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Homo sapiens (cDNA) (huge0)
Gene : KIAA0065
DDBJ      :             KIAA0065
Swiss-Prot:ZN33A_HUMAN  RecName: Full=Zinc finger protein 33A;AltName: Full=Zinc finger protein 11A;AltName: Full=Zinc finger protein KOX31;AltName: Full=Zinc finger and ZAK-associated protein with KRAB domain;         Short=ZZaPK;

Homologs  Archaea  0/68 : Bacteria  1/915 : Eukaryota  186/199 : Viruses  0/175   --->[See Alignment]
a.138.1a.212.1b.88.1g.37.1g.41.3
:848 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   50->91 1v65A PDBj 1e-09 54.8 %
:BLT:PDB   178->303 2i13A PDBj 1e-05 25.4 %
:BLT:PDB   336->393 2cotA PDBj 8e-12 46.6 %
:BLT:PDB   375->528 2i13A PDBj 1e-56 62.3 %
:BLT:PDB   530->561 2eneA PDBj 1e-08 65.6 %
:BLT:PDB   543->696 2i13A PDBj 9e-56 61.0 %
:BLT:PDB   672->815 2i13B PDBj 1e-48 56.9 %
:RPS:PDB   245->396 2dhmA PDBj 1e-04 5.9 %
:RPS:PDB   353->452 2dhmA PDBj 2e-22 10.9 %
:RPS:PDB   425->795 1ej6C PDBj 8e-60 9.6 %
:RPS:PDB   767->812 1d9uA PDBj 9e-09 19.6 %
:RPS:SCOP  27->154 1txjA  b.88.1.2 * 3e-18 13.8 %
:RPS:SCOP  336->386 1vd4A  g.41.3.1 * 2e-06 17.6 %
:RPS:SCOP  357->817 1fgjA  a.138.1.3 * 1e-44 8.0 %
:HMM:SCOP  43->106 1v65A_ a.212.1.1 * 9.5e-27 60.9 %
:HMM:SCOP  334->389 1yujA_ g.37.1.1 * 1.1e-09 47.9 %
:HMM:SCOP  364->416 2cshA1 g.37.1.1 * 5.4e-19 58.5 %
:HMM:SCOP  402->457 1x3cA1 g.37.1.1 * 5.3e-24 69.6 %
:HMM:SCOP  444->471 1bhiA_ g.37.1.1 * 1e-08 64.3 %
:HMM:SCOP  458->513 1x3cA1 g.37.1.1 * 2.2e-21 66.1 %
:HMM:SCOP  500->527 1bhiA_ g.37.1.1 * 2.7e-08 71.4 %
:HMM:SCOP  514->569 1x3cA1 g.37.1.1 * 8.8e-21 64.3 %
:HMM:SCOP  556->583 1bhiA_ g.37.1.1 * 1.6e-07 64.3 %
:HMM:SCOP  570->625 1x3cA1 g.37.1.1 * 1.8e-21 64.3 %
:HMM:SCOP  612->639 1bhiA_ g.37.1.1 * 1.5e-07 64.3 %
:HMM:SCOP  626->681 1x3cA1 g.37.1.1 * 2e-23 69.6 %
:HMM:SCOP  668->695 1bhiA_ g.37.1.1 * 8.9e-09 71.4 %
:HMM:SCOP  682->737 1x3cA1 g.37.1.1 * 1.1e-21 67.9 %
:HMM:SCOP  724->751 1bhiA_ g.37.1.1 * 3.7e-08 67.9 %
:HMM:SCOP  738->793 1x3cA1 g.37.1.1 * 4.6e-19 62.5 %
:HMM:SCOP  778->813 2ct1A2 g.37.1.1 * 5.5e-11 58.3 %
:RPS:PFM   50->90 PF01352 * KRAB 1e-13 70.7 %
:HMM:PFM   366->388 PF00096 * zf-C2H2 1.1e-06 52.2 23/23  
:HMM:PFM   394->416 PF00096 * zf-C2H2 6.8e-07 52.2 23/23  
:HMM:PFM   422->444 PF00096 * zf-C2H2 2.2e-08 52.2 23/23  
:HMM:PFM   450->472 PF00096 * zf-C2H2 3.1e-08 56.5 23/23  
:HMM:PFM   478->500 PF00096 * zf-C2H2 5.9e-08 52.2 23/23  
:HMM:PFM   506->528 PF00096 * zf-C2H2 4.6e-09 60.9 23/23  
:HMM:PFM   534->556 PF00096 * zf-C2H2 4.1e-07 52.2 23/23  
:HMM:PFM   562->584 PF00096 * zf-C2H2 2.9e-07 52.2 23/23  
:HMM:PFM   590->612 PF00096 * zf-C2H2 1.4e-07 56.5 23/23  
:HMM:PFM   618->640 PF00096 * zf-C2H2 5.7e-07 52.2 23/23  
:HMM:PFM   646->668 PF00096 * zf-C2H2 4.8e-08 52.2 23/23  
:HMM:PFM   674->696 PF00096 * zf-C2H2 7.5e-08 52.2 23/23  
:HMM:PFM   702->724 PF00096 * zf-C2H2 2.5e-06 56.5 23/23  
:HMM:PFM   730->752 PF00096 * zf-C2H2 1.1e-06 52.2 23/23  
:HMM:PFM   758->780 PF00096 * zf-C2H2 2.2e-07 56.5 23/23  
:HMM:PFM   786->808 PF00096 * zf-C2H2 5.9e-09 60.9 23/23  
:HMM:PFM   50->90 PF01352 * KRAB 3.9e-27 78.0 41/41  
:BLT:SWISS 39->848 ZN33A_HUMAN 0.0 100.0 %
:PROS 368->388|PS00028|ZINC_FINGER_C2H2_1
:PROS 396->416|PS00028|ZINC_FINGER_C2H2_1
:PROS 424->444|PS00028|ZINC_FINGER_C2H2_1
:PROS 452->472|PS00028|ZINC_FINGER_C2H2_1
:PROS 480->500|PS00028|ZINC_FINGER_C2H2_1
:PROS 508->528|PS00028|ZINC_FINGER_C2H2_1
:PROS 536->556|PS00028|ZINC_FINGER_C2H2_1
:PROS 564->584|PS00028|ZINC_FINGER_C2H2_1
:PROS 592->612|PS00028|ZINC_FINGER_C2H2_1
:PROS 620->640|PS00028|ZINC_FINGER_C2H2_1
:PROS 648->668|PS00028|ZINC_FINGER_C2H2_1
:PROS 676->696|PS00028|ZINC_FINGER_C2H2_1
:PROS 704->724|PS00028|ZINC_FINGER_C2H2_1
:PROS 732->752|PS00028|ZINC_FINGER_C2H2_1
:PROS 758->780|PS00028|ZINC_FINGER_C2H2_1
:PROS 788->808|PS00028|ZINC_FINGER_C2H2_1
:REPEAT 18|178->203|339->364|367->392|395->420|423->448|451->476|479->504|507->532|535->560|563->588|591->616|619->644|647->672|675->700|703->728|731->756|759->784|787->812

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0065 GT:ORG huge0 GT:GENE KIAA0065 GT:PRODUCT KIAA0065 GT:DATABASE huge2038 LENGTH 848 SQ:AASEQ GGGPGISRVYALFYGECNPTREWAVSSELSPSFQEQNKMNKVEQKSQESVSFKDVTVGFTQEEWQHLDPSQRALYRDVMLENYSNLVSVGYCVHKPEVIFRLQQGEEPWKQEEEFPSQSFPVWTADHLKERSQENQSKHLWEVVFINNEMLTKEQGDVIGIPFNVDVSSFPSRKMFCQCDSCGMSFNTVSELVISKINYLGKKSDEFNACGKLLLNIKHDETHTQEKNEVLKNRNTLSHHEETLQHEKIQTLEHNFEYSICQETLLEKAVFNTQKRENAEENNCDYNEFGRTLCDSSSLLFHQISPSRDNHYEFSDCEKFLCVKSTLSKPHGVSMKHYDCGESGNNFRRKLCLSHLQKGDKGEKHFECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTHTGLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYECNACGKTFYHKSLLTRHQIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECHECGKIFYNKSYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRRHIGENLMNEMDIRNFQPQVSLHNASEYSHCGESPDDILNVQ SW:ID ZN33A_HUMAN SW:DE RecName: Full=Zinc finger protein 33A;AltName: Full=Zinc finger protein 11A;AltName: Full=Zinc finger protein KOX31;AltName: Full=Zinc finger and ZAK-associated protein with KRAB domain; Short=ZZaPK; SW:GN Name=ZNF33A; Synonyms=KIAA0065, KOX31, ZNF11, ZNF11A, ZNF33; SW:KW Complete proteome; DNA-binding; Metal-binding; Nucleus;Phosphoprotein; Polymorphism; Repeat; Transcription;Transcription regulation; Zinc; Zinc-finger. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 39->848|ZN33A_HUMAN|0.0|100.0|810/810| GO:SWS:NREP 5 GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation| PROS 368->388|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 396->416|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 424->444|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 452->472|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 480->500|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 508->528|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 536->556|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 564->584|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 592->612|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 620->640|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 648->668|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 676->696|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 704->724|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 732->752|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 758->780|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 788->808|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| NREPEAT 1 REPEAT 18|178->203|339->364|367->392|395->420|423->448|451->476|479->504|507->532|535->560|563->588|591->616|619->644|647->672|675->700|703->728|731->756|759->784|787->812| BL:PDB:NREP 7 BL:PDB:REP 50->91|1v65A|1e-09|54.8|42/64| BL:PDB:REP 178->303|2i13A|1e-05|25.4|123/151| BL:PDB:REP 336->393|2cotA|8e-12|46.6|58/77| BL:PDB:REP 375->528|2i13A|1e-56|62.3|151/151| BL:PDB:REP 530->561|2eneA|1e-08|65.6|32/46| BL:PDB:REP 543->696|2i13A|9e-56|61.0|151/151| BL:PDB:REP 672->815|2i13B|1e-48|56.9|144/144| RP:PDB:NREP 4 RP:PDB:REP 245->396|2dhmA|1e-04|5.9|99/107| RP:PDB:REP 353->452|2dhmA|2e-22|10.9|100/107| RP:PDB:REP 425->795|1ej6C|8e-60|9.6|324/1221| RP:PDB:REP 767->812|1d9uA|9e-09|19.6|43/154| RP:PFM:NREP 1 RP:PFM:REP 50->90|PF01352|1e-13|70.7|41/41|KRAB| HM:PFM:NREP 17 HM:PFM:REP 366->388|PF00096|1.1e-06|52.2|23/23|zf-C2H2| HM:PFM:REP 394->416|PF00096|6.8e-07|52.2|23/23|zf-C2H2| HM:PFM:REP 422->444|PF00096|2.2e-08|52.2|23/23|zf-C2H2| HM:PFM:REP 450->472|PF00096|3.1e-08|56.5|23/23|zf-C2H2| HM:PFM:REP 478->500|PF00096|5.9e-08|52.2|23/23|zf-C2H2| HM:PFM:REP 506->528|PF00096|4.6e-09|60.9|23/23|zf-C2H2| HM:PFM:REP 534->556|PF00096|4.1e-07|52.2|23/23|zf-C2H2| HM:PFM:REP 562->584|PF00096|2.9e-07|52.2|23/23|zf-C2H2| HM:PFM:REP 590->612|PF00096|1.4e-07|56.5|23/23|zf-C2H2| HM:PFM:REP 618->640|PF00096|5.7e-07|52.2|23/23|zf-C2H2| HM:PFM:REP 646->668|PF00096|4.8e-08|52.2|23/23|zf-C2H2| HM:PFM:REP 674->696|PF00096|7.5e-08|52.2|23/23|zf-C2H2| HM:PFM:REP 702->724|PF00096|2.5e-06|56.5|23/23|zf-C2H2| HM:PFM:REP 730->752|PF00096|1.1e-06|52.2|23/23|zf-C2H2| HM:PFM:REP 758->780|PF00096|2.2e-07|56.5|23/23|zf-C2H2| HM:PFM:REP 786->808|PF00096|5.9e-09|60.9|23/23|zf-C2H2| HM:PFM:REP 50->90|PF01352|3.9e-27|78.0|41/41|KRAB| GO:PFM:NREP 3 GO:PFM GO:0003676|"GO:nucleic acid binding"|PF01352|IPR001909| GO:PFM GO:0005622|"GO:intracellular"|PF01352|IPR001909| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01352|IPR001909| RP:SCP:NREP 3 RP:SCP:REP 27->154|1txjA|3e-18|13.8|123/157|b.88.1.2| RP:SCP:REP 336->386|1vd4A|2e-06|17.6|48/62|g.41.3.1| RP:SCP:REP 357->817|1fgjA|1e-44|8.0|449/499|a.138.1.3| HM:SCP:REP 43->106|1v65A_|9.5e-27|60.9|64/64|a.212.1.1|1/1|KRAB domain (Kruppel-associated box)| HM:SCP:REP 334->389|1yujA_|1.1e-09|47.9|48/54|g.37.1.1|3/11|C2H2 and C2HC zinc fingers| HM:SCP:REP 364->416|2cshA1|5.4e-19|58.5|53/0|g.37.1.1|4/11|C2H2 and C2HC zinc fingers| HM:SCP:REP 402->457|1x3cA1|5.3e-24|69.6|56/0|g.37.1.1|5/12|C2H2 and C2HC zinc fingers| HM:SCP:REP 444->471|1bhiA_|1e-08|64.3|28/0|g.37.1.1|6/18|C2H2 and C2HC zinc fingers| HM:SCP:REP 458->513|1x3cA1|2.2e-21|66.1|56/0|g.37.1.1|6/12|C2H2 and C2HC zinc fingers| HM:SCP:REP 500->527|1bhiA_|2.7e-08|71.4|28/0|g.37.1.1|8/18|C2H2 and C2HC zinc fingers| HM:SCP:REP 514->569|1x3cA1|8.8e-21|64.3|56/0|g.37.1.1|7/12|C2H2 and C2HC zinc fingers| HM:SCP:REP 556->583|1bhiA_|1.6e-07|64.3|28/0|g.37.1.1|10/18|C2H2 and C2HC zinc fingers| HM:SCP:REP 570->625|1x3cA1|1.8e-21|64.3|56/0|g.37.1.1|8/12|C2H2 and C2HC zinc fingers| HM:SCP:REP 612->639|1bhiA_|1.5e-07|64.3|28/0|g.37.1.1|12/18|C2H2 and C2HC zinc fingers| HM:SCP:REP 626->681|1x3cA1|2e-23|69.6|56/0|g.37.1.1|9/12|C2H2 and C2HC zinc fingers| HM:SCP:REP 668->695|1bhiA_|8.9e-09|71.4|28/0|g.37.1.1|14/18|C2H2 and C2HC zinc fingers| HM:SCP:REP 682->737|1x3cA1|1.1e-21|67.9|56/0|g.37.1.1|10/12|C2H2 and C2HC zinc fingers| HM:SCP:REP 724->751|1bhiA_|3.7e-08|67.9|28/0|g.37.1.1|16/18|C2H2 and C2HC zinc fingers| HM:SCP:REP 738->793|1x3cA1|4.6e-19|62.5|56/0|g.37.1.1|11/12|C2H2 and C2HC zinc fingers| HM:SCP:REP 778->813|2ct1A2|5.5e-11|58.3|36/0|g.37.1.1|18/18|C2H2 and C2HC zinc fingers| OP:NHOMO 35014 OP:NHOMOORG 187 OP:PATTERN -------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111229-1---AAIDAC7EFEEFFAFDDADACBBAA7776999ABBCDFDADDAAC7EBDC9987873BAAA77884998BBBBB65-5G7A96676775A9XWd1D91*************************************************************u**W3--5S-11--96A6F57--KJKJ- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 747 STR:RPRED 88.1 SQ:SECSTR #################################################ccccccTTcccHHHHHTccHHHHHHHHHHHHHTTTccccccc############################################ccccEEcTTccEEcccHHHH#HHTTcccEEEEEEcccEEEEEEEEEEEEcTTccHHHHHHHHHHHHHHHcccEEEEEEEccccccccEEEEEEEEEccccccccccccccEEEEccGGGTTTccTTTTccTTcEEEEEcccccHHHHHHHccHHHHHHHHHTTcEEEEEcHHHHHHHTTcTTccHHHHHHHHHHHcccccHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHcccccccGGGGGccccccccccccHHHHHTHTTcHHHHTTcGGGccGGGccTcccccccccccTTcccccccccccccHHHHHHHHHHHHcccccccTTcccTTcccccccccHHHHHHHHHHHHHHHHHHHTTcccccccccEcccccccTTcccccTTccTTcccTTccHHHHHHHHHTTccccccccccTTTccccccHHHHHHHHGGGTccccccTTEEEEETTEEEccccEEEEEcccEEEEEccccccEEEEEEETTccccTTccccEEEEEEEEcccccccccccEEEcccccccccEEccccccEEEEEEEcccccccccEEEEEEEEcccccccccEEEEEEcTTccccccccccccTTcccGGGGcccccccccccHHHHHHHHHHTTccEEccccEEEcccGGGTTcEEEccHHHHHHHHHHHHHHHHHHHHHHHTTcEEEEcccTEEEccTTccccc####### DISOP:02AL 1-4,23-46,129-135| PSIPRED cccccHHHHHHHHHccccHHHHHHccHHccHHHHHHHcccccccccccccEEEEEEEEccHHHHHHccHHHHHHHHHHHcccccHHHccccccccccHHHHHHcccccEEEcccEEcccccccccccHHHcccccccEEccccEEEccccccccccccccccccccEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEccccHHHHccccEEEccccccccccccccccccccccEEEEEccccccEEEccccccccccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEcccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEEcccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccccccccc //