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Agrobacterium tumefaciens str. C58 (atum0)
Chromosome : circular
Gene : hemC
DDBJ      :hemC         porphobilinogen deaminase
Swiss-Prot:HEM3_AGRT5   RecName: Full=Porphobilinogen deaminase;         Short=PBG;         EC=2.5.1.61;AltName: Full=Hydroxymethylbilane synthase;         Short=HMBS;AltName: Full=Pre-uroporphyrinogen synthase;

Homologs  Archaea  56/68 : Bacteria  751/915 : Eukaryota  184/199 : Viruses  0/175   --->[See Alignment]
c.94.1d.50.2
:309 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->296 1pdaA PDBj 3e-57 45.9 %
:RPS:PDB   4->306 3ecrB PDBj 1e-88 36.7 %
:RPS:SCOP  4->221 1ah5A1  c.94.1.1 * 3e-74 48.5 %
:RPS:SCOP  222->306 1ah5A2  d.50.2.1 * 3e-20 29.4 %
:HMM:SCOP  3->221 1pdaA1 c.94.1.1 * 1.3e-77 54.4 %
:HMM:SCOP  222->311 1gtkA2 d.50.2.1 * 7.1e-22 38.9 %
:RPS:PFM   5->219 PF01379 * Porphobil_deam 4e-55 59.2 %
:RPS:PFM   230->298 PF03900 * Porphobil_deamC 9e-07 40.6 %
:HMM:PFM   6->218 PF01379 * Porphobil_deam 1.8e-74 53.6 211/214  
:HMM:PFM   229->299 PF03900 * Porphobil_deamC 8.8e-21 40.8 71/76  
:BLT:SWISS 1->309 HEM3_AGRT5 e-176 100.0 %
:PROS 233->249|PS00533|PORPHOBILINOGEN_DEAM

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAK88374.1 GT:GENE hemC GT:PRODUCT porphobilinogen deaminase GT:DATABASE GIB00072CH01 GT:ORG atum0 GB:ACCESSION GIB00072CH01 GB:CHROMOSOME circular GB:LOCATION 2635681..2636610 GB:FROM 2635681 GB:TO 2636610 GB:DIRECTION + GB:GENE hemC GB:PRODUCT porphobilinogen deaminase GB:PROTEIN_ID AAK88374.1 GB:DB_XREF GI:15157859 GB:GENE:GENE hemC LENGTH 309 SQ:AASEQ MQTKPFRIGTRGSPLALAQAYETRSRLMAAHGLPEEMFEIVVLSTKGDRITDRALSEIGGKGLFTEELENQLLSGELDIAVHSSKDMPTVLPEGLHLSAFLPREDMRDAFIGRTAPKLLELPQGAVVGSASLRRQALIRRLRPDLNVIVFRGLVDTRLRKLEEGQADATLLAFAGLKRLGKDNVPTEILDPKEFPPAPAQGAIGVESRIGDARMDKLLAPINDRPTYDAVTCERAFLAALDGSCRTPIAGYATCEGDNLHFSGLILTPDGQTSHGVEISGNRRDALILGKKAGEEVRAKAGSNFFEGWS GT:EXON 1|1-309:0| SW:ID HEM3_AGRT5 SW:DE RecName: Full=Porphobilinogen deaminase; Short=PBG; EC=2.5.1.61;AltName: Full=Hydroxymethylbilane synthase; Short=HMBS;AltName: Full=Pre-uroporphyrinogen synthase; SW:GN Name=hemC; OrderedLocusNames=Atu2652; ORFNames=AGR_C_4808; SW:KW Complete proteome; Porphyrin biosynthesis; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->309|HEM3_AGRT5|e-176|100.0|309/309| GO:SWS:NREP 2 GO:SWS GO:0006779|"GO:porphyrin biosynthetic process"|Porphyrin biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 233->249|PS00533|PORPHOBILINOGEN_DEAM|PDOC00461| BL:PDB:NREP 1 BL:PDB:REP 7->296|1pdaA|3e-57|45.9|279/296| RP:PDB:NREP 1 RP:PDB:REP 4->306|3ecrB|1e-88|36.7|286/310| RP:PFM:NREP 2 RP:PFM:REP 5->219|PF01379|4e-55|59.2|213/214|Porphobil_deam| RP:PFM:REP 230->298|PF03900|9e-07|40.6|69/75|Porphobil_deamC| HM:PFM:NREP 2 HM:PFM:REP 6->218|PF01379|1.8e-74|53.6|211/214|Porphobil_deam| HM:PFM:REP 229->299|PF03900|8.8e-21|40.8|71/76|Porphobil_deamC| GO:PFM:NREP 4 GO:PFM GO:0004418|"GO:hydroxymethylbilane synthase activity"|PF01379|IPR000860| GO:PFM GO:0033014|"GO:tetrapyrrole biosynthetic process"|PF01379|IPR000860| GO:PFM GO:0004418|"GO:hydroxymethylbilane synthase activity"|PF03900|IPR000860| GO:PFM GO:0033014|"GO:tetrapyrrole biosynthetic process"|PF03900|IPR000860| RP:SCP:NREP 2 RP:SCP:REP 4->221|1ah5A1|3e-74|48.5|204/205|c.94.1.1| RP:SCP:REP 222->306|1ah5A2|3e-20|29.4|85/94|d.50.2.1| HM:SCP:REP 3->221|1pdaA1|1.3e-77|54.4|217/217|c.94.1.1|1/1|Periplasmic binding protein-like II| HM:SCP:REP 222->311|1gtkA2|7.1e-22|38.9|90/0|d.50.2.1|1/1|Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain| OP:NHOMO 1075 OP:NHOMOORG 991 OP:PATTERN 11-1-11111111111-1111111111111111111111111111111111111-------111--11 1111111111111111111-111111111111111111111111111111111111111111111112211--------111111111----1------111111111111111111111----11111111111111111---11111111111111111111111111111111111111111111---11111111111111111111111111111111111111111111111111111111111111-------------11---------------------------------------------1---------11111111111111111111111211---1111111111-11111-1-111111111-----1-1111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111---11111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-----11111111111111111111111111111111111111111111112111111111111111111111111111-111111---------------------------------------11-----111 11--111-1---1111111123232321111113211111111111112211211111111111111111111111111111111111-12111121-11111231-11-211124-1121111121413F2-11111111111111212111111112211121-11111--111221G1111131221111111142 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 303 STR:RPRED 98.1 SQ:SECSTR ###ccEEEEEcccHHHHHHHHHHHHHHHHHcTcEEEEEEccEcccHHTccEEEEEccTTccHHHHHHHHHHHHTTcccEEEEEGGGccccccTTEEEEEEcccccccEEEEEcTTccTTTccTTcEEEcccHHHHHHHHHHcTTcEEEcccccHHHHHHHHHHccccEEEEEHHHHHHTTcGGGccEEccTTTccccTTTTcEEEEEETTcHHHHHHHGGGccHHHHHHHHHHHHHHHHHHHcccccEEEEEEEETTEEEEEEEEEcTTcccEEEEEEHHHHHHHHHHHHHHHHHHHHTTHHHHHH### DISOP:02AL 1-2| PSIPRED ccccEEEEEEcccHHHHHHHHHHHHHHHHHHcccccEEEEEEEEEEccccccccHHHHcccEEEHHHHHHHHHcccccEEEEcccccccccccccEEEEEcccccccEEEEEcccccHHHcccccEEEEcHHHHHHHHHHHccccEEEEccccHHHHHHHHHcccccHHHHHHHHHHHccccccccEEEcHHHccccccccEEEEEEEccHHHHHHHHHHHccHHHHHHHHHHHHHHHHHcccccccEEEEEEEEccEEEEEEEEEcccccEEEEEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHcccc //