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Homo sapiens (cDNA) (huge0)
Gene : KIAA0094
DDBJ      :             KIAA0094
Swiss-Prot:AMPM1_HUMAN  RecName: Full=Methionine aminopeptidase 1;         Short=MetAP 1;         Short=MAP 1;         EC=3.4.11.18;AltName: Full=Peptidase M 1;

Homologs  Archaea  48/68 : Bacteria  907/915 : Eukaryota  195/199 : Viruses  0/175   --->[See Alignment]
d.127.1g.85.1
:394 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   89->392 2b3lA PDBj 0.0 100.0 %
:RPS:PDB   8->64 2danA PDBj 1e-06 26.9 %
:RPS:PDB   89->392 2b3hA PDBj 2e-80 100.0 %
:RPS:SCOP  15->57 2dj8A1  g.85.1.1 * 1e-05 25.0 %
:RPS:SCOP  105->384 1b59A2  d.127.1.1 * 2e-71 25.5 %
:HMM:SCOP  85->385 1b6aA2 d.127.1.1 * 1.7e-87 37.8 %
:RPS:PFM   147->343 PF00557 * Peptidase_M24 1e-25 38.5 %
:HMM:PFM   145->373 PF00557 * Peptidase_M24 2e-49 31.2 202/203  
:HMM:PFM   17->57 PF01753 * zf-MYND 4e-06 39.4 33/40  
:BLT:SWISS 9->394 AMPM1_HUMAN 0.0 100.0 %
:PROS 299->317|PS00680|MAP_1

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0094 GT:ORG huge0 GT:GENE KIAA0094 GT:PRODUCT KIAA0094 GT:DATABASE huge2038 LENGTH 394 SQ:AASEQ ALFQRAGSMAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMSQF SW:ID AMPM1_HUMAN SW:DE RecName: Full=Methionine aminopeptidase 1; Short=MetAP 1; Short=MAP 1; EC=3.4.11.18;AltName: Full=Peptidase M 1; SW:GN Name=METAP1; Synonyms=KIAA0094; SW:KW 3D-structure; Aminopeptidase; Cobalt; Complete proteome; Hydrolase;Metal-binding; Phosphoprotein; Protease. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 9->394|AMPM1_HUMAN|0.0|100.0|386/386| GO:SWS:NREP 4 GO:SWS GO:0004177|"GO:aminopeptidase activity"|Aminopeptidase| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0008233|"GO:peptidase activity"|Protease| PROS 299->317|PS00680|MAP_1|PDOC00575| BL:PDB:NREP 1 BL:PDB:REP 89->392|2b3lA|0.0|100.0|304/305| RP:PDB:NREP 2 RP:PDB:REP 8->64|2danA|1e-06|26.9|52/60| RP:PDB:REP 89->392|2b3hA|2e-80|100.0|304/304| RP:PFM:NREP 1 RP:PFM:REP 147->343|PF00557|1e-25|38.5|187/203|Peptidase_M24| HM:PFM:NREP 2 HM:PFM:REP 145->373|PF00557|2e-49|31.2|202/203|Peptidase_M24| HM:PFM:REP 17->57|PF01753|4e-06|39.4|33/40|zf-MYND| GO:PFM:NREP 1 GO:PFM GO:0009987|"GO:cellular process"|PF00557|IPR000994| RP:SCP:NREP 2 RP:SCP:REP 15->57|2dj8A1|1e-05|25.0|36/47|g.85.1.1| RP:SCP:REP 105->384|1b59A2|2e-71|25.5|263/281|d.127.1.1| HM:SCP:REP 85->385|1b6aA2|1.7e-87|37.8|283/296|d.127.1.1|1/1|Creatinase/aminopeptidase| OP:NHOMO 2027 OP:NHOMOORG 1150 OP:PATTERN 111-112112222221122121-1---1-1-1--111---1--11-11-11-1-22222231111-1- 1221322244422232222-23332422222244444343121332323223433224113332424333211111111122121111222212111--1121113222211111111111111311121112122222121113312312222211111111231222221111111111111312211112366666666466666643444466744444433222237333333333333333332232312223221111122331212223331122111222122111111111111111111111332111333123223333333323224223333321113221122232322222212211321111211111112111111112111111111112-222221221121222222222222212221131111111111111111111112111111122111111111111111111111111211111112223222222222222222222231111111111111122123112112112111111111111122222322211311122222212214323222111-1111111111111111111111111111121121211111112222111211121-1111111111111111211111111111-11111111111111111112221121211111111111111112111111111222222211222111111111222211312111111111111111222222211111222222222122212221111111111111111111111112221211111111111132211111111111111111112-22222111112211221112222211111111 3311233-511-2221111322122222211111111111111111111111111111111111111111111111111111111111-14212322222211333-25132332422223222442223C212242222322422222121231222211122221223311232224X3232275751542463344 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 381 STR:RPRED 96.7 SQ:SECSTR #######ccccccccccccccccccccEEcTTT#####cccEHHccccTTTcHHHHHHHHHHHHHHccEEEEcTTcccccHHHHHHHHccccccccccccccccccccTTccccGGGGcTTcccHHHHHTTTccccccccHHHHHHHHHHHHHHHHHHHHHHHTccTTccHHHHHHHHHHHHHHTTcEETTTTGGGcccccEEEETTEEEccccccccccTTcEEEEEEEEEETTEEEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHTccTTccTTHHHHHHHHHHHHTTcEEcccccEEEccccccEEEEEcccccccccccccTTcEEEEccEEEcccccEEEcTTcccEEETTcccEEEccEEEEEccccEEETTccccccccGGGcc# DISOP:02AL 1-7,58-73| PSIPRED ccccccccccHHHHccccccccccccEEEccHHHHcccccEEEccccHHHHccHHHHHHHcccccccccccccccEEccccccccccccccccccccccccccccccHHHcccccccccccccccHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHccEEccccccccccEEccccccccccccccccccccccEEEEEEEEEEccEEEEEEEEEEcccccHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHccccEEEcccccccccccccccccccccccccccEEccccEEEEcccEEcccccEEEcccccEEEEEccccEEEEEEEEEEcccccEEccccccccHHHHHHcc //