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Homo sapiens (cDNA) (huge0)
Gene : KIAA0835
DDBJ      :             KIAA0835
Swiss-Prot:MYT1_HUMAN   RecName: Full=Myelin transcription factor 1;         Short=MyT1;         Short=MyTI;AltName: Full=Proteolipid protein-binding protein;AltName: Full=PLPB1;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  64/199 : Viruses  0/175   --->[See Alignment]
a.47.2g.73.1
:1167 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   71->108 2jydA PDBj 2e-11 65.8 %
:BLT:PDB   484->531 1pxeA PDBj 8e-26 95.8 %
:BLT:PDB   523->559 2jydA PDBj 6e-10 62.2 %
:BLT:PDB   844->876 2jydA PDBj 4e-14 90.9 %
:BLT:PDB   881->924 2jydA PDBj 7e-22 95.5 %
:BLT:PDB   934->1017 2cs8A PDBj 1e-32 73.5 %
:RPS:PDB   478->559 2cs8A PDBj 2e-04 42.9 %
:RPS:PDB   938->1029 2cs8A PDBj 1e-04 68.5 %
:RPS:SCOP  76->103 1pxeA  g.73.1.1 * 6e-09 64.3 %
:RPS:SCOP  484->531 1pxeA  g.73.1.1 * 1e-14 95.8 %
:RPS:SCOP  842->889 1pxeA  g.73.1.1 * 4e-13 54.2 %
:RPS:SCOP  889->930 1pxeA  g.73.1.1 * 2e-11 52.4 %
:RPS:SCOP  935->972 1pxeA  g.73.1.1 * 1e-09 52.6 %
:RPS:SCOP  988->1034 1pxeA  g.73.1.1 * 2e-12 44.7 %
:RPS:SCOP  1041->1078 1dn1B  a.47.2.1 * 7e-04 29.7 %
:HMM:SCOP  72->119 1pxeA_ g.73.1.1 * 3.6e-12 50.0 %
:HMM:SCOP  484->531 1pxeA_ g.73.1.1 * 2.4e-14 60.4 %
:HMM:SCOP  532->575 1pxeA_ g.73.1.1 * 1.4e-09 45.5 %
:HMM:SCOP  842->885 1pxeA_ g.73.1.1 * 4e-13 65.9 %
:HMM:SCOP  886->933 1pxeA_ g.73.1.1 * 6.9e-14 58.3 %
:HMM:SCOP  935->982 1pxeA_ g.73.1.1 * 3.5e-12 56.2 %
:HMM:SCOP  988->1035 1pxeA_ g.73.1.1 * 2e-12 54.2 %
:RPS:PFM   74->103 PF01530 * zf-C2HC 8e-09 76.7 %
:RPS:PFM   486->513 PF01530 * zf-C2HC 2e-09 82.1 %
:RPS:PFM   530->559 PF01530 * zf-C2HC 5e-08 70.0 %
:RPS:PFM   606->834 PF08474 * MYT1 2e-52 67.6 %
:RPS:PFM   844->873 PF01530 * zf-C2HC 8e-11 86.7 %
:RPS:PFM   888->917 PF01530 * zf-C2HC 8e-11 86.7 %
:RPS:PFM   937->966 PF01530 * zf-C2HC 1e-08 73.3 %
:RPS:PFM   992->1019 PF01530 * zf-C2HC 2e-08 75.0 %
:HMM:PFM   74->103 PF01530 * zf-C2HC 1.8e-17 73.3 30/31  
:HMM:PFM   486->514 PF01530 * zf-C2HC 1.7e-16 72.4 29/31  
:HMM:PFM   530->559 PF01530 * zf-C2HC 1.1e-17 70.0 30/31  
:HMM:PFM   845->873 PF01530 * zf-C2HC 6.6e-19 79.3 29/31  
:HMM:PFM   888->917 PF01530 * zf-C2HC 3.4e-19 80.0 30/31  
:HMM:PFM   937->966 PF01530 * zf-C2HC 7.5e-18 70.0 30/31  
:HMM:PFM   991->1019 PF01530 * zf-C2HC 5.9e-16 75.9 29/31  
:HMM:PFM   606->661 PF08474 * MYT1 1.2e-31 85.7 56/257  
:HMM:PFM   662->814 PF08474 * MYT1 6.6e-75 68.0 147/257  
:HMM:PFM   1058->1111 PF06156 * DUF972 0.00014 27.8 54/107  
:BLT:SWISS 47->1167 MYT1_HUMAN 0.0 100.0 %
:REPEAT 7|74->111|486->523|530->565|843->883|888->925|937->978|985->1027
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0835 GT:ORG huge0 GT:GENE KIAA0835 GT:PRODUCT KIAA0835 GT:DATABASE huge2038 LENGTH 1167 SQ:AASEQ CHFERGQTIAVGKENEFRGELLNQRWTHGGKASSCRTSRHLGRHCKMSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPLDTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV SW:ID MYT1_HUMAN SW:DE RecName: Full=Myelin transcription factor 1; Short=MyT1; Short=MyTI;AltName: Full=Proteolipid protein-binding protein;AltName: Full=PLPB1; SW:GN Name=MYT1; Synonyms=KIAA0835, KIAA1050, MTF1, MYTI, PLPB1; SW:KW Complete proteome; Developmental protein; Differentiation;DNA-binding; Metal-binding; Neurogenesis; Nucleus; Repeat;Transcription; Transcription regulation; Zinc; Zinc-finger. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 47->1167|MYT1_HUMAN|0.0|100.0|1121/1121| GO:SWS:NREP 8 GO:SWS GO:0007275|"GO:multicellular organismal development"|Developmental protein| GO:SWS GO:0030154|"GO:cell differentiation"|Differentiation| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0007399|"GO:nervous system development"|Neurogenesis| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation| NREPEAT 1 REPEAT 7|74->111|486->523|530->565|843->883|888->925|937->978|985->1027| SEG 193->206|gsatasskgsyssy| SEG 246->257|eaaegaaseege| SEG 268->276|eevvevtte| SEG 304->352|eeedeeeeeeeeeeeedeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee| SEG 731->738|sssscsss| SEG 751->769|sstsapsssmtspqssqas| SEG 788->806|eeepeesepaahsfassea| SEG 1082->1100|eknlknieeenklieeqne| BL:PDB:NREP 6 BL:PDB:REP 71->108|2jydA|2e-11|65.8|38/46| BL:PDB:REP 484->531|1pxeA|8e-26|95.8|48/48| BL:PDB:REP 523->559|2jydA|6e-10|62.2|37/46| BL:PDB:REP 844->876|2jydA|4e-14|90.9|33/46| BL:PDB:REP 881->924|2jydA|7e-22|95.5|44/46| BL:PDB:REP 934->1017|2cs8A|1e-32|73.5|83/108| RP:PDB:NREP 2 RP:PDB:REP 478->559|2cs8A|2e-04|42.9|82/108| RP:PDB:REP 938->1029|2cs8A|1e-04|68.5|92/108| RP:PFM:NREP 8 RP:PFM:REP 74->103|PF01530|8e-09|76.7|30/31|zf-C2HC| RP:PFM:REP 486->513|PF01530|2e-09|82.1|28/31|zf-C2HC| RP:PFM:REP 530->559|PF01530|5e-08|70.0|30/31|zf-C2HC| RP:PFM:REP 606->834|PF08474|2e-52|67.6|213/246|MYT1| RP:PFM:REP 844->873|PF01530|8e-11|86.7|30/31|zf-C2HC| RP:PFM:REP 888->917|PF01530|8e-11|86.7|30/31|zf-C2HC| RP:PFM:REP 937->966|PF01530|1e-08|73.3|30/31|zf-C2HC| RP:PFM:REP 992->1019|PF01530|2e-08|75.0|28/31|zf-C2HC| HM:PFM:NREP 10 HM:PFM:REP 74->103|PF01530|1.8e-17|73.3|30/31|zf-C2HC| HM:PFM:REP 486->514|PF01530|1.7e-16|72.4|29/31|zf-C2HC| HM:PFM:REP 530->559|PF01530|1.1e-17|70.0|30/31|zf-C2HC| HM:PFM:REP 845->873|PF01530|6.6e-19|79.3|29/31|zf-C2HC| HM:PFM:REP 888->917|PF01530|3.4e-19|80.0|30/31|zf-C2HC| HM:PFM:REP 937->966|PF01530|7.5e-18|70.0|30/31|zf-C2HC| HM:PFM:REP 991->1019|PF01530|5.9e-16|75.9|29/31|zf-C2HC| HM:PFM:REP 606->661|PF08474|1.2e-31|85.7|56/257|MYT1| HM:PFM:REP 662->814|PF08474|6.6e-75|68.0|147/257|MYT1| HM:PFM:REP 1058->1111|PF06156|0.00014|27.8|54/107|DUF972| GO:PFM:NREP 28 GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| RP:SCP:NREP 7 RP:SCP:REP 76->103|1pxeA|6e-09|64.3|28/48|g.73.1.1| RP:SCP:REP 484->531|1pxeA|1e-14|95.8|48/48|g.73.1.1| RP:SCP:REP 842->889|1pxeA|4e-13|54.2|48/48|g.73.1.1| RP:SCP:REP 889->930|1pxeA|2e-11|52.4|42/48|g.73.1.1| RP:SCP:REP 935->972|1pxeA|1e-09|52.6|38/48|g.73.1.1| RP:SCP:REP 988->1034|1pxeA|2e-12|44.7|47/48|g.73.1.1| RP:SCP:REP 1041->1078|1dn1B|7e-04|29.7|37/222|a.47.2.1| HM:SCP:REP 72->119|1pxeA_|3.6e-12|50.0|48/48|g.73.1.1|1/7|CCHHC domain| HM:SCP:REP 484->531|1pxeA_|2.4e-14|60.4|48/48|g.73.1.1|2/7|CCHHC domain| HM:SCP:REP 532->575|1pxeA_|1.4e-09|45.5|44/48|g.73.1.1|3/7|CCHHC domain| HM:SCP:REP 842->885|1pxeA_|4e-13|65.9|44/48|g.73.1.1|4/7|CCHHC domain| HM:SCP:REP 886->933|1pxeA_|6.9e-14|58.3|48/48|g.73.1.1|5/7|CCHHC domain| HM:SCP:REP 935->982|1pxeA_|3.5e-12|56.2|48/48|g.73.1.1|6/7|CCHHC domain| HM:SCP:REP 988->1035|1pxeA_|2e-12|54.2|48/48|g.73.1.1|7/7|CCHHC domain| OP:NHOMO 291 OP:NHOMOORG 64 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------566774933333449C363GV5573B44445444514442443534644221231111222111------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 305 STR:RPRED 26.1 SQ:SECSTR ################################################################ccccccccccccccTTcccccccccccccccccTTcHHHHHHHcc################################################################################################################################################################################################################################################################################################################################################################################cccccccccccccTTcccccccccccccccccTTcHHHHHHHcccccccccccccccccccccccTTccccccccTTTcHHHH###########################################################################################################################################################################################################################################################################################cccccTTcccccccccccccccccTTcHHHHHHHccTcccTTcTTccccccccccccccccccccccTTTcTTTTcccccc#########cccTccccTTcccccccccccccccccTTcHHHHHHHcccTTcccccccccccccccccccccccccccTTccccccccTTTcHHHHHHccccccc########################################################################################################################################## DISOP:02AL 1-1,23-70,95-208,222-488,519-520,536-553,557-592,648-658,689-708,718-826,857-884,914-936,969-1000,1017-1052| PSIPRED cccccccEEEccccHHHHHHHHHHHHHcccccccccccccccccccccccccccccccccccccccccccHHHHcccccccccccEEEEEcccHHHHHcccHHHHHHHHHHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHccHHHHccccccccHHccccccccccccccccccccccccHHHHccccccccccccccccccccccccHHcccccccccccHHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHcccccccccccccccccHHHcccccccccccccccccHHccccccccccccccccccccccHHHHHHHHccccHHHHHHHHHHHHcccccccccccccccccccccccccccccccccccccccccccccccccEEEccccccccccccccccccccccccccHHHcccHHHHccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHccccccccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHcccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHHHHHHccHHHHHHccccccccccccccccccEEEEcccccccccccccccccccccccccccccccccccccccccccccccHHccccHHHHcccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHHccccccccccccccccccccccccccccccccHHHccccccccccccccccccccccccccccccccccccccccccccccHHHHccccccccccccccccccccccccccccccccccccccccccccccccccHHcccccccccHHHHccccccccccccccHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHcccc //