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Agrobacterium tumefaciens str. C58 (atum0)
Chromosome : circular
Gene : nrdE.2
DDBJ      :nrdE         ribonucleoside-diphosphate reductase 2 alpha chain
Swiss-Prot:NRDJ_AGRT5   RecName: Full=Vitamin B12-dependent ribonucleotide reductase;         EC=1.17.4.1;AltName: Full=Ribonucleoside-diphosphate reductase nrdJ;

Homologs  Archaea  46/68 : Bacteria  391/915 : Eukaryota  120/199 : Viruses  4/175   --->[See Alignment]
c.7.1
:1272 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   136->297,404->754,865->917 1xjnB PDBj 3e-25 33.0 %
:RPS:PDB   24->778 2cvtA PDBj e-100 21.5 %
:RPS:PDB   831->917 2bq1E PDBj 1e-13 24.1 %
:RPS:SCOP  65->774 1l1lA  c.7.1.4 * e-100 13.1 %
:RPS:SCOP  833->926 1l1lA  c.7.1.4 * 3e-17 14.7 %
:HMM:SCOP  196->927 1rlrA2 c.7.1.2 * 1.2e-124 36.8 %
:RPS:PFM   31->147 PF08471 * Ribonuc_red_2_N 2e-34 76.4 %
:RPS:PFM   198->299,395->721,863->908 PF02867 * Ribonuc_red_lgC 4e-61 47.3 %
:RPS:PFM   337->380 PF01709 * DUF28 2e-04 38.6 %
:HMM:PFM   198->746 PF02867 * Ribonuc_red_lgC 4.8e-111 35.2 432/533  
:HMM:PFM   825->914 PF02867 * Ribonuc_red_lgC 1.9e-17 32.9 82/533  
:HMM:PFM   31->147 PF08471 * Ribonuc_red_2_N 2.6e-40 65.6 93/93  
:BLT:SWISS 1->1272 NRDJ_AGRT5 0.0 100.0 %
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAK87503.1 GT:GENE nrdE.2 GT:PRODUCT ribonucleoside-diphosphate reductase 2 alpha chain GT:DATABASE GIB00072CH01 GT:ORG atum0 GB:ACCESSION GIB00072CH01 GB:CHROMOSOME circular GB:LOCATION 1717324..1721142 GB:FROM 1717324 GB:TO 1721142 GB:DIRECTION + GB:GENE nrdE GB:PRODUCT ribonucleoside-diphosphate reductase 2 alpha chain GB:PROTEIN_ID AAK87503.1 GB:DB_XREF GI:15156830 GB:GENE:GENE nrdE LENGTH 1272 SQ:AASEQ MRIERRFTKPGQSSYAEIEFRKAVSEIKNPDGSVVFRLADIDVPAQFSQVATDVLAQKYFRKAGVPKLLKKVEENDVPSFLWRSVADEKALKELPEAERYGSETDARQVFDRLAGTWAYWGWKGKYFSTEEDASAFKDELAYMLATQRVAPNSPQWFNTGLHWAYGIDGPGQGHFYVDPFTGKLTKSKSAYEHPQPHACFIQSVEDDLVNEGGIMDLWVREARLFKYGSGTGSNFSYLRGEGEKLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIEAYIDWKVNEEQKVAALVTGSKIVAKHLKAIMKACVNCEADNGDCFDPAKNPALKREIRAAKKDMVPENYVKRVIQFAEQGYKDIQFKTYDTDWDSEAYLTVSGQNSNNSVSLKDDFLRAVENDGNWNLTARKDGKVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWHTSPAEGPIRASNPCSEYMFLDDTACNLASLNLLQFKDAKTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSYEYRTLGLGYANIGGLLMSSGIPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSFAPNRDNMLRVIRNHRRAAHGQSEGYEGLSVNPVALIHADCTDQDLVAHATAAWDKALELGEKHGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPESLRSLGYSESQIAEIEAYAVGHGNLNQAPAINPSTLKAKGFTDEKIEAVNAALKSAFDIKFVFNQWTLGADFLKGTLKVSDEQLSDMSFNLLDHLGFAKKDIEAANVHVCGAMTLEGAPFLKNEHLAVFDCANPCGKIGKRYLSVESHIRMMAAAQPFISGAISKTINMPNDATVEDCGAAYMLSWKLALKANALYRDGSKLSQPLNASLVEDEDDEDFVEELIQQPLAQQAVTITEKIVERVIERVSREREKLPNRRQGYTQKATVGGHKVYLRTGEFGDGRIGEIFIDMHKEGAAFRAMMNNFAIAISLGLQYGVPLEEYVEAFTFTKFEPAGMVQGNDAIKNATSILDYVFRELAVSYLGRHDLAHVDTSDFSNTALGKGIQEGKTNLLSTGWTRGYKPTLVSSNEGDRAASEPKGSATAAPARGSANVTSFAGSAARKLEPTVAITTSEIVSFKRDYEERAKELAEEIAEEVIDEVVQEAQQTATALFSDKAAADAASAKAEAKKKENERRMRSIAQGYTGNMCSECQNFTMVRNGTCEKCDTCGATSGCS GT:EXON 1|1-1272:0| SW:ID NRDJ_AGRT5 SW:DE RecName: Full=Vitamin B12-dependent ribonucleotide reductase; EC=1.17.4.1;AltName: Full=Ribonucleoside-diphosphate reductase nrdJ; SW:GN Name=nrdJ; OrderedLocusNames=Atu1733; ORFNames=AGR_C_3183; SW:KW Cobalamin; Cobalt; Complete proteome; DNA synthesis;Nucleotide-binding; Oxidoreductase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1272|NRDJ_AGRT5|0.0|100.0|1272/1272| GO:SWS:NREP 5 GO:SWS GO:0031419|"GO:cobalamin binding"|Cobalamin| GO:SWS GO:0006260|"GO:DNA replication"|DNA synthesis| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| COIL:NAA 33 COIL:NSEG 1 COIL:REGION 1200->1232| SEG 240->254|gegeklsgggkssgl| SEG 928->939|vededdedfvee| SEG 950->970|vtitekiverviervsrerek| SEG 1179->1203|eerakelaeeiaeevidevvqeaqq| SEG 1210->1228|sdkaaadaasakaeakkke| BL:PDB:NREP 1 BL:PDB:REP 136->297,404->754,865->917|1xjnB|3e-25|33.0|502/610| RP:PDB:NREP 2 RP:PDB:REP 24->778|2cvtA|e-100|21.5|576/637| RP:PDB:REP 831->917|2bq1E|1e-13|24.1|79/675| RP:PFM:NREP 3 RP:PFM:REP 31->147|PF08471|2e-34|76.4|89/89|Ribonuc_red_2_N| RP:PFM:REP 198->299,395->721,863->908|PF02867|4e-61|47.3|442/506|Ribonuc_red_lgC| RP:PFM:REP 337->380|PF01709|2e-04|38.6|44/234|DUF28| HM:PFM:NREP 3 HM:PFM:REP 198->746|PF02867|4.8e-111|35.2|432/533|Ribonuc_red_lgC| HM:PFM:REP 825->914|PF02867|1.9e-17|32.9|82/533|Ribonuc_red_lgC| HM:PFM:REP 31->147|PF08471|2.6e-40|65.6|93/93|Ribonuc_red_2_N| GO:PFM:NREP 6 GO:PFM GO:0004748|"GO:ribonucleoside-diphosphate reductase activity"|PF08471|IPR013678| GO:PFM GO:0050897|"GO:cobalt ion binding"|PF08471|IPR013678| GO:PFM GO:0055114|"GO:oxidation reduction"|PF08471|IPR013678| GO:PFM GO:0004748|"GO:ribonucleoside-diphosphate reductase activity"|PF02867|IPR000788| GO:PFM GO:0005971|"GO:ribonucleoside-diphosphate reductase complex"|PF02867|IPR000788| GO:PFM GO:0006260|"GO:DNA replication"|PF02867|IPR000788| RP:SCP:NREP 2 RP:SCP:REP 65->774|1l1lA|e-100|13.1|612/717|c.7.1.4| RP:SCP:REP 833->926|1l1lA|3e-17|14.7|86/717|c.7.1.4| HM:SCP:REP 196->927|1rlrA2|1.2e-124|36.8|475/525|c.7.1.2|1/1|PFL-like glycyl radical enzymes| OP:NHOMO 681 OP:NHOMOORG 561 OP:PATTERN 11---11111111111-11-11-1111-1211-----------1111-1-111-11111111111-11 21112------------11-1-11--11111-1111----1222---2-111--------22121222222----111----1--221----1---1----11221111111111111111111111111111111111--323121-----------------1------------------11---11----------1-----1---1--------1-1---------12-------------------------------------------------------------------1111111111111-------------1-----------11-------11--1---1----1-1111111-1--1313114-----111112221111111111111111-11112111113-21111111111111232222222221222222222322112231111111111111---11111----11112-11--1-------1---------111111-1-2112221-22221-11112211111111111--------1-111111-1111111111-11111121122222221---------------------------11--2-----------------------------112-------------1--11----1--11---------111111-111------1-------1-------------------------------------------12----------------111111----1-22221-11-1-112---111111111-1--1----------11--------------1-111111---1--1--------------------1--------1-111111111-1 1111--1-211-11-1111111111111111111111111--11111111111111111111-112-21-12-1-22122111111----11111-11111-142311111--------------------------------1---------2-----13411-1-11--1--11------11-112111--211111 ----------------1-------------------------------------------------------------------------------------------------1--------------------------------------------------------1-1- STR:NPRED 880 STR:RPRED 69.2 SQ:SECSTR ##############HHHHHHG#GHHHHHHTTHHHHHHHccGGGGGcccHHHHHHHHHHTcccccHHHHHHHHHHTTccccEEEEEEccccccccHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHccccHHHHHHHHHcHHHHHHTTcEEEcHHHHHHTTcHHHHTTcHHHHHHHHHHHHTTcEEEcHHHHccccccccEEEEccccHHcHHHHHHHHHHHHHTTTccccEEEEcTTcccTTccccccccccccHHHHHHHHHHHHHTTTTTTcccccEEEEEcTTcTTHHHHHHTTccccTTccccTT##TTccTTETHHEEEEE#######HHcEEEEEEEEEEEEE#####EEcHHHHHHHHT##HTTcEEccccTTTcTTTTTccHTcEEEcHHHHHHHHHHHGGGccccTHHHHHHHHHTTccccEEHHHHHHHHHHHHHHHcccEEEEHHHHHHTcTTTTTcccccccccTTccccccTEccEEEEETTTTEEccccEEcHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHcccEEEEEcHHHHHHHTTccTTcTTHHHHHHHHHHHHHHHHHHHHHHHHHHHcccTTcTTcTHHGGGTccHHHHGGGT#ccGcccTTccccHHHHHHHHHHTccccccccHHHHHHHHHHHccccccccccccccccccHHHHHHHHHccccTTcccHHHHccccccccTTccHHHHcccTTTccHHHHHHHHHHHGHHccccGGcccccccccccccccTTHHHHHHHHHHHTTcEEcGGGGcGGGTTTTcccccccccHHHHHHHHHHHTTcEEEEcccEEEccEEccccHHHHcccEEEEEEEcTTc#####GTccHHHHHHHHHHHGGGccccccccccccTcccTTHHHHHHHHHHHTTcccccccEEcc################################################################################################################################################################################################################################################################################################################################################################### DISOP:02AL 1-3, 1115-1139, 1218-1234| PSIPRED cccccEEEccccccHHHHHHHccccHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHccccccccHHHHHHHHHHHHHHcccHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHccEEEcccccEEEccccccccccEEEEEEcccccccHHHHHHHHHHHHHHHHHHcccEEEEcccccccccccccccccccccHHHHHHHHHHHHHHHccccccccEEEEEEccHHHHHHHHHcccccccHHHHHHHHccccHHHHHHHHHHHHccccccEEEccccccccHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEcccccEEEEHHHHHHHHHccccEEEEccccccEEEEEcHHHHHHHHHHHHHcccccEEEEEcccccccccHHcccEEEccccccccccccccccHHHHHHHHHcccccccccHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHcccEEEEHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHHHHHHHHHHHHccHHccccccccccccHHHHHHHHHcccccccHHHHHHHHHHHHHccccEEEEEEEccHHHHHHHHcccccccccccEEEEEEEEEcccEEEEEcHHHHHHHHHHcccHHHHHHHHHHHHHHccccccccccHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHccccHHHHHHHHHHHHHcccccccccccHHHHHHHHHcccccccccccccHHHHHHHHHHHHHHHcccccEEEEccccccHHHHHHHHHHHHHccccEEEEEEccccccccccccccccccccccccccHHHHHccccccccHHHHHHHHHHccccccccccccccEEEEEEEccEEEEEEEEEEccccEEEEEEcccccccHHHHHHHHHHHHHHHHHHccccHHHHHHHHHccccccccEEccccccEEHHHHHHHHHHHHHHHHcccccccccccccccccHHHccccccccccHHHccccccccccEEccccccccccccccccccccccccccEEEEcccHHHccccHHHHHcccccccccHHHHHccccHHHHHHHccHHHHHHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHccccccccccccccEEEEEcccccEEcccccccccc 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