[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Summary of SCOP_SUPERFAMILY&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbsp&nbspGo To Summary without VIRUS
see 1-100     see 101-200   see 201-300   see 301-400   see 401-500   
see 501-600   see 601-700   see 701-800   see 801-900   see 901-1000  
see 1001-1100 see 1101-1200 see 1201-1300 see 1301-1400 see 1401-1500 
see 1501-1600 see 1601-1700 see 1701-1800 see 1801-1900 see 1901-1908 


       aadishmssssssssstcpppptahhhhhhhnmmmmmmmmmmmmmmmmmmmmmmpppttttpttkncn aasaccccccccccmmmmmmmmmmmmmmmmmmmmmmnrrrafffkbbkjcclaaakmrttssnpassssstbbbbbbbacesrahpssbbbbcpppassfcffgrccdspccccccccccccccpccccccpppcpcccrrdddhtacccccmccsssssssssstgaantppppppppppppdddttddeaabbbbbbbbbbbbbbbbbbbbbbbbbgggloeellllllbpmsssssssssssssssssssellllllllllllllllllpllolllssssssssssssssssssssssssssssssssssssssssssssaaacccccccccccccccccccccccafseehdddddpshncmtttccflgtrcccpbbbbbbmbbbnnorrrrrbbbbbbbbbbocmmmmmmmmmmpcaaaarrrrrrssaxhhmdjprrrrrssaaaaaaaaaggggmrraaaeeeeennoorrrrrrrrrrrrrwwwwpensszbbbbbbbbbbbbbbbbbbbbbbbbbbbbbcrrrpprrrlmaaddpprvvhjatmmmclnnnnnnnnnnaadbdddddddddddddlgggggggppaaaamsssacccccccccchhhhhhhhhtwnnsaaaatamscipppsssssssssssssssssssbcdnahtbbbbbbceddeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeekkkeppppssssssssssssssssssssssssswyyyyyyyyyyyybbckcccccllllmahcmaaaaamhhhhhhhhpaaaaaaapppacpppppppppppppppppffffffffftavvpvvvvvvvvvvssxxxxxxxxxxxxccmbllllllbbbbbbbbttaacopmbmmmmmmmmmmmmmmmmuuufkptttttttmoa ppccddmglltgbbsmmsaaanaaaaabbhhhhmmtuccccccpppbsttffnfvvmcsnnnycdaklslcncppssssszcccccssspphpcslccctspumprecenbogttdopleoocdmrsmghhhhppctmotcftbsvpmesedcmmgtaxccchcldbdaaaccntccvmmoooccpooppasptppppa bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
       ppkhmbsaiiiiiistpmaacinfmasmwulpsstfjammmmvbplmhtbabmkafhgkostavcesm cbufaadegggjkuaaabbbbgllmstttttuvyyyfehocarrrcfsdmmxacrrlswwatoamveacgfaaaaillpclhxaymaufftvadggammbojpfbphfrhmttttttacfppppaptclppvlptaaahcoeeearmyyyyyayyeeyyyyyyyyevnnpemmmmmmmmmmmmdgrttttmafaaaaaaccccccccccchllpsttwektsisximmmmwbacaaaaaaaaaaaaaaceehsfabbccdfghjpprrrrsspcmolllaaadeeegmmppppppppppppppppppppppppsssttttttutmoabbbbbbbbbbbcdkknppppttpmyermahhartwoththptspnbaybacczbghqtisjrrhwcpppppaacmmmmossahcdeeenprelllrttveehlllmmcabnmsadssssdipppppppppcddobmcrmmpccrrrrsttaabbccfmpprrteeopulawamabpppacccccgmmmmmmppppppptuvxteemnoppscpacianofpeaapdfmevhggmmmmmeemzzabaaoprbddmsvvvibeelmsucpddnnxcafbccfhjjjjjlahpppppppdspiuffhsamadplahiabbbbdfhhhhhlopppswcrnoehhaaaaauksdzintcccccccccccccccccccccccccccccfpppccalmeeeeeeeeeeetttttpbbdfffsgbepppppppppppfphkbbbbbppppcbcsapppsasdiiiipssmbbbbbbcacsvjaaaaefffmppppsssspttttttttcsffpccccchpsvvmmaccccoooffffmvahbbbbiiabbdghrtdplypymfpaaccfgghhhmmpppspuunomamhlmnpitm fyhpdpbtbmbiddpfgnbnffcfnotddccccgceriiiippbbbcsrvgvhoadggtcdtllhgltkegcgpsbckmpraadptjopcpaoccbnnnmrgmcbocohgflarnracatcppomntmgsssutpjsmgbfcttspvleacnhdeggctiisragpmmgambevamrcpplsthvpsstttmtpcirsa ppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppppp
       eeaoauecssssssooeaeraseualauatahmtheaeaaaaaoaaauhucaaabuoaoniocorqya aasecuiflllerrbqvooooieeamuuuuulacccaropelaaaaaeeiiyuhthuahhrrcciirvorudnnnnooaueeyedazlrrhuziiisuuacosoiiueueurrrrrrbaennnnraehihhiuhhegulashhtuoaaaaaaeeellnnnnnnnnliaauraaaaaaaaaaaaeeahhhuiclmnnnnneeeeeeeeeelaiiuuhheoahphiinooooereauuuuuuuuuuuuuuappaaacruaaeeaeolleehhaaeieeaaagggyqqqouunnnnnnnnnnnyyyyyyyyyyyyyauuhhhrrrbherceooooooooooeilloeeehehramleouaacehorhyhesearuuueaurruareurniaaaaiaaaaaabbaeeeivuunohitxxooasoaiauuittieeeeeauaeahneppppeloaaaaaaaariixeaeuaahahuuuiessfkeeaoeaeriiynnlibirilovraeemeeeeelaaaauuhhssssshrieauueeliioheviacaleairnhelotioooeeeeeuuuooralulseaeeaauuuneoooeurareeaaaecuuoueoeeeeeaceyyyyyyyeurtleeyauaqesotanmaaaaeraeeeeoneiueoiuochaipppppcoaaectaoooooooooooooooooooooooooooooennnaasuinnnnnnnnnnnyyyyyrooylllolrneeeeeeeeessleaouuuuunnnnaoharlllupuunnnnaoouaaaaaairryiaeeeenllleuuuutyyyhuuuuuuuuraiirhhhhhaapuuaaxaaaarrraaaaaegyiioonnfuuuaeeueaaehealpgraoeaeyyyoyenuyarrolofeeeaeeneu aooaiurhrarneeuiroriuillireeeaaaayaqemmmmoorrriceireaxlarlhrieiuaoahlllauataeuiaolluaracohlnsioieeeeorailruwurlacuienafeuroruoruoaaagryayuaeaaracaauuraooouauarnnaopiuoeaeerledeeauuutaluaaarrhorsanaon cgprrstkaabbbbbehhhkpppppvwbmp1plpk4arrtabbbbehppppsssvvekmpssgppppstv4bccgpp7abbbbbbbbbbbbcccccdhlllloppppppppppppppppprrssssssssssstttuvl49ddhhlnppppppssssvtbtcbbfmppxpmreep
       rrmsrtdilllllllknqrsllulrolklacaiaernorrrrnolbrnererznyrrmdnbrilyumr pcirirpfuuuioesuivvvvlpprebbbbbcnooorydalnnndvedncclrlhitliieoanrryeeisoiiifnnrrnllorrofaaelosnnieechhyrfntrbpraaaaaaovleeeearplmaabtaasgroseaahrsrnnnnnrllooeeeeeeeeoobbnyrrrrrrrrrrrrsodeeerniaytttttrrrrrrrrrralccmbuuibuehebgnnnnnlensrrrrrrrrrrrrrrriiepeielsslrslhaauuaaklntsncccaaasuuurtteeeeeeeeeeeoooooooooooooniieeeeeeeeteeittttttttttlfuuvrrryteegbicddffedeleederencoccrllleeccaniidlpddmnrllllloonlllciiitdlchttdpdotvbdmmtllzgggdlutlprinnhhhhnimssssssssyaaytgnbrranammmsnuurallnnlsaoccpddbpitotabiorrtbnnnnpullllllyyeeeeeakenitttcycclotedpiparrsstonabhonnnnnnnnrtlaaockteytcssglllltmbbvtlarohheenlimtnrtmjjjjjriplllllllncorfrrdlecugyillgallllnilwwwwieaetdocdderlohhhhhhskdateslllllllllllllllllllllllllllllreeerrymrtttttttttttpppppoyyseeenoetssssssssseeonmrrrrrreeeeprelieeechccffffrmmluuuuuuncycnprrrrtuuuntttturrrillllllllulssoooooorrlllllommmmyyyssssgsnoffrrttzrrtrrcrnlilyllomatpnrlnooobcnelnreedebrlrtratfrc lemrsreeajutnnnjadadmsaagyrrrpppppnuemmmmssaaanlerareybhioeastpsnsceuoasisiyrdkrubbbroptmrantnmcooossayrayncxuotubgraprlnirdsrilrpppeogcrrrlmtuurcmcrabvfmgltrottvbiglrlmgliechrirsscruoltttiiaeiepfmjo t1abdp3_5accccxjfppv4hhsshpcu1824s14ebm4pcimps116asfttpppsx2fphahhhi7p411pahz711aiiiiiiikxxhhhjo2k2cjjm3ghhhhhhhhhjklssy1oafkmpptttttmpult57333kka12hhhhhptttw1f52cceabhpmibhsr
       01000000012345000010000000000000000000012410003020000000000000000000 0002000001200001001230016001234000120000000100000010000000010000000000000120010100000C01010000010010000000000000123450000123020000100000011000100010123400101123456700010000123456789AB1000100001001234012345678900010001020100000012300000123456789ABCD001000000010000001010100000001201210120010123456789A0123456789ABC00101201200000001234567890001001200000000000100000001010000000000101000000001000012340100120001000000100000000010010012000000500001230010123456700100000020000120001000100000001001000000000000000123000123010101234000000100001000000000010000101100010123400001000000000200012200100000001010010000010123400001234562000001000000000000012300001230000000000000001234000000000123456789ABCDEFGHIJKLMNOPQRS0012010000123456789A012340010012000001234567801000001234012300000012000001230010012345000000023400120012300120012345670101101234000010100123012012300000101010010000000001000100101000120000000010000010000000 0000000000000100000000000000101230000012301012000000000000300000000000000000000000101000000000000120000000000010000000000000000000120000000000000000000000000000100000000000000000010000000112000010000 00000400000135100010001340040100020101000270000002510112000120012DF00001000E000000123456002012000100010005789ABHIJ0000100000001323456000000000102002346CG27890000067000K0002010
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[   1] *****************************************************************i** *******************1*****************************************************************************EI*********************************************************************************************************************************************************************************************************************************************************************************************************************7**********************************************************************************************************************************************************************************************************************************************************wB*****prdwuw*****************1****************************************************t************os****************************************************************************************************************************1********************************* *******f*********************************************************************************************************************************************************************************************** 13-D-A27-22223511--F151C92--13-1---DFE6G321111--141--143-3211132213-22-------1--31---1-1-221-2312247--2-4111123111312--123-1-14-144331---12--221111113-3-2-11-117-42313211kCED1 * c.37.1 P-loop containing nucleoside triphosphate hydrolases
[   2] RQKRORsy*******tT*ggddZt*z******chYURbUbUWZhnWikYh*ywWdlXXccgemie3cp ***u*vi****nqm*****-**ww************************o**t******FF***********bZaaYXXQPjj*gcmlb****L*ZaD8Ag*s*******FDEEEEDIFEDDDDb*yr***vy********UUQ*********morsuso*uw**x*****qnoouwotuphu***yzwsQ*x*************************************y**w******y******y*zy***TjH**MpNNO**kl**koimorwv*aabVUUWigfcgeddbbdbacORTRRSQSPRQQQjXWZZRVUVlj*X**qqnnqtussu*txxZffW*dnVM*jica**xyvqjsfimjpjOVd*x*****OTRSV******s*****************-***********K*******************************************IJFKKLMLEEDEEGHJEGJEDEHDGKHLGw****k*********************************Z*******************yqt**hinkjhgsv****s****o*zk**tsvd*****z***********gbfaUgcbchVSgSVUWSUVockkssr******************************B2M**s*FCBHHH*****************-***************************************************qF************FFSmkojmk*********ief*ayQYZVTrhkn*******t*********************vchbXfdZcj************************rhihRM*n******86667677SCR3232A-A6978457669BC768221Wcjjcomnros*px QQMO***1***P********************************************************w*************************************9*************************9****************************************************************** 1---1------------1-----5------------11-----------2------1-----------------------1----------------------1----------------------------------1-------------------------------54--- * c.2.1 NAD(P)-binding Rossmann-fold domains
[   3] ZWOQXX**********ksyqmeo*********ZQbclVcvgje**g**c****R*y****zpnkg8j* s**h*zk****eZZ*****-**RQ****************k******u***v****h*66***t*******VUUUipoab***GHRIMkhyfHWOND--H*OhY*h*Z*87777776677777DKPOTZYSORRY****ybNT*k*gswgimWUYaNHOIIKajR****hEKFEFCCKCDEB**wdjXYH******************************************r********************j*Z**bikVi**om***x*sukx**qruvlrpu**qoknmkskmmlsswuuzuwwtssswqrYYTsstvu**************y***s******ga***sf****uipvt****zGdXyNv****BECCD************************1***********8***************************************i***44334333343654873594324328386Da***V*********************************HW*****************bfcq*wUWVSVRTRWZ***g**obey*a**rnxE*s*rwv*ny**o***a*WHKKDEDDCAD9M6687879JQIHLnq*******p**********************8-EUnWo321222*****************-****************************************************3************45FfINHJKdhXaVl***geevcuPdXaWdfXb*******Wna*r*****************OMLGKPPJMQ************************XQRR55oXiiPQUU57584554a9M3233A-5586C8665668F777998RjfaUasbedIwOT ZOVY***2*rxW**************************************************z*ywrxUu*uxxw**f**xy**s***************v*****S*************************O****************************************************************** ---21--1-----112311-1-4---12211111-111---2111-1---122-11---1---------1----------1----2-11---------11-1---1----1---21------1---111111111----221--1111123-132---1---1-------1---- * a.4.5 "Winged helix" DNA-binding domain
[   4] 225534897666896C34253331A44L5A56332325245328455C149B7333393244332323 5Z*7*65777797AQWOHI-HS66cUHHHHHMSVYYfM*q6*p*IXI87EB7CBDA6A44JIM6pRduu*W8888999547GC213321262-5-28---3255A566433333333233333423321343423LNNVV111n4*SfcOLTFHAA757987IJJN***o566554484554CCD6711696BLKLJLIMNBLHLLLGEC9AAAMKLADB9C85444454KK4655654456775473465342553364223554444221122464232333532264464354335222222222222243354433327A7A98889A8BA9854998998B8D543796578653658544344-54a4*E888232236BHFG754E7AAA66676676648-ECABAPBB5IC2D77BCAAHDAADAD5I4B85A6976795555555544463E88111111112112233313312212111133B7C9584438EBBCCFB888899FAAA996CCBCBBGA45997FICBADHFFHA79JA99D943334333559AKB9IEF7594-64342-444742654NOSO**3A21--1----1---2-1--22321455567ABCGF7EFB89988BFBBAA97CBB7EC--2566A------57666576575654596-7566866567768457555A887836554344645645846479455656741766676577876115946756DJAD6CV8A433331311123332B7A9B6A7A9C9FFHICEDFDCDDEEGBI2111111118BACB55585ABB87CBB6F69DCB333352B588AB9911------221----2-3433323222334333332-21---2----8C3 *******7************************************************************v*************************************W******************************************************************************************** --------------1----------------------------------------------------------------------------------------------1--1-1-------------------------1-------------1---------------HA34- * d.144.1 Protein kinase-like (PK-like)
[   5] TUTTaaYaaUWaZbfdQXXWZbcciWXfYafbWMMijPWZfYalzfj*Za***mhchhgfYOTYSClT Rv*M*QWhWWTPMU*****-**VV****************K***nsgWQaXHdgnPRa99***S******nFHGGOHHRHMdcVQSQVgdag7aQS944elfrX*rwdkABBBBBBDCDEEEESYaWiroTTstX*****KLK*R*******otllfVZbddu*d*****TZTSRVSdbVPWcVgXaOLOahh********g******llgecd***bebqeXXeYZWYZ**aSXPTQPPPRRRSPQOLUPQWNUMSTJROPOUSQQRSPKRQNHQYcVWWNQaUWVYWVVbcZWYXUYRTQPTQQRUTRQQZaZTTTZTWSZmkksfbgdkipelYmi**UXeXnXzNTafgha*z*anbUdaSQQXgNeZkd**wy*QdRNmz*****y******YabcbZcZcc*-***********J*wx***********mlmk**rluzjtsfeffffffskjbm***CCDFBCDCDCPWNMTWJMSKIIMNHE9FFRkk*kNgjYUq*******z**z********r****uvuyRZpu*qz**o*s**rwq**ogdqyognfagdgskq***p***meu*k**srlf*****y*y*******j*XWWdPWYWXgRpYejnkkYhlXRXbsqvwnr*vwivsvw*************zz***7-R*rq*A96BBCyowtoutlwutmutxwm-uljqqpwlrruvqjkkjjpvursv**qprloploloomvqronpnpkojmlh9xqqqxqonpnvs98TrJLJKK**yz*r*llcbaXhUbcXZYjRcZcceefdkceV*u*****************STVSSUTSTpsrqunonsnwv*rvzx*****z*xjaefGE*jnnsrtoDEB9BA9BcCPAQF7D1IEHGI97FFFEGE7OEBAATTPQYSQUTTr*PQ z*jo***4***m*****************************************************xtxe*wr***zofsqq*************************J*************************K****************************************************************** 11---3----111--2---1-147312--3-1--11-3-1-3111------1----1-1-------------------2------------11432--11--41-----------2--11--1---111------1-----1----21-1312---------1-112---662-- * c.66.1 S-adenosyl-L-methionine-dependent methyltransferases
[   6] LLKJIOuijnnpoqptKZdedMRmteZpepeXFOIHFLMHKJFCJHKFDIVWPOOTSYZaTVTUU5DG es*b*PJcfgoTRT*****-**BB****************Z***ssaOXrkK***fcu88***Q******k8BBBHHG9L*luWXHMMMLMG9PEE768CoRid*a*hc86757769975666DkrfmmkYXpndqlmefGGDvm****vzocjhigcnjdiimVr****beVTZXbhdTQbfbaSSPOEYkcsuvwxwm*b*wvvxxnijgecxz*YdYhcvuUUUQRS**YcccaccdecddcdchkffbWNLBNM8DEB9ddGGOOHIJPT8NPQQNONDGFINLEEEEGEECECEEHIHHFHHIHHGIIHKDDDJJJQPiVRtbabfaZcnagOThgNYeWgVVOBOKLaT**s*WHMfWYNRVSDHEYO**uu*GMHGIv****xjm*****jorumguknt*1***********B**************hqY**********rqrrrrrrostimkmkDCEDBAABEDA9ADCC7A8DBBBBDB9CAed**kI***q********************Y********Ld*****ysk******tmrcVWR*WNNMLNLLYVYp*id**aiidfThogfhGYPYXZXTcNcbfd**X*RLLDCEHGIED9E9999899TNMXtdhqlkn*u*Z*jmjszusm**qlitxn**x**52GSjjl545444uhvpTokwxxwwwv*wx-yyww*sutxwywvtxrxxv***oloubqonlmpponmjnrlms*eegfeknMFfeccceeYcecbABEdJNJKJdageW*py*ONLHHIIGHHARMNN*****b*dnk*v*****************WNVPOSRQNefghwXZZXZummrrsqqnyooeeeKKLKMKYIwwPOef47743655J7K4545D-A4F97799899HB9A7334MGGGKPIPLOSUBL YYJL***2*kjDhl************************************************oj*SeWTpUSowxfcMccgutu*sZhc*****************9*************************9*****z******r***z**y********************************************** -----3-----------------11-------------1---------------------------------1----------------1--------1------------------------------------------------1----------------------C1--- * c.3.1 FAD/NAD(P)-binding domain
[   7] 3313376BBDBASNLF5355563AN66C7GB625523464434BEDD943rIC28Q5847732121-4 Wd*F*QKVUVUaFQ***z*-y*DD**zz*z**********C*l***SWOawMhjiXMs--***F******TE999JIA6BiqPA7HLBWXca1WBCJ--9dCKN*H*dc1222222111111155A6AJ8D9BCFAA9FP68Dy5tLbnRQ*J5461222--6Z5iVVoJ11111--1---2MBIB8772KNYsuttwo**Wu*tru*nvqqmcrs*RScmnQMQNNOLJ**8HHFKEDCDDLKGFFJBCNIUFbCyqAcE9MabCAVTNGJGEKnxkEGDXH78ILKLMBWKLMLETG9RB9N9BCFFCFAMBEKJLECDCIydh*feafglhVkOKyihAFCTnNsCCVBPE5**hTVNKmGLNZNh7C8YDh*oog3-2-Dod***fWK*ogkmKJKOKJKKJJ*-qk*ee*jsX*o-*xvu*v******r*RrRjhhaigYabejhjjjjjjUisMEZbf----1-1-2-4V111111531-111---71Or*UEOso*********ttuq********c********3Att*ib*wU*jsl*hLmkGPMQYI56GA8B7ILIgdbN**sRLnjRfgehm6jcZhhXnPWmtkw**QmF34714333382323233329O7BDLKZlUWrTtQdRRW*dibhmicXZgadfkaqj--4RMJR1-1111lgjbXuQsrp*xr*wxp-qpsrx*nj*wouthktjig***lka*bfgcgbjgbfcgkkiij**c*****N-f***e***yThX--5F39333FAB8KW*RrNBBDAD7BA7999G7vstwvZXFHN*Q****v***m****l***nny2e3sznHdectYeYbe*igrlkvlopil***834321QFfjIKLM2221-111K47---1B-1-55A11233168122222EKC777G777AZ3C GKOS**c-U7BV*w*jatr*kleqfwroo*vp*srpgmjrbktiiw**hvzs**dxp*pw*rlhggfeHgibifekiSghbimldhYjb**gapj*OMQjO*q***Rs************************g*********************************************r**x*wx*******w****** 1--2---------1---11---1--1113-11111----1-1----1------1----1------------------1-------1----13-3--1--1-12-12------1-1-------1--------------1211------1-----1------------1---1---- * a.4.1 Homeodomain-like
[   8] LLKLNIQRTTUTTSTQNNPNMPOdzdgjhfmlVSUUTRTSUZUSZRTWUXijiRUVTcbdVRRSRFMP qqyQxVVTXWYXTUdxiYY-YkPPjdYYYYYfkmonolz*XnbpbZWWUVRTZdbWVSQPgglSfViponULOPPTRQUQbbVZSZUZnkidSfbbYDEbkanflinkmTTTTTTTVVWUUUUicdeddbcbedchkkkkNNPjSogeddecYacdZZbXXWaaWekffcYWZUXYZXWUWXhgbffUVUflquvuvvuuxsvuvw*soloomput*kjhthmhsllmmlppkmllnllmlnnnmlgklokkqcgejjghifklkddlljikhhVoqrifihiljegheffgeeffehedhefegffgggeheeeeggdddhiqlrqsvsrquuuvjhnpqmmnmyegdqfhmWXedhneaiedbdefjVcbbZtlacrYaZVdmjzmuxeijklikaaZcaaabaal5fhfijfgfm*iRknnjnmmpromrihffacdohjhhgfhXXXXXXXXacZVYccfQQQPPQRQNLWRTRQRTTRRSRTOSSOPQPggueXjunouooqspppllljpnptoppnlmntzp*v*WevqpjolmglmmhimliimoaijfbdbbcbbefhrnjkrqomamfdijomhWsorkplsrpmnolsndmXRSTURQTSTVPRQQQRRPSYRRTUgerpnlsqoipvwlpnwmjkkpkljjomlknmZ5aYeddTSNXXXrpqrrvnzzyy*xwpyy-xy*yxz***wy*zwxxyxvwsvvtvuxuruvvtvrtowtvuvw*wustutxnMxsqvuttnuuuuNMkdYYYYZmnmlgl*lomjmknjlolZjjlkkgfeeheeZaehklnpmklknmlkloojmmfedacfddefqutxrrqsrpvqyxkikpmpplmnrpfwWZdXccaeZYNNOTOPOPXVWSMWJO-NLQLQIIIJILOKKMLLKKchbcddfVcdUhXk **Ui***E***d********************************************************ax*z*****f**y***z*********************Z*************************X****************************************************************** ---1-12------------2---1-----1-----221-2-1---1----1---------1-21221-2---------1---11---1------1----1-----1-111----------1-1----11-----111----------------1------1-------1-224-- * b.40.4 Nucleic acid-binding proteins
[   9] --------11-1-------------11--1-------------11-1---1-1-2-----11----11 -22-1-----1--------------------------------1----1--2------11----1----1-----1-----------1111--1-----12-1-2D11--------1------1---------3---------2--2------------------------------------1-------1-11111------1--------------------------3-----------------------------------------------12--------11--------------11------------------------------1--------1----1-8-213-2---1----------1------------------------------------------1-------------1---1----------11------------11--------------------------------1-----111----------------------------1----11-------------1-----------------11--1-----1----------1---13-12--3-1----------------------------1--------2-11----1211---1-1-------------1----1-1561111211-311112411151111111------------1-21-11-1-11--22-111------------------------------2------1----------------------------------1---1-------------1-----11----------111------1-----21-----------------------------------------------U-1 ----1-3-----2211-1--11-3222-------1------------1--3-3111---1---1--11-----1-------1-1---------12--------1-1--12*****************************************************************-313-1----2112-1-1--1--- -----3---------------------------------1-----1-----------1-------------------------------------------------------------1-----------------------11-------------------4---------- * b.1.1 Immunoglobulin
[  10] 6635419DBCCEBCDA2846635EJ77K9EJA3341-121212AH87G34NEA-665777498A1-52 fu*F*XUceefZSP*****-**PP****************G*v**uXLKqcJqyvYL*34u**N*z****cHNNNNONA4BXV44633IGTR-T98A--LzOcl*Q*Tf44444444468787DHFAMNKFHIJJrvudf665*H*suyefZMQVVFFHKNGXSIw*n*mCFBCCBCIBCADnQhFE779JFXutwsxpt*VvsvvrnTPaYedqttDFEcSPRQRRSUSqgFPPPPPOPOOPPPOOWQQMPHKGCKQFGJBJVVEFQRB8DKCHECCKJG5BDBHKIBAABBCA8A8B5555555555555IAB776788A887PUEDDEEEIHIGLKEE3GJEN7GD4TAC52QK633DAA6199H94AJ*3****y6977At****LERptholKLKJLIJHJGg1qr*ur*j*Z**3*zzuz*v***vv*rlupXijUPWVZagPOPPPPPPZUTVPToW5556533345798ADD7BD979AAA52579gr*lJTmfVf*******syzn********f********8Kvs*fgkSRwmuh*aNXmCF7FkI8878767FHKRghgjRSF79A6GF9894LMF9FCQDCbYgY**9I9AB2664524526222212275568DDeYOgXkoYtaPlhqjikslmkiZqkmrbqz1-5LUMN-11---RSZaFXHNZaZNZWaSM1XNPTRSRQSSXXVPOMPOMVadWYumOOLLLMONONNPMPLLNnLJLNJOPA1PQQRRSQPPPRO-13X7A777ZmhjAi*TiA9ASAL376689898svpusYvFUVub********yu*t*c***A9978BA89ALMLiMLKLKbWURQ*******qvrSMJM21CAnnRT*j32212212I37--126-91A2334222495462213FCEDAEFBAC7pES nfKV***-*vnY***************************************************y*irpUujf*n*roVtpm*****bgd********x********5*************************J******************************************n*********************** ---1---------11--------1------------1----------------------------------------------------121--112-----2------------------------------2----1-1-------------111-------------5451- * c.69.1 alpha/beta-Hydrolases
[  11] HHEADGECHMMLJHMDKTPMOLIOVKMQNLWIAAAAAFNKNLHGLEFOABeNU7CEDFA8DJHBC18D JKVG*RRWcdfFMHmRUNM-NiJJW*NNNNMNrnsor***KzU****NXmbN***KNz44kaeQ*g****aTOOOlZVFGdXcACEBDCCGC5G562113H87APFCEHAAAAAAACCDDDDD8DA9DEBCVCLBgnnsrABDpbpnnpcbgPWRRKIIMMLRhGk*n*a9HBAAACKA9BAvhWWVac5YKjz*******fx***y***rnms*x*NRexrbWfabcab**HQQRQRQPRSPPQQSTQPOWjeSWcgVMOLPjjJJjeGMLMWOTTXTUUVQOPNSSSWVWYWWTUSUNNOOMOPQPPNNNUSPVSQNNNTXzYi*cdbcdjdUZVdkddLTUP*PNTFnUhIG**YcJPXZKIQOPbCPTIFLkPPS9DA8Gzs***VR***v*u*******w***1**********b9**************WNL**********aXaaaaaakpoTbpc*55444554555454553554444433353GFazMG*********************************FW**************w**MWSV*tJLIIIIJGINj***s*Ukju*Un*qn*BeaXuPXcXVccVip*HjMMMIJMMMNKGBGCB9AAAAJaMGMVR***p***V*i******s*************7-HKYJm322333****y************-************************oz*************************Z2************55CQ69869TUSSNU***dddrYnIQUOPYRUg*****e*Ujd*t*****************EAD88ED8AS****************notolWYVICDD44rpIIDCFEABBAB999N8I89G76-1352435222242943333PbaQNXyVaWKZC6 73239BO-G4648MH9EJCPBBBGPFB97D9BBFA6B9AC9ABB79FDFMOBOCDCFK8C8B8979AA58A6B8897BG9A887BA7788HEECAG769A5OBFI91Pjr*******lbdalsh**f*e***7***eqhc*at*gSmZbU*YU*b*ty*PXml***k*s**Vl*fBfkC*BEDPJ*Zb*DjJHIlgSfK ----1----------------2-111--------------1----------1----------------------------------------1--------------1------------------1-------------------------1-------------1---6---- * c.94.1 Periplasmic binding protein-like II
[  12] ----1-1222222222--1----1-----J3--------1-----1---64-11-1132-11-1--6* 6791J------1---------1--1-------1---112--529485-4423698-1---7A213-18EA33-22411--21---3-2DFOD1B33---3I559TAUCK--------------4--1------G-6AA74224E3-1--1111------------11137------------232--24-1516666655866B57D759561276D252632-6775849m--------------------12-11-1-121----111-----132------11---------------------1--------------B22441111111-12K143-BA44-S-142I8-ABA-234-12111D---321222-----------------------------1------E------1--4------4-11111--1-1--3-1--------------1--------------------------------------1--222132-222222112522251-11211---25D---121--1-121----------1-21-----FU342----22-1--FbJEC5k1565D7I5983--3344444443444344434233--1--38I2233822132311313714-4639---2-12-------33311--JH6-62A-3-L2-8269488J88222323111122-4-1---3-42--26--5-44-4244--555355555445---2---------1-K--2-22-------2---1111--12--1K337123-21-112-725111111-11--1-14444411-12462333512--------2AA6578-1-11111221------------------------19A224-5----L2D 1--145e-xPU177E3453B4A5A6552232228873232322434234557745567478743421222223222222232232311153441231-1-313311-vt8*****************************************************************-EG3P356WEOeXm3UU1KV*g*m ---1-------------------------------111-------1----------------------------------1----------1-1--------1------------1---2------1--------311--1--1123---2-22111-2--------------3- * b.1.2 Fibronectin type III
[  13] AB74779HGFFGDDH8GI87687KC77C9B86E796A9AAB9BAB95F9FcNUD665A889C9B6336 om*D*KLMQQPMJHNRUOP-PWFFVtPNPPPPbdecXhvmYabskqrOYRQRkhhLHg55ffqZ*r****VSQPPacbJMSOcOGIKKljvhGrEKC13KbOXbvV*cx66666664566666ITSHTORITUXXSUVfhFDFeQdbZWVVULLRQMNMRTRPUOjknpdKKHFLFFLEFHJfcOGGgeLeTahhognemkYjjiejkojhicbgkhYbefiWSquuuspn*FLLJIJLHKNLLLKIRMORTSbnFUcJWQLUtpXZiaWQYWSONMQIJIHJJJGDDOMMMPPONLNOJJJJJIJKIKIIJOHIHFDHGGLdyXo*ggfggjhsjjfoppYdhglYdUJgUWcM*xfsXZodahyppZMWRaLsobbk7BB9BeU***kRafohYeYcYdYZaZbaq1ktcZlolei*c8************efWWWdjjkdjmkbaVVVVVVVVfiifPdXlFFFA9BBB78DDEEEEFFFEBFCCDAAABCOSiVMSVQSbuqytxqqgfhe**x*qqssZrs**dqqnELomgnbbhcuudcqmXalUbYSdQJJMKJJKRSUncnX*kaQSXZUakSSPJebgaegpWYnnqmtyRiPHIGGIFIFHGLHLMHMMJNMNINUUSqv*leeoQqapnkkklecqqihlldjonqq91MaRVcBBACCC*pztfra**********-**********************uvgge*xuxzz*********wwoptnkpvZA*rtwuvvluytu99FPIKGFIRUUTgVsWgXWWaQaIPTRQSZbaQQQWQNUNNJocjnoldbjkdaecZggedUOOTQTROORdkmxkmmollonsvfhkfnggYbbPPQPDAYRSSOPXVKKJKKKIKMGI5685F-B688A86AAA8HB7AA777TemTRr*uwsShOM ddSV***2*tyUjo*************************************************x*yy*cx*******m**zyyzuwstq**z*****rzxn*n***Ky************************5*****************************************yfk*h*gednr********x***** -------1-------1-------4----------------------------------------------------------------------1-----1------1-------------1--------------------------------------1---------3---- * c.55.1 Actin-like ATPase domain
[  14] 665276dZdfogZaiVCPED978E9EEABADD52542275652MQC9C62JB91AABBJF9ZVU8-22 LSqD*LIfjjtJQPXNOMM-MY33m*MKMMMRcZZbs***KlQ*ZdSMEaT9***QBa44cbWStW****BOHHHdTL58XCQ59658UTQG3M334--AUDIHtFTAc32222221212222679997765559PUVQP765RNDAFFAD85756564985B84AFDK8142211231211PFG76B9DfG*********e******kSzxk****KVVfSQPWUWUWU**MWUUVUXSWXUUVWWbUUaeJHZEaeDOGCKijTVlmLIVWUVRPLDCC87469CD577776567577877A77878877733553423B8D2UhEEEFEHFEDEBPZZ6BB873433E2463tkGDG5DGDFBBH9714F7C*SSo4GB7GeL*lsIARUaTXHKONPJMRKOKr-ba*WX*Z*LoR2*XZddkXwyscgpUOWG9IWB8ABGDHcVccccccVglNHH7J664766662265BEFF9BHBAAAAA74B62CasNGWWMPo*******************k********3F**tCDXKKmLTNxTQeFC9CEdF6667768496FDMGNW7F6A6DGD69C5IACNCBH95JIDHWK7JA7555HGGIE858465454446556FFUQRIHRR7XDMPWTWZNQOWSTJJNKPJWV4-45A5A11-112*x*rW*f**********-******************x***z*Ugm*****************som****H3tXYZccaYYbcb1266SXMTSbbYb7BKOeGCDEDF59B67789ButqnxLlFKMuJ****m***L****MxqyoWdYVoaZW6IPNTNPOQPTPOLNYaSUTUSJJJ85552395DD9998-1-1-111512--------32-11323-2-221---CF9A9DBCCC6QAD 877BobT-*UMGSXn**************************************************e**f*np*s*y*g********ksy************o****4X*h*******ulqqt*u**a*v***3***l*pq*l***h*uod*dY*o********************HaSN*WYVXq*******wm****p --------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------1-- * f.38.1 MFS general substrate transporter
[  15] IG778AGCDCBCDDDGCCDCDCBDWPNQQOSP43H55755564BF6DLEEQOI46C66CDBA9784DH QXwIeIIKMNOEFFUPNRS-RbCCaWRQRQRVdRTWUXhjETIULKDILGFDUWWFKL66PXdHSQUaYZJ6AAACCCA88GQMKNJOYddc4RKJ51-JmRVQ*dhNn77777777777777FKMGLKIKKKbIfcdYaBBDVM*oornmeUSWWWUVWTSceUhw**iORPQOPQQOSQORNPLKGF8MTQUWUVVUVYRUVXWUUQTSRSXYUVRSUXRQQGHHHGGgSKKKKKKKLKKKKKJKMJJJNNBC6DG6F779EGBBDEAD9HE8IIIFFIIEDEHFEDEEEDDFEDEEDEEEEDFFFEDEEHDCBCBDDDD8TOESFFFFFFFFFHGEFE6JHCRAKGIW6ACDQNIQEEIGBCIHG9DDGYBj*nozGFFEEli***dZhvnt*tTTUSTRUSTSn1t*yq***xbry9uiikwvxy*usrm*llnwltdYcbkk*VUVVVVVVXjeQVedbGGGFFFFECCCFBDDCABCGABBB9CADCIqu*pGjtqb*******wnqqo****vsvviv***v***MV*****mwjz**t*dhvvmbbdoWMPPOPOPWbjlszYTQIIGOO9YMHFI7QSTSURRRYjiag**UWKEHDCDFGGHG897877778KHBNWXWmlSjpl*Xsninoutxbsnspprnkmrrq*62FYeVn975777fdadUeadeebehbedd-edjhfdcdYdedccbddcelnmhfPRWngjliknlljlqpmljkbccccbcM7dTUTUTTSVUVU99FbFGFFFUSQTje*ahNNNSMQHPNNOLIJPbZfdeRdSbZoX****y***n****uphmNIJJJMIJIbdfemZZZaZmlufgwvqpupqegiTSQSLLUHffRSVV33433332A5B12233-3333352444526233333KGDKMJIHIIJZGQ nfUY***1***Qux***************z*yz***t*v*v**wst***********z*****mwflhPrnlkmxsofmsl***sximi*******sksplvy***C*************************D******************************************s*********************** ---2-2-1-----------3-1-1-----------212-2--------1---------------1---------------1--------1----1-1-----1-----------------------3------1----1---------------------1---1-----5531- * c.47.1 Thioredoxin-like
[  16] 2213-1513221341313421113948G2A5853831-455369C6S875PPQ273567421231-16 46Y4E33344643369844-4B1167444445AABBCECK143A252-4652678422118852989BDJ343332313215444424678835557225A349M5V5A54222245557777A46132232462FCBDI454I6LETQOFJABBEAE99ACGFEPSWZg3696211825738473425348388878BC948DA9BD97989587B6367585345469CB432242324344333323566335366121522--225311-14323333343233242541323433122333232232445333222349747555556677558454553F76233334944687555957553236J5c821311133538462526698866766665765-5758688459525646576BAB85AE3566433332454222222221563384B443232232245443432A3122243232126564144346686755333377467688696253643244455142455447467724234222222343436464ICBA5A76796665BCC5AA867A9BArz8922222434342121141-114133455256843B17868899776377654735659211855A12111122132264343411443-44432322333223534434323523423234123633242334212112121555555455656111667654373494A132211312211112155555632132564565796765558835433444434336885546544954386866679B8232321A6DDEEJE2444344364221222-433341122213123311135635112223944 y*n****2************************************************************g********W****************************a******************************************************************************************** ---1---1------1---------------------1-------------------1--------------------1--1--------------------1---------1-----------------1--------1--------------------------------211- * a.118.1 ARM repeat
[  17] LMG9CDIKLKJJJJYJCMKIHHFPOMMQFJVNLGHFIJGIHGMUTKJVHQORMDLRMHMLNJGGP1HN RsyO*OJKOONJOIobbbc-bcLLl*dYdddahfgfgo**PkilchRQMSRJqjlVQf99vioL*d****TKLMMPPOAGOWTIELHIhdZcCeKL444KjTffzUoTjAA99A99AADAAAACLNMQSNKQPPIgnojfA9DiXaVbUWXeMRQRTUSSPPTVQShdrYRTRPQPPTROSTVUXONFGJVWmstwtwryviuyttxweoomektvyfkcjYRTSRRTRQ*oLTTSSSTSTUTTTTRWQPRVKFEBIMBM6D8RTJJKMAJ8EMBIGHAAC9899DJHGIIHHFJGFGG8888888899888KGHJIIGGGELrXanggggkikReRTnkiOQPOcSYDKbTVROhdSUVNLWMTTQZOKKIjJagaabBB9BDYa*ryUWSngeicXZZdYXaUYYq4fhtdi*arn*X9shhosv*xq*v*jgUbRglokkkmpo*YYYYYYYYXccUPgalA9989AA888377577565955765A7D8FPRjPSp*qgs*******z**w********b****ww*uEKjirfkjZV*jrf*oUYZNPNRlUJIGIIJJOLQUZWMbdWVKVURdcZXVEefZgYWgXUZbfau*UYSJIGELLIILFCKCDDDECEOPHKLLMhbRVVTgQXVWacYbZYRcWUVZTWdbYbjA2AXRON674656ogngcnjfhhifikjjf-hgdhjghhighihgffgghw*vovmxZjfhjkkjknkijkijg*YXacdcbN9ocddiiegjhih98COHKHIINONQWRoasKKLIILCIHGEHGGLXbaeXPUNSQfV********i***whrspQKKIIMKIKJhWXhWbabbfjhhjXYXcXddVXVDEEFFDUMccTSUW33334334N6724222-2332522333354343111FGMIJKKIKISXRR HD7A***-*bdPmqqr**u**********rrwu***vz*zwz*vnr************xyxwgnpYhlaiicocmicOidjomihrTWcu*j**v*qjoqh*lu*z9***********x*z*****z*****E***x**y*****v***q*wm**********************jw*m*lknux************** --------------1-1------------------1--2---------------------1--------------------1--------------------------------1-----------------------------1-1-----------------------114-- * c.67.1 PLP-dependent transferases
[  18] -------2----------1---------------------------15--1-----------1----- -14---------------------11-----11-------------1-------------1---112--------------1------55341422---1221-322-5--------------122123222322222-------D76755344334443433334A955333332233332-----22--------------------------1-----1--------------------------------1---------------------------111----------------------------------------112222222-1-2-11-1111-1--5-121-1211---11---------1----1-----------------------------------------------------------------------------------1-------------------------------1--11------1----------12-----1-11-4-2--1--21333343122--2-------------------411--232343333-111111211--1--7-21111-------111111111--11--12213-12-2221111111111111111111--121-------------------------------------------------------------------------111------------------122222-1112-2-1---1-----------1111111----------------1-------1-1--1--24221111122211------1-----------444433--------12------------------------------------2111 *******7***Q********************************************************l********m****************************X*************************r******************************************k*********************** ---------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.7 RNA-binding domain, RBD
[  19] ----1-345677675311-1---4211111-17176A55787ASFAD*8EfbW1255B662247--7B a**1*123334331C8A99-9755HD89887CHCDCBAaV5WRl6H37724188A415--MG91mIcfYoD1333333422458AICC****5*RRK--f*Mnm*l*U*88666689967888TFCRGZEFKahJhmop*111*3*f*npq*OTJICE87CBYOLv****5K4J656f5G96TF888A9J88CEDECFEGIEIGIIGGEG99JAEGG8A7C958677776ND5444444444444444444452224324221221125223132222211231131111111211111222222222222221122211118D6UE999BBACFBC979AA7A9CCH21B6E77DABE86957624854CNxL*SLMR45244QFxfoJIHJFQJN9A9B899A9AB-FFTDFfFCDpN5RHHVZVYhiTXXHJVQZNPECFBFKHHAAAAAAAAGEF7CjLc44344223128G52DH25D56344232333ENXHD8FCBCVGHFKQNCEEDFEXgKIKGHIcSUMOTQBKJGLUGGE9KAKPLCFMfQFMRN86888877HBPBIRa*nsPQfVLq*RSXHqbriYZhVYsu*r**RX666626655663534544354F48CKJNJBaUcdKjKIQJMKHTQMIHMGKKPQGTb--8OIEO111111EBAFAE8EHJGEEEFFC-GEFGGDDEIFHDGDCEEDEEFEEG8ABHIHEJGIIHILKHJGHKA6CA87991CFFFGFEDEGFH--5P8C98AA9C9KCvCGA9777644343622BCBBAB8A797FUKLMOPKRMJJKFIHIGE2333333337KUTOHIIHIPVWRQONOHNHJIIJBDCD--r*fehhopJJKIGIGFfR-----------1--------------BAB458699BJuKY UUYl***2***o**************************************************znuinrOuhwupqkrYntprp*mnzxy********ryzx*****D*************************o******************************************n*********************** ------------------------------------1---------------------------------------------1-----------------------------------------------------------------1---------------1-----1---- * a.118.8 TPR-like
[  20] ---1---11111-1-1-111--112--312--1-1--------31-2233132--1-1-3-111-1-- 1111111---111-23422-21224121222221112133344611212-4-12212-2122--4421312-122----1212-1--12233-211----1231131-2------------1-1-21----112134454111315-721211-11211--11-14133--21----1---1-----1---13555555342454554234424435243322332222141-11111111122111111-113-1111111---11131-21211-31211---1--------------------11-1-1111221111211--111112112132-11132--1-1---11222--------------2112322--1---31-11211--2-21111111111--4544352312------11-12---1----132-----111111111121-12111--1------111--11------------1-1-2111-1-235525473333223333331422333111-45312-11122111111---1311------233211113-1-22-22211--212312-3----1-11--1-----------1------1-11---1-112--121212111-211111223111----2---1------11-1--131----1--11--11--1-1-1------1---1-----------1-------1------------------1-1----111111122--3------1--------1-------3-----11113512-21231112111111111--1111111111--13222122223-------1112265--------1--------1-----1---112--1----111-1-1111112 GEDK***-*VSDtp*chviefgffhcghibhegbdcYibhZhijkhggigheildagjekkkfWbdcaDQbYWUZgmOhhbWVWWXWZdkzlhplymildafn***6********************************************************************FUTU*KJDKL****s*lXa***** ----------------------------------------------------------------------------------1-----------1-------1---1---------------------------1-1-------------------------------------- * b.55.1 PH domain-like
[  21] ---9-----11111--1-212-3-2--312-1-11-11-----33-31-2465----21-----1-d- -9I-B1--111---2------3--2-------1---111--V9P22-1---------3--212-8-26331-------1----1-3142214-1------41--45423--------------5311241112915332A12242N9H878A11112-212-361CMGMF121211131211265-12--1-1-----------------112--------1--------33-------------------------------------------------------1-----------------------------------11--222211--2---------2-3--1-3--1--21--4-111222-15-K1121-11-1312411111-11-11111111111-242532-122--2111213121511211341-21--12211111111211111-3--------------11-------------31-1---32-----1--12132---111-1112---5------141-112-1-3211A-1--21---------1-2224-4--1--21------242111234-36K-3133222222-111-------54113--1--111221--6212363134233213256---2251---------3-2---------1---1-1---1-----11-112-1-4436-------------------1----1---1-1111115111--2-----------4-11--11----------1-----2114-511-112-1-1-1-22--1m222112m-1232222122-1232111-12---------3133--111111111113--------------------------81-3---421-612 *******A**************************************************************************************************d*************************p****************************************************************** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------8---- * b.69.4 WD40 repeat-like
[  22] -------------------------------------------------------------------- ----1-----------------------------------1--------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 948C***-7-2-22A-131---111111122121--2212212222-21243221223111111---1-----3-------111------1313121231-2-321-vY******************************************************************1eL6G514C6EnhZ2R64759C87 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * g.3.11 EGF/Laminin
[  23] -----------------------174433234--1--------1------------------------ --1-1------1------------------------1-11-1--1-------3--1-------1--1----1----------3---1-11---2-1----111-12-52--------------1-----1--11--22-31111---221--1-111111-111-1112211--12211-12-----11-1---------11------2-22-----111-122-----132211121111111111-22132-----11-------1-----111----------------------------------------------1---11111112-2-11--1-----1----1--23-1-1-2---------1-1---------1-3-1-1-12-2---------------1-1--------11--1--111----1--------11---------22--1112--1----------1--1-11---------11----11----------1111----111111------2----1--11-11-1-1----1-1--------------1----1---1-1-----1----2---1-1----3---111111-----------------111-111-2-31211221212111222121---11---------11---2---1-111-------111-1--1--------------------------------------------------------1-------------1------------1--111111------31-3--1121-1-1--1-----1---11--1-----1---1---12111--------11111111-------------------------------------11--------1-- 22--521-43-331C448643437555224667547332213475343-378E967568333-12--425373224536623242423288341-3424431512--324**********************3******************************************1664L-1111A3695351317551 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.13.1 Family A G protein-coupled receptor-like
[  24] ----1--1--------1--1-1-1-111---------1-----1-11---11--1-311-------12 111-5--1------1--22-2---122222212222123213-241------121-12----2-1-1133----------1----1----------9-------3-1----------------3-----1---1----1211-1-1-------------------2-3-1-----------------111-----------------11911-1---2-1-4---------------------------------------1------------1111-------1--------------------------2-1---111-------------1----11---91-1-----------1-----15--1-----1--------1-1211--21122-----------------11111--1--2-11111112-1------------22222222-----------------------------------11-------1----11-3--------11------111---1-----131---111311-1-1-1--------------1-21-1-11--11-----1-11-1-11212--11----111111---------2-1--12----1-----1---------------1----------------1---------------------------------------1-----------------------1---------------1-----1-----123-1-1------------------1111-1----1------1-------------------1----------------11111-----------11----------------1-------------------------------111--- ogkq***2********************************************************yspvWurpywwt*bxxsvyvu***************n*****L********************************************************************o*********************** -------------------------1------------------------------------------------------------------------------------------------------------------------------------------------6154- * g.44.1 RING/U-box
[  25] 443535755HHB656E45454449IbY8E8H7575763778868654N77oOI546526884598256 R9jVEiRkNMJnEXFZNEF-Fo99XWUIVVSBllcnILjcBHNrDBBMBA*FOKGFJ*76NIIBIBQWTHDGAAAOHBA8EE9A8BMDFEYE6FYDI33CJEIFbMRDDAAAAAAA99B9A9ADB98NJMFCJCLADDFBAEAOB*MRFYL*BCCCCBACAAFZSSOHoeABBAB9CAA9ACMVTIE896TUHFHFHNMObPNXPPPUDQNNGDNJPvpRLDGFIEEHEGLGDFGFYDDCGGFFFFHBGBZFDHGCWTHcBSAEEJGOFJJCMGCYvbFKCQO*O9IFOICMNJIFWHKGFGDGHEFGJJGHDCBMOJ99AB8gJDNFGHHFFFHME*GTTDDDbDOWCCZGFYHvkmsdEFCBFMTHD8MBJDgaLLMBDCALDEhKYQ*FHEEBHGHKKHHJHILR1ZaUJMVKTJMECJNNOPFOSSPKcRYHHBWGIEfJQQLD********W*kpEfFDCCA99999887EAB788AEEe8898FBKFAMAGJADDK**NMObXNg****aZNQJTPLDMEgfHGNq9GPOsUP*KKRecGKVKImDCABKKEICEDDD*xWiFQEidBDEKQFHBFMF8LALPKUrUOEEGFXcBKE9788899A8B89A999999DODFGGGGfKVWHOPUIMH*ZjeYYKcSUlK*eVQMN72CDMMM987667HHLWLRHZstaePYaXX-rWaRqvRN*awRcaedcaNdLQJHPeGKUILJUJISZZQPIKtO*******F8oWSVTWRSUHPJAALCBDBCDPCMFMGRGYRONEEIEEGFDGGJFIFPJMFJRQdkgLRZMNHLSKSNJHQpRVCCCCCCCCCJfNL*QRPPQ*PXcjaNvr*jq***GFEF99*8GDVVMF3443433597CDEE69-B799A857DD7*956B888FOAbBADADA9LAD *n8E**T4*cZG*dpeirhqTYUdVYlTTXUSZSQSWVSTRRWSMRi*VcTVj*STb*bUUYoTUNLNDmNKPHRV*ASSLRWcORPOQ**rir**QLQWL*gWh*CX*********yrwpw*u**y*y***L***mqtn****uh*tnl*pk*s*************ev****jM**a*XVbgd********o****W ---3-112--111---2--2-2-111--1-1----112131-111---11--1-1111--1-11112-11-1--1-1----1-------111--1-1-----1-3---2---2-11---1-2--1--------1----1---1---1--111-1--12--21-12---2-62251 * c.55.3 Ribonuclease H-like
[  26] --22212-111359F151111127B55431B135B133434321B399AQVCG547545441113-21 PKSDW86B989465IABBB-Ba88EBDCEEECQLMQOIcQ7DTW89B5A895B984C922FC83EBYRWQ75555B8663EC7ABCBBgfUY-XW*F--9cBHJtHa8R33333333332222FC68MENAEHBCDONCP1-1F3*OPbHFU8PDD978769AYGVcqgN492434281412HGA22434GLDFFHGKGMLEIOKIIO9EEDVHWJHWFKJC96GBDBBFSJ3A787868A8BBAC745562IBBAIK967MBLF99HD844578B*99A9P8CD7799C99A7796969BBAFC9AKGD889998886575FK9FQ898EEHBCDAKNEDa646H9G8AFARAJRTJ8BN756C88JN36FJ7YZPQK35545VP*dy*dUYYXVYIMNPKQMmKSU-fqaXZ*oi9eG1ZOPZfWccRWZQRfDLHO8SEsHHC9GppppppppKuqmHGQJ1111----1-3332UY435322332J1Qs29GUS78ED6ITWXbSRx****hiZkVXgdIcOtsIcXk2BOTvOgZkNUoPOLRFKeHFGILR8CDIPTAacekPTBJOJCDJC7aKDGC3ISGdROQArQGGFbRCLCD746666543262322222D668GIKMKITaPTFLFEUZQUQVMWZRQPPgXbVXV1-6EE9R------FIFJCKDWYXPdQOWJL-VQYROMPLOPVQTMMYKLLccaHEOgDGCDCFFEGOFCEIDCGLIJGKFJPF-LJMJJNLJLIJK--CB69769MMNNdIiAIA89787643434Qq6GFHNG*GI7AXRbcceNgZSPTTPRJ**Y8Gn4672bGC*FIRFGGGG*PHRUQTMmWod***BBCB11O4II878722212211D21----1-64714421121431121113D243253339H99 cYLO***-***kkkfngreichefogjggcbbfgagbgccaXZfekfecgkjo*dihfbfgkbYXROPFVXRZSUWXIVXVUZYWWUUUcqXgrf*YTSvTmTomw7*************************Z******************************************N**i*WZaql****n**nu***** -------1------1-1----------------------------1------------1-----------1----1-1----111---1----1------------1-11121111------11-11-1-111----------2111---1-1-----1---------1-6211- * d.3.1 Cysteine proteinases
[  27] BB648788A8889A8B8BC9CA69QGGSHNKG6873437A796DGCPF5BadZ5ADAAC8ABCA6138 CZeB*FEJLLKBCDaONLN-LQ77XaLLLLKPRQPQlqqiDmRmr*fiVkgByookYf22**iK*a****MBHIIMKLA4HGN44543TPXS3UBC21-GpHQPpGfCQ221131211111119E9879C686FDVVVZXGGG*A*LVTUSIBDIJEBD987JRBgbjoI8D8AA8AC8998tYwEE855EAi********m******ryjjlr***HLS*jtxWWVVVU**hecebeaZddddcdecXYklbFO9XZBDKCGYXHGTWGJJNQORVVXXXPOOOYMMSSSSORTRRRQGIFGHGHGGGGFGeRQMLHNNNIAekfxdbcghpjVhYIPNMCPTMwDKDHUIO93voLCBBAG7583AC5MIM6ObYYd34225WRxpsTJNcVUUXMLMKLJMJMLl-TPbTbmRga*P3*txz**w***oxdURbMQoeYSXXUceDDDDDDDDQOPBGMaO1111111122-5427714722133111134PRTRCVURGXs****yjdffbhhonpmmpQh*piWWgR7BXVQLLWGGYKSRdJFRJDF6C*H7988888EENKLMHYiHGCKKFRQMJP4IJHFD9GGKJGSJzyKLA37827888743954455559F548JIrqKUMTnQbLQhlomjlWVhbcifcenhcu--4DFFM1--111ZoifIlaQTTPRPSRQQ-SOSSSTSRTPTSVQSQQRPw*uYbWbTRNRTRQTRRRSXUTTV*PMKOMNOG-ZQQRQQOQRPSP--9K79677QkUcAF*PsBAAB7A54545554AXTXgYNKADEOIloomp*zucedgcQlvrD665665669jciphhgdf*plztikPTOURPPR989811JKHHBBNO33332223R3D161-2-1---22----1-82-12227J665565448QHJ JCIJ**a3*TTPaal*x*o*****z**y*p*qvwvor*x*s**ijj*z******ps*nnqpkfUTMQPIUKNUORRSFXRNRTVYVZXak*oxu**dTaYkve*hwBb*********krjultn**m*k***A***bysh*iqztWsiih*Zd*uoer*jmkc*nwe*x*****mVmwi*dclje*qp***wsryy**Z -----------------------1-----------------1111-----------1---------2--1--------1-------1--------------1----------------1-------1-----------------------------------1---1---41-1- * d.108.1 Acyl-CoA N-acyltransferases (Nat)
[  28] -----------------------Ch87K5R9I13C42244444*m2C*6IMEK12-2122----1--9 f**E*CCEDDE969KIIDD-DZ55KYDDDDDGeRSUXdedRub*gbIFIRMKNQRDBI22WYtD*Pl***SE999KB96BUDP37AAAfd*m-h663--A*GfY*c*T*122222211111112FC4IKAAHInF*****XKS*J******VadRT99CGEBw*Zv***m696665685655oWRDE697JPYllololnqRpkppoofncZTapruLTTvLPOIGFHGJ**EHHGHGGEEFHHHGGDGGGBK8A6HH77549DD9AGG8997A6797KMLHFFHGEFEEEDEEFEEEECDCCCDDDEEDCCFCCAA7BACCQzYg*iiinknnaiVdphhMMOJ*UhBDZalaH**wZPRFPKIHCMW77A*a*****CCCCDkr***jXd*****PPNOOPONONc-********k*m6*************p*WsbVczwvwakVMMMMMMMMKUUMO***55555566446A444444644442444445Ld*NEWWTLb*******prqi********W********69****z*ii*****Qi*yfgdZ*Z4555646KJbr**q***jS**P*****9*******n*******c*kGIH9AAAAABABAAAAAAAsuNLeCC*pM****a**c*w***ptu***ox*v*q**--9VUbY------fYbYUbRbddccaacab-deaadafZZadbbYaaZZUbccVZROPgbeheigfefeegehjkYWTYWYaI1eXXXZXWXYZXX--BRCDCCCGGFFLh*T*66664636656546CLKJKMDLHLGj******************421213212Tklo*vxxxx***************QPMP33*E**bdnm66677676D33-------------------------GH8FEBBCBB9*4Q -1--RR2-431111iLMOLJGGILDGFAA5646778A8787997A8LMDFLLGPFGEDCEEE876444284685655155577796966BD7MAE8DBCBEACIIQ1HKW2432233223112233-335F1121411-1431421421221183223G11127-311217-2H23EFDzA9A96*Zf*PtaFAf5777 ----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------6- * c.23.1 CheY-like
[  29] ---2--11565635412511---131121921--1-2------5-214-6763--4-B424121121- 89Q2W7747663838669B-B6229A999997C656879B895F8A957993IIF56711AD56N9KKPJ585555653272721211GHkG1E32111BJ2GAUBP5C11111111211111111123199521ADDEE224T4477633A4122553322372446571213212222128224688348B8888878648979B9CCDD8EA874675678344334BS555555545555555457456553563442377227854444245655445558557778879878755555555555557773337779754CC7876987888D7443A95H5742657627563246455443912662m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af*1*Ti4OOSeb*nhs*ismrqUUNOSQLKIJJIKILKRPOwloxy***pryzsikmJFMEDFEGJIIEGIJDGKLMKGGPFDFz*jbzvsVRZIRddUWd3x*q**********************y******************************************8RZJ*CLFZN****n**SL***** -----4--------1------1--2-----------1-------------------------------------------1---------------------------------4-----------1--------------------------------------------1--- * b.29.1 Concanavalin A-like lectins/glucanases
[  30] GF9787KOVXUUNWNPGHHFHHKJTIINKMDJXbK89EAEDDBIRGQPIPQYUAMJKJKKKIEJ929G aU*MnHDNKLJBBCLILOP-PUCCSORRRRRMTVSVRVaWSgiYVSRIIOMLUVYMDGABVPTCeQXgjfNGKMMIFIICWISEGGKLw*wq8sJJ8--KjVcUec*LZ85557556785555NSQPQXSRXWePostwr6BBePgps*uvrHIRRYRUJLNLfSi***xGLGDHKIVMCJMDJHFEG9AHDRXRZQbZTXPWVVXXXMMLLPWVTQBMFEFDGDBBFABXjCBCDCCBBBCBBBBBD9ABEOG69FJDBEAIHK89JKBEDEBCIHRNMOCDDDGCCIEFOCGLMBLBBBBBBBBB9BCBBKGJEDEGGH9NJEoZSSSRSUUXSZHNNNENIGICPBBKZRJGXUOYVJIEHIBEAKFFIQIeYNNS45556YLUVWQLLQOOOOEEFHEFHGHGT-qhpnipjsQkJ7fYYYgfihfkdeWQfNQNMNUWTUPLKTTTTTTTTXWYQWfaQ33233222232279AB6AB8779976485AFKYCJJGGEJbacYaaYTWWUSSdpeeegOZdcjUUNRDJQTMNOQNFGOSOUIONSPIMNLMCEBDFEBPNNQVNEZYcILgkQnaifhJvovliezVfYZUZagXaCAFCAOKKMRLEJCFDEECCEBADKPNOMPXSSHEXDKJMIMGKKPLIGIIKOLJON2-AMNGM21-222NOKLGPLOSSROUSRQN-PSPOXOQPSOQRTPMOQPOOKOLKGNISGNPROPSTQONUOSMLJJLKJMJH7KGHGHGGFHHHH23EAAA9AADDDCXFXJDHDEDFDFHGIEEFHIDCHEDAJFF9bSPOKNVchRPQLWXIaYYMEFGFDFFEFWPMMDBBCBHKLDKMLTSPRQMNNFFFEB6WVbaYYWU54424444G33----2-2223726---7B751---1CFFIEDABFCUsSa CGMNTY*-jFCEnlktnsiekmlt*unaYiXdhbYWZmbdbecXbXzpjj****ttptedgcXPaTRRHaeTSQdVVNUaQYbaWcNNLw*hnwilbXdSZeW***9s*Z**********************C************w***y****************t*u******ShpW*VXRkj****o**ji***** ---1----------2--------3-----1--------1------------1-1-------------------------------------212-1------1-----------------------1-------------------------------------------9611- * c.68.1 Nucleotide-diphospho-sugar transferases
[  31] 22524126CBCDCCDC8K557522933H6V8-23124-111137235631A8744G46A66C444-32 yu*8*BHGEFHCE6ENNLL-LQ66OMIIJJJIKRSSPTWSMTPjp*vAiiYJjlgEAT--KQPV*Jw**zOjWWWbeXC56EG44333****5pFF1--a*5MI*O*H*44444443343333A7B9BBB7BCDAggfgc--1xENWaPQPEAEBB99BADBAE6MLRhK5868666A7967WQKBAYc5JIQQNQNQRPQJOSSQQQOdaaJXPNOGKTBHNUPSSUSOI*C99787878899987969DDWXG3SZ76MCQac88ZgBCELRGORREIFSRPTQOPQRQSQSWOPNOJHHHJIJLJIHHGQVUDC4VTTPcPAlzLLKLOJJWJMyNGG8ddO*4eM9DKiD8FE5AC4Y72BEIPf38EC5WfOPK-3---9EWVWIBFOLLNJ6799688798E-OOVKKTLTIII1WNNWdcQkkfTVQGN9CABAHOJJBE888888888GAA3ADOG11--------3311321151131111-2229P3C45FBCFTTVUSVSEIJJJJQXHIIJEHULXHDEB23DDMK1P33797HJB34E9I8GI4434554435GFH78BIFCB894A9678-FDG9GEC3FJHRIY*8L4211-321221143431-237452566RPOLB*R4d7LGGMIKBE7DCD5AA7F57P1-2C565------NcJMFQBOOPPPONOPQ-KOMNQKPPNMKNNLOONNKZeZWVEJ2NLGILNLMNMKNPMILWGIEIJML71LKMNNMMFJOMM113235633GIECC4Z4O999CDE3554779A65766677213K*GHJGQOJQKKLMMMTPQIBA9ABA9B8FNLWKKKMIWSLbdLEwtxwwdgdGHGG2-CCHH88AC76645634C2N-11-C-11215-1222544-61---LMOGDXUVXUG*dH 74DG***1uNEFgf*************pnijkks*utgaeahhkcZ****************XZgIQMENOJfLmcPIkgKZWUecPVX*******hdmjf*r*wy4k************************A*****t**w*******x*xv*********************pNs*j*aed*********cy***** -------------1---------------------2-------------------------------------1-------------------11-1---1111------1-----1----1------------111--------------1----------------1-25--- * c.1.8 (Trans)glycosidases
[  32] -------------3--2-12---11--------1---1-------------11---------11--1- 14M-1113444--11----------1------13232231-1--3311--1323211-------13-2351----------4---6--2--1----*---61-46-523--------------5--1-1--------------2-D323--22211--1--121144324------------312----621-4444433415123321-----454---4-31----1-53----------------1---1----------11--------------------1--------------------------2----------1-23-------1-22-11----1-2----1--------11-------32A-92111-----121411-2---------------1-11111112-11-4113--213-2131-13-12-----112222222212222312558ABAAA56em66UT46S543A82Q8d*111411322211455515111122231111116h83333-12351323334322133523442-11211112212376429--2---211--2171624-1----812462223222322-D-1-----1--2111----41--12-2512-233-3--2422125--1-121-------2-51122441211131-512221-1215131111121113312-1----1----------22322--21-111111111111--1-7OG9BKQHK5181---------------13443341---1144342614132222223111-14211--1111111111-2184595C93334332-19*GGA6FD22212221851-----1------------------------------33- JEJN***-*dd*qZwbu*p**********twmw*****z*y**yrs************c***MLJJIHAKMOKHIKMELKKIJIJKGFHNplu*Y*GKJHHGIei*2*************************v******************************************D*****y**n************** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------*91C- * d.211.1 Ankyrin repeat
[  33] --1122647344785474563-2CO35F967A1276648999BIN-5LBP**c199C8EC33346-14 Cav3Q36787A46368844-4H--AE344429EDGF8FAE8FCFDFA46DA8TFQ76C11FGF7V7JYhWA366684322DAA54A64HHeF-L551--6L5BBndOGH122222243333336839573575E3LONXP654X9F9GC8825733412112453bFHQF111311121221DHEBB71566AFCGDIHEIDHKIFEG8C888AHHF5867887EKLJF9Sw5443433343334434664356234634445334435253222546767543433358876777886523325566343354222132329HDAD4444325535D6336788B8E45E5B72CB3763832C76E7455OAQ844313--1CCPNQLDEGEHGG22322223218-OMOHQOMM8G7-EEGBHGAGIJAE8G5A4I7IFJFF86C9999999999B49JCE-1--1111111223-1124233222----15C9A57B986GGGJHHAABBAAAIHIIHEDHLKLLFOK39PPNKLE86UD9FJ6FFH9B8FJ53343334569EIJFQKHBGIE6GEJJJ3hPdPNXvDKPQUU*Y8V7212-3333241633223227216878OI6I9YK69ABNIHJKIANKFH7JDDIAKL1-39B7E--1---EIF9BIAGKKOGJLLMH-JHIIKJKKEOJJJJIHIHLJJJ9E894STNMOPSQQTRPQOMPJGGELHEG5-FFIHLHIEFLLK--17111116665G6f6F2223631653344474244425379BZDCFCGOJHKDFEHCBAD4442445346ENPKGKJLIVOLVYKHFJEJH99B664652N47788BB45524122C33----1---2-1--1111---1----9A3638386B8o3C BC7B***1jCE8KJXNKUONMNOPRQKLLJKHIPLNNQNOLNMKLNVQNNUSYWJMVMJLNNLHJHHI6IKKJDMOOBLPHJLLKHDB9LbKKQQaIIIHDGPSTO1a*s**********************Y******************************************Hozt*ex*cb****Q**Iwr*h*j -------------------------------------1------------------------------------------------------------------------------------------------------------------------------------211-- * b.1.18 E set domains
[  34] MMH5LFD8OQNPMMOEbENNNKCChKMcPJWG88464ACCDB7ACECJ87dRJ4KPMPI9GHF9F-65 788B*KKOPQY7M9UMOKK-KYAAO*KKKKKLhilkVt**JlLl***Nm*wN***GLu44fbeZ*e****aYSTT*gbGCKCX55556555537224---12-1652A26666666777777797758876C7C7gonrp777ojOPPUNNORYLMECCBEANMIJcWUI7D87756E7875xmQRUrt2XMUiililkrsYhkmkgm**jjcfijoSTmtqUTZZbaZY**JQQQPQQOQSQQQQPMOMKKaQNMVZKDJLLSTDDWTFGEMOQJRVUWUYSSTMQQXbbadaZaXXYPNNNMPPPPNNNNRTRONIRRRQdpOZvVYUUWcWNUNgVRRBPOM*IMXIyHgD7utOOBEuS9FUSSmBQOA67DDDCEBDABRM***FGazef*W*******w***-cb*YW*Z***GA**************377w*********GFGGGGGGQNPBHLIs55453333331111221111111114456I37BC6r**********vk**t********i****wj*p3CljkmTgUXve****QZO8KCElQCDBBBABDB9FNDHJ*9TTacIGeWWeDHG88DDHFACBCCNY9PABCE5FEFHCB7A99A98996H86977ifmBW9E8D9vAFEFF7DGFFEFCIGDFHC5-5EFCA------****W*squuosooorq-trrrqrqtnrtoopqpqpo*****QQallkimllklklklkjl*eiejjilP1v***********22C787878ABBBC9up*TTTNPPFJLEESGIQPPPNQ9MENMgL*upv****p**x*X***955559655BaggnjijiilotsqA9FCCCCBCC9999125K66666588887888L7SE9H6C-F9EAEA87787E78GC555U*ufam*knj7G9- 1-12111-1-2-151112-1--111-1111212212-222-11-1-131-1-1-1-121221--2---111-3--1--1123312112-33-1233231-14221---12811451-1--223222-424N2-21712-----1-111--12-3-2-3E-112E2232-2H2363424--11-13D13D1--1-71261 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.58.1 MetI-like
[  35] 541126464334538456444244MHIH6AEI43142-677565D58a27A892C7A6BA45425246 BQW8KD9AAAC888LEECC-CK99JHDDDDDEJHGIJHHE9DEFK98CK9A5EHG7EE46CBM7RCIVQLD6887977436273CE77DDC91D55511EKGJFWCKKH22222222252222H33186631394EGGFL432KCPPLBKJG8ADCDC8899FD9IHINN5947546A5656AAE653379PGacdbgaakVgbdecXFIKKQIbedDGGoGJOBA9AB9kO8889867577998874565479B5BE5698B8CAAA96A66797989998645855666667866667788767678767899666A998DWSi*aZZaacZVejN9igN565eOJ66GGLODfjILEEQIDB98CE775TBHXUUN45547DBeeiA9EQaLMZ7777777677D-LLVKNEOPCF84RRS*YbVidYKJk8KEGBC8GFECHP865666666GIHB8qcm332353342225324422412222222232FFIDBJIHFIVWWVXTzPNPNOOZaWVVYHTSadJTLQ44QNVXMdKIfEFZICLUPGDFKkW557666578A9LQaPHDQ9NaLooRPV4bWcUMZVHPWYQU*dCBXFDC3CDAC8B6C7656666HVFG454tc8QPLYPQR8ozzyxccbupsognXqpsg3-7C9HE211222OdloFSLEFFCFDFDHF-FFDGFCCGEGFFGEFEGFC8A9ghCAGJJGCHIHGHGGEJDCHLCECEEDG52MFGGHFHGGJGF246D44444DCED9BnLq888655433345445BBAFC87779FMUWUSakivZUTUYaxrv534346343KJokinmnpmZcdwxTTjjlljPXXAA9A32epccGHOO78788777O6733432-3345534223343325333E7GGJABDAA2K7G L*66bZp2*VfKmhcduaWYaZclbjaZZOQNOZcVVVOWSYXROTORTZikveeXdUJdZYLLJLNNBFMJNILSMAMMLKKIKKLOQYmXuzkvQMLGPUMXTm8p************************Q******************************************Jl*Q*YPYjNst**a**iszt**Y -----------------------1--1-----1----1---1---------------------1----------------------------------1--1-------1--1-----------------111----------12--1----------------------3---- * d.92.1 Metalloproteases ("zincins"), catalytic domain
[  36] 11111111111111111111121EuCDQAjWa12G21244445ss4W*9YkRX11112421---1178 Z**7*99CCDD968DLMEF-ES66MSEEEEEDZLMNYahaFiTvaPCDFMHCGMO7A922ORj9yTX***W9999DAA9DTDJ55ABAtt*m2*98822A*EXR*z*jz122222222212124CA8GG8BLNcA*****REK*8*p**llPPPII859CCBbmLn***f7A67666A6786cQJ78686KObhhpgpnnnUolqwwpbZYWVZorxJSQmLUNHEGEEF**CFFFFFFDFFEFFFFEEDFAD7A8IG86759CB67HHA969B5799DDBCBBCEDD89999B99999A99999AA9BA99B9D775A9BAFxba*aaZhhgeedYSpjiJQTLjVZBDSTbU9wshTLFCKCDCAHF688vWl*vvoAABBBUZ***dQT**pv*JJIKIJHIIIS-********Qrk6flkopgbt*ngfimWQcRMXgdhePeMFFFFFFFFJNNGI*oq5555544565j*557756765655654455HTgGDKLKFT*qww*yqaceZpo**jiklNgx**py**38nqg*rwVW**y*vLbjrTWPQmN5657765IGThy*n**iTR*mF*****6*******c*******T*b9EB7777756464454555bbCFWFFeVKphvsPrbUkghmiRgfjkicijenfvs3-8LQSV322333USSQOSLSTTVSWWWRS-TURSTUURRSTUSPRSRRRWVVSRLJHUSSQTUTSSUUSUTQUcQOMPOOSE2TNQPPTRMPPPO119IABAAAFGFFMX*Mq88997736586667BKLJHLBJGLDad****x***m********655536645MUbXnghgihgnlqruruqurpdfiEFDF34*9**UYnm45455445A33-------------------1-----AF9B9B89BAA*6K 7A47RSG1VSB7DCnSUZWOQQPROPMFFEGHGFEFFKHJGHJDHFXULMVVRbPOKKJLLLDCBBA98EBACDDBB7ABBABBGC877IQFUIPGLJJHMHEQRX4QinkVWROUaKHOJMRJbqPfG**Q2mVkKKKLTIMUJEMNIJOHDaKTNMaFQXHMGq58AGOGDOFAKMI*CDDEI*Wf*ZnmQJlHGGM ---2---------------2---------------222-3------------------------------------------------------------------------------1---------------------------------------------1-----1116- * d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
[  37] --------12111221-1--1-------------1-----------1--------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------1---------------------------------------------------------1----------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---1-------------------------------------------------------------------------- 6757KER-R97BQNWVVWRUWVPSWNcQTQPQZKMMLUGPJLRPQQPbQTeYhcPYWVUZUVJGTHFKENQOQJLOPFKQHRTPNQHFESgiVWikGIGNEfI***5LN8*************************************************************w**jB89At765CFi*y*Y*a8AXPQO4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.37.1 beta-beta-alpha zinc fingers
[  38] BBADACFGFFFFFFGGAEDDEDDGFEFEHGFDFFGFDEEEEFFDFDHGFIMKKEEGFFJGFDDCAACC LLOENHKHIIIGJFEJKIJ-IIDDLIIIIIIIHHHHLHIIFJIIJGHFHFFEHGIHEICBHGKHMHKMOMFGHIIJJIEBEHIHGHKLLKKJFKFFC89HKILKMIMFKCCCCCCCCCCAABBFIHGIHJHHJIJPPQPPDEFOJINQJMMIHHIIIFFFGFJKJIKKNLFGEEGFFGFDEGIIHJJLLGIIKKKJJKJKKJJKJJJKLLJJKKJJKLJIHKIHKMMLLLKSBIHIHHHFGHGHIGFHGHEHIEECGGCHGEDHHEEHHEFDDHAHGIGFFFGGGHIIEFFGGGEGGFEDDEEEFEFEGFDFJGGFFHIFGFJULQSOOOOOMPMNLNMNNKLLLJJNEFKIJNKNMOPMPRKMKKKMMEINLLJIGGKGFFHEIKKKNJJGJJJKHHIIIHIHIIIJ3PQPQQOQRKOIGIKKKLNMKLMMLJLJGLLLHJJKJLKJJJJJJJJJILKJJPKMBBADBCCCAAAACDDDCDFBCDDDCCABCAGGIGENNMMMMOORQPRQPQPLLOSRRRROQRPONPNLDGNTLNMMJKIHMLPMJLNKQQSMLIIJJJJJJLJLLOPOTNONPPLORNNNJQSQOOQPOOKMLKSRLKIIHJHJJKIKIFIHFEHFFFIHEIGIJRRRNNTPNQQQURSRSSRTUUURUSSSRTTF2JLMNMFCBDDEQQPQPSPQRRRPRRRQS-SSMRTRRRSRRQRPQQRQRSSSRQQTRSSSSQQSQQRTRTRSRSPQNPPQPOBQPQQQRSPQQRQFFOLIIIJJKLLMRMVNRQPQQNPIPPOMNMNPMMMKLKMKLKNNQQRQTMNQPRSSRQOQPOGHHGIGHGPRSSTTTTUTTURVTMNMNNNNMMLJJJJDDMLLLJJLKIIIIIJIJGDE66666-667768566656F567777HEIFGIHIJJGKGJ PPDHabe6*lUIZadUWfYUWWVYVVZZXSWWXTWRQXUTTVWYXWYaWYZWcUWVabaVUYWTXWWWKRWUVRVbcNcZVQSTTSVVYUweWdeiYVXWUkXmywFa*f**********************C************l*xvw**s*x****n**t*****y**y**fbbfi*jnhaf****Y**ihvvknY ---11------------------------1-------1-1-----------------------------------------------------------------------------------------1----------------------------------------213-- * d.14.1 Ribosomal protein S5 domain 2-like
[  39] ---6-3-2-------1----21-45BA8-429112-11--11-26-2914314121---1---1-1-2 6Lb321------1-12-11-131112211211321222223221E2-11--2-11-------4261-2-11-11122212D7-2-G13654-1633--183353815751111111-------13223232332378846444494--122731--11112--311344-11111-1211----1111113-222223-13-121-1135212111224112-121111182-222211213112222111121-2221-12143--44--1---------11111--11111111111--1-1-32211-1111111111-3877F45468354412444411113J31B129-ML482728N3--3111-5EM64441--1141ORi324EMPJO------------KIOGI5EZ111-34469768ED68551128438B78723111111112551-NG7111-1------3---------2--1---1--6451-3316134235722224433242214236767711333J4B55232P2-1183342C7232-212BEB3F95IKL5LLIBaRSSZ2***z***8N****IH8C47CC666AA5A3831111--5957811GD168494325TSUUT4QiUYWWWRmmY*Y---54BD------6515C-1AAABAB8CB9-AA99899AB9ABA99A99511-551-2967698888777886967739999--533323333222----------121G19339898B8757976778111121--22-276979CBHB594CCBAC---------27ECLEDDDDAKCKI-221-11-1--34313H3664422--------111-------11----1-111-12---11-221-12--4L21 12-2F6U-O6BD57A3785F967B6849654265548725541J64AB89CAB9969969GA6956451635345353263335657427H9799C46412579D61G7E*************************************************f**j**x*****k**G6246j63864mDIMCMD2AIEBO8 ------------------------------------1--------------1------------------------------------------------------------------------------------------1---------------------------1---- * a.138.1 Multiheme cytochromes
[  40] ---11-------1----1------1--22--12--21-212---2--122G231-1131-13----22 1-3-2-1----211-22-----1111-----1------1------1---11---1-------1-4-26531----21--22-------2311-1-----14241415-3-111111--1---------23-1-2-2--2----2-438344311112-4222-1233142-1---1-2----1-111--1---4444423445543341-11--44513-111344233331---2-1--1111--1-11114--1--1--2111-----111--1111--112-------112-21-2111-2-1---1-1-22-1-4-2118147111443224212331211232-1142-11231-1--1-2311-21-2A4664-2---14424--21123311111111111-13224313333-311524295462-153466-3133255222222221-1-1331---------1-----1-13-1-1-----2-23521111-111131311111111133212111-2342--11311422343--11--131712-------1-312246813-131643361121644213--1-5515-41231311311-1------2433-111-25133-6B3-121122412121115113--11---------1-----------------------1-----------1-1-2-11--2------1-1-------------113--------------3-11---11-1-721---1--------2--33--31-12--41-21232--2112-421-11-11111-11-111111-1--186546436542222--N6--1311-------1--1131---41------------5---11--1----1--111 eZVc***-***Rsn*ZXjWYaaXfaXYWWZWbcZcXUXSUWWXVSUXcbbZXZaXUaZTVTTVOUSSLKROLOTQSTFOQMPPUKOTOOcnTXYhYTWQRLjW***8*************************g******************************************J****knmtq****c********* -------------------1---------------1------------1-----------1--------------------------------1---------------------------------1-------1----------------------------------2---- * a.39.1 EF-hand
[  41] ---------------------------------1--1---221-------89------1--1------ --2-3---------------------------------------1----1---1----------1-1121----------26------4391-7336--4G7126G7-1-11--11-------923221123441----1---9-914543111------------2173-----1-----------------43434743-3224321---2-225---2---HQSPL7----------------------211-------144----11--1-1111112323---1111111111-3333334333332-11---1111-2-71675877827111332121652-4--21-126-1326-------21--7-11-----1--4---------2------------11112121---------2--------------------1-------------1-2--------------------------1-------------1111111----1111------111---1----81-5---1--2-----11---11-------1--2-21------1-----1-112-1------6C-221----------3----------1--1111-115-111111111131111-162113--1--------------3---33-1---21-31114--1213-31--112--------27--2113222131-2-A9BB69A2-156646533345-----1--1211---6-1-----------1-----------512111-18247-68772113----------2223-----31122--22323222------141168XR--------F-11-1----1--2-----------------1--------12 IB66***-***abdpEEEDHDHJICEEHHEDGFGADDFECBCEDDHDCGFGHKDFGJHGIIJCHKBD93HHAWMaFF8EFBiiPQzDDDQbKETlSGDGDPIEaWX8*************************r******************************************7**t*NPM*k****B**dv***** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------4---- * c.10.2 L domain-like
[  42] 557784BEQLMSCLMDEIFFACBBKBAHEN98DQHEBDCB78CAK3XOJGXdb5AM9BDHFCC98296 MW*IfF9DCCK997NQRGG-GRBBKPFGGGFFVQRPOLRULqcscLQJBQSCRLOPKE44cUJFeMeRPVK989977645D7OGHAGFqmkn7oFG4--LcPSKogkMY44555545554444BMKTRfIPRWeM*****455*M*tn*rrqJNOORWIJTOTcTo***sCIEJHDBOJKDDFHGCFKLFEAHLJMJNIINHIKNLLIDZPPGMHIXGFEDAGI666675NaCGGGGGIHHHHGGHGHEDD94B79AD8697DJKCCHH7HBA87DB8CCD8988A99D8AB9AC97985555555555555GFDBBDDDCCLG4cRKJKGJKFFHHIDJIIQFFGBS9CMIKKIJINHXCPADKA6DLADEMOfOJLY44433PTfbYLFJJQIMV88CC8BC9B9I1ib*qgtkqNUF4gRRXVZXRcRbbZMJEEDIFLHMNFKBOOOOOOOOfbaaViZh22--111---338866B899798883142CDKSA9FRRKXpggeoqfZaaaZY**klkjUiul*ZOOL8JMNGSKMIEAJLLJ8CERQMCPLFCB8BBBBQLYgZZEobRMVojPnkffcPfkjjfXuPcjeihlpfhHKFJBBA77B8FED9EABABLLFHHWRLNDRXJH8R9NCDFDEBCHCCDCEDDGADA1-7cRHN11-111HLJNHNKIKNLIKMIJH-KJIIMLIMKKKILHHIHHJIPNJGTSHMLJMLMLMNJMPMPONRHHGGEFGI1FBB9DDDBBCEC4477BCBBBBGEETGbNJJMIHEG9BA9DE98FEBBGCCE898QRSQTRPSSJKOPJPKNSQGCDBCDCCCENLLFHGGHGNJHLOEHONONMKJKEEEE44nFNMIIII22223222A18--11---1-11-----1---11---QIMGIIIJHHUtRV 35DCYWW-YEGBKRTJLPNQZWTcecXIJILFIHHLIOONLMMIHIUSOPXZeoVPSOOSLNHFEDGF7GFDEEEII9FICFEDHHKIILaKLORLKHJZFVJja*2a*j******ogdUeatd**a*f***4***YeWb*Xk*lRiZUX*VO*dwdsr***j*****ky*****J**b*aYZsq****Q**RUq*m*p -------------------1---3-----1--------22-----------------------------------------1------------------------------------------------------1----1----------------------------32--- * c.87.1 UDP-Glycosyltransferase/glycogen phosphorylase
[  43] 78A494CBCCCCCFEDB8AH97A7FDFFDEFA76975855665756B67BJKC7DEDJHHE7879134 IMR6aGBIGGIDDBKJHKK-KO99LQJJIJKFTPPSRbYY9TNTKLL8HKKHNNOEBL33WTGGUJhcbUJEFEEGEEH8FHC88CAANNLP4QBA2-1AK8DBRCOEI33333333555555AEF9EEHDCKEH9AAHI566LIWHMRECEBEJJDFEABCOFHIWOXHADA8976D9899JFG8ABBADFNQQYPXVUWIYTTUXVQMKKLJTXUFCENIMMQMMMMMQXFJJIIGIHIJJJJIIIIHJJKNLBQQDCKGJWVAAMPKGGFDDOTVPOPRJHIPLKGIFIIHGJHGFFEFFFHFGEFEFGNNMOOHKKKT6DAVaGJGKMOLRIREOFEEIJEOBEG8IKKABDBDBB9DA88A9D869IB7GKDDG22423KGTMXKBBIIKKJFFEGEFFEFEL-KJJJNSJKFRE4UIJPPOQTROPQGIFHCHKIDDCDGGFBBBBBBBBDHGABBFG1112111211112244243212222114168D9D8FLMJNTRSTSTOKMNLRRUXNKORKSUPZGLLM6AIJLHKJJHIPOJPICGMBGBEQC999ABBA9EFLDGIEKACBFB9DCAAF6CIDDFFDIHDDJDRbBJA5486ECCCBA887A6897788A9ELMRONJLHCCFGVGKIIKJMGLJIMEIIGLFK2-7GEDE221223VVQNPVRTUVTTTTWVS-UTTVUUVUTUWTVRSTRQVSYWPSJJMZTXTWYXWWUXVYUUYRPRPQQSRF1RPPOQQPOQQRQ343DBDCDBFFHGEFPJOEEFGFH8CBBCBBCIKJLLKEFAFBNBTUTWMQMVKMPNNJVbUBCBBACCACFGHIOJJJJJORUOPOLJKJKIKJJ7787A7FJFFCCFE5855555585D8B847-B798D846778CA67B5555DA877C997BKD8 OONOjWV-*niOcgogkrolstnvsvtacfiihfggWjcegegfcgijjo****ejnljmohXYVTVWEUZTXRYdbQbcTVUUVWgYbc*gkkjwabfYY*Y***Cc*o*******wmmfkws**r*t***7***bjpj*sv*mVrnoS*ke*z*w**c**ouflj*dg*g*pdi**p*rrr******t********* --12----------11---4---1-----1-----222-3-------------------------------1--------------------1-1-------1-----------------------1------------------------------11-1---1-----3---- * c.108.1 HAD-like
[  44] 11111111111111211222112214422211-21222232222112113233112-22221321--- 67E2733334432365767-682266666666766665874635C75676637765452298B56389A8211112111111634444437325333113334442433222222222222223222222222326555434362321312322433222222322222222131222232233332323446555555455545554758877556444464444444454344444444444443444445233443434423445424332343344434343333333333333344444443334342223333334233323333333232222232224322251-535552244442333221275A44433444544444544343444444444443414444545445435558656655574456665765556774444444433444854333233332222322333333233233333655553333455545543444555455554556447673355646555557654545543374534444435536446523355645A962767577654A98AB54522222222223-1222212-2222444795464666675666566855686888889313653722122288886887C77798687-68788887677898878877988756787777777777787779777788742756666556565332633333666655866555555766556555344454465654668666578665648753334333333866658558765556557576555444433522123223332322352232323-323233333332233333323222222222423 8847**W-I594Zc*PTMNRORSQVROWWSSQTONMIKKPGOQTRRRJSSRQWNMNVMQMQNQLMEIG8OKELEPIHCKLEMMMMKRRNUkTTYZeXXYWMXX***4*XJ**********************U*****************************************vHQKG*ECAKF****M*c47AJDDD 1-111--------------1-----1----1-111211-1-------------------------------------------------------------------------------------------------1-111------------222-------------2---- * g.39.1 Glucocorticoid receptor-like (DNA-binding domain)
[  45] 11222-12444444342223222134433322112111111111212112333111111112222-24 BDO4A23422243465455-55555665565556665575466645434443556234334445547986411111113322647756BA8C27775--46359D8A87322222234344445544544434B4877DE44366968A7766666665666567C98A8554445455456C994433166766666667866667A65978666756797554444457843333333333333343333334344333334444444423343333333343333333333333334444444444444423333333383484545556555595666555847236546668865557776666313A8R9AAB67668B9DBEC96B99A777777777778-BBCBCBB96D72E887EEBECC697789A646A9995677777777769987D7733333333222233345444334433332265B6463335999A8967888BB89AAAAAABC89887438777566487857468849767655555557798D6994435775BA6673ABC7C7878HIEHPP78255534444655455555445554499666969797857AAAA9A89999888898B3-5A89B12-22288797667777888878-77877787777878878877779866579777777777777776667546673777777777777347A43422666689A5544455646664555577777786766766556555544545555---------55666777776766699A7877777555522C4AAAAAA54465465663-------------------------34532232228ID6 743344*1SBB-CDE74743656565667555545436563656553446687G4644463575435435435444444411244688834441353323263DDD2Q*-*****************************************************************AHIG*GC9ICQNUW5LMr*****n ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * b.36.1 PDZ domain-like
[  46] 334---133222333--71121117--91A42--45521-112B*17r13**Q2--1332-1-14-2- NEo2*-24343121B5555-5533B7545557898AEBKF6HDXCJG4AC72AG9-2B11JJ99TEKu**963335GH4-355113-1*y**1W881--Is3HN*Xi5r--------------232-521-2262CEEBD21-e2A773998331222252236177BLB2233222333326F778KM2547A9B9BCCC4AFAGEE5ICB77A9J4657345EDEBD5M*1443133133444333-112B63343334474322882362224253337ACA611DDDCBEFCDFF68878457667864883327774M58955556566477k6555jlJV7o41635528AF56372--33-S11-81VAAB311111453412113226222212222123-4454364576218558877AC84731345453255477C2222222223233-13---1-111----1212224311221-1--1-DD2533324CBCDECD9997BBCBEEGD8CHGH2956-1678638326424731291321232-2132212245349255242145111-58942392373B7bb262221212212222-11-1122-3351-72371*F2L38C77776756655E72B47D--34432---1-1374432158B3533544-74543334457335658534875786429-2-2-123111122411143441-488867768966-1-4-----23-143Z35636223311--341-43623352223r54572458123123676----------5779AABBA894CEABPOMNKMML8989-122QR88HC-111-1212-2--------2--Y-111-3--6-11-3-473I8FDK1rP9 WKCHpp*1xGQDRSSeYvZrklV*rzqOOIIOIJINMJMHJIHGHKZadn****jihfUXVVHDEDHK9F7BJEHFI9HGFBAEEJIFGNaUYSbcCFDEFbKeVY7X*q**********************T*********************************y**x*****Eb*O*GHIVZ****k**cjjughm ---1-1-1------2----1---11--------------------------------------------1----------1----------1--11------1111-1-------1-------1-----1111--1------1-1----------------1-1----2-1-34- * b.18.1 Galactose-binding domain-like
[  47] BB67A76A999998EA88688B75D67AA7RB3275544445445374357A58EDIHHDD824E237 EQ*9NH9FDDE959HIIFE-LI88GVFFFFFCGIIIDQSS6E9BECEC9983JGAHCH22KHF9OFWMNOC6444766G9ABO53A43DEGI5J99A339LCQeWDRIM2333333333333397546664677AKMMGF222MMHGEBGED688A7775688A7IHIJB655556555555VGNCCDDBGFUTWVWXYXWUZaYXaYoUXXPXVXeSPXajMMPOOOPLzSPLLLJLLMMMMMLNLXLMSQNAGAFKCD9C7CD99IG8A9DGCA9C8987566D9ABBBBBBBABBB5555555555555CBBFD89BBDCiPMUVXTVbRVLVKG*NNRNPSPaHHDPJAC5QMBCD79f9DINKACGFt3NRTTP56555AAmdkEBGNMLPGDFGHFEEGGEY-IGXHESFYPdG3qXXYRSUUXaYVTHLHMHVWNINLPVdDDDDDDDDRKKFDBLH331334441133333333333333334244JNUKESieQWhffdghJOPPKYYXbSTSTELoYZcfig46PRIEDaJMiMeHfUAG87776GB6668676988DGBGFM9A5AD8ALA9A2D7D7869B8DDFBTU9F9DB75CBABE9565555655978BA55LEAKCFVMUVLQOONNKPXNNNGaLTUGRX21ABFAA542666MKfQKLNSVVNSOPORQ-TORRTQPSQRUQQQQSQQQbgdRPGHLIJJIHFIHHHGIIIIHWOHLMMMNF4KIHIJHHEGHII444O9BABBHIKH89NPWAB9F8F7ABAAAA9F99A8959697BCVVTVJYRUEMWOQETNS7672486569LKJZFHGGGSNLJJMNOMOMPGIG898933AIAA889977787989M1A41615-5343722444233135222CFFGDFKHBGEFEJ 5556LRS-*ZNEKORUWwjaYXXpXoZSTJOPPXXURTSTPTSKMKUNYfolxooqnSPPOROPQFNRELHHTIPHFBGJMMNMRPACASfKWWWSNILIEDJbTW1Vkd*******tlkpwzq**s*n***4***fvsl*ov*ig*qoh*hj*tx*p*o**l*m***qv*fy*ZFTVK*EFEITldt*gnpJHlcqea ----------------------------------------------------------------1---------1--1--1-----------------1------11--1--1---------1----------1-------------------1-------------1---1--- * c.56.5 Zn-dependent exopeptidases
[  48] ---1---1----11B21-1--1-1-----------1-------1---1--1---1------------- ----1--1----1--1113-31111133333-1---1-2-11---------------1--12--1112-----------------1---111-1------1---2----1-----------------------------------12-------11----------1111-----------------1----1--------1---1111111111--112----111111---111111111111-1------------------------------1---------1------------------------2------------1---------------1---1-2----1-1-------1---------1--------------1-------------------1-------------1----1--11---1---1-1--------------------2-------111---1------------------1----2-1---21-1--------111-------1-----------1--11-1----1-2-----------12-1----------1-1--------1------------------11122-------------111--1--1------------1--1----2--------1----------1------1-------------1----------------1-1-------1---------2-1----------1---1---2----1-1---11----------1-------------------1--1--1----1-----1------------1---11111-11------------------12---------------------------------1----1------1---------- RLPS***-**gMgh*jYaZZXZZaYTacaSYTWaXcSWbZXWWWYYccabcaefWYaXWXZabOTQTRANXRTNLUWKTUVOOQJNWWad*fYnfraVVTTfa***A*************************g******************************************I*qh*dXVsm****X**Vcw***z --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.15.1 Ubiquitin-like
[  49] 66335444555555486544675889985C596368A6A7A8BBE9A75BA993769789A4434213 KUN6*DATOOP846RIDFF-FV22HgFFFFFAWFIMzdlnDmq*otZ4TZVElkm77K--vpPG*a****WTIJIeeVE7qWD35522SLQH2D872114oAJ9WKl7L22222222222222853IHFECQe66FKLAA4BDn6jBDUAEY4499331131991ERYe922-212122322ED933EE4eIMjmmjmfgoXfvmakgWUXaOUbdoFNLPNHGcUSXaQVqEOHHHFGIHILMNFHB88MKwMQ7SXBLMHQbhQMbeKMEXZDXVbXNQVTRQPNKQQOTRTQVRRTRTYZPPXaTOOSOPMPIFISLQNNjIhtfYYegYZabRPr*rJFKGeDFJ76gvAAcgobGCPHARHOOJ379B5B*ZcT4aQ5qQHeScPGEKPGCNEDCCCCEDCEc-YTUNYnZVMxO6*Zbkuuv****qNTPJVONcFMGCNSOEEEEEEEENQMBBUUg555555554444749935D764663G3FF3DPQN4IMHBTYfjsjaXHGFBYZcmaMPNETftuKMTS14QJNIIOPDoSkIqdBDE8799CEEFBDB7AIDEO7BKTKE9DGADNHBFF8HULYCAX7LEGDHPOB8844341412511411111114654BCANSXOIHJCNBKEOghUIHCMCILBLEJI9J--8L79K------YggtEaSXplaWgZjbX4iXWdWliaWkpggVaVXaTgoegbx*sUVPORRTQVRRRWPNUvNLXRQSSI1cVVZXWXRVZVZ--eAABA8ADFDE22VKbCBCJCFFFCACUHMAB7BCFC9858XTMMSVSYNVDXVSPBWTK5444454445LOPWOYNRYaUHTVOBMKKKMGHISEEG2-N8CBDDCA---21221G3J----3-11--2-----11--1----7MC866C8765W59 2122211-721123112323332112443211133322322224222421232312332323311112121121311-1222231211125323343342122223126-Plups*dPQNKTaR**HrP**l8*c*IUNKbQUiXEUSNOVIL*SZRQl69BOHABAM9BaCI94321-F---32835D2732253145 -21------2-1-113-----1---21111-1121-----2222231-----23--11-22----------------23---2232312--111-1-32223131231312321133--2311--25122223-2321-2132123222-1-3-1223----1-1-3---1---- * a.35.1 lambda repressor-like DNA-binding domains
[  50] CCC9DBDFHIIHHHEFDBCCCBBBCEFD9ACCCABBDABBBBCBACBC9DFFEAHFDJIJFCBCB9BB GHGGKDDEDDDFFEEEEEE-EGDDFDFFFFFFEFEEGGKLDDDGDGFEFDEDHFIHGFCCHHHDFDHHIGCDCDDDDDDCEGGHHFFGJKGGCGEFE69FEEDEEEGGFFEEEEEEEEEEEEEGDCDDCDDDDGDHIIIHFFEKGLLIIHHHGGIHFGFEFGIFIGJHHJGGGGFGGGFGGGGJFHHGFGHIIPPPOOOPQMPQQPPQLIJJKJPPPIGHJGIKIJJIHHKMIJJJJJJJJJJJJJHIHHJJJEJFHJFJFFENOIIHHGGGFHGGGHGGGGFFFHGGEFFEEDEEEFEHHGGGHGGHGGGIGIHFFGHHHEGLELJLLLLPKMGMHHKHHGGGFOGHFGHEGFFHGHIGGGEHGHHIGIFHFEJEEEEABACBFDHGEDDEEFEGECCCCCCCBCCD5HGGGGGGGCGFDGEEGIHEFHFFEFFEECFEEDECEDDEFFFFFFFFFDDEDGEGCBECCBBBCBBBAABBCACAABAABCBCEDDCEDCFHFGEGFFFIFEDDDDEFGFDDDDDDFEDFEFHDEEFDEFDFEDDDHFEFGGGHEFFGEDCCDCCHEEEFFKHFEKFFFGFGEEGEJIKIIHVHJIIGIGJGLGDACGCBCBADDDDDDDDCCCEFGEJJIJEIFIJJHHHHGGFFEEFEDDEGDGFEFIG6FFHFIEDCFFFJIJGKJGJJJHJKKKJJ-JJJJKKJJJJJKJJJJJJKMLLHIHHIJIIIIJJIIIIIJIIIJIJHHHHJFEIIIIIIIIIIIIEEHIEEEEEIHIHGFJGKHHHIHIHIHIHHIHIHHHHHIHFHIGFFFIFFIFHFFFFGEHHJHGHGHHHHGGHGHKHHHHHIHHHGHHHHGHIGGHGGGGFFGFIIKKJJB99A9AAAGHHDDCCD-HDFEEFEDDDCGECEFCCCFGIGFFFFFFCJGG QQKKcYP1*MMHMLRPPUSTYWTUZVVVTTTSTVVRSTPRPQTRURRURTWWVXWTXmRPRQPPPNPPGQPNTOQSRHUVOMPRTRQORRhPPRQRNOMOMVSTYbASomsfvcihqXUSUPbV*zRyT**i8tn*RZVUsWbnYPXWUSgQRvZicXeSg*QWUZVcSWzXnZVRSUS*WRWQSjZx*WtcZShkabS -----------------------1--------------------------------------------------------------------------------------------------------------------------------------------------21--- * d.104.1 Class II aaRS and biotin synthetases
[  51] GGEEECFGDFFEEEFFFFGGHHGFFEFHDHEGGEDGCFEDEEFDDFCDEEJGFDEGEECDDEEGFBIH FGGFIGFGHHJGFGFEGFF-FEEEFHFFFFFDJDDDLGGJEMJIGIKDDIHFGKKHEGHHOIIHIGIFKJGAEDDDCDFHIHHLIIGGKIIFDFFF949EJGIFLEGEG8AAAAAA898AAAABDEGDDDCEDCDHHHGHEDFHGHFEGDDFFCFFEGFEEEEEDGFEFFGGGDEDEHDEDDKLLIIHFCGIFIIIIIHJIGKJIJJJHIHHEHKJIGFHKHEFFFFFGGJMEFFFFFFFFGFFFFFIFFGGGGFEDDECDFDHIDDEEECEHFDJFGCCCBADBDCCCDDDDDECCCDDDDDDDDEDEDDDDECEEDCCCBHIGFIIIIHHHGFIGFFGFDFFFIGGDDFDHGGHHKFDEIDFEFFEHDEIHEHHGGFGHGGIHIPKJHHHJHIJKGGGGGGGGGGH5EEGEHHGIIHIBHEEEFEDJGGCCGHIIGKJMKJJJJIKIIIIIIIIGIHIJIIHJIEGFFFFFFCADCBDADDCDCCCCEDFDGIHFIFFEEDFIHIHIIHHJJHGGIGJJJJFHKHGEHEHFEFFJDEEEDEFFFEEEEFIFFFHHGGHGGHHEDFHGEIONIIJHGHJJFFIFFHGIGFHIIGFHHJPIKFGGHFFFFGGFFEFFFGGFFEFJJIGGIIHHFFFCIIEHFEEEGIGJHHEFHFHEIIE7DEGFFD8BCCCKIIHJIGIGGJIHGHHG-HJLIHHHIGIHIJGGIGGJJHIHJILHKKKKKKKKKLKKKKKKHIIFIIHHGEIHGHHHHHHHHHCCFJEEEEEGGGFEGJHHGFDFDCCGEBECDDCFFFGFGEHIGEGGGHGGHFEGEEEFHFFHEDDCDDDDDEEFFOGHHHHJJHIGHFFGFHFEFFEEEEFFHFHHEEKHAAACEDDDHCCBBBBC-FCCDECCDEDDCDDDFCCCFFEHGGFGHFFJHH NQFGQPQ-*MJFHHNMPWNUNQSRPTVUWUUXXXSSRSPPPPQSNQORQRSYcfRPRVMMQQOQOOKSGROOPQRYRDSSOOOQPPORSNZJPVNYIKJJKaMYcZCSrW*dzabkpWRVSUcS*pRmU**j8kf*RTQUiOYjVLRPTKWQQvQcYWeX**OcgWMjPU*giSWTRVR*QTRNRjmy*SnhRYkYebZ ----11-------------2---21----------11-------------------------------------------------------------------------------------------------------------------------------------4---- * c.26.1 Nucleotidylyl transferase
[  52] --1------------1--21111----23--1---11---1--21111-----1-11211--12---- SfzD*GILKKLEDCORSQR-Qd55TuPQPPPK*jommy**J*o*lxIHHWVRYgfGEK22*ozI*Y****VDBBBQBC6Q*dO35578dfbU1V66C117Y9MH*C*Do222222222222223975768BH759cfhplRGQzGnRdQMLKHGDFFDDIIHKMEadhlE8D88878B7887RSGDD344OJSjjkjkfjlRkemmmjVUTRMSintELLmKHHFCCDDE*xEFFFEFFEFEFFFFFDGHIBJ7A6FG77758899AHH8987969B8FHGFCCFDEDBBBBBBCBBBB9N88I999AC9C9EBC997BACC8fUbpXYXbbbbVZQOjcaDGFCcQJDDYLWE6*yOGKD9DDEB7GA469W7ObKLU99999SU*csQINWXWbbLMKNLMLJJIV1bdicnvfmS*O4srskvn***xppQVJMFSRVZTYZLPVHHHHHHHHKLHCFWOI222222222233435534333344322225HXsH7RaXOZzu***ysiiiUqq**urtsOr*z*s***47hqvjkcQO*ddf*GSiXJNEOPH3433333D8CVXaLMN756E56EB77C2HDFDCENGEOMNNWWDGZCD98777777444544444ML9EQDCZUFQQOfITMDcSZbXPXdaYWWbcZjXnn113AF8C111111fRLPPYfcfgbdaZbcd-fhefcWYbeegagXYaXXVhilQViyIcZedfegecfddgcdbtUQNVUXUP3iWXVXWWUVXWX22SKBCA9BADA9CLgLV777667465455459JHGGI9GB9CMOyyx*n*z*elpqmTean4323243337MYadTUUUUeigehhhXTdTTQRT987822H3GGDDCC1111111161411211-11112111112121111114875555545Aq5F -----21---1--2---1--1111-111-1111---1-------------1----1--1--------1------11-----------------------1-1------3--2---2--1---11-1-333C3-224-1--1--1----1---1---113----2-311121-15-2-1----1-2311L-1-21H4--- --------------1-----------------------------------------------------------------1----------------------------------------1----1---------------------------------1-------------- * a.4.6 C-terminal effector domain of the bipartite response regulators
[  53] ------------------------22212113111---1211122121-2224-------------11 1111113111121211133-31111233233111122122111---11111-211111111111-12111-11111111111-11111111112211--111111212111111111111111111213111211111--111211311112--1111111121112322111112221111111--1111111111111111111111M11111111112111111111-11111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111112211111111111111111111111111112211111111111111111-122213112111111211111111111111111-1121111121211111111121111111111212211112222222211111111111---------11111111111112121111111111111111111111111211111-111111111211121122111112211111211111111112111111221111112211122121121111112311111111111111132221232111111111111111121221121211211121112--11111------11111111222112111-2111112122211111111111211222111111211111111111121211-111111111111--11111111111111111111111121-11221111111111121121111112121211111111111111112-111112121111212111211111-1122111111111111111111---111111111111111111111111111111211 EDFHwur-*WP-RNeKLKLJJJHIJHIJJIMFKHKJILGJGJJHIJKGNPRSSXFKQMILKLEIIJHI3IFIIIIKJCJKHEJJKILLMNdPLROMLJLLDDIllo2***********************************************************z********6VXN*POMML****N**SF***** ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.7.1 C2 domain (Calcium/lipid-binding domain, CaLB)
[  54] GG9HAIIIKGGHJHHJAFJIIIIQ*TVqZbpxFFHKLHKJIJKJJEQNDJQUXOJLKPKNIIJHG6GK RJcFQHEIJJKIGHOLLSS-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-POQRQPPPQQPQPONPOOLOPNHFJIMPNOLQPPPPNONPMKQJLILMLMLC5GDDDEGFBFEEG667HDEDDFHEEHHHTNOBB9ECF9CAC9B99BPJLKMDKIGGXFYXWaNQSPPYSYVNONPCA999CA9ABMKLQHHHHHLMKLOIIIGGHGFFGEDCD9AL8CDCDDD4444434363743424-4443465333346433445BA8ACDDCCEBICD GC76SUI-eHC8HJaGFLJHJIILKLIKLMKIJHLJGGGFDHHHIILFILLLNLFMMLLGGHGIGDDF7IEEGGGFGDGFEJIHFJIHIITIFMGNKKGGEFIZQe3NZEbHJGEHFEEFABGASLDeGz*Q1WMaAEBAPDGLIDHGDAMD7OAFDEKXfmQqRDDLHMaHRgIHOUR*MLGWSqtu*H*eLLXNONJ -------------1-----2----------1----------1-------------------------------------------------------------------------------1-----------------------1----1-------------------11--- * c.26.2 Adenine nucleotide alpha hydrolases-like
[  55] 662244BDDCEEDFDB6598865GIBDE649I111353232231221122563-76555557993133 FPcJrGFNCCHFEDk*zdd-dvIIz*fdfffq****m***AxP*AABI7777FGHEDJ55RSjBVVhhXdO455545526B7Q96888LNKJ6ICB71-BKHHJWILIJ77999977788888CDDDEFCADEHCPSSaa445HISGHLHHGFEEEACACABFEEGIIMDBABBABBBBBACHHKFF666HFLJKJKLEHIEKKMFHGHNOOKKHKGGTNPI979889B9TC988998868A9988A7668B81554654342876746465554668665645455544445545544476774455456466544444558DAAB966777899AA9CC8898BDC87I99D8EEBFEGAKE786K68A6W8CaTTk46757FDzjmIGHmengaHJIKIGHEHJM1GFSFHbGPQYm4PJJINHPQOTUQOSOXQKOUJONMJPb77777777KBBA7UWM554444554435768868977877843787VXuR6H*pWqSXYXhSNMNNMSSZeVUVTHWdV*p**uABXZMTSPQQlYghp*GFP9655LG6676666688bUTG*RU968669B7965MKLDRBH8BQOMPWbED556665555555655555557677876JH7JODPERNGNMONOJMTNMLLPMQPKQR418BDA8223222DCIF8FBEGFEEECHGF-GHFHCCDFEHFGFCDFCDIGDEACDBBDECBCECECBCBEABCGAFABBBE74BBBBBBBBBBBD447LDECDCHIIJ7LVBCA89A79778759BB8TURRTGNLLIN9aaYdLXTRRQQOOLJJM6767667677ABANCCCCCINDHGLNKNLQOJKLCBBB55H8KKHHJJ33343443G531-----523--------5-------5B658655666F7D 7637RON2oLG7tmRPVSJWMSOYJZSNMPNOMLLMNOKNQJMQQRQNNTQPdXNOJJHHJIG68796485878898388A997A9444IUGVNLJCECDFKOaRS-O*U*fgdjmjVSUTUUSylS*S**u-*m*NTTXgVZhXOWSTNeMOvScbYtVmzNqbSIYLLhcakXQTQL*PPSWZzit*SqjhjiUOSw -------------------1-----1---------------------------------------------------1-----1----1-----1---1---11-----11-2--1---1-------111--1--------1---11---1-----------112---1-1-1-- * c.14.1 ClpP/crotonase
[  56] 76-4--CKPLNOQMMF2185774QH66842BC54A1--66664BB9DD88978----1113877---3 6BD9*B9877AJBG***jj-i*GG**jiijil********5*h*734B6I94JDQDEN11sdP8*f*ql*J4343444-6FEN32432CB9A-C331--5J554p576611111111111111256568536785IHHHI555*9INK8MNT2233443433633AWJwA433333353333A77CC--3FAjGGIGJOENIHMJNSF89LLOWGHVCLFKE77444444y63888888888888886765631213212121172222121333444223325218612211111111222222222312212212222224---B3333C33142a3BB11213-A22B62C3IFA4C5-1F81115-21C5ATFFQ11111BAwc*A68khjcY46674465658-JHQJIVFGFNQ-FFFKABCC9FRBIXAI9GIQAEEEFIQ44444444D9336KEG----------111111111111111----4GLjH1CTRGPRacbcftRZZNOMUc****RqkSsku*h56NNWGLLKHkKRVjg54N3144K7332222286ESHL7wXQGEHGBJDBBB2DFD8E99ACDFFD*hCG33321333332141-11-111442743EI48EAE8B99AABBBPEEAAABF9DDBFG--16DC4------K7ZFA87AAAMAKKCBA-8BBBAABABC9BDA99AAA98CQD**897899B999A889899F67788871-9AABCB977ACA--1746685BAAB6Ef7O333263133323334EEFLE6G9BAVFcgYd*plnKVSYVBgV*7444454543678KCDDDDBD8BC98A67666665444--63DD666632222222411--------------------------2--------2I25 I667dhG-dHAAKKo***x********hiimop***toromuohhf*n******yj**hXVVL9C9897DA8A8CCB8AAABBBHCFEEp*X*ZVRA8B8EDbdcd3P*X*l*j*esSQOPTYR*vNwS**n9ug*VVSVdRTiUKTTPMsOLmRZZTkVg*R*dqooUl*YduO9EKH*CFFLIeji**qwHHmbcWn ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.23.1 Acetyl-CoA synthetase-like
[  57] 433957A67887878765798885FDDFFDDD864566666584334536697345665564556399 4552211211112111111-11111111111112114232124321111111211121113341111111132222125325611232996A37462--12222625113333333223222223334643353334544435936232432222211112126154753221121122121212443335455858957556775755N4445757565444645555565766666545766656597657454666544445334556422356854944444544445554544544434445554544554447454647764444475575698866554664376843A7986456574577423322544533434465285443423333233323237-56446667A5725446554545345G5535374745444555555553865364322324333222722333223222224287248763223274445448333354444333233A4242522746155B45766444422333665654657253B4626L245574596744846566548542452541333533435532333333334345779DB795A6678799BC78867687688676511512342144467AE8777897777787-9A77987777977777779766E9HJ99778797998888988A957886571798989989988114634334243246756A6566677666688554584556645556875867765686567333333333199987889889A9A4221523111621311D43322331111111143264F32-2221232222224222222333-2223231413 8569B8G3J688FJFDIHEBIEDJHGFDDCDHCGDECIDHCGFEEEEEJPHBMPDFIBHJKIGDHGFFAEIJJEHNMAHLJIIJGJDCCFjMILLMDBG97GDTTW9EN8**********************Q**************************************Vi*TAAC9*9A99AKbebGdEAAEIDC9 ------11------1-1---1--------------1---------1--1-1-----------1-11--1--------------------11-----1-----------------------------1-----------1----------1-1------1-1---1-----221-- * g.41.3 Zinc beta-ribbon
[  58] CBA7E7EKKJJKLJJL9E67564JKBB9C9E9AGB89A9BA8A9778A6BBEBBCAD7789C676174 Ddx8X55989A464IjaII-KW66iqIGIJIWcVZVIbhf9fM*XLHCBDA8YLREAE44KHRBWHrabdC5333B98B8HAV55574FGAE4G882--7M7DSUBSGV43333333444444636574523475FFFHG444CNGIIEBCBCD99876865B7CGFHOG886565789555CCH87674C7FGHGHHIHGDGFHIGGLLFF7DGGKDGDHHA9BCCFB9bV677777757777777D78A9G8B677784867955CA867467565668A6667765546567664544444455465467888856774APCHQMMLHJNLHOKCPFEDCDBEIFC6EC7E8MKBDHFDUIDCBGB9C9c8HPJJN3333477jcd658DA9E9GIHIGFJHIGQ-FDSECPFTRWI3ZRRWNJNhTQZaTJHNKKSUIGIILMQDDDDDDDDFEED97FA223324442211324722323222132227FQ*Q7CTOGJUaeeaUNJJJHWWfaPOOOGNhLnWfdT49IFHHHE88PNVGea8DB897CB9556444467CAE99NTDAAEB7D998A3CFCADABACGFCFVbAF586569C8A9988555775565A7D99JCAEE9ULMLCGEFFDGGLGCC9HDHIAGK2-5A65C312444JEGKKEFHKKKIJJLJJ-IJFIKJIJKJILKIIFIIFOQRADDFFIDGFJIIJIIHHIHFGNCA7BBAC75HEGEHGGGFIHG444P55456ABBA7CODO999879877654567DECCFAC5B8KHQQQQOaWOJLMOREKKNC886897888DINU99999IEGJHIIHJIKKHHH6868227M9988B949855463A3432115-67A87537866BE3A6EEEBCJGFAEB9CAG99 **JS**E8*MJ7EFKaRnWoTbYwspkRQMOPPNRQLLMMMMNTQPdWinoz**WaUaZZUYBKV8GK7HHGMFIGO9GJEONQDJA9EY*ZRTeeKIJSIRLSUM2M*v*t*jmogZSRRVZX*tV*S**m4zh*MZUWlUZjVRdXTTZTLwRmYZhIUYdvdRirPb*TYdL7JOF*GCEJKpTdnhbPLRhTodS --------------1----------------------------------1-------------------------------------------------------------------------------1------------------------------------1---5---- * c.1.9 Metallo-dependent hydrolases
[  59] 662953ABCCCCBCBC7366755AKGGFBCCF231121211127744253767-BEBADBC96792DH 3JH3u459A9B674MJHCE-CG22QaCBCDDHNPRPYc**7UIRKRBB7A93OISG9F11UXL4YJWfgVF3222-11-27581242378A819122--5C4A9M5H4E--------------1231111221315777622278C6878852255257846172C76A4655655555675FBC43---64DHHHGGIHFCGFGGGHDCBBBJGFG434E6GB99AA98KP377777757777777767883421221412155443322122-4231121---22223331311211111-11111111121122211111436D3332233223325532324121-1324387353312241111-36B-AUHHQ12232BBqXa778LGIPJHJJIHIJHJJY-8AK79T7JS*F-pZZMbdtqenacNIHN7PRcMJLLMYb55555555DFFB4BDE------------------1-1-11-----14MiDCHVUNXlkpiprOMLLJffhgQOPOFOldiOWST13JKMKMKJKOHaDbA9BD6424G586678575158DA26B575C349C44427252214269686DN653541122112--2-------4111344CDA5CCK6OC6ABBFDECB9ABAEACDACM1-12223------9CEG9F9BBBABAA7AB-BBBBBAABBCBADBBBBBCJHHCF679B9BCBBCBCBADACCCMA99BBBA6-GDDDEFEDDEEE---921211574626OCO76687E444553546IIHFJ9D244FBSSRTOWTTMOTSLCJGI3234444424AACHABBA9GIOFFDC8C9CC887------51442222----------21111--1---1--------1-----3------1-12E26 12--CC5-B421566GBF6IBGBMKICAB58697795A795978BALHHIJJRMFFE9A987455344113134422132323222111AHEBDDB89996C86D3-4O7**********************G************s***l**j******X*x****x*******Y3DJFTB8988G99WEC5B7GDFDA ---1-1-------------1---11----------111-1--------------11-------------------------------------------------------------------------------------------------------------------1--- * d.58.4 Dimeric alpha+beta barrel
[  60] 11-51167A888A87528332445H54A43GB67I655879B7787EF8BYKJ9555458A5238118 BUj6g467EFA565TIGDD-DW33KfDCDDDFVQSSSiukCUDYCLED3654PHK64C33MHP8OGYaiU675554633766O64454TTPM1N452--7OAGCrBd8N111111111111113998CCEBABCECCCJF111J8VIIOKKJ5AHHEBEJKHFJ7FNOZHAD58A88BA74CD7844874A8IJJJJJHIMANLNJLNLIGFEKKOM5D9HB7CBAACA8R*6888887887888779778BD7738B48846BB31AB3M366657679C655656555545555545555555555755573355433385CDAaJJLJJJLDKBDIIG6AF9RB9677DF55PQ9B2454374529397E5JUGGN22333NV*iiLCKSRJPOFEHGEHHEGGS1WUnSXqThX*H3*iibrxyvvrmoaRHICSbZVDQPaUZ99999999JKMGCLHJ1111222222222222222222222323369HkC5PjcRV******iVbaUrr**iegfLe*y*dlva5BVYaRMOABZHpP*NLVJ7IFJXE5778998969IPJFMFDDAHBCHF9AF5LHEGCDMJKHJJGWjFEB494433355324443433362577EETGJLKHXAMDGGPQPOKKHNLILLKMLJOK1-3995E------ORNPBTGLVURLRRRMK-YMLMMNOONLXOPOOKPOFggeQWLOMUPSRRQTRTTRRVRRUdIHGHHIGA-OJKIMLKKMLKL112834334DHFFEBYMi5547492211-4565KJOLKHJ799QFwxzvisipSjghdHcdd945256634CMJIYHGHGGOSNLPLQORMQOIKM787842F8EE99GF22222232613------111111-222112-1----47456897975R8D 4313LCE-H7539FHVdYOXTbQiceZDDEHHGFGDDGDGFHGHFERQYbm***VVPONIIHF8B7686A8799D675779DDEBE456RdGdDKMJJHDA7BCBD2H*I*PhORONEDFDFHEbRCSDx*R-PPdBHEBQDKQJ7GCF9IC9PFHEJLJFGPWLIB79FKEHOKDLLJ*FEGRK****T**QQSIEJX -----------------1-----1----------------------------------------------------1-------------------------1------------------------------------------------------------1------1-1-- * b.82.1 RmlC-like cupins
[  61] FF8DCEGFLMOLMLMIDCDJHFIQMQMMJFJLD8BEGDECEBFOJJITFEZRTEKGJHHFKBAAE668 GSa8WA6A9A9767FKJII-IL77KSIJJJJFRMNNJRaU6EEIG8993772GGHA9D22IJH8GJSPVNE2111321969GQB8GGARQOI5OBA51-ES8LNoIRFL54555545655555J848987476G7QKKOO777cHPNPLNLKGECDCBBCCCEIDFSSVSABB9ACAC9AAALHFDDB95EHRcZfZgcadJbZaXbZHOONIOfeZFKIPLHGHEEFDFbS8CCCABBBBCBBCBCB89BBD886A9667777888AA87746476687887776788888888888877778777887777776667779FNDQYTTTSUTTTUQAPONJIHFKRI77AB9FANMFHHMGLGBABAF9FIMJHGGFM55656DGgZfFDAJLKKJ6666665666B-NSMLSQNHJML4HKLIMMNNKKPLJQCHAMELGGGGLGN66666666DAAADEC9222223323287647938C44377311139DJQF47C9AGJFFKGMHBABBFELKGFGFDFJJMLTUO7AJPMLMDGFJFKDKGCEGDGGAG64456865A9DKNKJqUWIGICALREDH9JQMLMKOKMMLXNtpNL67346667643335456465B5BAC88BAKGPFIDLFAFABBBBFKGBA7ICHH8OM2-2CCDF11-111ABEL7DA9AAA9B9B98-AA8B99A898AC9999999EHHGC8CABBBACCBACB9CACABG897877A62EFFFFFDCFDFC334C575569CBCADXBC666C88533336676DFFEE8A69ADCJLLKGGHEMHGHHHDCG846546544HDDEIDDDDDBBDLLEHGCGCCAAB977735FPNPHKHG68649766G4622225-22322222223322322228AACDDECFDBSBF ND4AQOV-xQNHOSYQLaRZWePhVeYKKHJGLMOLMJFFBHGGJFLKPfSUwePPMTLLKMGIECED8GDBCAGJIDIFDCCB9EHLIKcNLRMdLFLIEIPVQa6J*i*fukmrpVZRSWdU*tW*Y**nBtn*TYaTlWbydUZWVQpUO*dkfYmZjMQxaVPZTSfUWt*EibO*PRRQUhac*Qs*SRXRPaT -------1-------------------------------------------1-------------------------------------------------------------------------------------------------1------------------------- * d.157.1 Metallo-hydrolase/oxidoreductase
[  62] 77ABB7HGHIIIHHLE7CDDCAB6A78B8BAB9A8686877667757556C799BD8A8898867287 BAL8J335556453BCCAA-AG77CMAAAAABGGHHDCLJ5FBA97555444B9953G22IIC7EFEKKG685556662364B4576475AA4A325--5C7FEPADC6111111112211111644477454C7A77FE333FCDCKEAAB76786665477E9EFCP8348344333446B778753468BBCCCCBBA9CCACBA78AA9AAAD8898F67577876D84778787777777776977867749746746AA449776544385632323233332222322222222222222232224224442224662486668695766475524437272387655B9A7655B676657452H5CECC85535488IGI57BACBE97778757677C-HGHHEGEL9LA3IBBEBBBDEAFEGC8BACCCBBAAEDD9999999989A8CGGL3332322222--111122211111133348A9DB5CIGCGKKLKMLFHHHGIIKJJKJKCHMKEGIII4CIEEFBG8BIBDEFHCEDA667EA35444447B8DD96AA9959D6BA99748656767A7FFBEGOC79736444556433333333378567A9978E89I9B99DABAADABEBAAFCACBAG3-4GE8D221222B9FD8BA9BB99AAA9A-998BBB9A9A9A999999ADDCCE8ACAAA9AAB999AABA8AFC9BB99F84B8A89AA7B999--48565557788E7I7B555757355646565999997E887CBMKHPHEFKGGIHHBGFICBAAAECCBABBC8DEDEEEFFDBEGJEJEDBDC666644E67777882111111281-1-1-1--------1-----1-1-1-47554585446927 JJGGQUsC*OHLQRUTWVWVWTRVUWdRRZWRSWWUPUSTRSUTVTYVUVZaZURVWWSTRSSTQLORDPMLOPPRSJRRNPOQPLQRTQhSWaUbXRQSPeSXSgISzW************u*********9******y************t*********************kRTTP*TVVWW*g**VysenpjTSc -------------------1--2------1--------1------------1-----1-----1-----1--------------------------------------------------------------1-----------------------------------1-22--- * d.153.1 N-terminal nucleophile aminohydrolases (Ntn hydrolases)
[  63] 664943C8BCCCCDDA7GAA898AD76CBCC8A8CCDBBCBCBBBCADHEGDC778467789897-7A JKc9OCCFCCD7B7GGFCC-CK99GVBCCBCDOJKKJKZgDFFHCSH8DCB9RLN9AD44EEQFJGZPUSD6788A79BADBHDBEDCFGIOAI772349F9HEGBMIL78888887778888ADECEIDDEJFEFEELICDAHFKHHHJLAABAAECDCBADCBGLONGBBA8BCAABA8AGC9EGCB6DAGFFFFFFHIEHGFFGHUMLLGHGIEDHJEL8AGHGJGHKJ9EEEEEEDEEEEEEEDBBDEF561GN25257CD44KN674455898BBCHCCFBBDBBBCCBDBACCEEEEEEEFEEDEEFIF877FEEFHHCIVFFFFGHFNGLIQFFEDDCJ9G85CAIGEJKGDFGD8FKHFCG58DBEQEDDD76769GBaOSCDBHIFGHHHFIHGGGEGO-CAJBBTBHJPD4dSRLVXXgeaYXPHCADGLQMIKLHII88888888HBCB8FHK5545544454223334333333333545598EGAAENKIKSXXWXSUFGHHLLSTLLMLHOdMVJNVO99ONLOCIHFMMSJUTDDDBD9DJBAAB9AB9AAACEIAMKCDFEGDHJHEF7KGJIHFFIKFGHFFKGJDB9B9DCBBE9BB88988889BAAACDLIPHHDIBHIGIKJKIJGJJHJIIHKJJJM447DCA8455445QLMFJNEWWWbWbaZUU-WVSVcXVUaUWcYSVVTUUXXXQMMKNUKRSTQUTTRTOQPRUUNOLPONND6JLMMONMKMNNP667BAAAAAEFGFEBNJSDEFGBEA99A6CFHHHHFGGEDDC9QDKKKMHJLQIKKNIJJIJB79678777AIJMSEHGGHJLGORCEEEEDFDFG999998FGEDEFHH1111111195412123-21533324442432432325HA77AD9BAFLB9 746499N-H5B8FIMUTeXgeZWoihZMLPKKKQQLMNNONMNIJLRURaklojWWXTOPQNHELFED8GFDNLIIGBIEECEHJEDBFNjSTUTXKNOLHQHWOa2F*DfRSMQMSMEPKDLFhZKYH**T-fPsDIGGVGJNIFMIEELDDbIOHKRNYHLROPTdFEUCNTHFIMG*GGGJQkYwzXsULSaVRQQ 11-------------------1-11-------------------------1---------------------------------------------------------------------------------------------------------------------------- * c.1.10 Aldolase
[  64] 994744GMOOQOOOKH46F9BB6UH88B949J45444455554454454454544544554ACC6-77 9FOCx9-C446686o*rXX-XwAArrZYZZZazz**r***A*f*CAFGACA8RRPEFP44fia5Uao*xoN--------444O64644C86E4A4462-GZRQIeRVFK4444444444444456544A454645HHHNN222PAE4CE7785444776666687D76N9464444464444KGJEC222ICPKKKKKFGMGKGNFFGEOBBDIIKGGJFGMB6888888TG4DDDCCDCCDCCDCCCCBBCA4987788484888888888A88AA8997CAAA66A66666666666CCCCCCCCCCCCC888666888A58BGDDDDDEDD8F7LCDDE77639B21K79B7LKBF7G6CJ745C5788L4IlXXW999AANGdWaIIMZZeWRHJJIJJJJJHM-HHPHHYDNLUeAQPPIQPQRPUPNLYNOHINRKJLLINP55555555E8879EEK444444444422666647646644644444OOwP4GocMibQQhbdSTTTSNNhXaZaaPVrd*Tuti8ATVTNKQWUZSPjmdBCP486ANC7666664888XPQF*PWI47654D6664QOMJUEQFGLKGLenFH464446664686477677775444577LK8DKHOGHNIPKMMMNQWMLLMRLRLMNT4-8CE86222222IEOF8EGGMKKGEEFGG-KGGEEGEGEEKEGEEGEENMONLEHSFDDCCCDCDDCCCDCCDSCCCCCCE92HEJEIJJFJIII446FCGCCAKLMM8LOGO6664B5466466684MLSTMGQHICQBddaeSiTcSaMYQKTSQ8666666668ADDPDFEEEKMHOLJJOLMLLUYZ8999668EAADFGG444444445-A-------------------------76644282225J6E 741-FLE-RBA7GKGNRZRTNOQeXdSJKMOKMJMONPNQGQPNMLOOMNPSUVKLOJINLLEBFA9D2EAAEADD88CAAEEFEEA79KRDRKGKDGDCIHDTJN4NyGZSXJCMPMKIGMMJheFoE**Q2eNhNKHHTGLQMKJCNIPGIVHTUMVILRHQQHLUIKXEJXHDWaG*DAEOW****T*qJNSNOE* -------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------- * c.95.1 Thiolase-like
[  65] 64AB68GDEEEEEEFG6FEFEDDGD99DA9FEDBADDGFGFFGCDBEDCFMGIAAD9AC4997873DF BCKDUB8CAABA88HHGDD-DI88GIDDDDDBKGHGGGTTBMILFFDDCDD8IHKBCE77NHLAQJVMNHHA999C8967BAFCCCDBGEIF5I663337CEFDFAGBA333333333344447BACBDC889FCFHHIH766MHLHLMFGICEBB9988B9GDCDONPK88888A898888GACBA689DEKDCECEEFFDEFJCEFDJIIEGFFGGGFHKEF9AAAA8SOCCCBBBBABBCCCBBCDECDC859BBCC7A6FFAABBA9A8858888887566C88788797877798877787897778A776668777AP9CG888AAB9D8CDCGG7999A9A64A68EAMLGCFA7I999989358DCHMGGJA99ABEHUNQCEFIGIHKDDDDDDDDDDF-JJMIKRJHHPI8LGIJHKKJIKGHFKEDFFDKFGFFHGICBCCCCCCFCDDDFII998898888833444444444444499999FHIC7FPJKMEFFGFGFDEEEDDEUGGGIDDGGNMUVQ8DGGCKJHFGNJHJQPCDHEEEGID9AAABBAKGFNGG9NZNEFSDBHPFGI8EEDDIAHIFMMMLPZNQB98B8AAAAC87B7777777BDBDDEEHFEGJFFDIFJHIFFIHJHHGGIHHGIJIG937EMMH442333KJIIHIELLNMLMNNLL-MLLLMNKLMLMMMILLLLNHLIGGJSGJIIJKKKJKKKKKKJIJKKLLLJLE9EFFFFFFGGFFF56AE99999IKJIHIUKIABAECE78888999AGGGHGEGCBCHHQPOQKRNOLMILIHSTPDEFDEFFBEGDFEIFFFFFHGHIHGGHHGHHGGG9AAA8AG6HHEEGF11111111732------------21-1---2--11154545696879D9B 9824DEP-nIKEKLTPJKHOTPOYQWTKLJNMJMOMMKILLKLJKJIKDKNQScHJKKIGGILEEDEECDDCFDDGH4GGEDDCEEBDEHPGJKGMEEFHINDNPL-KvR*cbekflQVWQXYY**M*S**l7we*PTVTlQWlSNTTMPmUOlRaUV*YnzSuWIKqKR*dYhLKSWN*KKILNiOipLcVNVeeUUV -----------------------------------2---------------------------1-------------------------------1------------------------------------------------------------------------------- * d.142.1 Glutathione synthetase ATP-binding domain-like
[  66] -------------------------------------------------------------------- ---------------------------------------------1---------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------11------------------------------------------------------ 1222--Q-1-----------------------------------------------1--------------------------------------------------*1-**********************Z*****************************n***R*imqNm*7---1G1-----------1--11-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.18.1 Complement control module/SCR domain
[  67] ------------------------------------------1------------------------- 1----------------11-1---1-11111----------------1----11---------1-----------------1------1121--11---21----------------------1------------1112--------1---21-----------1--------------------------------2223-3-2-221--11--1--11--13222222--------------------------------11--11----1-----------------1---1--------------------------1-1-1----------22---333---1-2------1-1----1342---12-----------------------111111111111-------------------1---21------------12---------------12----------11--11------------------------------------------------------------------1--------------------------1-----1-----1-------1--------------------1--------------1-------1--------111-------------------------1---------------------------------------------------------------------111-1111----------1--------1------------1--------------------------1-----1-----------------------2222222111------1-11---------------1----------------------------------1--2 ---1UM*-F83-fe*FINGNKLMLJJLKKKKJLIKHLNKMOHMJJLPNMNNLOKLMQKJLKLLIOJMI8NOLRGNKMBMMNNOPNQIMNLgSIWSeLKLLMcQsnu1*FC**********************l*********************************u*******r--2-11--224599I53-14434F ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.34.2 SH3-domain
[  68] 77A59AIDLKKLKLJEABFGGCBDC9976A9CB7C86DFEGFFFDCEFCDHFE9DDADDEF7CB8-33 GHUESAACDDBDDALRWJJ-JJEESXJFJJJKONNNNSnkGLMVDKJGEHCAXOXEEJ99WQVESRoTWLF6676657CEGCK8A797KINH9BDD446BFBICKEHDF77777778889999BCE7GCB8GEHFMMMGH77A7GEHFGDCHBACC787796ADAFIKIBB8A7997B7777BC9BBAA8FCEIIIIIEJHDLJHGIIFHEEEFHJEFKKCCEAGIIHGFDHCDDCCCCDCCDDDCCBEEDDC863BB49528KL66985B89B9IDB79774664668666668686844444444544446546666668JNJHUABAACBCDCFHIBB7666EEH77KAAGBBBBCFEDIEKIDIGIDAEHBNDDN88988LIkaeHDJRUYVWGHGGEEGEEGN-GHQEGVHUXSB6PCCCEEWMGEROHRGGEFJLHEINIHRKKKKKKKKMOL99MLI66666666772254544445545546666BAImDAGMJFJWSWSTUNJJJLOOSXMMMPFPNMeLVXK8EGFGJLAGDJJPTePACLGA66DC66666668ACIMMAMQDLEHDCFGFFC7OQPHPQRRLNNPNCIHO788997879876766666679ACB9HFJENBE7CCC9FGIEEEGGIDDDDJDEGDOK826HDDA666777JHJGGMHDDDHDHHHDD-DDDDDHFDDDDHEDDDDDHPVRPKFGCKHGIGIIIIIIIKIIJIBCBDDDD87IECEDEECFEDE679DABAAAGEEEC8IECAAABBAABBBB999DCCCBC6AB9AN9NKLKFKDMDDDJD9HBD6887878886BCCIGHGGHFEDFEFFAAAAABBB777755D77877B9-11-----B5422224-6447674665457445222DDABCAG9DADI9C CC-3HCG-eDG7DEIRNRNMSWLZXWZIIIHIGFKGJINHKGHHLIRPOPSVZiQOKMKNLIDEFBBD9EEGEEGHE7DECBBDEGBEFKTJNRMMKHMKHBEJLP7GfHaaYRUMMHFHHMOJdeOiJ**LAeUpONJQbOMXGDQQGJSHFbDQJLLJgoEOLOMuOIuHHZDOHIF*FJHNHaRqnKadTPWOLKF -------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------- * c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
[  69] 664A24AADDDDDDCD3BAAAA8BKDCFECHGBBCDCDCBBBAHGBFIEDLLLC7B5AA88BAB51AB FJaDYBCEDDEAF8LHGFG-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-IGGHHEHGIHIHHEGGGGEPWPGHIGDLJJIJKJKKKKLKLJMLDECFGGGE4ECBCCCCAACCC776D68568CDCD9EQML888A7969A78957AEEFGGDEADDEBXWVVOYcbSWWUWKOLODCDCCDDCC8DCDLEFDDFFFDHIHGFJFJICGD998888CAEEEEHH4444424263522224-222323122223424111265855D5CBC9MCB 9845HEH-F654EFJGJTUKQUTSUONKIHMJLJMMJKJIGIIKHIKLHRSXfbMLMPNLLMEAFCBE6FCBDCCLJBHGADDDEGHHKIWHJQQUHGGHFAGIIJ3FlKVLPIBMKDBCBBEATNANBf*H1KHTCB9BI9CEA7BC88FA8LCHJDNFNICRCS9E9GYBAcFFIEC*CBBHKeZntOqaDQaMKJG --------------1------------1-------------------------------------------------------------------------------1--------------------------1-----------------------------------2---- * c.23.16 Class I glutamine amidotransferase-like
[  70] 55132311211-323-4-555665D2258-58---2411-122111-92-1-1-1212131---4-41 AFH7*339BDG23223311-18112V1111119888AIWVFfE*erZ1ORK8gZf22E22HEUCkBdqreCNHHHOTQ6---H112--98CB25221--2E183F4G6I-------1111111111233311731HIHED332SB97997773423344342444288C912-11113-1-1KL987KI-KEEGGHFGEDGBGHFCDGMRJJHGFGCAOS8DCBABCCABKt54444444444444452278HBC5DD5F74AJJCCBF977FIA888CBCDDBDA99AAAABAAABBA9AAAA999A99A99CC887CCCFFE8BuAAA9A99DAFDD448CBEZB873D2H85BB7B96S64AGCIL46953DFDD412212H6***63AdIcgRPRPWORRMRQl-BEkCArFZJ*2-*ttm********WbC26RTZNMNQSJQ33333333YHI36E4H----1-------22221221122221---44A882IYTJUejmlpfQMNNLcc**TRTSKVfc*QdcN15XYXe8PKNbcnSx*9DC-513FA11-------1CHM5JG376K96MN89A4968B8D77555557a2N3-113234442-----1---222--11IIS99EE1D5MABBBD58A9893678648C---3213------bYZVCZORTTTRSTTSQ-SQOTUQRRUTSSSTUPUUQoppUVCEEOOLLMNNNNNMLNLKLlMJLKJLOC-XcdddefYceef---111111323333SFYABAE8H27898BCGD------4232SCBBBCBIJVCIELEBSOP2--------4GDEXHHHHHJKFNNA8CECEEAAB3433--AB--11--76656355457----1-1--11--2221---22---CHLC78TAE9-b22 4-223361E9*134A11222453121322-23-2---3122222132-3111332314-5643-11-3-11141221-----11112-115-1143---14-1657-AoB*******VPQQX*W**L*V**s1*j*QbRO*PbgSHbSTNsIH*TfVe*9EIa*qaOlOP*dsy*254-3---11KDD*2T84167427 ---------------------------------------------------------------------1----------------------------------------------------------------------------------------------2---------- * c.93.1 Periplasmic binding protein-like I
[  71] 11-11111-----111-1-----333324321-233331111-44-133253321113222112---1 3541211111111122211-13--3111111223333345-2111-12-111112-----22-121345211111-11--111212212224-223---1147511-3----------------31121322-421111-1111-9A78444235544456445326765162211161211113------41334343353444444132112424222123211111111--------------------211--1-11121111--1-11-11---------111---11111111--------------2211-222--3-1211111111-2-1112----1-1111-1-11-21--1--------12142112-----22321--133422----------1-333331-5231-1---132324222242222--1--134111111111111132-------------------------------3221-1111-233463-111111353333134221313-211113----21-1---4-11122---------3112-4523232175112-111221133----1-1521111-----2-111111112-2562232-443422533222222622234255355--1-222-------1--31-1111111111-1111111111111111112111----1212111211121211211111111--111111111111---2---------13523---------------11111-12245-222212132212233122111-1--113234111114544511222221111111--5-11--11--------1------------11----1---1111111211111112-21 2423C4L-J97164A44544896956643112122233332223316843449833341444641122-5324-333222322334-217B3497B5338664CA8-4xK**********************D*****************************************n5lkZ*MNQE7ITJ*4tMTZv*w** ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * f.14.1 Voltage-gated potassium channels
[  72] ----1-2311111122-1---1-----2-1------2-1121-1-11---221-112-21--21-1-3 166-G222111--1A9866-69229G6666676AAAAFJC1NBO5547121-3331-2--665-73CL9H2----121111-21-1--2211-2------B366J7F1F1------1-1----31--1-1---31-11-11--2-M28B8845544887442352AEALF1753323D22342---------12222232322233323111-1324---2---------4D-221221122222221-1--11-1--11--111----111-1---1333122222243344534343-1---1--2----4112221111-2-1----------121---332------2--13322--1--1422--311-6P9AF----277EFI4335443211121111115-25833A443JJ-92285548976634EAA5B5222297A888888885553-422-----------1-122--2------1-2-4EBPF-8CA9DJNPMOMPKLLDHHHJVUTT6MSGWHRPK14DDB6A955G485H67816955632253443233-5-9-1-2-2-1221111---1---123312OI-2331--11111112111111211--132A8486DE7D7A9EFGE6C8B77B9AABB9A--122-4------9B9A395CAABCCA9AB-AACBDCACDCACDBBCBBAFJE8BEI5BAA998AA9A99A999GB9999992-C898A8788999--46---1-BEFC25PDB443434233324114555754D346LBLKENHJJG9HMGJBBCF3231322222866A555557597766FCECD999544411314411221--------------1---1--1-221-1--11-----1--------114 9244ji*-nKW4NOj*r*i*w*w***yZaQYTVgYXgjcfehfZbf*ut*****ur*kjmjnWPUGNM8P97PLYDDBDFFSSQPODNGv*jrlq*iimfUbVbhS1e*********nosjq*p**l*u***E***hssk*kw*wazngb*fa*r*vu****l***V*ZbnSk**Atz******z************** -----7-------------1-1-A3----------------------------------------------------1-----------------------------------1--------1-------------------------------------1---------A22-- * b.82.2 Clavaminate synthase-like
[  73] 552514ADFEFEEGDA4B877A8LA77B576B977576675575457645465248363447665166 CJK6TB7C88BC99LLMFF-FJ88IXFGFFGFORLSIOZZCLJUIHIC9FB9LMOFFHA7JFL8JEZSZQD66668553364G88667BBEA7H771115DBDBJDJEF33333332323444456657665775DCCCC456CAD7A98978878666668866BB9E8565664474755ED967764JDIHHJIKHIJDJIJHKIKHKKHKIKJFIHCKDB9AA9A9PL8BBCCCBBCCDDBCCD889BC3848B39232A9779868589698A4455444555588666665665555565545555565445555B6E4CK4444554A6AAABB866596776E8774PMCD7G6A97B9A6323J9AKHHD24444JDXRQHEGHIHJJDFGHDFHFFFM-GGRGGcGSTQC2VOONNLQPNMQRNPCADHHSIIJKMJTAAAAAAAAOCBAACEB33243444121124331342132232131ACGPE6FXPGVcbZZbbSKNMJZZecUUUUJVgVqNZSO7EOLJLILIHOPSPYU9BF8978DE66666669B8NJG4LFGAA876886775HDHBFBCA9GIDIHJBD966666546645665665556668597FCCIGBGDJHHFEFFECHEEEDEGFEDDGG333CB69442444MJJGAIFOMMNOPOOQO-MOMOOONPLOMNLLMNMMOOQOLMIGDMIMLMKMMMMMLMKLLMIKFJJKMC5FHHHHHHGHHHI4467AAAA9A9998ILJKAAAD8A35655A889MMMIMFKDDDP8QSSRJSQKNRLOSIGEJ6696877669FCFIEEEEEIHEHHCCGDFDDEEG667743A78888BB2222222233421112-113211-11132412111135855776779B7D 763368G-XGC2IFLdQXSVUVSghccIIEHGHFFHGHCEGEEGEELMGPXZkfMKPJMPONAGD9995ADCF9BJC6KDABBA9B9A7DUGQDNCMJLGGNEJIM2JtMgegZraeONNNLVRkgPqO**Y4scwKLLLXNQZNHOLKHcMLfMSQQYJTcLRLIGTQYdUYMBJNRI*FEGJHfXs*RaJNNWLKNR ---------------------1--------------------111-------------------------------------------------------------------1-------------------------------------------------1--------1-1- * a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
[  74] 66FMCHNGOQQNOOOKMDMNOLNjC6684B4DtTvjfvxtqouTbTZiMbvqocKMESMPR9A9N288 DLXED3445546267LJDD-DJ44LLDDDDDESQVREENMBECD4674644274532422HFGCCBCFHC833334337N**C8GGAFDCOH6L6643368669C9898111111111111113JNLNFJKLMHKDDDDBYNR9BBCDDBB988AA8897679979IDD96A75555C556678677KHG66566776867676677673773776856952225555557844444444444444453343811-11-211122121111111-33322222221322222211122111111111121111111111111PkdMtabZddcdTbQOhhhMHHDeKVCCYEBYj**ryhTUtqzRPRTH65DT8877D55555GHPGOFBFNQNOL99A99BAAAAC1GDLDFJELCE64A999DFHBBBHEGH68BLEDFFFGHEKAAAAAAAAHBB47bBK33444444334444444444444444444869H86CHGDOLIIMKLEEDDEIIISHGGGBHLMQNPSK9ENNLVOEMLITMdSIGINMCFACJ6766666479dSW8***os*qg*sllm4yxvzvlsgeXYaYCNp*EMJIGCCDDBD8E8888898LUHNIDDWMD597D6897GIKJJ6HcNLLLLLSLMjR5-29OJF453555OGOGQI6VYXUVUTTWV-XVUXVTUVVVXUWTVVVVQILJKG78PYTWVZWYYYWXUYTVWGMPLQPQS61GDDDCDDCCCCC3349676676778H6CD9999CA96A98B755BBBB9B89AABL8IKGICEEB9DBBCG7BBA766697679CFFRCBCCBHIGFHBC8888877777779BPFDDCC9A11111111G2411111---11-1-111-111-1---FHDGHLIMGJBO87 11239CE1D46*756545565555657765555565543534547644656755565555456563221532554331333565662226644747576555556C-7NRO7JDEA54897785JE4D4R*D2DDM9466I47AA5764695495C87A6CJ9L977E6DB9KA29BB6*77489FGNU5AA69C588A --------------1-----------------------------------------------------------------1---------------------------------------------1------------------------------------------------ * d.58.1 4Fe-4S ferredoxins
[  75] B9ABBBC7DFFEFFFBBB997A8CH77ECCEE9AB886667668B6D7A7CDEDBCDEEFF633G435 6GM4G83899893686766-6945886666669666DCEE3GEDEBB9587369D55421CC86FCGKHD55111A88446CF73567NQPL-LA95--8G7GEOAMBK333333343333334A9BBD78AKB79AAFG346LCGHEDA9C9977748595886DKJGD364122262212MGGAAAC97BFFFLGMLNNEMMMOOMA9GGEILKN7A9CF9BCDDDCCNRAAAAAAAAAAAAAA9FCFDBC6B5BD65755DC77EC655857A9A6676333855555665456343333333333333A8887588864DBGJ6668877E7FCEAA9DDCIBB99E895766FC796A977987B6AH7XA77833332BALOPE68CAHED4444444444C-NKLHWKMGBJ62EEEIEGKIFFFG8989499C9A9A79A44444444999548B911-21---11-------11-------111256A53BEC9BFFFFGEDCCCBEEEMFFFE9FFLDDBEE46CGDDEADBEBA8K6797B533A3334323333377ABFHCB7A95B76663A99A898BAIIOJgjBB742462223123533333335757B759A97H9C999DBCCBA88BCBA98BCEAFC1-5896C11-111899B686ABBBABCE99-C9B9CCB9B9CCABBBABEAAACC78ABABABBBBABBDBBAAAA8787698297776A978766223544334566675M788888884666564469888878686D7999A89CBABAAAADEC3222232225AABCAAAAADB9A978777779892222457CBB779A43334333A3411211-22122123333122311119C9AA8A8986EB7 IHIJhge1*fdSNTPSaYVWZcYcbacZXQURVaTZbaZYWXbUSPSZXfdafeRWTbUWZYVJNMHJCNIKLJNNLFNMJMPPNRNJLMiOacRdOKKLIOLfYe7k***o*dpgeTRVQQaRvkRzS**l-uY*PURQiLYaRNWQQTVOP*QXbbjadoZmfRTuagev*uPIYYV*ONPof*w**Z*wam****p -1-1-1-2-----------3-1-11----1-----121-1--------------------1----------------------------11-----2-----1-----------------------1-----------2------1--------------3---------2---- * d.159.1 Metallo-dependent phosphatases
[  76] --1-1----------1-------FkBDP8UJR--D-------3x*1L*4IuNU-11----1---1--2 KOX39--1111---18723-294438222222C66644A49J9FY5--122-7792-211-2D-I47LIC5-111--12-329AE995HHCA-B22---3I764MOIUI-1-1--11111111354377366Df9bYWUWNCEg4XJd*NN479GF242443CO7Iuo*9111111121111W86438B8CFCGHIGIJHKAJGILKHGEDDGEJII9NLDBCF777786QL455555555555555533323231441233332224432321223222322221332221222122233333333333332--111---13WI9YJIIHHEI9GA7KDDB68857632D42EFecMWEJ5LH665C3211ECPTMLJ56546BNmjfKEKmWbkZCCCD9CBCCCE-yprpkY*xAPA4JUQLPNLUSQJJNG789EDAQTNMBNA33333333AFE53*Vo22122111-----------------1211-BEEA28975COFHOOMNFEECTTRYMKKNBMLSTMRNT25QSKqSWLNNNZpJ9JGeGJSXaP-------97HWk*F*vSMY*rC*y**n1wd*pbbvYrLPaNg*GeK474-3443131-1111111NKDBB64ZQITUShKONbUUTXYRVPaWXLUTOQKWb--2JaWP------A5HA757A89AACAB99-5AA9CAA97B6AA79AA97685CDHK66454566666667646B76344478-G57656644553--5D68675BEEEK6fBU----1-----11-125666646252KUVWaWVaNVWZVZWbVXa211114111MBJILNLMNLJPJRQGFKMJLOCEI1-1-1-*1iiMLPO11--1---314--------1-1---------1----8E698333333r17 -11-ED7-642-52FEHFDA86987787758692-32333343779FGBAADHCABD98EEE332444--4631236-46222123245697H7869884CB5EFI-My*RnlmvvvTVQUUfS**P*T***7*j*PYROgObckMbUONhMJ*WlYfg9GFINGKAaMKoCFGC-Yf4r445IDcIFTEXBHSMLMJJ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.110.3 PYP-like sensor domain (PAS domain)
[  77] ----1--1111-1111-31-2-1-511343212----------2-215--331-232-2-22------ 64E3H8BAEEE95874877-7822AD7777777777ILCB2G9PFIFBB9769AC37H229FABP5CNOX78888898G6XF3222117853-435B--4C754D5D7A1111111111111137567B97C988788AB322I1IDGIAAB4488A899B99A8ENWYC5C777769576753722D84A39AADADBDE8CCDCCECEEEACDFI457ADBBEEEDEEHM86666665666666665446MK6DMME4JEPDD55QS96467AC9B8ACIECEJDEDHCEEAEHBDB67866677A7666FJIFGCFFH9I8DDEFFFGIGF5FAHCHH5DCES99HNCFB2-TTD2225422AADG66591566654545563FGED885D9D8999A99A97AD-EFIEFFHIAK74MFFEJMEKMKEGEC66587HAABAFBBCCCCCCCC9576B97E223222223346446746655555534531468246997EADDEGD99AA9AA9ACCCB8AD9BD8B523668C87859798C87BB4B48A625346348789A67573636638722213635677373353AC19744353333332144343334523488BA8A63A386A7888786798879A8E879--74984222222A6B8759688D6BDA66-86666676888C966666977CDGGJB9979899999999999A558555653EDFEFFDCDDFD113224322698742D6D6456882576524473445446437BF9BCBGEBC9EFCC4BCC5444454343877F88887CADDE57C6976889444432A3774444--------o-E221261432265244242722533365C667A7872725 B9EJfWP-xPBAgheWbaWckuf*uvlRRNPOPjoeSVOTTSTLKIhek*uw**hapdbUTWWOJBEG4KF9KHPEH3FJBEFEOKCFFe*KbdjXRPRbMJZkjS6N*l*p*m*s*aXYUZeW*xP*U***1*j*UWYXvWc*nRYVYRpWM*coXgrZ**b*cRa*ek****wDQNE*8AEPI*up*a**QV****k --------------------------------1---------------------------------------------------------------------------------------------1------------------------------------------------ * f.37.1 ABC transporter transmembrane region
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fANbgvVgVXWQIINKNSMmuJvL**W5cYqJTMF*HNjOIRKNGYMEdKdUOQNc*NQQPMiONuaWQQRNRT*TQRMUze**LoeSUUWNPM --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.43.3 Translation proteins
[  79] 11-1-22-1211112---111---2111--112-1---------412---3115-----11111--1- B463w2A4444DC9**tZZ-ZNAA*sYYYYYYUVVV****5fca444438345BC65A22ra55*i*hn*E----1111-113---114432-3--2223f353*3557444444433333332---12--212-45565---*2IOY1dea11111111211223hV*8111211131211435331-252*99E9ENAQBAHEQZ957SScr99m555G744444445*2266666666666666377442-4-22-1---4D111111212211111111611GA111311231111111111112111211111211112-6B4433U43241w2II----1133-3-3--656--51---11311-26-74222232228BD3*4237T33366666655663-5555776384227JHQ547635c44J32333E2232232222222223723232422223333223222222223222222222245A3223223CJKFIg*MWWMBBCJ****PsFDCM4H42333R22G22L356I82353111K3222222223F532212141-662311--3231434213433*g132------------111--11-111322DI24773345534333R53344333333841-54322222222U4f8458566N6POA44-748466B5AA7BB54555666BYE**86565676666566557A4544444228BBBBB6777B622235857977754Ht2c222222222222222CBCKC2A232iSgkam*u**KRUYT2yf*2222222221222K4AAAAF43CC55C555544422221112332243111-1---1-111111-1-12111111211331----1--------2O53 3311B7E-P9C1HFrof*i********WXYhff***xlchefhUTPrl******lY***UXSACBAD97CCBBC9EA89A9BDDABCFFINEfTaGBCBBILUMIN-KMG*YqnlfiLKJBLNKfoHjM**m4nUtFMMHRGLUNFMMHGOGGcPiINZTiq7dNEKaDFnZfeS7956*87888P*****wEFdWTWB ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.43.1 CoA-dependent acyltransferases
[  80] -----1---------11-------2-----1------1-----32-21-----1-----1--1-2--- --------------1---------1------211-1-122---1------------------2--22--------------------1---------------111-1-1------12-----1--1-1---1111--2------2211-14----------1-121-1---------------------12------1----1--1-----------1-1---1--11----1----------1--111---------------------1--1--------------------------------------1----------121-----1-1-11-----1---1--111--22--------11-1-----2---------1--12----1--------------------11--1-----111--11---1----------2----------------------------1-----------------1----------------------11-------1--221------111----22-----1-1-1-2-------1----1111--31-1-1----11111--12-----1-1----------------------1-1----1----1-1---111--11---1--1--------32---------1-------------------------------------11-1-----------------------------------------------2--21----11----------1--1-----1--1---------111-1--111-------------1-----111------------------1---11----------------------1--1------1-----11--1----1---- 1--155o-HB5176668695866847654598A567998869A58757BCBA8D888778C951122211--13-2-13-3115-21-27B68G7D5757474597-H48**********************r**************************dy*****w********255-I5224271378433549A94 -----------------------1------------------------------------1-----------------1------------------1----------------------------------------------------------------------------- * a.7.1 Spectrin repeat
[  81] 55214353335344332243443272264451122231----13221976ABA2121--2-3221123 9Fd3C53499643358966-692286555558BABA8EFE1A8G442-3---4451-1--6865I459GH638553551-2A2122--5574-445---6B688D9B67--------------3254846236A8KKJQR---T3E67956C22111114327843HD9M1211111311116653344345644444335343433333666734455454--------I8211111111111111111112-1-11---------1----12-1-1323-1--1--2----2--3------2-13111-1211-------656352222222323324453443572161322864326-133---4-2392j44431111127AGE5539988B22222222225-99DAAAAD6E55A3367889999854677G86CBBBD5B2222222223417A86-------------122--1----------143132455362225225-222656633222276C8996--5546A231AC72D6-15677A4311-----222762FL955156372444263523316A56C5Xh251-1-------1-11-1-11142256769A46998386757777566DBA6687F668--15537------26222425445554A45-4344545453454445445267341133232424234344224243333231-399889989886---7-----4434E3K24----1-1-----3-511111-4-115687775B87747445A7822333223256DD75556569BDC44443443332121111988558844454454731-----------1------1------18--2111212694 DF44efd-N658B8EDAF8CCACDB98FF9BBDFGGAGFFAEDFAC8C9EHHMOAC9C9EEE8867343766767783686AA976778IHHAHBLB79A9EDAD92N************************9************y*******************cKSHLd***W3PHA*8C9C8eVUeEbNIFHFGEH -----1--------2----1----1-----------1-1---------------------------------------------1-------------------------------------------------------------------------------1-----3--1- * c.62.1 vWA-like
[  82] 442-1398DCGDEEAA12443426F778336D211---111112213212422111121212332--4 5899YB6ECCFC6Ap*oVV-V*EEnqVUVVVdzx*yp***6kDc799D9776LGGDHH33RTb8IKUSVTJ355533323A8A33345AA9E28772--AIDF9GECAD22222222222222346479644454BCCBA334B5533334822333333333526BA83433343344333FFFCC217K6ADDDDDCCEBECEDDC6B977ACEDAEE9D65666666D96999A8988999989A899B83656647242656666674576566666797867755555555555576676667667644455444464686C4445444444B38867656A763B554299878A47765483153D2BZQTg45445GCrYbHCBhWkdaDEDEDEEDEBE-GIRGHZGLFLs3KFEHFEKLGLIKPPIZNLLWFDGFGLT44444444G5445GIE111111111111111211111111112114SOWK5BgXMfOIIKMPLJIIIFEVUKKKKDKdLichok48MMLICFNMVOYXXRB9M3353I95454443334GHMCZKHB9A947A8793GJGIK9GFKNLHNVQAA887324454444444444443553833IJ9IRGOGNOHQSUUSOVbTRSTRRZURXT2-46A74232222ECCC8ECDFFFDCCBDD-FDEDBCBDBDFBEBBDABGDEDFCDCCCDBBCCCCCBCBCBBCJBBBBBBB51DCCCCCBACCCC222G8888889887PNEI5557A8577765887OOQQOINCDBGDgfghSZTVTRPTSQKLO8444454444FFFMCCCBBGGMFFJIDFFEECCC67772248JHIJMM--------415-----------1---------1---56444242322B6A 4121HJE-K773BAHRUXNiaUbmckfUVRRQSLOLLOMOGMORQPOWLPUPcRLNQFKLKKNJNDDC7NBALFKAB88BFKLMPP678KTJUTSQFHFDCHLWfX2JnG*LVLMVJEHEGFIGVSDXIy*Y2ZPaBGGDLEHQCCGEJBKGANDKGFIKRQHvJ69GBDDNUJh8GF9yDDBFGmTfuTWd9CIMOND ---1---1-------------------------------------------------------------------------------------------------------------------2-----------------------------------------------1--- * d.38.1 Thioesterase/thiol ester dehydrase-isomerase
[  83] ------------------1-11----------------11111-------1-1-------------35 IG8BG1112221119IGHH-HZ77VBHJIHIFONQPCMGFEKGi*3131---756111--HG5-K7R9A84----1----L28BGSBC-----1-------1233-31----------------221313111D2QWWIG111Y4zTVPOO346HH--141-EPC2HHSH-2-----2----bEFA6A929C3888886784888888-44433887487H3KN444444BD11111111111111111111-225--8----3311-3-12111-----------------------------------------------6DD9N999A9A9D8F5YBC6566B6B--8GG9DKHIE976B99336821-E8E8EE7111113C*jgB9MhVSeh4799489789I-icoZbTbiBi82YWWYv*z***inYJ8JD3B3GGDEBHG11111111FII71tKc11222111111111111111111-11211-9AJD3EEC73NIJJLMHABB9GGXfDCDD5BOVVLZTU-3RQNjNhMQg4AtE8YZgXMYbeS-------88HRqx9YYNOOUWHybSRS2OJPkLSIZVAABAWXBFPA99-111114-1-------dMVUI43ieLjnhpVwVl*vuuromiqpnZolibZ*z---FeMl------FKKD7N9JIIIJJJIKG-GJIKIEEIHIHIIHJJIIIIMHIJ1-1C6BDBCCCCCBCCCDBFDCB86BF3-F56666655666--1Y12111MOOOGF*Ks---------------A9ABA59-4-NjWVWWbddcmYXWXZYZc-----3---ZWddVdccbagiez*STUUTURMMQ3333--u5ccGFaa11111111J2E------1---1-----1---1----H95IHABABB-5-- 9867C8N-RB*3BBK212-1111111111-111111111111111111111212-1111112111111-11112131-21111111111112111211111217662AM**tpp*dfPQPNQVSqkPoS**XAfS*PTQOcOUYTLRMTJjPH*RQQWbPi*i*seRrTV*pomb-**6K366753-4B1-1IQJJKMA --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3---- * d.58.29 Nucleotide cyclase
[  84] 885368969888888567796A6A78853278334334233444655893344444475584847-34 8DB2PAAHDDG8765A666-6D22AQ666668GFGHAOQS5B8AGCA65787HJK97D2286JHGHOJHL554445554233A34232AAA93ADD---5E656H4J8M444444433433443555766559459A987111575766557556686777667569878463635563533GDA9A542C6FIIIIIHIJAJHJGIKFEFFDGHIF977EFB7KKKKLGOJ8BBBBBBBBBBBBBBGA98FCG67DL85BDAGH55GH8A6987C99778ECCC99A99A89A9999AFFFFGFGFGDDFG99B654999F8HCFYDDCCEDEICH6G87ADAA9J37185892HI7LJMACAB55AA4H443BCAA523335EDOCF97DGNDCBCECGBFFBEDP-BDICDNEDBQ65TJJNKLIXSMPRAG996GAJGJFKGA7AAAAAAAAJBBB568J2221111111113357343411331111224BL63CHHDMJKKRLJKMMMMJJRRNNNNFLPKaOSPM5AKKEEACEDHF8QEQ77D5955A989777774449BH5QW876AA5767772RIN7O6CA9AABABBES312423323315466666663132167B7ICE6E8DIDEBAAA8BHEDDABBDBBK93-46648331222LEMKIJCTPRYTXWXSS-OURSSSUSTRPZTSTTUTSbXYIJDGBUOTPSRTRSORPSPPSNMMENNNL82KJKKMLIIMLKL332533333566666CBKBABGFG7AB97AEGDFHHCF9D897R9IJIIFLKKCEGHGJLJL222222222599AICCCDCC9CDGEFGHFHGAAA555533CF55557743353443635----3-215-331122274123---597444C5544655 868GNGJ-iFC6CEDDKMMUTROSWRNHHIIHHJHFJKOKIMKHFILOJRPWVYQPHLGJMLJHJGEGAJGKHHHKJAIHEFGHHJDDDKiJKLQVHFHIIOCPPP2HaQoRSXXYeLPUNKNKlTFZKm*Y1VSoHKQQONMvTGLNJEJFEvQROLVLVhJbLOLoLW*VTaMDJDD*B8AFCSOWxOcXIMUZPJK --------------1------------------------------------------------------1--------------------------------------------------------------------------------------------------------- * c.124.1 NagB/RpiA/CoA transferase-like
[  85] --11121--------12-1-12--2112-2-121121-11112111----11111113233-1-1--- 111---1--------------1--12------2111-112-222--------------11-----1-1---1-------111-1121------1--1---1-----2-1---------------111111-211111-11111121111111--11------11--1111---------------11121---111111---1-1----1-----1133-------------------------------------------------------1-----------------------------------------------1---111111112-12-------1-1-----1211--1-2-11--111--11----------21113---111-1-------------------------111--1--1---1-1---11111-----------1---1-------1-----1----------------------1----------1---------1111-1-1-1--11------1------1----11----1-1-----3-1121-32-112111211111111111-11211-112-1---111111---------11112--11-1------111111-121111-11111-----1-2-------11211-1111111111-11111-1111111111111-------11111111111111111211-1111--1--------------------11111-2--111111-1111-11-------1---1------------------1--------1-------------------11---------1-11----------------------------------------11---------111 EADIiij1pOV5QNfVSUWVXUVRSOSTSPQMQQPMQLHMJNPMRRRTTSTRSSMQURUWXUQNPJNN9MLMLOLKQFNNMSSPPPTPVLSOSXYlQJSMFSRlon3**K**********************e*********************************q****q***DoYW*KLIQW****U**QT****e --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1- * g.50.1 FYVE/PHD zinc finger
[  86] ----------------------------2-----------------1---542-------------11 129-2--111----23222-22--4333333243332343-231-21-----1-1-1---531-235131-----------11-----1121-3112--39365A45-61111111111111112-C2C1-1L2613323---D-L68766F----112111111368AW-4-1---2----1---------------11-1-1111111---1--1-----1-------12-------------------1-----1---7-----------------------1--11112222122------------------------11-1----------1----1111-1-------121--------------1-C2111-----156553112222311111111111-22531521214-111-313223341231111-242311-----------1-1521-1--------1------------------11222-153312232252111122423333-33135554-13335222224114-25C3-1-2-111111111422-45622-5-1-3----1-13111--23227u-31--------1----------1---11132113253231114431--1112-1-1131---1--3--------11-11133-1---1--2-11311-1-3121111112-5--13--1------------------------112133333433---2---------114-1--------------111121-3---3322321412421221212---------13343222222-23222323224471111--A-443366111-11-1G---------------------------1----------254 1---39U-917187578956645B56933453345765553376357354888B35A76677466325111231112-1111413433565984963568294484-2j6**********************J*********************************czkvx****1*G22111239694965347837G -------------------------1----------------111-------------------------------------------------------------------------------------------------------------------------------2-- * d.169.1 C-type lectin-like
[  87] 333221ADIHHIHLKD2955453-K555A4D4532--1----21742221764-21121117442-56 DDR8jA7FEEH656LONJK-Kd99apJHJJJLXbceYi*z7TIfYIJB9IC8PKQFBE33IIODkDljdUD62224645245K33544456413121112D2C5R6F6611111111111111564353644465ADDEC333HAG85A5561145112331365FGEI82112232122228B788982E3HDDEDEAEG5DEDBCCH9BBCDAAB6436EF9BBBCBA9F69A9999A9AAA99A999AC71D3DH4C212GH66BCG5777E656645334457755555555656555555555555554334244468763C665866876698664343424524332164636454259677248D4JMFFH22222JHXOaE8FMKGKI789B8AA899G-KLMHMPHKEUN1QRRLaXUXabUYGO9KAECJDEGFH9J77777777EFE75ABG2231122222111111111111111212249OJA53A77DYTVXVVQPNPMWWRWTSST9OWPcIYSN15DEL7F7EDIEICKFBAB2757B65443444667E8776A333224451213DBB345444FGMLOT69612112222235544333343412545897CA997P9A596686B6866575675841-27754111111CI8D7BHKJJMKLLLJL-ILIILHKIHKIKJKKIKKELNIHHB95EGGCFEHFEHFCECCENDBCEEEH21A888888888881116332338778678MG33392412221135177A9D586C7M6LMPMBLJJDIIJIFKKK4223242223877A666568C989DCECECB8B9C666113A997778111111114231-11--31--111-11--43-----35432364547B96 3356oyF-QA6158Nuw*o*q*p****SSRPLNPLLROONLQPKOJxek*w***ozkfRTPQKHW9HGFHCHSBSJLGMMFOOOIMEDBo*XwThPURQIUEPMMU-BwX*JHBMIHDEDFEDBURBfF**M2ZQkIFDBLDESCADDDEBIEMESDGNGNA9QKHKHEQOAECMFMNG*FBAPRps**inyFJwoknL ---1---------------1---------------111-1----------------------------------------------------------------------------------------------------------------------------------1---- * b.35.1 GroES-like
[  88] 33335353455544545233325647744544224221112115334B2EH9A121213233342232 A4B2B6554443337EA88-8733C98888897666669B3B8J57744333685444--BC83Q5DIDI433333333266214212B88533332--49456G79552221122112111143244B646B3B22134224A3JAD4968132232532334859E6J2232243422323113213143G585887D467G937B34454A6765658745955455E663344433444433454544I224333242243DE36554453495754223442223233333234223353334443333266572232D4363333645141C888533294455S5JN2GA836G4T34583223383763341121354D6BA367554333333332336-5954965668358AA5986746AB6A4546844335436222222224533294233131222211R211112121222243A72387423342D768D9DA6898778BBEBB3G4975458127645425335A9754494346422235433654B5844D548533834352557668T662362Qa85341331111221221122113334455534F86537565C9I84787866678D686--12364--1---46G64556777768776-6749768768678886786A65546574534463452675645547576673-66664664554511U532333BADA45G5522224314121223543473233458867B65H565C767B6AE2122222213635E45465M66574474647443564522B244333311121111225112-3-222241134312222111157621333232C34 HN48*KX-*dgQRNlVNSQlJMIKONQLMKJEJEMHMLMKJJKIGNkjILPHQMFRPsdLTURLJFBG2kGALFHJg4ILEGHTGDHFS*aVNRdZTGHaCXDKX*5GlW*z*wqw*lbiaghi**Z*Y***C*s*XgXXzdi*jYijgZ*aZ*e**o*e**i****tQe*eZ*cFW*T*IIHWM*yh*UgeQP****b ---1-121-11111--1--1-1-11----------311111-2221-2311---11-2---221325-211111111-1--1-------11-----1-----1-1-------1-1------1----1-----------1----------1-1--------1-112---2-51111 * e.8.1 DNA/RNA polymerases
[  89] ------21----1--1---1----31121121-1------------21--11--1------2-1---- 312-O--31112-2QnhLL-Lr33niLLKLLLpqvrQHUb2RFr2-1211--3181-2--SI9-aAcbITB----1----1-2----1---1-1--1---1-2-2-311-111111-------1-------11--13321---D-B753772--1111132131-446B6-12----1----42411----173333368444435642366383431---1-11-----2-111111111111111-111------------------2---1-111----111--------------------------------------1-1-1111111-1---------1-1----1--21-1---1-------1-1-17553-----22IEC11-839A51111111-112-45A5586849A-344578A24333213932922234345---------22----1------------------------------6GJ7--11111222521333344253333-44263256--32121-3141523-----1-12---------2131212----1---------11-1---1--1-7Q1------111111----1--1------------2---1--------1-----1-11--1--1-1----------21----33--------3---------3-----------22-3------------------------------------------1111111112233-----------------------1--1--34432221-2--11---3----1-----1-2-----2-1-1-113333---2232--1-11--------------------------1----------------8--1---11-- 1---kt9-D542A9C************cdZfZa**zcgcechfbba********rx**hcdcK8B6544854B4A4534449AAGC323*******44597FOfsr-Bo********mcbmr*z**l*o***-*t*Xgje*bb*xLbZfb*gS*i*p*****j************5SID*AAAQe*******8EYTRXB ---------------------------------------------------------------------------------------------------------------------1----------------------------------------------------3---- * a.104.1 Cytochrome P450
[  90] 11-3-12411111115-21--114B4648989-223233333466356439653445354452112-- SLh3M668666868eOSJJ-JO77bQIHIII9PIGJ99995BAN64757753998347227AB4B65COG61------12523AA8EEYacU2b8E2--BbESKmSiKP222222233222228A48AAC88AIC4444464442HIDCECC5466666C9A8E6UAGNA2622222622225654444498899A9A7CBCBABCAA5588B8BB8858B5A8646666FD46666666666666684668-222112-22222--11--2-3------------------------------------------------2E28F333333343423774557424224468466C66688242225484U9WZGGQ44444SZrhxeNdmgicXCEEGCGGCECI-ovZbsjnkCMW2cNNTRRTRRPJOOiIOQGCJDDDDCACKKKKKKKKFSPLIGTI44344444442242664764448745245688JKAFGCCPYgigiVOHGGFWVbeNNNNGPbShVhfp3CfgaJbOKPoZRIOIOYZOVNQIL5544444MHSVabJSQDDEIDAISCC84IRCKMPRLKQROOcO6QK97668888898A8888888JC8CLKQOKCeaSlWaTEVacdaccqoccieYo*mqe2-4ROGO------IGFIDRGILMMIKKNII-HKKIIKLIGLJLJIIIIIJSUSIH9BDGDADGGFGGGCCHBEDPFBFEBGH5-LGGGGGGECGGH225P8A888CKIKfSXEI444456444344554IILMICN666PNVXXZXTZaVbbcRPNSU644444444PEPPSFGGGGNWaUUacUOXPOIMMDBBB78PHSTCGOP6666666684-----1-1-1231-222-1--22---654A988888KSE7 335533C-711-23133342342222222312223323332332331242323227322332242231222-22212-22233333-2144332242342414341-1W6*VRRUVFGECDHOGQN8RBn*Y2RMZCIGGKCIOF7GEEELE8VHJLNZ8Dc7eKH8FFElx*T8-547UAAC63A43J43365M5C5F -------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.35.1 Multidrug efflux transporter AcrB transmembrane domain
[  91] 66647647B665EB883676557769G6ABGFD6A464245363EB8E63BEC347668444325374 86B5JB9BCCA897GJIHH-HG44HKIHHIHGGMKNJBLJ8FGHD98A9647C9D697338AIFA8ICKGAA766FCB43A9232635EBAB6A577-1C6558D8GE33322223322333336A4A97A4668CJK**557F6l******NPCD877466fk7****F357457547466637LM3268F5AAA9A7BC9ACC88B79AA689ADCG998C8A65578DAD556665566665567656595668B778A567779C568755655676A5879886779678A66677778865777776558775556FB78C888AAA9C9996FE769699F669DC88NMJ9DF59CADC8B275B7DEACD5BC6O97GCB79BJECEF33333332336-CBAAGKDDA765999AECAC98BB69468659878647676777777767456AA431223333433222222322322223342A6D97BB969D9ACC9A7899DDAH99AA9DDGJACDB46DDAAABB7FFFFF9G6B585BB99945646665ACA497BA45B6C3BA737AA7A8D6C9C78Ls9I5569445448765769697764576979799C9B87777D897679A88A87889774-5B36C243222BC678DDCFFCEEDEDA-FBEEECDDDBFCHCDDBCD9CBA978AEC9BBB9ACBBEDCBBF99A999A62B998BAA9AECC22B756545BD7CC5B5665797B47956C6557679878866A977B898ABBFFBBA89B677577767598BB88898AA89A8997998998876744A75555564C773333876A5E65-45435644444652133326A458445444855 9666TGA-LB64A8HBHDDDF9CCHDCCBF9ACEGCCE9GBDFFBEDIDHJFHJEFFGBFDA8A6C8639988978938787879A7BA8E7H9BFDCB78G8JCB6CF6******xpebcg*m**e*f**z9*z*Sifc*ii*lQraic*gW*c*gduOpWR*foUeXa****Q89AB*HBHABJEBeFQGECFQHD8 ---1-11---111--12--1---11----------112--11111---2-1-----11----1-11--1---------1-----1----11-----1-----21--------1--------1-1--1-11111----11111---1--1----1111-----1-------1112- * c.52.1 Restriction endonuclease-like
[  92] 44252367CCCBCCC65E666665D33E8BA4655445545479547557889578676383237-58 DDu8P89BHHJ889BECBB-BG66DGBBBBBDEGGHCKXVEDAHaZT89IEBTUUBCG44HEDALCMLYLA87779874586C99978EDME7R773557G7ENNBiBX555555575655555A99987999E9CDDUT666DABCCEBC9BBBBAAAAA9AD9BDDHE7B88988A9889DB877CC8C9BFFGFGBCF8EDFBCDQHDDBFFEB9FHAHBCDDDDDCFl9889999799AA87959656973379365529D4589567865B9955574448578778987878733334232222328566656667BB69F9998989A998B877764GA933A8988BC68879667CACB527CBiHEED57867E8GEG768A6A87LLJIKHIIJJK-GFEFGAGGKY76aUVMXXcefdZXB9AA7ENEGEEFLFH77777777EEGA9687443555554433222222222222244445ADH9889888FFEFFGFAAABEEHKDDDCBDGFHCEHC55DBBJA7C9BBDCBI9898879CA87887886868AF499979AA8987778AB9BB8CCGDBBD9A9E997688888999987777777789977DCFDADBAGFEBEDDEBDCDCCBBBCDCDD3269969755777IJDGEICIIIFIHHHII-IIHIKHLIIHIHJGIIJJISRRIJJEDGHDDFFEEFHEEIEDDOFEEFFGH94EFFFGGGEGGGF657855555889898GCO878A7A77776988A5556555779NDCCBCEFBHDEEHHEFCE7333254337CEEIFFFFFGGEHHBCDCDCCACC777755B799776622222222437111-2-1111241333112112---5A875BBDCC8YA7 433298A-J8847BGGEHEJHJHQMRGDDAC9ABAB8A8A89B9AAEBERGLbKIGIFEEFE7B88D9868BB7ADA8AB98888AFCELWFEIJPWLPEBCCFDH3DTA*ceWgiPKQGMNYL**QxG**o3*fwGTFM*MOiS9OQNGVDDePVJMiDIPIUX8IVKGpNce8GCEE*A9AFEnRjlHVRLLOVKLL -------------------1----------1------------------------------------------------------------------------------1-----------------------------------1----------------------------- * d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
[  93] --2----1222222111121111-111213-3--1-----2211--12-23311-1--------1-23 25E3D6664354559A966-645595666668556658B9466763124ID777923A11A872J6LDKL711111111111712222899A19652--45422F63561111111111111122112212323153356444B6V5FF66E3333333433246A668Q4322223A2224B643322453433333443334436422445543412445221221125739A7679799889994644341111111111111111111324122111111121122122113233111111111111112211122213113522222121136333222243711612323346433244333211253J688C343348AFELC74ADA8G33333334333-CBFAAH9D4C517448ED9DEE37748568938C999594444444424444H881111111111112212222222222111125326322222644554856657746767765686567422665CCFA75766433594655631111111446597S43231374744451475574353ABDAcc371221111111111111111131132334338249465376886776776755668691-2535611-11144443554445444544-44444444464444444444444433244344444444444444444434541544446545444113622222322254C2222222222221222222232222233644743439435574437---------135477666655477AB638336567645--53445555111313335331111-----1-2-434---13-22211111111115876 31--673-B51-75A44775364834744558A8CD94454446654468AADC65556344723111121222211111---2143222464545-1-1111655-2*L**********************1************o******y*********wq*******AC*P5NOA*766dHGegW7LHHcbslpE ----------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------51- * b.47.1 Trypsin-like serine proteases
[  94] 33111-5865565764-4242221C56543842122223222344336246772-2113114461-13 9CE7SB6AEEJ769OTPCF-ES44MhCCCCCIXWcZQY**BQ9fAB8A4B76YNWFCF--HJZ6IHXRQSE53335651144I33333324524224112B5A9D6C99----------1111254444535444899AA223A59AC9A9958443335556676AA96333333333343C9A8A234FCBEEEEEAEFBEDDBBBHGEE9DEEFCLKIHB8777776G74777777777777779997842325724222584455131364544444433335533333333333344344444444452244422242557F666766776737885554B66316463399474232236423135D4BMHHC22222G9JEO769DFCEDHIJOHFJEJIK179F75O8ETXD-RNNPOPcYScXXGGEE7IObHEFGFNQGFGGGGGGDGE86B8B11121111----1111-1111-11-1111BCTgD4FUOGJjfiffjWPPPKgfjnVVSREU*b*RicP36JFIHDFDBKHRFQX5692334F84766666374FGB89A39557757447-5557658986666FI77434555433322311121115233365EC5BC6QAJFEEEFEECEFCCCFDBEFFEI11-7653111111GCBB9CAGEEEGEDEIH-EHFIEEEIDHEEHGGFGGFPSPDCGH8HFEFGEFFFHDFHFFDNCC7AABC5189A9BBA8BCBB111844233AAAB49HNd565455-22224547QQRNOBJAFCL4QPQQQVVaJXYTTENLM6332243334988E9AAAAEGBCEBCCDDDB88822222233663333--------233----1---1-12-111-13--122112312222429749 --35CEF-JB81FICLOURYUWOafZbGHFFGFJIJJHIGGHHGGHJHQabq**TRLGFIKKJDF8ED7FCBGCDFC7CBBDCBEH99BRhUOJNKIGHBENLHEI-CdErZsWZWXKJKDKNLWaIoJ**V-bWoHKKFXNJYICLIHHMIDgGNKJVPkdGgNPLhFLREVXG9ED7*989CFaPqqUT*GDdOeTP -------------------1----------------------------------------------------------------------------------------------------------------------------------1-1---------------------- * c.82.1 ALDH-like
[  95] 22-1--97DEFFEFFB2A31-21264486C842-22422232343-2237999323322248863-22 MOg4i2243334237A9AA-A922CBA9AAA6B889D9IE9BDCDNA36633BBI634--HGF5M7IRSCE35554441121C45765dZ*p3c7821-Ab399wLf5*55555554455555698476658647ABBDD121I6ADACCC93488767788486BGHL8272333273253454339847464444457935547757A99794463657444B9BBAA8x22222232222222233232D3615613424BB444534544365732355554339998899999A45544444444443553335552G55E94445454645Y8665ACCT3U4247636457373H75688EI23475FEAA932222AAEBEIA65856855554454556-DD9CDAAA8G83CBBEHFFKKGFD466873344745112444444446884442611122111111111-1121111121211232875368776PMNKLLGKKKEEELJRQPPANKJNCFDD35A9DB7C665A99E64689977B4254543487B848996A45562935553EAF866ABACDCCBUA9263453433232233233224355676AB5A6NC6K84G666866998D6C68A69B2-3C777321222CC8A5B6BHIBBCCCDB-DBCDCBCDDBFBDDCBDD8BD9BA677BEBBBABBBBB9B9B97777899A61B8A8AA98A9A9117634234876795J8C65535443333333566656442338LBAAAACAF5B9BB5CBA44634533468CDL78898IEDFIEETTUSRJLH867623439944353333222263621111--23142111133123211138745656685mB4 6825WTL-C656CEMmc*u*rvj*u*sLKQNMNVRRJKIIMLJJJKvmi*wu**mrrpfifgKFSFEF3IFELCDHC4FGBJKILHAB9VofcqwfGIIHJVNVZh3MWWidZTeXdSPOIOSM*zM*L**iBnbzLOOQdNQfNIRQJK*IEcMZMSOPk*GeeOHZFVhTPWBFCH4i689KR*u*****87QMKNI -------------------------------------------------------------------------------------------1------------------------------------------------------------------------1---------- * a.102.1 Six-hairpin glycosidases
[  96] -----------------------DZ89J4SPJ--22-133234IY-GY7KH6B-1-1111-------5 EYw5L3343335438AB66-6D3389666655CBCC8BCA8FEKF953366478B234--DDP2O5CMIJA122343364E69-3521LMeI-T433--6M5CDoOmbd-----------1-1-7529747D8I6jhfdbF56r4*ex*bbGIHEE233786PcDW***N252322252332RF955242D8FHHKGKIEGCIHLMMGFEBABBJKP7BDG8BA865666aR55555555555555553354324266222-35533453334323544443244421-----1-----333332223323323322132335I8CVDFDDFFFFDG8OJI6797D7F21E88H4MOI9B743751136123W6Xkbba45557JMehjKGJZXQSY999B998898C-jgzecglqGPT4KNOTUTLaeUIMORPFTG8HIJIHALBAAAAAAAAC98B9*XX11112111225A2133332223333111228MMC7AFDAFVRUUdSYFHIGSRegLKLNBMaViOQSN26IJGlTZFHccVVV9GISCF9CVG111212187HJb*UugJGGjV8*ZXXc2*k*pkviJZus*v**Eh35352111111332332433CB43A55PKBYQXN8QMEODJJGCKKIJGFJGGLGML--4DFIE------EFECGGAEGFFEFDEEE-FECEEEEEDDFEEDEEEEDFIF9DAB7EEEEDEEDDEDCEDEEIDDBDCDE6-GEEDEFFBCEEE--474444456559HmDR444313121122113ACAAC6B579KPabjaTlbfVcdfdccTW2111-21-1DEFFKMNNNNLNQOPWZYZbZXPSS98781-*2YXCFLM2112122221--------------------------38132534543*39 ----BB1------1KDFFF9ACBB7A744332345544444454448B99CD8D7B856667421----2--221------22212322654F2A1678794645A-91711------------------2----1-1-----11-----------1-8----31-----2--31-755S12223h47NKCK82H2422 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------2- * a.30.2 Homodimeric domain of signal transducing histidine kinase
[  97] 55425753444444565356687EB88ADDCDAHGDDBCBBCCDACDECCIFGD4643443654A178 CDFCCAB98989EBC9987-89668D888887A898B9EDABB89BE8A878DFG97844AADAEFDDEED8AA99A959DEE689A9EEHI8I66-424C3BAA9CA8-11111112122221AC8CCA8ACAA99999AB997CDDDDDHECBBBA8AACGG7DDDFDAABABBBABAABCBC9AAA4AHHGGHHHGFIFIHIHHHHFJJFEHIJGGGFFB8CDDDDDGFACCCBBCCCCCCCBBEDDAF8435885A482A95599264687879555555598888888888888333333333333389AAA9AAA7EI8CIEEEEEDEDEDEADDDAA9HAC55BACFGKIELLGG7IEBBAE44A7BEEIID255157AEDE688CAA9AFFFEEFFDFFD-CCCBBCBD9D72HEECBCFBBDFGDB6AB69C99AAA88A9AAAAAAABBA8BBD11--1-----22111111111111111113BACA7BEEDBEEEEEEGECCBCCGDFFFFBEEEJDGFE9BAADEFFDDFDKEBBEDGDF9BBCCCAABAA88CECE5IMDHFMIEJGJJG5FEECDDDHGHHJHCIBO8BBAA99999A4A55555559H999AAMNJLGHP9NOFNNMNNPOONNNNONMOMQM-24EFFE542555NLMNLNLMMMMMMLMMM-MMJMMMMMMNMMMMMMMMNPQNNNLLKMMNONNNOOONNNNONNMMMMLMMG1OKHNNMMNNNOO567C333336666ACHCGHCHHCH6FFFAGCCHEFFEFEE788FGMMMMNKNOONOLMIMNLA5565A765DKNOPOPOPPNNONNGGFFFFFEEFEEEE77C69888A6--------1-5----1---1---1----1-------85676A8A9B7D52 ---1227-42-199FCDB99DBCDEE9BB9B9CBAA8B99AA9ABB8ADFEFIFEDBBCA8BC9C8888988889997998999996989F7DBAB7779658JGM-Ef5BEF9AE74323775A86E7P*D-E983772A48A638645762E6CC8E45234543572H33F5JKMM*JOHJL*oz*B*XKIWRSOO ------------------1---------------1-------------------------------------------------------------------------------------------------------------------------------------------- * d.58.18 ACT-like
[  98] 33----A56667A968-3613--4SDEH58OC------111-137-4-11966---1----211--Da 8LC2977888847495844-48118244444473C6ARKM365715545111E4F141119AD446788A41111111----55-5-3------------B1H743B54--------------11----1-----ACC57---AD5BF6DD335444537858318CA7B32223225322365152---G356666666326396826755556576AEB625111211EC31114111111111126351-2413315223432233-23333-3--------2--11111111111-------------1-----------12344431111----------1-1--6----11--2-------1----8-6955I111116HKHTKBNA887A9999989899G1DHFBLLEANEA1B99FKFTF9CKLBd488K27585965K5555555566645632111111111122212222222222211111A7AB-2A98EFCCCCF7EDDDGG8DJKJJAHDHG8CAJ11HNIO96F9CE93A4IC38845873434323NTI9664--3-341-31558-DB96FA631ECMBDX-3-114-333333---------31-5A44626C7A49594668779B3B875C64688C111G6-81111118A7A4779998988B88-9B9788878B989889888A7A4477877777777777877777876777851777777777778111B141115988BA815666635333333396744771433388CCCCGDE8GIJIIG97C311111111D21191111175767A777777888777744--775555--------1------1----------------------------1-9D-3 87-155S-fIG9MPSmSkUSMTJenWZJJGLKLQPTCGFFECFKHImcXeqos*RW*XOfdeCCBDDC6AC-A88BC3CBEEIFBB445RY*S*OsGIIH8dJMKK14*H***x***momejzs**mxm***G*p*moyo*px**ixngk*iV*v*vxp***Nk*JQjYZ*EHbK1qeI*545UJ****n**3Cffv*S -----------------------3------------------------------------------------------------------------------------------------------------------------------------------------------- * b.6.1 Cupredoxins
[  99] 443485B4CFEGBCEMI9KL958G757498544341B236582A53IJ42I8D6967BC4A3236231 9AE6DBA8889779E8889-8966AD8888897999A89E6CEHDG8A98889B966722CBC6DBB9E89B888A9B77CG89ABFA96DB3K4341-6545486HB633333333353333944989D26C256MJbh756B97BHJDFG8667944665CD6D6B65344454444443A7BDI994699IKIKLGMMDJLJJJMG9DD89HJME87A8CE877779DGBBE8B88888AAB8889E89B5665565545BB4566558654977BCAA788BA8AAAABBBABAB8888888889888B886668686EGA7DBBBCCCCHCI9BIH99A9AA8348FD7BHHEGEJ8DHDBDGG678AKDA878355459797A879AH9AF55555555557-BC89CAFAA972CCB9FDAFAA9B7867878A6655766AAAAAAAA8874A9AF333222222235548864A8445553333377B968A988EGGGGCD9999AAAACABAADCEBAAED87CCBDGBEBGFDCGACCGCA99BB9898888C9BIDE9EEA97JAAD99983IHMEGCTGHCCECCLCD64355443444344333334457EBCBECFDEABAA9GBCDCADECBACCFFCDCEF2-6EEDC112111BCB8EBCDCCDDDEDEE-CDDEDDDEEFCEDDDDDDFFGEBFFFFDBECCEDDCDDBDBCHBCCCCCCDB1CAAABAAAACBA2258AAAAAEJHGE9FADB9BBDA9BB7BDCCACAA9D98888CBDDCE9CECBEAABDAFB4555545557ECBFDDDEDFEFGECABCBDBBBB565665C46666873444344353422222---2-211----111--11149435688858674 8645LOD-bDO966CCAMIJ9FILJINFBCDHHDIDJFAFAEDECFICDJKJLOEFIGGGDF887667277686688698765676BBAFSIAGDI88897AAEDE3GhF*TW*UbTRSTOScP*yOmS**g5oaxTQUQkOQXUKVLUIbPM*VWIQRIFRTVVKHRGFVHPmKALOI*IHFJEQWToEnZDKSUUWM ---------1---------1---------------121------------------------1---1-------------------------------------------------------------------------------------------------------1---- * d.218.1 Nucleotidyltransferase
[ 100] --------------------1--6h56P6EGG--4-------1EI1AE2DJC7----2---111---1 FcW6a43678B333ELI77-7a22Ef777776dTUUQb**BTLm*D837553cTg646--BDQ3aQl**nH32224552241G78756334214--3---A164J9INB21111111112222154544267DG3*****544*J*gw*mmGPKNO545325QbIJ***U121111121221uN8A8AA5C7788A8AADD6DCDCACEC7787BDA6B9G6A6333333MF3555555555555556554342323323212222223222223333333222232233333333333222222222322233322233345G58GBAACBBC8B87966722244A219328EMIGEF7888B7767251J99F888-1111BEfTV64CVPPRFABBBABB9AAJ-XXYVPQVUNI51GKKNFIDKKLLJSHB667BMGCDE9GC66666666DDC66OFG------------11--111111111----26EM55BkdNZURRWSQMFFFBRRioHHJH8HcOuarna24LMCNPOEEZNUJZRBDE9AAAH72222222447MOM8fQH8FQ98PRFFD2gdgRebjJROQXQk*BN2--1-11--1-----1----12-2385ICEJ99GBMD8FHHHHEF8NKKFEGAEFIF---8JAD------BCJH9F7HEEFHFEEEF-EFHEGEHEFEEGFFGFGGFJKKED558C8CBCACBCDCACABBHB89BB9A5-956676665777---A22121654697EHG1112-2--1-11222889685C485KCNLHMFNMPEMNOSIOON111111111579ABBBBBABCBEG98MNLNMDFE222211I4XXJLPP--------71211111-1111111111111112111A87EA6D6765H15 2422322-C36-B7D7CCBAABCA7972222222221333233533CG77B79D4B5727684311112311322221232334342225A7C4636778786446-768OGNKMQOHHGFGGGncCLFw*R1RKbCDGDRDHXFBGDEALCCYFHGFO88I4DH98768U36HC-8A49--279OEGRBU79As*tq8 --------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------1--2- * d.110.2 GAF domain-like
[ 101] ----1-----------------------11------11-----12--1-11---------------1- aW*-1--------2-------1----------------211-11--------1---1---1--------------1-------36B67****-*IJ3--c*Xqd*P*d*-------1------1574866466UD----------F345331431--12-2-C72cGV6211-11----1-1-11-1-12-----1-1------11-1------1------1---------12-----1-1-1111--11---1--1----------2----1--1-------------------------------------------------1-----------1-----------2---1--111--3--------82l46****21111N9JAIEODOD8ID5655656656A-OKCJKGPM63C-AAB9657665ADI8*rW68W87BD344UQUUUUUUAUScA4gI1-121-------11-21111111111--1-b**nPFRLKKr****ygbacVwwwojlkgJc*i*brju24VTYGRMHI*FDFTFGkCJWEXNBAJHFIGHaEDFRM6FF85464515784-738CA4C9ID98BMW56M5N71744471778788567CE378GGJI6wD*xf*v5ltswtbjgruuhkgh*im*--4AIHC1--111cKGECPEIPQWKUTTMI-KKKLOMRKMOMSOJGIIHJVYZSSFHJKLFHKLLLKLKGKGIJOGHHHFIL41MIIJJNJJJIKI222I1111-3333AIIDMLEGBIA7AG968CHKYWYeWEg58Ko*imaiZuZkPcufSMWTQ---------AGMRWHIJHIVRQSV*******w**EEEE-152BB77FH-1111-1-2---------------------------1-1-2-----Ox2Y -111315-5-111-1412-1441242---11121--1212212---541242-2221-2-21212131-1141-21122113222-1-211113-31-211-3251-224J2244191---22261142Nj63423-1-21-224134-22214-13-L22249141143--1G4421-51----244g23121z111- -----------------------1----------------------------------------------------------------------------------------------------------------------------------------------------1-- * f.4.3 Porins
[ 102] 22-1-2112111-1--122----11--1--1--1----1-----2415--431-1-2----2-11-1- EQb6cBACCCBAABMJKNN-NQAARYNNNNNKSRQSQUXT8GAEHHGD8HC9GEC67H44HK99ODRedSA856557666A9A44444GFCC3B666--CLBGTOFR9P333333334333335665566557869AAGG-1-BERHINEFE8988698879CEA9GJMJ468555565565CAB67737CBLeekekmirUpfjknjPHOOKLknqHDCHK9ABAB99AjPA8AAA98778AA87A79BA6CCD9FG99FCCECBBGFA7D77D988CCCBAABBAA98898888998BCCCBCBBCDC9CM99FEB888A8IDEDBBBCFFDHCDFDGGAFFFGBBA8LDC88GFDEBB7F89DBE9378T84VLLQ46666CHTRPCC8HHGHGDDDGDBDACDI-GIKHIMGGEJF6KKKHGHFIIJJNDFEMSBECBAACADE66666666A9AA9A8D33111111--33789969A76688732324FEGLABDDAHMMNPQNJJKKIKKIHMMNMANUHEGKMI66HGH99DBCKBBEN9CC99B7AE8555555558AABEIACA74758897762ABBB97A9ABDBCMK8D6453644343534343363344536CCEF8CCCBBIBBEGGGEHDDFGGFGGBFGGC2-6595912-222JGCBFGFIJJKIJKJJI-HJKJJIIJGIHJLFIIIIHKJIACKIDGHGFGHGHHGFEHDFHLFFGGEFI74IEFFFGEEFEFF335H78767HKHE9CH99A89868698857768GEHGGBC8D9DCKJLJFJEIEFEFGEIGI66757776699CAICCCDCCEAFAMLC9B9A99797773277IIBBBB44444445842----2---1-11-----2-------45543233235BBC 5223FF8-F436436DHLEC9DAOIKG988887B97A97A99A578A5FOOMmSB9AE677862723424551-833-223562423233A6H48522251362B419cG*CFDIKDBA695ABJC8FBX*D1JBKB749978G68785AE7BC59CHJBHBBVDD9K6C7MTD84383D3431AK76JBBC61E738A --------------1----------------------1---------------------------------------------------1-1-111------1-------------------------------------------1-----------------------1---- * e.3.1 beta-lactamase/transpeptidase-like
[ 103] 44C5E49ADBBCCADF5623-1-9L99AE5D78A9AADCCCCBABADB89GFC776977776875-66 8Zz8K634557243JHHAA-AI22MeA9AAAHNIII9TVS7JCbJDA56863TFMC7A1199N6XEdMKS851119CCC7F7Q44444AA863D56---3C8IOa7UGM---------------22222421122CBBB9333AF8775776AB45223212346E7AA7131311132311A8D3377347FHHJHIGJJEGHLJHHQRBBADKGK8D7JKBD99A8A8YP677777777777777A4436L57557384646855AA845666444444644485466666666666666666665666684444444447NI7LHHIGGFIHFJAb886DD8HIBE2EA4D5WO8B896dEG9AB89D3X7FEOOR4444456qih437B88D6MMMOMNOPOOS-OJZHGTNQNQH2jRRVUSNhZRbeSJHQMITWGIHGMNQHFHHHHHHDJIGA5BC11222222226C-------------22225CK*IACHG8DMVXYWMFCCCCNNWQIHHHDEZHcNWWV-7EEGACA46H9JBVQ4F85768B6-------466A855ED685CD68766536844754346668KJ8B386333333336455555553324877JB4AA5YMCH5H8ED9HCQDBBAFCIHACM--18547------F5E9J8AHJKIHIIIII-HIDIKGHIKIHIJIIEIIAJKM77749D9BDDBDDDFCDDDDBF85666594-E9999999999A23-Q22222655578K6G222311122221113888687D195H9QPPQLPPLHIIHPAJII7333333335BHOV45445E6DJHFFADCDD9996555--4I774432232111112---------22-1--222-26-22111DJIJK6E666B656 ----CB3-953-556PBOKQFDBTONP7777679887676665656JCRTRbmiECE99GGE98625D4524C6685466665574355IWIBCKDAB8FC77FGA-BKBfQjKWVLDCHDGIHeTIZFl*M2VIgAHJGZFHIHEGHCBPHAWFSJHNDCQDJC8BDACaAEUC2AG2*233EAG7FGL6V51QEEEC ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.92.1 Composite domain of metallo-dependent hydrolases
[ 104] 88C878AA99999999CA999999C889BB988686668888A7678677CBC589788787886-56 99A6EBAACCC8B8A9FCC-EC55ABCCCCC9GDDDACBD9DEEDBA8AAE999AA9B66CECBD9GFCD9BBBBDCB999CB96988DACF5AA8322BC9ACBAACB1------1331111378959767787DDDGFAA9DFDBBAEED9BAA998B88A9ABHCFC88868888868ACBDFE99AABCDDCDECDECGDDDDDDBBBCCDCCAABDBCCDDDDDDCGCBBBBBBBBBBBBB8BBBBBDECDDDEEEGEFGDDDDBDDEEBEEEDDDDDCDFCCDDDDDDDDDDDCDDDDDDDDEDDDEDEDECCCDDBCEDGGGGGGGGFHECEBBBFFFCDA9AA9A98BBAC87AAA9AAAB9B9B7AA77E455559AC9998797A7889999898999288B99B88DCA5CAAAFEBBBBBB7676A8A9AEAAAA988888888B99886CA555555555511-132-523--33-445566C88787779ABBBBBB9AABDDBGBBBBADBBCDEFC77GFDC99D9ABBF977A8B888A8999AAA9889A87CAD9D99A8CA99969A9999989AAFAEEAA899988888886866666669999C9AA9B9A697A99AADB999A999B9BA9B994-8AA694425559FB9C99ABDAA9AC9B-BAA9AAA9A9B9999A99A9CB9ABEC9B99999999999999A9999999849CCCBCCCCDCC446A667769AACB8FACAAAAAA9CCBCA9AAAAABAAB998F7AABACAAAAFAEAFBCC87878978768BBA99999999A99888A888886666449B77667755565656865----5-556455555566856555697799898889C79 6622EFE-aDG5EEFGIHGJEGJLHIJFFFHEEGEDGEDFEDDHFFLHFFJIPIFIIKHJKKHHGGIHBGHLJJGNLGKLHEFGGFDFGBIDIECFCACBBGCNMZ-ETBXUeWNXLHDFCEHGLQHRE**N-QIfDCIGMCHRGDFHFGHDAZFSMHMCKODNEEDXBGDFQJBCFCC*CADCAQOuXHYKHAUNKMG -------2---------------1--------------------------------------------------------------------------------------------------------------------------------------------4---------- * c.61.1 PRTase-like
[ 105] 11---1-1111111111-2--11-9334-53211211-4232347212--C55-----1--------- BDJ4*87899A675*ywYY-YvAA**XZXXVg*w*w****5zN*TOC99GA5HJHF4P--XbP9*T****J24552442465A52443A9B51733---3I558mBMAG---------1----123-341324517A99E111W3R6BD8981411111-212619B9K5-121--21-11-839443239AYRSRSSOTVBQSQOMQLEMLHPRNQ7AEID46555455nV4433333433333333337373439833433664367662632688111112155422221222222111111111211131244422214CAFF7769767776G9FG355492521A3261NJ955688653465423B3HlJJH--1--PIlNVD57WHKLE6666656656G-CCIADLCA7aQ-WMMKRRHXYZJOLO7F88GEB6ABBGG888888887CD458CA-----------------------------14IEA24MGEOdeiceiLNNPMSSWWPPQPCXnKgRXUW13KIGB9E99RDOHRH5I58CAAD433322225359886qKP83894AE8891495D99E8A8BB8Wj6B3111-22211313-11-1113235822EB6AKCO7J77DDEDC9DCFDECDD9BCDE--11652------BDBB7E9BA9ECFEFCC-ADCDDDDBEFAECCDBCCCIOLBB9AC99899B9999999899EBC8AACC7-976888757888--172222235364EP9G422113123322223LLNKNDC664A8TTRTGbSWJKKIGBWST1--------399AGABACBCCDAAEL9FAFE7563232--62EE89881112112-1141111---------111---------22332343331H23 EBBCkv3-M962FJ478IAABHEOIKNCGBDDFMGCCHJHJDCEEJFH8EBDLYCAJNCC694281241733315763834456A3311AI8879F31-424179B-4hUQBAjOFMEHLGG6HGEJJNn*81SEXGOPLBTEEBO9JNJ9ZNIXAA9*BCQDE7TNC32PKFC32FI7NH36D6OC8TC7A7EDGBAE --------------------------------------1-----------------------------------------------------1-----------------------------------------------------------------------------3---- * a.121.1 Tetracyclin repressor-like, C-terminal domain
[ 106] 442123344333433433886672E89AA9793531111111-3413413887211111125224-45 5685SC9ACCA868FEDBB-BH66IJBBBBBDGGFGMHLH7PNVGJDCADD9GFEDDC22OLDBTIKSRQG89AAAAA222792-222887A-A223--4B489H9H9B22222222222222779484444757BBBCD222I7C8A789734553332336969BAB8132211132222MDP88224989UTVRVTWYEVVXRVVDA7766WUW957HGJG9AA99AELA6666665666666586675957BDBB6679DE44DD563776DBC899ABA8C88AAA9A9A98897677677777768FCDABADDD938B9A888678777768446BDAD5543H9F115623423222435415854CEHHE3333389IML968FGEGEAABBACBBABE-FEDEICFIECD3LKKILJHJJLFE9C9D9DCAB9BBDCFAAAAAAAA8AA66BC9----------23323313331122111111A98639979AEJJIJGEBBBBIIFHEFEECEKIJCEBD98CCG8BDCBDDC9F98BC8766H85666666778E9A6775559447345547C77B88A98888FFA7732222222222223433332343444JIDBAC99DAGA9AA879AAAAA8BA9A882-6A98B2--222FIIGHHEGIIGGGGGGF-IGGHGHIGGHIGGGGGGGHHHIGIIGEHFGGHGGGGHGGGGGGKFEEGGGGA-EEEEFFEEEEEE12397645568688CICEAAAA8A577676669CDCBDCD777CDHHIHGKFJEGFFFCEII5553454555ACCEEDFEDIFGFIECDDDDDBCE777731A4555688---1--1-31711111-----1-------1------46353242324686 4333NNJ-NB8ACDGDGKEFHGGLIMGBB9CCDBBBACCDCCC99BGEIKIGJMCGIEEHGGA99687587786A7746779889B9BADPKGKIHBDDDCCELIO2L*XkTZUTaTNJMIKTMtfHfR**h2XUgINOLXKQTTJOLJETGFXRPOLTIIFLWMNFOFEFIHSKHQKE*KIFKNOQYwIfKNQRLJEJ ----------1111-----1---------------12--1-------------------------------------------------------------1-----------------------------------1--1-------------111-------------41--- * d.113.1 Nudix
[ 107] KK5GCLRCHGFGFGGM88KGLJIFJDDGAGJHFCOHJIKLKKKNRFPKHMLNNFBBABABCAA9926G 6A82E64BBBB5878AACC-CD33DBCCCCC7FGGGCACB8BAEA984B885BAA68811EEB6AEJKSLC32223545374C67B9A886729341--6C78CB48C955555554445555599877989789FGGHI4457AQFIHCDCA8CC877666E98ANNKE464434594455656CB4436BECCCCCCCDDCDCDCDBAFEBFCCD9DBBFCAA99AAAEA9666556666666656677794448843534543388844453544777544456644445444445444444444444484444344462GDBHBBBDCDDBB969IICBBB98775954ECHJGK7B8EAA65622558ABB99A555558AJDEEA9CCAB99989999889D-BEH99J8ADGA5JFFDGEJJFDIKBB898A6GA8AA779666666669CC65ICD33433333333334344333343344544266A85A9989JEFEFHEBAA9HHFLDDDD6DGIFBHBG57DDAB7ECDEBAHE89CHDBABID4454544898FDH8LNIEJQH9SLIFF5BD9B9AAB7MLRNHN8K642243322341311111126743677GG6CDADACFCGFGGGAKIEDDGHFGCGFK1-6DNDC221333FA887CABCBCBCBBBA-ABABDBDBDBACECBBCCBDDD899A9BCBBAABAAABABABACB9AAAAB63B999999A8999344855545887A8AIFD3333443333225557777778879A8GFGGCADCDEDDEAA9A776757757CEHFEFFFFGGKHGHBA9AABA898544476H67777BB3334334365411111-2112211222-1112222266766B7BAB3B84 1311bbP-TEA8FGTADFEDBCCEBBCBABBCBBB9DCBC9DGAABAABBCEEGACCAEBCBBAAAC73B95C9DDC8CC8AADFD789BJCDICGC9BA9ECQSU-KaMTWXNaQSHJFIELDgYFOG**T2RNeBFFCRFGHH9HJB7RBCPHSDHIGNPMKDH8f8FMUaFCEMQP*HFHIK*gt*CifIMRZYcG ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.37.1 CBS-domain pair
[ 108] --1--11------------1---26----313-1------1-175-3K-5K13--------------3 BKR2452A4451-117733-35222353454283343A63123-2--23237557233--715-638865-72218D3-495154558GIKM-D-----2K4C1LOL4F-------111----24429V728DF366588748C3U38I674131121-4116536GGOA111111121111544111126A8GGIGIKMLDKJILKN5EBB79IJM578C1E8645634LM321---------2--333216235345222222446511214242955463733245555557555543543467466543112211113ASIEbIHGJKGLCLA7EII8998EDJ46DAG74MHCK8D1566656C1-3GL7G3394444255XDFG65BLCDE33332333327-GAG9B9KH1G81EBAEE7Q989IBAC3337779N886C377777777EGC14B6A3332111211-11222118421111111-224N5246559LKKLFMOCABAaQVTEFEE8DEXcHJJR-3KHIDABH5LIGGL6DHW8696863443332344lANA*kKBDND5NdHFN3kWujdTeCWGEFGOJDKT4886333325222322122HK9AEBE6J7DaBL6L9AFqGHH7HBKEFGIJFFFNJ--23769-1----A65A586CDEHCGKHJC-DCCCBDDACBDHCBBCBBA98A87954DBACCEBDDBDFEECFAAD9GABZ6-5qggE*dtY8G8---72222258564AN4F1--322-111132357776755684D9CAADHHLM6GGKHLhUN11111121137B9HDDCDDMIDGGE889A9B9894434-1E5JJBBFD221222222-2--------1--------16-1----3G845353234I12 3255455-7485A7G98B5C54A787745654534537268476577CBBD9ED9A369578742536-65664424-2143366722D7I58A7685442FK58Q-77Ngjko*qttnbte*w**l*n***5***mmmq*en**YmnbZ*TU*T*eV*5BP9LDCECEHR7OGA12416213-3WDJSCOI23FCDP5 -----------------------------------------1-----------------------------------------11------------------1---1---------------------------------------1----------------------1--1- * a.26.1 4-helical cytokines
[ 109] --1-123112311111111121111--1--------2-------1--1-2333-121-111---2-11 1222611-222-2111211-12--1211111133332A46-43421---232312--3--431-2124342-111---113211-1--222--2-----1-2--221----------------2-----1-----23343---223123--111321--1--1--22311--------1-1-212-1------111111211212112----1-112---111122222314--------------------13542241434333322323--22------------11121-41111--------------------------1111-11111111211-221-1-1----1-1--121--2111-1----134223-1----12212-122213----------4-34343323--11132112----432-222-21-1-1-11222222222111211-----1-------------------------2341---------1---------12-----12123211-1--13121121------2----11-------11--2-32133111-31111--1-11-12212323512--1--11111-----1---1-----121213-1111211222223332241222521---1-33-------141--11111111221-11122--111111111111111211111-111111-11111121111---1--355545445343--1------1111-14-2----3----------2222222--1--22222222411-1221----------21112111111211122-3232---11-11--211-------------------------------------11---1---11---1-- 4588nk*-wQQCHIRDHGEDEGHEGDGGGFJIGGGHEGFGCGGEHIGGJFEEIFDDGFBEFFHHKIGIFHHLIIHHG9EGGIIIGJBAAOaLHJNOHIHGAFJVUT1a*o**********************F*********************************g*ko****oBPO9*9A8HLYPcbFYfBHekjhZ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--- * c.45.1 (Phosphotyrosine protein) phosphatases II
[ 110] 554242888999888656878632A66874A8235243234232432416665365544466443-55 5AC7F96BBBB884BJF99-9G44FQA9AAAEJFHFCKYa5EDD8A746996IEGEBA33BBE688HGLIB42223337354954535A86836666--4A54696D6533344432333333475478736586DEEDC224BCGFDE88A88444546355B8BGBAA634365655388BBB9953586599999B9B6A9ABBA7677559A96787855766665CB4555555555555555444465355544566774486533545434665555548744444545444445556767444563433433354779C8888899B9C66779A9A7B65677788BB7C666D585545665969HGGE26646GCMHJCBCJIHFGCCCCCCCCCAE-EDMBFSGIIOB2EAAJEFNJFFECICD96FEGBBBADAF76777777E884CABD22121111114F122211111111111116ADHD7FTODLNIKMLMKFFGFIJKOMKKLBJRLUKPOL6AKLJDGDGEKEKIKKAAGA8A8J79999999AABEBC9AD7757777699657798AAD9B9AA99D796545444454335433533424667CBFFG9C698CAFAGEEEDCBAA9CBCBCBBB4-4D9AC431444GEHFDEAHJKIHJIJHI-IIHIIIHHHGJIIIIGIIIHIJHIEFHKHJHKJKKJHKGKHHJEHFEEFGGA2DFFFGFEFFHFG335A67678A89A79CEC455666565666557888987B678L6IIJHIMHIEFFIHFDDH7655555566BECFHGIJHDFEEEABCBBBBCBB768644A68A88BB3334354491433314-345334433334633422228654644458768 C753JB9-S9A6CFFEBFDJLLENMPIFDFE9BBDABDDEEDDC97EGFNJKYYHCCFCGCF85775646A5545964B8566555355APEBECACBBB998BEG3EUCSOPQHPMFBD9EJGXt7e5**T2aOf6E8AVDGJF6G868IC7W8NDAM8C59DPB8I88IGTG9FOXJ*BEAIH*b**9tUOPOKSgM ----------------------------------1----------1----------------------------------------------1-----------------------------------------------------------------------------1---- * c.1.12 Phosphoenolpyruvate/pyruvate domain
[ 111] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----11N-313-142222212132222111222222211111122222121-2-11112111122212221221211-11111121212-2222222222112222-232**********************A******************************************211-5-1-12442523--12335- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.12.1 LDL receptor-like module
[ 112] ---------------------------------------------------1---------------- ---------------------------------1-2----------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------4-------------------------------------------------------1----------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------2 ----314---1--12-----------------------------------1-----------------------1--------------------------------7i-**********************T*********************************e********-11------2--2-11----3--1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.23.1 Spermadhesin, CUB domain
[ 113] 33444355666655774764575A797756676596556655568476678A8644333437445-33 87B3E648998857IDDAA-AK55FOA9AAAANIIJIOjZ3D798465555468886D1176H7C6IFCB86555776328594435388884D331--48486M89561111111111111127559995558799978222B3IBB799B55885555448B46FFBA444655544547A896566277CAAAAAABA9AAAAAA7888BBAAC7898C878999A9GC599999A9AA999A9A87A97664AB4443678449984458685544463444556666556666655555555555666664446665679BDAAAABBC8B98BHH4675C6434877K7EBAA985F6888A6446C7AHAAA23333BAHFH867A89B88888888886A-99B98D8CBEG3ICCBDECEFFGGFEBB9ADG8988EEICCCCCCCC8A889C683353233343112222222122223334379EP759HDAHIJMJOOFFFFEGGMLHGGH8IQEPEHMD58FDHC9ABBJEFHFDA8A6788EA88776775558D8ALFCD9865AA88936869B7CD976678C67658534445433333333335444744CAABF6H8CB9BEGGE9FFBBBCCDDCCDE1-466461-11119ABB8BBBEECBDCCBB-DBBBCBCBDBDCDBBBBBCCDCDBCD8BBBCBBBBCACBCBCCC799AAA921988999988999--253433379A979ADC666769545546445FFEEG9FCBDHALLKLKIHOGMKJIEIEJ64666666478ABDABAA9CFF88BDA9A9988854443276DD67AA33333343823----1-1121---111122-1--1-27847656567754 4556HIG-TF86DDDTXTSZRTLjfkWFFEEEEEDDDECDFDCFGFQORYbm*rQSKIIJMJHJH9DE7JDFLBMEB89CHIIIGJ8FAL*SXMcOKHIFDHHQZS3CeQqAHAACC88968D9DA9M9e*I-KJN998CCB9KA7BC98B58C9DH9EEHPDXCDIJAENIPSB5HHG*DEECFdVjjObTMJkZo*Q ----------------1---------------------------------------------------------------------------------------------------------------------------------------------------------1-1-- * c.1.4 FMN-linked oxidoreductases
[ 114] -----------------------1-------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------1-----------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------- 3355TQC-O9D18ADQOcG67688A5A88BFDC897EEACEBD8BAOHEGFKGM8CGGICDFH34343143242533233355543455DkHOOWJ3456537IOH-L************************X*********************************o*******L4jR7P3358Hu***P*RBJBEBDC --------------------------------------------------------------------------------------------------------------------------------------------------------------------------31--- * d.42.1 POZ domain
[ 115] 22------134211---42112121---1------1--------1-1---2-----2131--1--2-- 7DV-712-----1-35422-23446222222222222322266722352222432222--BE23766666611111213444244444AFEC2C886--9G4KCEAJ8Q888888877888888666666667J6766AB22276FEBACCB4488444444AA8CEEKC4444655444448CD5523-67789899889978888898777B88A9787877555555967555555555555555557655455555445555655434644655555579744555555555555555555555555564556555546ECE9BBBBBBD9B7A7FFCA9A7B645A572233232246226677223O6B9DD92222266C6A6766666644462266247-97B6766686626224256775226764C776666676666666666266626A66676666666-122223243222226678-E96AA44444111--11------1----2----2888A44544266447444444484454544411111445544ABA87A8C8B9CC88B9C8988DAPQEUVM8G689695565545555555555565532DD5G88IC8G5LLMMKDDEKKKHHFGJIGI--28444------997A789BBBBBBBBBB-BBBBBB8BBCBBBBBBBBB999CD77A66666666667666677BB8988B5-DA999AA9A999--3C44444454545C7F777531544555555777777C999BGAA9A99886EEFD788844665444489CCHEFEEFEDGDD455555555544544-B36666669889A9995341-1-1---------------1----22362333245E8D IHk*NVJ-*LNCLJLLIMLINLILQJKKKJIIJLLMMJKJIKJKNPKNLMLLNwJJLQJLKLPOQPOPNNNORLPNPGLPONPMOZIKJLdFIGFIEFEFNLHVbT7V*kppmYdgaNMLKPRGimLvK**W5ZalENQORNPaIINROGRNIvOeTRSNfiVVNVWeTdyOzdKRMZN*RPPRTvbkjKqkadQXUSS -------1---------------------------------------------------------1--1-----------------------------------------------------------------------------------------------------2---- * d.185.1 LuxS/MPP-like metallohydrolase
[ 116] 22--9-51767769DLG5LQ6548-----3--213-92-1-1-3-1AD--917465479271--4--- 44C2U314447212L7755-5I228K555556LHHJTVeP-77OAI793341IB9323--ED51Q4LMRO2622244331B4234566ln*q-l544--B*AFJ*H*4p--------------1--334813781287QO---C3N6EE56B312274-513871E6NC-------------33469A614569AAA9A8D49CC8BBYODCADBAB697L4679BAB97Q*28877777777787656699A662--51334A91142126277334453654454444433344444354433543444474411-4442NJE6jKJKLONNCLAVNEE49A9x88643EP14XNA74B4778976S-25HBHPFFB-1111KHgTW534MEBLBDFFFDCEDFEM-GDIFGPDQIZB-rZZRcYgqsgXeIE6BFCHSB69DFIP6666666687A3585H------------1-44-3821-11------6Da829FB9Py****wcZZZQnnyzjijjGf*v*UbaR12NNOEBC75TBCBhJ6MA285AMA56555556438K83C3331643CG449-ABB785I796659GY-2B-3211111-1---------3637553KIHBOXS6OC6BIFFFF5FLDECFFFJBJT---5437------MIOMBNDJNNKKJLJOL-NKKNIJLJKLOKNMMIOMHckcPQEEFQSMPQOQONQPOSNPQQFGDFDEH6-JGGFGHDCHEEE--2712--165749GlLo33364A144336223PPQTRDP264KEknqkdzmwgdjkiPPLM1111111113HJLTEDDFDJRSLRMUFGFGF88712121152HI4698--------5-1-------------------------121-1213323K3B -----1-------4---1-1---11--------1-1-----------2--1111-1------1----1----2--------------1-------1111---1-------72334312111-1131141461111111-1--14111-1113-1-1118--4173--2--1--41-------1--I1251-1-16112- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.24.16 Nucleotidyltransferase substrate binding subunit/domain
[ 117] 33334334333333333343443463343332544323345543333455454645334444354343 ---1-112111--12--11-11---111111-111111-11---121-3---21111211-11212222121111---11-12-111-22-111--112---1-111111------1-12222112121111321--1--1111---1--1112--111121-1-1----11-1111111-1211--11-1-----------------1----------1-1---------1----------------------1----------------1----------------------------------------1---------1----111-11----21-------1-121--1-111-1--112--1111--1-211--1-211-1------1-2-----------------1-1------11----------11---------------------22----1111-----11--11--211112111------11--------------------------------1-------2------------1--1--1------------141---1---11111--11--2-1111111-111111111111111221122222-11--1-111-111111111111111111111111---111-111111111221-1111111111-1111111111111111111111--1111111--1---11111111111112-1111111111111-1-1-----1111-11--111-1-111111111----------1-1111---------1-1--11111111-1111-----111121-131211111-------------11111111--11-121---1--11----1----22211-111-121-1-- IHEE99e1W886NQPRQOPQRRPQNPPUUUYOVVUXSTNSOSSORSRQNQQRQQPUTSTPSPPKKMML8KMOJHKKMEJMNLLJLLQPJNXLQNOONMNNSMMZVa9QvE**********************9****************y**x******n***pk*j*zy***yk8OWp*dfdPQVo**S*YBSJPPQP ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.51.1 Eukaryotic type KH-domain (KH-domain type I)
[ 118] ----1---------1-------------1---------------------2-1--------------- --4-2-----2---------------------------------------------------------111---------1--1----112-----S--22---1-----------1------*-------------------3------------------------1-------------------------------------------------------26A3311-----------------------------1--22----------------------------------------------1--------------2-----1-1--1----111-1----------------1----------5----------------------------------------------------1------------------------------------------------11EC-2413-------2-1-----------------------------------------E-------------------------------------------------------------32----------------------------------1--2----------------2--1--------------------------------------------------1----------11111--11-1-11--------------------------11-1177A5-----------------------------------------1-11-------------------------------111---------1------11--------1------------1-----------------1---------- 3334**o-***JYW*GIHGGHHHDEFJGGHGBEEGDFDDDDFDCDEHGIHGGGGEGDHDFFCAB8AA91E9FB9CDA4B99CCDCE444L*JIdpdDAECOEAh*Q1***********wtp*****t*****7***g**w*****j**wq*ob***v**koNY**sX*hskKa*WD**W*GIFfP****G**izq**** --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.10.1 RNI-like
[ 119] 44----5353353553-222--12B44C75881-1--------16332-2545-11111112-2--36 9UY3i637CCD222XVKCC-Cd22TfCBCCCIhejfoj**2UDZJg9K4FH4VUTAAL--RbU3LIgjvc72---6313-32M--1--546515333--2I3BAY8P9K111111111111111212633233339BBFC---OLY9ADCBA8877237755983KDHSF212322221232FFD57111C4IYWbWbbZgGXcXZaWKMGEGKXWg778OMJOJMMLJIbbAGGFHEFEFFFFGFFI9AHOM-3-77-3---1144882323238DG9998333655465565575555455555665535A9A445899D2D4AA333776527569221222H1222C151-A9431-22212232132M-8RKKP----2CFtWWC79K6FFBGJFJGFHEFHQ-DHHHEUFNYlO-xVVPdgkwvhbhQPLIH7TSFBGGCHP444444444CC645E5----------------------------12DY*M3AIGCNWZcaWXPIJKGVVdWNNNN8JoPlVeZR12LOILKEIGRNS7eF9D95737O3-21222253C6MDB6431223184322-778475944BCHDNT453-1--1---1--1--------1--267IG3E68M7RF8EHEGEFECFEECCHBECHJ--17528------48C95844444444444-4446454434444444444KJGA97847476657676667667I44344433-433333333333--1G121127D9A55LAI3333242231222247778759154H6OPKOHGGHFFDJCFAA9211-1111127A9HJFGFFLJGGJPPEJHJJCCD22221161BA66AA--------3-8-----------------1-------11211-1---3K29 22--B99-94-137EABJAHFHCGDCE988A79AA7BFCDGED998556KAINO88ABD657336131123153432233144464223122B7152121134435-4Z8NDCHAAC85B8A97AA4B7K*A-A9H69B6A7CDB687488B5A77A8HAD77CAC6655769C9AD86V786ECTEGY6MHFCB753F ---------------------------------1---1------------------1-----------------------------------------------------------------------------------------------------------------1---- * d.32.1 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
[ 120] 222234666776769666555664C67E8ABE55413644455CD77B7DGJG879666883342-12 BBF5FECABBD97487788-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-EFFFGDFHIIFHGEEEEEEBBDCACAAEECDCCDDDCCDDDDBFBFCCBDD64977989768778557A56656BCBDFCE6D87897B577659989GGFJGAE597BCDCECGGDCCFEFF9DEFB566686557GGGFGFFFFFHHEG648898888ADB8B66AACC78EC-------1323----1-----------1-11-----88A978A86969CF D656FAC-QC96B8IAGC8FACA9DAABCCCCCBCDDA7A8A9DABBACCCGGFGK9DBIFF647355345565547355356747768A95GA8AA7A96GBA8B39X9T9JEA9A7556986PI6IAT*G2DED6B74DA7G65A567A53A5A89RGPJ8HH76C59EAFf8BCED*DEECRZUb*AaOKCDHGFG ------------------------------------1-------------------------------------------------------------------------------1---1----------2--------------------------------------1---- * b.81.1 Trimeric LpxA-like enzymes
[ 121] 442553547556565224141313F77BFE94533144232222334254CA7263223423231114 4By28112333---46466-5511C755555786661C9A12453MB1-111519213--3353446689322223223222F21---UTfL5U662--9L69HR4f6R--------1-3222-1-5342123744887A222756FF64745622212223342E457423222225222277456449468DCDCDEEDCDDDDCECACCAADDC788A6B6777878AM666656666666666676666373874232555777652223333356533333332223233323233333333333334563334554666A9444544474AC7889AB97BA2396889NJ8A65655575462-394*6444-----76A782-17473323332333334-265425343E8-7669577GAAFC243817755556B7C33333333433223232222222222--11231111-11112222-286534D9457ABCAA69AAA77D9BBBB68F69789711AB4123239251361576677A5343353411-4565C5246B75AB66448767545A68886EJ6563446545434A977575674311688CDB535P9OBA9BABAABDACC9A9GICDM--2611422-222EA68BE8HJKJHJJKFF-IFGGJIJGKFJHIHHHHHHBAC6888AELEDDFFEFEEGGGCEFFCGEEFD4-ABBABBBBBBBB--23444448777327793328444551542264464434333ABEDFEBEFC6ECCC3B985222222222DHHE888979HEKK874555635433333269CD7777--------3-5222-2-3324322444423253332354537888638I7 2123ADf-9676HECEDFDJIJIUMTODBCCDCFEEGDDCBDDECDDADLPQaVIIGGBCAAA786851786A57773567787896668C8D79B767779AFGH3C*D*q*gwpiTTLNQaVrjQsV**q8ki*RVVRmPTkhNVPQFiQM*Rgacabo*Q*qQVpZZ*Ra*G4OC6V54365RIHPDIHB5bWTZ* 1--------------------1----------------------------------------------------------------------------------------1---------------------------------------------------------------- * c.76.1 Alkaline phosphatase-like
[ 122] -------111111--1--1------4413331-----1-1-1-15229-3323-11----1443---1 8IQ-r545456223XjeJI-Jt22ZuJHJJJTuw**lh**2aAcCI482533CDC215--IFK1NEMRZM6-------21515213213212-52----3M4BCW8E3A---------1----3521113111241335111176NBF9CA42355568634541KKIO941-44322242282511-1-2-35555596B378687644554357C1-2354112232179154443433444534-112-2---11-1--1341-11-111-1253----1223322222222222222211111122214331-1333131333---1--12111844113-2-2--22211322-11---222-2-23E-5VJJF153348AWJR559FAAI93366266565C-8AC77ABFCaK1KKGKKIDJPJPLAFKFBHOD8556H9I88888888AA7456953333433325453534434334334333314s*F59JI8GTSUaVUHFGGFJJVHKKKKCJnOiFRMI23EEG8BF88IJEAaI8AA777CF5211-11123479B4B7163455794432576468815D8BBLO2521212--2-122154544251133345767A4BI4B83AHEECG8EECC9BBIBAFN---5117------555E4472332332232-43334233223243323346A8F8AC24354655546534345922233222-422432222423--2322111999A5475C544635132114--2FFEDC5713379ORQOCGIHEBFDIACEB2121121213643A78668D4688FDEFFFE5664112--3-883344--------1-2----1--2-----111---11----2--1----1-1F-6 4354jP8-Q86289JMQRQUNVLVUUTBCADCEEICDGCHDGGC8BTMUfbdsjKHMNPKKK759777556777775466A666578A8FNDQbPDB998CE9IHF1AlGodkVjfMOIXGNSM*yNuM**vApZyHOKTkEPXOHQLRNbMI*MMOMQGMYGMFJAcHeTToKF8cXI*GKENFjTdoUsZVHOSJJK ----------------------------------------------------------------------1----1-----------------------------------------------------------1--------------------------------------- * d.17.4 NTF2-like
[ 123] 11--------11-----------1--------------------------11-----1---------- 6GG-B213443122354AA-A522D5AAAAA745552443285A332341--212241--5361B26774111111112332622523ABC71B33---5T575pJI1D11111111111111-12-211111A1HGGDF1-1E1RMHMDD866FF9375869F6FKKWA17331216141156455211-33444446543546764-44422568-353-25EGGEEA932111111112111121211-324211232-13322113233212242223111121-----------23223223323321211112223144486668678766354427755531411255LQ444431412232-11144955F-----4DWOSBA6JIKIH7777677775B-NUPPKYIT8A6-989AJE9GOCCF89243G96AC9AF6B2222222253321VAB------------------------------47D6-45524CDD8DA5768799HF9999588BMDIKB24AB7FC8ABEFJEJ565F4387631111111238CAGFSE6C7565CC664-54554325378F8MN3851221111112-3-------54543557825A96466646556445544779478A61--3C49------64223224444444444-4444443444444334434364334424545344334454554233343442-233333333333--14-1-1256661AD5822222223322333322222131116967676898A64667655---------45989888888B8BA44334442211111--GJVVCCEE--------B52---------------------2---44132111111319 8C8ABCJ-*UQ5ROb99A69A9BBBB9997A89999999A9999CA7999C9AD979899998889A875628787838877877676689797888788787FFJ3I*A*******jYdecmi**i*g***3*x*XfgX*YjweXkhZWwbW*hyejqhx*yw*aZ*cd*doxa2gqd*JPILJOQLfAZJJj***** --------------1------------------------------------------------------------------------------------------------------------------------------------1------------------------1-- * b.82.3 cAMP-binding domain-like
[ 124] 22535545455343656244435556844466333453544336376616576744555454344134 5C84B34455531265422-2522662322245A8A4573698674255231344442338834537784552333338767D5465687883756F-159577E47B6-------11222226442436224B4755A9543B985894464677244543674788A635443346343368666A84779BBBBBCBDCBCBDECEECC9BCCC688C8CEBDDDDCBE97777777777777777878D8A7997A888AB889998A9A597888887888887777887677787777888888789A96768888BIBAIFFFEECE8G885EE6AA9FAD457FCGDPNC8DH9AEA68AE975D89643633333549DC3547568833333333335-A8798A9958616557685797674566533576444894444444434553D582111111111MS74A956E63345522223455543434AACCDCA8777688DI888866DAC5B6934655CEDC8D54E86C9K8797E812111116758FT9TNBGGQN9ZVMMM9HFGOFFIGR9A798CFD844344444522322222229455554DBADGBD9J95BEBCDDBBGCC9AECAAHD1-34B8J11-1118ABC77A8888897A77-97878797889A867866AA89BB7A87767888787787778A67767768196667776787711413332368A776P4G64547444333343555565579667CDFEEEIFFEBECBBBDD355436545DAAAIGDFGCAABED5777887755433311H8BA78882331211195634444-1131234111143412222CEBABB9ABB3I46 76239CB-XED9HHD8CDDHEFHQGNFFF9FCEECCBCBCABBDCBFBFRKBHFC6EC6FFD8455855576355474354555551248A8CA8FA8945B9IDC3BMHofsiadcRNVOSWP**M*P***3*e*LSTQjQQkVKSQMKYOItSXXRaKOMQOPHJgIFWATTK4fND*8B99CDGHNBJELQQMJLH ---1-------------------------------11-1------------11-11----------------------------------------------------------1-------------------------------------------------------3---- * a.211.1 HD-domain/PDEase-like
[ 125] ---------------111-----22111112236356333333111251121132424323---2211 --1-1---------16421-1---31211111-1111131-311-1----------12------6-2322---------1--13-1------------------11----------111-------1-1-1-1--11111----1---1--3-------------2212--1-----1----1--11--1---------1----------11-----111-----------1-11111111111121-111----------------------2-----------------------------------------------------------------------1-2------111-1-------------------------1---------11-------------------------------1--1---1---2---------11111111-11--1-1-----111---------------------1------1-1------1---------1111-1-----------1--------1------------------------11-11----1-----2-11-12-111-12-------------1-----------11--------1-----------------------1----1------------------1-------------------------------21----------------------------------------------------------------------------------1--------------------------------22222-----------------------11--11-----------------------------------------------11- DACCYWK4*ToFONWTKOJSRQOSOPOSWLOKMNRRIRLPJNNaOOOONQRQQRGNQPSNLMRPSNMMGPPPQLTPPJNPOQSSORRTPUgTKWavLKMLWcLVeZFV*T****************x*****1******u*z***z********t****ZPk****H*v*ru**TL**T*OLOim**s*o*fLXWRSNt -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------2- * a.22.1 Histone-fold
[ 126] 3242449GJBBFEKD746697435A3374487426235666847646658BEA49C48IHF4435-22 8DA3J567346456UGFCB-CP99KHCCCCCAKKONHIRK5DGG586449A398B58833BBB3C8KFBD723334344275D33433A98A19333--3F584KCD3A111111111222226555476558375664755488HFFGAAH7877565A6A8E8DHLP76846766856576767776465F8888877A57C9899A8AA6D8883A86573233233B933333333333333333434422-22-6323334422225223244322344322222222222222333333333333322333322216ECCEBABBBCDDABBA998BDDCB85683261DGD9669A876775844958945A11111CDJHLF66IHDIL57665565669-HGJEIHJFA8E56BA9BB99IAB98G788AB7A88B58866666666EAA79EHF32222222332233442342334436433286B959BB9FFLMHKINFHHHKKLNLKKLAKOOJLVNO34ONDBKCD9FDCBGDAA9B877B74444444587IHH87F86BAC675AB84HDKEEFEDACAJAOd9F57534666656453334443355778764677BA857688A99674776867669792-2731A11-1117B894B4ACC9AA9AAA-CBAB977B9EC9988A889GEC65867BBCACBCBBCCEBDAB97689995426557555775552226444459899ADD7B666565445532565BBADC9B778I6A9CABE98BCHFCD9BB466566566844557777767677B8CCBCC8774444118D7665662112212132211111---12-3122211212311275677A7AAA4C6C 65896F5-G5D5A8EBDK8MFFKIHFKCBAC77BHBAABBBCB9AAKGDOEDQLHDLLCB8G86435B333543334337743754457CPEDLJH968C8AACAZ32LJoLTIINJHCGEFQDmm9jC**R4aUmGHBCdEGlJDIDEEN*AYNKDMSMPIJLMYBPCTJAJUB7CGB*FBCDJRMTkFYZCCCJCI7 ---1-1-1-----------1-2-11----------211-1----------1---------------------------------------------------------------------------1-----1---------------------------1---2-----1111- * a.25.1 Ferritin-like
[ 127] 222-3445666666642-111--25223113411111111111111-111111-22233322221-11 9EI8L786776996BBA9A-9855CB99999ACCCC9DLL8CA987796664FAEA9955BAD6AAL8C7A3222222-223B97596BBB81A553227DACAF9E98666666666655555547875578A8CEEEC1117BD88A6684388744577966DDHN635333436333366755334B79AAAAAAAA8AA9AAA8CAA9AABB8AA7A76666666B5688888888888888788977-417814-1-773356543232343444644436633333233333666666666446544433344443A74B4444445554367723323311592661A947754B368894434B4DJEDE77788BGUPWJFFHKIIJFFEFFFDCDEH-GFKGFKFCDHE5NLLJIFNJILEFGMCDDFBLAE9AFFHFEFFFFFFBCDA8DEC4444444444224433445444444444468HIA7AIHADIGGEFKFECDCCCFIHHGH8HDIHKOML68IJIFFCIJLHILKJ88M8D8BGG7788878CBCGDJ77C37AA7986558-EEEEECE8GLLIJHA456412222232213111111133464AAGFILJHLGKGBKHGIGIGJMFIGNMONINQ1-98D9B2223339BCF8DAABBCACDE9A-AB9BBBBAABADAAAAAAGGKEDCEDDCDCBDCDCDDBBCBBBDA9B999B84CBAABBAABABA334G77778DDEFDIODE8A9888766665788DDEGDABB9DHHTUVVGRLJRIIFFCKJHA97779979BBCDHCEEEEIGEHIFGDCDCD9AA889865847777431111112141411112-1-22211111231121---22232323234B67 6811BEA-M97188A6997A998A9B99999686778988888A99B99CCDDC7A988877A879886787777AA6AA9678776768D89A9B8997A8ADBE-8QJHCFDIFE89BCADAGHAQ7c*K-NFR9787C8BOE8BB79FB8G9KB9FEMbBN9D9LACLFCFBCEDA*997DEKFPVAQDDGLFCEB ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.84.1 Single hybrid motif
[ 128] 111-11111-1111-11111111---------1221-1------111-111111-11-11111---1- 2221111111111111111-11112311111112221211211111211111211113111112222222211111115211311121111111111-1112111212111111111111111111111111111111111111232324421211122212231133321222111212112121111212222222222222221232332222231222221221122112222222222222212222422132112123322221121122232221111111111111111112211122112112122111222114235444545435213333242221212111122332131123231111113111111111111111111111111111111112-2212211122112111112111211111113111111112222222222221111111111111111111111111111111111111121111111111111111111111111121111111111111111111111111111111111111111111111111121111111121111111111111111111111111111111111111112111211111212121111111111121111111111111111111132222324332422123-22432222222222242233331122223222222222222223222222211322222222222111111111111111111222222111112222111111111111111111111111111112222222221222233333232221122222222212111121111111111111121211111-112111111112111111113211121111111 B9EGbXd-fGD5VVlNPTNNSQQROTQQOKPLQOPPLRLRNPSOOOSTPSORONLOPNOQQPNNOMNLFMOLNMKMPIOOLIKOHKNNPLPIPKGOOKKJBLJWce4k*f**********pt****t*n***L***s*yz*q***k**sm*vt*y****bn*lojwU*lllcemUBUSM*LMRGQ*r**R*TIJQbQRH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.5.2 UBA-like
[ 129] 75-1--ADDDGDDECB-253643HB6661-7C-----------------------------6771-11 4567j5-5222A48n**dd-d*55**dddddu****x***4*F*55663563BBC98B--USk1POeZOfM----111-384D-----11111133---1645764575--------------------------787BB--1D943-3223----------1--12251------------BAB8A--1I756666648677667665666666768FDCC11------6412222221222222221112--1--------11--------------------------------------------------------111316444444444424432221-6-316-13-CA15B9-19---11-3171-ULLa1111193iRe776VHVUMAA9A9AA797B-9AE99K7IECf1OEEJAA9EBEABFQAWCADF9788D9J42444444C11-19C6-----------------------------1QVlT18ZNFVJORYdMJHOOIHHVHRRRRDPlJpl**u46KLFE8LIIXKOOZi27A-2-3761111111212J994rJP--1--1-----765-C-5--88A8HH78----1-------2--------1--1--54-AG7A8HE1676666AH6666B6H8699---221-------42851214334444334-344533342333444444545411672665356655464644632323223--233343323343---6223227777-ME45--------------1OPPNPHQ8CAM2YYXZHVJTMNOMKHECE111111111211142222246245778667F566------22CCA9CC----------1-------------------1-----1--11-1---12-4 1---NNC-943-CCJJIKILFHHLCGOJI9CBCBBBIHGHGHHIJJEB8BEFISAD998A99H6733225227262222228889711-CNBICBA9888GHJTNT-LAIsReHKLMGDHHKPHgRGWIw*R1QReEGHFPEKQJAKHFDOD8QHKJIZQXWFgLLLRGKIRgSd48D7*656BBICITGEC88ZOWRC ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
[ 130] --------------------2-1--------------------------------------------- -2---------------------------------------------1-------------------------------------------1----------------1----------------------------------1-1-1-----------2-----1214-------------1------1----------------------------------------------------------11----1---------------------2-------------------------------------------------------------------------2--------1--------------1---------1--------1-------------------1-----1--------12-----1------------------------13----------------------------------------------1---------------------------------1------1--------------------4--------------1-----1-------2-------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------1-11------------------------------------------------------------------------------- 2222A8O-D56-67D455555654546556445555555555556455555667457444546654442554555451454455657675F7575G9787B6688A-Q*A**********************Q**************************kzrx***o*r**Ug*d4FFK*GIDJNUYev6tJFFiqnne ---1------------------------------1---------------------------------------------------------------------------------------------------111-----------------------------1-------- * b.34.9 Tudor/PWWP/MBT
[ 131] 444322577776777745465AA6F66E498545B67ADBFACHEHEMLBkdA244344636432-45 59K1GIC8IILEEDA6977-7944BK77777898A8EqRc3FAEE8838A74GAA97B44AA5EOGJCISB35553332544H435357879955451136354F4A74322222222322222EGCHEEEDFKHCHHHG43AEANIGHEF7DC55657775GB7ATZLC556555565555BD86654139EHGIFIKGJAJHJJIHLGHHFGJKIAACTD84DCCDCBdYAEDEDEEFEEDDEEEBABEHA2627826423BA3488664575645777867765577777777777555555555555585644355555CIDQCCCCBCDCEC75ih67667A874B44DBeVHD4F449B55584E47D6666645445GJNKO98BkPOPQ9998989897K-KKHHGIGIIH82GIIFLPOPOKLPKL353HIWOINSGB8888888886HD859KT1121111111121111111111111111129776AAHCBCDEEFFDEEGGGEEPPHHHG9DFJQACBE22787DB877GC99DE53F7437B64554454246DFE9YUADDJB9HIIIE4EOHPABEJJDBMFLIFN449726556722233233225946488CBD6D6828858ACAAC69B99898A898A-128BFB211111SAOL9GECFFICJIKCC-EDCBJGIBFEEIFDDCDD9HLJSOEDFDBCCBCCCCDCCCCCAMC9EDDDD7-GGGGIGGDGHGG1142242313142B5KAI8788972354364685777645258W5MNKMDLGKLELFFGHGF5222132127BFEJBBBBBEHEAA6546566434222222E4882223---211218221112-------1---1--1------44632464449652 2311772-424142583655435A9994453354432434245D3E573678BD363754353446353347753445243333317242253656232227479B-2F9D5D65694422242C8163Ij7-76D34527379435424G146557676A7CB6A38343489727A3F24379HACK7DA754B445 -------1----------------------------2-------------1----------------------------------------------------------------1-----------------------------------------------1------1---- * c.92.2 "Helical backbone" metal receptor
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oHG3EFFACBACDCCCCCBEEBEDDCCBCDABBABDCCABBBBBBBA9BBABAAECDCCC4BD9DCCBE3CECCCCDDDEEFGDCDELBBBABEAEEK5HTVOIQBDIECBC9BDBKG6L9R*G2GHPAADAH9CG7BDBAAADDSCG9EGFX*BHDDBIBIlSCFEEHKJ*LJJGIaNpbAQPLJPNFIC ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.11 EF-G C-terminal domain-like
[ 133] 654535GA98A899DB86464778A334835A32543555554686AEA5898366566756883233 3586E2223331-2C98CC-CK229JCCCCC4EIJIDCLM6458A5436332988514-176E69AQGKF7-33311115KF94363822121211---13312324331211112111111122324342444145545343769794554343322335146376684-21----11-1-4525432162B556555463555445548849653598633533333476255535555544555522663-4----4--11323-----1311-1---1----1---------------------11--1--11-----6983533334333344844344354322B4275wo4768186C33252-14757665-11-147G886396D37533343333335-77G8AGAE971-676796789699BA534539575654622222222C4325934----------121-243-3--1--1----1257337CAABGCCDEFBCFFFIIJDHJHJAIBAHGGGE16DFB9B888A68BC7AA67789982111313333AA93CF877BABAA66D1AA9BB6B6699A8687F5AB536566362622333348A676888634566131697AA94BHADDABBFBAKE2--5A5311-111GDC9AD6GHHFGDBFGF-EHGHEEFGFFGFGCGGFFFGJFCC73FGFHEEGIGGGFGJGFGF979BACD619B9BCCBCBCCB11-1434344443647747577562213323345676533433B3AA9988A898B98A8882323132333599F56666AA776763646633322221263442222--------11226----------2-----12-----22323332437512 67354441F535355tediygzY*s**EFIIEJEGEIKLKKEFHIIdNbnv***YXbPSNOPHKX9GFACCCSEVOFBEF8JHNJP8A9MXJeEGKVNUFDAFUIW25ICrhjaYRXHFIGMSGXRFdH**Q2bPfDIFBLINUJEIIJ9QEDdKVNRKHWXFRLJZwNM*HFVG568A*466CGTTbsekNAGODGFK ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.52.2 ADC-like
[ 134] 11----------------------11112221-------1----1--------1--1-----1----- -1---112111--1111----1--11-----111111111-1-1111-111-21211---121-1122111-----------3-----------------1-1----11------------------------------1-----G87966211445565464419A9F6455444444544-----------111---11------1------1----1-------1----------------------1------1---1-----------1----22221--1111111111111111221111122112221112221--------------1------------1--11------------------1--SKLL11111DBUXa89BGDEID7788778888C-HHHGFMKMBNS1JDDEJIKRQKKKFHFHDAEIA5BAEFJ545555556B9467B711-11111--11111111111111111111CJNG5ABB8TIMOONKDDDEDGGSLFFFGAFQGPFKMF27EEGBEHBCJHPBQ94A93333E422222224559944-1-------1---------1---4434BR-1---1---------------------66975A9AH7E88BAAAA8BA9997B89B6AG--24443------BBAC4A7ABB9AAAAAA-BAAAA99A8AB9AAAAAABCEDDD454B8ABACBBBBBBBBBADAA999991-845455555555--1722222555546E7A444626222222114CCDCD7C89AA1JKKJFIHKAFDFFACBB2222222223699B7777798A78DDFDEDD8893222222-441244--------1----------------------------1-------1-1-- 5657RWL-N8A3BCBRVUPOSWPWWTSGHCIEHMONHICHJGIB89PJUmVdlYHGHHFGFGDAB5784D6A7B9CD58B9FFFDAAEESqOVTUMB9B9DEFLSR-E*V*liYfpfYTNTfeW**Q*U**v1xg*QTRPtRSpZQTQOOgRIsVVSeWn*eNmkfQ*npYx*c*CKIM*DHEJPn***K**LLmdUkb ---------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------- * a.45.1 GST C-terminal domain-like
[ 135] 555364777777879858554745755697956876766567556454469774A9889793334-44 B9G4D769DDB35379G55-5A445H555554A788BDF97C69EDB5AB96OHL74D11DCBDEEGFGEA7888989A755D3444378BC5B42---4835675H6621111113332222454654445564FFDGD455CB9676876445444465564376679646556655465FA95678477C9999989D5AA9AA9E7CC8BAA789E9C9A998988BA89A9A99899999978CBD8D7A3BC597687977EGA497A6797BAC9878777899999A999967887778787786CB554BAA8597BECCCEDCEBCD9C337CDC87EA98896375443596398986847748AAAA2322278FAC665B89999989898788F-769568A7BM61IGGEEEIKIIFE67676ABFHBFHF9944444444E9A6B7682222222221--1-----2--1--1---13676436AA88GFFHHEGDBCBFFDFHHHHDHFFH667644ABA96855A9C89B445494677334333344766458965688658896567645554487778867375435455443344444435322266BBE83A33A59777779A9888676977881-483551--111JECCEFCHKLKHIMLHH-JGHIIKKINKJIHHHGHHFLILBDDBDLEGIHHJHHIKILIIKFGGDHHIG52DCCCCCC9BDCD1134666664544549AD967C7A1577588785556537545B698897CCD787888A8D64454544458ABH78888BC9BD98A9A9A99A4444325D55666622222222312--1-3-2-2-2-11111211--11-6B9776B8986B74 4566BCB-M875CDECCIBCEEFIDFGCEBBBBABEAAABCBBABABBCGJDED9ADIFFCC9CA8997CABBBCBC9DB99CAB9DEECGCCBEHCCACDCDGDA17bEPIMGLNC6A85AE9IC6F8b*E1ICS5977ED9C75AAA5EA6N9C89GDIWCJEDCLBGTDOH9CDJG*DEAGGcNUtCcSCFFFCEF ----1------------------1--------------------------------------------------------------------------------------------1---1-------------------------------------------------1---- * c.72.1 Ribokinase-like
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rXXcaKJLHMTMoXIgO**V2cUmAMJKdLOOOGQLIFPHFSOTSOSIMTFJHGAFBIIBDHFKTRZ*YXPMJXep*7aYWZNMIJz ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.26.1 FKBP-like
[ 137] 433121B98ABAAABB-1545224533353531---1------1212223252----1--13113123 76E9M547997563A88DC-DC44ILEDEEEAGDDDEITQ6FCCBD959664CAC74611D9M6EFTHOJ933333334344E54444554417331--57364E5B2444444445554444366443657566BAA9A1116D6A668965755566565556997B64854444644548796532345A99999CBA9ABABCB97876BAAE9A978644444449B3222222222222222222234255644434333344322332332333222222222222222222222222222222222222222221E73A78798A9857274545558326444442BA386525752221333746C788444447ANMPBACFJGHEAA9AAAA999E-GGKEDRGOGMC4JCCGEFRHFFLOFC894GFDCDDECCG88888888D8895BAE3332222233343323333334333333344FG55DDCBCHFFJFJBCCCCDDQPDDDDBDIGYLPOJ59FFEDCGAAJEHAHH8AD96559A6666677887HBB4BB595888B5878279A575568BBABCD49422334444434444444444222499C969A685A657999966C988979779781-5CB9933-333A9669AAFDCDFEEEFE-CFFFEEEFFFCEFFFEFFABBA778979A9988988899A999BA9BAAAB419AAABAAA9ABB3354344458AA997BBD66675646664567577777788C8D9FFHFDHEDCDCEFCFDE8675685464555C777777876688A888855655556596554455333333337631111--1------111---------26554243336654 ----CC6-A55-457PKyjqabNxotkNNIGHFNNMFIIIHHHFEFeUShht**bZbhKONO345455454465554255455584232FZNKRJJ44446BA565-AhFRBBBACF78858C8GU6D9IrC2B7F5954D97E758886N54G8F9CJCLU8GFDBICJC9FHC58C9*776C9SQS*ltt79GEFNB -----------------------------------------------------------------------------------------------------------------------1------------------------------------------------------- * d.145.1 FAD-binding/transporter-associated domain-like
[ 138] 65-1--ABBBDBBCAA-253643H96661-7C---1----1--------------------6771-11 4567f4-6442947p**cc-c*44**cccccs********4xG*55552682BBCB9C--TVi1QLcZOcK--------384D-----11211133---1545774565--------------1-----1--1--787BB---DA53-3224--121---1-2-113461------------ABB8A--1G75777775967877877566666786AFDCC21------6413333332333333221113-11-1-1--1-22--------1-----------111------------------------1--111---211316444444444425332221-6-316-23-C915B9-1A---11-3171-VLLa-11-194kTe787YHXXMAA9A9AA797A-CCGCCLBKECg1QEEMBA9ECEACGQAWDADF9788D9J63666666C11129C611---------------------------1PXnR19XMEXJPSaeMKIOOIHHWJSSSSEQmJtk**t46KLFF8LIIaKNNZi25C-1-3662222222212I894sKP---1-1-----765-C-5--89A8HJ79---11-------1--------2-----54-CG7A8HE1676667AH7776B6H8699--1221-------42842214334444334-344533342333444444546411683665356656464644632324223--322232212333---7222227777-ME45-1------1-12--2QRRPRHR8CAL3baadKYLSNQPOLIGEG1111111112111522222562457798688566------12EEBADD----------1-------------------------1--11-1----1-4 ----FFB-F64-CCGHGKDIDEGHEGMGG9DCCAAAFFFFEFEFFFDE8BCEJSCC9A98A8B44231132141312122244454--1AMBGDB98778DEFLJO-FJDeKZFEJTDCDCEJDTICRDt*J-OKbCGECRCEOH7EECCIC7OEIGEWIQSDUHIKHCJHNaKR3787w655A8ECEPFDB76VLMHE ----------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------- * e.6.1 Acyl-CoA dehydrogenase NM domain-like
[ 139] ------------------------1----1-------------------------------------- --------------1---------------------------------------------------------------------------------------------1--------------------------------------1-------------------------------------------------------------------------------------------------------------------11----------------------------------------------------------1-1------------------------------------------------------------2----------------------------------1-------1122--------------1--------------------------------------------------------1-------------2---------------------------------------------11--------1----1------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------ 5421QY*-D35373C789798787867779889A9778787888786B6788A876978787466756257654557687655555544671876C42443D5GDG1YoU**********************e**************************f**u**ua*x**Tx*W3EDCH56474YYTwCqU27CLGIL -----------------------------------------------------------------------------------------------------------------------------------------------11------------------------------ * a.60.1 SAM/Pointed domain
[ 140] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------I--------------------------B-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-114552---------------------------------------------1-1---------------------------1-1--------------------------------------------------------------------- 1-22hhJ-948-LG*simUcYbbXdbbTSUUUVWZUUZSYRYYQTRTUWfdQ*SNWbWVVVWwFFAEB2CB7D8DAB6BB8FIHEMABB**si***HELISEJ**b1Y********qiYbch*l**V*****6***VdXY*Zp*rVtdkVvdO*c*pu*UaRYxw*EmUgnJ**g5fUWl9B5oB****f**GIGNKMC --------------------------------------------------------------------------------------------------------------------------------------------------------------------------7---- * a.158.1 F-box domain
[ 141] 221---5366666665155331117EA788C8--411111111-5-53E1855--12----422--68 58C989BFGGG7A6A99EE-EF669HEEEEE6JIJKCIQP598AA6A87A83LEG79A22EB91A7DABC9----1-11-14G646682332-2661--196DBC6B9611111111111111332375722552EDDEE111CACBBB77747894444447557DDE7444444444444D88CB---CD8BBCBCC9C5EACDBA559976CDB9D8C9ED433333B9588846966877867477345222112142233113222222-5463335111422244545555662222222222222344222444629523CCCCCAA4A3181117778212532441BB539-1-2---12-22B7AA66521222C7GLS8776868744444444445-66758685F75-9773677767996D787A9DAE9A89B66666666C3365744111111111111223222222222111117657458NM9EJHIIIIFBBB9HHIKDEEC7BJMYLGFK7DHHAC9AA9PEODLEAD9F6765622222225434BG9AL6J7GD38D8882D9DB8IG748788997D7232-2233241111111115999B78B9A9799688A8ACCA7CCBBB9CBBA9GB3-16D8E221222A897EB9BCDCBCACCB-DCBCCCCCCCDCCBBBBBCGHH7786698999999999999998CB9677C5288888888888722276566666559AF7B47755B6424435449888878574KFFEAEAHAHHAHA9GIEE666456546D789D99999CB7777777877778433443D7DD5455111111114-411111--12--------1--1-----1-1------9729 32-2CDG-aGC6CDEAAC9CDCCCEBAAAA869AA99858678AAC99CCDDIK98B7ABBBB9ABBA77BDBBABD9BFA98988A89CCBABA989896CBDIH2AVIdRTRROVKKKJNRJaaGqN**c3kT*EIJHXILVLJNLFDaDFaJQJOUGMGFokL7BACBLRQA9PKT*MMKRKYOVVBSLOLQLKKH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.46.1 Rhodanese/Cell cycle control phosphatase
[ 142] -------1------------------------------------2---------1---------1--- 6AE2F46455556578877-6955687877769CDCCFKI79CCB66573376A6338337862D9BOOH554554651163757A6697891A573--9B877DB739--------------23344425455334444---73A78654733556769766743AACB161-22251-1244323222B49ABABCFBCBDCBEIA98A99CB9H665A655AAABBBB89A899988A9BBAB898799C4545647546999954756966C8B77687A7677555666566567987876778776867AA864585858A77777979964C76544367343A444355885529544457433671FBBB9CC9FFGLHLGEIHIFDGIIFHHGHFFGN-LIMJNiNMQPE5HHGMJMJMJMPMFJ878IJMHJGFEKHAAAAAAAA9EDCBBBC11--------115466356433534----5CDCC8DEBCKMJKPKNRCCDBOOLOEEEFAGJUMHKKK58KJIDDJJEMHDGE9CCI9B9DJF79788669AAIFGGCD8A6897C6CHD698CB8988DBBBBJBBE667483343555654556455644798NRCBBCCBDAADIJIHHFFHFFJBKFGEDD1-88C9B-2-222FJCFHIEERQGEIDNFG1UFGJGNOHJJSKKEEFFFHFGEFDEEGMNFHLKHKHHKNMKHJLEHDFEGEP3IHHIHHIGGMEE32BA77676AAAAEDF988788B8697669679FFIGHIBA9CCFIIKJFFEMEGGEFBOLH644344434AGJIFBDADDJEABCKINGJFIGEHIDDC52B999888822222222531-------------------------41344444441163 --1-674-411112343214431435222224433411121115552156-26322512221-----4-1112---3-121-----1112733A4B1213-I124321J9KA6C57CA9AA8B7IC7E5RaC1AAB586BCA8M8A8957CB8HB73C858639795OEE58C61--23122153LHVm2GV2JE3341 -113-2-1-1---2---111-2---1111211111332131122211-1--11---11-11-21112-1--1----11--11111---211--1--11---1-1-11111-111-----1-11---1-11-11----1-111-1111-1-111-11111--1213--11--1--1 * d.2.1 Lysozyme-like
[ 143] 23223233322222432233333333333333333556555553334333434333333334633322 5574566666675755567-85445566666555556766566644655554555555335557747666555556556565474866777747-64225789699B5B-5655555-545558444444444445555755564779788A67888898879777877648544447455477766773977-AAAABAA9AAABBA667778ABA77797777777779A87777777777777777777-7878877777887788988776888888888887788888888888888888888888889B88888889AA8A9999999A9A9988AABBAA97779A7587595575877779479768999955555676666666666666666666666299878777676466656667666666AC6886777777866666666666669864444444455335555555556555323436767566678A8898A8888888898888788C9888878787A8CACCCAAA8BB99988CB89A99996768BAD698C8C77787775A89799A89EEEDID7897777777777676666666A778988DDBBCCG9EFCFIIIIJKKFFFHI1KJHKK4176778555555BAAAACCBBBBBBBBBB-BBBBBBBBBBBBBBBBBBBDCDAAAACBBBBBBBBBBBBBBBBDBBBABBB73CAAABAAAABBB446A5555587779AB9CCCCABB9BBAA9A9BBBBABAAABABDBBBBBBCBB2BBBBDFB555555555CFEEEDDDDDDDFDDEEDEDEECDC6666558888677655565555B6744445-545444344445434544477577656665976 JI89EFB1xNQBAAD77BA9777796798999A98887777779989BB89C798A77899989BAA979EDAB9DD99CAAA99A99A8G7779988964C8B8E59*MRCKCEHIDCB8FC9OLBHDZ*G1FFG9BB9GCCDD9DBBAD9AECBHDG6FFEIBJ7J98M79A8EPOV*RPQJGLKKW8NMXePILNM ---------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------- * d.265.1 Pseudouridine synthase
[ 144] 655445445444444655566562IEGDHHKF2223322223822322223525455655546633AG 1-1-1----------------------------------1-1---1--1-1--1-2-------12--2---1----11----1-----------------1-----1----------------------------1-1------1-2--------1---1---------1---1---------------1-1222222322-2222221-2211222-111----------1----------------------------------------1---1----------------------------------------------11----------------1--------11--122-3-1-1-1----1----1-----------1--1-------------------1------21-1--------1---------------------------1----11--------------------------------1-------1----------------------1---------------------1--1----------------1--1-1---1----------2-------------------------1--------1-------1--1---------------------------------------------------------------------------------1-1--------1-------------------------------22-11-----------------------1------------------------------------------1---------------------------------------------------------------------------2-112---- BCHJYZQ5mIHIZdgOPQSQONPPUPSMOJPOONPMJONPLNPMNOIPNQRNVTPRROPPOPQRRPTRCKZYQMNZaQZaWOOPPQNPQUqWPdacSNQOMRPlwmEZuX********mw*z****u*q***2***q****v***q**t**wy*w****hsjpoltZ*hj*TwmdKbZO*MPLOX****S*jh*ZiWZO --------------------------------------------------------------------------------------------------------------------------------------------------------------------------5211- * a.74.1 Cyclin-like
[ 145] 11211232443542372------1HDC855F84213223D69524114-5D32-11214213251-38 78W3A486654355ACC44-4G22D7656766dAJEGETX2FOS3423533EC3D27232DIQ2F6GHGA63444FIE5468521321aPwZ2cB53--4M3F985DA552553322442222E232455442833334326AB5SGFH3611146H3J94456-3EEQ12421231B3144DB633234653BFFFIFGG9EMH8CD4797367BEB7DP464B23366639CF7A55976BBC7659C75E7766A58657AB98775C55429BEB88746345674588E9798C579B97AA766566DC664A7967D67DB767A99BF8BFEC43438482427JC6F7OGIB2B54353933464KR4584C42H69JATNGC792898887888589N-RILKHPHDIf94967P94VQ68EG7N666NAFEGEA8CCJJJJJJJJL79A5S372222222222Hh223322232222222222EFCC36935QCDHGDCR6666QOUeECBBCIEaO8Bhc29PKJHFBM8JKRBE9B9BF5495C56234235CBgAG5CT9768BCkBAB56A2BH7667J86867A7B5C525151162322321222A3446ED5FBFX5B7BAH5LPYOAFHOBGI7JAAI8B--59956------GBGC9IABVXMCLIQHB1VB9IHKPBJHWGGCB8CAAGRDRHSUBFF59AE6CFACHCE9GFEC6JLJ9E-GBA98DC9BF9G--5356646997C55848633482374556A86967BDD36CCC54DQB6D7GALLEGLUQD322225222DD96HAC7MBID7CED5QBPCHAABDBBA--435534442863--1-623-----121-13-------2-1-33221122121112M96 2332K33-R13132323223433636333122223224333332213323333233322222223422224222313-22222222122843354J222639234K-46E68979BE2222276873747l6-9554432332G73344244184644D35845P62624I44E323K2g44432633K34C439c358 11-------11-1--1111-1-2---1--111111-----1-1111----1111--1-2-1----------------1----1111111--1111-1111111--211111111--111-1-1--221--1-1--1111111-111-1--1-1-1111----1--11---1-11- * d.163.1 DNA breaking-rejoining enzymes
[ 146] 22211-23444444353312211-61163241-1----11-----1--11632--2-453-5221-11 NQQ3h566A9924157988-8811AA88887A5AAA99GE7A79CJG5BFF4CEB427--ABB8Q6CeZN7C9994DA2-1-842433MNXP3J443--9O5DETAMGE222222221111114676979888B9JNMED222L4NGI8CC465333466635529AADA243311242331GCC56CB36D9EEDDECDB9FEDCEDCGBB6DCECA9A66MIBCCBC78b73334332443334421153696168-2A3C99225823357377544465453444445454455532222333422224442214443D55EI6666666B68I7443EFDF3D8266E65AA5653E866ACCI415545JBB62222227AA8555AA7AA22222222224-88F77A898882A88BCC8ECCAB45B86753CBBB562222222227333559B222121211111222221132311331333543444645678856795777556A767754664774222556715111417A43383638622322222149874754626555A455755B646763D9989EH46342555555444575554465524222DCCB4E83F6B38657692766386394382-17315221111BH766B7ABBCBBABBA-9AABCACBCB9AA9BAAA8CFDA9574BB799AAAAB7ABA9AA8969AA9318BBBBBBB9CBA223311111455431C4C34367612213333344464532229M55654778A8887B676112112111569AF676769BCDA77JHIHIEEF44443255CC88BB33323223736----2--12-1--11132--2----5AA75B4BDC4U7B --24CBU-2132458QLKMPTUTUVTXA877684454766655877MMLPJONVPRKKHDEE44A36735429298A4F95765587AAGMJL9K9C9C94JC878-GTHwKWKSRMDGBGGMIYZEUDz*X1UNdCDECL9FRIEFDCAT9AWCIKKFMZ*DWQPETLZKIMFD6EFH*ACAIFaXpaPMW33HIFMC -----1-----------------------------------------------------------------------1----1-----------------1---11--1----1--------1---1-------111-------------------------------------- * b.71.1 Glycosyl hydrolase domain
[ 147] 1155-2AABBBCABB9-797677594553364442655555453356467C6B358576-55443-8A 9BD6E55644585573355-5955AG656667A7889CGD486D765559644784444466A698GC8B775556884695956A57ABC937554--8B89BB6C8A433333332222224867778876AA79979213ABB8A777756777876679878A8AD778666677666867985658987786879969C99BA9B99888788877DC7577778FD6666766666666668558795646956454AA558687757455544444435445555657555555555555555555574445556595575558665454A97756758662245665CC589557455666236865B99B66766A9JAA87777767AAAB9B9A9AB-88B89BA8AE86ECDCHIFCCFDECC9C9998DADDCB788888888A88788A84533355533111111111111111444459BB669CA99CDDCEDDCAAAEEBJCCCCBBFBFBEBA78BCCBCCEABED9CA88ABA89B86666666767BEA67A8688958855756B77B799ACCEEEE79765746555565555555557754577BAA9CBABJB9DCBCB9CABBBC9A99B896158B8A331222CCC9DB9GGHFGFGGGH-GFGGGFEGFHGFHFHGHHDEEDDD998FDDCEFDEFGEEFECEDEFGFFDFA7AAAAAAAAAAAA336977778AAA98BDBE777766555455558779888B889A9EGGE9EDEEEBFC9DCB877676677BB99B99999899DCBBCBBBCDDD6777669577BBAA22222121531------1---1-----11-------36434566357965 1111567-A63-657ADA6JFDBHMGHAC9ABB9876977666975D8BFEKUK69C7AAB9A9A585594677B874776A9B78894EM9D888A8848A94A9-8I3EBDCDBD8D77EBAIG5U7h*M1PCO9994DAAJ5AA987KA8D9D99CCMRBD989E87DHAA478A9z67577K7FI4VF48B5556 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1- * c.30.1 PreATP-grasp domain
[ 148] ----1-321---21-1-1222--562133925KG421-4132-5X15CD8*ve----322----7--1 BNh-c--1---1--1--44-4-115-41433-1222-11-5417-91225617812--1-3124H15EF842111121---143141-75US-51----4gE56dZJ1e1322223122233414-A11-2112-26666---82O86366211---1-12-15D7NRIF-11--111---1512--26-52844444633-26543674CC78422412633211-1413K111444334311133422414-2-21--1-44311-211-12-1--1121---11-11122211212-------------122---2222B1-B3-----1-1-48333----G18111E11-643-11-3--11-514231E92231H62845686B23642BA11111122112-65899463533-4653BF2CBH522382441412136-32222222225215682---11111--7721--12-2----------4424194555F34758E4332667B78A5449C91445-363L714113611854E5253251-3732-3--2234KB584-3-14131--3E4576K324D94DV45244233136121-2111-2452-325212344S213143-13331433413436238---11-3------25DJ3663436354434-4334334224333233435452GMAE66625635256232343722-32211-677667847878--12-----31--1-C353122-24314-1-422332353111EIAADA4B59237351BF8---------11-1322222-1213548F7FD568886A--93553366---111--5-3--2----1-1-11---1-2-2----33221313311L4D eM7BPRW-bFF77DIMFRdcgmOpeqX999CEEB658798767A99hgKcnm*v**NZMLNM36475513557345565887567D48BLdNFGQUA8964UA8JZ2K*u*acWWWZOQHMPVQutOuI**d5qb*POKMnOTgPISSJIlMM*WLMOaQejYXwCKVMNVKYtL1JF6VAB8XA****S**H8****X -----------1-----------3-----------------1-----------1--1--11--1-------1----1-1-----------------------------------------------2---------------------1----1--------11------31-2- * b.80.1 Pectin lyase-like
[ 149] AABJIJG9BBBBBDFBCDIIILIM86694966ECIPNJKMJHLINKLJRPVWQOEIDGEEI5A8M4DD BJM7I687555344756BB-B73379ABAAA89777C8CA9JKJ52246221335323--HEG5D4DBAG8111112369GL5CFEBEIHBD6D562--47777CA84A444444454555551FCAFFK9CDHI7AAAC978B6GDJHGEC6577856664ADABIGED54546576545676777KF5574779797885879778A866588877898335333333CC733333333333333443333--11211---11--1111----42433333142332222222111222222222222222235553332PLFOKNNNKPLKCOEKIOOCCECCGRE9E9IFITUTMULEMQKIIJOCA6AMA755C13123BACAD597GHDDB55455555554-9BFCDFBB4C627446BA8735798A78674BB9BA74799999999GAA8AI7F1111111111-111221121-11111-2-15575644436ABBABBE9997A9AA99897AB9BDAE9258988746769698488A9666A95565555555E9H7YWbLLSJHdYRRNBZbZYSQiecDCJEFDQiBBDHBBAAB9A889899999GECDDDC79B785C6548BAABB8AHDECCBDGHBFI3-36789331222D7A69969AAA9AAA99-A999AAC9A9AAA999999ACB9DH9AACAAABBAAAA9B8AA69879999449AA8AAAB9AAA--37444445444F7C487776665556376686664647655E5AAAAAAAIADABAF87732222322257CDE777778DADD7766565656333333IJ99888811111111832---1-------1------2---111EJNCGIHJKJCA94 21-1322-211244735642444433222223274642222332222557446535133423211112-121122311312112-1221244523311114935631688B574344355445566394Ov9-96D423463654444525448245371-338572311549948A96r979A7A79C48668A3689 -------------------2------------------2-----------------------------------------------------------------------------------------------------------------------------1---------- * c.1.28 Radical SAM enzymes
[ 150] --8111236213FIP7-31-1114-11---2--1133111--12233311L32-131-213-121111 6EE9VECCA9B979EEDFF-FJ66BJUIVVS9JJPLWdYg9LPTNICJACC8GHF7BB44QUI6dGahgd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d*K2RHZ6689F8CEA7D746C96JDFABD4556D6A5J55G44962123811253935I4322194862 ---1----------------1-1-----2-----------1----------------11--------------------------------1-11-1----11-----------------------------------1---1112-----1------------------3---- * a.6.1 Putative DNA-binding domain
[ 151] --3323121111111121-11--721121332DFA666AA86APRGIG74WJJ516111261--1-24 2432K56555533585566-68228A5655678787CDGC-ABB74555423787336--566-95DBCA7155533385FC21122189A717442--6C135E9914--------------2565686338572222577471B88576855553464434638B9E54444444446464241143624FEEGDGDGG6DGEEDE9AGEEFDDG626FB898777759K366757767766676655878B83AC3A646HICC885A995666766674447AA666555575655544454456444A6566455573EAPcIIFKLJLFK88NMM5AC9G7A522DC52CBB4-6668413164DA154A779122116668A5598737522332332338-9DBBEF98AD5-G994CC8FJCBE9964449C66762944444444454421325--------------22-21---22-----2425948986BEJJIIEA7999HHCA989947MFGBGGE12CBA37B76DAB9I79D539275534544443526CB7IF8B7788BB7883988B99ADC132348AA4398332223224222222214-1-55B9CB8A9ADB9BB999CAEBBCAC9DCAGA2-35533211222FGDI8IEGEGFGGGGGF-FGGGGGGGGGFHHGGGGGFJLKHIDBBFFEDEFEFEEDDEDDEMFEEFGFD83EDCDDDDCDDDC223512111223236CAA66698D355555555EDDEE68547EBFFHFDGFBFEEFC998A32212433249AAF88888FCCBCGFEBB9998A6545--1G551121---1--1-91311-13-122314233312632211123441271115841 3323448-RA7748ABCBCBEDCHIGI778887B888BA9989757B8DECIJJ97BA8899AA85584A97B59A9598BA9A9C579GE9C9A767684C6JGG16dEQJQDCHGBCD8FEBbRAQA**J1WGd7EB8LEEDD9FDD4GC8Z8FADFAOc6D6A6H88F77B83DC7*A99ADGEGR8CCDCUMMJD -------1----------------------------------------------------------------------------------------1---------------------1-------11----------------------------------------------- * c.23.5 Flavoproteins
[ 152] 221---2-2222221222111111322121-1--1-------1-1---------11--1-12112--1 3482D346446353E7778-9C55EG77777ADABABCNO263674533632DEB76A--9BD4ABNFAA4----1111-43611--121---111---24313857412222222222232321111--1122154464---67326433356444332344627556322322324212273534---64266666777366676632432376722463642222227523333333333333343333211-11-----12--11132---1292223-1-2--1221211212232223333233322541113442-32-3111-1112111222----2----21---53-1411-21----31-216BAA622212A5MKN78BEBBEBBDCGCBEBCDF18AG57IBFAU91RKLGJJUOMPSNHD565ABN7677JET66666666A9A5227411--1------------------------25DG715EA5ANIKPMLHDDDBJJMPFFFF8GbNREGEC23EAAC8B77A9FAGK544-1238254343442-27B455441332231222-11122231222226A-11--11------11-------1-1-22363167383A734544454743336477395--12332------73444377777777766-7778776778777776776686442357664666665546446856777862-3545555355551--33434344451877A222-22212213113B9A994856384DEFEFFDD5CG8AA677211111111-122533233564565557B773442111-14-33432222222212----------111-11----1-1----------111-114-- 4456JB6-C752569aUrWzVec***oLNGMHMHJGEHIGGFHJKIfYQVfy**hfhbLOKOA786895965A8965365A9998A577m*iUokMBCB7FPKE9C3BhL*XQKNHNRRNPMPU*fKhF**h3gUoJSJKWPMcTHSNPOTMJUTOJJRPcaMbFbscgc*GGTL8IJF*BDDEEOUXrfTcGDQSGNL ---------------------------------------1----------------------------------------------------------------------------------------------------------------------------------1---- * d.16.1 FAD-linked reductases, C-terminal domain
[ 153] --211-1-1111111-1------133344633111211111111442233335157457841223155 3634F637AAB455GCC9A-9F22EJ99999CGHGHLOcW895C66584552E8976622D974DBBDCG51333311223434444367554555---654586475344444444444444566667566756344-344533545655333333333333334445433333333333322522222248555555554555555666677555355674511111144444444444444444544562-2----3---3122--112221333333----21144444444443-------------211111111-4626B7778778A7A4655688747461145554486566456774324344955533333378DAF436B78D8445545535553CBC9BGCG5634C885548887ABFC33367C644557B77777777855455543333333333--11221122111114333243A547FBAFFBCGDGB9AAACCFJAAAA4CMCLGLKK46CAAB9586H9C7HH5C87958946787777554BF74655765865766636564457565575AB55222222222222222222222223299DCC7B8A7DBCCCCCB8CCCCCBBABCBDF4-36748431444998B68AA998A898AA-9AABA88A9A98A99A99ADDDABAB9A9AA9AA9AA9AAAA9B9998889739AAAAAAAAAAA444644343677789ABF444645333333333DFEEFAB578F7GGGHGGEEEKMJJDABA5333333334AEDDAAAAACDDEEABBBBBB77755554364664444--------211------------------1------65344424446434 53239AC-XFI498JOPPKOUWPXbURGGGCCDGHFFGFFDHFGHIMLLXYZgiPXRJILJNJGDDDE7DBECDDHK9GLALLJCPBFCNSDPDHDFBCC9ACNFJ29fHSHNCJKKIFFBIMGcTDREv*O1QKZBCDALGILBBGHC5JG8hIIFFH7JN7BED8EACJ98BBDEDD*EECDGNNceQPKJHUXMNK ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.43.4 Riboflavin synthase domain-like
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pDHFIAIEE977A899FG7I7P*B1HEO6895H79C74AA87D79G8GB678DG7C4A8898E96CBEKLJ*IGDEENEGO9FLGMIQCBJ -----------------------------------------1-----------------------------------------------11--1-------------------------------------------------------1--------------------3---- * c.116.1 alpha/beta knot
[ 155] 996B7B777777887778BBA97A544533446678B989AB99857858686AGGFEEFF5555456 8773842222232346644-45225444444466554434344723324442335223217553356576421111224-2247576655532344111442356734511111111111111324323322452ECDCD213B5757B786676677787688799997755566655556879AA55356767888888798898799889A7986675753566664C55666666666666668777A724-55212348822663433246452343545455333333333332333223322223455223444447378444544575952555566436136783643664374656564335765655855656856884556455677677777777-67677976675487767865578767585997778778866666666555448783253333322332332222223222323464775437543766777B7888888977777787A676744766868558777866857565544433333675597B9A9A7878958775A998988B898B9BB593332244332323333332446553AA977897778679AAB99A799999A779672-4697833233378547756787688998-87688898789887767789B8554558677787777778677977666665287777776777722566566556567997A55545446656545553564446869799ABB9AB8999989AB3333342337779B7777799AA97777876778878735715544663334344455211214--13--12---33312144458345545562733 A855CF82Q89499EEDE9ABBCB9BBEDBFDFCCDDEDEDEFBBBDAACBFHHDCBDEBAA988676468678886586676876A98DKADDHK89899FBGCJ3BmFVfmXbfeLNLMORSrdOlP**d2kYxPNQLbOUcOIRRLKaKGlNcWRTGZQIHKPDQEEe9BMFENNM*HHFNKdhs*AzVJHHGEBM ----------------------1------1----------------------------1---------------------------------1--------1-----1---------11-----------------------------------------------1-------- * b.122.1 PUA domain-like
[ 156] -------------------------------------------1---1--211--------------- 8592c684334A26dUSII-IG77*QJHIIGGJFEGyo**1cWS2113151145732711cU23*LniS*8-------11341121125313111111-2I222*35141111111111111121111411112112222211*1EGI5NNR1111222211211CZM*41111111311121111111221p66858D5DA6A8EJ612CCJR66M331B311222222y3-4444444444444424432323333332324A333332333322244433633AA22222222222333333333333333333333331227B4444C44445j3FF21113-7211541154611411111111232519422222222BAC6W2226I34333333333324-8898B87667117DDP555645P87F451427434424522222222263244251111111111111111111121111111112232133324CEFFFWhWdhU88CC****L*CDCA3A41255O12A31C345G62162112D1112111133C34915745125832222-A8A953C2C3333**432331112111111211112121112337A1-2C4223788788N88788797797971-12442-1-111O2U7335366L3JJ744-645444949869B333445227N9s*7333343334333433373445434119A8AAA5765A5112457466434456Z2I11114111111133176AB717111KFPRKQocVa8EEGC2dR*5111111111233H2333373866447343322222221122221111111111111111111--1---1-----1-111-11122122222222G13 2111hg5-622-44RcVnR*r******EFEIHGz*nVTTUMSSDEEgR**umolYXs*jJGI333222133232322122233333476FIBV9E7333244I665-3P9K7767623563584753E3J*7-78C23527255334411632A365473253G54365CH8E492BI6kB76FHBCAIy8C545955H -----------------11------------------------------------------------------------------------------------------------------------------------------------------------------------ * a.28.1 ACP-like
[ 157] 22-13-41-------11---1125311-42421-2---41443--5-2-453816766664-833--3 498262322221-2724----3--25-----334443643231-1114-2217542-2--1-61126875-131133354BA512---8887-8-24--37465667-21------1-111113212122112716873456366B77322311222333453613A8A8142122-42222-1244224689RRTRTSTVJSQUUVX58GG7JVQV669J565666665TF333222343333333632342552332321266445448411-3222221---11-33333333333--------------112231111-A775888748763443DD58785B21463464CC4C-2496534514B76-6444811-1232IFF42CCFED99ACB9AB9BAG-767569657P4-PNN9JNLTVSPM88463EFCFDHGKLP777777772-1628CD----------2211221111211112-3-C34945DHFAGFKKKNIAADDCPOHEEGEFAFWED8DCF14BDD88A99C8HGFA6B9273BFC355544311277A57J1CD8889JGGC1949569332655755274464222223113-----1-2341111HF49D38877B7CCBA4698874575748A---25121-----77B98C778887A8877-867986668887677777BDGGCDC9BA7AAAECBDACBABAID65787874-GBCBDBBBBDDD113B12122466633JBK64737A163523-15KHHENBB38625GHDE9KHLA7967A3B73322132235ADDE9CBBCSDHEGDDA86873331111--37553433--------51-----------1--------------6515223212-742 A2CDHBG-OB46FGLCCGCDB99EAFABAAEEDAE9GCBCCAB9AA7FDGGFLKCGGDBHHGA663753B437875728959875779AFLGCKIHG9GFFDHRON2F*H*PWLHUIGDGBHOGWUGVBp*R-SJa7BCAJEFNHDHDBAJ8AREOJIJSUECFHD2PBDBIQLRJJLC*BHGEIXmv*E*cQNccYYR ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.39.1 Multidrug resistance efflux transporter EmrE
[ 158] 11---1------------2-1--12------2------------------5-1---------11-1-- IM*2322222222222233-322222323332222222232222222222222222232222422232222------------ABOHL4461-7---443HGBIeP*6J--------------2GBBBB989E7A966C9---66G6E565355994447544548888514222125-2216C9FF-1--444444444454544554466444455655444------834---------------11-----1--1------11-1----1-----------------------------------------------------------------------1----71-3-22-11---2--------J3*MDEI12112IUyvhVIKMFOONAAAAAAA9AAG2NfVIVbRbJL8-GDDBMHLQJIVWPX9D8jBPPRQNVIjMMMMMMMMJJKG8UC92222223222222233222222222222236PXA7GQOIYjqqqsiRNQQLrpigdgfbQexiqcqg*GYhbbqbLUTaeWXdJYOThGQILHCC977A7SWXZetK132-4664236653KJQBJKJ6-FJJIbw-3VDHHBJFIJBE99799A999QK6WhCDEC-CQSWAJJHFLKMLHLJIIIGJMOZGLT---ZKBb------32--3-222222222-2-222222222222322222-222-----2222222222222222L23-2222--544444344444---G-----AAAAXEc-7222332-----2--3-------KKGKPmmnmZehdPcabUa988---------GCDDRCCCCCNRLFGDB99FA9CCB1111DCX-LLFHGG--------1-------------------------------------GN79 64--222-B42-2223242322322234424442322222233222433222424222333322123322232234333322224222225322432232222335-2H294654711145-13692B48Z2-7831335533743324242461413821624343535A33534623k34344B67N35557A3446 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.3.1 Cytochrome c
[ 159] 33314423666656732A56526-E66G4IG455133-3-11335-1311855-11111126443-33 6DR4Z3267883613B933-34223F32232258785CBB8H9RNJG45IG3HKK54D1199B5O4QOSJ67577686-146621221A953-5-----17274N2836--------------1121111--12212285111D1978B5673533343433454AE8N83432345332249D421741A5899999A68568888875556886825647777888869O266666666666666744494BG37835545BB99AA3695CB566333211114422222222222111-11111111122211122253514944455352436211----A-32-3332233312134223315213446D665---1-C9BC91236744411111111119-78B7AF7BCM2-QKKCKKLVRKGKA85726684345854444444447A963435---------------------------1-14673638869EDECEFB5454BAHF555636GAM5867--5457352353689224213112--------1--1331241-2---35--1-5242326418CBABQ-31-3--------341-1--1132-22243394441-8242232424142232112223--21123------876A3B89BBC9CCCAA-A89ACB9AC9BCF98999AEFE871247598A89A9998889AA78987884-A87888778888--1--1-1-1232136961-18-6-------2-4434436132F3886859AA7988A7978211-12--1212242222222322659ABAB7794222--28332345111-1-----4----1-----11----1-5------22722656663B91 251298B-F66346DVNSRbTWPhdheGFIEEFIECHIGIIJKDCCdUToYfvhaXNMIHJHHAF5AICDCHL7IBGALGEHHGCCA9Dt*jNMzPKLOPGIGRNM18*Q*XXKPIUGDCJVIOkbDoG**P1cMcDGIFKBBcX9BCC8TDFTEJJDNFICBLOFRKHNcUNG84IKI*ABAJOWamlLSeKTlPVUw -----1--------------------------------------------------------------------------------------------------------------1---1------------------------------------------------------ * c.1.7 NAD(P)-linked oxidoreductase
[ 160] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------------------1-------------------------------------------------------------1------------------------11-------------------------------------------1-----------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11-1--------------------------------------------------------------------------------------------------------------------------------------------------- GB89eZc-*fU-WZmaghabdddhgihYYYZZZbbYbaXYXYaXaZaabdggpiZcfaYcbacUbSUXPYVWXZaaZTZZYYWYXYQOOZ*agcbfYbabcadzry-f*r*******jbujipo**f*f***2*u*Yohf*hn*gYonidqXS*mqnopXlhWiaYZ*bi*chrXVidh*hecYf*x**e*z*vppmky --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * f.42.1 Mitochondrial carrier
