Homo sapiens (cDNA) (huge0)
Gene : KIAA1198
DDBJ : KIAA1198
Swiss-Prot:ZN490_HUMAN RecName: Full=Zinc finger protein 490;
Homologs Archaea 0/68 : Bacteria 0/915 : Eukaryota 186/199 : Viruses 0/175 --->[See Alignment]
a.138.1
a.212.1
g.37.1
:553 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB 78->137 1v65A PDBj 3e-11 41.7 %
:BLT:PDB 150->240 1meyF PDBj 4e-17 43.5 %
:BLT:PDB 211->352 2i13A PDBj 4e-49 54.9 %
:BLT:PDB 327->381 1x6eA PDBj 5e-15 54.5 %
:BLT:PDB 381->413 2eowA PDBj 6e-08 54.5 %
:BLT:PDB 395->548 2i13A PDBj 2e-49 51.7 %
:RPS:PDB 166->228 2djrA PDBj 5e-05 12.9 %
:RPS:PDB 201->535 1ej6C PDBj 3e-53 11.4 %
:RPS:PDB 521->553 1bhiA PDBj 1e-05 28.6 %
:RPS:SCOP 80->528 1fs7A a.138.1.3 * 2e-35 9.5 %
:RPS:SCOP 503->553 1yuiA g.37.1.1 * 3e-09 19.6 %
:HMM:SCOP 74->137 1v65A_ a.212.1.1 * 2.2e-16 37.5 %
:HMM:SCOP 162->206 1ncsA_ g.37.1.1 * 8.9e-09 40.0 %
:HMM:SCOP 206->243 2cotA2 g.37.1.1 * 3.2e-10 55.3 %
:HMM:SCOP 226->281 1x3cA1 g.37.1.1 * 2.8e-21 62.5 %
:HMM:SCOP 273->300 1bboA1 g.37.1.1 * 1.1e-07 50.0 %
:HMM:SCOP 298->359 1yujA_ g.37.1.1 * 3.9e-20 61.1 %
:HMM:SCOP 338->393 1x3cA1 g.37.1.1 * 8.7e-18 51.8 %
:HMM:SCOP 380->407 1bhiA_ g.37.1.1 * 6.9e-05 50.0 %
:HMM:SCOP 394->449 1x3cA1 g.37.1.1 * 2.4e-20 58.9 %
:HMM:SCOP 436->463 1bhiA_ g.37.1.1 * 4.2e-07 53.6 %
:HMM:SCOP 450->505 1x3cA1 g.37.1.1 * 2e-18 50.0 %
:HMM:SCOP 496->548 2cshA1 g.37.1.1 * 1.3e-17 58.5 %
:RPS:PFM 81->121 PF01352 * KRAB 4e-13 56.1 %
:HMM:PFM 182->202 PF00096 * zf-C2H2 1.4e-05 42.9 21/23
:HMM:PFM 218->240 PF00096 * zf-C2H2 1.1e-06 43.5 23/23
:HMM:PFM 246->268 PF00096 * zf-C2H2 1.8e-06 39.1 23/23
:HMM:PFM 274->296 PF00096 * zf-C2H2 9.3e-07 43.5 23/23
:HMM:PFM 302->324 PF00096 * zf-C2H2 0.00027 43.5 23/23
:HMM:PFM 330->352 PF00096 * zf-C2H2 2.9e-05 43.5 23/23
:HMM:PFM 358->380 PF00096 * zf-C2H2 5.6e-07 34.8 23/23
:HMM:PFM 386->408 PF00096 * zf-C2H2 2.8e-05 39.1 23/23
:HMM:PFM 414->436 PF00096 * zf-C2H2 1.6e-07 47.8 23/23
:HMM:PFM 442->464 PF00096 * zf-C2H2 3.2e-05 39.1 23/23
:HMM:PFM 470->492 PF00096 * zf-C2H2 3.9e-06 47.8 23/23
:HMM:PFM 526->548 PF00096 * zf-C2H2 1.2e-06 47.8 23/23
:HMM:PFM 82->121 PF01352 * KRAB 2.3e-21 62.5 40/41
:BLT:SWISS 25->553 ZN490_HUMAN 0.0 100.0 %
:PROS 180->202|PS00028|ZINC_FINGER_C2H2_1
:PROS 220->240|PS00028|ZINC_FINGER_C2H2_1
:PROS 248->268|PS00028|ZINC_FINGER_C2H2_1
:PROS 276->296|PS00028|ZINC_FINGER_C2H2_1
:PROS 304->324|PS00028|ZINC_FINGER_C2H2_1
:PROS 332->352|PS00028|ZINC_FINGER_C2H2_1
:PROS 360->380|PS00028|ZINC_FINGER_C2H2_1
:PROS 388->408|PS00028|ZINC_FINGER_C2H2_1
:PROS 416->436|PS00028|ZINC_FINGER_C2H2_1
:PROS 444->464|PS00028|ZINC_FINGER_C2H2_1
:PROS 472->492|PS00028|ZINC_FINGER_C2H2_1
:PROS 498->520|PS00028|ZINC_FINGER_C2H2_1
:PROS 528->548|PS00028|ZINC_FINGER_C2H2_1
:REPEAT 14|163->189|191->227|229->255|257->283|285->311|313->339|341->367|369->395|397->423|425->451|453->479|481->507|509->535|537->553
:SEG
SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA1198
GT:ORG huge0
GT:GENE KIAA1198
GT:PRODUCT KIAA1198
GT:DATABASE huge2038
LENGTH 553
SQ:AASEQ SRNCSGSRVGHGSLPAVFLDAGTGMRRNSSLSFQMERPLEEQVQSKWSSSQGRTGTGGSDVLQMQNSEHHGQSIKTQTDSISLEDVAVNFTLEEWALLDPGQRNIYRDVMRATFKNLACIGEKWKDQDIEDEHKNQGRNLRSPMVEALCENKEDCPCGKSTSQIPDLNTNLETPTGLKPCDCSVCGEVFMHQVSLNRHMRSHTEQKPNECHEYGEKPHKCKECGKTFTRSSSIRTHERIHTGEKPYECKECGKAFAFLFSFRNHIRIHTGETPYECKECGKAFRYLTALRRHEKNHTGEKPYKCKQCGKAFIYYQPFLTHERTHTGEKPYECKQCGKAFSCPTYLRSHEKTHTGEKPFVCRECGRAFFSHSSLRKHVKTHTGVQPYTCKKCGEAFKSSSSCEVHERTHFGEKPYECKQCGKAFNSSSYLQLHERVHTGEKTYECKECGKAFLYSTHFRIHERTHTREKPYECKQCGRVFIYFSHLRRHERSHTGVKPCECKQCGKAFTCLNSLKVHKRIHTGERPFQCRQCGKAFSYSKSLHVHERTHSRQKP
SW:ID ZN490_HUMAN
SW:DE RecName: Full=Zinc finger protein 490;
SW:GN Name=ZNF490; Synonyms=KIAA1198;
SW:KW Complete proteome; DNA-binding; Metal-binding; Nucleus; Repeat;Transcription; Transcription regulation; Zinc; Zinc-finger.
SW:EXACT F
SW:FUNC +
BL:SWS:NREP 1
BL:SWS:REP 25->553|ZN490_HUMAN|0.0|100.0|529/529|
GO:SWS:NREP 5
GO:SWS GO:0003677|"GO:DNA binding"|DNA-binding|
GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding|
GO:SWS GO:0005634|"GO:nucleus"|Nucleus|
GO:SWS GO:0006350|"GO:transcription"|Transcription|
GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation|
PROS 180->202|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 220->240|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 248->268|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 276->296|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 304->324|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 332->352|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 360->380|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 388->408|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 416->436|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 444->464|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 472->492|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 498->520|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
PROS 528->548|PS00028|ZINC_FINGER_C2H2_1|PDOC00028|
NREPEAT 1
REPEAT 14|163->189|191->227|229->255|257->283|285->311|313->339|341->367|369->395|397->423|425->451|453->479|481->507|509->535|537->553|
SEG 48->59|sssqgrtgtggs|
BL:PDB:NREP 6
BL:PDB:REP 78->137|1v65A|3e-11|41.7|60/64|
BL:PDB:REP 150->240|1meyF|4e-17|43.5|81/84|
BL:PDB:REP 211->352|2i13A|4e-49|54.9|142/151|
BL:PDB:REP 327->381|1x6eA|5e-15|54.5|55/72|
BL:PDB:REP 381->413|2eowA|6e-08|54.5|33/46|
BL:PDB:REP 395->548|2i13A|2e-49|51.7|151/151|
RP:PDB:NREP 3
RP:PDB:REP 166->228|2djrA|5e-05|12.9|53/76|
RP:PDB:REP 201->535|1ej6C|3e-53|11.4|315/1221|
RP:PDB:REP 521->553|1bhiA|1e-05|28.6|33/38|
RP:PFM:NREP 1
RP:PFM:REP 81->121|PF01352|4e-13|56.1|41/41|KRAB|
HM:PFM:NREP 13
HM:PFM:REP 182->202|PF00096|1.4e-05|42.9|21/23|zf-C2H2|
HM:PFM:REP 218->240|PF00096|1.1e-06|43.5|23/23|zf-C2H2|
HM:PFM:REP 246->268|PF00096|1.8e-06|39.1|23/23|zf-C2H2|
HM:PFM:REP 274->296|PF00096|9.3e-07|43.5|23/23|zf-C2H2|
HM:PFM:REP 302->324|PF00096|0.00027|43.5|23/23|zf-C2H2|
HM:PFM:REP 330->352|PF00096|2.9e-05|43.5|23/23|zf-C2H2|
HM:PFM:REP 358->380|PF00096|5.6e-07|34.8|23/23|zf-C2H2|
HM:PFM:REP 386->408|PF00096|2.8e-05|39.1|23/23|zf-C2H2|
HM:PFM:REP 414->436|PF00096|1.6e-07|47.8|23/23|zf-C2H2|
HM:PFM:REP 442->464|PF00096|3.2e-05|39.1|23/23|zf-C2H2|
HM:PFM:REP 470->492|PF00096|3.9e-06|47.8|23/23|zf-C2H2|
HM:PFM:REP 526->548|PF00096|1.2e-06|47.8|23/23|zf-C2H2|
HM:PFM:REP 82->121|PF01352|2.3e-21|62.5|40/41|KRAB|
GO:PFM:NREP 3
GO:PFM GO:0003676|"GO:nucleic acid binding"|PF01352|IPR001909|
GO:PFM GO:0005622|"GO:intracellular"|PF01352|IPR001909|
GO:PFM GO:0006355|"GO:regulation of transcription, DNA-dependent"|PF01352|IPR001909|
RP:SCP:NREP 2
RP:SCP:REP 80->528|1fs7A|2e-35|9.5|411/471|a.138.1.3|
RP:SCP:REP 503->553|1yuiA|3e-09|19.6|51/54|g.37.1.1|
HM:SCP:REP 74->137|1v65A_|2.2e-16|37.5|64/64|a.212.1.1|1/1|KRAB domain (Kruppel-associated box)|
HM:SCP:REP 162->206|1ncsA_|8.9e-09|40.0|45/47|g.37.1.1|1/13|C2H2 and C2HC zinc fingers|
HM:SCP:REP 206->243|2cotA2|3.2e-10|55.3|38/0|g.37.1.1|2/13|C2H2 and C2HC zinc fingers|
HM:SCP:REP 226->281|1x3cA1|2.8e-21|62.5|56/0|g.37.1.1|3/8|C2H2 and C2HC zinc fingers|
HM:SCP:REP 273->300|1bboA1|1.1e-07|50.0|28/28|g.37.1.1|4/13|C2H2 and C2HC zinc fingers|
HM:SCP:REP 298->359|1yujA_|3.9e-20|61.1|54/54|g.37.1.1|4/8|C2H2 and C2HC zinc fingers|
HM:SCP:REP 338->393|1x3cA1|8.7e-18|51.8|56/0|g.37.1.1|5/8|C2H2 and C2HC zinc fingers|
HM:SCP:REP 380->407|1bhiA_|6.9e-05|50.0|28/0|g.37.1.1|8/13|C2H2 and C2HC zinc fingers|
HM:SCP:REP 394->449|1x3cA1|2.4e-20|58.9|56/0|g.37.1.1|6/8|C2H2 and C2HC zinc fingers|
HM:SCP:REP 436->463|1bhiA_|4.2e-07|53.6|28/0|g.37.1.1|10/13|C2H2 and C2HC zinc fingers|
HM:SCP:REP 450->505|1x3cA1|2e-18|50.0|56/0|g.37.1.1|7/8|C2H2 and C2HC zinc fingers|
HM:SCP:REP 496->548|2cshA1|1.3e-17|58.5|53/0|g.37.1.1|7/7|C2H2 and C2HC zinc fingers|
OP:NHOMO 33422
OP:NHOMOORG 186
OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1111226-1---B8C76A4AB9A9B7AAA9A7A799978788767699ADA9BAA896B8AA67755427648475635548888833-4B767665556457SUZ1D91*************************************************************s**W2--5*-11--88B6D47--JIJI- -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
STR:NPRED 476
STR:RPRED 86.1
SQ:SECSTR #############################################################################cccccccccTTcccHHHHHTccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHcccccccGGGccccccccTHHHHHHHHccccccccHHHHccccTTccccccccccccHHHHHHHHHHHHcccccccTTcccTTcccccccccHHHHHHHHHHHHHHHHHHHTTcccccccEEccccccccTTcccccTTccTTcccTTccHHHHHHHHHTTccccccccccTTTccccccHHHHHHHHGGGTccccccTcTEEEEEEEccccccEEEEETcccEEEEEccccccETccccTTcEEEcccccccccEEccccccEEEEEEEcccccccccEEEEHHTTEEEEccccccEEEEEcTTcccccccccccGGGGcccccccccccccccGHHHHHHHHHHHHTTcEEccccEEEcccGGGTTcEEEccHHHHHHHTTccccHHHHH
DISOP:02AL 1-6,8-9,26-79,138-146,549-554|
PSIPRED ccccccccccccccHHHHHHcccccccccccccccccccHHHccccccccccccccccccccccccccccccccccccccccEEEEEEEccHHHHHHHcHHHHHHHHHHHHHHHHHHHcccccccccccccHHcccccccEEEEEEEccccccccccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEcccccccccccccccccEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEcccccccEEcccccEEEEcccccEEEEEccccccEEEcccccEEcccccccEEEEEcccccccEEcccccEEcccccccEEEEEcccccccEEcccccEEcccccccEEEEEccccccEEEcccccEEcccccccEEEEEccccccEEEcccccEEEEcccccEEEEccccccc
//
[GTOP]
