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Homo sapiens (cDNA) (huge0)
Gene : KIAA1050
DDBJ      :             KIAA1050
Swiss-Prot:MYT1_HUMAN   RecName: Full=Myelin transcription factor 1;         Short=MyT1;         Short=MyTI;AltName: Full=Proteolipid protein-binding protein;AltName: Full=PLPB1;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  64/199 : Viruses  0/175   --->[See Alignment]
a.47.2g.73.1
:829 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   146->193 1pxeA PDBj 6e-26 95.8 %
:BLT:PDB   185->221 2jydA PDBj 4e-10 62.2 %
:BLT:PDB   506->538 2jydA PDBj 3e-14 90.9 %
:BLT:PDB   543->586 2jydA PDBj 5e-22 95.5 %
:BLT:PDB   596->679 2cs8A PDBj 8e-33 73.5 %
:RPS:PDB   140->221 2cs8A PDBj 1e-04 42.9 %
:RPS:PDB   600->691 2cs8A PDBj 8e-05 68.5 %
:RPS:SCOP  146->193 1pxeA  g.73.1.1 * 7e-16 95.8 %
:RPS:SCOP  504->551 1pxeA  g.73.1.1 * 5e-14 54.2 %
:RPS:SCOP  551->592 1pxeA  g.73.1.1 * 6e-12 52.4 %
:RPS:SCOP  597->634 1pxeA  g.73.1.1 * 7e-10 52.6 %
:RPS:SCOP  650->696 1pxeA  g.73.1.1 * 7e-13 44.7 %
:RPS:SCOP  703->740 1dn1B  a.47.2.1 * 5e-04 29.7 %
:HMM:SCOP  146->193 1pxeA_ g.73.1.1 * 2.4e-14 60.4 %
:HMM:SCOP  194->237 1pxeA_ g.73.1.1 * 1.4e-09 45.5 %
:HMM:SCOP  504->547 1pxeA_ g.73.1.1 * 4e-13 65.9 %
:HMM:SCOP  548->595 1pxeA_ g.73.1.1 * 6.9e-14 58.3 %
:HMM:SCOP  597->644 1pxeA_ g.73.1.1 * 3.5e-12 56.2 %
:HMM:SCOP  650->697 1pxeA_ g.73.1.1 * 2e-12 54.2 %
:RPS:PFM   148->175 PF01530 * zf-C2HC 1e-09 82.1 %
:RPS:PFM   192->221 PF01530 * zf-C2HC 3e-08 70.0 %
:RPS:PFM   268->496 PF08474 * MYT1 1e-52 67.6 %
:RPS:PFM   506->535 PF01530 * zf-C2HC 6e-11 86.7 %
:RPS:PFM   550->579 PF01530 * zf-C2HC 6e-11 86.7 %
:RPS:PFM   599->628 PF01530 * zf-C2HC 7e-09 73.3 %
:RPS:PFM   654->681 PF01530 * zf-C2HC 1e-08 75.0 %
:RPS:PFM   701->735 PF08317 * Spc7 9e-04 42.9 %
:HMM:PFM   268->323 PF08474 * MYT1 1.9e-31 85.7 56/257  
:HMM:PFM   324->476 PF08474 * MYT1 9.4e-75 68.0 147/257  
:HMM:PFM   148->176 PF01530 * zf-C2HC 2.9e-16 72.4 29/31  
:HMM:PFM   192->221 PF01530 * zf-C2HC 1.8e-17 70.0 30/31  
:HMM:PFM   507->535 PF01530 * zf-C2HC 1.1e-18 79.3 29/31  
:HMM:PFM   550->579 PF01530 * zf-C2HC 5.6e-19 80.0 30/31  
:HMM:PFM   599->628 PF01530 * zf-C2HC 1.2e-17 70.0 30/31  
:HMM:PFM   653->681 PF01530 * zf-C2HC 9.6e-16 75.9 29/31  
:HMM:PFM   693->760 PF01496 * V_ATPase_I 3.9e-05 23.8 63/759  
:BLT:SWISS 15->829 MYT1_HUMAN 0.0 100.0 %
:REPEAT 6|143->180|187->221|501->535|545->581|589->628|642->681
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA1050 GT:ORG huge0 GT:GENE KIAA1050 GT:PRODUCT KIAA1050 GT:DATABASE huge2038 LENGTH 829 SQ:AASEQ EEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPLDTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV SW:ID MYT1_HUMAN SW:DE RecName: Full=Myelin transcription factor 1; Short=MyT1; Short=MyTI;AltName: Full=Proteolipid protein-binding protein;AltName: Full=PLPB1; SW:GN Name=MYT1; Synonyms=KIAA0835, KIAA1050, MTF1, MYTI, PLPB1; SW:KW Complete proteome; Developmental protein; Differentiation;DNA-binding; Metal-binding; Neurogenesis; Nucleus; Repeat;Transcription; Transcription regulation; Zinc; Zinc-finger. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 15->829|MYT1_HUMAN|0.0|100.0|815/1121| GO:SWS:NREP 8 GO:SWS GO:0007275|"GO:multicellular organismal development"|Developmental protein| GO:SWS GO:0030154|"GO:cell differentiation"|Differentiation| GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0007399|"GO:nervous system development"|Neurogenesis| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation| NREPEAT 1 REPEAT 6|143->180|187->221|501->535|545->581|589->628|642->681| SEG 1->14|eeeeeeeeeeeeee| SEG 393->400|sssscsss| SEG 413->431|sstsapsssmtspqssqas| SEG 450->468|eeepeesepaahsfassea| SEG 744->762|eknlknieeenklieeqne| BL:PDB:NREP 5 BL:PDB:REP 146->193|1pxeA|6e-26|95.8|48/48| BL:PDB:REP 185->221|2jydA|4e-10|62.2|37/46| BL:PDB:REP 506->538|2jydA|3e-14|90.9|33/46| BL:PDB:REP 543->586|2jydA|5e-22|95.5|44/46| BL:PDB:REP 596->679|2cs8A|8e-33|73.5|83/108| RP:PDB:NREP 2 RP:PDB:REP 140->221|2cs8A|1e-04|42.9|82/108| RP:PDB:REP 600->691|2cs8A|8e-05|68.5|92/108| RP:PFM:NREP 8 RP:PFM:REP 148->175|PF01530|1e-09|82.1|28/31|zf-C2HC| RP:PFM:REP 192->221|PF01530|3e-08|70.0|30/31|zf-C2HC| RP:PFM:REP 268->496|PF08474|1e-52|67.6|213/246|MYT1| RP:PFM:REP 506->535|PF01530|6e-11|86.7|30/31|zf-C2HC| RP:PFM:REP 550->579|PF01530|6e-11|86.7|30/31|zf-C2HC| RP:PFM:REP 599->628|PF01530|7e-09|73.3|30/31|zf-C2HC| RP:PFM:REP 654->681|PF01530|1e-08|75.0|28/31|zf-C2HC| RP:PFM:REP 701->735|PF08317|9e-04|42.9|35/325|Spc7| HM:PFM:NREP 9 HM:PFM:REP 268->323|PF08474|1.9e-31|85.7|56/257|MYT1| HM:PFM:REP 324->476|PF08474|9.4e-75|68.0|147/257|MYT1| HM:PFM:REP 148->176|PF01530|2.9e-16|72.4|29/31|zf-C2HC| HM:PFM:REP 192->221|PF01530|1.8e-17|70.0|30/31|zf-C2HC| HM:PFM:REP 507->535|PF01530|1.1e-18|79.3|29/31|zf-C2HC| HM:PFM:REP 550->579|PF01530|5.6e-19|80.0|30/31|zf-C2HC| HM:PFM:REP 599->628|PF01530|1.2e-17|70.0|30/31|zf-C2HC| HM:PFM:REP 653->681|PF01530|9.6e-16|75.9|29/31|zf-C2HC| HM:PFM:REP 693->760|PF01496|3.9e-05|23.8|63/759|V_ATPase_I| GO:PFM:NREP 24 GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| GO:PFM GO:0003700|"GO:transcription factor activity"|PF01530|IPR002515| GO:PFM GO:0005634|"GO:nucleus"|PF01530|IPR002515| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01530|IPR002515| GO:PFM GO:0008270|"GO:zinc ion binding"|PF01530|IPR002515| RP:SCP:NREP 6 RP:SCP:REP 146->193|1pxeA|7e-16|95.8|48/48|g.73.1.1| RP:SCP:REP 504->551|1pxeA|5e-14|54.2|48/48|g.73.1.1| RP:SCP:REP 551->592|1pxeA|6e-12|52.4|42/48|g.73.1.1| RP:SCP:REP 597->634|1pxeA|7e-10|52.6|38/48|g.73.1.1| RP:SCP:REP 650->696|1pxeA|7e-13|44.7|47/48|g.73.1.1| RP:SCP:REP 703->740|1dn1B|5e-04|29.7|37/222|a.47.2.1| HM:SCP:REP 146->193|1pxeA_|2.4e-14|60.4|48/48|g.73.1.1|1/6|CCHHC domain| HM:SCP:REP 194->237|1pxeA_|1.4e-09|45.5|44/48|g.73.1.1|2/6|CCHHC domain| HM:SCP:REP 504->547|1pxeA_|4e-13|65.9|44/48|g.73.1.1|3/6|CCHHC domain| HM:SCP:REP 548->595|1pxeA_|6.9e-14|58.3|48/48|g.73.1.1|4/6|CCHHC domain| HM:SCP:REP 597->644|1pxeA_|3.5e-12|56.2|48/48|g.73.1.1|5/6|CCHHC domain| HM:SCP:REP 650->697|1pxeA_|2e-12|54.2|48/48|g.73.1.1|6/6|CCHHC domain| OP:NHOMO 291 OP:NHOMOORG 64 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------566774933333449C363GV5573B44445444514442443534644221231111222111------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 260 STR:RPRED 31.4 SQ:SECSTR ###########################################################################################################################################cccccccccccccTTcccccccccccccccccTTcHHHHHHHcccccccccccccccccccccccTTccccccccTTTcHHHH###########################################################################################################################################################################################################################################################################################cccccTTcccccccccccccccccTTcHHHHHHHccTcccTTcTTccccccccccccccccccccccTTTcTTTTcccccc#########cccTccccTTcccccccccccccccccTTcHHHHHHHcccTTcccccccccccccccccccccccccccTTccccccccTTTcHHHHHHccccccc########################################################################################################################################## DISOP:02AL 1-17,27-74,97-150,198-215,221-254,307-323,352-366,380-490,520-548,578-599,631-655,658-659,680-714| PSIPRED cccccHHHHHHHHHccccccccccccccccccccccccccccccccccccEEEccccccccccHHHHHccccccHHHHHHHccccHHHHHHHHHHHHccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHccccHHHHccccccccccccccccccccccccccccccccccHHHHHHHHHHHHccccccccccccccccccccccccccccccccccccccccccccccHHHHHHHHHHHcccccccccccHHHHHHcccccccccccccccccccccHHHHHHHHHHHHHHHHcccHHHHHHHHHHcccccccccccccEEEccccccHHHcccccccccccccccccccccccccccccccccccccccHHccHHHHHHHccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccHHHcccccccccccccccccccccccccccccccccccccccccccccccccccHHHccccccccHHHHcccccccccccccHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccccccHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHcccc //