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Homo sapiens (cDNA) (huge0)
Gene : KIAA0060
DDBJ      :             KIAA0060
Swiss-Prot:GNPI1_HUMAN  RecName: Full=Glucosamine-6-phosphate isomerase 1;         EC=3.5.99.6;AltName: Full=Glucosamine-6-phosphate deaminase 1;         Short=GlcN6P deaminase 1;         Short=GNPDA 1;AltName: Full=Oscillin;

Homologs  Archaea  0/68 : Bacteria  391/915 : Eukaryota  144/199 : Viruses  0/175   --->[See Alignment]
c.124.1
:317 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   29->300 1ne7B PDBj e-162 100.0 %
:RPS:PDB   15->280 3e15B PDBj 1e-75 17.8 %
:RPS:SCOP  30->246 1pbtA  c.124.1.1 * 1e-41 22.8 %
:HMM:SCOP  29->294 1deaA_ c.124.1.1 * 4e-105 55.6 %
:RPS:PFM   60->275 PF01182 * Glucosamine_iso 4e-71 58.3 %
:HMM:PFM   43->278 PF01182 * Glucosamine_iso 1e-138 70.3 236/236  
:BLT:SWISS 29->317 GNPI1_HUMAN e-163 100.0 %
:PROS 153->171|PS01161|GLC_GALNAC_ISOMERASE
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0060 GT:ORG huge0 GT:GENE KIAA0060 GT:PRODUCT KIAA0060 GT:DATABASE huge2038 LENGTH 317 SQ:AASEQ VLLSQFLHRRKRLRENLGPLTEVLQVDKMKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD SW:ID GNPI1_HUMAN SW:DE RecName: Full=Glucosamine-6-phosphate isomerase 1; EC=3.5.99.6;AltName: Full=Glucosamine-6-phosphate deaminase 1; Short=GlcN6P deaminase 1; Short=GNPDA 1;AltName: Full=Oscillin; SW:GN Name=GNPDA1; Synonyms=GNPI, HLN, KIAA0060; SW:KW 3D-structure; Acetylation; Carbohydrate metabolism; Complete proteome;Cytoplasm; Hydrolase. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 29->317|GNPI1_HUMAN|e-163|100.0|289/289| GO:SWS:NREP 3 GO:SWS GO:0005975|"GO:carbohydrate metabolic process"|Carbohydrate metabolism| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| PROS 153->171|PS01161|GLC_GALNAC_ISOMERASE|PDOC00894| SEG 301->313|keketeksqsskk| BL:PDB:NREP 1 BL:PDB:REP 29->300|1ne7B|e-162|100.0|272/274| RP:PDB:NREP 1 RP:PDB:REP 15->280|3e15B|1e-75|17.8|259/287| RP:PFM:NREP 1 RP:PFM:REP 60->275|PF01182|4e-71|58.3|216/229|Glucosamine_iso| HM:PFM:NREP 1 HM:PFM:REP 43->278|PF01182|1e-138|70.3|236/236|Glucosamine_iso| GO:PFM:NREP 1 GO:PFM GO:0005975|"GO:carbohydrate metabolic process"|PF01182|IPR006148| RP:SCP:NREP 1 RP:SCP:REP 30->246|1pbtA|1e-41|22.8|197/220|c.124.1.1| HM:SCP:REP 29->294|1deaA_|4e-105|55.6|266/0|c.124.1.1|1/1|NagB/RpiA/CoA transferase-like| OP:NHOMO 749 OP:NHOMOORG 535 OP:PATTERN -------------------------------------------------------------------- -11-1111111-11-----------2-----------311-----21-1121123--1----11---111-----11111111-----22321322----14--111414-------------------------------------11-11---11-11111----1111-1-----1-----------1--1111111111111111112212111111211144444211-11111111111111211122111111-11111111111111122211111111111111111111111111111111111221112221-11111111111111-1--111111-1-111--11----11--111--111-4------------------------------------------1------------------------1------------------1-------------------------------------------------------------------------------------1--------------------------------1-----------------1-11---------------------------111---1--11-------1----1-21-11-------------11111212112222222-1222222222122222223222111111111111111111111111133211-11111111111111-------------1-1111-111111-1111-----------1---------------------------11121111111111-----------------3------111111111-1--------2-1--111-21-11--------------11 ----221-2112---1-1112111111111111111121111111111112222221-11111-1----1--1-1------11111---112-21-1111--1534-1-1224122-2222222321223G21225222332222222222234222222221111121771121--------1-----1--------3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 299 STR:RPRED 94.3 SQ:SECSTR #HHHHHHHHHHHHHHHHHHHHHTEEETTEEEEEcccHHHHHHHHHHHHHHHHHHHHHHcGGccEEEEcccHHHHHHHHHHTTcccHccccGGGcEEEEcEEEccTTccTTcHHHHHHHHHHHHHTTccHHHHEEcccTTccHHHHHHHHHHHHHHHccccEEEEcccTTcccTTcGGGcccccccHHHHHcHTTccccEEEEcEcccTTccEEEEEcHHHHHTccEEEEEEccHHHHHHHHHHHHHTTTTTcHHHHHHHTcEEEEEcccTTHHHHHHHHcHHHHHTHHHHGGGTcccccc################# DISOP:02AL 5-7,299-318| PSIPRED ccHHHHHHHHHHHccccccccccccccccEEEEEccHHHHHHHHHHHHHHHHHHHcccccccEEEEEcccccHHHHHHHHHHHHHcccccHHHEEEEEcccccccccccHHHHHHHHHHHHHHHccccHHHccccccccccHHHHHHHHHHHHHHcccccEEEEEEcccccEEEccccccccccccEEEEccccHHHcccccccccccccccEEEccHHHHHHccEEEEEEccHHHHHHHHHHHHccccccccHHHHHccccEEEEEcHHHHcccccHHHHHHHHHHHHHHHHcccccccHHHcccccccccccccc //