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Homo sapiens (cDNA) (huge0)
Gene : KIAA1801
DDBJ      :             KIAA1801
Swiss-Prot:LRIQ1_HUMAN  RecName: Full=Leucine-rich repeat and IQ domain-containing protein 1;

Homologs  Archaea  0/68 : Bacteria  1/915 : Eukaryota  56/199 : Viruses  0/175   --->[See Alignment]
c.10.2
:1227 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   102->185 2ap3A PDBj 9e-04 28.4 %
:BLT:PDB   702->787 1h6uA PDBj 3e-04 29.9 %
:BLT:PDB   855->1010 2omuA PDBj 4e-08 28.6 %
:RPS:PDB   697->914 1dceA PDBj 2e-12 17.3 %
:RPS:PDB   887->1033 1a9nA PDBj 5e-08 15.1 %
:RPS:SCOP  663->1039 1o6sA2  c.10.2.1 * 6e-26 22.3 %
:HMM:SCOP  14->792 1jl5A_ c.10.2.6 * 1.1e-15 21.2 %
:HMM:SCOP  590->1101 1o6vA2 c.10.2.1 * 5.1e-40 28.5 %
:RPS:PFM   103->174 PF02841 * GBP_C 1e-04 31.0 %
:HMM:PFM   710->730 PF00560 * LRR_1 0.00073 57.1 21/22  
:HMM:PFM   176->194 PF00612 * IQ 0.00014 42.1 19/21  
:BLT:SWISS 13->1227 LRIQ1_HUMAN 0.0 99.9 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links HUGE Abbreviations Back to title page
GT:ID KIAA1801 GT:ORG huge0 GT:GENE KIAA1801 GT:PRODUCT KIAA1801 GT:DATABASE huge2038 LENGTH 1227 SQ:AASEQ RTRFKDQQEKEEFMRSKTDCATPDFVPEPSPHDLPMDEHVLPDDADINFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLKEQFPLQELKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPKDNAWNSGIVIFNTTDTMINIEGKRNDQDYVLGRHAPCEGLSNYNAESSMVSKEVNSLKSEIRNISEKCHENAPEPDSMTCCVSESTLLYSIEERRLAWIKSFKPWLEIFKQNQQKKIVRRKRPVKCPANMTPALDKLEILRCGPWDTLQQVTTVTFQDLPGCVLSTLAECTNLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECENLENLCVVLLNKNQLTSLHGLDGCTNIQCLELSYNKITRIGYSFFLEEKLVDNTGFCHHLGTSTSYLSLAQVWIPTGLCWSWIPITSLTKNSDCNFLISHLYWNCGLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALRILNGNILNSNSESRTEEHNQLGSAGFLALCQSQIREFNLLIENYITGKGDVFTLDTAENLCHYFKKLMILSTEYRHAHERGDVTITKKDESEAQKNHLAPTNSDSTLQNGVFYSCAREGEPDSPDIPEKWMDSVSSHSPLSKSATCENMEGRHQEILVCQKREDSKASSIPTIRIPFKEVVMTNSLLRNHQNIEPSEKM SW:ID LRIQ1_HUMAN SW:DE RecName: Full=Leucine-rich repeat and IQ domain-containing protein 1; SW:GN Name=LRRIQ1; Synonyms=KIAA1801; SW:KW Alternative splicing; Coiled coil; Complete proteome;Leucine-rich repeat; Polymorphism; Repeat. SW:EXACT F SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 13->1227|LRIQ1_HUMAN|0.0|99.9|1215/1336| SEG 66->78|qekqkeledkekq| SEG 87->97|eekqfqeeeek| SEG 220->259|rqkeeenrkrleeeqrikeerkkqkeeerkrrekeyeekk| SEG 463->485|qkiikdnqqkkiqkvekeeiqeq| SEG 523->535|ekeiyskskeiee| SEG 747->760|ecenlenlcvvlln| SEG 916->933|lselpslenlvllrelhl| BL:PDB:NREP 3 BL:PDB:REP 102->185|2ap3A|9e-04|28.4|81/192| BL:PDB:REP 702->787|1h6uA|3e-04|29.9|86/308| BL:PDB:REP 855->1010|2omuA|4e-08|28.6|154/462| RP:PDB:NREP 2 RP:PDB:REP 697->914|1dceA|2e-12|17.3|196/566| RP:PDB:REP 887->1033|1a9nA|5e-08|15.1|146/162| RP:PFM:NREP 1 RP:PFM:REP 103->174|PF02841|1e-04|31.0|71/286|GBP_C| HM:PFM:NREP 2 HM:PFM:REP 710->730|PF00560|0.00073|57.1|21/22|LRR_1| HM:PFM:REP 176->194|PF00612|0.00014|42.1|19/21|IQ| GO:PFM:NREP 2 GO:PFM GO:0003924|"GO:GTPase activity"|PF02841|IPR003191| GO:PFM GO:0005525|"GO:GTP binding"|PF02841|IPR003191| RP:SCP:NREP 1 RP:SCP:REP 663->1039|1o6sA2|6e-26|22.3|363/381|c.10.2.1| HM:SCP:REP 14->792|1jl5A_|1.1e-15|21.2|151/0|c.10.2.6|1/2|L domain-like| HM:SCP:REP 590->1101|1o6vA2|5.1e-40|28.5|383/0|c.10.2.1|1/1|L domain-like| OP:NHOMO 83 OP:NHOMOORG 57 OP:PATTERN -------------------------------------------------------------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------1----------------------11-------------1-----------------------------------------------------------------2--111211111111112146212141-112-1211111111-31312111--13--------12--1-1------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 597 STR:RPRED 48.7 SQ:SECSTR #####################################################################################################HHHHHHHHTTc#cc###ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH##################################################################################################################################################################################################################################################################################################################################################################EEEEEETTEEEEEEEcccccTTcccccccccccccTTTTccHHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHHHccccccccccTTEEcccGGEEEEEcTTccEEEEEccEEEEEccccTTccEEEccccccccccccccTTTTcTTTTccEEEcccccEEEEEcccTTTTcccccccHHHHHHHHHHHHHHHHHHHcTTcHHHHHHHEEcTTccTTcTTcccccccccTHHHHHHHcTGGGHHHHHHHHHHHHHHcGGGHHHHHHHHHHHHHHHHHHHHHHTTccEEEcTTccccccccGGGGTTccEEEccccGGGGcTTccEEEcccccccccGGGTTcccccEEEcccccccccGGGGGcTTccEEEcTTccccEEcTTTTTTcTTccEccTTccccccccccTTcTTccEEEcccccccEEcTTTTcccccEEEcccccccEEcEcTTcccccccccEEEcTTccccTccccHHHHHHHHccccEEETTTTEEccHHHHHHHHHTTccHHHH########################################################################################################################################################################### DISOP:02AL 1-2,22-25,70-75,219-249,301-302,305-305,350-359,372-394,417-451,453-453,467-515,568-616,1177-1177,1179-1179,1220-1228| PSIPRED cccHHHHHHHHHHHHHcccccccccccccccccccccccccHHHcccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHccHHHHHHccHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHcccccccccccccccccHHHHccccccHHHHHHHHHHHHHHccccccccHHHHHHHHHHcccccccccccccccccccccccccccccHHHccccHHHHHHcccccHHHHHHHHHHHcccEEccccccEEEccccccccccccccccccHHHccccccccccccccccccccHHHHHHHHHcccccccccccccccccccccccccccHHHHccHHHHHHHHcccccccccccHHccccHHHccccccccccccccccccccccEEEEccccccccccHHHcccccEEEcccccccccccccccccccEEEccccccccccHHHcccccEEEcccccccccccccccccccEEEccccccccccHHHHcHHHHHHHccccccccccccccccccccccccccccccccccccccccccccccccccccHHHccccccEEEcccccccccccccccccccEEEcccccccccccccccccccEEEcccccccccccccccccccEEEcccccccccccHHHcccccccEEEcccccccccccccccccccEEEcccccccccccHHHHHcccccccEEEccccccccccccccHHHHHccccccccccccccccccccHHHcccccccEEEcccccccccccccHHHHcccccccEEEcccHHHHHHHHHHEEcHHHHcccccccccccccccHHHHcccccccccccccccccccccccccccccccccHHHcccccccccccccccccccccccHHHHHHHcccccccccccccccccEEcccccccHHHcccccccccc 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