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Homo sapiens (cDNA) (huge0)
Gene : KIAA1268
DDBJ      :             KIAA1268
Swiss-Prot:PAR14_HUMAN  RecName: Full=Poly [ADP-ribose] polymerase 14;         Short=PARP-14;         EC=2.4.2.30;AltName: Full=B aggressive lymphoma protein 2;

Homologs  Archaea  26/68 : Bacteria  252/915 : Eukaryota  102/199 : Viruses  0/175   --->[See Alignment]
c.50.1d.289.1
:1023 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   149->313 1spvA PDBj 8e-17 35.8 %
:BLT:PDB   356->531 1yd9C PDBj 1e-16 27.5 %
:BLT:PDB   562->714 1hjzA PDBj 5e-11 35.6 %
:BLT:PDB   859->944 1x4rA PDBj 4e-22 53.5 %
:BLT:PDB   956->1000 3goyD PDBj 2e-17 80.0 %
:RPS:PDB   143->321 2bfqA PDBj 3e-29 25.5 %
:RPS:PDB   355->532 2bfqA PDBj 1e-21 18.5 %
:RPS:PDB   562->729 2bfqA PDBj 3e-31 26.8 %
:RPS:PDB   800->944 2a90A PDBj 1e-16 14.3 %
:RPS:PDB   947->1023 3bljB PDBj 1e-12 33.8 %
:RPS:SCOP  147->318 1spvA  c.50.1.2 * 5e-35 32.1 %
:RPS:SCOP  361->532 1spvA  c.50.1.2 * 3e-25 25.4 %
:RPS:SCOP  562->729 1hjzA  c.50.1.2 * 2e-32 27.4 %
:RPS:SCOP  845->949 1ujrA  d.289.1.1 * 3e-19 19.6 %
:HMM:SCOP  121->323 1njrA_ c.50.1.2 * 9.7e-60 37.6 %
:HMM:SCOP  340->532 1zr5A1 c.50.1.2 * 7.4e-46 37.8 %
:HMM:SCOP  536->744 1njrA_ c.50.1.2 * 5.5e-51 30.3 %
:HMM:SCOP  835->944 1ujrA_ d.289.1.1 * 9.8e-22 32.3 %
:RPS:PFM   189->272 PF01661 * Macro 9e-12 40.5 %
:RPS:PFM   383->483 PF01661 * Macro 8e-15 36.6 %
:RPS:PFM   588->677 PF01661 * Macro 2e-05 27.9 %
:RPS:PFM   875->930 PF02825 * WWE 2e-04 30.4 %
:HMM:PFM   163->279 PF01661 * Macro 5.5e-34 40.2 117/118  
:HMM:PFM   387->490 PF01661 * Macro 1.8e-21 31.4 102/118  
:HMM:PFM   588->689 PF01661 * Macro 7.6e-13 27.5 102/118  
:HMM:PFM   879->929 PF02825 * WWE 8.1e-08 25.5 51/72  
:HMM:PFM   538->591 PF05132 * RNA_pol_Rpc4 0.00063 24.1 54/131  
:BLT:SWISS 1->1000 PAR14_HUMAN 0.0 99.1 %
:REPEAT 3|145->318|358->530|570->727
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA1268 GT:ORG huge0 GT:GENE KIAA1268 GT:PRODUCT KIAA1268 GT:DATABASE huge2038 LENGTH 1023 SQ:AASEQ YKLLFNFVEQNMKIERLVEVKPSLVIDYLKTEKKLFWPKIKKVNVQVSFNPENKQKGILLTGSKTEVLKAVDIVKQVWDSVCVKSVHTDKPGAKQFFQDKARFYQSEIKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFKATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQSVMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCPYTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGISRDVMQARDEIEAMIKRVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHYTVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKVSLLLECSFWMVEISSVMVLYKIHFHSLPITFF SW:ID PAR14_HUMAN SW:DE RecName: Full=Poly [ADP-ribose] polymerase 14; Short=PARP-14; EC=2.4.2.30;AltName: Full=B aggressive lymphoma protein 2; SW:GN Name=PARP14; Synonyms=BAL2, KIAA1268; SW:KW 3D-structure; Alternative splicing; Complete proteome; Cytoplasm;Glycosyltransferase; NAD; Nucleus; Repeat; Transcription;Transcription regulation; Transferase. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1000|PAR14_HUMAN|0.0|99.1|1000/1720| GO:SWS:NREP 6 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016757|"GO:transferase activity, transferring glycosyl groups"|Glycosyltransferase| GO:SWS GO:0005634|"GO:nucleus"|Nucleus| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0045449|"GO:regulation of transcription"|Transcription regulation| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| NREPEAT 1 REPEAT 3|145->318|358->530|570->727| SEG 174->188|gglaaalskaagpel| SEG 323->342|atlpdtaappglppaaagpg| BL:PDB:NREP 5 BL:PDB:REP 149->313|1spvA|8e-17|35.8|159/171| BL:PDB:REP 356->531|1yd9C|1e-16|27.5|171/187| BL:PDB:REP 562->714|1hjzA|5e-11|35.6|149/192| BL:PDB:REP 859->944|1x4rA|4e-22|53.5|86/99| BL:PDB:REP 956->1000|3goyD|2e-17|80.0|45/182| RP:PDB:NREP 5 RP:PDB:REP 143->321|2bfqA|3e-29|25.5|174/191| RP:PDB:REP 355->532|2bfqA|1e-21|18.5|171/191| RP:PDB:REP 562->729|2bfqA|3e-31|26.8|164/191| RP:PDB:REP 800->944|2a90A|1e-16|14.3|140/155| RP:PDB:REP 947->1023|3bljB|1e-12|33.8|77/198| RP:PFM:NREP 4 RP:PFM:REP 189->272|PF01661|9e-12|40.5|83/117|Macro| RP:PFM:REP 383->483|PF01661|8e-15|36.6|101/117|Macro| RP:PFM:REP 588->677|PF01661|2e-05|27.9|90/117|Macro| RP:PFM:REP 875->930|PF02825|2e-04|30.4|56/70|WWE| HM:PFM:NREP 5 HM:PFM:REP 163->279|PF01661|5.5e-34|40.2|117/118|Macro| HM:PFM:REP 387->490|PF01661|1.8e-21|31.4|102/118|Macro| HM:PFM:REP 588->689|PF01661|7.6e-13|27.5|102/118|Macro| HM:PFM:REP 879->929|PF02825|8.1e-08|25.5|51/72|WWE| HM:PFM:REP 538->591|PF05132|0.00063|24.1|54/131|RNA_pol_Rpc4| RP:SCP:NREP 4 RP:SCP:REP 147->318|1spvA|5e-35|32.1|168/172|c.50.1.2| RP:SCP:REP 361->532|1spvA|3e-25|25.4|167/172|c.50.1.2| RP:SCP:REP 562->729|1hjzA|2e-32|27.4|164/192|c.50.1.2| RP:SCP:REP 845->949|1ujrA|3e-19|19.6|97/110|d.289.1.1| HM:SCP:REP 121->323|1njrA_|9.7e-60|37.6|202/0|c.50.1.2|1/3|Macro domain-like| HM:SCP:REP 340->532|1zr5A1|7.4e-46|37.8|185/0|c.50.1.2|2/3|Macro domain-like| HM:SCP:REP 536->744|1njrA_|5.5e-51|30.3|208/0|c.50.1.2|3/3|Macro domain-like| HM:SCP:REP 835->944|1ujrA_|9.8e-22|32.3|96/0|d.289.1.1|1/1|WWE domain| OP:NHOMO 726 OP:NHOMOORG 380 OP:PATTERN ------11111111111111111----------------------1---1111----11---11---- -11---------------------1------1----111111--------11--------1-------11-------1---1-1-111---1-111---------11------------------11---------11111---1-1112--------------1------------------1-1--11-----------------------------------111111---11111-11-111----------1--111-1--11---1-------111----------------------------------111----1----1111111-1---111----11--122-1---11111111111-11-1------------111---11-----------------------11---------------1-----1--------------------11------------------------------------------------------11--------111-1--11----------1---11---1------1----12--11111-1-1-----11111111111111-11-----------------------11---------1---------------------1---11--------11---1-1111111111-1111111111111111111111-----1111111111-1111--1111111-----------------1-----------11-----1-------------------1--11-1---------------------------------1---1111111111------1-----11--------2---------------------------111111111111- ----1----------1-1211---1-2111111----------1-122--1111---11111-----------------------1----2--1-1------1-1--2-3R7974A23342354744B4Of81A6D45437544425442533B6633C8B8246-1------29--------112--22----1332- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 768 STR:RPRED 75.1 SQ:SECSTR ##################################################################################################################################ccccEEEEEEcTTcccEEEEEccHHHHHccEEEEEccTTcccccHHHHHHHHHTTTHHHHHHHHHHHHHccccTTcEEEEEcTTTcccEEEEEccccTTTTccGTcHHHHHHHGGHHHHHHGGGGccEEEEccTTcGGGcccHHHHHHHHHHHcccEEEEEEccHHHHHHHHHHHHHHHccHHHHHHHHHc###########################ccccccTTEEEEEEEccGGGccccEEEEEEcTTccccccHHHHHHHHHHHccHHHHHHHHHccccccTTccEEEEcGGGGGGEEEEEEccccTTcccHHHHHHHHHHHHHHHHHHHHTccEEEEccTTccTTcccHHHHHHHHHHHHHHcEEEEccccccEEEEEEcHHcHHHHHHHHHHHHHH#########################ccccEEEEEETTEEEEEEEccGGGccccEEEEEEcTTcccccHHHHHHHHHHHccHHHHHHHHHHHHcccccEEEcGGGTccEEEEEEcccHHHHHHHHHHHHHHHHTccEEEEccTTccTTcccHHHHHHHHHHHHHHcccEEccccccEEEEEEccHHHHHHHHHHHHHH######################################################################EEEETTEEEEccHHHHHHHHHHHHT#TccEEGGGTcTTcTTcEE##ETTTEEEcccccEEEEEcTTcHHHHTEEEEEEHHcccccccccEEEccHHHHHHHHHHHTTccEEEHHTccccEEEETTTTEEEETTTccEEEEEEEcccccccccHHHHHHTcEEEEEccTTcHHHHHHHHHHHHTccGGGTTEEEEEEEEHHHHHHHHHHHHHHEEEEEEEcGGGH DISOP:02AL 119-136,321-347,545-559,728-768,825-831| PSIPRED ccHHHHHHHcccEEEEEccccHHHHHHHHHHHHHHHHHHHHcccEEEEEEccccccEEEEcccHHHHHHHHHHHHHHHHHEEEEEEEEccHHHHHHHHHHHHHHHHHHHHHHcEEEEEEEccccccccccccccEEEEEEcccccEEEEEEcccccccccEEEEccccccccccHHHHHHHHHccHHHHHHHHHHHHHHcccccccEEEEccccccccEEEEEccccccccccHHHHHHHHHHHHHHHHHHHHccccEEEEccHHHHHccccHHHHHHHHHHHHHHHHHHccccccccEEEEEEccHHHHHHHHHHHHHHccccHHHcccccccccccccccccccccccEEEccccEEEEEEcccHHccccEEEEcccccccccccHHHHHHHHHccHHHHHHHHHHHHcccccccEEEEEccccccccEEEEEcccccccccccHHHHHHHHHHHHHHHHHHccccEEEEcccccccccccHHHHHHHHHHHHHHHHHHcccccEEEEEEEEEcccHHHHHHHHHHHHHHHcccccccccccccccccccccccccccccHHHHcccEEEEEEEcccccccccEEEEccccccccccHHHHHHHHHHcHHHHHHHHHHcccccccEEEEccccccccEEEEcccHHHHHHHHHHHHHHHHHccccEEEEcccccccccccHHHHHHHHHHHHHHHHHHcccccccEEEEEEccHHHHHHHHHHHHccccccccccccccccHHHccccccccccccccEEEEccccccEEEEEcccHHHHHHHHHHHHHHHHcccccEEEcccHHHcHHHHHHHHHHHHccccEEEEEEcccccEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcEEEEccccccccHHHHHHHHHHHHHcccccEEEEEccEEEEEEEccEEEEcccccEEEEEEcccccccccHHHcccccccEEEEEEccccHHHHHHHHHHHccccccEEEEEEEEcccHHHHHEccEEEEEEEEEEccccEEcc //