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Homo sapiens (cDNA) (huge0)
Gene : KIAA0287
DDBJ      :             KIAA0287
Swiss-Prot:PEG3_HUMAN   RecName: Full=Paternally-expressed gene 3 protein;AltName: Full=Zinc finger and SCAN domain-containing protein 24;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  90/199 : Viruses  0/175   --->[See Alignment]
a.28.3b.40.4b.8.1d.52.6f.4.3g.37.1g.41.3g.44.1
:1523 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->57 1y7qA PDBj 2e-10 49.0 %
:BLT:PDB   386->527 2i13B PDBj 3e-18 33.6 %
:BLT:PDB   560->702 2i13B PDBj 1e-13 28.7 %
:BLT:PDB   894->1120 2i13A PDBj 2e-12 25.1 %
:BLT:PDB   1042->1182 2i13A PDBj 9e-17 31.2 %
:BLT:PDB   1169->1289 2i13A PDBj 6e-10 32.8 %
:BLT:PDB   1440->1523 2i13B PDBj 2e-06 31.0 %
:RPS:PDB   386->412 1ardA PDBj 2e-04 33.3 %
:RPS:PDB   405->676 1ej6C PDBj 5e-18 12.9 %
:RPS:PDB   775->1122 1ej6C PDBj 5e-15 9.2 %
:RPS:PDB   1093->1182 2b7rA PDBj 7e-09 11.1 %
:RPS:PDB   1204->1289 2dhmA PDBj 2e-07 9.7 %
:RPS:PDB   1440->1523 1ej6C PDBj 3e-06 14.0 %
:RPS:SCOP  7->62 1y7qA1  a.28.3.2 * 1e-17 44.6 %
:RPS:SCOP  152->228 1kmoA  f.4.3.3 * 1e-04 27.3 %
:RPS:SCOP  375->459 1vd4A  g.41.3.1 * 7e-06 8.2 %
:RPS:SCOP  433->642 1k2fA  b.8.1.2 * 3e-15 10.6 %
:RPS:SCOP  857->931 1ny8A  d.52.6.1 * 8e-05 9.3 %
:RPS:SCOP  904->931 2eppA1  g.37.1.1 * 4e-07 25.0 %
:RPS:SCOP  904->994 2g43A1  g.44.1.5 * 1e-04 6.2 %
:RPS:SCOP  1042->1227 1l1oC  b.40.4.3 * 7e-11 6.6 %
:RPS:SCOP  1204->1285 1wirA  g.37.1.5 * 1e-06 10.0 %
:RPS:SCOP  1495->1523 2yrkA1  g.37.1.4 * 2e-05 27.6 %
:HMM:SCOP  7->65 1y7qA1 a.28.3.2 * 7.9e-18 45.8 %
:HMM:SCOP  375->412 2cotA2 g.37.1.1 * 5.9e-08 44.7 %
:HMM:SCOP  420->475 1x3cA1 g.37.1.1 * 1.8e-07 23.2 %
:HMM:SCOP  486->523 2cotA2 g.37.1.1 * 2.2e-07 42.1 %
:HMM:SCOP  542->601 1x3cA1 g.37.1.1 * 1.1e-10 37.9 %
:HMM:SCOP  628->685 1x3cA1 g.37.1.1 * 4.1e-07 31.0 %
:HMM:SCOP  896->931 1x6hA2 g.37.1.1 * 9.7e-07 41.7 %
:HMM:SCOP  1005->1065 1yujA_ g.37.1.1 * 0.00041 25.0 %
:HMM:SCOP  1040->1120 2cshA1 g.37.1.1 * 8.8e-13 43.4 %
:HMM:SCOP  1158->1239 2cshA1 g.37.1.1 * 6.4e-10 34.0 %
:HMM:SCOP  1265->1462 2cshA1 g.37.1.1 * 6.2e-10 34.0 %
:HMM:SCOP  1487->1524 2cotA2 g.37.1.1 * 2.9e-06 39.5 %
:RPS:PFM   7->63 PF02023 * SCAN 4e-13 52.6 %
:HMM:PFM   387->409 PF00096 * zf-C2H2 9.6e-06 43.5 23/23  
:HMM:PFM   440->462 PF00096 * zf-C2H2 3.7e-06 34.8 23/23  
:HMM:PFM   498->520 PF00096 * zf-C2H2 5.1e-05 34.8 23/23  
:HMM:PFM   562->584 PF00096 * zf-C2H2 4.1e-06 39.1 23/23  
:HMM:PFM   904->926 PF00096 * zf-C2H2 2.4e-07 39.1 23/23  
:HMM:PFM   1042->1064 PF00096 * zf-C2H2 2.2e-05 39.1 23/23  
:HMM:PFM   1098->1120 PF00096 * zf-C2H2 8e-07 52.2 23/23  
:HMM:PFM   1161->1182 PF00096 * zf-C2H2 1.8e-05 40.9 22/23  
:HMM:PFM   1217->1239 PF00096 * zf-C2H2 5.1e-05 34.8 23/23  
:HMM:PFM   1267->1289 PF00096 * zf-C2H2 1.4e-06 47.8 23/23  
:HMM:PFM   1440->1462 PF00096 * zf-C2H2 4.8e-05 30.4 23/23  
:HMM:PFM   1499->1521 PF00096 * zf-C2H2 2.5e-05 34.8 23/23  
:HMM:PFM   6->65 PF02023 * SCAN 3.6e-23 48.3 60/96  
:BLT:SWISS 7->1523 PEG3_HUMAN 0.0 99.8 %
:PROS 389->409|PS00028|ZINC_FINGER_C2H2_1
:PROS 442->462|PS00028|ZINC_FINGER_C2H2_1
:PROS 500->520|PS00028|ZINC_FINGER_C2H2_1
:PROS 564->584|PS00028|ZINC_FINGER_C2H2_1
:PROS 906->926|PS00028|ZINC_FINGER_C2H2_1
:PROS 1044->1064|PS00028|ZINC_FINGER_C2H2_1
:PROS 1100->1120|PS00028|ZINC_FINGER_C2H2_1
:PROS 1162->1182|PS00028|ZINC_FINGER_C2H2_1
:PROS 1219->1239|PS00028|ZINC_FINGER_C2H2_1
:PROS 1269->1289|PS00028|ZINC_FINGER_C2H2_1
:PROS 1442->1462|PS00028|ZINC_FINGER_C2H2_1
:PROS 1501->1521|PS00028|ZINC_FINGER_C2H2_1
:REPEAT 9|416->462|469->520|535->584|761->811|878->926|1015->1064|1071->1120|1189->1239|1242->1289
:REPEAT 2|375->415|664->704
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0287 GT:ORG huge0 GT:GENE KIAA0287 GT:PRODUCT KIAA0287 GT:DATABASE huge2038 LENGTH 1523 SQ:AASEQ VQTLGGWVQPETRTKEEIIELLVLEQYLTIIPEKLKPWVRAKKPENCEKLVTLLENYKEMYQPEDDNNSDVTSDDDMTRNRRESSPPHSVHSFSGDRDWDRRGRSRDMEPRDRWSHTRNPRSRMPPRDLSLPVVAKTSFEMDREDDRDSRAYESRSQDAESYQNVVDLAEDRKPHNTIQDNMENYRKLLSLGVQLAEDDGHSHMTQGHSSRSKRSAYPSTSRGLKTMPEAKKSTHRRGICEDESSHGVIMEKFIKDVSRSSKSGRARESSDRSQRFPRMSDDNWKDISLNKRESVIQQRVYEGNAFRGGFRFNSTLVSRKRVLERKRRYHFDTDGKGSIHDQKGCPRKKPFECGSEMRKAMSVSSLSSLSSPSFTESQPIDFGAMPYVCDECGRSFSVISEFVEHQIMHTRENLYEYGESFIHSVAVSEVQKSQVGGKRFECKDCGETFNKSAALAEHRKIHARGYLVECKNQECEEAFMPSPTFSELQKIYGKDKFYECRVCKETFLHSSALIEHQKIHFGDDKDNEREHERERERERGETFRPSPALNEFQKMYGKEKMYECKVCGETFLHSSSLKEHQKIHTRGNPFENKGKVCEETFIPGQSLKRRQKTYNKEKLCDFTDGRDAFMQSSELSEHQKIHSRKNLFEGRGYEKSVIHSGPFTESQKSHTITRPLESDEDEKAFTISSNPYENQKIPTKENVYEAKSYERSVIHSLASVEAQKSHSVAGPSKPKVMAESTIQSFDAINHQRVRAGGNTSEGREYSRSVIHSLVASKPPRSHNGNELVESNEKGESSIYISDLNDKRQKIPARENPCEGGSKNRNYEDSVIQSVFRAKPQKSVPGEGSGEFKKDGEFSVPSSNVREYQKARAKKKYIEHRSNETSVIHSLPFGEQTFRPRGMLYECQECGECFAHSSDLTEHQKIHDREKPSGSRNYEWSVIRSLAPTDPQTSYAQEQYAKEQARNKCKDFRQFFATSEDLNTNQKIYDQEKSHGEESQGENTDGEETHSEETHGQETIEDPVIQGSDMEDPQKDDPDDKIYECEDCGLGFVDLTDLTDHQKVHSRKCLVDSREYTHSVIHTHSISEYQRDYTGEQLYECPKCGESFIHSSFLFEHQRIHEQDQLYSMKGCDDGFIALLPMKPRRNRAAERNPALAGSAIRCLLCGQGFIHSSALNEHMRLHREDDLLEQSQMAEEAIIPGLALTEFQRSQTEERLFECAVCGESFVNPAELADHVTVHKNEPYEYGSSYTHTSFLTEPLKGAIPFYECKDCGKSFIHSTVLTKHKELHLEEEEEDEAAAAAAAAAQEVEANVHVPQVVLRIQGLNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPNGEAEQPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQEIQVEEPYYDCHECTETFTSSTAFSEHLKTHASMIIFEPANAFGECSGYIERASTSTGGANQADEKYFKCDVCGQLFNDRLSLARHQNTHTG SW:ID PEG3_HUMAN SW:DE RecName: Full=Paternally-expressed gene 3 protein;AltName: Full=Zinc finger and SCAN domain-containing protein 24; SW:GN Name=PEG3; Synonyms=KIAA0287, ZSCAN24; SW:KW Alternative splicing; Apoptosis; Complete proteome; Cytoplasm;Metal-binding; Nucleus; Polymorphism; Repeat; Zinc; Zinc-finger. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 7->1523|PEG3_HUMAN|0.0|99.8|1515/1588| GO:SWS:NREP 4 GO:SWS GO:0006915|"GO:apoptosis"|Apoptosis| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| PROS 389->409|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 442->462|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 500->520|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 564->584|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 906->926|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 1044->1064|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 1100->1120|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 1162->1182|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 1219->1239|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 1269->1289|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 1442->1462|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 1501->1521|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| NREPEAT 2 REPEAT 9|416->462|469->520|535->584|761->811|878->926|1015->1064|1071->1120|1189->1239|1242->1289| REPEAT 2|375->415|664->704| SEG 65->76|ddnnsdvtsddd| SEG 94->107|sgdrdwdrrgrsrd| SEG 362->373|svsslsslssps| SEG 528->541|erehererererge| SEG 1031->1040|dpqkddpddk| SEG 1143->1156|prrnraaernpala| SEG 1291->1311|eeeeedeaaaaaaaaaqevea| SEG 1327->1372|veaaepeveaaepeveaaepeveaaepngeaegpdgeaaepigeag| SEG 1391->1419|agiedpeeraeepegkaeepegdadepdg| SEG 1426->1437|eegedqeiqvee| SEG 1446->1457|tetftsstafse| BL:PDB:NREP 7 BL:PDB:REP 7->57|1y7qA|2e-10|49.0|51/98| BL:PDB:REP 386->527|2i13B|3e-18|33.6|140/144| BL:PDB:REP 560->702|2i13B|1e-13|28.7|141/144| BL:PDB:REP 894->1120|2i13A|2e-12|25.1|141/151| BL:PDB:REP 1042->1182|2i13A|9e-17|31.2|135/151| BL:PDB:REP 1169->1289|2i13A|6e-10|32.8|116/151| BL:PDB:REP 1440->1523|2i13B|2e-06|31.0|78/144| RP:PDB:NREP 6 RP:PDB:REP 386->412|1ardA|2e-04|33.3|27/29| RP:PDB:REP 405->676|1ej6C|5e-18|12.9|241/1221| RP:PDB:REP 775->1122|1ej6C|5e-15|9.2|317/1221| RP:PDB:REP 1093->1182|2b7rA|7e-09|11.1|85/568| RP:PDB:REP 1204->1289|2dhmA|2e-07|9.7|86/107| RP:PDB:REP 1440->1523|1ej6C|3e-06|14.0|84/1221| RP:PFM:NREP 1 RP:PFM:REP 7->63|PF02023|4e-13|52.6|57/96|SCAN| HM:PFM:NREP 13 HM:PFM:REP 387->409|PF00096|9.6e-06|43.5|23/23|zf-C2H2| HM:PFM:REP 440->462|PF00096|3.7e-06|34.8|23/23|zf-C2H2| HM:PFM:REP 498->520|PF00096|5.1e-05|34.8|23/23|zf-C2H2| HM:PFM:REP 562->584|PF00096|4.1e-06|39.1|23/23|zf-C2H2| HM:PFM:REP 904->926|PF00096|2.4e-07|39.1|23/23|zf-C2H2| HM:PFM:REP 1042->1064|PF00096|2.2e-05|39.1|23/23|zf-C2H2| HM:PFM:REP 1098->1120|PF00096|8e-07|52.2|23/23|zf-C2H2| HM:PFM:REP 1161->1182|PF00096|1.8e-05|40.9|22/23|zf-C2H2| HM:PFM:REP 1217->1239|PF00096|5.1e-05|34.8|23/23|zf-C2H2| HM:PFM:REP 1267->1289|PF00096|1.4e-06|47.8|23/23|zf-C2H2| HM:PFM:REP 1440->1462|PF00096|4.8e-05|30.4|23/23|zf-C2H2| HM:PFM:REP 1499->1521|PF00096|2.5e-05|34.8|23/23|zf-C2H2| HM:PFM:REP 6->65|PF02023|3.6e-23|48.3|60/96|SCAN| GO:PFM:NREP 3 GO:PFM GO:0003700|"GO:transcription factor activity"|PF02023|IPR003309| GO:PFM GO:0005634|"GO:nucleus"|PF02023|IPR003309| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF02023|IPR003309| RP:SCP:NREP 10 RP:SCP:REP 7->62|1y7qA1|1e-17|44.6|56/96|a.28.3.2| RP:SCP:REP 152->228|1kmoA|1e-04|27.3|77/661|f.4.3.3| RP:SCP:REP 375->459|1vd4A|7e-06|8.2|57/62|g.41.3.1| RP:SCP:REP 433->642|1k2fA|3e-15|10.6|188/190|b.8.1.2| RP:SCP:REP 857->931|1ny8A|8e-05|9.3|75/97|d.52.6.1| RP:SCP:REP 904->931|2eppA1|4e-07|25.0|28/53|g.37.1.1| RP:SCP:REP 904->994|2g43A1|1e-04|6.2|90/117|g.44.1.5| RP:SCP:REP 1042->1227|1l1oC|7e-11|6.6|137/173|b.40.4.3| RP:SCP:REP 1204->1285|1wirA|1e-06|10.0|81/121|g.37.1.5| RP:SCP:REP 1495->1523|2yrkA1|2e-05|27.6|29/48|g.37.1.4| HM:SCP:REP 7->65|1y7qA1|7.9e-18|45.8|59/0|a.28.3.2|1/1|Retrovirus capsid dimerization domain-like| HM:SCP:REP 375->412|2cotA2|5.9e-08|44.7|38/0|g.37.1.1|1/15|C2H2 and C2HC zinc fingers| HM:SCP:REP 420->475|1x3cA1|1.8e-07|23.2|56/0|g.37.1.1|2/14|C2H2 and C2HC zinc fingers| HM:SCP:REP 486->523|2cotA2|2.2e-07|42.1|38/0|g.37.1.1|3/15|C2H2 and C2HC zinc fingers| HM:SCP:REP 542->601|1x3cA1|1.1e-10|37.9|58/0|g.37.1.1|4/14|C2H2 and C2HC zinc fingers| HM:SCP:REP 628->685|1x3cA1|4.1e-07|31.0|58/0|g.37.1.1|5/14|C2H2 and C2HC zinc fingers| HM:SCP:REP 896->931|1x6hA2|9.7e-07|41.7|36/0|g.37.1.1|7/15|C2H2 and C2HC zinc fingers| HM:SCP:REP 1005->1065|1yujA_|0.00041|25.0|48/54|g.37.1.1|8/14|C2H2 and C2HC zinc fingers| HM:SCP:REP 1040->1120|2cshA1|8.8e-13|43.4|53/0|g.37.1.1|8/11|C2H2 and C2HC zinc fingers| HM:SCP:REP 1158->1239|2cshA1|6.4e-10|34.0|53/0|g.37.1.1|9/11|C2H2 and C2HC zinc fingers| HM:SCP:REP 1265->1462|2cshA1|6.2e-10|34.0|53/0|g.37.1.1|10/11|C2H2 and C2HC zinc fingers| HM:SCP:REP 1487->1524|2cotA2|2.9e-06|39.5|38/0|g.37.1.1|15/15|C2H2 and C2HC zinc fingers| OP:NHOMO 20886 OP:NHOMOORG 90 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------11------1----------------------------1----11-112221-1-----1--1--1--11---1---------1-----1--21---1-**********************o**************************eq*S**SO*w**35*8--------------1--------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1035 STR:RPRED 68.0 SQ:SECSTR ######HHccccccHHHHHHHHHHHHHHHHccTHHHHHHHTcccccHHHHHHHHHHHT###########################################################################################################################################################################################################################################################################################################################cccTTcEEETHHHHHHHHHcHHHHTcTcccGccTTcccTTcccccccccHHHHHHHHHHHHHHHHHHHTTcccccccccccccccTTcccccTTcHcTTcccTTccHHHHHHHHHTTccccccccccTTTccccccHHHHHHHHGGGTccccccTTEEEEEEEccccccEEEEETTcccEEEcccccccccEEccccccEEEEEEEcccccccccGGGGHHcccEEEEcccHHHHHTTEEEEccHHHHHHHHHHHcccccccEEEEEEcTTcccccccccccccHccccTTccccGGGGccccHHHHHHHHTcccHcHHHHHHHHHccEEEHHHHHHHHHHHHHHHHHHHTcTTcTTccccccccHHHHHHHTTccHHHHHHH##################ccccccccTTccccccccccccHHHHHHHHHHHHcccccccTTcccTTcccccccccHHHHHHHHHHHHHHHHHHHTTcccccccccccccTTcccccTTccTTcccTTccHHHHHHHHHTTcEETTcTcccTTTccccccHHHHHHHHHHHccccTccccTTTGGGcccHHHHHHHHHTTcccccTTHHHHHHHHTcccccTTcEEEEEcTTcTTEEEEEEEEEEETTEEEEEEcccccEEEETTcTTETTHHHHHTcEEcccccGGGccccccccEEEEccccccEEEcccHHHHHHHHHHHccEEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHccccccEEEEEETTETccGGGcccGGGTEEcccEEEEEccccccTTEEEEEEEEEEcccccEEEEEccccccEETTEETHHHHHHHHHHTTcEEEEEEEEcccHHHHHHHHHHHHHHHHHHHcccEEETTTccccccccTTccEEETTEHHHHEEcTTTHHHHHcccccccccccccc#####################################################################################################################################################cccTTTccccccHHHHHHHHGGGcccccTTEEEEEEcccccEEEEETTccccTTccccccccEEccccccEEEEEEEccccccc DISOP:02AL 1-2,59-126,263-263,265-269,280-288,290-294,1521-1524| PSIPRED ccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccEEccccccEEccccccccccEEcccccEEEEEEcccEEEEEEEcccHHccccccHHHHccccccccccEEHHHcccccccccccEEcccccccccccccccccEEEcccccccccEEcHHHHccccccccccccEEccccccccccccccccccccEEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEccccccccccccccccccccEEccHHccHHccccccccccccccEEEEEccccccEEEcccccEEcccccccEEEEEcccccccccccEEcccccccEEEEEccccccEEEccccccccccccccEEEEEccccccEEEcccccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccccccccccEEEccccccccccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccccccccccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEccccEEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccccccccccEEcccccccEEEEEccccccEEEcccccEEEEcccccccEEEccccccEEEcccccEEcccccccEEEEEEccccccEEEcccccccccccccEEEEEEEEEEccccccEEEcccccEEcccccccEEEEEcccccccccccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccccccccccEEEEcccccccEEEEcccccccccccEEEcccccEEcccccccEEEEEccccccccccccccccccccccccccccccccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEEccccccccccccEEEcccccEEcccccccEEEEEccccccEEEcHHHccHHcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccccccEEEEcccccccEEcccccEEEcccccEEcccccccEEEEEccccccEEEccHHHHHHHcccEEHHccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEccccccccccccccEEEEcccccccEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccccccHHHcccccEEEEEEccccEEEEcccccEEEcccccEEcccccccEEEEcccc //