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Homo sapiens (cDNA) (huge0)
Gene : KIAA0043
DDBJ      :             KIAA0043
Swiss-Prot:BRD3_HUMAN   RecName: Full=Bromodomain-containing protein 3;AltName: Full=RING3-like protein;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
a.29.2
:731 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   39->153 2yw5A PDBj 8e-67 100.0 %
:BLT:PDB   312->421 2oo1A PDBj 1e-63 100.0 %
:BLT:PDB   576->649 2jnsA PDBj 2e-33 90.4 %
:RPS:PDB   39->148 3dwyA PDBj 8e-30 31.5 %
:RPS:PDB   315->422 2e3kD PDBj 7e-34 84.3 %
:RPS:SCOP  39->148 3dwyA1  a.29.2.1 * 1e-30 31.5 %
:RPS:SCOP  312->423 3dwyA1  a.29.2.1 * 4e-31 35.5 %
:HMM:SCOP  18->158 1eqfA1 a.29.2.1 * 1.1e-44 34.5 %
:HMM:SCOP  268->433 1eqfA1 a.29.2.1 * 7.1e-43 39.6 %
:RPS:PFM   50->127 PF00439 * Bromodomain 3e-14 48.7 %
:RPS:PFM   323->402 PF00439 * Bromodomain 8e-15 52.0 %
:HMM:PFM   51->131 PF00439 * Bromodomain 1.6e-23 35.4 79/84  
:HMM:PFM   320->408 PF00439 * Bromodomain 2.7e-25 44.0 84/84  
:HMM:PFM   626->725 PF08418 * Pol_alpha_B_N 9.9e-07 24.7 97/253  
:HMM:PFM   434->556 PF04520 * DUF584 5.8e-05 28.3 106/152  
:BLT:SWISS 6->696 BRD3_HUMAN 0.0 100.0 %
:PROS 61->120|PS00633|BROMODOMAIN_1
:PROS 336->395|PS00633|BROMODOMAIN_1
:REPEAT 2|39->148|312->423
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0043 GT:ORG huge0 GT:GENE KIAA0043 GT:PRODUCT KIAA0043 GT:DATABASE huge2038 LENGTH 731 SQ:AASEQ VSCRRMSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE SW:ID BRD3_HUMAN SW:DE RecName: Full=Bromodomain-containing protein 3;AltName: Full=RING3-like protein; SW:GN Name=BRD3; Synonyms=KIAA0043, RING3L; SW:KW 3D-structure; Alternative splicing; Bromodomain;Chromosomal rearrangement; Coiled coil; Complete proteome; Nucleus;Phosphoprotein; Polymorphism; Repeat. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 6->696|BRD3_HUMAN|0.0|100.0|691/726| GO:SWS:NREP 1 GO:SWS GO:0005634|"GO:nucleus"|Nucleus| PROS 61->120|PS00633|BROMODOMAIN_1|PDOC00550| PROS 336->395|PS00633|BROMODOMAIN_1|PDOC00550| NREPEAT 1 REPEAT 2|39->148|312->423| SEG 21->38|pgpvnppppevsnpskpg| SEG 154->168|ppapkgkgrkpaaga| SEG 213->266|vtsvpvppaaappppatpivpvvpptppvvkkkgvkrkadtttpttsaitasrs| SEG 424->436|pveapalpapaap| SEG 441->465|gaessrsseesssdsgssdseeera| SEG 488->545|apvnkpkkkkekkekekkkkdkekekekhkvkaeeekkakvappakqaqqkkapakka| SEG 569->573|eeeee| SEG 651->678|sasgkkqaakskeelaqekkkelekrlq| SEG 697->730|gsapsggpsrlssssssesgsssssgsssdssds| BL:PDB:NREP 3 BL:PDB:REP 39->153|2yw5A|8e-67|100.0|115/138| BL:PDB:REP 312->421|2oo1A|1e-63|100.0|110/110| BL:PDB:REP 576->649|2jnsA|2e-33|90.4|73/90| RP:PDB:NREP 2 RP:PDB:REP 39->148|3dwyA|8e-30|31.5|110/114| RP:PDB:REP 315->422|2e3kD|7e-34|84.3|108/109| RP:PFM:NREP 2 RP:PFM:REP 50->127|PF00439|3e-14|48.7|76/84|Bromodomain| RP:PFM:REP 323->402|PF00439|8e-15|52.0|75/84|Bromodomain| HM:PFM:NREP 4 HM:PFM:REP 51->131|PF00439|1.6e-23|35.4|79/84|Bromodomain| HM:PFM:REP 320->408|PF00439|2.7e-25|44.0|84/84|Bromodomain| HM:PFM:REP 626->725|PF08418|9.9e-07|24.7|97/253|Pol_alpha_B_N| HM:PFM:REP 434->556|PF04520|5.8e-05|28.3|106/152|DUF584| RP:SCP:NREP 2 RP:SCP:REP 39->148|3dwyA1|1e-30|31.5|110/114|a.29.2.1| RP:SCP:REP 312->423|3dwyA1|4e-31|35.5|110/114|a.29.2.1| HM:SCP:REP 18->158|1eqfA1|1.1e-44|34.5|139/0|a.29.2.1|1/2|Bromodomain| HM:SCP:REP 268->433|1eqfA1|7.1e-43|39.6|139/0|a.29.2.1|2/2|Bromodomain| OP:NHOMO 1901 OP:NHOMOORG 195 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 2256323-2--13352222322224243333133232222112222323333453455433322222222222223333323332233-469213332242236582373FIQNPPOEEECCJCvdCpD**Y4fLdDDA9ODIKBCFBCCSBAZDPHJC66DHAAD6K77D7F994235Z554327BII3F36548864 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 323 STR:RPRED 44.2 SQ:SECSTR ######################################ccHcTTHHHHHHHHHHHHHcTTcGGGcccccHHTTTcTTHHHHccccccHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHccTTcHHHHHHHHHHHHHHHHHHTcGGGGGGcc#######################################################################################################################################ccccccccTTHHHHHHHHHHccccccHHHHHHHHHHHHHHcGGGHHHHGGGcccccHHHHTcTTHHHHccccccHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHccTTcHHHHHHHHHHHHHHHHHHTcccH########################################################################################################################################################cccHHHHHHHHHHHTTccHHHHTTHHHHHHTTcGGGTTccTTcccccTTTccHHHHHHHHHHHHTTcccc#ccc################################################################################## DISOP:02AL 1-45,154-314,420-596,604-620,640-732| PSIPRED cccccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHcccccHHHHcccccHHHccccHHHHHcccccHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHccHHHHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHHHHccHHHHHHHHHHHHHHHHHccccHHHHHHHHccccHHHccccHHHHHHccccHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHHHHHHHHHccccccccccccccccccccccccccccccccccccHHHHHccccccHHHHHHHHHHHHHccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHHcccHHHHHHHHHHHHHcccccccccccEEEEEHHHccHHHHHHHHHHHHHHHHHHHcccccccccccccccHHHHcHHHHHHHHHHHHHHccccccccccccccccccccccccccccccccccccccccccccccccccc //