Homo sapiens (cDNA) (huge0)
Gene : KIAA1406
DDBJ : KIAA1406
Swiss-Prot:ANC2_HUMAN RecName: Full=Anaphase-promoting complex subunit 2; Short=APC2;AltName: Full=Cyclosome subunit 2;
Homologs Archaea 0/68 : Bacteria 0/915 : Eukaryota 181/199 : Viruses 0/175 --->[See Alignment]
a.4.5
e.40.1
:571 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB 261->445 2hyeC PDBj 7e-12 26.2 %
:BLT:PDB 506->566 1lddA PDBj 4e-05 36.1 %
:RPS:PDB 259->557 3dqvC PDBj 3e-39 21.5 %
:RPS:SCOP 255->460 2hyeC3 e.40.1.1 * 3e-52 25.5 %
:RPS:SCOP 495->566 1lddA a.4.5.34 * 2e-26 31.9 %
:HMM:SCOP 260->445 1ldjA3 e.40.1.1 * 2.2e-29 28.4 %
:HMM:SCOP 495->567 1lddA_ a.4.5.34 * 3.7e-23 49.3 %
:RPS:PFM 261->460 PF00888 * Cullin 8e-17 30.8 %
:RPS:PFM 506->566 PF08672 * APC2 3e-09 47.5 %
:HMM:PFM 71->100 PF00888 * Cullin 0.00086 26.7 30/589
:HMM:PFM 115->483 PF00888 * Cullin 2.4e-84 31.5 324/589
:HMM:PFM 506->566 PF08672 * APC2 1.8e-24 41.7 60/60
:BLT:SWISS 1->571 ANC2_HUMAN 0.0 100.0 %
:SEG
SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA1406
GT:ORG huge0
GT:GENE KIAA1406
GT:PRODUCT KIAA1406
GT:DATABASE huge2038
LENGTH 571
SQ:AASEQ LLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQDGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLDRIYNMLRMFVVTGPALAEIDLQELQGYLQKKVRDQQLVYSAGVYRLPKNCS
SW:ID ANC2_HUMAN
SW:DE RecName: Full=Anaphase-promoting complex subunit 2; Short=APC2;AltName: Full=Cyclosome subunit 2;
SW:GN Name=ANAPC2; Synonyms=APC2, KIAA1406;
SW:KW Alternative splicing; Cell cycle; Cell division; Complete proteome;Mitosis; Phosphoprotein; Ubl conjugation pathway.
SW:EXACT F
SW:FUNC +
BL:SWS:NREP 1
BL:SWS:REP 1->571|ANC2_HUMAN|0.0|100.0|571/822|
GO:SWS:NREP 3
GO:SWS GO:0007049|"GO:cell cycle"|Cell cycle|
GO:SWS GO:0051301|"GO:cell division"|Cell division|
GO:SWS GO:0007067|"GO:mitosis"|Mitosis|
SEG 190->201|gltgdsdgtgdl|
SEG 240->254|kssskrrssdiisll|
BL:PDB:NREP 2
BL:PDB:REP 261->445|2hyeC|7e-12|26.2|183/719|
BL:PDB:REP 506->566|1lddA|4e-05|36.1|61/74|
RP:PDB:NREP 1
RP:PDB:REP 259->557|3dqvC|3e-39|21.5|274/363|
RP:PFM:NREP 2
RP:PFM:REP 261->460|PF00888|8e-17|30.8|198/578|Cullin|
RP:PFM:REP 506->566|PF08672|3e-09|47.5|59/60|APC2|
HM:PFM:NREP 3
HM:PFM:REP 71->100|PF00888|0.00086|26.7|30/589|Cullin|
HM:PFM:REP 115->483|PF00888|2.4e-84|31.5|324/589|Cullin|
HM:PFM:REP 506->566|PF08672|1.8e-24|41.7|60/60|APC2|
GO:PFM:NREP 3
GO:PFM GO:0006511|"GO:ubiquitin-dependent protein catabolic process"|PF00888|IPR001373|
GO:PFM GO:0031461|"GO:cullin-RING ubiquitin ligase complex"|PF00888|IPR001373|
GO:PFM GO:0031625|"GO:ubiquitin protein ligase binding"|PF00888|IPR001373|
RP:SCP:NREP 2
RP:SCP:REP 255->460|2hyeC3|3e-52|25.5|204/273|e.40.1.1|
RP:SCP:REP 495->566|1lddA|2e-26|31.9|72/74|a.4.5.34|
HM:SCP:REP 260->445|1ldjA3|2.2e-29|28.4|183/0|e.40.1.1|1/1|Cullin homology domain|
HM:SCP:REP 495->567|1lddA_|3.7e-23|49.3|73/0|a.4.5.34|1/1|"Winged helix" DNA-binding domain|
OP:NHOMO 455
OP:NHOMOORG 181
OP:PATTERN -------------------------------------------------------------------- --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ----222-211-11211112331222222221222222222222222222222222121222121--1-1-1112222112-111123-24112332212211122-2442223324111-13255131Ac52426111-21211-222231-21222212111221121483212-32Y3232264671333424232 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
STR:NPRED 305
STR:RPRED 53.4
SQ:SECSTR ##################################################################################################################################################################################################################################################################ccTHHHHHHHHHHHHHHHHTTccccHHHHHHHHHHHHHTTcHHHHHHHHHHHHHHHHHHHHHHHHHHcccccGGGcccTcccccccccTTTccccccccccccHHHHHHHHHHHHHHHTTcTTccccccTGTcEEEEEccccccEEEEEEEHHHHHHHHTcTTcTTEEHHHHHHHHcccHHHHHHHHHHHcccccEEEccccccccccccccccEEEEEccccccTHHHHHHHHHHHHHHHHHH###HHHHHHHHHHccEEcHHHHHHHHHHHGGGccTTccHHHTTTccccHHHHHHHEccTTEEEE#####
DISOP:02AL 2-2,198-198,202-223,237-245,326-336,479-498,571-572|
PSIPRED cHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHccccHHHHHHHHHHHccccccccHHHHHHcccHHHHccccccccccccHHHHcccccccccccccHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHccccccccccEEEEEEccccccccccccEEccHHHHHHHHHHHHHHHHcccccEEEEEEccEEEEEEEEEccEEEEEEEcHHHHHHHHHHcccccEEHHHHHHHHcccHHHHHHHHHHHHcccEEEEccccEEEEEccccccccEEEEcccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHcccccccccccHHHHHHHHHHHHHcccEEEEccEEEEccccc
//
[GTOP]
