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Homo sapiens (cDNA) (huge0)
Gene : KIAA0017
DDBJ      :             KIAA0017
Swiss-Prot:SF3B3_HUMAN  RecName: Full=Splicing factor 3B subunit 3;AltName: Full=Spliceosome-associated protein 130;         Short=SAP 130;AltName: Full=Pre-mRNA-splicing factor SF3b 130 kDa subunit;         Short=SF3b130;AltName: Full=STAF130;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  191/199 : Viruses  0/175   --->[See Alignment]
b.69.4
:1253 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   40->1247 3ei1A PDBj 3e-54 26.1 %
:RPS:PDB   38->661,859->1248 2b5lB PDBj 8e-33 20.5 %
:HMM:SCOP  567->1094 1pguA1 b.69.4.1 * 0.00062 18.0 %
:RPS:PFM   902->1218 PF03178 * CPSF_A 9e-64 45.6 %
:HMM:PFM   899->1219 PF03178 * CPSF_A 2.3e-102 44.3 300/321  
:BLT:SWISS 37->1253 SF3B3_HUMAN 0.0 100.0 %
:PROS 323->329|PS00290|IG_MHC
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0017 GT:ORG huge0 GT:GENE KIAA0017 GT:PRODUCT KIAA0017 GT:DATABASE huge2038 LENGTH 1253 SQ:AASEQ HPLDIHTILLAAGFLGLRTVGVTKAWRSGWLRFPAAMFLYNLTLQRATGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFGVIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPGGSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKITLETDEDMVTEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDTPQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHIEDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVNEWKTPGKKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGTEKQDELGERGSIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTGEDWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRGLLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDFFQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRTPPEVSKKLEDIRTRYAF SW:ID SF3B3_HUMAN SW:DE RecName: Full=Splicing factor 3B subunit 3;AltName: Full=Spliceosome-associated protein 130; Short=SAP 130;AltName: Full=Pre-mRNA-splicing factor SF3b 130 kDa subunit; Short=SF3b130;AltName: Full=STAF130; SW:GN Name=SF3B3; Synonyms=KIAA0017, SAP130; SW:KW Acetylation; Alternative splicing; Complete proteome; mRNA processing;mRNA splicing; Nucleus; Polymorphism; Spliceosome. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 37->1253|SF3B3_HUMAN|0.0|100.0|1217/1217| GO:SWS:NREP 4 GO:SWS GO:0006397|"GO:mRNA processing"|mRNA processing| GO:SWS GO:0008380|"GO:RNA splicing"|mRNA splicing| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0005681|"GO:spliceosomal complex"|Spliceosome| PROS 323->329|PS00290|IG_MHC|PDOC00262| SEG 752->764|ssrswlsysyqsr| BL:PDB:NREP 1 BL:PDB:REP 40->1247|3ei1A|3e-54|26.1|1074/1105| RP:PDB:NREP 1 RP:PDB:REP 38->661,859->1248|2b5lB|8e-33|20.5|944/1134| RP:PFM:NREP 1 RP:PFM:REP 902->1218|PF03178|9e-64|45.6|294/305|CPSF_A| HM:PFM:NREP 1 HM:PFM:REP 899->1219|PF03178|2.3e-102|44.3|300/321|CPSF_A| GO:PFM:NREP 2 GO:PFM GO:0003676|"GO:nucleic acid binding"|PF03178|IPR004871| GO:PFM GO:0005634|"GO:nucleus"|PF03178|IPR004871| HM:SCP:REP 567->1094|1pguA1|0.00062|18.0|205/0|b.69.4.1|1/1|WD40 repeat-like| OP:NHOMO 425 OP:NHOMOORG 191 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111221-1---22311111111111111111111211113111111111142111121111111111-11111111-1111111111-22212111111121232-22352234142212221442426R213262221212222221222142622249F23232324722231222Q2222263641632232221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1207 STR:RPRED 96.3 SQ:SECSTR #####################################cEEEEEccccccccEEEEEccccccccEEEEEcccEEEEEEEcccEEcEEEEEEEEccccEEEEEEEccTTccccEEEEEETTcEEEEEEEcccTTcccEEEEEEEEcccccccccccEEEEcTTccEEEEEccTTccEEEEccccccccccEEEEcccTTcccccccccccEEEEccccccccccEEEEEEEcccEEEEEEEEEETTTTEEcccccEEEEEEEccTTTcccEEEEcc###TTTccEcccccccccccccTTEEEEEcccccccccEEEETTEEEEccccccccccccccccccccEEEEccTTcccEEEEccccEEccEEEEEEEcccccEEEEEEEEcccEEcccccEEEEccccEEEEEcccccEEEEEEcccccGGGccEEEEEEEcccccEEEEEEEccccTTccEEEEEEccGGGcEEEEEEEEccEEEEEEEEEEcTccEEEEEccccccccccEEEEEccccccEEEcTTcccccccTTTcccccccEEEEETTTEEEEEccccEEEccccccccccccTTcccccEEEEcccEEEEEcccEEEEEEEETTEEEEEEEEEEEEccccEEEEEcccccccTTccEEEEEEccccEEEEEETTTTcccEEEEEccccccEEEEEcccccccccEEEEEEEEETTEEEEEEEETTcEEEEEEEcTTTccEEEEEEEEccccccEEEEEEccccEEEEEEccccEEEEccccccEEEEcccccccEEEEEcccccccEEEEEccccEEEEEEcccccEEEEEE#EcccEEEEEEEETTTTEEEEEccETTEEEGGGTEEEEEEEEEEEcccccccccccccGGGcccEEEccccccccccccccEEEEEEEEEEETTTccEEEEEEccTTEEEEEEEEEccTTcccccEEEEEEEEccTTccccccEcccEEEEEEccccccEEccccEEcccccEEEEETTEEEEEccccEEEEEEcTTccEEEEEEEcccccEEEEEEETTEEEEEEccccEEEEEEETTTTEEEEEEEccccccEEEEEEccccEEEEEETTcEEEEEEccccccHHHHccccEEEEEEEccccHHHHTcEccEEEEEEcccccccccccccccEEEEEEEEETTcccEEEEEccHHHHHHHHHHHHHHHHHHccccccccHHHHHcccccccccccHHHHHGGGGccHHHHHHTTTTcEccHHHHHHHHHHHT##### DISOP:02AL 1-1,1101-1101,1144-1147,1253-1254| PSIPRED cccccEEHHHHHHHHcEEEEccccHHHEEEEEcccccEEEEEEEEcccEEEEEEEEEEcccccEEEEEEcccEEEEEEEcccccEEEEEEEEEEEEEEEEEEEEccccccccEEEEEEcccEEEEEEEEccccEEEEEcccccccccEEccccccEEEEcccccEEEEEEccccEEEEEEcccccccEEcccEEEEcccccEEEEEEEEEccccccEEEEEEEEccccccccccEEEEEccEEEEEEEEcccccEEEEEEEccccccccEEEEcccccccccEEEEEEccEEEEEcccccccEEEEcccccccccccccccEEEEEEEEcccccEEEEEEcccccEEEEEEEEcccEEEEEEEEEEccccccEEEEEEcccEEEEEEccccEEEEEEccccccccccccccccccccccEEEEcccccccEEEEEEcccccccEEEEEEEccccccccEEEEEEcccccEEEEEEcccccEEEEEEEccccccEEEEEEcccccccccEEEEEEccccEEEEEcccEEEEccccccccccEEEEEEcccccEEEEEccEEEEEEccccEEEEEcccccEEEEEEEcccEEEEEEEcccEEEEEEcccccEEEEEcccccccccEEEEEccccccccEEEEEEEEEccccEEEEEEcccccEEEEEEEEcccccccEEEEEcccccccccccccccccEEEEEEEEcccEEEEEEEEcccEEEEEEEEEEEccccEEEEEEEcccccEEEEEEcccEEEEEEcccccccccccccccccccccHHccccEEEEEEcccEEEEEEcccccccccEEEEcccccEEEEEcccccEEEEEEEcccccccccccccccccccHHHHHHccccccccccHHHcccccccccccccccccccccEEEEEEEEEcccccEEEEEEccccccEEEEEEEEcccccccEEEEEEEEEcccccccccccEEEEEEEEEccccEEEEEEEEEcccccEEEEEEccEEEEEEccEEEEEEcccHHHEEHHHcccccEEEEEEEEcccEEEEEEEcccEEEEEEEccccEEEEEEcccccccEEEEEEEEccEEEEEcccccEEEEEEcccccccccccccccEEEEcccccccccccEEEEEEEcccccEEEEEccccccccccEEEEEEccccEEEEEEEccHHHHHHHHHHHHHHHHcccccccccHHHHccccccccccccHHHHHHHHcccHHHHHHHHHHHcccHHHHHHHHHHHHHcccc //