[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Homo sapiens (cDNA) (huge0)
Gene : KIAA1198
DDBJ      :             KIAA1198
Swiss-Prot:ZN490_HUMAN  RecName: Full=Zinc finger protein 490;

Homologs  Archaea  0/68 : Bacteria  0/915 : Eukaryota  186/199 : Viruses  0/175   --->[See Alignment]
a.138.1a.212.1g.37.1
:553 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   78->137 1v65A PDBj 3e-11 41.7 %
:BLT:PDB   150->240 1meyF PDBj 4e-17 43.5 %
:BLT:PDB   211->352 2i13A PDBj 4e-49 54.9 %
:BLT:PDB   327->381 1x6eA PDBj 5e-15 54.5 %
:BLT:PDB   381->413 2eowA PDBj 6e-08 54.5 %
:BLT:PDB   395->548 2i13A PDBj 2e-49 51.7 %
:RPS:PDB   166->228 2djrA PDBj 5e-05 12.9 %
:RPS:PDB   201->535 1ej6C PDBj 3e-53 11.4 %
:RPS:PDB   521->553 1bhiA PDBj 1e-05 28.6 %
:RPS:SCOP  80->528 1fs7A  a.138.1.3 * 2e-35 9.5 %
:RPS:SCOP  503->553 1yuiA  g.37.1.1 * 3e-09 19.6 %
:HMM:SCOP  74->137 1v65A_ a.212.1.1 * 2.2e-16 37.5 %
:HMM:SCOP  162->206 1ncsA_ g.37.1.1 * 8.9e-09 40.0 %
:HMM:SCOP  206->243 2cotA2 g.37.1.1 * 3.2e-10 55.3 %
:HMM:SCOP  226->281 1x3cA1 g.37.1.1 * 2.8e-21 62.5 %
:HMM:SCOP  273->300 1bboA1 g.37.1.1 * 1.1e-07 50.0 %
:HMM:SCOP  298->359 1yujA_ g.37.1.1 * 3.9e-20 61.1 %
:HMM:SCOP  338->393 1x3cA1 g.37.1.1 * 8.7e-18 51.8 %
:HMM:SCOP  380->407 1bhiA_ g.37.1.1 * 6.9e-05 50.0 %
:HMM:SCOP  394->449 1x3cA1 g.37.1.1 * 2.4e-20 58.9 %
:HMM:SCOP  436->463 1bhiA_ g.37.1.1 * 4.2e-07 53.6 %
:HMM:SCOP  450->505 1x3cA1 g.37.1.1 * 2e-18 50.0 %
:HMM:SCOP  496->548 2cshA1 g.37.1.1 * 1.3e-17 58.5 %
:RPS:PFM   81->121 PF01352 * KRAB 4e-13 56.1 %
:HMM:PFM   182->202 PF00096 * zf-C2H2 1.4e-05 42.9 21/23  
:HMM:PFM   218->240 PF00096 * zf-C2H2 1.1e-06 43.5 23/23  
:HMM:PFM   246->268 PF00096 * zf-C2H2 1.8e-06 39.1 23/23  
:HMM:PFM   274->296 PF00096 * zf-C2H2 9.3e-07 43.5 23/23  
:HMM:PFM   302->324 PF00096 * zf-C2H2 0.00027 43.5 23/23  
:HMM:PFM   330->352 PF00096 * zf-C2H2 2.9e-05 43.5 23/23  
:HMM:PFM   358->380 PF00096 * zf-C2H2 5.6e-07 34.8 23/23  
:HMM:PFM   386->408 PF00096 * zf-C2H2 2.8e-05 39.1 23/23  
:HMM:PFM   414->436 PF00096 * zf-C2H2 1.6e-07 47.8 23/23  
:HMM:PFM   442->464 PF00096 * zf-C2H2 3.2e-05 39.1 23/23  
:HMM:PFM   470->492 PF00096 * zf-C2H2 3.9e-06 47.8 23/23  
:HMM:PFM   526->548 PF00096 * zf-C2H2 1.2e-06 47.8 23/23  
:HMM:PFM   82->121 PF01352 * KRAB 2.3e-21 62.5 40/41  
:BLT:SWISS 25->553 ZN490_HUMAN 0.0 100.0 %
:PROS 180->202|PS00028|ZINC_FINGER_C2H2_1
:PROS 220->240|PS00028|ZINC_FINGER_C2H2_1
:PROS 248->268|PS00028|ZINC_FINGER_C2H2_1
:PROS 276->296|PS00028|ZINC_FINGER_C2H2_1
:PROS 304->324|PS00028|ZINC_FINGER_C2H2_1
:PROS 332->352|PS00028|ZINC_FINGER_C2H2_1
:PROS 360->380|PS00028|ZINC_FINGER_C2H2_1
:PROS 388->408|PS00028|ZINC_FINGER_C2H2_1
:PROS 416->436|PS00028|ZINC_FINGER_C2H2_1
:PROS 444->464|PS00028|ZINC_FINGER_C2H2_1
:PROS 472->492|PS00028|ZINC_FINGER_C2H2_1
:PROS 498->520|PS00028|ZINC_FINGER_C2H2_1
:PROS 528->548|PS00028|ZINC_FINGER_C2H2_1
:REPEAT 14|163->189|191->227|229->255|257->283|285->311|313->339|341->367|369->395|397->423|425->451|453->479|481->507|509->535|537->553
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA1198 GT:ORG huge0 GT:GENE KIAA1198 GT:PRODUCT KIAA1198 GT:DATABASE huge2038 LENGTH 553 SQ:AASEQ SRNCSGSRVGHGSLPAVFLDAGTGMRRNSSLSFQMERPLEEQVQSKWSSSQGRTGTGGSDVLQMQNSEHHGQSIKTQTDSISLEDVAVNFTLEEWALLDPGQRNIYRDVMRATFKNLACIGEKWKDQDIEDEHKNQGRNLRSPMVEALCENKEDCPCGKSTSQIPDLNTNLETPTGLKPCDCSVCGEVFMHQVSLNRHMRSHTEQKPNECHEYGEKPHKCKECGKTFTRSSSIRTHERIHTGEKPYECKECGKAFAFLFSFRNHIRIHTGETPYECKECGKAFRYLTALRRHEKNHTGEKPYKCKQCGKAFIYYQPFLTHERTHTGEKPYECKQCGKAFSCPTYLRSHEKTHTGEKPFVCRECGRAFFSHSSLRKHVKTHTGVQPYTCKKCGEAFKSSSSCEVHERTHFGEKPYECKQCGKAFNSSSYLQLHERVHTGEKTYECKECGKAFLYSTHFRIHERTHTREKPYECKQCGRVFIYFSHLRRHERSHTGVKPCECKQCGKAFTCLNSLKVHKRIHTGERPFQCRQCGKAFSYSKSLHVHERTHSRQKP SW:ID ZN490_HUMAN SW:DE RecName: Full=Zinc finger protein 490; SW:GN Name=ZNF490; Synonyms=KIAA1198; SW:KW Complete proteome; DNA-binding; Metal-binding; Nucleus; Repeat;Transcription; Transcription regulation; Zinc; Zinc-finger. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 25->553|ZN490_HUMAN|0.0|100.0|529/529| GO:SWS:NREP 5 GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation| PROS 180->202|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 220->240|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 248->268|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 276->296|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 304->324|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 332->352|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 360->380|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 388->408|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 416->436|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 444->464|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 472->492|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 498->520|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| PROS 528->548|PS00028|ZINC_FINGER_C2H2_1|PDOC00028| NREPEAT 1 REPEAT 14|163->189|191->227|229->255|257->283|285->311|313->339|341->367|369->395|397->423|425->451|453->479|481->507|509->535|537->553| SEG 48->59|sssqgrtgtggs| BL:PDB:NREP 6 BL:PDB:REP 78->137|1v65A|3e-11|41.7|60/64| BL:PDB:REP 150->240|1meyF|4e-17|43.5|81/84| BL:PDB:REP 211->352|2i13A|4e-49|54.9|142/151| BL:PDB:REP 327->381|1x6eA|5e-15|54.5|55/72| BL:PDB:REP 381->413|2eowA|6e-08|54.5|33/46| BL:PDB:REP 395->548|2i13A|2e-49|51.7|151/151| RP:PDB:NREP 3 RP:PDB:REP 166->228|2djrA|5e-05|12.9|53/76| RP:PDB:REP 201->535|1ej6C|3e-53|11.4|315/1221| RP:PDB:REP 521->553|1bhiA|1e-05|28.6|33/38| RP:PFM:NREP 1 RP:PFM:REP 81->121|PF01352|4e-13|56.1|41/41|KRAB| HM:PFM:NREP 13 HM:PFM:REP 182->202|PF00096|1.4e-05|42.9|21/23|zf-C2H2| HM:PFM:REP 218->240|PF00096|1.1e-06|43.5|23/23|zf-C2H2| HM:PFM:REP 246->268|PF00096|1.8e-06|39.1|23/23|zf-C2H2| HM:PFM:REP 274->296|PF00096|9.3e-07|43.5|23/23|zf-C2H2| HM:PFM:REP 302->324|PF00096|0.00027|43.5|23/23|zf-C2H2| HM:PFM:REP 330->352|PF00096|2.9e-05|43.5|23/23|zf-C2H2| HM:PFM:REP 358->380|PF00096|5.6e-07|34.8|23/23|zf-C2H2| HM:PFM:REP 386->408|PF00096|2.8e-05|39.1|23/23|zf-C2H2| HM:PFM:REP 414->436|PF00096|1.6e-07|47.8|23/23|zf-C2H2| HM:PFM:REP 442->464|PF00096|3.2e-05|39.1|23/23|zf-C2H2| HM:PFM:REP 470->492|PF00096|3.9e-06|47.8|23/23|zf-C2H2| HM:PFM:REP 526->548|PF00096|1.2e-06|47.8|23/23|zf-C2H2| HM:PFM:REP 82->121|PF01352|2.3e-21|62.5|40/41|KRAB| GO:PFM:NREP 3 GO:PFM GO:0003676|"GO:nucleic acid binding"|PF01352|IPR001909| GO:PFM GO:0005622|"GO:intracellular"|PF01352|IPR001909| GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01352|IPR001909| RP:SCP:NREP 2 RP:SCP:REP 80->528|1fs7A|2e-35|9.5|411/471|a.138.1.3| RP:SCP:REP 503->553|1yuiA|3e-09|19.6|51/54|g.37.1.1| HM:SCP:REP 74->137|1v65A_|2.2e-16|37.5|64/64|a.212.1.1|1/1|KRAB domain (Kruppel-associated box)| HM:SCP:REP 162->206|1ncsA_|8.9e-09|40.0|45/47|g.37.1.1|1/13|C2H2 and C2HC zinc fingers| HM:SCP:REP 206->243|2cotA2|3.2e-10|55.3|38/0|g.37.1.1|2/13|C2H2 and C2HC zinc fingers| HM:SCP:REP 226->281|1x3cA1|2.8e-21|62.5|56/0|g.37.1.1|3/8|C2H2 and C2HC zinc fingers| HM:SCP:REP 273->300|1bboA1|1.1e-07|50.0|28/28|g.37.1.1|4/13|C2H2 and C2HC zinc fingers| HM:SCP:REP 298->359|1yujA_|3.9e-20|61.1|54/54|g.37.1.1|4/8|C2H2 and C2HC zinc fingers| HM:SCP:REP 338->393|1x3cA1|8.7e-18|51.8|56/0|g.37.1.1|5/8|C2H2 and C2HC zinc fingers| HM:SCP:REP 380->407|1bhiA_|6.9e-05|50.0|28/0|g.37.1.1|8/13|C2H2 and C2HC zinc fingers| HM:SCP:REP 394->449|1x3cA1|2.4e-20|58.9|56/0|g.37.1.1|6/8|C2H2 and C2HC zinc fingers| HM:SCP:REP 436->463|1bhiA_|4.2e-07|53.6|28/0|g.37.1.1|10/13|C2H2 and C2HC zinc fingers| HM:SCP:REP 450->505|1x3cA1|2e-18|50.0|56/0|g.37.1.1|7/8|C2H2 and C2HC zinc fingers| HM:SCP:REP 496->548|2cshA1|1.3e-17|58.5|53/0|g.37.1.1|7/7|C2H2 and C2HC zinc fingers| OP:NHOMO 33422 OP:NHOMOORG 186 OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111226-1---B8C76A4AB9A9B7AAA9A7A799978788767699ADA9BAA896B8AA67755427648475635548888833-4B767665556457SUZ1D91*************************************************************s**W2--5*-11--88B6D47--JIJI- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 476 STR:RPRED 86.1 SQ:SECSTR #############################################################################cccccccccTTcccHHHHHTccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHcccccccGGGccccccccTHHHHHHHHccccccccHHHHccccTTccccccccccccHHHHHHHHHHHHcccccccTTcccTTcccccccccHHHHHHHHHHHHHHHHHHHTTcccccccEEccccccccTTcccccTTccTTcccTTccHHHHHHHHHTTccccccccccTTTccccccHHHHHHHHGGGTccccccTcTEEEEEEEccccccEEEEETcccEEEEEccccccETccccTTcEEEcccccccccEEccccccEEEEEEEcccccccccEEEEHHTTEEEEccccccEEEEEcTTcccccccccccGGGGcccccccccccccccGHHHHHHHHHHHHTTcEEccccEEEcccGGGTTcEEEccHHHHHHHTTccccHHHHH DISOP:02AL 1-6,8-9,26-79,138-146,549-554| PSIPRED ccccccccccccccHHHHHHcccccccccccccccccccHHHccccccccccccccccccccccccccccccccccccccccEEEEEEEccHHHHHHHcHHHHHHHHHHHHHHHHHHHcccccccccccccHHcccccccEEEEEEEccccccccccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEcccccccccccccccccEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEcccccccEEcccccEEEEcccccEEEEEccccccEEEcccccEEcccccccEEEEEcccccccEEcccccEEcccccccEEEEEcccccccEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEccccccc //