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Homo sapiens (cDNA) (huge0)
Gene : KIAA0474
DDBJ      :             KIAA0474
Swiss-Prot:RPGP1_HUMAN  RecName: Full=Rap1 GTPase-activating protein 1;         Short=Rap1GAP1;         Short=Rap1GAP;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  147/199 : Viruses  0/175   --->[See Alignment]
d.17.4e.55.1
:782 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   179->515 3brwB PDBj 0.0 99.4 %
:RPS:PDB   179->515 3brwB PDBj e-125 99.4 %
:RPS:SCOP  179->514 1srqA  e.55.1.1 * e-142 99.4 %
:RPS:SCOP  566->631 2rfrA1  d.17.4.28 * 7e-04 31.2 %
:HMM:SCOP  179->514 1srqA_ e.55.1.1 * 3.5e-125 46.1 %
:RPS:PFM   98->117 PF02188 * GoLoco 7e-04 55.0 %
:RPS:PFM   311->494 PF02145 * Rap_GAP 9e-41 50.3 %
:RPS:PFM   607->688 PF10310 * DUF2413 8e-04 28.0 %
:HMM:PFM   311->497 PF02145 * Rap_GAP 1.4e-64 43.8 185/188  
:HMM:PFM   98->118 PF02188 * GoLoco 5.5e-13 47.6 21/23  
:BLT:SWISS 102->782 RPGP1_HUMAN 0.0 97.9 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0474 GT:ORG huge0 GT:GENE KIAA0474 GT:PRODUCT KIAA0474 GT:DATABASE huge2038 LENGTH 782 SQ:AASEQ RAPECRAQDAPGPGPWVNTSANRGHPPSDPHSEEADPSSNSDIATEQPYNFWVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSYTPSLYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDPACPEIKIQLEASEQHMPQLGC SW:ID RPGP1_HUMAN SW:DE RecName: Full=Rap1 GTPase-activating protein 1; Short=Rap1GAP1; Short=Rap1GAP; SW:GN Name=RAP1GAP; Synonyms=KIAA0474, RAP1GA1; SW:KW 3D-structure; Acetylation; Alternative splicing; Complete proteome;Golgi apparatus; GTPase activation; Membrane; Phosphoprotein;Polymorphism. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 102->782|RPGP1_HUMAN|0.0|97.9|655/663| GO:SWS:NREP 3 GO:SWS GO:0005794|"GO:Golgi apparatus"|Golgi apparatus| GO:SWS GO:0005096|"GO:GTPase activator activity"|GTPase activation| GO:SWS GO:0016020|"GO:membrane"|Membrane| SEG 522->532|gsggggffesf| SEG 692->718|fsrssssassfasvveetegvdgedtg| BL:PDB:NREP 1 BL:PDB:REP 179->515|3brwB|0.0|99.4|337/337| RP:PDB:NREP 1 RP:PDB:REP 179->515|3brwB|e-125|99.4|337/337| RP:PFM:NREP 3 RP:PFM:REP 98->117|PF02188|7e-04|55.0|20/22|GoLoco| RP:PFM:REP 311->494|PF02145|9e-41|50.3|179/182|Rap_GAP| RP:PFM:REP 607->688|PF10310|8e-04|28.0|82/434|DUF2413| HM:PFM:NREP 2 HM:PFM:REP 311->497|PF02145|1.4e-64|43.8|185/188|Rap_GAP| HM:PFM:REP 98->118|PF02188|5.5e-13|47.6|21/23|GoLoco| GO:PFM:NREP 5 GO:PFM GO:0005096|"GO:GTPase activator activity"|PF02188|IPR003109| GO:PFM GO:0007165|"GO:signal transduction"|PF02188|IPR003109| GO:PFM GO:0005096|"GO:GTPase activator activity"|PF02145|IPR000331| GO:PFM GO:0005622|"GO:intracellular"|PF02145|IPR000331| GO:PFM GO:0051056|"GO:regulation of small GTPase mediated signal transduction"|PF02145|IPR000331| RP:SCP:NREP 2 RP:SCP:REP 179->514|1srqA|e-142|99.4|330/330|e.55.1.1| RP:SCP:REP 566->631|2rfrA1|7e-04|31.2|64/153|d.17.4.28| HM:SCP:REP 179->514|1srqA_|3.5e-125|46.1|336/336|e.55.1.1|1/1|Rap/Ran-GAP| OP:NHOMO 910 OP:NHOMOORG 147 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----9A3-----4441111111111111111-11111111-111111111111111111111111--1----11------1-1---11-11111111--1111555-C-2DEGDKFJ98769A9YO7N7f*E6ODL6796D79DA59866D77I9C9B936834573667B2455--------------1----12-1- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 339 STR:RPRED 43.4 SQ:SECSTR ################################################################################################################################################################################cccccccccGGGGHHHHHTTTcccEEEEEEETTTEEEEEEEEEEEETTEEEEEEEEEccccEEEEccccccccccccHHHHHHHHcTTccccccEEcccTTHHHHHHHHHTcccccEEEEEEEEEcTTcccHHHHHccccccTTHHHHHHHHcEEEEcTTcccccTTccccccccccEEEEEccTTcEEEEEETTTccccTTcTTcHHHHHHHTTccEEEEEEcccccccGGGcccccccEEEEEEcccccccccEEEEEEEEcccccccccccccccEEETTHHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHHHHHHHHHHHHHHHHHHTTcccccc########################################################################################################################################################################################################################################################################### DISOP:02AL 1-9,22-47,56-88,90-91,115-115,118-118,161-179,507-574,591-592,598-598,603-709,715-731,738-760,776-783| PSIPRED ccccccccccccccccccccccccccccccccccccHHHHHHHHccccccccEEccccHHHHHccccccccccccccccccccccccccccccccHHHHHHHHHHHHcccccHHHccccccccccccccccccHHHHHcccccccEEEcccccccEEEccccccccccccccccccccEEEEEEcccccEEHHccccccccccEEcccccccEEEEEEEEEccccccEEEEEEEcccccEEEEccccccccccHHHHHHHHHHHcccccccccccHHHHHHHHHcccccccccccEEEEEEccccccHHHHHccccccHHHHHHHHHcccEEEEcccccccccccccccccccEEEEEEEccEEEEEEEEcccccccccccEEcccccccccEEEEEEccccccccccccccccccEEEEEEEccccccccEEEEEEEEcccccccccccccccEEccccccHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHcHHHHccccccccccccccccccccccccccccccccHHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccEEcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHccccccccccEEEEEHHHHHHHHHccc //