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Homo sapiens (cDNA) (huge0)
Gene : KIAA1003
DDBJ      :             KIAA1003
Swiss-Prot:UBP20_HUMAN  RecName: Full=Ubiquitin carboxyl-terminal hydrolase 20;         EC=3.1.2.15;AltName: Full=Ubiquitin thioesterase 20;AltName: Full=Ubiquitin-specific-processing protease 20;AltName: Full=Deubiquitinating enzyme 20;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  197/199 : Viruses  1/175   --->[See Alignment]
d.3.1d.324.1g.44.1
:917 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   9->100 2uzgA PDBj 6e-39 71.7 %
:BLT:PDB   148->237,438->685 2gfoA PDBj 2e-28 37.1 %
:BLT:PDB   821->883 1w6vA PDBj 4e-04 39.3 %
:RPS:PDB   8->118 3c5kA PDBj 2e-04 24.5 %
:RPS:PDB   150->251,536->687 2aynA PDBj 2e-25 28.3 %
:RPS:SCOP  9->101 2uzgA1  g.44.1.5 * 9e-16 71.0 %
:RPS:SCOP  144->252,443->687 2gfoA1  d.3.1.9 * 4e-35 37.0 %
:RPS:SCOP  713->783 1w6vA1  d.324.1.1 * 1e-09 21.1 %
:RPS:SCOP  789->897 1w6vA1  d.324.1.1 * 5e-23 31.1 %
:HMM:SCOP  134->687 2gfoA1 d.3.1.9 * 3.8e-94 39.2 %
:HMM:SCOP  684->779 1w6vA1 d.324.1.1 * 1.5e-18 29.2 %
:HMM:SCOP  780->893 1w6vA1 d.324.1.1 * 4.1e-24 34.0 %
:RPS:PFM   34->94 PF02148 * zf-UBP 2e-11 50.0 %
:RPS:PFM   150->288 PF00443 * UCH 3e-21 36.4 %
:RPS:PFM   432->685 PF00443 * UCH 1e-27 41.5 %
:RPS:PFM   821->896 PF06337 * DUSP 2e-11 49.3 %
:HMM:PFM   147->685 PF00443 * UCH 5.5e-71 43.7 252/271  
:HMM:PFM   655->780 PF06337 * DUSP 1.1e-08 26.6 79/99  
:HMM:PFM   820->891 PF06337 * DUSP 7.9e-18 43.1 72/99  
:HMM:PFM   34->95 PF02148 * zf-UBP 3.7e-18 40.0 60/64  
:BLT:SWISS 5->917 UBP20_HUMAN 0.0 99.8 %
:PROS 150->165|PS00972|UCH_2_1
:PROS 630->647|PS00973|UCH_2_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA1003 GT:ORG huge0 GT:GENE KIAA1003 GT:PRODUCT KIAA1003 GT:DATABASE huge2038 LENGTH 917 SQ:AASEQ AQARMGDSRDLCPHLDSIGEVTKEDLLLKSKGTCQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHAQAKKHNLTVNLTTFRLWCYACEKEVFLEQRLAAPLLGSSSKFSEQDSPPPSHPLKAVPIAVADEGESESEDDDLKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLVRTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPVVATVALTEARDSDSSDTDEKREGDRSPSEDEFLSCDSSSDRGEGDGQGRGGGSSQAETELLIPDEAGRVISEKERMKDRKFSWGQQRTNSEQVDEDADVDTAMAALDQPAEAQPPSPRSSSPCRTPEPDNDAHLRSSSRPCSPVHHHEGHAKLSSSPPRASPVRMAPSYVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQITTYDLLSVICHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQNAEGYVLFYRKSSEEAMRERQQVVSLAAMREPSLLRFYVSREWLNKFNTFAEPGPITNQTFLCSHGGIPPHKYHYIDDLVVILPQNVWEHLYNRFGGGPAVNHLYVCSICQVEIEALAKRRRIEIDTFIKLNKAFQAEESPGVIYCISMQWFREWEAFVKGKDNEPPGPIDNSRIAQVKGSGHVQLKQGADYGQISEETWTYLNSLYGGGPEIAIRQSVAQPLGPENLHGEQKIEAETRAV SW:ID UBP20_HUMAN SW:DE RecName: Full=Ubiquitin carboxyl-terminal hydrolase 20; EC=3.1.2.15;AltName: Full=Ubiquitin thioesterase 20;AltName: Full=Ubiquitin-specific-processing protease 20;AltName: Full=Deubiquitinating enzyme 20; SW:GN Name=USP20; Synonyms=KIAA1003, LSFR3A; SW:KW Complete proteome; Hydrolase; Metal-binding; Phosphoprotein;Polymorphism; Protease; Repeat; Thiol protease;Ubl conjugation pathway; Zinc; Zinc-finger. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 5->917|UBP20_HUMAN|0.0|99.8|913/914| GO:SWS:NREP 4 GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0008233|"GO:peptidase activity"|Protease| GO:SWS GO:0008234|"GO:cysteine-type peptidase activity"|Thiol protease| PROS 150->165|PS00972|UCH_2_1|PDOC00750| PROS 630->647|PS00973|UCH_2_2|PDOC00750| SEG 132->142|degeseseddd| SEG 291->310|dsssdrgegdgqgrgggssq| SEG 363->383|qpaeaqppsprssspcrtpep| BL:PDB:NREP 3 BL:PDB:REP 9->100|2uzgA|6e-39|71.7|92/95| BL:PDB:REP 148->237,438->685|2gfoA|2e-28|37.1|281/335| BL:PDB:REP 821->883|1w6vA|4e-04|39.3|61/120| RP:PDB:NREP 2 RP:PDB:REP 8->118|3c5kA|2e-04|24.5|106/108| RP:PDB:REP 150->251,536->687|2aynA|2e-25|28.3|243/337| RP:PFM:NREP 4 RP:PFM:REP 34->94|PF02148|2e-11|50.0|58/63|zf-UBP| RP:PFM:REP 150->288|PF00443|3e-21|36.4|131/337|UCH| RP:PFM:REP 432->685|PF00443|1e-27|41.5|205/337|UCH| RP:PFM:REP 821->896|PF06337|2e-11|49.3|75/102|DUSP| HM:PFM:NREP 4 HM:PFM:REP 147->685|PF00443|5.5e-71|43.7|252/271|UCH| HM:PFM:REP 655->780|PF06337|1.1e-08|26.6|79/99|DUSP| HM:PFM:REP 820->891|PF06337|7.9e-18|43.1|72/99|DUSP| HM:PFM:REP 34->95|PF02148|3.7e-18|40.0|60/64|zf-UBP| GO:PFM:NREP 5 GO:PFM GO:0008270|"GO:zinc ion binding"|PF02148|IPR001607| GO:PFM GO:0004221|"GO:ubiquitin thiolesterase activity"|PF00443|IPR001394| GO:PFM GO:0006511|"GO:ubiquitin-dependent protein catabolic process"|PF00443|IPR001394| GO:PFM GO:0004221|"GO:ubiquitin thiolesterase activity"|PF00443|IPR001394| GO:PFM GO:0006511|"GO:ubiquitin-dependent protein catabolic process"|PF00443|IPR001394| RP:SCP:NREP 4 RP:SCP:REP 9->101|2uzgA1|9e-16|71.0|93/95|g.44.1.5| RP:SCP:REP 144->252,443->687|2gfoA1|4e-35|37.0|300/339|d.3.1.9| RP:SCP:REP 713->783|1w6vA1|1e-09|21.1|70/120|d.324.1.1| RP:SCP:REP 789->897|1w6vA1|5e-23|31.1|103/120|d.324.1.1| HM:SCP:REP 134->687|2gfoA1|3.8e-94|39.2|342/0|d.3.1.9|1/1|Cysteine proteinases| HM:SCP:REP 684->779|1w6vA1|1.5e-18|29.2|96/0|d.324.1.1|1/2|DUSP-like| HM:SCP:REP 780->893|1w6vA1|4.1e-24|34.0|103/0|d.324.1.1|2/2|DUSP-like| OP:NHOMO 3208 OP:NHOMOORG 198 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1133ACF-A34189A4555466666556656665667766466666435555554553454555456436865657848765665475-79755766566566A991C89edjchXmIMOIOcL*rFqL***Ayd*MMJImHXkTITOLLdFIzIdYVVJVnGKKKAREBdBAJG4474e65659HIEW6NHA6896A8 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1---- STR:NPRED 515 STR:RPRED 56.2 SQ:SECSTR #######cccccTTGGGcccccTTccHHcTTcccTTTccccccccEEEETTTccEEEcTTTTcHHHHHHHHHcccEEEETTTccEEETTTTEEcccGGGHHHHHHHHHHHHcccccccc########################HHccccEEccccccHHHHHHHHHHHTcHHHHHHHHTccccccccHHHHHHHHHHHHHHHHHHHccEccEccHHHHHHHHHHcGGGGccccccHHHHHHHHHHHHHTTccc###cccccccccccTTccHHHH##################################################################################################################################################################HHHHHHcccHHHHHHcEEEEEEEEETTTccEEEEEEEEccEEEcccccc############ccccccEE############################cccccccHHHHHHHTTEEEEEEEccccEETTTTEEccEEEEEEEEEccccEEEEEEcccccccccccccccccccccEEEcGGGccHHHTccccEEEEEEEEEEEccTTccEEEEEEEEETTTEEEEEcTTccccccHHHHGGGGcEEEEEEcccT##################################################################################################################################EEEEHHHHHHHHHHHTTccTTcccccccTTT##cccccTTccccTTTEEEEcHHHHHHHHHHc################################## DISOP:02AL 1-11,252-275,288-444,687-715,896-909,917-918| PSIPRED ccccccccHHHcHHHHccccccHHHHccccccccEEccccccccEEEEEcccccccccccHHHHHHHHHHHccccEEEEEccccEEEcccccccccccccccccccccccccccccccccccccEEcccccccccccccccccccccccccccccHHHHHHHHHHHHHccHHHHHHHHHcccccccccccHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHccccccccccccccccccHHHcccccccccEEEEcccccccHHccccccccccccccccHHcccccccccccccccHHcccccccccccccccccccccccccccccccccccccccccccccccccccccHHHHHHccccccccHHccccccHHccccccccccccccHHHHHHHHHccHHHHcccccccccccEEEEEEEEEEEEEcccccEEEEEEccccccccccccccccccccccccccccccccccccccccccccccHHHcccccccccccccccccccHHHHHHHHcccEEEcccccEEccccccccEEEEEEEEEEcccEEEEEEEEEEEccccEEEcccEEEEEEEccEEcccHHcccccccccEEEEEEEEccccccccEEEEEEEEccccEEEEEEccEEEEccHHHHHcccccEEEEEEccHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHcccccccEEEcccEEEEcccccccHHHHHHHHHHcccHHHHHHHHHHHccccccccHHHccHHHHHcccHHHHHHHHHHHHHHHHHHHHHccccccEEEEEEHHHHHHHHHHHccccccccccccccccccccccccEEEEEcccEEEccHHHHHHHHHHccccccEEEEccccccccHHHHHHHHHHHHHcccc //