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Halobacterium sp. NRC-1 (halo0)
Gene : polA2
DDBJ      :polA2        DNA polymerase type II large chain
Swiss-Prot:DP2L_HALSA   RecName: Full=DNA polymerase II large subunit;         Short=Pol II;         EC=2.7.7.7;Contains:  RecName: Full=Hsp-NRC1 polC intein;  AltName: Full=Hsp-NRC1 pol2 intein;

Homologs  Archaea  45/68 : Bacteria  0/915 : Eukaryota  0/199 : Viruses  0/175   --->[See Alignment]
b.86.1g.41.5g.50.1
:1370 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   938->1051 2cw7A PDBj 3e-04 23.7 %
:RPS:PDB   666->729 2aqcA PDBj 4e-10 27.1 %
:RPS:PDB   928->1071 2cw8A PDBj 5e-19 21.1 %
:RPS:SCOP  676->726 1fp0A1  g.50.1.2 * 1e-05 12.8 %
:RPS:SCOP  698->740 1b71A2  g.41.5.1 * 8e-05 21.1 %
:RPS:SCOP  926->1071 1dq3A1  b.86.1.2 * 4e-17 20.7 %
:HMM:SCOP  926->1122 1dq3A1 b.86.1.2 * 1.1e-24 34.4 %
:RPS:PFM   8->925 PF03833 * PolC_DP2 0.0 61.5 %
:RPS:PFM   1254->1346 PF05463 * Sclerostin 8e-04 35.1 %
:HMM:PFM   6->925 PF03833 * PolC_DP2 0 57.2 898/900  
:BLT:SWISS 1->1370 DP2L_HALSA 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAG20443.1 GT:GENE polA2 GT:PRODUCT DNA polymerase type II large chain GT:DATABASE GIB00041CH01 GT:ORG halo0 GB:ACCESSION GIB00041CH01 GB:LOCATION complement(1746166..1750278) GB:FROM 1746166 GB:TO 1750278 GB:DIRECTION - GB:GENE polA2 GB:PRODUCT DNA polymerase type II large chain GB:NOTE PolA2 GB:PROTEIN_ID AAG20443.1 GB:DB_XREF GI:10581749 GB:GENE:GENE polA2 LENGTH 1370 SQ:AASEQ MRPTDETYFETLETGLDDAFEVAEAARERGEDPTPNVEIPVAKDMADRVENILGIDGVAERVRDLDGEMSREEAALELVADFVDGRVGDYDTDAGKIEGAVRTAVALLTEGVVAAPIEGIDRVEVNDNDDGTQYVAVYYAGPIRSAGGTAQALSVLVADYARAMLGIDAFKPRDDEIERYAEEVDLYDSETGLQYSPKDAETTFITEHCPVMLDGEATGNEEVDGFRDLERIDTNSPRGGMCLVLAEGIALKAPKIQRYTRNLDEVAWPWLQDLIDGTIGADDADEDTPDAGSDSDATDEGDAPSASTDAEEPPRAAPSDKFLRDLIAGRPVFGHPSKNGGFRLRYGRARNHGNATAGVHPATMHLLDDFLATGTQIKTERPGKAAGIVPVDSIEGPTVKLANGDVRHINDPADALDVRNGVAEILDVGEYLVNYGEFVENNHELAPASYAPEWWIQDLDAAGADVQALRDSPYVDLTAPTADQAMAWATDYDAPLHPAYTYLWHDIDVEQFRALADAVADAHTDASDDDDRGVLVLDHTTTVRETLEALLVTHHQGDDTIRVDDWLPLARSLGVTESLDREWETLSEAAAEWPNAVRAVNEVAPFSVQERAPTRIGNRMGRPEKSESRDLSPAVHTLFPIGDAGGSQRDVADAARYAPDMSDTPGEIPVRVGDRVCPSCDEHTYESRCPDCGDWTDPHYECRDCGAVATPDESGRVECPNCGRDLDNVTTQVIDINDEYHGALRAVGERENAFDQLKGVKGLLSAEKTPEPMAKGVLRAKHDVTAFKDGTVRYDMTDLPVTAVTPAELDVTAGQFRELGYNQDIHGDPLEHDDQLVELRVQDVVLSDGAADHMLKTADFVDDLLTQYYGLDAFYDLDDRDDLVGELVFGMAPHTSAAVVGRVAGFTSASVGYAHPYFHAAKRRNCFHPETNVWFRDESGEWHHDPIETLVEARLDPDTADEDDFGALVQALDGDVFVPSVTEDGEETLQRVEAVSKHPAPDHLLAVETKRGRELTVTPDHSMRRWTGDGIERVDARELTAGDALPAPTQVPGDGETATSELRSESLDGTHPQRRFGDGGSVRTDEVVSVEPVRSSVDHTYSLTVAETNTLVANGLFTGQCDGDEDCVMLLMDGLINFSKSYLPDKRGGRMDAPLVMSSRIDPAEIDDEAHNIDIDREYPREFYEATRELADPEDVADLITLAESTVGTDEEYTGFGHTHATSNIHLGPSLSAYKTLGSMMDKMDAQLELARKLRSVAETDVAERVIEYHFLPDLIGNLRAFSRQETRCLDCGEKYRRMPLSGDCRECGGRVNLTVHEGSVNKYMDTAMRVATEYDCREYTKQRLEIMDRRLESVFEDDTNKQSGISDFM GT:EXON 1|1-1370:0| SW:ID DP2L_HALSA SW:DE RecName: Full=DNA polymerase II large subunit; Short=Pol II; EC=2.7.7.7;Contains: RecName: Full=Hsp-NRC1 polC intein; AltName: Full=Hsp-NRC1 pol2 intein; SW:GN Name=polC; Synonyms=polA2; OrderedLocusNames=VNG_2338G; SW:KW Autocatalytic cleavage; Complete proteome; DNA replication;DNA-binding; DNA-directed DNA polymerase; Exonuclease; Hydrolase;Multifunctional enzyme; Nuclease; Nucleotidyltransferase;Protein splicing; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1370|DP2L_HALSA|0.0|100.0|1370/1370| GO:SWS:NREP 9 GO:SWS GO:0006260|"GO:DNA replication"|DNA replication| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0003887|"GO:DNA-directed DNA polymerase activity"|DNA-directed DNA polymerase| GO:SWS GO:0004527|"GO:exonuclease activity"|Exonuclease| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0003824|"GO:catalytic activity"|Multifunctional enzyme| GO:SWS GO:0004518|"GO:nuclease activity"|Nuclease| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| SEG 514->531|aladavadahtdasdddd| SEG 871->887|ldafydlddrddlvgel| SEG 1086->1097|evvsvepvrssv| BL:PDB:NREP 1 BL:PDB:REP 938->1051|2cw7A|3e-04|23.7|114/537| RP:PDB:NREP 2 RP:PDB:REP 666->729|2aqcA|4e-10|27.1|59/63| RP:PDB:REP 928->1071|2cw8A|5e-19|21.1|142/528| RP:PFM:NREP 2 RP:PFM:REP 8->925|PF03833|0.0|61.5|879/884|PolC_DP2| RP:PFM:REP 1254->1346|PF05463|8e-04|35.1|77/193|Sclerostin| HM:PFM:NREP 1 HM:PFM:REP 6->925|PF03833|0|57.2|898/900|PolC_DP2| RP:SCP:NREP 3 RP:SCP:REP 676->726|1fp0A1|1e-05|12.8|47/70|g.50.1.2| RP:SCP:REP 698->740|1b71A2|8e-05|21.1|38/44|g.41.5.1| RP:SCP:REP 926->1071|1dq3A1|4e-17|20.7|145/168|b.86.1.2| HM:SCP:REP 926->1122|1dq3A1|1.1e-24|34.4|163/169|b.86.1.2|1/1|Hedgehog/intein (Hint) domain| OP:NHOMO 48 OP:NHOMOORG 45 OP:PATTERN -----------------------111122111111111111111111111111111111111111111 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 258 STR:RPRED 18.8 SQ:SECSTR #########################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################################cccccccccEEccccccEEcccccTTTccccccccccccccccccccTTTGG#GGGTccccccc################################################################################################################################################################################################cccEcEcTTcEEEEEEETTEEEEEEHHHHHHHHTTGGGcEEETTEEEEEEcccEEEEEEcTTTccEEEEEEEEEEEEEEEEEEEEEEETTccEEEEETTcEEEEEETTEEEEEETTTccTTcEEEEEccccccccccEEEHGGGcTTcEETHHHHHHHHHTTEEEEEEEEEEEEEEEEEEEEEEccccEEEETTE############################################################################################################################################################################################################################################################## DISOP:02AL 1-5, 278-290, 622-633, 1054-1063| PSIPRED ccHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccHHHHHHHHccccHHHHHHHHHHHHHcHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHccccccEEEEEEEccccccEEEEEEccccccccHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHccEEEccccccccccccccccccccccccHHHHHHHHHHHHHHHcHHHHHHHHHcccccHHHHHHHHccccccccccccccccccHHHHHccccccccHHccccccEEcccHHHHHHHHccccccccccccccEEEEEcHHHHcEEEEcccccEEEEEEEcEEEccEEEEEEcccccEEEEEEccccccEEEEccccEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHccccccccccccEEcccHHHHHHHHHHHHHcccccccccccccEEccccHHHHHHHHHHcccEEEcccEEEEEEcHHHHHHHcccHHHHHHHHHHHHHHccHHHHHHHHHHHccEEEEccccEEEccccccccccccccccccccEEEcHHHcccccccHHHHHHccccccccccEEEEEEEEEEcccccccccEEEccccccccccEEEccccccccccccccccccccccccccccEEEEccHHHHHHHHHHHHHHccccHHEEHHHHHHccccccccHHHHHHHHHHccEEEEcccEEEEccccccEEEEEHHHHcccHHHHHHcccccccccccccccccEEEEEEEEEEEcHHHHHHHHHHHHHHHHHHHHHcccccccccccHHHHEEEEEEEEccccccHHHEEEEEEEEEEEEEcccHHHHHHHccccccccEEEEEcccccEEEEEHHHHHHHHccccccEEcccccEEEEccccEEEEEEcccccEEEEEEEEEEEccccccEEEEEEccccEEEEcccEEEEEEEccEEEEEEHHHcccccEEEEccccccccccccccccccccccccccccHHccccEEEEEEEEEEEEEccccEEEEEEEcccccEEEEcEEEEccccHHHHHHHHHHHHHHHHHHHccccccccccccEEEEEEEcHHHHHHHHHcHHHHHHccHHHHHHHHccccHHHHHHHHHHHHHHcccccEEEccccccccHHHHccccEEHHHcccHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHccHHHHHHHHHHccccEEEEEccccccccccccccccccccEEEEEEHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHccccccccccHHHcc 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