352CJ5-4584144324523544543344544932227342433645734564X3446698GM3CC6655535 * b.87 LexA/Signal peptidase
[ 270] -------11111111-1------1-11-----11111111111111111111111121111------- 1231112233121222233-33222433333233332222121221111111222112--112134222211111111--31211111---------------2--1111-11-1--------P11111111211333331112111111111111111111111122111111111111113222222--21111111113111211122222111221421111111141-11111212111121-11-1------11---11-------111111-------111------------------------1--111-----3121-------2-2122221111-11-322112211111311113---1311222211121322222222222233333333334-2222222334212443222222333232122211112231111111111121121---11111---------------------11111222222333333123323332333314322222211222113222122531111111111111121111111121111111111111111111111333323221-111-------1-1-----11111111---1111-------------------------1111--------11------------------------------------1122---------1-------3----------------------------------11122---------------111111111111222222231221111111--------1----------------1-1--1------11131111111---1--------------------------------12--12111111- ---1CC--321-11333F74554745454445734334432466449659656855642322813122133321211-113111233232D4334611222314J7-49j*ndYWgoPQNLRvX**O*M**p9nf*OSSIjOasZNVVOMdOJ*SYaXaZcPK*U*8IELODMPL2621G21143J7GS8WA6259761 * d.154 DmpA/ArgJ-like
[ 271] ---------------1-------------1----------------2-1--11-------------33 3773433333333344544-44335544444544444445366334343333434333334436667444333333333333543444333333331--3333344444--------------2333333333346336633654333366333333333333333663333333333333345434--3344444444744444444444444444444444444444433444444444444444444443333333333333333333333333536333333363333333333333336333333333333333333373363333333363639933333334343343336333474474433334333333333333-4333333633333333333333-33333333363333333333333333433333333334333333333333333363363333333---3----3---213333333333333333444444333334433444434433333333443333333534334334334333333333337333393333333333333774333433445554433333343344333333333363367443333333333333333333333333333333-333663--33333333333336333633-333333633336333333333333333343333333333333334443333333333333333333333444443333733333333333333333333333333343333333333333333333333433333333333333333333333333333333333333333333333333333336---33-333333333333333333333433333334433 3333334-C6R34433333433363623333333333323313344313333332333333333333333663333665633333333333334453334354438-3589NcHHHQ47D8797B76B6Q*8-B8H5847B858576875848C87977-9R34654T647ILC33333*64333E8EO4GC169334F * d.130 S-adenosylmethionine synthetase
[ 272] 21-1--1111111111-111111111111111121111111111111111111111-121-1111-11 1121222222222222211-1211321111122121223212221222222122222211222222223232222222211211211111211111-11112212312221111111111111111121111211122111111121111111111111112111111111111111211111111111-111222222221222222111111222111111111111111111111111111111114112------1---11-------11-1211111111111122121212111111111111111111111111111311111111111111111111111-11111122112212111211-11114111111111212222222221111111111111-11111211111-1111111111111111111111111211111111111111112-----------8-----------------1111112222232222232222222222222222222221223222222222222222222222443323322222212512311111221-32312121211112222111111111221112111112111211332222232233333332333333234344112232312111133323343333333333-3333333333333233332344333333233333333333333333233332-2222222122221122111111111233122222221221122222222222222122233222222222232222222212233344322323434432442442223333112111111111111111211----------------1----------1--1-1111211 8846B58-YEC4A6E55678B9A96ACBB99999A97878578AA97993B9A8AAA7796688767638A78A588378877877AA9AD85A88CAAA8A94694CI2hNRLPHKCF9ALGGkZ8dC**J4ZRYD7CBMFBGG8FFCEKBARBEGEKJXZkGCGDXOMyGPJE78CD*FCD9DCCFN9LE79AEGB6 * d.258 Chorismate synthase, AroC
[ 273] -----1-----------------35475344411122222222443443332213333333-337211 1111111111111111111-11111111111111111111111211111111111111112111111221112221111111111111222112111--1111111111---------------11111112111222114441111111111122111111111111111111111111111111111111112122121122211211111111111121111111111111111111111111-11111111111111111111112111111111111-1111122222222222111111111111111111111111111111111111111111111121111121111111111111111111412-111111111112111111112111111111111-11111111121133322222222311111111111111111111111111112-11111111111111111111111111111111111111111111111111111111111111221111112111111211112111111111111111111111111111311111111111111212112111112111111111111111111111111112221112112111111111311222111111121-1111111111111111111111111111-11111111111111111112121111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111112111111111111111--1111111111111111111----1-1111111111-11111---11111111111111 66337774RYD89874855786775785645555655545455555557776A8566365554335444445444453453333334557B788785444554AAC35WWfTXYUUFGILNMMYQVGyK**P-iUyHIIHYJKbQ9GIPGREBYIUFMTGHpEc*DEIEGmEIbF8BCA*99958bIWc5Q*78EDHDH * c.32 Tubulin nucleotide-binding domain-like
[ 274] -----111-------------1-24222-223-------1--122--2--311--1-1-----1---- 22525---------32222-22--2822222252224444-127-1------232--1--323-313232---------------2----11-------123224-422--------------3--22231-3-3-22-1-----521---2--22-12-2322-3--23--------------1-----22---------1------13---1--1-23----------32---1--1-11---11-1---2----------11-----1----------1--1-----------1--1111111111111-11---111--4----------2-2-------------2----432---1--1--21---3-94222-1--13353322-22728------------871434-3482-444433743444212232241222335--------2---2--1------------11111-111-1111----22-2-211--645666233334431333333362-533-2433342----312--42--2315-------412123-243--3---3-----12214224113113212-1------------------------13254324212444344426664351-413----222------22223422443232232-42222222224222222223332312-3222222223232322322-2222--144444434444---411-114544--323---------------4333311---4511213331389833343422222222--11143333352661232522---2222--2-221122---------------------1------1---1---------2---22-1 31-1236-A3A44387AHDAA99B8BB5568556658766666685969AFGDRCCD979995122131211333154262332221-1LBGA9562233535546-4K5uHG9DASA98CFGCJJASB**S3UFT9CACIBCGG7EAD8DBAYCD8A8Jgp4DQ*aFLMgLKD339B7k6B548****C**AJFA9E5 * a.93 Heme-dependent peroxidases
[ 275] ---------------1--------1----131---1--1----1-412-422-11131113-----2- 123-4F354451-134612-1511541111113DFC5P562I563732-321888-12--115-4244581-111-2---211-111-2142-1-----154715-24---------------31112122122133321122B1EF84A6B33221111114583BK9C111111111111213112221243534424313971541132233322323143----2-231212122-22222111-12-22-2-211423212212152---1-1322312221211111311111121221122121-211111111125-1------2136231221-------11-2--1--1---2-------1-3131331-----221333211211222222222222-24328923411-1113112125311112112543311112222222212141312------------1----1-------1-1-11111-141271--2--7----3313-2----293--1522336443129H94311312-111122----2-3231-42323121111---1436231316DBPH57-2----1141111--1111111----1413314224-5221557433442353233224---3122-1-11131242723A82366733-6412797233944222224652226543534445354343344443243331-454454444754--P-11111---133711---21--1--1111-11221112215-4554328634636453611111111112233212213437344535332222111--4-22222211111111214------11--1----------1-----3-1-----16-4 --225A6-B2434373255354354452244343132232132222354445735352532222421231131231131143222322235225165623733V54-EF6kPSMSeDIAD8BEFbPDSEy*N2ONV8EHBLJGKD8GBFAM9BWIIEHQBDIJE8U9MFLJ7FD827E5S46444RGNO4QG555E7AA * d.4 His-Me finger endonucleases
[ 276] ----11-11212--1-1-111111311212-2---111222221213111231--11-1-1---12-1 1222222222222122222-23223322222133333344232342121332343322113223314633222221111222221322223314111112332142423--------------3422222233-325525333315544444112241333345223343122111121121121--111334556566664666665134433666355524366666667133333333333333433432222342212233222242322324522242223222222222222223333222222323222222223132333333333232133333332-1111333122232112221-11322214344211221536563232334344444443444155856754383155556676753554231212324413133333333333454622222222222223233133332331222221334-3553455555557566556877774656879893476756555766584655323242111111125633437471243143334243433324522332332222111222212222222221122133444322236443344436444445344434311321122122245344444444444344-444444444444454444455544442444444444445444464433334334444444444443323333334655345362222222222222224443444332546666777636665466612222322212113222224322245555555553333221111--21--------1-1------111111111111111111112222222221211 4322352-G691126EFMBK9A9DBAF97879C9D969B86779AAD9GJPGNJFKGKBFDF6466544471354671654444433344A5FC583564432897-373656786333834749F4E2AX7-5692435943643422243274434333165333923523653793C-12--454AF5567869A2 * f.17 Transmembrane helix hairpin
[ 277] --1-1--11111121--1-----21--1-2111-4121422215623337DDB1--1-111121---- 7GC3I325775243EHJ87-8F22II77776BKHGHCDOH443O34421432434323--46C1727BDB13555111--315--1-1225214111112626683434-------11111112211123112321442211132512411-1112--11---1122391------1-1--165432--1113333332533344226323322245-22221111111293-1111111111111111113-21-22-22-2221122211-1-222222----12211111111111-------------1--111---1-22153334354331-1221111-1111--2--4411111121112-1--416654411112A6REC4376467533333332324-22922A2AB981CBB7BDBEH9CC9734469G757787B555555558752662311111111111223112222222122111113A516DA6CHHKHHL98889EEHHAAA95CIHTBGIE23FF94438684F7F917332226444344441147441A332334156116-63342374234525624--2---1-2---4-------11134645374336462234344243454242312261-3133211111158233353444354533-4333444343456333336CDC5532331232232223222326334333221544444444444111311112545522225444626122122231557453443271666675A55677A6755311211111111151111114332774363333331111124111111------------1-----1----------1------11111332331641 --11111-1112-3284676685574822123222-24344442222313479B332532-1-222112212111121121222326114334324-1121142441142857445A4455554645D4Lk81DA86474765C647555742A446461333511132143232---1-21112111484-1443122 * a.152 AhpD-like
[ 278] 43--11-----------1113-4-6111C424---2V9------1-1--1---8GDH4M8C------- --223422335161-2244-4333-344444-34142224132121112111-241-11121263224333222252241112--32--------------------3------------------1----114----2----4--135---1111------1313151D-------------22452-3158999999676997A88C9CCBBA7744525AB466738235AAA9AAAAAAAAAA66889BB11761272BHF117B436543434666655555566666576656555554555455557756377751117JCCCEDCE9B81G333798223514232222431111215421-25-2-244----------1-------1--1---11111---1-12-------------------1---------------------------1--------------------------------1--------111121111112222112111211--1--1--1--1---122---------4---------------1-------2------------------2---------------------------3--88A2------62111112-111111--111---141411-1119F962E5877899A988-7788989889798888887DECDC6664644454454444444976499972-A44334443444--1-11111----1----111352-----2--5--------1-1-11212423-------------------56665555556744------------1----9------34233333--2111-C-328273323338734322211111121-2---- ---1-5A-3312645115224421112MLN46A24221-11112335W21312111244211G-B-3--1863-23N2226---222-51111123131134164D-623HFFGSGQA8AAAEEVT7RCp*Q8ZJU6A88G9DHB9BE97I7ASADC9E7GL6E752A76H9BB5-366K12-23G32F34B-1776C7 * d.95 Homing endonuclease-like
[ 279] 22---243344333332533333764443452------------2---112241------11451-12 3485634422491266666-A43334666663467654453444354243333353431132324364D51----1---241421121--23-3-----1----1-13---1-1----------4524543346523322---34431211111111111111113233111211111112144433---1222222222232332233233222234362212------213222222222222222221121-----1---11-1----------------1------------------------------1--------1-111111122-1----------1-1-71122EC23341-72-------17-43342322349534645333446665666666516767776867423333365575446734545873665445555555556622733333443332433333343333333333333446516444D655566655557779666627668657645796454556569557476-3285333333334474815A78666758668-A697B58-477675254657454465453633343334923422652553443358ACCB47HCEDAAACABB9--23966------9687793999999A9IN-999G99BG9K99999999889866857899999999988979878998888325555555555552224222223334545423433343333332232232222434435565544334454643322222222236777666667777666333333334444233-113331----1-------------1-1-------------------------131- -311421-3---2242373423132247633334454333334123363455555652311232444211411412622241115213214337243332322323115352586451421231621A1JbB-224121-612623411-2225152351-156343535*17724232112312257Q252224531- * f.21 Heme-binding four-helical bundle
[ 280] -------------------------------------------1------------------------ -------------------------------------------------------------1------------------------------------------11----------------------------------------1-111--------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------11--------------------------------------------------------------------------------------------1------------------------------------------------111111111----------------------------------------------------------------------------------------- ------2------------------------------------------------------------------------------------------------1---1K-*******cbgbfif**e*d**x-*l*YgZZ*ajxcVgdbUjcS*cyfjuLVd***UNmSM****--3--1---2--------------D * b.96 Nicotinic receptor ligand binding domain-like
[ 281] ------------------------1------------------------------------------- ----2211222-2--------2---1------211111121--1--3115543332-3--1-27111221--------4--1---------1---------------2-22222222222222212221111111111-----2--------------------------------------12-----1336222222434422225H786962425441824KKMOLJ321999898899999997333392-2CM2-424EC--IQ1431243445947555578B87878A7887555555555555524411-444A13-4E3333333625-S--1232-1-22312--------1--199712353-3111212222121112122131111111111112-11111222111-211122122211111211112222111111111111---1112---------------------1--------1111111111112131111111112111112211111111222132112111121211---41111111111-112-343-121-11111-12111121132222211-------------------------11868111111161111111111111111111--1111211-111B744454CBBBDA99BA-BD9BCB8BBCBBACDBDDCDAE66232BA8A9A9BB9AABAAA6B9688694-666666666565--21----------112144564622222233422222-2---3133333433333332343111111111-9AA8999998A9AB2222222222-------922111133333333221----1-1-44311444145322--------1----161- ----------1--31-113---11-1111--------1111-1-------111--1--1111---1-----------------------1--11------1------15-CJNERFFCEUEHMS**MZQ**h1gZbHSEAKBGeB6CJJ9L98aAABCA37PA9744G54G5B432---21-2----11--1-1-1-1- * d.112 Phoshotransferase/anion transport protein
[ 282] 11-1212--------1-12121121-----2-11-------------2111111111111--131--- -1--3-1-------23122-22--34222222221313541132-411111-112-21--2-1-3355641----------2--2-----1--11----121--21-----------------21---2----1-12312---31211-111----111111--112141-11----1----112-------1232331221322122-111--322------1---1--42-11-11111111111-----311-11--2------11-------------111--------------111131211121221----------221---------------111--11-1121-22-111-13------11-141111-----112111212111122212222222-22133112111-22212232223812112111121111111111111----1-12----------11-----------------2-221-31111211311-------1-1----1116---1----4112--2--------1---2-1-1-----1-1--1111--1--1-----111---1-111-144-1----1-----------1---------123--2---1--11211-2411123234231-----1-----------1-51341112121-2--11211-131111111----3222-1612121121223221111-111-1-3111111-1111--2------2222--1-1---1-----1-----1-----------542432-2-14211741----------2-1112-12411----2--------------1--2211--------1--------------1-----11------1--------2--- 2-22IMs-C5544567565455556742354353434444554543546885A756L86A87312111122121111111211122112AJ45CCD3344224313-J*Y*decZtiQQOOQXS*nKmP**c2iU*STNQbPUiQJWQPPdRMoRkQVrORUKaMA5J7BK6CJV-788O1--71JJKX8QS538GEBA * d.166 ADP-ribosylation
[ 283] 332-3412111111122-222223111-1-1144411-443319D45752CCA135-2445-3-3116 3--29122333432CFC99-9D33HM999999FIJIA8CG1C7B31-1-352112322--78B2F6J4AB3111112221483221--CB871A55---4623454512---------------65378435435233122236256553331111-1-1--31437676---1----11-144333445239DDDDDF9E8BBDCCB466668CCC312A465677655H85444344644444444445543225424525553345323221668333333324522223212222333333333333322233311122D8FP89788A81817D6522339134624245BC334438223222233223844311111658AA2116344633343333333-43633933445-4777443545437A44324523322345455555515643342-------------------------1111-44551255366339538577799BA77772876A3997133363525475666-63526456244333331-14453JDF65A93A6666335357557824521B6511221112311112222-2222-3132333444423333222234522222255235--151-4------44433434445455444-4554444444444444444444442133323322333333332233434443-211111111111--12--------1536365554452222232246676627335927777555366454534622222222232333333336644433333332221111114222------------2-111111-111-1-----111--1---33122444342363 12---2--3245---214184323332113211321--1--11121233312661-131111211-111-31-1-421122111--21113-142322211-3-12-26362121211212122121218H1-426-2112121222131211122321-1-141251124123--11211---142-71523565453 * d.90 FMN-dependent nitroreductase-like
[ 284] 11-121----------11------2113-54----------------22-32221112212---2--- 227-92112221212-111-11--1211111-1---3153163F457-6651AB9-------21H14DD4284443CA2----1---1EFhT-B-----3M-92P7M-C----------------1----2----699651--3----1-----11-------1-3--1-------------42-1154-638111111---11-1--94BB3811-344-213222222-b11111111111111111111223-21-32-211--1211127-2122221111344233223322231111111111111222111222362-D8-------3-3E2--1212B-71-23621-----22---433A--3--C6333----1312-11--1-11---------------3--2-1111-1112322332112-5-1--1-------111111111332---1------------------------------16363-----22222312222---42222-3-2---------111-------1---1----------1------1--1--3-1----------1-1--------1F1-------------1------------111141-G-16111---61-17766--1-6------11-------2213-45111-112-2--1-1123-1211-211-11-555662-111111111111111113--11111--122222222222----------------12111111-----1--1111111-1--2G--2112-1-2--2-5433111-1111---1-22222-----1-87777666------11-1--11--------1------2----1------1-1-11----3-32624461R23 111131B-QB1----LDNNMSUHQFPU6633222332222221221A835PZgmRQTMD9A8323322422-31323224222322312716D7L-1312247164-7K2CdZWYWTGEEDFKIudFqF**L2eNxAHEDUCITF9FHE9RDAdGHDHN67C45435133326641572----87MIEMMHA35GAFFB * b.67 5-bladed beta-propeller
[ 285] 1--1------------------1----11-----111----------31133----1----------- ---1111322121114422-24333322222353324433-23211111312211121--11522123121-111---------1--1213--2------11--111-11111111-1-1111122132211112-----11-1-1352224213321121133235655-1-1--11-11-------1-11312122111121111221223423112222111111111122232322222222211122322111112122211122121113123332222222222222222222222222222222232222222211112222222221122112111111-21111-11121-21112112-111112221-----112111-12111-11111111112---2-1----3--122-1-11-1-1-111--1-323323---------1------222-------1----11-------------1111--211-11-----3----333---1---123-1--12--11212125--2-111121222-------1-61-322111121-1-----412111-143213-23131--11-1111-----------1-1--1111312111111121--2-11111131-------2--1----23-21313332322232-3333222424323543552444713A12222232222222224-3222223--2---------------11111-1---211--------1-11----32113123211-121112111444411111111111111-22-54443111124445455452------1-11------------6--2141------------1--1------1-1----1--221 121-412-1-1324-3124--2144251123111231----1--1-41336253421421-1-12111-11-1--11---1--1-31---111511112--132-11-J6*tptcgYVUOLT*P**TxV**v1yh*NRSVtRUtiBUQWKkOJhMiNNO97D5GMObMBIMNU761352R444458AEH2ADA44365B * b.60 Lipocalins
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p7-99G64558545525866653A5435524358432522413531122S1121285EA5581345478 * d.54 Enolase N-terminal domain-like
[ 287] -------------------------------------------------------------------- --------------------------------------1---------------------------11-------------------------------1--1--1---11111111111111--------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------11------2-1--1------1-----------------------------1--1--1------------------4------1------------1-------------------------------------------------------------------------------------------2--2-----------------1-----------------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------1---------- ---1GD7----1HGP34444665647755454543465454455556655568B4475565643554435334542323333453523343344345365454KFJ-G5*T**s*rweZZ*dZd*wQ*V***3*n*WUTWqWcwWRcYXKrWTwZuTdbNNbJOIKBNGHOIZEI--1-------1-11621-3GNKNA * a.91 Regulator of G-protein signaling, RGS
[ 288] -------------------------------------------------------------------- -------------------------------------1--------------------------------------------------11-------------------------------------------------------------------------------1--------------------------------------------------------------------------------1-1-------------------------1-------1----2-1--1-1--------------11---2-1-----------------3----------1--2---------------1--------------------1-----------------------1---------------------------1-1-----------------2-----------------------------------------------------11-1-----1-3---------------2-------------------------------------------------------1-------------------------------------------1---------------------------------21-133212123--61---411-242311-1---21----32-1-2111---1---1-111--113-1-------------2---------------------------------------------2-----1-----1----------1-1--------1----------------------------------------------------------------------------- --11--1-----212--21213332132-3222-1-----212-1-4311132333-24244--1-----2-2---1-1-1---1---1-85-2431--2--123---*1*WNUNYYXRPTVVM*kM*R**lA*e*YQOQTVgaPIZOJHUKK*MNQKN96EANIAGRIeC7I841JVK*CCAUa****1**4P3344D * d.10 DNA-binding domain
[ 289] 111343131111111111222119KFHGJKBB333432222216346857CBA24443433--12--- 122154422222-133333-34116233333542223454343454432223334482--554341647932111122123364-622KKIK3I662--52-A4232G2--------------111---32--26AAAEC333527C88A963244444455675875614434444444444654411-235556565664666666364425666413554411111123322222122222222222223322232322255443223143-2225553222455444444444443333232232233522444222316413775777737434334876375456441444282446162112255149211224444-16--2-------444422244-5-1-41-3--6-9--4423424446544456A78686676622222222-----454--------1--------------------22422245522-1111-211111143122212113675611111212333111112533-1113333333321-57267JB96H747C335526363A39234466777223421111132222222224455711DC4781775676766757677765767687--45636------97557A48888888888-88488888888888888889997744699999999999999999888888832877787777888--3822--222-227673666456233336446--2---11213455555433C5655B3334322244233888755555898772224244222222244B322112211111111541----1-1111111111111121---32222231221974 ------4----------------------------------------------------------------------------------------------------114----1--1----1155---------3----4111------1------11132-1------2-42-2C54P465518466-364553-26 * d.286 TrkA C-terminal domain-like
[ 290] -------------------------------------------------------------------- --------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1----------------------1---------------------------------------------------------1---1---------------------1--------------1----1--1111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3322--5-51----1---------------------1----------------------------------------------------1-----------------2Q-*o*m*r*iYfTerY**V*n***1*n*ZZZSzVa*vNecaUxQS*W*jokYSUDsW41222K37NU-222S535-2---1----611115 * g.14 Kringle-like
[ 291] --11--1111111111-111111122222121111112111111-11111231111122-1111--11 1211122222222221123-2122122222212222232221212322122132111111421122111122111111112111111122221111---13222311121-1111----111111111111132122222111111122222111112211211213211111223211212111111122111111111111111112111111111112111111111311111211111111111111111-11111-1-11111111111111121111111111111111111111111122111-1111111111111111111111111112111111111112111222112111111121111221233321112123442222333222222222222-223224232322322233223211222222222222222222222221222221311222222111111112121121121111211111222222222222333322223333222331223112222213221121222222222111111112122222111111121111123222321212222222111111111111-1-------11111111311211111212222111111111111221-12221-1-11122222221111121111-11111111111111111111112212211111111111111112112222121222222222222-11122222222222121222111-1111111111121112222133432222322222222222222222111122222211112321121111122221211221111--------1--------1------------------1-111111112122 5512FQC-H66387776767977666666666676668787AA6677596678A776699888655652L6554458466555677766697677F88867F7DDG1CPBMOVPZZQGJFGHKIdSFYE**N3RMdBDIDQFIVGDIHHHIDEQGNGIJAKJBB9EAM69FCE995898L76767DOTS7QG46LNKI6 * d.143 SAICAR synthase-like
[ 292] 22----3111111113-1------1-121142--1112-----231121-311122332231221-11 7682831543322234411-14--45111115433357F9445364335554354255224443536794221112211-135432322121-21111127155A53461111111111111122223312222233344---5343353323322233334423246713334223324423533323321422222222122222232775422244236453323333233333333333333324433311-33-22221122332-11-1333222211111111111111111222212211112211211222221112------------1---111122-221-114213214213111-21-44395582222246B685476457522222222225-89489586485-87759899AA77465132832423233333333335354335311-------1111111111111111--1-13142234434EBDCBE6555588BC555525A69659645554754556465A366633424422222223345588231-12142622231212-2-2-46436225---1211111----11-11-343212244-351545732333344446543334436--224-51-1---44551444444444444-44444444444444444443435533445444444444444442444444411322222222222111211111222337588---212-11-1----666663546363555557C76777666551----1---42332324325644466565655553333223-331122111111113-211111-1-11-241-1-1-211---13111121112635 5445557-LA71333564433344245453333333443434445423445545351453322321---1---211---1121223323464647241333225451537ABF8CC55552585DA4B4Ge7-98C3665F58F835564953B6A56B35664348968833964565n56474IDGH5C78395974 * d.227 OsmC-like
[ 293] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1----------1-1---11-1111111----1-11-1111-1--111---1----------------------------------2-222----2-111--232****y**UDENX*R**F*j***3wu*AQIH*YdvYEgIGC*D9*R*v**mwlBbA5E8KKAPbM91----------5141----16241 * g.22 Serine protease inhibitors
[ 294] --112112111111132311----11111113-312411-21-13-2--2234311222-1---1-11 35718124333232-2211-13222-11111121116-112433-1-12112421-----2221A-28953----2211312112122331623333115737672813-------1--211211212-2321436563211-426241-12-------1111--11263-2----12-1--3432211-4224545545616453442244346551111113------32--------1-11----211-1-1-11-----1111212-111-1--211-111422-----------2222222222212244111224-2328344444562523-4434453112313321233131425422321-4442522532331124643352335333133332223-24432345252-543254356522441114315355213111111111221341312-11111------22121-1---1--11133332333125445444333322233333223645435--675622--143341244121222111111111537465544242337331176734765445656532131112222121111111113123242221245242121344311112224321114--152-3--11112322412-----------------------------144322-13322233223121312311222--11-322222222222----1112112123454311111-12112111144444341221254453464336333333523223222211212222233123232534433423231124222222---2-222--252E32-111112-11112-11-111122211-11122-2 1221559-L73835A89KAC9D9BA467AB77CA7957372553548CABAB8C67DLBACB12326346437544D-14354433343CM59A9J6A8969365917IGPCDEIDI76548A4TO6D8j*L3LHRAA9AH49I849886F56BBB88C35C87C36C58A6BC74K969--68CD79AC9G626B7CD * a.111 Acid phosphatase/Vanadium-dependent haloperoxidase
[ 295] -----------------------------1-------------------------------------- ---------------------------------------------------------------------------1----------------------------1-----------1-------------------------------------------------111----------------11------------------------------------1---------------------------------------------------111------------------------------------------------------------------------------------------------1-------------------------------------------------------------1---1-------------------------------------1------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------1-----------------------------------------------------1----1-------------------------------------------------1-1-----------------------11--------------------------------------------1--------------------------------------------------------------------------11-- ----------1----1-11-1------------11-------------1--1--22---11-2--------1--1------------------1--------1-----2--a*lI*TaTbbinQ**X*Z**l-***SSUadWD*zEQtUs*WJjTOMKe---1-111----1--11-2-1---12-112-11---12-- * d.19 MHC antigen-recognition domain
[ 296] -----------------1-----11--------1-----1-------------1-111---------- 1-1----------1-----------1----------12-------1---------1-----------1------------------------------------1---------------------------1------------------1----1-------------------------1-------1-2------1------------------------------1--------------------------------------------------------------------11--111111111--------------1-------------------------2----111-----------11-----------1-----------------------------1---------------1-----------4-----22222222----1------------------------1-----1----1------6--1---1------------1--2---1-------------------1----11--------------1-----4---------------------2---------------------------------1--1-1-------3-----1----11----1-----------------------------------------------------------------1----------------------1-1---------2-2-3-1------------------------1--------1------2-----------1--1-------------1--1-1-2------------------------------------------------------------------- 465576M-cHD576847758797677877787767587675778778666667777866666965555-555655553655745658786B579695554676C9C2KbEsmmhjjoUSPSWVRuiSvQ**fIrZ*UPURfNVcUUUSSSfRUtQhYUTKbjHdPPFPGGYCDZK4DBA*86588E8FH5BF98abUWJ * d.148 Hect, E3 ligase catalytic domain
[ 297] 113-111122222121213222224112121221211111112331312288711211222---1--3 2231221344312122211-121142111112635357341424434412227251211133532134531233322213143222222221-122---2314324332--------------1231231132311112221222A52411111112123211112134---------1---132112215363333334323333332322243333544243444444463333333333333333332221212311111331144-1-131333222111131122222222222222222222322222322222231224533334332321311223212211311311123111211111111232142261111125456316325231222-222226-554454635432433246333233453137-33133-21333333334333385211111111--1111111111111111111-54482-11-232222231111334322221313C2334124B234143432333223332221--11112-3123322331221131222-4333225334443344232331222221-1-------21222554324B2375332222234232282223842--24122------22112222221222222-222212222222222222243322--22222222222222222322222222-333332333333---32222233332632211121311--121235455643-223133351433233466112122222222522252223233333543444433311111141222222111111111-1-----------------1-------22222212221111 1222573-844255677A978876797667778665787888977798778AA9689779996554443546564776764655465346D4766B6775556A7916M9KAH9CFF999BB9AHF9G9ZxE-HEM79ABH8AB989BB9B99HAFGCE9D8EAC67J689CKC54532G23336D9CJ9F956EA8C3 * f.59 Cation efflux protein transmembrane domain-like
[ 298] ------------------------11111121111---1111122111-3111-------------11 2791322133311122222-24115422222345556A882225472-2222855124--335131443421---1111114211111444413113--36256675194444444454444431121B11192122211333224355338273311--2113435446---41--2-2122321111121433333222222322243443422211233116666665614444443444444432223313322322-26511112111123332222222433333322333332222222222222333222333411122222222212213111111812111231111211111--1111122713A9A611111329AD1113113411111111114-333336315621645B66765855462621453134-311111111121121925111---------221112212112111112326311444386646926773443777783784255441533463311523252213145452121111121114212121121-2-44453126112124444781-12131212111122111111111112128111151221222221-122222211224--11111------66255655775555565-7566675666755555555656737848999989999999999466776584-BA9AAA49A4A4--331111111113282244453422221322223222221112355152254222222632111111111144663434489455333232233211111-6244335411111211214111-1-111111111111111111111111111111434 32--545-A14132355656555766476555568666668566556445677557455877524332123222532233333324323563544432333445361575C6876C75436674F8594ZmE185D375395FD96657575484568676957446648A56762231855223BBAH786137967A * d.198 Secretion chaperone-like
[ 299] 11112222112111221311211322233133--1-11-----43-13-1232111111114431--- 254-C12222323166511-14--48111112767623942B274132123-41312311314252649E2----111212131-11111----11---22-1-3121---------------11112112212122223---62131411144--1-12--1---66512222222222122211111-2-7A9B9BC98489BAB9233337A883224443222221461333333333333333111222213312111222222512-126752223111323222222222221111111121111222111---1-2456333222222323331121112121-2111232121413231-1--32522211112173G9B12321-4122222222216-988965982B31D9977789A9BBA43212451111315222222221342-32511--------------------------1--29-39CA56BBBCCB533337888554528B5A99FB-1445356338444I7-42-3538411111111-2142144-113--23221-67314551333238D553112212222212-------121133354-111333233222221133212212113---2323------77743745556587754-5565767555575665664999654446766666666666667B534554521622222222222-----211233331-645---------------877781522561DCEE99B87B8C94987144435434---1323223531348613133---1111--1411--11-111--1--1-----1---1-2------21--1---211222223237-2 11-18A5-C5312267BE78BABBD878955456766555655455A98C569857645523112111111143111111211131111A74B8523442321916-2a6A223221311113676352IcA-44B3222613231212221244232333356442643545342644h342A3556EC9486B5787 * c.33 Isochorismatase-like hydrolases
[ 300] 11-----11---1-1------11------1-1---1-1-111----2--11----11-11--1----1 --1---1-------------------------1111-2---------------------------1--1-1--------------3----------------2-11-1-21--1-1--132331---------11-------1--11----3------1----1-122-5--------------1-------1222332-5-2-21-12222321321122--1--1--121----1----2----1-1-3-1--1--11211--11---1---------1--1----111---------2221--1121122--------1-21-2---1111-----1111122------1-132-121----1111112-12-----2-11--1-1--1----2-----------------------2-11-----1-------------11---------------1-1-----------12--111--1----11--1-----------------------------------31-1-----1--11--11-1-------1--------------11--1113--1221-------2---1-----2-21--2212412-2-11-111112111-1-111---1-1--1-1-1---11-21122--3-11------------1---------------2--1-1---------1------1-1----1--21--1---1----------------------1-3--1--2122--1----1--1-11-1-11-3221221---------1---1313211-----------2---111-1112-2221-----111--------1-3333-----1---12-2----1--11-----1-----11--11-31-2-12--- 66325DC-L9E8BBD635B24645234117756338922231344456344577134127645543343631612342335231624544823267344-33245A264EuXWXWseMTJMMgO**N*P**t8*h*XPLUiJcoXJYRNOqPL*PfXXkIIIHLG9DLCIRDPJA3423F34532*BAC4HB4CFLII2 * a.114 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
[ 301] ----------------------------------1--------------1132--------------- ------------------1-1---1-111111----1--------------------------------------------------------------------11-1-------------------------------------------------------------------------------------------------------1-----1----------------------------------1-----1-1---66--11-----11-----------------------------------------------1111111111--1----332------------------------------------------1----11121--------------------------------------------------1------------------------------------------------------------------------------------------------------1----------------------------1-----1-12-----------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------1-----------------------------------------------------------------------------------------------------------------2--3--1------- 3311IHC-uQB5MJaORPLSPQRZTVTNOILKKNQGINHKGMKGKMLLMQRRZSQRMJMLMMFFE9CC5D87FBE56466BCCDDE697NiPRPOPMHLIIIIhee1BsJNGFBECFCACBBHBLO9MAQ*H1LEN9BBAJBEHF7ECA7KE6MALFGB788CKF9AJEIJBFMF8ECK*LJI7CPHWLNFFKRDGHGS * d.120 Cytochrome b5-like heme/steroid binding domain
[ 302] -------------------------------------------------------------------- ------------------------------------------------------------------11----------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1----1---2-----11---------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 8534JFK-aG959CFCMLA6A87A88987997A9666AAA7A9463F9EDAFCEACBAB89C744424225435434243444433355TUDM***2448K74DEC-FhG*UcUXVSLDICHMH*aDpH**b4oU*BIEDTGJSIDMGEGOFBbHXKKNFHIDQMzBYTWUDJL93*HcT776*OGFEMGHJCBGQPR* * g.85 HIT/MYND zinc finger-like
[ 303] 111-111111111111--------62224-22--------1---2--11-----11111211111--- 3432221111122222222-2422422222224333226623242242122178542222225238A3222-------1--1B411622322122311113222422221111111111111122222222222233333---343433333333333333333333334333333333333332332232222222222222222222222222222222222222222212222222222222222222211111111111111111111---11122212221111111111111111111111111111111111111122112222222121122212222111221111441212222222412113154333333333735433333343445645645561774796747P42FAB9B9CBAEEF99333AE86667JGP444444445333834322222222222222222222222222222A357323355355555564444556A55553557646432233753333533345223352533333333333333321322223222222143322221222223312121111111111111111111111133332323833433434433433343334443212333522222233333333443333333-432333333343333333333333334333333333333333333333333323333333333332223333334333333552222223222222224333335333536666666AA796638883333333333333323333334334533333333333323312222231111111121211111-111211111111111111122222222223322 54--453-A3413334454455345473343344443333333333453357555464345433523424433652423334345433335444352443233465-4B5L88688A6663575875A5N*71A8H46738656636546753A665585AA4878456A549764446U6575582394553752548 * d.250 Folate-binding domain
[ 304] -----------------------1464121312-212122222212211-1--1------31--1--- 3251711233332133244-442255444444433344983433423-2441464233--452162985633222222---15111-2442322--211141134252212222221111111111312111121-33112224133333332333212233333246333111222121223221122232577777778576557767225575631222--34443284-22222222222222-22--42--11-1-1-111111-22-----1-1--------------------------------1---------245227765557151-4321222525--212223322222511--13-422-3533222222226342235344466665655666-335336366732C9966BA96869633453473277256333333335333253422-22222----1111111111111222223573447776CCC9B996665AA7A646636D7877772255553155985466224222293244444423224232421222311111132322222233342221312221111111111111111212122642565846667854454644446466468223252222112153334336666666666-66666666446662264275B5434553233333333333333624454443132222222222222262222254443778B222422222222233888786456672DDFD7G8B5B8EB56771----22--23232555456865586BA9AAAA844442224223344---------------1-----1--------------22-33121212321 ----744-621111578736665HDB544443276666666672--2438CBMF66554113311--21-121-141112111121-13283843322214-7--6-2I4K5434522222142421327E3-33333323122-3322222333324922294533511255672334933223631D5864554226 * d.21 Diaminopimelate epimerase-like
[ 305] -------------------------------------------------------------------- ----2---------13311-11--3111111211111-31-322-----------------------111------------------1----1-----------------------------------------1111----1-2-121--11----1-----3----1-------1-----------------------------------------------111----------------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------1----------------------------------------------------------------------------------------------------------------1-------------------------------------1------------1---------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------ 1122bhB-E64177DEHIHQQYVbchhFFCDGFG9BDD9D9DEDEDKFHIWTkaNSEE9ABB98E9A6-AA6CDFHG2GHIEBBJN244GJAHACGEEG6CACJJI3PWL9A89AC755555A59E775JnA-955555455568254415527567647EP8FAFFdIH*BB718UKE*BDBOWuwz*H**FB****T * a.120 gene 59 helicase assembly protein
[ 306] --2--112211158A3-132122-211121211111-12142322112-2--1---111121-21--1 1B815312337216C4243-3711D244343457678DGI1AHE4234154398B334--443-32369512111411-1241--1-1543555222--22111975-1--------------3--11-1-2114-1111489616234444--231121-254-363A112--11-31--1322----1344454554DBE7AL49F32753667926253325--141975444431113332241D565612-421226--21121122311-2113122431122225222212122114122552211221115121-C2731215432533E9FD536322A3112CA294E47223113123--12-39333222-245C56EB4633343444444244B-DBGAAHBE6B41A445A4D923164C244B2A6832422HHHHHHHHEA772B25------------1122-1421111-2-43116D131221464446453333338E7635895BA463D114453296449312634C-31342111111178262722B14-552A2314185486532G36423612311111121131111121612213222141392212151747915332253622511--1311-------14243466763641574-7556363554735774774995324512411461251475418642534342-244434344332--B1121125445516211-1111231111311525434314333466333642211758932111111111421324234451112194943222434311B-221111--------1-2----------1--------------1-2-2-----73-2 --11241-412-2222334244323122244442112222222333426A537824433333211111111-13211122123211-11478392B2223231233-2432-11-11--------1----2--1-1--1-3-1-------1-------111-22122112G2331-631-11133544G3C62-4336- * c.53 Resolvase-like
[ 307] --111-1111111111----1--11222-111----1122222--111-2----1211-11121--11 3422432333323243333-33222434333133334335233243344333333433223342332434333332223223422234444535332--34434354242222222222222243433333443355555--14434545543444334334453543333333333333433342366354455758577567755654557576654567564444445644444444444444454454633344455444444444334434545554444544444444444444544544444444533444333479555444555444465665555555344455587666356456667443344333333333222222223733333233333222-22122222333333333333322332323224333323233333333233223342211111121222222222222222333333333244443222222422222244222232224223344444255333334334454445644344454444444254355554575545868796755655545441121211111212111111131112114444434343444444555444544445544-3333412-43444454444444444344-444444444444444444444444444444444444444444444444444424444444444443343232233333444233334344222233353344334222434444344453333444454353443434444444444444444434334444444322344223322222222231----1---1--11----1111-11125321545553345 11----2-1-1-233232-222231322222222323233133222322331311113333333233121333-333-233444232222423346434322-453-44-64321333123331532418U3-43322113--321321432-31422124-14211222I31311112G1223251522141497662 * c.98 MurF and HprK N-domain-like
[ 308] ---------------1------------------1--------1-----------------------1 122-1----------------------------111------1-----------------11----1--2--------------1---1111-------1---1-1-12--------------------1--11-111111112-4113--2--11-1------121131----------------------------1----------------------------------------------------------------------------------------------------------------------------11--11113-11---1----------1--1---------2-----------13333-----2222322111111------------22122122111-211211111111112331111111133--------122222221111111111---111-1-------2121-4334122222222212333323324222222222222311232212111111112222112222232222---32321113-1--1---------22212222221113211122222122222222212-2111----122---1-11111-111111111111--11212------111111-1111111-11-111111111111111111111111462111111111111111111111111--111111111111---1-----23321--11111111111111---22222111112-11111223111113222-----1----111211111211111111111111----112-111111-----------------------1------1------------------1 7555869-RB71C9JCB99E959B9CD8AAEBCDCC99C79AA78A9B9EACBB9CABA697737464-4956458A389744664865998BB8E68579969EC14f3QTVRTaXIJIHKPMbWKZK**Z1dPkGEHJU9NTFJMGHDSHGYHVMLGANHGDC89NJEYBMGA2HGD*7C8IFhMTiEhKBD8CCDF * a.159 Another 3-helical bundle
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e.10 Prokaryotic type I DNA topoisomerase
[ 310] --------------------1--------1--------------------121--------------- 1352A22222222232224-232223222222433323523856-2644211---211--653269778H-3---1--22212----111---------15111431-----------------211211111-211131---E112331151-11------7111SURC------------411-----53A222222222222232GT985D2226682Q3211111166111111111111111111111-1-34--11111--26--1---321--------------------------------------------384J865659546A5B2764111A59--4115277442C71429A83111---63464344368GCDA769A9A97778788877A-CBAA9BBDCD61AB9BCBCDDBEEAB744897A878668-------------344------------21--22121-22-----142211232241112212333322-15333141122111----35135543121--13111-32-------32-241424-3-2--11----12214121112127941----------1------------17--342262213-33334334444433444344--3221-------33254333223333323-2332222222232333332242233232322222222222222322342232-233333333333--3211111----32822---11-------1--22223333575444542335222223332---------152333333324123526676B222----1131-------------------------------------------------------2 ----33------11111212121111322222211111-11-122221111211-12--111121-1---2211-2111-1122-2-----111--111--------121cNQHQHQIGFGJEHURBPGS*N-OIbFFEFOFDIFAJKEAJEAQFEBEV6DIJ2582456645K12135654112642G163------- * a.20 PGBD-like
[ 311] ------------------1-------------1----------------------------------- ----------------------------------------------------------------------------------------------------1---1------------------1----1----------------------------------1--------------------------------------------1-----------1----------------------------------------------------------------------------------------------------------------------------------1-------1--------1------------------------------------------------------------------1----------------------------11---11----------------------------------------------------------------------1--1----------------------------1------1----------------------------------------------------------------1-----------------------------------------------1----------------------------------------------------------------------1111-----111---11111----------------------------------------------------------------112-------------------------------------------------------1-111---1 ----UWF-1---D8H355596557778555555545555555555555666665447555454554454477555545555655552227B95C673233346ILX1U1SRxtgyooSVU*VpX**R*U**m7*k*SRXksQXdeMWVPOmkN*VZRaVAGOHFHDBYEHVAIKB------------1-4----4444- * a.117 Ras GEF
[ 312] 11-1-------------1-----1--------------------1111----2-1------------- 144-4------11147787-7133D59989975444324415-612-11-1-2211-1--422-9156661-----------3----------111----2---21-1-------------------------3-11112---3-12141121111---1--1-1-2231------------12-22--1--2333346432556546-433116461113223211-1-21-11111111111111111----1-------122111-1--1---11-------1---------------------------11---111--11---------------------------------1-------------2224113-----317452135243322212121222-34122323323173323327624656121-12424411311111111134-3-11---11-----11--------------1--111222132232446435111155232312247333854-2112242--434352-41--1-1--------1-2----2---11----221-1122212-1-1--4521-------------------------11--12--2132-1111112-111111--112---1---------21-2-3-1112122121-11111111111--11111-23321111-1--------------3---1111--211111111111---------1111-13-1---------------1121111----1241316424121211--1----1------11-----1---122-1-12-11--------33--11------------------------------------111-1------1-- 2287mw21OB64444CFNAPJLNXiZYCCAECEIJAED9DCCCCBDGLEWNQZdAFMLACDC528425133345473523346577346EMBF7EC68759549992AFCTJLGKILC9ACBEBPFDIBl*F-IFK9B9BFCEG96D89AG75LCHGBF9CC7E897KACO9ACD2732I43537E5C9N8I79KFEB7 * d.86 eIF4e-like
[ 313] 445443544444444445555557844754563-3334544443535732343244444444444--- 3333355666632655555-5533555555555555555533442334322-3434-3--33236453333-------2335422344111-----1---313324311---------------3333333334364474---3644344432333333333322333331111111111113333311-413555555453555555333325564232311333333355233333333333333333345-1-12-3---331321--11------111111111111111111111111111111111111111111146A64555555525244112444212446-254666588267744143113336334-11-1447447484434444444444444-8787997A854-5443334343635335364455556654444444443324554-----------------------------33333145555556565444445544444444544555434444444444444444442333332232222---553-576A575868555-5354538585555556644333333333-3222222254434335534323-3-25444434544445455465---1534------44443444444444444-4444444444444444444545442324444444444444444433344442-733343333444---2-----111132232212222222222222222222322332555645523443422221-1-1111-4444444454454442333334445----2232331111------------------------------------14411151113311 ----332-1---2333333445374944313333334333333333253345342435444411-111111-111122131212121--35333452111314554-3226475732332231476374CR626693433744533333373274533532G35453422649342432E1214554863443365641 * c.57 Molybdenum cofactor biosynthesis proteins
[ 314] -------------------------51-1---311--1-----2-----1--11-------1------ -14-2--1----2-11111-1---2-1111121111--11---21-11-2--22121111----3--212--111---1111-11211421--2--1--3C12-733--1111111111----221111--111132212---2-112222-1-22-----1-3-1-12----2-----2--1-1--21--------------------13324------7-133111119112222222222222112212121-11--311111111---121---111111111211112111111212212222112212212122222311B141452187234431111322-2131-1231111-1--21111-63123----611A-34233-11-------1-1----1---2--5-3-4-1-55D-4-2----33---2333-32111--------3333111---1--111---2111111111111-2-12-1--2-27329WEGNKHaEEEEGCBKSRQQ7SQIDD8F6-182P51P--B231I1-121324G7--24--1112269211-1--41-31853314-44172-11-7x3312----2----12222222211-11--8681A5211-513233232111213-12142-1292321-1113I3E4761EBB1DAED9-F71F38A79FEFC33253A885EBffD3C557838776777559352546A4-3GGGLGGAELJL--2-1111112112-589111162111112251668655811186MOFKPCOA8CB88-GCC111111111266928B88B755332145444RUX22221111221111----1--111111121-1-1111-11111--1---1--1--12111-4-3 32231-2-2111111-1264436445121433413134243552-13227412A322353231-1-1--4112114111112134121341512621-12441-14-4-142733411524214661727M31834-23-213652224221123312623437171513133B6-21151222246A72322213253 * b.106 Phage tail proteins
[ 315] 22-31-2222332322-322222232122343333333343333322344333234412113112-44 2332322322322223322-22222522222222222265233223311222212222--222323422222222222-221422222332222---111414432532--------------122333322323333432224242232222222332223222434322322222322223333322222222222222222222222222222222222122222223312222222222222223322------11--1---------111212-------222------------------------223222122-24-22111111121232221---3122-2322243222321232222--2124322311112523334232222222222222222-22422623242134442244324332642435323323422222222222224221111111111-2111111112111111112226227B8565666655333355663333-365876882266535354634366443222254243333323253222322232222222-434344333333325233222223223-1211111112223222222554538443355434343343443433-1-4422-11--143433344444444444-4434443445444334436343333435454555565555445332244442-333333333333111411111111124343111213-1111222244455444445266664555444545544212122121332333333343333444444444433442221442222-------------------1-----------------12-12-2222231 11--244-512132566648976DBC64555446555767666565557887C755686455755454445564554146656645454485655E556646467A-5779AGAD7A45546579A4B4N*8287G7546865545675795494A66A68E3623AB33B26643225k22222758G6873364334 * c.83 Aconitase iron-sulfur domain
[ 316] 11131322333333332221122244542444111111111113333324544122232334221322 2432512111111125533-34223533333457577476343343322222343432112242546564223333212323511111332213221--122313121211111111111111111-131211122222211142312111122111111111111111211111111111134533112-1122222222222223221111123211122122332322312232321233322311211232122122232222221222322222222222233222222222222222222222222222222222212222222222212142222222222233221222111221111111132313666544444746553446353444443444445-6766636657536555665786556434434634635434444444455553444222222221122222222221222211123556444643577767653444669766664567677652356543566445564454532364344444443355511213211--1111-222121123446466122333333333423222222222423324333344444254333443334443444441-12324-11-1134223333333333333-33333233333333333334443322343434343433443333333223322223223333222112323222333324434222222222311112333232333352445434463444444342222222222222333343333344365555444222221211133332222222221211111-111111111111111111112111111112342 2211446-943123444473333333333332343233333333433454574533444443444122242242422132244355132354455A54444444441374C7997657655362BB475Lj7-96F3543735864374454563755555757544323742832532O32344G5254464744647 * c.18 Uracil-DNA glycosylase-like
[ 317] 11-11-11111111211321111112111311-111121111132222--111111----1111--12 1221323322223111111-1211121111112111123111122431211-212222--1115212444212222221-3112231134531211---1211111231211111111111111111122121312224311221332-1131111------11-2222--1-----1-1--2123376-42677777577577766795666867623324257676665532232332332222132223453265263349666573321133442221111211111111111111111111111111122222222232-4E6665666453661112125123-2112221222131323213-12124111111111112211112412112121211112-111113111321333635345565251112111111121--------1---13221111112111111111111111221111111111-211113332312111111121111-323212111111223112221211222----11---1---21113211111------111-232111131222212-111111222221-1-------1111211226111111111111112311111121111---2212------45113534776454544-554656445565655455498932233353334333333333362335554--322122211222--11111121111112--111111111111111222222112112----1-1--2111--1-212111111-2114222223434422211111112212--22111158111111111-2----1-1112-1122211111111-22321546551211 3554334-G68323345656544342523533326423443445555336767F5554635524446744335235323333333312226356553434573A55-394EAJB9BEB9D7AB7CJ7Z8z*J2OIU9AD8V79LD9F9AAD88KAFB9A37ABC49C8A4K45858666*66657HEWW3KE5465242 * d.162 LDH C-terminal domain-like
[ 318] -------1----------11111-22222332------1--1-1121211331----1---111--23 2242332333333342244-43224444545232223565333353323433665433223443469454411111113222343222324322221--242634343411111111111111133233533333433223332233433333333343333333333323324343333444333322233322222323223222333333322234323222222224322222222222222122223221232221212222222222222222222222222222222222222222222222222232222222222222222223322222222232323222222223222422222222222223433422222235662343345344444444443-54744546342366654585458753343326333323333333333333326332232222232111111111111111222233343234733777767666666677677766686456545447644344444444473222642222222333345452325242544432434643334333346234333335354724222222243346455437367243543333333333334233532-2342311111143444544444444454-444444444444444444444445684434444444444444344444444334344444544441143222222332133451113331333333334443444333436667476866554356633333333343334333333334433333333333333222233333311111111211----2-111-111---11111111121223222222423 11--232-411122344343434636244132222232222223334433533334443535222222222232222132222222322242423333352442221251C4556365545445533A4IZ4-57E75436446324443454B4945532635423433532544452F2233365683565352227 * c.65 Formyltransferase
[ 319] --1----1------------1----111---11-1---11111--1--1-113--------------- 1-1-2--------111-11-1-1111111111---------312-1------11---1---21-21-221---------------1-111------1--11-2---1------------1-112------1--1-----1---1----321-----------1-22--1--1-----1-----2----------------1---------------1-------1111--------1------------------------------------------------1--------------------------1----------1---111-1-----1-23------1----1-1--11--21----------1--11---1--1-1--221--1------------------------------12-1----11------------------------1----12---11-------111-----------1--1--------111111-------21-31-1--121-1---111-1-----11---1------1---------1--1---2--1-1-1212--1--11--1----24-1------------1--------------1----1----------112-----1--1-2-------------------1----1--------1----------11-11----21--------------1---------------11111111111--1-21111111-------------1------------1----1-1--1----------11----------11---11--1-----------1111-111--13--1122-------------1-1---12-------1---------111---1--1-- H8355AN-*JFCIGS66886966655B778686A767869A449A8686597BC6788AE6D7224451344623451248334544567F96B87FAFBCA2756286G*BHMMIZIFIFGOKcmBSK**PDhNyGIEGMHHRDALBFDZGEiIVDFOT**SNLGINGN*ADYP2FMD*42233EA7779C3ANTOPK * e.35 Membrane penetration protein mu1
[ 320] -------------------------------2-1---------1------11---------------- --1------------1-----------------------------1------------------1---1-------------------------------1-----21-----------11112-------------------------11------------1--1-------------------------1444443261534353----32544---3-1--------3-----------------------------1--------111--11----------------------------1-------1----111-------------1-1-111-111------------1-------------1-------------------1-----1111111111-1-----1----1--1-----1-----------1----1-------------------------------------------------------------1----111---1--11--------1---------------------------------------------------------------------1----------------------------------------1---------------1----------------1---------------------------------------------------------------------------------------------1------------------------------11113-21111121-------------1-----------1-----------------1--------------------------------------------------------- 2-----7-----33733335454756544333334533333333323335456433334433333232-42232422-3223333322245435454444464676--2-*******dacWbnb*qY*f***-*m*NeVd*Yl*oMjaVMpQK*clcgf6AAF*I*25114--92-1--1---2--2213-----238- * b.22 TNF-like
[ 321] -------11121111-1--1----1-----1----11--------1------1-21122211----2- --1-2--1111-------------1------11------1-11---------------------1-1-1--1--------1------------2112--11---511---------1111111-1--1-----1--11-----1-1-11--1----2-------1-321---1--------------------11111-----11-13-1---1--2---1-1----1----1-----------------------12--2----11-1----1-----------1-----------------------------1-1----21--------212-1--11----111---122-1-1-1--1----72-1---2-------------------------1------1--------11---------1-----------------------------------1-1---------2------1-11--1---1-------------------------------------------------11-------1---------1-1---1---131211--1---------------------111-1------1-1---------------1--12---1--3331------------11--11------------811--------------------------------1---111----------------1----------11----1-------1---------2-1-----1-----------2223221-----1121--111----1--2-----------211-----211----1111111111-1--1---11----------1------------------1-------------1-211---- 2456DBA-K8A576D63755647D997658677857573625344368755C67573466694459543464657652665443875564753C4E66475E4CBE49MNoaipvdjPKJLOQN*mJmJ**VBxU*JLQKfNNaMJPOLJjLInOfPQW8OOPOKJCRGCZCEIA6496eA5676INKi5YB987NGEF * a.207 Formin homology 2 domain (FH2 domain)
[ 322] 112-11111111111111121332233313211--322212131164854E81-2222342111---1 ----3A77BBED6A1-1----1---3----------4E46-41456547A72A624482256-8I954AV6--------1222-----32221222----11111122-----------111--13122111223144231138-6-2222-11--------42-1561-------------3442222-169FFHFHDEF8GEGGGEBBCBBBGGG577C866444444JI5AAAAAAABAAAAAA755775-1----2---43-1--2-----2224443333122444444444443333333333333322222222233B56AAAA9BA5C73522286745131621-2EC2--31222322215241-211233133221--236654744444444444C-32122333422-9BB9673697757312124K959832-22222222-332--53------------------------------11112333234555754555544335555456331112--1111221181412211111-1622222222--1111-6722212323111----1---34111141341253-33332-1-1111111211--22695261112211244121421141234422---1121------I6994B9799C7BBC75-8795B9C5A78DA777775BBCEE9977577777777777777C66A77783-BBCBBBBABBBB--3-----------1B8G555575--1222--52233211-465146244635745221466---------1988799999C8D6611---------------111------------5-2----------------------99B1221122222-121 --------2--1----1------------------1-------------1--------1----------------------111-1----3-1----------1-1--------1---11-1--21-1--1--11-1-1-1--111-1--21-1--1------1--1----------------1-1113---------- * f.22 ABC transporter involved in vitamin B12 uptake, BtuC
[ 323] ------------------------2--1-1-1------------------------------------ 112-111111111111111-11111211111111111111111111111111111111111111111111111111111111------11111111----1-11211111111111111111111-1-11---1111111111111111111--111------111--111-11111-1111111----111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111-1-----1-1121111111111-11112111111111111111--1-1-11-11111111111111111111111111111-1111111121-121111111111111--1121111111111111111-11-1---111--11111111-1111111-111-------1-111111111211111111111111111111111111111111--111---1111211111111111--11111111------1----11111111111111111-------------------------1111-11111111111112-111111111111---1--1------11111111111111111-1111111111111111111111111111111111111111111111111111-111121111121--1111111-1-1111--1111111111111111111111111111111111111111111111111-111-1111111111111111111111111111--11111111-----------------1---1-----1-1--1-------------1--- 3334DBD-G7535564555555554655555565555555455555655555575555555545554535565456636655555566636455455555454CAB2FR8HkXXjbQJLMFJNLrpKgP**eBqQ*EKJIZJNYKAMJIGTIBjKNLKOBEMFAAG6HDBG89EB3667l77666IGGJ5NB99A999D * g.45 ArfGap/RecO-like zinc finger
[ 324] 111-11211111111112111111211112112-13333333313123-2331-11111111112--- 2432222122222222211-11112311111211113273122323122222332223222222323253112111112121232312222312--31123222223221111111111111122111112213232222111226533334334412121235332442211122222122121113223222222232222323222111122232333222333333322222222222222221111132222222323223343222222222222222222222223222222222222222222222322233322223322222222222133222232111333332234322333--12222223222112215623462243222322222222222-4442463442223224232222343221132232333221111111122232332112221111122211212122122111111222222322243323323233334446443424533542244322222232333234222221222222224422323322232223222231332234422224353222222222221111111111122255443222332242322223222222222232212222222122233443333333333333-3333333333333333333433333343333333333333333433333333233333333333322222222223333232322222222222222211111111119233333333433445332222223222233444444445444342222222222222232443333122111111-21-1-2-212421122222112211113222333433224 34--982-E332444566332548B9632244464362232233226636663934B324222234334243242341332334422242436247423223266C14C445A566743345548E1B3R*9-A7G6323635442362333272525446756446B3474A446AEA*64698TKXP5IFA9CCCB8 * c.49 Pyruvate kinase C-terminal domain-like
[ 325] ------------------------11131111111-------12211211212--------111--11 2221211111111111111-11111111111111112142143611111111211121111111114212111111111121111111221111111111111111112111111111111111111111111212222211121333333333332223223332545322222222222211111111111222221221211111211111122111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221321111111211118822221121112211112223111122111141131113111111111211111111111111111111111122111111211111211111111111111111111111111111111121122222222222222122222222222222113121222222222222222222322222222342222222233232243232232322222222322221112231211111111112111111112119989B512111111111111111111111111122232111312222222232222222222223111212222222224222213333323232-33443223223233333332222322232323233333232222332223311222222222222111211111111121212222222222222222222321322222222233432222223331111111111332322222222222112121111111122211111112222222221111111-111111111111111111111111111111111 3333A561KA8344555336566656555455666655555455555555555747566556776666569976CDB69B8666667765A6575E8665544ABG37DMBFKHDEC999B697JF7O9o*D1FDN7696J7AC99A678A76N8A8AC7DJ6DAA9P6-759665797*56587OORY5KE58BCFG7 * b.130 Heat shock protein 70kD (HSP70), peptide-binding domain
[ 326] 54526A4ABECCB89552554668E67FGHAF212352472733333423754242539232224-22 52A-42-24224--123DF-F1----DDBEG-2---1349254422-1-3442--2-1----442-23521-211562-2442-141-2121-2------2-21-1221-------1------1227989-1A26---331--3-AAD3B9923344232438D2T8DK44553322424321221-11-1113333343233233331111-1223443-132-1112112-11-1--1--111---22-11-1-12------1--11-21231-1-111---1--1221421112111-----11------121-121113212-222222212-1321-1----1-1-22131372811523333212---1B883-B61D2274B9484C45F33233233238-85789DAA888-888579BEHF7B3G1153494454-1-323333335792124A--------------44-15-----------1733--3414855758433226634644445966347A--58425453885314--821-1-223--11-B13A23134426852656452536843E484222343--111111111121434443441--12112765-221221358623242232621432---93-D------55B93A46BA56655B62B66BB77AACC776666657A979DR87589A786968B8AA88887B77731566656546743--A11211-211-12332333132342324542314311-11-7225527668763442882-----1---1644475875232534222335-216242--5-4454LL--------6--------------1------11----1-1---1----1-- 5-----------2---1---------1---111-----1--1----FB--1-----13-------1---------------------1-21-1---2--3--1--1----2-1--1----11------------------------------1--------1-1--1-----1211--14----12--3-----11-21 * a.43 Ribbon-helix-helix
[ 327] 11-1111111111111-1111111311331321111112211126232123232-1-111-1----11 1532F33766523444444-483358444445A888EAED29397H764344DB834622BBA284C8B8221113111-11422222654412222--262229BC36222222222222221111111111113892111171822533323333333233333435133233333232322311---123333335652343534232244333232453432222244333333333333333434352131111211132441121322131322221112112222222222211111111111113332222112111332222323233213322222133114211331111311111-1-22413122222222335663335344433333333334-558697665B3255539A69885834242143232234222222222111133311112211111--1111-12---11-21221225222333254453444444446355553564645552256334433545343223242332222222222226541214111211111132312422165687812111111111-123233324411111113333432233324334224222532334242-2553422-22232222322342222222-3222322222323222222533322342222222222242223222222223222222222222233222222234334344433322223333322233445332323244445534444332443223232222234442223233433222323322232222222771244--------1-211111------21---1-1221222221222-2222524 1111112-411-3442333466484753433344334414343444533443665533532224223312322232222222222233447333A4334342445434429534423211112155141EX32A571-2-6-1531122161452233431257452714623633442U43523834A4766956256 * c.71 Dihydrofolate reductase-like
[ 328] -----------------1-------------------------------------------------- -1----------------------------------------------------------------1---------------------------------------------------------------------------1------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21--846-2---667333116224223473324173151313513352255957434215363252521554424573673457522124DB35852245154673-872t**rw*jWXLIXgT**MxX**z7*s*PeQOwVlrbKcUQFpTI*XpaabANENODFLqPYaKOA8-231I3121-267534-2-11222 * d.217 SAND domain-like
[ 329] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 51BK--4-3--------------------------------------------------------------------------------------------------9--***r**pcYUXbqc*vNrR***M*m*TbccySmqiNhRXQzXS*d*msi**iLcKE9PC9ULOFG---1-1-21---------1IHQ*- * g.5 Midkine
[ 330] 11-1-13555555553-212111231122153-1111111111----1111121111-1112211-11 5353541222221286433-3311573333336585A8MO241937221322AB9343--54913494A511111111----6-11--22211111---1333442423---------------11-112111115454411136-211221----------11111121-------1----3332411-51122222242442322243331124215714111111115421111111111111122221-------2---222211---11------------------------------------------------12--1----------1211---------2---1331-1-113212212--2-2E554-1--146IEF2148566555555554554-33C44C47D66-B66A77A98A55A98445993233388--------442-3522-----------------------------31CY4-FC95AFGIGEA68884DDJDA99929KEX9OFD25BB8BBA74DAG4JD452----211111111---3892211-1-1-22111111111111-222237-12--1111111--11111111--11111112311224312333333243432321324---121-------32221212331211135-3515212522315552555556225516463656666656536743144451-144466646666---3-----11111134A---1-------1--44444422123937777664C2678723441111111111122222222223252244444333-------1----11--------------------------------------1--------312 ---1333-421-4226764C885ICE93333553457444444333646AADKJ7786444621312111222131111122223212132373333222215332-2C67463232221124154242CQ6-535232143442112-13-25555265533756543472353323271111244674332365345 * d.177 FAH
[ 331] 22-122111111111111111111111----1-------------1--1111121111111-111-12 123141211111-111133-3211223333322111222223132331211221-211111-423324631----1-1--122212221211-1111--32---4132-222121254477771121-2-21211233341125162241111211111112131243211111111111111-22211-1-1111111111111113112221111332111111113221-222222222222211112111-11111112112211-2-------2221----1------------1111111111111---111----211121111111-1-12111111121-1335-3--122112111111221113222312112213333323343422222222222-331342323441222222222222232423222223122222222221211254111111112121111111111111111111-111221222122222232222223222222232223231-22312311-12-32113311221-----1-21323314312122111112121233335211216524111-12112111--------11313111112212323122222214222223533451--232411-11123122212222222222-23222322222223323322321211233333335333454321222222311111111111111111211111111112622111121111112111---1--2112324444323343323322211111111113112111112322324433334432223113211--22--------3---1-1---------------------111111111122-- 3411752-82222355386367765654456552243333244456635689A833354122131312222222322222233323-13273374A21111-23231BHLxONNEUFCEDDDHEOGCSC**I3RIXKFEFMGEEEEGFFEH9EREGFFQKMDBFF54O99618DM1361722213985D78V45BAED4 * c.50 Macro domain-like
[ 332] ---1-21222223221-2--111132222421112-11---1132-123-1211---112-13311-1 3361342222222223244-43117555555822322243151533112321132211--622-D2895321111-11--------1-1-1---------9273E7A24------------------1-1---2-22222--122121111---------2112-3122--------------1233---1-1-----1------1-11111-2---11141111111113213333333323333322211-----------11----1--1-----11111111111111111111111111111111111221111111----------------1--------1--2----1--1-1--1------243-134521322332311---13---33333333334-21-11116121-3222424-11223-34431623227221111111122232-12------------------------------23332-11113333335666633667777584364644-2445242-222213143444533-211222211-55452212-1131-111-3431122-2445582--5-12-11111113111111111-1311343336323423233352232333324324--212-1------22231312222222222-2222222222222222222223445625343444444444434422222221-221222122212---4-----232211312111121211111-1111111122333577776765434563434---------11333111114121156655655664444----773343---1-11---1------------------------------------5-7 JE66A672YE9A754564275756958231434536346456645565684845434644543343441433433223225443344422226223333233533525GKSCLEEDI8B75A89EK6PCn*H2PGR57B3F48I846937A68LDHDAG5BGJB959946A55K7-328*77643614A425245DAMC * b.61 Streptavidin-like
[ 333] 11111111111111111122111132233443---1------------1111111111211---3-11 244-522222211221122-2211222222212222243322221111111122212111221332244431222133--1121-111334313222--3543475334--------------1111111111212222211131634222111---111-121-23431-1-1-11111-1-111111-1211111111111111112233231113221212111111-1111111111111111112111111121121211111511111121222211-111111111111111121111111112121111111111-111-1-11112122111211131411223-1111111141-111-1--31711111111111213--11111111111111111-1111-111222-122223344222122113322333322--------------11--------------------------------111----------111111111-1111-1-1-12-2--22311---1------1-11--1-11-1111--12-13441-222121222-3231332344444552211111111111-----------1-1--112344224333435322233333323323--12111------11111111112122221-1212122211121221222111113321111111111111111122111121-111111111111---4-----111122411---111-1111-11133333332231311111111111111222----------22242222222222433434433433331---544455--------11-----1--------------------22122222223613 D94686D1M11487B799868677776556667678596886765457889888777688787783443544547343444666767765D798887688457CB819GDKGGDHGGCDA9CE9IFAPCg*H-JDN9D99EDEIE5DCBCEB8FBFECBAE9AAD96E98A78C65GGB*987BEMHLP8TFFC789AD * f.51 Rhomboid-like
[ 334] ----2--------------------------------------------------------------- -----1---------------------------------------------------------------------------------------------------------------------------------------1------------11------1------1--------------------------------------1--------------------------1-11-11---11-11---------------------------------------------------------------------------------------------------------------------------------1------------------------------1----------1---------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------12----------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3*--11C-XEC7ABD22-22111121111122111111112211112112212111211212-1-11--1-----11-12111221---13221211111112112-15AlAHGHFaSMQNTVYfdT*Q**TAhVySSQRgNUWHPUUPLnGK*PaJOMMx*GFG9CEAB*32IG1DFE*212328--22-915GIIHH * a.126 Serum albumin-like
[ 335] -----------------------12------------------------------------------- ------------------------1----------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------11-2------------------------------------------------------------------------------------------------------------------------------------1---1----------------------------------------------------------11-1---------------------------------11----------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------1--------1--1--------------------------------------------1-111--------11---------------------------------------------------------------------------1------------------------------------1----------------1---------------------------------------------------------------------------------1------ 221134718333334575645444545444655444444444444336444454557344455555663554555663575455676664647439567425465224B2eqmm*jqSUSSQYU*yJ*U**h2*T*TQPOkSTYSOXTXRuRL*VtWaYBE*WEKBBYBGaFNVC3787*57444944645555798B8 * a.278 GINS helical bundle-like
[ 336] 11-1-32222222222-1-----2222222221-1331-----22222222221--113-1111-122 11211111111-1111111-1-11111111111111111111111111211111111111111111111111111111-11112111111------1-------2121111111112111111111111111211111211111111111111111111111121112111111111111111111111111111111111111111111221111122121111111111111111111111111112211111111111111111111111111112141111111111111111111111111111111111111111111-2211111111111-221---1-2111111122211211111111111121211111111121111111211211111111111-2212222221111111211111111111111311111111111111112212-12111111111111111111K11111111111131111111122222222221331122221222121231122211211111212111121231111111111122111131113222221111111111211112224211111111111111111111111111---111--111-----11111---1----1--11111-------1---1-1111111111-1111111111111111111--------------------1----1111111--1---------------11111111132221-----------1---22222231221122323322322222111111111111211-11111111111----------111111111111111111111111-----1-1111111-111112111111111111111111- 2--1246-213144332231122322-222211232222212211122223234225342222122--211-121121222222--12123325432232132429-741JUkdbbUMRMMMWR*iKrN**k3wa*NPKRZJRfFLTLVRWJKdLTQNM967FFCC5VB9C7G95212221223275292561212221 * a.137 Non-globular all-alpha subunits of globular proteins
[ 337] 222222222222222322222222--------222-----------1-22123222222222222222 2223334333333333333-33333333333333333334333233332333333333333333333333323332223212223232221222112222112111121111111111122222111111111212222222212323411233333333323232333423122223221232211331122222222222222222222222222222223222222223111111111111111111112----------------1-----11111111111111111111111-1111111111111111111111126211111111121223221222112222113233222323332232122232222211111222222222222222222222222-22222232222222223222322222222222222222222222222233222221111111111222222322223221122112222222222222222222222222222222322333323223322221122312232232232222222222223311122121122221232323232333322312111111111111111121121121223232323333333333333333433333341-2333222222233334333333233333-3323433333333333333333223333333113111333333333333333233333333333312232222233332332233323333433333322222222223233332222222223222233333333133332223233333323434333332231121111111111111111111112---------------------12111111211222 4366657-947487844514445776544343366744544343334444547634444545663543444344533343444345755473475556644865632635E99795886756669B7C6IyC1ADE7867C68A859866A66B667778A57E6767687A7C64589*78856778F3CB87A7761 * d.101 Ribonuclease PH domain 2-like
[ 338] -------------------------------------------------------------------- -----1------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1-------------------------------------------------------11-----------------------------------------2-3---1---1-1---------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------1-------------1---------------------4-------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11------------------------------------------------------------1------------------- 1222--G-1--------------------1-11----------------1-1----------1--------------------------------1------1------C*mnchyfRQQQQWQeaMgP**e2lXwNPSQVNSVQGOPUFSMN*RhRV********3NnZ347*---------------------1--- * d.171 Fibrinogen C-terminal domain-like
[ 339] --1----232523322-11422-51--12-42------11----1-------1----1---1-2---- --2351-2---2-19fQ66-6I--HW66666BIHNI6JWo-b3d1--2----442226--12B135E7735-111----1617-----1--1-11-----2---3--121----------------1--------66687---33------------------1---1-------1--1--11-122---12----------------11-------22433--1-----4--------------------1-2------221--21115----------3-------------------------1-----111---111--22--222222212-13-------1---1----87-1--1-2------1-2--733A-----3-MCE1-9B7AC833442443442-34A33E39856-411112321432964728592224268222222225111-823--1---------------------------67F9-6uaHfGDDFJH5577799GH887868W8UTemd36785748BCO9JAPT567---121-------2-2922-121-----3-----12--3----122121-8---------------------11----2--1114-3--1----2-1----1-11-111--111-------1-2-41-3443333333-2333333333233223221111---121211111111111111122333321---------------1-111111111-2313111------------443242422222556547663424552a3---------1---21111111212114----DGI------2-111111--------1----------------------------2---------1-- ----111---2211375856555A9B8332322632566666655443787DGD66B444334-112-------1------221-1-1-55458553113233545-283926235233433535B263Bd4-7444343723442324232571633B36922362945H1224-13-----1123194421713241 * c.123 CoA-transferase family III (CaiB/BaiF)
[ 340] --1-11-----------------12332-21132--1111111-1-1---21--1311323---1--- 1----111111122------------------1------1------111------11------1-1-------------435-1-1--1131-4--1-------1113-1111111111111111--1-11-------------------------111111---------11111111111---------124454555444545543544124441--33121223211122221222222222113321---------------111----------------1-111111--11-------------------------431-22212224152---411-25-21152-----3--321-11--12--1----1-------1-1----------------------1--1---11---------------121------------------------1-----1-------------------------1-1--1111--------------------------111--------11---2---------333322222-1----122211-2--211111-21--121--1------5524333334332222222-1-11--33123144231-1111--2---12122124----111--------------------------------------------------1-----------------------------------------112111-1-1112333332122222232221111111111-------11-311--2111-212-2212234434444433433-----------------5112211--------11-------1------------------11-11-------1- 31-1-11-5--1--132311---233333223311--------543-1--5848344211323131-1112-11----1--1-121-1-14-2-223111--3----275*ov**hdKJILNOJbWFaN**Q2XLjFIJGdKKVI9JJFESEBYIPPLRm**OtiVQlJSkNJVP---181---1-11-31-4222111 * f.54 SNF-like
[ 341] -------------------------------------------11-8--1313-------------1- 1-2-1--1---------22-23--1122222-3333-111----12------121-------1-1-1-24--------------------81--------1-3721478--------------1----------------111--22432214422----1-22146652------------333----------------------------------------------1-----------------------------------------------------------------1-------------------------1------1------------------------11---------------2-1-111-----12322---11111----------1-11-11-1--21-111121111111---4142-111132-111111111111--1-------------------------------42-2-1------------------1------1---2----11--11111111---1----------------------1------1-------1---121---------------------------------------2-4---1-------------------------------------1----------1--1----1----1-------------------1------1-1---1--------1----------------------------1----------------------222---------1----------------------2-----1-1--1111111111--------11-------1--1---------------------------------------1113 11----T-1---5678BD74453383355654555553232332335578DDCDGG697875543334335334333333332332444FCABIAA98AB78AOFV-9A-zUURZcqMKG8NMMcVOiMk*O8kOoJNKEaJOMMEOLEGQHIdLPVOG42C37T*7*DHH65J-1UMCB8B8WBJUq*7ZHC5223-4 * b.118 FAS1 domain
[ 342] ------------------------1------------------------------------------- ----------------------------------------------------------------1-------------------------------------------------------------------------------------------------1------1-------------------------------------------------------------------------------------------------------------------------------------1---------------------1---------------1111---------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------1------------------------------------------------11----------------------------------------------------1---------1--------------------------------------------------------------------------------------------------11-------1-------------------------------------------------------------------1---------------------------------------------------------------------------- 1111--L-1---11111111111111111221111121111221111112112122211222--1---------------------------1----------1---32-*upo*jZTRSOVYWkkO*W**e2xVzCSRVhTWZXLVVPLXIJvTQQUdi*kd**52612416*d2giI*1217-FLJb1DU-1----- * b.12 Lipase/lipooxygenase domain (PLAT/LH2 domain)
[ 343] -----14232222222-57873334--34646-122211----341321443531---11------42 3341532333332366744-4511744444436555447545542231411134533311446143555451111111121133151211223111----3132554-311111111111111358546366514-----111424334445344433333353335453353533353533443331114234444444444454442243434444323-11-111--332111111111111111112--1--------------------------------------------------------------------2314A333333373814444675334111221577C641-34A1113113144444411111545762225335644444444444244344343463-555444544476564434543434544555555551333373311------11----11--1------111113544333334856887588886688888876889466414446544444444545549464342454345113454-558756896788714351655623353343441-1-11111121111111154156116254444143433333443333434444443---7441--33355441554444444444-442544444444434444457557334555555555555555554444444314444544145552321------1--4644633331311111111144444443444488886897679776766111111111154454444466555221242211111116531442233-11-----11------------1------1------1111111111333- 2121-11-21321-1212322222322--1-421--11211111-121321234414121221-1-1--111----1-----------11311243-12-1-12---1732-11-----1---12-13-4A1111311-11-22-1112-----21122---1211-121---212555V43453B5692644741115 * d.134 Nitrite and sulphite reductase 4Fe-4S domain-like
[ 344] 11-1--1111111121-122222144433353121111111111111211112111--11-111--11 2112453444343354445-4333454444443333445625263333343353333422333445747541222211-13-32222244531411-111434343432-------111----333333353334222231115253543342233333333433245633333333433332222221-334444444643464454225534444333444433334342333333233333333332331------2-1-21----2-112133311121113112222222222211222111111112--333---122-13----------111111112-3-122112443112--222112-1122222221----222213222221133243333332-22222522222-2222222322222222211422222232222222212212123-----------------------------2222222333323333342222322333342442222232222222222222233323233342222222212122313323122232322-132222223322245222122-22222223222422322222225432242223333333333333343433331-12232-1---164453624455455544-4444455455456444446445648634444454445444444544433342-5666665565652212221124443223333333333333342343334323222346766433533234233222222222223445444446545544332333223222322-222222111-1---21------------1---------------11-1-1212533 33-21-3-3-1322235564454976A2222323333756676233663456443433456523432213224333212335543245344454544322244333-18376544AD455566264854BU6-73933444355235613443623326-1437141123511653333U53453979B2D333A6445 * d.161 ADC synthase
[ 345] ---1111111111111121111112--1121221--------112131--1111121---1111--11 7971533233333332244-421152444442222244433446222322323332231133735344453222242311133323227556-4111--352424233211111112121111444254434434222443343336765345343434423422334452222221222132123311211422323343333434335333333332273333222223333333333332233333333323233223233433333443322334332222222222222222222222222222222232442222313112222222213111221111111122111222622121112211131333733622222333353343445533343333334-75766C67442-544776799A56324335353533344333333333222256211111111111111111221111111-11-474323444466665555455553655552446443552233323534367364341342355222223243344314634344287445333454636224527745223223333321111112113232332222342332222322223232322342234--34222------34324343554334433-5333443333533333333444223432312222222222222433533341-233333333333--13111113533345333332221111132224444435222426666466554553543521111221152222333332222234453554442222--62333344111111-111-----1----11--111----1----32223222222732 11--111-843---2121221112321111111221111111211112131434121111111111111111121-1111111112-1-11122221111111111-18614222-42111211551138H7-62D122361221-111-311424325-2-241-2--1-7D413543g22242EAJM1A6212-1-1 * c.129 MCP/YpsA-like
[ 346] ----------1-------------1----11------------11111-111---------111---- 3344433333343343333-333336333333333344664556333342233452343333434336774233333344444333233333333331-4335433342333333334433333333333333334444411144332244332223333333133334333333333333332222333679BCECFEFF7FDEGGD579998EFG665565434443465455554544555545323535434554543422335544344444444424444333333333334311111111111113333334442576B6444444454664765777656245562466454343246665233322544321232233213322211322222222222-1111221212433333222232332133333333333344444444463333344331-1111-1334444443443333323234433433334444444566665555666645445335433433543334434324333232332222222222442234343343333333232333223223244223333333333333333333333343552222222222322322332222222222231-3222212111142224332333223222-3232223233322222222444232224444444544434344422232322232222222222222222222233332222233322232222322234333334342333433333233332333332323323323242222233342343333333433334343333333444343334221111--222122121212212122233233333333544 -------1--------11-----1------1--1--1---------1------1-1--1------------------------1---1----12-------1------1-2----111---------2-131-------------1------------------------1--11111161-2124112-21-11-1-1 * d.175 Penicillin binding protein dimerisation domain
[ 347] --1--1---------1-------1---11-1111111111111---1--1-1-111-1111-11---- -13--------1---------1----------11112-11-------------1-------1----1-------------2--1-------------------1-----1---------------1-------------------5546556444455555555534546444543444543--------------------------------------------------1-------------------1--------------------------------------------------------------------------1111111-1-------------------1-------------------1112-----121-1-222211-11121112113----1-2-1221-11111131112313-12534232111211111111-----411111111111-2222221222222221111-111-11--1-1112111111111121111-11112111--11------21-1----2-11112-------111--1----1----1-----111-2-1--1111--2--------------------------1122-1111111111332213322112211211---1--1--11132332413333333133-3333333333333333333333223213333333333323233333333331-222222222222-1-2-----111121-13111223211111111222222--1-2-3333221-112213-21---------11113-1--12221122------------211--------------------------------------------------------- 12-1766-311166998888899A76999A999A89599989999BA999A888A9999AAA9789A967986A79B6BA9889998787C88A787788477ABK1DA3JIIKLGBDGEGGGBVTCREg*S-UNQ7HAHSCHbHCFB6ECDDICGGDJ757A97CCQHPCBB97A5A6v86568NHFU9A94697456 * f.23 Single transmembrane helix
[ 348] 112-1-------------------111---2-------------11---12-1-1111112------1 -12-12213332312--11-11--1211111-12221364-1-21121-111355331--11--216122-1---21--232-1-1--1112-3111--13213412222222222222222221----1---11-----------112111--11--1------12322-1-----1----122-----1256686756757777774255547754365422------41322222222222222332254-1-11-2111121112211------11111112---1111-11---1111111221111122111222--24155555555656-311544423-74-2---2122-2-3--112--323-133341111131953---2111-----------1-3364383512-232211132111142111--3------121222222-22112-122312111111112111121111112124-224314----C9979B445532258545534533356512445113224213421111111351111111111--3--5-2--1233---2111-1-1-22212311-12332333331-----1---12-1-1-772322331325888956B777676B8697---2---------74445544555454444-5434544454545444445666663326755666666566656444354441-6444544454551111-----343312-232221211222211128888838223424454567826689343222222222214559454437566533444443333333---711111122212111321----1-1-2--------3------------------3-2 -----11-31-11131312133--21-114112-11-2131221--112211222321------2-11---------------1-1--114234132133-12314-173BLUKMGE8967AE8NM4HAO*A-DBO7968CAACA48988973H8BG8E59D4HB32544D87C5-412A---2341132357-HAHI- * f.49 Proton glutamate symport protein
[ 349] ------------------------------------------------1-1----------------- -1-------------------------------111---2---------11-------------1-----------------------------------2---A---1-----------------1-----------1---1--------1-----------------------------------2-------------------------------------------1----------------------------------------------------------------------------------------------1----------1--------------------------------------221---------------------------------------------------------33-------1----------------1----------------------------------1----------------------1--1---------------------2--------------------1------1------------------------321----------------------------1----2----3------------------------------------2------------------------------------------------------------------644444444445---------------2----------------------------4-------------1--------------2141222-----------------------------------------------------------------------------1-- 1--2473-21-------1--------211-1-111-1-1----233--1221-211211----11----1-1------------1-1--11---12-----1-1-2-2A8D*****qYPQWcnT*oU*R**q1wa*ZZca*eevUUkTOLpUS*Z*QX*32--142171161321---1-111---C5b-FH1-12321 * b.11 gamma-Crystallin-like
[ 350] 22222211---1--11221111122222222211222-22222112122-22234332222-111-22 2121111111121211111-111111111111221212231-1-11112111111111--111211211211111111----1-1---112111111--151111-111--------------21----11--1----42---1111----1-2--2111111--1-1-212-----2------------111222222221222222112213231111-11133312223---------------11-11111221221111111111-111121211111111221111111111111111111111111111111111-3111--------------1-----21-1--213211211--1112-1122--1111-1--1112122121221311111111111-11111111111-11121213321121132---111112-111111112----12211------11----1---------------22211-1---11111111111111111111111-1111--111-----------11-1--21-222222211---1--22112213-11111111232-13223-1222212-111112-2-----1111-2111----21-122------1111--11-212111-1--21--------1-----------------------------------1-1---1----------------1---111-1--111-1111--1--2111111-22--1-1-1111-1---111-------------1-----2141212121423---------21212-----2121-334-3-1---------1111--111111-11------------1-1-1------1-1---211-2-1---111- 1122375-E46234152455344644222144433423231222113723454314234655243335233255323333377455331464266313137633763AJ7*QLSSTOEBCBFEGVSGeG**W7bNeBIIGIDHOG9CBDAJHFQFOLGG6AGCBGFABBBU97A64C65*734CBQcM*5VM548627B * e.28 Reovirus inner layer core protein p3
[ 351] ----1-------------11111-2----12-------------1-21-3411----12-----2-5- -1--1------1---------1--1--------------------11-----1-1--1------1111-11----111--1----1-1--1---------------211--------------2---1-1------11--111---121---1111---------22121---------------11111--1-------------1---11-----1---2-------1---11111111111111--------------1-1--------------1--1-------------------------------11---1-1-21----------2-1-111----224--2---1111----11---1---11-------1-------1---1--1-----------------------------1--121111-1-1-------------------11--1------------1---------------------1----------------------------1--1-1-------------2----1-------11----------1--1------------------1----1-2A-----------1----1--------------1-------------------1---1------------------1-------------------------------------1------------1--------------------------------------------1------------------1--1-1--1-1-----21-------1--------------1-11111--2-------------------------------------------------------1------------1------- ----1---3--1311-1-23--3-1--1111--122112112243312-13233-113--1-211-2-22-1-232---211--1--1--1-113---21-1---1-16HKZgfRi*XTWbbpc*wZ*U**k-xe*QdVUsWV*eYYdQWkXN*SZVVSA85H8AChiRgFFK44145-5--1314B4F1F11312111 * e.1 Serpins
[ 352] --------------------------------------11111------------------------- 1111411111121245422-22116422222422223222142311111111122111114411834438211111111111111111222222221-1211121121111111111111111111111111111222221114112112211111111111111211211111111111111111121112222222222222222222221222211112111111111211111111111111111111122311312222222111221111111111111111111111111111111111111111111111111111122111111121212221222111221221122111111111112122111111111111111131111211111111111111-11111111111112212211121112111111111111111111111111111111111111111111111111111111111111111111111222222333332222443332222212111113113112111211111111211111111112111211121122111111111111111111123111111111111111111111111111111112122111111111222111121221221-1111111111122321212122222122-22322222222222222222221113122222222222222222222112211111111111111111111111111112211111111111111111111111111132222222322222213221111111111111211111112111111111111111111111111112221211111111112-122111111112111111111111212321211 33--317-722-534136352223-4322343322-2--22-22-2434336552-343323E333442335422232344443341123523F8Z64432241121CA2KQTLSLPFEGCEHDaR8a8j*J5UPeFDCAICEN8CJC99HFCVCNIKF5AP7B7A6L9DC8L66-443I22342R37G584416CNF3 * d.100 MbtH/L9 domain-like
[ 353] -----------------1111--1222223221111111111311111111111-----------122 1121333444422222222-2211222222223222425413333233222322232222232253562522111211221122222222231212-112232432334----------11-1122222223222233331114242222221122222222222212212222222222222222221-3245555555545555553344445553352322333333322333332333333333323311-11112-1-11--11-2-1112222222333211322223222232222222222222211222111123234111122222221224222112-22112233211111222112-11222333411111334333233343233343333226-44544534363-6445454354653325345565664452222222222213135-----111--111111111111111-1--23222345554555456733334453444434534433322335332222335623323323222222222333345225333432353332122232222443423232333322222322222222222222222243232232222222223222232332331114333------22442222222222222-2222222222222222222222443432222222222222222222222222-22322232322222-2111112222333322221321222222223332332222232222223222222222222212222231222222223222232322222222212332-222222----------1-------------------------12121111112223 111-223-85433335687755669753433343435443533333456997E97644435442224243322233313423343322336563553234435559-5C324422542242232A52728a4-55A2242544312421141292314436133343122A33314563X33464G9CCAE97872634 * e.17 D-aminoacid aminotransferase-like PLP-dependent enzymes
[ 354] 113-2121212233152----111211121231111111111121212--1---22211221----62 4521441111211111112-1211211121211315344314222112132133212111134321135412111211124152-2--3447-3111--113222111211111111121111111111211111455341-252G356334211211122142117A53-1-----2--1-56433222722222222522233223232222222322222263343363333333333333333222228222222262222333222211133322321312112222232323232222233152122111111111273243333444334533333211462213A42433313421132521-12238115112153494D9A8532222222222222B-4A747C36D861688EC6698A664G141956B88B452333333332533184111-11111111111111121111114-5615BB4333127657676E4444BB894544575F7486A1297C2A5988C55653A81122111222231332714147323132123331122511313665431-3111111111112211211111111133333142111211245521121211411111--24223------32-13632563233951-413551211243144244185731123221122113259331552332-13--255515435611---133313242253412----1-12--1-2111123212111113455332A21122143111111111115245222223424353527343333223--G14444D522232222311-1------------------------1--------2221 ----231---2123-1-2--23-1-----------11------1---111--1-----1111111111112111112122111111111-----1-111111-112---23555A273222243A6272CN3294631226153745311422522235112--261314---42-221-1111121-71321-1333- * d.268 ParB/Sulfiredoxin
[ 355] ----------------------------------------------------------1--------- 359--------------------------------------211-------------1----------------------11--11-39BC9-C23---3623191A68--------------43443424343312243-----544244411223236431211CAE1131232222222-------22-11111122111112211-2211121111--1-------31-1111111111111112212------------------2-1---------------------------------------1---------31245---1-1----1-661--2-1--1--23-4414221-12--14---96L933621111A9CD9A33B886644544455557-4965797D264-94459B2B9C26763324164-423245555555538963B771111111111----11-2-------1-11312C-466336ADDCC69677788A986673CFBC887E-245642332A432524554546841111-1153476632643-42545334152133366459685755A-21211111-33222222243126AB3346569-725377773785676647A6781--4115------869C6567668778787-86767887868877777775C76B3644555455555545454956457752-633455534555--1144232677842659112221112111112676665423162AA8BF9EB5BDDE846655442442546A786444448A78BD897985552322--G-11--11--------2-------------------------------------AD6- ----------------1-------------------------------------------------1------1------------------1-----------------2---1------------1--1----------------------------11-12--1------21-------------7-----7---- * f.46 HlyD-like secretion proteins
[ 356] 22323343444444336334433143331432112222222222322222232233333231112-11 34824---------24311-121143111112243543711412222-111-224---11-153413443-1111-111-1-2222221133-1-----12-222-2-2---------------111121112112223311122-12-222--1111112221-12113-2-----211--1213322-322224242332353335334433333122131122222216--------------------2-1-12-1---33114511112----2311111-11322333222221111111111111111---111151-14111111111123--113-412--111111221112123111521-1133112-----3188A-112133-22222221224-21522425-75-7223447544774224145231345122222222264313122--------11--2-111222211211-11-1251-22224567875344435588454434B385475-3553212--3-6467112-224---------11-131-112-111222111-1111222111111232111111-1---1111111111211-2223132122-33-1---1-1-1112--1-1-2----1-2------63441356446666566-46465666564775555559A7452116466666667656565545444554-355555546666-------------2222622221311312333211-11-3---4244444665137411464-11111111-1--1111211111211313111121111--11331111--------2--------1--11--111--1111---2122233333-61- ----321-36-11226796633486544566563333333333333543449D612513222233323131141222111233343225--472221121422324-193E88979B5563686LK5G5XxG1IAH5674B577646756865D6765735135354839669741-21-1111431168551321216 * c.74 AraD/HMP-PK domain-like
[ 357] ---1-111-------------1-21--2121-1111121121122232122221-1-----222--11 2322222222222222222-2222222222222222222233223222222222222222322222222222222222212122222244542422-111312112111---------------2224322332222233444224232222222222322223222234222222222222332332233333333334333343333333333333333433333333432222222222222222222233-222322322222223222222222222222222222222222221222222222212222222222244233111222132354333333414113223244253233433334222223323222222222222222222233333333333-22222222322233333333333322322232222222322222222422222232222222222---------------222222222144444333333333333333333333334333324333222334324222432222222222222222222342322232232222222332222443422342322222222212111111122322223333332233322222223222222222222-1222222122233333333333333333-3333333333333333333333333334333433433343432333333333233333333333322223333322222233322222322222222322222222222322222322322222222222222222233333333333333442222222222222232333333111-1---1-1-------------------------22422343332332 11--323-41213333332454434333333433334333333344333344443333333333333333334334424433334434337333373343331555-3B1A475354445334454352Da5-5553323314542443344333942434735424434C33733343f3223243783433574444 * c.24 Methylglyoxal synthase-like
[ 358] 11232222222222222122322222222222233221111112222233333122222122323211 4442634444432455656-552255555555555555553635965645456655452254645466664111111111224111111142121111112121312231111111111111121111112121122122222223232332322222222322222222222322222322222221112222222222222222223222222222222222222222332222222222222222222222222222322222222222222233222222222222222222222222222222222222222222221121111111111112211211131212221424423333233221111241322222222222222322222222222222221212222222222222222222222222222222222222222222222222222122222122221111212222222122122222223222222222222222222222222322232222222222223322222222222222222212222222232221212223222222233332222244443221111111111111111111111111133222223222332222222222222222222212222211111133223333333333333-23333333333333333323334322232333333333333323333333321222222222222111211111222222322222222222222222122222222222222222222222232222222222222322222222122223233333222333322221112111111111111222222-222222222222222222221111111111323 1111112-5223224333433332322223243333133333333333333433333334323342221421323431332334333334633342423332253612A175443324375444AE295Df6-56I235745574153515345255261-213322211222223564i33345E54A3742411113 * a.156 S13-like H2TH domain
[ 359] -------1-111111--------1---1----121---11111111111--1--------------22 1221411-----2-2----------3-------1111211-21122111221342123--2411112323-2222222---11-------1--1------1--1111-2-------1------121-11------11121----11-111-1--11--21--11-3112-----------1-431----1--3222222321223222112211222121112122232211111111111111111111133231221111166113344422155433331123113333333333323223222322323331113333---311111111212---1222211-11---1-21-1----2-211--2-2-2111----1-312113111-2--11111111111-1221231122--122-2212322311-1-11122221-1111111111331------1--111----------------------1-32--11-12222221222222322222222231112--331-----1-1-2--1--12-2---------------1-1---1-11111-1-11-----111122-1-1----------1------------112221--1--11-111---1111111121-1--1----1--11132121322222222242-2222232222223222223655123212222222222222212222222231-311111111111------------------332212123131--1111111----2-22222332-22221113111111111-222312222333331111111---1111--1111221111111111--1----1-1-1111111112121-----------1--12-- 22--534-C53-333AA97665985A72242223222222222221CB7C576855611212331222125214155234111111--1843A23811126C633314C2IEMEJIFBA8ACEDLICOGi*G-MHN7CEBF9EDE8EAD9EB5ECGAGJ546FNIABG98O8DC2133-212-A7RZ**7hK42UNba4 * f.19 Aquaporin-like
[ 360] ---------------1--------------1------------------------------------- 566-111111111111111-12112211111111111111231212211111111111111111122223112221112133143433232223323--333242135222222222222222244333432433222231212223412221111111111111143331111111111115224411412244444444244445422443354322315323333333212222222222222222222221133122232211331122221322222222222233223223223333333333333222222222235223222222222244111332422223452125122324423333112353333343334343533333433344444444443-22333323434333333333333333343533434444333333333333433333333333333333444335333334333313353334444444453433333345333333435444454444544544333343344443344433333434344475433444444444566636543556694443343333332334333333333334233342443333333333334333333333332-3333431-33344333333443332333-433333333343333333333333333333333333333333333333333313333333333331133333333333334333333333333333333333333333443333434334444343333333333334333333333433333334333333333224312222222112212221111-1-2111-2111111111-11123322333233142 21-1-1--11211--212121-111--11111112--1---1--1131331-2131-1-1--1--1-1131-2-111-----21----2--11-1-3--2--1--1-1-191532--112124274154DQ81528-542723221124-31133623311-2613-4--226-32-22A222-152773311113-31 * a.223 Triger factor/SurA peptide-binding domain-like
[ 361] -------------------1-----------------------1---2-1111-------------11 4372F33333322243333-3333333333333333344425431112121134332311A713426A53111111111111111111111122112--16132A3426111111111111111331351111111113311131422222222222112222237236211222222222211111223-2333333535935355314223133721153121111116323333333333333313311211111111113511111111111111112131233222222222221111111111111111111111131156333353312142661111214311221133611311112214111213211111111533131113711113333133331-3353433332115335331313313424121311111321111111113113212111121111111111111111111111111112111111223343336777335377753A435413211125313313111451111211311111111113113-4411113321111133311151322-255111231111111111111111111111113521232112233333533333333333331-1111111111162665435667577555-655566555565545555634444344666666656656566545555555114333333333331111333332222247272222222222-2222656862411142332322222222222432222222221111333333313332212222332222211111111111111111111112111-1111111---11111111111111212221311 111233--211-4362233644486745354233445555555444334434433342333344444434414333535544434444325226552446164542-47244222322322243853324H3-33521233233343132531313233222232-3222-4424133453323546483761176653 * d.150 4'-phosphopantetheinyl transferase
[ 362] -------------------------------------------------------------------- -----22-224-2------------------------------------111-22--------3-----2-2---222----------------------------------------------------------------------------------------------------------------16C6969A68AC96666AMCKKMG8766861847NQSTOR8428887887888888863345H6--EK--8-7HI--CN-264333424669979878B99979B7A58666666666666658822-888B-5-BYCCCEAAEAA8-k--2222-2-2-9-3-----2--2---GFB--11-----------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------21-----------------------------------------6585-723116366652-1333466531161333333787AB222747657787874846663213333--611111111111---------------------411-1111-111---------------------------------------132----------------------------1-----------------------------------3-------------------- ----------1-121--------------------11---------1------4---------------------1---1-11-------1-------------------21-22119I993kHpWAvL**v3YSfEHA9d9F*V9PKA8NA22---2111---1-----2--1------------111-3-------- * a.142 PTS-regulatory domain, PRD
[ 363] ------112112121--------1111211214121111111111131112121111--1------11 3333433233332354555-555566666665555576B93444325221122222221144524333444111111112222222321111121111-212245212211111111111111223221122-22444331113244422232233222223322255331121321111122222323124244444434253444323333335233323222223222222222222222222222222222322322222222222222222222222222222222232222222222222222222222333222212223222222222222221322222122114132332222223321-1121-111211111222223121112122222222222-11111111222132252342323211111211111112111111111-11-13111111111111111111-111-1111111111122111111-1111-111111131111111221111112111221111131112213111221111111221411-21132232242212212221211332324221111111111112112111112111333322223222223222334222222342321-11111------42232323343333333-333333333333333333333333223333333333333333333333333212222222222221111122111222124122222221111-122232323222221222224223243332223122122222244432222222333111111111111111-323332111111111111--1--2---1-21-----11-1----22222221321211 22221-1-2-3342566878787656744353445634442345449457586935655653244453255663455255566565423486635465345158C913C42555355453143455453BU613381322325454344234374553714242421833255424763K34376C7AA3A43445531 * c.143 CofD-like
[ 364] 22324311111111113332122666674764333775666665576755667554444541123122 222--116331-1-11111-11--11111112111111111111----------------11--1-1---------1-4443434444223213232--22222432221111111111111122223232223222233111224554444433311121233435543-111---1-11-3334333133444444464444644543554644445454444444445444444444444444444544444455454445555554544444445454444444444443444444444444444444454444444435466666666666654665666666463657544343535334563455245111111111111111112111111111111111-11212111211211111121111111111222222223211111111111112111111111111111111111211112111121111111111222222112223323222222222212111111212111222111112111121111111112112156665555665554556556566223221345222222222223433223343235112211413122412222232222222232331-11112------21112111111111111-11111111111111111111111111121111111111111111111111111111111111111--11122112212112111111111111-1111111111111111111112211111111211111111111233344444233331111111111111111322211113333333233333322-331332233321123411133344535551442 2---221-4123-1414341--11111222312-1-11-113321132143222331-244521111111113211131211111132248242231211363221139362222344441131A1261GS3-538332-43443123233338423342451232232431242-1-593321-41-53225523213 * c.107 DHH phosphoesterases
[ 365] 2254543555455366545352285441142242446531254584858497BA57716162336211 5CG33-1-----1-21155-52227155555522221-211333-1-1-111111-----22--241242-1---1--1337-222113334-54311-3452233411--------11-----677558376463446665432-225333122221-1-11333231--1-----11---22333652311111111211112111121111111C8221-1------11-------------------------------------------1-----1-11--1-1111-----------------------------1513544444444438444332232443-322576113126121113234322111211111235432114558711221212212-5656825316414112232523234232332432332224444444434442A4411-1111122-11111111111111----142452111124333242333333343333134533326224343353324433242A53324411111112215562P9D647546534549GCCH9F8E4454AF7I2233122223113111111122115335551122423234554456444444554551-11333--1---54344523554343433-53333333335443333353334322345454444444444545447332421434344434444111211111111142434111131121121221223422322233223234332222233333111111112433433333346652332322334122211362233331111111122--------------------------6526676867-314 2311-13-5123-1-----1---1-1-----------112----------11--1---------1-111-11111------------------------2-11-1---8134221122423--3-22256C1-224312-33---2-321--221323--2-124-1-1111-311312A1-1341--5-19--21214 * b.125 LolA-like prokaryotic lipoproteins and lipoprotein localization factors
[ 366] ------21222222221211111-------------------1--11--1111--------222--11 3421432222221131111-12112211111222223233-22211142221343233113352332B6611111111----------11-1-1--1--1942262444------------------1-1----112211-----111-441-1111111111112111111-1111111-1-11---1-----------------------------------------2--------------------11111111111111111111111111111111111111111111111111111111111111--111---1-11-1------------11----1-------1---------------1--1-142211111111-----------11111111111-11111111211-1111111111111112-1112121111--------11111-2-------------------------------122121111122222222222222122222222111111122211111111121111111-1111111112111111-1-1----------111--1-1-331365-2--------------------1----11111212333313444443344443445434--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--141111122221111111111111111111122222311111111111111111111111111111-111-1111111111111113444433311111-2-221111-------------------------------------1-----------5 1111673-744-66465444644444544445433325553544544445466644454444575554456575755256544444333593536443335435664646QHHGLJICBCBABAEDBIAY*J1JFRAC9BDBDJEBDCC9HCBKAFCBBBOXMQCNKfMXnIOGM3454P53264858C45C348DB83 * b.98 Leukotriene A4 hydrolase N-terminal domain
[ 367] ------1----------------1-----1--1-111111111-2-11111111-------------- -213F3132231--35422-251158222224855566B8341-132--222834--3--6532656DLB5-------5---5-----122---------1---2-111-----------------------------1----1-1111221111111111111111211112111111111432-----1365555566625555657666575553453547899A98112333333333333322112296425B22948AA22965395342322224333322444444444444444444444444356221555422-38222222232536--2444-111-2----78121-5--212111-3-1-533211111113451-11313155555554558-116-1714361-A7765668779A321312553125456--------2332--21-------------------------------222-6FE9A9999995877888BB788856B9EFGF922776232124447754322222631111111111222-42---13--1--2---1--1111----1---1---1--------------------22542231226352222122222222222222----111------65742637776755588-7778743878756667665797562217467676777677777565456664-444354444455--121111111111155611112------1111555552114312887866894755514571111111112333233333344332233333333----111122-------------------1---1---------1-1-----23---612-1--- --111---11-1---1----11----1------1---------------2-1-1--1-1---------------2------11---1----1-112-----1-------2-111111----2------------------1---------------1-----11-21---A-----222J22214-1-2-12--21111 * d.190 Chorismate lyase-like
[ 368] ------------------------222---2-22---------2-32--2-----------222---- ---2--2244422242222-2-22222222222222222212-22222----324212112222-221-212444113332----11322-224-----2323145143--------------------2--2421443233524-222--22222---2---31----4----211---214-2212-2-11-----11-3-1-111111111---1--1-423332322211111111111111111113-222--22---22-----2-2222--111-----11-----------11-121-22221-1--------1122-222222222222-2221----1422-4-22221-2--2-33322-141-4553-------2241-232--22222222222-21311323-22335--33343312222-41--2-----2---------222-2-45--2222221----------------22-22125621111-2222221----11-3------22-3425--2221-13323121-2213---21-------33121--34341-213111113335475441242344444332222224434224224----233--11-1111-111111111111111111111-12-21-1-222-------1111111111-111111111111111111-111---------------------311111112-1--------------1222221111-1221222-222----222222222222-32------------------2444424443111122222-------111131111111-1-122----21122222---22122--2--25--2-1-211----2-222232123--2 532-524-M8B466535654754666633457744443232223225321243433A2544668A9BB5ABAB8B9A798A778976648I85B6CB8456459BD-4I6A4AE9898698A85BB48AF*6-75A9C38A9575777777677355835CD36551F4A387514978*647568FHj3OE384434E * b.4 HSP40/DnaJ peptide-binding domain
[ 369] ------------------------322122213111-122--2121112312211-11111111--12 2221222333323223422-23222222222242323253223221131112211112123222232222212221112113212222-12--11111-11--111111122222221111111-1111111111211132222213211111111-----111111111---1-1---11111-121-1122111112212121222222222112222222322222222222222222222222222222221222221222222222211-22222211111221111111111132121311111222111111112122213333233232122222222222222121112322212322211-1252111111111111111111111111111111111111112121111111111111211111111111111121111111111111112111111111111111111111111111111111111111111111122211111122211122111112211111322122123111311111222222222111322122211222211122121322332222234431312222221111111111121341223111111131111111112111111111111-1121111111124321113344343533-53333243354433333333232123242222323323333221344321411333333333333111122222333331111111111111-12111111111111111111111111111111111111111111111111111111211111111111111111121111111111111121221111-11-1121-1---11-11111111111111121- 2212554-H982433436345444434554555657344544575549343323343543323332342543434542433433332235723527623538464C1463I8B7B855854497CB4A4Mq8194E6256E379556543E54C6B58g2A35969EE45456449434Z44363aBMK5F82156685 * g.54 DnaJ/Hsp40 cysteine-rich domain
[ 370] -------------------------------------------------------------------- -468722322222256655-5E44565555549689547713341-21---11121-1--3233336C97111111332132-112233322-3-----1823-73324--------------1221335222-522222---122233221--11343755-2213343-2-----2-----------13123343434434444442211234442221---------32--------------------14222232321442222223--1---111-1-1-------------------------------------24157443444454523332221-3312123121145324-21---1-22121411422222ADKGECABDEFED8899789898C-JNIKPGHHEI12CDDAIGHGGHGEAB-21D3A8888665111111112--11111-----11-----------------------55511-----1111112111111111111-11111111----12111123112-2141222262222222342232F2211121121111-66626372544-42D773111-1111111111111111112D556631632---334444334555334443441-33432------65444536666666666-66666666666676666676664432376667676677575684656666511323233333333-112AAAA9BBCC91531111111-1111111122222222445255553444426235222---------2111533333443333323233222------31--------------------------------------------111111114191 ----1------1--------1----------------------------------------------------------------------------1-----------1-----------------1-----------------------------1-----1---1-----------------2---------1--- * b.160 L,D-transpeptidase catalytic domain-like
[ 371] 11112211211122222211111223321343444231222322212121211122222222221111 -1137------11-1--44-4-115-434445-----1112----1------212--1--222---1221-----111--111--1--2211-111------22--1-1---------------11111111121---111111111-1-1-1111----1-11-11111---------------3311--11122233222242343-211--423-111---11111122--------------------1-2-11-11-111111111-1-1111--------------------------------------------121--2222222121-111111-111--2---211212323211121-111-12111-----1121-111-------------------3--3-11-1-------1---11--1114112111111--------111--131------------------------------1--1--11113222242111122234444252321111--111-1---13131-1----1-1--------1-222--111---11112211-1--1211122321111----------1-1------------6513-11-2-1121-----21----1-11-11---1121------B9895D8CCCDCCCACB-CBBCDCCCDCCCEBCACCABEF88223DDDDCDDDCDEDDDDEF9999AAB5-A66666666666--22-----22121131-111-1-1----1--122222222321-11112221122221111111111111----1111111111212---------------2----------------1-------------------------212221211111-- 32127451B65234622332232222333333422212222123332233333433422212222222212122222222222222423232222322222522322515B9BBIDA8668895JK7K7Y*D4LAL6668B48C658975E65F8E78556566473967B56753222F2223234453744426542 * d.230 Dodecin subunit-like
[ 372] 22212722555556655154324512241111322241--11-3334232255532221412333111 46712111111-1-1-122-22--1122222-122211221451111-11-1121-11--1331312143-222222243562312-16567-533---22121213-2--------------173352414354111343221-4378336233332421244465587-21----22-1-1-1--2141233333344343535351355223333223134222222344444444444444443442221-12211111331122221-11222333333434433333333333333333333333333333333333546C4346556978656655647431426552756181342411-3225-262333-----234343235664521222222222-66467368352143333323442343-12-2413111123333333312222515------------1111111111111-----342422111322222323333223533333322322321112313322323511333252432-------1126451I6511342512332474679644455469252111------221-------22-2211445312322144544455532334355364--113231-----43343434445444444-4444445444454444444444234534344444444444444344344342-333333333322--112122211112222333322223323211223333332331334245435344444233---------14455444442344431434334441111114-111111--------3-2------------------1------54343645562633 1--------------111-1112111-11-1--1111222122-1---111111111-1111------------------------------1---------------2---1----1--------1---1---------------------------1--1-21-----1----1244I3332--14-111-3---11 * d.350 YcgL-like
[ 373] ----------------1--------11----11-----1111121141------1111111------- 1111111111111121111-11111111111112221111111111111111111111111111111111111111111111111111111211111--11111111111111111111111111111111111111111111112232553322222222233123334222222222222-----11122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222222222222222222112222122222222222222-21--1111111111111111111111111111111111-11111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111211111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111-11111111111--111112111211112-112111111111122222122211111--111111111111111111111111111111111111111111111111111111111111111111111--1111111111111111111111111111111111111111111111111111111111111111111111111111111111111311111-111111111111111111122212222221121 11-1841-B592EH797C75999BAA7888888989776777788896787B7776A768774553333644354432343667966565EB7EFC75795C4766-36AB757B594455456784D4Df9295F44557357265543965D47555288565t6777C676F2841923266GJIJ9JK3146782 * a.149 RNase III domain-like
[ 374] ------1----------------1---21--1--1---111111---3-----3------------1- 11213--22221-1-11----111-------------1--223341--2----231----221-4121431----1------3----------------11-111-1-1---------------1----------32246---42642133211--------22115532------------425-1----2222222222222222223222222213243131111115212222221222222111111321--------11--11---12-----------1------1-------------------1---------25214222222212125112211224-442-1111234-2311-112-11-122112-------2221112132111111111111-32222221111-11-11111111111-2-2432222212-----------1-1----------------------------------21------1----------11---------1--2----21-22--------------------11111---2--1--------------121-11--21111461---1-1-----------------1-1-------11---1-----1----------------2-----------11------------------------------------11-------------------1------------------------------1111--4-----------------111111----1111111221111121222-------------1------1-------------1------522----111111111-------------------------------------11-1 1-55EC4-1---CB345353332432133-111-2-13233332325533545654612333235343162252223132255533---24153481123-725121156*GJCCILDBD9GCCQJDMBg*H-LFZBEEBJBCFDCEECBF99JBECLKfYDPNKR9aLb9Lj*81EY2----E1BQGP2ME1IXRTb1 * d.111 PR-1-like
[ 375] ------1122222222-----------1---1-----------------1-----------122--11 12211-1-221------12-1----111111--------------11--11-121-------1-11-12---1111-1--11-1-2211111-111-1111111-2131111111111111111222211-12111---------212244-11--11--21-11243611-11----111--111111111-1111111-1-1-111122211--21111-111111112-----------------11---1-1111111-1---11-1-------1111----11-----------1111111111111111222---1-------------------------1--1--11111-1-1-11--1--11122311117515214542111213111111111111-21111111111-11111111121141111112232221111111111122211121111111121--1111111111111111111322223333444454355543353555635642243513334212222212423323322421111111223123352122211122221121133321333343221211122222222222222253121112311122221223222323222322353321-122111--11132332332222222222-232232222222312211223233342333323322333333342333222112222222222221121111-1222211332111111111111111112111121142777744243243241321111111112222322222332222122112222111111311122221111111122----------------------------11--1-1-2211 ----561-334133242212322333233322232223443552323523333222233432332253333252423-22422121221262224222223122623424LECCECD9878999DE8G7R*E1GCS8B69E99978B967E89G6787A7KVHL9QDYLah9EBJ13-2J-112354662142223351 * a.250 IpaD-like
[ 376] -------------------------------------------------------------------- 1-1-2111111---3------2--24-----132221334-1111-2-----1311------2-2-2122--111-------2---------------------1-------------------11---------1---------------------------------1------------111--11-------------1----132--11-------2--1-----21----------------------1--------------------------------------------------------------------4-------------1-------1----1----33-------------1----111--------W67--57387511111111115-22222222B1--14433396336653---46741453241111111111111-1-----------1------------------1-----Q****12232121111221111111121D****9G433I8sji*e*4**4A1-----------------22----2-1------1----------1111-1-----------1------------------1-1--111----------------------------------1112--1-----1-1-------11--1--1-11-112111--31-11111111111111112-----------------------------------1285----11--------11112111-2-3111111222312122222-------------1------11-1-121111111------------11------------------------------------------2------- ----11----1-12-2112132312-12111112111-1--1111122111212112--211111-21-1-1111-----111111---12111111211111111-11-7211112-11-1--21-23383123311111-111-21--1--11---L----1-31-26---3--11-5---11421l3132112-11 * a.288 UraD-like
[ 377] 11-----------------------------------------11--1-1------------11---- 2362622222222253333-342234333333344445CB2733332231113633321154226498752222222222223333334323-3223--232225232222222222222222222222222222333342224344344442233333333333654563333333333333332233112133333333233333311111133422211222222221122222212222222222222212112111112211222221112221111111122111111111111111111111111211111111121133222222223212332222222321222222212211111112211332222422222233442223222222222222223-24224332232233332332322232222234323322222222222322222222222222222--11111111111112122-2223233324734445557776566888837734555322323323223222422222322322222222222233323222232242222212122131335355222112122222222222222222222223332332222322222232222222222331-22222------24233232433244443-3123223325343222223433336533433432333333332422222232-3777777477761122222222222224331111111111111113333333222425555344355335343311111111124343333333443322324224452222222233333311121-1-33--------------------------22234322332222 34--211-711111211221121111211-11111111111111112111111121121111121111111111111-1111-1111111311111111112113211412--12-11-1---------4C5-2----1-1-1--1----11-12-11132-1---------2--2484k33344DCAO1IB3442213 * a.174 Double Clp-N motif
[ 378] ---------------1-1----------1---1--1-1---11--1----111-----1------1-- ------------------------------------1--1---------------------1-----------------------------1-----------------------------------------------------1-----1-----------1--111--------1---------------------2------1-1-------1-1---1--------11---------------1--------------------------2-1-1------------------------------------1-----------------1----11---11------2--1--------------1-------1-------1-1------1----------------------11------1-11-2-1-----1----11--11111111----------1--------11----1-11-11----------------1--1-11----11-11-----2-----------1-11-11---1---1-1----------1---1--1--------1----1---2--------1--------------2---------1---------31---------1------------------------111-1-1------------------------------------1-1-------------1-----------------------------------1-11-11------1-------1----11-1----2--1--1----1----1-1---------------------------------------------------------1--------------111-11---11---1---1------- C956A98-U77665865559675D8C75464566676767698555559878B857986756555545246444646266556476565685558975544A666746B9aNdXROYIFIFFFHbTEgEy*W3bQrEKECX9HMFBMGEDUCEiHOHLHCA99ABQBC9CDBFA9C686X54457DBDE7FB5779BA4 * e.25 Sec1/munc18-like (SM) proteins
[ 379] ------1-----------1-----22222222-----------1111211111------11---1--- 312---------------------------------------1--------1------------11---------------111-1213322122231122122723221111111121111111121111-111211121113253222232222222222322323222223222223321121111112222222122322122222112222222222231111112211129211211112111111221122111121111221221212222223111122-11111111111211111211122111332111222432554555635462332322333132321122321334122322111113111111111111111111111111111111112-111111111121111111112111111112121111112111111113112111111111111111111111111111111111-11111111112221221111111111111112211111-1111112-11111111111211111111111222111111211122111111222222211111221111-------------------1-11-111111111111111111111111111111111-2211111-11111111111111111111-1111211111111111111111111111111111111111111111111111-111111111111--11111111111211111111111111-111111111111211111111111-1111111211111111111222111111111111111111111111--1111111111111211212-------1-----------------13121111111111 43226771E564655678747766659776676767877776686758766686678765664534743766544763776887774546A677695567776C752885HA8687765655769A3E4**B1F8C55679577375668856A697456CE57564664736876366T55446946A77I3567653 * a.113 DNA repair protein MutS, domain III
[ 380] -----------------113122122221122-----------1111111222----------1---- 433---------------------------------------------------------111-------------------121221443313223--332338362211111111112222134333332343222221112322222222222222222222322222222222222222212222122233333233333333333222233312133232222223333333333333333322222322133123322222332222112222222---3221222222222222111211111113222222222244524434434243544433347221222-2355433322342332131242111111111111111111111111111111111-111111111111111111111111111111111111111111111111--11211112111111--111111111111111111-111111111-1111111111111111111111111111--111111-1111111111A21111-------112111222223333343332222222213343335122--1-------11111111111221331111211212111111111111111111111---22612-11111111111111111111-1111111111111111111111111111111111111111111111111111-1111111111111112-----11112-1121111111111111112222222222212222121211212222222222222211111111111111111111111111111332122222222222212211-------------------------22222122211112 3322654-C55245566464555554666565656565554556556655555645666566443453-564334653555445653336D566766565746665289484655474444553672C3*s8-8395544635634542564574754526E3437323263575767Ay77658A56858C5655555 * d.203 DsrC, the gamma subunit of dissimilatory sulfite reductase
[ 381] 33333333333333334344343333333333333333333333333333333333233333333322 1111111111111118111-12111311111148251232111111131111111111111111111221111111111111111111111111111--111122111111111111111111112111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111-1111111111111111111111-11121111121111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111111111211112211111111321111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111-1111111111132111112222222122-22221222112222222222221111111111111112111121221222211222222221222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112112111111111111111-111111111111111111111111111111111 44335443D7734444333544436334444444444534444444444444444454333332333313322333533333441167748333435464433A9G4454877444542F8473aQ3Z5e*J-CGu2257d43M423469723G374455454446384B457535544b44334GBFO3973455553 * d.12 Ribosomal proteins S24e, L23 and L15e
[ 382] ------------------------------2------------------------------111---- 343-2---------11111-11111111111111111111111151-211111211111112112-122211111111----123444EEH93C68---222222212111111111111111-2232322243211111---21731122122221111111113214111111111111142111111311333333333344344221112334111111111111112-1111111111111111111111211211111111111211112321111111111111111111111-111111111111111111111211111111111111211111111-1111111111113211111112122132644333333536344443433633333333334-2252453443426557333444333334334335333346666666658645A43123333331111333313333333333333346433433343353353333336932333334656783386543465335353336464454333433333343845445357464786254597554C4434445411-1111111111111111112111865652455335455555554555445444441-3534431233344444544444454344-44445544454544444456444444444444444444454444444444451544444444444--8445555333344443333333333333333333333333375555554565555545551111111113644444444445444444544444444433G-11----111111111117DF13--13112-11111--1111112111111112232 1-------1-----------------------------------------11-1---------------------------------------------1--------1-------1-----1-13-1-121-121----1--11-----1--2-1-1-----1------2----121--1111----1---1-1---- * a.55 IHF-like DNA-binding proteins
[ 383] 11111111111111111221121111112111111222111111112111112122122222111111 2223222222222222222-22222222222222222222222222222222222222222222222232222222222222222222332222222222222222222222222222222223222222222222222222222222222222222222222232222222222222222222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222221222222222222222222222222222222222222222222222222222-322222222221122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 11111111522123333332333332233233333333332333331333333333333311333344234234344444433333444353344333333534551251213112112C32318C14-3C3-125-126211213122-12-1221111151312-224311124353p3333588EG3651111112 * d.141 Ribosomal protein L6
[ 384] 22-1121111111111-1--2--1-11-----1--11------1-2211212111-11111111---- 32322111----4----11-11--2111111-2111-1111-1-----1--1-----------2----12-2222333112--222--222212-1---14221512-2---------------11111111111211-----1-233522211332212221421325-121111131111111111-11--111111----111---1----1-1------1-1111--2-11111111111111111-12211231221411442121133122234333332221111111111133333333333331332333333-2-11-------2-2-211134311111-31-----1--11-1---1111--2111------23122--22--1122222221223-43334533131-422321-143--221-1111----1112222222244432--1-------------------------------23-21-1125555555544355645555248542313-1544212--21-12111-----232221222---1113242131211311111-1-11-22222242-11----11111------------3323322-111112111211211211121112111--112--------321-2312222222222-2222222222222222223444-1--1333233333333332232222222--222221212222---1-----222221111111311--1-----11111111----1-------2-2-2--1-1111111111-123111111111113213233223----1111221122--------1-1-------------------------1-----1----321 ----778-733-23424445443633533434444334343344333433463543433343433212-42233312-11233334-2435443533233344322-5CAE9E9KEI88777D9PN7G9e*E1EDN6877E899468875A67I899C96AB9A874A584BDA62576I44469A8CC5AA82D9EA6 * f.20 Clc chloride channel
[ 385] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------1----------------1-----------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1------------------------1---------------------1-------------------------------------------1----------I-*****peJGMIMSNdfKbN**Y-mSpHQIEbHQaIBPKMFPKCmOcLQXCNdl**E5ODCtx**--21-----2----------2--11 * f.36 Neurotransmitter-gated ion-channel transmembrane pore
[ 386] ------------------2---111221-1111111--1111121-11-1212-1-1-111------- 3232322222222253344-4333334444423333456A322223232111243323--22433454443222222221223222222222-2112--121111222111111111111111122232223232--------2122222222222322222221222222221222231222322222233322222222222222233333322233333331111113322222222222222122222111111111111111111111111111111111111111111111111111111112111111222111133322222222222233222111323113434344333343333333211421566522222333332232222344444444444-2242222344215556555555553353424333334522222222254433434---11---11223222232332222111123333344443555555444445555444545655565511555744644445433444334542333332332345395324331433331455254332443424532111111111111111111-21-11224425344343344445433444345333441-24342------33333323334342333-3334222423333333333433334343333222222343332533232232-4444443344451113433335555237362222321111122223333333333456666454644454455522222222232434555543354444444444443333--43445544222222221-1-------------------------31133322223411 ------1-2------------------------1--1111211---1---1--1-----111-1------1-1---1-1-1-------11---121-1--1-1221-1--3142131121111123211231-11211211111111111111213222131-312------222---------1--13-1-1126--- * d.194 CNF1/YfiH-like putative cysteine hydrolases
[ 387] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111222111111111111111111211111111111111111111111114111111111121211111111111121211111111121111121111111221112222113322323251211111333112212211111121-11111111111111122212111111111111111111111111111112222111111111111111121111111111111111111111321111111111121121111-1211111122221111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111121111111111121112111111111222111111112111112111121112111111111111111211111111211131213322132332321121211111111111111111211111121122212221-121111111222223111111111111111111111111111221111111111111111111111111211111-111111111111-111111111111111-1111111111111111111111121111-111111111111111111111111111111111111111211111111112111111111112111111111111111111111111111111111112222222221111111111-11111111111111111111111111111111111111111111-111111111111111111121111111111111 33112272833255322212222222322222234312222222222221223212221311212232222-12213122222211433253234522224424362572EJEGGFK9C7A9DBKNCTDZ*F2IHeBD9DIBCICCDFABCA9KDFAEC7DB8B9B9M6GJAE754353d433435A8D2764563334 * a.16 S15/NS1 RNA-binding domain
[ 388] ------------------------------------------------1-------------1----- 1--------------------------------------------------------------------------------------------------1----------------------------1-----------------------------------------------------------------------------------------------------------------------111-----------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------1-----------------------------------------------1---------------------------1-------------------------------------1---11-------------------------------------------------------------------------------------------------------------------------------- -11261C-1--1----1---1111---12-------1-----------3-1---1-----1-------------------1----1------11----11-------1-1*Vdc*pZNDDDQPIvgEjJy*X2jUuHGIBUJOjTFRMEBx9EoBeMMZQ**K*KG9EB9zAB*V--112-21--5946-4--1----- * f.12 Head and neck region of the ectodomain of NDV fusion glycoprotein
[ 389] ----2--------2---1-----3-22--2--27269--622424221-686H-3-----22-2---5 122--229---4-7---22-24--1-23222-24242-2--654-6-44----232----2-2-4-31212-----445348---2-4-DDD--3-----3343-622---------------12464A9--914444-61--4-6-58989--22------443-6974--2----------4-11----22-----33----2-----66-----5621---4-41-422-44446424444444-2322---4-3--45--286-7-7-2--2-21221143332866869698883333333333333-89673777217--2222-42132-4-552-2---4-922D3--55--745222-222-244A2223-----24212-5--2-2-3333333333----1-------32-----224--22-3-22--1--4-44287888888---3-----------1----2-24-2--2-22----------24---2---2-----------3-21-22132-2--2-4-4322--438-C--C2622-245---4-6215222-6H---8-3643--422A--C3212-2122-2245-423652359A79B7854-2-AA--83B1-2-24-96-B44-A-44-6-19-2--2E534-------216A-3224222224--22--246-222221-22-422-4432122321-3242-2222-222-222-------5----232--1---------293322666332-646686B2----143482142-42-2--22-2-842-511-17-112-244323A252226-2255754448475--2411--f7--------6-5-1-5--5--AC22---4-4HA-5672-4-2------43- -1----1----1--3-1--22111-1-111--1--1-2121-----121-2114-----111-1--11-------1-1--1--111----111253-----1--21-41-5122-111-2-12-51-3-4B33317---1-12-1-2-221--1-11---1--1-41-31F--1-1-5------1-1-1-3---1-3-- * d.287 DNA methylase specificity domain
[ 390] -------------------------------11-1--------------------------------- ----1----------------------------------1--------------------1---1---------------------------------------1-1------------------------------------------------------------11---------------------1-------11--------------------------------------------------------11-----------1-------------------------------------------------------------1-1-----------1----------------------------------------------------------------------------------------------11111111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-----------------------------------------------------------------------------------------------------------------1111-----------------1---------------------1----------------------1--------------------------------------------------------------1--------------------- 1111pXZ-845-55544444444454444544444445445444554456655555458565545444244543554-4444244444436445453444423433-UF8bKVRUQSMHDJMPLSRHtN**R1UP*JLMMSMJMQ6MJG5MIIyLOMNMIz*DTH43F8DK84QW2324A2233343874351456888 * b.64 Mannose 6-phosphate receptor domain
[ 391] 11------1111111---111---2111--11----------------------------1111---- 1212311111112132222-211122222221333323531333233322124353332233323273333-----------4-----11---1--2113334333313222222222222221---1----11-57633---33111111111111111111111111111111111111144444---224444444443443444474464444455344322222242233333333333333344432-1-22-1---111111111111111222222223322222-222222222222222222322222222211---2222222-2--222---------2-------1------1122--23-2411222222124223222222255555533444-225225232322233231533343233234242222232222222222221212211122222111122222222222222222236831232233332243333322233333253333333232232222222333222211112222222221224222-2-1----------2231324--113133-21-----------------------1113223323343334333333333333333431-1432212111132222222222233322-222223322223222222323322222222222222222222222222222212222222222222223333333333213232222222222222224444424222324444333333333222222222222211223222223323333333332222222111-222221----------111111---211--111131-11-------------1323 22--343-313-3323222343333333333233333433332333123333433331233332222222222222222221112222233323434333443443-24362433353133333543417U3-53A2313333533332333451742338634231111A43234423e2222468B93654332223 * a.9 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
[ 392] 1112111-11111111311111152222222425122343332322222AGCD122112111111122 3252422222213133333-53223333333334443333233322223222233222--3331433345211111111--3221321443322---11-212323222--------11-----3223123324332312---3133433333333333333333334442333222323323333333-232444444442444444434432444333322222222235111111111111111111121-1-22-----1111221---1-222---111122222222222222-------------2112211111262333333333232333321113251133232GO6424322A33322-33132224-----225333223332422222222223143233233443-4333334333443222334345445432222222222222322-----------------------------1222312222234444333344331344443443244532333333253334433333322221-------2222221574212222222212321222233333353231----111--11-1111113212311344322322233333334333333343344--1123311-11134343333333333333-3333333333333333333333442133332333333333333432333332-42133332333311-4-----122233423111122-11111-11322221222222222222232222233321--11111-334343333344444222222222212221321222222--------1-1----1-111211111111111111121322323331422 ----212-21--112111111-1121-111111111-1212221--121111111111111-121-11-1---11------1111--1-2--1-1-12111--222-132323222-212-22223242BN2-23812121-11112311311323122--61623------12-1121Q222213-141224242311 * a.46 Methionine synthase domain-like
[ 393] --------------------------------------------------11---------------- 2221211111122132254-42223455555244442233231312212121121212112221412312211111111111211211111111--1--1111131121--------------122111112122122231112135352221111111111311244421111111111111----111113222226433545335131222554222233332222211111111111111111222111121111111221112111121111111111111111111111111111111111111111221112221121111111111121111111111-1--122111111111111--11111312222111111416343234263333323232332-33233533434263322254333453243222523522322222222244241421111111111221111111111111121122214332233155453221222243222213426283513222414115433323332121221122221124111213111311222221222332233111113211111111111111111111111111441212222174343333243333334323331-1111111-11132131322222222122-2222222222222222222344223332221222222212112213111121133333233333311121111122223142211111211222111133424241113233233753233332212211111111123341111141311223333422211111112331122----------1----1-1111111---11111111111111111112211 11--452-721-225247557979G993325343537646442422575D56A8337644432113131133132332132122123329E543534332222523-652B4A88632311455553627K7-444112141264232-252-74632622236331313243382134M223-4968B72812452-2 * b.93 Epsilon subunit of F1F0-ATP synthase N-terminal domain
[ 394] 11--122344444445-22222222---1222-------------1-1116---222--11331--11 32--112233611253111-14--3411111253244477-423422113312152-3--1112215422211111-1---13-1---3363-1111---312-32413111111111122221111---1111--1121---3272423352222112111222344662311222241221-211---22122222322224222221332122211--21122222212222222222222221211112-111111-------111-111-111111----1--22222222221---------------------------1-------1-2----1221111--11--1-------1-111------1-3111----1534452233322311111111112-54333233----11112224431124--121342214322122222235522142---1----21-1--11-11---11-3-33-1-1---33112223219111122161112-1-434221--33-352--211-21251-22311111111111111131-122-------1-------2----1-66------1111111--1111111-------11112323212--1--3--11112---1-2---22-2-1-----222-11--1-----------1---------------454-1-2-21-13111111111111------------------------11111134441-232111----1111---165646351-12166777777386793567----------111122222131-111222225332111--11442222--------1-------------1------1-----------1-1311--1 3111134-B2--3264465723243623333332321223422465355548694436253545634445563536647643343554538544767553222589-1I6EBC54794376486EC5D5OrB-C9H4464A558547663C53A5A646752867B4F67325632457J45383969C7A9A646516 * a.132 Heme oxygenase-like
[ 395] ------------------------------------------------------1-1--1-------- 2222422222222243233-33114434444443334444222232332222222222224423424555224444222222212222222222222222222223222222222222222222222222222223333322212222222222222222222222221222222222223233222222223222222222222221223333212222122222222222122222222222221222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222-2222212222221222222222122221222222222222222222222222222222222122222222222222222221222222222222222222222222222222221222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222223333333212222122222222222221222222222212232222222222222222222222222222223322222222222222222222222222222-2222222222212232333452323133-4333334333433332332333333333233333333333333332222-222332333323333222222221222222222333232322223223333433322222333333232222223332222222222322233333333332222222122222222222222222222222222222222-222222222222222222222222222223222 21--111-2---2222322222322222224232222212222222212222222222231332223221222222222231112211112132131223121223-14113623314111-21453728K2121212112-242212342422232242-11311-312111313334J4423363342341221111 * d.325 L28p-like
[ 396] 11--11847777777A276462343111--11--53382222241-2-417762-2-222-1351--1 2-151------11123222-22221322222321213775151311--311-32233111224-1-1235211111112111-5C4661122-233------5-21-2----------------16755745634333441111414--33111111-2---121-----1----11----121211441221--1-1112-111111--22-11112311131------21122111211122211112--2---21-----11--11--21------------------------------------------------1-22-433333323231233123131411--2324533323235-15243-1222---------165422321232------------143-6-41-1--1--311-311-1111112111211335111111113112-711-----------------------------12112--1----1121------1112------2111223212211313131231-12-A11-12----------1-2-642135634654413233122435444122621131111111-1-------31323995645615454357777469777556675653--176G33333355357648888888888-8888888888888888887778566655655555555545455566777783-477777777777--35-----11114764544444433332433433333332323466766555565654543---------83335444444434411215111111111455211------------4---------------------------211114444411-- -1--112-322111111111111-1-1--11111111-1----1111111211111111111121111111212111111111111211---11-1-112112111131141112-22-2-12123-223N11125111--11-1-31--2-13133121--2112--232131311-1D2111112121112122211 * c.114 DsrEFH-like
[ 397] 11---12111111112-132231111111211312---1--1--------221-111----221--11 1132721233321242333-33223433333322222483242225211231323225--222232444411111111-1114113331111-1-----1211111211--------------12222223222211111---42221111111111121111111111111111111111122111---32322222222222222233332322232322121111113211111111111111111121-----------------------1-1----11112111-1211---1-------------111111111----11-------1--1-221---1111-142--1211-----1------21-1433311111214331122211111111111113-11212312343134412333341111132213111112122222222211111221111111111-1111111111111121211112112534555544634455337744442353A6B871244221122421155225112122222222211211123422-21-33----222241311111123-2311111111111311111112111211221233223232222222222222233222--13222------31111113333333333-3324333333333332333333223313433333333333333222222221-111111111111--1222222222212522-----1-----11112231222232232222222222222232211111111111213222222222222222222221111112-222222------------------1------------------11-21-1211111 321-652-7211665555344656766333333333533343343434354454464543535222211233221343332111112334945645233455223315248643356233234495362En7-71B43555357547525732433A4437855544648D88455553i34254B4884984154525 * a.103 Citrate synthase
[ 398] ------------------------1--11-11---1------------11111-------------11 2222411111111122233-321122333332222222322222222211114222211133212232221-----------212111------------211122322--------1-----1---------3-11111---21233333211112223222222433312221112121311211---3435555556535565453533345544444545222222851222222222222124222222415512212333344211---111---------------------------------------------11-11-11---111-1---133-1---3--2-21---------------212222222222553442224444433332333333-33433433242222234443333355222223333322222222222233133341222222222222222222222222222232242322222222222322222236222222256333222222633333623332233333222222222222244121-1111112222----1-1---222233411------------------------543343333333333333333333333333333--342333333344343434444444444-444444444444444444444444444444444444444444444434444324444444444443333222222222533333333333333333333333333444433333333433333433322222222223333333333343344555554445544443------------------------------------------1----------52-1 33--222-72212322222222222123323222232212222222222232223222221222222312322222222222222222212222222222222333-25234223211222223341236F3-435321221232222222332433232122211-224513322332S2223375591455352323 * b.124 HesB-like domain
[ 399] --51-332A34B88WF-63-2V6-A8A7E7LU-4-123-----211-1246H61342172614A4-1- 21--1-12---1---1155-54--1154545132222199-19R1121-111111--1--332121C4514----71--1-2-2--341111-1-------------7-----------1111------------7-12----4-23e5RL*j*1111----22Y1CP24-------------68----13G24545568D45533682-2212446bA121F3-11111611111111-11111112112216-21129-Q2115533-3------------------------------------------11---111-5412211111151613B44174N471-5-121733E21--2-111-6--6----11--------111---11--1-------1------2-3111--1-111111111111-1-11-2-----1-211111111311--11-------------------------------1111-11-11977-39-1111--11----1-2-1--1---211------D1----------------------3-1-22---2--1-11--11111112-----1111---------3-2-51-----1----3-1--13-11251--------3------------2N-1-------11--4112333212143-33253224243142222221111-11C1-1211121112222242222334--111111111111---111--------1121--1111---1--541211121112J512222----1-----1----------------------1--411111111111-32----------1--5--1-----------------------------1-54-82846D2-- ----1-1---11--1-21--222---11111--1111111111222111-1-11--111--11--111-1-----1--------1---111121121111211111-11-3221123212-4322-1414C2-44511224123-2121211131-22211111-3---3--1---XL241--U4EIJW1QC1-2-241 * g.72 SBT domain
[ 400] 1113112222222222-2213115211111111111121111111112-2222424334432--1-21 2131422222322222322-22113222222332222232122421223232222132--2322333553212223321121122333343313221--34433333341222222111----211111111211444221114222222223233323233222232223222322232233443322226489989977799887745544477A656565644445456333444334333333333433-2-32-42-1322233121-21211311----111------------------------111--1111-36343663453436434654222324--41132444633224344331133152222-11-1323333233343322222222212122222222223-2333332333222332322222222222222222223322322-----------------------------2222222222311121111111112211111111222221111121122122221233222231221111111122211112221111111-2222232231122221132223222222-1-------21242112223243233222222223222222222221--143311111122222222222222222-2222222222222222222222332222223232222222232222222222-22222222222211-3-----111132233333322122112113222222222233333334333333423431----1---2222333333222232222222222222222233333331111111111--------11------------1---12111313332213 ------1-312-11121232122241211111121112122211111111213111222211112111-1111111111111121111312111111121221221-2412112114213422332131352-324523222443134123-121312211--22-1-1-1-33-1132B1112155673552312222 * a.204 all-alpha NTP pyrophosphatases
[ 401] 74224B99IEFHIH8F8453322I94458763----1------1--2A--2---A33DC242213-33 4441111111111131133-321111322331112223331241162312223111121133211111111122211121131--1--2211--11----111133343--------------232456612B122224533421G7685692222445322562944432232222222221224522-B454444465644666857555644444626321222222352111111111111112111141112213212441135121121-22-----12-521--11111111-------------111---111167477454565334373432322624233326989D4BA535833441---218343--1-132112-1136547----------1-21--132-44416236345653162412123323112116666666624431221------------3155233331441----13246-111135456554111155221-11213744242-3312432212422353171112112332332932411131312311412211462542A13222111151----------------------1-87122222121111111112211112231111--26135------11231224331423243-3235542434332224222333613433213212122234332232431121-311111111211--5111111111132111222111-33322311----------2211113112221131213---------1---1-----11---22535333333122-11-442232--------51-----1-111111111111-111111------1---1111 -----------------------1-1------------------------1-1----------------1-------------------------------------1---121--2-1--1113312136111-311-1311131111111-311121---1------1---------------2--11-----2--- * b.129 Double-split beta-barrel
[ 402] -----1------------1--------11-1----1-------------------------------- 334------------------1---1-------1111----321--------------------111---------------1111--111-----------------1---------------1---------1----------1--2---22-----311411111-2-2--1-11-----1---23D-------------1---1----------1---1-------1--------------------------------11-----------------------------------------------------------1-1-----1--1--1111------11---212212-11-11111-14-117133335331112231-1-2--222222-2121----4-32---3--3-----2---11-234311--1-------------11221-----------11---1-1-11-11111----4-323-2--13979BDDA98877698BCBD78DE73629-187GA344566567A221886B5-4IE56CA787B45334451---13----5555855B645346251-1112--1------------1-3111-575458558666688745667864677775--12556------514713547764BAB79-844897F7777B7A54AA7454652343221222232232312464721221-C77699877A98--97122116666349212-246232125-GH34355437373568AC8A678677796243432123123388577777755755A877676444A888--1-222222---------------1----------1-------------------121- 1-11--2-3-13---111-1----1--23--1-1---------21211----11124-111111--1--11-1-1------11111-1-2-11-2311121311----6331-132-1211221311115P2-2-1-21-1--1323124-311321131-113212312-1111-5427--411-235162113--12 * d.24 Pili subunits
[ 403] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -1----1------------------------1---------------1-------------------------------------2------------------------is*o*iaVLOGScQ**M*T**d8*k*OSLOwQXoRAURJEgLHzQZWdSANI6MHA4D66KAB92------------------------ * g.76 Hormone receptor domain
[ 404] ---1--1222222235-32331-131111111-111-11111--1---------11111111----11 232261213361128BB66-6C2269656666BCDDACHB153713223111224313--76B22255431-111111-7ZC411-1122222222---1211121212211-111111111111342222231123322---2122-21122222222211-21122431221122211112211111-2212222211212221121222122221213122-1111-111111111111111112111111-311212-21----------------------11-------------------------11---1111382221111111-111132--1-111--12214JF2312112----2-11222222211111537582322324211111111112-43433634342122222222222227332213213312311111111222-222311211111111111111111111111111218A215654343365322222552822221253466872244252133362355113322132-------1223231311-111212332-321341121331324121111-------12111111112-11113332112224254444234445746437541-13123------22551332223232322-2222222222231222223565443313233333333343433211211112-222222222222--2111111----111122221111111-111133223222116233132231145551222111111111133334434433333----------1111221-331121-11------------1---------------1----------1---2112 11----3-421-11123222231334333111143233332332331111237B2111121113211212111111212214433311147332352222211314-1122211132111-12-12-122H1-23211-12121--1-1111-11231113-13111412E32121132N2233232462322154331 * d.168 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
[ 405] 2233222222322222-22222241111121133544353543222224344442222223222--22 2321611122111121211-11111111111111112111244321111211211111114511423334211111--111222222211111111-1-121112111212111122111111-111111111311111111131222222222222222222222322312221112122122222---22343434333233433353333343423233111111114311121222221112211111113222211113211222132121-1111111112121111111111111111111111121111-111123212111111121223332111112112133333333332432112112222222221111123111122533222222222224-112112123221234322333245221112142222111111111111111222322222111--11111111111111111111123122222232243332333445522222332A334311222341223213212222222342222222222522123223222432221232232222222211132233233333323222222222322223333322322332222333222222322331-12223------44322323444333443-433444444444433333344433322444422423324444333344442223323333333331222111112222223323322222111122232222211112222222223322222222211111111112323222222222222222221121111112122223311111211-------------------1----1---11111111112111 1111111-521-1121234436246462322122422232222222423563453322222222522213323234425435534221212222312431111221-15124111111--122213111161-113-11111114111-111144111411B1-1111122132111126111-133392311131231 * c.34 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
[ 406] -----------1---------------------------------------1---------------- 3331222222212122222-22112222222122222222222223112111121111113221211222122222221112122343111111111111111111111222222222222222111111111112222222221222122232222222222222222222222222222222111222111111111111121121221111111111211111111111111111111111111211111111111112111111111111111111112121111111111111111111111111111111111111121322222222221122221111221-2111233221322212221211122222211111232223223333222222222222-22222212222122223332223233322222222223222222222222232221111111111111211111212112111112322232333333333333333332333333333222323332332222333333243333233333333233333334444643444441444454444333323242232111111111111111122122443333333343333333443333332443442-2333311211133322332222222222-2222222222222222222333224334333333333333333222222222122222222222211232222233334333333333323332333333333333333333333333333333333111111111333332222233333333333333322223331332233111111112311111---------------------11111211122311 1111232-3-121221122122122212311111111111111111211112111112211211211112111121222111111122312111111111-21312221132444433142222BA283Kl6-82E2332323511213-5138233341132111-111343212122F2222333362762353332 * a.173 Poly A polymerase C-terminal region-like
[ 407] -------------------------------------------------------------------- ----------------------------------------------------------11---------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ ------2-21-11---1-1-21--1-12221-2--11-1-----1--3--1112-1111-----------1----11111---------1211211---1--------41mRZhVUWVPKLVhV*zT*U***1*j*PXSKpVUcXIUTLJcKGRGSQYcLQH5GC95D6AD6MI---------------22---1-211 * g.7 Snake toxin-like
[ 408] 111-1111111111111111111111111111211111111121111211111111111111111111 1251111111111111111-1111111111111111111111111111111211111111131211111111111111-11-1111214442242212222222312221111111111111111111222221111132111111111112----1--1-111111111-1--11---1--22222111-13---------------111112---111121111111134122222222122221111211-----------------------------------------1---------------------------133-32222222323-21133322222121222332324111111211--212211211111114335423333322122222223122222222211121112231121111111111111111111111111222221221111111111111111211111111111112121133334333333333333333333333323233322223332222234334333222333333333433442334332222232222322223423323321231211111111112111111112112113322223343323223323223223243222-2241122222222332222222222122-2222222222222222222222224322222222223222222222222232122222222222222221111133332322322232322222322233323233323233434343334343333233333333222243333323333443333333333333221331111111111111121111------------1--------12211111111223 4322332-7223222222123223233332232333222222222222222322222222222223322232222231333222222222222243323321223322726342314424323356372Ib7174844434333433214343A1343249E26343212422522433f33333477B2654353333 * b.53 Ribosomal protein L25-like
[ 409] --1-1--1111111--------------1-1------------------------------------- ---2322111112231111-11--14111111133313221---21312221434114--12224572431-------44653--1-------2----------1-----------1----------------1-32255777311-1--------------------1-------------3444222--326666666747666665344327664325467555556243333333333333334343455635643445882265475225756555644643333333533333474474446446457655266661644555555568671355555495-554671266-214942-4321321--1-----------12----------122-222-24-11111-1114--311-233552332----1------2----------2111---2-------------1----------------11---------112111211111213332112121111--11-2----1-4--1----211----------11--1---11--2-12222---------1--1-32-------------1---------1-----12-111-----1-----------1----1---1----------24--32-1111121211--111211111-111111112221---2-1--1-----------111-111---211111111111---------11111--2-111211--------1---------11111111-------1--22----------2111------11--22112111---------1--------------1-862A22-2131222---3332222224733223323---- -1--133-41--54343521211312422233211112111114233449346533423222415113-1321143213322113111212233514355111144123176656AI5666795JD6D3Pp51IEU44467289963783763O7745932258354-325641-122181311161192451246131 * c.119 DAK1/DegV-like
[ 410] 22---16333333337-12-2---62252123---------------1---1-11------1----11 1452211111111131111-151121111112322336342452111111111111111122413222223--------1---22421111--1--211-434262233--------------33-1111--2--23323---25132211211222122233213534211111111211212133---23222222323222222223332332225543221112114221112111111111111111--1--1-2----------1-1------------1------------------------------------------------1----11-----11--2---1------1-----1----2-423351111134765643333443344344344413584393556314443856665983222243555553452222222233322431331223231111111111111111-314111223-155375333343233366487777574575768227664345432636243445434211111113647433-1---11-1-221-514-1222-335333-12111111111111111111131-242222143232333333333323333324532311-53-311111121111111111111111-1111111111111111111111211111111111111111111111----111111111111111112211111121133311---------------11111111113277775657544456222-1111111111115222224333233222222221111222-333233------------------------111---1---------------45-1 -2---32-11-12-42-3-311-2-13113223333-----1212212-11-1-2136-11-71321---222-218-522-11111-2-31-123322223--15-12-9311214512-1229A1726T4-53C21133-3431111-2--1231-4--B-2261612*-19-121-711-2-6--736124223-4 * f.24 Cytochrome c oxidase subunit I-like
[ 411] ---1--1111111111-1-1-1131--112111121222233122212113321-------121--22 332121-233311122211-13--2311111132222434121111--1112233112--111-1-132211111111--1-111212--111---2---2-1114111---------------2312122212211-11111315142113112211131133213323111111112111211111--211--1-1111-111111113211111-11111111111113-11111111111111-111111111111-1-111122-1-1111111111----11---------------------------111----11-131111111-1---22------2--1111122411---111212---1131111-----123221-12211211111111111-22121121114-1111111111111111212212112241111111122211212-----------------------------422111111-12222222111122231111112222222-122152-1123222123223231311111111-1242-3231232122112-223232234222312111--1-----1----------2122233122122212131222222222211111112----112------11112111111111111-1111111111111111111111111131111111111111111111111111-111111111111-------------43214------------11-22232131111222222223323223222---------41112122221222211111111111111113-331122---------------------------------222-11--1-11111-- 1---546-----12243534333344411111111122222221114334454433322444663232223144443245233443233242343A2231232455-5R6P7988A55235333572A4X*81O9D2433A455343434421B465465AI3B8B3223588H528A5*43465D9CV5748685889 * f.44 Ammonium transporter
[ 412] -----1-------------------------------------------------------------- 1111111122211111111-1111111111111111111111111211-111212111111111121111111111111111111211---111121--1111111-1111111111111111111111111111111111111-11111111111-----111111111-1-----1--2-1111111111111111111111111111111111111111--11111111111111111111111111111111111-11111111111-11111111111111111111111111111111111111-1111111111111111111111111111111111111-12211-22121111121112-11112111111111111111111111122222222211-11111111-1111111111111111111121111111111111111111111111111-1111111111111111111111111111111-----1112111------11------1112211--111--1111-111111-1---111111111---1111---11111111111111111111111111--111111111211111111111111111-----1--------------------------1-1-------------------------------------------------1--------------------------------------------111111----111---------------------------1111111211122111221111111111--1--111111111111-1-11111----1111111111--------1111111--11-11111111-111111111111121111211 3433657-E56355454465665565555555555555557455554455555456555555675433255466745-45366665865595454565655558973494EABAB6E8676898DI4D8J*C2CAF7676888888886AB98C9B89A47E68653549A44645667*77748HBIK5HC5675555 * a.71 ERP29 C domain-like
[ 413] 1----211------1-----------------212-1------1-----11112-1----1-----2- 3423422212222141133-321122323321222214463235312231224441222243423346353222222221113223232223241121-33333434332222222222222224333333334342233---333333333333322223333344344222111222121112332222222222222222222222222222222332222222222223223232222222222222222322322222332222222223222222232322222222222222222222222222222222222234222222222222223233322222322222323321223222222222212-222312112222232222222222222222222-221222222321311233233322122211122322222222222222222231222-1------222122221222222111113412243332222233233332243333333222333222442232332332422333333333343333333333333331112121111223222222334334232121111111112111112112222223334333233333333332333333233332-2323212-22233333333333333333-33333333333333333333333333433323333333333233333333332333333333333122211111222332421333333333333333333333333332333332323332333333232233323333333333333333322322222322211523344332223222221--------------------------23133222222223 -------------111---1---2131------11--------11221-1---111--------1----1--1-2----------------1--12-1--1------1311------------------1----------------------------2111-211---13--31---13-----2--1--7--2---- * c.5 MurCD N-terminal domain
[ 414] 11213112111111112111-1121221-3-53231112111232-3432211211111112221-11 -27--------21---111-1-112-1111121---12---121---11---2-------2-----211--1111111--1--1-111---1-----11433331--211111111--11111----11---1--32322---2-12-23311-22--12-121--22211111111-1111-----2-2--1------1----------1111--1----3-123333211143333323344433333332223223333322332113322232233323333332222222222133333333333333332223333-12211111111-1---33121---1-11--1122111--1-1----1-1--1111111111111111---------11-1----2-11-111-1122112221211112112-211111211123---------111-2-11111111111111111111111111-1--111-1121113223332222222232222222222233311111122113332212211--1512232222---33-412-1-1-11111112-21-121-534552--------------------------1--1116113-512111112112222-2-1221111---111111123211212222222222-222232222222222222232313311222212222222222212221122--2222222222221112444443333112-2---1111---1-111------12213-11112342222422322------1--343333233233333221121122211112111----1133333333--21--1--1--------------------1----------2 3322432-633355331213553777733122234123332334442333344D5332253435523313435345425434443421317212123333342454166D79856697342554C63B3Dn5177D5144A254545325514B2644647G33341631636562341812222E69I2A44563355 * d.179 Substrate-binding domain of HMG-CoA reductase
[ 415] 11111111111111111111111111111112111111111111111111111211111111111111 ------------------------------------------1--1------------------1-----------------------------------------1-1------------------------------1-------------------------1--------------------------1111111111111112221112111111--111-111121-----------------1-13-------------------------1111---1--------------------------111---1-1--12--------------21----1--11-----11--------------------------------1------1--------------------1-1--1---1-111-------------------------------------------------------------------------1----1---------------------1------1-1---1-----1--------------------------------------------1---1--------------1----------------------------------------------------------------------------------------------------11-----------------------------------------------1111---------1----------------1--------1----------11------------------------------1------------------------------------------------------------------1- 2212583-G682124548644455367554444444565675543545567565447666674322321234232443432223239663654454544345378A1484OCHADFLFIEDFHAlXJXIu*V4WPaKGGERGGNICJLIAQDClFJAAC766D8876L67CAGB53653O643458HAF7G7738CCD6 * a.160 PAP/OAS1 substrate-binding domain
[ 416] -------------------------------------------------------------------- ------11111-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----7641----12611532444331422112211122111222222245543E27432222123111-32132322-2244432143446213332212222EAC1511GacZdVPFGDBKQDucAcJ**X-WUcCHDEZCMXLBKGFENFBgIOLHOCFDB7AD6LB9FAICA1553B--245Lhf*4*D4637461 * a.37 A DNA-binding domain in eukaryotic transcription factors
[ 417] --1-------------1-------2112-11------------11111-----1121----------- 3242242233312212311-12113311111323332122111245612333456221221132243453111111113131-2111111111222---12212121-211222211112222211222122143111--1121-1-2---1----1--112-311--11111111111121-11112211213333333313333342122113332321-1354454612344343333344433433332---221-2-1----22-----1-313253433544444444444445555555555555333---533523265222122222232222422432413323112321-32243212124123111111-11112211111211322332332332-1111111-13-1111222333222112111213222222111111111122-2131111111111111111-1111111122112122221---1-------1111----1111---------1-11-21111212112-1-1-21111111111-11--22111411212111115242213432222411211112111121111111111122221122822221-2232322111132111112111-11----1----43534524446445434-454545455444545455646554213333233244342322424323314324555455555451-1----------111231114151121--232111111---12211111222-11111223111111111-1113222221314411222222222222--2133111111111121212----1-111112211121121122212122232123223 *-11----5211--1234223233232331111212122222252411111-31121212221-3-1-12121-1131112111-22121-13-2-2121112112-22231123-13122-21341516C2-323-21-4112112--1221111-1-2491311--1--11223---1---2-11142331232231 * c.121 Ribose/Galactose isomerase RpiB/AlsB
[ 418] ---------------------------1---------------------------------------- 1122222344321222222-22222222222232222322222222322222222222112212232322211111111111311211111211111112222232222111111111-1111122222222222222321114144453333333333333343433333333333323332221111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111-111111111111111111111111322222232222113321211-21111111111111111111111111222222222222233333233333222222222221222222233322333333333333222221222232222222222223222222211-111111111111111111111111111222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211111112122222322211222222222222222222222222222222222222222222222222222222112222211111122221222222222122-22222222222222222222222222222222222222222222222222221222222222222112211111222222222111111111111111222222222222222222222222223221111111112222222222222222222222223222221214433331111111121111111-111111111111111111111111111112212 32--112-722-2221222222212122222222221212-222222222222222222222122222-222232221222222223332322122--11132335-2F143535333312133542616G3-648332332341231226225453331--22232222542125442H21233B8792A37922227 * d.45 ClpS-like
[ 419] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------1----------------------------------------------------------------------------------1FVRMwNbWLHPTTW*sOyR**m9vZ*JNPLaPasfEZPJF*EIwNkMWa7Jr-7999---p--6--------------1---------- * g.23 TB module/8-cys domain
[ 420] 11323251222222214133333321121511434446664464234511567754353852123-11 33513-2-------13122-21--44212221333313323343-1--1-----------22322224321--------3322555532221111-1---211122311--------------1332433124436556555532244333211221111112212332311111111111111111111-1-1111111111111111-----111111----------1--11-------111-----------------------------------------------------------------------------2--1211111111-13-------1-1--2--5566211-2-42--221--36-111111111746572114963611111111111-11111111111111112222222245111123444411122222222533127251111111111111111111111111111111113-11111111111111111115222212144128511211341111427121153121111111111113357134-62336545561847677818556514184333222222222222222233746553412------111111-11111112111211--241311111132334215554544455-5455544555545555555222311136666666666646465255564451-31111111111111111111122234-11-111121---------11111111114-1121111111211-2112111111112--------------12222222221111116-222222------------------------------------121111-11-4621 ------3--1-1421111111121112112111111211111132233112122112211111111---1-13111-----11121--112111291112112112-22252432432131232D72428O4-4552212322222332242131314323232282545213351111----112335125112312- * e.18 HydB/Nqo4-like
[ 421] 1---------------1-----1-1--1-11-1--------1---------1----------1----- --2-5------------------------------------1-1--1---1-111-----1--11-1221--------------1---3342--23-------1311-4------------------111--2--122-21111-2151--3--------------5386---------------------------------11-1-----1-----1-----------12--------------------2--1--1--------------------------------1--------------------------------------1111-1-1---------1----1---1------------1---11122------15IJD25153678------------11911B11-7--21127427851114-----23-22--------------1-1-----------------------------------1--1--------------1111-------21------1-----1--21111--8---1------------113---52-----5-----123----111-114-1--------1---1----------1--------11------1------1------------1--1------2---11--------------------------------------1-1-------------------------11111111111---------------3-----------------111-11--1-----1-1---1-1-1---1-----------232-------11211111121111111--1-22------2----------------------------------------111-1-- ---131--1-1--1-132263315342-11--------------112333559634242433-14-11--212-1------11-221-135336361311-11221-363*ISJHUVCCEDDGAKPDdA**Y-hPSEFDFODEFFDGGFFJDCgFKGJFKOLFjIR7AIB927E8--2-3--1-1-1221---1-1--- * c.17 Caspase-like
[ 422] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---1-----21------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------- ------2-------------------------------------------------------------------------------------------------------oTkZacaMAJKGWJoVGTE**W-XRdGIGFPHJiSBLOOTSJEdNLKeNBE6GzgrBx7Dg**N--11-----2--------------- * g.8 BPTI-like
[ 423] 11111-21111111112123433-32223342-21111131211132311122311111111111-21 111-11-----11-11111-11111211111111112111-21-1--11----1----11--1-111122-1222111----1--1112111122211-1221211111-------111111121121111112121132---212232221211212111--12-2321111-111-2---111--11212111111111111111212121111111111111111111112222222222222211111121-11-111111111111111-1112222333111222222222222222122222222133222333111111111111111111111111111--11111211-11111211211--111----------1-1-11-11111-----------1-------211-1---111-111-----3----------1------------------------11--1-11111111111------1---211111231111111111-111111116-13111111111-11-1111---1--11---1----------11--3-11222211112121-2111-------1-----11111--------------1111---2-------1111-1-1111-1--1--1-1-11211-111--11---1111111111-1111111111111111111---11-11----------------1-11---1-1111111111111--1-1111112121---11111111111111111111111-111---1----1---------1----1---1-111------111111--1-----------11222322---1--1-111-------------1-1-------------1-1-1--111 34127541E55644833456656556577355575756564354545554434423323333223454135315246145566641555554364966543954341554A7A67DB7966776DD4K8X*C1HAO7748B489B75567B63C5D9974B768462647I58252244V75525899B4981245453 * a.289 Sec63 N-terminal domain-like
[ 424] ------1----------2--1------------1---------1--23--------2-1-1---1--- 132-211111112121111-11112-11111111111111122221212121121111--11242123331----1--212-21-11144551311---11122211232222222222333312221212222433344---222432322-111--1---121-1211------------12111222111111111111211111211111111121-112111121111111111111221111119111-2112-111111111111---1111111111111111111111111111111111111113111111121113111111121222111544213221432333232211242212311122---11------2--1-------11111111111---1--1--1212111111211111----11---------11111111-----212--------------------------------1------------1---------1111--------------22111111211--31---1--------11211114351121121111153442332311113334---1---1------------11111--121211123-2------1------------1--1-1211111111111111111111111-1111111111111111112222221111111111111111111211111111-11111111111111112222211111211-111111111111111--1----1----11------------------------1111111111211111111111111131211211111112222222232211111---1111111111111211133333242222231 5656323-9131222446224224345223222224423222232233333223223232232555552464644442544445442223724442444534345534526GJEKB57574767796E9Q*8-ICC7558C87A13773265568B66448L95423624557323443O22244IDIK3EB3211225 * c.89 Phosphofructokinase
[ 425] -----------------------2-----------------------2--1-1--------------- ------------------------------------------------1------------------11---111------1--------21-------------1---------------------1-1------22-------1-------------------------------------------------------1--11--1------1-------------------------------------------------11----------------------------------------------------------1---------------------------------1------------2-------------------11--1--------------1---------------1---------------------------------------------------------------1---1-----------------------------------1---------------------1-----------1-------------------------------------1----------1-----------------------------------------------------------------------------------------------------------------------------------------------------12-1--------------------------------------------------------------1-----11--------------------------------------------------------------------------1-- 111144A-511Q11323444444433544354533324445335543445454444464333221111-21221111-1111112112124134143232222142-812KNZLMWNIFIIMLHhdFjH**Y1hOiIJHJYGGSJFHJHGSJFXFKKFH7AK9LIH6HAHE7876-1-1U2322-89FL3A6339HHC3 * a.65 Annexin
[ 426] -------------------------------------------------1------------------ ---------------------------------------------------------------------1--------------------------------------------------------------1---------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------11-------------------1-----------------------------------------1------------------------1------------------------------------------------------------------11---------------4---2---------------------------2-------2---------------------------------------------------------1-4----12--41-4---------------------------------------------------------------------------------------------------------------2-2-----------------------------------------------------------1--1---------------------2----------------1---------------------------------------- -----18----------------------------------------------------------------------------------------------------1--nRcomzSPKQLFHIcgUaT**c5mJrLQGOWUGUDIIJMSSLLmQROR*GIUWbeIENPEdEAS5-----------------1------ * b.120 Tp47 lipoprotein, N-terminal domain
[ 427] -----1-------1--11-----132232222434222222222225223787411-2222-221231 121-422422232231211-12111111111121113222322252221111332231221224323676211111112122411111111112111--1211112111---------------11123111222322111112344583334555233232334556631221222211224441111-24333333333333333344222333276413111111115211111111111111-11111111111111111111112111111111111111111111111111111111111111111211111111124343222222212232331222214113128466867444373332-111-222112222246954K535776522232122222-76966979262125423433223453131341454441111111111133-218411111111111111111111111111111-222311211257737532111559823221144C343211221111113111211112111111111111124A31111111111211111121111212111121131111111111111222222211111111212141131114214111211212112111-1511111-11111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111111111111111111311111111111111111111112211111112111111111111113122131111111111111111111111111111111111111111111111111-1---11---1--------1-------1211111111-3-1 --11--2----3111-11-1111-1-11-1111---1------111-211----111---1-1-------1---------------------1----------11---111885B453221432551938W4252A241332332-33215225226461-1211118122142-2364N344523223-2-23-1--1 * b.41 PRC-barrel domain
[ 428] -----1-------------------------------------11111-------------1----1- 111----1---1-111111-11112-1111121111-111-1111-1-1111111--1--11--2-1-1-1---------------------------------1-1--------------------------1---------1-11-------------------113-------------121---------------------------------------------11-----------------------------------1-------------------------------------------------------1-------------1-111------------------1-----------1-2-----------111-1----------------1-------1---1----1111111------1-------------------1---------------------------------------------------1----------------------------1----1-------------------------------------11-----------1111-221--------------------------------1------11111--1111-1--111----1---------------------------------------------------------------------------------------------11-----------2--------------1--------------------1------------------------------------------------------------------------------------------------------------ ----11--------1-11--1------111122112-111-11-1----23212---21111----------------------------211---111--------21-*d**Z*WIFGJJHIzlF*O**a3rR*FOLEYGJNP5LMDCUDD*IDBBH96--A351--1---51---------12---2-1----1-1 * d.321 STIV B116-like
[ 429] --------1111111---1------------------------------------------------- 5NG--------------------------------------------------------------------------------2321378D9-523---2545344857--------------122232222364-----------22222133--------31151111-------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------2-54-6352-111176765785B84BC22222222223-12211-2334513332222123324364911222222217777777763353252111-------1111111-111-1111-1115653333333345563744443353444432B69454323433665335335335877756441111111334449E4232323623663133344555667A4OF452243243222124221222265-22BB64244A937526676665656444689437--13334------32252322343243322-222423523433322222233388446222221222222222254522223215333333333332228-111111115352333311212222322244544663427B6666688A4343459A91--1-----234543333345344GJ9AAA999B66661141884444-----------------------------------------1-1--9K25 ---------------------------------------------------------------------------------11----------1------------------1---------------------------------------------1----1-------1----------------3-----3---- * d.212 TolA/TonB C-terminal domain
[ 430] -------------------------------------111111-----------------------1- 21--2111111-------------------------------11--11-11-111112----111-1111-1111111-------1-1------------1--------------------------------1---------1-3-------------------1--3-------------22111--1-2-21212222-222222-111--222231C----11-1-IO---------------------1-------------11--------------------------------------1--------------2F711---------1B-11-1112-X11K--BG--NHJB3W-E1271I---------------------------------------------1--2--1---1--11-------------------------------1--1111111111111111111111111-------2--11111111111111111111111111111111111111111111111121111---111111111-1--11----1-------------1---12----12-----------------1--1------11221---1-1112222222222222222322------1111111111121-2111211122-122211121211111211222311111111111111111111111111111--211111111111---1-------------1111111-2222111111111-----1-11111111111111111----------11121111112222--------------------------------11---------------------------------------- -111331-311-33433344333333333443333323133332443334333533344344334222-32243322232244343222331323323243237671252DDABCFFAB9B8CAgS7M7m*J4OIRAAA8E8CFE7D86AK98NACA9B66BAB776H4367C971222D2224285273742332332 * d.82 N domain of copper amine oxidase-like
[ 431] 11--------------1----------------------------111----------------1-11 2232221222232332222-22222322222222222433222322112222322222112322333333111111112112221111211111112--121313213311111112222222122222222132111111112211121112222222222112211122422122522223221111112233333435335333532332333324322222222232122222222222222222322222222222222222222111111111111111122111111111111111111111111211111111111222222223322212222232222111111122222312211111112212211211111123232222222222222222221-33633426231122242243224411111112222212211111111111122211112222211222222222222222222211111133422333333222223233122222323334423222231111212113131111411111111122113321112111111111333221222222225111211111112411111111121122112212132111221111111112111111321-1221111111111222222222222222-222222222222222222222222352222222222222222122222222222222222222221141222222332111121111111111111112222221221123333244322222123312212122211111111111111131222223211111111122112222222222211----1-111-111---11111111111111111112312 22--1---2----21-1------111-11--1--------------11--23-311-------11---111111-111-111111-1111-111111112-1211-2-11E444441554534476294Mo6-B6B333182564345335227434234432523-6322135512217211124223-321242322 * b.46 FMT C-terminal domain-like
[ 432] ----------------------------------1-------------------------------11 9OV3I--1111-1-C9844-49--6F434446CBCBD9JK18498G15333-767421--8AA2A6MHJH2---------1-1-------1--111---5C689O7H1E----------------1-112--22-23323---J45241221--1121112112111311-1-1---1-1--D6B221--3-BGFIFIKIL5JKKKIJADB939MJO244C853111111CK21111111111111111-221---------------11----11-1-1----1111-1-111------------------2-----------1----------1-----------2--91---12-------------1-D-95112-----233422221211111111111111-11211121334-511133334511-132323211111-2--------1---1-4-------------------------------2133--32123665441222255423333234333343-2332221223353423421--12--------113111-22---1-11-21--212---1--222224-11-----------3-------11--111321-323-221132221112222-2--2-1---1--1-------2---21------------------------------1111------111111111111112------------------------2----------14-1-------------1-------2---132212133331-112111---------11--1----------1113132111------1122--11--------1---------1----------------------------1-4 ----1-1-321-1114136232325422222332421111-111112224656644432322--2-----1-1-------------11223212233121-12211-14-41--1-31--112-41--2141-123--2-1-111--11111-211211111213---111-222113-13111-1--14111155242 * a.213 DinB/YfiT-like putative metalloenzymes
[ 433] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------14331312-1-6213-22345544222121---21-1---211113212242-2-13-21211-------------------------------2-1--------1-------------------------------------------------------------------------1-------------------------------------------------------- ----------------------1------11-1--1-------------1------------------------------------------------------------21-6-1eR**rZsXPStQbO*5-rOBHzfmYX4*EhXEq*f**Y**e2*------------------1--------------------- * d.323 Phage tail protein-like
[ 434] ---------------------11-1--1----------------11---2111--------111--11 2222321222222223311-12112311111222223273111212111221312131221221224213211111112224212111222212222--111211222211111112211111222212222122333332223232423332322332232234233441311-11311112112212112111111111111111112221211122231212222221211111111111111111111212111111112211221113211111111111111111111111111111111111111111111111122111111111121221112222221111321-112113112122321112332224121112222322222223222122222221222232221112211111311111222111111111111222222222222212111122111111111111111111112122111221111111111111111111211111111222111-133231112432321223232212111111121231222121212121111122222111256648423222222222221211111112211133111111131313222222322223233223--12222--1---11231122222222222-2223222322222222222111216822122222222222222322112322-111111111111--12111111111221312221111222121112222212112233223222432222222222222212211423222222232211212112231111122122221111111111221-1--1-11211221112-221111122122222222311 -----13-753-2132322323332122222124332222312322523431321142242521233222322253324421112122415333232221131333126232543222135322263232E2-224223222222-22221113212351-125431431122333333e4445468962681241235 * e.39 YebC-like
[ 435] -------------------------------------------------------------------- 1111111111111121111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111112111111111111111111111111411111111111111111111111111111111111111111111111111111111111111111111111111111-1111111411111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111211111111111111111112111111111111111111121111111111111111111111111111111111111111121111111111122221112222222211111111111111111111111111111111111111111113333112222111111221111111111213311111111211211121111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111121111111111111111111111111111111111111111111-11111111111111111111111123111111121111111112111111111111111111111111111111111111111111111111111111111111111111111113221222212221111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 2211543-A32-22312413112121222311121221111111113223346521311214412325123322216-334212222112432243533111274C-2C6MEDCA895887676JG5G4V*E1GAH65769667877974867J4A68924F78842A3593AC63332H222236EQN3MD3724223 * a.144 PABP domain-like
[ 436] 33231333333333332211211343333433323443333234234544433422211111--2-34 232-233333322222222-2111232222221444322222222123122212212111223222332233222222-1223123331111-1112--111112333222212221111111222322222232222223322212212222222211121222311121111111111112112222222222222222222222222222222222222222222222312222222222222212222222122132222222222222221111111111111111111111111111111111111111111111132143222222222221222111224122123444232223223333111311111222112223222222223222222222222-233223222321222322322233222332332222222333333332231222222111112111122221222222221111222222233333233333333333333333233333333333333343333332233333333333333333333322322312222322322421222212232413422322222212111111111222332211-1321-1111111111111111111111--22333--------------------------------------------------------------------------------------------133323222232212---------------222222233312222221112211221113333333332111111111111111121111111111121213333331111111121-----1-111-11111111111111122222222222221 11--11--1-1-11222222222221222123322232222222222122223223232233122222212222122122211111-2123223242221232222-1-2323112122111113-1313A2-423111221111-121-211211231-23-1111211---211122D222111114232121322- * a.182 GatB/YqeY motif
[ 437] 11-----1--------1-11111-------11-------------------------1--1---1--- 2332422222212131123-22112321212223333343431-552322214442241133534344453233322222321112211112-111--------1----11111111111111-111111111-132222111311111111111111111111112222111111111111---11--2-223333333343333332111233332113-22222222322222222222222221222222242233232224422222233333333333332222222222222222222223222234322233331431333332342221622-24212122233214413221121222113211-2222-----1-3112-12212222222222222-11311613-31-333344443344321111121-11-122222222212221213-----------------------------11121234424546565344444445555535554455511444433334353322232223642222222111322211-212233222313332323224444211123322111111111111111-2111114521523223422222123222232332531-1111311-11143122432333222222-32222222123222222224342223344444444444444442223221211222222222222-1111211223221382333323121121-11222222122223366764543544443333111111111123362222255333222222222211111112111122--------21---1---1------------------1111111111-21- 11-1123-A521121--2-1--1----------1-1-------111--------1--11----11----1--21111-11111111212121-1141111--1222-243411221111111122121--1--111111-1112122-211-2111122--1--31--1----2-13124---3-3224-221332222 * d.116 YbaK/ProRS associated domain
[ 438] 11121111111111111111111111111111111111111111111211111111111111221111 2111111111111111111-1111121111112212111111121111111111111111111111211111111111111211111111111111111111111111111111111111111111111111111111111112121111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111112111111111111111112111111111112121121111111111111111-11111111111111121111111111111111112111122222222121111111111111111111111111111111111111121111111121111111111111111111112111111111111111111111121111111111111111111111111111111111111111211111111111111111111111222231211111111121111111111111111111111111111-1111111111121111112222222122-22222222222222222222221132122222222223323221211111211111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111221221111111111111111111111111111111111111111-111111111111111111111111111111121 45222251F542333434433333443664333333344443343333333344333253434444442444544555554344535555623545333333356514B2633353533333A3CH3849e6-65H4343B44891444233362332545435432C55735444775p3254598DC3A64353331 * e.24 Ribosomal protein L1
[ 439] ------------------------3113-1-1------211-11--12--522--------------2 --3-1---------1--11-1---51111111----12--1-1-4-1--1112-------22---222121---------1-1--211-1-----------------21-------------------1--1-2-23344---7324344411133------25313461------------111------31222225253422552153231232241E1451-----B91--------------1-----------1---------------------1-----------------------------------------6739222-12253731552---933--5--5234461161111--2---114-----------11--1-1--23--------------2-11-1-2--2--122221222111-11--4-44211---------22--3-1-----------------------------1--1--211115334374122166262222225564244--4342131232181-232--217A11-----3-147825412243-842161BBDG6BB47225-25-32111-1111-2---------26411--F6246462543DIEFEA77CAAF8878F9A----31C------42163211222112211-211111111122111111-212441-1232222222221212221111111--233333223333--11---------1-E28---111-1111-------------123JHCHFGEGGDBABEIGF---------4A99GGFFFFBC7GF--23432323------85AA44651--d-EI192------------------------------4------1-- 1---1---1-----1---11-------------2-1-------------1-------------1----1-----111--1---------12--12------1--1----411----111--------1-1411111--1---111----12--1-3-1211---11---2--231--------1-2--2-1---1---- * a.154 Variable surface antigen VlsE
[ 440] -----------------------11------------------------1--1--------------- -2112---------31111-13--12111111644413--2--151-45---221114----3-1132541----------42----15212-311---121133-2-2------------------11-1-22-12212---5-5322223113322222323244464232221221222-----113-224444463424347732111224472222254211221642--------------11-112-1-1------22-----1-21211111111112112222222222211113112112222111111111-542233333332425411-1113-111122-111-411-----11---13-14223-----466677643555544554444555-664565545721666668568755661215444356334------------1433------------1---122---22------32212-11--2332322333322213333243622111--1-131-11141-133231---6--1--2-211-222323-2-1622211133-2-3131---1-8A141212--1-----2--------1-11113322-3111222222222422222233225--1-1--------43333343332332243-3336332334324333332322333244444444555544444644222332-544464444477--33-----22224-2213333532453433333333343111212221-214123431111111111111-5435222223353443334334451111--812211111111111122--------------------------2-----------3- ----31--1-1-------1--------1------23-1-----11-1--1---1-11-111-------------------1----1----1---11---------11--2A566674433223334143AN5-235-33231454-33213133362344662352122152-2----2--1---2131-----1---- * d.65 Hedgehog/DD-peptidase
[ 441] 1112-1221111112212332221111-11111111111111111122111112111111111121-1 1221311111111111111-1111111111111111111111111113111111111111121221221111111111232221122233332333222222222222211111111111111211111111111211222222311211111111111111111111111111111111113221122123222222222222222243332222234332222332224222222222222222222222224222231112233333232213333333333422333333333333333333333333433222333322332333344424225332232222223222233222222222232122222111111111111111111111111111111111-1111111112112111122223111111111111111111111111111111211111111111111111111111111111111111111111122222222222222222222222222222222322111211121222222232111112122222112122111111111122222222221222222-----111111--------------223322222222222222222222222222222-2222222122223222322221222222-22222222222222222223232222233233333332333332222221221222222222222222222222222222322222322222222222222222211122333322222222222222222222222222222222222222222222222222222131211111111112112212121--1--111-----111----21121222221113 1111111-31111111222111122311111111111111--1111111211211111111111111111111111111111111311113121111111211111111244332282221242262123E212232222522211221132362222P13523211123322141121911111212212111-1111 * b.153 PheT/TilS domain
[ 442] 3314331122222222426455652122-213223552223222221332222667756671113222 ---1-----------11-------------------1---1111--------1--------1---1----1-------21221-----1111-111---11111111-----------------11--1--1-11111-----21121-111--11-1--1-11-1--111111--11-11----33---11111111111111111111111111111111--111111111111111111111111111111111111111111111111---1-11111111111111111111111111111111111111111111111111---------1111111111-111111--------21-111211-1-----------------------------------1--------1------------1--------------------------1------------------------------------------11--111111--111122111111111111-111111111111121111-1212111-1111111---22111111-11-------1121112212222212-2--------------------1--1--222122221222323222222232222322--1-2-----11122322222222221222-2222222222222222222222222222222222222222222222222322-222222222222211111111111111222222222221222222111-111111223333322233333322211111111122221222222222222111111111111--1---11----------111114-1-111-111---11111111111-112-211-1-- 221-633-A42112232214322321222422332222323333445246444644342334221113212223132-4222222232112224573333--163712N4987776BAACBB8B786A7Ly8-A6B5D6B97799669D976A5C67462A553427422634521443R34123EDLR23C4362546 * d.308 THUMP domain
[ 443] --------------------------------1----------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1--------68879993--DGDDC9FCCBF6566666766665799---9996----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1-------1--------------------1----1--111-1----1----------------------------------------------------------------FIG9lSPSQRWYU*dRpY**u-viwTRSUYUaiaLZYSPZTNVOUI6H---1--------------1-41-------1---------- * d.9 IL8-like
[ 444] -----212111111121------------------11111111-------1-1-11111111------ -------------------------------------------1-1--------------33-----2---------------11112------------1--1--------------------1--------1---------1--------11221-1111---------11----1--1---1--11-111222223121223332221111331111-111------11111111111111111---1------------------------111--------------------------------------------1---11111--1-1---11-----11-----21111211--1112111---1-----------------------2-12112221----1--1-----------1-------1----1--------11111111-1111-----------------------------------1------------------------------------------------1---------1--------------1-----------------------1-------------1----1-1--11-----1-11----1-----11111111111111111111---------------111-----1-1-1---------1----11------------1-----------------1--------1---------------------------------------------------------1122---1------1-----------------1-11-----------------------1111-1-------------1----------111--1------1111111222---- 11--957-733C111222111212121211212111111111111122112113331121112111111111112-2-1111111111122121121121111322-26M*HKGKJSCEC9HJEfa6UA**T8VFs9JEDUAGQD8JC8CR84mGIEFF9IqCJG96G84HBH991142R-22-174D81532222323 * d.156 S-adenosylmethionine decarboxylase
[ 445] 1111-11111111111111111233222222411122222222222322233212221211111--11 2121221111112122222-42112222222222222222122222222332222323--2221322232111111111---221311111111---11-112322121-------111-----21121132122212113232122422222222222232222223621222111212212372222-222444444531344444224422434222222222222233122212222222222322221-1-22-----1111221---1-222---111122222222222222-------------2114411111221211111111211312211112121-22122224322112222221-22132113-----113222113221211111111112-22122123322-2332222222222111333223223221111111111111221-----------------------------11212111111233332232332222333323322344212444322422233222222111211111111111222214111211111111111111211222222222111-11112-11-1111112111211223211232122222323222222233233--1122211-11133332333333333333-3333333333333333333333332223332333343323233333333332-32133442333311-3-----122222422111112-11111-11222222311121222223222223232221--11111-23333222223333311113111111111221-221122--------2-1----1-111211111111111111111211212221312 ----1-1---2-11111111121122111321122112212111112222223322122221122111-1111131233211121111112112112122132211-121312241-311111-24141BL3-317-1-11122-1111-2--612113--11512-----253-321191112241261433123221 * c.27 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
[ 446] 11-1--1111111111-11211211--11211111111112111111111211111-----2--1-11 2131211222211131111-121114111111211133332113242-211123111111121-24423211111111-11-111111111112---11-211311212--------------111121111111111111111111111111111111111111121111111111111112111111-111111111111111111211111111122111111111122111111111111111111121--------------------1-111-------11111111111111-------------111222111-14-24111111111121112---2-1--1211122111111111111--12136444-33-3536771134543333333333226-33433537951-6554536666875522234523444352122222251122111--------11-------------------2226222552757767563333558B333334558775512552326336563A9221132321334333311131112211111111111-1111113111111-3111111111112111111111111111222244324-3423533432344443333433-1-121111111133213314222422222-2232222222233223222222211133232323333323222322222221-22222222222211-------111122446111111-1111111155555331115233233344333355333121212212121312222222134223333333322221111111111-----1--------------------------------1--1-111131- ------1-----1-134224464575522222222222222222232334344634333222212111111111111-1131112111123242222222122222--4---2-1-1----1-1-1--------------1-----1-1----31---1----1-1--1--1-1-1111I11111D1342241232442 * d.334 IlvD/EDD N-terminal domain-like
[ 447] ------------------------1---111--------------1---1111-----1--111--11 2222312322312121111-1111111-11111121222312422-223112123222113322321324311111111112111221554422222112223223323211111132222222222232222222223311121221222221113112232323223322212222212222222-1113222222222222222222333222222111112-----1111111111111111111111111----211-1111--112-12111111-1111--11111111111-------1-----11----1111-3133222222222221111111223-12211144-1-131-1111-2121-33332222243333333233333333333333331443453433432233333322233323332223233322333333333333332311111111-1112222222222222111113322122223222222212223332222223233224333333222222222222221232221111111222222123331111111112-1-211--11121245-211111111111111111112212222222222211222222222322222222222--13222-1----22222212222222222-2222222222222222222222221122322222222222222222222221-222222222222--12111111111222321111221111-111122222122233222222323222222443122212212222222222222222223232222211212222332222222222222-211112-222222222212222222221221213221133 11--111131----1------------1------2-------------1111--11--------1--1--1----------------1-----1-3-------121-25242233112323232441437X6-34632222443322422521324334--61514-1---21412222R232225115-31223112- * d.173 Methionine synthase activation domain-like
[ 448] ---1--2122222222--1-----------1----22-1111-------11111-21----------- --1-2--1------32222-42112322222233332233-32221---11---1-----111-3122121--------1--1--1--------------2----12---------1111111------1---2-2111-1111-21311111222--1--121132123------------11111---82211111211-11121111--22111112----------13------------------------------------------------------------------------------------------1-----------1-1--21-221--3-----423-3-2---1-1-11-----12221-----223221113322411111111112-22322322142-31143243232134-1-33311122231-111111--1-1323-----------------------------1-1---222231222223333222433233224342323--22211212122-32-1------------------112----1-2-2111--1------1-----53-12--------------------11-1------1311-11-----------------11--11233------22221222223233322-2222333222232332222233231111111111111111111222222222-111111111111---------121312233---------------2211211---1211-11231-1221-333122222222----22222222222--------------1-1-------------------------1--1------------------------11-- -1--445-8521334356267556585221334253645443425344677B795758522243242222223232222222222211124355473221242222-7M4IBD79966546454B9783Hf5-9692465534457433564785665842246978A52323734CE2B33367Efjp6RD5524335 * d.269 Gamma-glutamyl cyclotransferase-like
[ 449] ---------------------------11--------------------------------------- 1111312222222211112-11111111111111111211111121111221122112111111212222211112122111211111111111111--111111111111111111111111111111111111111111-11111111111111111211111111111111111111111111111112222222222222222222222222222231112222221211111111111111122212122122122222222222222222222221111122222222222221111111111111222222222212112111111111112331111111111111111111-11111111111112111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111-1111111111111111111111111111-111111111111111111121111111111112111111111211111111111111111111111111222221111111111111-11111-1111111111111111121111121111111111111111111111111111111111111111111111111111111111111111121111111-111111111111111111111111111111111 ---1143-----33521111211212111111112111111111111211212122111111211111-11-11111-111111216444B31855112243267A22A2A89AIB97442666FD6H4Ha6486955446676665725853G8665718G5A5328378-2234346c77555C63M1W5782333B * a.59 PAH2 domain
[ 450] 11323241222222214113333321111411434456764463244511577554353852123-11 33512-1-------13122-21--44222222433213323343-1--1-----------22222224341--------332145442111111--1---21--22211--------------1322333123434446555532335433211221111112312332211111111211111111111-1-1111111111112111---1-211111----------11------------------------------------------------------------------------------------------1-11211111111-13-------1-1--2--3477211-1-32--211--36-111111111535351114753511111111111-11111111111121114222212244111113444411122222222633126241111111111111111111111111111111112-11111111111122221113323322134116411111331111326111143111211111111113256134-62336545561847877818556514184333244444323222222233746663311------111111-11111112111111--231311111132344215554544455-5555544555545555455222311135554555555545444254444551-31111111111111111111122224-11-111121---------11111111113-1111111111111-1112111111112--------------11111112111111115-222222--------1---------------------------121111-11-4621 ----111-211-11221211132234122121222222221222111111233211223111111----11-111------11111---12111112111211112-1-33211111-----1-22-2-4J1-321----3--2------1--2-1121111211134212112111112---2124-61131235251 * e.19 HydA/Nqo6-like
[ 451] 21-----344444411-122-1-62--2-111----------1----1----1--------123-1-- -1-291-2221---45433-38118633333577794988332222122--22121----86417186963-------1--1222112-----1------------2-1-----------------1---1----23354---5-3224222--1131111211112231121111111111---1111-1-111111111112111122111111212-31---111--31--------------------22--11--11122--113-2-111--111------------------1----11-------11---111---1-1-------1-11111----2-1--223--121-1-11-------1----3224-----1-211--13113211111111112---3-----122-1111--11--21311222122322124--------1---1122-------------------------------1112-22211----11-111---1111111---2444-13321--121-13-21-121--12----------111-A18----1-------1-------222237---------------------------23332231422123333323623324456255--11121------22222213333333333-3333433333333333333224221122333323222332333432222232-222222222222--1211111111122432111-1-1----111122332232233155554353544565333---------123333333322455111111111111111-12-------------------------------------------3----------1- ----231-1--14351111221163512211111212232222111241211-221211111111--2-2--11111111-22212---21312111111222534-89-A7655898545775EB599KzC2D9G3344A589636644844946734B854A53245A67546-12-1-1-113312111--5445- * d.106 SCP-like
[ 452] 22222222222222221222211222222222222222222222222222222222222322222222 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111121111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111211111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111211111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111121111111-111111111111111111111111111111111 5422443-F552332323333343233332333333232323354432233233333322222232231334233243223444335553532343433331387C237493842354475364BI3F27O8-64A5243933654356233643244447333433343444334444a54445I89C3854434334 * c.12 Ribosomal proteins L15p and L18e
[ 453] --------------------------------------------------1----------------- --1-------------------11------------------1---------------11---------------111--------------------------------------1-------------1--------2-------------------------------------------------------------1----------------------------1---------------------------------------1---------------11-------------------------------------1----------------------------------------------------------------1--------------------------------------------------------1------------------------------------------------------------------------------------------------2-----------------------1----------------------2---------------------------------------------------------------1-----------------------------------------------------111-------------------------------------------------------------------------1-----------------------------3---------------11111----------------1-1------------------------------------------------------------ 2122CD5-21-1445666655556567556554545565555555577557887666766764444444467634775884444466665C566794445556D98-A14BORIWKICBCBDDBdTBUC**Q5UJdBBCAKCCE87DCC9FCAYCCDEB5BG776C885494C773524Z4452CB79B6F6-122331 * d.338 Oxysterol-binding protein-like
[ 454] --1---------------1-----22222222111---1111111111-1111-------------12 2213121133112222222-23112222222123243222222224221321111211112232322111211111111232211111111111112--26354332441111111111111133111A3112332222111112745233211112222214423342212222222122211111112113545553353246444222223464111322233333332122222222222212322223232222322243222222222222222222222222222222222222222222222222222222222144233333543232224422223113231211553212221111111313137444------14342135632A2212121-111-1--2-12112811---122322-233518--1111---111111111-113-1-1111---------1132115211111111-1866711----222223311112222321222222222212---1------112-1111112213433133-11222222321212422221332221312333352211111111111111111111121112--1111212111-1111111111131111211----12-------1211-222222222222-2222222222222222223222111112222222222122222122222221-111111111111---5212222D5412413-------------------------2111111111111112111221-21222111-111111311122122322111-------211111111111111111111-1-111111111111211111112111111111713 --11--1-11111111111111111111111111111111111111-C11112-11-111212-11111-11111-11111111-11111-11-11111--11-12-17-831311-11---1-11-21574---21---2111--1---1--21--1D1211112-111-111125I2B345223526143-211--- * d.226 GIY-YIG endonuclease
[ 455] --11111--------113111123-----1--21111112221222222211131211222--11--1 ---13-11----1-11111-11--1111111111111111--11--------2-------11211222211-------1--111----11---1-1--------2-12----------------2--12111111133-1111--23222321122111111-3221143--1---------1111111--11-----1---------1222-1--1-2211--11111122---------------11111-------------11---------------------------------------------1---------112111111111-1111111--1111---1112--3-2-11-11111-1111-122------121111112222211111111111-32222222-1--2111112111111111-111113211122222222211-2213--------1--1-----------------1-112-----11111111111122111111111221111--1111111-11112112111111----11--22-111-22213142133321112311311-----1-1-----------11-------1111111--21211-11111111-1111111211132---111-------2---2-1-----1-2--1----1---2--1-------111--12-1111111111111111--------1-1111-1111------2-----1---11211-----------------1-------1211112111121111111----------122111111121111-221221111111--1-112222--------2----------------------------11112-213121- 1222213-532-3342254233234242222123445444423412326355451344233222321422213223224223333242447425355543334354-2869EDLDEA7564475LQ3E7n*9-DCI4667B976439775E55G9B86745C53444AA6G79333494V45523C8CE2B52446772 * e.50 AF1104-like
[ 456] ------------------------1--------------------------------1-1-------- -----------1-11------------------------------------------------------------------------------------------3-----------------------------------------------------1-----------------------1----1------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------11111----------------------------------------111-111-------1------1---------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------1---11----1--------------------------------------1------1111111111-1111111121111111111-------------------------111--11-----------------------------------------------11--11-----------1------------------------------------------1------------------------------------------------------------------ -2------1----1---1--1--1-12-------1--121---2--31-1--1-----2----11111-1111-111-11111111111----11-1-1--1--------ZZicmYLMBIIMAN*eCvO**v8*TH7KLHYMLl74RUGJU34sQRBEJFMV4662395337B1----11-1--1------112-1-1- * e.69 Poly(A) polymerase catalytic subunit-like
[ 457] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------1-------------------------------------*hcVORWPMRJSVQeXOPL**X1pS*KSNNaOSZV6TGNJRIHrPkRUN7AE635G9FKEBBHn6-------------1---------- * g.28 Thyroglobulin type-1 domain
[ 458] -------------------------------------------------------------------- 1-12-11111111-11111-111111111111111111--32231-1--11--1111---11------2--111111111112111111111-1--11-1---11--211111111111111112222222212211112111-17334654123325333434342143422434324344323221112211111111111111111-11111111111111111111231---------------111111-----1-1-11111111111-111111111111111111111111----------1--1--111---112434222223223213113222221-24222232222122-21111111--4---2-------22331---2-3--------1-1-241-11221111-----1222-1--11-211--2--11---------311-131111111111111111111111111111111111111----121111211111332311111112212121131113111122311111121111111111122221111-11-1211-----211111222-11123222112222222222222222222233---111313111111111111111111111111--2111-11---1111111111-111111-111112111111111111111111111111111111111111111111111111111111111111-11-----111121111111111112-111111111111111211113111111111211111211111111111111111111111111111111111111-11----111111-21-146B3--1-----------------11121111111211- 3311353-F66-11211221-1222222222222222222222211222222331222222231422312333313323433332121232212222222221344-26274333455454214873649c61676314342343233535434333243432255533552532357A*A9A97GALI2GD3322227 * a.269 FtsH protease domain-like
[ 459] 221-2------------2-2--115334J7251114P71111123132122116HCE6M6C1111-11 ---242--11----12144-42442444444-22-2335611311--------1------522-6216314----1----1--11421------------2---6-13------------------1--1-1-3-1112----5125533452222------3317445G------------111671--1-2-----1----1-421-----51-2----1--------4-----------------12--------------2---------------------------------------------------------21--2--------1-2-22----1-H--1--122131----1----2--1-311-------1---2----------1-11111111-13542431----2--21-111-1--1---8B211111FHNNNNNNNN7118713---------------------------------------------1------1-1--------1---1--1-----1--312-13-------1-6931554------13-1-111121211-------1--1---81-1-----------------------11--1--1--------111111--------2------1531-----------1------------------------------------471----------------1---111----1-1111--111--1-1111211112-2-1---------------321121-11-1------211-1----23---------------11111-1-----------------------1167-------------------------------------------------- --11116-----84626C489I78C8A556858997663865842455NZ8695236A52111-1-----22211111111---2-111---6-2-1111-13-2--3U1C4566733331233352344G4-544-44231353233213233343442231391221166D8-G-3-811121B121A1S--1---3 * b.86 Hedgehog/intein (Hint) domain
[ 460] ---------------------------1---------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----E6--------2-----------------------------------------------------------------------------------------1---12*jjghaaMFJDJRJdcGaLj*W1YRqEHJKYIOYJFLHIBQGFeQaVSSERa9BDD9JBDR7CU5---1--11--1-------1-1-1- * a.141 Frizzled cysteine-rich domain
[ 461] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------1111-----111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2211DC4-945278B67967678696888776887776577577672466656566577787755675367464645467755546A995B67747535545AA9A3C7AJKMKQJEB779AB8JE7L4x*J2NES7765G6BGB6A969E58M4FEBB8DIAAB78OC8FACAB5453T23344GDER7PB3467873 * a.221 Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
[ 462] ------1111111111--------12211111-----------1--11-2122--11----1----11 111-211111111123222-23--242222223333423311-122121112353111--1131112222111111112132------2111-1-----1412233232--------------2---111111-2-----111--4--------11111111-1-1----11-111-11111--------2-22323313113121211222232312-2222232222222222222222222222322226112222-21111--2321223121121111111111111111111211111111111111113322111121111111111-1-2111-111211211-111321-12221111111111-14111-----212231111121111111111111-23112312231-1222421223331112111121222221111111111111321-----------------------------11111-111111111111111111211111111111211-111112111142211111-11521111111113121111321212-22213-111112113--211121-1-11-----1-----1-----11122311321212111346323333221222122----11-------33111322222222422-22242222222322222225331111222121312314433233-122221--111111111211---21-1114332-2122111111--1--11112234211-111-112112131123221221-1111-1-1211211121211211111111121------2-11--11--------1-3----1-1-1-111111111111111-1--------2112 ----1-2-94A11-434223333444322222233333332331112434333323423333211212-12-11121-1123322133133242322222-22321-592844347E44343439A4B3Ce5-6773243543642443433593634431334543433934833332A3311434672A5423124- * d.240 Lesion bypass DNA polymerase (Y-family), little finger domain
[ 463] -------------------1-----------------------------------------------1 114-------------1------------------------------------------------------------------11212334314331--3444346435111111111111111111111111212----1----1-1---1--------------1---------------2121112----------------------------------1---------------------------------------------1-1-----------------------------11----1--11------------------------------1--1------1-1------2--------1-1132111----1---1--------------------------3-1--1-----------1---111111121111111111111122111211111111111--111111111111111111--1-11111111121111111111112111111112111111111111121211111111211111111121111112111242332222223222221311111411----------------1--------113211211131111222111111111121111-111-1------11111111111111111-111111111111111111111111111111111111111111121111111112111111111111111111112222112111111111111111111111111---1111111112121213111222222222111122222221211----------------11----111111111111----------1---------1-----11121111112112 -1-1116-C52411421134-352516966334253322223365823242462-42444242----3--1---2111111121-2-1-34-1623-1181231-4-A34P8JLK93B7738E6PG8Q9p*P7PHb4986H79HB16663I13D7BB6748E37431F6373283-573K113-192155313216781 * f.48 OmpH-like
[ 464] 11111111122111211111111111111111111111111111111111111111111111111111 1111111111121111111-1111111111111111111111111111111111111111121111111111111111111111111111111211111122121211211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111121111111111111111111111111-1111111111111111111111111111111111111111111111111111111111112311111111111111111111111111111111111111111111111111111111111111111111112111111211111111111111122122112111111113111111111112111111112111121111111111111121111111111111111112211211111111111111111111111111211111111111111111122221111111111111111111111111111111111111111111211112111111111211111112111121111112111111111111111111121111111111111111111111111111111111111111111111211111111111-11111111111111111111111116111111111111111111111111111111111111111111111111111111111111121111111111111111111111121111111111111111111111111111211111111111111111111111111111112111111111121111111-111111111111111111211211111111111 24213362832221322242323323334331425422422222224332423242223224222232-22122333434233323234262233322221324551272C564753445163287372Hd5155A1534646982441142272434534427322454D42333543Y3344487F94742234223 * c.22 Ribosomal protein L4
[ 465] 11111211111111111111111222222222111111111112222221333111111111112-11 2221222222222222233-33223233333333332222222223222222222222222222222233211111111111111111112111111--1211111111111111111111111111111111111111111111222111111111111111111222111111111111111111111111111111111111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122232222232323122212221221111121112211212111111112111221-----112221111122211111111111-222222211111111111111111111121111111141111111112211111111------111111111111111111111111111111111115111111111111111111111111111211111112111111112111211111111112111111111111111111111111111111131211-1111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-111211121111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111321211111111111111111111111111111------------------1------11121111111111 12-1422-31132222223235232423322223332323323222223222324322233343333313433443333335544422212124261122132222125144432443434243A83B2If5-8682323734633334373382353444223521333212222223G32332364A3AD2232222 * c.101 Undecaprenyl diphosphate synthase
[ 466] ------2--------1-----------------------111--------111----1---------- --------11-----------------------111-1--------------------------------------------------11-1-1-----------------------------1--------------1-----------------------------12--------1------------1-11111211131122-1111--1211---1-1---11-----------------------1--------------1------1----------------------------------------11-----1--------1---11--------3--1--11---------1--1111-211----------1-------------------------------------111-------------------------------------------21---------------------------------------------------------------------1---------1--------34-3351---------1----------------------------1-----1---2-----------------1-------------------1------------------------------------------------------------------1-1-1--1111----1-----------11111111111---------1112--------1---1---------1-----------------------------------1-11-------1--------------------1--22-------------------------------------1-------1----1- 3332461-B46211522434343343522343334322324224223421435542323443145453122423334224443543444342225332233724662447B9DFGFDB988CJ9SSBZE**Z5fLk8EAAQ9HuFCCC98J99O4C99C7AA9638484B68643-441F111127ABJ4HB2143231 * d.305 NAP-like
[ 467] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------1-----------------------------------1------------------------------------------gZjghlNPKLHQXOvdGiO**h3fZqMNLJdMUUQLSNFDXGKcNaTWU5AAFbQ92JBED12D2------------------------ * a.271 SOCS box-like
[ 468] --1----------------------------------------------1----1------------- --1-----------1------------------------------------------------------1-----------------------1------1-----------------------------------------------------------------111---------------------------------------1--------------1----------------------------------------------------11------------------------------------------------------------1-----------------------------------1--------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1---1-----------------------2----------------------------------1---------------------------------------1-------1--------------------------------1-----------------------------------------------------1----------------------1----------------------------------------------------------------------------------1--------------------------------------- 3235678-MA8-677556465585766562454655557574455455454556456544346446551453544444445344444546B4565A454558576836GACEGIFDICDDCFDCHIHHAd*E5FFICCDCDEDCA6BFBAFECJBDCCQ8JQ996E9E69AEDB64546v4545598BB566497B687 * e.40 Cullin homology domain
[ 469] --1----1------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------------------------------L7653345567999H97555489A3D98CBC89CE79-----------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------1--1----------------------------------------------------------------------------------------1-1------*---------------------1-----------------------------------1--------5gla*LRNWh*S*g-dLji----* * f.43 Chlorophyll a-b binding protein
[ 470] -----1-----------------1322-1-12--1--------13-21-1--------1--------- --2--1-12221-------------------------111----3211111-112-1---11221-1222-----221--3-1111113322-211---11141--1-1---------------111-1-1-21111111---3-111111-22221---1-32-11--1------------43222113124337464664666666444444666131433322222244144444444444444233434233223-3322111231--3112222331111122-----------11111111111112443324442-5132-------3-421--155422---1----11--21--2-222-3-23-1---------1-3331-121232------------2331312-22--233222222212-1---3232122333--------1----111-------------------------------1--------111111-222211--22222111-211211222312222-1-1-2116---3------------11-11---2-112---1---1----112-184111--1-------1-11111111--13--441-12-11113333333533333335354-----12------22221222224255522-222255424225322222332333324444444443433434242333213--311112212211---------1111112-3333232-22211--2111-111---1-----11--121211---1--------134454444455343--------------1114-----1--------211------11-1---1111---1-1112222211111-111 --11--3----4574344446532325333322555233333333321544333334233331111121111211111111111-131436245432222134223-283D523412111113-753315D1-312121231231233224222111111226434D9BAC--13-32111125-222251-8453354 * d.114 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
[ 471] ------2223333242----1---2---1--------------1------------------------ 315--13233321211122-21--1122222-111122221---212--11-233-12--1111313-1-133335342211221111--11-1------1-12--4-11-------------------------22221----112211112211111111111244311111111111112221112-2115555565546667854233315571--21112111114413333333333333333334334312323334533125343631112222-11111111111111111111111111111122111222221---222222212111---111111111--112212121211---11111-B5441111-1112231111111122222222223-11111121141-54434435446411321242323323311111111-2221121-------------------------1----13111-1---1111111------3-1111-1111--------2--1------2----------1111111------1---111211111111111111111111121------1111-1----------------221122--2-1-111122211112132121----1--------31331123332333333-324343333433333333322232221332323233343233443323333--1--------------------11-1--111--------------1------11----11111111-1111-231----------1--3-----1----2244444333------1---11------------2----2-1-1--------1-------12-111211225-- ----212-7421--24446522294762232232222222222222533646875545223421311411123-21111211112221322442221221312-3--3T89755444-1--1-11-1515E31212-1----111--1-1-114131-521146334437223351552P24223589A4741344112 * c.70 Nucleoside hydrolase
[ 472] 11111111111111111121111111111211111111111111121111112111111111111211 2321311111111111111-1111111111111111111111121111111112111111112111112211-112112121111111111111111-1111121111112222221111111211111111111111121111122212222222121121212222221111111111221111111211211111111111111122111111111112112222222111111111111111111111222211222222211222212122222222222222222222222222222222222222222222222211111111111111112111111212112112222111122121111121111211122111212321121113111111111112122222221131211122112222212222212212212211111111222212121112111111112112222222222111121121-11111322223222222212222222221222211222222111112132211221222222222111211112122222222222222222222111112221222222222211121111112121221112111111222222223222222222221-2212211111121121222221222222-22222222222222222223222211122222222222222222222222221222222222222111111111111112211111111111111221222232211211111122222222222222111111112222111111222212222122222111112211111112221211111111111-111111111111111111112121111121111 1111221-41111111111-111111111-1211111111-111211111111111121211111211-2111211111111111111112112112121111322123153332532221223234224E313233222232221332122123322122243222322222123322I222-233441422223322 * a.203 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
[ 473] ----1---1---111---------------------------------1-1----------------- -12-4--------------------------------1221--132-1----111--1--311-2113111-------------------------2---2123111-2-----------------1-1----------1---1--11-----111---------1--12------------212-----1--3333321212232231-11--322--2-1121-----11-------------------1-1-------1----------------------------------------------------------------------------2---------1------11--1------------3--1111-----1-211-------1--------------1-1----1-1---1------------1-22-----11--------------1------------1-1---1111-11----1-2111-111112112321111111111222112211231--113-11-1311-21----1-----------------2--1---------------1--1-11-132--------------1-----------------1----11-212121--111121111-1---1-----------------11-----1--1---1---1-1-1---------12-2-----------------1--11--1-----------------11-11111-1--1-----------------------1---1-2211-2-2-------11----------1-------------1121111111--11---411------------------------------------------------------ ----24C-633n44444G4C67586AC2456345539455432544765CA8FDAC788AAA1112-3111-22111121111111-11555497C2112235525-9g2HB5B8DE7BB9C46FFDB8Ce71C7A9BBCA69D8ABBE76B9DDCC6A7GB8EBC5D78B46B52PC1N223B2833B72241368JH * a.266 Indolic compounds 2,3-dioxygenase-like
[ 474] 113-1-2322223323--2111112---1--------------------------------1------ 13914---------1--11-12--5711111333331369221311---11-2121----1-B-3495551-------1---3---1-------------1-245-5----------------------------22211----5-11111---------------1-2--------------22-------1-----1---------12---1----21-----------1--------------------1---------------------------------11-----------------------------------53-24444344434-4------31-21-112-311332-213-------4--4232-----24FGH41337495111111111-1-A9E88CAD562-62251284328C7523-66144445564444444463331521------------------------------2351-45445ABBBBA22221BBCC22221285GCAD5-2665433118251A2132-1111-----------2221-3-4111121111--1113111311-133-4-------------------------222--4112-4-112222232111111--1-1----1---------1--2--3332322132-3333212323322332331------------------------51--1112----------------------------1321---------------1111111-214166663284464553433---------1---3----------1122222----------2--------------11---------------------------2222-----13-- ----211-----11-21222121121222232211111111112222211112222111111-----------1-------------1---11-------1-1----263F23223822222426E252362-32422224326232222B1292623426N2874B6AD8B356-13-8---2344672761122212 * a.56 CO dehydrogenase ISP C-domain like
[ 475] --------------------------------------------------1----------------- 3331------------------------------------1---1---1--1-1--------1-111----------1-----33333-------------------3------------------------------------3-------------------1------------------------1232222222222222222322212222333222222222243---------------1--------------------------------------------------------------------------33433333433443433333---333--23332333333332333332--53333333----337593345844822222222223-6676736733333333433444334-3333336666333--------1333-466--------------------------------333332433444733333333543336364343333--533333333--364333333363-------333-33344-4344458446533323333333-3--3-4546-4445565555555555554---36-344333333633383633363366663---333332-33363333333333333333-3633633233336333333---3333333333333333333333321223233356666666664---------3333--835-------------------------3333333333633433544---------3344633333663333333333336------333333443333333333--------------------------4-43344244-3-- 1-----------11----1-1-211-1---------2212222------1---1-----311----1---11---11111-------11--1-12-1------------11--21---------21-1-281-111----1----------1-5----1-2---1---------1----------1--3-----311-- * b.152 Flagellar hook protein flgE
[ 476] 11----1111121211-11111----1---2-1-1--------------------------1112--- 122-122144321212222-211124222222-----35621232121-22-544222--3341123211-111111111115-----3333-222---111111-1-1-111111-------1--------------------11-------------------1----------------11111--11133333322223233222233332331113211122221111111111111111112111121--11---1111111121--1-11111111111--1111111111111111111111111112111111-22122222222121-222122221-11-11--11112-2222112--1-1-23111-1111-1222--112111-111-111114-11411614561-4225321531233223121311591151111111131111-11-----------------------------1-12114HHA844443433333338A55451594H34652212411322313339122--1-411111-11112---12--2212213111-----1-1------11-1--2--122212111111111--1----431111123222111112211112122233--12111------52434214444443444-4434454444444343443242473235544555555555545333333331-211111111111---2222222222-1232111-111111----111111--2212-44444555144462311111112111-222422232322232211111111-------1--------------1---------------------------1-211-1---1-11 ----111-1--21312331322256671123222121221312211443365363413122211-11-1123--1111112----1---49332341-11272222--2-2234342221-112111-125112121111321212111111-325434121-32------1-2---118111-1---333--1----- * e.44 2-methylcitrate dehydratase PrpD
[ 477] --------------------------------------------------------1----------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------------------------------- 6434995-C33577754434444454344444445444243444444345445433544555535444155455555-4545555545548445554444454999266F8LGIPIQDEECDDDXLEUCi*J3UFZDEDCICEPFCFFB9NDBeEMEDD58a75586J55M6E642232F11113933H4C8227CBC4 * d.62 Pepsin inhibitor-3
[ 478] 11--11-----------------1-------------------------1---62222211------- 2231222222222222222-22113222222323332222222222222221222222--22222222222-1111112222111111111212111--111111112111111111112222122222222222111111111122222222222222222222122222222222222222222232122233333333233333322222233322222222222222222222222222222222222222222222222222222222212322222222222222222222222222222222222232222222222222222222222222222222222222221222322222222232122221222222222222222222222222222222222-11211222222222222222222223222221222222222222222222222331111111111111111111111111111112222211111222222222222222212222222232222222222222222211123232222222222222222122222222222222222222222222222221111122222111111111111111222222222222222222222222222222221-2222211111122222222222222122-22222222222222222222222222222222222222222232222222221222222222222112222222233222222222212222212222222222222222222222222222222222222122122222222222222222222222222222221211111111111111111111122-1121111111-2111111112122212221221 -1--1---1---12---11-11-1-1--------------------------2-111-----1-1----------1-----------------1-1-----4--1-1-2-------1-11----------1----------1---1-1--1-------------1-1-------11-1-----1-2222122-311--- * a.79 NusB-like
[ 479] 11---1-1111111112-12112111111311--111------1--3-----------1-----3--- 1121232222222222222-2222232222222222222221212222211123222211212212122121222222113111112122-2-----------1---1-244344433422221-----1-----1111111122121122211111111112211---11111111111111331111-22222111222222122223221312123232222222222222222222222222222322212122131212222222221112223444344333333333333334443444444444333332333311122221222232313112333211322111-1111111-1-1221-22--2111122222-11112221211122222222222-11111111211122222211222111111112111112111111111111113111111111111-------------------1111121111122222222222222222222222211112221121222112222111133111111111111111111111-----1----1111211111122111-1111211111111111111111111112222322222222222222222222222221-1121311-11133232333333333333-3333333333333333333333333333333333333233333333333332133343334433311212222211111223222222222221122211111122224222222222222222222---------2222222222223222222222222222221-1---------1--1-32111111---11-11111-11111---11112-2111211- ----1-----1-1-----1----111--------2-------------1--2-112-------1----1--122-------1-1---------11-------------42311---4231121423321AW41733332252121121-3231132423-------1----1-------1--3--11-----11--1-1 * a.98 R1 subunit of ribonucleotide reductase, N-terminal domain
[ 480] 33333333333333333444444343333334333333333331121133333344443331113233 1111111111111111111-111111111111111111111111111121111111111111111111111111111111111111111211211111111111111121111111111111111111111111111111112111221111111122221111112221111111111111121111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122111111111111111111111111111111111111112111111112111111111111111111111111111111111111111111111112111111111111111111111111121221111111111112211111111122221111111111211111111111111111111111111111111111222111111111111211111111111111112211111111111122111111111211111111311212211111111111111111111111112111111111111111121121111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111222111111221211111111111111111111112111111111111111111-111112222221111111111111111111112 11111111513123244342322222222222222222222222223234334344433333323222-3222223332332223233326242232222233457115154643141-32222782417W31434121171251-121131132322224224231414244222221Q1111195A72731111113 * d.77 RL5-like
[ 481] ---1--1111111111-1111111111111111111111111121111121111-1-111-113-111 112-211111-11112222-22111222222122221244-31111211231122123111122112222-1222122111121111122221211-1111212112111111111---1111-11111112111-----111--2-22-11---------1--1----1------------111--1--111111112222211321111122222111211111111112111111111111111111111--1--1---112----1--11111111111111221111111111111111111111111112221111-1-21-------1-1111111111---1112-111111----------112-13222-1111111111121111111111111111-11311311112-1111112121223122331322221332222222211111112-----------------------------1222112111323333232222222433332332211111122211222122121211111222222222211211212241122213112-223222225--1-2221111112212211111111112112222222211213212323222232222222223--1111121111123333333333333333-3333333333333333332223333423433333333333333432433332-22233333333321131121111-12121122222213333222233333311121133333433222321332222222222122222222222233112222222222222111111111----------1------------------------------1-1111111 2--1--1-4-3-1-2222142232233113212333121332111212222-2-1-211223121221-1211111112121112111142-22431122232134-141541312-1--12-21--5-5B4-13412-131-3---1-1-122--1-y1-6--1-21-111-4-1221E11111B5741331222132 * a.130 Chorismate mutase II
[ 482] --------1111111----------12------------------------------1---------- -11-----------------------------------------------------------1-1------1-------------111---------------------------------------------------1-----111-221--11------1---11-----------------------1----------------11------1-------111111----------------------1-111121-1-111111--1111-----------11---------------------------111--------------------------------------------------------1---------11111---21111--------------1--1---1--------1---11-11---------1-------------1-111-----------------------------------------11-1-------------------111--1---1------------21-1-1-11-----112-111-1---------------------------------------11111111111--11--112--1----2----------------------1---------1----1----------------------------------11----1--------------1----------------------------------1-1-------1--------1-----------1--------1---1-------------111111111112-11--11111------------------------------------------------------------------- 111--1--311-111-221----1113111---2321111111---1111333433211221-----1-1----------------------2--A-----1-----141OJXUYXSFGFEEHHSPGPEj*O-TQXEHGGQHGLIEFDGDMGCQGHKINAADOFIQDGDFj6A8823414---435A9819L65EEBE2 * b.74 Carbonic anhydrase
[ 483] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1--1------1---1121111-------1---------------------------------------------------------------------1------*6I356111111-2321419L3-4342221312421-21--12915133ZgI9********VRS--11-----1---1----1M----- * g.31 Invertebrate chitin-binding proteins
[ 484] 11----1-1---23-2-------422231411-1--4-12-1122-66--655---262--------- 556112---1-1-----33-31----32333--2-1--14-342---24--1111211--111----12---1112--1-61--1---31--22-----7312--191---------------4--6758-2E1111115-1--18J8387W--111-----331A6762-------------1--1-------------------------------2---2----------222122222122122---1212-12--23111--13-2-------11-111112133332322243111111221111--23---444-12---------------11-------11113-27C7-172--21221-3B-124671-78-9431143122G43411111111112-46245272-34-46662544863654-13312-11----22222222445--188------------2344-1942-22-6-32--131-1----3332221------1111----4211233--35211-31321216--72--1-2-1-----H336111346--51-622221263441D2A1111--421412--1-13-1-22422145-12446-23432-522--31121--1-11-3--11---3832A------45121733422333732-1233223323441113224312648H111213321411231127-123113--51112111-21---713313321-21-125-1-1---2232625---2-21112-761111122313121-671-----1----5-348696722132--234224445434--632111----------7-1--------------------------2---------1-- ---------------------------2211---------1-------11--------1------------------------------321-111------1-----2----1--11------------------------11------1------------1-1----------1---------------------- * d.298 RelE-like
[ 485] ------------------------------1-----------------1-1151-------------- 3318337677777955555-565565555555666669798B8F6882778898864A7777849A9AA98666634444754-----221322224--2312344334---------------7346644335422245---33-------------------------------------333332236667777787767778876666667775666545555555685555552555555555555575546543535345555523445444444554544433333333333555555555555557744477755555855555555554333688945435733545545555454555523421-3-----------------------------------------------------------------------------------------------------------------------------------------------------------------2----1---------------------------13-31-1111111111111411111111111---------------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------33333333332342322--------------------------2132233323---3 -------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------1--------------- * d.11 Penicillin-binding protein 2x (pbp-2x), c-terminal domain
[ 486] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-----1111111122112211112--11111111111--1-112231112211111-----------------------1121-111222-2211132315--GOQKPGbGGNGJRI*jGfH**c2iN*GJEEkAIyXHJFIGWEFmGMGII57GK9674C67I446D----B-13----1-1---1--11- * g.20 Blood coagulation inhibitor (disintegrin)
[ 487] 22-1-266666666661332244A122111215422324444423222365642---3--33234--- 2256622----11111111-121112111111222212332211--12-----1-11---11112352221---------1322322311111111---12111322-3---------------4433312233244487---152242222121111111122222222-1-----1----33333---4344444433434343346544433343452312------321-------------------1---22-------1122-1----111--------------------------------------------121223333333232--11133422-1-4--64EE8B7311G91112-2-242---1-----22121111111111111111-111-33133132211-11121121111113---11211112111111111132213122-----------------------------1--1-122222544745544435567444434666454422334342222243332235122222222222222444-BE788855967771DAD4C6C354434127D21-214444332222222222341155211-2-2--1211111-111111111111----2328------2-3221-3222323233-233333333323333233111121--3111111111111111111212222--111111111111-------------3-2212222122111-2222-------11-2-22222331222232122----------12231111111-22--------------1131111111--------2---------------------------1-1-11111122-1 -------------1----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------- * d.349 CPE0013-like
[ 488] ------1------------------------------------------1------------------ 21425-------11-1111-12--12111111222222231131---------2112---211-11332-2-------345531-1--1----------1413331311---------------222224222131111-11-2121132212212------111322411-----------43211221313666665552644554544453464431637245545447322222222222221422341152--23---44--21211221122--3----1--11111111111-------------121111211-11146454556515133112222235111133144322112322213-1-3135223-1111531-12211211222222222224-2331332234514773555666442412143635344251111111123323645--11122211112122-2211-22-----113532222244345442555433335455445433365122232233233332234232222111111112233222111-225353445-4742444422232322142211111111---------2112-22333222121222222222232222222222--13343------22232342222222222-2222222222222222222343223322222222223222222422222221-222222222222---22221222223132211111111111211133333221221233332211112121211211111111322221111122322111222211111111132--1111--------2--------------------1-------1211212221211 ----1--------------1-----------------------11--------------------1----------1-11-------------------------1---------------------------------------------------------1------2--------1--------------1--1- * a.49 C-terminal domain of B transposition protein
[ 489] 33333334233333332333322131122321232211-11111112221331121222221332332 21111222222221-1111-1-22111111111---22211222-3323-1211211132322212122122222433-2322322221121-1121132221221122-111112-------11121111111-211221-11221111121---11111111-1111121212-2112-123133221-1122222222122222211111122212121111111112-1111111111111111111112121121121221122111221111111----1--11111111111--111--------1--111----1--1122222221211-111-1--211-1-2121211-1111111111112132221111--1-1111121121111111111111---3--111111--11212-211--11-112-2-1-11121111111111-122212222222222232122222223222222212-21-1---1------11111----1111-------1---------11------21-1---11111111111-1--121111111121111113113111121231211111111111112-11-1--2112-111111111111-1-------111--1-1-11111--111121111---1--1---1---1---111---1-1--1--1--11-1---111111111111111111-11-1111111111111111112111-----------11111-1---1-------111211-111-1-----------------1111111111---1----------1-1-1-111111-11121221121----11---1121221-111112111111211122111111111212-12 4222232-62122113222123114222232332531232322222332343422324265622232212333423413422123234325222231122233222-153726433A4443424253347M223555255427734324325354553646E14324324931242213N2212336A52232392531 * b.51 ValRS/IleRS/LeuRS editing domain
[ 490] 224242555555555552322212---1---1322222222222222222322266776652222--2 24724-1-------22222-24--22223232222223322222----------------632--1-2322------------22-22-161-2--------22--4----------------1----------------2221-46666644444322222744977632222222222222-12-662---------1---------2----------2-2-1----1--------11--11----------1--1----------------------1-------------1------------------21---2-1---242-2-----2-2-2---2222---2---22222222-622--3-4--921244222222--2222322222222222222222-1-------232-222322322232--222222222222222222222222221222222222222---------------22222-2222222222223426444433424444224252222222222532232222222222224222222222222224--1-----------2222223--333352---------------------------224422--225222222222222222222222--2-22422-22222223222222222222-2222222222222222222222442222222222222222222222222221-233323323233221222222222242-2-22222222121322211111-1--44-44445555464654444----------232422222444445555555222222222-2222222--------6122222--------------1------24222242222--- ------1-411----1121-----1-1-----11-1----------121122-321--111--------1------1-----------1-3-1--1-1----1-3--1--31111-1-1----223-1-121---5-1--21-3---1111113----2-1-13-225-1-3231--1-1-1-112111--3-13-1-- * d.283 Putative modulator of DNA gyrase, PmbA/TldD
[ 491] ------------------------2---2-24------1----------------------------- -----11-11111-31411-12--1311111141113332-1-12---122-1--1-1--24--3-2222--------2--2111-1----1------------2-11---------------------------32111---3-DD53445332233432322237534335333343433331------21333333332323332233311332---1322------22233333333333333333311-------------------------------------------------------------------------211111111111-11111111----11--111--11--------112-21111-22-2343552225324344444444444-5454444423--55556638775554---21522441322222222211133212-------------------------------11--35422433544333335573333333533354211223121115211322141211211111111---12------11111111--------1------11-2---------1-1-1111111-------111--11-1---1111-1-1111-1--1------1--------21111111112122211-11-111111112111111111411--1111111111111111111111111----------------------------1112-------------------------31223235452334314441111111113------------2-11111111111111-13111---------------------------------------------------1-- 11-1224-311-11221211222222211222221221-1111111--221222222111-1222132111121111-111-111131112111112221121231-2c62-222232-1121245151Wk8-A322121222322221-321413222---1-31----3---22BA6*754955324222476755B * d.237 Hypothetical protein YjiA, C-terminal domain
[ 492] -------1------------------1211111-1--------1------1----------1------ ---1----------41111-1-1121111111-112311-11111---------------112-211112-111111---1-----------------------1--1---------------------------------------------------1-----1---------------1--------1------------------1--------11--------------------------------------------------------------------------------------------------------------------------------------2-----1--11--1-------1------------------111-------------------------11-1--111-1---1-11-111111---------1-------------------------------------1--------------------------------------------------1----1---------------1--12-12-----1-----2111--11-----13-2------------------------------12------------2--------1--------1-------------------------------------------------------------------------------------------------------122-----------------1111112222---------------1----------------------111--2111211111---------------------------------------------------------------- 111-111-421-11122212222232322111122232222222221222222211222222112111111121111111111111111121211-1111111121-242FZaQSYIBGDFFHFsdCT8**J-eJmBCBBJBGIEBEBFCI8BXCGCEI58DE9A52T9AD57A6121281--2222422113121111 * a.194 L27 domain
[ 493] -----------------------1111111111--111111111111111111-11111111111-11 112-111-11111-11111-111111111111111111111-111---111--111-1--111-1111111----11111-1-11111----------------11-----------------111111111-1111111---21111111111111111111111111211111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-22-1-111111111-11-11-----------11111-11111------------------------111--1111111---------------11111111-------------------------------------------1---111111111111--1111111111111111111-11------1--1111111--1111111111-1111-1-----------112121111111111---------------------------11---1-2---------------------------1111--------------------------------------------------------------------------------------------1111111111111-----------------111111----1311111111111111111------------------------12111112222222-------------------------1-11111121111111111111111111111-1-- 43445231C4445334345544445445544444544444444555453455264444343345444514544534514455564544445434674454444455567567978876565476884D3Gh9297D7465656765656685594F5665CU354445648H7614454V4445546474814357573 * d.215 Smc hinge domain
[ 494] -------------------------------------------------------------------- --1-22221121-121122-22--1322222122324112132111--1-------22----21313B891----11211-22-----11A5-8112---22113---1----------------1-------1-76666---823--3--1--22212122--11111--1-----2----1--------127685866756669771-3315569-1-31--41112121321111122133221111242121-31--1---44--1112-1-----------1111111222122----------------------1-21--31321-22131-321321-13--3-221531-21-21-1--1-112--211121111112221131111211111111111-21111111111-111111111111211111121311211--------1---1121----------1122--22121-22-1-1111121-22222222222344442212444425322112111112113116221411111211321111111121222-32-------1---------1-------2--1--------------------1---111221311112111111131111111211122--12113------22224233223333333-2333233323233333332222221122322222222222222232322223-233333333333--211111122123132-11111131211112111111111222133432233232222432111111111121111111111111222222222211111-12223333----------6---------------------------1-----1--131 ----1-1-1--------------2-21112111----------111--1----1--1-2---------------------------1---------------1--1-11-P6522426761265792869L6-76A664525463-245674443--23----991DPGBG11-1---1-----1-----1--11---- * d.118 N-acetylmuramoyl-L-alanine amidase-like
[ 495] ---------------------------------------------1---------------------- --------------------------------------------------------------------------------1--1----------------------1---------------------1-----------------1---------1---------------------------------------------------------------1----1111----------------------------------------1-----1--------------------------------------------------1------------------1-----11------------------1--------------1-----1---------------------------1----------------1-1---------------------11----------------------------------------1-------------11--------------------------------------------------------------------------------------------------------------1----------1----7-----------------------------------1--------------------------------24------------------------------------------------------1--------------11----------1-----------------------------------------------------------------11-----------------------------------------------1-- --------222-------1-2--1--1---------1111111-1-----1-2---------------1-1-------1----------17---2------------34-iecUfVVNPKHOMNggIVLl*V-aMqKLNLTMKUKBPRJGRHFaMQFGW7GJ848434587568-1---1--11--1---211--1--- * b.66 4-bladed beta-propeller
[ 496] 22----1134433331--22211231131112------------------------1----------- 1111212222211213333-32111233333122222112211112212111112111--32232121411111111113HJ2-2111------------------------------------111--11112-11111------------11-----------1----1-----------111211111122222221222222222122122223231111111111112332233232333322222111111112111111211111---11111111111111111111111111111111111111111111111133111111111111131111111111131111LI111112231111111-2-1--1--1---11--211-4---11121211112-122112121-------------1-1--1121221223221111111121111212------------------------------1111112226222212422222212333323121434412343232333334213312111221111111111624-132332211311411214212211111111114321112211-1-------23121223212212111133443159366255463B5--11621------54445526667676766-6666666666676666665665333238777778877888778555544351-244444444444--12---------1223-44443323332233411111112131222221111111113111----------3444333334433321111111111111-11-------------------------------------------1111111-11---1 -----1------21---1---1-------1---------------1-----1----------1-----------------1---1----1---124--------------1-111-2-1---111--1-11------------------------11------------1--32-------1--1----2--------1 * a.184 TorD-like
[ 497] --11-11111111121--2--11111111111222111111112222312222111-11-------11 1113433222223232322-22112633233123332433111122322221645123--22324563441----1111131211111111-12-1--------2-1----------1--------1-------1222332222111211111122111111111121211111111111112111122-22333333344343333333222334332222224444452322222222222222242223221123111112211221221113132222112111111112111111211211121121222111222233223333333334222333332231331324233321221234333131-11----11111--21-11---11-2222-222-25-22122122131-311-23355233211111-1----21-1111111121111-12---11111--------1-------------1---1111112222222322222323334222221111-11112----1-2--111--322-111111111221-1-2111--31233331221221212111112212--12111111-1-------1111111111-1--11-1-------11---111-1-----1-11------32--11-1111121211--111211111-111111112221---3----------------1111111--1222222222222---11111111112-12-1112-1--------111111111-12-1222111111-1-12221--------1111211111121-----------------111111111--------1-211111-1121121---12211111121122222221-1- --1111--21--11133221111212222111111113121222112137335543232233314112-1121132212212221112212231213232211112-1-152321221221211121124G2-315211-2-2113212111-62312211-135216-2359--114181112264762442222111 * a.208 DhaL-like
[ 498] 11----1111111111-11-111-12221221--1--------2--111-111--------111--12 111--11211111121111-1-1112111111-1111211-111112-111111111111---11121211-----------111-111111-1111--122113121211111111111111111111111121111111112121222221111----1111222231------------11111---222333333333333333322222333222111111111131122222222222222111111---11-----------1-----11111111111111111111111111111111111111111111111-1-12222222222211222111111--2---122-211-1-1--1---1211122111111213111121212212111111122-112114111111133111111111211211111111111111111111111112111111111111111111111111111111-11321122221111111111111111111111521112-111111211212131111211121-1111111111112---1-31-1-111-111-111--111112121111111111111111111112---11221111121111111111121111111111111111111-11121111212222222222-222222222222222222222211212222222222222222222222222112222222222221111111111111211211111111111111111111113111122222222212222122211111111111112222222222233232333332222---111----11111111--11112-----------------------1-------2211 2211221-D56-9B2343233333323333333222222222233322333333443433335442323333434332333444333334544333111131321211242131112111-13111111483-3131-1111211111--2111111121112311111331233367171115733863732342212 * d.44 Fe,Mn superoxide dismutase (SOD), C-terminal domain
[ 499] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111122-2111112222211111211111111111111111111111111111111211111111111111111111111111111111111111211111111111111111112211111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111121111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111-1111111111111111111111111111-11111111111111111121111111111112111111111121111111111111111111111111111111111111111111111111111111111111111111111121112111111211111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 21112221A4313231222122222222232223221222222333222233232222122222222212222223313322222234422222222222222357126232422233331232642847f7-56C2332524343333152122232323123222332223223333e3333398B72752332232 * c.21 Ribosomal protein L13
[ 500] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111211111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111121-111111111111111111111111111111111 32112211933122322232222222222222222222222222222222222222222211222222121322233323222222333243222222222224551232323222222A52328C2J38dC-3492223C12K23222121233532223223222626233323333a3323365783432222221 * d.55 Ribosomal protein L22
[ 501] ----------1------------1---1-----------------11--1-13-----------1--- 1-2-3112111111445----2--25-----232122284121121221221232321--1-113327431---------1------1111--1------211-222-1--------------1-------------------2-11--------1---1---1---131------------113-----1-3444443241334444224223433---452211111124311111111111111221111-1--------11----1----1------------------------------------------------1------1-21-1-1-------2--1------22--1--------------21--------242213-11121-11111111113-76566365-1--2112--311122-111---131331-11111111123313-22-------------------------------14-1111133443424111122543333113242-21-1--21222223315-13112131111111112131113---121-11-1121--------1-11-3111---1-1111112222222221---1--11-2-22132-22332-1222221121223---2---------11-1-112111211111-1121111111111112111122--1111-111111111111112---11111-111111111111---1-1111-----1-2-1111---11111--144544211241-445435752333443442---------112112122221113243333333-------1--1222-----------------------------------------------114 ---14211----234457545356A644333333543222222333887889874723244432222221122113212251114112158354315341171525-352E1422452222431632313G3-664122232333321212212253673645632541194322118-11--14A5B6559216343- * e.5 Heme-dependent catalase-like
[ 502] 11111111111111111111111132233313111111111111111111111111111111111112 2212212222211211111-11111111111111111111122222212112222222112221111222111112221111111111111111111--1111111111111111111111111111111111111111111121211211111111--1-1112-11211111-1--11111111111112222222222122212211222222221121112222211-11111111111111121111-----------22-------------11-111-11------11--1-1-11-1---1-11-111111111---111111111111-1112---1111--1111322---111-111111-1121111111111-1111111-11-11111111111------1--211111111111111111111--11111-1-1111111122211111222111111111-111-1-11111-11111111111---211121111111111111111111111111-111221111111121-21222111111111112212111112222322222111111111111111111--2-1111---11111111-1--122111--11121111111111111111211111-121211--11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111---111111222221121111111111111111--------1-212222222232222222211111-111111111111111111111111111111112221-1111111-111111111-111--1-11-11111111-1111-1111111112111 22222221722222212422222222322222222222222222222222223222212222232222222222222-2222222222232222222222242234223254443433354263593544R4-5582333333323342233333433335522252822434233343N32243A69A2874543232 * d.241 Ribosome binding domain-like
[ 503] 11111111111111111111111111111111111111111112212111111111111111111111 2111111111111111111-1111111111111111111111111112222111111111111111112112222222112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111121111111211111111111111111222211111122122222221122222222222222221121111211212121111111111212222222222222222222222222222222222222222222222211111111111111111111111111112111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111212122122222111111111111111111111111111111111111111111111111111211111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121-11111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111211 2211122183322222234222222212222122232212222232222232322222222232333312322332324232332333326222211222234335116131111121-11-237A-B16b7-24A121151165111-121121213112111113522212112122H11112746F3741111111 * d.140 Ribosomal protein S8
[ 504] ------------------------71122313--1-------126-28-7LCA--------------- 123-1---------223----3--21-----112224122-2-12--------43-------1-3-24541---------4-1--2--337--9--3---3-1-531A5---------------1--1412377123321--121553F11-2233---1--38-5AAE-------------22----1--1------1--1--111-1-----112-1---71-----11---------------------1-----1--1---------------1--------------------------------------------12212-------1-1-412-----12---212233-11--31-111------8966311111126675124234833333333332-FIMGF3IU261125526828D95222242-31232212---------32212569------------------------------113--111-1211-32411114334211---2-2-322--33465344-3341-31B423483-------11429B27911263395453-B2A445359--3-64431--2----------------12-----221362715294677736167775513753----225-------2---11-1-------------------------------1---1----------------1------------------------------222-2-222-------------------------1444433477A25345332---------3---1-----11-115512112222------B-33--11----------1--------------------------11---1-1--9-1 ----12--------412111-1-322-221122122211111111111---1---211111-------------------------1111--2---1-11--11------2243542-112111-3121562-1122-1-1-11111--11--213212123212127231--11----------1--12----221-1 * d.243 Colicin D/E5 nuclease domain
[ 505] 111111----------1------11221111111111111111--1--11111111111111111111 221121111111111-111-11111111111111112111121111111111111111221111111223111111111111311111111111111-1111111111111111111111111111111111111111111111111111131111111111111121111111111111111111122121111111212122122211111122111111121111111-11111111111111111111112111111111111111111111111111111111111111111111111111211111111111111121111111111111111111111112112111111111221122222111111222233333332222232222233333333333-3333443333311221111111113333333433333333333333333333333333333333333333333333333343532333331111111111211111111111111112111111111112111111111111111121111111121111121111121111111111111111111111121222222222222222222222222222111121111111111111111111-111121-1322111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111122222111121111111111111111111111111111211111111112111111111111111111111111111111111111111111111111121111112222222222111111-111-11111111111111122222222221111 11--111-1-1---1-21111111-11111111211111111111121-2-2-1--112---211111111122111-1222224121221122121112-111-1-2215462214221114-76-816G313261111322121221132-22334312122221122113111111I11123221315131-1113 * a.97 An anticodon-binding domain of class I aminoacyl-tRNA synthetases
[ 506] ---------------------------------------------2----111--------------- 1211322222222211111-111111111111111132211331223132223332231144212233432233333311331123221111-111111111115111111111111111111211111111111111111112122222222211111121111322221211111211111111111112222222222222222211222222222231221111113122222222222222222222122211222222222112221111112222222211222222222222222222222222222222222211323444443334222442332111112241111221111111111111111111111111212111111111122222221222-2222222211212222222222222212123333332332222222222222122223222221111333313333133111111111112222223223222222222222222222222221222222222222222332222212111111122222211111111111111122222222211113311111111111111111111112112222211111212122333332233332322322111112111111111111111111111121-111111111111111111111211212111111111111111111111111111111111111111111222212333211111111111111111112222212111112222322222222122222212222211112232321212211222222221111112111111111-11111111----1-111-111---11111111211111111111121 11--11--412-111---------------------------------1---------------------------------------1------21----1-----1513221121----11111-1-171--11------1211------11--112--1---212118--242422C222114313-371321113 * d.167 Peptide deformylase
[ 507] -----------------------1122----11111--1111122-1-1-----11----2---1-11 132-3---111---21---------2------11213-6611--3----11-121-----11--2-2341-1111111-------11111----------2---22-1-----------------1---------11132----212111111111111-1111--222111111111-111--1-1---113333333343542124213314254122212211111233-111111-1111111122111121121111112112211111111111111111111111111111111111111111111111111111---12-----------144----1-1--31-1-14141---31-11--1---2111--1---24858--15324111111111111-6533243713--411142333622423-2131----1241111111111111231------------------------------1122-132255456744222155482222-4A444A56--5562353273716243-1111221111111111-55212--12--212231111132111234411-11222-2121212-1111111-1--1--1321322-12-211112-211112122122---1--2-------112-22111-1---12-121211-2111-1121222554333311111111111111111611-1112--122222222222-------------1-6-3---211-11-1---122222221115-22325533113-3-222111111111-1113333332222212--------1-----2------1--------1------1---1--------1---------1-------1--- 31---1--42-2---24311222553222222211132123112332125234112122111---------1-----------------1524151------1122--2-A433323224154139-51AT8-45421-26344323-2143-7342355-143453--1-57222421512112263B2341152451 * d.80 Tautomerase/MIF
[ 508] ------------------11111---------113--------12321-1731--------------- ----6--2223----------2---1------2-1-6432-1-222131-1-232121--23115-3132111111112-41------435--2--1--21231312-1--------------1121-22--222---111115--11-11-----------1--2-1-1-------------21----1-1299999AAA38AAA995B7746B881-162225444538B12222222222222222242122-----1--22111---1---231111----322-11---1--1--------------41111-111--664ACECADEA5C58J42-111J533-2-2-1C91-111-1------321-5122------2134411132112--1--1------11211112-2--311-22333312111-112-3232-12--------1---11-2-----------2--11--1----------11-1--11112111111-----1131------3-2-----1112--1111--211--1-1124--------------221-3113213222-23----311--1-12-2311---1-----1-------11-----34---2--1111111141-111121-1123----11-------22222213444444454-4446443444444443443454121134434434434444444524222232-333323313222-----2----11-1-1-3----1---------1--1---112-11111134121111-----2212-22121223------5244331123221111111---1441122----1---2-1------------------------------------2-- ----1---2---111--1121112111------1--1111-11----1-1--------------1----------1-----11-------1--------1-2-111--13622-112122323-34-31BA3-4331---32141-2-11-1-522121--1-311--1-112-2---1E21---1341-12--3222- * d.60 Probable bacterial effector-binding domain
[ 509] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3212221-922-56333252444433423343344334442442234455454433322454311112-2-1-2-1--111232113133343564344422524415229KKDMPPCCAABE9cZEg8**a6kOjCBABS8CKBCFFDBHC8bBHDEA254456348448347416A38564624DGO4NE2156661 * g.26 Antifungal protein (AGAFP)
[ 510] ------1211112211--11112--11-----11---1------1-1-11-----------1111--- 11111111111-1111111-11111111111111111111121211-1111111111111111-111111111111111112131323111122221--111111111111111111112222111111111111222-----1122322211-22-11111122122211-22222-22221111111-2242121212222222221111222222213211111111111111111111111112-11------------------121--------------------------------------------------1-12322222222221222211132-11321111122222242111212111311112122112-1--1-1--1-11111111111-111111111111111111111111-11-1211111111111111111-2222211111222221122111111111111222222----13222222222222222222122222222222212222222333322333222322223-------112232121-221-112111222221-132-11-1211122122222212-1111111113-211221211212112222221122211212111---221--1211111-12111111111111-111111111111111111112112121111111111111111121111111-231112111122-221111111222211212----1-111---1112221222111112222--1-11-112-11111111111-1221222221222211111113232222112111----2222222222111111-121111111111211122121233222221111 --21111----13331211-11111111111111111211111122213221121121111122222211322123313322221212223-21-13131131211211257984844333133933434H3-435433153372333223126323434643232433342262-2-2I1123133851441-11121 * b.65 triple barrel
[ 511] ---------------11-------1---1-1-114------------------4-------------- ----611-----1----11-11--4111111-1111-1---6-61-2-23323451-1--7412K25I3B1----1111--11------------------------1-1111111111111121111111111123322---2---1--------------------1-------------12---1-243333333333333333343443333333342222222226411111111111111121111212122111112211222121111112222222222222222222222222222222222222222222233133333333323222223222513322662---12--31-222231331-12331-2222112211111111111111111112-11111121121-111112222111111111112222111--------32212212------------------------------1211111111211215122221112333324122122211223112112111121111111511111111111111-12--112122222-11111111111111111------------------------1114451111111322222222222222222221-1111111-11163333336667686766-6656866666677665666556332336435444544556555455355532-444444434434112-111111111-11213333331333311122222212---2133333434122222322----------3444444443333322222222221111---511111122221222112----1-1-1111111111111111111-1121111122- -----1-----------------1----------1------11-------11---------------------------------------------------1----1------------------------------------------------------2---2----1-----------1---1--------4- * d.94 HPr-like
[ 512] --111111111111111------11111-111111111111111111111111111111111111111 1111111111111111111-111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111131111111111211111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 22111111834122222322222222222122222212122222222222222222222222322222222322233233222221333232222222222224571231324222422C114-7B-J25W7-54C4427822732269252233112222121221422222323333c33323B4392532242223 * d.47 Ribosomal L11/L12e N-terminal domain
[ 513] -------------------------------------------------------------------- --------------------------------1---1------1----1--------1--1-----13---------------------22--1------52241C1-3333333333333336-------------------------11-------1---111----1-------------------2------------1----------11-----11--------2------------------------1111---------------2---111-111-11---------------------------111---1----------------1---------------------2---------Z4----------------1-------------------------------------------------1222-221-1-------------------------------------------------1-211----------------1-----2----11-----1------1--2-1------1-3322221---1---11-2-----1-------------111141-1-----1------5--------1--3------11-2---4DCCC--1BBDC9E4-C-6---2--------------1----------------1-----------------2----2-2-2-22222-2--2----222----22222222222---1----------2--1------------11-----------122222113111--11112----------111--------1------------------2-663356222-2----------------1--------------------------1- 221154D-mKFA236--2211321321222---211-222322121----11-12111---1--1--1-11--1121211-111-1---------4----1-1----4W8DAEEMI598779GAOMBGCY*E3HAJ4967A8AE827345D65E8B88C543566356444--5A1645T2414768762681H38639 * b.76 open-sided beta-meander
[ 514] -------1----------------------------1------------------1------------ 1----------1-------------------------------------------------------1---------------------------------------------------1111-----1---1---------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------1-----------------------1--------------------------------------------1--1-11------------------------------------1-----------------------------------1-------------------------------------------------------------------1----------------------------------------------------------11-3----------------------------------------------1----------------------1----------------------------------------- 1-11664-3158--112232112222121-2321--11-1--1111-11214113321422211----------1--------11111314-21121121111213-479ODJBF8OILLGKJMqVHQMp*O-UQjDMKIQIDNDFKMKBPK8mIQEHLFGBCF311-211NP71124-1113--7A6C2A51213256 * d.83 Aha1/BPI domain-like
[ 515] ------1211122121--------43353324--2------------111211--------2------ 21121-11222----11----2--11-----11111111112-31----1111111-1----1-1-11221-----------1---11--------1---143324252--------------11111111112134433---1233322233333333444343323531--2122-21-2---111---1-1111111--111211-1--1-11------331111111--11111111111111-111-1-------------------211------1-----------------1111111112111---11--------11------------------1-------1---1---11---------1141222------1122--111111----------1-11221-12-2111221-1-221--2113233-3333322111111113111--21--------1--1--11-------------122-112----1111112111133111111112211111121213221111-11-112-1132111-1111----11111-1211-12111----1-1--11--11-111-------------------11-1---221441134342222213-222212--2-2----112-1-111-1121111111111111-1111111111111111111111211-111111111111111111111111111223224423222--1111-112122-1322----1----------11111-111111112121212212222323221132221221-44444543221122222222-111--1-11--11----------1---------1---111---------1-1--------1-- 3211-231522-11-444421121311------2323-1-11-1--33343333533--222-11-11----2--111112--------222421---13254113-4B3DDA98F62242323465417D314453343353334443442532965A3622569566423-F4B777j63678B69B4DB6655652 * c.28 Cryptochrome/photolyase, N-terminal domain
[ 516] -------------------------------1------------------------------------ --------------------------------------------------------------1------1----------------------------------1-----111111--------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------1---1-----------------------------------------------------------------------------------------------------------------------------------------------------1---1-----------------------------------------1----------------------------------------------------11----------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2----------- 11----1-3-1244322322324231233122321212222122224423222312133132222-12-2-122322222-2222323247223232222-3-2211221WCIDCOLDDEHBEA*ZBKDn*S-LMSE8EDOBEO1BEEDCMCFPEZHETb*f5ZX88EC8D4552-11-1-----22592D---1-11- * g.52 Inhibitor of apoptosis (IAP) repeat
[ 517] --171--11---11---11---1-5112181---------------11---1-----12-21----5- 357--1------1-1----------------------11--4-1-611-22-121111-----141223511----11---21-----6473-611----7--1A23-1--------------1------1----28765---81--2----1----1-11----1--2-------------11111----1--2-121--121-12-1111----31111-11------14-----------------------------------------------------------1---1-11---------------------------11111111-1-1-11111---2--2-----------2-----1---1-63221-1-----2--11---1--111-1-1111----------111-322233322231--1-2-------41---------211-1-1----11------1-----------------1111---11---1132-1AAA8111-755179221113---21-221111212111111---12-------1-111113141-1--11-----21-1--3-2332ME12---1---111----------1------11--3F31---3212134233323442133---1-14------111111-1111111111-11111111111111111111111112211111111111111111-111111--111111111211------1------21421-----------------------21-51121213313334-545----------22222222222-22114444433311111-2-------------1-------------1---------------1--11-----1471 534677N1A1---11244463423533----------212211---324368FB6522111125723--1A541974-95-22215--11124431153-13-12--63386555B6547226496274AO6-85F344-5356223422B32E4546721-33426-12234F4-5712211612--2113-1-A647 * f.11 Anthrax protective antigen
[ 518] ----1------------------11--1-1-----111222212212211121--11-1-1-----12 -11-111111111-11111-12112211111-2222124512123--1-221122111--111221352211111111-1-121-1111122-211---1411121312--------------111111111111111112221-2121222--111---11-211112-------------233----1-11222222222222222--11112222322-213333333322222222222222232232--1-23-11111111222--1-122233321112112222222222211111111111112212221112--121222222212112222222--1-1-111-11121---11----11-1-1222------224321-12212211111111111-22423423151-32213343431322111---1-11--122222222-2222322------------1-11-1111-11------11221111-1222222221112222222211222343412322231114121313321-111---------121121221-111121221-222222112112112112----11111-111111111-111-11222--1-121222222232222222212111--1--1------23222222222222222-2222222222222222222333222212222222222232222422222221122222222222211-1-----2222-221311111111111111122222221112233333443-33321433-----1---2----11111-1-1111222222221111--1-11--11-----------------------------1-------111111111-111 ----23--1---1234333544456553322334333323234333243333334433332334322113223536313323333322236335352453141675-3-2-----2------------------------1--------------------------3--------122------1--13----65572 * d.328 CorA soluble domain-like
[ 519] --------------------------------------------1----------------------- -2----1---------------------------------2---2---5--1-2--------2-1-------111---11---2-21121-----------1---1-2-----------------------------------12---------------------1--1--------------------132223236333433323232263335333324322222323----------------11-----------------------------------1------------------------------------23353777557556542335---344--25432243422222222221--2242121-------111------1-------------2--------------1---1------5-2---2122---11111111-------1-------------------------------1222222221211311222222322224232212223--211333433--423222222232-------222142743-43464675563----2224-33-2--2-2335-4576443533333333541---43-534326353855353532363355664---2332------53216222222222222-2412422222224-22112---3222332232323323232323221112212464246485554---------2222--523-------------------------2322323222422223223---------4777566666996774433233224------H54566562222222244--2-----------------------5-23432333-6-- --------3--111111--112-1-1-----1---11-------12---11-12--211----1111--21--1-1-----112-2-11-1-1-------1--4-1---285634242-2-22-4414-9H5-63A1-314445111-317-2837-23-2--112-1-322242----------1--2--1--3---1 * e.32 Phase 1 flagellin
[ 520] 11111111111111121111111111111211111221111111111111211111111111111111 1111211111111211111-111111111111111111111111111111111211111111111121111111111111111111111121122211-111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111133333223232332211111132311112111111111112222222222222232221211111111121111111121111112221111211211212221211111111111111211111111111111111111111111111222111111121111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111121111111111111111111111111111111111111111121111111111111111111111111111111111111222111111111111111111111111111111111111111211111111112111111111111111111-211111111111111111111111111111111 1111111-3111112112112221211111111111121222212221112142111212324322221221222221232222222221511121111112122411413322324222222255372GM2-7442131522342222122233231122512111122211112434d33323488825C3312221 * f.41 Preprotein translocase SecY subunit
[ 521] ------1111111111--------43345324--2------------1-1111--------1------ 21121-11111----11----2--11-----12222111112-13----2311211-2----1-1-11321-----------1---12--1-----1---143323252--------------111121111-1133433---1144332233433444444334423433--3344-43-4---111---1-1111112--211221----1111------231111111--11111111111111-111-1-------------------11-------1-----------------1111211111111-----------21----------------------------1-------21---------1241221------1132--111111----------1-11211-23-111-221-1-111--2113244-3333331111111114112--31--------1--1--11-------------332-113----11111121111331111111212111112311-4221111-11-112-1232111-1111----2111211211-11111----1-1-11111111111-------------------11-----221341134342222213-222212--3-2----212-1-111-1111111111111111-111111111111111111111221--111111111111111111111111111111111111111--1111-112122-1323---------------11111-111111111121212212222223231132121221-44444433221222222222------1122--11----------1---------1---------------1-1-1------1-- 11---23-6221---444611122221------111----------323343333331-232-22-11----1--212112--1-1--1242411----3244121-2H4AGBBDE33121232333527G314342222212322222223264956711--45566451-3B5B686m84678A8AB4977946556 * a.99 Cryptochrome/photolyase FAD-binding domain
[ 522] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 41----C-MAHD58B22121111------1111111-11111--1121221--1121-1111222222122111222222222212122-1121111111111456-3A9WKLMFLGCB8AEICbLASE**S-PLUDDBCRDISFCJAB6FB6PCGAJF9IIIKL34K88B58OF165AY333235-21117119ECC5 * a.31 Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
[ 523] --------------------1---1---11----1---------1--1-1--------1-1------- 11322---------12211-12--23111111322211111221-1--1-----1-----11311123411---------112111131121-211----11--21111--------------1---1-211-2122222343111111111--11------11--11--------------11111441----------------------------------111111----------------------1---------------------------------------------------------------------187-446656763432366111-4132241123334636471222121113--111111111233221133333311111111111-33333433221122223332223333112222444422311111111322-241111111111111111111111111111111212211221122222222222222222222222233444123313312222233233422421411111111134541421511123111--343243295111111751--1---------------------112251213111212111111111112111131-1334212122233222222332222242-3223332323324222224333222323343434344434334222222242-32222222222211221111111116122211111121111111111111111113122222211322222111111111111211121111111221111111111111112223112211--------1-1-------------------------43344444442311 ----111-211111211111112111122122111213232221113211223222121222111----1--111------1111111112111111221121213-113116221-111-111111114A1-112--1111111-111-11-11311111111112411311211111H1112131342111131111 * c.142 Nqo1 FMN-binding domain-like
[ 524] ------------------------------1--------------------1---------------- --1---21--1----2--------1-----------1--1---1----1--1-----1--21-11---2------2--1---------21----------6---512-----------------1-------------11-1-1-2-3-----------1-----1-12-------------2-------5------------------------11-1-----2-----1--1----111-1111-2---1----------2--22----1---12211-2-4---------11---168766-334-253-11---111-11--4-1-----3211121-311-2321-------31-1----1------2-11----1---112----------12221231223------211-2-2-227-2-1----2----2112-11121222222221111-1--------------------1---------1-111-151--3H78C98E88888558GFFF4EE947372--41B2-H-16---9-------37334----1----3A--1---142-12-1-212124122----3U-1-1----1--11-3----------1-2-313152----2-----111----------1----41-------18-6112-554-44643142-3--4226544---3-143364JH6-71222-2224111244-1-11132-2BB99AB79AA7--6----------1-435----3--21-1221-5464556---21BD8BA6A344634-859----------334134334222321-14244HGHDF3F--------1------1----1-------------------------------------1- 71------1----1------------1--------1--------11---1---21-1---------------------------------1--------1-11-------5--1-1--------36-1--1-------------1-------12----D---116---1-2--7------------14--1--211--- * b.108 Triple-stranded beta-helix
[ 525] ---41-----------2--1----1-------112372-----41222112229111-1-1---31-- ---------------------------------------1-1-----------1------1--------1------------1111-1-----1-------1------------------------------1--34422---3-832422155--------3241-11---------------1--1---1111111111111111121111111111111111111112----------------------111111111111111111-111-----------11------------------------1---------121121111111-1---111---211--1--2-----1-11----21-1-----22---------12---11111------------1-111----------1--------11-11212222222---------1-----11-------------------------------31-------1111121111111221111-1221-413--22214-1---1--2------------------1421-231-1-122---1--42751221322232-----------------------1---21---1-22-2--------11-----1-1-31-----11--------------------------------------------------------------------------------------------------2221--212-------------------------2-1111111221211-212----------111-1111111111----------------1-------------------------------------------1-111-2--1-1-- 3423338-723455433333333333454332333314345454333344333224333333343334333433354245433343333443333334333423362344O6BA75C5754573A96B6Ha9-97D4755946A846676775A7557899E3GBB7C8BEACCA4763F2323376A55433323337 * d.278 Ligand-binding domain in the NO signalling and Golgi transport
[ 526] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112121111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111-111112111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 211111215211222132222222222223333222342232222242223222222222222222321223222323232222223432323324423322243512314332335222-322422622K2-2242222222222231222112242423422231326522223331I1112165AI2551111321 * a.75 Ribosomal protein S7
[ 527] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111-1111111111111111111111111111111111111111111111111111111111111111-11-111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 2311111173312222222222222222222222222222222222222122222222221221222212232223333322222233334222222222222336113133222323122322252648U4-6281126422211212222122222244133222234212223241H11122868H2631112111 * b.39 Ribosomal protein L14
[ 528] 11----------------1----122222222--1-1------111112322221111-1-------- 112--------------11-11----11111--111----11----1----------------------1------------11-11-2112111111111111111111111111111111111211111-11111111111121111111111111111111111-1111111111111111-11111111111111111111111111121111111111111111111111111111111111111112111111111111111111111-1111111111111-1111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111112111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111211--111112-12221121111211111111111111111111111111121111111111111111111111-------------------1-11-111211111111111111111111111111111-1111111-11111111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--11111111111111111111111111-111111111111111111111111-1111111111111111111111111111111111111111111111--1111111111111111111-------------------------11111111111111 2211334-52212233333944454544444444444434444544233322333333333343244423443334313443334333334334333333233332144142445323313232671524O3-3461323333311332242133853323313221211111533246D4423454583452233231 * d.75 MutS N-terminal domain-like
[ 529] 11111111111111111111111111111111111111111111111111-11111111111111111 1111111111111111111-11111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111112221111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111-121111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111121222222121111111111111111111111111111111111-------11111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 442223228222223222232222222222222322222212222222222222122222122222321221222222322222222223422222222322221322434232224112222244262BJ3-5222232222221222121222232332132242332222223232I2222354752732214221 * d.181 Insert subdomain of RNA polymerase alpha subunit
[ 530] -------------------------------------------1------------1----------- ------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------1----------------------1----------------------------------------------1-----------------------------------------------------111-----------------------------------------------------------------------------------------------------------------1-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1-21df2---1----1-1--11-21-2--------------11----B121-11--12----------------1--------1------2--3111---1--21--A1AGIICGHN99999J8LB3TEz*T-ROf6D8AJABNH4DC6AG87L9D8EB8TL8Bn99JDG8GTCN-424e212446CKC-64--6AAH- * a.64 Saposin-like
[ 531] 11111111111111111111111111111111111111111112212111221111111111111-11 1121111111111111111-11111111111111111211111111111111111111111111111121111111111111111111111111111--211113111111111111111111111111111111111111111111711111111111121111111111111111111111111111111111111-111111111111111111111111111111111122212222222222111111111121111111-1111111121111112111111111111111111111111111111111111111111111111111111111111111111111212112121111111111111111111211111111131111111111111111111-1111112111111111111111111111111111111111111111112211111111111111111-------------111111111111111111111122221111222312111213211111121111231211121111211111111111111121111111111111111121111112111111111111111111111121111111111111111111111111111111111111111-1111111111111111111111111111-111111111111111111111111111111111111111111111111111111121122221111111111111111112111111111111111111111111211111111111111111111111111111111111111111111111112111111111111111111111111111111111-1-121111111121111111112111111111111 1111121-53511111141111111121111221112222211111121112142122111111112211121111111111111111122112122112141234118122233122212222242515H4-3263232311632122212252122212-32213222221111622O21234A6671444642432 * c.86 Phosphoglycerate kinase
[ 532] -------------------------------------------------------------------- 1111------------------------------------1---1---1--1-1--------1-1------------------12222-------------------1-111111111111111--------------------1---------------------------------------------232111111-11111111332222111333223311111122------------------------------------------------------------------------------------------22222222222222221222---212--12432222222221211121--12122211----114112222322311111111111-2222212212111111123111111-1111112222111--------1111-242--------------------------------111233324333543444233225556252323222--112112111--131122222252-------222122123-2211111222222322222222123-2-2222-2222222222221222221---13-222122212423242322232233332---121211111121122141331111112-3212221111313111111---2232233233333333333331111211241344444334343--2------2222--522-------------------------2233232223422222343---------2111211111341111122222223------222222221111121222--------------------------2-22222222-1-- ----21--------------------------------------------------------------------1---------------------1-------------4EA48586576554PE5I5Y*E-LB765348466557552B45H596781-13323-61243623-------------1---------- * d.367 EscU C-terminal domain-like
[ 533] 11111111111111111121111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111211111111111111111111121111111111111222111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 3411222-72112222221122222222222222221222222222212222222222222222222212212222212222222222223222222222222222126242422222221222332325G312332221222322214232222322122322222223922323233F3323343452732343332 * c.20 Initiation factor IF2/eIF5b, domain 3
[ 534] 222231222222222223333333322422222-2223433332424621232122222322222--- 1111232333321322222-2211222222222222333311111222211-3323-2--22122222222--------224111111------------1-11111-1---------------1111111111132241---221111111111111111111111111------------1111121-1-13333332313333332111113322111--111111111111111111111111111111------1---11-1-------------------------------------------------------2352122222221211111-2221---14-122432226243322-22--1212111-----325215141111111111111111-54445556411-2111111111512112131221223232222222211111221-----------------------------11111-1222233434322222332222222232233321222222222222222222111111----------221-2244222423222-3133313142222224422222222222-2111111122222112212111-1-12222212222222222222----111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1------11-111211-111111111111112121111111122221221111111111---------2222222222222221122222223----111111-----------------------------------------13---2---11-- ----111-1---12111112221313121-21111111111111111121122212221222-------1-------------------1211122-1--1-1111-1--3132312111111122121372122311113121111-11311313212117131112111221112118-111122-31113111121 * b.103 MoeA N-terminal region -like
[ 535] 11-1----------1--1-1-----------------------------------11-1-1------- ----1---------21233-3---1232333-----3-21---1-----11---------111--32111-----------11-----1112--11---1--------1------------------------1-11-1-------11-1111111111211-1-11--1111111111111--------1--111111-1-111111------11---1-----111-----222122122222221-----------------------1---1-1--------------1--1-11-----1---11--1-----------1-11111111111-1--1111---11-11--11-------------1---11221111112112111111121------------2222212113112112212222221111112121222221111111111111111111111111211112211111111111111112211111311212111111222122221123211-------111------11-------1-1111111-----------11--------1-----1---------1-----11212-----------------111---1-1-11111112111111111121---121-------1----1------------------------------1-----1--------------------------------------------11111------14----------------11111--111------2212-1111-111111111111-21121111112111-----------------1------1111111111---------------------------------------1 1122111-5211324135133238879222242323143333422243135AE933632322224353323342344224232322223442342364522463241224569887E6366586DA4H4VsA1C694695A57794675673-C568764A216355446B54622221J21212555766A1135532 * b.19 Viral protein domain
[ 536] -------------------------------------------------------------------- --------------------------------------------1---------------------------------------------1------------------------------------------1------------------------------------------------------------------------------------------111112----------------------11-1111-111----111-----11111111111111111111111111111111111111111111111------------------------------11---------------------111111111111111111111111111111111-11111111111111111111111111111111111111111111111111-131111111111111111111111111111112-1111111111111111111111111111111111111111111111111211111111111111111111111111----1---3-----------2----1----1--------------------------11111112311111111111111111311121--111111--11111111111111111111-1111111111111111111111111111111111111111111111111111-111111111111-111111111111111111111111111111111111111111111111111211111111122222222211561111111111111111111111111--2-------------------------------------------1------------- ------5-------------------------1---1-----------11-----------------------------------------1-11---------------69LSIQHA8A988AGJ3LBp*j3nHK7899I6ED9879C4I34I5GC6O23435652D52J3271----------1--2-1-------- * d.33 SecB-like
[ 537] --1-22111111111112-----1211--111--1--------13121-1111-1-111111111111 --11311111131212233-3111123333311111111112111111-111--11-2--11112231212111111---1-1112-1--------1---11--31---11111111111111112--1---12-1--11111-1---122-1-11----------1-1--------------1-----------------------------1----------------1--1111111111111------1-211111-111211111-111-1----------22---------------------------------1---11-----------1--------1------------1-----------2-2---1-----11---1111---1------------22222121-1--122-22211111-------1-------22222222111---1------------1111111111-11------1-2--122212111122222311522222222122321--221-11111-111-112----12--111--112211-12--1-1-1----1121-1-21-1111121-1----------1-1111111--1122211--112-----1221--3111--23---1---112-------12112-12112222312-112211211322122222132311---2121222222212112211122121----------------------222211321111112--------1-----------1-----11-11111---------------22-111111111111111111111111------1111--------------------1-2-1112----21111-1-------11-- 22--242-411-1134497599667674433331113333233333543344545693233322222212232231313322322211157547634322182425-141O237131443343392464AW91745233354343-444233233224544574465A4C44831---21---238F7C77N--3241- * b.17 PEBP-like
[ 538] -------------------------------------------------------------------- -------------------------1-------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------1--111111111-11--11----------------------------------------------------------------------------------------------1-----------------------------6--2111-19149731415112--11--111-6-365427152E-1G994BC5ECK6E98-1214542562362222222257731223-----------------------------1-143158646GDEKMDA5677DDCJ667768L9D3DA7--54754522I46582242112451-------11--222----------11-------------1117---------------------------1155431-714321444223142213-2-211-------------3413-422111321112-12322-12311123323326757512-2123222222222232G2-222311-322232222333----------1-2--618---436-----111-878792111241EE7E66473585A3555221211222-276643443683217941211------------------------------------------------------------------- -------------------11111111-------------------1-111--------111------------------------------------------------------------------------------------------------------------1121----------11--6---------- * b.149 Beta-galactosidase LacA, domain 3
[ 539] ------1---1----1---------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------- 1-22CA3-42----2------------22--------------------1------1-----111211-11-11-1121--11112111-----11------1221-4K5WUVOLXLDDEDGKEdTAXF**XAVOaFHFAUCIMHAJGEALABdEHEHN5BBBDB83A5765C88----------2343-22-111117 * d.289 WWE domain
[ 540] 111-112122222223-21111114112-223-----------142---11-------241111---- 23618--211----13222-21--2412221232221134-41214---31-343--3--313-1-45441---------A5411133--1---------1--1314------------------1--1------3333311-514223222-3--1-----1--22342------------64333--11-1----------1-1----11-2---111----------22-----------------------------------------------------------------------------------------------------------------------------8--B-2---------3-23111-----146355223223322222222224-6754784812--22233444454447--14142322323--------53311221-----------------------------11132-111134444534222222563333344374342132233422133612143-1-2262-----------24-11--------------11-1-4-443532-12----222212---------11--3--44-1112-2-11312211211111222112----1-2------11212221112122111-11-111111111111111133311---12111211111111125-11---1--111111111111-------------2-3231111--1-----111----------1-33431123111111222---------1-1123333313322--11111111------1---------------1---------------------------------1---11-- ----11------11335533333758333333333322111224332244355634333333--------1-----------------14825213----6-2211-142412111-1111-111121-443-111111111111-1111111-1--11--313111112-23612223O3333365863323244334 * d.176 Oxidoreductase molybdopterin-binding domain
[ 541] -----------------------1-----1------------------1------1-111-111---- 2221311111111111122-2211222222223222224511111-111111-211111122312234311----1-----13111111111-111---111122112111111111111111111111111111122--11111111111212111121111111111211111111111111111---1111111121311112112111211111111111------1311111111111111111111--1----1---1111----111-111111-------11111111111-----------------------11-11111111111111111111-1111-1111111111211111-1-11111-111111111122211111111-1111111111-11311311111-11111211111122111222222222211111111211112221111111111---------------211212442211111233224333332222333313332444311111511111121212211213212222222111221212111111111111212311111332333112222222222222222222222222112232223122222222222222222222221-1111111-11111111111111111111-1111111111111111111111112211111111111111111111111111111111111121111121111122222123111111111111111122222222223222223333333332333111111111122242222233233222222222222221111111111----------1----------------1--------11-111-1111112 ------1-----2212323222333332222222222222222222222223331322222221132221311312222241112122224232233332233233-14--------------1---------------------1------------11---1-----1-----1222N2212114463322264443 * c.144 RibA-like
[ 542] ------------------------1--11---111--------121-211111--------------- 23312---11-1--12211-11111111111112221232-43312-11111112112--221112312121111111-1133-111-2223-1111--12122213-21222222--------22211111121111111111-142322322111222321322213412312112311122-3211-31-111112122212221-111--1211313-11-------11--------------11111--111111---111112---121--------------1-------------------------------11--11-------1----11-11112-11-113132----1-1-11--1--2-31111-2212131121111111111-11111112-11113311121-32211221111112111113323311-1111111122111122111---------------1-----------1-121122133442343344421216555253215422--2233212212112111212112111111113122121---2112--1111-1-1123-----2-24--1111122222112111111111-1122222133111-311111-1-111111--1--1-22111------11122121222133332-2112112213232111112322223321321321122212111111111121-154545554443---1111112222121221---11---------33322321214145443232441333321---------11111222221211111111111221111--1-111122---1---1--1----1--1---------1-------1-1232-1321232 11--332-11-112-----1--------1-----1------1-1-1----1-----1-11111-------------------1--1----31--------11-121--7-44433212121222421628O3-4351111312231222111151233332-24142C222123321925533535657-535311--2 * d.322 PHP14-like
[ 543] --1-1-1--------1111112--111----1---1--------1--11--------1--11--1--- -1-11-------11-------1---2-------111-132111122-1-21111122-11--2-112112--1-----11--1--1--11-1-2--2------1--1---------111111111--1111--1-1-------11---223-11----------122111------------1221111-111-----------------11-1----121---11111112--------------------2111--11111--11--1-111111111111111111111-111111111111111111111111111111-11-111-1112121----1112--11111-222111112-221-1111-1-2111---1--1-21-1111222----------1-113-3412-1111--3----1---2111--213233223-----------1-221--------------------------------1---1122211111-11111112111111111323321112121211--1111-2-1-11---11111-12113-21-11-1---22112-231-12111-12121-1111111111------------11222231221--111111121----11---1----1111211111132222322223233322-222223322223222222222222224332333333333333332222222212222222222221111-----1111111-1111111111111111----------611121323322243221211111111112222222221222321212111221111112-112222111-1--1----1----1--1111---1-1--1----21111-11112-- 11--111-32122121-2122113232121213222222222232211112122221212121--1-111211-122-121111111---74-341---121-453138262522626131525273628U6-43733115421212332116443111222221-43-361-314882a--144D8DA1649264896 * b.58 PK beta-barrel domain-like
[ 544] -------------------------------------------------------------------- ----2---111----1111-11112-1111111---1111-111-------------1--11--21--12---------111------11--11-11-----11--1-1--------------11111111111111111---2-1111111111111111111111111111111111111----------1---------------1111-1-------111-1111112-------------------------------------------------------------------------------------------111111111111111111-1111111--111-11111--1-------1-------------1111111-11111------------11111121-1--1--1111-1-111-----------1--111111111111111111111111111111111111111111111---1--111111111111111111111111111111111--11111111111111111121111-------1111111-111111111111-111111111----21--1111111111111111111111-11111111111111111111111111111111111--111111111111111111111111111-1111111111111111111111111111111111111111111111111-111111111111111--1111111111111111111111-11111111111-11111111111111111111111111111-11111111111111111111111111111111111111111221111111111----------------------------1--------11- 44223331DJ3222211111111111211112111111112111-111111111111-1111111111111111122222111111111322122222222115451364867545731963445G594D*5-B97444654446254254326454455BE353S3346633442434*44433B7GD1964543335 * d.271 HSP90 C-terminal domain
[ 545] ----1----------1--111-------------1-----1--11-2--1-13----111-1------ --2-----111---211----------------------1------------------------------------------------1111-1--1---1-11211-2---------------21------------------14-11--1-----------1-19B93-----------------22----111112111111221------111--------1111--------------------------------------------1----1-------1------1-----------------------------1-2-111111111-1-112222-11-----1----11---1---------1-1-----------11-----------------------------1---11--1------1-111-------------------111----------------------------------1-1-2-------------------1-----------1-----1--------1----1----1-------------1------12---1--------------1----4--------------------1---------111--11-1----1----------------------------------11------------------------------------------------------------------------------1---1111-12-----------------------------2222-----1------------------111--------1-1111111111--------111122-------------------1----------------11---11111---1 421122319532564C9A98989DCBC6777977875957687787998C89988889CCAB656777526544555565556556456674988E654422364612D-3423332231221154-423E3-215121351131131225125-5211---2-221---4-1141273j46441ODG*8aC33A7BC5 * a.124 Phospholipase C/P1 nuclease
[ 546] ------------------1------------------------------1----1------------- 3331423333321344534-341144333334444444441412743334344443231132423254442-----------3-------2--1------1-1-2-212--------------1-----------11-1111111211111111111111211111111211121111121111111---111111111111111111211111111111111111111122111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111---1---------------1---1--1-1--113312111111-------3-21111111111111121111111111111111-1-1111111111111111111111111111111111111111111111111111211111-1111----1-1111111-11-1111111111111111111111111111111111111111111111111121111111111111111111111111112111---111111122112221113113333111--------------------------221111111111111111111111111111111-11112------22112222222222222-1222222223222222221222221112222222222222222222222221-111111111111---1-----111111221111111111111111-1111111111111211111111112211111112111121111111111111212222221122221111----------------111111-1111111111112111111-----------2-2 ------1---2---1111111112121221111111111111111111111111112221111121---1--1-1------1111----111111-21111--111-16-65233322233332563648M4-649134344465133214316355231331352-212322111212G111-2423112122----2 * b.113 N-terminal domain of MutM-like DNA repair proteins
[ 547] ---------------1----------------------------1------2---------------- --------------------------------1-----------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------1------------------------------------------------1------------------------------------------------------1111111121---------1---------------------------------------1-------------------------1------------------------------------------------------------------------------------------------------------------------------1--------------------1---------------------------------------------------------------------1-----------------------------------------------------------------------------------11-1-------------------------111111-11-1----------------------------------------------11-1--------------------------------11----------------------------------------------------------------------------- 1-11123-B31322222212222232222122222422-21322221232225234324223233643235723333545444435655596256E5332262B8I23-5BKNGIJFC8A9B9BRT8KAZ*J3MCV9999L8CBC89A66C99JBFADB58CB6668R8CEHA552--1N-2-12H5662531121-14 * e.46 Virulence-associated V antigen
[ 548] -------------------------------------------------------------------- 3332-1----------------------------------2---1---2----2--------2-2------------------22433-------------------2-111111121111112--------------------2--------------------1------------------------222224244444444444222222444222222244444422------------------------------------------------------------------------------------------24122222222222223222---222--32222224432223322222--22432332----226233333533511221221222-5555535533323222334222222-3432124444222--------2222-263------------------------------1-222232325334653444244325557262433222--223223222--242222222272-------222-22222-2221222222422222222233132-2-3333-33333333333333333331--25-222222222422252422242244442---222222122242232252332222233-2523422222325-22--2---3343344444444444444442231322372466666536565--2------2222--622-------------------------2233232223522222353---------2222422222562222233333335------233333332222222222--------------------------2-22222122-2-- --------21-----1----------------------------------------------------------------------------------------------------------------------------------------------2----------------------1------2---------- * b.139 Surface presentation of antigens (SPOA)
[ 549] ------------------------11112121-----------1111111111--------------- 111-------------------------------------------------------------------------------21-11-111111111--111122111111111111111111111111111111111111111211111111111------11111111------------111111111111111111111111111111111111111111111111111111111-11-1111111211111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111122112111111211111111111111111111111111111111111111111111111112112-11111111111111111111111111111111111111--11111112111111111111111111111111111111111111111111111111111111111111-1-----------------------11111-111111111111111111111111111-1111111-11111111111111111111-1111111111111-11111111111111111111111111111111111111-111111111111--3-111111211111111111-11-1--11111111111---111111111111111121111111111111111111111111111111111111111--1111111111111111-11-------------------------11111111111111 1211222-41213322222232222222222222221333233222232222222322222222232222222222212232222211113222222222232121131159533263323253872B2Ck6198B3253C246444434525934433374234333143414333227222122112221-222223 * d.292 DNA mismatch repair protein MutL
[ 550] 111-11----------1122211------1------------1------1----1212112---1--- -11-2------------11-1----111111-------1-1----12-111-211-------111------2111-11----1-----2242--------1-111-3-2------------------------1---------1---1---1--111-1-1----------------1----112--33-111----1-----1---1212211----1111---111---2-121111111111111-----11----1--111111-1-111--------------11111111111-----------------------1--21----------1----11-1----1----11--1-2---111211----------------------1-1------------------2-----------1-111-1-----12-----2-1---------11-----------------11--11111-11-------------------1--1----11-------1---1111--1--11---------------------------------2----------1--1------1----12---1----------11-------1---1-112--1---------1---11111---2-------1-------2112-112222222222-2212222222222222221322111--2222222222122222121212211-111111111111------------------1111-1-1111111----1---11-11--------1------------1--1------------1--1111-1-1--1------------------------------------------1------------12222-11- ----612-1-2-1-H1-216-----111121111321121222-11MF----1-121M1---11-----511-1--2-3211-212--BK11---22--9-1-12*--5-21124171111222911B1BN5161712224125123-2452443432-13--3-2N---1-261--1--11-2-15B-14---6Fx*1 * c.85 FucI/AraA N-terminal and middle domains
[ 551] --------1--13-31-1-----1-----------11-11111------------1------------ 111-1-1-------12111-1-221-1111111---11111-----------------------111---11-------1112211--112111--1--1111111211--------------111111111121-----111-21111111111111111111111111111111111111---11--1111111111111111111121111211211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111-1--121121111111111--21-11121111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111121111111111112122111111111-1111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111221111112111111111111-1-------1111111111-111111111111111111111111111-1111111-11111111111111111-11-1111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111211111112111111111111111111121111121221111111111111111112111111----------1------11111111111111111111111131211---1 11--111-41--112111-11111112111111112111111111111111111-11112111121111111111111111111112111-111111111121113-21-38AN574534565374494DT7126755373236245334734A322431FA63113211122123222O2222273342321121111 * a.70 ATPD N-terminal domain-like
[ 552] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111-111111111111-1111111111111111111111111111111111111111111111111-11111-11111111111111111111-111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 11111111422122122212122221222222222212222222222222222222222222222222222222222222222222333232222522222-244511312121112112--2-331211E4-126-11-11-11-11-1-1-11211124111211211111122121E11112832I2731111111 * d.28 Ribosomal protein S19
[ 553] ---------------1----1--1122121111-11111111211213-112121111111------- -12-211122222122222-2222222-22222222222221111211111111111211113111112211111111-1121-----222222222--2222242222111111111111111-------------------221--1---1-------------111-----11------11211111322333334332322442222221323222322211111122122222222222222211112111111111122111121111-1111111111121111111111111111112113111111222111123211111111111113111211-12113--3133254223333341111111----------1----1---1---------------1---1----------11-111--------------------------------------------------------------------111111111111111111121111111111111--11111111111111111-111111111111111122-11111111212121122222221-----1112111111111111111111111111--11111-1111111111111111111111111-1-11111111122112112222222222-22222223222222222222221111122222222222222221223222311111111111111--2------1111111111111111112-122211111111241-111111111111111111----1-1-112221111111211--------------111-------1111111111-----1-1-1111-111111-11111-1----1----112 1--121--54121121132112131--1111111121211221-1131111233122-111111111111121113111111111111112112-11111111213114-6233131225332375171MN3-743231343212324212242212323112222331211-33--2-2----112131--1-11433 * c.135 NIF3 (NGG1p interacting factor 3)-like
[ 554] -------------------------------------------------------------------- ----------------------------------------------------------------------1--------------------------------------------------------------1-------------1----1------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------1--1-----------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------ 11--662-OB9-11222221222222111112211112111112212232333422311233111----1--1-1--------111----4225232221112231-4L6NKZKTTL9999CECOJ8PCj*L2TIbBBC8KDCJB7DAA6G86dDHGDM3CHDI964589D8B65-32-------1121342-23657- * b.14 Calpain large subunit, middle domain (domain III)
[ 555] 11211111111111111112211111111121111111111111111111111122233121111111 --2--12211111111111-1111111111111111-222----2-1--11-2---1---21-1-11---11------11122-----3333-111---211213-111------------------1----11-1111111-1------------32111---------------------111------12222222121122222114222221111112211121114111111111111131111111111111-21111111111111111111111111111111111111111111111111111211111111-11211211212111-1---11111--1-1---11-----1--111--1-2---11-11111-111---1-----12222222221-22322222----1111----11--1------211-1-1-11111111----12-2-----11-----------------------11-11111-11111212111111212111111122232-111122222322121231---1111111111--112-2-1-111-111-------------111111--2321111111112122111112-12--22111-121111222212111111212111--1----------21222112222222222-222232222222222222222133222433243344442423422222222--222222222222---1-----1111--2122221111-1111---22222221124-2223222213333111122212221211222111112311111111111111111-1---------------1-----1----------------------21-21------1-1 --11112-54-211213322333523211111122112222222223221538344131222-12112-11122215111111211-1411233211111322114-2515214132111-12-32-11241-11212--1214--111-1--32111537-17322422-1532-234E2114121114142331112 * c.88 Glutaminase/Asparaginase
[ 556] ----------------1-1---------1-2--------------1---------------------- --1-111-----1------------1-------------------1--1111111--1-----1-121-1------1-41111----------------------------------------------------111221111---1---1----------1-----1-------------112----1-112222222332222224244132212-2132297999A2-12222222222222222212I4126F2242677116745733333354565564446554564665545445344444545552225555-214P2222232725-B221553-2-3-4--1111---1--1-766-1231--1111-1111112211111111111111111111-11111111121-111112233111111111112111111--------22211211------------------------------1111111111111111111111111111111111111111111111111111111111111211111111111111-111-112122222-11111111111111111-------------------------1131----------------------1-----1-11-11------611143-3555375764-4334655654465443444867132226754566875638345544255332-322222222222211---------------3333131----2111----------------------------------------113--------1211111111111111---3----------------1--------1-1------11---------1---------- -1-1--1-211-------2---1-----------1-1---1-----1-----------1--1-------------------------1--2---11---1-1-----1--1-21-23-221-----11-23----2---1-1---1-1-1--1---1--111----3--121-11--1---------1--111------ * c.54 PTS system fructose IIA component-like
[ 557] -------------------------------------------------------------------- ------------------------------------------------------2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4433554-4---64524536666556666664666658666775655555553555544555532221-12112222-2222221136657544447676146547-5639BG8CDDA566AE7NP8H8Y*H1HEQ6897C8ADE8BA97888J6HCAA6DA87744A75D89661243N22343766B5773344443 * a.188 PWI domain
[ 558] --1---11133211-1-------------1-----------------------11--11-1-111--- ---1--11111-1-11111-11--11111111111111111211111-11112111121122-11122111-----------112---111111112111111121121111111111111111-----------11121----2111111122111111111112111111111111111111122---112222222222222222212222222211222233333332233333333333332222323-2-11-3---22112221111211133322221222222212222233333333333331222222222-11112222222121-111----11--11----11---111-1332---11-1111111111111221111212111111111111-1111111121111111111111112111111121221111111111111111--1------------------------------111111---1--------------------------1---------11-----------1----------11----2-1-211-111-----------------11--1----------------------11--2212211211211111111111111111111---11-------33222323333333333-33333333333333333333332323333333333333333334333222321333333333333221-----------1113111212111111111--------11121111111111112112111111111111113222221121111111111111111----112222------1-2-111111-2-22111222121121--1----------1212 22--11--2-----1----1--11-1-1-2----1--11--1-----111-1112----1--------------1--------------221-1-11-11---111--3352-111113321655423-8J7-324452333321332-7223332223-1122-12-11---2-2132B213238537-38121--21 * d.224 SufE/NifU
[ 559] 1112111111111111211111111111111111111111111211111132212223222---2--- 11111211111-1-11111-12--121111113121-222-412-1--211-2-1-------1-21-221-----111-1-21-----11121111---11111-1---------------------------1-11122--12-1111111--11111111131311111111111111111------11112222221212222221111112121111111111111-11111111111111111112111-1111-111----111-----11111111111111111111111111111111111111121111112---1111111112122-1111121111-121--11-----1---------2-11111-----11-221-------------------34233545131-11111222131111-1-1-3--1---1-------------121----------------------------1---1--111-13333332222233222222222222232--223111--11112-12311-11111111111-1111-21111112321111-1----1------11---111-11111--------------11121121-111121222213222222223231---1111------11221111111111111-111111111111111111111122112111111111111111111111111--222222222221---1---------11312111111-1111111111111-11111111112111121211111---------12112111112221111111111111111--21------11111111--1----------------1--------1--1---------- 32--121-843122221211111131111211122321111-12122122211211121111111221112-221322222222121121421111111111233211544335432253211131263EV3-22322132322212331222324334111543324225394351113---12332A2421311111 * d.63 CYTH-like phosphatases
[ 560] 11----1111111111--1-1---31111131---------------------1-------------- 2451111111111123211-171122111111433421111111111111112111111111111121111------------1----11----------122222312--------------11----------11111---12132211111112122232211544211111111211211111---22222222222222222222442222212332111111113211111111111111111111--------------------------------------------------------------1-----------------------------------1---------------------1-3122111111136444312122233333333333-336446344411433265545565211112132222222111111112221221-112111111111111111111111-111111112-1333453332533443333655553344557661155532222213141421322121-------1233141-1---11-1-112-1-1-1111-223223---------------------------111112215122111222321222221122121--32-111111111111111111111111-1211111111111111112111111111111111111111111111-111111111111111111111111111121112111---------------1111111-1-1133332322122222111-11111111-1--4-----221113322222222111111--221111----------------------------------------------22-- -4--1-1-1-----11111-------1111-11111-------212-------1131-----11211---1-----2--------------111--11211--211----1-12411-1-112141-4-2D1-33211--31132-11111-1123-2-12-32-112--n-111112----------4-111-2-112 * f.25 Cytochrome c oxidase subunit III-like
[ 561] -----------------------------------------------1-------------------- --1---------------------11-----1----------------------------------1-----------------------------1---------------------------------1---------------1-------------------2--1--------------------------------11---1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------11111-111-----1111--1------------------------------------1-1-----------1---------------------1--------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------1-1-------------------------------------------------------------------------------------------------1---1-----------------------------------1- 2211CC7-835-21333323333434333333333333333443334333323433543343433333423433343434334323322372362232321335F3193ACFFEJEGAA67AABUF8F9a*B2GCN6879EABE75A797C65K9C88C47477754665A5858-111F21222524733234CEGE6 * a.222 VPS9 domain
[ 562] ---1--1111111111-1111111111111111111111111111111111111-1-111-1----11 1111111111111111111-11111111111111111111111111111111111111--111111111111111111--11111111111111------111111111---------------111111111111111111111221111111111111111111211211111111111111111111111-11-11111111111111111111111111111111111-11111111111111111-1----11-1---11--11----1-111-------111------------------------1----1----11-1111--1-1-1111111---1-1--1111111111111111111--11111111-----111111111111111111111111111111111111-1111111111111111111211111111111111111111111-----------------------------11111122222222222222222232222222224223212222222112111112242111222222222111122-1111111111111-111111121----111111111111111-1-------11111222223233232222222223222232322221-1133211111163333333333333333-3333333333333333333455332233333223222333333333333333-3222322223332211-----111111312222222122-1111233333222212222222434332222222322222222233342222244222223333333322222211111111--------------------------------------1--1-1111211 ------1-----11111121111121111111111111111111111111122211111111111111-1211111111111111111111211221111111111-14----------------------------------------------------------------1-111181111111212111111111 * b.168 HisI-like
[ 563] -------------------------------------------------------------------- ----------------------------------------------------------------------1--------------------------------11--1-1111111111111111-------1-------------1--11------------------1------------------------------------------------------111111---------------------------------------------------------------------1----1--1----1-------------------------------------------------------------3-----------111-1---------------------------------1-------------1111111111-----------2--------------------------------------------------------------------------------------1----------------------122-1------------1-1--1-1114133--------------------------1----------------------------------1-----------------------------1-------------------------1-1--------------------------------1------------------------------------111111111-------------------------------------------23--2-2211------------------------1-----------------------------------112- 5534113-62111-121322222222122222221222222212222322222222231212223222123222333-332222222223221443222122222112C28ECDGH99887BABJG8ICd*G9GDYB787C9BGA6AAB9J99WBB9C92AB54354C56A7E444683544475844H2FA2164444 * d.76 GYF/BRK domain-like
[ 564] ------------------------11121111111--------2211211111--------111--11 1121211111111111111-111111111111111111421232111111111111211111112232111111111111111111111111111111-111111111111111111111111111111111111211111111111222212222111111222133231111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111112111111111111111112222111111111111211111111111111111111311111111121111111111111111111-1111211111112111112111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111122212111111111111111111111111111111111111111111111111111111111111111112122122211111111111111-11-111111111111111111111111-111111111111111111111111111111111111111211111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111----1111111111111 1111111-5211111111-111111111111111111111111111111111111111111111111111111111111111111111112111111111111211--612111-23222122222232352-2341212222312112121232222211111111121111122322G2222244461622211111 * b.73 Head domain of nucleotide exchange factor GrpE
[ 565] -------------------------------------------------------------------- 1111411111111111111-12111111111112133332111121113111111111111112111151111112221111111111112122111-1111111111111111111221111111111111111111111111112111111111111111211132321111111111111111111112233333233234535222222333422312212222224222222222222222222322112111111112222112222111112111111111111111111111222111111111111111111122212222223233212542121212112221211212112112223111111111115112112111122111111111111112-112214312112111111111111211111111111111111111111112111111111111111L11111111111111111111111111111111112111111121111111411111112211212131111111121111232211111112111221111112111122111111121111111111-1111111111111111131111111111111111111111111111111111111-1111111111112113211211121232121131211122211111121112113333122112212212213111223211211111111311111111111111111111111121221--132131122121111112221211121131112111111111111141111111111111121111111111111111111311212211111C111-11121-1111111-1111111121111111121 -------------2----1-----------------------------1---1----2-------------------------------------------1-------1---7---1-------------------------1---1-----------1---3-----------1------------21-1--1---- * a.81 N-terminal domain of DnaB helicase
[ 566] 11111111111111111111111111111112111111121111111111111111-11111-11111 ------------------------------------------------------1---------1-----------------------1111-111---11111111-1--------------1---------------------1111111--1111111111-11111111111111111--------111111111111111111112211111111111122222222111111111111111111111-1-11-1--1111111111---1221111111111111111111111111111111111---------111111111111111111111111111111111--1---1-1-11111-11--1---------------------------------------------------------------------------------------1------------------------------------------------------1-------------------111---1111--------1--------------111-111--1-----111-1111111111---1-------------------11--1--11-111111111111111111111111111-------------11111111221111111-211111111111111111111111111111111111111111111111111--111111111111--1------------1111111111111111-1----------1111111111111111111----------11111111111111----------------111111-1-----1--111111-1---1--11----211--1111-11111111-1-1 3223332192322333345233334333334333332323333333232333331322322232353323332333435333333322238333423334231445-334444444542G43657E3546P5-55964338345454734564D5644443534433343433432334F3332366694763454322 * d.64 eIF1-like
[ 567] -------------------------------1------------------------------------ 1111211111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 22--222-411-11111111111111111211111112222111112111111-11211111111111111111111-1-111111-1--211112211-2-1111-2623322223221232254141BG3-536-2221212322-2-41231222311323211223112332232T3332232252232221111 * b.117 Obg-fold
[ 568] -------------------------------------------------------------------- -------------------------------------------1--------------------1-112----------------------------------------------------------------------------1------------------------------------11------------------------1-----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-1---------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------111---------------------------------------------------------------------------------------------------------------- ----743-211---1--12-22-3-21112111---1111121-11--11111122211333---------------------------------------------355kGIEJCVHBADHMHkOCMGh*I3NKbAGCFPFIPHCHIFCMD7REHFDD7CG34C9CH99B38J61-1--11-1--2-112---211-1 * a.133 Phospholipase A2, PLA2
[ 569] ---1---------------------------1--------------------1--------------- 1-----1----1-1-------1----------1-112-1----1---1---1-----1--111-2-1-11------------------------------1-------------------------1---1-1-----1---------1----1----1---------1--------------------------1-1----------------------11----------------------------------11-----------------------1------------------1--1--11--1------------------------1------------------1-----------------------------11-----11--11-1----------11211112-1-------------1-1--1--11111--1--------------1--------------------------------13-------------1111-----1111-2-2--1-------1--11---------1----1--------------1----1-1----1--1--1111-----211------------1-------------11-1---11-1--------------------1-----1---------------11---111--1--1-1111111--------------------------------11-1111-----------------------------------------------------------------21-------------------------------------2--1111111------1111----------------------------------------------1--- 1144754-LC8135278BD2435533522235462314444553117323756456D79433111111-2112-12111112221211-234886831651C2234-3E2867ACFB96B5758D75B8Hu619955B56495641887778996A67317-2659AFA78578--E9CK444478636978267I478 * a.115 A virus capsid protein alpha-helical domain
[ 570] 11111111111111111111111111111111111111111111111111111111111111111-11 1121111111111111111-11111111111111111111111111111211122111111111111111111111111121111111111111111--11111111111111111111111111111111111111111---1111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111-1111111-111111111111111211111111111111111111111111111111111111111111111111111211111111111111111111111111111111111121111111111111111111111111111111111111111111111-11111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111------1111111111111111-111111111111111111111111111111111 1111222-522111112111111111111111111111111111111121111111212112111111111-111111111111111111112111111211111111431132112112121122111161-1211111121112211111121132112-11111213311212223I2223334371533242322 * a.36 Signal peptide-binding domain
[ 571] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111111 1-1111115221122111211111111111111111111111111111111111111111111111111111111111111111111112211111122112154411212111-11111--2123-2-3D1-1121-11111121111121121211111111111112411123221I1111163981341111111 * d.53 Ribosomal protein S3 C-terminal domain
[ 572] ------------------------------------------------------11-11-1------- --11-1---------11----------------------------1-------------------------2---1111-1-------111-12111--111112-121---------------111111-111121111---121--111-1---------1-----2-------1--------------1---1-111--11111111----121111-1-1111--113-11111111111111-111-1--------------------1-12222211111111222112111111111111111111111111111---------------11----------------------11-----------21111111111111111121111------------11121111121-21111112211111-1-111----2-111111111111-1--1----------------------------1-111-1111111-1111111111111111111111-111--1211121111121111111111---1--11111121------------------211-11-----1--1------------------------11-11-141-1-11----11-----2--1--1--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111-1-111111----11112---1-1------11--------11122------1--------------------1--11111122111----------11-1------------------1-------------------------------------11-2 -31-223--1----267877474878833555533443333334349845899965543322426442246633455344533645645CG87IEGA88938B234-3H2131212121-211-21321181-211-121122321--31433-1212211--31237313----11-4A2331258B962862A8EF3 * e.42 L-A virus major coat protein
[ 573] -----------------------------------------------------1-------------- ------------------------------------1---------------1-1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------- ----972-----544343211114232222-11332211121121133334333233332332-1-1-2-11--21-----111111116C84BDR3333552776-41I7OSLISAD97AAEDNGAKBf*J-MHMBA7ABCAJE6BB99C98GCEADC67B9A772OE8DDG66----------1689353-122112 * a.66 Transducin (alpha subunit), insertion domain
[ 574] 22222222222222222222222243323323111111111112211242343143433331112123 -1----------------------------------11--------------------------------------------------------------------1------------------------111-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------1--1------1---------1------------1----11-----------------1--1-1------------1----------------------------------------------------------------11-1---------------------------------------------------------------------------------------------1------1----------------------------------------1--------111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 56244332C3325544555555564555545455555555555555754457455554454455454534554544434444345444446454444444344477379556966734243454A5372Is7-7662342735535533345354745435655363746B67533522*44447B7JC5B85778863 * d.31 Cdc48 domain 2-like
[ 575] 1111121111111-11111-1111--------------------1------1-11111111---1--- -211111111111111111-1111111111111111121111111----1111-11------11-11----111111--1--1--1111-21--221-------------11111111--------1---------1122---22111-1111-111111-1-1-11111111-11111--1-11--11-1-------12111111111-----1111----11--------1111---1----1---11---1------1--21-------1--11111111111111111111111111111111111111111111111-----1111111-1-1--------1-1----11--1--1-1----12--111-111------1-1-111---1--------------11-11-111-11-112112-1------1-2212222111--------111--11---------11--1----1--1-11---------21-111--11-1-11111--2-1111111-2313111211------2-1-1--------1----------1-1-122-111-11111--1---1-1-1-111--2111--11111-11--------1-11111-1--1--111--1--------------1---11-1-------11111-11111111111-111111111111111111111111---1-11111111111111111111111-111111111111-1------------1--1211---1----1-----1-11-111--1-11-----1--------------------1----------111-1--1111111111---------------1111-111---1--1-----1-------1--11111-1---- 2322313-A44343234436534455565353433343333334553479456334563444322122222122322122222212343485433A232331233523-274532514343364453528J3-4363223423631342144343223333436444433545433442Q2323236855224342334 * a.258 PG0816-like
[ 576] ------------------------53232232-----------43--1-------------------3 12115-1----------11-1----411111-32222-23-313-121123121221211445-815454-2--------312---1-1-11--------11-1--2211111111---1-1-----1--1-1--1211----1-11-----22-1-2-11---1----11---2-2-1--134212--12-3555553673757446133333776111311222232451-22121111111211-12112311112-113221133----1111-354111113322222122222232123223121221-11----3161262221-21-1221113223121-1-1112359322-1-3---11-14-12222-----414232211343133323332333-2652543642--533435525542121--3-2---2-33------------121------11-----------------------3-3-124321443233-121-44331111-12123-111--12122223442112132333--22--1-2-1-231--2-2233131212-1111-1---741355--11--1111111--1--1---11--2112112-11231------2-----------12---1---------2--11122222222222-2232222222222-1211212211112323113333333331311-11112--2--------------1-----11111-21----------------21122-2-1-1-223252431-1---3211-2---------2111111114113341312333------1---3311------------------------------------1-1---1-----11 1---1------------------2-------------111-1-----1-11-2------1-1------1------------------------1-------1------21-----1------------------------------------1----2------11---1---2--11-2-----2--11--2-2---1 * d.123 Sporulation response regulatory protein Spo0B
[ 577] -------------------------------1-------------------1---------------- -----------------------------------------------------------------------1---111-----------------------------1------------------------1-------------1------1----------1---------------1--------------------1----------1-----------11111111------------------------1--------------------------------------------------------------------1-111----1-2--111----12--3--1---2------1-11--------11--------425---4-64-------------43532-21----1-----------1-1--------1------------------5-----------------------------------1----------1--------------------------------------------11-----------11-----------------1--1----1---------5---1--3-1-------16-----1------------------------1---1------1--------------------------------------------------------------------------------------1-----------------1-2--------------------------11--1--2--1111------------------33333-2-------1----------11-------1-----------------------------------1---1----11--- ----7C7-2---44512111112111222323311111111111112111111111221111111---111111111-11-11112111121211111111-1111-7-2DPOITMTC9A8BCBYV9HAI*CAHGI8BCACDCHD4FA6AV87IEQDBB7HN74679588A5884-1-1------111-14-------- * a.216 I/LWEQ domain
[ 578] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -1--2-------1-D---2A-----1---5-------------1-1GH---------H1---C1-1---N11----2-11---3-2--Br14----2--A-5--1*-----424--1---112----411E31111-11-21-2------1--4--B-2-21-3--x----4-11-11------1989J-41--2e**- * a.166 RuBisCo LSMT C-terminal, substrate-binding domain
[ 579] 11111111111111111111111111111111111111111111111112111111111111211-11 1122111111111111111-1122111111111111121111111-11111-211211----11111111111111111-111111111111-111---1--111111---------------111111111112121111111112211111111--111111111121111111111111111111111-----------------1--------121-121------1-----------------------1----1-----11-----1111-----------------------1-11-111-11-1----------1--111111111111111111111111111111111111111111111-11121111-----121112111111111111111111-11111111112-11111111111111112211---1-11111111111111111111111111----------------------11111-11111111111111111121111111211111--1111111111111111111-111-------121111111111121221111111111111111121111111111111121121111111112--1-1111111-111111--111111111111---1111------11111111221111111-121111112211111111121211---11-1111111111111111-1121--111111111111---111111122211112-----1---------11111-1111111111--1-1---112111111111111---11111111-1121111112221111--11441111--------1---------------------------12111111111211 12--111-41112222223222322232222222222323433221222232231222222222222222222223212222222222222222223121221332-1316663234332333135143AR3-449252343255134-3331432224-1144231222411212121811-1111312311132331 * c.104 YjeF N-terminal domain-like
[ 580] ------------------------1-----1--------------------------11--------- --1---11-------1-------------------------111--------1----1---------313-1---------111--------1---11--1-----1----------------------11--1-----------2---------------1------2------------------------11111121111211111--1-111---------1--11---------------------1----------------------------1221------------------------------111-------------------1---------1-------11--1--------------1111------1----21----1---------------1----------1111-1---22------11------1---------1--1-----1-------------1-------------------------------------11111-11-------1-12-----1-------1----2--------1-4--1------------------------1----2----------------------1-----------21-------------------------------1------12----11--------1---------1---------1111-----------------------------1--------------1-----------1-1111---1-----------------11122222232122221222------------------------11-------------------------------1--1--------------------------1--------1- --112-1-1-1-DC4ADGFC464B9957788882115433433666B435GGAC77IIB887-1--1---1---1----11--1-1-1-143DK23-----4212---F3R584745343353344374BL3-97E42335237333333334326345CCF6343B8HOD675-211-----1-G63JE1E2-9DBJX * a.86 Di-copper centre-containing domain
[ 581] ---1-11111111111-1111111111111111111111111111111111111-1-----1111-11 1111111111111111111-11111111111111111111111111111111111111--122121121211111111--11111111111111---11-1-1121111---------------11111111111111111111111121111111111111111111111111111111112111111-11111111122112111211111111111111111111111211111111111111111111----11-1---111111-1-111111111----211-11--1--1---------------111111111111-1111111111111111111-1111-1111145141-11111111--1111111111--1211111111111111111111112-1121111111112222232222112111111111111111111111111111111---11111---------------------11111111111211111111111211222221112111211111111111111111111111111111111112111-111111131111112111112111111112111111111111-1-------1111111121111111111111111111121111211-1-111111111111221111111112111-111111111111111111112122222111111111111111111111111--111111111111---1-----111111111111111111111111111111111111111113111111111111--------111111111111122111111111111111111111122--------1------------1---------------11--111111111 1--1--1-321-22211111111121111111121111111111212221222223111212-11111-2111111111111111111111111121111131112-12-33323231212322542C2CY3-655-1-2322321212-221423312133131122218--11111181111221221121111211 * d.210 Argininosuccinate synthetase, C-terminal domain
[ 582] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1-------------------------------------------------------------------------------------------------------DXURdKbHCCCIJIgsCPEp*MNWKyKHCFNEKIC4ICD9JGBTFKLHI5A638953357F227------------------------- * g.73 CCHHC domain
[ 583] -----------------------------------------------1-------------------- 3452-1-----3----1AB-B2----AABAC-22-21-12-1513--21--111-11---331-3-1223-1-------262---1---------------11----2---------------3-16224-1A1111133-----872243B--222--11-25-8466--------------3143---1-------------------------------1----------222122222222121---1-12-11---1-11---1-1-------1-------1-1111-11-11---------------11---111-24---------------11----------15-54B92581-353321--3---8--1-1--14211241114246-------1--5-2411-141212-21135FEB9C3324--2112-5-----222222221114--64------------73A8-5A56-55--------41------3443722-111222-1111-14121331----2212--353182--83----1--1-111911A21-316--5--1--1-1111122F14-----1-1-1211111111-----------1-266--6712-4-2--3-2--1--113-2--41----1238------12-1-1-2111222311-11211211-11211121122-1538B2121-2211111-2--2311-2222--3111111111----6-2212211----119233------113-1-1-4-2--12-33-----223-2----434----------41246655652131112-2--222--------21--21--------5---------------------------1211-11111---- -----------------------------------------------------------------1------1-------------------------------------------------2--1-------------------------------------------------------1----------------- * d.306 YefM-like
[ 584] 11---------------------15445-524---2--2222212-15-12-2-2-2122-------- 3631------------------------------1-----2---2---2----1--------2-2-------------------1111----------------1--1-------------------1----------------2----11------------------1--------------------343223233333333333343333333333433333333343------------------------------------------------------------------------------------------66355555555535541553---437--57463445537343333342--3112-11-----11211111241141111111111--22322222--1----1--1-----1-1-1---1111-----------1111-621--------------------------------1-1111112221221322222223333132321111--11111222211212111112111-------111-224452544317322216367675462212114-3333-2223112322222225341---44-5224344-4444464344444533444--11112---11111111111111111111-1111111111111-11--1---11111111111111111111111--1111211111111-1111---------11111-412-----------------------2-1211111211211112222---------1555455555554551111111112------B56655542222222243--------------------------4-44444344-4-- -----1--1--------------11---------1--1-11--------1-111--1-1111--------------1111-----------1---2---1----1-----2--1-1---1----1-----2------1----1-----1-----1-1-21------------------1-------11-21----1-1- * d.252 CheC-like
[ 585] ---1--1111111111-11111121--11111222222222222222222222222--------2-11 --22311111111121111-121113111111211123322222122-2111111111--222122322221111111-121222222222222------1--11-221---------------22223333323111222222222212232222111111222222321111111111111112222-21111111111111111111112111111121--11111133-1111111111111111111------------------------1--------11111-1111-----------------111111111-21-22-------1-12122----2-2--211221123222-2211-2--1-221111-----222222223222222222222222-11111111222-2112222222222211122222222121111111111111323-----------------------------211111211111222312-1112222111111212222211222212223121212231212111111111111132-2222222122222-2222222222222-3222111111111--1-------11111222211221-2121111111111111111111---1211--1--111211211111111111-11-1111111111111111222121111111111111111111211111111-11111111111111-----------11122111111-111-111111111111112111211211211112111211-12111211111111111111111111111111111131222222--------------------------------------2--2-222222- --------------11111111111111211-11111111111111111112221111111112222112212122222222222211113312211121111111--1-1--------------------------------------------------------------1-2112H1111121211222221113 * d.270 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
[ 586] --------------1------------------------------1------------------1--- --1-11-1-----111111-11111-11111111111111--1-111-1---------1111--111-1111----1-11111-----11111111----11----1----------------------------1111----1--------------------------------------11111111-11111111111111111-111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111-------------11111111112221111111111112211111111111111-1112212222-2222111-------11111-------------11111111111---------11-1111111111111-----111111--11-------------------1--------------1------1-11-------1--1--1---1------1---------1--------------------------------------------1---1-----------------------1-1----------1-1111111-----1111---1--------------------------1----------------1---------------------------------11--------------------------------------------------11111-2---------------------------1-1-11-------------111111111-------------------------------------11---------11----1---1--------1-------1111111111---1 12--342-4131112113-222222141132411211323333-11211121312322142212112111111112111111111111113412112221121231-56297878886BA6866DB896**8-96D6B688A786679B8A76M8774635642342344F44632235I2226247A51571131122 * c.100 Thiamin pyrophosphokinase, catalytic domain
[ 587] 1-434443444444444446433422222422435224666656425534555255556662444-11 234--------1--1--11-12--21111111222211231221----------------1332112--11-------1233-2322244463344--------1-111---------------2324311421222222222--2111111--11------11--221--1-----1---------222-1-111111111111111-1----1111121---1111111-111111111111111111112----------------------111--------------------------------------------3874422222222225633211143522321532233554867544442114-1112------331111-33534--------------------12--2------11---11--1-1------1111111111-----4-2------------------------------111--1----111113-----1111-----11111311--1112-1---114----41---11----------4-316845455334665265655557644441-56-222222222222222222223222--211---------------1---------211----2-------112111-1111111111-111111111111111111112121---11-111111111111111111111--1111111-1111---------11111-1-----------------11111---------------1-1--1111-------------111111------------111------22--------------21--------------------------5345444344231- ---1111----3---2-11----------------1-111121-------1---112111--------------------1---1---------------1---11----2-11--2-1-2-1---------------1221-2-1------------1----2--1---3-11--12-----1-2--2----1----- * c.64 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
[ 588] -----------------------1---1---------------------------------------- 223-2---------11111-11--1111111111111121-1111111-111111-----111-1132421---------1-------------------2-1-111-1-------------------------------1----------1----------------1---------------------1-111111121111111111111111----11-11-----11----------------11------11--1----11-------------------11------------------------1-----------------1----1-11------1----1--1111-111112112-------11--1-----2262341122222----------2---------241-13324744643532------22221-----------22-----------------------------------1111--11-1111-111----11121111---212211--11---121112-1----11-3-1---------11111----1----111--211---2--112111-1---------------------------------------1-----1-----1----1-----------------------------------------------------13------1----------1---------------------------11111----------------------------------1111111-11111111211--------------------1---1111111-----------------------------------------111--------------------1-1 --11335-623-5442342234233-32222222222232322233322232222232226322232223222222223323222222224332332223332222-235AA9979745543659A4B5J*A1B9K6345667863542463385956759A85634A44B5D54-23132333343842462322324 * b.131 SPOC domain-like
[ 589] -------------------------------------------------------------------- -------------------------------------------1-----------------------------------------------1--------------------------1--------------------------812222111221111111112131111-1111111-1-----------------------------------------------1-----------------------1------------------------------------------------------------------------------------------------------------------------13343-----21543312232231111111-111-11-11-11-14-1212111111112-1331411-11123--------1121-12-------------------------------332311111-2221211----111-1111-122-112113111-11111-1-12112----2-1111111-1------1--------------------------1--------------------1--------11-311133412222222222321213222----11-------11111111111111111-111111111111111111111111111111111111111111111-111111-111111111111---2-----2222-3--1---------------1111111111-12222112222221-111--------------11111111--1111111111--------221111-------------------------------------------------- ----622-----342583341224246333333233111112133334233214111223242----------------1---------33184122223317122-2ABE6B86B48664785DA475IQB-A8D557586776454346746676695543886243351166111281-134411261334A8AE4 * f.56 MAPEG domain-like
[ 590] ------1111111111-12-----11111122---------------------1-------------1 1211111111111111111-12111211111121112111111121111111111111--11113111111111111111111111111111-111---1212212211-------1111111111111111112111211111-11121111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111-111112-----211131111111111111111112-12112121311-11111111111111111111121111111111111221-111111-1111111111111111111111-----21111111-111111112222111122222211111121144121222232421113211111-------1122211111111111113111111111113333422211111-----1---------2111111222112412232333333433333333343--12222------22222222222222122-2222222222222222222222222222222222222222222212222222-213123313222--11222222222211131111-111111111122222221113211112222212224222111111111122232222222322112222222211111111111111111111111-1-------------------------11111111111511 -1--1-------------1--------------------1---111----------2-1-------------------------------------------------3-1------1------------1-----1----------------1---------1--1------1-1211F111213136-1111--211 * d.204 Ribosome binding protein Y (YfiA homologue)
[ 591] ----------------------------1--------------------------------------- --2-----------------------------1-----------1---------------1---------------------------2243-111----2-------------------------------1--1---------------------------1-1---------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------1-------------------1---------------------1----------------------------------------4------------------1-----1----------------------------------------1--------------2--------1------------11-----2--------------------------------------------------------------------------------------11---------9-----------1-------------------------------------------------------1--1-----------------------------------------2---------------------------------------1-11-1-----------------------------------------------------1--------------------------------------------------------- 11--113-956-2121111111111121111111211111111111121111111112111111111111111111111111111122321311111111111212----CGKKQUD78784JAXVAZ9u*U3XDf7985C69C88CB869B2LALB983766AF332527335312211111123ACC1C1112211- * d.25 Mitochondrial glycoprotein MAM33-like
[ 592] -------------------------------------------------------------------- -------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------11111--1-111--1------111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------- 4422554-E54-33623333333333332333333333223223333333333423333333222122212-2222222222222222223435353333223351-572BBD78B978869A7BB7RAS*E3DAM6A67B89C67A947E45JAEA6834L88666966I49741674L44467E77D3W91454541 * a.217 Surp module (SWAP domain)
[ 593] -------------------------------------------------------------------- 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111-1111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111-11111111111111111111111111111111-11111111122121112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111-11111111111111111111111111111 11----1-1---1111111111111111111111111111111111-111112111111111111222112211122122211111111-1211111111111112-1-1212122112--12111-114E2-241----11223211--111121--2131-2111211211233222M1222243281231111111 * d.27 Ribosomal protein S16
[ 594] --------------112-11-1-1-------13142124433322323-23223-------------- 1111121-----1---1---------------1----111---1----1------11---1-111122111----------2-32222224-2211------1122--1-----------------------12-1-111-1--2-11-111----------111111----1---------111-----123333332232323223223332223-22121211111111211111111111111111111---11-------1111-1----1-1-----------------------------------11---1-1-------------1-1--1----11----1--11333311--11-----1---2---1-----1--------1-1----1-1----1-11-11-111------1111111-1-2--1112121111111111111-111-3-1----------------------------------------2112121122111321111112233221--21-----1---1--112241-2311111111-1233-2331223112222-615212-22-----2-4-1-1-11111211111111111-121121411121121-322212122212212111--11--2------21324112222222222-222222322222222122112143113111111111111111111212222------1---1111---11111-----222-1233223211113332----------21-----1--1----31-----------111141111111122----1---------111-111111----------------------------------------------1--1 ----------111-2-11--11-121----------1-1-1--1-----1--2-11-------------1---1------------1-----112-1----1-112---162114495243394A9473Ff61B6C23337346614542655N45443376175D492211225-----1-2--2113--1-----1- * d.174 Nitric oxide (NO) synthase oxygenase domain
[ 595] --------------------------------------------------1----------------- 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122111111111111111111111-111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112221111111111111111-111111111111111111111111111111111 22--111-411-1111111111111111111-111121111111111111111112111111111111-1111112122111111111111111111111121112-1511112111211111-11111161-111111-111211111-11-11112211111111111111212222I2112243441332221112 * d.188 Prokaryotic ribosomal protein L17
[ 596] --1-1-2-1111111113---------2---------1------2--1--111121121--------- 34A4822533322234433-3422253333323333456645743546233153333211225-4495C55-----------1-----11111311---2613333544---------------111211111314556722256--11----1-----------21-3-------------55544---4343333322222233322222222242321112------6311111111111111111111--1---------------------------------12211111-11--------------11---111-1-------1--11-1-311-11---1--51-121--1-2-12122311--3-5----------1121-----12---11-111112-22222222111-122--121-1231-----1--------111111111111-12-------------------------------1-----22-3111-113111121221111---1211-1--11------1----1111------------------1-----1---21---11------1-11-121-1----------2-----------------1-1-------2----------------12---1----------------1--3122111--1111-1121-11--1--1111--11-----------------1-1----1---11111111111-------------1--11---------------11111-111-2-11113333132431222------------------------3-11-11---------1-11--------------2---------------------------11--2----5-1 11-123--311231112112334434311111111211-112111111221121-12112121112111111121111111111211111512121111233111-11-24111113111-13111111371-2131211111111111111121111123212131212-1131-11-411122557B1C21121121 * c.134 LmbE-like
[ 597] 11313111111111123111111121121311-----------2-213-1223-32242531111-11 22212---------12122-21--21212221111121112111-1--1-----------22122112221--------11112322311111---1---21--22211--------------1221111111212222233321111111111111111112112111111111111111111111--1-1-111111111111111------111111----------1-------------------------------------------------------------------------------------------1---1----------2------------2--112221----22--211--23-111111111213222223644411111111111-11111111111111112221212223111111222211111111111222-11231121112211111111111111111111111111-111111111111111111122222121131111111111111111221111111111111111111122111---2-1-432223-433122417222212-2112211111111111111111232322221---------------------1----11--211111111122222213332322233-3333322333323333333222211122222222222222222233332231-21111111111111111111111112--1-----1----------11111111111-1111111111111-1111111111111--------------11111111111111112-222211------------------------------------121111-11-2411 -2----1-----21121211232111111111111111111111111111111111111111111-1--1--111------11111---12111211111111111-12-2432211111111111121161-221111111111111111111112111321211211-13322111--------1131-4------- * d.307 Nqo5-like
[ 598] --------1---11------------------------------------------------------ 1111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111211111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111--11111111-111-11-1111111111111111111111111111-11-1111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 22--112-411-111111--11111--1111111111111-111111-11211111111111111111-11111-11-1111111111111111111111122112-11121111-1111-11122-21372-112111121111111--111211211--11111-131--1312232G2222212451311111111 * b.155 L21p-like
[ 599] ----------------1------2---11-111111111111111111111111---1---------- ----111111111111122-21112222221111111111----11111--1121111----11---11--11111111---------111111111--1111111111---------------1---------------111---111112---------------1--------------1-1------12111111111111111111112111111112111111131111111111111111112111111111111111111211212111111111111111111111111111111111111111111111111---1111111112111---------1--111----1------------21--1311111111111111111122311111111111-111111111111111111111111-1111---111111--------------11-------------------------------111111111111111131111111122221211211111111212111111221111121111111111111111111-1-----------------1------1------------------------------1111111111111111121111111111111-1121111-11111111111111111111-11111111111111111111111111111111111211211112111111111111111111111--1111111111111111111111111111111111112111111111121111113111111111111111111111111121111111111111111111-1----------------111111------11---1-1111-------------1111 1111-11-522211221121211111-32123211112111113111112321211311211132111111141511-111211121111221211111121123132922635-253321312236334F2-41413356225-1222132522252423231122122-12221151N1112122-51482111211 * d.117 Thymidylate synthase/dCMP hydroxymethylase
[ 600] 111131-1----------------2----1---11----11----11--21-1-----111--1-1-- -11--11---1---1------------------111-1---1111---------11----11-1111131-1---111---1--1--1111211-11--21-22-312----------------31---111-12-11-------5742331-------1--12332421--1---------1-1--11--11---------------2--------1----21111111111111111111111111222----1--1--1-1111----1--1---111-----------------------------------------1-----------1-1-1--111111----11----1-1-11-1111-11---2-111-1--1-111111--211-11-1111--12-111111-1121-13311232324321443231222251322222222---11--1------------------------------31-1-1111222222211111--211111111122322-1221113113-1121---21-1--111111111----233211-31241111--1222242----12111-11-------2122221221221111331525414522222214534424243244--132-211111145231524444444444-44444444444444444444442211365556566666565564433434421222221222222-122131132222112-31112121---12--122222222112133333333244442354---------23334222223333212222221221111---1--11--11111111--1-------------------------1-----1-----1- --11----1----------111-------------1--------------1-------1-----------------------------------------1---------1---2------------------------------------------------------------111-121121-112--2------- * f.34 Mechanosensitive channel protein MscS (YggB), transmembrane region
[ 601] -----------------1-------------------------------------------------- ----------1----------2----------1----121-1-----------1-----------1--11-----------------------------1-----------------------------------111-------1-----1---------------1-------------------------------------1------------------222111---------------------------------11-----------22-------------------------------------------------------------11------1-------11-----------------------------------1-----1-1--1-1------------------------------1----------------------1---------------------------------------2111362221431--1221-4443211131214--22------2-21-1-1-----2-1111-11---111-1-----1-------------1-------------------------------------11-------1-----1----111----1---------------F7--25B7CD9999787-879E866B8C96A777776A882259FB54ABBCCCD98C6AA82434553--68989A97A898----------1---1--1------1---1----22211-2--1--3333-224-1221-133-------------------11---21-1-11---1111-------------1---------------------------------------------- 1---11--1--1---1--2----211-11-----------2------2--11-3-21111--11111--1-1--113-22111211111173-------1-1--23-13-21-22-55433413376245H1-242124215--4115521254622121323-312-22--211-1----1----A42-1--31--12 * b.21 Virus attachment protein globular domain
[ 602] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------1-------------------------------------------------1--1--------------1-------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------1---1-------------------------------------------1-----------------------------------------1---------------------------------- ----347-----11--------------------------------1-1----------------------------------------------1-----------A11DLMIOKHD9ACDHBZOBKCm*O7RKg9CADSBGGH7FC89H96aCOJFF67A6C968944C3387----2-----------1--2333- * a.256 RUN domain-like
[ 603] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------1----------------------------------1------------1-1----lNWNaRPACE9BGFZUBQKf*H-KIY8H7GKDHHJ9IFBFLC9mEJEAG89P37434274C-168-------1---------------1 * g.32 GLA-domain
[ 604] 22-2222222222222--222222111111112222222222323122222222-1-111-2--1-11 1111111111111111111-1111121111111111322211121-1111111111111111111111111----1-----11111111111-111---111111111111111111111111111121111121111-111111111111111111111111212111111111111111111111---1111111111111111111111111111111111------1111111111111111111111--1----1---1111----111-111111-------11111111111-----------------------11-11111111111111111111-111--1111111111211111-1-11112122211111112231112222222222222222-11111111121121122222222211111112111122211111111111111111111111111---------------111111111121111111111211111111111111211111111211111112111212211111111111111111111111111111111111111111111222221111111111111111111111111111221111111111111111111111111111111-1111111-11111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111242111111222111111111111111111111111111111111111111111111111------------------------------------11-111-1111111 ------1-1---111321211111-1-22111111-111111111121111111121111111111111-11-11111121111-111112122111111111112-13---2----------1---------------------------1-----------1--------11-111-1111-131321111234551 * c.16 Lumazine synthase
[ 605] --------------------1---2-------11----11111--------------111--1----- 111-11111111111--11-12--1111-11111111111-111--------121-----11-12111111----1----1-------3211-111---111-1321-1--------------2--1--1--11-------1-1-111111--------------1211----------------------11111111211111111111111111311111111111111111111111111111111111-1-11-1---11111111121-11111111111111111111111111111111111111--111---1-1111111111111111111111111111111-1111--11--21---111-2---------111211--11111--11--1-111-1111111111--11111111111111111--11111-11-------------11------------------------------------111111111111111111111111111111121-1112111111111111111---1111111111121111111-111-11111-111111111----11-11---------1---------1---1--111111111111111111111111111111--1121-------21111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--11-----11112111111111111111111111121111111123131211111111111----------1111111111211111111111112222--1-----1---------111------11--1-------1--1111-1111------1-1 14--117-411-11311211111111122232321113232221211113211211114222111111-11112111-1111111111121212131211132211-23152764282222342662327H3243922324223513222412432432241442E3313C4332-121B2221223151212143221 * a.294 Tex N-terminal region-like
[ 606] -------------------------------------------------------------------- 1--------------------------------------------------------1------------------------------------------1---13----------------------------------------------------------------------------------------------------------1-----------------1--------------------------------------------------------------------------------------------------------------------------1-1--------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------1--------------------------------------------------2------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------2-- ---------------11111-111---11----111-----1111111111111111111-1-------1----------------------1---1---2-1-------BIIPCD8JCHDAF6dHCUEs*Z1pJNKD8EAF8TDJACCBT5AB8957D58D56JA4S38B126A------1--1----1--------- * b.132 Supernatant protein factor (SPF), C-terminal domain
[ 607] -------------------------------------------------------------------- ----------------------------------------------1---------------------------------------------------------------------------------------------------------1-----------------------------1-------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------1---------------------------1-----------------------------------------------------------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----CA4-----55511312111111111111111111111111111111111411111111111-11----111-----2-111111111111112111111666-E-2GFKEMHLBB79BBBaSAOAm*F7QFN7AA9DABFB8BA99EA8J9DAAA6AC36887C79D48951-------------1111-3533- * e.55 Rap/Ran-GAP
[ 608] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----FDG-1--21111-221111---11111111121----1-111------1-212-1111-1111-----1111--1--11211---1---1-1-----1-1---83r*CAHDDH5AEBEB8FHBN6f*D2MFL6847D5ACDCC798I55P9F58B9EA3DC53A88AFN99-42173151--2521---347641 * g.69 Plant proteinase inhibitors
[ 609] ---------------------1-11111-111---1--1111123-24-2422-1-1-11-------- 1221-----------12----1----------1-------2---2---1-------------1-11------------------11--11----------112-92622-----------------112---21-13322---11113232--------------22241------------4-------111---------------111131---11111--------11------------------------------------------------------------------------------------------41113111111111121221---114--11131114113212111231--3123223-----4125431133114----------1-2252256711--1113424224641-2-1-2-333324---------22211744------------------------------1-312211113445434222266372224143244522--11141422231521122121252-------111223262231521843321787383613776774221111-111111-1-------21-41--32-324111152222221122212311133---2231------11111111111111111-1111111111111111111---111111111111111111111111-11111-111111111111---1---------22512-----------------------1-1344433335434334444-----1---11112233331113333465665541111--723333332222222211--------------------------2-12211111-2-1 -----------------------------------------------------1-------1--------------------------------1----1---1-------------1--------11-141-1--1-111-1--1----1-------------1-------13------1-------------2--1- * c.40 Methylesterase CheB, C-terminal domain
[ 610] 111123321111-1124542553-1111111----1---211131311223212333345--111-32 21121-11111111-1111-11111111-111111111111221112-1---1-1--1--1-111-12122-----------111211--11--11-------1112-----------------11-11-111-12332211131------1--------------11--------------------1---1222222231222212-11111221-112------1--1-1-------------------1-1-----1---------1----221111-1-1---11111111111-------------1-1---111---311------------------2-1-1-23--11--------------2313111122212111112111111111111111111-1111111111111-1111111111112222222232222111111111221131111111111--11--------------------1--11111122222122221121222222222122312112211113232312221321212222222111122-4222132-22421-21-433232111122221------------1-11-11-----22112121121121111111211111121111--12--1------22221221112121-11-21112121221211111121122211221122212222222222111112121121222222222111111-11212222112344112611111232---------1331111222222222312-12212222211221111112-2112222122111----113---------------1-1----------------------------1---------1 11-1----2-----11----1-1----111111111-11111111112---11111--1-----------1-----1-11------1-1121-1121111-111111-212-1111--1-21111111111--111--111-121111--11-2-1-12----1---1-13-22--1-131---12122-112-2212- * b.171 Trm112p-like
[ 611] ------------------------11111-111----------------------------------- 2-2-2--1------14111-11--1212111-4-1-1----12421-2-221--1--1--5-1-5-3-81------------1-----11----------3---5-311--------------------1----11---------2-----1----221-111111-12-121212221212-11-----------------------------------5-1-------13-------------------------------11----------111------------------------------------------------1---------------------------------------------1-1111--------312-----1-1------------12-111-2-1--1---2--331---1-211------------------43-----------------------------------11-1-------22111-1-----1-------1131-----------------1-------------------------1------1-----1-1-----1---2-2-----------------------------11-1----1----------11------------------------2----------------------------------11-------------------------------------------------------------------1---------------------2111--1-----------------------1-----2--------1-------------111111-------------1-------------------------1---------- 1-1152------112443358A358465412226212222232322F599CBEN66A26234-12111-11-2221111-122231----D24128---211232--2AAI4665444322333354366L3-33813434435-361344514442124A56853541-367-41346q3334568AB6Ah3456392 * f.8 Aerolisin/ETX pore-forming domain
[ 612] -------------------------------------------1------------------------ 115-9-1----1--534BB-B855C-BABBB686663113-H4D--------1----1--A8--K-Db1M1----1---111---1--111-11-----12111222-3--------------111-11---111---11---F-221-222-------------422D2-------------11------14111111111111111111132112-1111-122222221122222222222222111121-2--------11----2--11-222111111111211111111111111111111111112211122221--1111111111114122-111-11--111-1111-1-1-11111-----21---------21------12---------------11111-1-11--1224--1---111--211-1-----11--------111----1111-----1--------------------1---------------44333---125554-4--2-----1-11--1--1---21-1---------------11----121---111--------111411----E3-1-------------------------11-----12--11-1111212111122321221-----1------4-1---13114354311-124111223413412412-112224121-11-11111111111--1----2--122222122121-11-111111--11-41---1-11-1111---1---------------113--------212211-111111---3-----1-3----------------11--11--------------1-------------------------1111111111-3-1 --3377--1---111--1-12--382-------233-1-1311---211232-1--12-11-----------------------------6-----------1------1------------------------------------1-1----------1-11-2--212321-----15-1--1--------1----1 * d.358 YdfO-like
[ 613] 1111-1111111111111------1-----------------------------1111111-11--11 1121111111111122111-11111211111121111121-21211---111111111--11311111111----------11-----111211211--111122--211111111211111111111111111111111---2--11-111------------------------------111111-1-211111211111111112211111111221111------2111111111111111111111-1--11--1-111--11-1--------------111---------------------------------12-1---1--------1-11----1-1---111111--1--1-21-11-111-----1------111111111111-111--1-1-1-11111111111111112112222111-111111111111--------111--111------------------------------1131-111-111111111111111111111111111111111111111111-1---2--------2-------111-2111---111----212121211111115-111111111111---------1-111--1221111111111111111111111211111---11-------11111111111111111-11111111111111111112221111111112111111111112111111111111111111111--1111111----111111111111111111112221211---1-111111111-1111111111111111-11111111111111----------------11111111---------1--------------------------11-11-----1111 11--341-742111112132121213111111111121111111111111111111211111111111-11111111111211211-1-12222211112111333-33326342242122242222524J3-343222322324232312212322431184432542365B41315---1-3184551522147561 * c.109 PEP carboxykinase N-terminal domain
[ 614] 1111-111111111111111111111111111111111111111121111111111-11111111-11 1111111111111111111-1111111111111111111111111111111111111111111111111111111111-12111-111---1-------------1----------------------------------------------------------------------------1111111-111111111-11111111111111111111111111111111-111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111121111111-1111-11111111-11111111----11111111111112211112222211111111111-11111211211121112212221122111112111121111111111111-111211111111-1--111111111111111111111111111111111111111111311111111111121111111112111111111111112111111111111111111122111111-111111111111111111111111111111111111111-11111111111111111111111111111111111-11111------11221111111111111-1111111111112111112221111111211111111111111111211111121111111111111111111111-1111111111111111111111111111111111111111121111122111111111111111111111111111111111111111111-----------------11111---------------------1--111-11112-- 111111-152311111111111111-1111111111-2111111111111211211111111111111-11-11111-111111111111211121111111121211112111121-1-1-1111-11551-31111--11111-111-11-1-22112--11221211111211111611111132212212112-1 * a.143 RPB6/omega subunit-like
[ 615] ---1--1111111111-1--1-1111111-11--11231111111111111111-1------11--11 -1--211111111-11111-111111111111111111221213-2111---112121111-2-211242111111111--1111111113111-----1111111111---------------2222122223211111--121211111111111-11-11112111-1-11111-1111--11111--32222222222222222121132222322121--------1--------1------------211--221311-22--1-111--1-222----1--------------1--1--------1---------42-11---121-1-12211-111--2--1-12112131111111214-113-1111111111--------1111111-11111--1-12-11-111111111111111111211-1--11111-1-11111111-111-111--1111111----------------111111111-1111-------21111--2111111--11---111221-111-----1-1111111111111111--11111211111-111111111112111321123112---1111111111--------111---1111211211111111111111211112121--1111---11131111111111111111-111111111211111122211111111111111111111111111211111111111111111111-11-1--111111111----11111--1---11111111---211111-11111---11121--1-1---11111122221211122121211111111----111111--------------------------------------1--1-111-2-1 12----1-1-1-3211221122111111111111111111111111121211211112122222112-11222-222-2212222211-13-212232341-124--112221-1-1111122232-313E1-111-2112-112-123211-2-2-1-13--11--211A--3211--1---112-211133134221 * a.92 Carbamoyl phosphate synthetase, large subunit connection domain
[ 616] 11111111111111111-11111111111111111111111111111111111111111111111111 1111111111111111111-11111111111111111111111111111111111111-111111111111111111111111111111111-1111-111111111-1---------------111111111111111111111-------------------------------------11111---111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111-11111111111111-111-----111--111111111111111111111111111111111-111111111111-1-111-111111111111111111111111111111111-11------------1111111111111-----1111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111-11111111111111111-------------------------111111111111111111111111111111-11-1-11111111111111111111111-11-111111111111111111111111111111111111111111111111111111111111--1111-1111111111-111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111211---1-1111-11111---------------------1111111111---1 11--112-2-1111-1111-11111-11111111111111-11111-12211-1111-11111111111111111121211111112441211111-111-1113311-12211111111111121111892-21111122-11111---1-1-11111-112112-111211112111I1112172131711-----1 * d.59 Ribosomal protein L30p/L7e
[ 617] 111111112221112311F1111212211111111221232321112422843112222121111111 -------1----1--1-11-11111-11111------1-----1---1----1--12----1--1-2222----------1-----------------------1-------------1-------------1-1---------13--1-----11--11------1--1--1----------1-1-1----------11---------1-------------1--------1-------------------1----2-2---21111212-1----------1-------2--------122--122-1----------------1-----1---1----1-----7------122--3--1-----------3-----1----1--111--1----------------11--4-------1112-111-1-1-1--1-1-------111111111----2-1--------1---11---1111-11--------1--------11--------------------------1------1----1--------------------1------1-----4--------------11-1-----111-111111211111111111-1---1-----------------------1------------------1-------------------------2------------11------1---2----1--------------1-1111-1111------------------------------11-----------------------1---1---------------------3--------------------2------------------1--1--------------1-------------------1 1121212-411111213112111223111423323311212111111122121332122111121211121221153223133221111123321311141212151133A432-144121322381422M1-4144243511312213221412221324123-22212212131112951-213woP2*41223123 * d.264 Prim-pol domain
[ 618] -----1---111-----1-----1-----11111-11-11111222111-111--------------- --1-3------1-11------1---1------22222223--11121----2111-11--22--32CA781-1111--1--2111111--12-21-----1--32--1---------------------1111--1--12---312114111-111------1--23351------------1-111---1-------2---------------------1------2--13---------------1-1----2-11---1---1121-1-112--------1-1--11111111111-------------1---------1311-1111121-2---------1-1-11--11111---5-1--------1-13112-----1-212---4333311111111112--11121-1111-1111111112112-111-211212--1--------1----2-1-----------------------------112-2-111121112111----211111111131122321-22211111221121111-----1-------112-23-231-241-1-112-2121223331111332--------------------------22--1121--1-3--------1------1-1------1-------111-1-11111111111-111111111111111111-----1---2-222222222222221111---1--1-------------------------13----------------------1------1111143212222--12---------1---1-----1-1----11211111------11---------------1---------------------------11---2------- ----432-111----1-2-211-3-3111222221122321221----263233---2111------------1---------1----1----1-1---1-2-113-26DM698754443244337583GM51346342254562142215433497362215962-1112-175-66-----61-------4651443 * a.209 ADP-ribosylglycohydrolase
[ 619] -------------------------------------------------------------------- --------11----22256-62336255666133331142-2-3----------------62--6-44161---------------------------------A--------------------------------------5-1--2111-------1-----32261----------------------K----------------1---9----------------D--------------------------------------------------------1-------------------------------------111111111-1-J-33---------1------1----------------1----------1---------------------1-11211111-2--1111--1---11-3--------1---1-------------1--------------------------------------11--344444433433321544413422---1------------1-1--------1--------1--11-1------1----------1--7------78----------------------------------1----------1--------------------------3-5-------3-33--------------------------2-23--------------------------------------------1---2232--2----------------------------41111-3-----1--1-1-------------------------------------------------------------------------------------------------- --11Wl--------15AC3E8CJKQNF221222CE57657566333DDBKA9BB68NHB767----------------------------32A211------2-----C1I1---1-----------1--2-----------13--1------3--1----1141--213522-2----11---4----D---1----2 * b.178 Spiral beta-roll
[ 620] -----1--------------------------------------------11---------------- 1111211111111111111-11111111111111111111111111111111111111111111112111111111111111111212111111111111111111111--------------1221-121211212211111112211111111111111121111111111111111111-----121111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111121111111111111111111111112211111-1--122111111111111--11111112111111111211121111111111111111112-1111111121111111111111111111121121221111111111111121121111111111111111111111111111111111111111111111112122112222221211311111111121111121211112111111111111112211112221121112221111111113311111121111111111111111111111111111111111112121111112111111111111111111111-11111111111111121111-1111111111111111111111111111111111111111111112111111111111111111111111111112222121211111111111111111111111112111111111111111111111111111111121111121211111111111111111111111111-----8----1----1-111111111111111111111111111112111 ----------1---1------2-----111-1122111-1-111-1-1------231-----1-111---1-----1----------21----1---11--1---2-----111111-----1-21-1-15--11-----1--11--------1-1----1-22--12--5-121211------1-327-32----1-1 * f.18 F1F0 ATP synthase subunit A
[ 621] ---1-1-11111111111332112111111111111111111111211111231-------111--11 1141232211111122222-22112222222222222333243422-111111231121122312152231--------12111--12-1212111---112-12-111--------------11232121112211111---212111111112211111-111123212-12211-211122222---12244444234134322422222343133312132222222111111111111111111111---------------------------1--------------------------------1---------112112221111111131111112-1----111121111-12111-1-13114--1--------3222122212311111111111---------121-21112212322111111----------111111111---1121---11111----------1------22222----1-222----1-------1111-----11-1121111--11-1-------11111111-1-------251121-11111111111111111111111222113111---212----1-1-1111--1-1-11-12-1-----11----1-----1-1111111--1421------11111111111121111-111111111112111111111111111111-11111111111111111111111111111111111111222222222111121-1111-----1-1111111111----11-11-1-1-1-1----11-1-11-11121111111111-----1-11-------1-2--------------------------------------1-------11-1---1112 --1---1-21-1--1-1---1-111-----111-------------1-2--1121--11--11---11------11--1----------1--11-2---2--2-----6-3221223322-12153142871-32412214211111--11-11-1111----321-2111--2-1121-1--1221-5-2122----1 * c.113 HemD-like
[ 622] ------------------------11111111------------------------------------ -11-1---11-----11--------1-------222-------12---------------12---13222------------------------------1---1-2------------------------------------1-1111111-1--------1--1111-------------------------------------------------1-----------12---------------------------------11---------------------------------------------------------------------------------------------------------1--1111-------2221111-11-------------22-22121-11-1111111121111-11111-111111111111111111---1------------------------------------22122-111111111-112-1111-1111---------11111111-1111-----1-----------1--1----------------------------2-----------------------------11--111---11------------------------1------1111-111111111111-1111111111111111111111111111111111111111111111111111-111111111111---------------211111--------1---------------11111111111111111----------11111111111111-----------------1-----------------------------------------------------1-1 ----552-----22266655555757644444434444443444435544558734444433111111-1122311111111111111124462221111414233-371C583666444544376453CX5-85A6444745665454365364477436B3674155848553122191112332326321222221 * b.165 MOSC N-terminal domain-like
[ 623] -------------------------------------------------------------------- --------------------------------------------------------------1--------------------------------1--------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--1111----------------------------------------------------------------------------------------------------------------------------------------------------------------8-- --------------------------------------------------------1-----------------------------------------------------A98CDF6AE85NEBUKHLA**a-ZOXGAA8DELKDAJFB7IF6WDE63N35134B72S74666C2------------------------ * d.85 RNA bacteriophage capsid protein
[ 624] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------ ----423-----11233222432232221222222122121411221522222467221221222222-2562224434332222233323132432222322A8A121259BAGG85324545H7495Nk5-EAI25526354726445942C55434222623238346223312217111-2MgS*2*I--1211- * d.88 SRF-like
[ 625] -------111111121---------1121221--1-----------111-111-------------12 1-1--11111111122211-1-1112111111-1111211-1111-2-11111111111----1112-2-1------------111111111-1111--1-1-11111211111111--1111-11111-11111---1111-11-122221--11----11112-2231---------------11---112111112111111121433322112223-11211111141--------------------1----------------------111-------------------------------------111----1312111121111211-33----112--1111222131121121111--111--11--------3--1--11-11--------------2--2-------111--1---1-1-111----------11111111------2-11111111----1111111111111-11---121-222221111111111111111111111522223-1111--11121213-221223232-111111321121111-2122-1-222-111-2211-----1322-112-1111221111111111211-11331221232212222212122221222211--12222------2---11-2222222222-2222222222222222222-1--1212212222222212222212222222-1111111111111---111111111121212---11--11111-1-11111121112233333322222223322-1111111111223333333333312222223332111---111------------1-1--1----------------------1-1111111111-- 12------A44--2-1-2-11--111-1211231111111111211--11----111112211---1-1------11111-1----111321-223-----111----12-----------1------------------------------------1--1121----1-1-21233------32262132-1211-- * d.352 FlaG-like
[ 626] -------------------------------------------------------------------- 1-----1----------11-11----11111-----------------------1--1------------1-111------------------122------------1-----------------------1-----11------1----1-1-----1--------------------1-------1-1--11111-11-1111111-22---1-1-1--1--1111---------------------------11----2--11---1----111--------1-------------------------1------------------------1-------------------------------------111-11111--111-----11-11111111111---1--1-1-1---111-1111111-1--1------------------------------------------11-111111-----1---1-----1----1--------------------1------1-111---------1-----1111111--------1--------------------------------------------------------111112121-11111111111111111111---1111------11111--1111111111-11111111111111111111-11111--1--------------111111111-1--------------------1---1--1-11-1-21111-1--1----------1111111111111111111----------1111111111111111111111111111------------------11---------------------------------------- ----223----1--2--------------------1-111-11---11--------------------------------------1--1----1-----------23329B99D9E98A6A89DM8I9S*C2DCK8986DA9B98A875A77CBB89922433432623C488333222212127747-B33242322 * e.63 E2F-DP heterodimerization region
[ 627] -----1--------------1-----------------------------------------11---- ---------------------------------------1------------------------------------------------------------111112111--------------1-----------111-------1111111111111111111113211111111111111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1111-----111111111111111111111111-1111111111111111111111111111111111111111111111111111-2-111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-------111111---------1--------------11111----------------------------1111-111111111111111111111111111---1111------11111111111111111-111111111111111111111111111111111111111111111111-1111111111111111--1111111111111111---------------111111111111111111111111111111111111111111111111111111111111111111111-------------------------------------------------------1-- 11--111-521122211111111111111122222111221121111132131111111111211111114213121-11211111322384143612111212331143-57465A35723329D473BZ7-7582341A25533463452382344524624122232211241323e2224282231323242334 * d.248 Coproporphyrinogen III oxidase
[ 628] ---------------1---------------------1-1-1-----2--31---------------- --2-11---------------1----------1-----------------------1-----------------------1--11--4---2-1------11-1132-2--------------1--------111------------3---1-----------1---225---------1---------1-1---------1------1-11-1--1---2---------11-------------------------------------------------------------------------------------------1--2222-22--2111112---121-------111--1---1------31------11111--1---------1111-111111----1--1--11---111---1----2----11--------1111111121---------1-111------1----------213-11-1---11-12----111111--113333-11---111-21----1--1---2---1---1--11--121111-112221------1----1111--2---1---1------------12-12112212-12-121--1-22-21--2212-1121111-1-1-2---1----------3--------1-11---------1-1---1-11--11---2----12111212212222122---1112--111111111111---------1111-----221222-21221111---1-22-1---1111----11-12-------------21221------2111--11211111----111512122223121122----------------------------3-21-211111--- 34--HI4-71--335211--2-22-21--11-1234-121-21311-1223122----1--1-12-226142--22112--1--33232--112-1-1--13--13141IE427-E9558436664342BP3-629545681373435559-58133348G556452-23C1259-2-231-1--31-8-58-42-211 * e.61 ImpE-like
[ 629] -------------------------------------------------------------------- ------11111-1-1--11-11---111111-----1111-----------------------1-------1-----------------------------------1---1-1--111----1-------------------------------------------------------------11---1---------------------------111--------------------------1-1-1--------------------------------------------------------------------------1-------------------1-------1---11---11-----------111------------------11-1-1----1-----------11------------11-11--11-11--111111111-111---1--1---------11--111111111111---1-11-----------------------------------------------------------------1-----111111111111111---------1111111--------------------------------1------------------------------1---------------------------------------------------------------------------------------------------1111--------------------------------1--1--------------1--1--11-------------------------------------------------------------------------------1--------- 5511222-511-1433342334344-34434344431434444334344444444444444454555545555455555555554544444533444344413888-491A5876646265766D9564BJ7-677466855775557435428552471-266663955F66454423C4414569773443415212 * g.83 Tim10-like
[ 630] 11111111111111121211111111111111112131111111111111121111211121111111 ----1----------1---------------------11--1-1----------1------------1-------111---------------1-------------------------------------------------1-1--1--------------1--11--------1--1-------1-----11-11---1-----------1-------2--------1---------------------------------------1---------------------2-----------------------------1---1111---1---12---1111---1-------1---------11-11---1-------------------11----------1-----------1--------1------------------1---------------1----------11---------------------1------------1-------------1--3---------------------------------------1-----1-----------1-----------------111---1-------------2--1----1-1-1-1--1-------------1---------------------------------------------------------1------------------------------1---------------11----------------1----1---1-----------1--------1--------------1------------------------------------11--1-------1------------------------1-------1-1-1-1---- 35444332C45333343654443444333344453455654554444335344333333333333333243543435335333343443343333344433634563356A464393344333367373DS3-5452332433323324334335724525846655331953653443X3333367983843334533 * a.183 Nop domain
[ 631] --11--1111111111-111111111111111111111------1-1-11111111-11-1111--11 111111-111111111111-111121111111111111111111111111111111111111111111111-----------1-111111111111---1211121111---------------11111111111111112221111111111111111111111111111111111111111111111-1111111111111121111111111212111111111111111111111111111-11111111-11111-1-111111111111111--------------------------------------------11-----------------------------22--212-1-1211111--111111111111111111111111111111111111-1111111111111-11111111111111111111111111111111111111111-----------------------------11211111111111111111111111111111111111111111111-11111111111211111111111211111-11311211212-212222222221111112111111111111-1-------11111111111211111111111111111211111211--1111------11111111111111111-1111111111111-111111111111111111111111111111111111111111111111111--1111111----11111111211-1111111111111121211111111111111111111-1111111111111111111111111111111111111121-111111------------1-----------------------1-11111211111- ----111-1---1111111121112121111111111111-11111-121111111111321111111-11111111-1111111111112112211111121111-13-21-1115111111121111141112111-11111-1111121-11--111--232--3111111111118121111-131111112231 * d.284 PurS-like
[ 632] ----------------------1----------------------1---------------------- -------------------------------------------------------------------1------------------------1--------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------1------------------1--------------------------------------------------11--------------------------------------------------------------------11111111111-----------------------------------------------------------------------------------------------------------------1---------------------------------------------- 1111775-844222111111111211111111111111111111111211111111121222111111-11111111-1111111111111111-11111-11232-657CBECF9B8888888GH8H8Z*94E8H8887C78F778989C87L9988936I56A75967635A6-324M3233482291664578A85 * a.169 BEACH domain
[ 633] -------------------------------------------------------------------- 1111111111111111111-1111111111111111111111111111111111111111111111111111---1111111111111111--11111-1111111111111111111111111111111111111--11111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111--111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-1111111111111111111111111111111111111111111111-11111111111-111111111-111--1-111111111111111111111111111111-111111111111111111111-11-11111111111111111111-111111111111111111111111-11111111111111111111111111111111111111-1111111111111111111111111111111111111111111-111111-111-11111111-1111111-111111111111 11------1--------------1-1------------------------------------1-111-1-11-11-11111111------11-111111--112---1212-2--1--1--11211-1-352-22431-1--11-1---1--11121--121-2-1-11-1--1-1122-21-223223-21--2111- * d.301 L35p-like
[ 634] -----------1-------------11-----123--------11----------------------- 232--121111111-------1-------------------412----------------21--21-5331------------111-1--1------------------112222122211111---------1-11111---1-2141111111121112111112222111111111111-----1-1----------------1-----1---------------------------11------------------------------------------------------------------------------------1----------3---1-----2--------1-------------1--21---1---1---111--------------------22123-12--111--11---11--11-------1----1--------122--1-1111-111111----11---------1111-11--1----111121-122222211222212--1-11-11--11-11111111-1-11----------------1-1--112-11-2111-111121111--1--111111112222221111111111111122------------1111------------11---------1------3----1---------11-1---1-11-----------2111------------------------1---44444414333---------------------------------------1--1--11111211-2222--1111-1-11-1---------------11111111111111111-11--------------------------------------------------111- 1-2-231-21111-2-111-111----------111----1--1--21111111111-12111-2-21-111111121221---1---1-11112-1--1-111-1-29233237443121323524723N2-334123341221223213335355431211131-212--1412BAH*EDDDCHFJN1FG23-11-1 * d.107 Mog1p/PsbP-like
[ 635] -----------------------11--1---1---1--1111122-11-2422-1-1-11-------- 1221-----------22----1---1--------------2---2---1-------------1-1---------------1----1--------------1-2-52323-----------------111---21-1111----1-111122--------------32221------------2-------211222222221222222111111222111111111111112------------------------------------------------------------------------------------------31123111111111111111---115--11121114213212111221--2124334-----3135631144225----------1-1131133511--1113323223431-211-2-4444251--------22211734--------------------------------211211-12223323111133351112122242312--11131422221421123121242-------11-2232822215318533217A96848146747552-1111-1111---1-------21-4---32-224111142222221122212311133---2241------11111111111111111-1111111111111111111---111111111111111111111111-1111--111111111111---1---------12312-------------------------1444444334434334444-----1---1111233333111332244444333------62112222222222221---------------------------1-11111111-2-1 --------------------------------------------------------------------------------------------------------------------------------------------------------------1-1--2---1--------------------1-----1---- * a.58 Chemotaxis receptor methyltransferase CheR, N-terminal domain
[ 636] ----------------------------------------------------1--------------- -------1----------------------------------------------------------------------------------1-------------1----222222222222222-----------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------1-----------1-----------------------------------1-----2-----11-----------------------11112111-----------------------------------------------------------------------------1----11111---------------------------------1222222222111--------------------1---------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- 3322312-2---3443232222212222222222222222122122221222222222222233333312533236625532223211222223243333321637131168976765575666DB5F6U*E-H7N4563B468556755755C5735757425532243733423332E223339BBR2M93244443 * a.42 SWIB/MDM2 domain
[ 637] 111-11-----------------1--------1-11111111111-1131111111-1111---1--- 222-1---------1--11-11--1112122-1---1---1-1-----------------11-111---------------1--1221--------1-------1----11111111111111111111111111112--22111--1111------------111111---1----------------2111222221121212112211111111111-111------1-11111111111111111111------------------------------------------------------------------------1--1111111-1---11----1-1--1-121--22211-11--1---1-21111-111111122222222222------------22222221212-2122121222--22111--21111-21------------2112----------111111111111111------13-111111111111-11111121111111111111112111211111232-2112211112111111122222211-11221122222133323232222221122--------------------1-111232221111121322222122222222222221--2121------22222212331222222-3322322222322222222222221112222222222222222222222222-222221222222--211211123221121122222221111222211111111-12212221221311111111---------122222222222322111-1--11111111121111111----------------------------------------------111- 1---11--211-11--1111111111--------------------11121111111-1111----------1--------------1----1---------------2121-1--2111111-1111-1C1-1121111111111-1-12112-1121---12---11111111-11171-1123234-41------- * d.206 YggU-like
[ 638] 11-1---1-------12---1--13--3-234------------1-1-1-222-111---1-2----- 273-1---------------------------2---------1--3------1-1------1-11--111------11----------YVaO-G23---7D3D4Z1M3S----------------1---11--1124469---2-------------------3-1---1------------1---2-----1-------1------------------------------1-11121121111111-----2---11----------1--5------11111-1---1111111111111--1111111-1-11----------------------------112----------1----31---------4----1--------------------------------------1-----------------------1-----1----------------------------------------------------1744-1--1---111111--1111-2-2--1----33-1--1------1-------------------2-1----------------2----1-1332243---------------------------1113-1-13---2-------1----1-M1-----------------2--2-11IH111211--7111111111I1D11-11B1114X--2-1--------------1--E-------11111111111--------------11-1---------------------1---------11----111---1----------144111111---351--1-1-111------1-------------------------------------------------1-1--3-3 -----1-----2--1----------------------111------21------------1-------------------------1--1D2-121-------122---144555441322133342324D2-32311223224311211411432142114-3-1-5-----2-----1----11----11---1--- * b.24 Hyaluronate lyase-like, C-terminal domain
[ 639] 1111311111111111111111121--111-111111-1111111-122-22212222222-111111 1121-----------1111-11--1111111111111-111111---1------------111-1111111----------112122211-1----------111-121---------------32122312223---11111-12222111--1111122111-1222211211112111111111231-11---------------111111---111-1---------1------------------------1------------------------1----------------------------------------2--11---------12-22-111--2-----12112-22223122221---12---1-----11122--133333------------121111111---111111111111-11-11-1----111---------11------------------1---------------1-1--------1111111----11111111-1111------------------1---11222---------1--1-1-212-222122112-21221222211213242----------------------22111---1111111-1-----1-----11-1-11---2111-------1111-11111111111-111111111112111111111111--11111111111111111111111111----------------111111222221111------------------------1111111-1111----1111---------1----1111121111----------------22------------------------------------------221222222222-- ------1----121111111121111111-111111-1--11111-11111-11113-1211121----1--111------33312111-2111111111111111-12-63533352323-3254372FW3374922244332313433411936463---132114222--2--333N242322232112211112- * d.273 YjbQ-like
[ 640] ------1---------------------1---------------1----------------------- 1-3-1----------------------------------------------------------1---2---------------1------1-----1---1---111--------------------------1-----------53-1321----------11---121-1---------1-----------------2-------1--------11------------1----------------1---------------------------111-----------------------11----------------------1-11111-1------------1------------------1--1-----2--------------------------------1-------11--------1-11-----------------11-------------1-----------------1-----------2--1--------1------1-------------1-----1---11---1--1---1----1------------1-1----1--1----------------111---15---------1---1----------------------1---------1-------1----3--------------------------------------------------1------------------1-1-------------111111-1111-------------------------------------------111111----------------------------1--1221----2-1-----------------11---1--1-1---------------1-------------11---------- -1--421-1-11--2131-133-4-31---2211------------5212233211114131--12111-1-------11-----1-1-1--32-14-1-1--131--L6mK7F6C75574679HB7B7DxA-97E4A69E64CA37976662G55479BD977512--1--1D6-16163--13CEJM-AL1-3658- * a.119 Lipoxigenase
[ 641] -------------------------------------------------------------------- 1121111111111111111-11111111111111111112111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11122111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111222121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111---11-11-11111111111111111 ----112-----1111------------------1-----------1--------------1--------1--------------------------------112-12-2-----1--------------------------------------------------2-----1--12272212-4255-221-1111- * d.99 Ribosomal protein L9 C-domain
[ 642] -------------------------------------------------------------------- ---------------------------------------------------1----------------1---111----1111-1-------------------------111-11--------------------------------------------------------------------------32344444564554455433333345632212111111115211111111111111121-311111111211-112211111---12111122222111111111111122222222222222113311112333222222222222443332222251131-1333444234233333--1--------1111111111111111111111111111-11111111111-111111111211111111111111111111111111111111111111--------------------11111111-1111121111111111111111111111111211--111111111112111112111111111111111111-------------------------------1-------------------------22111111111111111111111111111111--11111------33223333333323332-33433333333333333323432222233323333333232233133311221222222222222--11111111111111111111-11111-11-12222222111111111111111111111111111111111113222223322211111111111111111-------111-1---11---------------------------------------- ------------1------------------------------------------------------------------------------------------------1---1-1-1111--133-21171-52---111-1311----1-1211--1------1--------1-------------------1---- * b.105 Penicillin-binding protein associated domain
[ 643] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3323--2-511-------------------111-----------------------1------------1--------------------------111--------283gEHDEGMC77FCFDOLAH9Z*C1OCTAB9AFBDHD9CABAB97ZAGB9B14778964E79J3662-21141-113254B-412545141 * d.314 PUG domain-like
[ 644] ------------------1--------------1---------------------------------- -11-111111111111111-11--1111111111111-111---111-1------11---111111111112111111-11111-11111111111---1111111111--------------111-11----111111111111111111-----------1-----11------------1111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111112111111111111211---------------------------------------------------------------1111111111--------------------------------------------------------1111111111111111111111111111--111-112111111-111----111111111---11111111111111111112111111111111111----------------------11---1-1111111112111111111111111111--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1-----111111111111111111111111111111111111111111111111111111111111111111111111111111111111111------1-----------------1-------------------------11111111111111 1111111-62311121111121111-211111111112111111111111112111111111111111-1111111121112222111111111131111111111-21-4232Q222222122852322I3-222232221232121222222222231112321-121111341211711111111211111211-- * c.110 DTD-like
[ 645] 11---1----------21222321111121211111111111111111111111---11111--1--- --1------------------1---1---------------1-1-1---------1--------1-----------------11-11111111111---111112121211111111211111111112111111222--1111-22222212222111111221122231111111111111112311-1------------------111------------------1----------------------------------------------------1---------------------------------------1--11111111111--11-----1---1--111111111111111-1--1121111-----111111111111111111111111-111111111111111111111211111111111111111---------1---1211111111111---------------1111-1-211111112222221111122321111112113132-1111111111211111111111111111111111111-1-1-111111112111111111111111111111111111111111111111111111112-1-111111112111111111111111--11111------11--1111111111111-1111111111111111111111-121111111111111111111111111111111111111111---11111111111-111111111111111111222221211-2-21221112111111111---------11121111111111111111111112111111-111111--------111-------------------------1111111111-1-1 ------1--1-1---21423332342322-11122212121312222222333333223111432111121142411-21133335---4821132211115222----131-11-------1-------1----3-----------------1--1----1----11-----1-22214---124238331-12-1-- * c.106 SurE-like
[ 646] ----------------------------------1----------------12--------------- -------------------------------------------------------------------------------111-------------------------1-------------------------------------1121111-21111111111111111111111111111------------------------------------11---------------------------------------------------------1----------------------------------1----------1-2-------------11----------------1-1----1------------------------------------------------------------1-----1--1----------1-------------------------------------------------1-------------1----------------1--------------------------------------------1-1--11-1-111---------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------1-------------------111111---------------------1---------------------------- ----223-423-3322221244323213322222223212222333222222343132433332222222221222222222222122215222211222221335-32169A99BD8584574J9596VyB4D9A674C8876A47865963G5997738A6344363432122234482225666BF2C9111334- * d.18 ssDNA-binding transcriptional regulator domain
[ 647] -----1-------------------------------------------------------------- 111111111111112-111-1111211111122222111111121111111111111111211121121121111111111111---1--------1-------11-211111111111----2-1-1-11-12111111---111111111-1221111111111111111111111111111111---111222221121222112112211121121121122222211122222212222222222111111111111211111111211111122221111111111111111111221112211212111111111111121111111111-2112111-1111112111111111111--11-----1111-1----111111111211111121111111-11111111--1-1--11111111111111-111-11-1111111111---11111----1111-1----11--------------111111222-111111-1111---1111111-1----------11222212222----111-11111111111-11-11111-1-11111-1-111---111111111-2---11111------11---1-1-11---11111-1-1------1----1111---------1-1-----1--1----1-----1--1---------1-----------111111-111111111-1-11----11-------------------1111111111-11-111111-1----11111111111111-1------111-------1-11111111----211111--1---1-1-11----1111111--1111-1111-1-111---11---1-1-----11--1-1111--11111111-3- 1-1---1-31------1312---------21--11---------111-1---1-111-------1-22---11-2------1-----11---11--212--1--1---3121-2-1------12542718N2-51C122121231-2-3-4--1--1-2113-2-----1122211332L322-1221511321----1 * a.172 Helical scaffold and wing domains of SecA
[ 648] ---1--11111111-1-1111111111111111111111111111111-1111---------11--11 111--1-------------------------------------------------------------------------1111111-2------------1-22111-1---------------------------22-1------------------------------------------1--11---11133333323233322311112133311111--1-111-11-11111111111111-1111-------------11---------------------------------------------1---------11-----------1--1111---------1111111111-11111-1--1-1-1111-----111111121111111111111111-11111111111-12221121112212-1122-----2--1111111121111-2-------------------------------11--111112-----------------------------------------------1111111121111111----11111111111111111111111-11-1111--1-----------------1--11--3211-11-11211111111111111111111--1121---11112111111111111111-1111111111111111111222222221111111111111111211111111-22112222222211-1---------111--11-1-1---------11111111111111111111111111111---------111121111111111--111111111111112-111111---------------------------------------1---------- --------------232212222222322311232222122322112122222212222222223222222212222222233322222242222322222-23321-12-242-4421-3222C31A3IW6-44641225236223211331443332---1--11------------1-------1-32-------- * e.37 Siroheme synthase middle domains-like
[ 649] 11------------------------------------------------------------------ ------------------------------------1212-1211-----------------1----542----------------------------------2---2------------------------------------12--11-----------4-----11--------------1--------------1-2--------1131------1--------------------------------------------------------------------------------------------------------2------------3------------------121---------------------------------------------------------------------------1---3-----------------------2-------------------------------------------------------------2-----------------3-----------------------12--------------------------------2-------------------------------------3--1-------------------1----------4------24----4---2---------2---------33----2---------------------------33333333333---------------------------------------2343----------------112----------------------------------------1--------------------------------------------------------- 87662---7-----2225433333333222222222332323322222322232-13434332112321111211122222111111111212111222111-21---51iEBADCF7675677BA4B3Jf8-G9P8678D68847787484897C887HB5-11--------1---114111A13113421-2-2--2 * d.209 LCCL domain
[ 650] ---------------------------------------------------1---------------- 1111111122111111111-111111111111111111211---11111111111111111111111111111111112122121111111111111--11111111211111111111111111111121111311111---1111111111111111111111311111111111111111111111111122222222222222211221122221111111111112111111111111111111111211111111111111111111111111111212111111111111111111111111111111111111111111111111111111111111111112111111111111111111111112111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111-----11111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111211111213111111111111111111111111111111111111111111111111111111111111111111111111-1112111-1111-111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111--------------------------11111111111211 --------------------11-1-11-------------------------------------------------------------2-1---------------------------------------11-----------2------------1-2--------31----11---1------2--2--2--1-1-- * d.146 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
[ 651] -------------------------------------------1------------------------ 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112211111111111111111111111111111111111111111111111111221122221-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 ------------------------1----------------------1-----------1-1----1-----1-1-----------------------1--1-------------1-------------------------------------2---1--------111-----11---2------------------- * d.202 Transcription factor NusA, N-terminal domain
[ 652] --------1111-1---------------------------------------------1-------- ----2--------------------1-----------------------------------------1--------------------------11----11----1-1-------------------------1---1------------2----------------1-----------------------------1------11---------1--------------------------------------------------------------------1------------------------------------1--1-------------------------------2--------------------------1--1------------------------------------1-------------1---------11111111---------------------------------------------------------------------------------------1----11-------------------------------------------------1--------------1---------1--------1--1------------------------------------------1---1--------1--------------------------------------------------------------------------------------------------------------------------1---------------------------1-1--1---------1----------------------------1--------------------------- 1--11-----11---1361143242322322331121111111-112112234211333212112112111212121-11111111111A133-211------1-1--748A543D65436453CA553CS7-65A344364564352246526543F834239-8-21--4R21-75-----116TCJ2*J--ZNka2 * b.77 beta-Prism I
[ 653] 111-111------1-------1--34433333-----------------1---1--211131--1--- 112-------1--11----------1----------1121-2--1-----------------2-1-1---1-------1-1-11----121-----1--------2-1-------------------------1-2111111231-----------------1----12-------------33322--112122222333234233432111123311132222222228521111111111111111111--1-11-1---11--1121112----11111-11--11111111111-------------1111111111121-2111112121121--122221-11111--4314--2122-1-1--1-1--11-11111--322111-221-1111111-111-2212212-13-112211111312211---1---1--112222222221111-----------------------------1-11---1--2222-212231-----11-1----11211323------2121121113232111111---------11111-1-1-111-12111-121221512-1--2-1--------------------------------121-----1----11----1-1--11---21-1-------------111111111--111111111111111111-1-1-1111-1--1-1-1--21---3--1---------------------1-1-1-1111111-----------------121121--2-111111-112121112112-------------------21--111111111111111--11221111111111111-1-------------------------1-111-3----11- ----32--411-23-21-2211-2112221----112-1--11212----3314-13-----1-1-1---213---4-12-242122--3261221-1---2---2---242312241511122241236F4124422123111312--1311213331111-11----1---2----------112-2-1-1--1-22 * e.60 Thermophilic metalloprotease-like
[ 654] -------------------------------------------------------------------- 1111111111111111111-11111111111111111111111311111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111117111111111111111111111111111111111111311--1111111-11111111111111111111111-111111111111111111111111111111111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111222222111111111111111111111111111111111111111111111111111111111111-11111------11111111111111111-11-11111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111--11111111111111-1111--111-111111111111111111111111111111111 --1-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-31-1---224-3----111- * d.48 Anti-LPS factor/recA domain
[ 655] -------------------------------------------------------------------- 1111111211111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112211111211111111111111111111111111111111111112111112111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111-111111 -----------------------------------------------------------------------------------1-1----------------------2--------------------------2--------------------------------------11--------------1-2111--1 * b.111 Small protein B (SmpB)
[ 656] ------1------------------------------------------------------------- 611221-2111--11------3--2-------21-2-1-1-111--12-2--3---11----63---11-1-111111-1-111----1111--11----1---2--111111111111------11--1--1------------A312-----------1-1-11-13-1--1--1-11--11111------------------------------11--1-----------111111-1111111-11----1-11------------------------------------------------------1--------------1111111-1--1111111-1111-111----1--11--------1-11112-1----21-12--11111-11111111111-13123122--1-11111111111111111-112-11-1-3333333351121-11----1-----1-------------------43221-1111212211411112211211112-4----1-----11-11312-11--12312-31111111111-11-12-1-1----111---1---2--2--11--1--1------------1----1--1-11-4--111311--1374--2--23-5122------1-1-------121243-111-2-311-21-2232--123111-21-3--24212---21--21-12222113-231-11-2---3---1-32---1-----212--1--111111-1----112-1121113111-1--1----31-------1-11111111-2--1-1-11221222111111----111111----------1--1----4-------1-------11--1---------------4-- 1111--1-1-O1----12-1---------1-11-------1----1-11-----11-1-----1--1---1-1--12-1----------21-12121---11---2-141641171321213-353142CP7-724222211242321124-1333-33---1411--1--111--121G222-1275213-22-12-1 * d.89 Origin of replication-binding domain, RBD-like
[ 657] -----------------------1---------------------------11-----122------- 1111111111111211111-11111111111111111111111111111111111111111111111111111111111111111111111111111--111111111121111111111111111111111111111111111112312211111111111111111111111111111111111111121111111111111111111111211111111111111111111111111111111111111111111111111111111111131111111111111111111111111111111111111112111111111111111111111111111111111111122111211111111111111111111111111111111111111111111111111-11111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111--11111111-111111111111111111111111111111111111111111111111111111111111111111111111211111111111--11111------11111111111111111-1111111111111-11111111111111111111111111111111121111-111111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111111121112111111111111--11111111---1-111111---11-111111-111121-11111----------1111 ----------------1------------------1--------------------------------------------------------1------------------1-1-1-------1------------------------------1--------1-------1-1-----------1113-2-11----- * e.49 Recombination protein RecR
[ 658] -----------------------1----1-1--1-111-----111-11----1-------------- 11-23222222-1111111-11--1111111111112154-2211231-2224532-2--124231323311---111---1-1111---11-11111111112111111------1111111111-1-111121------------2----21---1-----1--1----111---1-1---------11111131311112133111112211312211211222321211222222222222222222212111112121222211111--111-111----111111211111111111111111111111111111111-22222221231312112111-21111111-11----122221211-111----1-------------------------1------1------1---11-----------1----1----------------11-----------------1111111111111-------1-122122111211111111112222212111--1--------1-1-----1--------1-111111------11--1--11111111---1---11----22221211211111111111111111111--111-1-----211111-1111111111111---------11-121111212222232322-222232222222222222132411111433432433344444421111111-1111111111111---------------31-111111-111--111-1111-2111111111111212111-121-----1---211111111111212--11111111-------1--------------1---------------------------11---11111-111 ----33-122--12-11-11-1----1111111---2111111-------1311221-----1--------------------1------1-1--------1-----2-2------1-------11----1---13----21-11-----1-------1---222--1----1-211--8---11-----21------- * c.141 Glycerate kinase I
[ 659] -----1---111--1--------------1-1--1----------1----2-----1--1-------- --2----1112----------1111------11----1-------2--1-----1--------1---2--1---------2-1-------2--11----1---12-2-1-----------------------1---11-1---1---2-----1----------1---1---------1--------111-------------------111-----1------------2---------------------11------------------1------1--11-------------------------------112--------1---1------1------------------1---1-------------1-----------2-1-11----------------------1--111--11-1--1-------------1-------------------------------------1--------1-11---1-1------1121------2211------1----11-------3--11---12-----2---3-11----1---1-2-1---1-111------1--1--1--32-1---------------1-----------122-----1----111---------11-11---1-1-------11--11-1111111111-11111111111111111132221-11-44433444434333341---1112--111111111111--1------11111-1-1222121---1-1-1-11111-----1---------11-112--1111-11111-21132222211223-13-1--112----------11-----------------------------------11---11-1-----1-- ---2-33-3411113114221111-1---12222331--1--1-343-366636313112--211121--11-42132221332222314141544--32-721---126B5733332142334E81326P4172A31535323354312524A1433445224A2123336-4535--4412-1B31465-3273321 * e.70 MalF N-terminal region-like
[ 660] -----1---111------11-11-1---111111-11----------------1-------11-1--- 2111----111--142211-13--142222217454-442----1-1--121---------1-11------------1--1--111--11-1-111-11----1------------------------1-----------22-1-1-----------1-111---1---1-1-----1----11-1---1111--2-221211-211-1-11-121--1---121111112-199B699B9B9999B111111---11-11-122--111211111-1---1111-11111111111111-11-11111111-111111111-1-----------1---111---1-----1---22--2-------1----113---------11111111---1---1-----111---1--111-------------------1-11-----1-1--------1---1---11-------1-----------------------1-----1111111-111111--1111-111-2221--1111--11111111--2-----1-------11------11---1---11------------1---11-111----------11111111---1111111-1--1--1112211-111--1---11-1-----111---11-----1111111111-111111111111111111-111-----11-1-1111111111--11--------------------1-11-11---1---311-----------1----------111--11112121122221-11-11-1-111-11111111--1111--------------1121--11-1------------------------------------------1---112- ----111-211---11-11112113121111111111111111222112-122211311---1-11-211---3-1-11-1-----123212-1-2--11121123-22132533321221-213133-6D5-535211411221123-2321331225---231112---212-1211J123--1-13221-11-1-2 * f.6 Leukocidin-like
[ 661] -----------------------1-------------------------------------------- 111111111111111-111-1111111111111111111111111111111111111111111111111111-11111111-1--111111111111--1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111112221111111111111111111-222222221111111111112111111111111122111111111111111111111111111----1111111111111-----111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--11111-111111111111111-111111-11111111111111111111111111111111111111111111111111111111111111111--11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-------------------------111111111111-1 -----------------1--1-----------------------------------111112--------------------------------1-----------1-2---------------------1--------------------------------1-----------1---6-----1113-21111---- * d.315 TRCF domain-like
[ 662] 111-12-121112224431111114----11-21121-11--1321221-11-21-111-----2-3- 221-------------111-1-----111-1-------1---------1-------------1-----1---------1215-2111------1-------------1-----------------11-----1-------111-11-2-11-----------2----1-1---------------------22-------------1---------1---1-1------------------------1------------1---------------------------------------------------------------121111111--1-2-22--1--21-1111-1111122121--19----12-------11--1-----11--------------1-------211--------------111-----1111----11111111------1-------------------------1----------1----1111111111111112221-11211-1---1-1-----11-----31----112111111---2-1-1233122142323-13223-22-2332--33-----------------------------2-1-1---111222-112111-1121-1-------------21111111111111111-111111211111111111112211111111113111111111311111111--111111111111------------------311112111111--1-----1----1-11111-1--11112-1------------11------21-1-11------------------------------1---------------------------N--1121------- 21---111931-12-1------21--1--1---1-11---1111--11----1--1---1-1-------121--4-1---1------1-11---3-111----------2846737211--122A4-5-JX71B5622-143333221-21--52435-6496DA-442451233-3--d---212-23-21-149-32 * e.59 FdhE-like
[ 663] ----------------------------------1--------1------------------------ 1-----------------------1------1-----121----1--------1-------------1---1----------------11-------------------------------------------------------------------1--------11-1------------------------------------------------------3--------------------------------------------------------------------------------------------------1---1111111-1------111------1-----------1------------------------------------------------------2---11--------1-1--------------------------1----------------------------------11--111-1---------------------------------------1-1------------------------1--1-------1---------------1------------------------------------------------1-------------------------------------------------------------111------------------------------------------------1-1----------------------------------------------------------------------------11--1--------------------------------------------------1------1------------- 11-1-33-A5341152111234334112321222221-1--1122134423267211213524-5-11-24111-24342232-2--1-35215-2-1-122-1-1-2M1jHB7ABC2464458G72E5Mm8-C6N3353B49E746732A64C49698--133532321546F42166M2327-36321513323125 * e.76 Viral glycoprotein ectodomain-like
[ 664] -------------------------------------------------------------------- --1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 221-112-511---1--------1--------------------------1-11--1----------------------------------------------1---33-79E9DCDBA67ACCMLAJCf*O3LCV9ABBG9CF89AA88G88W8E9A628744425C44L9E321212C111222776-931-----1 * a.226 Her-1
[ 665] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111111-111---111---------------------------------------------------------------------------------------------------------------11-----------------------------------------------------------------------------------------------1---1--1-------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111------------------------------------------------------------------------------------- 11--771-1-1---1-111111111111111111111111111111-111111111-11111-11111-11111111-111----122212111211111-11414-6-1BCFAEAD98789A7NG5B8S*G5GEF79A7B4AC978788B98JAC9A967E55763343A2364------112-154C1C3127E9F2 * d.324 DUSP-like
[ 666] -------------------------------------------------------------------- ----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------1---------1--------------------------------------------------------------------------------------255556e-6248H4**8P3**e-TGM-A46ZABJC6C836a9-8ABB4A31--9----------------------------------- * d.288 GTF2I-like repeat
[ 667] 114334----------474553342-----34--111111111-11111-313-5565557-326--- 1---1-------1-21311-1---1-111111-222--2--3--311--1211---------1-1-1112-----1---122---------1--------------1------------------1---------21121---112--------------1121-------1-----1----1-143---1--------1-1--------11-1------1-------------------------------------------------------------111-------------------------------------1321-1111111-1--------------4--2211-2B2-54311-14---31-1--1-11---1------1------1------1--11---1--11-------1-22--11-----1---------------11--12-------------------------------------1312-2221212211133212211112-1141---21-21-1111-11---1----------------211-7B41492163222-596143553--2-2-64---------------------2-----------------111-1-1---11-1-11-----1--------1-1----1222122212-211122-11221111111--------1-----------------11-2122------------------------1-----2------1------------11-1--1-1-------1-1-1---11------------------------111-1---------1-----22---------------------------------------21---2------- --1--1--41-----244131121122111---111-111111---1221134413441111-----1-2--------11122--1-3-33141-1-----3-1-3-13142-84466-18415-2-329D11545221-51132111-3132-3621--11-2-53-121-11-1-1-C---11244327-21-11-- * a.110 Aldehyde ferredoxin oxidoreductase, C-terminal domains
[ 668] -------------------------------------------------------------------- -------------------------------1---------1-21----------------------232---------------------1-11----11233-4--------------------------1---22-------53353322233---12123153353------------1-1--------------------1--------------1---------2---------------------------------------------------------11111211-----------------------------------------------1--------------1---------------21221-----213122111122133443444444-22323522353-333333333343234122444543433--------11112-44--------------------------------1--1111---------------1------1-1---------2-11112-11---1------1111--11-133-11221-1----------1-----1--1-2411-111111111111111111111-----223342122222222222222222313212--13111------23112222782222321-4222223222622222222333221122222222222222222222222221-222222222322--1211111111212233111222121123112----------3223323233333223433---------122243333333333----------------2-111111-------------------------------------------------- --------211-1-11112111111111111111-11111-11-1---111111111-1111111111111-1-111-11111111-1--1111211121111--1--1-2-1--1--11--2----2------12--1-1-1--------------2---------------------4-----1---1-1------1 * a.287 TerB-like
[ 669] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------9-------1--------------------------------------------------------------------------------------------13-jPQGEIC8768CCAMP6J7b*G-OHa9887H9BC54A976I78VBHCCDAPA26N9-54312272---111-2---------------- * g.64 Somatomedin B domain
