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Homo sapiens (cDNA) (huge0)
Gene : KIAA0911
DDBJ      :             KIAA0911
Swiss-Prot:CSTN1_HUMAN  RecName: Full=Calsyntenin-1;AltName: Full=Alcadein-alpha;         Short=Alc-alpha;AltName: Full=Alzheimer-related cadherin-like protein;AltName: Full=Non-classical cadherin XB31alpha;Contains:  RecName: Full=Soluble Alc-alpha;           Short=SAlc-alpha;Contains:  RecName: Full=CTF1-alpha;  AltName: Full=C-terminal fragment 1-alpha;Flags: Precursor;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  66/199 : Viruses  0/175   --->[See Alignment]
b.1.6b.120.1b.170.1b.29.1
:1056 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   191->313 1l3wA PDBj 2e-06 31.6 %
:RPS:PDB   183->371 2a74A PDBj 9e-23 10.9 %
:RPS:PDB   431->582 1c4rG PDBj 1e-19 12.8 %
:RPS:SCOP  144->193 2ed6A1  b.170.1.1 * 5e-04 25.0 %
:RPS:SCOP  176->332 1o75A3  b.120.1.1 * 7e-20 16.7 %
:RPS:SCOP  421->638 1epwA1  b.29.1.6 * 6e-18 10.5 %
:HMM:SCOP  106->231 1l3wA3 b.1.6.1 * 5.7e-10 27.8 %
:HMM:SCOP  232->334 1l3wA3 b.1.6.1 * 3.8e-18 28.2 %
:HMM:SCOP  407->637 2erfA1 b.29.1.4 * 6.2e-29 28.4 %
:HMM:PFM   168->229 PF00028 * Cadherin 6.1e-07 29.6 54/93  
:HMM:PFM   244->332 PF00028 * Cadherin 7.5e-11 31.0 87/93  
:HMM:PFM   981->1046 PF02724 * CDC45 6.6e-06 21.9 64/627  
:HMM:PFM   517->583 PF00722 * Glyco_hydro_16 0.00016 25.8 66/185  
:BLT:SWISS 101->1056 CSTN1_HUMAN 0.0 100.0 %
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA0911 GT:ORG huge0 GT:GENE KIAA0911 GT:PRODUCT KIAA0911 GT:DATABASE huge2038 LENGTH 1056 SQ:AASEQ LLPLPSARRCSEAGRAPRPERAAQRHGGGGGGSSLDPRSSPRRGAAGPRPLEPRELRELRSASRAPPCRSRPGLAMLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAESFEVTVTKEGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLEWDDSTLSY SW:ID CSTN1_HUMAN SW:DE RecName: Full=Calsyntenin-1;AltName: Full=Alcadein-alpha; Short=Alc-alpha;AltName: Full=Alzheimer-related cadherin-like protein;AltName: Full=Non-classical cadherin XB31alpha;Contains: RecName: Full=Soluble Alc-alpha; Short=SAlc-alpha;Contains: RecName: Full=CTF1-alpha; AltName: Full=C-terminal fragment 1-alpha;Flags: Precursor; SW:GN Name=CLSTN1; Synonyms=CS1, KIAA0911; SW:KW Alternative splicing; Calcium; Cell adhesion; Cell junction;Cell membrane; Cell projection; Complete proteome;Direct protein sequencing; Endoplasmic reticulum; Glycoprotein;Golgi apparatus; Membrane; Nucleus; Polymorphism;Postsynaptic cell membrane; Repeat; Signal; Synapse; Transmembrane. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 101->1056|CSTN1_HUMAN|0.0|100.0|956/981| GO:SWS:NREP 11 GO:SWS GO:0007155|"GO:cell adhesion"|Cell adhesion| GO:SWS GO:0030054|"GO:cell junction"|Cell junction| GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0042995|"GO:cell projection"|Cell projection| GO:SWS GO:0005783|"GO:endoplasmic reticulum"|Endoplasmic reticulum| GO:SWS GO:0005794|"GO:Golgi apparatus"|Golgi apparatus| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0045211|"GO:postsynaptic membrane"|Postsynaptic cell membrane| GO:SWS GO:0045202|"GO:synapse"|Synapse| GO:SWS GO:0016021|"GO:integral to membrane"|Transmembrane| TM:NTM 1 TM:REGION 929->951| SEG 12->44|eagraprperaaqrhggggggssldprssprrg| SEG 48->100|prpleprelrelrsasrappcrsrpglamlrrpapalapaarlllagllcggg| SEG 665->674|legedlgeld| SEG 929->947|avvpstatvvivvcvsflv| SEG 998->1034|sseeeeeeeeeeesedgeeedditsaesesseeeege| BL:PDB:NREP 1 BL:PDB:REP 191->313|1l3wA|2e-06|31.6|117/540| RP:PDB:NREP 2 RP:PDB:REP 183->371|2a74A|9e-23|10.9|174/630| RP:PDB:REP 431->582|1c4rG|1e-19|12.8|141/182| HM:PFM:NREP 4 HM:PFM:REP 168->229|PF00028|6.1e-07|29.6|54/93|Cadherin| HM:PFM:REP 244->332|PF00028|7.5e-11|31.0|87/93|Cadherin| HM:PFM:REP 981->1046|PF02724|6.6e-06|21.9|64/627|CDC45| HM:PFM:REP 517->583|PF00722|0.00016|25.8|66/185|Glyco_hydro_16| RP:SCP:NREP 3 RP:SCP:REP 144->193|2ed6A1|5e-04|25.0|48/170|b.170.1.1| RP:SCP:REP 176->332|1o75A3|7e-20|16.7|144/191|b.120.1.1| RP:SCP:REP 421->638|1epwA1|6e-18|10.5|190/218|b.29.1.6| HM:SCP:REP 106->231|1l3wA3|5.7e-10|27.8|108/0|b.1.6.1|1/2|Cadherin-like| HM:SCP:REP 232->334|1l3wA3|3.8e-18|28.2|103/0|b.1.6.1|2/2|Cadherin-like| HM:SCP:REP 407->637|2erfA1|6.2e-29|28.4|194/0|b.29.1.4|1/1|Concanavalin A-like lectins/glucanases| OP:NHOMO 518 OP:NHOMOORG 66 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------2-------------------------------------------------------------------------------------------------------A78HC8C4444635DD686NzD2FBK26438566445553834E6F78C25257643863D2471------------------------ ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 530 STR:RPRED 50.2 SQ:SECSTR #####################################################################################################ccccccccccccccEEEEEEcccccTTccccccccccccccccTcGTccEEEEETcccEEEEEEEcTTTETcEEEcTTTccEEEEcccEEccccEcEEEcEEEEETcccccccccHHHcccEEEEEEEEEcccccccccccEEEEcGGGTTEEccEEEccccccEEEEETcEEETTEEEEEEEEEcccccEEEEEEcccEEcTTcEEEEEEEEEcTTccccccEEEEEEEcTTccEEEccEEEcTTTTTEEEEEEEcccccccEEEEEEETTTccccccTTcccEEEEEEEEEEccccccEE#####EEEcccEcEEEEcTTcEEcEEEcccccEEEEEEEEEEEEEEccGGGcccccEEEEEEEEEcccccccccEEEEEEEEcTTcccEEEEEEETTEEEEEEEccTccEEEcccEEEEcccccccccccEEEEEEEETTEEEEEETTcccEEEcccccccccccccEEEEEEccGGGTccEcccEEEccTcE##GGGccccccccccEEEEEEEEccGGGEEEEEcccccccGc################################################################################################################################################################################################################################################################################################################################################################################################################################## DISOP:02AL 5-44,83-87,769-779,913-920,967-970,994-1047| PSIPRED cccccccccccccccccccHHccccccccccccEEccccccccccccccccEEcccEEEEEEccccccccccEEEEEEccccccccccEEEEEEEEccEEEEEEEEcccccEEccEEEEEEEcccccccEEEEEEEEccccccccEEEEEEEEcccccEEEEEEccccccccEEEEcccccEEEEEEEcccccccccEEEEEEEEEEcccccccccccccEEEEEEEEEEEEcccccEEEccEEEEEEEccccccEEEEEEEEcccccccccEEEEEEEEcccccEEEcccEEEEEEcccccccccEEEEEEEEEEccccccEEEEEEEEEEEcccccEEccccEEEEEcccccccEEEEEEEEEEccccccccEEEEEEEccccccccccccEEEEEEEEEEEEEEEEEEEEcccccccEEEEEEEEEcccccccEEEEccEEEEEEccccccccccccEEEEEEEEccccccEEEEEEEEEcccccccEEEEEEEcccEEEEEEEccccccccccHHHHcccccHHccccccEEEEEEEccEEEEEEccEEcccccEEccccccccccccEEEEEEEEcccccccccccccccccccccccEEEEEEEcccEEEEEEEccccccHHHHHHHHHHHHcccccccccccccEEEEEcHHHcEEEEEcccHHHHHHHHHHHHHHccccccccccEEEEEEEEEEcccccccEEcccEEEEEEEEcccccEEEEEccccEEEEHHHHccccccEEccccEEEEEEEEcccccccccccccccccHHHHHHHcccccEEEEEEcccccccEEEEEEcHHHHHHcccEEEEcccEEEEEEccHHHHHHHHHHHcEEEccccHHHHccEEEEEEEEEccEEEccEEEEEEEEEEccccccccEEEEccccccccccccccccccccccccccccccccccEEEEEccccEEEEEccccccccccEEEEcccccccccccccccccEEEEEEEcHHHHccccccccccccccccccccccHHcccccccccccccccccccccccccccHHHcccccccccc 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