[ 161] 11----7867766466-311112183455445------------1-2-1-312----1-2-322--35 29N5X229ABB311ifXLL-Lo88hYLKLLLQpxy*dT**2LEYBL993551LIP45B--LBM1HFSNMF3-111--1----6-----112312323--2F3B8MLH4M--------1------8737576852888866111A4H6999A43666436443554CDBM722222222222264611---1-2555554653555435243322555-2-7733111111EG-22222222222221222351-2-33---1-22--23--1---111----112111-----------1111112111111111---111--114311111-1--111111--------4--1-13---1--------1--F-6P78D121126CRDG434655A533333333338-88CA7H9BEMF1F866FEGKIHHK487865PE755685B55555555744373431111111111111111112121111111123R*81AJDACJHILMLDFHHCJJJMIHJJ5FSFbDNID24CAE9G54397F6LF5C8575A4311111113285BAD64B12-4-3-11--42311241187D9GM-6----------------------1--44642674617433322232122213122123--16443------32432334552423234-44444234435274444447663326222222222222222224424333411132334533333111522222333366758111-111----1111DCCAC4A-2-52AADB8E9C48C983675211111111112231111154355669676643523431112FFBBFF--------2-2--------1----------------2--213132236-8 6*7AHH8-PCB579LACE99DH9E9CC5556564646655855533B689CHLL57D955688492542622536332226453565457K9C89B8777ABBGHB2Mp**fucfmdMPNOPOQoePoM**Z6hVuJQMLXMRZSGQNOIRHKiSUTTZCGQFLFMFQGKRBJM9AIIEqDCBJV*z**9**IMz***K ------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------1- * d.129.3 Bet v1-like
[ 162] ------1111111111-12---121--1-11-112---111112-111-2331----1111111---- -221932533352232222-25--242222215434465425667774575556433555769254A9CE54333333222-1---11CB982C45---383776496D-------1-------32143312154-1113111416445463332211111132143441111111111111435----11-15555554636575542-11-1575---3323222221321111--11111111-211--4411221221211222211111122222224343223333443333333223333333323432223332-2112332333333322--133331111--2--1122-111----1-1256-C755743333343433224437455455554446-6755654378347776CD7CAB8742354663646665455555555344533461121111111353222233222332111114374344444777677455557767666645665756633664455555454734445634532222222334573845531221121112423--2-424464GC33322422222121211111112-123337825568586664444564454454464571-26334------44552323333333433-33333333333333333333333323335343433333434434233333321222222222222113222222333333A43111232211113112443343344442778756765666565552222222222666933333996779999999556333311211144661111111132-------12-111-111---12-222---11------737 9C56sDP-ZDF389HBCHGHEEBHELDBBBBAB99AAABABBAA7C9XDDGHLEDCGzDFDFIAD9984EABC9BDA6AB8DCJDD787GMJCDEFAAA9ALFHz*4L*q**sgl*UNKMGOOO**N*P**d5dZlKLNNXPO*RGROLG*KH*QVRY*KeQ*****RCBIFJ*JBS*G*HGFHFjjb*5qfBMWWXcI --------------------------------------------------------------------------------------------------------------------------------------------------------------------------4---- * d.151.1 DNase I-like
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cBRJMIMHQGDE99HFHJERE**M5PKSEDDELBGMD7EC99F9CQFJCCIGRgCKGHBKCIVGIFCCADD*CFDCBFIMPAIIFDKDFHC --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3---- * a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
[ 164] 777385657777776669545565B78A7A985332223222476356556644795355C8567-57 A8D5C566665556B77AA-A955AAA9AAA8AAAADBCD6E977664556599996722DAC5G9JGEF744444442334955554555727--2334A58777778-12-111-32----15565565685688899444B8B6C866965575555576967BDF8555566566566A5444554477BBBBB99B7BAA9ABA67787AA9AAA7843444444C94779798888887875555744-3443533-443334142143545222222255544444444444111111111111153455533326D8577776877776679943337873548785996C6669766555374B678779-22-265F9D566AA99D46554554459176A66B8C8H61A7779DF9BBAF8B8889B66877B8E5555555595665769--------1-111122121111111----468A756CC78CCCCDD9BBBA999FDDDE8DCDB9EA84677979ECDBADACB4595755984444444456757499586567875641767776995AABB9F7776666555554353433433756574498588CA4A566977897D776676A86981115666321223B8C87B89A999A9999-99999899A999989A888BBBA9DB8A9AAAAAAAAA9A9AAE98899898-C99989999999442622212555566D89555544144436564B9BAA8767566DEDDDEGFACCEA9DCE64434554468AA7898899887777777779DE77773464887765--------3-1--------1--------1----11-35765646864856 -1219BB-B54388CBFEDJFJGPPMGGF9BBAGHEBEDDFEF9CEEFEHLJVNFGEDABBBADABA99A788AAA7899A99899658DKAF9DIBBB86CBBEI-CzClEIEGDD75498A8SG3I4X*A-CBG5B87E67E96A743B64J7FA9GJLI9VD8EA6E8CQQAADGD*CBDHEUPaiHYOEGNNLLJ -----------------------1-----------------------------------------------------------------------------------------------------------------1---------------------------------1--- * c.79.1 Tryptophan synthase beta subunit-like PLP-dependent enzymes
[ 165] -----1-----------11-------------------------------1---1------------- ------1----------11-1-----1-111--111-----------------------------1--------------------------------------------------1-------------------------------1------------------3-----------------11-----------------------11-1--------------------------------------------------------------------------------------1---------------------1------------------------1--------------------2---------------2--------1--1------------------------------------------1---------------------------------------------------------------1----------------------------------------------------------------------------------------------1-----------------------1---------------1-------------------------------------------------------------------------1213-----------------1-----------------------1------1221--1----------------------------1--------------------------------------111--1---------------1-1111-------------1------------------------------1----- 1111yyi-2126NITBADABCCBDBCDCCBCCBABBCBBBBBBBCBEDDDFDHGDBFEGGGFGDCCDE6FGAFBDGH7FGCEEEBCDDDGNHAJJLEFFFEJFjip4u5b**********************a************z******t******e***hevY*TY*TtdW23212-2141ADJFCE422AB9C2 ---------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------- * a.116.1 GTPase activation domain, GAP
[ 166] --111-1-----1--11242222161386563341--11121147556-1545-12112223332-32 25C2C1322341-323333-34223532333235552375-636731342323762-2--32E4555FA622333222-2243122-29CBB-4762--58258856-6I8DAD88333333334452322344256657-1-61994744545554424465747A665222222272222744641-588588888D9A6798DC843118187D414328C3333353663334342343333475564564666675564477774444444222223222323222322322223222233333323222242222518476222-11182534333444622452BB2-9851-314-1-311-384-78444-4444362454253633444244444444-974766526B7-766888A9E66A35222B3457764215555555544454534----------1111111121111111114-442645B8B8JFHGEE86777FFBD978848CLDIFCA--CA959CDC8D98J476G9B4783654446548AA7CD764344336233128996B956499F9IC56222222222225666555662313AAA88849264747756456677664A4664946127467---11-98756666666777766-666766667768766666685876664978879878789A888666677474358975988A565222413111444447656222263232232234AAA669967885EDBD7CEE7BBAA7DCE646145444466665557567884AABDCDD9CC66561--2554455----------3----2-1-3-----2-232-2122333622222222A22 4434UZ6-QI73897EDEEHFFEFEECFEDFDG998AB9B98ADDDCHGEGEEFDGHDIKHH6556552564575554765333645658F7D9689889887HGL4HsHPdejoobJGIEIWMmcDpP**m2oSuHPFHdOQRN9UIOHWJBeNPJNWBBD7CCFALDB9EIF88GC9z889P8****D**EPQbmdF -----1--------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.136.1 Phospholipase D/nuclease
[ 167] --------------------1-------------------------------------1--------- XIg---------------------------------1---------21-3--233--4--11--2--213-------------686CCTVVP-W46---6TBFBiNVEJ-------1------76445774359B211233--1-CDC9B7C3333422B68593V8EI8-2-----2-----3111--22321111111-211--2112114211-3112222------D32112221-111111111112-----------------------------------------------------------------------921B-------3-2-3331--------2-17144733417-1-----31R6MXFFP12222NVnXriMfhZeWS8CBC8CC8B8F-hqZUoegh9KH-ZLLLKLUMNHHLPeCKIA6KADAB78BIIIIIIIIFTSG9BLB2221222211--2-552642223331-12178HH9BC8AIVZcZdRNFDDDPPbYMMMMGPRPjNYWk-9bdXGONJMoROFOJJUZKSIJFG2222222FAMCOVFBK379BB8EH8861CM7FFJJDFMOKLUK5IB4222333344666776666H739IFJHDAZPESOKHCMPPPOOUYhUSXPOZndZR--2NKAM------GEBEAMDFGIHFHHIEF-CHHEEGGECGEGDFFFFFFQUSEE79ADB9BDDDDDDB9D9BBKC8AB9DC2-KHHHIHHFDIII--2B68666BLJKXHHA9222225233333333EEEHEBG565KGSTUTQQTTLTYVNIIJL222222222OCONKBBBBBFMRLJbZUPVPPDIIB8B835FDLL8BHH122-2--------------------------------3---21222HMB3 -------------21---------------------111--11----------------------1-----------1---------1-----------1----1----1-21111--1-1-1111--12411---11--1111-111-1111-----8----A-3--111--3----1------1--C----1H1--1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1- * d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
[ 168] -----------------------4CHHB-645---4-15765645-4M-2214---1-21------17 7HE2C33444444468B99-9922A8999987888858896979I533512214413111BA7-K2AFCD621121222-535216221121-3------31-1425C322222222222222-2122-113131BAAFF321H2ICDMED322441222413632EER8111111111111686332146CBMMNMNFGKFJGLHIHCKEEFEJHK69CVAKG566657Y*333333333333333444243222332231344333323222323233332222--2121222222233333233333331--------19KJJvDDDDCHDEBIM6JJ3775XDD--H6A75cbIHB8CC7443AH223AA5DFF92222367jkp876RXQRf55555554554-PLOJJBOf493-OJJfRNPUVWBCeA9456443A436G54444444479866*Qa11111111--111-1111-111111-----27913CC988GIIIIDSBABBAANKGGGG7EKGUBKAL11GNNMGQHDS8BRH5DPIGA7ALF3333333765DTU9aWAQBNMEngVUT3rgmZVmcMPOIHOPK8E332111111161411111111512233TQ5DJIK9G99HJNOLBNLLKLHDEJLHXO--23758------GNTOCKCCDDBCBBDCB-DDCCCBBCADDBCBCCCCBBAAPR437DBCBDDDDDCDCDCBCF979BAAB3-FBDBEFFBDEED---411111222266VCW222222111111123321232-112EBKKNLRVTeIPRRSOQRW---------DFQTUQRRTSLLSfdBDKKMKL9A91---11aMBB78BA--------921-------------------------31856553441B-1 -------------12-1--11111111111111111--------1-----------111111------------------------------1------1-3------19------------------------------------------------2----1---------52----------8--4-----7---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.274.1 HAMP domain-like
[ 169] -----------------------------1--1-----------1-11------1------------- GQw7*997776876FIHBD-BE33IOBABBBDLGFGLFPNDLDROQ445666F9A23811KIO3dDXemdD211121111C8B42444ceib1V761114N8GH*E*9s11111111112222132334433555HCCIE224TCV8A87777877776B89656I997957455659454595222442C9DPPPPPHLOBNMPMNODIFFFDOLQBABJH86433444kR444444434444444344235223333122133222231232222122223331111111121111111111111211111221112222COICPDDCIHJDHGDDAIG9887KJL32NACDAUSMCFDACA9A8D8733N1dPEEI4655579KGI7HAEDBNG6666666666C1GGMEHMFK8K73GFFDIHDHKJCFCGCA989AB9DDAA866666666466658IB2232222222334323343343443423538AFH49EDB9GIIKJGHDEECFFKIGGGF9DNFMCGCE44BBD8A6A9K8BBE59RA776EB44444445N579DD485234453864343675554746QLONh*39811111111131122111111312176576DBGHADA79AAAAABB7779879B89E2-3866923233364765776556655565-5665546466566666665666DC78655555555555555556546545633855555555555335C444446656359775555545555555555454457333KENOLNOUQRCKYJI9BCD2223222225688877777B9998IIC9D9A99A4444335589ABCD2232322254272G21-211112-11111--2111152555545446d46 11--12117-411412-2-123-12-2522-4422113244-1-1-34143-5--12-1244---111-1-2--211-111---211-2222-3251121221-23-133D38487443556A5CF374Up95D3I8455A457225711632769A793222484-323313342243B23134I8AI2A78865624 -----1-------------1---11----------1--1------------------------------------------------------------------1-------------------------------------------1-1----------------------- * a.177.1 Sigma2 domain of RNA polymerase sigma factors
[ 170] 11-1-12232223322-2121--11---2-111----1-11-1223111-311-1------233--11 31539668999777BDDBC-BC99DEBBBBBCCEDECDDG4A9GC78669A4BAA568337977C9BECF79888AAA4-163333333335-443---25222434231111111121111132232222224277787223A-A98566534554435454668587524222224222286744112221AAAAAABA3BABAB9352222BB9433825398898847-44333333333443433325A879976799BB9989566567544333A4447774444444444433333443344338554634445333482224221333124322226362-5432154223--2-12222344314677811111537764334642533233232224-8888985859719665BB5887776579524433227768888888846557343-----1121-11-----------------22632322223766767788876686788868758768513666775554565758663222531111111343453447234342523334323333442114166-531113111111-2-------11233333324535283353333252355343433531-3233411111155546457778777777-7788766777777777776776544646666665676666666554577772164444444444411331111122223672633334422332233355656452454233336665456655665112122-2121112221223433355888886663353-13255555511111111312--------------------1----132--121115211 6888EEF-sKK4DAKRSVRMQQOVRVPHHFGGGHJHFLIIEIJJHHSSLLQYUZMPNLIIIIFGKBHEAKJDHHGJKAGJBKMMMNGGGJdJSGJOFEGFDKMIDE1E*JQXXVaVaMKIIGNImlGjI**V4hUyIKLKXHLXKFOMFHRLFmJTLLOFILKMDMPgFNsZdHD9NOJ*LIMFLVNMWQTbdcdczie --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-1-- * c.60.1 Phosphoglycerate mutase-like
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n9-H8B4654765N44781565493554A6756A496E76C3577BAAB*CDC98KHKR5GEBAG8877 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.66.1 Alpha-L RNA-binding motif
[ 172] 22---212433423412112111-111223-232-11-1-----1----24222111---11-1---- 7AH-91--------11122-23--1111111223322262--43211-21-1213--1--222-3122-51----432-1114--1-1122----1----33839E5-32------1-21-112--E3-222E1-36655---64834-2612112-12121131466AA-1-11111----231-1--1-1-22223212-1311122-221-12-11-3--3-11---111111--1-11221-1----11-1--1-11-121--1-----1---2-1------22---1--------3-11-121-13---1---------1332222112-1-1-11----312--2-31-3261111121111-13-3-D233612-1222E6431-6546612131222218-1-8--511854-523A44452342972133453-224227777777762233932--1-------224-12134511111-----62B--25Q427345242222244265153349395926-1--B5222125117A1542-322311-------3413791541-2332--1-624165712-13-2522---21------2112232-33--13--1216-83-2-121F--28-211344-2332---1211------131414-1114143212-12137323311251-1112-31131-122-322121112122-1--3------121232123435--12------112128291----1111------32-11112-2361112213--4445-2112----1---1136-21421664--3131213---12-3--A-11--33---------2-1---1-----------12----111------1---1412 531138c1NF79C8EBNKKMHGGJGFNFFDFEC9MAFD6E8AA7EFMVDFQJLJE9FJCIDGBC776A359665997379568A96879AD7NGFKGBAJ7VB5AB-I9J********xjs**j**u*n***L***muu**j**hmx*uy*kY****s*Uhi***gUdpa***mE5962G44434GBBIHC6CI6MGP3 1--1-1---------------------------------------1-------------------------------------------------------1-------------1------------------------------------------------------1---- * b.121.4 Positive stranded ssRNA viruses
[ 173] -------------------------------------------------------------------- --------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------ IFGGvtZ-*QK5YbXMNLMNNNMLMLKLLKNLLMNNNOMMHNONMLHLOOMMNMIMNNOPOQKLJDFE6FEHKHJHIAIIFFGGGHPMPITHNMJNPNONHIPvxv6aRP********u*z**z**s*z***N***puvu*q***i**sg*xZ******m**sxodb*hjmasvlDLPDuEHAHJXYfuMrNGFWjZeB ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.69.2 Ypt/Rab-GAP domain of gyp1p
[ 174] 1-----1--------1----1--11------1-------------------11----1-1---1---- 153----111-----------1--1------11-------1-----------1------------1---------------------1--1--1--------121-11----------------------------------1------22--------------111------------1-----------1111111121111111-111-111-2-----1-111-------------------1--------11-1--2-----1--------------------11-1----------------------------11-------11---2------11-1-2---------1-1-1-1---1--1---1--------------------------------------------------1---------1-------------------------------------------------------------------------------------------1-----------------------------11---1-------------11--------------------11-----------------------1-2-------11-----1-111------1----111----------------------------------------------------------------------------------1-----------------------1-----1-11----------------------------2----1------------------111-------------1---1-----------------------------------------------------1-1--1--2----- 1-11-1A-6355654248563486457876646456886868779875536754345I4334344355222-3332412343233311433242145134161A26-313**********y*****u*o***l********o*********z*******JPqF***b*pl*Lmob-341-211--674564F1366GA- --------------------------------------------------------1--------------------------------------1----------1----------------1--1------------------------------------------------ * a.48.2 Transferrin receptor-like dimerisation domain
[ 175] 1111111211111111121221112-123223112111111113113111122111111111111121 12214--43231---1111-12--121111111111-21122672212122-1313-1--333-3332232---------11211122-----1--1---2-214-311--------------111-1-----111111111131222122111--------11112122-------11---3432211-1222222244424444442222223442321223-11---2211111111111111111111----11-1-----11------11------1----------------------------------------11-1222222231211-221222122--311-1222-11221111111-11112331-1111113221112222222222222223-22222222251-4443444446331321112322622111111111111112212--------------11--------------1122112212132221-111122221111111122222-1333-1-12-12331-221--23--------11122211113122111--1-11112111212113221-----------1---------11111112111---21111111111121-1121-21---1111------111122-1221111111-211211111121111111111112---111111112111111211111111--111111111111---11211-11112111-111---1--------111111----1-22121-1-111121------------1-1-1-----1-----111111111-------1----11--------1-1-------------------------112131111111-1 33118B8-qOW2ff*BEJGEDEFCEBHFFDDADEFDEEDECEDCABDCGFEEGEBCJCCBIDA45456134496444133857545778JEJEFEOADEA5CCbiZ-3*rRDMGJMJADE99CEKIDE7Z*G5IEVA9ACJ6EH79CA87IE9ODKDFE983BE9D6CBD287AACJDJ*QMNZP****I***qGZMO6 ---1----------1----1---------------111-1--------------------------------------------------------------1------------------------------------------------------------------------ * d.61.1 LigT-like
[ 176] 223331223433344123113--48349798322111111111334565466533435222-11-211 -341811122111-66544-46225644444568986443477855614531455223--575273437433333433--113213113336-411---1824464554--------------13454433156466656---72A596455646644312266679BE62333113312-1413113332-2555455561443633343312544-22313521111255-----------------1--1---1------1---11---------------1-1111131112221-------------1---------21314343332324151112221343--32131432213121122221-171G333311111334745345455422122222122-35634644333-4222315833333512352332245243333333342222435----1---11------1-1-----11-13343422142311222132112244453223122357663-13214553345624415722-121111111-121134252-1-4112-21-142333334922239B332--11111-12-2-1-----43358--223374315346222243334314347132--233-2------11-----111111112--1-111111121-111111-1----68--2---1--1-----------111------------------311111222246914-11--------1-1-2323222421555575144341221533321111111141342111111232265335334251111--31112234111111113--2332--1--1-------1------12212-121112631 B544MLE2K48267BG8B48788979EB8A6785568768766859DBBGAGHEDACDB989667334166464665275867856A646B98A89A9B5787GGN7HTE*********noq****o*z***3***hx*k*w***i**he*oe*t*vsyd**dlhVTpVakRlcS2HD9*A78G7UMXc7TNGDIHJLC -------------------------------------------------------------------------------------------------1------------------------------------------------------------------------1---- * b.2.5 p53-like transcription factors
[ 177] 663853A8A99A99A93888999A78988877AB9CAAEA9BABABBCCAAABB6A369528553-66 79787C9999968668877-76667777777778887AB8688678887796A9B78655667A9677B87A899A8B335586677788768811-3316677888671222212-33----2877767778679878899A878BCB9988699877987B689ABF87876788978778877777478877888887488888799998888978A8A88999899894BBAAAAAAABBBAAA997C522179133237711774221748873333534977AAABBBAB9BB33333333334339444464444873AA6665435358A8995433A182367A8798B9A84577889824889A77761211199967676777677777777777827777787877617777669776766C666676666777777777777776677681112222312---------------111267666666677666867866667768666646769876778777988767777886887CC9766666666666777399A68B88667774787A67776667676B88966677777558756556666776666787A777688889887899888799A8773-37668662666B888987A998AAAAA9-9AAAAABAAB9ABAABAABBAA88888BBBBBCBBEABBCBBB999999A981B888988788995518554358888B6B79ACC99969A98736B78767767888898998877888889777855555555799AB9999998B8B6677676888666666E688A965112111113------1-1-1231-222-45122---34922747776776 44-1449-EB42DA9A8C979ABFJDEFF8ACCBD9AD8CCAABAA8A9CBDCD7BA99BBC6999886A79989B98B9899A9899CAF98CDD9AB9AC89CL17H7D8988A836236537A3B4Kg9-757321554353221215234588884565B642345414D5DA98z8A889LHOKDNIACGAED6 ---------------------------------------------------------1----------------------------------------------------------------------1------------------------------------------1--- * c.1.2 Ribulose-phoshate binding barrel
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mHE6AACACBCACBBDCBABBAAAACCDBFBCCCCDABCAACCBDBBBBCBBBBC5BABB3ACA5BDCH6CBB9AA66EFEAF9CBC*BBBABABOJS6ALAXFNFGHFE8FBCJDbo7Y8i*Q1HJmBGBFJEFL87EHDDH98MDHCGEEGNBFDCADBDCDEDCFIFF*GFFDEfVgtCZKBEEEFCB ----------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------- * b.34.5 Translation proteins SH3-like domain
[ 179] 446466766777777544767663844747C7322463444443445349AAA224244545443338 8781222211111122322-23--44222224433322221323231111-11121-1--2211213342111111111111333433446425112--383A765375--------------173123434157111--111319LG7BA6333324366479468877151111151111112111134244545545525554654333445462222222332223241332222222223224333211111111111111111111--11111111111111111111111111111111111111111111111123222222222232323223444132112122222324242222222111217333623333433322222333333133331124-33333333454-75647769A899526567634444A584444444445553233--------11111122111111111----174545566579AA9A97655588B965666697B8A9B1256534677643463357452365333333322374356645233267221123353649512124813322323333223233333335453533993D6B96DC8877776B9777696996781-27426111111A9675AA9999999899-99A99999A9999899999CDC77338ECCDEDEEEEEDEDDE9988989842755555555565123623223333338667444323222223222444444446744CDCCB9CBABCBAABBC74543552448A9566666B7787765555555433331-1122333311111111211-------------------------22222222221221 IFCILLI8wJIDHJIMJJIGIIJHHAIKKKIHGKKIDJIIGJKGHJHIKKJIGIFHKFJIFGGBIIIGBDJHBHDHHEEGHHHGDDJJJGPKJKKMJIHIGHJNNMHKbHXQNQLPSGLQGKZMZcFhI**k-dR*HJKKTHKUKLKNLJPHFWKLMONKAFLNLJDOKKNEOMKLRNP*NLISOuXbyHtSSLOOKKK ----------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------- * b.38.1 Sm-like ribonucleoproteins
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b8H9A9E78PCBE8EBB8*988BFJENQ8I9FC87546 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.84.1 Phosphoglucomutase, first 3 domains
[ 181] 331114221112223131322224644556754-1111222226355557C58-4224363444--34 96B6A44966745387799-B944799899979999A9EB698B978775548A87463377A689ECFA732224224565966455888835663--56675B7996222222222222224775766665768777766666979888765774453376866889743344443443588977346777BBBBBBCE7BDBA9CA7AAA8AA8989CA67766668896999898799999998A89843444544343434455434564546555444444468877676678244444445443444455444445A68877778787866876555556755C658799977758886775434859566454454679C9A68AA77877777776678-877978898944A76A8AC9A8985745678A788887755555555488358664454445544222222222222222454445675467767677876776776686989A69957A9D9567767B977A565A6AA56655754444444587765778786888676663CACA99D9B999A8E9A554434444332422222227954777BB6343766577788878899A989877884-3844444244478887778778887888-788888888878877877888897987777777777777777688877778638777777777774444666557877845976666766666665577778757566667787A986A666879775555555554789887797899A889998988995555556344454411-1111131411114-122122111122112211144455655558C57 4234GCB-C444AA8ABC79A99A7BA9958897887988578797797BABAE9B98A9898687784778679896B98677966877E7B7ABBCC95A8B7927F59DIIGFIDEE9BL8TMCUDt*O1ZRU7DCCLDEKIAJHA7KB8E7GD8BA9F7C785A78PAEJ79A7AhAAAC9KBFd9UEC9CFIE8 ---1---------------1---1-----------111-1--------------------------------------------------1-----1-----------------1----------------------------------1-1------------------121-- * c.97.1 Cytidine deaminase-like
[ 182] ------------------------------------------------1------------------- -----1------------------11-----1------------------------------------------------------------------------1--------------------------------------1-----------------------------------------------------------------------1----1------------11111111111111-------------1-------------------------------------------------------------1--------------------------------1----------------------------------1-----------------------1-----------1-111-----------------------------------------------11-----------------------------------------------------------------1------------------------------1----------------------1---------------------------------------------------------------11-----------------------------------------------------------------------------------------------1-11--------------------------------------1---------------------------------------------------------------------------------------------------------------- ----1-H--1-1ABDACCAE9A8E8BA9846577866A88688867A9BAFFB*6BBCBGGGAA989A5A889B867477689988434HI9CEES989A49Dhit-Y21*********wq*****j*****6***h*un*q***g*wvh*ua******epl***mf*hv*Tu*S1A42312-26****A*w366766- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.38.1 HLH, helix-loop-helix DNA-binding domain
[ 183] 112---21222221--111111--7331-1443151-23221-4734855548-1----21131---- 31143337557433522AA-AE22D2AAAAA7G7A96735-1432625633222B-22--426261734623233344216-313-233442-411---23233242431111111--------342334132-323365--1342C856872222-1----7924A943----111-1---253441234144434348433455743111344362113212655556321111211111111112211-974478438586622986145446553221111244212221111122211222112222221443222132344899787858538874463735213-13544736533-276732211316335-1--1564385165543233333332334-48426869437-3333323733365B1429-5665611422222222442-2444----------11------------------2523121---355444265665544677735678464922BC53438764264-637433253222221211555511422134351664-223334234577437631-22-2222231121-112111-223434522211222111111213222311-231---3428------23222421221112111-211111111121111111158521-2-3332333333233323411----1--433333333333--12-----12348-411----11-1111--11111111222254666836452333233231111-11-13---------1----3211211111------2444--12--------1-217223-112-11-1---11-1---111311132112453 C878LNL-fBA9HEKHGIKIJJFGKLLGGGGDJMHKIIFHFFGEEFJGJMPQYaJMMJJLJKD7B8BA1AE89AEBH3BF9CEDABDDCDQCGLDJDCCACDFSNS1IMZOn*o*twVSRUeeX**Q*X***D*o*LWTRqRaxcKbTOMqOK*XzahoMf*cKGRG*MMxPeJC9HHB*789DCZZe*JkRAAYeSWG ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.33.1 Calcium ATPase, transmembrane domain M
[ 184] ---------111---1-1---------------------------------1----1----------- --1-1---------------------------------------------------------------------------------------------------------------1-------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------1-1----------11---------------------------1---1---222-2-2----2-----211-11-----------2------------------------------------------111-25111135444433226666153412222--1-11-1--1---2--------1------------21----------1----1-1-11-1-----13---1----------1--------------1-1-12----2------2-----------1--1-11--------2-1111-111-22221----1--11-3121-----111111541-21121-1111-1-112------1--155555545654---1-----------212----1----------2212221---2-3333112222222-211122222222-31221111114322--1-2--222------------------------------------------------------1--------- ----FF*--1-133312321111122333121321223223111121211132623121121211211-21112111-33122122111321231122212-13142W-4y*********************6************z******v******u***mSRY*ce*m*VR-131J-11-262582623335341 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.93.1 SH2 domain
[ 185] ----2--11---112112-------------1------1---1-1----11----2--1-2----11- -----------11-32211-1---422222233111-222---11--------1-----------3-31---1111--1--1--------1-1112--111-1-2--11-111-1121-----1---------1-----2--12-211-23---------------1123-----------------1-1---------11-51---2--1----11--11-111----121---1-1--1------1-11-2---------11-11--------1------------1----------1111111111111111--------1-2-----1-----4111--1---111-1-1-1211-223-1-------112----11--121211----------1---1111---11--1-1----1-----------1----1-1-----1----------1--11-----2-1111---------1------1-1-2-----1----1223211------1-------111-21--1-----1-----1---------1----------111--11121----1--1-1-1-11--------1---1--2----2--------1---112------21-1--1---11-1-----1-----1--1-1-2-------1------11--211---1--2-11-111-------1-1--1-1------------------1------1----------2-1---1------------111111----1---11-2222331---1-2--1-11-2---21-31-1-1-1--1--211------11-11-1-2--11-------1----------1--2-------1---1-------------1----1-2-2---11-1- 2135WVP-NFH7POWKHLIHLMLKHIKGEFIFIIHJKMJMJLLGGJJGIIIJPLKKOJGJKMDCBDFF7BECBCCBBCFFAJJIBDHJJBQCHJJNBBBC9IIWWP1c4E********zun*****s*t***O***j*oy*t***j*swo*lg******b**ujZSPkXf*QtkY3886K89722MGMOLLF27BJID2 ---------------1-----------------------1------------------------------------------1-------------------1-----1----1----1---1---------------------------------------------------- * a.238.1 BAR/IMD domain-like
[ 186] ----------------------------111-1----------11114-1111--------1----12 342-21--2211-1-2111-1---2211111111111-22-132--1--1--221-12-----112212-1122221212321-113211131411-11233724322311111111111111-1211--1-16125534---329AB8BBD79AB5656849594FFF7566787787756---11111-11------1-1------1-11-1--111-1121------221111111111111111111121-111111-1--22111-1---112111111111111111111111111111111111111111111112312411111214244143321231133-32--42322121-21112123-21122223222546753324232254445444445-34534434455156665644755543322312212241233333333322335433333344423222122221222222437631221311112333333322223324222222333222232121421111412312342122211222222221623356222411422212435-244317768G7343223222222311121111143312225523634365534444454444434334341-3412122122243333334444444444-4444444444444444444444333444444444444444444444444442133333333333311224543332234141333334344423233322342343334344444453433333566211111111365544444444544221212211111112142434443333333333-1-1--3-112-162-11111121--11-111111211112 eOJLPLK-*Zd5RWLKIQRKPLHLLIGNJKJINJLLJMKMHKINNMNJIHHHKJCIGHKKMMQHJDIJCIGFKIJFGAIIFKKLIJHLLHXOINMQHHHHFRGPMT8Q*NlkhfcgUUILNMaP**N*Q**k3pctMUQPdLRjVPVSONaRNpKZVVUYeZTSVSEfOWzKTTRGRSe*dcRQPyx**I*jVkPTRWl --------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------2--1- * a.2.3 Chaperone J-domain
[ 187] 11--------------------------------------------------1--------------- 1---11--11---11-------------------11-----1------------1--------------------------------------------------------------------------1---------------1---11--------1-------1-2----------------------------------------11-----11------------------------------------------------------------------------------------------------------------1111111-1----------------------------------------11-------1-----11--------------------------1-1---1-1----1------------1-----------1--1---------------------------------------111-----1-------------------------------1----1--1---1-------------------1-1-1-----------------------1--------------------------------2----------------------------1---------------------------------1-----------------------1----------1----------------------------------------------------------------------1---------------------------------1--------------------1--------------------------------------------------------- HFCJdfZ7yJNDWRYUXbTSUUUSWTVSSSTPQUTUQUTUSUVQORRUUVUSVUSUTVUQPQQJKIJKBJIFIJJKNCKKJHJIIJIJJNiPXSRSPMOSKPMTVY9X*f******uoitmnzn**e*j***3***kmjo*ip*kbppkhtnn*k*qpyhpfgyreX*cizUdygLSSN*JNMZUpq**T*kNPOURRQ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------5---- * d.20.1 UBC-like
[ 188] 224121454444554531423324A4579866-131122222-441-21-1--122225232222-11 59E5C-27556121FAAAB-AG11HQAAAAADHIIIIEif585C34442322A69732--A6K29DJCCB2111111112267342332232-422---4645792B46333333333333335655667466877775643568JGBCDD9797788AA77BC86C9F955445555544555522332324445456453555555433314554254411111111154222222222222222211222----------------------1----------------------------------------------2C8156666556748465411115143572167BA89AB455822231--935967622222CJVWi84BEECJD55665665649-IINGHVIQDG92HDDDC9PHDBNTJK665DFEFCEFEGM88888888H8949B553343333333333333333333333333367FK62COJGGRRSVTSIDDDCXXTcFFFF6HYSmTdXQ48KJFNI9B8MFQCVQ8FE5767886676666535BNH78D59443476554-4854B65786656DB6H2342233332332222222245444BBA97965E5B5BABBBB8CDA99AAA99AAF2-236662323337979875CBB9C998CB-BCBCA89CACB9ABBBBBBDED8A9A88788788788788887F9889999418BBBBBBBBBBB3324222223444D69BD444846344443444CCCCD8A596G3KKKLGIJHHLLJJ9EDD22222222258A9D77777A9899447989944422224344441122--------211-------------------------33665232223724 33-1334-K741443846434555555555655545454445445544569686556555553332222332243231222333332223544335454442345516T6N7D878D6636585BI4D5Ib9188B3636B56B447256G34F4A7866BT6DB7BCEHCF887ADF9*978E8LJaW6QM9B9676A -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.15.4 2Fe-2S ferredoxin-like
[ 189] -------11111111--2--------1-14------1--1----8--12--1-1-----1-------1 B8R-R33545549489955-56228D5655578AAA89973DBC666B3CEB9GD38A118865SA9KDDA77776443-44211233HIZP-E331--7H578J8c2S1111111222----1-1-2111151-2221211-3399BB98433445325446516A9HG5332322442451111121184867777786879777955AA8967934573536777775F43222222324435212333342355445557855555544334576444233244222222222223333334433333244432444455-657775784364B4882654C493-1A41-554161211222231225-YB674-1111E88DC8678776B44344442234-A7EBAB7G7971587598D88A8BBD831C4544448555555555547924732--------1111--11------------125874452222977A796BBBB88D7CCBB7B9C824431143645856444654445213294574676623354339622123-M611423222522235746BM234-11-33233123111111111-112234346E52E444544444533434654369---63321--11156582434GF5464645-G34358B559F7544444445345666545354544443533444632225-13222322222321114-----67765484622222312112224365567435455D8777C656764636A67B65567446154572222254657C9EGEGGCBC33331163FFEECC--------322----2-23121--3334-42132242112-111112KL8 1---459-3-3156FE8KHGFLAMFLL7787BAAB76444554799BGBEOQTMINJPDBAB614334314233323244122221322AFD8IIFFBBA9A2PGK-B*DzZLM9IDB9AEDJCYXEQBx*L-QKV5CDBMBFJCCFDADKE8CDCJE*CEQGZYB589CIJMY44KK7c957bNu***D**ONKGHIb -----------------------------------1----------------------1-----------------------------------------1-----1----1-------------------------1-11-------------111---------1---1---- * c.23.10 SGNH hydrolase
[ 190] 11----------------------1----1-1-------------3--1-1-------1--------- 2582G533445213EGGPP-PGAAV9POPPPEIGFGA7AA1T9P2123122132323411KH62i3Nh8f333332221233123222766615336--46245823361111111111111133336543333443345222R246C655B22111111112218DAV41111111111111213332233A44545555755565533228755733453-111111173211111111111111311311112222212111222312211121233311111321111111111111111111111111112221111322444444444444A4883333433-25322222222332323342333525855311111ACE796467A55644444444443-88I8AD9858217558348455546E452536232253411111111443216442212122222112233237333333212412284134423AAAA9GGEFFBCCABHIHH6GBA9BDA924799A8654878B6767B21139522232234454676642243533322212326349357888UI15-112211111112111221122324328725564474578979776976776667661-25545111---A264462477A4AA744-75455554667754444445466375446444444444444444444445411455555455454111323324CCEE36D23333343211122--2667765842385565689564455556473111111113455D4335356744333333322222221123AA4455--------212-------------------------24322333331714 64AB**9-H44-889KPiHdSVcntsWCBDEDENVHJRJRIMMDDFQURbaSaiKQbcMKJLEDA78A4BC7A7BAA7AB9BDDHGAAC8I7P7BA56346SAB981CnC*IPLPRNHDCCDOGPPFZH**O-TKkADEBPGIOEBHEC9KE8RGRJMGBEUGJM9LHAHMNMKO6BD9mBCACGKOHyeLIAEEFDCH --------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------31--- * c.19.1 FabD/lysophospholipase-like
[ 191] --1-212245644444381221--1--3241-1-1---------3----1-2--1131221333--1- 8AF1K-2211133122333-3411643333334444243222137B72386-77822B--446A62ABH6353337BA2-1-5---21HHaM1B33---8H175F4C1L--------1-----1221223222-265578---413254443112222223222366884131111141111432116856422222224422522345A5533222324-144DEEFEA6P23334334333333332223C8839834769CB558A3688749883553434421577765656763333333333323256533433394-CB2223222322E7434AC9K352--4B-1314---D-1-777A-113136444422327446554222-1333433344445-776994353B1-799B975CC886-221122464362532222222234332114111---------1-11111111111-----13-32111127888A571111555643332455B4334--9974352224626343-62145--33232313433F2-121-42-1311-1115--13-132223A111111---1------------2----44444629518245664734476655855535---3-11------AC86694DBBDDBBBCB-BCCCC9CDABBBADCDEC6B9965115CD98BBABBB89B98BA976BBBB31944465545677----11111----42255544537-3432233311111-1-116A43442668466783AB941222422112558576675679D327B8A78881111--22221133-----1-11-4----1---2-2--11112--11---54663757971G83 2111CFI-JC79876KESKMKMHJMMSAAADBC7A79978997999JEGJMLQPMNJHFHDF68E5851A57D6C7C6D86DFFAH535HLDEGE686965G8DCD-CQWvLaUhSUHEKSINJVfNeL**X5gSpGOLHXELSHHGLKGYIFdNJKJOHazKLRlddRUkEOKD7IND*AA9EGcjz*Lr*67RRST7 ----1----------------------1----------1-------------------------------------------------------------------------------------------------------------------------------------1-- * b.30.5 Galactose mutarotase-like
[ 192] 11211134333333332253433165653356341324434231121423A2241-1211-442--22 6664943566554786666-6622A866666786766767457955544452676644227656967888822224333326463566554527662125445467554222222243344448975B978598B6446722164A888AB795559878877668777879777669678665644244586888888889A88A986666668A75556643233322A6466656555566655645543---11-----112211----1-111-------1111111111221--------------2--431----47474444544454564444444655234553144E4224543553233456A54543334253554545455353434334434515575545546334555546564545464364645446554444444423344674333333332243333333333333344443343365444465565746666666866765566655464745548766776574465445344444444465356768A8A355559664298A87866B33436956632343333343255555556246845445575534655666655666676677786214566511122265545444444444444-44554444444443444443555556455555555555454554443444433544444434444-14522222222265759333334144433344555554544436554555554575576456555564554565543343454664446365454444433755577761111111152-------------------1------13344433434743 8766EDD1ZDG5HAIACBBABBBB7CBBBBBABCDBCDBDBCBBBAFBBBDECDBCBBBBBCA999992A979969A69999AA99BBBEKCCCCGCCCCAHCGCE4DTBYUZOUNTJGIILKIeXIaH**Q6eTrEHHIRHKQKDMMLERIFbJLVKKIZZHHBGJLHJ*LIODBGGR*PLLDIOKPZCTSGKCIITL --------------1-------------1---------------------------------------------------------------------------------------------------------------------1-----------------------1---- * c.92.1 Chelatase
[ 193] 33424555555555555733333132232423336556333433224323232434353425343-44 9B85C42333423234333-33225B333332687834A966637D443645B4A22A2298557BFBEC533334337323644444437423432--36554A875633333333334433444555655456555982334765374455355444344473334683453433623429874487623A445465666566566DA88B85557597957DHHEECC54888888888AA888B6689J963BB33A3ADB22CG54B347CBE3335444433544555454544444444444444468222766A472AUAAABACA8B63H44475656573836322232224322759366574446643333332868645534568888888788F-666786679J52F99AAADDBDJK845535AB88797A8444444447775455511----------1111111111111111142553577777HFGHGHBEEEDFEGFGHGGCFIIGBDD94499A84766C6AAAC55456568577667662435443864344535554565658544645534674655453666574434444445554545597B86684A6877666655777666556562-44543321333JE9BCFBDDDHDHGGCC-DECDGFICDDDGDEDDEEDMILBBABHHMFDGGGIKFHDKDEGIC9BBBBB73DFFEGFFFFFGF3364777675445749C87786877787598983334343343B6A9A89DAA89788688866666666649BACAAABA9C9CE6744444444444433576655551112111122311114-4243711333162132---3A6535E5558A34 3423478-C43255564545585685B5545445443333344333467446697576479855343413424434334334334432247F432343234733562657DKDCHGG9A94AC8QI8K7X*H3E9T5856D6AB96D8A7C64G9D9BDAHK7E496C46I47E55492c53344HA9L69J9C92447 ---1----------------------------------------------------------------------------------------------------------------------------------------------------------------------11--- * c.80.1 SIS domain
[ 194] ----------------------------------------------11-------------------- --------------1------------------------2------------------------------------------------------------------------------------------------------------------------------1-------------------------------------11---------1---1---------------------------------------------------------1------------------------------------------------------------------------1-----------------------------------------------------------------------11--1-1----1---------------------------------------------------------------------------1-----------------1---------------------------------------1-2------------------------------11---1--------------------1----1------------------------------------------------------------------------------------------------------------------------------------1---1-1------------------------------------------------------------1-11-------------------------------1---1---------------------------------1---------- 4311eeP-QBA49CH7776576668776666666668887679777786688769555756665545414534564433446554556659478474446556IFG4OfR**********************H***r********l***y**i******Xo**imXW*Zd*Zs*X2879e44446DAAK6HM32CFGIF ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.40.1 Calponin-homology domain, CH-domain
[ 195] --1--------------------Hf87G6IHW--C-------1**2h*5MrPV------2----1-1- BPd-53--112----21----211-1------221233631-38A11--11--13-----118-82BHA56---------829136128775-711---2E193KMPUB1-1-11---------7457A12DQZ2PKJMIKACL6rPh*KK4CFEE233422COFAow*D34A944444994N241-2124353332323344343441266644546466155-111-1HA-11111-1--111-------1--1--1-----1-------------111----1-----1---1----------------11111-11112E24H1112122426-743111-2-3--65183BCHC7Q3A4332621--H4LCBBB23342B6POTC63PMHFN33333333335-nhgnbPtxAGF3EEELMHMGSLGIE575D362D9CF8522222222251153dKN111------------------1---2-21-5583133314E8AC9975445CBJN566513ACHBGE412CCCSFM9AJHHQ95ABP96FFOB111111123DKRh8*YPHMsb8*niey1ud*bNcZNi78E8QpUp4-11-1-1111---------67-3A11E93A7AA8A7DDAB9ACB9BCB8C9BA8BE--17CFD------55562635556566664-46557355844555554543332212-3333233333333333635222361-C23565444566---611111465565I4A111----111-1---333331--1-5DJKKJGLOLCGGJGMLHH-----1---D223189889887BCABJKKLIAAB2323-1Y-NNBCJJ1---11------------------------------22--211112-P14 ----52--2111--G47B81343-3-111--1212---------1-4834765A4673243421-11112-1-2-11-112-----2121127-32---2423333-171224457311-11224411-5H41416412122121-21211223121172--1323-312831722131-1-2-6D94Q87431HGRK3 -----------------1------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.55.1 Photosystem II antenna protein-like
[ 196] 332433255555544454646445A344256937733345665AB59B77HED224224332418-98 3696b-13335322dWQHH-HT44SXIIIIILZXcXXXot4bEfDI452743DGB536--GFD2O8SOWV912222232258C222358976-933---24355C675411111111111111-1--32-1-241888AA1-198FCB9CC966666666668844HHC556565556565585A562145256666646746757575876265653446333433332C5133333333333332543221433453-31244-1552-21224442231111--111112111111121111111111222212111121756B9A889B927345881222D2711342315865432155---1273626E5562422367MDF665FB9D85477577577A-CCECCGCDEIA1JIIGIHDKJLHICC6676FEA7AA988434444446332697C3332222222112232222222222212226D55199889EGILHGG8788HFMKBAAA6BMDTCPHA33778B9778B5EBG64B76557943343444112BA969954364398536-CCC795D66CB9C5E75634444454442522222224423557544958A596439666564544534435261-11224------67973655665555666-5657665766657665668BDA965556666676766576666A445666632744444444444222111221353343C59666135523224435868773933473ACDBECECAAEAB59981--------444333333384657875667646521111114554344--------3----1--------1-------------33-11242223445 111-216-512166CFDFGIEJCMLPKBB7BCA8998989AA8BBCGDENINQMC9FC9C8987B6783784767G6876878899444CICD9GFA988689555-5K8G456683653356486275Bc6169H2856433453525553142554663558444A29E54733CA8*675CEHBLOEBCG56A885 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.45.1 FMN-binding split barrel
[ 197] 4444434666666656544444448447686734422222224A444666C88222244434444244 2323213334343422233-33223533333332222453376721331111222322112222423221111111112133221-11-1-222111221222221-313444444565666662221222222244444222244444444443334434344366464444344444434121222222222222212222222222222222222222222222222222222222222222222222232222222222222222222222222222222222211111111111222222222222222222222222223222222222222222222222222222342A44422244222221221511141222244A68365444442222222222214466462268125222758872A944322222624621111111111433112211111111111--112211111211211112422523111354666542222442344444554923422266224222242424221222454333333322236211111232324232221212222244454463222222222121122222222-21122222121222261222222211112122222222212221211122222222223232422-2222222222222222222121222221111111111111111222222222222222222222222222222222216222211122222222222222224222213222222111122222111122222222221124444423254232212222233231222112222222222221322222-------21-----21-----22122222221322 JLIIWXIIzNOJLKJHJJJIIHIGIEHIHHIGIIIJJIIIJIHIIHJLJIJJLIJJJKIHIIJJJIJJBKJEJGJKKBKKJJJKJJHIIIQJJJILIIIIJJILRWFHUVeQlOMRMOMNISTLakK*B**j4aaqNFKJmJPhNLONMPSLNdJOLLLPeeJOKMJhKMhHOXNPMNJ*PLKLLsYrwIgVJKKKLKQ ------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------ * a.129.1 GroEL equatorial domain-like
[ 198] ------------------1--------1--------------1--------1-----1---------- -1--1---------------------------1-----------1---------------1---1-----------------1---1---21--------2--12--1---------------1--------------12---------11---11-------------1-------1---------1-------------------------------------------1-------------------1-----------------------------------------------------------------------1-------1--------------------------1------1121---------------21-----------11111111111----------11-1---11-1-1---11--------------------------------------1-------------------------------------------1------------------------------------------------------------------1-1---------------------------11111-1--------1----------------------------------1---------------1---------------------------------------------------------------------------1------1--------------------------------1-------1---------1-----------------------------------111--------------------------------1----------1----------------- 2312112-31111-3-14-111212121232-11-12----11-1-11231342112-----11-1---121--11-111---113--112213111111221111-232********vw******z*****6******u*****m**wr**i******McOc**EDNEHKDH**1--271-1--1231252--13-32 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.77.1 DEATH domain
[ 199] --5-821233323333673434212--4-62----2223531513-2513DAC67778867223---- 6DC1I4243342-187944-48447F444446AACA76EC3A9416231441AC9143115766666IKC62222333-32391626844941A333--3946169816111111111211113-1--223114-699AA22178B89B77677227453546656ACC5141211251211775558A4758FEFEFEHICFFFFGGAEAAB8FFG78BDB46889988LP23333333333333311242622-23-3---65--4523211-444321633342223333223333445534456453424533144426A7HFBBBBB99BBA7HDD9DCDG9512C349777A894788955756537276442-----44LGH988DBBAC5545554444A-E8G98DBBBB51IDDGCBDFEG9ADA86367444457745555555544473C2411---------11112-1--1111111113237426AA55FAAFBD7877688BA9A99689ABB9C8138886565478787A25B734382--111119855AA347234783876686ADA8CCA79AB79BD5B34353242431131111-1135457892237A9958564344423242233423446---9666------659645488878788B7-8989668879875888889777664457777777767777777867687895166858A989889--1522222566662654222222-2222122176677461227BAA9A6CFC35766489822212221223446443443323465433336684444--5532334411111112421----1----1-------1-------33445454648333 1422BE4-2-3-bTMA9MEDBBA7D796655568896767675867998BBFEPCFHB8888323433274344755336322235132B9C9OIE777D9LBXQh18EDSHGIPGIA95BAEAEO8F9O*D2CFD6AB8G99K86B7ABJB5NCDDED8EODRIRFPEHfEEC71143A24-W2D5BDJBA38G58C4 ------------------------------------------------------------------1-------------------------------------------------------------------------------------1-------------------1-- * c.6.2 Glycoside hydrolase/deacetylase
[ 200] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----32------EFH**************szu****q*p*n**nol****************eqxPfcEdQNvVrWWIXZWfnmltGBIZng*d*uyw*jKO*VjQ-AM*----------1-11----113--2--111----------121----------------------------------1J-*--13----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.38.1 Zn2/Cys6 DNA-binding domain
[ 201] --1----46676545212--1---112-1-21------1-----------1--11-1----122---- 9BJAr545445556CBC88-8E55AB888878HBBBIDHF9A7FGB33588457522422BBN4JCGTXVD311133233C7D56686DDGB2B331222B658Y8M6L3333333333333322-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-887785767887867766897877788899B78989A7999B8B74664777498789978789733685555588884398C5555546444455554444455343B9GHFGIIKHCINDF89CB3434344345B99B77777A8B77FF79698876444433675566553333333374231623-223222122223111222233742434545K33 S1--1--21-1-3-111--------------1-1------1------1----1----1----1-1---------------------1-11--1--32----3---1--9-312---23-43111--11126---12-333---1---42-134--1134--4121----11--116253T24366DDHM2D5BB8-239 --------------------------------------1--------------------1------------------------------------------------------------------------------------------------------------------- * a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
[ 202] ED428CHHSRQROQRQH4GE775Q989B8HB534448443443A347K436455JFBOeA74448463 EAH57312222311345hg-h72235ifigi25656533356E765282232343112115443444535211113222273242841332213233--1114112F8322222222222222322L45A24H222788B11154EPGLDHl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kBCCBDJAIEA68RAUNLFJLKFBDDAFCKKEPCf*K6OFQADDAFBDJBCFDDCFEAOADGFHDAGAMHJCDEEH8JP989BCgAB8DBPBGHDIG8CDBBG8 ---1-11------------1--1------------11111--------1-1-----------1111--11------------------------------------------------1-----------------------------------------1-------1-1-1-- * c.120.1 PIN domain-like
[ 203] 11142222333533414D33453331154551323655444546556543443144253453444221 5Av1D1-4AAC21114422-26335F22222396767AHJ822EGEH23835KKK32B226759F9NDJE522222332234A2122166CA2N11111-7-4DH4g5Q21111111111111235443342214977GJ11155221347--1222331-315-143311-11211--12157175983C4A778788793848774IEBB5A8874AF5922799898AX54444444444444423345716166142128944DA54545443445553331223445435233333333435333336761126666B745E555444645585444776D7332466317826315357865D11284T84451221774FAA33664344999999999AF-43643C54DO2-cQQFQLZXWTROA633166D8878D7444444444844313261111111112-1--11-----1--1111112HD3255435BFFFGDA7665DDED99985ACAD56545466AF3244C9889E343332344222222233244522753342273546-7A87659745345172511121-----111---11-1212111143957A42B3644456323333355454462-22423221222BC8D699FCCEFDEDHG-CGDGFDGFCFCCBGGFGGEMOPDC695E7B8AABBBEBBFB9BHBA4BCDC3-6BBBACBACAAA--122333344442476955596A5453577654443445223G788795C9D577696DBA1121211112322B4444434366766656545522321121221122-11-----41211122-232342144422424322126353558885I52 3423134-62327A247A89DACDBEG7869653366765377654C686AGB97A6A98853134221223212112132444323553E4755A77937F545515M4PDBBHG88C889D6E99P7Y*82IAMA59E895B9789AA987EB77AK87E7D8GL515H57824264M32527CDAG9GE85IuCD6 --------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.1.15 Xylose isomerase-like
[ 204] 11-2--2222222223-3242222422443364333322222223346335653321-1113113-22 6594333333433467644-432246444442466655B823355432343335433211544224763333333333246564444466974633-1257345665561111111112111145554444646444454433637776666455544544447454464444455545445674443345576666666675756678687765586586644555555453555555555555556556632223324322332222222342443222212244423334333333222223222222245444444424855577677777766855454343553A55436743455774677553574A766746556A7F9A6599B98967666565658-8CD89G888784988678FB9ACB86556B8DD8BDA6966666666BA95696844335333431123342332232232222658654CCBA9DEFGECC8789EEBD888859CBJDEHB4688ACA9BBDBAEEC88B5745865555555665AAB44557567546666299A676775898879875635556555346343544555455667696789467566666677788667766862136B761221128699676999C9CA988-99889978989A899899A9BB896869788888898888889788866695277777777777733344444376885C876333648233325656888884656777AA9A78688877789984343343335566655555655555565555766666644433445551111111121121112-312224333322222222245633645554653 3311446-A422456AB7AACCBCDDD9996888B97998789856678CCADB8B7B968666897757B7896886778777883696CFBB7A96855E8BCA1978ICLBCJH76959C9B87F6h*D2KBW6869G7BCD79877C78DB88AC8DBCDAH8P99HAFH858B3e32467OJOV7T85499B96 -------1---------------------1-----1---------------------------------------------------------------------------------------------1--------------------------------------------- * c.77.1 Isocitrate/Isopropylmalate dehydrogenase-like
[ 205] -------------------------------------------------------------------- --------------------------------1------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 3222412-2-1-----------------------------------------------------1---------1---------1---------------1------21D***z***upsgu*q**y*s***3***r*pz*****S*kYf*eX*u****ARMT**E7EB9B68**-**-2---x-------1----11E ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.170.1 SRCR-like
[ 206] ----111111111111-222222-1--4---------------21-13-------------1--1--- 13B3F3333333335DD99-9533F5898889678793E84FCJ4763634887B333334454434CB84555555433373-----1172-311-----1--2-1-1222222222222223--------4--DDDQT---E3dFFNEDBAA22-1-1119BM6FDDG-------3----2-1--11-------------------2211-1-----121--------43-22222222222222---------------------1--11-1----------1------------------------------------1115311111213112111111121411-141-22222----2111---53-B----------2111----------------------1--2--12--21121213221-11-1-1312341--2--------2--------------------1--------------2--121-122-233322312332-173333312215534------45523435353228-231------------86693-44----1-1111---2---1-HHDHq*-4-1----1-----1----------1---121-1A211--11-1-11-----1-----3--1-2-7-------1-21-2-11--11111-1--11-1111112-----1---3232111213212232222121---11-11-233343213343--13--------1--9-1----1----------111111111117332311115111-2221-22221222-2121111113321111437335541131--2-112211------------------------------------------------2- 5778OLH-XEE7CBLBACABABBB9BADEDGHICEBCDADC8BC9BD9DFDCHDDDEDDEDBA8BCBD69EB9AAEGCFGB9AB9B897CJCAABFC8A9778JMN1K*C*******gVbZgeb**U*Z***C*v*UabVtXkuhOlaTQxYT*dwagqOmwNcZSLpOOYGUYO3GFHfCFBFCJKWSDNB98NPNMI ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.26.1 SMAD/FHA domain
[ 207] 33112243344444851465553376664467232111111122332334545133233224553133 4485A34766734374444-46335844444476666DNO488D46583224A9944522979769BB8963333333433682233256553544621476764355734444443333333333244223343555662234545545543333333333443466552323222333238985533386B8888877767678777B99997787887754666666674444544544444444444562225621132882274342433434444443344333333333333444444444444443333333343735455554454454577443545434845235633445743557433553676675565564D875443333378787787778-65B44D468643977586B96A7868566568555577B444444444443456533334333333333333333333334434468B7377786B899AB9777899AD7778678AB7A9723776D65677AA5B5465354545464555544364585735545444564296956785455556C55445443333343433333334445533A97964A777867676668666666767672-4865523222275757768887888888-8889988898888888889BCA66666978799999998987977878788517888788687772346555559A9A865774345754666555566666657665A68888899BABBAA68886555555555455755554555565555555555444433443322331111111141311121-111-111---111111---34523434444744 3432778-G6564578BAC9EECFEFE8887789767998898777B99AEFEE9BA9AAAB8896874877889884989677766888HBB7AD8888A77GCI14DBCEHEJJC9999A99DA9P7c*C-IEDA896D78E978B99A99E8CABA56A7A758M8CL66766D98*888BDMJVX9JI89FTACB ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
[ 208] ------------------------1--11111-1-------1-------------------------- 1431123333321322122-23112222222333333132111212111111232122--1131311233311111122122111212112211111--11111112111111111111111111111112211111122111113222222121121211122111121-111---1-11-21111--111111111111111111121111111111121111111111121212111221112211111221211212221111221111111211141111111111111111111111111111111211111111111131333333323221112222111111112112111311111111112113122111111111112111111111111111121-12112111212122211132112112223211233311111111111111111211111111111111111111111111111111112122211122121211111121211111213111211111112111121211112112121111111211115222112421224111222312233323441211111111111111111111111211211211121221122113135212312212231-11311-1-11112111212222222222-2222223222232222222111111112122222222222222121222221-111111111111--211111111212-211111111211111111111121111111112121221221111311111111113122112122112111131211111111111311111111111111113111111-111111111111112111111111111111211 4358gnN-XAG5LJQRMNKNONOMOJMNNNOMOONPKPNPNNOLIIMLSPOMSRcSMLPKPQJEGHEF6FIHIHGAC5CDEIHJHIOKLIUJMPOSLHJL9GGKGD8cbg*fpfjlqaVTWbiW**Q*S***9*v*ZUWaqQcqQVfaXNpSUzNibcdSmhVicjKgOGhLpbfCGML*HLLR9TafkNVS9IJWLN8 ----------------------------------1-----------------------------------------------------------------------------1-----------------------------------------------1---------1---- * c.15.1 BRCT domain
[ 209] --2111----------1------21--123--211111111111422233233156434641223133 14129114335112B9978-79--AE767778BDDDIEXS45272114-11-846332--9542575B7521222111213212222123333333---432363153122222222222222333445344524---1-222213213221111111111112122221111111111111--1--222-26333333432343334434445333133442311111123222222222222222322242--1--11---------11---11111111---21122222222221-------------211111111-23158555655685823334665252412223322543222344431221126433------4696D31475576223323313321A8A78E7C142-422121643367A7---237211224944444444511242211111111111----11--1------1-11-218324A77C956A6A6566699BF6666-9G8IDHIH2297778253C684DF2846735524565555231BD513334436334444153432353444547633-------------1---------1-5587859484878877764787886779B69B2-1341621122255564567665755577-6778755767657667667AAA675677677677677677776766666663168888888888822241111145554569A224323111111111CECDE77355B5DDDDDCABCFGEEA787311111111269986666678788557787734422222132442222--------211------------------1------42332222225312 33239A9-YFH477JSRTHSUULXdXMGGIGFEFJGHCCB8FCFHGMJQTggjjTaTMKMLOICC9BC6FBABBDCF7BGBKNLFT8DAHRLRCIAFBD98BFJCI28dLRCJ8BEJBBDAEEAQICLFl*G-OIM7FDAIGDE8AFFB6HC9bEEBDF6HX7GBN9GCDO9DBCBDDA*CBBDHQQjmRYNJEWNPTI ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
[ 210] 44434375887887874577765443332433425335667775334325446277577774564-22 79C5C34444453486777-7644AB7677779ABA8AJG8AAC57866553EAC66844BBD799FCEA64333333655784645488785666233666869666844444445445555445365646586ABB874455646464374344222323453666754322442432236657755464677777677578777789667677679A65747888777755555555555555556665422-22-41-3562221151232554343223313343344343545222222222222232222233347CA9C66666666677966433365833955754465787A7A97A795576586684444488EAB657AACBC77776676679-76B77C677943866466B976A97D66698988AB789888888888994498933333333331122222222222223333569L7498768DCCBCCC888999CF99996BB8F9ED8456679856678ADC8449653346333333334598949C897764676665DBDABCFBBA9CA558B44454333444334434333455556676B554666467866666766657667598413784543244486866765667577755-65555765556755555579BA75664876777777777777764455555446656666566663445666556666636555555544333344447777745444A47777686A676765867444444444355575555566677886666666644443374444455--------43211112-2-2333222222322211177665686766755 55-1956-F56335656767795898B5544445548445455444777978EA7866677764534224444644515544434453488666697676543A8926B6DAF98796556885GE4B5R*A3CAM5644957B538766973E5677A6CN5A763N95Y469666A6*66677HBOJ6EE68C8776 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.48.1 TK C-terminal domain-like
[ 211] ------------------------1------------------------------------------- --------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-------------------------------------------------------------------------- 5323XWC-I54-C9M78IEGGJEFEDHFH8CBB8AA9DABADEDDDDFBBECND8ADEDC9A6A646625A47AA56-45588678344BpL8EPD96869A4BNB-8I5********x*gy****x*****O***u**q*****Y**vk**U*w****OXYUoZNn*l*iS*Z82947G43358R*q*H*G24DDDD3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.8.1 TRAF domain-like
[ 212] ---------------------1---------------------1--1---111----1---------- 111--------------------------------------------------------------------------------------------------11-121--11111111111111-111111111-1--------1----------------11------1--------------------1---111111111111111------111-------------2------------------------------------------------------------------------------------------------------------------------2-----1--------------2-1-----------21111111112--------------1------2----------------112---------1---------------------------------------------1-----111111111111111111231111111231111111122211111112121-----------------------1-------11--------1------321--------------------------1--------------------111--------------1----------------------------------------------------1---------------------------------------1-----1111-1---------------------------------------------------------------------1-11111111111111----113333-----------------------------------------------1-- A758RNK2*Wc7FESJJMMHEHFCIBGFFCFBEFEDJFDFFEEDDFLNIIJJMKGLQSIKKKC9CBAA58BAACBDC7BCB99B9ACCDGZLJUbYHFIDEJEPRQ1V*F*ttx**wmcaXfqi**Z*b***E*u*YdhfyamzgSlaXZsbP*itteoQdYYeVVPefaXRgdJ8wlu*chaYfmhm*Nv*v***p*c --------------------------------------------------------------------------------------------------------------------------------------------------------------------------21-2- * b.85.7 SET domain
[ 213] 22222432222222432243467312223432113343222223425333434244364421116232 2132463322233311222-21112322222233332112221232143321231111113233434234235554446264314424556625222--2613231231211111131211113222323323443334232326423-212453311121122331235111122211132134333244313344433444443353333134342312233555565353333333333333333461232245534251553355352333444555666756665455555655666666666676656644466663A669665667686758559774A554334323885B6244433222335244211411111323245433A33644444444443-553572323361544455445534433247374344334111111113231336822121221311111111111111111111111215234264334332555555456666462847578229773458544672353234345422222222113254A7474685567643241442342222243424333211111221111112133343338664514221536555556354545565741-3341311-22297677979CBA9DDB9A-8999AAC9C99BAAA9AAA8B97774898A8A8A988899888898A999833755655566555121323232222262322667566556656555111111211232455432522222262431111111111677755555897772321111223121211123322541111--1-31311121---11-12111112111---31322334332352 B93588K-mGLBJGG47758768BA6A8896566663BC9DDD688C646796A67988766866585254466675494646496B449BA7B5B655B585B9A66JL*GNKLLYHIIJINMVSGdJ**T8bKsINGETLNTGFLNJHdGEdJRHPOV**NNTMGQJK*BHXN4NUI*869C9SFISCJMBHWURWV ---3-1-1--------1--2-1-11----------34315--------2-1---------------------------------------1-----1-----------------1-----------2-----------1---------------------3---2-----1111- * c.7.1 PFL-like glycyl radical enzymes
[ 214] 33335343344433448343434564455955657457455546559457468634333333332634 5762334444433345444-463356444444655593633336333433433633233347445436444444433333543444554453254433437563555363433434443555553434B3454333447522654585545544675544555446657665565554564443334343332333334221223522332232222222432423422222234332222244323243235322222332222223332223232233322322223335222233322222222223222222232222223439A9BE967A82598D544273353242242234223233226595736454433234549544364533422222223222354245245643333334453445543343343346433322222222423254532232222243332333333423332545526453334444444435734445544454433433474333336547435544344464343433333333343643434434333545453232551754633585447-1415654356545656464454734554238333325546534444334333347334335434333343534464544453443-44444443344454444435435433444445645545565444444554434333333333343335333334434644734343333433333433554354343443333343343643434344222222123653534444553964D343444333434336A4444456665565433322233-36973427736572439A443588636653534 **FNRUB7hAC9DEC9CHEADFDFBEHDDBHFICD9B8C8AB999BC7BHCABD8BBC8AFB8CB6A71AB9CA9C95B89CB98D789CH9CGGL9C897OBC9K7GMKdISROOO98B97B7JKCI9q*D1IFG8A88E7AJD9CCA9G98GCMBBG9PiTIZcQD7AjFKQGABFA*BABGE*TLiIRW9CMKKHD ----------------1----4-------------------1--------------------------------------------------------------------------------------------------------------------------------722-- * e.29.1 beta and beta-prime subunits of DNA dependent RNA-polymerase
[ 215] 11-1----1-----11--1-1-----1--2141---1---------1---43-----2---------- --5-1----------------1--1------------2-1-519--------------------3-4-531-------------------11--------3-1112-1--------------------1---14134438---31TBE7676-----------52AJHKA------------11112----------------------------------1-------------------------------------------------------------------------------------------------------------------------------------11--------1----1---5---1-----15512---12-12------------63234243322-1-----3-111--1----12-1---121111111121112-11--1------------------1--------2151------1111124111111-21111-1-13221---11-17----31-32--5-211-------------6211-1------------2--1---111114C-----------------------11111121-1--2-12-1----1--1-1-1-----2--------------1----------------------------------------1-----------------------------------------------------1-1-2----1-------------------1--1111-2--222223----------------1------11----1---1-------------------------2-----------------------------1--1--1113-1 A969OTe1dIOEWOXDGKGKPRMONTQMMMMMNOJMOFGGFEGLKIJMOXNGJJFKGLFLKJLE8JKH7HKCGGFEFAHGAGHHEGORQHPQGOUYNCJFCEAQOLAYGb*r*k*r*aTfXWsc**N*U***C*v*QaST*Yo*hVuYVN*TR*XyplvTs*UtkZFsXivRWkoFWXM*HKLHMjDKiJSbACNdPPP --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * b.70.1 Quinoprotein alcohol dehydrogenase-like
[ 216] 22313221232322242311311216522122222112222233213222331111112232224123 1493B522222333B7866-6A118B666667999987CD297564344454855545339AA4A8C9AE52111122-4A524234333232267---24354256312222222-1111111321123133436669611246655645432442-111122334715-22-1-22-1--13211--2223444447853456875974434568121452245553333144444444544445543324-4122131-1221112434-12312111111121-231222222222222222222122122---2222-5132666667616334551322111224221-3311-22-21555-12152477762111165736342342363343333334B-44322423465164467774566634643434342343932333333333132341111111122--1122111111111211114443233334656674444435547555524A485976-1333312124362333312222751------222214342-14543495453446235544434495232533222222413111111124221326457412456175454445444444444731-2333321-11134441352334254532-33232243433533323344464365133233333343333338333112321644444344444222522222566643966-----1-1--1---187877621424279A7C9A7859768778-3421321313325666663556444423322222222--122223223332313222--1121--23122112223342111---411111--2533 5324A9P1S97867C97F6CACACCCB87A7778A4A878767676537EB9HIC7CB4A797446333544555653456235685734A4777D6566697B9B1ANB*RQYVd*NHOMOjO**MfP**b1iUqJTJLcNNbQFQSJCVNJ*GQGm*AOHITL8EL88JECdECMJB*EKCVGHEGN4CCBFCAA9P ------------------------------1--1-----------------------------------------------------------------------------------------------------------------------------------------1--- * d.126.1 Pentein
[ 217] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------W****rOY********F************r**UT****PB1A*---------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.212.1 KRAB domain (Kruppel-associated box)
[ 218] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1111111-1----------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 561189Y-YCC2A9F8DEA8B9BDB99AA9BABB9B9DAD9DDCABCBCBDCHBDCHAACC986788829998AA99588989779BCEBDDDMEDDAA8D8DEIQ1W*F******usimlq*o**a*f***P***khYu*iy*tk*lxo*le*q*txmXniRWVTSyXdwOfTM2ILLSHIF9CREOF9KFXcs***x ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.72.1 WW domain
[ 219] --2--------------1------------1--------21--------------------------- ---------------------------1------------------------------------1--------------------1--1-1--------------1--1--------------1-----------111---------------------------------------------------------------1-------------------1---------------------------------------------------1-------1122-22-----------1111111-11111-----------------------------1---------1---------------1-------------------11------------------------------------1---1-----------------------------------------------1----------1--------------------------------------------------------------------------------------------------1----------1-------------1----------------------1---------1-------------1---------------------------------------------------------------------1----------------------------------------------------------------------------------------------------1--------1-1-----------------11-------------------1---1-------------------------1---- 1---omJ-411-KGK657B797877788758877765766566887666876A588697767866667447243676476535455A98EPF5LIKIGJFCEFYaY2Y6Wz*********v*****x*****P***r**w****vm**um*wl******QeppgXUP*WY*LocS1-1-7-111-1-2-7112124753 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.87.1 DBL homology domain (DH-domain)
[ 220] 11112154555555431211221352235244222234333332422223222-2233412222--33 5565D65744476597777-783388777777799979EE39763563355485766544675298A675745544332333754366554424111--34455554441111111111111115426643247456688212555335333334445454544353634443445444444444332224564544544464444456477564454445544333333564444444444444444444442123324-4-4422333333525443333233323343232333333232333433422222333333312334333333333343333222341124312422334322321112122445877833333579776649898866666666667-446446656783977B77A88B7776556767777767854555555645445794435444423--111111121211244434676637A9776666776787766678888578889CC934664766569788AB3376557854444444335869645224753456672556564654777799224323433333323222222135352447665643645476666797677686676774-42447-1111167885565554555555-55555555555555555545657766766666666666666667555555554555555555555115533333555557756554544233333444AA99A7644565AABA698AB67776988455455545535536666658465556555555533333341553355--------3-2---------------1----1----2-111111213322 534499A1LA62879AC8CDCB8ABBB89A9A98757878A88AAA7A7BACGB789B888A8579794796865994796677856688D8CB9A798999DEGA1De6FBEFNEJCCAAE98FIAM6d*J-KCQ7GBCBDFEBDAAB9GADD9LA9EDTc7H9B9J87bKAFB9EJB*AACGDHA8R8KJHEA899K ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.84.2 Rudiment single hybrid motif
[ 221] -----------------------------1--1----------------------------1------ --------------------------------------------------------------1----1-----------------1--------------1-2-----1---------------------------------------------------------------------------------------------11--------------1--------------------------------------------------------------------------------------------------------------------------------1--------------------------1------------------------------------------------------------------1-1111----------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------1---------------------------------------------------------------------------------------------------- 5212FJI-B4-1A8E64863644534334363746586365562445455A8AB876737643334332557222221343223637599894CB79477256DEN1i63p*******yvl*****v*****H***rt***p**xd**up*km******P**icWqP*bfzh*gQ3353C321137CE*5*B3378BC3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.49.1 Cysteine-rich domain
[ 222] 11111111111111111111121111111111211-11222221112111113111111111111111 2222222222222222222-22222222222222222273222222222222323222222222222223222222222222222222332222222111222222222222222222222222222222222222222222232H3433332233222222331233542222222222222221122222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222-22112222222222222222222222233333333332-2222422222221222222222222222222222222222222222222222222222222222222221222222222222222222222222222232222222222222222222222222222222222222222222232222212222222222222222222242222222322222222222222222222222221222122222212222222222222222222222222222222222212222222222211222222222222222-22222222222222222222222222211222222222222222222222222222222222222222222222222222222222222222222222111211122122222222222222222222222222222222222222222222322222222222222222223222223222222222221-221222122221212222221222212222222 1112C8A1B581A8ABC596679A8A787A9AA58756768688779889B98888A889895575554587665754555558767566C7CDCH85874559B916FB**uoxqwYXdceub**V*Z***1***cXba*UetfZeaVRnZQ*UynioHRYVWVmKvSUfHRY935A5i855A8QXhw7fP3447984 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------21--- * d.50.1 dsRNA-binding domain-like
[ 223] 1132214333333335-534222244433333222322322223232234562212112224452-33 5474755677744444555-543347555554445546BC3433657444458886451186B694AA6532455444213373323255482634-1269664754751-1-11-2111111122243332233444342227433633344333363333333565533333333433337553323124599A9AABA89AACCA855555B9944564344333358544444444444444444434122344323225633542425322222232122433222112211312222332232222333432333353186555544432332556332344335422344533156345553342634555644335559543335634466676665656-66756A46IB44B9999B9CBBA98C55456865595664444444465553345222333332211111111121222142243356434443697777A66666667A9AB9987BB5B7A247663575586D76945332336356444444336448365534626655634334356555545885A44A5355664534434333333233346664444568477877476644677756893-3334322122284876666565654576-66869576566565565566978777755555565555555557665665543766666666666223634332766644846444544444444444778884636693BBBBABAA58A775A98444343434365575555556767665766665533332242663333-11111116-1----1---1-1-----1111-1---53343453334527 2244AA5-D464ED94DB8FBGBHHFD9777767989DACA986669A889BBH99888697349555456494565557664867667AM8DA9E65545DA9BB-6FCSGJBBGK9CF8889DA9J7Z*H2KFS85DCF6BED496A8CC6F9IB8FCE7AKDEDD8ADCIE954ED*C6EE9XGJQ8HBA5DDBBQ -------1-------------------------------1----------------1-----------------------------------------------------------------------------------------------------1--------1------- * a.127.1 L-aspartase-like
[ 224] 11111211111152111-----1274466685544111322322121213333A111-111-1-2111 7754956666656565444-4733674544466777777A48794533533378754422876575779973222333344452545A884547337--7866377868444444444444447877676655478557D554A3C87A66546443222246738987622351114153244555452677888888888888888886567888789775767776687655555555555555555566266669533455557665556366655554555555555555566554555555555555AA5559886388B78888888879B766665667E4677686777777CB936777754749A56644555568776445665644664464666-ADACB997864357776677685665865587888758677777777797446543333344433DY43664444444443343375455676768AADA866666AA87888867877687747A88786566895758776663566665556766667387746784948774879777759645666676465444444334343433353545878667775677767776757555766567662-57687-1111167679787777777777-77777777787787777767777767577777877877676775876777951777777777777216555555777786775656666766656665777776666676776779AA9898899AA3333343335655666666B55666587677777777723734433443333333345522124-463243312243334444485857565464823 2222343-832-24523334334444333433334343332334333454654344353452323222121342241-22223332333222333222222233323445F9E8CA885679A6DB6E6J*93C9F5877G69A548657966B755973746B8D2837O64864225h75643A34A37444A6543 --------------------------------------------------------------------------------1----------------------------------------------------1--------------------------1---------1---- * a.60.2 RuvA domain 2-like
[ 225] -------------------------------------------------------------------- ---------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------ 488C114-5--------------------------------------------------------------------------------------------------2--**********y*****x*z***K***s*w**y***b*xrd*wd*y**********LIeHP*d**A---311311-------2------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.60.1 TSP-1 type 1 repeat
[ 226] ------------------------1--1----1---1-----------------1------------- ---1---1--------------------------111-------1-1-----------------2-2--------------11-----111-----1-------1--------------1111-----1----------------11-------------------------------------------------------1------------1-----------------------------------------------------------------------------------------------------------11-1-----------------------------------------------1-----------1------11-----------------------1-----------------------1-----11111111-1---------1------5------------------------------------------1----------1-----1--------1---1---------------1--------11---------1--------1--------------------------------------1--------1----------------------1--------------------1-1--------------1-------1----------------------------------------------------------------------------1-----------1------111-111--1-1------------------------------------------11----------------------------------------------11------ 3911*uT-B45-MJS66D9DDB9EDBEBB89999988B89B9A999ACBBEFGI9EED8BB9756766366546756565766664666CHC6EDE9979898BBF1ggl*******uloVqzl**c*q***4***Xson*ov*oTuomh*kR*w*qs*U**YijZX*atkLM*Z38A6*43445KcvmChE97EEIGE ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.109.1 Actin depolymerizing proteins
[ 227] -------------------------------------------------------------------- ---------------------------------------------------------------------------1-1----------------------------2-----------------------------------------1------------------------------------------------------------------------------------------------------------1-----------1------------------------------------------------------------------1-------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------- 77ACFFR-O888CCPBBCC9BBAAA8BDDDEADECDCDDDBCDAABCDCCDDDF9CCDDDDDDECBBC6CDCACCDFDFFBCCCBCFFFGLMBGHGFFGFDEGQMS6KY7m******noijlrj**k*j***A***fnng*gt*Wdsqgh*hb*kynnlTZxfXTfPpQTlkbRN9GA9tEFCDHMHOcDZBKIEQQMN ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.29.2 Bromodomain
[ 228] --------111-111-11121--11--2---2-----------------11--1-----1---1---- 22112------------11-1-----11111------11-----------11----1----1-1--1-----------------2---33---------1121221212--------------1----1---1--2111------423222421--1----11-112222------------------1----------1------1-----------------------------------------1--1---------------------------------1-------------1-11111-1---------------1------1-11----------1-----1----1111--1--1---------24225-----133222222222211111222223-112114-2121-22232222222111222211111122111111111-1233-111111111111--111111111111211-1-31131-------------1------211111-11--1-----1121312112221212222---------11-122-2123--1-11----112---12---1-1-1-1----------------1--1------2413452232132112554333-5-53-44--13124-------1-1--------------------------------------21---------------------------1--------------211-11222223322---------------------1---3767764453644447444---1-11--254533333344433-2--------------2-2211----------4------------------1------------------31-2 DF87FB4-I223**CLQPGMAAAIGFC77A879BBA8787787656caITOPOSJJQTIKPNfKBB666DE6HBAMA6FDCGGERI955**kQLXkCBBMG*DSf*-6I5JOLMB9ODCGJSKEUOAaFu*T3TFb7DECYFG*UCEBH9VB7*FOGGQBG8YGHsQE126bSFC48b4a7645D****L*mAC****7 ------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------ * b.50.1 Acid proteases
[ 229] -----------111-121-----1111112112232--433323321121211-11111111--1-24 22B2642433332344434-33333633333336665798343234221452654234--4332445454311111114231---1--2222-511---2334412223--------------1111112112323332211131522533233334333333325224533343333343344411---312555555554555555532222556234442233333346244444444444444443545411331232346114421223244422233333232222222222223333333333332442223333-41153333333433242212222112132141111111-111211-132514766522222355353335553522222222222-55355454224-8447554774225544333433333434244444422222432--------11-------------------3346323322334455344444444544443345435432233422322442445223332332223333354323312322132212222222212222233235424211112222211111111112421211224435635535444433444444444446--21112------34582353333333233-3333333333333333333344653333333333333333333433333332-324233323333---3-----222223223111213122221222445442321235555534465444437861---1111-44444333334443322322222221111211322333311111111112-----------------1------------11111-421 BC77CDG-iHP3EEGCCDCBCCCDDEBBCAA9A9A89BAABAABBABAACBCCCBCBAACABCAC8796779B7AAA79A977878A99FOECEEDDEECCE9EEH2B*LlPOLKQPFEOIHIFYbH*I**i1UVzPGFGNEIPIEJEHKMIISELHGLKSTIFIHJMDIVJMIF7UTT*NOOLKeNctDXOSUOKLKl -----------------------------------------1--------------------------------------------------------------------------------------------------------------------------------1---- * b.62.1 Cyclophilin-like
[ 230] --1---1---------2-1-1--1322--1322132-11--1-4613542436----1-11111---- 2112--2322431-13344-462292444444B4654645-24414112112234-23--3223214123232221222-2-2111123332-311---2221212131-111111--------211233122-212233---342B645652222------4613C631------------11133112311333333632323432211111333121311364444432-22121111122211--11-75315611527331163211331445222111122211111111111111111111111121122211123-235444447455528665352823113--133431323--133632111225221-----333272-53343111111111113-34224635334-2111313314255723-2-254341--2222222231--1221-------------------------------31--3111-2332221333322234444244233535-13432233344242152521214412-----11332421321-22231224-22242532324412552---1-1-11---211---1-1-11167344-21-11-212---1111--2-1--11----2427------31222423333333333-333333332333233333246422111333233333323332333322223--433333333333---1-----22316-51------1---------2222223-1242333434332233222321121-11-12---1---1-11---1111211111------1222--22----------344231-2121111111-42111221112---2---2-32 68A9JJC-XCB5MMNEGHDFIGFJLHKCCBBBBFIJCFEFDDDEDDIDIKJLPRGFIJHFGGBBCCCB1CC7DBDCF3EFBDDCBECCD9IFGEDHCCBBAGFWTS3IGVNcjTodaLRPJQQTtgMsR**iC*X*KNTLYRQkPARQLKfLP*UcNRbDU*PCCJCnFJtLbGA9GBD*977AASOTyFZPCDUgYaE ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.220.1 Metal cation-transporting ATPase, ATP-binding domain N
[ 231] --1-11-----------------1----1----11----1----------------------1----- 1-1-----------------------------------------------------------------------------------12-------1-11-----1--11-----------------------------------------------------1-----------------------------11111111111111111---11111-----1-1111-11-1--------------1-------1--1-1----1111111111----------1--11111111111-------------1------------1-------------221----------1---------------------1---------------1------------------1111-1---------------------1--------------------------1------------------------------------------------------------------1------1-----------1--------------------1---1-----111--111-11--------1--------------1--------------------11--------------1----1-----------------1-------------------------------------------------------------------1------------1--------------------------------111111---------------------------------------------------1--111------------21----------1-------1---1---------------1--1-1-1--1- 1112573-----1--2-112---1121-----1-------1---11----1---11--1111---1------1----1------1-1--1-1--1-11-1--1--2-924*********y******v*****5***s********l***o*zk******Y**UmbTGiLHcMMYW-411A----1333615-13-122- -------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.17.1 Cystine-knot cytokines
[ 232] 111---53655567513-2-22131---222113----32133-11131--21-23355331232--- 3562743455634-MGHBB-BO55VEBBABAEJNONLKdP491552112112437437--85F3A5JCF65244421153C531211112423511---36-114265212111121121111295667578426111443333-654434533443221331521316454444545443445622--11151111121111112111433351122322423644554772444344334444443663343133321423-144212242324541112-11-221--11--1-212111222211221-331112331147A89999ADB8C943BB24449231116354E995A3171A4452411324A9A91121138E9823386559444444554471337247444AB-6877657445BA223B4445324343488888888444354313312311122--11--311111111221134ED2235842868B999544666A6466614G8E4B46134286B83253443522423243311223222116211BD5654534A764-4552625733454583711-2-31122-------1-1332-311334323724432433424432233264576--12343------21313344335434432-33437353343444344421332-21-1-1213122112222153433333--211221122122--1222232222138-22111312---1--1--884683532223763626575633255363111222112557444444546443155645223----2262661-33111-11-1214--------11-2----16-------233133-3313511 3211966-934155AXRVJTEKKoNlc9B9AABA99EGFCDEDEBAFLGNOh*sKIJGNAADE7B3871642D7A511339987B5855HWGR9GAEDE995CG4A-3d7tEFCAFJBCBCBJFZMDS9W*H1KFFAC7ALAAIDCA797F99NC96EGEJS9J986A8BHGDGD5B82z45587CDDMKMD788659A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.4.1 Nucleotide-binding domain
[ 233] 21--1-1--------11-------3111223178511111111--111-21116-----1-1111--- 7667666656667675455-56667555555667776677677965575666666675666656666789676666666556665566667658774--67876778674444444445444466766777766777799222BA798799869666676778878C98756555556555596666786957567685776787556656666766555B766555565657666666666666667888766676678676778867766886666666756677777777777777777777777777777777777767A9887777777878767768875788575776A976776A668888766554555755555655565565566655555555555-65555655755565555556655556566558665555666666666566666556511111133556655666666666545556766588788666666666666666666656666888868886998889898A899866666866766669B8678787675556556555576564578666687695555555555655555555556655667666668876677777679666786998875-5766625-54566766677887776677-8977877777878777776666666666665666666666656676977776566666666666655565555567676668577768677775666766666676666677676666677666667A9A98999977777767666676666666667666676556677778944454444551--1-1---1--------1-------5855566556686A 11--222-61212223422244655444453335343444343342753343744444432223225322422343323333432322233242352423433223-2445523276221113131262BN3-5351312213421221252132422448635531322765541457m64544B66D2BF2253451 --------------------------------------------------------------------------------------------------------------2---------------------------------------------------1------------ * c.72.2 MurD-like peptide ligases, catalytic domain
[ 234] ---------------------------------------------------1---------------- 731A7---111----3322-2A221122222-54442532ADAJj----1--558-----862-93C5543----1----A168AG87---1---------------11--------------------------33333---34WLFECC11-99---3--8E5-77B3------------B-41----882777775672777777122233777564B2EC33333376---------------------233--5----5522-1-14111-----------------------------------------------4554A33322325361J774343511--3775176521---211113---6237AA51111124RII868IFEGL44554553546-NKIII8FO8I51GFFGLNJMNNEEE7BC82A27A55782--------DAA5-R8K--------11111111111111111-----8A873A9932EBCCEEC8786DDPTBBBB88EIU9GCO--IIEOCLCDN14U55GHLKIQWPI-------98ENTV147346AB5BABAE-878H793FC111121-2B6641-1-------------GEGMD53NH9TPKVKUObTUTTWQUMSSSRNULKPNQ--1CLCQ------JLC67JAHGGHHHJIHF-DHGIHFEHGHEHHEFGGHGKLFBB---EDDGFHGFEFEGFFGHAB9788CB2-B66666645666---F-1-1-CEEEC3dBN---------------456551412-BPLMPKLUMOOLLKLHLNN-----2---NCKIHMLLMLSUPXWDDEEFEECCF3333--J-AA6489111111112-4-------------------------1-111-1------- ----21-----------1------------------1-------11----1-1--1-------1-------------------------1----22------------1-------------------------------------11----------1111-4-1-----1-A1----------1--B1----6---2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.1.33 EAL domain-like
[ 235] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- TGEIHGG-*OJ7EAPA9C9DBDFEAACDDCEEFC996A9A7ABDEFFEEFGBGD6CGBACBECECA7C48BA9A8AB7BB89A7A7AABHIK9LLSKGLF84EKTO6PlBl******nccdjxi**Y*e***G***ShVT*Vp*oSooWVtRM*jvtxxGPJUaYLGiKLcW*UD7LQF*JJHYJ****C*pIHVWZZF --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * g.66.1 CCCH zinc finger
[ 236] 44344566766787673567676A72272355546549565566745675555843333334434156 46B5731344323359A55-56555955555586566495344636243313457366--558366B55332222222117744312122322368---4544463323---------------43333434352433771118623543332411211212344475431211111111112324411235355556355465434422553446444623122222223313333333334433322232122222211225511431121223111112---11-----1-----111-1111111111111111111-16449CCCBBAD5A5384453323616231333E93694126432411413463445111116688822345755333233333321445448587631922444C656546743332333334436666666635633554-----111----1111-11111111----4367335652676787856665778C6667569BF5FA72456685466674465346-1133322222222125864CD352-4852111-B7B4D56446676695B-1--1111112221111111--22121542344734224334334555744574484--11331------64534535555566644-4555555555455555554556563547776677776768667544354542-433333333333---23333333333457711134213233121233343343358376766755454475877----------43345455444344333232233311111-233333431-------5-2-1----1--11--111----1----243222422235-4 6544BA8-H679A78EFB8EDEBEGEIBCCCCCBCDCCCBCBBAEDDEEDDIFOFEFCBDDDB8798B59AB9ACCB9ABABBCBB577AIAFECB78889A89892BXNWXTNQGNCDDDDFEaNBSCs*N-THZCDFDICFKCAFDDDHC7WFFFFKCGLAOEECEB7FCALB7898j554A6I8GGDB9DIC9B96 -------------------1--------------------------------------------------------------------------------------------------------------------------------------------1-------------- * c.31.1 DHS-like NAD/FAD-binding domain
[ 237] -----------------------1-----------------------21------------------- ----2----------------1---1------1121--1--1----------1----1-----11--13-11-----1----------221--1------------1-------------------2---------11-1---2-1-1111-1--------11--1-2-3---1-----11-2-1111---------------------11--1--------------------------------------22-1211-121----22---11-------1---1------1---------------11--211---111-----1---1-1---------11---------------------1----11-131---1-----------1----11111111-11-1---1----1-------1---------------1-------------------2-1-----------1---------1--1----------1-----------111111--111111--1121--111112-----1------1----2-------1--11--2--11---------------1-1----11---1--1111111-1--------1-1---1-1-11-----1----11-1----1----------1-------1-11-1-111111111--1112111111111111111---21---1121111111111112-11111112--11111111111---------1111--1-2-------------------------11----1--1-111--1----1--------11111-11111--11--------------2---1111-----1-1---------------------------1------------1- -5-113a-923273C83989567555A775516855545557566476455554656225453-3-41-31-1312321222372-573577325E79962742261-63*******yWdju*w**d*j***F***bqoq*e**nZ*xnh*SU*d****KTeMqtNFuOI*C9o93141311-55C66A8G71567541 ---------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------- * b.121.5 ssDNA viruses
[ 238] 33-1--2333334544122222-4I55545D7323--3322232532224766113--233112---- 2132224467643332255-581172555555655852762228533442225232431133625253622-------33336151113421-4-2111282A67A534--------------2323321-232-544552223644873333323222211342369531111111111115E5552--76444434484444944464444444568544333223225434445443444444437448411111121-11111114111113335222111422-----------222222222222223322233344AC6B8888888585548755545-53555532F86724464573372334335119-----4411761C418115566466366D-6643C894D38-177732A6226928232B2654553333333333333342424-----------------------------1-21324444667768545666B96356662677E475I25AE4473IFBC8654B7E67435533455445D6657335333353455562365244327332266444443322222244443444425131585735B43722444333362933E2322B22---462C------23444343333333333-3333333313333333333435444445353575555575335533333332-444444444444---81111-222374333333444-24561--36456744455A758BG555666669A4441----1---24546444446534452--3---------1253553322-11-----216---------1--------1---11144422333333613 ---1B85-732279968BBABABFBDBBB6A8ABA9CB8B9BABAA7A9ACBCDAAA9A9888785652742778453357775772226A98374322433469F-7J4JTIFLER8ABDCD9SaDQ7z*S-pYs8FAAG8HLFDHA8DNC4*CcODI8Ir5D663667R5B8J2A7Bz537A9**t*C*j64IQKHE ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.17 HMA, heavy metal-associated domain
[ 239] 22222334333333332333443245545262322322343324434332434445443452323132 3583944555545369944-47336A44444687775676442443544445867439226553748898322222222243524222656516332--2534353533222222222222224332232223334554422254355444334223232223425445522222222232254333333334777777774777777654454778456574433333396333333333333333333334344344333333334423234344422332333333333333333333333333333333333333333243266667687464473355553232243433A945233344333233272322242222222543332324324455455455A-333332448G32AAA6668897874233339A55556772222222232232232222222332222222222222222222225335423333377788854444885976775688A25342233223222433346242232263222222222232345435464235333354634354465657343221222222222222222222222222334635667455333354664436365357112322211111153543844444444444-44444444444454444446643344534333333333333335444333332656566545666111422222333322785333222222213222544463322222556557544877625442222222223222222222333224555555444333322243322332222222222212222-222222222222222222224322252222322 7666AAB-hA96AAEDDCBEEEADGCEEEBCBDBBACCABADDECCBCBCEDFIABBBC9899AB8787A87AAA887899AAAAB799CJBDADECACABF8GFI4APIbHFGGFGA9ACABBIG9N9Q*A1EDKAB9BG9AGCBAAB9C76PCABADALMDCAGBGFGNCFIEABFB*B9C9AYFLUCKN8BHDHED ----------1-------------------1--------------------------------------------------------------------------------------------------------------------------------------------1--- * d.127.1 Creatinase/aminopeptidase
[ 240] 222-1-2-11111---2111111263311323335213433327524644797--1--1212322--- 5112112666743222388-8D22F5888887D86B557523364325611143D235--44523183642133323342534232143333-311---1213-4313311111111111111-2323321321234455---372DB867544221111115522C972111----1----14222112432555555754555665241122556462331564444434133242212233322-2112A9348A4374A66337745433378A3222211533333333333331111111111111533555333223246555769686748774352A332342224644332232244633122329226-----64449716637431111-111117-5942A946845-4334327612367D231A1554562223333333344211434------------------------------2614-543332222222333344344444345572667-19A3423CA77165364C341254--11---25533941332133152546-323545456344248732121221221----1-------1-28A323341-32121111122231132111521---3539------42422413333333432-3333333324333333331565222-15353555555435334322222221-422222222222--131111-34659231-111-1--11111--1322433333163445666563467463451111-11-14-111222221--333311211111------1232--33--------1-425332-2221211111-22111111--2--121115242 3445BAB-N873DCG9CDDHGGCHHJFDDBBAAEEFBC9C9BBCDDECEHKNPSDFIEFCDC747686-68466889357778778A88AKBCA8G99968AEQMR2DGHCVbNXVZFDDBIJFejFZF**a4mOwAFBFOCJPI9JFIDQE9fFPGLR9KoL97I7cABYLS895FF6*8879ANNNpFWMCDPcPUI ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.82.7 Calcium ATPase, transduction domain A
[ 241] 44114-21-1--------1212--111-12-1--111--11--11-----311-----1-12-1---2 3332422233323343422-223332222223232323322232224222222232332234322233444222223333323222323333221232235243423233444544222334431143322225233334223334342456112222247322333254233222232222321343322331323322323432623233363342643245222233332323333233333243543432322234222335533232232454122234322433333333333222232222222233222322235345222234324353434342333323223323334223434223532223243322224323644634553343333333423213222232233423332235632742433323222224424444444422222242224332222224222223222232212243223225333254433412222223222223255422332334423322331122222223222332222233373236653223354446354564456643347744324534344322333343243522321443354345244443443255433235334122622212222243354223544434434-44346444444443434443233354434332332222333332434342342334444434444223312122656722453444343321222333333534522424564535523323422322232222225224224434343551243334232234322333333443332322222323321-161-12111111211111133233343523543 55129B8-LE97B9E89DD6B88765BAA89A7C784867966CAEB7CB88EG89BA989867986542897C5698576A98456469B69E6447571G989F2AHLUgaWhrSEJMLGPLufEpH**n8*g*KLKFYJKTWGPDEKbCD*JUOUQCLTBDJ9BXFNJCLD97GA7d86667*EEI7SU8A9DCA8 ---------1----1----1-------------------1----------------------------------1--1-------------------------------1--1-------------------------------------------------------------- * e.38.1 Release factor
[ 242] --------1111111-----------------------------1-2--1JO7----11--------2 -2--1---------------------------2111--121--11---------------11--1-1-11------------------6712-3-----12--224211--------------------------14411---6--1------------------4-----------------2---1----1-------------------------1------------1-----------------------------------------------------------------------------------------------2122332-2-2-11-----11--11-----2------------1-1-21--1------------------------------11-11-1---1----------------11-------------------------------------------------------------------22-1---------------11-----1--------------1-----------------------13-------------11-----------69-----------------------------------2-1--------------1-1---1---1-------------------1-------------1-----1---------------1---------------------------------------1-----------2-----------------11111--------------------------------------22222----1--11111----------1221-22---------------------------------------1-------2-- 8832FJN-F73642575876654463744446636577674655465764568B38E7778B421233115232-564662-112433349352474345446KFI-8ZV*******lkskp*u**g*j***L***jjhg*dx*yjunlm*ca*l*z****oi*mMFRFCbFIwH7688T45565*cch7**4EAOCBF ---------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------- * b.68.11 Kelch motif
[ 243] 12----1121222221--1---1133341-322-----1-------131111121111111111--21 3486P455777222FLIMM-MHDDZJKJKKKHJGFGC7F81ZBX1212----132113--YO93u4Z*Ht422222221--12-112-4556335511136545M3443-------1-11111-4-32412221275546111T3386588C7534212111323DKEb61-1-11-----12233333215h23233131422111253115G2219566211111111K41-----------------1---1---------111-2----1----111----12421121212121-----1-------211---1-1--A332------12-2T2881111314--51-2155335-6311545-2423156455-1111F8F9D594A938A33333332333-FEFFJ7FF6931AGGA44778685CI661957678775622222222322138241111---11-1111--2111111111211113521532249FHGINFDFJEDDEAOLPO3UHBG96A923ADB465129789D716635323-11111111126443BA521523-21-11676532K165555rq2311111-----111311--111-1-3112354164-3333645656254445455444--2242-1-1111C2L3152467A4AA764-7435744464759344447CDC4494245333534433343333334334511756456434453111112122655642D44----11-423311115553545-1-IHAA7BBU6A6AD653FFJ4--1-----72224-----224221-3232222111-1--337754451----1-11--111---11-1-11112--11-1---35444122221A35 119Bgq5-F453324BFNBWILRUkZX332566OR99DDDADD344OJFRLJIJEFXUF9A91232311-3-21-55-3324311-121384F4462-1315563441E7SBD99543344445876A5IcB2C8D43539858524681522A7C73D69B3FB9CB79JC9B63533lH276I4327MA315898GH ---------------------1---------------------------------------------------------------------------------------------1---1--------------------------1-----------------------1---- * c.1.19 Cobalamin (vitamin B12)-dependent enzymes
[ 244] 33342554344444433545433367745554223232222223123234544223243324333155 6573E55566554426577-7622C3777775666685434BA934436675543764336533A7LIGJ43222333123262223222222322111253338345311111111212222233434333444655771129496755643333433444554678863444434534333333311486522222222222222322444522254456433333334833332333343333332233312144142-36623332213353333222112111111112111112222222222232133111222232322-11111211132433112214223323386353533242122122636533453333677986557787833333333333-77A877774744444356744333363349446655745555555555555657933322223223322223222222223333444234444465666755677666756999255565555233334444565545444444447465554444546444323333433344323222232223344A92433322222222232222222322234433332323424222222222222222232211354752--11124332232222232222-222223223222222222222222242222222223223232222222222222222222222222223332323344322222322332323222332222222334522222223222222423323333333322224222224222322333333332222226222333311121121122----------2-----------11-21211212224343 4723HN6-L95488BEEDLKGSKUVVP88ECAADHBCA7A7CA985GFGIPKEIBCPJFECC97A8974B8487667588665679756BmNEGIb87B79HAABB35KCLEFECCE86858899DASA**F4MHX88A8F98D99B6A6974C79DG868D8C8HDA98v469A99AA*899D9Orl*C**CDB768B -----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------- * a.128.1 Terpenoid synthases
[ 245] ------------------21111----1-------------------------------1----2-11 -1-1-------1--JAC66-6611GD55555365551-1--1----2---------------1-1------1------1--1--------1--1----------1-------------1---------------11--1----------11------------1---1------111----1-----11----444444244454444-222--44911321-1------44--------------------------------------------------1-1--------------------------------------2113343131113141---221113-1-----231---2-------------1-----------11---1-1------------1-------------------1-1111-----1-----1---11111111------1------------------------------1--1-----------------------------1----1------1-----11-1----11----------------1------------1---1------11---3-----------------------6-1--------------1----------1----1-----------------------------------------------------------1--------------------------1---------------11111------------------------11111------1------1-------------------11--------------------------------------------------------------------1----1-1---1-1----- 4434MFN-J7A6EFMACCC9DEBDACABBAA6ACEBCB9A9ABCCA89DFCBBABCDCCBBBBBCA9A59CEAAAFE8FFA998C8FGGEKFCGGEA99BBBAYXa3WRBW******ebSQd*X**d*d***7*s*TXac*Zp*ZTmaWP*VN*h*lj*Ru*YRKPFyLMgWiKH6EB8*76667SPQaCjH7CbfhgQ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.29.13 Bacillus cereus metalloprotein-like
[ 246] -------------------------------------------------------------------- 434-8--111----4--22-21--15333331--1-1733234472222553AB75CA--1182716886111116311---223856775729661--7JG894FC563333333444444442123342222544474--195112-223331133343112-12241263222261233ABD4411-GAP8888868A8888A888DPPET88ADJIJD29DBBBBC9IC899999799999998777AL1636529111BCCC658D756888A2321111423222222222221111111111111333133333-6LI718A8998837353889222E8H--D54BAFIPBF3Z839CCC6-1-4514552-1111223432111212122222222224-11212212442-466333633355-12-12221311238--------1--1-423------------1-21-1----1-------213-157777A9989877AA78876BBBB699976676-1778445556434644594757A5456666666255348864A533O43333ACB8ED97C6546JFCB122211111111111111111222488CC68877679D99AAAB8688998877977--2D88A---1-1676966989A7877767-9788A8878798888888777C7733777778887888575789758776741877777767878--375645486776985A333636322123224BBCBBDBBBB48989A57659555578781111111114DDGECABCBGA9CB665646645513233-1A55334488898899C6--------------------------22333222224945 ----754-623-26A985BZFNEFJCM542222YgDD74736621159GaAMPMFEBM9F89--1-----------------1--1---B7987433323--38OB-2624685846435136496382FY5-8594125614A6352156248265672-334161I3335I431GM4A755Z4ZJCh6KS-254553 -------1------1--------------------------------------------------------2--1-2---------------------------------------2-----------------222-----------1-------------------------- * d.7.1 LysM domain
[ 247] 55343443444444434555555544455545556555555555557556666666645355436155 4744894455444445544-4444454444447444444445544543444464444422446554444644444454337854444466675633233362677458722222222222222355555555555666774447454447744444454445664644444444444444445555544356777777777576877756997898665565356777667536666666676666766546834244252215644443344437665554444765444444444444344364344434544444444449457555555565644667444764335666455555562675555315665544544444674667646564644444444445-4444446465824554465654566655754444444544444444454444444333334551133323323333233233333544546455565666556666666766666765855555656556555666555575566679456655555555646755564455444364555546666667767525444444332522222225444488BA886675C878A9999899999887897711375554234449877897ADDCACCCAA-DA9ABBDABADBAAB9BBA778777789899989999999999A877888A527777777788872228333333333666567576464555433365555556555756696666666767856661121322167ABD9999999B885557577666555544654444551112121222211111-122121111114221111145544565555553 3111555-5452436643345354735855556333544443355574554575563343333634442344434553644348533335E4474A444435399926C674735832223322B44323I4124612224114212221411632347132235515123449459A7*8A8B8HFNO6IHADFF989 --------------------------------------1----------------------------------------------------------------------------------------------------------------------------1----------- * c.73.1 Carbamate kinase-like
[ 248] 553-54213423424282565431E44B65732-3-136565214265-2845-7A896455321--- 1332F34455711235555-59226F555554ABBC58FH4A6F67533441544242--55A1767A875211142223235-23212222-2----------11141--------------156336-4643343455--18445384436855343333454577631311111311112136733-3325564678735767678422226683335423222222A7422222222222222321114532231-33355112211-3152222222222233444445345332222222222222522111222217424444445434426542333424837432-46412632-31111132111433111111B8NOO426ECCCBGHGHHGGEFGZ-64F44E68Nt21vnnhqkm**vvqK7111EOWPKOTUKG222222226443363B1111111111-------------------5---318JGDBJKLKJLCEEECLLXVGHEE8FMNWBACA12AAAA5B87CBOIFW676251298444444432349722C346D657777A2746324786434466523656322153----------242232275I2623131B38888134666547445441--1225------CDNI8C8ABBCCCCCAA-BAAACCDBBABCB779A7BGIHHK6679A99999999899999F77978793-CGHGHIIGIHHH-1-2-----222272FAS5559A826766733A2222211122G4FEEEIJKLGGKFHAJJJ1111111112566A8888878A9922545444452222--122211112112122122422222-32333223332212441113433433454141- ---1------1--2--------11-------------------1-----1----1111------------------------------------11----------1---4---------11--1--41261-23-1---1-1-21--1-2111----3--112--1-112--1-111-----112--7---------1 -------------------------------------1---------------------------------------------------------------------------------------1------------------------------------------------- * b.40.6 MOP-like
[ 249] --------111111-1--------1--11-1-2----12----1-212--21---11--1------1- 16E-21-1------111-------------------1-1--21-2----111-----------11-1-3531111----1-C2-3---5751----*--82-13821212222222--12111C5322-35351223347---4-99736533-332-1113332-5674-1-1-111-1-111344--51--1111112--1-111-1-11--11----4---------1------------------------1--11----------1---1-11----------------------------------------------1--11111111-11-33111---1--2--4-613---1---------2314234423323576E68754554444434443435-9A997689477-C3355444A47846376242211212-6666666635A54852----------11--111-1----------12474K---1-8AAB96333333321443424A5B3355--54551222461774--5232621133342273776436535--449755325934448235565Da1677A13113311AAACBABBA512256664232582426477A85647767F583765--23846------3--311-533A545253-258662563622624532811134344A2C7A2CABB98A87A-3326695---22212222111---48B778DCED31627--124315268343254946244633-AA6857357454623662122221212555533333444642213233-------23R2111133-1--1--141--------------------------21113312114BB- 4422KG8-G884PIVEADBCHFEEDDIFFBDDFECB8EEECGDBBECGDGCCDI8DEDGFFGA6AA95566878B9D3BA766699B9BDL9A9GSB9CB89B*yw5Vj*qFDBBBHFHDGMHFgOFRDj*N7TJfDIEEPGINHEMGDGLDHKFDJFDBG9AIAA976EG9AFc6AB*jCA88EJACPDEF7EHLML* --------------------------------------------------------------------------------------------------------------------------------------------------------------------------4---- * a.118.18 HCP-like
[ 250] 33131354557654655177754871135355325544644455558A52775443235651221--- 38A39213332--168766-6C--7A6666639BCB669B543643323---5561-3--438354A6D73----1---8cV5578572223-3-2-121421352834--------------331363713343AAA75433763633223111111121111143223-------1----542552213-73333334323335333366263323441--211111133222222222211222311211--11--1---11-111---1-------12-1-1-------------1-11-1-------1---------46714222212212115222443121-4F-244*u459B-AAB111521-44553341111348E8A83C9F7D84445444343A-A9C9AB9G9711788867669877C942374B7A7874844444444955-5E341111111111111111111112112111122553-48749C9A9ABA8BBBDD9DCCCD6ABADCFFA259A879677B689799765765592221221312FDA3IJD77ADAEA99E1EFCFC7C49EDBA7CBN9DF66769A383643323348J89844A726467-5-4B8DDB4ENDGHBGFIECOD1--4A53111111KCC9DG4HJJHHGDKII-GHHMHFGIHIJIHEIHGHDDDDAA53EHGJDGIKHIHHHLIFGFDBBFCCD2-A8899AA9A9AA111311111111184672BABCA94646456684444423344438889978466A89B8861111111113798E34444BC8795544646343111132A2554466--------1-1-------------------------12212121-15732 ---11-3-7533332565425A2756244443333222333325331252996546863566322141131-53211-11132234--1365634B2323352638-441C344734322124233262BQ2-8323321441362224121475781B2846A83382211A511122N233-2B37J282253444- ---1--------------2--1------------------------------------------------------------------------------------------------------------------------------------------1-----------1-- * c.81.1 Formate dehydrogenase/DMSO reductase, domains 1-3
[ 251] -----1--------------1---11112111211-------111111-1111-1---211-----11 121-211111111121111-12--1211111122221111111121111112111111--11121111111-111111-1111-----111--111---1222231221--------------133233322322---1111--15345332112222222241132121121111121111111--1-11-21111111111111111111111111--112111111113111111-11111111111111111111111111111111111111111122222--2222222222222222222222222112211111-11211111111-1--111-111---111--1-221-----------1211-37449-----45H784335643522222122227-443342428F6-9556IJIGNGJF3329528685774951111111134411112----1111---1-----------------24788-145565556572544455645556366534344111223313351536235431-153111111112422222211123111111111111112123637A111111111111-1111111111-11233434157624345533385555437346366-213311------22111311111111111-111111111111111111121213111333333333332322321-111111-111111111111--2411111335322A6411112-111112--177657722532356655643454634224322222222143343333357745666555623211111-12221122--------111------1-11-2111111-11----1--1------1221 3211872-6342334GGH9IGEDEF9FBA9DBBFCBC9A969A7789AGRBFPG9DABC9BB3343233443345332332333334545E3GACA5764486526-4I6H8878CEYTSdQKO*xV*d***8***jYWclWo*gaaUHGwSU*IT6595538B641934658542543J2344685AE8EB65A334D ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.88.1 Mss4-like
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aHPQI79B58B6HA8FAf*K1FBI9B99K9DM87D798E97FCGBBDHUVBFCBBIBCJDHO54766*44659MBHS5FC789897C --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.128.1 Glutamine synthetase/guanido kinase
[ 253] 22332343333333322243444232233532243222546543222422334222222231322-22 4596D43444421499A77-77668A767778999968EC554485437663AAC446--A57795B8974333333321259222224444-613---1866767678--------------266368535444222542223666657764466556665565365683663333733532237766142344444444445444433652344644445123333236548888896888888823343113255121112244351325222-2-11----2---2-2--------------1-----3--22-----2-111333344514-31441---1232-52132552442264333221-15276666-222266A666454555645444445428-67479467AE61C667A9FDB99A64A767899A9A8673333333374452677------------22221222-2222----677A72255598BB8A77666688C6778757E6A8NE667568532555556B86565342553333333545769546664344363353545464443553575551----1-111-2-2222222-1-1122756586556366555557555566477666---5465------24362223333333433-3333333333333333333453442233333434433333333522333335-422232222324--177777778798385833332313333333255555553346733333564514465245111-13--115669555555566655424223333343225-445633--------113------1---1-----221------21422222227833 3345895-C52-584969999A9986A765665776876455468757576CDC6B9A86553354443764656643567768683448A76B788899856557-AH7FZQSWNJF9988DBSXCXAk*G3HJbAADEG9CIF8A98AD99N7IGFHAPcAEBBDIAEN79K84656*65374K8HK8BBBBD9DCB ---------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------- * c.23.12 Formate/glycerate dehydrogenase catalytic domain-like
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nC1ABF977BD69E77AC9CCA9CBA8AD897AE956C56O89D84687o36575D88F39D6498456 ---1-1----1-1------1--211----------111-1-------------------------------------------------------3---------------------1--------------------------------------------1----1--4442- * d.131.1 DNA clamp
[ 255] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------11-----------1------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------- 1133DJF-gLD1O9Z12PJFCKKA2ECGI8AAFABC9IELCHGOBVi*12HE2FEBE*5G35E8C7992F89A76AD798888E92E8DT*i2OGdHDI*D*EXp*2GR2XVePP*QIJGFLVVsXIcD**X6XVfKILHYHM*OKMKGIVCLjMTKv*FQP*****G9NSDQKD22MEpA7FD8****S*R35d***6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.40.1 Retrovirus zinc finger-like domains
[ 256] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------1--------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------1--------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1----------1--------------------------------------------------------------1 543346D-723399C9899A7A658378878876766656475687887CB99C77AABAAA83678644A8455695887545449A9NcM8RVKABA78IAQOQ2DULn*****thYs*e*i**b*d***4***Xmm**dl*uRngbPvVR*momlsQXN*WVgSpOZVLTYK-9CI*DD97CDJMZCQAcWECDAF ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------2-- * a.21.1 HMG-box
[ 257] -------------------------------------------------------------------- 211-1-------------------1-----------1-11---111111---111--1-----------11-----------1---1-------------------1------------------------------------21---------------------------------------------2-----------------------------------------1---------------------------------------------------------------------------------------------------------------------1----------------------------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------1--------------------------4-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------- 5546*k--J762324-1513111221234211121--------22124311212111232221-11111211-32------111--11-33-1524-----41121133C*******kokenwm**g*x***6***Vlih*kk*yQpjpiyYb*gdX**BBGXPg86KAIH8O*61--11-1-13HEGF3B7-134455 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.43.1 B-box zinc-binding domain
[ 258] 11213211-------13121121-31112111--1---------11111-1---11-233-1111--- 2123421222222122244-41115244444323231322-6444A531331223435--3532528ABA311112322-124--1-23381-311---1522192A26-------11-----211-2211122111111-1-12322-11-11--1-----11-22244----------11323-11222247766666667666766355336762225222233332673666647567666666344433323322323441133322532322-111---122111112112111111111111111211---111224-213333333233-222223151-1-212-122--1-18--211-1315-274431111222314112111221-111111112-22222323232-77775567763311343411111132322222222211222322-----------------------------21212111113343432333333224433323323223--334322333132512111---21-------21213253322112-24221-2-11--23-323231-1--11-----12---------1-21---22-223122322333333222222114212---31-2------22232112223223222-222222322222222222243433224222222222222222252212222--566666666666--11111112222134211-1111-1122-22122222111212344443434511222565222222222-212722222323231155468555------1-222244---1-111312--------11--2111111211---1111111111--1- 2333A59-J97345AJKKKCDEEGFGEBAABABCBBGDCCFCCBABCHFFLOPSCGHDBDCE5556563453684462654898673348D8KEIH86675B75371CYGfpsgpkZVROIPTR*pNmT**X8kUzKSRNhNQeOJSQPNZPJ*RWVZWHNRIUGUGS8FTHTRF4C83Q684A6TWdcLcH9I89997 -------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * c.1.18 PLC-like phosphodiesterases
[ 259] ------------------------2----3-1-----12222172135-211---------------1 4CD-J1154442223DD99-9F11C7999998ECDCB88D38586721533-45612---7561O9DIJF7-------21216111-22311-311---13-436953533333333333333232245237443WYZYb---u-E8BC99655334554657A33AFB9233322232332112----126B5555555735656566577CA6552646734AAAAA956111111212211122122121----------------------111--------------------------------------------23213222222222222112222233113426332634421151132-1-4-51342-----54EECB465653A33323333321-C6C6735A44214998395679333861464558454B4222222223344-G89-----------------------------3126213644796676875554769E5555356765B7A22554C574695674388D858497111111144278F699353992EH997363452242844748*3681-12122111-1-------7337422B84586854758CA89797A77C6878D98--26567------46443434444444344-4444444444444444444566443345444544555444454544433341-724344534645---11111166567497C1112222111112226455526232B96666CFCCBBFDEDHFG32212222275649BBBBB697DC23BAAAA5541111--P6SSJKMN1111112233--------------------------32-22222222722 12115541311-22544844445554544243334445554555554456866D66646656344333-3443334413532233433546343454343322A78-2H-A9GBBFNB995BDAEH8K9e*L1QHIBA79L8AG94D978J87Q8DEBM5CG698C5BAAJ78322442Q132544BAI6G436DCJH4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.13.2 SpoIIaa-like
[ 260] -----------------1------21111111432--------11----13123-------1111--- 6666555555555555444-45667444444656565566555675575555555655555556555567555555555555555555666656664--6797677967444444444444447776667666666666722287676678756555455556667776655555555655596466565955557575775576556655565756555A6665555556566666666666666676666555655675656666556557656565556555666666666666666666666666666666666666559967666666666765665776577557567577755668566676656552555655555555556555566655555555555-65555556555575555856665665567556565555555555555555556545511111122565555555555555545556656598788666666666666666666656666888867886787779777977776666676676666797667666665555455555555554566666677564555466566555555555555555666666668667667777666666666766665-5666625-54566666666666666666-666666666666666666667666666666566666666665666666666656666666666665556555556777666756666666665566666666667666666666666666666666688887888866666666666666666556555556666556666666644454444551--2-1---1--------1-------58555555456769 -1---22-422-22224222543434433533332234244432334422332434332322322232222322233-3322222222212343232222243223-2--353322242123111-22-BN4-23411-222241311111--13123325122111324-33322144B43322C36828A3242321 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.59.1 MurD-like peptide ligases, peptide-binding domain
[ 261] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------1----------------------------------------11-----1------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------- -----------------------------------------------------1------------------------------------1-------------------*******vekbp*w**f*t***4***ephe*k**vW*gXb*XW*b****QjT6FXMFZONWA8D4---------------1-------- ---------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------- * g.27.1 FnI-like domain
[ 262] 5533453464454445456564637557455554444233333443462696A344444443333243 4484775677574487777-7944777777768999A988487656472443666745--678366A978322224442344344544433624225--35333626362222222222222254334433444355533443514B444323322222222232511312222111212316663333243333434444344445454334544433344356444445444445444444444444445545155114436622555232213324443333333333333333433333333333333544333444445733444445533342442222533335443254321423124343422466555433333355444454454444444443445-BA6BA6A75552544685446644445554444D444453333333343343334111121111111211111221111111I13536335554667C766655657767555555755555834668446556965545554534433333333433347365343443434443343535433556578433434343334434334333324243554536644I7635655545565545555466--3233422122255443464444444454-45444454554455545545454435444444444444444444454444431455545545445222434333554435645333443244442224323333324355555566565775664C622222322224546444444657745556555553333115522334511111111123----1-----1-------1-1----33343343333543 6343463-C4443345AA65776764755444468545655555875666A6A677867A794553444345464542543335367444H6A77A555556653425K3G8877CE7AB88CBGD9UBw*P3RFQ7AD7DE9A98A985C46EA87ACA86378B7235119AA557Ai987C7IJDa7QC7892566 ---------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------- * a.96.1 DNA-glycosylase
[ 263] --------------------1----------------------------------------------- --------------------------------------1---------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1------------------1111----1-11-----------------------------------------------------------------------------1---------------------------------------------------------1--------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2122B9O-9447GFHDFEEEFHEEEEDFFFEEFGHFDEEFBFFEEECFGGFGHGDEGFEGGGDDEEDE8CECDCEDD9EDDFDFCFCEEDJDFFEHC9CCCIFQUS1hXI***w***hfebhrh**Y*c***7*y*SmfX*Xk*gZlfbSvfS*hxmhnSdaMYSIGOLMTELeN2554F7684496DCE967A****J ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.189.1 PX domain
[ 264] 44352144434334362222333633311341232222321242344321483144464533443-23 1461112233312132233-332269333334733348B8253422412332344112224423434333434444548234411-2167572543-111221372323222222222122221546543444345556733453679433446663345343245567423432324222233311884657446466555555665C5CA87555386657777777853322222222222222433228241441421233554553143344455533334554445444544423333333333335556515553576BIAAABBBDEBE8DKK8AC87A525788436688B354648678336235422232222335334225A45533333333334-3382272465316776645A6676744342366566544434444445223132422222222111121111211211121111224545388376576874444455444555649447B84335643423364687823332326322222323222223BA5G56759C99818778429D711115733423421112113222122112211222A9D454445355788777B777756577B51111332111111D8BA493AAADAEEDBA-AABABDBABBACB99AAACDGECC668DDBBCCDCCDCBCBAC9987777A3-76666766666611421111133531454954662713322223444545454455555565944886545545111222121365698988988B8A124121145724251136443333-----1--4-3--------1--------12------44745A386A2351 1-22546-8348563797985468A74556433767675655734378589DG97744435222-2241343431431231-11215537C695692324477587-4H3D99957A5736644C9392Ih91DCE5423926834542373384A8473523A61B525B17814564H44562547BBA95546548 -----1------------------1----------------1---------------------------------------2------------------------------------------1-1------------------------------------------------ * e.22.1 Dehydroquinate synthase-like
[ 265] 446484454555557A57565654A5653786J6555455544C784956646457468745544365 2842311111111122222-2222532222233464354332444212122222222122543262364534222323335I22222221212222211232422214222222222212222242332342323999EF524B384574462323112222654577A411121111121122322221256666555544666674326643346433334444341435-333443423443335675472446545444972356677232445422424422-4422234254422244444444442224454444472325555545253324424554-43259222652423223313332234133222222252222222232222222222222221223222233232212233133222222323242222232222222222123322222222222222222222222222222222122231344444333243222233333333324336686334332243334433455522234322222222244443742143134233312122333441121582221-122222222222122212-231224422443233343333333443333333332-2233222122223332333332333123-33333333333332333333333333334443343333454443333332321333343333333222422222222234455332222222222322222222233343433443545544353332222222222444444444555554422223222333322521-22332222222232322322-3321333-1121233222211212222123232 53457734M96745665878487775876576677756466674657858A96688947666768766466368838452856675B8768758676575496DEK47F4VDCEDDF8KJDGNEskKmL**g-Xb*EFHFNCJNJDLNDGPHAzDFNEI54638626D8D667748768*78594RIMX6L8368CB84 ----------------------------------------------------------------------------------------1--------------1---------------------------------------------------------------1------- * g.41.8 Zn-binding ribosomal proteins
[ 266] -------1--------------------------1----------1----D86--------------- 553172222223225BBAA-AA55D8AAAAABBDED9A9A255844523443455435227693977898322222221111123233444414342--56666324143333333333333363323433335344444---6166666663433333222444498742222222222222212222213133333222222222211113222211112331112112121111111111111-11111231222213331111321111211111111111111111111111111111111111111122111222122123222222222212222222332112421211211111113221-32614244211211322222123322322222322223-334344442631322244344433225245543333556333333332222334211111111112222222222222221111133251222245444453233333563333344555565225553553334666333732333222322222324664C78422312322215554443449998FC27534122222-212111111142122456656955684488888576888888678672-34232------65444534555443444-4444444444545344445565534454433333333333332644444442234444443444411275455555544995922225222222233354665574556699998A89B777758774333333333566877777678AA676767745522221121AA66553332322222311111-111111111111111111112131222222234 64339AA-N754687588766667655777767755776756776866575576666466456965465656566675886666874345A988778667686IHJ3DOBSLQJLMOEBB7DICaOAYD**P2JNa8CB7LEEJH7FDE8HB7RHJIMJIF8DIDBANHDQCIGB98C6j76599MFJQ8ML8BHCDB7 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.112.1 Glycerol-3-phosphate (1)-acyltransferase
[ 267] -----------------------------------1---------------1-11-11----1----- KCP---------------------2------1--------------------1-1----------------1---1--1----8578ATSRJ-R88---7M8DDXBR9H--------------58899A8AC9AA2--33-----72375411111111232112547A7131121141121-4144227-2-------1-----21--------11-----12122111421332221-2222312-12-1--------2--1---1---1-------1--121-----------------------1--------------12-7-----5---143334---1332-1--2156222122-2---1-42K6FI7782222296A8D84A7677311111111112-333253341261422543474323396872141121221EEEEEEEE5LKE6B6611112111221112221321111111111268IA9BBA4ESSUVVOJGHJIPOPSMNNLBLSLRGQLW35HIMACBGHTFD8H4FLIAMEICD1122222A7B7AF88I577E444955719F7CBCECFCC9EE76DA6433323323444445444A649BEH6579569686636565366A7784688996--28827------555A3754786566865-7666655567776554556867BE5446765666665556556613866451-634444444444--2922222CFFGG7728222212112113132AAABA9922398JKLLJLKGAJIIIB9EG333333333A5669686678BD88GEDADBA677111131B3CC88881222111121---1-1-----2---11---------1-32-22222AF44 --11245-82541222-3521442-12111323-1231---1311144-1132523131-2-11-122-------11--11---2--2--3--937-128131-AA11-1R8AA5F744556CALM4E6Fm52E9H2561F69C525542F24I6974B59A5B535B57616H5152143-3-1231G24311B5341 -----------------------------------1-----------------------------------------1---1---------------------------1--1---------------11--------------------------------------------- * f.5.1 Outer membrane efflux proteins (OEP)
[ 268] 221222632222223332333332655555541121111111121264325A7111111113323123 21211---------25422-22113322222242331143333221---11212411---112121331-2----1111111511222112311--1---2-1131433--------------13312232332243355111354435225222211111112213264------------3224422-135333333333334323124434332333-1--------1111111111111111-1--12-11122112113311221-1-21------------------------------------------1----1--1222232211221-441----12--614-6223-31223211111--123422C1222243C577963323322222221227-4C5487943821244255A465352211132533332223333333334432322------------1111116131111--11131281111-175535584565754666664523D443---6412422213233131334-11--------11341149541458143556-626546334234244661-1-1---------------21113332211231122321111111111121111211--41131--11122342212222222222-222222222222222222244422--13332333333333323222222222-222222222222112211111224351231---------------------1---5311111111151212121-11111111133221111111111--2222222311111132222222---1-1112-1111----------------------111111111113-1 GE67YUC-aAB3EFI697A988688866666664766756666666777B799M46868967732943434622355455A333437A6HLF9FIJ66664A8E7928yKiPkRWZJKOLONYLhYHcJ**V3dQlIOLJcNQYOIRKKIRKEjLYQNVEIHTwMQSQLYdMTZC5HHI*KNKBHiiw*7*xGCGBDER -----1-----------------11---------------------------------------------------------------------------------------------------------1---------------------------------------1---- * b.15.1 HSP20-like chaperones
[ 269] --1-----11111-1--1111112111111212111111212121112112221111111-211-111 7DE11111222-3-12322-212231322321111112111111----111-121-----213-22222221-------122153874899617331--38364C7A361111111111111112437224443422211---3131131121111211111132211131111111211112111112-43588888788687778889886788A38A3521334444J21111111111111111111251-2-121-1-3311---121-----222-----22------------------------111111111-2IG6LFEEGFEG8F83O885223261--8214-TO6EC93E82A8B311199B22231---17598745469469222222222121A7978783486-A333558665858B2225599899535111111119332286A----------11--11-------------23576444427FIJFJFE6777EEDG8A8859FHFCGFD12DFACC967CE69A376A5B7655-------442DID7OdEHITL9MFKLT2PTMNQLcEFJRJRSkEQ2111-11111111111111133111BAA88998H8889AA99A9CCBA9EB9ABEGD--179BE------B767974BAAAB799A9-AAAAB99B99A899A9999BA977763A99989ABBAB8B89A986798883-666777766798---2-----111164KBI222213-1-1211114436417232G8EFHFFIGGCHHHG9EEF1--------5879A999A9CCDDC55975765551111-1922233331111-11142-------------------1------23123131116615 1111121-621---2221112222211---1111--1222122-1-11422212111--121212222111321153333111211222-212211111-2122431254c574448344335373356AV4-36F3534433343342364373435779B29632332E35B51321K12152748A1623274581 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.1.26 Homocysteine S-methyltransferase
[ 270] 33141145334334342444454441133554444444444444444555986445213124113-55 4453743433334345433-3644393333335333558E44365651333444533311354356868443333333-331634333333324---221525663644----------11112333444333444445444383334344333333333333333436333333333333344555431446444444443444444547645444356341255545368244434444444444454451-1--1-1---22---2-1-121324-------34433333333232----1--------33344433323B-6C222222232355663---5-31-35343676343433344531-333586671332397ABB5366775555555555448-55955959A831799775B998BA88864769456676943444444733454341111211111--11111111111111111444D449HFBEACCBCAA5555AAEG555526A8GECCE35BC755888D9B6GF575344496456555533474436644334334443155548654544542734533333333512433333323333344558885837985756757677775555765-2-56331322238665676A888A88888-887878788889977987A686654568786868888868667776577775-66667666676722141111133334657A333425-222234448888867557948887679A666788888422223222354647777767467777777777755663332443333--------1------------1---1----11-----13--3-3333531 11--224-411-125AA75AAE9GGFF7668A86666666556677658B9CFD78997A675455554556756551667555555556B6A66877765868A9-68478935593452324453557e4-4493333424433434334484643625C25264B35866433344*3323384DC6984466766 --------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------- * c.8.2 LeuD/IlvD-like
[ 271] -------1-------1-1-------------------------------------------------3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------2---------21------------33---3-----------------------------------------------------------------------------------------------------------------1-------------1-2-------------------1------------K---------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --ON-14--------------------------111-------------1-----------------------------1-----------------------------3*v*w**wutpny*w**l*j***5***jzoc*r***g*ylg*hd*g**tnX**od*XY*YR*SX*v-LP--212I1--6-----9ffan- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.68.1 Kazal-type serine protease inhibitors
[ 272] 334221434444444532432322-2222124------------311F12422--4-3352345--42 6793Y11122211136555-5533455455534546317365133814-652637525--FE51N6AGBH1-----11-12132-1--1232-2-----1622483654---------------1--1---11714778A-11F3375333811---111-232-79879----1--4----N8A24--132666666967495597859AA776873335854557675952--1111111---11--1---121231---11---22----1--1-33352233--222211132313333333343333144--212123415B1212412B1737223675D32-1633421-2314441432325362-42111-----3233312233233------------322-13-232--122321263132442114-41211112111111111---2--1------------------------------1322-2211-9666796766533269888285524334--446414--1311-21232---4--11111123431-G14------111---1321535--1232AE-51--2-112----------------1--21-3237244-E5686A43CAB2C85623C--32111-------2-11-1--------1-------1---1----------1-32132-----1--1-------3-------1-3-------------2D-1---11112-511111-1-3----112-2322211---21234243513333314331--------1-112111113311156ECHCBBCE3333--1-11---------------------3-11-6-113-2--111133-22111--1-2-5 4213LKC-923246CKMJF7BC9CE9AAA9ABCHLKOKJKLMM9A9GDPoWVbYPLWQDACDG44334245455634264555555445EfKME7D33334L6OVS2BbUvLFEIGFC898AEJJJ8KBV*J1NJV7B9AF9BC77A898D96ICKBCE6CFIOB9BH88S9CJ8-FW6W232NGNxk*Gx*H7DICEN -----------------------2------------------------------------------------------------------------------------------------------------------------------------------------------- * c.41.1 Subtilisin-like
[ 273] --1-1------------1-----11--111111111212222422112234331---11-21112-1- 3453A53455554474343-43334844444464448755323435543445645326225475857A9743222333334434443355565645-114634574845-111111-------2343333435434445422274534544C4444445444464444544444444444446554344324466666556665655545765466633455443333337446666666666666655556321232321212232321333433332222222333544444444442222222222222333333333436345777667746487335444433124554366344445445454145557645465555545584455667655665666667-555557588C647AAA67B666777577476755564784444444445553577-1-11111----1111111111111----3789847877766778866665557577774688756571344844544748765574533364444444457554547853366554776367656555544448525564555555554645444455566544886665765775555565656655655544-12554422122265964646556666666-56667666665666666686567777777887787777878878554666552755465545565114534333555555557333333334343335444843567556778889787888668895454464445555B666668878845545444554444335333333311111111312-------1-----------------66755444444564 2221567-62233343553357476763434443334555655244842355674332433433635523433344425453334334749354333443242366-5A7I88E87A3555454EI4I6Ki7295C53549458635443647836679CFB4M64396A375CG4565i333479BBD5B675CBAA7 -----1---------------1-----------------------------------------------------------------------------------------------------------------------1----------------------------11--- * c.1.6 PLP-binding barrel
[ 274] 22663267777777785645674666654756787A99BAAB97767866777B66677475554-44 5783675444444455544-45446844444476664565486774554655445534334544465545422222223445565554445535552--4544564454---------------555555455564554466648A675555556665755576445656555555655565333445424354444443334343344444543433333433333333452333333333333333333343-33334-3-3333333334333332222222222222222222222222222222222234222333365545666466645463334444645334455744A55353774465734565444533333586574455654533333333334-54546556334343343334343476555444454434466666666555454455554444444-1-------------333344545555445655555555545578555545578558745464674355757655586644454444444556666576576576666665676667656667555567556566665716111111176656656755546454666666566776666666754-246451--11166556746666666666-66676666676664666666675466676777677787777786666666644755555555555--544444455555565466767635545645644444444446465565554555565645433333333755464444445444665444444444444464554444--------4---------------------------31333333365653 1121555-613-56443435444455333333344344343663436434434463356334333333134334333-43443333343483363833433333771552L66575A665678587994Gl6259H362585661456467337586965AA6B546E68C67665455Z6437464784685995644 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.139.1 PurM C-terminal domain-like
[ 275] 2267327777778777455666666665475687798A999997877766778A66677475554-44 5674655455544455544-45446844444476664565486865554554444544334545566544433333334555565554445435551--4544564544---------------5555554555645544666488657655666665655576455556555555655555333446425456666654545564555655455545553533344444563333333333333333333343-33333-3-3333343343333333333333333333333333333333333333333333333333367756888678765665555666756455458866676355797785733664444533333586574455654633333333334-54546556434343343335343486555445555534555555555555444454454444444---------------333344446455446555755555545568555545577558745454674355857665576644454444444555666566576576666665676666666666656566556666665616111112176656556645545454666666566666666666654-346451--11166556646666666666-66666666666664666666675466666666666666666666666666644655555555555--444444455555565466666635545544544444444446455555564555556545433333333644474444444444554444444444444465444444--------4---------------------------31333333335654 11--543-511-33333333433333343333334434444443443334435434344333344433133334343-3333333443346435534443354343154396546586466565965A4Dg6258J352384462666535448464665886A545C78C64554346Y5443452664474475745 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.79.4 PurM N-terminal domain-like
[ 276] 22-41121-------2-133233531123533247648989A7D836A74EG862333333-111-26 3462744223223236677-7822A7767779876636553566332-4112343234--4352436454222222222-1-58556655756312---2425346252-------1111111-7958797768777777224258DA74583544222112652496323333333333336546633251511111232122223234664422132134135555554422221221222222212323642357424442322764133424342222111244111111111111111211111111211333111276366444444444423AA3552624325316A787551376657472--3566557-1111457589556658655555555553-55545549446-355433454344675564423434533222222225451336611111111--1111111111111111111-4433153344577675355557759766657668363623664422474257248585656551111111338568287544956877781675969579435434773--2-111111-1-----1-24355776874635534645555544655555455661--564611111175557856666666666-66666666676666666659B9674459788999999899989756666665177777777767722-4222225554A3353222234122223222333333322244342313363221145351111111115533633333444554444343556333343B2772223--------1-331112-212-2-1111-421--111-2211324335923 2-22222-4121878643386758A8933443435646545555346585BBCE65679555325224-424324462432333335464774757657555459912B46FK8GH47A95787GJ7NCh*P2SFQ4AB6E9BE96A885C55DBD57B399B6362B3724F6-3866*33374DFIQ5K968AI996 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.58.5 GlnB-like
[ 277] 4413-675766666642768787B75553764A85442435467848A3AEDB122121245667-11 2896C22222223244455-573358555554788857DA567235243112244622--444466A79632222222117673333255554844---2934364725111111111111111CEEACB99C9A55599KBF86459655634444353334634446413112223212166455333655555554464555445853346553685554321222255233333333333333333332---22-------11221---1-1111111----11-----------111111111111111111111113763CAAAA9B96A8665535459331-532F9PQFHF434HD33351-14B5444311111595763348566755445343444-6545665656315554765655646533447666666562222222275535847112111111111111111111111111113234423434766666598777AA7A899958686787847567C4599A5877786A8465893333333324AAB1OaDDHMHEHEHHF1KEJ6GBF67FG9E5ADU53452665552434444334456635486336363645699A85A97989887B9A8--178AB------6576771A999A9A9AA-9A9BAA9AAA9AA9AAAA8777664459889999A999999995878888811566666666666111311111233384674222213322214222333333333455778886657778774444222232223698988888575895334344333222243B1223322--------22--------------------------35523323334522 22--212-411212222111111211211121122221212112112212222211211111111112112112211-11111111111211211111113-1212134234553312322142331616N3-44623322122-2232223232322415A26244623222511322c2223333A81572236231 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.1.2 alpha-helical ferredoxin
[ 278] --111-2---------211-121411121231227576455755322586GAA511-1-3111-2-1- -2314123---11121111-121114111112236322331423321-11113341111153323353243222233322222112-14444-411---23433333-4-------1-1111127A5666755985773422341556455534223233323424547613421223124114-1111--114444545444544436233214461-16213222223512222222222222212112121212213--1232236232121122433222312211121222111212222222222233211122241D46A6657777564654455465442231225CB961113642232-2-22243221121144X78217DACCA22222222226-44344255B5214555868A6556631228547367522111111112-111347--1-------311111111111111-----121-3S****85554832222333533443255G****7J545G8rik*e*6**7C221113144434444111321A95735365356429787345873233532533321----1-1111111-1-21-133334132162113765622233362444634--21151------41311312222232332-2222332242232332334322321132323222222322232322222322-322442234443--21111112222223572223121---111132322221322535435433453333433311111111114555121123324411412111121212--6-221133--------1-----------------------1---2113124112-112 1-23524-841225144642432351312413222424344336131245436412343456134333423231-13-4342223211221445257132126234-268958389E52543489D47BFh9-87F445364385-555453355861N45548645326B52733CD8*77748847Y364885A568 ----------------------------------------1---------------------------------------------------------------------------------------------------------------------1---------------- * e.26.1 Prismane protein-like
[ 279] 222114756667777724324224533435731121111111122-2-11342123224434341--- 44679344445322C6777-9A11A977777399A97EOP56467655676287E4543344G577BB85412224331--25121114442-2111222117434232-------1-1----22313321222233312---343444443123322112324244464212221212222533442211535555554536565456633555552415587644444463333333333333335967573718713322CD546756887266664464445543334323333344444444444445663336666414-444444344332533112262-123-11153162235134443144217744533333778455554444455565455556-7777979C5A53655698E878BA3C8666464544666333333335443434422211-1122112222222222212222215467-887697BB7AB77777AA6A88883776F4A892334445366657583365311133322223256444336A45444445333142525635222424314111-------------------21366555895246551132115131122111223--1653511111142326335555555555-55555554555554545555432344344444544443644455333334531455555555555112311111334346575222212111122222433442556523456664554557733325454453443333544444534445334534323222222335533221111111131422323-3-62222334352233---22123313336511 771153C-E56155344743535656354233334213123323543535577A3335454422223214342223323524443233448342345534224747-6C6FAI99F8A968899KG9K7a*F-GBU7895F78D878B78978IACA8B6AK7C86AD67BB9C76E95*46567BCGF5F98B7B65A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
[ 280] 55342244555555642344335673442242122121111111213251222333334342116211 14423312221-3112211-14111612121158884545223323332222654444--433-24664341---1----1-622122--1113111--2346573124--------------1-1--11----1555661113554532254422423323431443442211111211115334444245455555356565544556553455465662331-----6344443433334443321125-2-------1-------------------2--22-------------1111111111111111111111-3222-21111311212132-212321--32-2233335313431124-314113221--111223442212234244454444445-566457453C1-B44756777856632-1465767775D111111113----212--1------1-----------1---111131-41148655655957277865555888857965554512655354334894732222111532222222131433355432322142211344111221543456451--1--111--1111111211--111122-341443532222223222213235123--12322------21--1221112132311-1111213131132111112554114422222222222222222311111111-2--------1--11--11111222213832--------11----2222232114211676659775474311122--------23332444444535632322222221111--21332343----------2-------------111---------12-1114-1111-3 5A448772J76276978DAA87BFEBC779A8A768AB899BA666ACAACBAD99A66AB98897AA3878A59A869689999C488IGB8DEG9AA7AB99DA2CbBRJOONINFFIDHKIfTHhG**U6fPcCJGFMHJMHBIJIELGBVHJGGIHLFBIFJDF8BDEHG94EEC*AB8BCEFNK9KGGCCCDEB -------------------1--1-------------1-------------------------------------------------------------------------------------------------------------1---------------------------- * c.42.1 Arginase/deacetylase
[ 281] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ C99AFCA1cGB765445525555453531333355426364663434466536556656466666666356565467677666656455333546774652259A35BQ3y******sZjhn*u**h*k***K***RqlZ*i**nSvnab*VO*pxtpyIhfRXWJ8qLQ*QUJM698B*9A956KPVa6OC74AIGJA ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.16.2 Plexin repeat
[ 282] ------------------------1--2-2-1---2-2757953-51A16112-1-1-31-------6 -2212--1111--1-1211-11--2411111132221233-11141---221333113------323652----------1--12-12----------------1--1---1------------11---1-41-236634--16-955K661111111122-145-76F61111-111-11122-----2-5BAAAAAA8A8B7AAA99CGFCC9BA676G755222222MO-111111111111111---13-1-11--111111111--1--1---11121111--1111111111112222222222221--------12JEDPHHHHFFH9CF79CC52225A6--512A2IJ7A8677443473211-722331-----11IGH1-3CEADH----------3-87E6887B-4--666A88799A67I82--333556538311111111-3311WAG--------1----------------------111-244--GGGHGGH6899DDGIAAAA6AELG7C9811BDD96D46H44CC197E464ABE-------2223CU5PG8G7EKFgXPNS1JMONFEFB94566849D977715655551411111114D24411DF76B8912759IJHI78CFFHGEDBDGNL---1427------ABA93634555455544-55544565445542343388669A---757567776776665743323335--723344423444---4-----11113-F6I---1---11---11-1111---11175AAA8HLKIFFDFJDBDE---------B8MOJJIIJHJILOP5556667444------IQ885577---21-11H1--------------------------2325445223-2-- --------321-1-2----111111-----------------------1-213---12----1-----1----------------------1---2--------1--112G9HCNA84422685FF685Tl83FBO55669469556434A44B4C769435AS946976922D6----1----172-5-252321-37 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.110.6 Sensory domain-like
[ 283] 11111111111111111113113---------11111111111----1-----11112122---11-- ---1---------11--11-11--1-1-111111-1-----1----------------------11------111----1-------1-1----------1-------1--------1-----11---11---------1---1-------------1-------121------------1-1--11------11111-21-342213--1111121---2---2----2--1111111-11--111111--1---------1------------------------------------------------------------1-1--------1-111111---2-1----2-111-2--1--------1-11----11-1--1-----1---1------------1---1--2-1---1---1---21--1-----2--1----11-------------11---------------111----1------4--1----11121-----2----11-2-1--------11--1-----2-12-1-------1------------1-1-21-1-11-2-1----2--21--211----1-------1---------1-2-1--------331-1-112--11111--1---11---1-----1--3------13121211111111111-11111121111111111113431111-21212222222222121111111111111121111123--2-------1-11-1-----11---1---11-----------1-----1-12--1-11------------1111----------11-2-1-----------1-11------------1-1---1--------------------------41323---- C778LGG-nLJCJPKFEKEAFJGEFGDGGFABAGCCCD9CAAFEHEABADCEOF9BDKEEDDHDDFFF99DHB9DCD9BGADDDAC9B85CBECJJ788C9DDNGJ3DHI*o*jsxrRJNPMcT*wP*Q**i5*g*JUONoPVmTMaNLEcDDyPhUUbFNOKQNL8jKSNRULHCGO9*87886fSYiJYNDEHGOUC -----------------------------------------------------------------------------------------1-----------------------------------------11------------------------------------------ * a.47.2 t-snare proteins
[ 284] 1113121111111112111111123111112111111-222223322311111113111221113111 3442833322231322244-4422444444434444343416642224322-323211--542222223331---311121321111122331122---1522142313-11111111-11-1-1111111211112211---3233442222211112111121144432121111111113321111-1248888877997997982244338984223-2211111292433323332233333433453---22-1--111-122---12--11---12-----1111-----------------------213----443322222222122243322224231232221324373-2423214121132222211211133324212221111111111111-34235242132-11122154422211221213212132221222222142411111111111122----------------1--13111133335211113222224344222224144245512433324214534255333332222222332213523115122642223331353264554357488332212222222222223222324322224336332242333333344634433363431-12333------33462333333333333-3334343333333333333354334534433333333434334322333331-333353333363---411111442311424434222222233333222222233242323233462333322332-1--21--23433433533433443333333243222113-22------------1-------------1--------1-----111--1---1221 CA88FGC-gDF8CF99AA9AABBAB9AA9B9B9998B88AB89ABBABAABAC9A9999AAACC99AA59A8BB9DB6CDBBBABBBA99E9A9ABBBCB9ICBA97BQOQNNHIMNEEIDGDEWPCRFu*N1JHaDJCDKGFKIEFECIJLCWCPFIDBHCGIHB9A9FZDHEB8BCE*DBBBCQJNUBMFGJEBCFH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.111.1 Activating enzymes of the ubiquitin-like proteins
[ 285] 11111111111111111111111111112111142-11111111111112638111111211111112 1-2---11222-1-4------1---1------1-----22---1--3---1-----1-------1-11512-----------2-----11------------1-1231---------------122-1111111143342---3111111112211111111111311411111112111111211111-244999996665969966B8336769534378324666654157776777777777755522583222233265433235432432223332555322333333333332222222212222433222333311441544354224115331111111212111111222111121121-58-1-1331-----1123322145113----------2-23133524-11-111---2-1---3-2412-1---1-1--------------12111111111-----------------1111-1122-----2--111--------1--------121115--11--22114-111--31-4311-111111123--11----1211111111----1--11-111133---321-111111-1------------1133-1122-1-12444422343352322524---41-2--------1-----------------------------------------------------------------------------------2-----211123212---------------11------212466654665334523444111-11111-12223333344444221111-111------1-----11111111111---------------------------2212111111-1-- 1231562-622398-33221212212322111122232122221222321223232311232111212-2222121221211122111112131232213--12221BA9S*unvu*edjZenR**g*k***6***hkcfxbl*hWdpda*kb*MxZakBEYRCBYGB68EFOE82554J42146CEOR2T8357JAF3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * d.17.1 Cystatin/monellin
[ 286] 33111-3211111113332221124222225111111123222212111212-233353333232-33 438261122221-5421----41147-----3355521C73625322-1-11675222--343345856731111222--52622333665538441--4725643734111111111111111--1311--12143344111233433443222211121124225452211111312112452333322455555555545555557666445554553843443455552444544644444449666732742246-2-662223154286232433211113311111111111321113212221232222222225827833333332452277422255422444517812114313A9641444139336-1--176DDE2357989555565563657-7897685CH861EFF7898ABACFA94626489A9A858222222226883135311---111---------------------24565469849899A987333388HC776767A8GACDA1387578887C7H3C9242321132--2122235413335351-123223321333232449333324342533333333322222222231442335674654344444565354555465464532-12434------67645435556575645-55567655555755555557B9565455555555555555555A6644445225666666666661133222223332254992223351332332225565556353C499998CEF8B9E94AAA223223222234456666665566423323333411112224444444---1---1121----------11-----1-------41253242323225 23--464-941-334AA89A788HCC5BB9ABA8785DBCAADA79857IDDJM57B87B9BG6755524365365645667758B364AD6A796B798627987-3C5D9534652222543451734P3-3652642944562434253144845743B57854A35939B527A3M2235ABCMNAA653DDAM4 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * c.91.1 PEP carboxykinase-like
[ 287] 22323122222222235555533322222322--3111111112213143333-24424241221244 4896857655566465566-63336564566633336756556848524562645246226343576755333335442112222544213313112--131324124211111111111111132222222253666672225435444421133333332321144732322222322224413333141133333344144544442221134411122111111114211111111111111111111142133112234511222221223332331111122222223222222222222222212122111222131144333333323213221111211112212521324562133333311363733311111124333222233322222222223-23322425324132234224443232121123111111122222222-23314321111111111111111111111111111133322133313344443333333355333323334345423122332434324412226222422222222224633326132231342322575655667447435373333333333332333333332354114634242234411313315111131341331-111131--11164445544444444444-4444444444444224424444444446555445543656566643344442144444444444411121111123222432233333413333313333333332233455552542332322222444444444224454444446278332323322211112125334432111111111-111111-111111111121111111156455444444421 2211A78-843266AAABABCBBBB8ADDABABCBDCB9BBABB9BBBEBBBCCACC9BA79CA97995C9BA69BC5ABAAABAA9A8CKEADEDD8D887BBAD3BC4UCLEHCD9898AEAMK7OCi*J-JCWA879FBAKBAC786EA7E9CACBGDDBIDC7KDFP99D96989W67599EECJCBJ6CABBAA -----------------------------------------------1------------------------------------------------------------------------------------------------------------------------------- * d.13.1 HIT-like
[ 288] -------------------------------------------------1------------------ 1-2---1----2---------1----------1-------------2-1----1-------1---------------------------1----------6-1-5---2-----------------1--------1-------------111-------1-1-----32----1-----1-----------1---------------------------------------2---------------------1-------------------------------------------------------------------------------------11---------11--11-1---1------------E4-------------------1--------------1--1--1--------1---------113-----225---------------16--------------------------------1-------1---------------------------------1----11-1----3--------------------3--1-111-------4----3------2-151-----------------------------1-13-22-112222214--12A3--18----------------2----------------------1--11----------1----1---------------------------------------------------8-1------------------------1-6--------------------------43-1-------3-1-----------------5-------------------------------------------1----------1-- -----3K-1--1----------------------------------------1--1-1-------1-------------------------1-----------1---2-1**s*******w**w********9***x*x*****Ykx*v***s*w*c**CMJTevGP8KDVBBb4---1----------1---121--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.1.6 Cadherin-like
[ 289] 33351365555555552344433343344534332444433431214123444445536453552-23 5572434433347345566-6433856666672444644446454453444344442533334554437544444444414422222254542433111352335463522222222221122223233332323777771225324333331222212222232244332322222222234334445344655555445454544465555555456537427777774548888888888888787779968588576558877886886866676666777677666667767674444555555545666666666643354333333333344443333343234334344443444344444226223322233333233323222222233333333333-443443344435333333444533332132333322223111111112112322322222222221111--111111111222223323322222333334444443344444543333343322443432222223322222334323334333233222333322222322224323322222112145233324344434322222222222232124545243245444545454444454664462-5222221122255444444445454544-443444444444433443454454564545555555554545544444444314444444444543332444443333323324444242444344442222112222232222322222232222244444555453664444444434443333333343333223544324322233343534--1-2-------------1---11132322323333532 2212488-G772558544565546465664555486454444454444457558455576564444552446434652556555654565654476857447466635H8N89A9AC79B6A9CEI9ICOyA-IDN7AC9DC8C7699A4FA4D966576B97AA9659668D953956j46445EAEI7KG5A67A79 --------------------------------------1---------------------------------------------------------------1------------------------------------------------------------------------ * d.58.26 GHMP Kinase, C-terminal domain
[ 290] 33212323333333352322221221111-13111--------2123231533-21122112222-12 44A2722222222382344-44335G544545645456C94746A4333221525113--44625549873-3333222-1133244445453533---15-43A5745111111111111111464544333763226422234734455333554243334545364333333343333354444321323222222121232222232232222142111122222254222222222222222111131------1-1-112211-1-11------------1111111111111----------------111---12423422222222222333111131211-253344643153-231134--22755542222234BEC434A535333333333334-785674866443A99B556DB754B45665666577645444444445443534311-2122211--1111111111111----175A55454244667957446455885444447773465256553653358758845434334422222223343333C583432232333255544456533334C452444433334364666666664557563454755465422232233223222442471-15557------43754543444544354-4334444445444443444334546545755555555555555544433344164445445555511442222254445679611111111111111133333344546599A99B8A89A985979434423423222222222235344434444444523331144885577331222226311111---------------------27433433443743 1---664-7222554AABBCBC8GFE8A9364568657555769A8HBDKCINK9BAB8B984563655544A6987677555567556578A5658766878665-6G9F8D78BG8477777FC7EAY*D1GBL876688A8B4B976A69F7876A563677A99BGC56D53685*4446678FFCDEA37656B -----------------------2---------------------------------------------------------------------------------------------------------------------------------------------------1--- * d.160.1 Carbon-nitrogen hydrolase
[ 291] 2212324489CA7AG535111113C55B4495111221111211112311333222322224644-11 46R2A32333322235522-23223A2222224333569C21226G52333379A32422215395I5C4511114111221921211444414211--2443334D2411111111111111234131242222332752114A254264443332234332222555423222222222255533351243444443553454545436645446335662432222378322222222222222222224-2232235-322-153111222332111111121111111111112111111111111111111111112332711111112124122111212122123215424113331233312152674441311122C775343433344444444458-22943D44HG21DCC1B78EFDCC55441354628766911111111133111221221111111---------------11111137531765BECCCDD8444499E9765835C8D7B971266732544B5I4GE2331111211111111211523563122121121111322311131221248212111111111111212212241213212372254282222222125223222542331-3212121122286DB3948BA9899B88-9888BAD8979A888888B9B9FE243C9BBBADCCB9CCCAA86447776326778766666681122222222222312933336233222233323333233131925545337834564284762V2N3pp212343344445333333675774551111111211111111111111212111-1-111211111111111111133422242421234 1211385-623311155748877A88B2223335543343243344859A79CD48648333333221-A33434352252111324335945453A67764228613B7FDC77F986C55A8IS6F6I*8-89H6657A76B537977763F9878A4677A666748D24732123H24521ABDH5BE236666B ---------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------1- * c.1.11 Enolase C-terminal domain-like
[ 292] ------------------------1--2-------11------62-24---------1-----1--1- 34A2521222111111111-1111121111112444322116665331344242322111673254389A5211123311152211----11-1----------22112111111122222222---111--22-ABBA9---D364498741133------55346548------------11322--1233555554453545434354434454242421122222262111111111111111222221111111111111111111111111111111111111221111121111111111111111111111111332442222222422322222222241222433233343232222221-35-2----------22-----1---1------------1111-3-1-2--1112-111----12-1--311121-12111111111----1---------------------------------11------1------1------111-------12322--1115443344437234523421----------13771A513112-15--1-23232-2-122224M14-------------1-1-------21221122152-212-----123---1--21-32---1121-------3----2-------12-----------1----------11---1------------1-1--1-------------1----11----2-----1---21913------11-1111---------1213433332223411113211----------211211111-1222112131122211111112BA6555--------21-----1-112-111---11111111131-1-1-111122- EFDFGEG-mGE977B67999BBC9B9978779877788888888997778D999677977778897783B98989985988888A87876AC7BEC66686B6EIW-B*EWVZPSVLIHEGKLGYSEWI**R6YNmCGEHTGIPEGJKEGLFDQINKKKAG8JJGEAOCIPGHKD6UcG*GGGTPp***A**NOYbVTa --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * d.219.1 PP2C-like
[ 293] ------2-11-11111-1--------------------------1-----------------1----- 3-32G4478891117A666-68--9j656667CBDB9Kmf1C3EHA914564LLQ758--11C4C7UNJF81---1----1-H-----11------------1-212-6---------------------1-1--13353---16----------------------11-------------5-211-2-624444443343444334C38824445143182-2222215B211111111111111211121-1-22---------221-----1111112222-11------1----111111121--11--2---1111292392223333131463322126322-16422AA2431-1251112-2-1-1B993-----52OGH--892372FECFEFFCDEN-68M66Q7JRa2-rZZOXVbjcdfcQK442GFRGCLNFCF222222228551-4-7------------------------------14E2-DZUHNLJMILJF8884IIaXCA8867MDhKSSP24A99A8A68PAY8YR695----3-2222222---555-4E353442163331424123312-----115-11------------------1-----33646844C574454546665666474655----2-1------8BG95B4DBBDDDDDDD-BDBDHDEDECBDECCDCCECDCBC446E9FBEBFEEECBECBCD999CDBB6-566666666666---1-----1----45KC1114131222213329A8A84911-84CCCDCGFNBGIIJ5HIG----------334833333557563322222----------2--------------1--------------------------------13121--1- ------1-----12---------------1121111----------------1-1-----------------1-1-1-11----1--------1------11-1-------1---------------1-13-1--2--------1-------------523312---1-----1--------1--1--7-----2---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.78.1 GntR ligand-binding domain-like
[ 294] 1111111111111111111211114223324231122111111222121222211111111---1122 1344856666667757755-56447755555669896655354754342443444344--666285655652111222-11-4213223324-2--1--12322533521111111111111122334344333455555---5287878866666434454667655754444544444443212211132333333343333433433222233322232431111115222232222222222142232111-11-1---11111111111-21111111111111111111111111111111211111221112221-21111111111-1-1---1---11---11-121141-1111-----21-3336665233346576876567666888888788881777878775872AAA89AB99ABB67554568989966555555555777557662222222222112233222222222223246665544444344343422222235222222333335522222442222324422243323433333333344443211214444443352232322232543475234222233333223111111122333555554334446344444444444444544332-3443611122254864445545555455-5545554555545555555666655444544454544444444554455543253444444444422323333311113254864445534432433433333332325333334343344445455222222222344464444444444333333333322222223555566111-----1----------------------1---1-4222132114411 --21853-A4626555568565776675443344443343333643548797A8686769A842322452642327445443333434237354744664434545-5P5HHNMKDE889A8B9GG7I6j*91IBL799AE8CB8887B9DAAJAIGBI7C79B6BAB87H5988BBBE*DEC9BUELT9GFDG84669 --------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.7.1 Carbohydrate phosphatase
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b7-B495243334511322352242524524A44411612513442443J2222522653632252236 -------1-----------1---------------11-------------------------------------------------------------------------------------------------------------------------------1---------- * d.41.2 Nicotinate/Quinolinate PRTase N-terminal domain-like
[ 296] 22--1-88A8898988-43A4---62243232-----------11-1---2-2--------3541-34 33A3E226445212BTL55-5X11EP535558YVYaB9ZU3EBN544333328593422298D366CBBC5---------1-922122-----1-1----3232323-3---------------321526222355554311144GAD7AA625443232426A2AACF723222222222254334---2233333332443434343333333332422223------242111111111111111111------------------------------------------------------------------------1411111111111-2111--1-111--2--1122---1-11--------614B775-1--188FAH6354326322222222222186557B854A7-633586B6798C5D4353C8311273677777777266653431211111111111111111121111111122V*419HC9CJGIILLEFHHFMMIMIHKK6EPEf8NF924988BG7859EE6KF5A563553211111113333CA4121--1--------33425432-4444F9-1111111111111111111111112133322365317231111132211112132123---2513------3212-224441411134-344441244441444444365722243111111111111111144223334--232333333332---3-----332367479---------------B9A8A5A1426499A9797C4ABC967651--1-11--332331111123433536676644522222221221122----------1-------------------------1--1-2-21142-1 22--112-834-2385595A896FAAA766645223222222266544456AFB5584544512311112113121111112223222239455343334434455-6X9PDEBFE64345264A6392GX71A7923245466833523C1354657C78738675A36633645GG9*CBAHLJCHK5D8985575F ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.33.1 ISP domain
[ 297] 22121-11111111111222222122222222111121111112222211332111111111121111 3332444344443443333-333345333333333344683436333444444445333344344444444344433343332211-1333433333-1433334333322222221223323331222323233443244444241632212222223222222243223423333433332221122223444444444444446443444444433363333333334443333333333333233344534334344345533443333332223433433333333333333335455454444444333333333334454555556646545444434444224443233244333344444311132333222222322322223222233333333333-43333322332-333322323333223343333333333333333333334332311222222--111111-111111122122223322322233333333333333653333334333333234343233323332344333423333333333343333333312123233313433444441112314411-1111111111111111111-12226343343333333333443333333343333-1243333-33343644444444444444-4454444444444444444444445444344444444444445444444444154444444444433334444454544345344454544444444533333333324555455556455544556222123222355644444444444334333333433332232111111222121112132-111-221-21-11131121-22111122212222243 6545786-G6847776BB899AAEEEBBAAABC989BCDCBBC888A9DFA999A979A9A98997778788878995998887867789C7B6778668678CC955A5H8C986BB7899C9DD8I7c*I1GCH97B9F6BD878898F79O9FAAE57566688856I56965567z55655DAAF9FC6598775 -----1-------------1------------------------------------------------------------------------------------------------------------------------------------------------------4114- * a.80.1 post-AAA+ oligomerization domain-like
[ 298] 44848435544455534544544444444444434443444442444444444444444442448-43 5844434466644444444-444444444444844444444444444444444444442265C45466444444444444E863444433443322-222424444446---------------44344433334444444444454444433444666546454455544444445434434444444254433333552633555344662356244435464556444426666666686666888644724211232223333215164428665552444464444444444454444444444444433444333444248676777777643334444415834746444444443464444424436644434115444664444444444444444446-44444444646474445747776655244644454444444444444444454454423344411---------------22324444445666496666666666669888886867B44344344454633434374444444555333333344444413444464644444344444444444444744444444444422422222224444444755444464434444444944444444444126644632233358335537557775755-55755575755555555553333333355555355555555555333333531333334333333222622222222244646222222222-32--244444444544466666667666668466422222222433393333333633444444444454443446444444222222223---------24-2------241-----34667444544443 22-1113-725222544524444424554444444454442445554544644545554444446644454244644-44444454435544444355546436CA-562868779C5554653A9345CN5-8664445435544453454374562535429742132943623343W44333936C5463464445 ------------------------------------------------------------------------------------------------------------------------------------------------------1-1------------------2--- * c.78.1 Aspartate/ornithine carbamoyltransferase
[ 299] -------------------------------1------------------------------------ --1-----------------------------------1----------1------------------------------------------------------------------------------------------11-------------------------11-------------1--------------------------1-----------------------------------------------------------------1--------------------------------------------------------------------------------------------------1---------1--------------------------------------------------------------------------------------------------------------111---------------------------1-1---------------11-----1----1------------1---------------1---4----1--------------------------------------------1----------11------1-----1---------------------------------------------------------------------------------------------------------1--------------------------1----------------------------------------------1-----1----------------------------------------------------------------- KG8ESOK-pFICLNHFIIEEHHHGHCGHHHJJIIHIHJGIHHJHHIGHHHIFIHDGIGHHGGHEFGHGAFECFGEEGCCFFEDDDFEEFDJIILPHHGFHHHDIHE6IUSgapUVhQPNLPOVQndMpM**b2jd*LOPMcMPfNKRPLLSKHZNSLSTMMKOPHLFLIRYFGNMGMMK*GGGFLlhxwIhWKHKMNLO ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.110.4 SNARE-like
[ 300] 44444444444444444344433433333333444444444444445444554443444443334334 2221423323333334444-43224344444453334344231334533443333333113433433454333333322332-21212333322222--33334222221111111111111132222222222234423---4242222224222222222222222222222221222222223322133444444444444444445444444444443434333334434444444444444444444333443433333344333332333333334333333333333333233433434333434333333333334443444444434342443444434224344455344334444443143231444334233222121212222144443444444-11211112343132233332333332341222222222222222222122212121111111111111111111111111111112313322222222222222222222222222222222222222222222222222222322221212222322222111111111111111222222222212211221111111111-11111111111113111213221112221111111111111111111-12111------22212222221222121-222222222222222222222222222222222222222222322222222212222222222221111111111111211112221212122222222222222222131111111112222212122212212211111222222222232222222221111112-332222-11-----213212-3-113121-11113--221112221221222-2-3 9678B994Q9C888A8797888889799978888888868888888788889887886788788988849989899A7798989A87AB8E7786E7777787FEL79H8JCFDEE9A9EDCEBe*8q8W*L1OHnBDE7JCAFE9CCB9GABF9HCCBCEF9A9C7IAD899B9A899*99AA9QITX8OBA9A9AAA ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.79.3 L30e-like
[ 301] 22233432222322232123333422222322333454444443533322444436344432112123 4563424333332243333-362247333333555534D9265832323332354222227553979453311113111223433432543514331--453445353322222222222222233343323343343233332356556653344222224563344464222322432242232222222233333422232324222222223232222221111113223333332333333222222122111141112222111123412222221111233323332323321111111111111222221222142243555545633333222222223221223333233342332224222444122222222558663224443512222222224-44544633242224423363343465222245333322222222222522224244422322322111111111111-1133323265435766689988AC8889997A9999879BA6A88127777546545484444A644465333333344558A265453444554443444533334446446444333333333333433333333343665555433335465556356555555655552-3554622-22244545444444444444-44444344444444444465554485544444444444444445444444432533333333333223333333444473932656545333333443444444434385666676556677645554343243235333555555544552223233222222223724455441311111111211111-11111111111111111-123133222224443 1111443-522186A87696969BAB7888A8978776567568876768899967777686748345143264442222344555322AB9746974956A332313D7K789D5D675657ACC4D6NxB-BAH5335848A838455B44D7A96CBJT39AB3343644753333I33333BADM9KM66A8EG5 -----------------------2------------------------------------------------------------------------------------------------------------------------------------------------------- * d.115.1 YrdC/RibB
[ 302] 2212137777777777248373677777727766666676666666677566661111112668-166 2236938544448388888-8822897777788888788839A832223111333223--88B8AA9999811111111226622213772726671113423383413111111111111112782732322776777732431778788787776766663779887766666666666666277111384555554444455445534444545888831266666684333333333333333444431111121111111661111111111211111111112111111111111111111211116111111111287787777777777677777788721116677789772168774221662213444111116886622388888777777777772C7677B77282-888888988899674329988888A897777777732226838--1-------111111111111111----13A33333335999A999888899A98888789994444243374E7448A838344734449422433334434871662626666666626667676C722222626211111111111111-121122123225384336132443333644333443434A41-1247211111264336232222222222-22222222222222222227774477466666666666666664222222221932233333333221511111123162736221212111111111222222223333888877887888848881111111112333533333658551144444222222222634488771112112151111111-111111111111111111111166111112222 1111123-844122522223322232223222332323222322232423333424323232324223222322324222333423422362242H555223247311614142144322213287282Hb6-5293221323612212232243542513323131222622345445a4665475593842535365 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.90.1 Tetrapyrrole methylase
[ 303] -------------------------------------------------------------------- 9AK-------------------------------------------11----111-21--11-----11-2------------64356GHFC-F13---4G1C7J9O7C--------------25257664468611111---2-5934553--33333533342C3482-4-----4-----2211--21413333333323333232222313314223142------8312211122222222212222-----------------------------------------------------------------------6116-------1-1-1222--------1-13211633224-2-----42F3DH44B21111AFLNRE7DKKHEE44454553446-MQJFOMLJ6A7-F99GDCCDDD798G588656555463344444444898865B711--1---22--1-221121113311-1-2218748866ACKKKKAA7666DDHGBBBB9DHCGBEDL-4DEF7BC9BME8796CGF8FBG8A11111119698AE848256955AB6631866778B78AA9BC61A921113333223232233338544B8D886LEBOBID4FCEEEJDLIFFHKDJOJNH--1B549------B6887D8ABBCABBDAA-8BBA9BCA7B9CAAAAAABEED993479858999999769688B96875882-788878876777--26343336878FAF761111111--------777774C332C9EFDGCDEGFAEDCACEF1111111119356A66666BEA9AGJA8C8879A654543B7CC36EE11121222---------------------------------111117D84 -1-----------1----1-----------------------------1------------------------------------------------------------------1-----1-----11121-11-----------------------6----9---------2-----------4--9--1--7---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.225.1 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
[ 304] 11112222333334221321122242221242231111111112222121423232222223322-22 2432923322212344434-34114432333344444585265794332222876322116452557C6633222333334351111133331223---1322144414--------------122222212233355332224365553342244222222333444542322222322223431122223544444444444444445556644444434555555554243333333333333333333534465233235433454443324545554545222222222222223333333333323333442333433322222222232332442222322344221133112123112221212423333711111121331112111111111111112-54244244354122233423322334241113222221222222222133234331111111111111111111111111111114333312212222222311112222111111223222112112242213212311211112111111111221222221211211212211323232233653656112111211111111111111111114112213231233123333331333232222311-1311111-11132111232222222222-222222222222322222223243113122222122221212221222222112223222222221112111115444233221111111111111312222212111344334222332322222211111111111111222221312222222222221111112122212311211111112----1---1--11----111--11112311222222422 4234779-C66254A5455546555574455655555556555555675565854465655556544534754346636544445455545445469784354B881E88POUJOPVKGIDGLIlbFjJ**b5eLqGJJCOGHPECJHFDMGCkGHKKKCLP9FGACaADaCED84798f98678IHJU7LE77C9A95 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.52.1 NAD kinase/diacylglycerol kinase-like
[ 305] 22-1--243333333211111222211121231211111111111111122111-----------111 46D5522422332384566-64229F66666788788EIF28385231144274422211355237D5453111111111215211112321--111---11214423222121222-11111121122111111655332211523442242211111211121344531211111211114442211151133333433233334431422133332333222222114711111111111111111111412122121111222331111242223332322122111111111112322322232232122331222311121111111121121111---11211211422211111222423121171365571111123LLM224E6AF44455454243719CBA676D5B81C44A55568765L91724655455556656666668442322211111122111111111111111111111235D11BHGBBC7BBBD68899AAHC99894ABEE8EH8153434675586B3C8551112112111111112214424342122112111112121112145445824111111111111111111111211122223232-131411111-111111-11-1-2-111332------1133--2-122-111---------------------113133-12---1-1---1-1-11-6----------11111111111----11111333325527---1--------21-44444121221454643968345642A8B1111111113111-------1---1132222111----111111113211111111111----1-111111111111111111111121121113211 1121432-K333--4KMULKMKHPMPSGGCGEFEDGGIJJKIICCBNHGZPdlrIHHE6DAAA86355662793A75255455577244EPAM99B564C46722314F4i8AB4973222343A7483Ku9-96B33337425424242442936A695775B48CD6DIDFC23554n6547BIKHOO9F4333455 ---------------------------------------1--------1------------------------------------------------------------1------------------------------------------------------------1---- * c.117.1 Amidase signature (AS) enzymes
[ 306] ----------------------------11---------------1--1---1--------------- -1-------------------------------111----------------1-1---------------------------------------112-------1---1-------------------------1----------1-------1------------1-1------------------------------------1-------------------------------------------------------------------------------1--------------------------1---------13---------------------------1--111-----------------1----1---------1------------------------------------------------------------------1-1--------1---------------------------------------------------1-----11---------------1----------------------------------11---------1-----1----1-----------------------------------------------111---------------------------------------------------------------1-1----------------1-----------------------------------------------11---------1------------2---------------------------------1----------------------11----------------------1---------------1-----------1- ----1---2-31-13-2-221421-112121113113-113-12331--111111-3--1--2--11---1-----1--1------1--3-222--------111---3-*******hilkkwj**c*m***1***cieh*jn**UmjgXsbc*n*roqESRaeXPNjOO***N7-2---2-21-2334-431-3-113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.123.1 Nuclear receptor ligand-binding domain
[ 307] -----------------1-----122223323111--1111112222222322--------211--11 4362422233323233378-7533357777725656434432223335344434433433434454334534444455323322233244543544411444644454555445453344444533433333333333342224233333333333333343453345343332333332333222222223333333334333333344443333333324334444443454444444444444443333445333334445544334334343333333333333333333333333333333433333333333333323353555454434343444333333222432244423242223223222526344344534344454535555544444444444-55356345453335544443434433544443435445333333333344333332223222211213333334334444222223433366654677667555554454555533775864533887353333433563532344445444444333554333243322311113223244222222277242222222222222321222221222445556566555566555655555655556562-4776621122255567555555555555-5535555555555555555555555556565555555555555566566655255555555555522765555544445555655544455533H555444354344355555555656656655553343433434655655555555654344443333333333334445444443433332322213-333333333334334355422222222224574 24233321A33333332312254432112111142221213312224541522443733363152221-23213413332111122121223232312211522232273DE9BBK89588879WN8C7U*B1F7I8786D86C795757I45CBCB7H37J376G233259EA43232G32454524934354A5262 ---11--------------1-1-------------111-2---------------------------------------------------------------1----------------------------------------------------------1-------211-- * e.11.1 Type II DNA topoisomerase
[ 308] 112-1-212222232121111-1-93323174333-13122123314324666-11---112212--- 2-122237556554444AA-AE22F3AAAAA9C789455622452446611143B234--43614142753465545511314-2122-11211-1--1-1232212311111111-1111111211121-11-122273--136-4353322-111111-112214121---111--11---32221-12324444436424454443122224462211112522224123---1-1-12---12132-185636551235772245422312678-------21121222221112---------1---211222222213416555658655535773112422444231-2262-32212523323412-5225-----453365144332322222221224-37414A54746-2112325731457A-415155444113--------311-1334------------------------------2411--1--14333332222255233222133343456127833337744134131633231-1-22222-2213311412122142334-22112213-345314512131122222131232322313-133511311121213-3221-1211122211231---2215------2222----11---111--1----1---11-1-----1222-----1111111111111111-------1--2-------------1------2233412------1--1111--1--------221444456154431-212323---------311121111112-1121--------------2344--21----------334441--112-1------2-11111113-1111113542 7777GD9-TCABA9A7BA97BA9DABCCC8A9AEBBAA9BC8B9CAAB8C9EHJCAB86A9A656884-661877542356887782425G7B64D5536565PIL2EGHDFNJMDaNBCDBDJRWGP7u*K1VGjADAHCDADB9D88AHE8XDOEAJ6GiK95B4XBCfKQAA5DC8*B87BEAEISBHD87FIDGD ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.23.2 Diol dehydratase, gamma subunit
[ 309] -------211111132-------------------1--------------------------1-1--- ------------------------------------------------------------------------------------------1---1--------------------------------------------------2--------------------111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----1------------------------------------------------------1----1----------------------111------------------------------------------------------------------1-----------1------------------------------------------11----2-----------------1------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------111-111--1--------------------------------------------------------------------------------------------------------------------- 4388JP9-6224ACb58AAT5777765A8GD9B5676777898887LR97AFFYBCFUACBA443555255546467456555553FDD*CD8AALD9AVAE5FM*3G*BMyidljXTVUVPaS**PyQ**p3ui*QXTPjRVrUJYVMOdMNzOeSUaCFOBFDjIRFJNDSMC3BB8Y534I9PLKQBFE8G****6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.34.13 Chromo domain-like
[ 310] ----------1--1---1-----1------111-1---------1----------1------------ 222-31-----1-111111-12--1211111113332334---3-1--121--1------12-44-1---1----111-5P8422--11121-2-----232--23322---------------22242323212-1111---4-6343333112232411133326551-1-----1----3A11112-223555554563665566625534368222342631111214----------------111-121---3-3-13411-11-1--------------11---------------------------------13B3572222222223222212322543121132BB12131312122311111-523211111348773345463644434344343-5375463455315445445434343522212-3133-11222222224332343611--------11111111111111111121224414664244444442334336533333343543441133434332252363443222223222222222242434512223435333112122131232234433214111111121111111112112122442221131222332314333342311442--111111--11133443232222222222-223222222222212222322245343222211211122222232222222--333333332333---12212255552224322222232121222211111112223233333334234332444111111111-3443222224242222332333342222--2-3311331111111121--------------------------11111111112-42 -11-FD4-31126756AA88AB787874525349564434355433B969BCDG5AC54899213231-22214222112211111111DMIADTD566DESGTMW-12O*dWUjhWFBD8GJETaEZAh*O2THdEDHDMETMK5LCFCZCCh7iSJM79Q8DHF1SDFNC9A3-DA3g332K9hzz*9ih-2HKGK3 -----1----------------------------------------------------------------------------------------------------------------------------------------------------------------1----1--- * b.52.1 Barwin-like endoglucanases
[ 311] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3----------------1---9--------1------1--------------------------------------------------5----------------------------------------------------------------------4----------------6------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------3-----------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------- AB-111h-C-12--3--------------------1------------------------1----------------------------------------------58C*******nlffr*h**c*t***2***Zreq*q***PwpZW*cM*o*yvvBIhBMRA-F24O7AMM28-4L29443123--2--119129 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.24.1 TNF receptor-like
[ 312] 33312-888888998A--22111-2---1---------------1--1--4----------1----11 3FD25-1-111---11111-13--571111144555137A342421---11-2121----11C-44D655------111-2-53-24---1-----1---113AB-8----------2-------1-1-111-5-899893235C-3434412311-------22-6365------------B774179168122222212-11111214---12111534224------87--------------------2---11----1-----------------------1----1---------------------1---1111-8L7AH89898BA7A955665122B3732458C9HFAJII4HED87793--F565443111--36PST6358A8F81211-11-111-KIPHJNJN8D41733622A8728FC635-BA1454488966666666C4431KB3------------------------------3782-8B968EIIIHE52221IIJF222213C8JJHJ7-5BBAB7934I28CF266B3493C4--------117AL6BJ8E7HD6LLFGF1DIFBGDE8D4444B77B6-------------------322--22GA2CAA63B579EBCCBC7BAA6B9667II---1255-------1--21-3332322232-3333322323324332331221-------------1--1-1--81--1112--113123312222---4--------121D46---------------1112114-2186BACB47E9BA7A76534---------452478998865ADE33565663331111--G55544331--11111531------------------1------BG4EF7AA9A27-- ---1321-711-22-323221312322333333432132231233324131534122122322-12-1-1-112-1-1-2-111--2-12522216-11-143312-389I36559P85544A4CH475Ei8-76D2533924B435744F52F4825A4AO2D85EFCECN5C6-23-D1--33BCEF2I94353132 ------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------ * d.133.1 Molybdenum cofactor-binding domain
[ 313] ---1111--------3----1---1--54-113-1---2111-2L-1221C81-1--A1-5-1---I5 6Je15111111--124444-45--75444442955523A7293C531-1---223312--143-645329---------------3--WTQ7-H-----17-42EH82A-----------------3141---5-48858--182146549113--1122--231B59C8-1-----1----43413411--2-----------------11-1-12-111--1----1-41--------------------------1----------------111-----111-------1-1-2--------------1---------41115232424614-1-22----415----11--132-3--41---2---71E2--1-----338342--22-32----------1-32223142321-1---2-1111-----141-211113--22222222-551-11-------------------------------1--1--111-6344451333366673344-4659-11-1---23-1--2-2423--624111--------1-3-1179-73----12----7D634AG1-4447Fb2D--11-1111-1---------1---211---312-15---21-1-2-----11-2-22---31-2------1--1--------------1----1--1---------------1-----1---1---1111-----11----111111111112---2---------2-4-----1---------------------4166664443334423324---------1---1----------5323433323------139978ED11121222421------------------1------43344233232I12 -121526-2273--2334-1421522---------1-212112-22111213452232----1--1--1-111--22-112---11311--2313411---1----14***IIKTIJCDBABGCkRDMFe*P7SFfEG8DKCIRC9GDDDPDDQGTILNFGIlnQDFODASDzk86764C2334579BH-DC5288477 -----1-------------------------------------------------------------------------------------------------------------------------1------------------------------------------5---- * b.68.9 NHL repeat
[ 314] -----------------------311111-11-----------1--1--------------------- --------------1------------11-1-------------------------------------------------------------------------1-------------------------------------------1----------------------------------------------------------------------------------1----------------------------------------------2-----------------------------------------------1--------------------1-------------------------------------------------------------------------------1-------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1---11--1----1---------------------------------------1------------------------------------------------------------------------------------1--------------------------------------------------------- 1-1111------134TRPIyxmdm*luOOGNCIMIGKNIKEHH9EDNKj*zk*ubhPLLLKPDHUFGG6JFKWJTLNHQOGLRTIU5AA5ICR8MJQILG75MCI9125B*DCBBYHQKSKC7B*XRyP**j3kXmjNLMNBNYAINJ97eKQ*IBHVN9CK58M44B8D635E21111-----16ALGKC4-22212- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.80.1 AN1-like Zinc finger
[ 315] 55324622222233435333433122225232111111111111111111321122253332112-11 333-422222112122244-6122334444433323324526431223122221131311343232257411111111321122121144441344---4425352254232222323333331111211121212223311142523422311113222112222323711112121111233244222333555454754555565453333666534434333343353244444444444444222324522332122312222322111133355543335455445545444455555555566455655555553444242222222526433336745332452432222222112233443323241222-----225555223224222222222223-45535544551-4333344334432322334333333332222222214412222-----------------------------122221222114554445444344445555155443433-144422222223242111211132111111123312142434232245222-334434463343335143222422222232333333322332338623112134335465338433548B55C61-2211122-22264445546445655544-44655554554543464454545533455555655565656556344444421454555535555111-222222222212223333333333334432222224211432222212122222322254555555415766555555746622111111111111--2433333353312211232----2-212232122222212123335433454531412 22--325-E3573545943aLYDdecTEDCE8B7443444365B9963YvJOWs99LQ573823223315224112222322222333468394341211363332-459FDKEGG79559566HH8A6Y*C1D8B6956C44B635663A67E8776E27A9BE36S6587886333161113175BC56423A6842 ---------------------------------------1----------------------------------------------------------------------------------------------------------------------------1-----1---- * c.56.2 Purine and uridine phosphorylases
[ 316] 111111---------12-1111242--2113-212--------1----11---111222231--1111 4572732422223222222-23222222222232223833622352352337384344115452823667212223443333212212557714441113433245442111111121111113211323432342222335632C655444223355564434243333655545555555634112233356787997867778B753564677833437224444446645555555755557434453532232223334422243322343233224463344111112113227766546554655377443877234357444444464654775876636255673466644334321112222414944314326437676474634633333333337-66465D548772655B545646744B4343273422252555555554B9455352222222222111122111111111111139B5624423622352462222554423233227324252356424B85A453422243428455754434252724476424384966883436635428335345364121215134212111111122233534442458244428EJ9555955738473351-3244611111137223834885494A47194483775459A635445776433339442424336256644655443343815333433336351152444437789334CA43454445454548474685723123256896A69388AA3BAB2222222223553546476533554334433333743522944444452222232332212-1-----1-1-111----11---22224233222522 3113222-622-543233343431342332334333144444433342234243332321313333333333342332333333333332733224333334333112D37342253334245483352CJ5-4584144324523544543344544932227342433645734564X3446698GM3CC6655535 --1------1-----1---------1---1----------1-11111----111-----1-----------------1------1---1--------1-1------1-1--111-21--11-1------------1-1-111111121------111-----1------------ * b.87.1 LexA/Signal peptidase
[ 317] ------------------------11111---111---11111-1111-1-11-------------11 1212211111121111111-11111111111111111111-11222111111212112111211111---422221111111111111111111112--11-12211212111111211222222111121122111111111111111111111121111111121111111111111111111111212211111111111111111122221121111221322222112111111121111111111132122221121111122112112111---11111--111111111111111111111111111---111111133222222212111231111111112111133111211111111211212211111111111111111111111111111111-111111111111111111111111121112111111-111111111111111111111---------1122111111111212211111111111211-1211111111111111112111111111111111111111111111111111111111111111211111111111111111111211111111111111111111111111111111111111111111111111111111111111112--11111------11111111221111111-2111111111211111111111111111111111111111111111111111-111111111111--11111111111111111111111111-211111111111111111111111111111111111111111111111111111111222222212222221-1322222211111111121212-1-212121112212111111112111212231211 12-1674-3343A8B445565555455554545564566666644467554636445557783423321322323221223333334348A8497H7646363DDB-CWImmcZrvsUJLMVcQ*qLtO**n3*b*LTROgTVeRKWOSKYMM*TSVWWFKIBEEFBG99N55J9334AI39563W***4*X44B97B6 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.15.2 CAD & PB1 domains
[ 318] 112-2322222222222234433122211122--2112111111121122111121233311112--1 1461612244411222211-11112311111-33332433141421312111233111--32224145776111112111932112111122-111---1344473341---------------4111122112257779111529377776353322232236238785121111131111222--2212333333333333333331322123332224221------25--------------------112-22-11112211221-1111221111111121122222222222122211111111132211-2221233221111122131321111116131-433-1441--4222---11113315411322222327673333333333333333334-554454447532744466655644353334554444454--------222--3323333333322333333333333333323324444-35544777676333334444565435845454522776344448454644354343531111111333334273244533443332332232362443483252221211111112111111112112333344455333776666666666686686653-4333422-22234353334446476654-444655656546644444633333335434344444445443434445544323555455554442234111113533535332223432222233331111111111338888875664444355532222322233334333335455356555554443333223144545522222222523----------1---------1----3333333333-622 3322B98-C53-565555555545445545555555555545555545465555455555554442222421444222222555453335845536333332377C-7A9ONWEEQC99688C8KT6MA**C-HDQA877E9BDC7B966B88GAD99FADHGECA7R8CFEJEB3475*33359GEQQ5N68987799 -------1--------1--1---------------11--------------------------------------------------------------------------------------------------------------1--1-1-------1---------1---- * d.43.2 Band 7/SPFH domain
[ 319] -------11111111-1------1-11-----11111111111111111111111121111------- 1231112233121222233-33222433333233332222121221111111222112--112134222211111111--31211111---------------2--1111-11-1--------P11111111211333331112111111111111111111111122111111111111113222222--21111111113111211122222111221421111111141-11111212111121-11-1------11---11-------111111-------111------------------------1--111-----3121-------2-2122221111-11-322112211111311113---1311222211121322222222222233333333334-2222222334212443222222333232122211112231111111111121121---11111---------------------11111222222333333123323332333314322222211222113222122531111111111111121111111121111111111111111111111333323221-111-------1-1-----11111111---1111-------------------------1111--------11------------------------------------1122---------1-------3----------------------------------11122---------------111111111111222222231221111111--------1----------------1-1--1------11131111111---1--------------------------------12--12111111- ---1CC--321-11333F74554745454445734334432466449659656855642322813122133321211-113111233232D4334611222314J7-49j*ndYWgoPQNLRvX**O*M**p9nf*OSSIjOasZNVVOMdOJ*SYaXaZcPK*U*8IELODMPL2621G21143J7GS8WA6259761 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------7---- * d.154.1 DmpA/ArgJ-like
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mE6AA969889B9AE688BGAAE78BC5D99F699A7797*756978AEF7AB88BB97A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.51.1 Class II aaRS ABD-related
[ 321] 22656642444444446466464E444424444424444444466466242-25AAAAAAA444A-66 24647514333--122233-3333273333323555559D466536354332553544--54B264BA86A2222222----4444444441-423-222222222242222222222222225444444444454445423-45224322322--------32324422------------22233--24222222222222222222233222222225222------32233333333333333322222----------------------------------------------------------------------34-1-------2-2-2---1-1--11-2--236612B--355-------26242242222223E6B42C4486822222222222-88A669666842422232664446482224442222849--------422-4844222222222222222322222222222222242224KCCI64444464444448B44442444E4KGF2432278468C5468A2364222462333333446C442QOC44B7-6A8841868372A24226244K8--222223221--111111144664225422422224444445444444444444442222544------74444546669699966-66667996666966758775565444554445455555555454445444542444444444444222222222222262464222222-222122222222224222246666242224442222222222222224444444444444444444444442222227-442222--------1---------------------------2---2-2---4322 54--555-B327444666567777775665666666766646666658768758446666664222221222233221222212232444746544444447654O-546CBG8B895555776DC5D4Jz91A4B46449558945665765C4857C8CL56556C5BA99766442T22234A6DN6A64556555 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.23.4 Succinyl-CoA synthetase domains
[ 322] -------------------------------------------------------------------- ---------------------------------------1---------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------1--1-------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------- ----99G-----224-------------1--1-----------------1----11------1--------------------------------------------L13p******ojgcloj**e*i***F***Zogh*ct*lZohlW*cV*l*txrPi*bSQROvGOeMZVL-11181111131-2-33--11112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.11.2 Second domain of FERM
[ 323] ---1------11-1--2--1----51121-52--122-1--12----11-11-1111-11-1111-12 2121B21222211334433-35334633333354544486162312221111222221--432-4424444--11-----1--113111111---1---16221312-11-------1-----2---------1-13224---2-IAHFGC9FE9ACCCCCD9ABEACFG12221113122123211---2343434443436344343333334342324243------7322222223222222222233----1--1--1--33--------1--21-1------------------------------1---------1---1-------1--11---1111-1-----3-3211----11-------4145335-----5466722132-3211111111111-34635525212-344354444354482433121-122652222222244421223--11----------11--11--------11-6611243423335334233355333333334644364-13323422136223-441233371--------22-3131--1-1--111---1-11111-2121229--1--11222222-1-------3--2356221222112423344423-34313112126---11-2------12-11111111111111-111111111111111111213222211112121111211111111111111--133323343222---------222234423---------------2222221-112-223221124113231211---------2114111112222211212121111121--22112233----------1--------------1------------2-------4312 A756EC9-Q8A5AA6758867569C785454667676656845647A779767E579579695797896977A67673776AA97A4769D75C48747536458688HCnUWJKfIEHDLCFEPR9XCz*O-XMQEEC7MEKZF9LEGBIBAKHUDEWDIICyQm8ECEEXkIFEIG9*8C695TBAJ5D8C5FA8BD -----3-----1-----------------------------------------------------------------------1-----------------------------------------1------------1------------------------------------ * a.1.1 Globin-like
[ 324] 11---1--1111111-1-1-11-4822512A42112211212111241111331--1-1----11-22 3-22n428AAA233bvpII-Im44n*JIJJJcjnsnbl*u2*B*YLB38A92GGD457--DFM2UEPYHRC-------1---F-----221--1-----14-1-52413--------------------------44474---3D21--113----------1--173B-------------5221111-2-8555554541345354716658444313563222222-6D3333333333333335335822--11-----111-12-11------3331------222223222221111111111111112----11-112-------1-1---1----------121---122----1----1----3-28444-----E3HDR2223115233232222226-B89CA89C9K7-sNOSGC7FFG66B923-13F23232443-333333122-4--2------------------1---------1117Q2-542-5BHIHHE88885BBB9CCBB37GCV6765-14463251184137-16--6261------------211--------1------111----1-1--AA---1-1--------2--------1---1111-31121111-1112-1-11121---1-2---1--1------2595-543333333333-33333333333333333327CA56352111-1111111111-182243332--322222212222---------1----1113211--2---------668663D111L7CC7C7D9I5BI963CCD----------232----1-2-1--654111111111311---11--------------1------1--2----------1---------------1-3 1-11-12-1--1-22667174648699----22-111313233312236435C7551247566-1223-2-2-23---1-433226--1-636-12--11-21-152-246533524542132244172BK5252834144143233-417225263571262424432932321---15--1--831735--421111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.1.16 Bacterial luciferase-like
[ 325] ---------------1-------------1----------------2-1--11-------------33 3773433333333344544-44335544444544444445366334343333434333334436667444333333333333543444333333331--3333344444--------------2333333333346336633654333366333333333333333663333333333333345434--3344444444744444444444444444444444444444433444444444444444444443333333333333333333333333536333333363333333333333336333333333333333333373363333333363639933333334343343336333474474433334333333333333-4333333633333333333333-33333333363333333333333333433333333334333333333333333363363333333---3----3---213333333333333333444444333334433444434433333333443333333534334334334333333333337333393333333333333774333433445554433333343344333333333363367443333333333333333333333333333333-333663--33333333333336333633-333333633336333333333333333343333333333333334443333333333333333333333444443333733333333333333333333333333343333333333333333333333433333333333333333333333333333333333333333333333333333336---33-333333333333333333333433333334433 3333334-C6R34433333433363623333333333323313344313333332333333333333333663333665633333333333334453334354438-3589NcHHHQ47D8797B76B6Q*8-B8H5847B858576875848C87977-9R34654T647ILC33333*64333E8EO4GC169334F ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.130.1 S-adenosylmethionine synthetase
[ 326] 21-1--1111111111-111111111111111121111111111111111111111-121-1111-11 1121222222222222211-1211321111122121223212221222222122222211222222223232222222211211211111211111-11112212312221111111111111111121111211122111111121111111111111112111111111111111211111111111-111222222221222222111111222111111111111111111111111111111114112------1---11-------11-1211111111111122121212111111111111111111111111111311111111111111111111111-11111122112212111211-11114111111111212222222221111111111111-11111211111-1111111111111111111111111211111111111111112-----------8-----------------1111112222232222232222222222222222222221223222222222222222222222443323322222212512311111221-32312121211112222111111111221112111112111211332222232233333332333333234344112232312111133323343333333333-3333333333333233332344333333233333333333333333233332-2222222122221122111111111233122222221221122222222222222122233222222222232222222212233344322323434432442442223333112111111111111111211----------------1----------1--1-1111211 8846B58-YEC4A6E55678B9A96ACBB99999A97878578AA97993B9A8AAA7796688767638A78A588378877877AA9AD85A88CAAA8A94694CI2hNRLPHKCF9ALGGkZ8dC**J4ZRYD7CBMFBGG8FFCEKBARBEGEKJXZkGCGDXOMyGPJE78CD*FCD9DCCFN9LE79AEGB6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.258.1 Chorismate synthase, AroC
[ 327] -----1-----------------35475344411122222222443443332213333333-337211 1111111111111111111-11111111111111111111111211111111111111112111111221112221111111111111222112111--1111111111---------------11111112111222114441111111111122111111111111111111111111111111111111112122121122211211111111111121111111111111111111111111-11111111111111111111112111111111111-1111122222222222111111111111111111111111111111111111111111111121111121111111111111111111412-111111111112111111112111111111111-11111111121133322222222311111111111111111111111111112-11111111111111111111111111111111111111111111111111111111111111221111112111111211112111111111111111111111111111311111111111111212112111112111111111111111111111111112221112112111111111311222111111121-1111111111111111111111111111-11111111111111111112121111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111112111111111111111--1111111111111111111----1-1111111111-11111---11111111111111 66337774RYD89874855786775785645555655545455555557776A8566365554335444445444453453333334557B788785444554AAC35WWfTXYUUFGILNMMYQVGyK**P-iUyHIIHYJKbQ9GIPGREBYIUFMTGHpEc*DEIEGmEIbF8BCA*99958bIWc5Q*78EDHDH ------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------ * c.32.1 Tubulin nucleotide-binding domain-like
[ 328] ------1-11-11111-------11115-A1---222------BX11P12baB----2-----11--- 112-1----------------------------111-------1--1-1---------------11-112---------------1--1151-------19522QA436------------------------1-----1---2---------1-----------------------------1--------------------1----1-----1---------75721-2-------------------------------11----------1--------------------------------------------------------1112-4----1311-1--1--111111-1----------1--1-------------------------------------------------------------------------------------------------------------------------1---------------------1---------------1------------------------------------3-------------1--------1---31-1------------------------1-----1-41-21-1-11-2--32--12-4--2---1----------3----------------------------------1111------11-111--1--1----------------------------1---------2-3----------------------------1--------1---------------------------11--1---------------------------------1---------------------------1-12------8-1 ------1------1-----1---------------------------------1---------------------------------------1-------------2-1py*m**rcefeV*h**i*k***9***XwlS*gi*hTpsfQ*TO*e*YgiFMOUJIDNWJJSJaHA--------1--------------- -----1-------------------------------1----------------------------------------------------------------------------------------------------------------------------------------- * b.1.3 PKD domain
[ 329] 11-2-22322222222-22222213222112111111111112111111122112222222112--22 2592532222223342222-2222442222242222559846755342222255542222338242555423---233222364334333332333---34558665431111111-1111113565455455446663322253797766445555555555345775455655555555534423113433444444443444434554435343343432222222235233333434433344222332--2--22-2-3322--21-3112332222222333222222222222222222222222223332222212-933333333-3-342232222-3-223-33333333-1323322122433533611111454445465433433443444443135745A37444223335446333345233213111112244444444355435342233222222--2333223222222--112253333222245566478687664787882567635542433634323344343435522253222222222444343123111121222111121211144447B124333443333352454444433344235445648345345565575555555565443-145332-----63334434444444444-444444444444444444444644353333333333333333344444444323333333333342234333335555434653334333443422233333333333645555565554344765522222222223334333335353333333333333333222-333333--------1---------------------------11-12313232424 21--674-721166475673544766667555567775552555456566755665755757555456363355534-445665566877F658498775668577-974IABAE8AD8C647B99A8BKhB-99879B763593457A5789AC6CB656438573979E24D45773c34346789B5B965AB784 -------------------3-----------------------------------------------------------------------------------------------------2----------------------------------------------------- * d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
[ 330] -------------------------------------------------------------------- 79D11------------11-1---1-111111-----11114233--11----1------1-1121-11141-----------41322GGJ8-B661--AHD8BHSE5D11111111111111133556333643---------1411--1112----1-1-1--22125-1-----1----1-1----6112223234333334333112212333112121122222221111111111111111---112---------------------------------------------------------------------14133222222221213222333112--121112212111113211116863277772111147CDA6758999B55555554556-76A66A795A638667797A9866665A78A8BABC8AA44444444A7777DBA1111111111111111111111111111117576458858LGGFHJDCDDDFFIGGGGG8FJCD9CB824868DA8978987G389FA6588523111114467AN88E377D639D9894FAI9BAA6C78B7HX84955434444452322222223543444CC37BDA5976CC9B99CEDABBAAGBB9B1-56A5811-11167434555777577786-775676666777656555577643753474555455455555574346666227B9ABBA9ACBA112633333766655H7A4443443222134335677656698BAEEFEFDEHIFFGHFBCC3333333339DDHF77777KKECC8898A8789944441246DD99A92222222263--------------------------1-121111114227 -1-------------111-111111111111-111-11111111111111112111111111112111-12112122-211-121211112212121---1-1-1---3------------------1--------------1---------------1--1-1-1-------3--------2-----11----4---5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.79.7 OmpA-like
[ 331] -----111-------------1-24222-223-------1--122--2--311--1-1-----1---- 22525---------32222-22--2822222252224444-127-1------232--1--323-313232---------------2----11-------123224-422--------------3--22231-3-3-22-1-----521---2--22-12-2322-3--23--------------1-----22---------1------13---1--1-23----------32---1--1-11---11-1---2----------11-----1----------1--1-----------1--1111111111111-11---111--4----------2-2-------------2----432---1--1--21---3-94222-1--13353322-22728------------871434-3482-444433743444212232241222335--------2---2--1------------11111-111-1111----22-2-211--645666233334431333333362-533-2433342----312--42--2315-------412123-243--3---3-----12214224113113212-1------------------------13254324212444344426664351-413----222------22223422443232232-42222222224222222223332312-3222222223232322322-2222--144444434444---411-114544--323---------------4333311---4511213331389833343422222222--11143333352661232522---2222--2-221122---------------------1------1---1---------2---22-1 31-1236-A3A44387AHDAA99B8BB5568556658766666685969AFGDRCCD979995122131211333154262332221-1LBGA9562233535546-4K5uHG9DASA98CFGCJJASB**S3UFT9CACIBCGG7EAD8DBAYCD8A8Jgp4DQ*aFLMgLKD339B7k6B548****C**AJFA9E5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.93.1 Heme-dependent peroxidases
[ 332] ---------------1------------------------------------------------1--- --2-1----------------------------111--------------------------------1------------------------------1--------------------------------1----------1----------------------------------------1--------------------------------------1----------------------------------------------------------111--------------------------------------1---------------------1-----------------------------------------------------------------------1---------------------------1------------------------------------------------------------------------1-------------------------------1---1--------------------------------------------1-1----------------------------------------------------------------------1------1111111111-1111111111111111111-1---------1-1--1-1-1-11--1-1111------------------------12----------------------------------------------------------------------------------------------------------------------------------------1----------- 5445CBD-K882CDDBBDCEDDDECCDDCCBCEDDBDCCCBCCECDDCCCCCDCCEEDDDDDBCDDEE9DDEEEDFHBGHEEEECEECCBMDBFCDCBBC7ADIKH-EA8Ygtj*oyTOOKUWR**QtP**aDrX*NSOPhKVjKHUUQLYOL*RgTWXFHQRJFEBQKKSJUIG6B97F79767WYhrCpI55BDAB4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.118.9 ENTH/VHS domain
[ 333] ---262-1--------61-----3222513-2oL--11--1111113B149232454712211-3-22 5BR---1-1------------------------------1-31421---1-1211--1--223141-2611-111---3212---2-166E9-91-3--38-54A3B47----------------1--12---228FF44-2-4-2111-1122--111-211212-411-1-----2----24112--112-22828BBD3CBDECB-33352CF521221-42446444B-33434213233322-1---5-1-22----1----13-----5221111----211-----------------11-11-1111---11123-1L6111121152631---45-BD443933-3237416111-1113---K2D5231-----1-2312212313412211222223-33133211-1--1111212222-1-22211222122112----------1---32------------11---111----------11221112221111241222122235222-33243223--22222223C1-22-212-1121-1111111--1-332B35323233444123-2252C324433OE--512-1----------------3--11113-4394242255BA661233321434328----411------16-29-4CRT8C99AJ4-L4CGb7EFD4TFWDDCGD8-----5391811121111221112---4----3-DJNJQRLROdJM--14-----2221215---1-21--1111----11111-2-2-2A2222523-12-2-1234--111-11--1113222226512521554553321111--11331144--------1-6----------------------11--2-1133435-341 14--AF8-2--1--212433--12-1112-222-1-2-1-------11----2-223132221-----1--2------------2----1-12113-2---4122--193SJKQQZUJCGABRDaRAUG**j5cR*DKFERCDPHDEG99YCAiEYKJY75E14F522E8AFV651---6--1112135262-312-11 ------1------------------------------------------------1--------1-------------1----------------------------------1--------------------------------------------111-------------- * b.1.14 Invasin/intimin cell-adhesion fragments
[ 334] ---------------1--------1----131---1--1----1-412-422-11131113-----2- 123-4F354451-134612-1511541111113DFC5P562I563732-321888-12--115-4244581-111-2---211-111-2142-1-----154715-24---------------31112122122133321122B1EF84A6B33221111114583BK9C111111111111213112221243534424313971541132233322323143----2-231212122-22222111-12-22-2-211423212212152---1-1322312221211111311111121221122121-211111111125-1------2136231221-------11-2--1--1---2-------1-3131331-----221333211211222222222222-24328923411-1113112125311112112543311112222222212141312------------1----1-------1-1-11111-141271--2--7----3313-2----293--1522336443129H94311312-111122----2-3231-42323121111---1436231316DBPH57-2----1141111--1111111----1413314224-5221557433442353233224---3122-1-11131242723A82366733-6412797233944222224652226543534445354343344443243331-454454444754--P-11111---133711---21--1--1111-11221112215-4554328634636453611111111112233212213437344535332222111--4-22222211111111214------11--1----------1-----3-1-----16-4 --225A6-B2434373255354354452244343132232132222354445735352532222421231131231131143222322235225165623733V54-EF6kPSMSeDIAD8BEFbPDSEy*N2ONV8EHBLJGKD8GBFAM9BWIIEHQBDIJE8U9MFLJ7FD827E5S46444RGNO4QG555E7AA ---1--12------1------4---1---------112-3-1---1-----11----11--11-23--31--1--------31-----1--2-112---2--321----11-1--1----1----11-11-1-----------1-1-1--1-11----4-8---3---4-6522- * d.4.1 His-Me finger endonucleases
[ 335] ------------------------------------------------1-111------1------1- -2--2---------1---------1------------------------11--1-------------2-1-----------------------------12----------------------------------2111------11---------------------21----------------------------------------11------1112-------------------------------------------------------------------------------------------------------213333333-3-----1-----1--------------------------3---------1--1-------------------1-------------211--------------------1-----------------------------------------------------------1-----------1----------1---1-------------2-1--------------------------------------1----------14C----------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------1--------------------11------------------------------1----------------------- -1--21--3111112133352324753112122--2--11----2321122233-22--45412113-1-31--1--1--31121-31113331162311212423-21C*******oihjllm*vo*r***4*h*jpolriowTYondV*mZ*p*ruiR**U*tsZoZc**QZ812-3A411112212342--22363 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1- * b.68.5 YWTD domain
[ 336] -1----1123334232-2-------11-----------------------241--1-----111--3- 74J-1--------112222-23--252222214222158411-7361112211-2111--211-2-6351----------2-1-----AAiX-61-1--36136M3T-G----------------------1---1--21-1-61812222111---113121--74593----1-------2111-1----1-----111-11-11121---1111----111-----111-11111111111111-1111--1----2-------------------------------------------1--------------------1-2---11-1-121----222-----511-------------------3-A5447----131E88---1211122222221223-5443434B573-677354577668211231122122213222222223114-11--------1----1-----111-11-----2-4543-31-514434235664224765542363C235---664425226341A91161---1----------1-2-131---1--13----1-1---1--311258----1--------------------------1516929219333355454442533434---1-11-1-----112-22------------------------------34413-1111111111111111113---------222222212222---311111----133331111-1------11122322-211-1422221256232321445----------11--222222231144A9D997883222--11221122-11-----2------------------------------1-------B-1 7446B771K56497BGHHAEBA9LIK8BA9BAA785A785668A58FCAGKMKH78GBA6698738963869247652565A9645523AJBHBFE8ABAA8A6ED-9PBrNDHFGFOKKAEBEJMHUJd*E-MGZGKKRINFE9GGKAICNIIGKEECCBGEPDB9aFMMCHFF6DIAo776ACSJIOAUF8EPFJQA ---1---------------------------------1---------------------------1--1---------------------------------------------------------------------------------------------------------- * b.68.6 Calcium-dependent phosphotriesterase
[ 337] 22222222222222222222222133343234221112122221121221121222222222213122 3332222233222222222-22222222222222222222233423332222333232223323222232222222222232331323555434442--333333334311111111111111233333333333222222222222221122222212111222233222223222223223333333233344444455455545543554445533342333333332433333333333333343342333322323333322333333333333333333333333333333333333333333333333333333333445333333333342223333443332243422464344333443233322333323333333332233323333333333333-33333333433233333333333323333333333333333333333333333332212222212332222222222222222223433344344555644544444444444444544546544444444445554443353332444444444233443334241222322222333333343444433352222222222222222222222222334445453444444444445555454554552-4444522222253444444444444444-44344444444444444444454444444444444444444444444444442444444444444114444444444444453434444545545553444444444444555546444444444443433333344444444444444544444444444444432413233332222222221232233-113111111113111122244344444441313 4444565-E5544554444445544344444443434444344444443455554444444455555555545555544555555545547443444444444555449779G78875664786CB5C5Jp9-AAF5667D569836576867D487685BF56565A56935557667l76667759D4A77776657 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.15.10 TGS-like
[ 338] -----1------------1--------1------4--------61--4-4IBF------1-------- --1-3-------1-31145-41223143334311213112-11221121212111121111131312444-1111111----------22---1------3-22G123---------3----------1------22212---21313911----1-----1-2-1454----------------1111--1-22221212311332112552-112---72321--1--73---------------1--1-21-11111-1-1111---------------1---------------------1-------11--------41-55222222222111--211--22--1-----1-2--1--111-1-131--2331-----332122--331-1------------24533532-22-2224115264412421-211222221-1111111131122254-------1-----------1----------122-21111-423213-111122311111125431112----22-2--31212-212--311-11--1-1----111-4---21173-11-11-111313--1-11-2112--------------1--3-1--1131-1-2---1-----1--22121-321-22---------------22-1---------------------------------135112--------------------11---------------------1-------11312---------------11121-111---1131-131-11--2--1-----1---1---1------1----321211--1-111--13114476--------1-----------------------------1--1-1---111 ----BE6-2-2332511111-1--1--11------11111-1----12-111111121-2-1212---11-12221--11211241--1---1-111-14-1-2231D-3t**nvtyaScYdoc*yX*a**rB*m*ZecZkZdioRcffU*cc*Z*ijYKdRGSLVJUMQVObLH----8-1--123463211-1---- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1- * a.24.9 alpha-catenin/vinculin-like
[ 339] --1-1--11111121--1-----21--1-2111-4121422215623337DDB1--1-111121---- 7GC3I325775243EHJ87-8F22II77776BKHGHCDOH443O34421432434323--46C1727BDB13555111--315--1-1225214111112626683434-------11111112211123112321442211132512411-1112--11---1122391------1-1--165432--1113333332533344226323322245-22221111111293-1111111111111111113-21-22-22-2221122211-1-222222----12211111111111-------------1--111---1-22153334354331-1221111-1111--2--4411111121112-1--416654411112A6REC4376467533333332324-22922A2AB981CBB7BDBEH9CC9734469G757787B555555558752662311111111111223112222222122111113A516DA6CHHKHHL98889EEHHAAA95CIHTBGIE23FF94438684F7F917332226444344441147441A332334156116-63342374234525624--2---1-2---4-------11134645374336462234344243454242312261-3133211111158233353444354533-4333444343456333336CDC5532331232232223222326334333221544444444444111311112545522225444626122122231557453443271666675A55677A6755311211111111151111114332774363333331111124111111------------1-----1----------1------11111332331641 --11111-1112-3284676685574822123222-24344442222313479B332532-1-222112212111121121222326114334324-1121142441142857445A4455554645D4Lk81DA86474765C647555742A446461333511132143232---1-21112111484-1443122 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.152.1 AhpD-like
[ 340] -------------------------------------------1------------------------ -------------------------------------------------------------1------------------------------------------11----------------------------------------1-111--------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------11--------------------------------------------------------------------------------------------1------------------------------------------------111111111----------------------------------------------------------------------------------------- ------2------------------------------------------------------------------------------------------------1---1K-*******cbgbfif**e*d**x-*l*YgZZ*ajxcVgdbUjcS*cyfjuLVd***UNmSM****--3--1---2--------------D ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.96.1 Nicotinic receptor ligand binding domain-like
[ 341] ------------------------1------------------------------------------- ----2211222-2--------2---1------211111121--1--3115543332-3--1-27111221--------4--1---------1---------------2-22222222222222212221111111111-----2--------------------------------------12-----1336222222434422225H786962425441824KKMOLJ321999898899999997333392-2CM2-424EC--IQ1431243445947555578B87878A7887555555555555524411-444A13-4E3333333625-S--1232-1-22312--------1--199712353-3111212222121112122131111111111112-11111222111-211122122211111211112222111111111111---1112---------------------1--------1111111111112131111111112111112211111111222132112111121211---41111111111-112-343-121-11111-12111121132222211-------------------------11868111111161111111111111111111--1111211-111B744454CBBBDA99BA-BD9BCB8BBCBBACDBDDCDAE66232BA8A9A9BB9AABAAA6B9688694-666666666565--21----------112144564622222233422222-2---3133333433333332343111111111-9AA8999998A9AB2222222222-------922111133333333221----1-1-44311444145322--------1----161- ----------1--31-113---11-1111--------1111-1-------111--1--1111---1-----------------------1--11------1------15-CJNERFFCEUEHMS**MZQ**h1gZbHSEAKBGeB6CJJ9L98aAABCA37PA9744G54G5B432---21-2----11--1-1-1-1- ----------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------- * d.112.1 Phoshotransferase/anion transport protein
[ 342] --------------1--------22222222311122222222221223332213333333-2272-- 1111111122211111111-11111111111111111111111111121111111111112111112111111112111111111111111111111--1111111111---------------11111112111222113331112211111111111111111111211111111111111111111112111111211111122111111111311111111111112111111111111111-11111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111211111111111121111111111111111111411-111111111112111111112111111111111-11111111122132222222222211111111111121111111111111112-11121111111111111111111111111111111111111111111111111111111111111212111321111111111111111111111111111111111111211111211111112411112111121111111111111111111111111112111111112111211111211222111111111-1111111111111111111111111111-11111111111111111111111112111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1111111111111111111----1-11111--111111-21---1111111111-111 77337674OWA88A748457556746644444445444444446566456658535654565433333433424344354333343444578855654544649AB36VUbSXXRQEFIMMLJaNUGqL**T1bQuHKIEULKQMAHHPHQFBaJVFKTFGkDc*CGHAEeEHVF89B8*77746XHZc6O*79EDDCI ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.79.2 Tubulin C-terminal domain-like
[ 343] ----------------------------------2-------------1------------------- ----21111111-121111-13111111111111111111111111--11111111111111112111-11--------11--11111------------1-----------------------------------22-2111--2---11-11111121111-2-111-11-1---1-11----1111----111111111111111-1----111-------1-----11----------------------------------------------------------------------------------------------------1--1---------1----1---1--------11------1-13111111111111111111111111111111111-1111111121111111111111111111-11121221111111111111111111---11111---------------------112111111111111111111111111111111112111--211111111111111112111111111111211111-1-1-1-1111111-111211111----111211111111111111111111111111111--11--1-1-----------------1----1111---------------------------------------------------------------------------------------------11111----11211---------------11111111111111111111111111111---------1-----------------1-12-------111---1111-----------------------------------1--------1-111- ------1-2---------------1-------------------1-----------1---1----1111-11---111111------------2-1--------1-----r**t***mkqnmpp**u*o**z-*s*inok*osxuYrjod*mW*uYPruShVHCBJ8MAHR88671---------1---------1--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.1.15 Integrin domains
[ 344] --------1122111-----1----------------------1--21-------------1---1-1 -1--21------1-2-------11-3----------1-23-331----2---211--2--41--113--2-1---211--------1---1--1--------1-1-1--------------11---------1--22232---315321----1--------3--1364--1------------1------------------------------1--1-----------1---1-------111-----------------2-1--------------------1---------------------------11---321-1---------------1--------2---21---1---1-------------21-------111-1-1-1----1-----------------11---------11-13----------111--1-------------1-1----------1-------------11------1---------1-----111-1222-211--1-4--1---------------1---1------1---------11-----1---------1-------2---1-121---1---1-----------------------1---1---------1-1---1---1--1--1---1-------------1111111111-1111-111-111-11111------11111-1---111111111----111-------------------11111---1--3----------------1-------1--21-1---11-------1--------------------------1--1-111---1----------1--------------------1---------------------------1-- 53-137B-943161GADWJCJFKLKJEGHJDEGGIB9AB86BDIFHBDA8NQFRDOJIDADE9112131111352-112-243437511GFFDTKbMGHWAW6192-6D5*NTiLUNJMONPYJ*pE*I**mAtZ*CIJIiJPrQ9RGLLlGFmFJAA*POX2GBK9RAA8BD*212E-131321549EG43CC49AE5 -----------------------------------1--------------------------------------------------------------------------------------------------------------------------------------8B122 * b.121.2 Group II dsDNA viruses VP
[ 345] 11-1212--------1-12121121-----2-11-------------2111111111111--131--- -1--3-1-------23122-22--34222222221313541132-411111-112-21--2-1-3355641----------2--2-----1--11----121--21-----------------21---2----1-12312---31211-111----111111--112141-11----1----112-------1232331221322122-111--322------1---1--42-11-11111111111-----311-11--2------11-------------111--------------111131211121221----------221---------------111--11-1121-22-111-13------11-141111-----112111212111122212222222-22133112111-22212232223812112111121111111111111----1-12----------11-----------------2-221-31111211311-------1-1----1116---1----4112--2--------1---2-1-1-----1-1--1111--1--1-----111---1-111-144-1----1-----------1---------123--2---1--11211-2411123234231-----1-----------1-51341112121-2--11211-131111111----3222-1612121121223221111-111-1-3111111-1111--2------2222--1-1---1-----1-----1-----------542432-2-14211741----------2-1112-12411----2--------------1--2211--------1--------------1-----11------1--------2--- 2-22IMs-C5544567565455556742354353434444554543546885A756L86A87312111122121111111211122112AJ45CCD3344224313-J*Y*decZtiQQOOQXS*nKmP**c2iU*STNQbPUiQJWQPPdRMoRkQVrORUKaMA5J7BK6CJV-788O1--71JJKX8QS538GEBA ---2-1--------1----1---------------322-1----------------------------------------------------------------------------------------------------------------------------------31--- * d.166.1 ADP-ribosylation
[ 346] 332-3412111111122-222223111-1-1144411-443319D45752CCA135-2445-3-3116 3--29122333432CFC99-9D33HM999999FIJIA8CG1C7B31-1-352112322--78B2F6J4AB3111112221483221--CB871A55---4623454512---------------65378435435233122236256553331111-1-1--31437676---1----11-144333445239DDDDDF9E8BBDCCB466668CCC312A465677655H85444344644444444445543225424525553345323221668333333324522223212222333333333333322233311122D8FP89788A81817D6522339134624245BC334438223222233223844311111658AA2116344633343333333-43633933445-4777443545437A44324523322345455555515643342-------------------------1111-44551255366339538577799BA77772876A3997133363525475666-63526456244333331-14453JDF65A93A6666335357557824521B6511221112311112222-2222-3132333444423333222234522222255235--151-4------44433434445455444-4554444444444444444444442133323322333333332233434443-211111111111--12--------1536365554452222232246676627335927777555366454534622222222232333333336644433333332221111114222------------2-111111-111-1-----111--1---33122444342363 12---2--3245---214184323332113211321--1--11121233312661-131111211-111-31-1-421122111--21113-142322211-3-12-26362121211212122121218H1-426-2112121222131211122321-1-141251124123--11211---142-71523565453 ----------------------------------------------------------------------------------------------------1---------------------------------------------1--------------1------------- * d.90.1 FMN-dependent nitroreductase-like
[ 347] ----1---23-312B--1111113412131313--1--2-411-1-1--1-13---1211-2------ 29C14482226B1827834139114933333114732895123E224523*255B3331122221343B2111119211136211211432214211--2311312534222222222222223111121122131112311141ZA2212c112111111122137B2R121111131111232111111411212263B48AD44B332242B7525351B1844334126334722223441231625461418C16231584473452323ABB33325471223223335124532222233433532214BA2111125364444744343k4432215562121112164L4321222113412311255511111114632KZ23511454544543448-648597362921877531J3446895323A224732423AAAAAAAA4G85181211111111121421111112U1111116123472311A447682DBH222231393423452D8123A1333331M32C831233174213111377A51T7A3241483443H26345223545247BC231422153333311111241222333211111321b97B2122281XCHC7C852564y34742--131141111112288A354894533673-413576323975689388197832CG32C11431121333215987AM36P4-AEED8FED7584-16212112524521112CEB12224322321131222228DA12345241141712636582222222221444I34324Y34673161621675312111411112111111111111211111-11212111111C1111111361D1141111111 -----------1--1-1---11-----------1--1---------1----------------2--------------------1-------1113-----1--6k-----1----1----------3-79111-2-----------------1---1---3-4111-21E--1------------114-2--11-4-- ----------------------------11-----------------------------------------------1-------------------------------1--1---------1-----------1---------------------------------------- * a.4.12 TrpR-like
[ 348] ------4-22222224--314111-1152-23---11------1--1-13EGG111112-121---*1 GHd1C31222222111111-1A--37111112499953B6233325422222554122--82528-AD991---------1---32119792-4241--19384C6F44--------------21-1111--12235512---62B1224412111111---111964421--11----11-132-1-1--1433333342324254431112342615433-1111111-41111111111111111112112221111223111111111221-------1--1-111111111111-------------111---111112234111112232211221121411--22111431-2--11-112----C2H3331----1368961-22111122122222113-A686998D63--322211331-43-521492B45446683333333345534321-----------------------------1279521312478877A42222775E4566237768B8811556A61455661B7--363252--------233444362---11-11----23-2125--3344CO-41---------1---------111125522134362422111--111111114211551--71-212111132131411112132221-12121222-11212212232444711111122221211222216331--131-2222222122221112---------44624---1-1-111-1---333433-11-5434436856569948657---------1221112112331242338485333---1----551111-1------2-1--1--------1-------------241---111-4721 2111226-C4-1124B7868756898C86355854554755575773367C8CD7A5788783236742367243421325432333853737937586448193726UMY6LJC9F987ABEBMF9E7a*F5LBRB5DDJC9DA9AGA7K85OBJLFIAGE6EBC5J5655BAB56B5R573547A8676A68DCFD3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.69.2 YVTN repeat-like/Quinoprotein amine dehydrogenase
[ 349] 1--1------------------1----11-----111----------31133----1----------- ---1111322121114422-24333322222353324433-23211111312211121--11522123121-111---------1--1213--2------11--111-11111111-1-1111122132211112-----11-1-1352224213321121133235655-1-1--11-11-------1-11312122111121111221223423112222111111111122232322222222211122322111112122211122121113123332222222222222222222222222222222232222222211112222222221122112111111-21111-11121-21112112-111112221-----112111-12111-11111111112---2-1----3--122-1-11-1-1-111--1-323323---------1------222-------1----11-------------1111--211-11-----3----333---1---123-1--12--11212125--2-111121222-------1-61-322111121-1-----412111-143213-23131--11-1111-----------1-1--1111312111111121--2-11111131-------2--1----23-21313332322232-3333222424323543552444713A12222232222222224-3222223--2---------------11111-1---211--------1-11----32113123211-121112111444411111111111111-22-54443111124445455452------1-11------------6--2141------------1--1------1-1----1--221 121-412-1-1324-3124--2144251123111231----1--1-41336253421421-1-12111-11-1--11---1--1-31---111511112--132-11-J6*tptcgYVUOLT*P**TxV**v1yh*NRSVtRUtiBUQWKkOJhMiNNO97D5GMObMBIMNU761352R444458AEH2ADA44365B --------------1----------1-------------------------------------------------------------------------------------------------1----------------------------------------------1-1-- * b.60.1 Lipocalins
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p7-99G64558545525866653A5435524358432522413531122S1121285EA5581345478 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.54.1 Enolase N-terminal domain-like
[ 351] -----------------------------1------------------------1111111------- ---------------------------------------1-------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-2-----1112-12221213-133232331111133-13---2112313-2--1-1--51--1121---1-212111-3----3311-1---141-43512--*iSgQ*WWSYWNUK**Y*f**w6*y*eVZVHXbxhINUIImcS*ET***J7fLitFQ9Ths55*6-1--------2232-24--3331- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.52.4 TBP-interacting protein-like
[ 352] 111111111111112-2-------6456-17212111-1635311111-14---1111211111---- 33K13-3233224354222-262253333333J699A7MK26AI322342118282522154F2559244323338674525121-11OJeO2R833--3726544931222222222222223222325342532335424593A67211121---1----4--154A1-1---1------262432234325656678536B8457345523246734B4245222546248D27336328884245B52B7553544446557744373232569356423123242234623435535542654344413211152343A4492312543753846533324332422DA473FA9617-224222313398223222232364H8322313433323232335-653667437K22412922GF236847423D24352335377777777C22425232222222222242232222222222222214A3522322B98B694B5655ECEK6643347I736NK22EE5864635AF4433394342411122222453K36339411154E3431411364345A32512545-52----------11----13-2-3A84837B312535488A735475691D67736--26323------35683445784554763-7758449444735345433683C4GI77543344385577538954333332-734324444622--131211243473243223224233221232253448334223336A3353747478389711111111143359544746525672336352232121--32442222--------323---------1--------2---22211111121112752 1---2-1-----------1-----------------------1-------11-1--1--------1---1----1------33312----2--1-3-----1-136--4-211--5-----1---------------1----------2-----1--------121-------C--2L---1---1--41--1-33-31 -1-------1-----1-------------1-1----------111-----1--------------------------1-------111---1--------111--1111-11--------------1---1-1----1-111-----1------111-----1------------ * a.60.9 lambda integrase-like, N-terminal domain
[ 353] -------------------------------------------------------------------- --------------------------------------1---------------------------11-------------------------------1--1--1---11111111111111--------------------------------------------------------------------------------11--------------------------------------------------------------------------------------------------------------------------------------11------2-1--1------1-----------------------------1--1--1------------------4------1------------1-------------------------------------------------------------------------------------------2--2-----------------1-----------------------1-----1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------1---------- ---1GD7----1HGP34444665647755454543465454455556655568B4475565643554435334542323333453523343344345365454KFJ-G5*T**s*rweZZ*dZd*wQ*V***3*n*WUTWqWcwWRcYXKrWTwZuTdbNNbJOIKBNGHOIZEI--1-------1-11621-3GNKNA -------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------- * a.91.1 Regulator of G-protein signaling, RGS
[ 354] -------------------------------------------------------------------- -------------------------------------1--------------------------------------------------11-------------------------------------------------------------------------------1--------------------------------------------------------------------------------1-1-------------------------1-------1----2-1--1-1--------------11---2-1-----------------3----------1--2---------------1--------------------1-----------------------1---------------------------1-1-----------------2-----------------------------------------------------11-1-----1-3---------------2-------------------------------------------------------1-------------------------------------------1---------------------------------21-133212123--61---411-242311-1---21----32-1-2111---1---1-111--113-1-------------2---------------------------------------------2-----1-----1----------1-1--------1----------------------------------------------------------------------------- --11--1-----212--21213332132-3222-1-----212-1-4311132333-24244--1-----2-2---1-1-1---1---1-85-2431--2--123---*1*WNUNYYXRPTVVM*kM*R**lA*e*YQOQTVgaPIZOJHUKK*MNQKN96EANIAGRIeC7I841JVK*CCAUa****1**4P3344D -------------------------------------1---------------------------------------------------------1-----------------------------------------------211------------------1---------- * d.10.1 DNA-binding domain
[ 355] 11332332222222231223122234434424123113322224446422323632333341222123 2244333333433344444-455534444443544445564443333533343234334433344544543344433333433332443333233341243333333433333333243333324343343324433333443334444445434444444444334444444444444444334333333333333333333333333355353333334233333333433333333343333323334343433334343443333434233333333222233344444444444333333333333333343333343443444444445442344444434334433344433333343333333343344445444444444444434344444444443414444444444445334444444444434444444444444444444444444444222444443344334433333333344443443434444433343343444333433333333432434433333333323334343333344444443333344343333453444444333433343433343433332231212224443444442232344444433434444444444444444444444414343444344445444444444444444-44344444444444444444444444444444444444444444444444443455555555454334443433333334433444444444344444444444444434444433334333333334444444444444444444444443334344443333343433334334444544445333334-244344344444433422254433343433333 2-22223172311111112111121232211111112111111111111122121111111111111111111111111111112111122111112222212434125173333223332231661344L2-2532122333243434332443542411124253235524364244Q4562484CC1564423242 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.52.3 Prokaryotic type KH domain (KH-domain type II)
[ 356] 111343131111111111222119KFHGJKBB333432222216346857CBA24443433--12--- 122154422222-133333-34116233333542223454343454432223334482--554341647932111122123364-622KKIK3I662--52-A4232G2--------------111---32--26AAAEC333527C88A963244444455675875614434444444444654411-235556565664666666364425666413554411111123322222122222222222223322232322255443223143-2225553222455444444444443333232232233522444222316413775777737434334876375456441444282446162112255149211224444-16--2-------444422244-5-1-41-3--6-9--4423424446544456A78686676622222222-----454--------1--------------------22422245522-1111-211111143122212113675611111212333111112533-1113333333321-57267JB96H747C335526363A39234466777223421111132222222224455711DC4781775676766757677765767687--45636------97557A48888888888-88488888888888888889997744699999999999999999888888832877787777888--3822--222-227673666456233336446--2---11213455555433C5655B3334322244233888755555898772224244222222244B322112211111111541----1-1111111111111121---32222231221974 ------4----------------------------------------------------------------------------------------------------114----1--1----1155---------3----4111------1------11132-1------2-42-2C54P465518466-364553-26 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.286.1 TrkA C-terminal domain-like
[ 357] -------------------------------------------------------------------- --------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1----------------------1---------------------------------------------------------1---1---------------------1--------------1----1--1111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3322--5-51----1---------------------1----------------------------------------------------1-----------------2Q-*o*m*r*iYfTerY**V*n***1*n*ZZZSzVa*vNecaUxQS*W*jokYSUDsW41222K37NU-222S535-2---1----611115 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.14.1 Kringle-like
[ 358] ------------------------2--1-3------------11------------------------ 1-1-*------------11-1---1-111111-----1---7-1--1-3---111--6--44--U-2CHF1-----11--1-------1-2---------4---D-1---------------------1---------11--1411111--1----1----1---11212---1-----1--1------------------------1--11---1----3----------4-----------------------------1---------------------------------------------------------------7-222---222-3-----1-1-2-------12---------------1111---2-----1-1-------1-1111111111--1-212---1----11-1--------1-------------------------------------------------------------1-1-----1----124444--11444432--1--------------11--11--1---131----------1---------------1-------1--11-23A-----4-2222-2-2--------------22---A------1323---2222----2-1---1-----------------------21--------1--1-11---------111--1311111111111111---1-------------------------------1-B--111---3----4--------------6-----------11-3-2--------------1111-1--11----------------1---------------1--------1-----------------------------1-- 5557H7T-9221559414454256574-13-112311433524111547B6764344644441252122113333-5221311-22142ET91fJY85AM32-TSf79E6*steddYQOQURWRuhSvQ**o6rewRSLLmOWhRKVPQJgMMxPcXVYROaYlPvDWILSGMMB25H2Q121-17BEQ2DH94DLObH --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.42.2 Ricin B-like lectins
[ 359] --11--1111111111-111111122222121111112111111-11111231111122-1111--11 1211122222222221123-2122122222212222232221212322122132111111421122111122111111112111111122221111---13222311121-1111----111111111111132122222111111122222111112211211213211111223211212111111122111111111111111112111111111112111111111311111211111111111111111-11111-1-11111111111111121111111111111111111111111122111-1111111111111111111111111112111111111112111222112111111121111221233321112123442222333222222222222-223224232322322233223211222222222222222222222221222221311222222111111112121121121111211111222222222222333322223333222331223112222213221121222222222111111112122222111111121111123222321212222222111111111111-1-------11111111311211111212222111111111111221-12221-1-11122222221111121111-11111111111111111111112212211111111111111112112222121222222222222-11122222222222121222111-1111111111121112222133432222322222222222222222111122222211112321121111122221211221111--------1--------1------------------1-111111112122 5512FQC-H66387776767977666666666676668787AA6677596678A776699888655652L6554458466555677766697677F88867F7DDG1CPBMOVPZZQGJFGHKIdSFYE**N3RMdBDIDQFIVGDIHHHIDEQGNGIJAKJBB9EAM69FCE995898L76767DOTS7QG46LNKI6 ---1---------------1---------------112-1--------------------------------------------------------------------------------------------------------------------------------------- * d.143.1 SAICAR synthase-like
[ 360] 11-----1----------------1--111--------1-11------11------------------ ----3------------------------------------1----------------------1---12----------1----1--2313-211------11431-1------------------111211-1---12----------------------11--1111-------------11----1----------------------------------111111------------------------1-----------------------------------------------------------------------------------------------1----------------1----1-4-111------------1---------------1----------1--111-------11---22---------------------11-1---------------11-1111-11-------2---31113A335373333355416665436242326--222112--32312-111---111----------2-1--1-1----------211-2332-111132---------------------------1133----1--12----21-1-112-12-2-1----11-------H9--36FCIICCDFAFB-GBBJB5AFDGIAEAABAA8FBA237FHE6CECEEFFFDEEEEDB4745689--DEEECECCEDDD--21-1--1----12---------1---11---44334-4-11-178672425-2352-343------------1------4121144222222221111------------------------------------------------------1----1 431124E-cLABFGU-11111111111111111111211112111111211111211111112-1111-12--1112-211111--1221-3144321122216A616HFrRPKLISIGKEHLOXPEgI**Z1wUmHJKGUEIVKCMMHHSDDfMObJRDGJHOM47B339v*NN3LMI*11131GJNO1HF34JUFHF ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.1.11 PapD-like
[ 361] 22----3111111113-1------1-121142--1112-----231121-311122332231221-11 7682831543322234411-14--45111115433357F9445364335554354255224443536794221112211-135432322121-21111127155A53461111111111111122223312222233344---5343353323322233334423246713334223324423533323321422222222122222232775422244236453323333233333333333333324433311-33-22221122332-11-1333222211111111111111111222212211112211211222221112------------1---111122-221-114213214213111-21-44395582222246B685476457522222222225-89489586485-87759899AA77465132832423233333333335354335311-------1111111111111111--1-13142234434EBDCBE6555588BC555525A69659645554754556465A366633424422222223345588231-12142622231212-2-2-46436225---1211111----11-11-343212244-351545732333344446543334436--224-51-1---44551444444444444-44444444444444444443435533445444444444444442444444411322222222222111211111222337588---212-11-1----666663546363555557C76777666551----1---42332324325644466565655553333223-331122111111113-211111-1-11-241-1-1-211---13111121112635 5445557-LA71333564433344245453333333443434445423445545351453322321---1---211---1121223323464647241333225451537ABF8CC55552585DA4B4Ge7-98C3665F58F835564953B6A56B35664348968833964565n56474IDGH5C78395974 ------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ * d.227.1 OsmC-like
[ 362] ------------------------1----1--6---------------3---------1-------1- -----141-------11----1----------1---13-------------------2----2-4----2--------2311-------11---------1---2-1----------------------------533-21114-4--1-------1-2---2---2311------------21512-----1WJhVgcJlAshjePg8C665-lsA---1--5BB9CB8472EEGCGE8CEEEEEE24241G162332--2-6622--1-3--36522224425722-----------------24322-271----1-1------1111111111-2--222362122---1--1-1--1--------1---7---1------------1-------------------------4------1-------2---2--111-11-----------------------1----------------------------1-D7547I2222561112223-777744227244A--555-----9---1--11----31--------------5-------------3-8--241--11--3-----------------------------43---1----------211-421-1--2-1-------------aJ--4MXUfdhUbeVTS-bSNbUNJcaXcRdUWUWWJQNO35GNpaDRRRUUSXXYQRRRVVCGCMFOL--DDDDEDBCCEEE--------------2-----1---3---3----44424-3-12--7967-43B-2353-545------------2------42---52-----11-5232--------11--------1----------------------------1------------ -2-11-----2----21-11-1-----122322--12----------1-1-11211-11---B-1123-52-3133311225775D-----11--21----1-3-1-211523-134121-11154-3-8N41225-2--211251-2-2212311111---2413121--2211---1--1---2222-21-14--2- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.2.3 Bacterial adhesins
[ 363] 22121222222222222222222222222222222222222222222622442222222222222122 3333222222222222122-2222222222222222222232222222322222222222222232222222222222222223362344442422222222222223244444444444444543222224224222222222344224422222222222422222222222222222222222244233333333333333333333333333333333335555553322222222222222222222422222222222222222222222222222222422422444242424443444444444422222222233333555555555535335444755543553333333353333333544335344322222524343333333322222222222-3333333343323222334222222233343252553332222222222252453222222222222222222222222222222223333444354446547575445588883734843332233433333342543335433363222222235523333523553335444433333357766463252322222222222222222222233222352333335353534355433343344443222432333133343344343443333233-443343333343523322322244444555555555555555532334334635666665665652242222223555428352222222222222222222222222534434333353333345422222222233336333337553333444444452222223522333333333333346----2-242323222253225333332333533534322 4434334-E65234444264444444444443444424443434443344444344424444434444234444444354434433444454434744444429CA246396967A5534466595485Ba616665435916675523454363B44645C56454B45D58346454j3333398CD4A64453344 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.49.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
[ 364] -------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1----------1-1---11-1111111----1-11-1111-1--111---1----------------------------------2-222----2-111--232****y**UDENX*R**F*j***3wu*AQIH*YdvYEgIGC*D9*R*v**mwlBbA5E8KKAPbM91----------5141----16241 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.22.1 Serine protease inhibitors
[ 365] --------------------------------------------------1----------------- ------------1----11-12----11111---------13-----1---222211---G71--1----------------------111---------22---71--------------------------2-83323---1-2----------5---------------12------------1------1111111--1--11--------11-------------61----------------------------------------------111-----------------------------------------5--1------1-----4--1---2-111----1-32--1-------4---3------------------1---------------------1------------------------------------------------------------------------------------------------1-------1-------2---------------1--1--1-1---1--------------1HA-------11----5-11135--2-216B--------------1-----------3-------4----1-3111---2332-7--3------4--------------1-----------------------------------34-----------------1-------------------------1-1-21121--1-------------------------1--5------4----------111111111--22-------------------------------1111--------1--------------------------------------4-- ED99SWD-WB9-88856875446554444455554534443444346757856955A668676567874688756662756766573457G7678687766696991C**rUVRUSPOLQKLMSvhLaL**X7bL*PKNLYIPXMKPNTLSKKiLSOLNJQEFOOEILHNbFFYO5LPL*ECCHDaQPh6ZiCRLjOSV ---------------------1---------------------------------------------------------------------1------------------------------------------------------------------------------2---- * b.69.5 RCC1/BLIP-II
[ 366] 11------33333331-2------3113-91-------------------1-1--1-2---------- BFH-R--1---1-------------2----------23332--C7D6-6AA-3421-2-----5935EF33A5554331-12------UT*g-M77---BP-A1X44-G------------------------1-33376---5-1--1-------------------2-------------32---A9-4---------1-------23111---1412--11-222233W---------------1--133123312111111114312122221211122221--111111211111111111211111-3322233316---6----------A----5639-21--38--11----6---13-7---3-39331-1----1-------11------------3-11-111132---855788397833--412--------1---------111----2-------------------------------6-2-----154444613333443-4444336431644--------------22----1-1-----------1---1---------1------1-11--------3-----------------------------52531A2-B-22-1-1--2----2-22-21------1------34332336776666666-5646666666576666663545222--241223222212122153234446--233333323333-----------------3222224------11-----------1311111111-11111213111-121-1-1557-222224-6644AABAA7864444---21111----------1-----------------------------23-777681I71 ----65H---2---2FDIAKHJBLFJN3333335644222-2231188GNMNaLGBJEGBBD245-3--1--417---3--22121--16E7D6A52423492421-4P4*AFAJFFA896AGAJM9LAu*N-RKR4978ICCJA3DA44F84KCGCCC779irl94933BEJY9-222N22248ABBED9733PKQS8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.1.4 beta-Galactosidase/glucuronidase domain
[ 367] --112112111111132311----11111113-312411-21-13-2--2234311222-1---1-11 35718124333232-2211-13222-11111121116-112433-1-12112421-----2221A-28953----2211312112122331623333115737672813-------1--211211212-2321436563211-426241-12-------1111--11263-2----12-1--3432211-4224545545616453442244346551111113------32--------1-11----211-1-1-11-----1111212-111-1--211-111422-----------2222222222212244111224-2328344444562523-4434453112313321233131425422321-4442522532331124643352335333133332223-24432345252-543254356522441114315355213111111111221341312-11111------22121-1---1--11133332333125445444333322233333223645435--675622--143341244121222111111111537465544242337331176734765445656532131112222121111111113123242221245242121344311112224321114--152-3--11112322412-----------------------------144322-13322233223121312311222--11-322222222222----1112112123454311111-12112111144444341221254453464336333333523223222211212222233123232534433423231124222222---2-222--252E32-111112-11112-11-111122211-11122-2 1221559-L73835A89KAC9D9BA467AB77CA7957372553548CABAB8C67DLBACB12326346437544D-14354433343CM59A9J6A8969365917IGPCDEIDI76548A4TO6D8j*L3LHRAA9AH49I849886F56BBB88C35C87C36C58A6BC74K969--68CD79AC9G626B7CD --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * a.111.1 Acid phosphatase/Vanadium-dependent haloperoxidase
[ 368] -----------------------------1-------------------------------------- ---------------------------------------------------------------------------1----------------------------1-----------1-------------------------------------------------111----------------11------------------------------------1---------------------------------------------------111------------------------------------------------------------------------------------------------1-------------------------------------------------------------1---1-------------------------------------1------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------1-----------------------------------------------------1----1-------------------------------------------------1-1-----------------------11--------------------------------------------1--------------------------------------------------------------------------11-- ----------1----1-11-1------------11-------------1--1--22---11-2--------1--1------------------1--------1-----2--a*lI*TaTbbinQ**X*Z**l-***SSUadWD*zEQtUs*WJjTOMKe---1-111----1--11-2-1---12-112-11---12-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.19.1 MHC antigen-recognition domain
[ 369] -----------------1-----11--------1-----1-------------1-111---------- 1-1----------1-----------1----------12-------1---------1-----------1------------------------------------1---------------------------1------------------1----1-------------------------1-------1-2------1------------------------------1--------------------------------------------------------------------11--111111111--------------1-------------------------2----111-----------11-----------1-----------------------------1---------------1-----------4-----22222222----1------------------------1-----1----1------6--1---1------------1--2---1-------------------1----11--------------1-----4---------------------2---------------------------------1--1-1-------3-----1----11----1-----------------------------------------------------------------1----------------------1-1---------2-2-3-1------------------------1--------1------2-----------1--1-------------1--1-1-2------------------------------------------------------------------- 465576M-cHD576847758797677877787767587675778778666667777866666965555-555655553655745658786B579695554676C9C2KbEsmmhjjoUSPSWVRuiSvQ**fIrZ*UPURfNVcUUUSSSfRUtQhYUTKbjHdPPFPGGYCDZK4DBA*86588E8FH5BF98abUWJ --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.148.1 Hect, E3 ligase catalytic domain
[ 370] 113-111122222121213222224112121221211111112331312288711211222---1--3 2231221344312122211-121142111112635357341424434412227251211133532134531233322213143222222221-122---2314324332--------------1231231132311112221222A52411111112123211112134---------1---132112215363333334323333332322243333544243444444463333333333333333332221212311111331144-1-131333222111131122222222222222222222322222322222231224533334332321311223212211311311123111211111111232142261111125456316325231222-222226-554454635432433246333233453137-33133-21333333334333385211111111--1111111111111111111-54482-11-232222231111334322221313C2334124B234143432333223332221--11112-3123322331221131222-4333225334443344232331222221-1-------21222554324B2375332222234232282223842--24122------22112222221222222-222212222222222222243322--22222222222222222322222222-333332333333---32222233332632211121311--121235455643-223133351433233466112122222222522252223233333543444433311111141222222111111111-1-----------------1-------22222212221111 1222573-844255677A978876797667778665787888977798778AA9689779996554443546564776764655465346D4766B6775556A7916M9KAH9CFF999BB9AHF9G9ZxE-HEM79ABH8AB989BB9B99HAFGCE9D8EAC67J689CKC54532G23336D9CJ9F956EA8C3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.59.1 Cation efflux protein transmembrane domain-like
[ 371] 32-1-2544565556411333214311131221-------------1-13421----2--12113-11 124462-1221-2-45577-73337677878553334BD7166432221111143311--645266B4531--------11141121112-1-1--1--2212122413-1--111-------24432343323366666---33363255333332223232324444312312222112222233--1312444433342454335532222444544131-------21-----------------------11211---11--11---11--1---------------------------------------1------4-122222222222-123211131-1-1-12-472221-142--1211-334311311111449793366675545455553457-67765D6A5951755656A658868533176644565653333333343342338------------1-1111111-11---1-21A61289899BBBEADA99AAAAHEABBBA9EBHADAA35668A9766D7B78B6575443563334445554A7715854446565667-34414323277675A232--112211212222232221221255321442613234222212332222225353---6555------43223336445757666-4666666666466666663454322333333333334334333433444441-333433333333---1112231222426663333211223233312222233453638888686556668555532212321222223333332223355433333343333125-223433--------1-1-------------1-1----------11---2---422- 1-11342-852-2334574775588956634334343666466334554478DD6445344525444434225253313434446412157453326452342433-35AA4757553424534B52529K5-337143234341232434313345389B957532726347J42345a43452CC7U7DA5588662 -----1-------------1----1------------------------------------------------------------------------------------------------------------------------------------------------------ * d.58.32 FAD-linked oxidases, C-terminal domain
[ 372] ---------------------------------------------------1-----1---------- -----------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------1-----------------1-11-111111-1-----------------------------------1-----1---1-----------------------------------------------------------------------------1-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1--------------------------------------1-------------------------------------------------------------------------1----------------------1---------------------------------------1-11---1---------------------------------------------------------------------------- 746AAAE-XD5179A56678888999A66554577666566555554667877678576555A766465585655664666555466668H86B8845665CAHFI-G*DXomfkgcSNJNPRR*oMiR**d8sa*MNTQhQReQMSRLKaOFvRTPPPJCNEVGulpvyeGPIO5JE9pDCBCETUao6hIZJEBCBK ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * c.13.1 CRAL/TRIO domain
[ 373] 11112222112111221311211322233133--1-11-----43-13-1232111111114431--- 254-C12222323166511-14--48111112767623942B274132123-41312311314252649E2----111212131-11111----11---22-1-3121---------------11112112212122223---62131411144--1-12--1---66512222222222122211111-2-7A9B9BC98489BAB9233337A883224443222221461333333333333333111222213312111222222512-126752223111323222222222221111111121111222111---1-2456333222222323331121112121-2111232121413231-1--32522211112173G9B12321-4122222222216-988965982B31D9977789A9BBA43212451111315222222221342-32511--------------------------1--29-39CA56BBBCCB533337888554528B5A99FB-1445356338444I7-42-3538411111111-2142144-113--23221-67314551333238D553112212222212-------121133354-111333233222221133212212113---2323------77743745556587754-5565767555575665664999654446766666666666667B534554521622222222222-----211233331-645---------------877781522561DCEE99B87B8C94987144435434---1323223531348613133---1111--1411--11-111--1--1-----1---1-2------21--1---211222223237-2 11-18A5-C5312267BE78BABBD878955456766555655455A98C569857645523112111111143111111211131111A74B8523442321916-2a6A223221311113676352IcA-44B3222613231212221244232333356442643545342644h342A3556EC9486B5787 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.33.1 Isochorismatase-like hydrolases
[ 374] 11-----11---1-1------11------1-1---1-1-111----2--11----11-11--1----1 --1---1-------------------------1111-2---------------------------1--1-1--------------3----------------2-11-1-21--1-1--132331---------11-------1--11----3------1----1-122-5--------------1-------1222332-5-2-21-12222321321122--1--1--121----1----2----1-1-3-1--1--11211--11---1---------1--1----111---------2221--1121122--------1-21-2---1111-----1111122------1-132-121----1111112-12-----2-11--1-1--1----2-----------------------2-11-----1-------------11---------------1-1-----------12--111--1----11--1-----------------------------------31-1-----1--11--11-1-------1--------------11--1113--1221-------2---1-----2-21--2212412-2-11-111112111-1-111---1-1--1-1-1---11-21122--3-11------------1---------------2--1-1---------1------1-1----1--21--1---1----------------------1-3--1--2122--1----1--1-11-1-11-3221221---------1---1313211-----------2---111-1112-2221-----111--------1-3333-----1---12-2----1--11-----1-----11--11-31-2-12--- 66325DC-L9E8BBD635B24645234117756338922231344456344577134127645543343631612342335231624544823267344-33245A264EuXWXWseMTJMMgO**N*P**t8*h*XPLUiJcoXJYRNOqPL*PfXXkIIIHLG9DLCIRDPJA3423F34532*BAC4HB4CFLII2 -------------------1---------------1---------------------------------------------------------------------------------------1------1-------------------------------------------- * a.114.1 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain
[ 375] ----------------------------------1--------------1132--------------- ------------------1-1---1-111111----1--------------------------------------------------------------------11-1-------------------------------------------------------------------------------------------------------1-----1----------------------------------1-----1-1---66--11-----11-----------------------------------------------1111111111--1----332------------------------------------------1----11121--------------------------------------------------1------------------------------------------------------------------------------------------------------1----------------------------1-----1-12-----------11---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------1-----------------------------------------------------------------------------------------------------------------2--3--1------- 3311IHC-uQB5MJaORPLSPQRZTVTNOILKKNQGINHKGMKGKMLLMQRRZSQRMJMLMMFFE9CC5D87FBE56466BCCDDE697NiPRPOPMHLIIIIhee1BsJNGFBECFCACBBHBLO9MAQ*H1LEN9BBAJBEHF7ECA7KE6MALFGB788CKF9AJEIJBFMF8ECK*LJI7CPHWLNFFKRDGHGS --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.120.1 Cytochrome b5-like heme/steroid binding domain
[ 376] -------------------------------------------------------------------- ------------------------------------------------------------------11----------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1----1---2-----11---------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 8534JFK-aG959CFCMLA6A87A88987997A9666AAA7A9463F9EDAFCEACBAB89C744424225435434243444433355TUDM***2448K74DEC-FhG*UcUXVSLDICHMH*aDpH**b4oU*BIEDTGJSIDMGEGOFBbHXKKNFHIDQMzBYTWUDJL93*HcT776*OGFEMGHJCBGQPR* --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * g.85.1 HIT/MYND zinc finger-like
[ 377] 111-111111111111--------62224-22--------1---2--11-----11111211111--- 3432221111122222222-2422422222224333226623242242122178542222225238A3222-------1--1B411622322122311113222422221111111111111122222222222233333---343433333333333333333333334333333333333332332232222222222222222222222222222222222222222212222222222222222222211111111111111111111---11122212221111111111111111111111111111111111111122112222222121122212222111221111441212222222412113154333333333735433333343445645645561774796747P42FAB9B9CBAEEF99333AE86667JGP444444445333834322222222222222222222222222222A357323355355555564444556A55553557646432233753333533345223352533333333333333321322223222222143322221222223312121111111111111111111111133332323833433434433433343334443212333522222233333333443333333-432333333343333333333333334333333333333333333333333323333333333332223333334333333552222223222222224333335333536666666AA796638883333333333333323333334334533333333333323312222231111111121211111-111211111111111111122222222223322 54--453-A3413334454455345473343344443333333333453357555464345433523424433652423334345433335444352443233465-4B5L88688A6663575875A5N*71A8H46738656636546753A665585AA4878456A549764446U6575582394553752548 ----------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------- * d.250.1 Folate-binding domain
[ 378] -----------------------1464121312-212122222212211-1--1------31--1--- 3251711233332133244-442255444444433344983433423-2441464233--452162985633222222---15111-2442322--211141134252212222221111111111312111121-33112224133333332333212233333246333111222121223221122232577777778576557767225575631222--34443284-22222222222222-22--42--11-1-1-111111-22-----1-1--------------------------------1---------245227765557151-4321222525--212223322222511--13-422-3533222222226342235344466665655666-335336366732C9966BA96869633453473277256333333335333253422-22222----1111111111111222223573447776CCC9B996665AA7A646636D7877772255553155985466224222293244444423224232421222311111132322222233342221312221111111111111111212122642565846667854454644446466468223252222112153334336666666666-66666666446662264275B5434553233333333333333624454443132222222222222262222254443778B222422222222233888786456672DDFD7G8B5B8EB56771----22--23232555456865586BA9AAAA844442224223344---------------1-----1--------------22-33121212321 ----744-621111578736665HDB544443276666666672--2438CBMF66554113311--21-121-141112111121-13283843322214-7--6-2I4K5434522222142421327E3-33333323122-3322222333324922294533511255672334933223631D5864554226 -------1-----------------------------------------------------------------------------------------------------------------------------------------------------1----------------- * d.21.1 Diaminopimelate epimerase-like
[ 379] --1-1------------1-----11--111111111112222322111222221-1-1---111211- 2232532444432233333-3222233333322222532223332222333432322411433243476422222222223323332255564534-113323343423--------------132222222332333331114232433333333334333354344433333444333336542222222333333333433333323333333422233332222226335555555555555534433221222221213322221223432221111111222433333333331111111111111222222222323134444334433374223333322112443244232422232242124335433344444423354333335344444444444-4434454456435667446444444455333544442363333333334442464---11111----1111111111111----2557542444234445535554334266673445424332222422322223322323322254444444446543446732245433666255545444433335423443444444444544444445455544775444645674444464444445435443-11554411111155664545556556555-555555655655555555755555667667766766667677654445555515554655455651135222224444545472222222222222253336324453646676775778886667743433533334445555555757744555555554444224222222211111111211-------------------------33433222223453 12--334-4111111121-13324252111111112232332211141122224-1112212111111121111111-1111111111322121111121121112-376748D74A2546344BI4G4FY516384433835C34446565571856A7982A3312572444D2463Q2223576491555376853 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * b.49.2 Alanine racemase C-terminal domain-like
[ 380] -------------------------------------------------------------------- ----2---------13311-11--3111111211111-31-322-----------------------111------------------1----1-----------------------------------------1111----1-2-121--11----1-----3----1-------1-----------------------------------------------111----------------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------1----------------------------------------------------------------------------------------------------------------1-------------------------------------1------------1---------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------ 1122bhB-E64177DEHIHQQYVbchhFFCDGFG9BDD9D9DEDEDKFHIWTkaNSEE9ABB98E9A6-AA6CDFHG2GHIEBBJN244GJAHACGEEG6CACJJI3PWL9A89AC755555A59E775JnA-955555455568254415527567647EP8FAFFdIH*BB718UKE*BDBOWuwz*H**FB****T ---1---------------1---------------111-1--------------------------------------------------------------------------------------------------------------------------------------- * a.120.1 gene 59 helicase assembly protein
[ 381] 1112214433333253222212-321133274-----1-----111121-11111212-225215-12 36C-944533522253333-7311493333343333499926134353322-565836--543174956531111111223361-1--1111-1112--1312842444-------11111111-11------113445411135133222211131121121211--1311111111111173533113225778789675888988G8445598836A9C45555553G96777676777777779989533132232242553363121334223222222333333333333333222222222222244443334451813456455643552F1155642715153-1-2212111913--23-5-C-3444611111219DA3327668211111111116-33843743372-A55332455573443423764545577111111116664-1--11-1-111---1111111111111111-1245751387356886A75444366465554349458A791257511712B392C713--11-141-11111----142311312311--13-22111124222223514-421122122211111-111--122224123224354422112-16211-4-43-34--3111121-11122F53324442422244-44445234344244444435553513321222222222212224332222421----1-------1--4222221222114322312113222222133331311131216646545727876274411---21-12122611111434333122222122122211-4111111---1--112-11-4-1--11--------11------22222122211413 ----684-E83113566649755A8B833332313343133231113446B7F757556555746476243373553244444464222AG667968787653664-224I7C6676323454595262DU5-585-33374583245235238555586451B533321335663651V---3777AC5632324346 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.19 Bacterial exopeptidase dimerisation domain
[ 382] ----1-31111111111-12222-1-------121--------1-1-1--2--1-------2----11 122-2-------------------1-----------1----121-------------------11--121---------1---1------------------1--------------------1-----------33234---5-21111121--------112-23231----------1----11----------------------1---2---------------------------------1----2-1----1----------11---111----------------------------------------------11-111--11---1---------1---1--------1-------------1------------1----1-------------------------1-----------------1-11211111------------1-11-----1-------------------------------1---11----1--------------1---1511--11-------------1-1------------------14----1---------1--1--1------2-2---------------------------------12-1111111-11111-1111-13---1------------------------------------------------------------------------------------------------------------2----------------------------------------------------------111111111-----1-1----1111--2---------------1----------------------------------------- 322233A-XFC19BC5676598A7657886747675574763678877886475266685464344433544434442245555547462566B594668456ABB15j2hfiZbetQScKRXU*yN*K**k2xk*VQNEiKWVcKVPTOgNRyMOQXT7A5ADISAoHKa9KJ8155Hk396C9Qdz*5gT4CKqUaH ----------111------------------------------------------------------------------------------------------------------------------------------------------------------------------ * g.41.11 Ran binding protein zinc finger-like
[ 383] --111---222222---1-1---21-----1---1---1--112-1-1-212-24544665---1--- 43F-3---11-------33-3---1-33333---------2426131------1------21-335553912--------2-2-2---3431-311---131--413-3----------11-1----------112223321-41233322311----1---12223544-------1---11----1122-23333323333343331-2222333--2----------45---------------------------1-1-------1---------------1-----------------------------111----1--------------3-11----18---2111-2143221-----11-2-1-I111------3363333234333----------1-5343343312--3111235111-1-3212-111111-114444444422223413------------11-1-211-1--1-----1--15111114554556222255322222-35333234--1111-2--1----1--2---22--------222111151---21323----374344365112165-6111-1-----1-1------------4411---11-----211---------1-1--1---2---------12---1-1222122222-2212222212222221221111--2311111-1111111111-2111---1--111111111111---1-----2333522-1----1---------1----------22112122222-2-3-111------------11------1---2111111---1111---122----1-------1--1-----------------1-------1-21111122291 35348761F54445666A7EIH9DHD7668988988597A899666766666B877BA67877555564678655553555666568578A7678C66557D8666278EQRSVQkLDDFCAIDMPHSHs*N1SLcCGCDKFGXJBGEFDLBBaEQLKjCGEGHMF8GIFQ6DBA6546a44544E*q*8*g6638549 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.102.4 Terpenoid cyclases/Protein prenyltransferases
[ 384] 22211133333333333233333332222332323344434342222212222322211112223222 3351521222222231111-1111111111111111222222211112211122222211222122333321111111121232222222221211111221222223211111111111111111111122113333221112311111111111111111111111111111111111112222222211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111123223333333323212222233222232221233223223312222313132222232222222121123233222222222222133333333223-2222222222433312222222322321111111111122322222222221122111111111111122221111223332244444444444444344443445333432333332233332333223232334334333323323312322231231112243333444233434223211111111111111111112211222333434323323333323333333334333211232211122233332434444444444-44444444444444444444443334444444444444444444444444431334334534333221322222222232332344333233322223331333322233333334323434432221221122122333333333333334422222222222222212212221111111121111111-111111111111111111111111111112111 45337661ID8598776466666676666556655555556556666666666665556666566565356554666366466664777686656645446557CG38AGS9FBCD955C65F47F6K6N*6-DFF4B73e46DB47753A43C6B6688HN69789H948EA978567t55657ICZM6C87789687 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * b.44.1 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
[ 385] -------------------------------------------------------------------- --1--------------------------------------2------------1-----1-1------------------211------12----------------------------------2461112------------K57-217--223--316-4--48DQ1--1-2---2------------------11--211-22------2-3----------------1----------11-112--1---21------1--------2---1-1--858----22--12211-1-11-2131---1------------------------1-1----1----1--------------------------3116-----1141-1----131----------1-447665512----11259935324-----3264144537-------------4---------------------------1--2--23-----1-2---2---------1---------211-----61-------322--5---912--41326---1--------211-4--1--2----2-3----11----1-3---------------1--1----121-21--11-11116-21-111-12113---1------------3----321-12----3-----1---3-----------11115----------------2---------311111111111--71-----2112--6-1214---------2----15----147-1111221-11121-1A4---------------111163-----1-------1121--2----------1--1-------------1----------------------------- 21----3-4-------------------------------------1------------------------------------------------1-1-------1-1-1*******TRXVadT**L*Q***3*y*SQTNrQjkWCcOKK*JL*c*WplKY*QE98CF55bMWM3---------11-1----1---1-- ---------------------1-------------------------1-------------------------------------------------------1-------------------1---11111-----1--1-------------111------------------ * b.80.7 beta-Roll
[ 386] --1---3122222223--211213211411112132322222222226211111--1--3-112--12 6964C------2-222222-2222222222222222222253233-231444535533115321A4663622222222-22111211131----------211-1-111---------------1111111111112121223412432114112222111323232222212222222222842--221624666666654756666454463675335-4-222222263111111111111111111111111--121--11-----1-1112221111---22222222222122-------------22222222211113222222222222344----213-15324333322231334342111112---------11111213-11211111111111--11111311--21--------1---112122111111-1-111111111111-221-----------------------------2112222222265555655554443367773864322222222221211112121111-21142-1--1--11132142322122222112-32313232122114325-111-------111111111111--22---2--3112-6333352133113331138-122222----------------------------------------------11-----------------------------1--------------4---------2211----------------22222112212211112212221111111---------3-1-211111221111232322112----212111---1--------------------------------------2-11-111222- ----863---1-46ACIIE8B899A98996867KJHMLKLILL768EDCILJHMGIOE9AAAC33333236532444456344336433AbJIA9C33423A43781753dLGGIIHD9CBEEHOODMD**Q-SJY9HBCJAGGBBFEB9EBAFEHCBECGFER7UEVJMWFNH311319--1344657F9G9234232 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.3 Protease propeptides/inhibitors
[ 387] 65333342333333332222223221111111112231111121311122223522323221112321 3121212222121112211-11111111111121211224112231111311212112221321221331212111221121231322565513341--13111222131111111111111111111111111211121111124344111121111121211132325111112111111111222212434545745454655664433336452453323122222433222222123222222444242111122212232211342233221225223322222222222222222222223222222222222222545444444544542744355435334234214434121222112212321142222121111A364115314311131111122-346457362A21B882667877544221115241221483333333314223314111121121111111111111111111122169316885DEQQNJJA8CC8DDGCCFDD7CRGEDAIC1145755AC5M3B2C63341212821211111121665224111221122241111111111442234211111211311211232221111221545522422124324243332222332244331-111221--11144463484444443444-5644343444434444443689552443222332233342422943444544-355555455844--31111111212113522222323322233322112112111A19AGAEEAC7ACE967891111111111364343444C42558443943222623311311111111111111111112112-111-11211112111111131121212221321 1142123-B34622223332241414533443562242113123323111635253222353521312221121122243223312212121334633213714241151E5657412242243B7252OX214243323323522233252153435744D38246428768622353R44334945924B4573436 --------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------1---- * e.10.1 Prokaryotic type I DNA topoisomerase
[ 388] 22122212222211112111111331123222112232234422111232333322222221112111 3471712121212135444-46114544444456787497232244231212493111113351646585111111111121141211121111111--13233633141111111111111131111112221111123112212111111111122222211112221311344414314312111212131111111111111213233431211213211111111441111211311111111121112111112111111111212111111111111111111111111111111111111111111111111111224211111112212111333331211322122214324343223123121332261111134A457333343322222222224-222233224F2328835666767B34141223343331111111111222121221111111111111111112111111111113442112122223322322223236343321253443211232263534233522123112213333333222542212111212113121323221211546534122122322222211111111121311212214213223224222123222233332221-12221-1111122321222222222222-222222222222222222122233232323222333332312311-1222211223322323222112121222112212432111224122221222222222311121543353454444544441111111112222222222132224336366222222211211111221211111121111111-111111112111111111111111212232714 2313A961MAA354865977769666666679866765555666555888766657766BB93464431544444442445445445556B55A7788875785773ATIH8BAA9B5487695EF7E5d*I1H8K4666856B85A667C42A6BB8A7A8F8BS8764D97674698j765A5E88A8C8658CBA4 ---2--11-----------2---------------331-2---------------------11-111-1-----------1-------------1-------1-----------------------1---------------------------------1---2---1-322-- * d.142.2 DNA ligase/mRNA capping enzyme, catalytic domain
[ 389] --------------------1--------1--------------------121--------------- 1352A22222222232224-232223222222433323523856-2644211---211--653269778H-3---1--22212----111---------15111431-----------------211211111-211131---E112331151-11------7111SURC------------411-----53A222222222222232GT985D2226682Q3211111166111111111111111111111-1-34--11111--26--1---321--------------------------------------------384J865659546A5B2764111A59--4115277442C71429A83111---63464344368GCDA769A9A97778788877A-CBAA9BBDCD61AB9BCBCDDBEEAB744897A878668-------------344------------21--22121-22-----142211232241112212333322-15333141122111----35135543121--13111-32-------32-241424-3-2--11----12214121112127941----------1------------17--342262213-33334334444433444344--3221-------33254333223333323-2332222222232333332242233232322222222222222322342232-233333333333--3211111----32822---11-------1--22223333575444542335222223332---------152333333324123526676B222----1131-------------------------------------------------------2 ----33------11111212121111322222211111-11-122221111211-12--111121-1---2211-2111-1122-2-----111--111--------121cNQHQHQIGFGJEHURBPGS*N-OIbFFEFOFDIFAJKEAJEAQFEBEV6DIJ2582456645K12135654112642G163------- 1---------111-1------1------------------------------------------------------------111---11-12-----------1----------------------------1---------------1-1----------------------- * a.20.1 PGBD-like
[ 390] 11----1-----------------------------------------1-1----------------- 549----------------------------------------------------------------------------------21-JHND-7652--9A365A67821------1------5554447236-7----------2323111111123262233122441122111392121121----7-------------------1--------1------------1------------------------------------------------------1--11------------------------------------------------------1---------------1--------1361155433745635VKQBDDKCFGE889A8BB9BB9-558656BA7F217984555677658C3634463222312444444443332-171FFOQOHHH212223443233332244335-2753243322AAABA956774778877774889B6945124542942239333-3515732728K88DB712222-B5-13-2-222---19995869753333945-1321222221212----1--221291177157CC7743ABACA97A89999BAF8EH--332351-1111676A8B57IH9797A87-L68B8BA9EAKA98888887867887ACDCBDCCCECCBFBBC696476775-A99998999999--229A998968826735EEE746368636754444443746I48555544454444343221111121112DFECAAAAAJGACA44655553423222---411----1----1--11-------------------------------1-1113416 1-------------1----1----1--11-----1------------112--2---1-111111-----------111-2-1------------1----1----1---2-2-111-1121111-13-211711131112-1111-1112-111--111---1--11--11-13131111I1113262D3-L5114--21 ------------------------------------1----------------------------------------------------------------------------------------------------1--1----1--------111---------------1-- * f.4.1 OMPA-like
[ 391] 44444444444444444344544455555565444444444444444555665444444444444354 2222322222222222222-243322222222522222322222222222222232222222332232222222222222224222222222222222222222222222222222222222222222222222222222222232232222222222332232222222222222222222222222222222222222222222222222222232222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222332222222222222222222222222222222222222222222222223222222222222222222223222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222322222222222223322222232222222222322222212222222222222222222222222223222222222222322222222222222222222222222222222222222232222222222222222222212222222222211211222222222222-22222222222222222232122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222223222222222222222222222232222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 66444562I76687644568666665755676665667777767765667677666756867545555357545586467555555777565455655555959B83776ABE78A454665A59D1L5DzA-77I5554666A85635274475968779A77776H78476969586y76568JKTa6IH5556556 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.55.4 Translational machinery components
[ 392] ------------------1-------------1----------------------------------- ----------------------------------------------------------------------------------------------------1---1------------------1----1----------------------------------1--------------------------------------------1-----------1----------------------------------------------------------------------------------------------------------------------------------1-------1--------1------------------------------------------------------------------1----------------------------11---11----------------------------------------------------------------------1--1----------------------------1------1----------------------------------------------------------------1-----------------------------------------------1----------------------------------------------------------------------1111-----111---11111----------------------------------------------------------------112-------------------------------------------------------1-111---1 ----UWF-1---D8H355596557778555555545555555555555666665447555454554454477555545555655552227B95C673233346ILX1U1SRxtgyooSVU*VpX**R*U**m7*k*SRXksQXdeMWVPOmkN*VZRaVAGOHFHDBYEHVAIKB------------1-4----4444- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.117.1 Ras GEF
[ 393] 11-121----------11------2--3-43----------------11-322-1111--2---2--- 227-92112221212-111-11--1211111-1-----31142D357-6651AB9-------21G14891184443CA2----1---1EFhT-B-----3M-92P6M-C----------------1----2----688651--3----1-----11-------1-3--1-------------42-1154-638111111---11-1--94BB3811-344-213222222-b11111111111111111111223-21-32-211--1211127-1122221111344233223322231111111111111222111222361-D8-------3-3E2--1212B-71-23411-----22---433A--3--C6333----1312-11--1-11---------------2--2-1111-1112322332112-5-1----------111111111332---1------------------------------16363-----222223-2222---32222-3-2---------111-----------1----------1------1--1--3------------1-1--------1F1----------------------------1141-G-16111---61--7766----6------1--------2213-45111-1-2-2--1-1122-1111-1------555552-111111111111111113--11111--122222222222----------------12111111-----1--1111111----2G--1111-1-2--2-5433111-1111---1-22222-------76666555------11-1--11---------------2----1------1-1-11----3-3262446-R23 11--219-QB-----KDNLLQTGQFPT55322212221111111118735PYflQPRMC9A8112211311-2-212213111211312416D7K-131-136-43-6G-AWSQTRRDBDBCHFmYCiA**H2ZKs8FBBPAFQD8CFB8NA9bEFBFI56B14423-221--43-572----86LIDLLF924E9EEA ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.67.2 Arabinanase/levansucrase/invertase
[ 394] 11-1-------------1-----1--------------------1111----2-1------------- 144-4------11147787-7133D59989975444324415-612-11-1-2211-1--422-9156661-----------3----------111----2---21-1-------------------------3-11112---3-12141121111---1--1-1-2231------------12-22--1--2333346432556546-433116461113223211-1-21-11111111111111111----1-------122111-1--1---11-------1---------------------------11---111--11---------------------------------1-------------2224113-----317452135243322212121222-34122323323173323327624656121-12424411311111111134-3-11---11-----11--------------1--111222132232446435111155232312247333854-2112242--434352-41--1-1--------1-2----2---11----221-1122212-1-1--4521-------------------------11--12--2132-1111112-111111--112---1---------21-2-3-1112122121-11111111111--11111-23321111-1--------------3---1111--211111111111---------1111-13-1---------------1121111----1241316424121211--1----1------11-----1---122-1-12-11--------33--11------------------------------------111-1------1-- 2287mw21OB64444CFNAPJLNXiZYCCAECEIJAED9DCCCCBDGLEWNQZdAFMLACDC528425133345473523346577346EMBF7EC68759549992AFCTJLGKILC9ACBEBPFDIBl*F-IFK9B9BFCEG96D89AG75LCHGBF9CC7E897KACO9ACD2732I43537E5C9N8I79KFEB7 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.86.1 eIF4e-like
[ 395] 11---111111111111111111-51132121--------------11----1-1111-11---1-21 1582811244511132222-22113A222223644458E92432762112139231131156819277D9311111112-3242111122411511---1611352816--------------2121111111212224422133623333222332222322324432222222222222252222211222333332321423222434462353223421-2222226311111111111111-111115----------------1---1-111---211111111111111111222222222222211111111142232345445552422322111132411111328516112242122212261253341111111H7A212624333344344444C-544437478D2-D778ABDGDDBE844437A744455775555555535553323-----------------------------134I338IG8ABAAC9C74444A9EB655644I6EBHGA1177A3561282F3FB363211266222222212234311126-13123441121111111244245411123112222111111111111111122651312625652333332E333324542471-2211211111134433645554544455-4555654545555555555898232353223232334233332644455543-45554555544411-21111111122135732322122222222244564572742498786CCB4A7955898222222222145582222273B55436555544433331111111111--------2----------1--------2--------121111111-541 ----321-32-24242667D665AD962223224664444444334566A9HVH776543231442471334342442235222313332C468347CA5132315-3F55133222111111124131241-11611212321111-112111-21133113533434AG13311524D3343131135332584544 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.79.1 YjgF-like
[ 396] 445443544444444445555557844754563-3334544443535732343244444444444--- 3333355666632655555-5533555555555555555533442334322-3434-3--33236453333-------2335422344111-----1---313324311---------------3333333334364474---3644344432333333333322333331111111111113333311-413555555453555555333325564232311333333355233333333333333333345-1-12-3---331321--11------111111111111111111111111111111111111111111146A64555555525244112444212446-254666588267744143113336334-11-1447447484434444444444444-8787997A854-5443334343635335364455556654444444443324554-----------------------------33333145555556565444445544444444544555434444444444444444442333332232222---553-576A575868555-5354538585555556644333333333-3222222254434335534323-3-25444434544445455465---1534------44443444444444444-4444444444444444444545442324444444444444444433344442-733343333444---2-----111132232212222222222222222222322332555645523443422221-1-1111-4444444454454442333334445----2232331111------------------------------------14411151113311 ----332-1---2333333445374944313333334333333333253345342435444411-111111-111122131212121--35333452111314554-3226475732332231476374CR626693433744533333373274533532G35453422649342432E1214554863443365641 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.57.1 Molybdenum cofactor biosynthesis proteins
[ 397] -------------------------51-1---311--1-----2-----1--11-------1------ -14-2--1----2-11111-1---2-1111121111--11---21-11-2--22121111----3--212--111---1111-11211421--2--1--3C12-733--1111111111----221111--111132212---2-112222-1-22-----1-3-1-12----2-----2--1-1--21--------------------13324------7-133111119112222222222222112212121-11--311111111---121---111111111211112111111212212222112212212122222311B141452187234431111322-2131-1231111-1--21111-63123----611A-34233-11-------1-1----1---2--5-3-4-1-55D-4-2----33---2333-32111--------3333111---1--111---2111111111111-2-12-1--2-27329WEGNKHaEEEEGCBKSRQQ7SQIDD8F6-182P51P--B231I1-121324G7--24--1112269211-1--41-31853314-44172-11-7x3312----2----12222222211-11--8681A5211-513233232111213-12142-1292321-1113I3E4761EBB1DAED9-F71F38A79FEFC33253A885EBffD3C557838776777559352546A4-3GGGLGGAELJL--2-1111112112-589111162111112251668655811186MOFKPCOA8CB88-GCC111111111266928B88B755332145444RUX22221111221111----1--111111121-1-1111-11111--1---1--1--12111-4-3 32231-2-2111111-1264436445121433413134243552-13227412A322353231-1-1--4112114111112134121341512621-12441-14-4-142733411524214661727M31834-23-213652224221123312623437171513133B6-21151222246A72322213253 1-12-----1-----1---------1112-1111-2-2-2-----------22--------------------------------------------------------------------------------------------112--------------------------- * b.106.1 Phage tail proteins
[ 398] 22-22323222222221221111321124322261114544422211116J791223-2--3331--- 4171452455533454544-42444444444492224788434643424331344424332232338445232224331--95333335524-------451114344311112111113333112111A11124122351115754212215322111121114122141111111111112-11144-4143333333433343334344453441113211444444332333333333333334334421113334131552233-11262333222----34422222222222-------------533652333-33--35555565-5-2166--12--314-41-3EK42-5221A---3--31522331-----115443445533611111111111-5213111143311331111511421311122211112112222222233423113111111111111111111111111111321123134333333334354444334355444343435352133312233213144353333333333333333411116651-13--2442-141222133111121-1333323333312422222223433333334243212233445432243444332442221333522222254763553333433333-33334333333331333335555643333343433433434445333333341333333333333221133333222133443665332-234334433323322222433333443333333353411111111131333333334564422222222223333311-111111--------1----------------------------11--2-22225-1 4222474-834-6738896677679684353445443554544567866786673357588A4435442333434431635333435439B585583646654476-466F4454765656462662D2Ia8-B6AA1249234654433632A3522612137342814314744656z44565B8PG6I864B5633 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.1.22 UROD/MetE-like
[ 399] 22-31-2222332322-322222232122343333333343333322344333234412113112-44 2332322322322223322-22222522222222222265233223311222212222--222323422222222222-221422222332222---111414432532--------------122333322323333432224242232222222332223222434322322222322223333322222222222222222222222222222222222122222223312222222222222223322------11--1---------111212-------222------------------------223222122-24-22111111121232221---3122-2322243222321232222--2124322311112523334232222222222222222-22422623242134442244324332642435323323422222222222224221111111111-2111111112111111112226227B8565666655333355663333-365876882266535354634366443222254243333323253222322232222222-434344333333325233222223223-1211111112223222222554538443355434343343443433-1-4422-11--143433344444444444-4434443445444334436343333435454555565555445332244442-333333333333111411111111124343111213-1111222244455444445266664555444545544212122121332333333343333444444444433442221442222-------------------1-----------------12-12-2222231 11--244-512132566648976DBC64555446555767666565557887C755686455755454445564554146656645454485655E556646467A-5779AGAD7A45546579A4B4N*8287G7546865545675795494A66A68E3623AB33B26643225k22222758G6873364334 ----------------1-----------------------------------------------------------------------------------1---------------------------------------------------------------------1-1-- * c.83.1 Aconitase iron-sulfur domain
[ 400] 11131322333333332221122244542444111111111113333324544122232334221322 2432512111111125533-34223533333457577476343343322222343432112242546564223333212323511111332213221--122313121211111111111111111-131211122222211142312111122111111111111111211111111111134533112-1122222222222223221111123211122122332322312232321233322311211232122122232222221222322222222222233222222222222222222222222222222222212222222222212142222222222233221222111221111111132313666544444746553446353444443444445-6766636657536555665786556434434634635434444444455553444222222221122222222221222211123556444643577767653444669766664567677652356543566445564454532364344444443355511213211--1111-222121123446466122333333333423222222222423324333344444254333443334443444441-12324-11-1134223333333333333-33333233333333333334443322343434343433443333333223322223223333222112323222333324434222222222311112333232333352445434463444444342222222222222333343333344365555444222221211133332222222221211111-111111111111111111112111111112342 2211446-943123444473333333333332343233333333433454574533444443444122242242422132244355132354455A54444444441374C7997657655362BB475Lj7-96F3543735864374454563755555757544323742832532O32344G5254464744647 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.18.1 Uracil-DNA glycosylase-like
[ 401] 11-11-11111111211321111112111311-111121111132222--111111----1111--12 1221323322223111111-1211121111112111123111122431211-212222--1115212444212222221-3112231134531211---1211111231211111111111111111122121312224311221332-1131111------11-2222--1-----1-1--2123376-42677777577577766795666867623324257676665532232332332222132223453265263349666573321133442221111211111111111111111111111111122222222232-4E6665666453661112125123-2112221222131323213-12124111111111112211112412112121211112-111113111321333635345565251112111111121--------1---13221111112111111111111111221111111111-211113332312111111121111-323212111111223112221211222----11---1---21113211111------111-232111131222212-111111222221-1-------1111211226111111111111112311111121111---2212------45113534776454544-554656445565655455498932233353334333333333362335554--322122211222--11111121111112--111111111111111222222112112----1-1--2111--1-212111111-2114222223434422211111112212--22111158111111111-2----1-1112-1122211111111-22321546551211 3554334-G68323345656544342523533326423443445555336767F5554635524446744335235323333333312226356553434573A55-394EAJB9BEB9D7AB7CJ7Z8z*J2OIU9AD8V79LD9F9AAD88KAFB9A37ABC49C8A4K45858666*66657HEWW3KE5465242 ---------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------- * d.162.1 LDH C-terminal domain-like
[ 402] -------1----------11111-22222332------1--1-1121211331----1---111--23 2242332333333342244-43224444545232223565333353323433665433223443469454411111113222343222324322221--242634343411111111111111133233533333433223332233433333333343333333333323324343333444333322233322222323223222333333322234323222222224322222222222222122223221232221212222222222222222222222222222222222222222222222222232222222222222222223322222222232323222222223222422222222222223433422222235662343345344444444443-54744546342366654585458753343326333323333333333333326332232222232111111111111111222233343234733777767666666677677766686456545447644344444444473222642222222333345452325242544432434643334333346234333335354724222222243346455437367243543333333333334233532-2342311111143444544444444454-444444444444444444444445684434444444444444344444444334344444544441143222222332133451113331333333334443444333436667476866554356633333333343334333333334433333333333333222233333311111111211----2-111-111---11111111121223222222423 11--232-411122344343434636244132222232222223334433533334443535222222222232222132222222322242423333352442221251C4556365545445533A4IZ4-57E75436446324443454B4945532635423433532544452F2233365683565352227 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * c.65.1 Formyltransferase
[ 403] --1----1------------1----111---11-1---11111--1--1-113--------------- 1-1-2--------111-11-1-1111111111---------312-1------11---1---21-21-221---------------1-111------1--11-2---1------------1-112------1--1-----1---1----321-----------1-22--1--1-----1-----2----------------1---------------1-------1111--------1------------------------------------------------1--------------------------1----------1---111-1-----1-23------1----1-1--11--21----------1--11---1--1-1--221--1------------------------------12-1----11------------------------1----12---11-------111-----------1--1--------111111-------21-31-1--121-1---111-1-----11---1------1---------1--1---2--1-1-1212--1--11--1----24-1------------1--------------1----1----------112-----1--1-2-------------------1----1--------1----------11-11----21--------------1---------------11111111111--1-21111111-------------1------------1----1-1--1----------11----------11---11--1-----------1111-111--13--1122-------------1-1---12-------1---------111---1--1-- H8355AN-*JFCIGS66886966655B778686A767869A449A8686597BC6788AE6D7224451344623451248334544567F96B87FAFBCA2756286G*BHMMIZIFIFGOKcmBSK**PDhNyGIEGMHHRDALBFDZGEiIVDFOT**SNLGINGN*ADYP2FMD*42233EA7779C3ANTOPK -----------------------------------1-----------------------------------------------------------1--------------------------------------------------------------------------1---- * e.35.1 Membrane penetration protein mu1
[ 404] -------------------------------2-1---------1------11---------------- --1------------1-----------------------------1------------------1---1-------------------------------1-----21-----------11112-------------------------11------------1--1-------------------------1444443261534353----32544---3-1--------3-----------------------------1--------111--11----------------------------1-------1----111-------------1-1-111-111------------1-------------1-------------------1-----1111111111-1-----1----1--1-----1-----------1----1-------------------------------------------------------------1----111---1--11--------1---------------------------------------------------------------------1----------------------------------------1---------------1----------------1---------------------------------------------------------------------------------------------1------------------------------11113-21111121-------------1-----------1-----------------1--------------------------------------------------------- 2-----7-----33733335454756544333334533333333323335456433334433333232-42232422-3223333322245435454444464676--2-*******dacWbnb*qY*f***-*m*NeVd*Yl*oMjaVMpQK*clcgf6AAF*I*25114--92-1--1---2--2213-----238- -------------11---------------------------111------------------------------------1-1----1-1----------------------------------------11----------------------------1--------2---- * b.22.1 TNF-like
[ 405] -------11121111-1--1----1-----1----11--------1------1-21122211----2- --1-2--1111-------------1------11------1-11---------------------1-1-1--1--------1------------2112--11---511---------1111111-1--1-----1--11-----1-1-11--1----2-------1-321---1--------------------11111-----11-13-1---1--2---1-1----1----1-----------------------12--2----11-1----1-----------1-----------------------------1-1----21--------212-1--11----111---122-1-1-1--1----72-1---2-------------------------1------1--------11---------1-----------------------------------1-1---------2------1-11--1---1-------------------------------------------------11-------1---------1-1---1---131211--1---------------------111-1------1-1---------------1--12---1--3331------------11--11------------811--------------------------------1---111----------------1----------11----1-------1---------2-1-----1-----------2223221-----1121--111----1--2-----------211-----211----1111111111-1--1---11----------1------------------1-------------1-211---- 2456DBA-K8A576D63755647D997658677857573625344368755C67573466694459543464657652665443875564753C4E66475E4CBE49MNoaipvdjPKJLOQN*mJmJ**VBxU*JLQKfNNaMJPOLJjLInOfPQW8OOPOKJCRGCZCEIA6496eA5676INKi5YB987NGEF -------1-----------------------------1----------------------------------------------------------------1------------------------------------------------------------------------ * a.207.1 Formin homology 2 domain (FH2 domain)
[ 406] ------------BC--------------1--------------------1------------1----1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------- 3312945-765376768855986675655357576985665655866666545599686656664565167457864-454456464556C68548645665499826B5*WbfaeeROSOKOU*lU*O**s8lb*YLRHRUOgVQPQKKbNR*UQdfaDGRPWVGCQLeUAIH53354*64444HBBD8A84234225 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.41.10 Zn-finger domain of Sec23/24
[ 407] 112-11111111111111121332233313211--322212131164854E81-2222342111---1 ----3A77BBED6A1-1----1---3----------4E46-41456547A72A624482256-8I954AV6--------1222-----32221222----11111122-----------111--13122111223144231138-6-2222-11--------42-1561-------------3442222-169FFHFHDEF8GEGGGEBBCBBBGGG577C866444444JI5AAAAAAABAAAAAA755775-1----2---43-1--2-----2224443333122444444444443333333333333322222222233B56AAAA9BA5C73522286745131621-2EC2--31222322215241-211233133221--236654744444444444C-32122333422-9BB9673697757312124K959832-22222222-332--53------------------------------11112333234555754555544335555456331112--1111221181412211111-1622222222--1111-6722212323111----1---34111141341253-33332-1-1111111211--22695261112211244121421141234422---1121------I6994B9799C7BBC75-8795B9C5A78DA777775BBCEE9977577777777777777C66A77783-BBCBBBBABBBB--3-----------1B8G555575--1222--52233211-465146244635745221466---------1988799999C8D6611---------------111------------5-2----------------------99B1221122222-121 --------2--1----1------------------1-------------1--------1----------------------111-1----3-1----------1-1--------1---11-1--21-1--1--11-1-1-1--111-1--21-1--1------1--1----------------1-1113---------- ---------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------- * f.22.1 ABC transporter involved in vitamin B12 uptake, BtuC
[ 408] ------------------------2--1-1-1------------------------------------ 112-111111111111111-11111211111111111111111111111111111111111111111111111111111111------11111111----1-11211111111111111111111-1-11---1111111111111111111--111------111--111-11111-1111111----111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111-1-----1-1121111111111-11112111111111111111--1-1-11-11111111111111111111111111111-1111111121-121111111111111--1121111111111111111-11-1---111--11111111-1111111-111-------1-111111111211111111111111111111111111111111--111---1111211111111111--11111111------1----11111111111111111-------------------------1111-11111111111112-111111111111---1--1------11111111111111111-1111111111111111111111111111111111111111111111111111-111121111121--1111111-1-1111--1111111111111111111111111111111111111111111111111-111-1111111111111111111111111111--11111111-----------------1---1-----1-1--1-------------1--- 3334DBD-G7535564555555554655555565555555455555655555575555555545554535565456636655555566636455455555454CAB2FR8HkXXjbQJLMFJNLrpKgP**eBqQ*EKJIZJNYKAMJIGTIBjKNLKOBEMFAAG6HDBG89EB3667l77666IGGJ5NB99A999D ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.45.1 ArfGap/RecO-like zinc finger
[ 409] ------------------------11131111111-------12211211212--------111--11 2221211111111111111-11111111111111112142143611111111211121111111114212111111111121111111221111111111111111112111111111111111111111111212222211121333333333332223223332545322222222222211111111111222221221211111211111122111111111111222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221321111111211118822221121112211112223111122111141131113111111111211111111111111111111111122111111211111211111111111111111111111111111111121122222222222222122222222222222113121222222222222222222322222222342222222233232243232232322222222322221112231211111111112111111112119989B512111111111111111111111111122232111312222222232222222222223111212222222224222213333323232-33443223223233333332222322232323233333232222332223311222222222222111211111111121212222222222222222222321322222222233432222223331111111111332322222222222112121111111122211111112222222221111111-111111111111111111111111111111111 3333A561KA8344555336566656555455666655555455555555555747566556776666569976CDB69B8666667765A6575E8665544ABG37DMBFKHDEC999B697JF7O9o*D1FDN7696J7AC99A678A76N8A8AC7DJ6DAA9P6-759665797*56587OORY5KE58BCFG7 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * b.130.1 Heat shock protein 70kD (HSP70), peptide-binding domain
[ 410] 22212343444444443222222132223242111111111111121122222144443444445112 3332522222222422222-22222222222222222222232222222322222222222222222222221222222222322222434424332--222222223422222222222222322222222222333222223334222232222222222221353222222222222223333344322255555455555555433443355422242332222223322222222222222232232222222222222222222222222222222222222222222222222222222222222222222222234445333333343444333444533333343233352343323343432322222222222322332222322233333333333-22222222232233333332333322222332333322322222222222222332222222222222212223222222222222222122223333333334443333444432434333322333223333222332242222422222222222212223222322234432222222222444423222222222222222222222222222222222222322222222222222222222222-2222222222243323322221222222-22222222222222222222432233222222222222222223222222222322222222222112222222343322423222222222222222222222222222322224342333223233222222222522333333343332222222222222222222222222222222233332222-222222222222222222244444544442322 3333553-A334445333323334343224333433221222222253435455443333334332322331333331333333332223733342333432244426F6A9I97A88665777CD7C7R*91BAI6777B669757686878DACA7549E56576858636374565V56545A5A86695565656 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.67.1 ThrRS/AlaRS common domain
[ 411] 54526A4ABECCB89552554668E67FGHAF212352472733333423754242539232224-22 52A-42-24224--123DF-F1----DDBEG-2---1349254422-1-3442--2-1----442-23521-211562-2442-141-2121-2------2-21-1221-------1------1227989-1A26---331--3-AAD3B9923344232438D2T8DK44553322424321221-11-1113333343233233331111-1223443-132-1112112-11-1--1--111---22-11-1-12------1--11-21231-1-111---1--1221421112111-----11------121-121113212-222222212-1321-1----1-1-22131372811523333212---1B883-B61D2274B9484C45F33233233238-85789DAA888-888579BEHF7B3G1153494454-1-323333335792124A--------------44-15-----------1733--3414855758433226634644445966347A--58425453885314--821-1-223--11-B13A23134426852656452536843E484222343--111111111121434443441--12112765-221221358623242232621432---93-D------55B93A46BA56655B62B66BB77AACC776666657A979DR87589A786968B8AA88887B77731566656546743--A11211-211-12332333132342324542314311-11-7225527668763442882-----1---1644475875232534222335-216242--5-4454LL--------6--------------1------11----1-1---1----1-- 5-----------2---1---------1---111-----1--1----FB--1-----13-------1---------------------1-21-1---2--3--1--1----2-1--1----11------------------------------1--------1-1--1-----1211--14----12--3-----11-21 -----1-1------1--11-------------------------------1--1-----2--------------------------------------------1---------------------------------------------------------------------- * a.43.1 Ribbon-helix-helix
[ 412] 11-1111111111111-1111111311331321111112211126232123232-1-111-1----11 1532F33766523444444-483358444445A888EAED29397H764344DB834622BBA284C8B8221113111-11422222654412222--262229BC36222222222222221111111111113892111171822533323333333233333435133233333232322311---123333335652343534232244333232453432222244333333333333333434352131111211132441121322131322221112112222222222211111111111113332222112111332222323233213322222133114211331111311111-1-22413122222222335663335344433333333334-558697665B3255539A69885834242143232234222222222111133311112211111--1111-12---11-21221225222333254453444444446355553564645552256334433545343223242332222222222226541214111211111132312422165687812111111111-123233324411111113333432233324334224222532334242-2553422-22232222322342222222-3222322222323222222533322342222222222242223222222223222222222222233222222234334344433322223333322233445332323244445534444332443223232222234442223233433222323322232222222771244--------1-211111------21---1-1221222221222-2222524 1111112-411-3442333466484753433344334414343444533443665533532224223312322232222222222233447333A4334342445434429534423211112155141EX32A571-2-6-1531122161452233431257452714623633442U43523834A4766956256 ---1---------------1-1-------------111-1-------------------------------------------------------------------------------------------------------------1----------1---1-----1-1-- * c.71.1 Dihydrofolate reductase-like
[ 413] -----------------1-------------------------------------------------- -1----------------------------------------------------------------1---------------------------------------------------------------------------1------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21--846-2---667333116224223473324173151313513352255957434215363252521554424573673457522124DB35852245154673-872t**rw*jWXLIXgT**MxX**z7*s*PeQOwVlrbKcUQFpTI*XpaabANENODFLqPYaKOA8-231I3121-267534-2-11222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.217.1 SAND domain-like
[ 414] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 51BK--4-3--------------------------------------------------------------------------------------------------9--***r**pcYUXbqc*vNrR***M*m*TbccySmqiNhRXQzXS*d*msi**iLcKE9PC9ULOFG---1-1-21---------1IHQ*- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.5.1 Midkine
[ 415] 22213111111111111211111143342344223222222222323212332222233431111-22 3343344444434242444-64334444444444444444355543524444445443334444444555322222223222421122222222221--222222222222222222222222222222422244333332224155443452244333333445344453332333332332323334423233332333333333422222233334312224444444322222222222222222222222233222222222222222211113333333222222222222223333333333333233222333233133333333323344554222334223223422456332233343222332233322222234332223333444444443443-333333432422333333333333222223334333322333333332442232311----------111111111111111-122432223332222222222222222222222234223222222422222323322232343222222222233223233233333333332546444564333344333222122222222222222222234333254343232344544343354333333331-23223-1-11133332423444334333-43343434434344434442433323243444444444444443332332332344444444434222222222222233322333223223212332333333323324222233332433433333333333334344455555545453333333333333322322222221111111-113----1-1-1-111---1111-----33333232222212 2223333-83123323333344543443333334533333333322122222221232222233333333443334535433332344424333332322233334235398676654455443883838c5-74B3644744744544544364755637G27334333743434233f3324464773644535333 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.129.2 Phosphoglucomutase, C-terminal domain
[ 416] 33123223433344231333343213312313112224222321312134443522143221113-23 2432432233222223323-2233222222222222222243332233222233332322442242234422222222222224222222222222211322222422322222222222222222222222222222221112232323222322222322222234522232222222232222222123333333333343333344333344433353333333334533333333333333333333412111131113322112222223333333333333333333333333333333333333353443233344533233333343332333333336224334533453423344454122223222222223222342232222222222222224-2222222223225222222332222222222223322222222222222222322221111111111111111111111111112222223443233333344555332255564334223232233522233544352224232232222222222322223222333423333244522245244334544222222222222223232222222222222232232222222232322232222322312223322122232222225555545466-454644454544455555422222353234222424442422426546656212222222222222222222223233424342222232222222222223222222224535256343224243322222222223333333333334322222222222222222233332211111111311------------------1-2----11211213222222 341133516113335346327456384446545454343423432422345466433744352312341333333243233-23332423B3494652322413252477B65764A4323454A65B4MgA1B8G442574565556549544348454224B455734734A32433c23234C6464594334343 --------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------- * d.68.2 EPT/RTPC-like
[ 417] ---1111211111111-12----131122111111111111111111111112211122111111111 4B5-41-1-----121111-11--12111111----4392--221211-1--1121-1--11114--3111--------212-22222655512222--342447758A111111112122222426534455441--1----214432223-11111111112216686121211111211--111111--3111111-1-----1-1-221-1-1--121--1--1-123-11121121111111---1-2---11-----22---1---------11111-2-111111111111121111211121-1-22--------11-11112111-1--1---1223---13-2316621211122--1-121745633324344452232--1321344334443454-333223354234466545455556344445477555555333333334332412422222222----221122222222211112363423332375565533333446B334334773367211635353334554664647644434343343444546476336443C6654457847A74897D9E5542412122122212212121131222554422322323432333234444233342132-345341--22143345524335456544-344334444435444444355554558444444444444444453333333322344434333432423222122222123242322332222222343343325222444454755668676446412211221223335444445457933436333433333125-223333--------1------------1---------1-----1--1111111734 23--3181512625712411211435111441233234344452211222343313331222454632233245463-4445454532446525493244222655-354C9IAAA954964B5E66B5H*91AAI447394857555255546174659E895542557-33571754r6543478B92724273651 -----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------- * a.102.3 Chondroitin AC/alginate lyase
[ 418] 11-1-13555555553-212111231122153-1111111111----1111121111-1112211-11 5353541222221286433-3311573333336585A8MO241937221322AB9343--54913494A511111111----6-11--22211111---1333442423---------------11-112111115454411136-211221----------11111121-------1----3332411-51122222242442322243331124215714111111115421111111111111122221-------2---222211---11------------------------------------------------12--1----------1211---------2---1331-1-113212212--2-2E554-1--146IEF2148566555555554554-33C44C47D66-B66A77A98A55A98445993233388--------442-3522-----------------------------31CY4-FC95AFGIGEA68884DDJDA99929KEX9OFD25BB8BBA74DAG4JD452----211111111---3892211-1-1-22111111111111-222237-12--1111111--11111111--11111112311224312333333243432321324---121-------32221212331211135-3515212522315552555556225516463656666656536743144451-144466646666---3-----11111134A---1-------1--44444422123937777664C2678723441111111111122222222223252244444333-------1----11--------------------------------------1--------312 ---1333-421-4226764C885ICE93333553457444444333646AADKJ7786444621312111222131111122223212132373333222215332-2C67463232221124154242CQ6-535232143442112-13-25555265533756543472353323271111244674332365345 --------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------- * d.177.1 FAH
[ 419] 22-122111111111111111111111----1-------------1--1111121111111-111-12 123141211111-111133-3211223333322111222223132331211221-211111-423324631----1-1--122212221211-1111--32---4132-222121254477771121-2-21211233341125162241111211111112131243211111111111111-22211-1-1111111111111113112221111332111111113221-222222222222211112111-11111112112211-2-------2221----1------------1111111111111---111----211121111111-1-12111111121-1335-3--122112111111221113222312112213333323343422222222222-331342323441222222222222232423222223122222222221211254111111112121111111111111111111-111221222122222232222223222222232223231-22312311-12-32113311221-----1-21323314312122111112121233335211216524111-12112111--------11313111112212323122222214222223533451--232411-11123122212222222222-23222322222223323322321211233333335333454321222222311111111111111111211111111112622111121111112111---1--2112324444323343323322211111111113112111112322324433334432223113211--22--------3---1-1---------------------111111111122-- 3411752-82222355386367765654456552243333244456635689A833354122131312222222322222233323-13273374A21111-23231BHLxONNEUFCEDDDHEOGCSC**I3RIXKFEFMGEEEEGFFEH9EREGFFQKMDBFF54O99618DM1361722213985D78V45BAED4 ---1---------------1-1--------------11-1------------------------------------------------------------------------------------------------------------1---------------1---------- * c.50.1 Macro domain-like
[ 420] ---12------------------22111-111---1--1111112-2311312-1-1111-------- 1541----------1------1---1--------------21-1221-111-543-------2-2---111---------2-2-11111124-2-----1423353513------------------23211-6246624---11A6C87714444------595299E5------------1-------121--1-111111111111111111111321122111111421-------------------1---------------------------------------------------------------------42128222222212121221---315--121B1227357212111131--6296555-----2178A2336A59A------------55748858124-3112333333222-5334317677344--------1221-H5A------------------------------1-222422226335567222244984355254579BAB--987F4645A6874478A7676L4-------6635AK7E64429D8MODDD3C7CC798577788AB311232-11111111111111164232--E93BFF84876967798A7B995AA995BC--54488------65546446666666666-6646666655666556555556446536556666666666666556465663-645465556665--5533333222329P4E111111-1--1111155555146835DHGIGCKCGCBAC99DCE---------49989BBBBBABCCBBC97A777BA6666--X25511322333233321-----------1--------------3112211111-5-1 ----113-2-1-11113413223313144122212323332212221121214311311233212112112221112112112111-1126136522212131123-3113213231111-1262-134493--22-3-13--33-311-2--2133-6---13-322-2----1-211111122646L2821174441 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1- * a.24.10 Histidine-containing phosphotransfer domain, HPT domain
[ 421] -------------------------------------------------------------------- ------11111---------------------1----1--------1-------1--------1-------------------------------1---13221311-1---------------11-11-1111166655---5562212121-11111111132-111-1111111111111------1-33333333453535743A-77525533325244PNQQRN512--------------1---1123-311--2-11--431--4-12221111111111111111111111111-111111111-1111111111211----1--2-148--17871-41-3--133313241332332---11-2111114434--332---1212134444343445-22122122342-65444456543522321-21353311311111111-2212112-------------------------------14-11----2222221111111211111112221-3111--111-1121211-11--211111111121---11113511-2--11----111111111----1--11--1-1111111-11111121111111111333211111111121111111211111-----12------11111111111111-11-1111111111111111111111111111111111111111111111111111-111111111111---2-----1-11113-1111111111111111111111111112111111111111111111111111111122111111222111111111222------1---1111--------1-1-------------------------------1------2 ----45C-1-1-AAA4444564347435526457565322223343446445345634756634242312433623232322331263346144676353123854-B-4WSTKXgTHEBCITKxoEqG**j6zbz8LEIcEOTMENGCGkBAyEPMOK56J6FB86UDEG47C7---1------61425-1-2----- --------------------------------------------------------------------------------------------------1-----------1---------------------------------------------------------------- * b.34.11 Prokaryotic SH3-related domain
[ 422] 11111112211112211-211111111111111111111111111111111212121111111111-- -12-21-----1-11------3--12------322221542-111211-11-52221---211-2122212-----------1--1-1--1----------1----1-----------1---------1------1--22---312122--322--2---1211-23434--------1---21--------1-------------1-----1-----1-1---------12----------------1------------------------------------------------------------------11----------111--1---1-------1--1-----2-11-1--------1-----------111-11--11-----11-23222221222-11-11-2-131-222---21-112-2-2-1111-11311--------1-----11------------11---1-11-11-11-----1--2---112212111111113111111111221211121133-12122132--2------1111111--1311---1-------------11----1-----11-1112-22222----------1-111------2--1---1123311-122212--2-1---1--11-----11-11--1---1---11--111---1-1---1-1111111---1-----------------1-------------------------------221--221---------------222221-11-2322222221322223222-----------11-1111111111---------------11-----111111111111-1------------------1-1-----------1-1--- 3322121-512143245857886A88766555522377777875765435ADFE98933443434222-31244321-12233333123362564534223532342472GLN*OK*75**5S8**f*8**D-JP*AAFqp56F71D*J*H74*5T4Zi32414B34231535514632T1113687AH4D321776B2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.30.2 Amine oxidase catalytic domain
[ 423] -------1-------1-------1---1-4--------------2-----21---1------------ -41--------------------------------------31113---------------------213----------2-------2231----1------1-1525--------------------------1--13---4-1---11------------1-2211-------------1-----------------------------------1-1----------1---------------------------------------------------11----11-------1----------------------------1111111-1--1---11-----------11-----------------41--------1------------11111111-1--21212------------------------------------------------------------11---------------------1-------------2222----443231---1-------1--1------1-------------------1-1--1-------1------2-------11-1AA--------------------------------2-1--111-----12-----1-22--2--------------------1221111111-1-1111221-11111111------14-1---11111-1111-1-1--1111--111111111111---------------1------1--1111---1------------------3-11--------------------------11232-------11-------2-331121-----------------------------------------------221 6813FCQ-XBF8ABI65FB579793B5AA9A788468676756787EC78MGCHEEMA5DAA545322133423432133356532131E985G4K66546G7TcM19Wk*NCGNGFJHBDFFGIFKfGl*G4ULNBGEGLIFDGAGLIDBG9MHGFDFRRTLlC98B7BB44MAHYRDsB9ADF*Vd*A**E9GEBBB -----------------------------------------------------------------------------------------------------------------------------------------1--1-------------111------------------ * b.69.1 Galactose oxidase, central domain
[ 424] 11111111111111111122111132233443---1------------1111111111211---3-11 244-522222211221122-2211222222212222243322221111111122212111221332244431222133--1121-111334313222--3543475334--------------1111111111212222211131634222111---111-121-23431-1-1-11111-1-111111-1211111111111111112233231113221212111111-1111111111111111112111111121121211111511111121222211-111111111111111121111111112121111111111-111-1-11112122111211131411223-1111111141-111-1--31711111111111213--11111111111111111-1111-111222-122223344222122113322333322--------------11--------------------------------111----------111111111-1111-1-1-12-2--22311---1------1-11--1-11-1111--12-13441-222121222-3231332344444552211111111111-----------1-1--112344224333435322233333323323--12111------11111111112122221-1212122211121221222111113321111111111111111122111121-111111111111---4-----111122411---111-1111-11133333332231311111111111111222----------22242222222222433434433433331---544455--------11-----1--------------------22122222223613 D94686D1M11487B799868677776556667678596886765457889888777688787783443544547343444666767765D798887688457CB819GDKGGDHGGCDA9CE9IFAPCg*H-JDN9D99EDEIE5DCBCEB8FBFECBAE9AAD96E98A78C65GGB*987BEMHLP8TFFC789AD --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * f.51.1 Rhomboid-like
[ 425] -------------------------------------------------------1----1------- ---11113111111111----21111-----111112121-22112122-----1-111133-112111111-1121112121-11--1111-1--1--1--1211111---------------11111111111111--11----11---11-211-1112-2-1111111-111-11--1------1-1-11111121111111111111-1111---1-11-111----1--1111-1111-11---2-1----1-----11--1---1--1-2----1---1--1----1--111112212-12--1-----------11--1111211-11112--1---1-1-1-1--1--11-1-1-1---1-----1----------------------------------1----3------------------------1-------------------------------------------------------------------------------------------------------1---1--1-----------------1--------2--------1-1112--1---21-1------------------------------1---------------1----------------------------------------------------------------------------------------------------------------------------------1---1-1--------------1111-11-2--1-----------------------------------------------------------------------------------------11121--------- 1233GIO-933-99D33546897787877689A87878777686558944548535686A9943535312225535535542322365579A3BAH5868465CA81C*6TSYOSfNOMIGJQNziGkH**Z4tZ*GJFDZHPZJ8MIDFSDImGOJMKCE6*HEA6W9LH68T97EIN*ABAICBADF5DCWTBFCAN -------------------------------------------------------------------------------1--------------------------1------------------1--------11--------------------------------------- * a.140.2 SAP domain
[ 426] ----2--------------------------------------------------------------- -----1---------------------------------------------------------------------------------------------------------------------------------------1------------11------1------1--------------------------------------1--------------------------1-11-11---11-11---------------------------------------------------------------------------------------------------------------------------------1------------------------------1----------1---------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------12----------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3*--11C-XEC7ABD22-22111121111122111111112211112112212111211212-1-11--1-----11-12111221---13221211111112112-15AlAHGHFaSMQNTVYfdT*Q**TAhVySSQRgNUWHPUUPLnGK*PaJOMMx*GFG9CEAB*32IG1DFE*212328--22-915GIIHH ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.126.1 Serum albumin-like
[ 427] 222-2-1--------12-22111111112-1411-1--111-11-111-1422-11111121111--1 1212222222222222244-42222343444222222232254421221111222222112222222222211111111123111111222211111111111111111333333323333333111111111113222211112323222222222222212223323222222222222211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111112215232111221111111113211211111237453332222211111111111122332311351131114344415522111112312321211111111222111121111111111111111111111111111112112111111423334211112212222223225122111541-2111121212121111222111111111123111111111112121111111111122222232111111111111111111111111111111111111132111111111111111111111111111111111111111111111211-1111211111111111111111111111111111111111111111111111111111111111111111111111113111111111111111111111111111112111111111111111111111111111111112222212122111121111111111111111111111111111111111-------11-----11-----1111111111-211 4A77AE96OAC787766794555644766666667654444535467666657646666455665665356267545355655545668888678A87787B59BD64HHJ8B67BAD9CBBBBFG9V2T*I-EEMB59AJA8E99CAA8989G98997DKJ7A879I57D7CH9DCC8*98889SOWW8PF9A7B97D --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * c.8.5 GroEL apical domain-like
[ 428] 11--1---------------2---1--1-11------------13112--41----1---------11 DIz23-21222-2----11-13----------1234--2231-117212--247B-----3223315B752----2---------1--7666-222---5333FA6B2D-------11------------1--1-3443922165952232411111121111414432111111112111111------512444444331226532--2222332111-2-1-------D-1--------1113-1---1--------------------------121-222---33354234343-----------------------1-131----------212--3513-3--21--21-1-11-1-22113---F-D1111---1----211111---------------------2--1-2-111121212111111-3-1---11--111111111-111-11-------------1---113-1-11--------1---22-1F7767B312224426333322862454112234282--21621-1113-221--------432974-2----2-1323321-4-2134--22125I-1-----------------1------1-----4443112-11-11113---11243122---22-2--------22------1-213--1-----1--1--2----------22--31111-11222312111-------------------------2------221235-1---1111----1--3231-32----1433434224252222242-111111111---311111-111-1-222221111111--11441122--------21------------3--------12---1----2-2--1746 331155A193C197495A9BDF6C7AC6643478665525444446769DGEHFBCACA9DB3434585324552CB-MCA44333677B8859D95244474358-7E4iECKLMKFBEAGGAPVANE**H2LGbEIHBOEGIHBFC88SC9MGECCG29C77751794425BB1A35I53596847A7C7312556F -------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------2-- * b.68.1 Sialidases
[ 429] -----------------------12------------------------------------------- ------------------------1----------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------11-2------------------------------------------------------------------------------------------------------------------------------------1---1----------------------------------------------------------11-1---------------------------------11----------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------1--------1--1--------------------------------------------1-111--------11---------------------------------------------------------------------------1------------------------------------1----------------1---------------------------------------------------------------------------------1------ 221134718333334575645444545444655444444444444336444454557344455555663554555663575455676664647439567425465224B2eqmm*jqSUSSQYU*yJ*U**h2*T*TQPOkSTYSOXTXRuRL*VtWaYBE*WEKBBYBGaFNVC3787*57444944645555798B8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.278.1 GINS helical bundle-like
[ 430] 222222222222222322222222--------222-----------1-22123222222222222222 2223334333333333333-33333333333333333334333233332333333333333333333333323332223212223232221222112222112111121111111111122222111111111212222222212323411233333333323232333423122223221232211331122222222222222222222222222222223222222223111111111111111111112----------------1-----11111111111111111111111-1111111111111111111111126211111111121223221222112222113233222323332232122232222211111222222222222222222222222-22222232222222223222322222222222222222222222222233222221111111111222222322223221122112222222222222222222222222222222322333323223322221122312232232232222222222223311122121122221232323232333322312111111111111111121121121223232323333333333333333433333341-2333222222233334333333233333-3323433333333333333333223333333113111333333333333333233333333333312232222233332332233323333433333322222222223233332222222223222233333333133332223233333323434333332231121111111111111111111112---------------------12111111211222 4366657-947487844514445776544343366744544343334444547634444545663543444344533343444345755473475556644865632635E99795886756669B7C6IyC1ADE7867C68A859866A66B667778A57E6767687A7C64589*78856778F3CB87A7761 ----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.101.1 Ribonuclease PH domain 2-like
[ 431] -------------------------------------------------------------------- -----1------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1-------------------------------------------------------11-----------------------------------------2-3---1---1-1---------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------1-------------1---------------------4-------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-11------------------------------------------------------------1------------------- 1222--G-1--------------------1-11----------------1-1----------1--------------------------------1------1------C*mnchyfRQQQQWQeaMgP**e2lXwNPSQVNSVQGOPUFSMN*RhRV********3NnZ347*---------------------1--- -----1------------------1----------------------------------------------------------------------------------1------------------------------------------------------------------- * d.171.1 Fibrinogen C-terminal domain-like
[ 432] --1----232523322-11422-51--12-42------11----1-------1----1---1-2---- --2351-2---2-19fQ66-6I--HW66666BIHNI6JWo-b3d1--2----442226--12B135E7735-111----1617-----1--1-11-----2---3--121----------------1--------66687---33------------------1---1-------1--1--11-122---12----------------11-------22433--1-----4--------------------1-2------221--21115----------3-------------------------1-----111---111--22--222222212-13-------1---1----87-1--1-2------1-2--733A-----3-MCE1-9B7AC833442443442-34A33E39856-411112321432964728592224268222222225111-823--1---------------------------67F9-6uaHfGDDFJH5577799GH887868W8UTemd36785748BCO9JAPT567---121-------2-2922-121-----3-----12--3----122121-8---------------------11----2--1114-3--1----2-1----1-11-111--111-------1-2-41-3443333333-2333333333233223221111---121211111111111111122333321---------------1-111111111-2313111------------443242422222556547663424552a3---------1---21111111212114----DGI------2-111111--------1----------------------------2---------1-- ----111---2211375856555A9B8332322632566666655443787DGD66B444334-112-------1------221-1-1-55458553113233545-283926235233433535B263Bd4-7444343723442324232571633B36922362945H1224-13-----1123194421713241 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.123.1 CoA-transferase family III (CaiB/BaiF)
[ 433] --1-11-----------------12332-21132--1111111-1-1---21--1311323---1--- 1----111111122------------------1------1------111------11------1-1-------------435-1-1--1131-4--1-------1113-1111111111111111--1-11-------------------------111111---------11111111111---------124454555444545543544124441--33121223211122221222222222113321---------------111----------------1-111111--11-------------------------431-22212224152---411-25-21152-----3--321-11--12--1----1-------1-1----------------------1--1---11---------------121------------------------1-----1-------------------------1-1--1111--------------------------111--------11---2---------333322222-1----122211-2--211111-21--121--1------5524333334332222222-1-11--33123144231-1111--2---12122124----111--------------------------------------------------1-----------------------------------------112111-1-1112333332122222232221111111111-------11-311--2111-212-2212234434444433433-----------------5112211--------11-------1------------------11-11-------1- 31-1-11-5--1--132311---233333223311--------543-1--5848344211323131-1112-11----1--1-121-1-14-2-223111--3----275*ov**hdKJILNOJbWFaN**Q2XLjFIJGdKKVI9JJFESEBYIPPLRm**OtiVQlJSkNJVP---181---1-11-31-4222111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.54.1 SNF-like
[ 434] -------------------------------------------11-8--1313-------------1- 1-2-1--1---------22-23--1122222-3333-111----12------121-------1-1-1-24--------------------81--------1-3721478--------------1----------------111--22432214422----1-22146652------------333----------------------------------------------1-----------------------------------------------------------------1-------------------------1------1------------------------11---------------2-1-111-----12322---11111----------1-11-11-1--21-111121111111---4142-111132-111111111111--1-------------------------------42-2-1------------------1------1---2----11--11111111---1----------------------1------1-------1---121---------------------------------------2-4---1-------------------------------------1----------1--1----1----1-------------------1------1-1---1--------1----------------------------1----------------------222---------1----------------------2-----1-1--1111111111--------11-------1--1---------------------------------------1113 11----T-1---5678BD74453383355654555553232332335578DDCDGG697875543334335334333333332332444FCABIAA98AB78AOFV-9A-zUURZcqMKG8NMMcVOiMk*O8kOoJNKEaJOMMEOLEGQHIdLPVOG42C37T*7*DHH65J-1UMCB8B8WBJUq*7ZHC5223-4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.118.1 FAS1 domain
[ 435] 11----1----------1---1-------1-----1----11-2-1--111-1-46746563----13 2253332333333343322-24224422222444443787234332222222544345--3-82339423242222222342323222332222333--24225453-6-------11-----2333223232333553411153356344733333332333452634642432552434462233232224999998A7678876833334687623253323222224A22222222222222223334456444454446644564452445562233222222222222222222222222222222233222333235524333333322233334222362223222234234425634482323131877B32332229593333344433323333338144245534332466644373473522321455232253C222222222242245----11--------1----1------2-3124465445522C7765C7433355EI44442487E7B95325495473273968652432335222222223232343563232363-22225353333245655662725723333334252222222253323322312244-2232222424222432474242-3-1-122122242866252222222222-2222442222222222222333673346466666666666666622242423222422222222212234434443343322422222223332222255555452622332233766435532532333333233-465533333334341-11111-------12222244322222222253-1-1---1-1---1---1-11-----255331511113-2 -1--32--7631111112-1121312422----3---111111---11341535------1--1--3--122122-1-331---1-21213111212221132312--52112121--------11-1-261-321-22--121--11-1---1---1515616211-23-1-1211-1a223216446-2---22121 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.78.2 Aspartate/glutamate racemase
[ 436] ------------------------1------------------------------------------- ----------------------------------------------------------------1-------------------------------------------------------------------------------------------------1------1-------------------------------------------------------------------------------------------------------------------------------------1---------------------1---------------1111---------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------1------------------------------------------------11----------------------------------------------------1---------1--------------------------------------------------------------------------------------------------11-------1-------------------------------------------------------------------1---------------------------------------------------------------------------- 1111--L-1---11111111111111111221111121111221111112112122211222--1---------------------------1----------1---32-*upo*jZTRSOVYWkkO*W**e2xVzCSRVhTWZXLVVPLXIJvTQQUdi*kd**52612416*d2giI*1217-FLJb1DU-1----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.12.1 Lipase/lipooxygenase domain (PLAT/LH2 domain)
[ 437] 34837323444433444434533995679598427242434544356445979277677562215-44 2311221111111142234-52116233333321113167231222212111111211--2221223323321113332142312111224412------221111122111111111111111334442334-2222342225131121111111-----111--112-------------3341233232133333333333333323321133412262533333324333333333334434322224211121111211111111121111114443422211444333344332222222322222111342111222633333222242423221333413242432244452233352122311225311222212324344233322222222222223-2121132234126443443355653211221342443431111111112212634-------1---------------------1133212222533333222222223524222344534652244443464633442429212111-------14121432432432264433-533243543223237541------------1-2----1211222231222222232222332222222223223--21343------22322223222322323-2333322323223333332232342122222232222232222222322221-211111111111--132112211114233111111-1211211111111111111254445232263223322211111111133223333332244423221222221111--5333222211111111111----2--11-12111112111-22144553363351321 1123311-EB3687754314651-3-122153443341-12-132156224133333--2-1321-2313-12--11--21--11-12273349642436-724332296I8C398C5566987JE6J4MvD3E7V3623F2AF83A874I64I565DA33699257B6649G61-243J3131-45321A2343245- ---1-----------------1--------------1-------------------------------------------------------------------1---------------------------------------------------------------------- * a.7.12 PhoU-like
[ 438] -----14232222222-57873334--34646-122211----341321443531---11------42 3341532333332366744-4511744444436555447545542231411134533311446143555451111111121133151211223111----3132554-311111111111111358546366514-----111424334445344433333353335453353533353533443331114234444444444454442243434444323-11-111--332111111111111111112--1--------------------------------------------------------------------2314A333333373814444675334111221577C641-34A1113113144444411111545762225335644444444444244344343463-555444544476564434543434544555555551333373311------11----11--1------111113544333334856887588886688888876889466414446544444444545549464342454345113454-558756896788714351655623353343441-1-11111121111111154156116254444143433333443333434444443---7441--33355441554444444444-442544444444434444457557334555555555555555554444444314444544145552321------1--4644633331311111111144444443444488886897679776766111111111154454444466555221242211111116531442233-11-----11------------1------1------1111111111333- 2121-11-21321-1212322222322--1-421--11211111-121321234414121221-1-1--111----1-----------11311243-12-1-12---1732-11-----1---12-13-4A1111311-11-22-1112-----21122---1211-121---212555V43453B5692644741115 -----1-------------------------------------------1----------------------------------------------------------------------------------------------------------------------------- * d.134.1 Nitrite and sulphite reductase 4Fe-4S domain-like
[ 439] 11-2121-1111111343111218111121-1347332311119B598453431322-2241--51-- 231--121---1-122133-33--6233333433243526111111--111-1111-1--1111111111111111111124311222434425111--26-74253-2-111111-1-1111-532357116233321-3341334213322133343323222244541432221422221211133411-111112111111121------11122111-1------1111111111--111111111-11--11-11--11111121----111111-111111-----------111111111111--11---11112345A5555555A5947555ABC676533325199842322452232331231622411111315444213332211111111112-651383521231211222443322364526133233-2211111111231-131211-11111---1-1111-11-1--11-11-231413233454444435545665544445469655672465337386455633634342223222222324346419967485456666367664658A56656486-21-21111211--------321-411232-6322-234444425654433647632--23534------21-12212221222322-2323322224222222222323221--3343333333233333222222221-111111111111---2111113444251-1-------------1-4233422446313333232273344332211111111142222111111122244333333332222-155212111--------21--------------------------32124323331321 -12----1712--1-13422353-3132111-1213-11--11-2-236492312214--1121-111113-21-3212211112--1221-31316444113-12-28-BJHGAHB6675696KG4F9e*E4IBP7B75G8A98556C3D31N9567513185417D58A15335656U5744377CC2874333111 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------1-------- * g.41.5 Rubredoxin-like
[ 440] 111-11111111111211-11--1-11111-112111-----12311312232-1212-1211----1 2221322222222132222-22222322222222223223143622322222222222114322434444322222221233------4433-3112--1222111311---------------1-1111112-2---11---11111-111----------1-111121------------324-------11111111111111111-1111111---11--11111112111111111111111111111111111-11111--111-111-111-----4---------------2334311212231-----------11131111111313-211233321-1--11--1111--------11-413-4333538326333333223333322222222222-22223323233-333333333444443334544444334333333334333445311122222----11111111111112222143442244423111135111111152342221243523-1218112111111312121311213463333---11112423-21-1211--3322333332232432111-------1----------1---111333443343333433433333333333333--1-2-3------33455433335344333-3333333333323333333343458733333333333333333533333333-357756556555--22111111111333334444345333333652222233222335555594635555375422222222223333333333333364634333346536--1-332222--------2-4-1--------------------------1------2222 3333665-B321864237844334844335645565564655643333445555559654345444553343746332343444223342533233343312579715O3GADAEGJ8C59799HA7B9Q*D1GFN77C8E58I599797CC7R5G9BD55668666C78B34753521Q25124E9CC7E83456755 -----------------------------------------------------------------------------------------------------------1------------------------------------------------------------------- * a.60.8 HRDC-like
[ 441] 11-1--1111111121-122222144433353121111111111111211112111--11-111--11 2112453444343354445-4333454444443333445625263333343353333422333445747541222211-13-32222244531411-111434343432-------111----333333353334222231115253543342233333333433245633333333433332222221-334444444643464454225534444333444433334342333333233333333332331------2-1-21----2-112133311121113112222222222211222111111112--333---122-13----------111111112-3-122112443112--222112-1122222221----222213222221133243333332-22222522222-2222222322222222211422222232222222212212123-----------------------------2222222333323333342222322333342442222232222222222222233323233342222222212122313323122232322-132222223322245222122-22222223222422322222225432242223333333333333343433331-12232-1---164453624455455544-4444455455456444446445648634444454445444444544433342-5666665565652212221124443223333333333333342343334323222346766433533234233222222222223445444446545544332333223222322-222222111-1---21------------1---------------11-1-1212533 33-21-3-3-1322235564454976A2222323333756676233663456443433456523432213224333212335543245344454544322244333-18376544AD455566264854BU6-73933444355235613443623326-1437141123511653333U53453979B2D333A6445 --1--------------------------1--------------------------------------------------------------------------------------1-------------------------------------------1-------------- * d.161.1 ADC synthase
[ 442] 22---1----------12------322223323222222322222222-----122211222122-22 2221443444425354455-5444555555555555554434435443343433454433445644444443333333222212222244222422---23222222221-------11-112-22222222222222221112211111111111111111221112121111121111112222222323344444444444444432332444434343354444444223333333333333233333322233212322122333322222223333333322333333333333333333333333233222333322344222222232322332222222224221222222222222222322221233221111222222223333311111111111-22222222123122222211111122141121111111122222222222222232212222222---------------222212355221112433434222222222222232232353412222312223242223331221322222222222121362321123222222323322232333323222222222222222333333322223212222221233122333224322122321322-2221111-11133333323333333333-333333333333333333333333222333333333433333333333333223333333333332212222223344232223223222232222222222223222232222322222222133222222222222222343332233211222222221212222122223311121-1-2-1----2------------13------2-222222221123 2211223-A44-2323542122232433223332334333244342334442232232223223222313214134688924422322246255343322331424-2317DB99H75456566674M6b*D-DBJ4564A576625546653F6636649I61333622535832122a2222151263343668757 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.1.5 Inosine monophosphate dehydrogenase (IMPDH)
[ 443] ---1111111111111121111112--1121221--------112131--1111121---1111--11 7971533233333332244-421152444442222244433446222322323332231133735344453222242311133323227556-4111--352424233211111112121111444254434434222443343336765345343434423422334452222221222132123311211422323343333434335333333332273333222223333333333332233333333323233223233433333443322334332222222222222222222222222222222232442222313112222222213111221111111122111222622121112211131333733622222333353343445533343333334-75766C67442-544776799A56324335353533344333333333222256211111111111111111221111111-11-474323444466665555455553655552446443552233323534367364341342355222223243344314634344287445333454636224527745223223333321111112113232332222342332222322223232322342234--34222------34324343554334433-5333443333533333333444223432312222222222222433533341-233333333333--13111113533345333332221111132224444435222426666466554553543521111221152222333332222234453554442222--62333344111111-111-----1----11--111----1----32223222222732 11--111-843---2121221112321111111221111111211112131434121111111111111111121-1111111112-1-11122221111111111-18614222-42111211551138H7-62D122361221-111-311424325-2-241-2--1-7D413543g22242EAJM1A6212-1-1 ------------------------------------------------------------------------------------------1------------------------------------------------------------------------1----------- * c.129.1 MCP/YpsA-like
[ 444] ----------1-------------1----11------------11111-111---------111---- 3344433333343343333-333336333333333344664556333342233452343333434336774233333344444333233333333331-4335433342333333334433333333333333334444411144332244332223333333133334333333333333332222333679BCECFEFF7FDEGGD579998EFG665565434443465455554544555545323535434554543422335544344444444424444333333333334311111111111113333334442576B6444444454664765777656245562466454343246665233322544321232233213322211322222222222-1111221212433333222232332133333333333344444444463333344331-1111-1334444443443333323234433433334444444566665555666645445335433433543334434324333232332222222222442234343343333333232333223223244223333333333333333333333343552222222222322322332222222222231-3222212111142224332333223222-3232223233322222222444232224444444544434344422232322232222222222222222222233332222233322232222322234333334342333433333233332333332323323323242222233342343333333433334343333333444343334221111--222122121212212122233233333333544 -------1--------11-----1------1--1--1---------1------1-1--1------------------------1---1----12-------1------1-2----111---------2-131-------------1------------------------1--11111161-2124112-21-11-1-1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.175.1 Penicillin binding protein dimerisation domain
[ 445] 112-1-------------------111---2-------------11---12-1-1111112------1 -12-12213332312--11-11--1211111-12221364-1-21121-111355331--11--216122-1---21--232-1-1--1112-3111--13213412222222222222222221----1---11-----------112111--11--1------12322-1-----1----122-----1256686756757777774255547754365422------41322222222222222332254-1-11-2111121112211------11111112---1111-11---1111111221111122111222--24155555555656-311544423-74-2---2122-2-3--112--323-133341111131953---2111-----------1-3364383512-232211132111142111--3------121222222-22112-122312111111112111121111112124-224314----C9979B445532258545534533356512445113224213421111111351111111111--3--5-2--1233---2111-1-1-22212311-12332333331-----1---12-1-1-772322331325888956B777676B8697---2---------74445544555454444-5434544454545444445666663326755666666566656444354441-6444544454551111-----343312-232221211222211128888838223424454567826689343222222222214559454437566533444443333333---711111122212111321----1-1-2--------3------------------3-2 -----11-31-11131312133--21-114112-11-2131221--112211222321------2-11---------------1-1--114234132133-12314-173BLUKMGE8967AE8NM4HAO*A-DBO7968CAACA48988973H8BG8E59D4HB32544D87C5-412A---2341132357-HAHI- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.49.1 Proton glutamate symport protein
[ 446] ------------------------------------------------1-1----------------- -1-------------------------------111---2---------11-------------1-----------------------------------2---A---1-----------------1-----------1---1--------1-----------------------------------2-------------------------------------------1----------------------------------------------------------------------------------------------1----------1--------------------------------------221---------------------------------------------------------33-------1----------------1----------------------------------1----------------------1--1---------------------2--------------------1------1------------------------321----------------------------1----2----3------------------------------------2------------------------------------------------------------------644444444445---------------2----------------------------4-------------1--------------2141222-----------------------------------------------------------------------------1-- 1--2473-21-------1--------211-1-111-1-1----233--1221-211211----11----1-1------------1-1--11---12-----1-1-2-2A8D*****qYPQWcnT*oU*R**q1wa*ZZca*eevUUkTOLpUS*Z*QX*32--142171161321---1-111---C5b-FH1-12321 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-- * b.11.1 gamma-Crystallin-like
[ 447] 22222211---1--11221111122222222211222-22222112122-22234332222-111-22 2121111111121211111-111111111111221212231-1-11112111111111--111211211211111111----1-1---112111111--151111-111--------------21----11--1----42---1111----1-2--2111111--1-1-212-----2------------111222222221222222112213231111-11133312223---------------11-11111221221111111111-111121211111111221111111111111111111111111111111111-3111--------------1-----21-1--213211211--1112-1122--1111-1--1112122121221311111111111-11111111111-11121213321121132---111112-111111112----12211------11----1---------------22211-1---11111111111111111111111-1111--111-----------11-1--21-222222211---1--22112213-11111111232-13223-1222212-111112-2-----1111-2111----21-122------1111--11-212111-1--21--------1-----------------------------------1-1---1----------------1---111-1--111-1111--1--2111111-22--1-1-1111-1---111-------------1-----2141212121423---------21212-----2121-334-3-1---------1111--111111-11------------1-1-1------1-1---211-2-1---111- 1122375-E46234152455344644222144433423231222113723454314234655243335233255323333377455331464266313137633763AJ7*QLSSTOEBCBFEGVSGeG**W7bNeBIIGIDHOG9CBDAJHFQFOLGG6AGCBGFABBBU97A64C65*734CBQcM*5VM548627B ----------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------- * e.28.1 Reovirus inner layer core protein p3
[ 448] 22423222322222222222222211112121112222222221211112322222233222222-11 2221322333322222222-22222222222232222232123222222222222222112232322222121222222222221111223212221--222324222222222222222222222322222223222222222322222222222333333222222223333333333332322222233233333333333333334222233333342221111113211111111111111121111311122121212222222112212121112111111111111111111111111111111122111222122223333332323222222222222222222222222222222222121312333333333333334333433333333333334-4333333353323334444434334333333233333333333333333333333111111111111111111111111111112343333333333343333333333333334333334333333433333333334333333333333333233334332322232222222322222223222223522222322222221111111112222233434433344434444346444444444444--33333------44444445444545455-45555455554455555544444445444444444444444444443334521444444444444--13111112222344352221112111121123333333222333333333333333433311111111144544444445444433334333332222223133222211121222312----1---1--------11------22222222222222 3422455-A352334223274423323222222222222223243323243464223332322223232223222232322332322221422323222312333323B43284447322234322473HV61A5A2222533421322322272633532248254354823533465X655638A8E3974533236 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.51.4 ITPase-like
[ 449] ----1-------------11111-2----12-------------1-21-3411----12-----2-5- -1--1------1---------1--1--------------------11-----1-1--1------1111-11----111--1----1-1--1---------------211--------------2---1-1------11--111---121---1111---------22121---------------11111--1-------------1---11-----1---2-------1---11111111111111--------------1-1--------------1--1-------------------------------11---1-1-21----------2-1-111----224--2---1111----11---1---11-------1-------1---1--1-----------------------------1--121111-1-1-------------------11--1------------1---------------------1----------------------------1--1-1-------------2----1-------11----------1--1------------------1----1-2A-----------1----1--------------1-------------------1---1------------------1-------------------------------------1------------1--------------------------------------------1------------------1--1-1--1-1-----21-------1--------------1-11111--2-------------------------------------------------------1------------1------- ----1---3--1311-1-23--3-1--1111--122112112243312-13233-113--1-211-2-22-1-232---211--1--1--1-113---21-1---1-16HKZgfRi*XTWbbpc*wZ*U**k-xe*QdVUsWV*eYYdQWkXN*SZVVSA85H8AChiRgFFK44145-5--1314B4F1F11312111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * e.1.1 Serpins
[ 450] -------1---------------1411121--------------22-1716A2----1---------- ---16-1-321---11111-11--211222212111-55315-C241111--2411----753-7-55121-111-----2---11-1111--11-1---41---24-1--------------568469645A15111-----4-*hhgdbMGHAA655666LKJQdisY474444474444--1-------222423433-43343321--12333---312211122168----------------1111122-------122----1-1---111---------------------------------------------22593333333733131--22111--------112----1---------2-29AA8------43-2---1112-------------12215322113-2221111212112-128421----1------------1-14E1333333343344773377766465433331121---42-C1111--37BBB--1-BBBB-7-11------1-1-1---14--H--111----------------11241-4----16----1-2-5262211--5l41------1-----------------1--23--121-1192111112411112143141---4-1----------12-12CB-4---53-924661-655B2A331542-----7--2312333434223223531143323--44444424654--21222222222--2-3---11---------1------11--52322213122111-1211----------1313-----1223311--------------K-111122--------11---1-----1-----------1-----------------1 931-684-A34---2D1-------1---11111---1213123----------------111-------1--2------------2----2-1-----11----21-2*HU958B962434353C54F7KhA3A963273435633432444273843P4447AP633122-2h-4559*56643D97N-CA43----2 -----------------------------------------------------1----------------------------------------1-------------------------------------------------------------------------------- * b.80.8 Pentapeptide repeat-like
[ 451] -----------------------23333-322---2--222234C-5I-2424-2-2122-------- 2523------------------------------------6---6---3-----------113-3---------------1---3333-------------------2-------------------------4-36656---23DAFAFF24455------677-66E7--------------1-----243--2-22222222222343343222433433322222232--------------------------------------1---------------------------------------------------C546B444444444463554---43C--44383445327526233883--85-B779-----229BE3327B22D------------5565575B23--5339776777663-5-3-2-888825---------2552-89A------------------------------2333352222555555C666655666668385639999--555D5555725B55AB85569A9-------7432AA7B55638A7PHAAB5KINEEFIACJJKJMA524333-3333335555555556839---B9-B8B4444-8999986688878966799--23668------33332332222222222-2212222222222222223---3322233333333333333332-2-22221-322222222222---3---------33J28---------------222221222229CCBBCCCHBCCCC8HHH---------76667EEEEE776AA98ABBBB9AB3333--E57744545555555533--------------------------3-33333333-5-- ----------------1-------1-------------------------------------------------------------------1---------1------1-------------------4A1-3------------------------4-----1--------1------------115-21--1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.40.7 CheW-like
[ 452] -----------------1111--1222223221111111111311111111111-----------122 1121333444422222222-2211222222223222425413333233222322232222232253562522111211221122222222231212-112232432334----------11-1122222223222233331114242222221122222222222212212222222222222222221-3245555555545555553344445553352322333333322333332333333333323311-11112-1-11--11-2-1112222222333211322223222232222222222222211222111123234111122222221224222112-22112233211111222112-11222333411111334333233343233343333226-44544534363-6445454354653325345565664452222222222213135-----111--111111111111111-1--23222345554555456733334453444434534433322335332222335623323323222222222333345225333432353332122232222443423232333322222322222222222222222243232232222222223222232332331114333------22442222222222222-2222222222222222222222443432222222222222222222222222-22322232322222-2111112222333322221321222222223332332222232222223222222222222212222231222222223222232322222222212332-222222----------1-------------------------12121111112223 111-223-85433335687755669753433343435443533333456997E97644435442224243322233313423343322336563553234435559-5C324422542242232A52728a4-55A2242544312421141292314436133343122A33314563X33464G9CCAE97872634 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.17.1 D-aminoacid aminotransferase-like PLP-dependent enzymes
[ 453] -------11111111----1---2-11---11--1211----------2-1111-------------- -13-262222425212233-37--4232334-412236592-11-321413-64722311136352336322-113222---41321121223---11--1-1-1143-----------------1-1-422-1133333---1395544444455323122246757551311--12-11-43231--1123444443445434433356675543235134624462543466777767777667423358A14751266BHJ336832857232354A544444444455555435444444444444445566364541316B999A979273-C2222332121-612312-141233133211-1421-666521221222544332332266656565653-53733533314-222222322234413-22212-2223122222222-221-34211-------1--2-11-13-21111---1-66451233346666668456655455555465572453113222432222423122332113121-1---31-442212112-43-222--51412142-4425351-------------11111111--1-1226I7533553446566655775565555644--1325111-12135543635445555555-4556455545454555556978554336366766655666666444355554-5333333333331-222222212111263223352333332333422-12-11213277765656354555546---1-----22225655657553556256552223222--154444552222222114-----6--111211111115131---2222213221--22 ----1---21---1-1--211334142-----------111-1-----433222--112222-----------1------1--------3---711111-----1---22B1212-2---1-----13-883--1----1------------------1----12--2---211-1-111111--91-2-221-1---- -1--------------------------1------------------------------------------1--1----------------------------------1--1-------------------------------------------------------------- * b.84.3 Duplicated hybrid motif
[ 454] 113-2121212233152----111211121231111111111121212--1---22211221----62 4521441111211111112-1211211121211315344314222112132133212111134321135412111211124152-2--3447-3111--113222111211111111121111111111211111455341-252G356334211211122142117A53-1-----2--1-56433222722222222522233223232222222322222263343363333333333333333222228222222262222333222211133322321312112222232323232222233152122111111111273243333444334533333211462213A42433313421132521-12238115112153494D9A8532222222222222B-4A747C36D861688EC6698A664G141956B88B452333333332533184111-11111111111111121111114-5615BB4333127657676E4444BB894544575F7486A1297C2A5988C55653A81122111222231332714147323132123331122511313665431-3111111111112211211111111133333142111211245521121211411111--24223------32-13632563233951-413551211243144244185731123221122113259331552332-13--255515435611---133313242253412----1-12--1-2111123212111113455332A21122143111111111115245222223424353527343333223--G14444D522232222311-1------------------------1--------2221 ----231---2123-1-2--23-1-----------11------1---111--1-----1111111111112111112122111111111-----1-111111-112---23555A273222243A6272CN3294631226153745311422522235112--261314---42-221-1111121-71321-1333- --------------11------1---1--1--1-----1--1---------------------------1-------------------------1-----------1-------1---1-1-----1----------1-------1---1-1----------1----------- * d.268.1 ParB/Sulfiredoxin
[ 455] ----------------------------------------------------------1--------- 359--------------------------------------211-------------1----------------------11--11-39BC9-C23---3623191A68--------------43443424343312243-----544244411223236431211CAE1131232222222-------22-11111122111112211-2211121111--1-------31-1111111111111112212------------------2-1---------------------------------------1---------31245---1-1----1-661--2-1--1--23-4414221-12--14---96L933621111A9CD9A33B886644544455557-4965797D264-94459B2B9C26763324164-423245555555538963B771111111111----11-2-------1-11312C-466336ADDCC69677788A986673CFBC887E-245642332A432524554546841111-1153476632643-42545334152133366459685755A-21211111-33222222243126AB3346569-725377773785676647A6781--4115------869C6567668778787-86767887868877777775C76B3644555455555545454956457752-633455534555--1144232677842659112221112111112676665423162AA8BF9EB5BDDE846655442442546A786444448A78BD897985552322--G-11--11--------2-------------------------------------AD6- ----------------1-------------------------------------------------1------1------------------1-----------------2---1------------1--1----------------------------11-12--1------21-------------7-----7---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.46.1 HlyD-like secretion proteins
[ 456] 22323343444444336334433143331432112222222222322222232233333231112-11 34824---------24311-121143111112243543711412222-111-224---11-153413443-1111-111-1-2222221133-1-----12-222-2-2---------------111121112112223311122-12-222--1111112221-12113-2-----211--1213322-322224242332353335334433333122131122222216--------------------2-1-12-1---33114511112----2311111-11322333222221111111111111111---111151-14111111111123--113-412--111111221112123111521-1133112-----3188A-112133-22222221224-21522425-75-7223447544774224145231345122222222264313122--------11--2-111222211211-11-1251-22224567875344435588454434B385475-3553212--3-6467112-224---------11-131-112-111222111-1111222111111232111111-1---1111111111211-2223132122-33-1---1-1-1112--1-1-2----1-2------63441356446666566-46465666564775555559A7452116466666667656565545444554-355555546666-------------2222622221311312333211-11-3---4244444665137411464-11111111-1--1111211111211313111121111--11331111--------2--------1--11--111--1111---2122233333-61- ----321-36-11226796633486544566563333333333333543449D612513222233323131141222111233343225--472221121422324-193E88979B5563686LK5G5XxG1IAH5674B577646756865D6765735135354839669741-21-1111431168551321216 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.74.1 AraD/HMP-PK domain-like
[ 457] ---1-111-------------1-21--2121-1111121121122232122221-1-----222--11 2322222222222222222-2222222222222222222233223222222222222222322222222222222222212122222244542422-111312112111---------------2224322332222233444224232222222222322223222234222222222222332332233333333334333343333333333333333433333333432222222222222222222233-222322322222223222222222222222222222222222221222222222212222222222244233111222132354333333414113223244253233433334222223323222222222222222222233333333333-22222222322233333333333322322232222222322222222422222232222222222---------------222222222144444333333333333333333333334333324333222334324222432222222222222222222342322232232222222332222443422342322222222212111111122322223333332233322222223222222222222-1222222122233333333333333333-3333333333333333333333333334333433433343432333333333233333333333322223333322222233322222322222222322222222222322222322322222222222222222233333333333333442222222222222232333333111-1---1-1-------------------------22422343332332 11--323-41213333332454434333333433334333333344333344443333333333333333334334424433334434337333373343331555-3B1A475354445334454352Da5-5553323314542443344333942434735424434C33733343f3223243783433574444 -----------------------1-----------------------------------------------------------------------------------------------------------------------------------------------1------- * c.24.1 Methylglyoxal synthase-like
[ 458] 2-11112222222222122212112222213111111-1111123221-1322-32332341212-11 1262422222223136622-24114622222444442233-111112212223232-21132113233531111111111213111113333-4221--1212121221111111111111111221131112322332311122223222111111111111113222211111111111111111222222555554542554455342232645235452222222253222222222222222222223223233222222223312123233311221222222222222222222222222222222322222222131234445455242251133331121131222883311224311112212111112-121-112111111122133443442447-111111218G-1988443767576321122775455455111111111--11111111111111111-1--1-1--1111111141232112222333333111113325212112344142211111-21111121231111111311111111111111233233331232222333232432112121321111111111111111111111-1111122422534334222233522224254245--12111------52422413333333333-33333333333333333332322211223222222222222223333222221435345435444---1-----1111115622221111111-11113222412111112232232125334111111111111121111111112221112323223332222111211111111111111111-1111-111111111111111111113211131111111 1111343-732143357535452656466555545435444445445545647824544444443333344334333333322244233574754444533337771354L664549244445485484Jq5-8523323634624442252274353359746464559D65A32352O3322345544571244654 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.55.2 Creatinase/prolidase N-terminal domain
[ 459] 11232222222222222122322222222222233221111112222233333122222122323211 4442634444432455656-552255555555555555553635965645456655452254645466664111111111224111111142121111112121312231111111111111121111112121122122222223232332322222222322222222222322222322222221112222222222222222223222222222222222222222332222222222222222222222222222322222222222222233222222222222222222222222222222222222222222221121111111111112211211131212221424423333233221111241322222222222222322222222222222221212222222222222222222222222222222222222222222222222222122222122221111212222222122122222223222222222222222222222222322232222222222223322222222222222222212222222232221212223222222233332222244443221111111111111111111111111133222223222332222222222222222222212222211111133223333333333333-23333333333333333323334322232333333333333323333333321222222222222111211111222222322222222222222222122222222222222222222222232222222222222322222222122223233333222333322221112111111111111222222-222222222222222222221111111111323 1111112-5223224333433332322223243333133333333333333433333334323342221421323431332334333334633342423332253612A175443324375444AE295Df6-56I235745574153515345255261-213322211222223564i33345E54A3742411113 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * a.156.1 S13-like H2TH domain
[ 460] -------1-111111--------1---1----121---11111111111--1--------------22 1221411-----2-2----------3-------1111211-21122111221342123--2411112323-2222222---11-------1--1------1--1111-2-------1------121-11------11121----11-111-1--11--21--11-3112-----------1-431----1--3222222321223222112211222121112122232211111111111111111111133231221111166113344422155433331123113333333333323223222322323331113333---311111111212---1222211-11---1-21-1----2-211--2-2-2111----1-312113111-2--11111111111-1221231122--122-2212322311-1-11122221-1111111111331------1--111----------------------1-32--11-12222221222222322222222231112--331-----1-1-2--1--12-2---------------1-1---1-11111-1-11-----111122-1-1----------1------------112221--1--11-111---1111111121-1--1----1--11132121322222222242-2222232222223222223655123212222222222222212222222231-311111111111------------------332212123131--1111111----2-22222332-22221113111111111-222312222333331111111---1111--1111221111111111--1----1-1-1111111112121-----------1--12-- 22--534-C53-333AA97665985A72242223222222222221CB7C576855611212331222125214155234111111--1843A23811126C633314C2IEMEJIFBA8ACEDLICOGi*G-MHN7CEBF9EDE8EAD9EB5ECGAGJ546FNIABG98O8DC2133-212-A7RZ**7hK42UNba4 -----------------11------------------------------------------------------------------------------------------------------------------------------------------------------------ * f.19.1 Aquaporin-like
[ 461] 11122222433334222221123323322212221111232222112324444223222321211-11 2122222233321223345-4322434444443333223334232336222244322111332122424422111222222222222222221133---1412122232---------------22222232222233332223232332222322111111332232321121111111212222232123233333334333334333333233332342336445534523233322322233232222312222221213333221212112222222222322333333333334444434344444221333222313144545345335323553333323223442244344122522222122221222321111213332122123211111111112-22222223241142232223332234211214434343333333333333232321111111111----11-------------112132234425334332222244323333333533443115332132235223122111113122222221-2122132211112321111323233341333362353223111111121222221234221222241111222321111221121211112111-122221--11133223322333232322-22223332322332222242222222222222222222222222223333221322222222222--1122222222222231211122212---1123343334343213333333422223222222222222211112222222233343444453332222112111111113211111121----1-111111111121211-11112122212222312 1111232-41424343223223242433244332322223332322325122322242422222223212232432212222233512153224623334322255-24486677B51662774B8344Ga6-4363336325621344451153646548D36343E38327762432K4243323565462222234 -------1-----------2---------------11-------------------------------------------------------------------------------------------------------------------------------2-----1---- * c.1.17 Nicotinate/Quinolinate PRTase C-terminal domain-like
[ 462] ---------------1--------------1------------------------------------- 566-111111111111111-12112211111111111111231212211111111111111111122223112221112133143433232223323--333242135222222222222222244333432433222231212223412221111111111111143331111111111115224411412244444444244445422443354322315323333333212222222222222222222221133122232211331122221322222222222233223223223333333333333222222222235223222222222244111332422223452125122324423333112353333343334343533333433344444444443-22333323434333333333333333343533434444333333333333433333333333333333444335333334333313353334444444453433333345333333435444454444544544333343344443344433333434344475433444444444566636543556694443343333332334333333333334233342443333333333334333333333332-3333431-33344333333443332333-433333333343333333333333333333333333333333333333333313333333333331133333333333334333333333333333333333333333443333434334444343333333333334333333333433333334333333333224312222222112212221111-1-2111-2111111111-11123322333233142 21-1-1--11211--212121-111--11111112--1---1--1131331-2131-1-1--1--1-1131-2-111-----21----2--11-1-3--2--1--1-1-191532--112124274154DQ81528-542723221124-31133623311-2613-4--226-32-22A222-152773311113-31 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * a.223.1 Triger factor/SurA peptide-binding domain-like
[ 463] ---1---1-------221-----1------1213-2-----1-89-5D-27531--1X7-1224---- 7AR-2--1---------11-1-----11111--------------2---1-------1--241----21----------1111-----****-*BA1--S*NZQ*N*Q*---------------11-313-11M322222---A1--1-1--22--------2--A212-------1------1-2-4311-1-----7131131882122232146----2-251165542--------------------3-2-11-----11---1--1-1-1------1-1---3----2--3---111--12221111------------3-------------------1-42131---1111-111---------Q-5-11-------------------------------1-1--11-------------------13-1---1------------------11---------------------------------1--------------------2-2222----11111---11-----1----1-11-1--1---------------5-21--21-------H-2324-12162OR-5---------------------------2----24122221112--1111-32-1-1------1--------1--1-11993131511-9114149254C431-2321-----------111-2211-3-12-32-2121-----------------1-----------11----------------11111-1----5------1------------------------11111--111-11---------------331121--------11--------------------------121--32323-4-6 ----114---------1------------------------------1--------1------1----------------------------1-1--------11--651WSIHLLEEAA9ADCMKAG5N*I3FDUBCBCF9EDEBFBB9E8BMAIG7E38D236B4S64O44B6-2--111---2113-14-1-1--1 -----------------------------------------------------------------------------------------------------------------------------------------1--1----1--------111------------------ * b.3.2 Carboxypeptidase regulatory domain-like
[ 464] -------------------1-----------------------1---2-1111-------------11 4372F33333322243333-3333333333333333344425431112121134332311A713426A53111111111111111111111122112--16132A3426111111111111111331351111111113311131422222222222112222237236211222222222211111223-2333333535935355314223133721153121111116323333333333333313311211111111113511111111111111112131233222222222221111111111111111111111131156333353312142661111214311221133611311112214111213211111111533131113711113333133331-3353433332115335331313313424121311111321111111113113212111121111111111111111111111111112111111223343336777335377753A435413211125313313111451111211311111111113113-4411113321111133311151322-255111231111111111111111111111113521232112233333533333333333331-1111111111162665435667577555-655566555565545555634444344666666656656566545555555114333333333331111333332222247272222222222-2222656862411142332322222222222432222222221111333333313332212222332222211111111111111111111112111-1111111---11111111111111212221311 111233--211-4362233644486745354233445555555444334434433342333344444434414333535544434444325226552446164542-47244222322322243853324H3-33521233233343132531313233222232-3222-4424133453323546483761176653 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.150.1 4'-phosphopantetheinyl transferase
[ 465] -------------------------------------------------------------------- -----22-224-2------------------------------------111-22--------3-----2-2---222----------------------------------------------------------------------------------------------------------------16C6969A68AC96666AMCKKMG8766861847NQSTOR8428887887888888863345H6--EK--8-7HI--CN-264333424669979878B99979B7A58666666666666658822-888B-5-BYCCCEAAEAA8-k--2222-2-2-9-3-----2--2---GFB--11-----------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------21-----------------------------------------6585-723116366652-1333466531161333333787AB222747657787874846663213333--611111111111---------------------411-1111-111---------------------------------------132----------------------------1-----------------------------------3-------------------- ----------1-121--------------------11---------1------4---------------------1---1-11-------1-------------------21-22119I993kHpWAvL**v3YSfEHA9d9F*V9PKA8NA22---2111---1-----2--1------------111-3-------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.142.1 PTS-regulatory domain, PRD
[ 466] 1111-11111111111-1111114322222222243333333343214669A8412112221112-22 3334535444523244444-4544544444444444445544442232422323323222445245555442111222211222234222323322---1212233313222222222222222333433333331111133621233333333333333333333443633343333343333343221233333333343343334433332333544412112221134211111111111111111121-11--11-1-1111--1--1--111111111111111111111111111111111111111122-1111361343333333131343331112231131146EJ533333683333322254333311112343333333333233333333333144444644342-43333343334434333333444444333333333244344232223233422---111-31----1-212123343333333333333323333335333333434334323333443333333433333444232222222333333158633333323322322434244332323422111222222222222222233243224532232123323332322444423424221-12334------22423212222222332-2222332222223222222422221123222343342243323221223231122222222222211132112211114323221123312322122253446232223344643343333332333233334333223322223222322333333333322221221333333-------121-1-1--------1------1------31133333333332 23--221-411-11221412111212122112122112222222221111112312211111111211111212111-1111111111113211232211121224-3615131121231211153163ER6-43913233111112211412212211--61321------1122332S2224242492433444432 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.1.21 Dihydropteroate synthetase-like
[ 467] ------112112121--------1111211214121111111111131112121111--1------11 3333433233332354555-555566666665555576B93444325221122222221144524333444111111112222222321111121111-212245212211111111111111223221122-22444331113244422232233222223322255331121321111122222323124244444434253444323333335233323222223222222222222222222222222222322322222222222222222222222222222222232222222222222222222222333222212223222222222222221322222122114132332222223321-1121-111211111222223121112122222222222-11111111222132252342323211111211111112111111111-11-13111111111111111111-111-1111111111122111111-1111-111111131111111221111112111221111131112213111221111111221411-21132232242212212221211332324221111111111112112111112111333322223222223222334222222342321-11111------42232323343333333-333333333333333333333333223333333333333333333333333212222222222221111122111222124122222221111-122232323222221222224223243332223122122222244432222222333111111111111111-323332111111111111--1--2---1-21-----11-1----22222221321211 22221-1-2-3342566878787656744353445634442345449457586935655653244453255663455255566565423486635465345158C913C42555355453143455453BU613381322325454344234374553714242421833255424763K34376C7AA3A43445531 --------------------------------------11-------------------------------------------------------------------------------------------------------------------------1------------- * c.143.1 CofD-like
[ 468] ----11-------------1--------1--------1------2----22--1--1----------- -12---------------------1------------1-------1--------11-----1----1------------------1----------------2121-1--------------------------1111-------1-41-1-11--1-1-1-1---21-1-----------------------11111-111111-11-2----12-------------------------------------1-1--1--1---------------------------------------------------11---111--2--1-----------1----11--------1-----------------1------------1---------1-------------------1------2----1------------1--1---------------------------------------1------------12--------------111111--1111---1--112-----1---1-1--11--21-------------11-11------1-1------2---1-1-1----21-----1----------1------1-----11------------------------1------1------------------------------------------------------------------------------------------------------------------1-------11--------11--1----11-------------------------222211--------------1111---1-------11---------------------------------------------1- 3245BAA-F77576787B697A7979787798899868A78667667A86F87CA8A79777663648165565787479576546878AJ57E9KA7A5575CCC2ADEUJUKQJNCDCFFGEXPDZA**Q4YSQBEFAQFGJDAGE8ARCAaAKFFHBPdCIFG9KAEDKJKB6764k56546Wnow7cJ987A566 -----------------------------------------------------------1--------------------------------------------------------1-----------------------------1---------------------------- * a.118.17 Cullin repeat-like
[ 469] 22324311111111113332122666674764333775666665576755667554444541123122 222--116331-1-11111-11--11111112111111111111----------------11--1-1---------1-4443434444223213232--22222432221111111111111122223232223222233111224554444433311121233435543-111---1-11-3334333133444444464444644543554644445454444444445444444444444444444544444455454445555554544444445454444444444443444444444444444444454444444435466666666666654665666666463657544343535334563455245111111111111111112111111111111111-11212111211211111121111111111222222223211111111111112111111111111111111111211112111121111111111222222112223323222222222212111111212111222111112111121111111112112156665555665554556556566223221345222222222223433223343235112211413122412222232222222232331-11112------21112111111111111-11111111111111111111111111121111111111111111111111111111111111111--11122112212112111111111111-1111111111111111111112211111111211111111111233344444233331111111111111111322211113333333233333322-331332233321123411133344535551442 2---221-4123-1414341--11111222312-1-11-113321132143222331-244521111111113211131211111132248242231211363221139362222344441131A1261GS3-538332-43443123233338423342451232232431242-1-593321-41-53225523213 ------------------------------------1-----------------------------------------------------------------------------------------1-------------------------------------------1---- * c.107.1 DHH phosphoesterases
[ 470] 321112123223234311121111633442631111111111111-1111321122243431111133 -114322322322233222-222235222222433334644554222322234333332233433333432222222211117133452222123321133334445341111111111111112212222212245554222232443442332222222222236454222222232222333341224234444444434444443433334433554332333333311333333322333333333313--111213333221111-12111111111112222222222222211111111111112222222221----2-----------111---------5---1--221-2---222-2--512233433333454786446444444444444444-3252253343353333445333555633364443444543333333344433344221222221111111111111111122222324331222221111223334222223333312233721122252122213223112123111--1111122243422-112111122221222222242332342324444333333333333333343466442122331211322222222222222222231-1332211111111211112111211122-1222111212111112112343211111111111111111111211111111111111111111111121111111112232322222211111211122222111115222223322233333222111111111-11111111111111222222222222221121222222--------1-1-----------1------1------11111111112424 44-2332-C452222222222222213222222222233333322222222212223222222332222322333221222333332222222222222322222312A26385574424333563223EG7-43632243433134133333455325535434E3534122437645*687679DGI2B96765444 -----------------------1------------------------------------------------------------------------------------------------------------------------------------------------------- * d.52.8 Fe-S cluster assembly (FSCA) domain-like
[ 471] 11----1-----------------1--2--1-------------------11-1----------1--- 4MU-6---------------------------------2------3--1-1-952-----541-4--JB82-------------------13-1--1--13-4787N-4-----------------A21----4-22222---9-622-1131122----1--7-Q319J-----------------------11111--1-1-1---2222-2-1--------------25--------------------------------------------------------1--111-1-1------------------------1--4-----------21111---112--1------221--------------L1------------2----------------------2--2-----------------2---111------121--------------1--------------------------1--------1------------1111---1262121---1-1-----------2----2---2--------------1---68251--111-1111111-4141-1--28M15--------------------------------72-3----1214-1--311-11133---5---------------------------------------------------23--1-------------------------22222222222--11---------2-5----------------------------7----1-1-------1-1-------------------1--2-1---1-----------3-11--67-------------------------------------1-121---1-X-- --1195*-----221--2-622-2-21-------2-----------1-14478433-3----1----11-------1--11--------111-1111111111332-7A2aYWYdWbMOLPNPQxhQhP**X-iSxHMPLaNPURFRMNGdNExMLGPWIQKEEA86E69M33A4-122C1-12121-2-11231---8 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.69.8 Integrin alpha N-terminal domain
[ 472] 2254543555455366545352285441142242446531254584858497BA57716162336211 5CG33-1-----1-21155-52227155555522221-211333-1-1-111111-----22--241242-1---1--1337-222113334-54311-3452233411--------11-----677558376463446665432-225333122221-1-11333231--1-----11---22333652311111111211112111121111111C8221-1------11-------------------------------------------1-----1-11--1-1111-----------------------------1513544444444438444332232443-322576113126121113234322111211111235432114558711221212212-5656825316414112232523234232332432332224444444434442A4411-1111122-11111111111111----142452111124333242333333343333134533326224343353324433242A53324411111112215562P9D647546534549GCCH9F8E4454AF7I2233122223113111111122115335551122423234554456444444554551-11333--1---54344523554343433-53333333335443333353334322345454444444444545447332421434344434444111211111111142434111131121121221223422322233223234332222233333111111112433433333346652332322334122211362233331111111122--------------------------6526676867-314 2311-13-5123-1-----1---1-1-----------112----------11--1---------1-111-11111------------------------2-11-1---8134221122423--3-22256C1-224312-33---2-321--221323--2-124-1-1111-311312A1-1341--5-19--21214 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.125.1 Prokaryotic lipoproteins and lipoprotein localization factors
[ 473] ----------------------------1----------------1---------------------- ---------------------4----------4-------------------------------1--------------------------------------22---------------------3--------122-----5-222-117-------6---5--234T-----1-----------------------------------------------------------------------------------------------------------------------------------------------------------------5----111---------------1-------------5---1-------1--------------------------------------1-------1-------4-55-----------------1--------------------------------------------------------------------------1-1---12-----------------------1-2-----------1-------2-4--------3--------------------1----1111----1----1----1-----53--1--3--1------------------------------------------------------------------------------------------------1--------------------------------------7------1-----11---------------------------------------------1-----11-------------------------------------------------- --1---C-----11---------------------------------------------------------------------------------------------R2-ycpvq*fQQOLYaU*yJ*F**x9*b*SKKRYUTWMORKKMaUG*TidaqGf*COdC4DA6Q7H*6-2----------------123-21 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.1.27 CalX-like
[ 474] ---11-----------1-----------111-111---1-1---2-1-4--------------1---- HLg----------------------------------1-----------1--2-1--1--1-1-6--1211-------2312------2254-321---1811193632----------------11---11-3--1128---7-----1--2----1-----------1-----------1422-1------------------------------------11111118-1114341--111111-2111-----------------1-----1-----11111----------------------1---6-----------------------1-----1------11----332--1---------1-7-31--1---------------------------------------------1------------21---1--------------------1------------------------------1-22-2----111-111222222-1222213--112------1---22-1--11-1----------------1-1-13-3-------------1-113--11-2DC-----------------------------------11--11-----1-1------4------2-------------------------------------------------11----------------------1-------11111-11111-------------1-1--------------------------1-1---------11---1-----------------------2111111-12311------------11------------------------------------------1------3 1---A92-1-1------11-11-1-11-------------------------11-------------------------1---------------1111-----------5FaBOqKNPACJQImgMxM**m-*igIDJQgNQse9IbGNfPAVQYLLh24211212321D1-11------11-----2153-41---1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.3.5 Cna protein B-type domain
[ 475] ------21222222221211111-------------------1--11--1111--------222--11 3421432222221131111-12112211111222223233-22211142221343233113352332B6611111111----------11-1-1--1--1942262444------------------1-1----112211-----111-441-1111111111112111111-1111111-1-11---1-----------------------------------------2--------------------11111111111111111111111111111111111111111111111111111111111111--111---1-11-1------------11----1-------1---------------1--1-142211111111-----------11111111111-11111111211-1111111111111112-1112121111--------11111-2-------------------------------122121111122222222222222122222222111111122211111111121111111-1111111112111111-1-1----------111--1-1-331365-2--------------------1----11111212333313444443344443445434--11111------11111111111111111-1111111111111111111111111111111111111111111111111111-111111111111--141111122221111111111111111111122222311111111111111111111111111111-111-1111111111111113444433311111-2-221111-------------------------------------1-----------5 1111673-744-66465444644444544445433325553544544445466644454444575554456575755256544444333593536443335435664646QHHGLJICBCBABAEDBIAY*J1JFRAC9BDBDJEBDCC9HCBKAFCBBBOXMQCNKfMXnIOGM3454P53264858C45C348DB83 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.98.1 Leukotriene A4 hydrolase N-terminal domain
[ 476] 22-12----------21-11111-7332515212-------1-------1363-112-2--1121-11 2232421333322323333-33116333333432222444243432431111124313--334233627221111111---2511111112413-----2313332322----------1-1111111221112123232---2325214321211111212222232521111111112112222211-353444444444454455434423455453412121111136222232222222222232232211322-122221122111-1-222112----13322222332222-------------111111111-33212222222222331541--11131232212214314212242221143122222-----232344242422222222221224145324424341-444322542334322223423334333222222223334212211111111----1111-1111-11-11111232212222243244332222442332222454322341143223232332222232111122122222212322119842242124223-33323432211113232222212222212312222122311212211231412232222232222233222332122222111111122242222222222322-22222222232222222222222223322222222222222222221111221233333333333111222222212242223222-11-1111211233333333223122223232233432223111111111222342434323222333333333311111111111133----------1-------------------------2-211111112422 21-2424-A2142225344644555555544444446445554333544456A85533334433433322324444333333333343334334334443363556-4A5D346336634343486354Fj4172A2434524642442344253343522745453B42234733464J84354A52A4945385426 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.1.23 FAD-linked oxidoreductase
[ 477] 111-221111111111------------1---1-111------1---412666---------1---11 -29-----------2------1--22-----21121--1--1-2-------------1---------121-----------1-1-5-13312----3------151-11--1111--------61-1-2-1-35-25454---9-7-7112921----1---1-33-27H-3-2-115-211-11-----11---1-1-111-11--1-----1--1-11-11-------11---------------------------1--------------------------------------------------------------1--21-----11-1-----1---2-2-12-1--11-1---------1-3121----1-1---1-121-------1--------------2--21--1-----1-----2---1------1111--------------1-3-2----------1111--1222-1111-1-1---11-1-----------1111--35------211--------11----1------1--11---1--------1--13927-13--1----1331--1514-1-11C22------1-------2--1-----1-11--1--1----2-----11--------------213---------------1--21----1---1------------1-----------1--1----11--1-1---------------------------11111---------312-----------1-------1--------2-----1---1---1111-111-------------11----------1111-115-11122--------411-------------------------21-1--1-1-122- 3413CE6-A21173B5453D673686545643344585243555344436838757656444232343315433244244432214342334483X66543B3AD7-457*QQMPMKICGGGRKbX9U9**O4ROeGEGDXFOSGEKHDARFDXFQIIKCTFBHD94IEEG6BHZ4141O43274D45F5A76754659 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.7.14 MIT domain
[ 478] ----1--1111111-1--------1--1--42-1----1-----1-----1-1--------------- ---11--1-----121111-1311311111122141-3131122-111---1221--1----1-2-113121111111------1-11----11---11-112111111--------------31-1--------1--1----1----3---1-----------3-2111---------------11--1------------------11---------1-----------11---1----1----11111-112-111-14122-----1-21-211-------1----------------------------------------11111111-11-1331-------1-12----------------1--------------23-11----2--12222222122-------3----------1----2-11-----1---------------------------------------------------------1--111-2112121122122322222-2122----1-221-11----11-------2---1111122---11-------1122---1------1-2--1--1---1----1111111-2112222---1123------1--12-----------1----1-1-------------------1-----------------------------------------------------------------11111111111---1-----2222113-----------------11--1----1--2222-2311-111--------------1----------1----------------111-2211------------22-1-----11-------21---1111---1--------1 331245M-SC735455483445735464444343344444424644455484563654355665565426455654445456666634549745356655446C8E18D7VXjXVMRJGHHHNLmoGZF**U7eMuEJHDWGHJHBKJHDPECXJJHIK6B9KOIF8S99T78G42423Y33255944A443557BBD9 ---1-1-------------1---11----------111-1--------------------------------------------------------------------------------------------------------------------------------------- * b.34.10 Cap-Gly domain
[ 479] -------1--1----1----1-------------1---------------22--1--1-1-1-1---- 2223333333343323322-22333222222323335343244332232333333223224422222112211112112222222422222222--21122222222221111111111111124322222422332222222226323222223322222242223333222222222222-----22212222222222222222222222222222222323333332222222222222222222222122222222222222222222222222222333222222222222222222222222222222222222223222222222222223222222212--244222222232232--22222223222222222322232222222222222222322-2222222222222222222222222222232232322223333333322242242222222222222222222222222223322222222222222232223233224433332322432333334322222332422333222223222222223522222432353224222232332335532433242322222222222222222222223222222222224222222224222222222222212222222-22222222322332222122-3222222223322222222223222222222222222222222222222222222222222222222222222223333232322222222222222222222222223222222322222222222222222222222242222242422223333333422222222222222----------2----2-343323233323224333322222222223222 2212123-823-22333334333333433333333333223225334434322133353333332422132122233233333334333343334333323628BA125-74844323132343422528i614623312512552341233384422438532239424745534332M33412378A3664332223 ----------------1--------------------------------------------------------------------------------------------------------------------------------1----------------------------- * a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
[ 480] ------1----------------1-----1--1-111111111-2-11111111-------------- -213F3132231--35422-251158222224855566B8341-132--222834--3--6532656DLB5-------5---5-----122---------1---2-111-----------------------------1----1-1111221111111111111111211112111111111432-----1365555566625555657666575553453547899A98112333333333333322112296425B22948AA22965395342322224333322444444444444444444444444356221555422-38222222232536--2444-111-2----78121-5--212111-3-1-533211111113451-11313155555554558-116-1714361-A7765668779A321312553125456--------2332--21-------------------------------222-6FE9A9999995877888BB788856B9EFGF922776232124447754322222631111111111222-42---13--1--2---1--1111----1---1---1--------------------22542231226352222122222222222222----111------65742637776755588-7778743878756667665797562217467676777677777565456664-444354444455--121111111111155611112------1111555552114312887866894755514571111111112333233333344332233333333----111122-------------------1---1---------1-1-----23---612-1--- --111---11-1---1----11----1------1---------------2-1-1--1-1---------------2------11---1----1-112-----1-------2-111111----2------------------1---------------1-----11-21---A-----222J22214-1-2-12--21111 -----------------11----------1------------------------------------------------------------------------------------------------------------------------------------------------- * d.190.1 Chorismate lyase-like
[ 481] ------------------------222---2-22---------2-32--2-----------222---- ---2--2244422242222-2-22222222222222222212-22222----324212112222-221-212444113332----11322-224-----2323145143--------------------2--2421443233524-222--22222---2---31----4----211---214-2212-2-11-----11-3-1-111111111---1--1-423332322211111111111111111113-222--22---22-----2-2222--111-----11-----------11-121-22221-1--------1122-222222222222-2221----1422-4-22221-2--2-33322-141-4553-------2241-232--22222222222-21311323-22335--33343312222-41--2-----2---------222-2-45--2222221----------------22-22125621111-2222221----11-3------22-3425--2221-13323121-2213---21-------33121--34341-213111113335475441242344444332222224434224224----233--11-1111-111111111111111111111-12-21-1-222-------1111111111-111111111111111111-111---------------------311111112-1--------------1222221111-1221222-222----222222222222-32------------------2444424443111122222-------111131111111-1-122----21122222---22122--2--25--2-1-211----2-222232123--2 532-524-M8B466535654754666633457744443232223225321243433A2544668A9BB5ABAB8B9A798A778976648I85B6CB8456459BD-4I6A4AE9898698A85BB48AF*6-75A9C38A9575777777677355835CD36551F4A387514978*647568FHj3OE384434E --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--2- * b.4.1 HSP40/DnaJ peptide-binding domain
[ 482] ------------------------322122213111-122--2121112312211-11111111--12 2221222333323223422-23222222222242323253223221131112211112123222232222212221112113212222-12--11111-11--111111122222221111111-1111111111211132222213211111111-----111111111---1-1---11111-121-1122111112212121222222222112222222322222222222222222222222222222221222221222222222211-22222211111221111111111132121311111222111111112122213333233232122222222222222121112322212322211-1252111111111111111111111111111111111111112121111111111111211111111111111121111111111111112111111111111111111111111111111111111111111111122211111122211122111112211111322122123111311111222222222111322122211222211122121322332222234431312222221111111111121341223111111131111111112111111111111-1121111111124321113344343533-53333243354433333333232123242222323323333221344321411333333333333111122222333331111111111111-12111111111111111111111111111111111111111111111111111111211111111111111111121111111111111121221111-11-1121-1---11-11111111111111121- 2212554-H982433436345444434554555657344544575549343323343543323332342543434542433433332235723527623538464C1463I8B7B855854497CB4A4Mq8194E6256E379556543E54C6B58g2A35969EE45456449434Z44363aBMK5F82156685 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1- * g.54.1 DnaJ/Hsp40 cysteine-rich domain
[ 483] 11624433222222123254434553322365-1211-322223523223624-36134572444133 5243421122211233366-6311436656633333425464532122----232212--536133354651111222--123-443411111-11-1--21113222122222221111111-1111131113132243---1533335534433231334333433432221222221222224421-22245555545255554522222254433211112222213212222222112221223323----11-11--11-1----1-1-------1-----------------1111111111111---------154-111111121-1-12242111--311522232313712753111551-232222321111222223322232222222222222-22223622222-22221121123223232212222222322222222222115121111111111-------------------32221233333666556333336644444446644555622234553333445335576454332222323425566-2332543233233-4451326935445542333222222222-2111111-25222223344334232333334333333534333332-1254411-11143332333455364533-B4374735568664433443433333333333434333353333443435511322343333243---3221223312335344332222333422233233323333634444444432232433432333333233332323333333333333323332222342-11--------------1-1-----------------1-----1211--1---411- 1111343-3112423222111-31132221222221-22231222223323212222122221111111111-21111111222211112222233111111311113511312213111221141232352-1131111111222311-11-221123319132122232-3-2423292313276362441121131 -------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------- * d.15.3 MoaD/ThiS
[ 484] -------------------------------------------------------------------- -468722322222256655-5E44565555549689547713341-21---11121-1--3233336C97111111332132-112233322-3-----1823-73324--------------1221335222-522222---122233221--11343755-2213343-2-----2-----------13123343434434444442211234442221---------32--------------------14222232321442222223--1---111-1-1-------------------------------------24157443444454523332221-3312123121145324-21---1-22121411422222ADKGECABDEFED8899789898C-JNIKPGHHEI12CDDAIGHGGHGEAB-21D3A8888665111111112--11111-----11-----------------------55511-----1111112111111111111-11111111----12111123112-2141222262222222342232F2211121121111-66626372544-42D773111-1111111111111111112D556631632---334444334555334443441-33432------65444536666666666-66666666666676666676664432376667676677575684656666511323233333333-112AAAA9BBCC91531111111-1111111122222222445255553444426235222---------2111533333443333323233222------31--------------------------------------------111111114191 ----1------1--------1----------------------------------------------------------------------------1-----------1-----------------1-----------------------------1-----1---1-----------------2---------1--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.160.1 L,D-transpeptidase catalytic domain-like
[ 485] 22----2-111111211-21----11111111--1-------------------13-1---------- ------------------------------------------------------------------------------------------------------------1----------------------------------1-1111121221111111111132112111111111111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1-222222222222332222222222222222222-2222222232222222211-2222332222322222222222222221222122222222222221122222222222222222122222222222222222222222222122222222222222222222222222222222222222222222222222-------------------1-------12---------------------------222222222222222222222222222222221-1221222222222222222222222221-222222222222222222222222222222222222212222222222212212222222222221122212112222222222222222122222222222222222222222222222222122222222222222222222222222222223222222222221-222222-------------------------------------------------- 2211443-622-2343353322222333332223342544445122443445543385433433333321334333424433344543329533453434233365-2C4k9GIDDAJDILNFFmVEWL**R8URiJJHFEHNKFCGNFBVCCk86ABL4-17B98E8EP85573455393224354682744334234 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.52.6 BolA-like
[ 486] 22212722555556655154324512241111322241--11-3334232255532221412333111 46712111111-1-1-122-22--1122222-122211221451111-11-1121-11--1331312143-222222243562312-16567-533---22121213-2--------------173352414354111343221-4378336233332421244465587-21----22-1-1-1--2141233333344343535351355223333223134222222344444444444444443442221-12211111331122221-11222333333434433333333333333333333333333333333333546C4346556978656655647431426552756181342411-3225-262333-----234343235664521222222222-66467368352143333323442343-12-2413111123333333312222515------------1111111111111-----342422111322222323333223533333322322321112313322323511333252432-------1126451I6511342512332474679644455469252111------221-------22-2211445312322144544455532334355364--113231-----43343434445444444-4444445444454444444444234534344444444444444344344342-333333333322--112122211112222333322223323211223333332331334245435344444233---------14455444442344431434334441111114-111111--------3-2------------------1------54343645562633 1--------------111-1112111-11-1--1111222122-1---111111111-1111------------------------------1---------------2---1----1--------1---1---------------------------1--1-21-----1----1244I3332--14-111-3---11 ---1---------------3----------------11-1---------------------------------------------------------------------------------1------------------------------------------------1---- * d.350.1 YcgL-like
[ 487] ----------------1--------11----11-----1111121141------1111111------- 1111111111111121111-11111111111112221111111111111111111111111111111111111111111111111111111211111--11111111111111111111111111111111111111111111112232553322222222233123334222222222222-----11122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222232222222222222222222222222222222222112222122222222222222-21--1111111111111111111111111111111111-11111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111211111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111-11111111111--111112111211112-112111111111122222122211111--111111111111111111111111111111111111111111111111111111111111111111111--1111111111111111111111111111111111111111111111111111111111111111111111111111111111111311111-111111111111111111122212222221121 11-1841-B592EH797C75999BAA7888888989776777788896787B7776A768774553333644354432343667966565EB7EFC75795C4766-36AB757B594455456784D4Df9295F44557357265543965D47555288565t6777C676F2841923266GJIJ9JK3146782 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------21--- * a.149.1 RNase III domain-like
[ 488] ---1---11---------------1--1---1------------------14---------------- --2-7---111----11--------------F---------C69----------------31---215874-----1----1------12-1----4------------12222222111111-31---1--8114111----6-4-2-333----1-------151319---------------------------------------111------------11111221----------------11------11-1---------------------------------------------------------------1--1---------------------------------1---1---1------1----------111111-1---------------------------------------1-----1-------2-------------3---------------------------1-1----2-------111111-----63-2------1-1-11-----11--------1---2---------------3----52--1-1---111----1---------12--------------------------------1-1---------------------------1-------------1----------------1----------------------------------------------------------------------------1------------------------------------------------------------------------1-1-----------3-------1------------------------------------------------- 11--31A-53-11112163H575EAIA5443227453434443221794PD7AJ233J22123--11---11212------2212-3-2215121*11-1--2121-1q2zKMRNLBHKGFLKHugJjM**c5kUkEGHGSLMZP8MGABREBQJIEJJ79CFJB62867934Gz-AK2P422136896D515134219 --------------------------------------1---------------------------------------------------------------1------------------------------------------------------------------------ * f.1.4 Bcl-2 inhibitors of programmed cell death
[ 489] ------1----------------1---21--1--1---111111---3-----3------------1- 11213--22221-1-11----111-------------1--223341--2----231----221-4121431----1------3----------------11-111-1-1---------------1----------32246---42642133211--------22115532------------425-1----2222222222222222223222222213243131111115212222221222222111111321--------11--11---12-----------1------1-------------------1---------25214222222212125112211224-442-1111234-2311-112-11-122112-------2221112132111111111111-32222221111-11-11111111111-2-2432222212-----------1-1----------------------------------21------1----------11---------1--2----21-22--------------------11111---2--1--------------121-11--21111461---1-1-----------------1-1-------11---1-----1----------------2-----------11------------------------------------11-------------------1------------------------------1111--4-----------------111111----1111111221111121222-------------1------1-------------1------522----111111111-------------------------------------11-1 1-55EC4-1---CB345353332432133-111-2-13233332325533545654612333235343162252223132255533---24153481123-725121156*GJCCILDBD9GCCQJDMBg*H-LFZBEEBJBCFDCEECBF99JBECLKfYDPNKR9aLb9Lj*81EY2----E1BQGP2ME1IXRTb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.111.1 PR-1-like
[ 490] ------1122222222-----------1---1-----------------1-----------122--11 12211-1-221------12-1----111111--------------11--11-121-------1-11-12---1111-1--11-1-2211111-111-1111111-2131111111111111111222211-12111---------212244-11--11--21-11243611-11----111--111111111-1111111-1-1-111122211--21111-111111112-----------------11---1-1111111-1---11-1-------1111----11-----------1111111111111111222---1-------------------------1--1--11111-1-1-11--1--11122311117515214542111213111111111111-21111111111-11111111121141111112232221111111111122211121111111121--1111111111111111111322223333444454355543353555635642243513334212222212423323322421111111223123352122211122221121133321333343221211122222222222222253121112311122221223222323222322353321-122111--11132332332222222222-232232222222312211223233342333323322333333342333222112222222222221121111-1222211332111111111111111112111121142777744243243241321111111112222322222332222122112222111111311122221111111122----------------------------11--1-1-2211 ----561-334133242212322333233322232223443552323523333222233432332253333252423-22422121221262224222223122623424LECCECD9878999DE8G7R*E1GCS8B69E99978B967E89G6787A7KVHL9QDYLah9EBJ13-2J-112354662142223351 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.250.1 IpaD-like
[ 491] -------------------------------------------------------------------- 1-1-2111111---3------2--24-----132221334-1111-2-----1311------2-2-2122--111-------2---------------------1-------------------11---------1---------------------------------1------------111--11-------------1----132--11-------2--1-----21----------------------1--------------------------------------------------------------------4-------------1-------1----1----33-------------1----111--------W67--57387511111111115-22222222B1--14433396336653---46741453241111111111111-1-----------1------------------1-----Q****12232121111221111111121D****9G433I8sji*e*4**4A1-----------------22----2-1------1----------1111-1-----------1------------------1-1--111----------------------------------1112--1-----1-1-------11--1--1-11-112111--31-11111111111111112-----------------------------------1285----11--------11112111-2-3111111222312122222-------------1------11-1-121111111------------11------------------------------------------2------- ----11----1-12-2112132312-12111112111-1--1111122111212112--211111-21-1-1111-----111111---12111111211111111-11-7211112-11-1--21-23383123311111-111-21--1--11---L----1-31-26---3--11-5---11421l3132112-11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.288.1 UraD-Like
[ 492] 11-----------------------------------------11--1-1------------11---- 2362622222222253333-342234333333344445CB2733332231113633321154226498752222222222223333334323-3223--232225232222222222222222222222222222333342224344344442233333333333654563333333333333332233112133333333233333311111133422211222222221122222212222222222222212112111112211222221112221111111122111111111111111111111111211111111121133222222223212332222222321222222212211111112211332222422222233442223222222222222223-24224332232233332332322232222234323322222222222322222222222222222--11111111111112122-2223233324734445557776566888837734555322323323223222422222322322222222222233323222232242222212122131335355222112122222222222222222222223332332222322222232222222222331-22222------24233232433244443-3123223325343222223433336533433432333333332422222232-3777777477761122222222222224331111111111111113333333222425555344355335343311111111124343333333443322324224452222222233333311121-1-33--------------------------22234322332222 34--211-711111211221121111211-11111111111111112111111121121111121111111111111-1111-1111111311111111112113211412--12-11-1---------4C5-2----1-1-1--1----11-12-11132-1---------2--2484k33344DCAO1IB3442213 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.174.1 Double Clp-N motif
[ 493] 2222222222222222212121122222222222221121122221-111111222122213222122 2111622333332223466-643344666663444443231425222132311112112253423344222222211111131-----211121221--2112112111111111111111111-12111111212113322251-11------------------11--------------22222111234444444344444443444444444335442233433322344444434444444333332131331211133223322322222233323333222222232222222222222222223222222222122411111111111121112221131231223333221222222221-1122222232222111212112122222222222223-22223322221222222222222223212223222222322222222111111222212211111111211111111111223122121133334544444444444444444444444444411444242222212222232323332222222222232223212121222222111111121111111221111111111111221211211111-11121221112111111111211111111112-23222------11211111111111111-1111111111111111111111111121111111111111111111111111-1111111111112212333332222222221111-212221111133333332222222222222222222222222222222111112222222222222222222322221111111111111111211121---1------------------------------2212 56332332E4343333432243323244433333333444444344433433333444432342445532442335546552212333344343432224343414438385749471135333764B1FS4-A494445724432332232442655755246382466-36332342L2243347B63853323423 ------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------1-1-- * d.74.3 RBP11-like subunits of RNA polymerase
[ 494] ---------------1-1----------1---1--1-1---11--1----111-----1------1-- ------------------------------------1--1---------------------1-----------------------------1-----------------------------------------------------1-----1-----------1--111--------1---------------------2------1-1-------1-1---1--------11---------------1--------------------------2-1-1------------------------------------1-----------------1----11---11------2--1--------------1-------1-------1-1------1----------------------11------1-11-2-1-----1----11--11111111----------1--------11----1-11-11----------------1--1-11----11-11-----2-----------1-11-11---1---1-1----------1---1--1--------1----1---2--------1--------------2---------1---------31---------1------------------------111-1-1------------------------------------1-1-------------1-----------------------------------1-11-11------1-------1----11-1----2--1--1----1----1-1---------------------------------------------------------1--------------111-11---11---1---1------- C956A98-U77665865559675D8C75464566676767698555559878B857986756555545246444646266556476565685558975544A666746B9aNdXROYIFIFFFHbTEgEy*W3bQrEKECX9HMFBMGEDUCEiHOHLHCA99ABQBC9CDBFA9C686X54457DBDE7FB5779BA4 ---------------------1-------------------------------------------------------------1----------------------------------------------------------------------------------------1-- * e.25.1 Sec1/munc18-like (SM) proteins
[ 495] 1---11------------1-----------1-------------1-12-2351---1--1------3- 5Fa19------11-1---------1------13----212121112---1213111-1--141-63441231111111--112-----668A-E33---443359-4A4-111111111----2---------3-55564---B5251-44422----11--42-312-1-1----------322-------111111112-2212121-11-112112--1--------52----------------------1-11---------11-------------------------------------------------------1---------2-1-1-----------4--111-113-----122----G-83448--111--1111-------1111111-111-1111211-111-1221-11--1-111345--1--1-11-111111111223--4---1-----------11--------------22331-----------1--------------1---1----11-21---1---------------------12----31-1111--11----1-1---2--7636E5-1---------1-1------------1-----3--2365-566446466655657656A----1-1------1211----112-1-1---1---------1-----1-11112311--1--------------22--111---2---211-1-22---51111-1111------1---------------------1--211112---1----1-----------------111111----7589A978892222--11--------------11--------------------------111-1-1----7-2 --11113-814-7664657475357443433433333343323563724288A764744545224523336232222-2232223442258463543132424646-4749QTIJIC99689D7NI8Q7z*Q5aNgA8A7M8DG97F887D77M7JEAC7IM7767DWAAhA9883536V32143GBF87B34375342 -------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.70.3 DPP6 N-terminal domain-like
[ 496] ------1-----------1-----22222222-----------1111211111------11---1--- 312---------------------------------------1--------1------------11---------------111-1213322122231122122723221111111121111111121111-111211121113253222232222222222322323222223222223321121111112222222122322122222112222222222231111112211129211211112111111221122111121111221221212222223111122-11111111111211111211122111332111222432554555635462332322333132321122321334122322111113111111111111111111111111111111112-111111111121111111112111111112121111112111111113112111111111111111111111111111111111-11111111112221221111111111111112211111-1111112-11111111111211111111111222111111211122111111222222211111221111-------------------1-11-111111111111111111111111111111111-2211111-11111111111111111111-1111211111111111111111111111111111111111111111111111-111111111111--11111111111211111111111111-111111111111211111111111-1111111211111111111222111111111111111111111111--1111111111111211212-------1-----------------13121111111111 43226771E564655678747766659776676767877776686758766686678765664534743766544763776887774546A677695567776C752885HA8687765655769A3E4**B1F8C55679577375668856A697456CE57564664736876366T55446946A77I3567653 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * a.113.1 DNA repair protein MutS, domain III
[ 497] 11----3222232222-46542244--24646-112211-1--34132144442-1----------42 223-432444423256755-57--86545554777746864563122-4---345222--437-4454464-----------22-4-2----2-------5-22343-2--------------1232222232-2-11-----4-433333433553333334333535324242224242233222---21333333323333333332333333342111--------2211111111111111122221----------------------------------------------------------------------12-392222222627-4223453221---11-355843--1371112--3-244333-----565562224224444444444444244444544352-6663554554445633234422224335555555512223522------------------------------24332222248468884999966889999768684664-3457433334333433335453221342222112343-2334333433333-424-44461214224133-------------------32-44115164433-32322222342222222432332--1522---2224444-443333333333-3314333333333233333464462234444444444444444533333332-3333333-333322-1-------1-343552222-2------1--33333242343366666674557655546---------253342222235455--123221111111332-221111----------------------------------------------232- 1--1111-11-122222233222222211211211111111111113233222232542333113131211-1112111111111211135222131211233311--912------------121-1-28-1-13111----1--1-1-2-121---2-1--2-2---3-1-5-2434U3334395872345632224 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.36 Nitrite/Sulfite reductase N-terminal domain-like
[ 498] -----------------113122122221122-----------1111111222----------1---- 433---------------------------------------------------------111-------------------121221443313223--332338362211111111112222134333332343222221112322222222222222222222322222222222222222212222122233333233333333333222233312133232222223333333333333333322222322133123322222332222112222222---3221222222222222111211111113222222222244524434434243544433347221222-2355433322342332131242111111111111111111111111111111111-111111111111111111111111111111111111111111111111--11211112111111--111111111111111111-111111111-1111111111111111111111111111--111111-1111111111A21111-------112111222223333343332222222213343335122--1-------11111111111221331111211212111111111111111111111---22612-11111111111111111111-1111111111111111111111111111111111111111111111111111-1111111111111112-----11112-1121111111111111112222222222212222121211212222222222222211111111111111111111111111111332122222222222212211-------------------------22222122211112 3322654-C55245566464555554666565656565554556556655555645666566443453-564334653555445653336D566766565746665289484655474444553672C3*s8-8395544635634542564574754526E3437323263575767Ay77658A56858C5655555 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.203.1 DsrC, the gamma subunit of dissimilatory sulfite reductase
[ 499] 33333333333333334344343333333333333333333333333333333333233333333322 1111111111111118111-12111311111148251232111111131111111111111111111221111111111111111111111111111--111122111111111111111111112111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111-1111111111111111111111-11121111121111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111111111211112211111111321111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111-1111111111132111112222222122-22221222112222222222221111111111111112111121221222211222222221222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112112111111111111111-111111111111111111111111111111111 44335443D7734444333544436334444444444534444444444444444454333332333313322333533333441167748333435464433A9G4454877444542F8473aQ3Z5e*J-CGu2257d43M423469723G374455454446384B457535544b44334GBFO3973455553 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.12.1 Ribosomal proteins S24e, L23 and L15e
[ 500] ------------------------------2------------------------------111---- 343-2---------11111-11111111111111111111111151-211111211111112112-122211111111----123444EEH93C68---222222212111111111111111-2232322243211111---21731122122221111111113214111111111111142111111311333333333344344221112334111111111111112-1111111111111111111111211211111111111211112321111111111111111111111-111111111111111111111211111111111111211111111-1111111111113211111112122132644333333536344443433633333333334-2252453443426557333444333334334335333346666666658645A43123333331111333313333333333333346433433343353353333336932333334656783386543465335353336464454333433333343845445357464786254597554C4434445411-1111111111111111112111865652455335455555554555445444441-3534431233344444544444454344-44445544454544444456444444444444444444454444444444451544444444444--8445555333344443333333333333333333333333375555554565555545551111111113644444444445444444544444444433G-11----111111111117DF13--13112-11111--1111112111111112232 1-------1-----------------------------------------11-1---------------------------------------------1--------1-------1-----1-13-1-121-121----1--11-----1--2-1-1-----1------2----121--1111----1---1-1---- ---------------------------1--------------------------------------------------------------------------------------------------1------------------------------------------------ * a.55.1 IHF-like DNA-binding proteins
[ 501] 11111111111111111221121111112111111222111111112111112122122222111111 2223222222222222222-22222222222222222222222222222222222222222222222232222222222222222222332222222222222222222222222222222223222222222222222222222222222222222222222232222222222222222222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222221222222222222222222222222222222222222222222222222222-322222222221122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222212222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222224222222222222222222-222222222222222222222222222222222 11111111522123333332333332233233333333332333331333333333333311333344234234344444433333444353344333333534551251213112112C32318C14-3C3-125-126211213122-12-1221111151312-224311124353p3333588EG3651111112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.141.1 Ribosomal protein L6
[ 502] 22-1121111111111-1--2--1-11-----1--11------1-2211212111-11111111---- 32322111----4----11-11--2111111-2111-1111-1-----1--1-----------2----12-2222333112--222--222212-1---14221512-2---------------11111111111211-----1-233522211332212221421325-121111131111111111-11--111111----111---1----1-1------1-1111--2-11111111111111111-12211231221411442121133122234333332221111111111133333333333331332333333-2-11-------2-2-211134311111-31-----1--11-1---1111--2111------23122--22--1122222221223-43334533131-422321-143--221-1111----1112222222244432--1-------------------------------23-21-1125555555544355645555248542313-1544212--21-12111-----232221222---1113242131211311111-1-11-22222242-11----11111------------3323322-111112111211211211121112111--112--------321-2312222222222-2222222222222222223444-1--1333233333333332232222222--222221212222---1-----222221111111311--1-----11111111----1-------2-2-2--1-1111111111-123111111111113213233223----1111221122--------1-1-------------------------1-----1----321 ----778-733-23424445443633533434444334343344333433463543433343433212-42233312-11233334-2435443533233344322-5CAE9E9KEI88777D9PN7G9e*E1EDN6877E899468875A67I899C96AB9A874A584BDA62576I44469A8CC5AA82D9EA6 -----------------11------------------------------------------------------------------------------------------------------------------------------------------------------------ * f.20.1 Clc chloride channel
[ 503] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------1----------------1-----------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1------------------------1---------------------1-------------------------------------------1----------I-*****peJGMIMSNdfKbN**Y-mSpHQIEbHQaIBPKMFPKCmOcLQXCNdl**E5ODCtx**--21-----2----------2--11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.36.1 Neurotransmitter-gated ion-channel transmembrane pore
[ 504] ------------------2---111221-1111111--1111121-11-1212-1-1-111------- 3232322222222253344-4333334444423333456A322223232111243323--22433454443222222221223222222222-2112--121111222111111111111111122232223232--------2122222222222322222221222222221222231222322222233322222222222222233333322233333331111113322222222222222122222111111111111111111111111111111111111111111111111111111112111111222111133322222222222233222111323113434344333343333333211421566522222333332232222344444444444-2242222344215556555555553353424333334522222222254433434---11---11223222232332222111123333344443555555444445555444545655565511555744644445433444334542333332332345395324331433331455254332443424532111111111111111111-21-11224425344343344445433444345333441-24342------33333323334342333-3334222423333333333433334343333222222343332533232232-4444443344451113433335555237362222321111122223333333333456666454644454455522222222232434555543354444444444443333--43445544222222221-1-------------------------31133322223411 ------1-2------------------------1--1111211---1---1--1-----111-1------1-1---1-1-1-------11---121-1--1-1221-1--3142131121111123211231-11211211111111111111213222131-312------222---------1--13-1-1126--- ------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------1---- * d.194.1 CNF1/YfiH-like putative cysteine hydrolases
[ 505] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111222111111111111111111211111111111111111111111114111111111121211111111111121211111111121111121111111221112222113322323251211111333112212211111121-11111111111111122212111111111111111111111111111112222111111111111111121111111111111111111111321111111111121121111-1211111122221111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111121111111111121112111111111222111111112111112111121112111111111111111211111111211131213322132332321121211111111111111111211111121122212221-121111111222223111111111111111111111111111221111111111111111111111111211111-111111111111-111111111111111-1111111111111111111111121111-111111111111111111111111111111111111111211111111112111111111112111111111111111111111111111111111112222222221111111111-11111111111111111111111111111111111111111111-111111111111111111121111111111111 33112272833255322212222222322222234312222222222221223212221311212232222-12213122222211433253234522224424362572EJEGGFK9C7A9DBKNCTDZ*F2IHeBD9DIBCICCDFABCA9KDFAEC7DB8B9B9M6GJAE754353d433435A8D2764563334 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.16.1 S15/NS1 RNA-binding domain
[ 506] -----------------------------1-------------------2-1-----1---------- -24-4----------------1-----------1-1--3--F7I----------------1---1-11731----------2--------22--11---1---1-1------------------22-151--B27-11-------71M276511---------1-1438----------------------------------11-------------------------1------1--------------1--------------------1----------------------------------------------------2--------------------2---1---2----1---------1-1-2111---------12-1-1--1-11-111-1-1--51-1121---1------11-------511--111------------------1------------------------------------1-1--------------1--------1--1---------1--1---11--117----------------142-111------------2-11-21---1--521------------------------5-1----112--------22--------1---1---1-------------------1--1------------1--------------1-----1-111--1-------------------------1-1-------------1---------------1-----------------1-----------------------1----------1-----1--1-----------------------------------------------------------------1-- ----112-------11-------------------------------------------111---------------------1---11-----1------------6*-*LONOWUGGGGIQIYTFbG**P2RPXJHIFOIJNRHKIJIODHLJTSMVB7AE**9BGGGH36DD14421--1--D11*-*1--7F8A2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.23.2 Toll/Interleukin receptor TIR domain
[ 507] -------------------------------------------------------------------- ------------------------1--------------------------------1---------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------1---------------------------------------------------------------------1---------------------------1-1-111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ---------------1--------------------------------1-1--------1--1---1--------------------------------------------368-1qdbaZczU*qd*g***5***dfYR*gl*dOgaLTxRW*L-1Ig-----31-------------------1------------- ----------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------- * a.28.3 Retrovirus capsid dimerization domain-like
[ 508] ------------------------------------------------1-------------1----- 1--------------------------------------------------------------------------------------------------1----------------------------1-----------------------------------------------------------------------------------------------------------------------111-----------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------1-----------------------------------------------1---------------------------1-------------------------------------1---11-------------------------------------------------------------------------------------------------------------------------------- -11261C-1--1----1---1111---12-------1-----------3-1---1-----1-------------------1----1------11----11-------1-1*Vdc*pZNDDDQPIvgEjJy*X2jUuHGIBUJOjTFRMEBx9EoBeMMZQ**K*KG9EB9zAB*V--112-21--5946-4--1----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.12.1 Head and neck region of the ectodomain of NDV fusion glycoprotein
[ 509] 22-2-122222222223343443143355534-1---1121113223314734133233436552-43 6552521322211132222-23--232222223343323434462222311-112121--66323534664--------2214452215566243321-1212-42442--------------1443534443346666644453643333433332222223333333212111112111111222113-3133333333133333322221233232322111111112213333333333333332333-----------------------------2---211-----------22222222222222---------266-2-------1-21---1---252-161-2333322-1445346245-533122333343344655447564444444444444-33333442453146674755446642233454545533211111111432-13452222222233222211122222222222212422-2332442222333444434355552542242211232222433322252224421231111111134552422534211232223-32344434744543A44121111111112222222221131322212-3112-11------31-----111-361--652311111112321132221211111-2222211221212122223111212121112221221212122211122221-332333322333111422221222231242----2----------333333311141444433436545433441111111113-1113332212-1144435225551111224-222222--------2---------------------------32754454341421 11--221-2-2-----------1----111--1111-----------1----1-121-----321----------------------------1-3-11--1---1--2153656492----3253-42EM5-534212232342--2-23--3342244643333121-3217-2224o4322459AJ-661----11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.34 Formiminotransferase domain of formiminotransferase-cyclodeaminase.
[ 510] ------------------------1---11----1---------1--1-11-------1-1------- 5B6111--11-1-112211-12--23111111333311212211-1--2-1-1--11---11222224521-------1112-61112BAC5-622---541-173557--------------1---2123416133333444217342444--1131-1-1421333223----1-----111111BC1-111111111111-111-1---1111111111111111111-1--1-11-11---111---12111111111111--1111111-11111111111111--1-----11---------1---111---1111188164664566545346612216243351233443746771333232114-4322411111335453255454722222222223-44654856553165557687768894423232675532311111111444-2453111111111111111111111111111112445214322274456743333456788884856A44651233274122243462456435425111111122555416437-42-42221-9996D8CA9222233EB1--1-1--1---------------2113262358442654555555555556364571-1444411111143232434443433354-4544353434434444444444432324444444444444444444344453-222222222221111511111111192826---1-11----1--1111111111143222234414333321113111111112A77822222BB688112222222212222134222222--------212---------1---------------5B455868794623 ----111-211-11111111111111111121111111111111111111111111111111111----1--111------1111111112111111111111112-111115211-111-11111111391-112--1-11111-11--11-11-11111112121411311111111H1112121341111131111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.15.13 Nqo1 middle domain-like
[ 511] ----2--------2---1-----3-22--2--27269--622424221-686H-3-----22-2---5 122--229---4-7---22-24--1-23222-24242-2--654-6-44----232----2-2-4-31212-----445348---2-4-DDD--3-----3343-622---------------12464A9--914444-61--4-6-58989--22------443-6974--2----------4-11----22-----33----2-----66-----5621---4-41-422-44446424444444-2322---4-3--45--286-7-7-2--2-21221143332866869698883333333333333-89673777217--2222-42132-4-552-2---4-922D3--55--745222-222-244A2223-----24212-5--2-2-3333333333----1-------32-----224--22-3-22--1--4-44287888888---3-----------1----2-24-2--2-22----------24---2---2-----------3-21-22132-2--2-4-4322--438-C--C2622-245---4-6215222-6H---8-3643--422A--C3212-2122-2245-423652359A79B7854-2-AA--83B1-2-24-96-B44-A-44-6-19-2--2E534-------216A-3224222224--22--246-222221-22-422-4432122321-3242-2222-222-222-------5----232--1---------293322666332-646686B2----143482142-42-2--22-2-842-511-17-112-244323A252226-2255754448475--2411--f7--------6-5-1-5--5--AC22---4-4HA-5672-4-2------43- -1----1----1--3-1--22111-1-111--1--1-2121-----121-2114-----111-1--11-------1-1--1--111----111253-----1--21-41-5122-111-2-12-51-3-4B33317---1-12-1-2-221--1-11---1--1-41-31F--1-1-5------1-1-1-3---1-3-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.287.1 DNA methylase specificity domain
[ 512] --------------12----------------------------1----------------------- 11111-------1-11112-1111111111111111-1111111111111111111111111111111111111111111111----------1-----------1--1--------------------------22222222223333333333322222-333333331211111211111111122111122222111111111111111111111111--111111111-------------------1-1-11-1---11111111----1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211--1--------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------111111111111111-----------1--112-----------1------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------111111111111111111-------------------------1111111111---- 321143219461116545666666564557767675466665655556656656776667774454443444342554554334434555844565555434587818F4JGHGPHPDDECESA**DcHz*T4NQsCGIDUFENC8FEBAPBBbGIHECCB65AAG7C76D65D61474V46474B8AB6H43238556 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.68.7 R3H domain
[ 513] -------------------------------11-1--------------------------------- ----1----------------------------------1--------------------1---1---------------------------------------1-1------------------------------------------------------------11---------------------1-------11--------------------------------------------------------11-----------1-------------------------------------------------------------1-1-----------1----------------------------------------------------------------------------------------------11111111----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------3-----------------------------------------------------------------------------------------------------------------1111-----------------1---------------------1----------------------1--------------------------------------------------------------1--------------------- 1111pXZ-845-55544444444454444544444445445444554456655555458565545444244543554-4444244444436445453444423433-UF8bKVRUQSMHDJMPLSRHtN**R1UP*JLMMSMJMQ6MJG5MIIyLOMNMIz*DTH43F8DK84QW2324A2233343874351456888 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.64.1 Mannose 6-phosphate receptor domain
[ 514] 11------1111111---111---2111--11----------------------------1111---- 1212311111112132222-211122222221333323531333233322124353332233323273333-----------4-----11---1--2113334333313222222222222221---1----11-57633---33111111111111111111111111111111111111144444---224444444443443444474464444455344322222242233333333333333344432-1-22-1---111111111111111222222223322222-222222222222222222322222222211---2222222-2--222---------2-------1------1122--23-2411222222124223222222255555533444-225225232322233231533343233234242222232222222222221212211122222111122222222222222222236831232233332243333322233333253333333232232222222333222211112222222221224222-2-1----------2231324--113133-21-----------------------1113223323343334333333333333333431-1432212111132222222222233322-222223322223222222323322222222222222222222222222222212222222222222223333333333213232222222222222224444424222324444333333333222222222222211223222223323333333332222222111-222221----------111111---211--111131-11-------------1323 22--343-313-3323222343333333333233333433332333123333433331233332222222222222222221112222233323434333443443-24362433353133333543417U3-53A2313333533332333451742338634231111A43234423e2222468B93654332223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.9.1 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
[ 515] -------1------------------------------------------------------------ -1-----------------------------------------------------------------1-------------------------------1--------------------------------------1----1-------1----------------1--------------1--------------1----1-----------------------------------------------------4-2-11--------1----------------------------------------1-----------------------------------------------------------1-------------------------------------------------------111---------1--------------------------------------------------------1--1------------------------1---------------------1-----------1----------------------------1--22--1---2-------------------------------------1--------------1--2------1------------1---------------------------------------1-1-1---1-----------------1-------------------------------------------------------------------------------------------------------------------------11-------1------------------------------------------ 1-1-1-1-1------111-----1-11------1-111111-1--1--12--------------------1-2----------1-1------1--------1---1-21-Fvss**tURSRUWZ*oQuR**kFtf*EPROaUZYSGXYPPdOG*WaVXR7F5FCAD9L89K7B55---11---1-2---1321--1121 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.69.12 Sema domain
[ 516] 222131111-1-222-13111226G-2C698A137-221---155-856AMHC145884632225165 -15-2122-1111-1------1--11-----1111122121343235---1222211---12216--54532111122---2-1-1--4432-212----1-1-23322211111121211111-------1-113--76---5311--1111111------11-1211-------------32434---1-1-----------------11--1---1-1---------221----------------------1--1----22--112---------111---1-------------1111111111111-----------1-------------2----2--4-2112-1-133-1-3211--------3-9-----------1-----------------------------------11-11-111---------1--11-11-------------------------------1-----------------1--1------1----------1-1---11----------11-2--51122-----2-----------1--1--1521-1-1-1---1--511114--415385------1-----------------------11-1-21---1-------------1------------------1------------------------------------------------------------------------------------1---------1-1---------------------------1-1111-12-1-----111--------------11111----1-121111-----2----111--11------------------------------------11-11-112--21- --21332-2231-13222152322332222233424211111132246324326334212222---1------------------1---1-22211-----2-253-493WNTTSfMKGIHIQGZdGTKi*P-ePrJHGGTJJdMDMECDQCFcJKMIiAMA7CEOA7CEV1274-4235-12-11551-11--1--11 --------------------------------------------------------------------------------------------------------------------111-------------------------------------------------------- * b.1.5 Transglutaminase, two C-terminal domains
[ 517] --------------------------------------------------11---------------- 2221211111122132254-42223455555244442233231312212121121212112221412312211111111111211211111111--1--1111131121--------------122111112122122231112135352221111111111311244421111111111111----111113222226433545335131222554222233332222211111111111111111222111121111111221112111121111111111111111111111111111111111111111221112221121111111111121111111111-1--122111111111111--11111312222111111416343234263333323232332-33233533434263322254333453243222523522322222222244241421111111111221111111111111121122214332233155453221222243222213426283513222414115433323332121221122221124111213111311222221222332233111113211111111111111111111111111441212222174343333243333334323331-1111111-11132131322222222122-2222222222222222222344223332221222222212112213111121133333233333311121111122223142211111211222111133424241113233233753233332212211111111123341111141311223333422211111112331122----------1----1-1111111---11111111111111111112211 11--452-721-225247557979G993325343537646442422575D56A8337644432113131133132332132122123329E543534332222523-652B4A88632311455553627K7-444112141264232-252-74632622236331313243382134M223-4968B72812452-2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.93.1 Epsilon subunit of F1F0-ATP synthase N-terminal domain
[ 518] 2211322-1-111111--1----152242596--1332333331223125656-1212222----213 334-1111--1-1-11111-12--1111111111111222-21212111111---1------11111231------------121211334423111--2638444254--------------152-11223-44111--1112-8GD6A953222242463683567541411111411111121111221222222222122222222113322211111111111111211111111111111112221111-11-1-1-11111111-------1111111111-----------111111111111111111111111211111111112121211122212111111111111211111112-112116122412222312111111222122-2222--13-11211211342-5552665897892154454233339473333333322232112------------1111111111111----142322344356776764322255563333336467777-144422344421331246341243111111111241246645233247111111142536411113513322322222223233333333353511551A4964A866555547755547366456--1431511111165343656777677777-77777777677776767767774422587778788888787786656656521544444444444112512112222226444333212111112111333333324522666676964777646673122-22-1268743333374454333232222222221-11--22221111111121--------------------------1111111111-121 -----------1--1--------------------------------------------1-1-------------------------------11------1-1-1--1--------------------------1--------------------------------------121-11----25217-55-12---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
[ 519] 11--122344444445-22222222---1222-------------1-1116---222--11331--11 32--112233611253111-14--3411111253244477-423422113312152-3--1112215422211111-1---13-1---3363-1111---312-32413111111111122221111---1111--1121---3272423352222112111222344662311222241221-211---22122222322224222221332122211--21122222212222222222222221211112-111111-------111-111-111111----1--22222222221---------------------------1-------1-2----1221111--11--1-------1-111------1-3111----1534452233322311111111112-54333233----11112224431124--121342214322122222235522142---1----21-1--11-11---11-3-33-1-1---33112223219111122161112-1-434221--33-352--211-21251-22311111111111111131-122-------1-------2----1-66------1111111--1111111-------11112323212--1--3--11112---1-2---22-2-1-----222-11--1-----------1---------------454-1-2-21-13111111111111------------------------11111134441-232111----1111---165646351-12166777777386793567----------111122222131-111222225332111--11442222--------1-------------1------1-----------1-1311--1 3111134-B2--3264465723243623333332321223422465355548694436253545634445563536647643343554538544767553222589-1I6EBC54794376486EC5D5OrB-C9H4464A558547663C53A5A646752867B4F67325632457J45383969C7A9A646516 ----------1-1-1--------1------------------------------------------------------------------------------------------------------------------------------------------------------- * a.132.1 Heme oxygenase-like
[ 520] ------------------------------------------------------1-1--1-------- 2222422222222243233-33114434444443334444222232332222222222224423424555224444222222212222222222222222222223222222222222222222222222222223333322212222222222222222222222221222222222223233222222223222222222222221223333212222122222222222122222222222221222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222-2222212222221222222222122221222222222222222222222222222222222122222222222222222221222222222222222222222222222222221222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222223333333212222122222222222221222222222212232222222222222222222222222222223322222222222222222222222222222-2222222222212232333452323133-4333334333433332332333333333233333333333333332222-222332333323333222222221222222222333232322223223333433322222333333232222223332222222222322233333333332222222122222222222222222222222222222222-222222222222222222222222222223222 21--111-2---2222322222322222224232222212222222212222222222231332223221222222222231112211112132131223121223-14113623314111-21453728K2121212112-242212342422232242-11311-312111313334J4423363342341221111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.325.1 L28p-like
[ 521] 11--11847777777A276462343111--11--53382222241-2-417762-2-222-1351--1 2-151------11123222-22221322222321213775151311--311-32233111224-1-1235211111112111-5C4661122-233------5-21-2----------------16755745634333441111414--33111111-2---121-----1----11----121211441221--1-1112-111111--22-11112311131------21122111211122211112--2---21-----11--11--21------------------------------------------------1-22-433333323231233123131411--2324533323235-15243-1222---------165422321232------------143-6-41-1--1--311-311-1111112111211335111111113112-711-----------------------------12112--1----1121------1112------2111223212211313131231-12-A11-12----------1-2-642135634654413233122435444122621131111111-1-------31323995645615454357777469777556675653--176G33333355357648888888888-8888888888888888887778566655655555555545455566777783-477777777777--35-----11114764544444433332433433333332323466766555565654543---------83335444444434411215111111111455211------------4---------------------------211114444411-- -1--112-322111111111111-1-1--11111111-1----1111111211111111111121111111212111111111111211---11-1-112112111131141112-22-2-12123-223N11125111--11-1-31--2-13133121--2112--232131311-1D2111112121112122211 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.114.1 DsrEFH-like
[ 522] 11---12111111112-132231111111211312---1--1--------221-111----221--11 1132721233321242333-33223433333322222483242225211231323225--222232444411111111-1114113331111-1-----1211111211--------------12222223222211111---42221111111111121111111111111111111111122111---32322222222222222233332322232322121111113211111111111111111121-----------------------1-1----11112111-1211---1-------------111111111----11-------1--1-221---1111-142--1211-----1------21-1433311111214331122211111111111113-11212312343134412333341111132213111112122222222211111221111111111-1111111111111121211112112534555544634455337744442353A6B871244221122421155225112122222222211211123422-21-33----222241311111123-2311111111111311111112111211221233223232222222222222233222--13222------31111113333333333-3324333333333332333333223313433333333333333222222221-111111111111--1222222222212522-----1-----11112231222232232222222222222232211111111111213222222222222222222221111112-222222------------------1------------------11-21-1211111 321-652-7211665555344656766333333333533343343434354454464543535222211233221343332111112334945645233455223315248643356233234495362En7-71B43555357547525732433A4437855544648D88455553i34254B4884984154525 -----------------------------------1--------------------------------------------------------------------------------------------------------------------------------------1---- * a.103.1 Citrate synthase
[ 523] -----------------------11111-11111111111111-1-1-111-1111111-111----- -------------------------1------1-------------------------------------------------------------------------------------------------------------1----1------------1-------1-----------------------1-------1------------1----------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------1-----------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------- 1111111-522-121322122223232222333322133333322312342354222234333333331342343441443444454553432353222232377522118RZ*m*TOJGDIMGsyFjP***5*WuQGKCfIMbKJNKJFbGFcFQCJ*1-1B241142123341121183111135342B24234442 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.16 PAP/Archaeal CCA-adding enzyme, C-terminal domain
[ 524] ------------------------1--11-11---1------------11111-------------11 2222411111111122233-321122333332222222322222222211114222211133212232221-----------212111------------211122322--------1-----1---------3-11111---21233333211112223222222433312221112121311211---3435555556535565453533345544444545222222851222222222222124222222415512212333344211---111---------------------------------------------11-11-11---111-1---133-1---3--2-21---------------212222222222553442224444433332333333-33433433242222234443333355222223333322222222222233133341222222222222222222222222222232242322222222222322222236222222256333222222633333623332233333222222222222244121-1111112222----1-1---222233411------------------------543343333333333333333333333333333--342333333344343434444444444-444444444444444444444444444444444444444444444434444324444444444443333222222222533333333333333333333333333444433333333433333433322222222223333333333343344555554445544443------------------------------------------1----------52-1 33--222-72212322222222222123323222232212222222222232223222221222222312322222222222222222212222222222222333-25234223211222223341236F3-435321221232222222332433232122211-224513322332S2223375591455352323 ------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------ * b.124.1 HesB-like domain
[ 525] ---------------1---------------------------------------------------1 --1-1-------------------------------------1-----------------11----1--2--------------1---1111-------1---1-1--1--------------------1--1-------1111-4113--2--11-1------111131----------------------------1----------------------------------------------------------------------------------------------------------------------------11--11113-11---1----------1--1---------2-----------12222-----1111211------------------11-11-11----1--1----------122--------22---------1121-11-------------------------1-1--32231-----------1111----2------------1---1-1-1-----------1--1--1111111-----11--13-1--1---------22212------113211122222122222222212-21------11---------------------------11--------------------------------------------------351-----------------------------------------------1221----1---------------11111------------112-----1111-----1-------1-----1---------------------------------------------------1------1------------------1 6444866-QB7196B9866B626869A577B89A996696878567797B798868797364536363-48554579378644564754766896B464586458713b3MIKHJMJCCEDEIGLIFPDl*M1SGUC9CEJ6HHADFAB9LCDPCMHDA8JEC9847AFAVBMC71CC9f497C8XCCLBOCA969AAE --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1- * a.159.2 FF domain
[ 526] 33111221111111111------363467676354554444445647544786323342221----11 2174B2111112--23222-23--1222222122225364354346333422453222114363323553322223223122332253424315322---313221423-------1------1221222222325558A2225533222222223111111222323211111111111113222244143411111221213123244333221533334212222213B233333333333333222221332332212122223321212-22212212321322121121111121111211111112121112223694669999A899A958446886B4913642644466447674A7663253532223-----1-21-1-1--11-11-1112-1-11---11111111-3221223111221321----1-22-11--------11-1-21-11------11----11---------1111---1112221133644433333445342325454223321154243653324243224311111112222211332228541665676666354633376466A6353311--1-----1-1-------12124552242221241232222143222342343331-114311-111143233222222222222-22222322222222222222322212322122222222222222222222311222222222222--11-----11114122111111111111112111111111111134232222222223222---------1243522232343331111211221-----11122--22------1-2-11111--11-111-1111--12111-54456555547421 ----231----1111-13-211-1112------1-1-2122221211--1--1-212-----311-------3-11--11-11111--11-111--1111-11122-----11-121211-11111-3-692-3231-113-111112-211-411112--1121--11----2---1-----1-3214-251-1212- --------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.6.3 PHP domain-like
[ 527] --51-332A34B88WF-63-2V6-A8A7E7LU-4-123-----211-1246H61342172614A4-1- 21--1-12---1---1155-54--1154545132222199-19R1121-111111--1--332121C4514----71--1-2-2--341111-1-------------7-----------1111------------7-12----4-23e5RL*j*1111----22Y1CP24-------------68----13G24545568D45533682-2212446bA121F3-11111611111111-11111112112216-21129-Q2115533-3------------------------------------------11---111-5412211111151613B44174N471-5-121733E21--2-111-6--6----11--------111---11--1-------1------2-3111--1-111111111111-1-11-2-----1-211111111311--11-------------------------------1111-11-11977-39-1111--11----1-2-1--1---211------D1----------------------3-1-22---2--1-11--11111112-----1111---------3-2-51-----1----3-1--13-11251--------3------------2N-1-------11--4112333212143-33253224243142222221111-11C1-1211121112222242222334--111111111111---111--------1121--1111---1--541211121112J512222----1-----1----------------------1--411111111111-32----------1--5--1-----------------------------1-54-82846D2-- ----1-1---11--1-21--222---11111--1111111111222111-1-11--111--11--111-1-----1--------1---111121121111211111-11-3221123212-4322-1414C2-44511224123-2121211131-22211111-3---3--1---XL241--U4EIJW1QC1-2-241 --------------------------------------1----------1------------------------------------------------------------------------------------------------------------------------51--- * g.72.1 SBT domain
[ 528] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------3-------------------------------------------------------------------------------------------------------1----------------------------------1-------11------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1---27W-2-----1---11--------------1-----------1---1-------1------------------------------321-1-3-----1-----r16*mna*pWOKPMPQPjkHoQ**p-*c*MMNPeNVdLGUQOJcKL*UgMSVCMLI9I89fE8U7G3C-1-11151-11--1-----154G3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.3.9 Growth factor receptor domain
[ 529] 1113112222222222-2213115211111111111121111111112-2222424334432--1-21 2131422222322222322-22113222222332222232122421223232222132--2322333553212223321121122333343313221--34433333341222222111----211111111211444221114222222223233323233222232223222322232233443322226489989977799887745544477A656565644445456333444334333333333433-2-32-42-1322233121-21211311----111------------------------111--1111-36343663453436434654222324--41132444633224344331133152222-11-1323333233343322222222212122222222223-2333332333222332322222222222222222223322322-----------------------------2222222222311121111111112211111111222221111121122122221233222231221111111122211112221111111-2222232231122221132223222222-1-------21242112223243233222222223222222222221--143311111122222222222222222-2222222222222222222222332222223232222222232222222222-22222222222211-3-----111132233333322122112113222222222233333334333333423431----1---2222333333222232222222222222222233333331111111111--------11------------1---12111313332213 ------1-312-11121232122241211111121112122211111111213111222211112111-1111111111111121111312111111121221221-2412112114213422332131352-324523222443134123-121312211--22-1-1-1-33-1132B1112155673552312222 ---1-1-1---------1-----11------------1----------1---------------------------1-------------------------------1----1--------1---------------1-------------------------------1---- * a.204.1 all-alpha NTP pyrophosphatases
[ 530] -----1------------1--------11-1----1-------------------------------- 334------------------1---1-------1111----321--------------------111---------------1111--111-----------------1---------------1---------1----------1--2---22-----311411111-2-2--1-11-----1---23D-------------1---1----------1---1-------1--------------------------------11-----------------------------------------------------------1-1-----1--1--1111------11---212212-11-11111-14-117133335331112231-1-2--222222-2121----4-32---3--3-----2---11-234311--1-------------11221-----------11---1-1-11-11111----4-323-2--13979BDDA98877698BCBD78DE73629-187GA344566567A221886B5-4IE56CA787B45334451---13----5555855B645346251-1112--1------------1-3111-575458558666688745667864677775--12556------514713547764BAB79-844897F7777B7A54AA7454652343221222232232312464721221-C77699877A98--97122116666349212-246232125-GH34355437373568AC8A678677796243432123123388577777755755A877676444A888--1-222222---------------1----------1-------------------121- 1-11--2-3-13---111-1----1--23--1-1---------21211----11124-111111--1--11-1-1------11111-1-2-11-2311121311----6331-132-1211221311115P2-2-1-21-1--1323124-311321131-113212312-1111-5427--411-235162113--12 ------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------ * d.24.1 Pili subunits
[ 531] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -1----1------------------------1---------------1-------------------------------------2------------------------is*o*iaVLOGScQ**M*T**d8*k*OSLOwQXoRAURJEgLHzQZWdSANI6MHA4D66KAB92------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.76.1 Hormone receptor domain
[ 532] ---1--1222222235-32331-131111111-111-11111--1---------11111111----11 232261213361128BB66-6C2269656666BCDDACHB153713223111224313--76B22255431-111111-7ZC411-1122222222---1211121212211-111111111111342222231123322---2122-21122222222211-21122431221122211112211111-2212222211212221121222122221213122-1111-111111111111111112111111-311212-21----------------------11-------------------------11---1111382221111111-111132--1-111--12214JF2312112----2-11222222211111537582322324211111111112-43433634342122222222222227332213213312311111111222-222311211111111111111111111111111218A215654343365322222552822221253466872244252133362355113322132-------1223231311-111212332-321341121331324121111-------12111111112-11113332112224254444234445746437541-13123------22551332223232322-2222222222231222223565443313233333333343433211211112-222222222222--2111111----111122221111111-111133223222116233132231145551222111111111133334434433333----------1111221-331121-11------------1---------------1----------1---2112 11----3-421-11123222231334333111143233332332331111237B2111121113211212111111212214433311147332352222211314-1122211132111-12-12-122H1-23211-12121--1-1111-11231113-13111412E32121132N2233232462322154331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.168.1 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
[ 533] ------------------------1----------------------1--1-1--------------- 1---1212222-3--1111-12--1211111131111211--111-3-14442222-1--1-27111121--------7--1-----------------------------------------------------111-----3-----1--------------------------------222--1--326444443665543437G8A8954543562635HILNKI3217777766767777632223E2-1CJ1-314CB--GL2243152555956666556B99AABC98A9666686666666655511-555715-4I4444444544-P--1344-1-13312-----------18861313-----------------------------------1-------1-------------------------11111----------1---1--2-------------------------------------------11--1111--111111-2-11------111-12--1----1-------2----------------1-------------1-----------------1------------------------88B------15--------111----------1----11-111C634373DCCEDDBBCD-BECDCBADEECECDDDDDDDEH98232D9AA9ABCA9BBDBAB7BA8AA993-656666666646--1-------------2-44453411111123411111-1---2-22322323222222222----------999A999998A8AB1111211111-------5------33323222-------2-1-43321444144341--------1-------- ----1-1-21-----------------------11----------------------1--------------------------2---1-1-----------------2-------1111-1-1--3-1-1--1111--1-1------1--------------1--11-----1---1-3--2--1------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.44.2 PTS system IIB component-like
[ 534] 2233222222322222-22222241111121133544353543222224344442222223222--22 2321611122111121211-11111111111111112111244321111211211111114511423334211111--111222222211111111-1-121112111212111122111111-111111111311111111131222222222222222222222322312221112122122222---22343434333233433353333343423233111111114311121222221112211111113222211113211222132121-1111111112121111111111111111111111121111-111123212111111121223332111112112133333333332432112112222222221111123111122533222222222224-112112123221234322333245221112142222111111111111111222322222111--11111111111111111111123122222232243332333445522222332A334311222341223213212222222342222222222522123223222432221232232222222211132233233333323222222222322223333322322332222333222222322331-12223------44322323444333443-433444444444433333344433322444422423324444333344442223323333333331222111112222223323322222111122232222211112222222223322222222211111111112323222222222222222221121111112122223311111211-------------------1----1---11111111112111 1111111-521-1121234436246462322122422232222222423563453322222222522213323234425435534221212222312431111221-15124111111--122213111161-113-11111114111-111144111411B1-1111122132111126111-133392311131231 ----------------------------------------------------------------------------------------------------------------------1-------------------------------------------------------- * c.34.1 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
[ 535] 43--11-----------1113-4-6111C424---2V9------1-1--1---8GDH4M8C------- --222111111111-2244-4333-244444-3414211313212-1-1111-121-11121212112113122231111111--32--------------------3------------------1----114----2----4--135---1111------1313151D-------------12452--12133333311133243311111231211113212111121111111111111111111311211111111111111111111111111111111111111111211111111111111111111122111111112111221221111331132113112112222421111213311-1--2--------------1-------1--1---11111-----12-------------------1---------------------------1---------------------------------------------1------------1-----------1-----1---122-------------------------1-------2------------------2---------------------------2-----2-------1---------------------1414-------1-----1---1--------1------------1-------------------------------222-------------------11111----1---------------------------1-1------------------------------------------------------1---------------------1111-1--11-211-1111111111111111121-2---- ---1-5A-3312645115224421112MLN46A24221-11112335W21312111244211G-B-3--1863-23N2226---222-51111123131134164D-623HFFGSGQA89AAEDVT7RCp*Q8ZJU6A88G9DGB8BE97I7ASADC9E7GL6C752A76H9BB5-366K12-23G32F34B-1776C7 ----------------1-----------------------------------------------------------------------------2-------2-----------------------1----------------------------------------1--11--- * d.95.2 Homing endonucleases
[ 536] --------------------------------1----------------------------------- ---------------------------------111-------1-1-------------------1---2----------------1----1-------------------------------------1----11---------2--------------------------------------1------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------------1--2----------1------1--1-1-----1---------------------------------1--------2------------1---1--1-2----------------------------------------------------------------------1-1-1111111111111-1111111111111111111---11-1-1---------1-1----1111111------------------11111---------11111-111-1111111-111------11-1-----------------------1111-----11111-1------------------------------------------------------------------------ -1--34--G69-FFL2--41433313112211111332321222323251242222433--2-21121-2--1212--1--1-11-2116B1-7135543115B7A-3RE8331-344-54251252625G2123924-144323153214223-6331--112121332---224229JA7776****-**A973481 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.17.7 Putative dsDNA mimic
[ 537] -----------1---------------------------------------1---------------- 3331222222212122222-22112222222122222222222223112111121111113221211222122222221112122343111111111111111111111222222222222222111111111112222222221222122232222222222222222222222222222222111222111111111111121121221111111111211111111111111111111111111211111111111112111111111111111111112121111111111111111111111111111111111111121322222222221122221111221-2111233221322212221211122222211111232223223333222222222222-22222212222122223332223233322222222223222222222222232221111111111111211111212112111112322232333333333333333332333333333222323332332222333333243333233333333233333334444643444441444454444333323242232111111111111111122122443333333343333333443333332443442-2333311211133322332222222222-2222222222222222222333224334333333333333333222222222122222222222211232222233334333333333323332333333333333333333333333333333333111111111333332222233333333333333322223331332233111111112311111---------------------11111211122311 1111232-3-121221122122122212311111111111111111211112111112211211211112111121222111111122312111111111-21312221132444433142222BA283Kl6-82E2332323511213-5138233341132111-111343212122F2222333362762353332 ------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------ * a.173.1 Poly A polymerase C-terminal region-like
[ 538] -------------------------------------------------------------------- ----------------------------------------------------------11---------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----1-----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ ------2-21-11---1-1-21--1-12221-2--11-1-----1--3--1112-1111-----------1----11111---------1211211---1--------41mRZhVUWVPKLVhV*zT*U***1*j*PXSKpVUcXIUTLJcKGRGSQYcLQH5GC95D6AD6MI---------------22---1-211 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.7.1 Snake toxin-like
[ 539] -------------------------------------------------------------------- ----------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------2---------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------1------------------------------------------------------------------ 32-15B6-41232254334332321233313333331222222222333323333334444422222212222322222222222222223334433332222211-F25TVdYcRLOLMEQbSuoHwK**nAqe*NQDHbOUfIGUOGHdKEmTWUQbAMN6DE75D66C7AI21121913-2223543511223241 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.29.7 Mob1/phocein
[ 540] 221222222222322211111111222222222222222222222222111112111111111112-- 2222232222222232222-22222222222222222222222322222222232322222221321222222222222121122211111111111--1111222-32222222222222222111111111122221111113222113-11221121212112114111111111111111-112211-111111---1111-1121---2--1---1---11111111-1--1-1-21111111--1-111122111111111111111114431111111111111111111111111111112111111111111113-322222222232111113331121211111113122211-111121-111333333335334333333534355555554545-333353334433444444544465343334444444444222222222222222222222222222222222222222222222222223222212222223222222222222222322232222222422222222222223222222222222222222111111111111112121111211112111--1111111111322223223-2211222221221221222222161222222212112-2222222122222222222222222222-22222222222222222222222222222222222222222222222222222222222222222112122222222222222222222222222222222222222221252212322222222742222222222---------2----22222222222222--12222222-----1--1111111-------1------1----------------12-1 1122343-3111222231-1322221222111132221111111111112111111141111111111111111122111112121111*1131122222111111212322212-22211121221328P4152512--121V11111-81-e1A4143484536-212433522211811111412F11121113O1 ----------------1--1-1--------------1----------------------------------------1----111---1--------------------1-11---1---1-1---1-------111-----------------------1----------11-- * b.85.4 dUTPase-like
[ 541] 22111---1111111-1124211131124143112121111112211212221111111111111112 -2123-12222-1--6222-231133222222324215271-22231322214561-1--523211523311---111211231-11111111111-------1--1211111111111----12222221222234433--11454543343222---1113233554411---1121-112311122322322222222222222222223322222122223333333332222222222222232233322233222222222323221111112222111411111111111111111111111111411111111234233444444424223443222332333323344352222233323221133344412212324442222222222222222223-22322232242-3223233332223222222233332311111111143313343111111111111111111111111111111242212111133333533333442433333433313311154425321322313212222241222222232243213C4258357477B-23332335422322627---1-1-111111------1-2112334351212231332322322332333433231-2323311-11163332336666676766-5666766656566666665445334444333434433424334465455542-4444344443431111111111111135321111111111111113333323111413334454434333233211111111112224222223433322222222222222--23111111111111114-1----1-1-111111-1111--1---1111121111332- --------2111-------11-1-1-1-------------------1--111-B----1----------------11--1-----1-----------------------2----------------111241-2-1-1---1--1--------2-------1-1----------11222V2221-1352-221221323 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.8.1 Phosphohistidine domain
[ 542] 111-1111111111111111111111111111211111111121111211111111111111111111 1251111111111111111-1111111111111111111111111111111211111111131211111111111111-11-1111214442242212222222312221111111111111111111222221111132111111111112----1--1-111111111-1--11---1--22222111-13---------------111112---111121111111134122222222122221111211-----------------------------------------1---------------------------133-32222222323-21133322222121222332324111111211--212211211111114335423333322122222223122222222211121112231121111111111111111111111111222221221111111111111111211111111111112121133334333333333333333333333323233322223332222234334333222333333333433442334332222232222322223423323321231211111111112111111112112113322223343323223323223223243222-2241122222222332222222222122-2222222222222222222222224322222222223222222222222232122222222222222221111133332322322232322222322233323233323233434343334343333233333333222243333323333443333333333333221331111111111111121111------------1--------12211111111223 4322332-7223222222123223233332232333222222222222222322222222222223322232222231333222222222222243323321223322726342314424323356372Ib7174844434333433214343A1343249E26343212422522433f33333477B2654353333 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.53.1 Ribosomal protein L25-like
[ 543] 11-1111111111111-111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111111111111111111111122111111111-111----111111111111111--1---111111111111111111111112111111111111111111111111111111111111111111111111111111111111111--111111111111111111111111111111121111111111311111111111111111111111-11-1111111111-1211----1112111-1111111111111-1112213233-1-112211111---11-------1-1--111111--1--1--1111111--111111-1--121111111111111111111111111111111111-1111-111111121111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111121111111111111111111111111111111111--1111------11111111111111111-111111111111111111111111321111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111211111111111111111111121111111-11111111111111-1--------------------------11111-----1111 2222438-A36398C2211111111111111111111111111111-1111111111113111111111111111211111111111112222222222122366813F5JCEEEGGABFBCC7QOAKB**K-MBMAC7CJDCOGBDE86C8CK7EBBBFH86AB92445E13F72556z44432B6B815B3668777 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.58.6 Nucleoside diphosphate kinase, NDK
[ 544] --1-1--1111111--------------1-1------------------------------------- ---2322111112231111-11--14111111133313221---21312221434114--12224572431-------44653--1-------2----------1-----------1----------------1-32255777311-1--------------------1-------------3444222--326666666747666665344327664325467555556243333333333333334343455635643445882265475225756555644643333333533333474474446446457655266661644555555568671355555495-554671266-214942-4321321--1-----------12----------122-222-24-11111-1114--311-233552332----1------2----------2111---2-------------1----------------11---------112111211111213332112121111--11-2----1-4--1----211----------11--1---11--2-12222---------1--1-32-------------1---------1-----12-111-----1-----------1----1---1----------24--32-1111121211--111211111-111111112221---2-1--1-----------111-111---211111111111---------11111--2-111211--------1---------11111111-------1--22----------2111------11--22112111---------1--------------1-862A22-2131222---3332222224733223323---- -1--133-41--54343521211312422233211112111114233449346533423222415113-1321143213322113111212233514355111144123176656AI5666795JD6D3Pp51IEU44467289963783763O7745932258354-325641-122181311161192451246131 --------------------------------------------------------------------------------------------1-------1-------------------------------------------------------------------------- * c.119.1 DAK1/DegV-like
[ 545] 11-1-12222122222-3223213322332121111112112211111-----111111111111-11 2321611111111255544-47224544444445666476233223112111333313--444233355321111322-11222222222222222---1311121233111-11111111112344434334332222211-31222322222222221112222525212212222111222111221222222222322222222222222222222211111111-3411111111111111111111---------------------------11-------------------------------1--1------32-11----------1144-11-1-1--21125332341214----2--1232222211111434573422223211111111112-43133334272122222323332313222122222312311111111222-23221121122211111111111111111111122222111113333333222224423222212322323422443222222222433234221332222222222323246333333534441222232222333335262221122221112111111144434113322222232344444243333433334331-12233------33332323334343433-333333333334233333333333332333333333333333332232222213333333333331122222222222223122221111111-222133333222223333233232233232222222222222233334444433333111111111122222221332222-----------------------------------------111-12222 11--321-611-11133231111142122111121123331342221211112111111112112111-2211132212212222211111132161111121312-1222211133121--21231224R1-462---1112---111112121231213121153423923211122X2222242541532252222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
[ 546] 22111122222222222222222222222222111111111112222222222211111111112222 --3-------------------------------------------------------------------------------------4-36--------------------------------------------------------------------------------------------------1---------------------------------------1-------------------------44---2-----1---------------------211-----1-1----1------------------1-------------4---------1----2-21-1-13---1----------1----------53B3------511111111119------3---1--6--7C-834-9515-----43H-7---555555551----3-----------------------------------1-----2--262-F----11211----91DB-322--331---3337132---1----------------B1--94--2---A--------------2-1331-1-------------------------24---11----1---11-------3-----------3----------------EH6-132F1-D--2123--8F22------1-1--14--1---------------Gp3D664--------------------------------------------------------4-C-2-----4BC3-27Z1-----------*--F-----*--------------------J--------------------------------------------------------- 321244423--2434443344444444444434444443444444444444545234445343232221222322221122323234452534233222222242324427ABEH8G9BABAABNJAOEk*F3JBTAD7DC9BEC89E7AC96GBA8AA68A7448B966566413443244224C335464-136421 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.52.2 tRNA-intron endonuclease catalytic domain-like
[ 547] -----------------------211112131--1--112111211111-1-21-1--1-1------1 114-421655523253122-28--222222216464774723333445533-834131--1341212442222222321-113221112223-211---1423224332--------------132233322233444441113142332221211211122221255321111111111112512222-4323333334333343332333233333434411333333452232323333222323344411231132112112211-1-21-22211111111111111111111111111111111111111111111224212223422121213311113121-1431152112122122222--11-33222-----322222242222212221122225-46146441442-222133344121343-33144423243---------1111533------------------------------121311111374466632221AA955555247574143-26532313243332-4-5212121111111124143412331213-2111--1-1111121222212112---1121211-1-------13112111-12123121-1111122131122212412---2344------11-1-212221211122-22221212122112222211-11111-2121212323111112122123221---------------12---------13531---11------1112322332222341343333433322241121111111111-1142222232222442212211311111-1-221122----------1------------------1--------1-------3322 ----221-2111552223224323243222222332122221222322222232322223332222222222222222222222222323422222222224122213223232243123213244173JQB-6792222332E5-332132572232244212222835623242341H1112662242421354451 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.44.1 Phosphotyrosine protein phosphatases I
[ 548] 11----------1---------1--------12-2-----1-1-11-----11-1121111-----1- 6432323355411142333-36113733333165365547294724331452744433125133444226442221111112-----11131-322---44245234-21--------------11221211-1211114---21432421132---1-11111143322-221---2-12-2-11----3--1111113111212122-----111-1-1--1------1--111111-11--1111--11-1-222211--1222-3-1-1--------------1-------------------------1--------3--213432312223-22211--1-1111211-513-12-5--111----2-1733322222315774313963722222222223-22313933463157776678B344-52221422222212111111112135--3---1-------1411331331-1111----1334331----324424633332251333314353-121--2112-31-221132-121---3-1222322-1-3222211111-12---1-2-2----1323-2651112-------1--1--1----11-1-123432216454642555235644425444321-22221------22223111342111121-22113221122111111122224222312323231313323215--111122-1111111112111--21111111111122-1--1-1-----1---22111121223343333226333342332--1---11--2443-1--15444454544323331221--1-22--21--------2-22-8---11111--222221112222-----------2-3 -311124-735365A11-12---1-2----1121----1----2--3223225511-212-4-1--11----------2--11---11-4B414432-23121224-2P37462473424133397672Ec6185B54445444342554543B23574143223713122--521A95I34-34A79E-553847837 ---1--------------------------------1--1--------------------------------------------------------------------------1-------------------------------------------------------1-1-- * b.69.7 Peptidase/esterase 'gauge' domain
[ 549] 11111111-1-111112112222111112111111111111111111111212111131111111111 1221211111111122222-2211232222222333232222222212111122211111222-222322111111111211111211---1--11--------1-2-111111111111111111-1-11121--1111111-1-1--11-31---11111--11---1-1--111-1-112111111112222222222222222223222222221132122222222222222222222222222222111111111111111111111121111111111111111111111111111111111111111111111121-121111111111-1111111111112111111111111111112111-11----2-11-121111111121111111111111-12112211---1233111-1111122------1-1--11--------1--11-1-11111111111111111111111111111-1-1--2---1111-111111111--1-----121----11---12-111112-1121-112111211111-1-1111-111212111111122211122122222211121111111112-2121222-11--112231122111122322221222222212211-1-11211111122222222221222222-22222222222222222222222222422222222222322222222222221233323343232-111-----1222--1-1----1---------1-------211------1----2111----11111-111-122311111222111133333112----1-11111111---11---11111112-1121111111121111111-1111111111111 5533333-D43533357564454545544644444446566555443344545454445545333354333432644345343333645675775S55452365654354C996867442415464464CY7-95B344534444356225-344866722745654B55535434354P66544G9DC7BG3756775 ---1-1-------------1---------------111-1--------1-1----------111--1--1---------------------------------------------1--------------------------------------------1---1---1-1-1-- * a.60.7 5' to 3' exonuclease, C-terminal subdomain
[ 550] 53224999IEFHIH8F8453322794458763-----------1--26--2---73389122213-33 4441111111111121133-32111132233111221111124112131111111111111211111---1122211121131--1--1111--------111111141--------------232456612B122223433411F6455662222445322562844332232222222221224422-B454444465644666857555644444626321222222352111111111111112111141112213212331135121121-11-----12-521--11111111-------------1---------67377454555333373432322424233326966D4BA535833441---2-8232--1-122112-1136547----------1-21--132-33416236344653162412123323112116666666624431121------------3155233331441----12134-111135456554111155221-11213744242-3312432212422353171112112332332932411131312311412211462442A13222111151----------------------1-87122221121111111112211112231111--26135------11231224331423243-3235542434332224222333613433213212122234332232431121-311111111211--5111111111132111222111-33322311----------2211112112121131213---------1---1-----11---22524223333122-11-441121--------51-----1-111111111111-111111------1---1111 -----------------------1-1------------------------1-1----------------1-----------------------------------------121--2-1--1113311136111-311-1311131111111-311121--------------------------2--11-----2--- ---------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.129.1 AbrB/MazE/MraZ-like
[ 551] 11-11123323333331121111111111112111111111112123121222111111111111-22 2232422322222323333-342229333332877732344654322222224323231123424245542222222211114111111111-1------1--11221---------------------------333332112411141111222111111111211221111111111112111121132111111-111111111221111111122211211111122111111111111111211111111221111111112211111111111111111111111111111111111111111111111111111131-11111111112-1111111111--11113115362133411-11--111333122222134551114224133333333335-45244443396266656656668746111344555564611111111411131341111111111-------------------3112311111145545422222443533332345211311111233111124214112141342111111111112211211111-11111-11111111111112211111111111111111111111111111221111211113433322222222223232---1123------12111112221211122-2222211222212222221222111111111111111111111422122222111111111111111-111111222211353111111111-111112222222111418888988798988445511111111131112111111211122333334441111111-111111------------------------------------221221211111-- 1111221-411-12222333563545343333333342322333332224433543344444211111-11111111-1111111111136223343222222353--5235A33541221231212428H4-4252222312321212-322214334133652165253562114416---35C5AA27411212-3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.15.9 Glutamine synthetase, N-terminal domain
[ 552] 22---16333333337-12-2---62252123---------------1---1-11------1----11 1452211111111131111-151121111112322336342452111111111111111122413222223--------1---22421111--1--211-434262233--------------33-1111--2--23323---25132211211222122233213534211111111211212133---23222222323222222223332332225543221112114221112111111111111111--1--1-2----------1-1------------1------------------------------------------------1----11-----11--2---1------1-----1----2-423351111134765643333443344344344413584393556314443856665983222243555553452222222233322431331223231111111111111111-314111223-155375333343233366487777574575768227664345432636243445434211111113647433-1---11-1-221-514-1222-335333-12111111111111111111131-242222143232333333333323333324532311-53-311111121111111111111111-1111111111111111111111211111111111111111111111----111111111111111112211111121133311---------------11111111113277775657544456222-1111111111115222224333233222222221111222-333233------------------------111---1---------------45-1 -2---32-11-12-42-3-311-2-13113223333-----1212212-11-1-2136-11-71321---222-218-522-11111-2-31-123322223--15-12-9311214512-1229A1726T4-53C21133-3431111-2--1231-4--B-2261612*-19-121-711-2-6--736124223-4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.24.1 Cytochrome c oxidase subunit I-like
[ 553] ---1--1111111111-1-1-1131--112111121222233122212113321-------121--22 332121-233311122211-13--2311111132222434121111--1112233112--111-1-132211111111--1-111212--111---2---2-1114111---------------2312122212211-11111315142113112211131133213323111111112111211111--211--1-1111-111111113211111-11111111111113-11111111111111-111111111111-1-111122-1-1111111111----11---------------------------111----11-131111111-1---22------2--1111122411---111212---1131111-----123221-12211211111111111-22121121114-1111111111111111212212112241111111122211212-----------------------------422111111-12222222111122231111112222222-122152-1123222123223231311111111-1242-3231232122112-223232234222312111--1-----1----------2122233122122212131222222222211111112----112------11112111111111111-1111111111111111111111111131111111111111111111111111-111111111111-------------43214------------11-22232131111222222223323223222---------41112122221222211111111111111113-331122---------------------------------222-11--1-11111-- 1---546-----12243534333344411111111122222221114334454433322444663232223144443245233443233242343A2231232455-5R6P7988A55235333572A4X*81O9D2433A455343434421B465465AI3B8B3223588H528A5*43465D9CV5748685889 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.44.1 Ammonium transporter
[ 554] 1----211------1-----------------212-1------1-----11112-1----1-----2- 3423422212222141133-321122323321222214463235312231224441222243423346353222222221113223232223241121-33333434332222222222222224333333334342233---333333333333322223333344344222111222121112332222222222222222222222222222222332222222222223223232222222222222222322322222332222222223222222232322222222222222222222222222222222222234222222222222223233322222322222323321223222222222212-222312112222232222222222222222222-221222222321311233233322122211122322222222222222222231222-1------222122221222222111113412243332222233233332243333333222333222442232332332422333333333343333333333333331112121111223222222334334232121111111112111112112222223334333233333333332333333233332-2323212-22233333333333333333-33333333333333333333333333433323333333333233333333332333333333333122211111222332421333333333333333333333333332333332323332333333232233323333333333333333322322222322211523344332223222221--------------------------23133222222223 -------------111---1---2131------11--------11221-1---111--------1----1--1-2----------------1--12-1--1------1311------------------1----------------------------2111-211---13--31---13-----2--1--7--2---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.5.1 MurCD N-terminal domain
[ 555] 11213112111111112111-1121221-3-53231112111232-3432211211111112221-11 -27--------21---111-1-112-1111121---12---121---11---2-------2-----211--1111111--1--1-111---1-----11433331--211111111--11111----11---1--32322---2-12-23311-22--12-121--22211111111-1111-----2-2--1------1----------1111--1----3-123333211143333323344433333332223223333322332113322232233323333332222222222133333333333333332223333-12211111111-1---33121---1-11--1122111--1-1----1-1--1111111111111111---------11-1----2-11-111-1122112221211112112-211111211123---------111-2-11111111111111111111111111-1--111-1121113223332222222232222222222233311111122113332212211--1512232222---33-412-1-1-11111112-21-121-534552--------------------------1--1116113-512111112112222-2-1221111---111111123211212222222222-222232222222222222232313311222212222222222212221122--2222222222221112444443333112-2---1111---1-111------12213-11112342222422322------1--343333233233333221121122211112111----1133333333--21--1--1--------------------1----------2 3322432-633355331213553777733122234123332334442333344D5332253435523313435345425434443421317212123333342454166D79856697342554C63B3Dn5177D5144A254545325514B2644647G33341631636562341812222E69I2A44563355 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * d.179.1 Substrate-binding domain of HMG-CoA reductase
[ 556] ------------------------------------------------1------------------- 1112222222222222222-22222222222223332222211122222222222222222222223232211112222222122112323222222-2222222222223333332222222222222222222111111111111111111111211111111122211111111111112221111212222222222222222222222222222222222222222122222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211122222222222212222222221112331111111121111111122212222222222222222222222222222222222-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211112212113212111211122111112112223222222222222222222222222222322222222222222222222222222-2222222222222222222222222-22-22222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222223222222222222222222222222222222222222222222222222222222222221111112222222222222222-222222222222222322211122121111122 32--222-5111123--1-----------1-------------------1-11---2---1-------------------------222352-2123231--3214-266425222-2241332A3294EY4-C5612223-2312221242222--2322123232222232223463j34443B474-582442133 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
[ 557] 11111111111111111111111111111112111111111111111111111211111111111111 ------------------------------------------1--1------------------1-----------------------------------------1-1------------------------------1-------------------------1--------------------------1111111111111112221112111111--111-111121-----------------1-13-------------------------1111---1--------------------------111---1-1--12--------------21----1--11-----11--------------------------------1------1--------------------1-1--1---1-111-------------------------------------------------------------------------1----1---------------------1------1-1---1-----1--------------------------------------------1---1--------------1----------------------------------------------------------------------------------------------------11-----------------------------------------------1111---------1----------------1--------1----------11------------------------------1------------------------------------------------------------------1- 2212583-G682124548644455367554444444565675543545567565447666674322321234232443432223239663654454544345378A1484OCHADFLFIEDFHAlXJXIu*V4WPaKGGERGGNICJLIAQDClFJAAC766D8876L67CAGB53653O643458HAF7G7738CCD6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.160.1 PAP/OAS1 substrate-binding domain
[ 558] -------------------------------------------------------------------- ------11111-1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----7641----12611532444331422112211122111222222245543E27432222123111-32132322-2244432143446213332212222EAC1511GacZdVPFGDBKQDucAcJ**X-WUcCHDEZCMXLBKGFENFBgIOLHOCFDB7AD6LB9FAICA1553B--245Lhf*4*D4637461 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.37.1 A DNA-binding domain in eukaryotic transcription factors
[ 559] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----333-21--458656766667557666656777677776765665667776576567776453453456545564665555566667C656575556457BAB-712DSVQgRdFFCCGIDxtDfC**M7eOkEGDEXEHTEAGFFAQEA*HNHFF563965547A68BE442121222211BJOV7Q71-12312 -------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------- * a.7.8 GAT-like domain
[ 560] --1---1-7224--27--------24431193------------------2KE-----1-1-12---- 344------------1-----2--1------11-----21--38-------------2------1-12--2----2-----3-----1--------8---6-1--B12----------------3-86K72-6-6F2244---1-55F-C8DH1--------1-C-4B25-5-----6-----19----1--------51-----11248-------831-23-------3----1--1-22---22-432-1------A--1--JJ---3-----------22--212-----1--1----------1----44322222-4D11------2--3-A422-3-E-82-3-2--443E146-22--112-23--A111---------231---4112-----------------1---4--------4------------1------2--------1------1-------------C--7--B---------------122111111111111111221211111111111-11111112113111111421--3-12123311--9--4I351331-2-----463116JA69847-8-1-----------4-71-----5-1-A---1-32A31797A2633A-93662-H8444L--371-7------11--4--132K121311-111-283334327111111-111-28F7--811--4-1S7S811--32111--3*rm5***uF2E-----2-221512114-4111122-12-2324--------11-2-1-2231-42233212332----4-------S47457-----5511312111------2---111----1--1------------------------------2-3-313-2-421 ------1----------1-1-1-------1-11-----------11----------------1----------1---1--1---------------------------2111--------1---24-1-151-1111-111--1-1----2--1--11---3--------2----1------------1--1--1--1- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.57 Transposase IS200-like
[ 561] --2---------------222211--1------------------------1-1-----1-1---111 --1--1111111-2111----1--11-----121112221---1--------1-----11---111-----1---11111112222-2--1-2---132212-111111-------1112222222112121-2211111212214454443343334122435413434422332223323-111111-22-3232333333333331122223332221221333333223222222122222224334324222222343111122331111233222222222322222222222222222222222232222222232223-2222211-2122--1222112231221211322152312222122111-221222321233321-1324233333334333-111112122612333244465444111-22111211423111111112112111-----1111--2221223222322232312111212122233332333322222422222222222121221221211221113-22211112222221212222321221111--11---11221222211---1-2212-222222212122222221-12111---21-1111211111113211121111112-112-11122221222-111121112111-1111111111111111112222111111111--11--11111112211122122333333333332-11221211311211111111-2111121111221211212111111111331224122122222222221111111111--111322223233433332232222211222132122-121222-11122-322121222211112111-11-12212 881155317-1-2122321322311124433445342323323233323523321-32323321112211121322112122221132223131-23221412325-3B2433436632-2362522458K6-25722735436414322422844332353-4633644114437334V3223385452721252532 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.34.4 Electron transport accessory proteins
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c.121.1 Ribose/Galactose isomerase RpiB/AlsB
[ 563] ---------------------------1---------------------------------------- 1122222344321222222-22222222222232222322222222322222222222112212232322211111111111311211111211111112222232222111111111-1111122222222222222321114144453333333333333343433333333333323332221111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111-111111111111111111111111322222232222113321211-21111111111111111111111111222222222222233333233333222222222221222222233322333333333333222221222232222222222223222222211-111111111111111111111111111222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211111112122222322211222222222222222222222222222222222222222222222222222222112222211111122221222222222122-22222222222222222222222222222222222222222222222222221222222222222112211111222222222111111111111111222222222222222222222222223221111111112222222222222222222222223222221214433331111111121111111-111111111111111111111111111112212 32--112-722-2221222222212122222222221212-222222222222222222222122222-222232221222222223332322122--11132335-2F143535333312133542616G3-648332332341231226225453331--22232222542125442H21233B8792A37922227 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.45.1 ClpS-like
[ 564] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------1----------------------------------------------------------------------------------1FVRMwNbWLHPTTW*sOyR**m9vZ*JNPLaPasfEZPJF*EIwNkMWa7Jr-7999---p--6--------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.23.1 TB module/8-cys domain
[ 565] --1---11111111111-22222-3112-11111---------21-111-231-1111211---2--3 212112-1111111211----1--31-----12111431212124123111232212-11224211122111111111-21-211111111---22---1-11112------------------12-22112221111111-111332111111111112111-11122-------------112112212222222224212222222122122223432242333333463333333333333333332211212211111331133-1-1212221111111311222222222221111-1111111121-222111111143222222222211--2-2112111--1--11-211------111111211114-----3142442334624-111-111113-2322215111111111222121111211-4-22-22--1111111112111122111111111-----------------1111-22411-11--3222222111122222222121232322111311-12222121122121-11-------1-211122211--1-221113--1-111311222232111112-11111--1-------2--1233222311-23131111123111131112321---2---------22112222222222222-2222122222222222222222221-1222222222222222242222222--222222222222---211111222212111---1121--------2222221-111-2223-122-11233--1---------2---1---1-2111121223222221111--11112222------------------------------------111111-111111- 1111332-312122332322332323322121211111111112124223232412223343322111121222222222122224211421223422313226341446G9E9CBA6649788ED6C7JnB-E9I6684G67A458797A76E6AAAA6A597554E575797214211-111362382843153252 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.52.9 Cation efflux protein cytoplasmic domain-like
[ 566] 11323251222222214133333321121511434446664464234511567754353852123-11 33513-2-------13122-21--44212221333313323343-1--1-----------22322224321--------3322555532221111-1---211122311--------------1332433124436556555532244333211221111112212332311111111111111111111-1-1111111111111111-----111111----------1--11-------111-----------------------------------------------------------------------------2--1211111111-13-------1-1--2--5566211-2-42--221--36-111111111746572114963611111111111-11111111111111112222222245111123444411122222222533127251111111111111111111111111111111113-11111111111111111115222212144128511211341111427121153121111111111113357134-62336545561847677818556514184333222222222222222233746553412------111111-11111112111211--241311111132334215554544455-5455544555545555555222311136666666666646465255564451-31111111111111111111122234-11-111121---------11111111114-1121111111211-2112111111112--------------12222222221111116-222222------------------------------------121111-11-4621 ------3--1-1421111111121112112111111211111132233112122112211111111---1-13111-----11121--112111291112112112-22252432432131232D72428O4-4552212322222332242131314323232282545213351111----112335125112312- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.18.1 HydB/Nqo4-like
[ 567] 1111122111111111223433221--11211111243111113223961223122123221114--1 223--122111111-1111-13--24111111323212221232-221-2211121-1----111232211----111-211112321-----1------1-112-111---------------221222--23222122222223333432212222211133113331-1-1---1-11-11111221-11111112---1-111-131111-1111115-1111111---1111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111--2211111112-21----1111-11---11222--2-211211212--123111311111244353215522611111111111-64653335-21-111132223422231231434333221--------2--11-22111-1111-1---------------1111-1133-3221322232222222222422221223334642233333422264442322412122---------1-2313122213122222122212222122221222111111111111211111111221211331322112-42333311233332423333---1213------34222423964333322-4333338354544333332454211122232222332323223234222121-311111111111---211111333322222222222--------111111-42433-433311111111111112--------11111222221121173422222221111--4111111111--1-1-1---------------------------121-111111231- 2-12--1-4121--2321221-32112111111111-1111111111-222--1-1211122-----------1----------------3-222---1121111---46B3232311444445953647I5-6444335434434444244444544522134322B241-11112111---119*c*1fG214131- ------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------ * d.58.10 Acylphosphatase/BLUF domain-like
[ 568] 1---------------1-----1-1--1-11-1--------1---------1----------1----- --2-5------------------------------------1-1--1---1-111-----1--11-1221--------------1---3342--23-------1311-4------------------111--2--122-21111-2151--3--------------5386---------------------------------11-1-----1-----1-----------12--------------------2--1--1--------------------------------1--------------------------------------1111-1-1---------1----1---1------------1---11122------15IJD25153678------------11911B11-7--21127427851114-----23-22--------------1-1-----------------------------------1--1--------------1111-------21------1-----1--21111--8---1------------113---52-----5-----123----111-114-1--------1---1----------1--------11------1------1------------1--1------2---11--------------------------------------1-1-------------------------11111111111---------------3-----------------111-11--1-----1-1---1-1-1---1-----------232-------11211111121111111--1-22------2----------------------------------------111-1-- ---131--1-1--1-132263315342-11--------------112333559634242433-14-11--212-1------11-221-135336361311-11221-363*ISJHUVCCEDDGAKPDdA**Y-hPSEFDFODEFFDGGFFJDCgFKGJFKOLFjIR7AIB927E8--2-3--1-1-1221---1-1--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.17.1 Caspase-like
[ 569] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11---1-----21------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------- ------2-------------------------------------------------------------------------------------------------------oTkZacaMAJKGWJoVGTE**W-XRdGIGFPHJiSBLOOTSJEdNLKeNBE6GzgrBx7Dg**N--11-----2--------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.8.1 BPTI-like
[ 570] 11111-21111111112123433-32223342-21111131211132311122311111111111-21 111-11-----11-11111-11111211111111112111-21-1--11----1----11--1-111122-1222111----1--1112111122211-1221211111-------111111121121111112121132---212232221211212111--12-2321111-111-2---111--11212111111111111111212121111111111111111111112222222222222211111121-11-111111111111111-1112222333111222222222222222122222222133222333111111111111111111111111111--11111211-11111211211--111----------1-1-11-11111-----------1-------211-1---111-111-----3----------1------------------------11--1-11111111111------1---211111231111111111-111111116-13111111111-11-1111---1--11---1----------11--3-11222211112121-2111-------1-----11111--------------1111---2-------1111-1-1111-1--1--1-1-11211-111--11---1111111111-1111111111111111111---11-11----------------1-11---1-1111111111111--1-1111112121---11111111111111111111111-111---1----1---------1----1---1-111------111111--1-----------11222322---1--1-111-------------1-1-------------1-1-1--111 34127541E55644833456656556577355575756564354545554434423323333223454135315246145566641555554364966543954341554A7A67DB7966776DD4K8X*C1HAO7748B489B75567B63C5D9974B768462647I58252244V75525899B4981245453 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * a.289.1 Sec63 N-terminal domain-like
[ 571] --2----1----4782-111111-----1-11------1-31111----2--1---11112--21--- -55122-12261-552-1---5--7-11-1-135455ACD-5EA2123-432769222--232--11251-1---3---113------4324541-2--11---642----------------1---1---21-4-11--379313-11221--11-----142-1324112--11-31--1211-----342232332B9C58J26D21421345726242215--14185444443111333224-D565612-421226--21121122311-21-2-1132--111141111-1-11--3-114311--11---4-1--C252-1-4321422D8EC525212A3111C9283C26113113123-----25112111-1-3844BA22211322222221229-A9C77D9A5A3-833371C8-2-51B122A195621311GGGGGGGGD966-914------------1-11--31-----2-43--3B-2----23111311----11-944-255-762419--3332-642271--5-2A-2-1-1-------582415-1A-2-24-811-2-531531--D251113111------1--2-----1-5-11-111--3-2811---3-6368-42211425114-----2----------212223343132-341-4233-412214124424426621-22-13--25-14-2633-622-312121--2221212211---A--1--111112-4--------12----2--3-3212--3222133-1-2211--525711---------31-21312334---1-6161----2121--8---------------1-2----------1--------------1-2-2-----6--- -----3--1-1-----------------------------------------2---------1----------1----------------11-1---------------------1------------------------2-------------------------1---C-----------------2---------- ----------------------------11------------------------------------------------1-----------------------------------------------1-------1-------------1--1----------------------- * c.53.1 Resolvase-like
[ 572] ------1----------2--1------------1---------1--23--------2-1-1---1--- 132-211111112121111-11112-11111111111111122221212121121111--11242123331----1--212-21-11144551311---11122211232222222222333312221212222433344---222432322-111--1---121-1211------------12111222111111111111211111211111111121-112111121111111111111221111119111-2112-111111111111---1111111111111111111111111111111111111113111111121113111111121222111544213221432333232211242212311122---11------2--1-------11111111111---1--1--1212111111211111----11---------11111111-----212--------------------------------1------------1---------1111--------------22111111211--31---1--------11211114351121121111153442332311113334---1---1------------11111--121211123-2------1------------1--1-1211111111111111111111111-1111111111111111112222221111111111111111111211111111-11111111111111112222211111211-111111111111111--1----1----11------------------------1111111111211111111111111131211211111112222222232211111---1111111111111211133333242222231 5656323-9131222446224224345223222224423222232233333223223232232555552464644442544445442223724442444534345534526GJEKB57574767796E9Q*8-ICC7558C87A13773265568B66448L95423624557323443O22244IDIK3EB3211225 ---------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------- * c.89.1 Phosphofructokinase
[ 573] -----------------------2-----------------------2--1-1--------------- ------------------------------------------------1------------------11---111------1--------21-------------1---------------------1-1------22-------1-------------------------------------------------------1--11--1------1-------------------------------------------------11----------------------------------------------------------1---------------------------------1------------2-------------------11--1--------------1---------------1---------------------------------------------------------------1---1-----------------------------------1---------------------1-----------1-------------------------------------1----------1-----------------------------------------------------------------------------------------------------------------------------------------------------12-1--------------------------------------------------------------1-----11--------------------------------------------------------------------------1-- 111144A-511Q11323444444433544354533324445335543445454444464333221111-21221111-1111112112124134143232222142-812KNZLMWNIFIIMLHhdFjH**Y1hOiIJHJYGGSJFHJHGSJFXFKKFH7AK9LIH6HAHE7876-1-1U2322-89FL3A6339HHC3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.65.1 Annexin
[ 574] -------------------------------------------------1------------------ ---------------------------------------------------------------------1--------------------------------------------------------------1---------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------11-------------------1-----------------------------------------1------------------------1------------------------------------------------------------------11---------------4---2---------------------------2-------2---------------------------------------------------------1-4----12--41-4---------------------------------------------------------------------------------------------------------------2-2-----------------------------------------------------------1--1---------------------2----------------1---------------------------------------- -----18----------------------------------------------------------------------------------------------------1--nRcomzSPKQLFHIcgUaT**c5mJrLQGOWUGUDIIJMSSLLmQROR*GIUWbeIENPEdEAS5-----------------1------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.120.1 Tp47 lipoprotein, N-terminal domain
[ 575] -----1-------1--11-----132232222434222222222225223787411-2222-221231 121-422422232231211-12111111111121113222322252221111332231221224323676211111112122411111111112111--1211112111---------------11123111222322111112344583334555233232334556631221222211224441111-24333333333333333344222333276413111111115211111111111111-11111111111111111111112111111111111111111111111111111111111111111211111111124343222222212232331222214113128466867444373332-111-222112222246954K535776522232122222-76966979262125423433223453131341454441111111111133-218411111111111111111111111111111-222311211257737532111559823221144C343211221111113111211112111111111111124A31111111111211111121111212111121131111111111111222222211111111212141131114214111211212112111-1511111-11111111111111111111-1111111111111111111111111111111111111111111111111111-11111111111111111111111111111311111111111111111111112211111112111111111111113122131111111111111111111111111111111111111111111111111-1---11---1--------1-------1211111111-3-1 --11--2----3111-11-1111-1-11-1111---1------111-211----111---1-1-------1---------------------1----------11---111885B453221432551938W4252A241332332-33215225226461-1211118122142-2364N344523223-2-23-1--1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.41.1 PRC-barrel domain
[ 576] -----1-------------------------------------11111-------------1----1- 111----1---1-111111-11112-1111121111-111-1111-1-1111111--1--11--2-1-1-1---------------------------------1-1--------------------------1---------1-11-------------------113-------------121---------------------------------------------11-----------------------------------1-------------------------------------------------------1-------------1-111------------------1-----------1-2-----------111-1----------------1-------1---1----1111111------1-------------------1---------------------------------------------------1----------------------------1----1-------------------------------------11-----------1111-221--------------------------------1------11111--1111-1--111----1---------------------------------------------------------------------------------------------11-----------2--------------1--------------------1------------------------------------------------------------------------------------------------------------ ----11--------1-11--1------111122112-111-11-1----23212---21111----------------------------211---111--------21-*d**Z*WIFGJJHIzlF*O**a3rR*FOLEYGJNP5LMDCUDD*IDBBH96--A351--1---51---------12---2-1----1-1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.321.1 STIV B116-like
[ 577] --------1111111---1------------------------------------------------- 5NG--------------------------------------------------------------------------------2321378D9-523---2545344857--------------122232222364-----------22222133--------31151111-------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------2-54-6352-111176765785B84BC22222222223-12211-2334513332222123324364911222222217777777763353252111-------1111111-111-1111-1115653333333345563744443353444432B69454323433665335335335877756441111111334449E4232323623663133344555667A4OF452243243222124221222265-22BB64244A937526676665656444689437--13334------32252322343243322-222423523433322222233388446222221222222222254522223215333333333332228-111111115352333311212222322244544663427B6666688A4343459A91--1-----234543333345344GJ9AAA999B66661141884444-----------------------------------------1-1--9K25 ---------------------------------------------------------------------------------11----------1------------------1---------------------------------------------1----1-------1----------------3-----3---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.212.1 TolA/TonB C-terminal domain
[ 578] 11--------------1----------------------------111----------------1-11 2232221222232332222-22222322222222222433222322112222322222112322333333111111112112221111211111112--121313213311111112222222122222222132111111112211121112222222222112211122422122522223221111112233333435335333532332333324322222222232122222222222222222322222222222222222222111111111111111122111111111111111111111111211111111111222222223322212222232222111111122222312211111112212211211111123232222222222222222221-33633426231122242243224411111112222212211111111111122211112222211222222222222222222211111133422333333222223233122222323334423222231111212113131111411111111122113321112111111111333221222222225111211111112411111111121122112212132111221111111112111111321-1221111111111222222222222222-222222222222222222222222352222222222222222122222222222222222222221141222222332111121111111111111112222221221123333244322222123312212122211111111111111131222223211111111122112222222222211----1-111-111---11111111111111111112312 22--1---2----21-1------111-11--1--------------11--23-311-------11---111111-111-111111-1111-111111112-1211-2-11E444441554534476294Mo6-B6B333182564345335227434234432523-6322135512217211124223-321242322 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.46.1 FMT C-terminal domain-like
[ 579] ----------------------------------1-------------------------------11 9OV3I--1111-1-C9844-49--6F434446CBCBD9JK18498G15333-767421--8AA2A6MHJH2---------1-1-------1--111---5C689O7H1E----------------1-112--22-23323---J45241221--1121112112111311-1-1---1-1--D6B221--3-BGFIFIKIL5JKKKIJADB939MJO244C853111111CK21111111111111111-221---------------11----11-1-1----1111-1-111------------------2-----------1----------1-----------2--91---12-------------1-D-95112-----233422221211111111111111-11211121334-511133334511-132323211111-2--------1---1-4-------------------------------2133--32123665441222255423333234333343-2332221223353423421--12--------113111-22---1-11-21--212---1--222224-11-----------3-------11--111321-323-221132221112222-2--2-1---1--1-------2---21------------------------------1111------111111111111112------------------------2----------14-1-------------1-------2---132212133331-112111---------11--1----------1113132111------1122--11--------1---------1----------------------------1-4 ----1-1-321-1114136232325422222332421111-111112224656644432322--2-----1-1-------------11223212233121-12211-14-41--1-31--112-41--2141-123--2-1-111--11111-211211111213---111-222113-13111-1--14111155242 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.213.1 DinB/YfiT-like putative metalloenzymes
[ 580] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------14331312-1-6213-22345544222121---21-1---211113212242-2-13-21211-------------------------------2-1--------1-------------------------------------------------------------------------1-------------------------------------------------------- ----------------------1------11-1--1-------------1------------------------------------------------------------21-6-1eR**rZsXPStQbO*5-rOBHzfmYX4*EhXEq*f**Y**e2*------------------1--------------------- -------------------------------------------------------------------------------------------------------------------------------------------------11---------------------------- * d.323.1 Phage tail protein-like
[ 581] ---------1-1--111--1----------1---2-1---1-1----1-1-1-----12-1-1----1 268-4--1111111-1-----1--2------12222-11--224--1--1-1-2------111-112122-----------------244-1--32---134121-42--------1------4211311-2-2--5622---4-1284341-1---12-2-13--3459-1-----1----11321-------------1--1----------------1-1-------11------------------------11----1----1------------------------------------------------------1----111--2--1--1111111------1---21--1--1----1----2143--1------112-1--1-122----------1-225224-3131-2211355435414-2221--2122-2122222222111312----1----------1----------------311-33211-1222211------12111111212121111221411--12-321132151--12222222-13114653514--22243116443232245757FJ42121-1----11--1------31--21-12112191124113111411311-113123--11121--------1---34434434323-43535343334342243231-1-2111----1-------1----2321122---22222222222---1-----21122122211121---1--112-2222112222211111112141-1111-2---------2--11-----332221-232332331-1-1135556664---2--2-12--------------1-1---------1-----2-1--323 1112585-B24223A35433622445433-27364412311251222224-387122663212213262451462342657464243533Q5584B3324227137536Ej5756497645483981A4Jk7-6AH9564967F517321544G6A8476B334942531522641166D42635A59G5A83955435 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.118.5 Bacterial muramidases
[ 582] ---------------------11-1--1----------------11---2111--------111--11 2222321222222223311-12112311111222223273111212111221312131221221224213211111112224212111222212222--111211222211111112211111222212222122333332223232423332322332232234233441311-11311112112212112111111111111111112221211122231212222221211111111111111111111212111111112211221113211111111111111111111111111111111111111111111111122111111111121221112222221111321-112113112122321112332224121112222322222223222122222221222232221112211111311111222111111111111222222222222212111122111111111111111111112122111221111111111111111111211111111222111-133231112432321223232212111111121231222121212121111122222111256648423222222222221211111112211133111111131313222222322223233223--12222--1---11231122222222222-2223222322222222222111216822122222222222222322112322-111111111111--12111111111221312221111222121112222212112233223222432222222222222212211423222222232211212112231111122122221111111111221-1--1-11211221112-221111122122222222311 -----13-753-2132322323332122222124332222312322523431321142242521233222322253324421112122415333232221131333126232543222135322263232E2-224223222222-22221113212351-125431431122333333e4445468962681241235 ----------------------------------------------------------------------------------------------------------1-------------------------------------------------------------------- * e.39.1 YebC-like
[ 583] 33231333333333332211211343333433323443333234234544433422211111--2-34 232-233333322222222-2111232222221444322222222123122212212111223222332233222222-1223123331111-1112--111112333222212221111111222322222232222223322212212222222211121222311121111111111112112222222222222222222222222222222222222222222222312222222222222212222222122132222222222222221111111111111111111111111111111111111111111111132143222222222221222111224122123444232223223333111311111222112223222222223222222222222-233223222321222322322233222332332222222333333332231222222111112111122221222222221111222222233333233333333333333333233333333333333343333332233333333333333333333322322312222322322421222212232413422322222212111111111222332211-1321-1111111111111111111111--22333--------------------------------------------------------------------------------------------133323222232212---------------222222233312222221112211221113333333332111111111111111121111111111121213333331111111121-----1-111-11111111111111122222222222221 11--11--1-1-11222222222221222123322232222222222122223223232233122222212222122122211111-2123223242221232222-1-2323112122111113-1313A2-423111221111-121-211211231-23-1111211---211122D222111114232121322- -------------------1---------------11--1------------------------------------------------------------------------------------------------------------------------1-------------- * a.182.1 GatB/YqeY motif
[ 584] ------------------------11111121111---1111111111-2111-------------11 1211111111111111111-131112111111111112111222111-1111111111--211111221221---1111112111111223211--2--1111-111124444444444444431121A11181111111111-13345338273311--2113325446---41--2-212111111111-1111111112111111111111111111211111111111122222222222222111111-1111111-11111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111--1111111112144211111325771112112411111111111-2222212-1111333A22221211251111112122-311111111121121813111---------1111111111111111122121113332522125244421125444424412221215111313114111221131343221111111211122-1111121-2-44453126111-21111161-11111212111112111111111111117111121111122221-122221211211--11111------22122231221111111-2111121111211111111111225524555555555555555113331134-877777177171--21111111111213212222111111-111111111111112144-41122111111321111111111121221111156111113232233211111-6211111111111211111111-1-111111111111111111111111111111311 21--321-91111-1334332335443333333342433352333322233353232334332-111---1---21--111111-21-133-32221-1112221211526123243221344372341IQ71339144143C833434333233235335724122311423322111823122765A5641355467 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.198.1 Type III secretory system chaperone-like
[ 585] -----------------------------------------------------1-------------- 2L61---------------------1------1---1---1------------1--------1--------------------43532--------------------------------------------------------1412144---221--11--13---1--------------------112--------------2--23331---1213121------23---------------------------------------1--1--------------------------------------1----111-12252222222212121111---21B--15311112521111111111---11622-111-141FDE97AA9BBD---------12-CBEADABG3732842495A98A698425312-1112-11111111111221-931-----------------------------1E88A24433556698465675444D4556357664989-2455542--52311-344232261-------111-25G87883EB-79877-CEB999B89HGAGLD4B-111-----------------113-11463489966725444375533344354446--14435------3222-422223224221-122222222211222222325454-12222-2222222222-162223321--322232222333---2-----334312F2-----11---1---1121111111124AAA8A8978B989A686622121122255558666667778943423223331111--C18855431121111121--------------------------2-1111111111-- -----------------1-------1--------------------------1---------------------------------------------------------1-----------------15B1-21---------------1------11---1----2----21-----------1--7---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.45.2 PilZ domain-like
[ 586] 11-----1--------1-11111-------11-------------------------1--1---1--- 2332422222212131123-22112321212223333343431-552322214442241133534344453233322222321112211112-111--------1----11111111111111-111111111-132222111311111111111111111111112222111111111111---11--2-223333333343333332111233332113-22222222322222222222222221222222242233232224422222233333333333332222222222222222222223222234322233331431333332342221622-24212122233214413221121222113211-2222-----1-3112-12212222222222222-11311613-31-333344443344321111121-11-122222222212221213-----------------------------11121234424546565344444445555535554455511444433334353322232223642222222111322211-212233222313332323224444211123322111111111111111-2111114521523223422222123222232332531-1111311-11143122432333222222-32222222123222222224342223344444444444444442223221211222222222222-1111211223221382333323121121-11222222122223366764543544443333111111111123362222255333222222222211111112111122--------21---1---1------------------1111111111-21- 11-1123-A521121--2-1--1----------1-1-------111--------1--11----11----1--21111-11111111212121-1141111--1222-243411221111111122121--1--111111-1112122-211-2111122--1--31--1----2-13124---3-3224-221332222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.116.1 YbaK/ProRS associated domain
[ 587] 11121111111111111111111111111111111111111111111211111111111111221111 2111111111111111111-1111121111112212111111121111111111111111111111211111111111111211111111111111111111111111111111111111111111111111111111111112121111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111112111111111111111112111111111112121121111111111111111-11111111111111121111111111111111112111122222222121111111111111111111111111111111111111121111111121111111111111111111112111111111111111111111121111111111111111111111111111111111111111211111111111111111111111222231211111111121111111111111111111111111111-1111111111121111112222222122-22222222222222222222221132122222222223323221211111211111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111221221111111111111111111111111111111111111111-111111111111111111111111111111121 45222251F542333434433333443664333333344443343333333344333253434444442444544555554344535555623545333333356514B2633353533333A3CH3849e6-65H4343B44891444233362332545435432C55735444775p3254598DC3A64353331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.24.1 Ribosomal protein L1
[ 588] 111-112111111111121111-1211112112-13333333313122-2221-11111111112--- 1321111-111111111-------12-----1----2152-11212-11111221111111111212142--1-----1-1-1-11-11112-1--2--1211111211111111111111111---------2-21111---1123222232233-1-1-1132213211---11111--1121111112111111111111212111----1112122211111111121111111111111111-----11111111111112221111111111111111111111111111111111111111111111111111111112211111111111-22111122-11111221123211222---1111111111--11-4412341132111211111111111-33313523311121131211112321---1111111211--------11111211---11-----11------------------11111121113111121111122222322221212243113321111111112112211111-11111111221121211111111111111-11112111111323211111111111-----------1113333211122-1212111111111111111211-1111111111122222222222222222-22222222222222222222222222322222222222222223222222221222222222222111111111111111111111111111111111----------6122222222322333221111112111122323333324233231111111111111121332222111111111-11-1-1-1-111--11111--11----2111222221112 22--671-A21233335522133687511133352251121122114425452823921311112112112111122-22122231112131513521111114481253247344422232323B172Ed5-53C221242323-2312211312123245422238235362348B8*32366IBKI4BC879B996 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.49.1 PK C-terminal domain-like
[ 589] 1111111111111111-11111111111111111111111112111111111111211111111--12 1222621223211324122-2222322232334222433417152112132143211311431171437311---1--211131121111111111---1111141112---------------112111212111222211121112111422113323112111114212111112212211211--121122222233233322211221133323231121111112212221222222222211111111111111111211111111111111111111111111111111111111111111111111122111111123111111121261111211-12111111143112121121111121111222111112111441143121111111111113-1111131241111222131241231123-1142322335111111112113311311111-11---------1-----------11341112313577765666767734787626566341122111212111223421121111111111121122121114212121112221111111212133267111111111111111111111111111114322121221121111121111122111211-11111------11312121111111111-1111111111111111111112122221111--1----111113111111111111111111111-1111111111111123122221111111111111111111112122242431312111132111111111111122222233122113434454311111121111111111111111------------------1----1---21111121111111 23116A6-544-2112142824323252233222312122111213633428624332233311122211112231211122211111143216331213322221-3D383135242221334631519E3-42722-2311121111211133111224324235322213411436K3222457877644255654 ----------------------------------------------------------------------------------------------------------------------1---------------------------------------------------1---- * c.72.3 CoaB-like
[ 590] ------------------------3113-1-1------211-11--12--522--------------2 --3-1---------1--11-1---51111111----12--1-1-4-1--1112-------22---222121---------1-1--211-1-----------------21-------------------1--1-2-23344---7324344411133------25313461------------111------31222225253422552153231232241E1451-----B91--------------1-----------1---------------------1-----------------------------------------6739222-12253731552---933--5--5234461161111--2---114-----------11--1-1--23--------------2-11-1-2--2--122221222111-11--4-44211---------22--3-1-----------------------------1--1--211115334374122166262222225564244--4342131232181-232--217A11-----3-147825412243-842161BBDG6BB47225-25-32111-1111-2---------26411--F6246462543DIEFEA77CAAF8878F9A----31C------42163211222112211-211111111122111111-212441-1232222222221212221111111--233333223333--11---------1-E28---111-1111-------------123JHCHFGEGGDBABEIGF---------4A99GGFFFFBC7GF--23432323------85AA44651--d-EI192------------------------------4------1-- 1---1---1-----1---11-------------2-1-------------1-------------1----1-----111--1---------12--12------1--1----411----111--------1-1411111--1---111----12--1-3-1211---11---2--231--------1-2--2-1---1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.154.1 Variable surface antigen VlsE
[ 591] -----------------------11------------------------1--1--------------- -2112---------31111-13--12111111644413--2--151-45---221114----3-1132541----------42----15212-311---121133-2-2------------------11-1-22-12212---5-5322223113322222323244464232221221222-----113-224444463424347732111224472222254211221642--------------11-112-1-1------22-----1-21211111111112112222222222211113112112222111111111-542233333332425411-1113-111122-111-411-----11---13-14223-----466677643555544554444555-664565545721666668568755661215444356334------------1433------------1---122---22------32212-11--2332322333322213333243622111--1-131-11141-133231---6--1--2-211-222323-2-1622211133-2-3131---1-8A141212--1-----2--------1-11113322-3111222222222422222233225--1-1--------43333343332332243-3336332334324333332322333244444444555544444644222332-544464444477--33-----22224-2213333532453433333333343111212221-214123431111111111111-5435222223353443334334451111--812211111111111122--------------------------2-----------3- ----31--1-1-------1--------1------23-1-----11-1--1---1-11-111-------------------1----1----1---11---------11--2A566674433223334143AN5-235-33231454-33213133362344662352122152-2----2--1---2131-----1---- -------------------1-----------------1-----------1---111----------------------1----------1--1---------------------1------1-------------------------1------------1-----1-------- * d.65.1 Hedgehog/DD-peptidase
[ 592] 1112-1221111112212332221111-11111111111111111122111112111111111121-1 1221311111111111111-1111111111111111111111111113111111111111121221221111111111232221122233332333222222222222211111111111111211111111111211222222311211111111111111111111111111111111113221122123222222222222222243332222234332222332224222222222222222222222224222231112233333232213333333333422333333333333333333333333433222333322332333344424225332232222223222233222222222232122222111111111111111111111111111111111-1111111112112111122223111111111111111111111111111111211111111111111111111111111111111111111111122222222222222222222222222222222322111211121222222232111112122222112122111111111122222222221222222-----111111--------------223322222222222222222222222222222-2222222122223222322221222222-22222222222222222223232222233233333332333332222221221222222222222222222222222222322222322222222222222222211122333322222222222222222222222222222222222222222222222222222131211111111112112212121--1--111-----111----21121222221113 1111111-31111111222111122311111111111111--1111111211211111111111111111111111111111111311113121111111211111111244332282221242262123E212232222522211221132362222P13523211123322141121911111212212111-1111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.153.1 PheT/TilS domain
[ 593] 3314331122222222426455652122-213223552223222221332222667756671113222 ---1-----------11-------------------1---1111--------1--------1---1----1-------21221-----1111-111---11111111-----------------11--1--1-11111-----21121-111--11-1--1-11-1--111111--11-11----33---11111111111111111111111111111111--111111111111111111111111111111111111111111111111---1-11111111111111111111111111111111111111111111111111---------1111111111-111111--------21-111211-1-----------------------------------1--------1------------1--------------------------1------------------------------------------11--111111--111122111111111111-111111111111121111-1212111-1111111---22111111-11-------1121112212222212-2--------------------1--1--222122221222323222222232222322--1-2-----11122322222222221222-2222222222222222222222222222222222222222222222222322-222222222222211111111111111222222222221222222111-111111223333322233333322211111111122221222222222222111111111111--1---11----------111114-1-111-111---11111111111-112-211-1-- 221-633-A42112232214322321222422332222323333445246444644342334221113212223132-4222222232112224573333--163712N4987776BAACBB8B786A7Ly8-A6B5D6B97799669D976A5C67462A553427422634521443R34123EDLR23C4362546 ---------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------1--- * d.308.1 THUMP domain-like
[ 594] --1---1-111111111--2----1-----1---1------------1-------------------1 1-3-----------11111-11---111111------------1--------1----2---1--3-1--1----------11--------1--1---------12--1--------111---1-----1---1------------112211111--------111-1111-------------------1----------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------1---------11----1----1-1-----11----------------------2---1----------------------------------1---1------------------------------------1---------1-1--------------1------------1------1------11------1-----11-----2--1-1---111-------------------1----------1----------1----1---1-1---------1------------------1---------1------1--------------------------------------------------------------------------------------------------------------------1------1----------------------------------------1-----------------------------1------------------------------------- -1--686-1-41554GCEDEBDFHFFFCCBABAA889999A89BB9FFHFGILNDEGGFIFH9548653459447655565444447549A6C98A34564H377B-4C5CDCACAF87797B8HF7J9T*A1IAS8775D88EA58766F97I8D78C38677688F76MC8851223U2224656A7F583466979 -----------------11------------------------------------------------------------------------------------------------------------------------------------------------------------ * a.102.2 Seven-hairpin glycosidases
[ 595] -----212111111121------------------11111111-------1-1-11111111------ -------------------------------------------1-1--------------33-----2---------------11112------------1--1--------------------1--------1---------1--------11221-1111---------11----1--1---1--11-111222223121223332221111331111-111------11111111111111111---1------------------------111--------------------------------------------1---11111--1-1---11-----11-----21111211--1112111---1-----------------------2-12112221----1--1-----------1-------1----1--------11111111-1111-----------------------------------1------------------------------------------------1---------1--------------1-----------------------1-------------1----1-1--11-----1-11----1-----11111111111111111111---------------111-----1-1-1---------1----11------------1-----------------1--------1---------------------------------------------------------1122---1------1-----------------1-11-----------------------1111-1-------------1----------111--1------1111111222---- 11--957-733C111222111212121211212111111111111122112113331121112111111111112-2-1111111111122121121121111322-26M*HKGKJSCEC9HJEfa6UA**T8VFs9JEDUAGQD8JC8CR84mGIEFF9IqCJG96G84HBH991142R-22-174D81532222323 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.156.1 S-adenosylmethionine decarboxylase
[ 596] -----------------------1-----1----1----1--1--1-1--111-------------1- 11-1------------------------------------12111-11-------1----2----11---1-222----1111111111111-1---111--121-221--------1-------11-1-11111----------112-22-221--1-1--2-112121-----1-----1-1-1111---111---1------11---11-1---11-1--1--------------------------1111111111-1---1111-----11111111---1--11111111111------------1111111-11--1111-------1-111--1---111-1111----1--1-1-2--111------11111111---1-------------------1---------1--1-1111121-111---------------11111111-----1--22-1---------1-1-------------1-112-1----1111111----11-1-------1----1--1--311----11-----11-1-11121111--11--------1-------------------1--1-----1-111111-1-1---1-1----------1--2-------1-----------------111----111-----------------------------------------------------------------------111111111111----111-1-----1--------1---------11111-111---11-1---1------------------------------1-------------------11111111111111-1111-1----1-1------1---11--1-1---------2-- 33558551E5664346532455546455554446464555455444545876665555655587463534675479949964444566525456267563533649-6E9I8IDGFAB7879A9FE8K7l*D1BEI9876CBAB968778B44H895CD69G6DC99P53A5A774683*24565HEEM5BB6798C74 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------2---- * a.8.4 Heat shock protein 70kD (HSP70), C-terminal subdomain
[ 597] 332133222222222223232321344423341111-1111111-11112222112221332221122 1122222222232252244-424454444443233334743425223222222233222222535234442222233322223-----22222222222322222223222222222222222211-------11233341112232232222233222221233223222222222222222422211-222333332223223222222222222222232232222233222222222222222222222--22223-22333322222222222222222233322222222222222222222222233322233321--22----111-1--1221---11-22221-1--2--11---2221--221332232222233456223334332222222222213333423424322442535434446534323423334434444444433324254--2-------------1-1--1-------311212-11-113222122333---13333333121134----1111221123-1111--2---1------342---2121-121311111---1--221-223331112----------------------2222---342-3-1211211---1111-1--1--212323-------22-2-222222222222-22222222222222222222322223222212222222222124212222222344444444444223-22222222242422------------------1-------3-----1-----------2222222222-----------2--32222223232222--1-332222--------222-----------2------2------33333313332322 12---1-111----11112-1111-11--1-------121111---1112121212111121-12--------1--2-1-----1-1-11311-------1-1211-1516-3211-1----22---1-261-113-11-11111-111-1---12112-132111-3-1313113233k454345236134223--13 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.80.6 Stabilizer of iron transporter SufD
[ 598] -------------------------------------------------------------------- 1-1--------------------------------------1-11----------------------11-1----------------------------------------------------2-----------2---2-----924222------------1-12231--------------1---------------------------------1----------------------------------------------------------------------------------------------------------1-----------1------------------------------------11--------1-------------------------1---1------------2----------1---------------------------------------------------------------------------------------------------------------1------------------------1--------------------1--2----------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------1------1--------------------------------------------------------1 5411593-HCC485823728565767456414454296785676-4473572584259557762133325443684313-54336666-A75376E57273478B946JALBGCEGJHOEEALFSRNWLe*F1FFZJGGAB8FFGGBIBGGF9UICD6B47GA88B6A8CK44L84E98*55-86C3646A7-58B79A ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.69.13 Oligoxyloglucan reducing end-specific cellobiohydrolase
[ 599] 1111-11111111111111111233222222411122222222222322233212221211111--11 2121221111112122222-42112222222222222222122222222332222323--2221322232111111111---221311111111---11-112322121-------111-----21121132122212113232122422222222222232222223621222111212212372222-222444444531344444224422434222222222222233122212222222222322221-1-22-----1111221---1-222---111122222222222222-------------2114411111221211111111211312211112121-22122224322112222221-22132113-----113222113221211111111112-22122123322-2332222222222111333223223221111111111111221-----------------------------11212111111233332232332222333323322344212444322422233222222111211111111111222214111211111111111111211222222222111-11112-11-1111112111211223211232122222323222222233233--1122211-11133332333333333333-3333333333333333333333332223332333343323233333333332-32133442333311-3-----122222422111112-11111-11222222311121222223222223232221--11111-23333222223333311113111111111221-221122--------2-1----1-111211111111111111111211212221312 ----1-1---2-11111111121122111321122112212111112222223322122221122111-1111131233211121111112112112122132211-121312241-311111-24141BL3-317-1-11122-1111-2--612113--11512-----253-321191112241261433123221 ----------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.27.1 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
[ 600] --------------------------------------------------1---------------1- --4-------------------11-----------------221-----------------------1-1---------------------------------1--------------------------------11-1----12--1121-------------1--2--------------------------------------------------------------1---------------------------------------------------------------------------------------------1---------------------------------1------2--------------------------------------------1--------------------------1-----------------1------------------------1-----------------------------------------------------------------1-------------------------------1------------------2-----------------------------------1-------------------------------------112--1-1111111111-1111111111111--11-1111-----1111111111111111-1111111-----------------1------------------------------------11----------------------------------------------1----------------------------------------------------------------------- 6427B961SCA6B9H572646542514555344239242345427856874568675655535545266535448664B52553856464487436453735B547-75HFBFECELC8878CJIE9NAj*N3TNZ89BEBAAQA7D9AEF8AP8FB898GJ6FB59IFAK78D94969S95637C46H8677A5DA7E --------------------------------------------------------------------------------------------------------------------------------------------------------------------------3---- * b.69.11 Putative isomerase YbhE
[ 601] 11-1--1111111111-11211211--11211111111112111111111211111-----2--1-11 2131211222211131111-121114111111211133332113242-211123111111121-24423211111111-11-111111111112---11-211311212--------------111121111111111111111111111111111111111111121111111111111112111111-111111111111111111211111111122111111111122111111111111111111121--------------------1-111-------11111111111111-------------111222111-14-24111111111121112---2-1--1211122111111111111--12136444-33-3536771134543333333333226-33433537951-6554536666875522234523444352122222251122111--------11-------------------2226222552757767563333558B333334558775512552326336563A9221132321334333311131112211111111111-1111113111111-3111111111112111111111111111222244324-3423533432344443333433-1-121111111133213314222422222-2232222222233223222222211133232323333323222322222221-22222222222211-------111122446111111-1111111155555331115233233344333355333121212212121312222222134223333333322221111111111-----1--------------------------------1--1-111131- ------1-----1-134224464575522222222222222222232334344634333222212111111111111-1131112111123242222222122222--4---2-1-1----1-1-1--------------1-----1-1----31---1----1-1--1--1-1-1111I11111D1342241232442 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.334.1 IlvD/EDD N-terminal domain-like
[ 602] ------------------------1---111--------------1---1111-----1--111--11 2222312322312121111-1111111-11111121222312422-223112123222113322321324311111111112111221554422222112223223323211111132222222222232222222223311121221222221113112232323223322212222212222222-1113222222222222222222333222222111112-----1111111111111111111111111----211-1111--112-12111111-1111--11111111111-------1-----11----1111-3133222222222221111111223-12211144-1-131-1111-2121-33332222243333333233333333333333331443453433432233333322233323332223233322333333333333332311111111-1112222222222222111113322122223222222212223332222223233224333333222222222222221232221111111222222123331111111112-1-211--11121245-211111111111111111112212222222222211222222222322222222222--13222-1----22222212222222222-2222222222222222222222221122322222222222222222222221-222222222222--12111111111222321111221111-111122222122233222222323222222443122212212222222222222222223232222211212222332222222222222-211112-222222222212222222221221213221133 11--111131----1------------1------2-------------1111--11--------1--1--1----------------1-----1-3-------121-25242233112323232441437X6-34632222443322422521324334--61514-1---21412222R232225115-31223112- ----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.173.1 Methionine synthase activation domain-like
[ 603] ----1--11212--1-1-1111111--1-1-----111222221213111121--11-1-1---11-1 -11-111111111-11111-12112211111-22222233121131-1-221122111--11122135221-111----11121-1112222-211---1311121312--------------1111111112-1144142221-2121222--111---11-2-1112-------------121------12223233332333333--22113332332-32333333241111111111111112112111112311-1122111131211223411131112111111111111112222111111212111111112--1222222222121122222221--11-112-11121---11----1111-1211------223221-11212211111111111-22523422161-22223343421322-1----1-11---11111111-1112322------------1-11-1111-11-------122-111-1222222221112222222211223343412322332224342423221-211---------121121121-111-212221222222112112111111111-1111111111111111122-11222----12-111111122111121211111--1--1------23122222222222222-22222222222223222223332222-2222222222232222422222221122222222222211-1-----2222-121311111111111111122212221112233334343133321444-----1--------11111-1---11222222221111----11--11--------1----------------------------111111111-111 2---331-935-112BBK9J778B89E7666687B65796555777B5EHKDJGADAG6C9C443333233135354144333343222382B9372233121574-242------------------------------------------------------------1---1-4639-1---3323C321255791 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.17.3 Magnesium transport protein CorA, transmembrane region
[ 604] -------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------1111111--1-1------------------1------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------1---------------------11-111--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 1-1122A-521-5553333333344333343333323333333333333444443333333345645515755457727755555533335333344443333CBB2768DWWQlIQLGK9LJFgcFfL**R-aGqJJGILHLPEDJLIEkB9lLPIOL38K6A9849569CH98132271111132323122152241 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.42.6 MIR domain
[ 605] ----1--------------------------------------------------------------- ----1----------------------------------------1-------------------1-1--------------------------------------------------------------------111--------------------------------------------71----------------------------------------------1---------------------------------------------------------------------------------------------------------------------------1-------------------------------------1--------------------------------------1--------------1-------------------------------------------------------1----1--------1-----------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------7-----2-----1-11-----------------------------------------------------------------------------------------------------1-----1--- -----13--1-1-----1--1-1--------------------111-----41--------1------------1--------------------1-1---------124PfibZmVSNLOTfM*fRnY**x-pc*NTSOZISdRJWQPMcJCiNWMRQA9835843A57533H2-----------22---5-22636- -------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------- * b.42.1 Cytokine
[ 606] ---1--2122222222--1-----------1----22-1111-------11111-21----------- --1-2--1------32222-42112322222233332233-32221---11---1-----111-3122121--------1--1--1--------------2----12---------1111111------1---2-2111-1111-21311111222--1--121132123------------11111---82211111211-11121111--22111112----------13------------------------------------------------------------------------------------------1-----------1-1--21-221--3-----423-3-2---1-1-11-----12221-----223221113322411111111112-22322322142-31143243232134-1-33311122231-111111--1-1323-----------------------------1-1---222231222223333222433233224342323--22211212122-32-1------------------112----1-2-2111--1------1-----53-12--------------------11-1------1311-11-----------------11--11233------22221222223233322-2222333222232332222233231111111111111111111222222222-111111111111---------121312233---------------2211211---1211-11231-1221-333122222222----22222222222--------------1-1-------------------------1--1------------------------11-- -1--445-8521334356267556585221334253645443425344677B795758522243242222223232222222222211124355473221242222-7M4IBD79966546454B9783Hf5-9692465534457433564785665842246978A52323734CE2B33367Efjp6RD5524335 ---------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------- * d.269.1 Gamma-glutamyl cyclotransferase-like
[ 607] ----2----------111--1--21-------------2111-1---1-5967-12221111111-23 114-2-43322-3134433-353344333335655524331234---1-----11-----11423523133----------211-13156443322---1212222323---------------22343433333333321112-11211111-112221-121-112-1222222222222422--22-14-11111111121111134111-1124533-11111111311--------------------1-1--1-11111----11--11211---111111-11111111111------11-111-111111111-251143333333232-2222---323-13231-CG251452172232122111222211111244565424344533333332332-334334343341433333433355445323333333433222222221--21116-----11111---111--1------1111-3333-2222343334332333333433332324233343333333333343323334222222----1--22243326722223121321-232332225111233211--1-111111---------21212112221222122232222322222222322331-12322---111211111-1221111111-211122112121211111211111111121111111111111111-21111--211111111111--12-----11112223311112211111111132222-122222222223332323223221111111112222322222321321111111111-----232453333--------1-1---11---1------1111---11-42234-2-1--232 ---1223-42--1-21-1-111-213-11-1111111222222-11-21---2-2212111111211111112-1111111-1111111--1-211-----1-2-1-23342235211323233362328P3-3552111322342321232331322725722221-1-1252--121L1212-1--32112324232 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.23.6 Cobalamin (vitamin B12)-binding domain
[ 608] 223-1-789998A989--21111-2---1--------------------------------1----1- 13A24---------1--11-12--5711111433331369231311---11-2121----1-B-34B555--------1---41--1-------------1-256-5----------------------------44433----A-1-111-------------1-1-2--------------23-------1-----1---------12---1----21-----------1--------------------1----------------------------------------------------------------------54-24444344434-5------31-21-112-312332-2-3-------4--4332-----24HIJ413586B61111-11-111-A9F88EBE783-52241194317C8523-881444467844444444A4331521------------------------------2351-55435ABBBBA22221BBCC22221285GCAD4-2665444118261B2131-1111-----------2211-4-4121121111--1113111311-133-4-------------------------222--4112-51112222232111111--1-1----1---------1--2--3332322232-3333212323323332331------------------------51--1112-----------------------------321---------------1111111-214166663284454553423---------1---3----------1123233----------2--------------11---------------------------2222-----13-- ----112----411-21332121121222232211111111112221211122311211111-----------1-----1-----------11-------1-1----243A23235A2222352DD352292-32422225236222233C2292624526O2763B69DCF354-13-9---2354862971121112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.41.1 CO dehydrogenase molybdoprotein N-domain-like
[ 609] --111-1111111111----1--11222-111----1122222--111-2----1211-11121--11 -1--11-1111-1-21122-21111222222-12222112-11-12122111111221--112-11-2111-111---1--12---11112212-----11112-2111--------------11211111221122222--1121232332122211111223122111111111111121112-133122233334333333333322335333322334222222223422222222222222222222411122223222222222112212323332222322222222222222322322222222311222111255122222333222243443333333121233354344112234455221123111111111--------1511111-11111----11-11-1-11111111111111-11-1-1--11111-1-11111111-111-112--1111111----------------111111111-22221111111211111122111121112112122222122111112112232223322122222222222-3212333235334264657543343332312------------1-------1---1--2222212121222222223222222222322-111121--22222232222222222122-2222222222222222222222222222222222222222222222222222-2222222222221-21-1--1----212-11112122----11122222212111212222122221111222221121211112222222222222222222222222222---1221122---------11----1---1--11----1111-111-111-323331121 11----2-1-1-233232-222231322222222323233133222322331211113333333233121333-333-233444232222423346434322-453-44-64321333123331532418U3-43322113--321321432-31422124-14211222I31311---7-11211-412-21487662 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.98.2 HprK N-terminal domain-like
[ 610] ---------------------------11--------------------------------------- 1111312222222211112-11111111111111111211111121111221122112111111212222211112122111211111111111111--111111111111111111111111111111111111111111-11111111111111111211111111111111111111111111111112222222222222222222222222222231112222221211111111111111122212122122122222222222222222222221111122222222222221111111111111222222222212112111111111112331111111111111111111-11111111111112111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111-1111111111111111111111111111-111111111111111111121111111111112111111111211111111111111111111111111222221111111111111-11111-1111111111111111121111121111111111111111111111111111111111111111111111111111111111111111121111111-111111111111111111111111111111111 ---1143-----33521111211212111111112111111111111211212122111111211111-11-11111-111111216444B31855112243267A22A2A89AIB97442666FD6H4Ha6486955446676665725853G8665718G5A5328378-2234346c77555C63M1W5782333B ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.59.1 PAH2 domain
[ 611] 11323241222222214113333321111411434456764463244511577554353852123-11 33512-1-------13122-21--44222222433213323343-1--1-----------22222224341--------332145442111111--1---21--22211--------------1322333123434446555532335433211221111112312332211111111211111111111-1-1111111111112111---1-211111----------11------------------------------------------------------------------------------------------1-11211111111-13-------1-1--2--3477211-1-32--211--36-111111111535351114753511111111111-11111111111121114222212244111113444411122222222633126241111111111111111111111111111111112-11111111111122221113323322134116411111331111326111143111211111111113256134-62336545561847877818556514184333244444323222222233746663311------111111-11111112111111--231311111132344215554544455-5555544555545555455222311135554555555545444254444551-31111111111111111111122224-11-111121---------11111111113-1111111111111-1112111111112--------------11111112111111115-222222--------1---------------------------121111-11-4621 ----111-211-11221211132234122121222222221222111111233211223111111----11-111------11111---12111112111211112-1-33211111-----1-22-2-4J1-321----3--2------1--2-1121111211134212112111112---2124-61131235251 ------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ * e.19.1 HydA/Nqo6-like
[ 612] -----------------------1--------1----------------------------------- ----1----------------------------------------------------------------------------------------------------1-1------------------------------------------------------------1--------------1-----------------------------1----------------1---------------------1---------------------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1----------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------1--1-------------------------------------------------------11------------------11--11--------1----------------------------------------- 6533675-E54267656655556566555666655465556555666454554645464666666666478666576466677787333454644443444458562787GHMDGJDECDDEEBSNDSCu*I2PMkACECKDEK9BCDBBFABJEDBCD7AD6B678B67B8AB83445*55555CALC6B67856567 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.2.7 Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
[ 613] ----------------------------------2--------8D--6--FB2--------------- ----2--------------------------------------------1-------------------2------------------111---1-----1-11B31-1--------------------------1-----------1-----1-----------------------------1---------ABB9C899-A9A99956----AAB---3-11577645-5-55535555555554-------2----2---------------------11-1--------------1111111111111------------------------4----7223-7---1--------1-------1------------------11111111111-----------------------------1--11--1---------------------------------------------------------------------------------------------------------------------1--------------------------------------2------------------------------------11--------------1------1---------------------------------------------------------------------------------------------------------------------------------------------------------1-----1-----------------------------------------------------------------------------------------------------2-1 21-1127-632243A55455455544544423234525344653433313323222253112132436325323366266222243322372561122131318A8-423MKULXON9FD58MBYICW5j*G2KLX9FDAKADKF3J9B5M76VEFCFG6B49623796358D52111171111256554721112124 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.1.28 NEAT domain-like
[ 614] 21-----344444411-122-1-62--2-111----------1----1----1--------123-1-- -1-291-2221---45433-38118633333577794988332222122--22121----86417186963-------1--1222112-----1------------2-1-----------------1---1----23354---5-3224222--1131111211112231121111111111---1111-1-111111111112111122111111212-31---111--31--------------------22--11--11122--113-2-111--111------------------1----11-------11---111---1-1-------1-11111----2-1--223--121-1-11-------1----3224-----1-211--13113211111111112---3-----122-1111--11--21311222122322124--------1---1122-------------------------------1112-22211----11-111---1111111---2444-13321--121-13-21-121--12----------111-A18----1-------1-------222237---------------------------23332231422123333323623324456255--11121------22222213333333333-3333433333333333333224221122333323222332333432222232-222222222222--1211111111122432111-1-1----111122332232233155554353544565333---------123333333322455111111111111111-12-------------------------------------------3----------1- ----231-1--14351111221163512211111212232222111241211-221211111111--2-2--11111111-22212---21312111111222534-89-A7655898545775EB599KzC2D9G3344A589636644844946734B854A53245A67546-12-1-1-113312111--5445- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.106.1 SCP-like
[ 615] --------21111111-2--------------------1----11-2---11------1-----1-1- ----11-------2111----3--11-----122521----122--1--11-------11--1211-3351--------111-1-------------1-----31------------1------------1----1--13111--31-111------------1-1-11-32-----11--------------11222-21-111---1-----212--------------------------------------------------------------------------------------------------------------------1-----11---------1----12--1---------1--21-111---------1111----12------------11111-11-1----------------2-2---1-11--111111111-111-1-1----------11--11----------------1---1----111---1111---11111-12--1-1-------------2-1---21-----1111111----1112----11-41112-1---1----2222-----11----------------------------------------------------------111--------------------------------------------------------1---------1--------------------------------1--------------------------------------1-111-----111-------------------------------11111-1---2--11---------------1------------------------------------ 11--55615322C6B45244666777777673777666565665675545664678736455454465246644655255455545454-B1565563652356161983LEGBDMGBF798CBFH9I6W*E2GCP9997E8AE87BA77C99IACCB85DJ97665D537DG452421L23263EYqZ4YA3248573 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.129.6 KA1-like
[ 616] -----------------------111111111-----------1111111111-1------111---- 1211211111111112112-121112111111222211112111222222222222222222222213222222222211111111112222122221-222225232211111111111111111111111111121111111122232222222222222232222222222222222221111111132222222222222222222222222222212222222222222222222222222222222222223222222222222222222222222222222222222222222222222222222222222222212132222222232231333433232111221122111121111111111113222222222223222222222222222222222-22223222222222222222222222222222222222322222222222223221111111111112222222222222111112232222222222222222222223222222232222222222222222232222221121222222222111222112211111111111111111111111122111111111111111111111111111223322222322223333422335323223321-2322211111122222222222222222-22222222222222222222222233322222222222232222222222221422222222222112222222322232224222222222112222222122222222222232222222322222222222222343333333333343222222222232322211122111111111111211112-222222222222222222311121111111222 11-----11---11------1------11111111211111-121------1--22------------1-----1---------------12--12--------21--4-1-1124-422213165-414B31235213332221413113-1131221111-4-1-----112-1-118111321443-412221--2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.68.10 GyrA/ParC C-terminal domain-like
[ 617] 22222222222222221222211222222222222222222222222222222222222322222222 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111121111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111211111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111211111-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111121111111-111111111111111111111111111111111 5422443-F552332323333343233332333333232323354432233233333322222232231334233243223444335553532343433331387C237493842354475364BI3F27O8-64A5243933654356233643244447333433343444334444a54445I89C3854434334 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.12.1 Ribosomal proteins L15p and L18e
[ 618] 11---11---------211----132222222------------------------------22---1 ---22212--17-142233-72222233333224443333-22-232-2222223232------223242-----------------------1----------1--3---1-1---------------1---32--------1321--------------------1--------------22222--------------1-------111-----111---1--------111111111111111111-1--------------------------------------------------------------1--------1--11111122-1--------------2---111112-1-1---------2-222222222242222222222222222222222-22222323233222222322422222223244524422222222222222-22222222222212222222322222222222222222-222292222222222244242222-2223222222442222223222343242-2-5322222222224231-1--111122111-1-11111-1111131-11231211111112111211112112--442222222244556534444464344744--22332------444444344444454DI-444B446B4F44444444444444444454444444444444344544444324444444444442222222222223222222222222222222222222222222222232322222222232222222222224444444444444422222222222222----111121--------------------1----------------------------- --11421-1---221235112313223443333333433333411122245444332121111212321121-212222221113111113231121221121312-1415233232-21112141171EK9-1-4121-4111-1211-1113111241--153323111-1422112111211-35B12-213121- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.21.2 Fumarate reductase respiratory complex transmembrane subunits
[ 619] --------------------------------------------------1----------------- --1-------------------11------------------1---------------11---------------111--------------------------------------1-------------1--------2-------------------------------------------------------------1----------------------------1---------------------------------------1---------------11-------------------------------------1----------------------------------------------------------------1--------------------------------------------------------1------------------------------------------------------------------------------------------------2-----------------------1----------------------2---------------------------------------------------------------1-----------------------------------------------------111-------------------------------------------------------------------------1-----------------------------3---------------11111----------------1-1------------------------------------------------------------ 2122CD5-21-1445666655556567556554545565555555577557887666766764444444467634775884444466665C566794445556D98-A14BORIWKICBCBDDBdTBUC**Q5UJdBBCAKCCE87DCC9FCAYCCDEB5BG776C885494C773524Z4452CB79B6F6-122331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.338.1 Oxysterol-binding protein-like
[ 620] --1---------------1-----22222222111---1111111111-1111-------------12 2213121133112222222-23112222222123243222222224221321111211112232322111211111111232211111111111112--26354332441111111111111133111A3112332222111112745233211112222214423342212222222122211111112113545553353246444222223464111322233333332122222222222212322223232222322243222222222222222222222222222222222222222222222222222222222144233333543232224422223113231211553212221111111313137444------14342135632A2212121-111-1--2-12112811---122322-233518--1111---111111111-113-1-1111---------1132115211111111-1866711----222223311112222321222222222212---1------112-1111112213433133-11222222321212422221332221312333352211111111111111111111121112--1111212111-1111111111131111211----12-------1211-222222222222-2222222222222222223222111112222222222122222122222221-111111111111---5212222D5412413-------------------------2111111111111112111221-21222111-111111311122122322111-------211111111111111111111-1-111111111111211111112111111111713 --11--1-11111111111111111111111111111111111111-C11112-11-111212-11111-11111-11111111-11111-11-11111--11-12-17-831311-11---1-11-21574---21---2111--1---1--21--1D1211112-111-111125I2B345223526143-211--- ---1---------------1-1-------------111-4----------------------------------------------------------------------------------------------------------------------------------12--- * d.226.1 GIY-YIG endonuclease
[ 621] ----------------------------------------------1--------------------- -1--1--------------------------------------------------------------------------------------1----------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------1---------------------------------------------1---------------------------------------------------1--------------------------------------------------------1----------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5135346-N82-686556568888679554535666555535544525557668675565556755454574555553554555465448C556553344597997-CZ9JFGCDAFCA99BAALH9EAY*F2FCJA9B8GABEB9D997B95FCB89B75E9H6YFXYfKCF9D4F95e54374MNSh4aG7665762 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.5.3 CRAL/TRIO N-terminal domain
[ 622] --11111--------113111123-----1--21111112221222222211131211222--11--1 ---13-11----1-11111-11--1111111111111111--11--------2-------11211222211-------1--111----11---1-1--------2-12----------------2--12111111133-1111--23222321122111111-3221143--1---------1111111--11-----1---------1222-1--1-2211--11111122---------------11111-------------11---------------------------------------------1---------112111111111-1111111--1111---1112--3-2-11-11111-1111-122------121111112222211111111111-32222222-1--2111112111111111-111113211122222222211-2213--------1--1-----------------1-112-----11111111111122111111111221111--1111111-11112112111111----11--22-111-22213142133321112311311-----1-1-----------11-------1111111--21211-11111111-1111111211132---111-------2---2-1-----1-2--1----1---2--1-------111--12-1111111111111111--------1-1111-1111------2-----1---11211-----------------1-------1211112111121111111----------122111111121111-221221111111--1-112222--------2----------------------------11112-213121- 1222213-532-3342254233234242222123445444423412326355451344233222321422213223224223333242447425355543334354-2869EDLDEA7564475LQ3E7n*9-DCI4667B976439775E55G9B86745C53444AA6G79333494V45523C8CE2B52446772 -------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------- * e.50.1 AF1104-like
[ 623] -------1--------------------------1--------------------------------- 15B-1----------11----1--11-----111111211-----1-----11111-1--111-2221222----1--1112----1178C5-9-----2H264V3T6C---------------------------------11----111---------------1--------------------1---11112121121112111794423211-333222111211A*122222222222222122112----------1111----1--1---3334233211222123322222333333333333111---111-574-D1111111212C2224453I31--1142168121-2-233-3A-21A2------111----------2-1--------------------11--------------21-1---------------------------2------------------------------22221----1------11111----1111-11--2121--1111122221232211111114----------11121-----11-11111--1-11-2--1-312--11-----1-------------1---1--43211732221122222111221111-113----2-1------33451333334333433-3323334333343333333333433143233333333233333333322321-322222222222---1----------12-111111111111111111111-1-2--111111---1-1-11111----------2334333333433335423242221111-1--33----1-----------------------------------11-11-1----7-3 1111121-54312-21-1---1-211211----1--1----------112----22--1---1-11-------1-1----------1--221-224--11121-2--111D57786674498A8GK7I6P*C1H6G8566B49D978354H55K452775552231152122242112-3-21--H66211-2-3221- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.24.8 Proteasome activator
[ 624] ------------------------1--------------------------------1-1-------- -----------1-11------------------------------------------------------------------------------------------3-----------------------------------------------------1-----------------------1----1------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------11111----------------------------------------111-111-------1------1---------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------1---11----1--------------------------------------1------1111111111-1111111121111111111-------------------------111--11-----------------------------------------------11--11-----------1------------------------------------------1------------------------------------------------------------------ -2------1----1---1--1--1-12-------1--121---2--31-1--1-----2----11111-1111-111-11111111111----11-1-1--1--------ZZicmYLMBIIMAN*eCvO**v8*TH7KLHYMLl74RUGJU34sQRBEJFMV4662395337B1----11-1--1------112-1-1- ------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------ * e.69.1 Poly(A) polymerase catalytic subunit-like
[ 625] 22222222222222222222222222222222222222222222222622232222222222212222 12211-----------------------------------1---11--1--1-1--------1-1--11--1111-111------3-12111-111-11--------2-1111111222----2----------2---------1-1--11-----------1-------------------2222222-21111111111111111111--111111111-1122222211--------------------1--------------------------------1--1--111-1-1-11111111111111---------11--1333232223313113222542441111111--1-3111331122211211111----213121111211211111111-11-2222212222112111223121111-1112113333111---------111-121-------------1-------------------1-122212111322323222213334141141111--1121231111-22111221114--------121-12111-121111-2212------3113543--1-1111------112-1---221111---14---1----2-41212-1---2--1111--1-3111--1---2-121131331111111-3211211111313-11--1---2232244444444344444441-1121124-455555355353--2-------1211-512---------1---------------1132-31---1-----121-------------21111113-----11-11---------121111--22222222244------1211-2----31--221111--113113111-- 1222218-83111111111122111121111121112111111-111111221211111111111111-111111111111111111111211212111111111211527DGKKG95484686FH4Q6l*K3OCO7676B68A865964A84M5C89C31723334821756241111A1221143521412431331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.24.11 Bacterial GAP domain
[ 626] -------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111111---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------1-------------------------------------*hcVORWPMRJSVQeXOPL**X1pS*KSNNaOSZV6TGNJRIHrPkRUN7AE635G9FKEBBHn6-------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.28.1 Thyroglobulin type-1 domain
[ 627] --11----------------12--111111-111111111111-----21---11112-1-----111 --------1--------------------------1-11------111----1---2-----1---21--------------31-112--------------111113------------------11-1----2-1112----261-11113322321331-3-1576412-----2-11------1-112--1-11-1--111121--1113--1111311-------2-222222222222222212213-------------------------------------------------------------------------------11-1-------------31---2------1-4-----1-1-2-3--2132232-7447245444412221222227-56166353662-6338336736751623114-1111412------------1223-----------------------------14222-11111---------------------------------12-11-1112122-21-1-111111111242--221134132423421113231-13---11111--1--111121----------1------1--1-----2-------1----1-1--1---13--1-------1----1-11--1-1---1---1----111-------111-------------11-1-----1122--1-----1----------31--------12-1-1111111-11111111--11------6111211111111112111---------1---------1------11112--------121----11----------1------22-22112221--122---21112-2-----12 34--544-C644446155556666666555545666566666663656655556546556665461111611556211111666566666A657655457565666-485C647AD745464656B563Cn6-6974546636C335644644A12-43686545475B6554754467f7436169AC5C6768B673 -----------------------11-----------------------------------------------------------------------------------------------------1----------------------------------------------1- * b.40.1 Staphylococcal nuclease
[ 628] ---1-21-1111-21-11111211222313-1231222232232314333133-3422112---2-1- 265-521233411112211-11--2311111133231324133414321111333241--63321143422-1111----2-11212266731A33---2222143321--------------12211112122122222---21421411122222222221236223422123222232311-1-22-1232334423324232423122233353322543------652111111111111111---1------------------1---1--1----111----3311111-122222222212222-----1---222-13111121112121222111212122----33421314--1-121--422222311111314423221112422222222212-33243523422-3222223222231111121-12112211111111122211322------------11111111111111-2-1342212443332232221111335222221233512211121231121-1121--152-1231-------22144313234222223222362422422345352542222221-11---2-------22131313121223211121232-112211-211-21---2212------32322222222233332-22222232222322222222222343322222222223323222222111321222222222222--1133333----143241112111----1--22222223223524434335342322-323-111111112--222222221-2222323222222222--22111111------------------------------------11121111111113 1-22-11-11--1126222-231435211--11---1111211---1-12552312-212222--------------------------12121112121111313-142213215111111112211-131-11-11111111-1111-1122-111211111132111811312331I2111255641711323112 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * c.26.3 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
[ 629] -------------------------------------------------------------------- 1-12-11111111-11111-111111111111111111--32231-1--11--1111---11------2--111111111112111111111-1--11-1---11--211111111111111112222222212211112111-17334654123325333434342143422434324344323221112211111111111111111-11111111111111111111231---------------111111-----1-1-11111111111-111111111111111111111111----------1--1--111---112434222223223213113222221-24222232222122-21111111--4---2-------22331---2-3--------1-1-241-11221111-----1222-1--11-211--2--11---------311-131111111111111111111111111111111111111----121111211111332311111112212121131113111122311111121111111111122221111-11-1211-----211111222-11123222112222222222222222222233---111313111111111111111111111111--2111-11---1111111111-111111-111112111111111111111111111111111111111111111111111111111111111111-11-----111121111111111112-111111111111111211113111111111211111211111111111111111111111111111111111111-11----111111-21-146B3--1-----------------11121111111211- 3311353-F66-11211221-1222222222222222222222211222222331222222231422312333313323433332121232212222222221344-26274333455454214873649c61676314342343233535434333243432255533552532357A*A9A97GALI2GD3322227 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.269.1 FtsH protease domain-like
[ 630] --1-12-----------------1----1----1111--1--------------1---111------- 211-111111111111211-121121111112232311111---11-11-----------11--212111-1---11111-11---111111111211-1111111111211111121211111222222222211111111112-111111122211121111211111111112111122-----111-12222222222222222211122222111112122221121211111111111111211111313443121255225543333211133334342223333333333344444444444442221113334111311111111111112223221111-111-111112111111111121111111121111111111111111111111111111-22122111-21121112221222211-11----1-----1111111111211211----1------1-----------------1--1-12222222222222222222222222222222222222223222212222222122112---11--11212211-11111-1122--22212211111213-11111-11111111-1111111111--221111211311212222222111221222111-1221111122213221221222122212-21112221212212212211212221111111111111111112112111112111111111111121122222221222112223233311223222222222211221222222222222222221111111111222122222222221121212222111111111111-1222--1--112-------21-11----11--1----111-1111111211 2211332-52212221122332432332212-1211133332323311332222232232222232221122222121322222223322121232332322223222632454722-12235364351Ll517351431623423441261264214146A42341634753214123K4343352763443223234 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.29.8 Bacteriocin immunity protein-like
[ 631] --------------------------------------------1--1-211------11-------- -1------------------------------------------------------------1-1--1--------------------------------1-----1----------------------------------------------------------------------------------1---------11---11-1------111-------------2---------------------------------------------------------11111111111--------------------------1----------------------------1------------1-------111-111111111111111111--1-1-1111--1111121112--111111111111--11-11--1-1-11--------1---111---------------12---------1-1111-2--11111111-11111111111111111111111122111111111111111111211111111111111112--------------------------------1------------------------111111-1111111111111111111211112--111-1------1111111111111-111-1111111111111-11111111111111111111111111111111111111-111111111111--1111111----111111111111111-1111111111111111111111111111111111-11-11--111111111111111111111111111111-1-11--11----------------------------------------1--------- -----1--------------1-2-11--1-------------------2------1-2---1---------------1-----------------------------11-LlqZbiQKEFCIQJcXFaGt*T-ROjAKEEUCOWN8MID9OD9eKWORa7GH23741433645F4----------212--1---1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.40.3 TIMP-like
[ 632] 221-2------------2-2--115334J7251114P71111123132122116HCE6M6C1111-11 ---242--11----12144-42442444444-22-2335611311--------1------522-6216314----1----1--11421------------2---6-13------------------1--1-1-3-1112----5125533452222------3317445G------------111671--1-2-----1----1-421-----51-2----1--------4-----------------12--------------2---------------------------------------------------------21--2--------1-2-22----1-H--1--122131----1----2--1-311-------1---2----------1-11111111-13542431----2--21-111-1--1---8B211111FHNNNNNNNN7118713---------------------------------------------1------1-1--------1---1--1-----1--312-13-------1-6931554------13-1-111121211-------1--1---81-1-----------------------11--1--1--------111111--------2------1531-----------1------------------------------------471----------------1---111----1-1111--111--1-1111211112-2-1---------------321121-11-1------211-1----23---------------11111-1-----------------------1167-------------------------------------------------- --11116-----84626C489I78C8A556858997663865842455NZ8695236A52111-1-----22211111111---2-111---6-2-1111-13-2--3U1C4566733331233352344G4-544-44231353233213233343442231391221166D8-G-3-811121B121A1S--1---3 ---------1------------------------------1-----------------------------------------------------1-------1-----------------------1----------------------------------------1----2-- * b.86.1 Hedgehog/intein (Hint) domain
[ 633] ---------------------------1---------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ----E6--------2-----------------------------------------------------------------------------------------1---12*jjghaaMFJDJRJdcGaLj*W1YRqEHJKYIOYJFLHIBQGFeQaVSSERa9BDD9JBDR7CU5---1--11--1-------1-1-1- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.141.1 Frizzled cysteine-rich domain
[ 634] -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------1111-----111-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2211DC4-945278B67967678696888776887776577577672466656566577787755675367464645467755546A995B67747535545AA9A3C7AJKMKQJEB779AB8JE7L4x*J2NES7765G6BGB6A969E58M4FEBB8DIAAB78OC8FACAB5453T23344GDER7PB3467873 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.221.1 Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
[ 635] --21121---------31-----3223221213332221-2223544526445122124221111-11 313-233333433323233-33223333333333333333111133214224434412222232223222322221112364112222121111221--4222223112--------------1452524422336446722421442222211-----1---14-4211------------333221312213333333333333331-2221323333112122222221133333333333323233233-212313-1-4422442111414242224222233222222222222222222221222222222222223344353555544526665254413242446435553351244251311152111211111112222232122211111111111-11111112211111111111111111211111323311111111111-112222411-1111111--11111111111111211-222221444111111221111-111111111111355422222122333-2241223112212111111111-223154343442563331414423126444412342--1111-1-111-1111111223233222112212112222222222222222222--11111------22332212222222122-2222222222222222222222112222222222222222222222222222-2222222223221121222222222213131112121111111113334232111322222-1111-1--111-111111111122232222222222221111111122231132112222--------31--------------------------13411131212432 -----------------------1--------1--------------------1-----------------------------------------1-1-1---------2-------------------------2-11-1----1--------------------1111---------1--------1-1-------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.34.1 C-terminal domain of transcriptional repressors
[ 636] ------1111111111--------12211111-----------1--11-2122--11----1----11 111-211111111123222-23--242222223333423311-122121112353111--1131112222111111112132------2111-1-----1412233232--------------2---111111-2-----111--4--------11111111-1-1----11-111-11111--------2-22323313113121211222232312-2222232222222222222222222222322226112222-21111--2321223121121111111111111111111211111111111111113322111121111111111-1-2111-111211211-111321-12221111111111-14111-----212231111121111111111111-23112312231-1222421223331112111121222221111111111111321-----------------------------11111-111111111111111111211111111111211-111112111142211111-11521111111113121111321212-22213-111112113--211121-1-11-----1-----1-----11122311321212111346323333221222122----11-------33111322222222422-22242222222322222225331111222121312314433233-122221--111111111211---21-1114332-2122111111--1--11112234211-111-112112131123221221-1111-1-1211211121211211111111121------2-11--11--------1-3----1-1-1-111111111111111-1--------2112 ----1-2-94A11-434223333444322222233333332331112434333323423333211212-12-11121-1123322133133242322222-22321-592844347E44343439A4B3Ce5-6773243543642443433593634431334543433934833332A3311434672A5423124- ---------------------1--------------------------------------------------------------------------------------------------------1------------------------------------------------ * d.240.1 Lesion bypass DNA polymerase (Y-family), little finger domain
[ 637] 1111112111111111111111111111111111111-111111111111111111111111112211 1341412233311132222-23112322222233333344134233431332322223113322226454311111111233111---222112112--13222423241111111111111111111111-11122223111323--211-1122111111--12212--1-----1----1111111111322222222122222232222222211132424344435311111111111111111111111-1111212111121111111212111111121111111111111-------------21111-11111121211111121113222-11-3121111111442111111111111111124442-1111214332213333333333323333-11111111241-3333332332331111112321222231111111122211112------------1-11122---12-----11141133323333333222323333212222733333411334121122122212221112521111111121211311111221121121121111111232242112111111112111112121221-1122431122312212332332232222232222---2111------33332423333333323-333333333333333333343445112333333333333333323333333--333333323333--12121112221123231111111111111113332313111234443344433333122211111111112223222221222233222222221111--11222222--------111-------1----------1-1----1211-111111221 ----111-211--1232221222121122111122212222222221223222212222111122-1--111112111111222111111222213-1111-1111-13-2-1111-111111112111251-111-1-12-111-11-1111-11-121---41--1--51271111-----2-1---2--1-11--1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * a.4.2 Methylated DNA-protein cysteine methyltransferase, C-terminal domain
[ 638] -------------------1-----------------------------------------------1 114-------------1------------------------------------------------------------------11212334314331--3444346435111111111111111111111111212----1----1-1---1--------------1---------------2121112----------------------------------1---------------------------------------------1-1-----------------------------11----1--11------------------------------1--1------1-1------2--------1-1132111----1---1--------------------------3-1--1-----------1---111111121111111111111122111211111111111--111111111111111111--1-11111111121111111111112111111112111111111111121211111111211111111121111112111242332222223222221311111411----------------1--------113211211131111222111111111121111-111-1------11111111111111111-111111111111111111111111111111111111111111121111111112111111111111111111112222112111111111111111111111111---1111111112121213111222222222111122222221211----------------11----111111111111----------1---------1-----11121111112112 -1-1116-C52411421134-352516966334253322223365823242462-42444242----3--1---2111111121-2-1-34-1623-1181231-4-A34P8JLK93B7738E6PG8Q9p*P7PHb4986H79HB16663I13D7BB6748E37431F6373283-573K113-192155313216781 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.48.1 OmpH-like
[ 639] -------------------------------------------------------------------- 223---------------------------------------------------------------1-1------------1-52611223313331--2222514232---------------22211122221----------421-2213311------112211121--1111-11-122222----121111112111111112422221111-1-2--------11-----------------------1--1----------------------------------------------------------------4211111222212111221111121--11-1111----2---2111--1321333322222213433333333333343232334-22443423335-3443335333442132433233333333333333313341534----------111111111111111-----65643433332222222222222222222122222333223334333343233244724345533333333344561743-335225222154534453511111154222222222222333333332212411443445444743444444444443464444--23336------44442344444443444-44544444444444444444444444444444444444444444444444431444444444444--254444488884564711112112221111222222212225555655443555555444111111111366666666678A7755555455555555--M12222222222222232----------------------------11111111---1 --------------------------------------------------------------------------------------------------------------1------------------------------------------------------1----------------------------1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.52 Sporulation related repeat
[ 640] -------------------------------------------------------------------- ----1311224-5------------1-----------111-----1-11----12--------5111222-1---2113---1----------------------------------------------------------------------------------------------------1-----3-37666666565665655B8BBA9765334128A25562612499989999999999555789A--65-161AGE--6A32543232355554444445555545554544444344434444664416664---6HBBBCBBC7A7-F--266611-4-212-----1------211--15---244---------------------------------1-----------------------------------------------------------------------------------1--------111111111112222111111211--1-----1------------------4----------------------------------------------------------------------1--88A-------61111112-111111--111-------11-1119E962E5777889A988-7778989889798887887DECDC6664644454454444444976477772-A44334443444--1---------------111352-----2--5------------11212423-------------------56665555556744-----------------9------34233333--1----B-3172522222276232111-------------- -----------------------------------------------------------------------------------------------------------------------1---1-------------------1-1-----------------2----------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.95.1 Glucose permease domain IIB
[ 641] 11111111122111211111111111111111111111111111111111111111111111111111 1111111111121111111-1111111111111111111111111111111111111111121111111111111111111111111111111211111122121211211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111121111111111111111111111111-1111111111111111111111111111111111111111111111111111111111112311111111111111111111111111111111111111111111111111111111111111111111112111111211111111111111122122112111111113111111111112111111112111121111111111111121111111111111111112211211111111111111111111111111211111111111111111122221111111111111111111111111111111111111111111211112111111111211111112111121111112111111111111111111121111111111111111111111111111111111111111111111211111111111-11111111111111111111111116111111111111111111111111111111111111111111111111111111111111121111111111111111111111121111111111111111111111111111211111111111111111111111111111112111111111121111111-111111111111111111211211111111111 24213362832221322242323323334331425422422222224332423242223224222232-22122333434233323234262233322221324551272C564753445163287372Hd5155A1534646982441142272434534427322454D42333543Y3344487F94742234223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.22.1 Ribosomal protein L4
[ 642] 11111211111111111111111222222222111111111112222221333111111111112-11 2221222222222222233-33223233333333332222222223222222222222222222222233211111111111111111112111111--1211111111111111111111111111111111111111111111222111111111111111111222111111111111111111111111111111111111111112211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122232222232323122212221221111121112211212111111112111221-----112221111122211111111111-222222211111111111111111111121111111141111111112211111111------111111111111111111111111111111111115111111111111111111111111111211111112111111112111211111111112111111111111111111111111111111131211-1111111111111111111111111111111111111111111111111111111-1111111-11111111111111111111-111211121111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111321211111111111111111111111111111------------------1------11121111111111 12-1422-31132222223235232423322223332323323222223222324322233343333313433443333335544422212124261122132222125144432443434243A83B2If5-8682323734633334373382353444223521333212222223G32332364A3AD2232222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.101.1 Undecaprenyl diphosphate synthase
[ 643] 111-111111111111--------52324-22----------------------11111111111--- 132121-----11112211-132231111112322221552222224212215643122222522684222----------191---11111-111----211111111--------------11111111111122222---24222222222221111111222222211111111112111-1111111111111111111111111111111111111111111111-11111111111111111111-----------------------------------------------------------------------11--1111111-1--111----1---11----22-1111111111-1--2-2211111111141221111112111231232224-332343313J2-A66575887AAB561116A53333EBJ1111111131114111----------------1------------81331-112212222223211122362222122332321--11331111111112--112-21111111111111111-1--111111111-1111111-1222223-------11-11-------------1-112211-15222232222222222222222221-1111211-11122222222332222222-32122222223222222222222222322222222222222222222222221222222222222111111111111111122111111111111111-1--1-1111313333333664433144411111111112222122222222211121221111111111-111111--------1-1-------------------------11111111112111 221111--521-11122222221222211111111111111-11113111222221211111111-21-111112-111111-1111111312112111111111--251F655556233333455443Eg415682422533412323342274334446525453347224531221K1121231232311231114 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.44.2 Aminomethyltransferase beta-barrel domain
[ 644] ------2--------1-----------------------111--------111----1---------- --------11-----------------------111-1--------------------------------------------------11-1-1-----------------------------1--------------1-----------------------------12--------1------------1-11111211131122-1111--1211---1-1---11-----------------------1--------------1------1----------------------------------------11-----1--------1---11--------3--1--11---------1--1111-211----------1-------------------------------------111-------------------------------------------21---------------------------------------------------------------------1---------1--------34-3351---------1----------------------------1-----1---2-----------------1-------------------1------------------------------------------------------------------1-1-1--1111----1-----------11111111111---------1112--------1---1---------1-----------------------------------1-11-------1--------------------1--22-------------------------------------1-------1----1- 3332461-B46211522434343343522343334322324224223421435542323443145453122423334224443543444342225332233724662447B9DFGFDB988CJ9SSBZE**Z5fLk8EAAQ9HuFCCC98J99O4C99C7AA9638484B68643-441F111127ABJ4HB2143231 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.305.1 NAP-like
[ 645] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------------------------------1-----------------------------------1------------------------------------------gZjghlNPKLHQXOvdGiO**h3fZqMNLJdMUUQLSNFDXGKcNaTWU5AAFbQ92JBED12D2------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.271.1 SOCS box-like
[ 646] --1----------------------------------------------1----1------------- --1-----------1------------------------------------------------------1-----------------------1------1-----------------------------------------------------------------111---------------------------------------1--------------1----------------------------------------------------11------------------------------------------------------------1-----------------------------------1--------------------------------------------------------------------------------------1-------------------------------------------------------------------------------------------------------------1---1-----------------------2----------------------------------1---------------------------------------1-------1--------------------------------1-----------------------------------------------------1----------------------1----------------------------------------------------------------------------------1--------------------------------------- 3235678-MA8-677556465585766562454655557574455455454556456544346446551453544444445344444546B4565A454558576836GACEGIFDICDDCFDCHIHHAd*E5FFICCDCDEDCA6BFBAFECJBDCCQ8JQ996E9E69AEDB64546v4545598BB566497B687 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- * e.40.1 Cullin homology domain
[ 647] --1----1------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------------------------------L7653345567999H97555489A3D98CBC89CE79-----------------------------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------------1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -------1--1----------------------------------------------------------------------------------------1-1------*---------------------1-----------------------------------1--------5gla*LRNWh*S*g-dLji----* -----2-----------------22------------------------------------------------------------------------------------------------------------------------------------------------------ * f.43.1 Chlorophyll a-b binding protein
[ 648] -----1-----------------1322-1-12--1--------13-21-1--------1--------- --2--1-12221-------------------------111----3211111-112-1---11221-1222-----221--3-1111113322-211---11141--1-1---------------111-1-1-21111111---3-111111-22221---1-32-11--1------------43222113124337464664666666444444666131433322222244144444444444444233434233223-3322111231--3112222331111122-----------11111111111112443324442-5132-------3-421--155422---1----11--21--2-222-3-23-1---------1-3331-121232------------2331312-22--233222222212-1---3232122333--------1----111-------------------------------1--------111111-222211--22222111-211211222312222-1-1-2116---3------------11-11---2-112---1---1----112-184111--1-------1-11111111--13--441-12-11113333333533333335354-----12------22221222224255522-222255424225322222332333324444444443433434242333213--311112212211---------1111112-3333232-22211--2111-111---1-----11--121211---1--------134454444455343--------------1114-----1--------211------11-1---1111---1-1112222211111-111 --11--3----4574344446532325333322555233333333321544333334233331111121111211111111111-131436245432222134223-283D523412111113-753315D1-312121231231233224222111111226434D9BAC--13-32111125-222251-8453354 ------------------------------------------------------11----------------------------------------------------------------------------------------------------------------------- * d.114.1 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
[ 649] ------2223333242----1---2---1--------------1------------------------ 315--13233321211122-21--1122222-111122221---212--11-233-12--1111313-1-133335342211221111--11-1------1-12--4-11-------------------------22221----112211112211111111111244311111111111112221112-2115555565546667854233315571--21112111114413333333333333333334334312323334533125343631112222-11111111111111111111111111111122111222221---222222212111---111111111--112212121211---11111-B5441111-1112231111111122222222223-11111121141-54434435446411321242323323311111111-2221121-------------------------1----13111-1---1111111------3-1111-1111--------2--1------2----------1111111------1---111211111111111111111111121------1111-1----------------221122--2-1-111122211112132121----1--------31331123332333333-324343333433333333322232221332323233343233443323333--1--------------------11-1--111--------------1------11----11111111-1111-231----------1--3-----1----2244444333------1---11------------2----2-1-1--------1-------12-111211225-- ----212-7421--24446522294762232232222222222222533646875545223421311411123-21111211112221322442221221312-3--3T89755444-1--1-11-1515E31212-1----111--1-1-114131-521146334437223351552P24223589A4741344112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.70.1 Nucleoside hydrolase
[ 650] -------------------------------------------------------------------- 3322322222222222211-12111212111121112223222231222222222212222222222223232222222222222223332323332--23322333132222222222222232222222222233333---3222222222222223222222322222222222222222222233232222424244234422332222243332233342222222222222222222222232232222222232222222222222222222222222222222222222222222222222222222222222224433222222222222222222222223222233322244222212222221222222222222222222222222222222222-111112122222222222222122222222232222222222222222221222222------112222222222222222222222222222221111112111111221111111121112222221332222222222222223222222322222222222322222222-3222221322222222321121211111211111111121111112222222222222222332222322223222-22222-2-21222222222222222222-22222222222222222222222222222222222222222222222222222222222222222232222222333323222222222222222223112212211122222222223222222223323223232222222222222222221211222222232222211112222222222--------------------------24211222222224 ----------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------1129111114111-12--1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.98.1 MurE/MurF N-terminal domain
[ 651] 11111111111111111121111111111211111111111111121111112111111111111211 2321311111111111111-1111111111111111111111121111111112111111112111112211-112112121111111111111111-1111121111112222221111111211111111111111121111122212222222121121212222221111111111221111111211211111111111111122111111111112112222222111111111111111111111222211222222211222212122222222222222222222222222222222222222222222222211111111111111112111111212112112222111122121111121111211122111212321121113111111111112122222221131211122112222212222212212212211111111222212121112111111112112222222222111121121-11111322223222222212222222221222211222222111112132211221222222222111211112122222222222222222222111112221222222222211121111112121221112111111222222223222222222221-2212211111121121222221222222-22222222222222222223222211122222222222222222222222221222222222222111111111111112211111111111111221222232211211111122222222222222111111112222111111222212222122222111112211111112221211111111111-111111111111111111112121111121111 1111221-41111111111-111111111-1211111111-111211111111111121211111211-2111211111111111111112112112121111322123153332532221223234224E313233222232221332122123322122243222322222123322I222-233441422223322 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.203.1 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
[ 652] ----1---1---111---------------------------------1-1----------------- -12-4--------------------------------1221--132-1----111--1--311-2113111-------------------------2---2123111-2-----------------1-1----------1---1--11-----111---------1--12------------212-----1--3333321212232231-11--322--2-1121-----11-------------------1-1-------1----------------------------------------------------------------------------2---------1------11--1------------3--1111-----1-211-------1--------------1-1----1-1---1------------1-22-----11--------------1------------1-1---1111-11----1-2111-111112112321111111111222112211231--113-11-1311-21----1-----------------2--1---------------1--1-11-132--------------1-----------------1----11-212121--111121111-1---1-----------------11-----1--1---1---1-1-1---------12-2-----------------1--11--1-----------------11-11111-1--1-----------------------1---1-2211-2-2-------11----------1-------------1121111111--11---411------------------------------------------------------ ----24C-633n44444G4C67586AC2456345539455432544765CA8FDAC788AAA1112-3111-22111121111111-11555497C2112235525-9g2HB5B8DE7BB9C46FFDB8Ce71C7A9BBCA69D8ABBE76B9DDCC6A7GB8EBC5D78B46B52PC1N223B2833B72241368JH --------------------------------------------------------------------------------------------------------------------------------------------------------------------------A1--- * a.266.1 Indolic compounds 2,3-dioxygenase-like
[ 653] 113-1-2322223323--2111112---1--------------------------------1------ 13914---------1--11-12--5711111333331369221311---11-2121----1-B-3495551-------1---3---1-------------1-245-5----------------------------22211----5-11111---------------1-2--------------22-------1-----1---------12---1----21-----------1--------------------1---------------------------------11-----------------------------------53-24444344434-4------31-21-112-311332-213-------4--4232-----24FGH41337495111111111-1-A9E88CAD562-62251284328C7523-66144445564444444463331521------------------------------2351-45445ABBBBA22221BBCC22221285GCAD5-2665433118251A2132-1111-----------2221-3-4111121111--1113111311-133-4-------------------------222--4112-4-112222232111111--1-1----1---------1--2--3332322132-3333212323322332331------------------------51--1112----------------------------1321---------------1111111-214166663284464553433---------1---3----------1122222----------2--------------11---------------------------2222-----13-- ----211-----11-21222121121222232211111111112222211112222111111-----------1-------------1---11-------1-1----263F23223822222426E252362-32422224326232222B1292623426N2874B6AD8B356-13-8---2344672761122212 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.56.1 CO dehydrogenase ISP C-domain like
[ 654] 111222212222222222111211--------222-------------22222222222222222-22 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111211111121111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111122111111111111112222222222211121121121111221111111111111111111111112222222212221112221222221111211111212211211112111111111111111111111111111111111111111111111111111121111111111111111111211111212121111111-11211111111111111111111111111111111111111111112111112111111111111111111111121111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111221222121111111111111111111111111111111111111111111111111111111-111111111111111111111111212221111 44--453-5--1233233323333233333333333333333333333232332333333332222222222222222222222222233313332323323345513444764443435144394384GP7-B4F3433734542326246474434443344342445533433444L4444567543852144432 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.84.4 Ribosomal L27 protein-like
[ 655] --------------------------------------------------1----------------- 3331------------------------------------1---1---1--1-1--------1-111----------1-----33333-------------------3------------------------------------3-------------------1------------------------1232222222222222222322212222333222222222243---------------1--------------------------------------------------------------------------33433333433443433333---333--23332333333332333332--53333333----337593345844822222222223-6676736733333333433444334-3333336666333--------1333-466--------------------------------333332433444733333333543336364343333--533333333--364333333363-------333-33344-4344458446533323333333-3--3-4546-4445565555555555554---36-344333333633383633363366663---333332-33363333333333333333-3633633233336333333---3333333333333333333333321223233356666666664---------3333--835-------------------------3333333333633433544---------3344633333663333333333336------333333443333333333--------------------------4-43344244-3-- 1-----------11----1-1-211-1---------2212222------1---1-----311----1---11---11111-------11--1-12-1------------11--21---------21-1-281-111----1----------1-5----1-2---1---------1----------1--3-----311-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.152.1 Flagellar hook protein flgE
[ 656] -------------------------------------------------------------------- --1-------------------------------------------------1----------------------111----------****-t11---Lg2J7*2*6*------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--1-------------1---------------------------------------------1-1--------------------------------------------------------11---2111361111331--1111-3443211131214--22------2------------1--------------1---------------------------11--1--------------------------22---------1222332223333222311----1--------E71146B8FFCBCCA9A-A99FB98DBDB9CA98BB7CAA2359CC65BDCEDDECAD8BB93445564--667678748777--------------121-------1---1----33332-4-11--45442445134442344-------------2111112111-421-------1111------------------------------------------------------1----9 -----------------1----------------------------------------------------1------------------------2-----------1-----------------------------1--------1-----------1-------1------1--------------------1---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.4.6 Tsx-like channel
[ 657] 11----1111121211-11111----1---2-1-1--------------------------1112--- 122-122144321212222-211124222222-----35621232121-22-544222--3341123211-111111111115-----3333-222---111111-1-1-111111-------1--------------------11-------------------1----------------11111--11133333322223233222233332331113211122221111111111111111112111121--11---1111111121--1-11111111111--1111111111111111111111111112111111-22122222222121-222122221-11-11--11112-2222112--1-1-23111-1111-1222--112111-111-111114-11411614561-4225321531233223121311591151111111131111-11-----------------------------1-12114HHA844443433333338A55451594H34652212411322313339122--1-411111-11112---12--2212213111-----1-1------11-1--2--122212111111111--1----431111123222111112211112122233--12111------52434214444443444-4434454444444343443242473235544555555555545333333331-211111111111---2222222222-1232111-111111----111111--2212-44444555144462311111112111-222422232322232211111111-------1--------------1---------------------------1-211-1---1-11 ----111-1--21312331322256671123222121221312211443365363413122211-11-1123--1111112----1---49332341-11272222--2-2234342221-112111-125112121111321212111111-325434121-32------1-2---118111-1---333--1----- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * e.44.1 2-methylcitrate dehydratase PrpD
[ 658] ----------------------1--------------------------------------------- -1-------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------1--------11111----1-1---------11-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------111--1--1--1--------------------------------------------------------------------------------------------111----------11-1-------------------------------------1------------------------------------------------------------------------------11------------------------------------------------1111--1------------------------------------------------------------1111----11-------------------------------------------------------------------------- 1113767-A4335553443444544444444444445555545444654444444444444453344413444335525642333387647B4665665535578A15C5BSOLZLKFEDCFFBYQCPEm*I6OFhAFECIEFHC7FEEBIA7UFECFE8ACC7485B56M69A52343S3432475484875556553 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.118.3 Sec7 domain
[ 659] -------------------1-1--------1-2-------------1----1---1----1---1--- 135-3-24666--112211-14---511111-444734D9--1211---21-454211--123-735941------------4--1--112---------1-11111-2--------------1-------122-93312---3-2-1---------1--1----1-1-1-------1----43-11-----------1----1-111--11-1-------1--------2--55525523555555-21--1-------------------------1-1---------------------------------------------11111111114--33----1----2-----------1-------2-2-9244------127651--12112221221112-2-1-3--6--32--53335346653445--1523-1--333--------2----1-111111111--1111221111111111111--28---11156556777444366645554246655DAA--44321-11437171-111-121-1111111--2-1-13----1-111--1--31-1-1----1239-1---1--------------------------1-33-1211222221422212132123--22--1------11---1-2112223222-1222222222122222226444-13412111-1111111111-311----1--111111111111---1-----334311421----1--1111-1113333334-1-3E75775776476763333---------1---3-----3212142334332221-1---1---------------2--------1--------------1------------1-2-- -1--8A-----1---4365C672EDD83423342422333322333854767B855566435-13--1-12--12-1----22212---44333821-1-353-2---23C2243522223131312213E1-315111141124211-122-531121232582-1C41911-4-11--------1176112455FG1 ------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------ * b.3.6 Aromatic compound dioxygenase
[ 660] --------------------------------------11---------------------------- --------------1---------------------------1----------------------------------------------------------------------------------------------------------11---------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -1----1--------------------------------------1--------------------------------------------------------------1-*EPVRXVLEPFPSKofHbL**o1bUpKNLHWGOeMAVGECiFGqIUNE9654-8I44644-8BEA----------------1------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.41 SEA domain
[ 661] --------------------------------------------------------1----------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111---------------------------------------------------------------- 6434995-C33577754434444454344444445444243444444345445433544555535444155455555-4545555545548445554444454999266F8LGIPIQDEECDDDXLEUCi*J3UFZDEDCICEPFCFFB9NDBeEMEDD58a75586J55M6E642232F11113933H4C8227CBC4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.62.1 Pepsin inhibitor-3
[ 662] 11--11-----------------1-------------------------1---62222211------- 2231222222222222222-22113222222323332222222222222221222222--22222222222-1111112222111111111212111--111111112111111111112222122222222222111111111122222222222222222222122222222222222222222232122233333333233333322222233322222222222222222222222222222222222222222222222222222222212322222222222222222222222222222222222232222222222222222222222222222222222222221222322222222232122221222222222222222222222222222222222-11211222222222222222222223222221222222222222222222222331111111111111111111111111111112222211111222222222222222212222222232222222222222222211123232222222222222222122222222222222222222222222222221111122222111111111111111222222222222222222222222222222221-2222211111122222222222222122-22222222222222222222222222222222222222222232222222221222222222222112222222233222222222212222212222222222222222222222222222222222222122122222222222222222222222222222221211111111111111111111122-1121111111-2111111112122212221221 -1--1---1---12---11-11-1-1--------------------------2-111-----1-1----------1-----------------1-1-----4--1-1-2-------1-11----------1----------1---1-1--1-------------1-1-------11-1-----1-2222122-311--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.79.1 NusB-like
[ 663] 11---1-1111111112-12112111111311--111------1--3-----------1-----3--- 1121232222222222222-2222232222222222222221212222211123222211212212122121222222113111112122-2-----------1---1-244344433422221-----1-----1111111122121122211111111112211---11111111111111331111-22222111222222122223221312123232222222222222222222222222222322212122131212222222221112223444344333333333333334443444444444333332333311122221222232313112333211322111-1111111-1-1221-22--2111122222-11112221211122222222222-11111111211122222211222111111112111112111111111111113111111111111-------------------1111121111122222222222222222222222211112221121222112222111133111111111111111111111-----1----1111211111122111-1111211111111111111111111112222322222222222222222222222221-1121311-11133232333333333333-3333333333333333333333333333333333333233333333333332133343334433311212222211111223222222222221122211111122224222222222222222222---------2222222222223222222222222222221-1---------1--1-32111111---11-11111-11111---11112-2111211- ----1-----1-1-----1----111--------2-------------1--2-112-------1----1--122-------1-1---------11-------------42311---4231121423321AW41733332252121121-3231132423-------1----1-------1--3--11-----11--1-1 ---1-1-1--------1--1-1-11-----------11-1--------------------------------------------------------------------------------------1---------------------------------1---1-----11-1- * a.98.1 R1 subunit of ribonucleotide reductase, N-terminal domain
[ 664] 33333333333333333444444343333334333333333331121133333344443331113233 1111111111111111111-111111111111111111111111111121111111111111111111111111111111111111111211211111111111111121111111111111111111111111111111112111221111111122221111112221111111111111121111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111122111111111111111111111111111111111111112111111112111111111111111111111111111111111111111111111112111111111111111111111111121221111111111112211111111122221111111111211111111111111111111111111111111111222111111111111211111111111111112211111111111122111111111211111111311212211111111111111111111111112111111111111111121121111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111222111111221211111111111111111111112111111111111111111-111112222221111111111111111111112 11111111513123244342322222222222222222222222223234334344433333323222-3222223332332223233326242232222233457115154643141-32222782417W31434121171251-121131132322224224231414244222221Q1111195A72731111113 --------------------------------------------------------------------------------------------------------------------1---1------------------------------------------------------ * d.77.1 RL5-like
[ 665] --------1-1-11--1-------11111-2-----------------------211-11----1--- 145-----------11111-11--211111111-----11-----1---1---------------21--1-------------1-------1---------2-1--2--------------------------1----------1-------------------12------------------1-------1111111111111111-111-1111-------------1--------------------------------------------------1---------------------------------------------------------------1----------------1---------2-11223-----------------------------------1--------------------11-----------------------------------------------------------2-------------------------------------------------------------------------2-1---11--1----1--1-1----2112---------------------------------1--11---1111211133111212112---------------------------------------------------------------------------------------------------------------------------------------------1111--1------1------------------------1----32122212------2-11-----------------------------------------------------1 ------5---1-43266994444747545554555545554553443433777786A4444446434424333354424423334322224369314342243EAC-43-RLLEIIHD8EABBDOD9NDq*N1OFP8EABFCDFE9FA96D99LHDCDFDBJ4A662535257F71122C32315C76G8HE44CBCF1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.8.4 PA domain
[ 666] 11111111111111111111111111111111111111111111111112111111111111111111 1111111111111111111-11111111111111111111111111111111-111111111111111111111111111111111111112121111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111-11111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211211111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111211 11111121422122223222422223232122223422222222322223332222243122222222122122213111222211443231322222222334461231445557713553646E4S5F*B-8GP6231E44595633192394444221424321423-22223222J1111284G62421221112 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.23.15 Ribosomal protein S2
[ 667] ---1--1111111111-1111111111111111111111111121111121111-1-111-113-111 112-211111-11112222-22111222222122221244-31111211231122123111122112222-1222122111121111122221211-1111212112111111111---1111-11111112111-----111--2-22-11---------1--1----1------------111--1--111111112222211321111122222111211111111112111111111111111111111--1--1---112----1--11111111111111221111111111111111111111111112221111-1-21-------1-1111111111---1112-111111----------112-13222-1111111111121111111111111111-11311311112-1111112121223122331322221332222222211111112-----------------------------1222112111323333232222222433332332211111122211222122121211111222222222211211212241122213112-223222225--1-2221111112212211111111112112222222211213212323222232222222223--1111121111123333333333333333-3333333333333333332223333423433333333333333432433332-22233333333321131121111-12121122222213333222233333311121133333433222321332222222222122222222222233112222222222222111111111----------1------------------------------1-1111111 2--1--1-4-3-1-2222142232233113212333121332111212222-2-1-211223121221-1211111112121112111142-22431122232134-141541312-1--12-21--5-5B4-13412-131-3---1-1-122--1-y1-6--1-21-111-4-1221E11111B5741331222132 -1---------------------------------------------------------------------------------------------------1------------------------------------------------------------------------- * a.130.1 Chorismate mutase II
[ 668] 11111-11111111111111111111111111112111111111111111111111111111111111 1121111111111111122-22111122222111111111111111111111111111111111111111111111111111111111111111111-1111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111222111111111111111111111111111111111111111112111111111111111111111111111111111111111111111-11111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111-111111111111111111111111111111111111111111111111111111111111111111111111111111211111-1111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111-111111111111111111111111111111111 2211223193333334434233243333333334233323333222333333333432333333333333333332313333333223345243433333363437137465744532223443492C28V5-5692443633542334432344322425443431334623332333R3343376663673332324 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.62 Ribosomal protein L10-like
[ 669] --------1111111----------12------------------------------1---------- -11-----------------------------------------------------------1-1------1-------------111---------------------------------------------------1-----111-221--11------1---11-----------------------1----------------11------1-------111111----------------------1-111121-1-111111--1111-----------11---------------------------111--------------------------------------------------------1---------11111---21111--------------1--1---1--------1---11-11---------1-------------1-111-----------------------------------------11-1-------------------111--1---1------------21-1-1-11-----112-111-1---------------------------------------11111111111--11--112--1----2----------------------1---------1----1----------------------------------11----1--------------1----------------------------------1-1-------1--------1-----------1--------1---1-------------111111111112-11--11111------------------------------------------------------------------- 111--1--311-111-221----1113111---2321111111---1111333433211221-----1-1----------------------2--A-----1-----141OJXUYXSFGFEEHHSPGPEj*O-TQXEHGGQHGLIEFDGDMGCQGHKINAADOFIQDGDFj6A8823414---435A9819L65EEBE2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.74.1 Carbonic anhydrase
[ 670] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -----1--1------1---1121111-------1---------------------------------------------------------------------1------*6I356111111-2321419L3-4342221312421-21--12915133ZgI9********VRS--11-----1---1----1M----- ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--- * g.31.1 Invertebrate chitin-binding proteins
[ 671] 11----1-1---23-2-------422231411-1--4-12-1122-66--655---262--------- 556112---1-1-----33-31----32333--2-1--14-342---24--1111211--111----12---1112--1-61--1---31--22-----7312--191---------------4--6758-2E1111115-1--18J8387W--111-----331A6762-------------1--1-------------------------------2---2----------222122222122122---1212-12--23111--13-2-------11-111112133332322243111111221111--23---444-12---------------11-------11113-27C7-172--21221-3B-124671-78-9431143122G43411111111112-46245272-34-46662544863654-13312-11----22222222445--188------------2344-1942-22-6-32--131-1----3332221------1111----4211233--35211-31321216--72--1-2-1-----H336111346--51-622221263441D2A1111--421412--1-13-1-22422145-12446-23432-522--31121--1-11-3--11---3832A------45121733422333732-1233223323441113224312648H111213321411231127-123113--51112111-21---713313321-21-125-1-1---2232625---2-21112-761111122313121-671-----1----5-348696722132--234224445434--632111----------7-1--------------------------2---------1-- ---------------------------2211---------1-------11--------1------------------------------321-111------1-----2----1--11------------------------11------1------------1-1----------1---------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------1-1---------------------- * d.298.1 RelE-like
[ 672] ------------------------------1-----------------1-1151-------------- 3318337677777955555-565565555555666669798B8F6882778898864A7777849A9AA98666634444754-----221322224--2312344334---------------7346644335422245---33-------------------------------------333332236667777787767778876666667775666545555555685555552555555555555575546543535345555523445444444554544433333333333555555555555557744477755555855555555554333688945435733545545555454555523421-3-----------------------------------------------------------------------------------------------------------------------------------------------------------------2----1---------------------------13-31-1111111111111411111111111---------------------------------2-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------33333333332342322--------------------------2132233323---3 -------------------------------------------------1-------------------------------------------------------------------------------------------------------------------------------------1--------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.11.1 Penicillin-binding protein 2x (pbp-2x), c-terminal domain
[ 673] -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------2--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-----1111111122112211112--11111111111--1-112231112211111-----------------------1121-111222-2211132315--GOQKPGbGGNGJRI*jGfH**c2iN*GJEEkAIyXHJFIGWEFmGMGII57GK9674C67I446D----B-13----1-1---1--11- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.20.1 Blood coagulation inhibitor (disintegrin)
[ 674] -------------------------------------------------------------------- --1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------111111-1-111111------111------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2212119-H789AA8---121111111------1111111111---11111111111-11111-111-----1-1-1-11------1-1111-1111112-1111--18AV8C9CANCA66DEBKN9IAe*E7JAO9DBBG9DD78CFB9PAAeCKFFFIs*IGF59ECC*11GC-ADC*23242911-11812CGDFD ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.140.6 PRP4-like
[ 675] 22-1-266666666661332244A122111215422324444423222365642---3--33234--- 2256622----11111111-121112111111222212332211--12-----1-11---11112352221---------1322322311111111---12111322-3---------------4433312233244487---152242222121111111122222222-1-----1----33333---4344444433434343346544433343452312------321-------------------1---22-------1122-1----111--------------------------------------------121223333333232--11133422-1-4--64EE8B7311G91112-2-242---1-----22121111111111111111-111-33133132211-11121121111113---11211112111111111132213122-----------------------------1--1-122222544745544435567444434666454422334342222243332235122222222222222444-BE788855967771DAD4C6C354434127D21-214444332222222222341155211-2-2--1211111-111111111111----2328------2-3221-3222323233-233333333323333233111121--3111111111111111111212222--111111111111-------------3-2212222122111-2222-------11-2-22222331222232122----------12231111111-22--------------1131111111--------2---------------------------1-1-11111122-1 -------------1----1-------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.349.1 CPE0013-like
[ 676] ------1------------------------------------------1------------------ 21425-------11-1111-12--12111111222222231131---------2112---211-11332-2-------345531-1--1----------1413331311---------------222224222131111-11-2121132212212------111322411-----------43211221313666665552644554544453464431637245545447322222222222221422341152--23---44--21211221122--3----1--11111111111-------------121111211-11146454556515133112222235111133144322112322213-1-3135223-1111531-12211211222222222224-2331332234514773555666442412143635344251111111123323645--11122211112122-2211-22-----113532222244345442555433335455445433365122232233233332234232222111111112233222111-225353445-4742444422232322142211111111---------2112-22333222121222222222232222222222--13343------22232342222222222-2222222222222222222343223322222222223222222422222221-222222222222---22221222223132211111111111211133333221221233332211112121211211111111322221111122322111222211111111132--1111--------2--------------------1-------1211212221211 ----1--------------1-----------------------11--------------------1----------1-11-------------------------1---------------------------------------------------------1------2--------1--------------1--1- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.49.1 C-terminal domain of B transposition protein
[ 677] ------11------1---------21113111211---1111-21111-1111-----1--1----11 132-111111111111111-11111211111111211111121111111111121111--11111111111-11111111111----11111-111---1213241242--------------111111111111111111112-222211211222222221212223122222222222211111--111122222222222222222111122221132331111121633333323333333333333112133321-133112211111222211122222112222222222222222222222222112221111-11132222222-2--111-111111111----221----1------1221-22222-----233222122222211111111111-22122133222-2111223222331323122111112221111111113311111-----------------------------122251111122222222111122421111112231213-11111111121212112221111-111111111221111212112111111211122121111212112111111111111111111111-11211222221522433322223262222222223--12211------11111111111111111-111111111111111111111121111111111111111111111111111--111111111111---211111223212122111-1--1111111111111112321211211233111111111222122222122222222243333221111111111111111221122--------111----1-1111-11---11111-1111-11------1111 ----111-42111111111212111111111111111111211111112111111121-1--31211111111121111112221111111111111111111222-2N23242544222221233251BO3-72822212222212211521512223211151114221-1222458f67744534616AA64222C ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.28 Peptide methionine sulfoxide reductase
[ 678] 33333334233333332333322131122321232211-11111112221331121222221332332 21111222222221-1111-1-22111111111---22211222-3323-1211211132322212122122222433-2322322221121-1121132221221122-111112-------11121111111-211221-11221111121---11111111-1111121212-2112-123133221-1122222222122222211111122212121111111112-1111111111111111111112121121121221122111221111111----1--11111111111--111--------1--111----1--1122222221211-111-1--211-1-2121211-1111111111112132221111--1-1111121121111111111111---3--111111--11212-211--11-112-2-1-11121111111111-122212222222222232122222223222222212-21-1---1------11111----1111-------1---------11------21-1---11111111111-1--121111111121111113113111121231211111111111112-11-1--2112-111111111111-1-------111--1-1-11111--111121111---1--1---1---1---111---1-1--1--1--11-1---111111111111111111-11-1111111111111111112111-----------11111-1---1-------111211-111-1-----------------1111111111---1----------1-1-1-111111-11121221121----11---1121221-111112111111211122111111111212-12 4222232-62122113222123114222232332531232322222332343422324265622232212333423413422123234325222231122233222-153726433A4443424253347M223555255427734324325354553646E14324324931242213N2212336A52232392531 ------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------ * b.51.1 ValRS/IleRS/LeuRS editing domain
[ 679] 11---13333333333-21-21113222122-------------1-----2231------11221-11 3482312111211122311-111111111111111111112223111211111111111111211112431----1---231321121--23-2-----1------1-----------------3313322233212221---1-221211111111111111113223111111111111111111---1111111112111221122111111122121211------111-------------------21-----------------------------1-----------------------------------------1----------------------1-4-12-77-113--31-------14-1111-1--1243123121112233323333332145355344341-111113333322341112121111222333333332442-5111112211112111111111111111111112243142222333343322222253222213435323323233221222226213232-11221111111122225-11362122-3113-6564545-25545114253433335434242222222371222221-221221114576613B88746786464---1422------313223-3333333333-333333333333333333323211412233333333322323323333332--111111111111---1-----11113121-121112111111--1--1----1112122222221122323111---------12333222223333233111111112222112---111-------------------1---------------------------131- -3------2-----2--222------132----112--------12131--11123311--12-321---2-12--4---2---1--11-11-312211-2-1-111-11--25413-1---1-21-3-4E1-12-----2-14211-----12-411---141-11213*153-212---11-1222E132-1131-- -------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------- * f.21.1 Transmembrane di-heme cytochromes
[ 680] 224242555555555552322212---1---1322222222222222222322266776652222--2 24724-1-------22222-24--22223232222223322222----------------632--1-2322------------22-22-161-2--------22--4----------------1----------------2221-46666644444322222744977632222222222222-12-662---------1---------2----------2-2-1----1--------11--11----------1--1----------------------1-------------1------------------21---2-1---242-2-----2-2-2---2222---2---22222222-622--3-4--921244222222--2222322222222222222222-1-------232-222322322232--222222222222222222222222221222222222222---------------22222-2222222222223426444433424444224252222222222532232222222222224222222222222224--1-----------2222223--333352---------------------------224422--225222222222222222222222--2-22422-22222223222222222222-2222222222222222222222442222222222222222222222222221-233323323233221222222222242-2-22222222121322211111-1--44-44445555464654444----------232422222444445555555222222222-2222222--------6122222--------------1------24222242222--- ------1-411----1121-----1-1-----11-1----------121122-321--111--------1------1-----------1-3-1--1-1----1-3--1--31111-1-1----223-1-121---5-1--21-3---1111113----2-1-13-225-1-3231--1-1-1-112111--3-13-1-- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.283.1 Putative modulator of DNA gyrase, PmbA/TldD
[ 681] ------------------------2---2-24------1----------------------------- -----11-11111-31411-12--1311111141113332-1-12---122-1--1-1--24--3-2222--------2--2111-1----1------------2-11---------------------------32111---3-DD53445332233432322237534335333343433331------21333333332323332233311332---1322------22233333333333333333311-------------------------------------------------------------------------211111111111-11111111----11--111--11--------112-21111-22-2343552225324344444444444-5454444423--55556638775554---21522441322222222211133212-------------------------------11--35422433544333335573333333533354211223121115211322141211211111111---12------11111111--------1------11-2---------1-1-1111111-------111--11-1---1111-1-1111-1--1------1--------21111111112122211-11-111111112111111111411--1111111111111111111111111----------------------------1112-------------------------31223235452334314441111111113------------2-11111111111111-13111---------------------------------------------------1-- 11-1224-311-11221211222222211222221221-1111111--221222222111-1222132111121111-111-111131112111112221121231-2c62-222232-1121245151Wk8-A322121222322221-321413222---1-31----3---22BA6*754955324222476755B ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.237.1 Hypothetical protein YjiA, C-terminal domain
[ 682] ------1----------------------------1-------------------------------- --------------------------------------------------------------------------------------------------------------111111-----------------------------------------11--------1-----------------------------------------------------------------------------------------------------------------------------------------------------------1-1--------------------------------------------1-----11--------1---1-------------------------------------------------1----1----------------------------------------------------------------------------------------11---1-----------------------------------------------------------1-------------------------------------------------------1-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11------------------------------------------------------ 5523845-B33-7564434444545554455554545434433444454544443452444444444414434445554544445455535344333333334667-564GJTEIBQC9B8EEDMP9RBe*K3LFY9BABK9DJE6DC77GB6PCDABC49R85676C55H47753444*43344E5DA5A55944446 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.1.10 Clathrin adaptor appendage domain
[ 683] ---------------------------------------------------1---------------- --1-------------------------------------------------------------------------------------2321-1------31311----8887778EHIIIMM----12---1-1-----------1----------2-1-1-----1--11----1-1--1---11--2------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------88--12--15HA6H1-66842-7484312-31-313-9---2----3545-1443-1-41-23C41-5-12-1---2---------3321-11-----------64557945B424554----3321138JHE4434444-2222441-3333145522513-1-22-------1-3-2F--2-33235454461-2-11---1C---161122I-------2-------2--11222-125-214444244-11--1------1---1-111111211111-11-111-------------47--49-6DCC88AAB8-9879A4967C98B787875-1-33115674534634662625466558633--5BECEDD8BDDB--7------12111-3--222-2-231115113-------1-1--45549692245441948----------1--1----------AA556555665545--1-------------------------------------------1----------1A2 ----------1------1-------------------1-------1------------------------1-----------------1-----------------------------1--------2--3---1-----11----1------------1---2---1--------------------1--1--5---- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * f.4.5 Autotransporter
[ 684] -------1------------------1211111-1--------1------1----------1------ ---1----------41111-1-1121111111-112311-11111---------------112-211112-111111---1-----------------------1--1---------------------------------------------------1-----1---------------1--------1------------------1--------11--------------------------------------------------------------------------------------------------------------------------------------2-----1--11--1-------1------------------111-------------------------11-1--111-1---1-11-111111---------1-------------------------------------1--------------------------------------------------1----1---------------1--12-12-----1-----2111--11-----13-2------------------------------12------------2--------1--------1-------------------------------------------------------------------------------------------------------122-----------------1111112222---------------1----------------------111--2111211111---------------------------------------------------------------- 111-111-421-11122212222232322111122232222222221222222211222222112111111121111111111111111121211-1111111121-242FZaQSYIBGDFFHFsdCT8**J-eJmBCBBJBGIEBEBFCI8BXCGCEI58DE9A52T9AD57A6121281--2222422113121111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.194.1 L27 domain
[ 685] --------------------------------------11111------------------------- 1111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111222222221-1211121121111111111111111111111111111222221112111111111111111111111211111111111111111111121112111111111111111122111111111111111111111211111111111111111111122311312222222111221111111111111111111111111111111111111111111111111111122111111121212221222111221221122111111111112122111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211121111111111111111111111111111111111111111111111111111111112122111111111222111121221221-1111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111112111111111111111111111111112221211111111112-122111111112111111111111212321111 21--111-412-312126242222-3222343322-2--22-22-2332223332-332323D22333232541223223334324-121312E6Y4332213112-18245634422233233562517M3156733323233-333114425322331211324262312922-342I22321P37F453315BKB1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.100.1 L9 N-domain-like
[ 686] 221112222222212211111112-11111-2111333455921111--12112122242211111-- --------111-----1----1--1------11----------1---------1--------1------------------------------1-----------1---1111111----------------------11-----------1--------------------1------------------------------------1--------1-1-----------------------------------11--------------1---------------------------------------------------------------------111----1----------------------1-1111--------1---1--------1-----111--1---111-1---1----------11---1---------11111111111------------------------------1------1--1---1-------------1------------------------112---1--1-1-1--------1----------121--1--21-------------11-------------------------------1-1------------------------------1-------------------------------------------------3-1-----------------------------------------------11---1111-------11-1--------------2-11111112111111111-----------1------------1-11111111----------------------1-------------------------------1-1------- 64342542G63654665334444334455444433364343456563365556565443454644543264454443243532444534474535645545545592578FCG7HE79893879II8HAT*D3MBQ77978889569857D87HADB8877C37533D55978865578w5287666A844A5754763 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.17.6 Pre-PUA domain
[ 687] -----------------------1111111111--111111111111111111-11111111111-11 112-111-11111-11111-111111111111111111111-111---111--111-1--111-1111111----11111-1-11111----------------11-----------------111111111-1111111---21111111111111111111111111211111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-22-1-111111111-11-11-----------11111-11111------------------------111--1111111---------------11111111-------------------------------------------1---111111111111--1111111111111111111-11------1--1111111--1111111111-1111-1-----------112121111111111---------------------------11---1-2---------------------------1111--------------------------------------------------------------------------------------------1111111111111-----------------111111----1311111111111111111------------------------12111112222222-------------------------1-11111121111111111111111111111-1-- 43445231C4445334345544445445544444544444444555453455264444343345444514544534514455564544445434674454444455567567978876565476884D3Gh9297D7465656765656685594F5665CU354445648H7614454V4445546474814357573 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.215.1 Smc hinge domain
[ 688] -------------------------------------------------------------------- --1-22221121-121122-22--1322222122324112132111--1-------22----21313B891----11211-22-----11A5-8112---22113---1----------------1-------1-76666---823--3--1--22212122--11111--1-----2----1--------127685866756669771-3315569-1-31--41112121321111122133221111242121-31--1---44--1112-1-----------1111111222122----------------------1-21--31321-22131-321321-13--3-221531-21-21-1--1-112--211121111112221131111211111111111-21111111111-111111111111211111121311211--------1---1121----------1122--22121-22-1-1111121-22222222222344442212444425322112111112113116221411111211321111111121222-32-------1---------1-------2--1--------------------1---111221311112111111131111111211122--12113------22224233223333333-2333233323233333332222221122322222222222222232322223-233333333333--211111122123132-11111131211112111111111222133432233232222432111111111121111111111111222222222211111-12223333----------6---------------------------1-----1--131 ----1-1-1--------------2-21112111----------111--1----1--1-2---------------------------1---------------1--1-11-P6522426761265792869L6-76A664525463-245674443--23----991DPGBG11-1---1-----1-----1--11---- ----1-11------11----------------------1-----------------------1-11--1-----------11---------1-1-1---1----1------1--------1---1-11-----1--------------1-----------------1-------- * d.118.1 N-acetylmuramoyl-L-alanine amidase-like
[ 689] 11111111111111111------111111111111111111111111111111111111111111111 1331111111111111111-11111111111111111111111111111111111111111111111111111111111152122212BC961E111--121116113311111111111111212222222212111111111112211111111111111111121111111111111111111111111211111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111114111111111111141111111112111111211211111112231111122111111111111114311111111111111112-21111911121112241121123111111112233211111111111111112111111111111111111111111111112211111111111111111111111111111111112111111111111111311111111111121-11111211111122121111111111111111111111122231111111111111111111111111113331111222333333333333333333331-1222111111134333333333333343-33343333333333333334333333333333333333333333333333341333433333443114222222111111122222222222221222111111111121111112211111124421111111111333322222333331111111111222211112222221111111131111111-111111111111111111112122111222211 --11211-211-1111111111211111111-1111111111111111-1111111111111111-11-1--111----1-1111111112112181111111111114131211231-1111112-21591-22311-11112--1-111--211-11--81-11121-2111121115111-132331421231111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.58.42 N-utilization substance G protein NusG, N-terminal domain
[ 690] ---------------------------------------------1---------------------- --------------------------------------------------------------------------------1--1----------------------1---------------------1-----------------1---------1---------------------------------------------------------------1----1111----------------------------------------1-----1--------------------------------------------------1------------------1-----11------------------1--------------1-----1---------------------------1----------------1-1---------------------11----------------------------------------1-------------11--------------------------------------------------------------------------------------------------------------1----------1----7-----------------------------------1--------------------------------24------------------------------------------------------1--------------11----------1-----------------------------------------------------------------11-----------------------------------------------1-- --------222-------1-2--1--1---------1111111-1-----1-2---------------1-1-------1----------17---2------------34-iecUfVVNPKHOMNggIVLl*V-aMqKLNLTMKUKBPRJGRHFaMQFGW7GJ848434587568-1---1--11--1---211--1--- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.66.1 Hemopexin-like domain
[ 691] -------------------------------------------------------------------- --1-1------------------------------------1--1-------------------------------------------11----------------1-----------------1-------------1------2--1--1--------------121----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------1----------------------------------------------------1----------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------1--------------------------------------1-------------------------------------------------------------------------1-1---------------------------------------------------------------------------------------1---------------1--------------------------------------------------------------------------------------------------- 5824D95-A333AA53837955657684366464876696546844985744734566584B454523245464635374512465366A958B988876592653175GHFF9H8C8D5C8AGLH9J9b*I1ICR99DEC8GE5E997BGFBI9ECA761C8B6A5844C7AE74587G3734298CI591-668442 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.69.10 3-carboxy-cis,cis-mucoante lactonizing enzyme
[ 692] 22----1134433331--22211231131112------------------------1----------- 1111212222211213333-32111233333122222112211112212111112111--32232121411111111113HJ2-2111------------------------------------111--11112-11111------------11-----------1----1-----------111211111122222221222222222122122223231111111111112332233232333322222111111112111111211111---11111111111111111111111111111111111111111111111133111111111111131111111111131111LI111112231111111-2-1--1--1---11--211-4---11121211112-122112121-------------1-1--1121221223221111111121111212------------------------------1111112226222212422222212333323121434412343232333334213312111221111111111624-132332211311411214212211111111114321112211-1-------23121223212212111133443159366255463B5--11621------54445526667676766-6666666666676666665665333238777778877888778555544351-244444444444--12---------1223-44443323332233411111112131222221111111113111----------3444333334433321111111111111-11-------------------------------------------1111111-11---1 -----1------21---1---1-------1---------------1-----1----------1-----------------1---1----1---124--------------1-111-2-1---111--1-11------------------------11------------1--32-------1--1----2--------1 ------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------ * a.184.1 TorD-like
[ 693] --11-11111111121--2--11111111111222111111112222312222111-11-------11 1113433222223232322-22112633233123332433111122322221645123--22324563441----1111131211111111-12-1--------2-1----------1--------1-------1222332222111211111122111111111121211111111111112111122-22333333344343333333222334332222224444452322222222222222242223221123111112211221221113132222112111111112111111211211121121222111222233223333333334222333332231331324233321221234333131-11----11111--21-11---11-2222-222-25-22122122131-311-23355233211111-1----21-1111111121111-12---11111--------1-------------1---1111112222222322222323334222221111-11112----1-2--111--322-111111111221-1-2111--31233331221221212111112212--12111111-1-------1111111111-1--11-1-------11---111-1-----1-11------32--11-1111121211--111211111-111111112221---3----------------1111111--1222222222222---11111111112-12-1112-1--------111111111-12-1222111111-1-12221--------1111211111121-----------------111111111--------1-211111-1121121---12211111121122222221-1- --1111--21--11133221111212222111111113121222112137335543232233314112-1121132212212221112212231213232211112-1-152321221221211121124G2-315211-2-2113212111-62312211-135216-2359--114181112264762442222111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.208.1 DhaL-like
[ 694] --------------------------------1----------------------------------- -------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1-------1--------------------1----1--111-1----1----------------------------------------------------------------FIG9lSPSQRWYU*dRpY**u-viwTRSUYUaiaLZYSPZTNVOUI6H---1--------------1-41-------1---------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.9.1 Interleukin 8-like chemokines
[ 695] 11----1111111111-11-111-12221221--1--------2--111-111--------111--12 111--11211111121111-1-1112111111-1111211-111112-111111111111---11121211-----------111-111111-1111--122113121211111111111111111111111121111111112121222221111----1111222231------------11111---222333333333333333322222333222111111111131122222222222222111111---11-----------1-----11111111111111111111111111111111111111111111111-1-12222222222211222111111--2---122-211-1-1--1---1211122111111213111121212212111111122-112114111111133111111111211211111111111111111111111112111111111111111111111111111111-11321122221111111111111111111111521112-111111211212131111211121-1111111111112---1-31-1-111-111-111--111112121111111111111111111112---11221111121111111111121111111111111111111-11121111212222222222-222222222222222222222211212222222222222222222222222112222222222221111111111111211211111111111111111111113111122222222212222122211111111111112222222222233232333332222---111----11111111--11112-----------------------1-------2211 2211221-D56-9B2343233333323333333222222222233322333333443433335442323333434332333444333334544333111131321211242131112111-13111111483-3131-1111211111--2111111121112311111331233367171115733863732342212 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.44.1 Fe,Mn superoxide dismutase (SOD), C-terminal domain
[ 696] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111122-2111112222211111211111111111111111111111111111111211111111111111111111111111111111111111211111111111111111112211111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111121111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111-1111111111111111111111111111-11111111111111111121111111111112111111111121111111111111111111111111111111111111111111111111111111111111111111111121112111111211111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 21112221A4313231222122222222232223221222222333222233232222122222222212222223313322222234422222222222222357126232422233331232642847f7-56C2332524343333152122232323123222332223223333e3333398B72752332232 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.21.1 Ribosomal protein L13
[ 697] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111211111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111121-111111111111111111111111111111111 32112211933122322232222222222222222222222222222222222222222211222222121322233323222222333243222222222224551232323222222A52328C2J38dC-3492223C12K23222121233532223223222626233323333a3323365783432222221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.55.1 Ribosomal protein L22
[ 698] -----11121111121--21-11-2111111-1111-11111211112-------------1-----1 163-311111111172233-32116233333322223345153421111111222112--211-31244411111111--111--1-11111-112---11111333-1--------------2--1--1---1----1111-3-3223223--121121-112-2316-------------111----1--2222222222222232113323222---1111------121--------------1------------------------------11111111111111111111111111111121111111111111---2111111111111111-1111-----1-1-1122111---------12-14221111-1424123124122112222221222-3243342411112112331121113112211112111111111111111112211-------------111-1111111-----1132111221233333343333228532333454422241111212322222121322-1124111111112--21221112-312212121323334323113123-1211111111111111111111112112111111112121111111111111111111--1111-------12121233332321233-3323322333323332332333222311111211111212112422222221-222222222222--11111114334312211-11111111111112222223111113333234211112332211111111111111111111111111333332222222113-221111----------------------------------------------13-2 --11211-311-2222334244323122244442112222222333426A535824433333111111111-12211122123211-11467382B2223231233-2432-11--1--------1----2--1-1--1-1-1-------1-------111-2212111242331-631-11133544E3C62-4336- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.53.2 beta-carbonic anhydrase, cab
[ 699] -------------------------11--1---1-14--1111----1-2--1--11-------1--- 1---1------1-1-----------1----------1--------2--1------1------1-1--1-------1-----1-1-1---311--------1-21-1111--------111111--11111--2-11--111---1---2---------------1--2---------------1-------1--------------1----------11----2------1--11111111111111--221--1111------111-2------1-------1-11----------------------------11----1-2------1-1-1----111-------31121---111----1-------2----------------------1-----------------------1--------1---1---------------21222222---1--1----------------1-------------------2-------1----------------1-11-------1--1--1-112-3--1-11---211--1111-1-1---2---1-11------11--21--1----2--1---1-2-1---2133111-1-1-22--2---------3--2-1-2-------3----211-1---------11----------1-------2--------------1--111--1-------1------1-------------1-----11----1-1------2----112----11113----------11--1-1------------1-------1----1--------1---2---2121-1-2121--11--11-1----1---1----------111-----1---3-111----1------1-- 82-172--2-2132735A54375444264344334434344443323335222723322222-------1-1-1-------111211117A65AB7222223-4421135FBD9NCP68989AAGL9JAR*E3HEQ7A89G9AE879788F98N9A68D26B765B5D8DHdY74-321E---12CJPL5EB-1556A2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.34.14 PAZ domain
[ 700] ----------1------------1---1-----------------11--1-13-----------1--- 1-2-3112111111445----2--25-----232122284121121221221232321--1-113327431---------1------1111--1------211-222-1--------------1-------------------2-11--------1---1---1---131------------113-----1-3444443241334444224223433---452211111124311111111111111221111-1--------11----1----1------------------------------------------------1------1-21-1-1-------2--1------22--1--------------21--------242213-11121-11111111113-76566365-1--2112--311122-111---131331-11111111123313-22-------------------------------14-1111133443424111122543333113242-21-1--21222223315-13112131111111112131113---121-11-1121--------1-11-3111---1-1111112222222221---1--11-2-22132-22332-1222221121223---2---------11-1-112111211111-1121111111111112111122--1111-111111111111112---11111-111111111111---1-1111-----1-2-1111---11111--144544211241-445435752333443442---------112112122221113243333333-------1--1222-----------------------------------------------114 ---14211----234457545356A644333333543222222333887889874723244432222221122113212251114112158354315341171525-352E1422452222431632313G3-664122232333321212212253673645632541194322118-11--14A5B6559216343- -------1--------------------------------------------------1-------------------1------------------------------------------------------------------------------------------------ * e.5.1 Heme-dependent catalase-like
[ 701] 11111111111111111111111111111111111111111112212111111111111111111111 2111111111111111111-1111111111111111111111111112222111111111111111112112222222112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111121111111211111111111111111222211111122122222221122222222222222221121111211212121111111111212222222222222222222222222222222222222222222222211111111111111111111111111112111111221111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111212122122222111111111111111111111111111111111111111111111111111211111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121-11111111111111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111-111111111111111111111111111111211 2211122183322222234222222212222122232212222232222232322222222232333312322332324232332333326222211222234335116131111121-11-237A-B16b7-24A121151165111-121121213112111113522212112122H11112746F3741111111 ------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------ * d.140.1 Ribosomal protein S8
[ 702] ---------------------------1---------------------------------------- 3222222222222222222-2222232222222222232222213222221124222111222211323411111211111121111111111111111231225141311111111111111121112-11111211211111211111111111111111111111111111111111112111111132222222222222223222222322221222222222222222222222222222222322222222222222222222222222222222322211222222222222222222222222222222222222232343333334332222212232223222122122222322222122212322211111222223222222222122221213122223222322-34423323332424222322212222211111111242212111111111111111111111211111111113222123312325322322223332222222242222211222234222232312222111111111111112222211311111111111212111121222222121111111111111111111111111221112321211121111112111131131121-1122111111111111111111111111-11111211111111111121111111111111111111211111111111111112112222111111111111111121212111111111-11111111111111111222222222232223321111111111111111111223232222222222111111111111111111111111222232-222222222222122222222322222221212 11---1--21--11---2--1-1-2-1--1----------211--------12312----------1----1----1-11-11------1-2---------11--2-12---2111-----1--22----1------111-----1-----2-1-1---43--1-1-4---1-----2-1---1--33S-8---3-111 --------------1-----------------------------------------------------------------1---------------------------------------------1-------------------------------1---------------- * b.42.4 STI-like
[ 703] ------------------------71122313--1-------126-28-7LCA--------------- 123-1---------223----3--21-----112224122-2-12--------43-------1-3-24541---------4-1--2--337--9--3---3-1-531A5---------------1--1412377123321--121553F11-2233---1--38-5AAE-------------22----1--1------1--1--111-1-----112-1---71-----11---------------------1-----1--1---------------1--------------------------------------------12212-------1-1-412-----12---212233-11--31-111------8966311111126675124234833333333332-FIMGF3IU261125526828D95222242-31232212---------32212569------------------------------113--111-1211-32411114334211---2-2-322--33465344-3341-31B423483-------11429B27911263395453-B2A445359--3-64431--2----------------12-----221362715294677736167775513753----225-------2---11-1-------------------------------1---1----------------1------------------------------222-2-222-------------------------1444433477A25345332---------3---1-----11-115512112222------B-33--11----------1--------------------------11---1-1--9-1 ----12--------412111-1-322-221122122211111111111---1---211111-------------------------1111--2---1-11--11------2243542-112111-3121562-1122-1-1-11111--11--213212123212127231--11----------1--12----221-1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.243.1 Colicin D/E5 nuclease domain
[ 704] 11111111111111111111111111111111111111111111111111111111111111111111 1111111111111111111-111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111131111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 22111111834122222322222222222222222212121222223222222223222222232222222322233223222222333232222222222124571243324222221F23417B1J35T7-54C452782273216A452232112222131122422223323333c33323B4392632242223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.4.7 Ribosomal protein L11, C-terminal domain
[ 705] 111111----------1------11221111111111111111--1--11111111111111111111 221121111111111-111-11111111111111112111121111111111111111221111111223111111111111311111111111111-1111111111111111111111111111111111111111111111111111131111111111111121111111111111111111122121111111212122122211111122111111121111111-11111111111111111111112111111111111111111111111111111111111111111111111111211111111111111121111111111111111111111112112111111111221122222111111222233333332222232222233333333333-3333443333311221111111113333333433333333333333333333333333333333333333333333333343532333331111111111211111111111111112111111111112111111111111111121111111121111121111121111111111111111111111121222222222222222222222222222111121111111111111111111-111121-1322111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111122222111121111111111111111111111111111211111111112111111111111111111111111111111111111111111111111121111112222222222111111-111-11111111111111122222222221111 11--111-1-1---1-21111111-11111111211111111111121-2-2-1--112---211111111122111-1222224121221122121112-111-1-2215462214221114-76-816G313261111322121221132-22334312122221122113111111I11123221315131-1113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.97.1 An anticodon-binding domain of class I aminoacyl-tRNA synthetases
[ 706] ---------------------------------------------2----111--------------- 1211322222222211111-111111111111111132211331223132223332231144212233432233333311331123221111-111111111115111111111111111111211111111111111111112122222222211111121111322221211111211111111111112222222222222222211222222222231221111113122222222222222222222122211222222222112221111112222222211222222222222222222222222222222222211323444443334222442332111112241111221111111111111111111111111212111111111122222221222-2222222211212222222222222212123333332332222222222222122223222221111333313333133111111111112222223223222222222222222222222221222222222222222332222212111111122222211111111111111122222222211113311111111111111111111112112222211111212122333332233332322322111112111111111111111111111121-111111111111111111111211212111111111111111111111111111111111111111111222212333211111111111111111112222212111112222322222222122222212222211112232321212211222222221111112111111111-11111111----1-111-111---11111111211111111111121 11--11--412-111---------------------------------1---------------------------------------1------21----1-----1513221121----11111-1-171--11------1211------11--112--1---212118--242422C222114313-371321113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.167.1 Peptide deformylase
[ 707] -----------------------------------------------------1-------------- -----------------------------------------1----------------------------------------1----------------------------------------------------111---------2----1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------11--------------------------------1--------------------------------------------------------------------------------------------------------------------------------1-----------------------1----------------------1------------11---1-------------------------------------------------------------------1-----------------------------------------------------------------------------------------------------------11111------1-1------------------------------------------------------1--------------------------------------------------------------------------------------- 1-11223-1--24353633222223222222122333212333232443333344446444443333313223243323332223244436163373334133243-313LKRPOTMFGEDCDGkRARDx*P1ULaCFFCHDGJFBHBEDHDCUFJGGJ56BA7665CA6E55664647E7413A85AD3C8-11322- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * a.4.3 ARID-like
[ 708] -----------------------1122----11111--1111122-1-1-----11----2---1-11 132-3---111---21---------2------11213-6611--3----11-121-----11--2-2341-1111111-------11111----------2---22-1-----------------1---------11132----212111111111111-1111--222111111111-111--1-1---113333333343542124213314254122212211111233-111111-1111111122111121121111112112211111111111111111111111111111111111111111111111111111---12-----------144----1-1--31-1-14141---31-11--1---2111--1---24858--15324111111111111-6533243713--411142333622423-2131----1241111111111111231------------------------------1122-132255456744222155482222-4A444A56--5562353273716243-1111221111111111-55212--12--212231111132111234411-11222-2121212-1111111-1--1--1321322-12-211112-211112122122---1--2-------112-22111-1---12-121211-2111-1121222554333311111111111111111611-1112--122222222222-------------1-6-3---211-11-1---122222221115-22325533113-3-222111111111-1113333332222212--------1-----2------1--------1------1---1--------1---------1-------1--- 31---1--42-2---24311222553222222211132123112332125234112122111---------1-----------------1524151------1122--2-A433323224154139-51AT8-45421-26344323-2143-7342355-143453--1-57222421512112263B2341152451 --------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------- * d.80.1 Tautomerase/MIF
[ 709] ------------------1---------1----------------------------1---------- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------11---------------------------------------------------------------------------------------------------------------------------1------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------1-11---------1----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1----------------------- --------1------111111-----1---------31112112112--1-235-1-111------------------------------1-1--21------1------CSVaLOHG9FBBHI**9iB***1*6*4HBAJAIGA4IEGEpA6*BBHIJA9G1I9255262351--11-----1-12431-4------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.211.2 Plakin repeat
[ 710] ------------------11111---------113--------12321-1731--------------- ----6--2223----------2---1------2-1-6432-1-222131-1-232121--23115-3132111111112-41------435--2--1--21231312-1--------------1121-22--222---111115--11-11-----------1--2-1-1-------------21----1-1299999AAA38AAA995B7746B881-162225444538B12222222222222222242122-----1--22111---1---231111----322-11---1--1--------------41111-111--664ACECADEA5C58J42-111J533-2-2-1C91-111-1------321-5122------2134411132112--1--1------11211112-2--311-22333312111-112-3232-12--------1---11-2-----------2--11--1----------11-1--11112111111-----1131------3-2-----1112--1111--211--1-1124--------------221-3113213222-23----311--1-12-2311---1-----1-------11-----34---2--1111111141-111121-1123----11-------22222213444444454-4446443444444443443454121134434434434444444524222232-333323313222-----2----11-1-1-3----1---------1--1---112-11111134121111-----2212-22121223------5244331123221111111---1441122----1---2-1------------------------------------2-- ----1---2---111--1121112111------1--1111-11----1-1--------------1----------1-----11-------1--------1-2-111--13622-112122323-34-31BA3-4331---32141-2-11-1-522121--1-311--1-112-2---1E21---1341-12--3222- ------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------ * d.60.1 Probable bacterial effector-binding domain
[ 711] -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3212221-922-56333252444433423343344334442442234455454433322454311112-2-1-2-1--111232113133343564344422524415229KKDMPPCCAABE9cZEg8**a6kOjCBABS8CKBCFFDBHC8bBHDEA254456348448347416A38564624DGO4NE2156661 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * g.26.1 Antifungal protein (AGAFP)
[ 712] ------1211112211--11112--11-----11---1------1-1-11-----------1111--- 11111111111-1111111-11111111111111111111121211-1111111111111111-111111111111111112131323111122221--111111111111111111112222111111111111222-----1122322211-22-11111122122211-22222-22221111111-2242121212222222221111222222213211111111111111111111111112-11------------------121--------------------------------------------------1-12322222222221222211132-11321111122222242111212111311112122112-1--1-1--1-11111111111-111111111111111111111111-11-1211111111111111111-2222211111222221122111111111111222222----13222222222222222222122222222222212222222333322333222322223-------112232121-221-112111222221-132-11-1211122122222212-1111111113-211221211212112222221122211212111---221--1211111-12111111111111-111111111111111111112112121111111111111111121111111-231112111122-221111111222211212----1-111---1112221222111112222--1-11-112-11111111111-1221222221222211111113232222112111----2222222222111111-121111111111211122121233222221111 --21111----13331211-11111111111111111211111122213221121121111122222211322123313322221212223-21-13131131211211257984844333133933434H3-435433153372333223126323434643232433342262-2-2I1123133851441-11121 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.65.1 Rap30/74 interaction domains
[ 713] -------------------------------------------------------------------- --------111-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------1-------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --12332-21--113-1222322212211222222232222222222211211112222211212221123211233-3321111114323212232121222563111-ScUVkdWEEDAFCHeSBVAs*M5XLkAHDCLDFMH8FFDBW79TEdIBJBSe93653Q45AFD44-111B-1--227272D2--58895 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * b.34.3 Myosin S1 fragment, N-terminal domain
[ 714] --111111111111111------11111-111111111111111111111111111111111111111 1111111111111111111-111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111131111111111211111111111111111111121111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111111111111111111111111 22111111834122222322222222222122222212122222222222222222222222322222222322233233222221333232222222222224571231324222422C114-7B-J25W7-54C4427822732269252233112222121221422222323333c33323B4392532242223 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * d.47.1 Ribosomal L11/L12e N-terminal domain
[ 715] ------1211122121--------43353324--2------------111211--------2------ 21121-11222----11----2--11-----11111111112-31----1111111-1----1-1-11221-----------1---11--------1---143324252--------------11111111112134433---1233322233333333444343323531--2122-21-2---111---1-1111111--111211-1--1-11------331111111--11111111111111-111-1-------------------211------1-----------------1111111112111---11--------11------------------1-------1---1---11---------1141222------1122--111111----------1-11221-12-2111221-1-221--2113233-3333322111111113111--21--------1--1--11-------------122-112----1111112111133111111112211111121213221111-11-112-1132111-1111----11111-1211-12111----1-1--11--11-111-------------------11-1---221441134342222213-222212--2-2----112-1-111-1121111111111111-1111111111111111111111211-111111111111111111111111111223224423222--1111-112122-1322----1----------11111-111111112121212212222323221132221221-44444543221122222222-111--1-11--11----------1---------1---111---------1-1--------1-- 3211-231522-11-444421121311------2323-1-11-1--33343333533--222-11-11----2--111112--------222421---13254113-4B3DDA98F62242323465417D314453343353334443442532965A3622569566423-F4B777j63678B69B4DB6655652 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- * c.28.1 Cryptochrome/photolyase, N-terminal domain
[ 716] -------------------------------1------------------------------------ --------------------------------------------------------------1------1----------------------------------1-----111111---------------------------------------------------------------------