[ 670] -------------------------------------------1-11--------------------- --1-1---------12211-1-111111111-11112-1----11-----------------1-1--111------------------11----------1-1-----------------------------------1-----1111211111111--11-111-1112111-11111----------122222222222222222222222222222221221111113121111111111111111111-1-2112-121----11-1---------1-------11111111111----------------------1122222222233222122212222121-22211222222-1122222111------------12322---31111------------33242122----1--113---12232---------------------1--111---------------------------------1---3111223444221111221411111142211111111122111111132121121121---------2111-----------------------------------------------------1-----211--1---1-11111---1111-1--1----1-11-------34125335556556654-554555655556455566434322111554555555543535562323334--422222222222---1----------------------1-1-211--11--1--111222211112-1112---111-111111212-2222232-22111-------------1-11--------------1--------------------------------------- 11------1--------------11-------1-----1--------1-11-1-1-2---------------------------------------------11----1---------------1-----------------------------------1--------------121-----222112-----2---- * d.125 Ornithine decarboxylase C-terminal domain
[ 671] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------1----1-111--------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----222-4222123224-222222222322122212-32122222222222332222322222222242222222222222222222222322232222-12--212-37GA888K87A7977CB7B9E*8-C9G58A7AAAB748947D94R9888A5BE85AB25265486223-2A213---------222222- * d.223 Polo-box domain
[ 672] -----------------------------1--------------------111--------------- -----1--111-------------------------1------------------------------111------------------------------1---------------------------------------------1--11-----------------------------------------1---------------1--------------1--------------------------------------1---------------1-1----11111111111111----------------------------1111111-1-----------------------------------------------------------------------------------------------------------------------------1-----------1------------------------1----------------------------------------------------------------------------------------------1-----------------------------------------1----------1-------------------------------1------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------1---------------------- 11--111-41--333331-1132414------------------------1213--1-2-1--22----3--1-2------22222------3----11216222311D138DBDC96575775JC787FfA2E7B3654666A547644655C756671114433433452221-551A11133ESbq1fF22A9B93 * d.23 Tubby C-terminal domain-like
[ 673] -------------------------------------------------1111--------------- ----111111111111111-111111111111111111111111111-1---1111-1--111111112111111111--11-111111111-1------1---21111---------------11111111111111111111-21111111111111111111121111111111111111111111-11211111111-11111111222211111111--------21-----------------------------------------------------1--11111111111-------------111---111-----------------1--1-----------11111111--11111--21-11111111211111111111111111111111111-11111111111----1--111-111111211111111111111111111111111-----------------------------121111111111222211111111111111111111111--11111111121111111111111--11111211111-2111111-11111-11111111111111111-11----------------------22111211-12211222222122222111211---1111------11111112222222222-2222222222222222222111111111111111111111111122221221-111111111111---------111111211111111-11111321111111111-11111111111111111111--------111111111111111111---111-------11----11--------1----------------------------11--1-111-1-- --12---------1132212222222232222221121313222222222221222222222111111-12311123122111111111111222-1112111311--2---------------------21----------1--------1----1-1--------1----1---211711211---12----1--1- * d.276 Hypothetical protein yfbM
[ 674] ---------------------------------------------------1---------------- 11111---------------------------------11---------1-----------------1111-------1111211111222212221--1111112211---------------22222222222-----11121111111111111111111111111111111111111111111112111111111111111111221111111111111111121111111111111111111111111-1-11-----11--111111111111111-111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111-----111111111111111111111111-11111111111111112111111111-11111111112132333333111211-1------------2211122-22221-----1111111111111111211111111111111111111111111111111111111111111111111111111111111111111111211211111111111122111112111111111111111111111111111211111111111111111111112111-111111--11112121111111111111-1111111111111111111111111112112122222122221111111111-1111211111211-11111111111111111112111111111112222111112111111111111211111111111211111111111112111111121221111111-111111112111111111-1-------------------------11111111111111 ------------------------1-1--11--1-----------------------1-------------------------1--------------------------------------1-1--------------------1------------------1-1---2----1------------2---------1 * e.53 QueA-like
[ 675] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------- ----423-1---222221222222121221222222221222221-221132222222-21121222222222222212222322333311121122222231334-6--79HGAAH88667A9UM7F8L*E-CDE7CA8E49FB5C685935F8A99A33235A4197417D65-111------122-25----1--- * b.95 Ganglioside M2 (gm2) activator
[ 676] -----------------------------------------------1-------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------1-1--------------------1---------25--1111131221-1---1--111111-1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ --22--7-----22-152121122-2111-----1--1-1111-----21A343-11-11-1------------------------------5---------------3-i79895444646758B475cuC-D8854516237433244645C3A7471-1VOCE2N79CPU6---1-2--2--2RHi-EB--11B52 * g.10 Hairpin loop containing domain-like
[ 677] ------------------1-------------------------------422--------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------1-----------------1-------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------1--------1---------------------------------------------------------------------------------------------------------1------------------------------------------------------------------- 2211433-421-22322223222222222222222322221222222222222212222222111111112111112111111121222232222222232223241324668676D6644787GE5C5P*A1B7L7456C57A638685964B5A67626K5335452G635341121J1-111A3872931434342 * d.105 Subdomain of clathrin and coatomer appendage domain
[ 678] ------------------------33311111------------2--1-------------------- 21-111111111-111112-1111111111111111123111112222132-222111--111-1221111-1111----111-----2-1---------1--2211----------------1---11---111111-----1-1--1---11--111111---1111-111111111111-----11-------------------1-11-3---111-2--------12---------------------1------111-----------1-----------------------------------------------1-11-----------1-------1---1--1--11---1111----1---1-11--2-----13335211115111111111-114-42225521451-122166343423231212112211112111111113311-111------------------------------1312--3-122131121----2221-2-1112332113-151--1---312311--1---21------11-213-312-1-----1-------11-1-1211-1112----------------------1---1----1311----2----1-1----3-11--1---111--------1---2-1111111111-111121111-111-11---231--11-1---1111--1-1--1-111---11----------------------211---11-------------11-3223211---2-11212524232333124------------------------2111111----111--1-11--------------1-----------------------------------1--1 1-----1-1---2111111111112111121-111111122111211211-21111111111-12111-11121111-11111111---2211111---1-111---14153121113211432212315F3-214112121111-122132291211121-1121-1211--111211-1111112211311111111 * d.303 BB1717-like
[ 679] ------------------------1------------------------------------------- 1-1111111111--11122-21111122222111111111111211111--1---11111111111111111111-------------------------121------11111111111111-1--------------------------------------------------------------11-11122222132112411211111121122211--------121--------------------------------------------------------------------------------------------11-------1-11111-111-1---1--1-11111---1---2-1-----111-----1-12221222112111111111111-11111211111-111111111111-121111-111113211111111111111-1--11111111-------------------11111-2---112222131111222111-1113222331-1222221222223113231--11-11111111-1-23-2131-1-------------11-1221221-----------------------------23-112121122222222122222211222---1--111----11-21211111111121-1111111111111111111122--1111111111111111111111111111-111111111111---1----------241-222221211112111----------11--1-111111-1112321-111111--112-2222222222--1-1--1--1111111-111111----------------------1------1--------1---1------- 12--112-1--211112112111111-111111111111111112111111121-111111111111111111112212211111--2112121111111-21161-1311----1-1----------1131------------1-1--------11------1--11------11442622243677817545---2- * d.36 Chalcone isomerase
[ 680] -------------------------------------------------------------------- 111-111111111111111-12112111111111111121-111--------------------1111111-------111-1--111--------1---1111-11111------11111111--1-11111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111--111111111111111-1---1111111111111111111111111111111111111111111111111111-------1-11111111111111-111111132111111111-1-11-1--1111111111111111121111111-1111-111111111111111111111111111111111111111111111111111111111111111-122111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111-111111111111111111111-1111111111111111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111211111111111--11111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111-1-1-1---1---11111---111111111---1---1-1- --------------1------1---------------------------------------------------------1-------1--------------------111-----------------------1----------------1-----------1-----------111---1-113111-21--2---1 * d.222 YbaB-like
[ 681] ---1---------------------------------11111---22-11111-------------1- ----1--------------------------------------------------------1---------------------1---------------------------------------11-----11--1-----111--1----------------------------------------------1111111111111111-211111111------------1-------------------------------------------------------------------------------------------------------------------1-------11112-----1--1------1111------1121211112111------------11111111-1-11111111111111111---11111------------11--111-----------------------------------------11--------------------------------------1-------------------1-----1222122--1------1--1-2-122111111-----------------------------11111111--1--------------1-1-1111111----11111111111111111-11-111111111111111111-111111111111111111111111111111-111111111111--11111111111111111111111121-11111111111112-----------------1-1111111111111111111111111111111111111111--222222-------------------------------------22111111121-- ----211---1----1-------111-------1-----------------------11112------------1--------------------1--1---1----13153569523534455974A2BR6178D2574A46544663345266514411121221M64613214422424242897F-C57855453 * b.102 Methuselah ectodomain
[ 682] ----1--------------------------------------------------------------- -23-----111-----------------------1---------11----------------112--112-----2----1-2-----------------3---21121---------------------1--2-13331---1---13------------1----554----------1----------111111111112121112121111111-111111-------311111111111111111121111-11-11-11111111-1--111111111-1---111--1-1111----------------------1---------1--11122--11211211-1--2----1-111--111-1-1--2611------12232-1-211-111111111111-21112111-21-322432346432-1-11-12----22-22222222111--2-1--------------------------------1-------3221221212222212222--3131212-----312---241211-3----21-----------14-11--162144111-2-331---2--1-231-1--------------------------113-----221-22-1-11----1-1--------1--------31111112222222322-2222222222222212211222111112222222222222222122122321-122222212222---------------1122221---22222221--------------3-2442-1212-221----------11212222231145-111-11---------4----111-------------------------------1-----121--1111-41- ------1-------1111--111132-221111---1111-11212121-1-11-1------------1-1-----------------11--12---1---1111-----412121-111111151-21472-2121--121111--1--1--21--1----1211--------1-----------11--1-1--1--1 * c.133 RbsD-like
[ 683] -------------------------------------------1------------------------ -----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1-------------------------------2-----------------------------------------------------------------------------------------------1---------------------------------------------1---1--------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------1--------------------------------------------1--------------1---------------------------------------------------------------------------------------1------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------1--------------------------------------------------------- ----221-711133223A42245381454142311126461572214412-1422511142221221-1-21211--11121-111-1122436373474-31-42-1-4N649DAA42373B7JD3G2U*F5BBO56269-775387-8841H4BA57598-23-24164164--12-31--11311-57-12232-1 * b.110 Cloacin translocation domain
[ 684] -----------------------------------------------1-------------------- -------1-----------------------------------------------------1--------------------------1-----------------------------------------------------1-----------------------------------------1------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------1--111----------------------------------------------------------1----------------2111272241532213222-6665433121214--22---1--2------------1------------------------------------1--------1-------------------------1111-------------1----1------1---------------E7--3597BCA9AA877-878E877B7BA79777777B891335DA449AABBCD98C69A82425562--58989A97A999--------------1--1------1--------33322-3--1--33331325-2332-132-------------------11---31111111111111------------------------------------------------------------ ----------------------------------------1-------------------------------------1----------------1--------------------------1----------------------------------------1------------------------------1---- * b.167 FimD N-terminal domain-like
[ 685] -----11-111111-1-------1------1111121111111-------1-111-12--1---1--- 2-1-----111---------------------1-----3-1------1----------------1-3-1------1-----2-------------------1--111-3------------------------1----------11-------1-------1-----------------------11---1-----------------1-2211-----1111-------2--111-11-11111113----1------12--2211------1-------------------------------------------------1-1-------------11----1-21-1----22--1---2-----------1--------1-4111-11211-11111111111---2--2-254--23312134335431--133411--122--------1-----1------------------------------2--11-155362332323111-22221111-122-3555------1-11--2-441------12----------1--1--1---------1-1--------------1----------------------------------11--1------------------1-------------3-21---3226366633-233356533326433333423313--13-3221333332322232222221------------------------------221211-1--1-11111-----1----1-11111411-3231-221-----------1-------111-------------------1-------------------------------------------2---------1-- ----1---2--1-111522311222221122331112212112111111421221122111111-2----1---1--------------1--5--11----2---4-35-36426-1---212-11131173-115-1-111---11---3----1-333311211374433A212--17111--2--123132-11-3 * c.122 L-sulfolactate dehydrogenase-like
[ 686] 111-11-----------------111111211--1---2111121-2222332111111121111--- --2--11----11-----------1------1----------------------------11----1-11-----1-----11--1--111-------------111-----------------111112131-2---2-1111-21-1---1211121212---2-11-111111111111-----1-1--111111111-1111111-1111111---1-1-1111111-133333333333332111221-1-11-1--1111111211121222111----11111111111111-------------11111111111--1-111-111-------1---11--1--1-1--1-3-11-1111-1---3------------2121-1---------------1---1-13--21---32--------22-2----2-------11111111-----------------------------------------------1111111-----11-2------111121-------1--1-1-12-11------1----------1--1113-----32--1-1-222-111--1--112------------------------1--11------1----------11--------1-------------1111-12-111-1111--1--1111111111------11121--1111111111111111111111111--1---------------1--1-----1--------1--------------------------------------1-------------12321311211---------------------------------------------------1-1-------11----------- ------2-3--111-32121--22123--1----------------1-111222-1111112----------------------12------2-1----1-1-----22172321122121111111312A1-22311112111111111121311122121-52313122113----1322111EPNe1a7--12211 * d.290 AF0104/ALDC/Ptd012-like
[ 687] -------------------------1------------------------------------------ ---------------------------------------1----1----------------------------------------------------------------------------------------1---------3------------1----------1----------------------------------------1------------------------------------------------------------------------------------------1--------1--------------------------------------------------------------------------------------------------1--------1-------------------------------------------------1-----------------------------------------------------------1------------------------------------------------------------------------------------------------------------------111111111111111111--------------------------------------------------------------------------2------------------------1-----------------------------------1------------------------------------------------------------------------------------------------------------------------ -1----1-1--11-2-1-----------------11----------------111------11-----1-----------2---1-------1---------------21sJSHQoE445545497365Dp41A6A4443A-46644455r5415VB8H4124G7U899JMIH76-----1----2----11--1---- * f.7 Lipovitellin-phosvitin complex; beta-sheet shell regions
[ 688] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------2----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111---1-2-2--1-------------------------------------------1244522-12---------------------------------------------------11111C678C85999699EFFEDD6C9IA3974-185533221C61111--1----23-------11-721----2------------------------------------------------------5721---22--11112121222212112221-1-12----11131463383445335343-43334453344333333343346233233335453453433332343333331111121111311-22----------11--1222222-221222221121111-1------------------------------1111222222222222434343333333------------------------------------------------------------ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1---- * a.155 H-NS histone-like proteins
[ 689] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111111111111------111----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2231662-411-55433333333343333333322332222223333333333333332333333333133333333123333333333-4433233333232442-4D48785446344334266374Gj4-7753424544534433353261444444544462E47644341331733234AB7I3F73566541 * a.240 BSD domain-like
[ 690] ----1------------------1122-1---------------------1--1-------------- -12-3--1------45332-23--4122222346763588-2-4----------1-----22----45142------------1-1114411----1---211---1----------------3---1-----------------12-2--1-----1----1-1-1---------------2-3--------2-1-3211-11223121---11131-12---------121-----------------------1------11----------------1----------1------111111-111111----1-------2-------------------------------------1---------1--4112-----212121--11112--------------4--4--1-2-----221-1121-----11-11-1114---------11--2----1---------------------------1-3---1-21-------1-1111-2142223--53445--22-211121231442-2---1-----1---1134--221--121--1111-314-112--111122-3--1--11--------------------11--1----21-------2------1-------1-11------11--1-11111221111-1111111111111111112-1---111-1--1--11-1111-1221--1-2------------1--------------------11--------1111----------2-1121111-121222------------21111111111111111--------------1-222222----------------------------------------------11-- ----1-2-3-1-122-1--1223223133332223232122342111-1-2135-1-12111-----1---------------------36-1-2----2--1--1--212----1311121143114-7A2-2131-221-21121-1123233111-2-212121------1-11223--2222134-351-112-4 * c.150 EreA/ChaN-like
[ 691] ------------------------------------1------------------------------1 ------------------------1--------1-1------------------------------------------661N-----------------------1-----------------------1---11-------------11-------------1--21-1------------------------------2--22---------1-2------2----------------------------1------1-----BB---C-EI3311---1---688EFEHHFGDFID-------------3---------1--D*-------c-b-A---6D5---2--23---2-------------1-------------------------------------------------------1------------------1---------------------------1----------------------------------------------------------------------------------------------------------------1-----------1----1---------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------11-11-1111----------------------------------------------32-------------------------------------------------- 231134--3132221-2-----------------------------11--1-1--1-212121---1-------------------------2--1-----21----1-16373234221--334212-2F2-325221-43222121214113-1343----1642332A112---3-1----13125-32-2-211- * b.109 beta-hairpin stack
[ 692] ---------------------1----------------------------------1-------1-1- -----1-2223---121-----1141-----1-111-111-1121------------1--3---3-871---111111----1----------1---------13-22------------------1----------------1--2-1--2------------143342----------------------------------------------------1-----------------------------------------------------------------11111-11111--------------------------------------------------------------------------------212221-1---1111111----------2------1---12-211211111122---1-222121-22---------------3----------------------------------1-2222-222222-222222--2222-32-----2----2-----2----2-2--2-223--------------111-----------131----------62--1-1------------------------11----1--311323231132223212213---1-1-------2-23212-222-22211-2---223-21222------11132331------------1---1--2----2-322222222222--2-------1-11-2-2111---1----1111---------21-2222----------1------------111111111111112111111212--------222222-------------------------------------------------- ------1-----321427474748E9C11121264321316221219325441132553111-11-11-11111111-11-1111--12-2122422122122221--213---------1-1-21112363-229--3251131-11111-11--211--112------1----1---2-----21115-2--33441 * e.62 Heme iron utilization protein-like
[ 693] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -2--115-32----1-211212121-1111111112-----111111111111-11-1--111--1-1-1--11111121111211-----221---1-----11--2617CAGHF58899A7BHA7K6k*D5QEQ9794C387869615CB2K6CAB96A918334436611741---11---1-111112-2-24-6 * d.266 Hypothetical protein MTH677
[ 694] ---------------1-1--------------1----------------------1------------ --1--1-1----------------1------11----------------------------------------------------------------------11-1--------------------------1-------------------1--1-1-1--------1------------------------------------------------------------1-----------------11-1-------------------------------------------2-2----------------------------1-----1---11-------11--------------------1-----1-111------211112111111111111111111-2112211111--11111121112211---111111111111111111---1-1-1----------8-------------------1111111111122112-----22-11111-211--1-1-----113222222211--1---2---------1------2----1111111-1-121---------------------------------1111--11---------11111---1111-1--1----1--11------111111-1111111111-1121111111111111111-11--5711111-11111-1111--11-1111-----------------------111111--1222211111111--11111111-1-2--1--1111----1----1------------1-------1-----1-1--------1-1-------1------------------------------1------------------ ----3-1-----111223434443443111111112121111123B64354233223-E112321111133111211-112333231--2322113-111223242-1763123632111--11211217F1-312111-11112-21--1212131232-11136132111123-13111126127Y93651165651 * d.124 Ribonuclease Rh-like
[ 695] 2212121222222112222222221----1--111111111111111111111111121111112-22 111-4---------1-1-----------------------1111----------------21----1111-------------11111----------------1---222222222122222--------------------1-1-1111111111111111111111--111---1-11-22222-----1---------------1111-1----1-----------12----------------------1--------11--111-1--1------------------------------------------------11-------------------------1--12--21211-22-------2121111-------3----112111--11-111112---1--2-1211--1111-311-23----11-21111----------------112111-------1111111111111111111--11--111111112111111122421111112172231--11111-11---1--11-1---1111111111118111-22-222242112-3333334331111---211122111112222222222222221111111111-111113311111111111111---1111------22111111221111121-211222122221211111233221111222222222212222211121111112111111111111111-----11111111-111-1-1----1111----------1122221121111111111----------22222222222222----------------2-222222----------------------------------------------1--- ------------------1--1-1322-------------------1--22343----------11---------111111111------------111----1-----------------------------------------------------------1---------1----------11-------2--11- * d.333 UbiD C-terminal domain-like
[ 696] ---------------------------------------------------------1---------- 313-------------------------------------------1--1--111--1---------2--------------------2211-------1212134-2----------------1--------12----1-----221---1-------1-----7111----------------------11--------1-----------1---1--21---------11--111------------11-----------------------------------------------------------------------1--3-------1---1--1--------1-11-221--3-----------2112111-----325113131232323232322222-3222252432--2112-25321-114-11-11--12--1--------2222--2--------------122-11-1---1------11211111222132311111--762222221171113----4253113544142341-1-12--1-111--2244321-111-12211---3-322-1-443423-1---------------1----1--2211---131222113555525354463344612---2732------22-2-221-1-1-1--1--11-----1----11111-3231-11-11111111111111113---111---233333333333----------2212311-------------2--1112121-1-2-23221211--13-21-1---------23222------12--2255355-1111-1---2----22-11-1-------------------------------------1---12-- --------2----11--------211-----1--1-----------------1-------------------1----------------2---2--------------1-211211-----------------------------1------1----11---12---1------1-----1-------11----1---- * b.163 Pseudo beta-prism
[ 697] -------------------------------------------1--4312--2--------------- ----2----------11----------------111-----11--------------1----214----2----------1-------DDA3-B------2--2454-3---------------------11---12212-1-2-13-41---1--------111231311------------11----1---11111121-11-11121----112-1-3--111112-46-111111111111111--11111-22-------11221----------------11--------------------------1---1-1--21691111113415412221-1232-11111-211---1-1---11------3--1-----1-4322--21121----------1-11-12--211--1---1-3--121-1--112-323251---------------11------------11---1-11-11-----1-----1----1-12111----11--------2213121--1113----2---2-1-3--1-3------------121---1-41-42214-2414321-121-212--3-11-111111---------1---2--1--1-11213---1-2131-1112-22125----------------13-11111111111-11-111111111111111-21122-------------------112111111-1-1111--111-----11111-----12-1-------------------------1-------12-1111-122---------1212------211221---------1-----8-23----------------------------------------1---------14-1 --1-1---------4-21--1-111----1111---2---------53--11-1--121232-----------------------1------21----------1----321212121111111331214C1-21211112-1111111121121111-11--11--1111--1--1--------5242-11--1--1- * a.283 ENT-like
[ 698] ------------------------1-----1------------------------------------- ----1------------------------------------------------1---------------------------1-1-------1--------1--1-----1----------------------------1------11121111111111111111111111-11111-11111111111-11211111111111111111111111111121121111111111111111111111111111111122111111111111-11111111221111111111111111111111111111111111111111111111111111111111111111112-12111-2111-11-1-1111-11-1-11111111111111111111111111111-111-11111111111-1111111221121111111111111111111111111111111------------------------------11111111111111111111111111111111111111-11111111111111-1111111111111111---1111-1-1-1--------111111311111111---------------------------11111112211111111111111111111111---1111------21111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1-----11111111111111111111111111111111111111111111111111111---------11221111111111111111111112111---1111111--------1-1----1---11---11111--1----1--111-111--1- ----12--121----1---1-1------1--------212111-------1-1--1--1----------------11--1------------------1-12---1--52-----11-31----41-------1-2----1----2-1-----2-2--2--1--1-1----14-11121811211211-1271111112 * d.193 Hsp33 domain
[ 699] -----------------------111113121---1111111112112-111111111111------- -1211--1111---11111-11--111111111111-111111111-21---1111-1--11111-1111--------1---211111111111111--1--1111112111111111111111---------1-11111---1111111111111111111211211121111111111111111111-21333333333334433322223333421121111111113211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112222222222222222222212122112112211222212211111111112----------------------------------1-----------------------------------------------------------------------------------------------------------1----------------------------------------------------123-3122112221232322421222221114--------------------------------1-------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111111111111111111--11-11111111-1111---1111111111111- ----1------1-11-------------------------------------------1-------------------1-1---------1---1---------------31111-21232222611525I33546222-2214212222511114211122--2L15134--11-11-----1--1-1-1-11--1-- * d.320 YojJ-like
[ 700] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----A94---1-122-----------1------------------------------------------1-------------------------------------4342FHDEI78464786VH3L7g*D3QHU3777C78A828656C54H895874985453394252334-31-8---1-4455-511-1111- * a.14 VHP, Villin headpiece domain
[ 701] -----------------------11112213----1-------------------------------- -------------------------------------------------------------------------------------------------------1--1-2-----------------------------------------------------1----11---------------------3333333333333333343333333333333333333333223333333433333233443331111111111111111111111222111333313311111111111222212212112111133311131--------------2---1----21-121--23333-221-111-1---2-2------------------1--1-----------------------------------------------------------1----------------------------1-----------------------------------------------------------------------------------------------11-------------1---------------------------------------1-----------1-------------1----------111------------------------------------11----------------------------------------------------------------------------1---1----------1------------------------1------------------------------------------------------------------------------1---1- ----1-2-114-----211---1-1-23311-11-1-1111112111-211322-1--32231-1--2--1--1----1-1--1------2-2121--112---12----54245333222462BA1528d2292913428-2453124-413C44225113-2112A3231243--1-3-113-436-252---1271 * a.281 YheA-like
[ 702] -------------------------------1------------------------------------ ----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1------------------- 21----2-1---111-11111111111221111111-11111111111--211111111222---1----11---11-112-----------1----------12--3-1AC9BCFECC7ABA9DEFMDR*A5MAG98DA699B6ADDD68C8BCE9572254665343651153----------2---112------- * a.291 MG296-like
[ 703] -------------------------------------------------------------------- -1111-----------------------------1--------1--------1-----------2--111-----------1---1--21---1--1---2---4-2-----------------1--------1-11111---1-1-2------11---------1-12-------------11----------------------1-------------1---1-----31--------------------1-1--------------------------------------------------------------------3----1-12---2112------2-11------11-1-------------3-12----31-7-111-2-1---------------2---1--2---2---112-2-1----2----211111111---------1--2-11--------------------------2-44-1----121-34113237455533228666263513221--1-22-1--31--2---2----351112--1----22--1----3--2-421213-22122----331111----1--------------------111-12----1---1-11-----------1---12-1-------3232221223153554-32-524424436322132422134DD21513421434344433422-223-2-143464444556--1----------1-121----11-11--1-2-1111221---324444223324323-311---------12121131131222121112--3334434-----------11----------------------------------------------- -----------------------3-2-------------------------------------------------------------1---------------------------------------------------------------------------1------------------------2-1---1---- * d.373 gpW/gp25-like
[ 704] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------ 2--1A63------------1-----1------------------1------------1------------------------------1------------------31GQCDDFC49398985HMCIDXrC2G9H7987AB8B539582E34OB68886E66566-N65MBD33--3---1-3-11-2---------- * g.77 Resistin
[ 705] -------------------------------------------------------------------- ----1-----------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------1----------------------1--------1------------------------------------------------------------------------------------------------------1--------1---1-------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------- 2111322-72422233332333334333333344443544445444222222222221222222334313322123333353333342215335332333342121-252546446856A6655E75A4PR4-C5A4465C4484456634447554333-33533223233653222382423243552442312123 * d.135 The spindle assembly checkpoint protein mad2
[ 706] --------111111------------------1---------4------------------------- ----------------------------------------------------------------------------------------------------------1----------------------------------------------------------------1-----------------------------1-1--11------1-1----1---------------------------------------------------------------------------------------------111---------------------------1-------------------------------------1-1------------------------1----------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------1------------------------------1----------------------------------------------------------------------------------------------------21---------------------------------------------------1----------------------------------------------------------------1----------- *2-1-22-6311221-12-311-21------1111--------------111-1-11--21-----1--121-----------------2-11-1-1-1-1-11---14143647AO61-53454F3D17N3163812122217311211211V3--C*---1--1---13133--21-22-1-22432-342112114 * a.264 Duffy binding domain-like
[ 707] -------------------------------------------51--1--323--------------- -221232222222331111-12--1211111122221433-2-22123----222232----21111112-1111111-222------111---------1111111-1---------------11-1111111122233---1-1221223--221111112211122--1-----1----111--------111-11111111111------111---1-11-------12--------------1111---1-11-1---111111-------------------------------------------------------------------------------11--21------------------1-2111------223442-122333111111111-1-32322211121-1111223323331411122322222232222222211122412------------------------------11211433-12222222122122262222122324556-23314214245142311612223311-------1-33----2----------1-12121----1-21--311111111---1-------113141111-11---2------------------------1123-----------1-------------------------------222---------------------1------------------------1---------2-112----------------11111122231444432224344431111111111111---11111111-111122222111-----12-111111----------------------------------------------1121 -----------------------1-------11--------------------1--------------------------------------------------1---1----------1---------------------------------1-1--1--------------1-------11-----2---------- * a.88 LigA subunit of an aromatic-ring-opening dioxygenase LigAB
[ 708] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1---553-1--------------------------------------1--1--------1-1----------------------------------2-1--------921*BIDNK88873597F6384Gv7-82A2876A446727456885ICCD7G6BH3G541122B7CAD-55-B--1112D98-7--123111 * b.89 Cyanovirin-N
[ 709] --------1------1----------------11---------11111-------------1------ 111---------------------------------------------------1-----------------------111----------1-------11111121-1--------------111111111111-----222--111-111--11-11111111-1111111111-111-1-------2111111111111211111111111121111111-11111111121111111111211121111--------1-------------11111111111111111111111111111111111111111111111-222211111122121222233321122-221-3222-1-21-111---11112221-----1111121112-1122222122222-11121111--2-2222222212221121222221222222222222212221231-------------------------11-111111-222121111111111111221111-11122222112222222222222-2211-1-2--------111222--1-11111111112-------1-------1-321-----------------32113----1111-12-11--------------------1111-------111-----11--2-1---1----1----11------1-----1--1111111111111111-------1-----------------1-----1111-111211-111111-11111222222211121222222222222222221-1--111-1111-------1---2222222222------1-111-21----------1---------------------------1--------1-1 --------1-----1----------------1--1-----------------------1-----------------------------------1----------1--251221-21-------11--1-------1-------1---1-----1--1-11--1---------1-111-11111111-1112113---1 * e.74 HI0933 insert domain-like
[ 710] 11----1111111111--1-1111111111-11111111111111111111111111111-111--11 ---1211111112111111-1111111111111111111111211---------------22221212221-------1--11-----11-1-111----11--1-1-----------------11111111111111111121-121111111111111111111111111111111111111111---11--------------1--1-------1111----11-1-11---------------------------------11---------------------------------------------1----------1-11-------1-111111111111---1111111211--12-----1111-211-111-111111---3232311111111112-21111111121-1111221111111122-111111111111111111-11-1111-------------------------------1--------2222222222222222222222221112--1122621122122-112122121----------212-1211-11111111-111211111-----2-11-------------------1--------2-111-11-11111-1111111111121----11-------1---1--1111111111-111111111111111111-222--11-1111111111111111-1111111--1------------------------212-2---------------11111---112122222222222221222-----------1-11111111111--12123111------1-111111--------1---------------------------11122-1-----1- --------1---------1----1-1-11--11------------1-------------11--2------11---------------1--1----------1---1--311---1--1-1111212-1-784-2211-111-121112122-1-----1---1--11-----1---1-1------1--2-112--1--1 * c.39 Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)
[ 711] -------------------------------------------------------------------- 133----------1----------------------2-1---------------3-----1---------------------------------------6---723-------------------------11---------5-31-111---11-----------112------------------------1-12--1--22--4------------31--------332-------------------------------------------------------11131111111--11-1-11-----------------1-----------6---------------3-1251----------------3---16318--3323----11-----------4---2-112134---221---1----12---3---1---31--------5121-413--------------------------------1----------2-13----22--21---1-4-1--5--2281-3--74------4-1--32-11111112-----1-----1-112321-4----5-61--11---1---------------------------2--331---2-511-1--2--116-11-1----1---------157122222-22-32--32242421233331121132-143MQ-----25131-1732-21-3----1--233313333211--13-----------5-2-----1-2-----2-1----------3--3-3442----2-1-21-----------------------1-536343441212--------22-222----1--------------------------------------1-2 ----1---41--1----111-11-----1-----1-11--1-1---1-1---1----11-11--------1-1-----------------------------2--1---17------112211211-31262-1-7----11112-2-1------21---1----1--11---12----------1223-----1---- * d.231 Receptor-binding domain of short tail fibre protein gp12
[ 712] --------------------------------1-2------------------1-------------- --43B565113313-----------------------31-341324111211442-1211552124497A2533333322579-----111--------------------------------------------45555---54---------------------------------------------111333335642473456563352344221233322222221422222222222221121123111341112211114321124122265545252114111141161132222335443223662215661---1-1111111-1--1--257411-4A312---1-----1-----------------------111------------------1-11111-11--1-----11-1111-----1---------------------------------------------------------------------11-1111111--1111--11-------------11-1-----------------------------------------------------------------------------------------111-11-11111-1111111111111---------------------------------------------------------------------------------------------------1-----------1-------------1---------------------------------------------------------------------------------------------------------------------------------- -1------2---------1-21-1-1----------1-------------2-------------------1--------------------------------------1--11--------1----1-9A3-----------------------------1---1--------1--1--------21----------1 * b.100 Sortase
[ 713] -------------------------------------------21--11-111--------------- 111-311111111111111-1111111111111111111112121111111111211111--111-1111-1111-111111------1111-111---11122111-1--------------1111111111-11221111-1----1---1111--121111111-2-------------11111--1111111111111111111--111111111111121111111111111111-11111-11111111111111111111121112111111111111111111111111111111111111111111---1111--1-111111111111---111111-11111--11---1----11--1111-1111111111111111111111111111111111-11-11-1114111111111111111111-11111111-11111111111111-----------1---------------------11111211111111111111111111111111111111111111111111121-111111111----------1111------------1-212111--112-1-11--11-1--------------------11111---------1111---1111-1--1--------1------11112111111111111-111111111111111111111111--11111111111111111111----11-111111111111--11-----1111-----11111111111-11111111111111-11111111-11111111--------------11111-----11111111111111---1----------------11111--11--11----1-1------------------11 ------------436-11-1112-1-1---------------------22111111111122---11-------------------------11-------1------2----111-----------1------1-----1---------2------------1-1----2-------1----12----1----1315- * f.16 Gated mechanosensitive channel
[ 714] -----1------------------1-1-1122--1-------1-------112-1113---------- -----1-1111--1---11-11--1111111-21111-1------11-1-------1--------11---1----------1---111111111111--1111111112111111111111112111111111111111----11121-11-211111111111-12211111111111111---11----12--------1---1--131111------1111--------111111111111111111111-----------------1111-----------1--------------------------1----------21--111111111--1--111111121111-1-----111--11---121-2111111111111111111111111111111111---1--1-1121-222222122211222111111111111--------------111111111111111111111111111111111111111111----------------------------------------------1111121111111111111-122211111-122111------1-1111221--1111-----1---------2--12--22-212112322333312232233321312--13132------2----11------------------------------33311112----------------2-------2-111111111111---1---------11212---------------------11121-11111111211121111---------22332333333433322222222222---111211111111111111112----1-1-111--111-1--111111-1--11111-1-1 ------------111--1-----------------------------------------1---1-------------------------------------------1E1-----2-1----2---------------------1--1-1-------------11--1---1-1-12226-11211------43----- * f.57 MgtE membrane domain-like
[ 715] 11111111111111111111111111111212111122111111121111111222211121111111 -1--1111111--1---11-1-----11111-----1211-1-21-1-1----11--1--13--1111111---------1111-1--112---------3-1-31111--------------111-------1-111111212112212211---------11--112-------------2-11121----11111-11-1112-11111--112---1-11-1111121----------------------------------------1---------------------------------------1---------1-111-----------1------1-1--1---1111-1-111--1111---12------------22-------------------------1------1----1--1-----------------1-------------------1----------11-------------------1----111111--------------13--111-----2-----31111---11---2---------11-111221-121-11111-11111112111116511-----------------------------1--2-----------------------1---1111-------1-1---2333333344-3224343444333332332---131111-2121212221111214313332-------------------1-1121111-2-1---------------11121----11-2223241-1-1-1-1------111-----------------1111111----------1--------------1---------------------------11-21111111211 32--111-4112111--1----------1---------------------1111-----111--1--------------1-----1-------1---1-1-----1121211112212111111121216E1-112111111112122111211213111321311-2211323412119121122---111-1---12 * d.261 Hypothetical protein PH1602
[ 716] ------1------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------1---11------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------1---------------------------------------------------11----------------------1------------------------ 1---113-311122111211211211111232211111211111112111211111534332111111111111112121111111222-3212111122211212-1-24BA5EA86A66453GE4I2Z*F-I6G5955B585365434573F7D84526737442543A4841111-----1121-2131---1112 * a.227 ERO1-like
[ 717] ---------------------------2-1--------11-1---121-32-2--------------- 2---121----------11-12--1211111-2--1-121--1---12132--1--1--------------1---5331131-11-1-2121---1---4111---2-1---------------1151-3-141-----1-1--------1-----------11-1-1-----------------------11--1-1----1------------1--2-----1-------------------------1--1------2211111---1---1---1-------1111111111211--11----1----133---111---1--111-1---1-1----11-1---3--13-4311-1-1-------23---3----631431--111-11133----------2-11----22-31-2332--2----2-1---1-1-1-----111111111-----1-------------1121-1111-11-1-2---1---1---------1-------11------2-------1----111-112111--2---11-123222122-1--23123-22111111--327-25141-11---21-----1---11-12221112----11-1212-----1-1--111-1----1-----------1------221111-1111111111-111111111211111111122222441111111121111111111111111--312112212222----241231---1----111-1---11-2121-----------211-1-111---12---11---------1-11-1--1------1-31312221111------1111--------3-2-1----1-1-2------3-----------------2--- -----11----------------111------------------------322311--1-------------------------------3----------1-----2-44111121-12111111-11151-111-11121141-121112-211-111111111111121112--2-----1------13--1111- * a.265 Fic-like
[ 718] -----------------------------1-------------------------------------6 ---------------------------------------------------------------2-----------------------------------2113411-----------------------------21111---1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------411-1----------1--11-3111119N--1---------------------2--------141-2--1111-1-2-----21--13---------------------------------------------------------------------------------------------------1----------221------------------------1--8--------------------------1---------1-1---------------------------------------------------------------------------- ----1-1-1-----------------------------------11----------------------------------------------------------------QKFDBL79874695B75A5Dv8-D6C4656989AA27956847C7D9B7ARK232218232--82------------------------ * g.75 TSP type-3 repeat
[ 719] --------------------------------1---1111111-----2------------------- 123-2---------11122-21--2122222112221111-1-1--25----322222--11122132221---------111--1----------1---1---2-1----------------1---1-1----2-11-----2---------------------1--1-----------------------211111112-112121112232111---312122222141--------------------21-111111-111111-----111-1----------------------------------------------1--1111112122----1---12112112-41112-1--2---1-1-----2111-----11423--13222322222212222-22131111-41--11211222111--2-1--11111111--------111----1-----------------11----1-1--1-1121-122-13233311123222112222125212124--33411111-11111111---11---------2-11-1211-11-1212111----1----1111211--------------------------1111-1----11-1111111111111111111-------------111--211111111111-111111111111111111121212111111111111111111111111111--111111111111---1-1-1-111--1211-------------------------1122212223122221111-------------111111-11111122223111-------1------------------------------------------2----------1-1 -------------1---111111222111111111111-111111111121--1--11----122----1--211------22212------------------------------------------------------------------------------------1-1---11-----2----1-----1---- * g.48 Ada DNA repair protein, N-terminal domain (N-Ada 10)
[ 720] 11----------------1-111----1----1-12211111111-1-111111121111--1----- 111--------------------------------------------------------------------------------11211--1-------------1-------------------11111111111----------------1-------------------------------------1-21111111111111111222222111111122111111122--------------------1-1-11-1---111111---222------1-------11---1---11111111111111---------1-1------------------111----11------1---11-1111--1--1---------------------------------------------1------------------211111111111111111111-11-111111111221111111111111111-211-----11111111111111111111111111111111111111111111111111111111111111111111211111111111111111121-1111-1111--111111111111111111111111111111111111111-11111111111111111111-11111------1111b-11111111121-11111111121111111111111111-111111111111111111111111111111111111111111-----2222111211111111111111111111111111111111111-111112--1---------111111111122111----------------1-----------------2------------------------------------1-- -----1----1---112-----2-1--1-1---1--11111--111---1--3---1-11111--------1-----1-----------2--2--12--------1-----1-11-1-1--1321215--5---1-11--11-14-221---111--11-1---11---32-----11-6111-12224---------1 * a.195 YutG-like
[ 721] ----------------1211111111111111121111111111212411111121211211111-11 -------------------------------------------------------------------------------------1--------------1------1--------------------------------------------------------------------------11121----11111111111111111------111-----1---------111111111111111111--2---11-----11----1--1111--11111111111--211-1-1-22222222222221--111---------1111111111-1--111122112-----------1---11---11-1--------------------------------------------1--------------1-1------1-----------------1----------------------------1-2-------------------------11----------2--------------1----1-----1--------------1----------------------------1-------11111------------1-------------------------------------1---------------------------------------------1-------------------1-1----------------------------------1-1--2--------------------------------------------1------------------------------------------------1----------1----------1----------------1--1--1--2-- 1311311-311111131221112121111111112113332222112112213222121111111111111211211-1232222111114112241112121121111254635323313344384337S4-46523333254333333321A3344535533241423333421111F1121131111312212321 * f.40 V-type ATP synthase subunit C
[ 722] -------------------------------------------------------------------- -----------------11-1-----11-1----------------------------------------------------------1-1-------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------1-----------------------------------------------------------------------------------1---------------------------11-1-------1-----------------------------------------------------------------------------------------------------1---1---------------------1------------------11---1-------------------------------------------------------1------------------------------11-------------------------------------11----------------------------------------------------------------- --------------------11--1----------------------------1--1--------------------------------------------1------1----------1-------1-------------------------------------11---------2212---95****1*b------1 * b.142 DNA-binding pseudobarrel domain
[ 723] -------------------------------------------------------------------- ----------------------------------------------------------------1----------------------------------------------------------------------------------1------------------1-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21--321-31--1224442423433122213323332444444324342343334453433444443314323431433334433412222243343343331452-33263743434482154I7285ILA-6693425845674436337243343531-2-3226467243312229122226545554-13342- * a.17 Cysteine alpha-hairpin motif
[ 724] 11-1-1111--11111-11---1-11111--111111111111111121221111111111-----1- 211-1--11111-111111-11111112111111111211111111111--1111111--111-1111111----111----11111111111111----1---1-1-1---------------1111-111111111111111111--11111--11111111-111-111-11111111111-11111111111111111111-111111111111111-1111111-11---------------1--------------------------------------------------------------------------11-111111111-111111-111--1---1111111111111----1-1-1111111-----1111111111111----------1-11111111121-111111111111-1111--2-----1111111111----1111---1111111-------------------111111-----1111111111111111111111111111111111-11111111-111111111111111111111111-11111111--111111111211111122111-1-------11111111112111111111211111112111111111111111111---1-1------1111-111111111111-11111111111111111111111111-11111111111111111111111-1-111111111111--1111111----111-1---------------1111111111-1-----111--------------11--111111111111111----------1111--1-111111---------------------------------------111-111-111 --------1---1--1-----------------1----------11--1------------------------1--------------1------1---1------1-3----2----1-----------2----2---------------2--1---1--2-----------21-2112--1--3--1121---1-2- * c.145 NadA-like
[ 725] -------------------------------------------------------------------- ---------------------------------------------------------------------------------1-1-------------------------------------------------------------11111111111111111111111111-11111-1111111111--11111111111111111111111111111121111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111112-12111-2111--1-1-1111-11-1-11111111111111111111111111111-111-11111111111-1111111111111111111111111111111111111111111------------------------------11111111111111111111111111111111111111-11111111111111-1111111111111111---1111-1-1-1--------111111111111111---------------------------11111111111111111111111111111111---1111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---1-----1111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111----111111--------1-1----1---11---11111--1----1--111-111-11- ----11--211------------------------------------------------------------------------------------------------131---------------1---11----1-1----1---------1--1-------------------11118111112-----31111111 * g.81 HSP33 redox switch-like
[ 726] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- k---22-----2---1--1-----------------------------------1----222-----------------------------------------333-------------------------------------------------------------2---22---222723221e***-*N------- * g.79 WRKY DNA-binding domain
[ 727] -------------------------------------------------------1------------ 111---------------------------------1---1--1-1----------------1----1--------------------------------1111-1111-1111111111111------------111-----1------------------1---11----------------1--------111111111111111--111-1111----11---------------------------------------------------------------------------------------------------1-------------------1----------------1-----------1--1111----1----------------------------------1--1---11-111----111------------------------1---------------11--------------11-2------11111111111111-1111111112121--11111111112-11-------1-----1--------1--11-------------------111111---------------1-------------11-1--1112-1111121111111111111--11-------------------------------------------------11-------1-----------1-----------------------12-----1111--1------1----------11--1---121-11111111111111211-------------211111111231111111111--------11-----------------------------------------1--------1--- ----411-41-1211-----------------------------------------21-----1-1-------------------1--1--------------112-1-6A7A57C8433345474375Fa61968334363546333334335479577964547456-I3611122----2112112-5-1-321-- * d.178 Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
[ 728] ---------------------------------1-------------1-------------------- ------------------------------------------------------------------1--------------------------------1------------------------------------------------------------------------------------------------------------------------1-1----------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1-----------------1--------1---------------------------------------------------------------------------1------H--1111-------------------------------------------1--------------------1-------------------------------------------------------1--------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------- 2111222-2-1-22243333333434344333333323333333334344444533423333222222-2222222222222222222223232332222212222-43256844454334354DC473Ka5-B69332383467445334237284642343223223232234--1-------43343222-24263 * e.43 Subunits of heterodimeric actin filament capping protein Capz
[ 729] 111112222222222312-1---4333124231121111111124245-3333111111112221-24 111-132233422322122-221122222222222222331111222122223233121111111221212-------123111----------112--111111312211111-111111111-1-1-----1143345--111-----------------------11------------31111-11211111111111111111111111111111111111111111111111111111111111111-2-11-1---11111111----1111121121111111111111111111111111111111---1111-1-2323221121211-331---1122--11114411-111-1------1113---------11--2------1-------------1111111111--1--1--1----------2---------1111111111111--------------------------------------------------------------------------------------------------------------121111--1-----2131111121111---2----------------------------------------------------------------------11---111111111111-1111111111111111111111-----1111111111111111111111111--------------1--------------1------------------------------------------------------2--------------22111111111111---1--------------211-------------------------11122222221111 ----------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------- * a.76 Iron-dependent repressor protein, dimerization domain
[ 730] ---------------------------------1--------------------11--11-------- ------------------------------------------------------------------------------1--1------1131-3------------------------------1---------------111----1-1-------------------------------------334----------------------------------1111----------------------------11-------11-------------------------------------------------------242265555555556464443446252122335445844841433322---2------------------1---1------------------------------------------------------------------1------------------------------1--------1----------------------------------------------------1----------1----3-2--415222--111111151----1-13-----------------------------1-------------1-111---1--------------------------------------------------------------------------------------------------------------------1---------------------------------1-----------------------------------------------------2--------------2---------------------------3223333333-1-- 1211121-3112212111111111111111111111111111111111111111221111111111111111111-1121111111111-1111221113121111113222623353121122242629T5-5361121322221222132-722322126111215111131112317121411222221221212- * c.96 Fe-only hydrogenase
[ 731] ------------------------------------------------------11------------ --------------------------------------------------------------------------------------------------------1-------------------------1--------------------------------1--112---------------------333111111-211221121333131131232---------6I------------------------------------------------------------------------------------------1533-3334334-3-3-55211112----1-1144221313112221---------------------------------------------------------------------------------------1-----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------b-------------------1------- ----679---1-122-111111112111111111111111111111--21111311121111-------------------1-------12-112--------1-1-5339344441643346386364EZ81547345355683365345424551463224651131135458----------5325134--6434- * a.41 Domain of poly(ADP-ribose) polymerase
[ 732] ---------------------------------------------1---1------------------ -11------------1--------1------------------------------------------------------------------------------11-------------------1------------------1-2112----------------1--1-----------1-----------------1----------1----------1--------------111----------1---2-----------------------------------------------------------------------------1-11-1--1-------------1---------------------1--------1---------------------------1-----11-----------------1-----1----------------------------------------------------------------------------------------1-----------------------------------------11----2------------1-------------------------------------2---1---2-----------------------------------2-1----------------------------------1------------------------------------------------1--1----1--------1------1-----11-1-------------1-----------------------------1----------------------------------------3--------1---------1----------------- ----346-221132212345464323243553423343344442223122224422222232232223223232342232345523233-2321261122-21542-2-2E4543A41223132974415C4-36421226154426242445313342125465214363373411235212213328444211832- * a.252 Mediator hinge subcomplex-like
[ 733] -------------------------------------------------------------------- 1281123223232311211-121121111112211111222-1-3111111-223121--1-2----3423-----------1--------1-----------111-1----------------11-112111112--43---34111111--1---------1-3111------------------11-21111111--111-11111211211111221121------43-------------------------------------------------------------------------------------------1211----------2-------2-2--2---122222211-3112----2-11--------223221-1--11-----------1-3211212--21-122-11-21222-3------32331-111111111-----11---------------------------------21-222123223322111132442222232231424--1111121111132122112111--------111111--1------------------1----1-62-2---------------------------1111221-1-11111111111111111111---1112------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--12---------11111111111111111111----------1111111223111121223---------11111111112212221222222331111--1---------------11-------------------------------------1-- -----------------------------------------------------------------------------------------1---------------------------------------------5-------------------------------------------------1------------- * a.180 N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
[ 734] ------------------------11111111----------------11221--------------- 11------------------------------------11----------------------------1----------11-------111111--1---111111111--------------------------11111---111111111111111111111111111111111111111-------111111111111111111111111111111111111111111111111111111111111111----------------------------------------------------------------------11111111111111111111111111-111111111211111111-1--11-1-------------1---1-11--------------------1--1--11--------------111111111111111111111111-11111211111---------------1111---------------------------------------------------------1111111------------1-11111111111111111111111111112111111111111111111111111--222111-11111111111111111112111111---1--1------11--11-1111111111-1111111111111111111111-----111111111111111111111111--111111111111---11111111111-111---------------22112211112111111111111111111111111111111111111111111--------------111-111111----------1111-1-1111111111112111111-----------111 -----1--111111111121111111111111111111111111111111111111111111--------------------------112111111111---112111-2---1-----------1----------------1--1----------------1-------12411121A111224332131------- * c.105 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
[ 735] ---------------------------1----------------------------1----------- --------------------------------------------------------------------------------------1------1--------------------------------------------------------------------------1---------------------------------------------1-------------------------------------------------------------------------------------111---1------------------1----------------------------------1-------------1-------------------------------------------------------------1--------------------------------------------------------------------11-1------11--------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------1-------------------------------------------------------------------------------------- --11------------------------------------------------1-11-------------------------11--1-----------------1-----2-22222-11--222232252F2-224-22222224-12--2--324312------111111--------I-----7***-**------- * a.13 RAP domain-like
[ 736] -------111111111--------111---------------------111-1--11----------- -------------------------------------1---------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------- ------------F-14---2------2-111--------------1-H--1---11-8-----161---4--------2---1B1----K-1-1-11--513K------------------------1--------------------------------------1---4-----1---2-2--5SA2-41--4P**- * a.262 PriB N-terminal domain-like
[ 737] -----------------------------1---------------------1---------------- ----1111111-1-11111-111111111111111111111---1---------------12111121111-----------------1111-1------21112111111111111111111111111111111--------------------------------1-1------------111--------------------------------1-1-------------------------------------------11------------------------------------------------------------------------------------------------------1------21111-1111111111111111111111111111-11111111111-11111111111111111111111111111111111-1111211------------1111111111111------111111111211112111111111111112111111111111111111111111111111111111111111111-1112-------------------111111---------------------------111111111111111111111111111111111--1111-1----11111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1-111111-----------------------------------------------111 21--11--521-------------1-1---------------------1-------------------1--------------------------1---------1--F11------------------------2----------------------1------1---2-1-1-14337233543464-436912112 * d.310 VC0467-like
[ 738] ----------------------------------------------------1--1------------ -1--1-1------2---1---2----22121-22-42412--------2--1--3-----2-----------1112111--2--1-111--3------------1-1-----------------------------------1---1---------1--------------------------------1-1-55555111123223-1-4412--3-11111-3----13111-212113133131---2-1----3-11--312223-2111-33222-1-1---------11--11233341122113------------2-112--231121121441111-251----2--11--1----1--------1211-------1-1-54311111111-111-111-21-11631111-2114------1-121-1113734314111111111--1-----111111111111--11--2------1-11-12-1-11--1----1------11-213--11------1--111-11--1-111---------1----1-1-1-1----1--------111---------11---2---------1---1-------------------------------1------1-1---------2-1-------3---2--55--1-2---4---214-1-411-----1-1-----11---121---------------1-2---------------1------------1--1--11-------------1-1-1------11----13-22-----------------211111------1--------2222--------------------1------------------------------1--21-1-- --------21----------------------------------11-------------111-------1--------------1--------1-1--------1-------21311----1-241-1-141-112--1--11---1-2--------------11----1---1---------------1-------1- * d.183 Major capsid protein gp5
[ 739] -----1-----------111----111--------------------1------1------111---- 111111-------------------1----------1111----1111----111111--11121-1111-----1------1-----1111-211----11112---2----------1111------------111-----1-1-1-11-------------------------------111-------111111111111111112---11111111---------111111111111111111---1--1------------11----1-------2---1-------------11111111111111--11------11--------------------11---1--1---1-1--1---11-12-1--1111-------111--------11111111111---1--1--31--211122143211---21--21-11111--------1--1--11--------------------------------11------1111111111111112221212112322--113--1--1-2-11-------2--1--------1--2-2-1-------------------111111-1----------------------1----11-1-1111211111111111111111111------1------1111-11-------------------1----------111--11-111-11111111-1-11---------122222222322---1-----1212--1-1---------------111211--111-1111111111111-111----------111111111111111111111111------1---------------1---------------------------11111-1------1 ----111-311-1--11---1--1-1---11----1-------11112---1-1----1-21--------111------1------1-----1--1--11-D1--1-1124332233121121212-436921522111-21132-111-12-1213111422331-111-22321-1-------1115--11122231 * e.51 Urocanase
[ 740] ------------------------1-------------------------------1----------- --11----------------------------------------1-----------1--------1--------------1---------------------1----------------1111----1---1---22222-----6775668655566567655569874232433234422-------1----------------------1-------1------1-------------------------11----------------1---------------------------1----111111-1-----------1---1111111-1---11-222-------------2------------1------------12-22---22222-----1------22222122----1----1-1---------22-22222----------------22----------------1-------1---------------------------------------------------------11----1-11----------1-----12------1---1------1---------------------1-1-111-------------11------2221111111--1----1-----2-------1-------------1--------1--1------------1-----2111122222121211-------------------------------------1------11-1111-11-------------1113-1---------------------------------------------------1-------1-------1-1------------------2--1----1-1---------- 11----1-62--1--2-221-21---211----11---------2-1--22-----1--111--1----1-11--------112------1--2-3-12--11--2---22232---13212111--136F2-215222-21-1-1422-1111-413422621311-121-6513--2--11--16-L-14242--23 * f.26 Bacterial photosystem II reaction centre, L and M subunits
[ 741] -----------------------------------------------1-------------------- --2------------------------------------------1----------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1----------11---------------------------1-1-1--1111-2-1----3--1--111-11-----------1----1-------------------------------------111-24111124444422346666154142221--1-12-1--1---3--------1------------31----------1----1-1-11-1-----13---1----------1--------------2-1-21--1-21-----1-----1-----1----11-------64-B2211223156743-1-131-433425311111222277FB72944543445334342311----21-1989999789A8---1-----------213----1----------1111111---2-5635814326523-374----------41412222212311--1-2--222------------1--------------------------------------------------- ----1--------------------------------111112------------1-----------------------1------------------------1-----2----2------------13A1-21---1----------------------1-------------------1----------------- * b.157 Hcp1-like
[ 742] ----------------------------------1---11111----------11111---1------ 11--1111111-1111111-11---111111-12111-111111--1-11--11111---113-1111--11111111---1------522313131------11-1--------------------11--11-1------141--15423-----------32--2231-----------------------12122-11-122-----11---11-----11------1------------------------1--1-----------------------------------------------------------------1------------1-------1-1--1--2-3-21-----1----------1111-4212214123121311122122212121--1------221-222521121111151--1------1-----------211---------------6-------1----------31--------1-----1-----------------------1-1-----12------1-------------22-1-1-1--1----11----1111111-------1---------1-------------1-----111-11----211111111211211111111--2111------13332321221111111-2312221111211111112111244112212121321121221221122211-222222222222--1-------1-11--1-22211211111---2-------1--1-111111111211--3111----1----2222111112222211-1111111------1------------------1-1----------------1--111------------1- -----------------1---------111---1------------1-----------------1------------------------1-----------------1--22-------1----------------------1-1--1----------11-1-12----11-1-----251111-5-14-22----42- * e.13 DNA primase core
[ 743] ------------------------------------------------111----------------- -------------------------------------------------------------------------------------------1--1-----11---1--1---------------11-1111111-----------------1--------------11---1-----------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------222211111221221122211211111111111-1121111122112212222212221111141111111111111111112221212223111111111111111111111111-1-1222111111111111111111111111111111111111111222222222221122111211111111111121-----------------1--1-11----1--1-1-----------------------113212122112121222221122212121221-21211------32222222222222222-2222222222223222222222222212222222222222222222222221-211111111111--11111111111121221111111111111111111111121121111111211212111111111111111111111111112222222222222222111--------------------------------------------------------- ----1----1-------------------------------------------------------------------------------------------1------2-11-------------------------------1------1--5----------------2-----1--------------2--1---- * b.136 SspB-like
[ 744] -------------------------------------------------------------------- -------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------1------------------------------1---------------------------1111-------------------------------------------------------------------------------------------------------------------------------------------------------11-----1--------------------------------------------1-------------------------------------11---1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----422-1---5532111233322222222-2221121221212112221121222-1222223222-2322323332323332321155313343333343689-513256788D5552463D63A4Gj7-88H42346464455645832B355643474422-81131322---------1-1223--------- * a.68 Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
[ 745] 11111111111111112111111111112-11111111111111111121222111111111112111 11--1------------11-11--1111111111111-11-------------2-------1----1221-------------1-1-----------------1-1111-----------------------1---11----------------------------------------------1--11-------------------------------------------1-----------------------------------------------------------------------------------------------------1-------------------------------------1-1------------------------------------------------1-----------------1-111-----------------------------------------------------------------------------------1----------11----------------------------1-1----------------------1-------------------------------1---------1-----1----1111----1----------------------------1------------1-----------------------------1-------11111------------------------------------------------------------------1---------------------------------11--------1------------------------------------------------------------3-- 2111233-411111342322222222322222323222222222222233222322222323111112-1111111211111111212345424532223312233131282333321233233152514H4-2262322212421232221-11312235D-442112-694731221H1112321223431122221 * a.235 ATP-dependent DNA ligase DNA-binding domain
[ 746] -------------------------------------------------------------------- ----------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1-1-11-----------------------------------------------------------------------------------------------------------1-114---------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------- ----L87-21-4---------1-11-111---2311----------------1-22-211-2--1-----2-2-1-222111-11-----1----1--1------1-B4TQ6C99652222445E4384IY91D59225472584153423419457264782D743S66C6G81-4318--131123221113-1-24 * b.116 Viral chemokine binding protein m3
[ 747] -------------------------------------------------------------------- --------------------------------------------------------1--------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1-1-----------------------------1-------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------11------------------------------------------------------ 2223322-814-134121112211232111111121232323322111112211111111111111121112111111111-111122222122121112234221124245644476557556B8592Fa8-99B64865466566764754C677572342243223212173213252432-3222157232523- * a.146 Telomeric repeat binding factor (TRF) dimerisation domain
[ 748] ----------------1--------------------------------------------------- ------------------------------------------------------------------------------3--1------------11---------------------------------------------------------------------------------------------1----------1-------1-11-1-------1--434444----------------------C1-15D1131533--6814422211132344443334443343444433333333343333331113333---2A-----1-3-2-6---442---3-3--------------111-2121-------------------------------------------------------------------------------------------------------111111111-11---------------------------------------------------------------------------------------111111111--------1-11111-1---------------11-1---------2------1--------------1----1--1------------311133-3444354543-3233444443454333335433122213432333442324223321133213-222222222222111---------------2222121----2111----------------------------------------112-------112-----------------1---------------------------1---------------------------- --------1----------------------------------------------1---------------------------------------1---------------------1---1--1----13--2---11--11--1-----------------------21-----111---1---------------- * c.38 PTS IIb component
[ 749] -------------------------------------------------------------------- 1---1-1-------22222-211122222221211123572---211211---212-1--11121122312-----------2--------------------1--------------------111111111-1111------1-------1--------------------------------------------------------1-----------------------------------------------1----------------------------------------------------------------------------1-1------------------1-------------------111111111--2--1111111111111111111-213112-222-1111211211111121111--1111-----------1---112211111111111111111111111111111-1111------222122-----22111-----2213332--3311-----112----1----11----------21----------------121-1-11-----1------------------------------11-111211111111111111111111111---211-------------------------------------------------------------1-------------------------------111111222212211----------------------1112122222222222222253-----------1111111-1111111231221111111--------------------------------------------------------11-- ------2-1-21--1-34-2-1123222111111211231221122211222-51-22222212111-1-11-1121-111222121134213--11-1--9----------23-1--211--12211115--1--11121----2-1-1-1-3-32---1---112-11-------51------1-1------2---- * e.45 Antivirulence factor
[ 750] 11111111111111111111111111111111111111111111111111111111111111111111 -----------------------------------------1-----------11--------1--11-1-------------------------------------------------------------------------1---------------------------------------11-------2----------11-----1111---------1-----------------------------------------------------------------------------------------------------11---------------------------------------------------------1------------------------------1-----------------------------------------------------------------------------------1111112211111111111111111111111111-11111122111111111----11----------111-------------------1-------------------------------------------1--------------------------------------11--1111111111111-1111111111111111111111--111111111111111111111111111--111111111111----------------------------------------11-----1--1-1-------------------1-------------11112111111111-----------------------------------------------------------1 111112117321113111121111111111112121-111-111111111111111111-211111111-12-11111-11111--2321211211111111133511212-11111-123-413B1A2AK5-32A---67--222-11122112-11322122131512213111111F1112154441311211111 * c.9 Barstar-like
[ 751] 111-1211111111121-221322-111-2--1-111111321124631-12112111211---1--- -11-2-------------------------------1------------------------1------1-------------1----------------------------------------1--------1-------111-11-1---------------------------------------11----1111112111111111-11--112--1------------------------------------------------------------------------------------------------------1----1111111-1--111----------11--343--1--1-1111----1--11------1-11122123212------------11111111-1--1-------11--11-1---1------1------------1-11-----------------------------------1------------------------1-----------------1-------1----111111111------34412322-32112-1111-1-2211-1-122---------------------------111211111111111111211111112121----11-------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111---------------1111111111111111211111-111111111111111111111111----------21111111111111------------------11---------------------------------------------1-111--1- --22222-2312-------------------11-------------------------1-------------------------------------------------9411111121111-1121-516C1-21511--211111111112-11---1---131-13122--12111142121211111111232233 * e.56 YaeB-like
[ 752] -------------------------------------------------------------------- 111-------------------------------------------------------------------------------------111111111---1111-11-1---------------111-111-111------------------------------------------------------1111111111111111111111111111111111111111111-1111111111111111111--1-11-----11--11-----------------------------------------------------111111111111111211111111111---11---11-111111111---11-111111111121111111111111111111111-11111111111-11-111111111111111111111111111111111111111111-1111111--1111-111111111111111111111111111111-11111111111111111111-11111111111111111111111111111111-111111111111111111-11111111------11--------------------------11111-2121-111111111111111111111--11111--1---11111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-------111212222222212222-222---------11111111111111111111111111111--21111111--------11---------------------------------------1 ------1--------------------------------------------------1-----------------------------------------------------11---------------------------1------------------------3-------1-----2---------------1-2- * d.244 Cell division protein ZapA-like
[ 753] -------------------------------------------------------------------- -----------------------------------------------------------------------1111111-----------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------1-------------------------------------------------------------------------------------------------------------------1----------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3142-5-222-4--33222-------------- ---1441-----32333526334777433233334344344444343333423534233332322221-22121222-222222223223433335233333476813-326834223322343453534R316552233634542443332263232413411111---62221----------1-1-4----2335- * d.332 RGC domain-like
[ 754] -------------------------11---------1-----------------111-1--1------ ---------------------------------------------------------------------------11---------------------------1--------------------------------------------------------1------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------11--------1--------------------------------------------------------------------------------------------1----------------------------------------------------------------------------1----------------------------------1----------------------------------1---------------------------------1---11-1-------------------------------------------44------------------------------------21----------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------1------------------ 21---2--1-1---1322-2333333211112122-1111211122212122111111-1112-3211121-212----11221311--21121321111111322-11-13345G846445518E5I5RoB2E8G44347478637244645C23566--124214121--121111-4---1-5112142----2-- * d.103 CytB endotoxin-like
[ 755] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111-1--------------------------------------------------------------------- -----------------------1--------------------------------1-----------------------------------------------------9JKDCEA7886774GB6B6KbD-A7G5876D45B848545975E7G8794EM43435833D6864-1---------------------- * d.164 SMAD MH1 domain
[ 756] ---------------------------------------------111-------1------------ -----1-----1----------------------------------11-11-21-11-11--1-------1-----------2----------1------------------------------11111111211--------1-1----------------------1--------------------1--133323-232333-14-222-3333121--2-11111--1-11111111111111111-1-------------------1------------------------------------------------------11111111-1---111212-1--------1------------------1111-------1---1--1--1---------------1----11---------1--21-11-----1----1-1--------------2--------------------------------111-121232--2-23222222212222221112522112231121-212131--11--111-------11-122-1--2-1------1-------1--122122----------1-----------1---111----1-----2--111---111-1-11---1-----111-11121221312222222222-22222222222222222221211111122222222222323221122222211111111111111111-11111------111---111---------11111--21211-1--23-2211112211-11111111----111111111221111111---1111-------------------------1----1---1-1-----1-----1--------21- -211111-----11--2--1---121111-------1211-12---11---------1-----------------11------------1--2-------11------21--------1---11---1---------------------1----1----1111-----------------------113--1----1-- * b.75 Bacteriochlorophyll A protein
[ 757] ---1-------------------1211-12-------1----1-Y-14-1B-1-11------1----- ------------------------------------------------------------------------------------------2---------1--11-----------------------------------------------11-----------6--1-------------112----1--------111-21-1-1-------2-----2---------7--------------------1---1----------11--------------------------------------------------------9-----------*----562--*---11----B----------------G-----------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------G------------123--2471------1-2-------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1--------------------------1--1-------1- ------3-5211-----11-1-1---------------------------11-1----------------------1--1--------------1----------2-1719342252212-133412318D3-523123131534243-152-3263122232211--142--21-1224---1-2443-5-2-44342 * a.139 Type I dockerin domain
[ 758] ----------11-------1----122---1--1-----------------1---------------- -2----------------------1-------------------1---------------1------11-----------1-1-------1-------------1------------------------------1---------1---1--------1----1--1-1--------------------------------------------1---2----1------------------------------------------------1----------------------------------------1----------------------1---11--------1-------1----------------------------------1-----------------1-11------------1-----1-------------1---------1-1----------11-----------------------------------------------------------1-----------1------------1-11----------------------------1--1--------3---------------------------------1---1---------------------------------------1--------1-----------------------------------------1-----------------------------------1-1-------------1----------------1--1111-------------------------------------------------------------------------------1----------------------------1-- 2111233-3221333224223232222232222342233333322244533433232433332232222222224322342222322222222427323235222222415344232211123243151RK4-722-11121121112--42142231113-12222322112612111D22-1121552311131121 * a.268 PTPA-like
[ 759] ----------------11------2----3-------------------------------------- 21--2----------1111-1---1-111111------1----42---11--111---------1-21---1111-11----------1111-1------4---1---1--------------------------12211------------------------------------------------------------------------------------1------2---------------1------1------------------11---------------------------------------------------2------------------2----------------------1------211-------------------------------------------4--1221111----------1-11------------------------------------------------------------1111---111-----111111-----------1---------4-----------------1------------------------------1-------------------------------------12---1------1--------1--1--------------1--------------------------------------11------------------------------111111-1111-----------------1----------------------------------11---1-323----------------------11--12-22----------1----------------1-------------------------2----------3-- ------3------1-7BA7A985C8CC1222221211222212111A45DEFJHDEA555651-1-1-----2-3---1------1---526B4711251124--4--3--------------------221--------------------------1----1-1-------------------313A64-111-132 * b.133 Dextranase, N-terminal domain
[ 760] -------------------------------------------------------------------- ---------------------------------------------------------1-------------------------------------------------------------------------------------1-11111111111------11111111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11----1---------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122115---1--1--1-11-1111-1--1131-1--22--1-------1--2--1--5-----1-----1------1------------1-1412-----1-----43-B114-4B25CH3-734A38DI3-42566B7151-45-85738626434455664445---14-B3-GG-7---4-4jEd26D--13141 * a.280 RbcX-like
[ 761] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------3332-21----32-----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------1---------------------------------------112213--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------B-------------------------------------------------------- ------------4-8-----------------1----------1--1E-1---31--7-----54----4-------------4-----Q-2--11---4-7J-----11-1111-------------------------------------1---------21-49---1-----11----41-1MA2-4---3L**- * d.98 BLIP-like
[ 762] ---------------1-------------21------------------------------1----1- --1--------------------------------------------------------------------------------11111---------------------------------------1------1--------1-1111111111111111111121111111111111111---11----1-1111111111111111-11--111---1---------111------------------------------------------------------------------------------------------------------------------------1-11---------------1--1111-1--1111111111111111111111111111111111121-111111111111111111111111111222222221111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111---------------1-1-111----------1111111111111111111111-112211-111111111111111111111111111---1111------1-------------------------------------------------------------------------------------1-----1111111------------------------1111111111111111111------------11111111111111111111111111111111--------------------------------------------------------- -3------2------1--1--------1-------1--1-1---1--11-----111-1---11111-1-1-2---1----------11----1---11------1------11111-----1-11-1-13--11-----1--21--------1-1-------1-112--s-1--2-21K11111-118-11------1 * f.32 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
[ 763] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----1---1-----------------------------------------1-----1----------------------------------------------------------------1-1--1----------------1-1-----------1-------1-------------------Y***-*M---1--- * b.143 NAC domain
[ 764] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1--------------------------------------------------------1----------------------------------------11---------1--------------------------1------------1-------------------------------------------------------------------------------------1-1---------------------1--------------------------------------------------------------------------------------------------------------- ---1351-33213332332322313-12323332333424444322123433333332323323333333333213313332332233322333452223122231232264533343322233331436B3-4452323413342343233352133311223333444-43432332B3-1333244233323333- * d.344 GINS/PriA/YqbF domain
[ 765] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------2243-111----21--1-------------------------------------1-------------------1----------------------------------------------1-------------1-------------------------------------------------------------------------------------------------------------------11------------------------11-------1----------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------1------------------------------------------------1----------------------------1------------------------------------------------------1--------1------------------------------------------------------1--------------------------------------1-------------------1-----1----1------------------------------------------------------------------------------------------------- 1111--3-1--12112311112111112222221111111111222-111111311112111111111-1-1111------11111---25232231111211222-2R1H666676343244385374CM6-757233153435243214229234457744942232414643222121-122276A1723212113 * a.224 Glycolipid transfer protein, GLTP
[ 766] -------------------------------------------------------------------- ---11-------11-11----1111------11---1----1111---1------1--111111-1--1111111111111111--11-----------------------------------111--1--11-1-----111-1-1--11-----------1-1---1--1-----1----11-----1-111111111111111111111111111111111-----1111111111-111111111111111-11--11111---1111111111--------------------------------------------11111-------1-1-1111111--1-1-1111111111--11---1-1111----------------------------------------------------------------------------------------1----------------------1--1-1--1-----11111111111111111111-111111111111111111111111111111111-11111111111-111111--11111111111111-------1------------------1--1---1-11--111111-11-1-111111111111111111-11-11-111111111111-111111111-11-111111111111111111111111111111111111111111-1111111111111-1111111111--1111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111--------11111111-11-11111111-1111111--1111-111111- 1-------1---------------------------------------------------------------------------------------------------1-2----------------------------------------------------1------------121F111---------------3 * a.108 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
[ 767] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11--221-312-22212224333243222221233322221222222222222222322222211111-11111111-111-111122235322233323233221-22234333464334444774B5BR528595333634434453364453533331123333534425341322E2222242342211222221 * d.232 Mago nashi protein
[ 768] ---------------1-------1-11---------------------1---1---------1----- --1-2--1----11-11----1111------11111--1-111-1-11-11113-1--11--11--1-1112----11-------1----11--1----1111-111111-------------1-------------------1-1-1-----111--------------------------1----1-----1111111321411111----1111112111121123212111112212133111212122-1-1------3411----1---11121121111111111112211114331111211211121111111----11211111131-143111122-1--111---1111--1-111-----11---1----------1-1-------------------1---------2------111---1-------------------------------1-----------------------------11-----1---1-1-------1----1---11--------11--11--1--1---------------------11--------------1-1---21-----2-11--1---2-------------------------------------1-------------------------1------------------------------------------1----------------------------------------------------------------------------------------------1------------------------------11111111111111-------------1-112-1-----2----1--1-1-1--1-1----------------- 21------1---1111-2211212111---------11211111111112--1-11112111-1-1111111--11----1--1111-1121-1111111111-1---1-12121-331-212-24223491-13211-11221-11-2-2221211-111211-21---21211--11B111--41221-2122-1-1 * b.172 YopX-like
[ 769] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111111111111--111111111111111-111111111111111111-1111111111111111111-11111111-11-111111111111111111111111111111111--11-----------------------------------11----11---1------11-1-11111111111-111-----------------------------------------------------------11111111111111111111111111-111--1111-------1111111111111111--11111111111111111111111111111111111111111111111111111111111111111--111111111-11111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111--1--------------------------------------------------------- ----111-211-11--1-1111111-11111111111111111-111111111111111111-11111-111111-1111111111111121111121121-1111-1--223121221111112211-151-1151111321111221-12121211122112111211--1111111---11112-1-111111112 * a.218 YgfY-like
[ 770] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----11--1---111----2121232--122-1----3222121221---------112-11111111-122111-1-1-1-111111---------------21111--3887C974454444AC595Og71C8C45238554445645844F475442114224-22142C12---11-111-162F2C4223696- * a.12 Kix domain of CBP (creb binding protein)
[ 771] -------------------------------------------------------------------- ------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------38687G356374G8YI3B9uxI-KEIA644824A7464-775334C57C32--432A4662112------------------------- * g.1 Insulin-like
[ 772] -------------------------------------------------------------------- ----1-----------------------------------------------------------1---1-------------------11----------1---31-------------------------------------1-1--------------------1121----1-------1-2-------------1------11-------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------1-2112-----------------1------1-323--133721154-3--1---31-222212---------2-2-----------------------1------------1--1--------------------------1---11----------------------------------------1----------------2----2----31----1------------------------------------------------1--------2----------------1221111112--11111112-112121222--------------------------1---11-----------------------------3------------------------------------1------1--------------------------1---------------1----166-------------------------------------------------- ----554---1-1121211122222221112221222212122111-1111113111111111--------------------------12-212-----1--1-1-5327333341133233243243BO6-335233233452241333413452332233441132125547----------3325134--5336- * d.297 WGR domain-like
[ 773] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------- 4311112-K87222211-1111111-11111111111111111111-1111121111111111-1111--1--11-1---1-11--111111111111111-11121142D465463-244332772338F5-4372335423742324333342543344322822723C36221333X11123577H1641266748 * d.39 DLC
[ 774] 111211111111111112222221-11-111-111111111111111111111111111111111111 11-------------------------------------------1-------------------------------1--11-11111----------------------------------------------------1111-1------11---------------------------------11---------------------------------1---------------------------------------------------------------------------------------------------11-21------------11------1-----11111111211211111---1---------------------------------------------------------------------------------------1-1------------------------------------11-------------------------------------------1----11---------------111-111-111111111-11111111111111-12--------------------1-11111--1-------1-------1----1-1--11-----11--------------------------------------------------------------------------------------------------11111-1-----------------------------11-1--------------------------1--------------------------1---------------1---------------------------1111111111-1-- 11--111-311221211111111111211111112111-1-11111112111213122211122222321112-2112311222223221-211211112111211-16142222122243222332437A4-336323222322222332323223221121111131151112111-6---1-222321111-112- * d.309 AMMECR1-like
[ 775] -------22222-22-11--------------------------------------11----1----- --1----------------------1-----------2---------2-2----1-------2---3-------------2---1-1----11---------1------------------------------1----------11------------------------1----------------------22222122122211222----221---2---11111-----------------------1----1---------11----------------------------------------------11--------31----11-----1--1----11-1--2--11-3---12122---------11112111--212--11111111111111111--------252--3333221322111-221--2------111111111-11---2------------------------------11-3-------2333222222233523332324421--1-----21-----11--21--1111-11111111--111----1----11---1-------------12-----------------------------11----2-1--------------------1-----------------------------------------------------11---------------------------2---------------1--------------1--------11----11-1111-1--1--------11-----1---------------1----------11-1111111-111------11--1111111-----------------------------1-1--12111---- ---111----1--1-13521--13222113223242323332322213132353211--111--121-----111--------------1113-1-1-1------1---271---111--1---5-1--141-11--1---1-21------------11-----11-----1111--------11---21----2--2- * e.73 CV3147-like
[ 776] -----------------1------------1---------------------------------1--- 1-1---1------------------1-----------1-2----3-1---1-232--------11-2---1-----------1-----------------------1-2------------------------------11---1-111111111111111111111111111111111111-----1--------------------32112------1-3---------1-------------------------------------------------------------------------------------------11--11-1121-1--1--1--------1-11---1-1---11-1--11---2-11------1-311---121--12221221221---2-16-2-1--411-3364333333---1111-121-1--------3------1--------------------------------1--121123221212111-22231111-11-31133-112----1-313221---1-----1111112-----11------2-1------------------1----------------------------111-1-------------------------------1-1--------21--11--2122211--111-211-1-2-11111-4432311-3-2222221221212211-----1--111111111111---------------132---3-3--1-21221-----------------111--11--121----------1-1------1---------------------------------------------------------------------------1-- ---------------211-21112121-------1------------1--22222211------1-------1----------------11-1-1-1--------1-1111-11---------12--11-31-112-1----2-3-21-1--1--231122--1-213--1-1----111---1-1341-12-1---12 * c.146 YgbK-like
[ 777] --------------------12-------------------------1-1-11-----1--------- -----1-1111--------------------------1--------------1----1--1--------------------------------------------------------------1--1-1---1-1---------------11--------------------------------------------------1----------1-1-1--------------1-----------------------------------------11------------1----------------1---------111----1-------1121---------------------1------1----1-------111211111111111111121111121211111-1111111111211111111111111111121111111111111111111111111----------121111111111111-----11-1112221111111111111111111111111111111111111111111111111211111111111111111-------------1--------1-11-1-1-1--1--------1-1111--1----1121221111111111111111111111111111-11111------13111111111111111-1111111111111111111211211111111111111111111211111111-1111111111111111-----11111111-121111111112111111111111111111111111111121111111111111112-212211111111111111111111--11------------------------1---------------------1--------- -1---1----------1--1--11-1--1-----------------------------------------1---------------------11--------------1-------1--1----------1-----11---1---111-1-1--1-------11-21---31-11-------1--1--3-1---1122- * c.128 DNA polymerase III chi subunit
[ 778] ----------------------------------------------------------------1--- --114---------1---------11-----1----11-1------------1-2--------------1-------------------------------------------------------------1-------------------1-----------1------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------244-42---------------------2------------------1----1-------------1-------------------1---------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4------11---1-------------------------1----------------------------------------------------------------------- ----52-----------------2-3-1---------111111-----1-3152-----1-1--------------------------------1------------115--3811-------------------------------------------------2-----------1------25*X*-V*-1----- * b.78 beta-Prism II
[ 779] -----2--------1-1------1----------1--------1------21211111111---1--- ---------------------------------1-1----------1-----------------------------------1----------------1-------------------1111------------------------------------------------------------------1--1---------1--1----------1-----------------------------------------------------------------------------------------------------------------------------------------------1--------1---1-111111111111111111111111111111111-11111111111-11111111111111---1111111111-------------1-111-11111-----------------1111---1--111111111111-11111111111111111111111111111112111211212111111111112111211--1-1---------------------------1-----------------------11-------1--------------1----------1111-------------------------------------------------11-----------------------------------------1111111111-------------------------------------------------1111111111-------1------1211111111111111---------------------------------------------------------- ----11--211-1-11-1-11111111111111111111111111122111-1211111112211-1--1--111--1---11111----31-2111111111111-13-6322212113122244252A86-534222332222221122212222232--11111111-132111112111-112141331111121 * c.103 MTH938-like
[ 780] ----1----------------1------1------------------1121----------------- --1--------------------------------------------------1-1------------1------------------------------------------------------------------111-2--------------------------------------------1------------------------1-----------------------------------------------------------------------------------------------------------------------------------1--------------------------------11111-----1111132112111--11-111111111111111411-111111111111111111111111111------------111-111111111111111111111111-111111111------111211111111111111111111111111111111111111111111-1111-------111111-------------------1------------------------------------------111111111111111111111111111---11-1--------------------------------------------------------------------------------------------1-----111111----------------------------1111111111111111111-------------1-----111111111111111----11------1---------1----------------------------------11----- 11--121-311-1111111113111111112111111111111111122211111111121212211111112121111112222211211111111211111111-11-1331121111111132-112C2-24211-12-112-1111111111211--112111111212111111A1111131-22121111211 * b.146 Ctag/Cox11
[ 781] ------------------------------------------------------1-1111-------- --1------------11---------------------------1---------------------------------1---1-----------------------------------------1--------11--------2--------------------------------------22211111112111111111111111212222111111122222222221222222222222222211221-1-22-------22121-----1113332111211222222222221111111111111222111222211222111111121212--22211111111111111111111111111111--------------1-------------------1-11211211111-111111111122-----1113111111--------------11-------------------------------------------------------------------------------------------1-----------1--------1---------------1-1111---------------1-1111111-------111---11-111111111111111111111-------11-111111111-1111111111-1111111111111111111111111111111111111111111111111111-111111111112---------1111--2-----1---------------------1-11111111111111111111111111-11111111111111----------------2---------------2-2------11-1---1111---11----2--111111---- -----------------------1----------------------------1---1-1111----------------------------------------------------------1------------------------------------------1----------------------------------- * d.327 DeoB insert domain-like
[ 782] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1111111----------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----221-----2222132222322221122222211222222212222212223222233322322222221222222221222212223212311111222213122213433452343433A5342HM6-A572344324424431332371444513372122423J331211-2C211224323262------- * a.32 Transcription factor IIA (TFIIA), alpha-helical domain
[ 783] --------------------------------------------------11---------------- --------------------------------------------------------------------------------------------------------1----------------------------1-------------1---------------------1-----------------12------------------------1-----------------------------------------------------11--1--1-------------------------------------------------------------------11----------------------------------------------------------------------------------------1------------------------11----1-------------------------------------------------------------------------------1----------1-----------------------------------1---------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------1----------------------------------------------1---------------------------------------------------------------------------------------------------- 11-1332-11--1221122535312352222222223222232222313322232241242332221112132121111122222323211-1321112111122312224344334343354-24344AH5-45815444253543253343533543--232-21-1221122112-8-1---55943A3-13116- * b.91 E2 regulatory, transactivation domain
[ 784] ---1--11-111--22-11111121--11111222222222222233222222211-----1--1-1- -111111111111111111-111111111111111112111111-11-1111221111111-2121112112111222-113111111--1--1----------1--1----------------111111111111111111111111111111--111-11-11-11111-11111-11111111111--1122223222122222211111122211111--111111--111111111111111211111--------------------1-111-------11111111111111-------------111111111-121111111111-1-14221---1-1-321111111111112111121-1-11---11------1------1--1----------------------------------------11------1----------------------------------------------1--1--1--------------------------------------------------1---------------1---------1112-1111-----1-1-11111-1-2-1--1--1--------------2-1-----------------------------------1---------------------------------------------1---------------------------------------------------------------1---------------------------------------------------------1------------11111111-----111111111--------1-1---------------------------1--1-111111- -----------------------1-1111----1-1---------------1-11----------------------------------121--1----------1--1--42211-1----1---1--171-111-1-1----------11-----------1----------1------1---1------------- * c.127 F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)
[ 785] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------1----------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111111-111111-1111-111111-------1------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ -1------1---------2------------------------------------------1----------------------------------------1-------2---21--------2-21---------------1------------------1----------11-1--------S***1*K12----- * a.52 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
[ 786] 11--11111111111111111---1--11111-----------------1----11111111111-11 111-------------------------------------------------------------------------------11-1------1--------1--2--1---------------1-----------11111---11--1------------------1111------------11-111------------------------1--------------------------------------------------------------------------------------------------------------1---------------------1-----2------------------1-1-1---------211111111111111111111112-32123221211-32222132113311---1111111212222222222---1211-------------------------------1--------------------------------3232-1222221111111111111---3--------111111-111---1-11111-1-1------1111-111------------------------------1--1-1-------------------------111--------------------------------------------11---1--1-----------------------------------------------------1----------1----------------11111111111121----------------1111-1--111--------1--------1111-11------------------------------------1111111111---- --11--1-1--1----1-----1-2-1--------------------2--111---111111---------------------1111-----11------11---1----222112311113213-171CG2-536114122222121222--32223311-1512152233431-1---------1--13-111---1 * c.118 GckA/TtuD-like
[ 787] 1111211111111111111111111111111111111111111211111111111111111---1111 ---------------------------------------------------------------------------------------------------------------------------------------------------1--------------------1----------------------1-------------1-1----------1--------------------------------------------------------------------------------------------------------1---------------11------------1-22-1---112----------1----------2---------------------------------------------------------------------------1----1------------------------------------------------------------------------------------------------------1-----1-----------------1111-------------------------------------------1111-1--111----1---------------------------------------------------------------------1---------------------------------------------------------------------------------1----------------------------------1-1--------------------------------------------------------1------------ 2112--2-522211221211111111-11111112212222211111112122111131111111111-111111111111111211111311121111114-111124322223242122222432628I3-5342221322231123222231122113111111121321214222Q22222355213632-1-12 * e.12 DNA topoisomerase IV, alpha subunit
[ 788] ------1--------1--------1---1--1----------------------------------1- ----1--1111-111--11-12--1211111111111211-1111-1-----11111-------1-3223-----1----------------1-------1---11-------------------------------------111-11--1-1--1111-1111-111111-11111-1-1--1-------1------1---------1---1----1-1----------1-11111111111111111-1---------------------------------------------------------------111---------------------------1-11---------1---------1---------------11133---1111122222222222-3413313211--111111111111111--111111111111111111----1------------------1--------------------111-1111111111111211111111111111-1111111--111111-12-1-1-1---------1-11---------------1----------11-1--1----------211111111----1----1111---11-------1-------1-11---11-1------1---11--12--------1---------1--------111--111--------------------------1111111-111111------------1111111----1111----1111111-2-1-11111111111111212-----------11---------------------------1----------------------------------------111-----------1-- -------------1111111121111111111111111111111221111211211111111------------------------11112111211111121221--2-1----------------------------------------------------11--------2-----8111--1-121111111112 * d.8 Urease, gamma-subunit
[ 789] -------------------------------------------------------1------------ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------1-------------------------------------9DFAF957555687FB676VzE-C8G3656B579736454854A76776-462353-12151131------------------------ * d.200 Integrin beta tail domain
[ 790] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1-11221231--223222222222222222222222222222222222222222222223332222222222122222222122222332222231222222222321111333347223333274142EJ5-83722333233333-133235344341-1922215233331222-2F222324323261------- * b.56 Transcription factor IIA (TFIIA), beta-barrel domain
[ 791] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------------1-1-11-11-----------------------------------------------1----------------3441234-414775H5393LYC-85B431363545344526114232321-3276E69-2Ar*1------------------------- * d.6 Prion-like
[ 792] -----------------------1-------------------54-4B-1966--1-11---1----- --8-1----------11------------------------1----------1-------1---------------------1-1---------------------1-------------------1--2--7-----24---113B58JIP--11------161-554-----1----------23---1--11111---1-----------------------------------------------------1--1-------------------1-------11----------------------------------32----------1----43-----1--2--2-4234275---4---5----31-11--11-21--1-1--13-63------------21-1113--1-----1-11--1-2-1--1---1-2--1----------11----1------------------------------1-21---21-1------------1-11---1--12-11-----------1-------1-----12-----1----1-2111----2-211-1-11--312--1-------1----211----1-1-5--------------1---------------1----1-----91-3------1-1----111-1------1-1-1--1-11-2--1----1--1441----------------1--1---1--122212212211---------1--------------------21---11-1----1---1-3-12--------------------------------------------------1--11----------6-----------------------------2---------1- ------1---------1---------------------------------------------------------------------------1--------------------1-------1---------------------1--------------------------1------1----2-----1---------- * d.304 TTHA1013/TTHA0281-like
[ 793] --------------1-------12-------------------15--1--31-----------1---- --2-1---------2------4--31-----222222522-112-1--------------1---------------------------------------2----1------------------------------11-----1-1111--1---1--4-5----------2-----5------1---------------------------------------2223231-----------------------------------------------------------------------------------------------------------------------------------------------11111-1212514125112121211111111112-21433311-55-21121228416A25-11-------1----------1--------------------------------------42--153-21111111122211612221112217A49--111-----3----1-32-------------------2-2-1-1--3------------------1---------------------------1--------5------1----21--1-12-12----------------------------------------------------------1----------------------------------------------------1---------------------1--1---1-----1612216112-11---------1177------132-1-----------------------------------------------------------------------1-- ------1---------2122-1131321-12121---------------11-----2-1--2------1----1------------------2--1-------1-1--4-11---11------12---------------------------------1---11---1-1----2-5---1----1--4111-1-2--- * e.65 VPA0735-like
[ 794] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------2222211111----------------------------------------------------------------------------------111111111111111111111111111111222------1112222222222222211122---------------------------------------------------------------------------------------------------------------------------111211111111111121111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111----------------------------------------------1------------------111---2---------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2 ----111-211-1111111111111-11111111111111-111111111111111111111122111121122211-11122222-1111111111111111112-1212363242111111131111372-11-1-111111-1111111111111121121111411111111111I1121111121211121111 * d.267 Hypothetical protein SAV1430
[ 795] -------------------------------------------------------------------- ----------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 11-1112-522113211111111111111-11111111111111221111111-11111111111111-1211111111111-11112114211131111121112115233332263231443883C4Gc8-94A32327444334313434537632335I22112142122212121111-122361511111113 * d.245 NSFL1 (p97 ATPase) cofactor p47, SEP domain
[ 796] 11----1--------1------1-------111---1111111-----112----11---------1- --1----------1----------1---------1-1--1----------------------------1------1------------22----1----1------------------------------1--------1----------1---11-1----1---1--2--------------1----1----------1---------11-------11---------------------------------------------------------------------------------------1------1-------------------------------1-----1------1------1------------1-----1------2----------------------1----1---11-111-----------------------------------------1-11--23---1--------1-------111------1----------------1----1----3--------1-------------------1-----------1-----------------1--111---1---------------------1-----1--1----1---------------------------------------11--1-13--11---211-3111---1---------1------------------1--------11--1111----------------------------------1---1--------1-------1----------------------1-------------------1--------12-----------------------------2-----1---1-------------1 42-2231-3112211-14-313-1--1--1111-2--111111111212222742213-221232111-23212123314-23211111-211--1212113-212--1122-32112223222331-2191-1231131322313111234332421334-1424212-11641---111112--355-1-213221- * e.58 Viral ssDNA binding protein
[ 797] ------1122222221--1-1-1111111-1111111111111111111---11-------121--11 ---11-------------------------------11-1-211----------------11112-1113-1---------11-----11-1-111--------11------------------11-1-----1111111-----21111113211111111-111221111111111111111111----1----------------1111-----11111--2222221----------------------------------11---1-------111----111------------------------2111111111-211111111111112111122211--1-111111111--1111---111----------1-11111---1-11111221222222-2111-1---1--11111111111111--11--1-1-11-11111111----11-2---------------------------------1------12221111111--1111111121---------1-21---11-1--11----1------------11-12-1-11111111-111111111-----1-------------------------------1----------21-11----------1------1-------1---1--------------------------------111--11-1111111111111111----------1--------------------------1-1---------------------------1111222112121-121---------------------1------------------1---1111--------1------------------------------11--------1 -----------------1-----1-----1----1-------------------1--------------------------------1-----------1---------3--1-1--1-1---126--1-----------------1-----111-1111---4--------11-----------1--1----2----1 * c.151 CobE/GbiG C-terminal domain-like
[ 798] 11111111111111111111111111111111111111111111111111111111-11111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11-1111142211111111111111-11111111111111111111111-11111111-111111111-11-11112-21111111211121111211111113331121211111-1---1119U-O2Dm9-28O12119-124-11--2-111121111111111311112111111F1111152231311111111 * d.29 Ribosomal protein L31e
[ 799] -------------------------------------------------------------------- ------------------------------------------11------------------1-1----1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111------------------1111--1-1111---------------------------------------------------------------------------1----1---1-----------------------------1-------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------ ----1-1-1-11--2--2------1---1-----1--424412---------1-3--12211---1---1---------------------2-111-------11--21-G13313B7117254694A5Q*D5I9F4734926A54C353834D24522-1--1112-1-------2-11--1---3-1-1-1---1-- * d.84 Subtilisin inhibitor
[ 800] -------------------------------------------------------------------- ----1111111111-1111-111111111111111111111-111111-1-11-1111--111--1-1111--------11----1-------------------------------------------------1111111111211111111111111111-11111111111111-11-1111111-111111111111111111111111111111111111111111-111111111111-1111111111111111111221111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111-11---211111111111111111111111111111111-11111112111-1111111111111111111111111111111111111111111------------------------------11111----------------------------------------------------------------------------11-1--111-111111111111111--11-1-1111111111111111-1-1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------111111-111111111-11--1-111-------------- ----------1----------------------------------------------1--------1----------------------------1------1-11-------------------------------------------------------1-------------1--1-221---------------- * d.192 YlxR-like
[ 801] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------1-----------------------------JBBA9GA444667489679FZA-88D17436389638352751D789892322A846746F--63------------------------ * a.273 Orange domain-like
[ 802] ---------------1---------------------------------------------------- -1---------------12-1-----11111-----1---1-----------------------------1-------------------------------------------------------------------11-------------------------------1--------------------1-----------------11-------------------1------------------------------------1--------------------------------------------------------11----------------------------------------------------------------------------------1-----------1----------------------------------------1-----------------------------------------------------------------------1-----------1-----------------------1------------1---1------------------1-------------------------------------------------------------------------------------------------------11-----------------------------------------------------1--1--------------------------------------------------------------------------11111------------------------------------------------------------------- ------2-----11--2---12-1111112111-1-111111111111211221--2112-1---1----------1-----------1-1-2--15331-1---1--1-554456434425G575486CW617682253432h563762745A543C4132123441111--2--1----------------1----- * a.73 Retrovirus capsid protein, N-terminal core domain
[ 803] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111--11--1-----------------------------------------------------------------------------------------1-----------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 11-1422-A54-34311121111121111111111111111111112112111111112211111111-111111111111111111111211311111111213212132121121114412121-212D3-12213493111-11E461113-1111121111--E143HK121111E111238E7D2K43443331 * a.157 Skp1 dimerisation domain-like
[ 804] --------------------1----------------------------------------------- ---------------------------------------1-1----------------------1-----------------------------------------------------------11--------------------1-----------1-------------------------------------------------------------------------------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------------------------------------------------21222222---1--------------------------------------------1-------------------------------2------------1-------------------------1------1----------------1------------------1-------------------------------------1-------------------------------------------------------------1----------------------------1-----1----------------------1--------------------1--------------------------------------1------------------------------------------------------------------------------ --11122-1-1-2223211132322321132332213323233222223431331111121211111121111121111111111122212123122221-11312113145323362232322892415B3-3242323224632213233372453316412211334223211--141111121232312-11111 * d.379 Taf5 N-terminal domain-like
[ 805] ------------------12111---------4242423333222442222222-------------- --1-2---------------------------1---1------21-------------------212--21-------------------------------1---1-----------------------11-------1---1---------------------------------------------------------1------1-------------A-------------------------11-------------------------------------------------------------------------1---------------------------1---------------------------1--------1--1-------------------------1------------------------1------------------2-------------------------------------1--------------------------1-----1-----1----1---------1-----------------2--------------------------------------------------------------------2------1-1----1------------------------------------------------------------1------------------------------------------1-------------1-------------------------------------------------------------------------------------------------------------------------------1-------------- --1-32-----111--131---1----12--2-----1--1---2-11------1-111121--1----1--1---2121---111-1----11-1-----11--4---66333257447222374492BZ4-646242536-2142437365512521432412211115321---1-------1--1221--1--1- * a.89 Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
[ 806] 1111111111111111-211111-111--1------------------------11111121211111 -1-1121111111111111-1111121111111111-1111111-----11-------1111--1111111--------111121111---------------------2222222111111111111111111111111111111------111111111111121111111111121111-1-11111---11111--2---------------1---------------1-----------------------------------------------------11----------------------------------1111-1111111-1--1221111-1-11-2-11112221111111111--11----------1---------------------------------------------1--2----111------11111111111111--1112111111111111111111111111111----------------1--------111-1--------------------------------------------1---1-111111111111111111121111-2311111111111111111111111-1111----------------1--------1--1-----------------1------------------------------------------------------------------------------------------------1----------------------------------------------------------------1-----1-------------1-1111111112--2-11------------------11------1112112111---- --1111------------1--11---------------------------------1-------------1----1---1-------------------------------------------------15---------1---2---------1---1------------------3----11-1--1---------- * d.207 Thymidylate synthase-complementing protein Thy1
[ 807] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------ 1112211-733-1211121211122221--111222121222211111111111112111111312211112222111111112121111-11--111111---11-131244234521332526613-7a5-5583244434531422232393223131312211422311211212J111-245A616221234-2 * a.189 XPC-binding domain
[ 808] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------------------------------------1------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------1------------------------1---------11------------------------------------------------------6999C986574655F84D6SiC-B5E45556668346535834A5L665-112131261242121-----------------------5 * a.277 TAFH domain-like
[ 809] ----------------------------------1--------------------------------- --1-----------------------------------------------------------1------------------------1-------------------------------------211--1-211-------1---------------------------1----------1--------------------------------1------1------------------------------------------------------------------------------------------------------111---------1-1----------1-------1-----11---1----------------1------1-11122222222221--------------------------------1---------------1-----------------------------------------------------1----11---------1----1-1-----3---1-1-1-------1-----------1------------------1----1-------------------------------------12-111111111111111211111111111--1-111------22111222222222222-2222222222222222222222111112222222222232322122222221-211111111111---1-----11111232211112212211111222222232211111113222233333222111111111222221111133222-1214111111111--2-----11-------------------------------------------------- ----------1---1--1----1--1-11------------------1--1--------212----1-----------1----1-----1-----1------2----1-11----2-1------11-------3------11----------1--1---------1-------------------2--------1---- * a.199 YgfB-like
[ 810] 113334----------474553342-----34---11111111-11111-413-5564457-326--- -------------------------------------------------------------------------------122-----------------------------------------------------21121---11--1-------------------------------------43-------------------------------1------11-----------------------------------------------------------------------------------------------1321-1111111-1---11-1-1-----5--1211-2A2-54322-14---31---------------------4----------------------------------------------------------------2-1---------------------------K---------------------------------------------11-11-1-1----1----------------21--6B41572153222-596143553------64---------------------2-----------------111---1---1--1-11-----1--------111----1111111111-111211-11111111111--------1-----------------11-1-11------------------------------------------------------------------1----------------------------1-----------------------------------------------------------------11---2------- ------1-----1--------------1--------------------------1---------------------------------------------------------1--1-----------------42------------------3-1-------1-----1--------------------21--1-1-- * d.152 Aldehyde ferredoxin oxidoreductase, N-terminal domain
[ 811] ------------------------7--7-C81-----------------11----------------- ----2---------------------------------1----------11-246-------1-----------------1-------------------31-5222-2-------------------------------111--4---------------------------------------------1----------------------1--1----------------------------------2-----------1-------------------------------------------------------------11111111-1---11----------------------------------111-11111-------1-----1-11111-11--1121141111--1221111111--------1------2-----------------------------------------------1111-13333-22222-------------------------1-21111213311-2---2-----12111--2-11--21--2------------------------2-------------------------------21------2------22---2-2----------------1---2--2332222222-3222222222322222222----222-----------------222-2232--222222222222---4--------------111222---112-122222222---1233331441111112111------------------------11111111111111----11------------1--------------------------------------1-- ----------------------------------------------------------------------------------------------------------------------1-1------11251-11---1-----------------1-------------------------------------1---- * d.348 YegP-like
[ 812] -------------------------------------------------------------------- -1----1----1-11-------1111-----1-111---------------111----11-------111-------------11--111------------------------------------------------------11111111111111-----12111-1-1-----1-------------------------------------------------------------------------------------------------------------------------------------------------11----------------------1-----1111-11-1---111--------11--11-1--1111----1111111111111-----------1---11111-111--1-1-------------------------111-----------------------------------1---111111122222221122221222122221211121---11-211111111-1-1121111111-12----1------------------------------------------------------1111111111111111--1111111111-11--111111111111111111111111111-1111111111111111111111111111111111111-11111111111-11111111111111111111111111111111111111111111111111111111111122121111111111111----------111211111111111111111111111111---------------------------------------------------------- ----------------------------------------------------------------1----------------------------------------------------1--1-----111372-113----1-12311---1--------------1--------1----------1-----------1- * d.229 MesJ substrate recognition domain-like
[ 813] -------------------------------------------------------------------- ------------------------------------------------------------------------------------1-11-----------------------------------------------111-1---11111111111111111111-111111111111111111---1111--------------------------------------------------------------------------------------------------------------------------------------11-1111111111111--11111-1--1111111111211-1111----------------11111-------111111111111-1121121111--111111111111-------1-------1111111111111-1---------------------------------1--111111111111111111111111111111111--111111111111111111---11111111111-111--1-1-1----------------------111-----------111111111-1---1211111-1-11111111111111111111111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111------11-111111---------------1111111111111111111111111111111111111111111111111111111111111111111------------------------------------------------------------ -----1-------------------------------------------------------------------------------------------------1--------------------------1----------------------------------------1--------------------------- * d.71 Cell division protein MinE topological specificity domain
[ 814] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------1-1-----------------------1---------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ------6---3------1----------------------------------------1------------------------------------------------13-K7J7EA8334334353344Nc7-4462434A33523423442266554488E-2712974337H---------1---1----1133331 * a.83 Guanido kinase N-terminal domain
[ 815] 11-31111111111112112111-4222223211111111111-----1----1---1-11---2-11 -11-----------11111-11--1211111122221121-2-1--------2-------1-----112-------11--1-3--1--11-1-----------11-1----------------------------111------112212221122222222-21-22121221111211212----11--------------------1-------1----1-111211-1---------------------------------------------------------------------------------------------------11--2-----111111--------111----1-1--1----4--111111111211121111111111111111112-33233231432131132212221111-11212----11-111111111--11-22------------------------------------11--111--2--------2------12--11--------111122134------1-2------------1---------------111111111-----1-1-1-------------------------------------------------------------1-------------------------------------------111---1-------------------------------------------------------1----------------------------------11----11------------1---------------------------------------------------------------------------------111---- -----------------------------1-11-----------------------1-------------1-------1---------------1-------------5------1------1---1-------------------1-----------1----------1-------11H---1----1---------- * c.125 Creatininase
[ 816] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----------------1--------------------------------------------------------------------1------1------------------1-2-3466599E5JG7GAWVJ-GD8G988715D497H57957D35181----1----------------------------------- * d.5 RNase A-like
[ 817] --11---111111111-1--111-1--1-111---111----11---2---1--2111111--111-- --1-2--------------------1---------------1-11-------2-------------1111------------------11----1-1------------------------------------------2---1--1--211----------------15------------------------------1-------1-11-------------------------------------------------------------1-----------1-------------------------------------1-1------------111---------------------------------------------111---11-------------2---1--1---1--211-212112------------1---1111111111-------------------------1---------------------111111-----111--------11--------1-----1---1--1-----1-------------------1-------1-----1--------1----------------------------------------------1---------------------------1-----------------------------------------1---------------------------1---------------------1----1--------------------------------------1------1-----------11------1---------------------1--11---------------------------------------------------- 1-11112-3-212131111112231311111111-11111111111-111--1----11---1-1111--21---111121-----1111131314111--11221-122D1324241---21-42-33471-2121-1-11111122312-14-1334131123312334-132-1-1--21-122231222132123 * c.131 Peptidyl-tRNA hydrolase II
[ 818] ------111111111--111111-11121212-----------------------------111--11 -11------------------1---1------111111111-11------------------1-11-1111-----------11----1111-1---------------------------------------1-12211---2111111121111111111121111111111111111111-111----111111111121111111121111111111-11------211111111111111111---1------------------------------------------------------------------------------------------11--------1---------------------------------1-------------------------------------2------------1-------1-1-------------1-----------------------------------------------------------------------------------1-----1--------------------1----1-1-111-1121111-1--1--1------------------------111--------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------1---------------------------------------------------1---------1111------------------------------------------------1- ---1-22--------1----------1------1------------11---11---111---11----1---------1--------------------1-1-1---1714223551232223235242DJ1152512222233112331211223222--21322-2--2--34-11-1-----1213-12----2-- * a.246 Hyaluronidase domain-like
[ 819] ------1111111111--1-1-11--------1111111111111111111111-------211--11 ---1---------------------------------------1----------------11----1--1-----------11-----11-1-111--------1-------------------11--11---1211111-----11111111111111111-111111111111111111111-11--1-1-------------------------1111---1111111----------------------------------11---------------------------------------------11---------111111111111111111111111----111122112--1111----11------------1--11--------111111111-1-1-1--1--2----111--------11---1---------11111111----11-1-------------------------1-11-----------111111-11111111111111111--------1-21---11-1---1----1------------1