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Halorubrum lacusprofundi ATCC 49239 (hlac0)
Chromosome : 1
Gene : ACM57612.1
DDBJ      :             glycine hydroxymethyltransferase
Swiss-Prot:GLYA_HALLT   RecName: Full=Serine hydroxymethyltransferase;         Short=Serine methylase;         Short=SHMT;         EC=2.1.2.1;

Homologs  Archaea  61/68 : Bacteria  896/915 : Eukaryota  191/199 : Viruses  1/175   --->[See Alignment]
c.67.1
:415 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   4->409 1kkjA PDBj e-121 53.5 %
:RPS:PDB   1->414 1cj0A PDBj 5e-62 41.1 %
:RPS:SCOP  1->414 1bj4A  c.67.1.4 * e-117 41.8 %
:HMM:SCOP  1->414 2a7vA1 c.67.1.4 * 1.3e-159 55.0 %
:RPS:PFM   8->384 PF00464 * SHMT e-123 58.4 %
:HMM:PFM   7->384 PF00464 * SHMT 9.9e-156 56.3 375/399  
:BLT:SWISS 1->415 GLYA_HALLT 0.0 100.0 %
:PROS 220->236|PS00096|SHMT
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD Abbreviations Back to title page
GT:ID ACM57612.1 GT:GENE ACM57612.1 GT:PRODUCT glycine hydroxymethyltransferase GT:DATABASE GIB00862CH01 GT:ORG hlac0 GB:ACCESSION GIB00862CH01 GB:CHROMOSOME 1 GB:LOCATION complement(2026029..2027276) GB:FROM 2026029 GB:TO 2027276 GB:DIRECTION - GB:PRODUCT glycine hydroxymethyltransferase GB:NOTE PFAM: glycine hydroxymethyltransferase; KEGG: hma:rrnAC0999 serine hydroxymethyltransferase GB:PROTEIN_ID ACM57612.1 GB:DB_XREF GI:222453347 InterPro:IPR001085 LENGTH 415 SQ:AASEQ MDHEHVREVDPEVADALAGERDRQEQTLAMIASENHVSEAVLEAQGSVLTNKYAEGYPGERYYAGCEYADEVETLAIDRAKELWGADHVNVQPHSGTQANQAVYYAVLDPGDKILSLDLNHGGHLSHGHPANFTGQIYEVEQYEVDADTGYIDYEGLREAAEEFEPDIVVSGYSAYPRTVDWEEIQAAADAVDAYHLADIAHITGLVAAGVHPSPVGVADFVTGSTHKTIRAGRGGIVMCDEEFADDIDKAVFPGGQGGPLMHNIAGKAVGFKEALDPSFDEYAQNVVDNAEVLAETLQDHGFSLVSGGTDNHLVLVDLRDSHPDLPGGDAADALAAANIVLNGNTVPGETRSPFNPSGIRVGTAGVTTRGFDADVMEEVGDLIHRVVDNVDSDDVIYEVGERVVELCDEHPLYE GT:EXON 1|1-415:0| SW:ID GLYA_HALLT SW:DE RecName: Full=Serine hydroxymethyltransferase; Short=Serine methylase; Short=SHMT; EC=2.1.2.1; SW:GN Name=glyA; OrderedLocusNames=Hlac_2034; SW:KW Complete proteome; Cytoplasm; One-carbon metabolism;Pyridoxal phosphate; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->415|GLYA_HALLT|0.0|100.0|415/415| GO:SWS:NREP 3 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006730|"GO:one-carbon metabolic process"|One-carbon metabolism| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 220->236|PS00096|SHMT|PDOC00090| SEG 187->199|aaadavdayhlad| SEG 324->338|pdlpggdaadalaaa| BL:PDB:NREP 1 BL:PDB:REP 4->409|1kkjA|e-121|53.5|404/405| RP:PDB:NREP 1 RP:PDB:REP 1->414|1cj0A|5e-62|41.1|411/464| RP:PFM:NREP 1 RP:PFM:REP 8->384|PF00464|e-123|58.4|375/378|SHMT| HM:PFM:NREP 1 HM:PFM:REP 7->384|PF00464|9.9e-156|56.3|375/399|SHMT| GO:PFM:NREP 3 GO:PFM GO:0004372|"GO:glycine hydroxymethyltransferase activity"|PF00464|IPR001085| GO:PFM GO:0006544|"GO:glycine metabolic process"|PF00464|IPR001085| GO:PFM GO:0006563|"GO:L-serine metabolic process"|PF00464|IPR001085| RP:SCP:NREP 1 RP:SCP:REP 1->414|1bj4A|e-117|41.8|411/470|c.67.1.4| HM:SCP:REP 1->414|2a7vA1|1.3e-159|55.0|411/0|c.67.1.4|1/1|PLP-dependent transferases|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s3333275DB2943342223 -----------------------------------1------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 415 STR:RPRED 100.0 SQ:SECSTR cccccHHHHcHHHHHHHHHHHHHHHHcEEccTTcccccHHHHHHTTcGGGGcccccccccccccccTTHHHHHHHHHHHHHHHTTccTEEcccccHHHHHHHHHHHHccTTcEEEEEcTTTTccGGGcccccHHHHHcEEEEEcccTTTccccHHHHHHHHHHHcccEEEEccccccccccHHHHHHHHHHHTcEEEEEcTTTHHHHHHTccccGGGTccEEEEEccccccccccEEEEEcccHHHHHHHHHTTTTcccccHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHTTTcEETTccccccEEEEEGGGGTccHHHHHHHHHHTTEEcEEEccTTcTccccTTcccEEEEEcHHHHTTTccHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHccccH DISOP:02AL 414-416| PSIPRED ccccHHHHccHHHHHHHHHHHHHHHHccEEEEccccccHHHHHHHHHHHHcHHcccccccccccccHHHHHHHHHHHHHHHHHHcccccEEcccccHHHHHHHHHHHcccccEEEEEcccccccccccHHHEEEEEccEEEEcccccccccccHHHHHHHHHHHcccEEEEccccccccccHHHHHHHHHHcccEEEEccHHHHccHHccccccccccccEEEEEccccccccccEEEEEcHHHHHHHHHHccccccccccHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHcccEEEccccccEEEEEEcccccccccHHHHHHHHHHccEEEcccccccccccccccccEEcccHHHHHccccHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHccccc //