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Agrobacterium tumefaciens str. C58 (atum0)
Chromosome : circular
Gene : leuC
DDBJ      :leuC         3-isopropylmalate dehydratase, large subunit
Swiss-Prot:LEUC_AGRT5   RecName: Full=3-isopropylmalate dehydratase large subunit;         EC=4.2.1.33;AltName: Full=Isopropylmalate isomerase;AltName: Full=Alpha-IPM isomerase;         Short=IPMI;

Homologs  Archaea  60/68 : Bacteria  772/915 : Eukaryota  155/199 : Viruses  0/175   --->[See Alignment]
c.83.1
:469 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   89->446 1c97A PDBj 1e-19 27.6 %
:RPS:PDB   1->469 2b3yA PDBj e-131 21.7 %
:RPS:SCOP  1->469 2b3xA2  c.83.1.1 * e-129 21.9 %
:HMM:SCOP  3->471 2b3yA2 c.83.1.1 * 7.3e-177 42.4 %
:RPS:PFM   62->450 PF00330 * Aconitase 1e-51 36.7 %
:HMM:PFM   6->460 PF00330 * Aconitase 9.2e-182 49.9 453/465  
:BLT:SWISS 1->469 LEUC_AGRT5 0.0 100.0 %
:PROS 342->358|PS00450|ACONITASE_1
:PROS 402->415|PS01244|ACONITASE_2
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAK88428.2 GT:GENE leuC GT:PRODUCT 3-isopropylmalate dehydratase, large subunit GT:DATABASE GIB00072CH01 GT:ORG atum0 GB:ACCESSION GIB00072CH01 GB:CHROMOSOME circular GB:LOCATION 2693584..2694993 GB:FROM 2693584 GB:TO 2694993 GB:DIRECTION + GB:GENE leuC GB:PRODUCT 3-isopropylmalate dehydratase, large subunit GB:PROTEIN_ID AAK88428.2 GB:DB_XREF GI:159140593 GB:GENE:GENE leuC LENGTH 469 SQ:AASEQ MSAPRTLYDKIWDDHVVNRDPDGTCLLYIDRHLVHEVTSPQAFEGLRIAGRPVHSPTRTLAVVDHNVPTTADRLEGIKNEESRIQVEALAQNAKEFGVEYYSERDKRQGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMLVRVDGKLPESVTAKDIILAIIGEIGTAGGTGHVIEFAGEAIRSLSMEGRMTVCNMTIEGGARAGLIAPDETTFDYIKDKPRAPKGETLEQAIAYWKTLKSDEGAHYDKVVILDAANLPPIVSWGSSPEDVTSVEGIVPNPDDIEEENKRTSKWRALDYMGLKPGTRITDIAIDRVFIGSCTNGRIEDLRAAAKIVDGRKVASTVSAMIVPGSGLVKEQAEKEGLDKIFLDAGFEWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGYKSRTHLVSPAMAAAAAIAGHFVDVREWQ GT:EXON 1|1-469:0| SW:ID LEUC_AGRT5 SW:DE RecName: Full=3-isopropylmalate dehydratase large subunit; EC=4.2.1.33;AltName: Full=Isopropylmalate isomerase;AltName: Full=Alpha-IPM isomerase; Short=IPMI; SW:GN Name=leuC; OrderedLocusNames=Atu2709; ORFNames=AGR_C_4910; SW:KW 4Fe-4S; Amino-acid biosynthesis;Branched-chain amino acid biosynthesis; Complete proteome; Iron;Iron-sulfur; Leucine biosynthesis; Lyase; Metal-binding. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->469|LEUC_AGRT5|0.0|100.0|469/469| GO:SWS:NREP 7 GO:SWS GO:0051539|"GO:4 iron, 4 sulfur cluster binding"|4Fe-4S| GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0009082|"GO:branched chain family amino acid biosynthetic process"|Branched-chain amino acid biosynthesis| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0009098|"GO:leucine biosynthetic process"|Leucine biosynthesis| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| PROS 342->358|PS00450|ACONITASE_1|PDOC00423| PROS 402->415|PS01244|ACONITASE_2|PDOC00423| SEG 186->201|iilaiigeigtaggtg| SEG 451->459|amaaaaaia| BL:PDB:NREP 1 BL:PDB:REP 89->446|1c97A|1e-19|27.6|326/753| RP:PDB:NREP 1 RP:PDB:REP 1->469|2b3yA|e-131|21.7|465/888| RP:PFM:NREP 1 RP:PFM:REP 62->450|PF00330|1e-51|36.7|368/434|Aconitase| HM:PFM:NREP 1 HM:PFM:REP 6->460|PF00330|9.2e-182|49.9|453/465|Aconitase| GO:PFM:NREP 1 GO:PFM GO:0008152|"GO:metabolic process"|PF00330|IPR001030| RP:SCP:NREP 1 RP:SCP:REP 1->469|2b3xA2|e-129|21.9|465/629|c.83.1.1| HM:SCP:REP 3->471|2b3yA2|7.3e-177|42.4|465/0|c.83.1.1|1/1|Aconitase iron-sulfur domain| OP:NHOMO 2364 OP:NHOMOORG 987 OP:PATTERN 11-2--2111111122-2222222311222422222222222222222332222221-1--3112-23 1322311111121112211-111114111111111111332111113--111111121--111312211122222222-111322222222212---1111213312232---------------22231122223322332224222222222211112112222222322222222222223233322121222222222122222211222222211122112111211212222222222222222222-------1------------111212-------222------------------------222222122-23-22111111121232221---2-21-2322222222221222222--2-22322211111423332222222222222222222-22422522222122232222223221542333222222322222222111213221111111111--1-111111111111111222422575353334345333344563333-353665761155422223323234333222253223333311133222311222222222-222222333332312231222222223-1211111111222222221333334433222222323323233233-1-4421-11--142433344444444444-4434443444444334436343333434343434443434334332244442-333333333333111411111111124312111112-11111111222222233341222224443223233332-1-11-1-222222222223333442222233333331121332222-------------------------------------12--2-222211 ----223-21--2246442655557644434444434444444444334655865455444444444434454455413444444444-34444455554344656-224325111--1--------1-------2--------1--------1--11224312211312614212222S1111243354342243331 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 469 STR:RPRED 100.0 SQ:SECSTR ccccHHHHHHHHTHHHHTTTTTcEEEEcccEEEEEHHHHHHHHHHHHHHHHHccccccEEEEcccccccccHHHHHHHHHHHHHHHHHHHHHHHHcTTEEEETTcTTcccHHcEEEETTEEEEccEEEEccGGGGGGGGGTcEEEEccHHHHHHHHTTccEEEEcccEEEEEEEccccTTccHHHHHHHHHHHHHHHccTTcEEEEEcGGGTTccHHHHHHHHHTHHHHTccEEEccccHHHHHHHHHTTccHHHHHHHHHHTccccTTcGGcccccEEEEEEGGGcccEEEccccTTcEEEGGGHHHHHHHHHHcccGGGTTcEEEEEETTEEEEEETTcEEEEEEccHHHHTcHHHHHHHHHHHHccccTTcEEEEccccHHHHHHHHHTccHHHHHHTTccccccccGGGGTccccccHHHHHEEEccccccTTcccTTccEEEccHHHHHHHHHHccccccTTTc DISOP:02AL 1-1,467-467| PSIPRED cccccHHHHHHHHHHHcccccccEEEEEEEEEEEEcccHHHHHHHHHHccccccccccEEEEEccccccccccccccccHHHHHHHHHHHHHHHHHcccccccccccccEEEEEEccccEEcccEEEEEcccccccccccccEEEcccHHHHHHHHHcccEEEccccEEEEEEEEEccccccHHHHHHHHHHHHccccccEEEEEEEcccHHcccHHHHHHHHHHHHHHccEEEEccccHHHHHHHHHccccHHHHHHHHHHHHHccccccccccccEEEEEEHHHccEEEccccccccEEEHHHHcccHHHHHHHHHHccccccHHHccccccccccccEEEEEEEEcccccccHHHHHHHHHHccccccccccEEEEcccHHHHHHHHHcccHHHHHHcccEEEccccHHHccccccccccccEEEEEccccccccccccccEEEccHHHHHHHHHHcccccHHHHc //