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Agrobacterium tumefaciens str. C58 (atum0)
Chromosome : circular
Gene : thyA
DDBJ      :thyA         thymidylate synthase
Swiss-Prot:TYSY_AGRT5   RecName: Full=Thymidylate synthase;         Short=TS;         Short=TSase;         EC=2.1.1.45;

Homologs  Archaea  16/68 : Bacteria  608/915 : Eukaryota  181/199 : Viruses  12/175   --->[See Alignment]
d.117.1
:264 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   1->250 3ix6B PDBj e-118 81.4 %
:RPS:PDB   1->264 1bq2A PDBj e-121 59.8 %
:RPS:SCOP  2->264 1aiqA  d.117.1.1 * e-123 59.7 %
:HMM:SCOP  1->264 1qzfA2 d.117.1.1 * 1.2e-137 64.8 %
:RPS:PFM   1->263 PF00303 * Thymidylat_synt e-116 70.7 %
:HMM:PFM   2->264 PF00303 * Thymidylat_synt 5.1e-125 66.2 263/266  
:BLT:SWISS 1->264 TYSY_AGRT5 e-147 100.0 %
:PROS 126->154|PS00091|THYMIDYLATE_SYNTHASE
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID AAK87800.2 GT:GENE thyA GT:PRODUCT thymidylate synthase GT:DATABASE GIB00072CH01 GT:ORG atum0 GB:ACCESSION GIB00072CH01 GB:CHROMOSOME circular GB:LOCATION complement(2005855..2006649) GB:FROM 2005855 GB:TO 2006649 GB:DIRECTION - GB:GENE thyA GB:PRODUCT thymidylate synthase GB:PROTEIN_ID AAK87800.2 GB:DB_XREF GI:159140300 GB:GENE:GENE thyA LENGTH 264 SQ:AASEQ MKQYLDLLRHVMETGSDRGDRTGTGTRSVFGYQMRFDLSEGFPVLTTKKLHLRSIIHELLWFLNGDTNIAYLKENGVSIWDEWADENGDLGPVYGAQWRSWPAPDGRHIDQIALLIEALKTNPNSRRHIVSAWNPALVDEMALPPCHCLFQFYVSDGKLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVVGLKPGDFVHTLGDAHIYANHFEQAQLQMTRTPKALPTMRLNPDVKNLFGFKFEDFTLENYEADSSIKAPIAV GT:EXON 1|1-264:0| SW:ID TYSY_AGRT5 SW:DE RecName: Full=Thymidylate synthase; Short=TS; Short=TSase; EC=2.1.1.45; SW:GN Name=thyA; OrderedLocusNames=Atu2047; ORFNames=AGR_C_3709; SW:KW Complete proteome; Cytoplasm; Methyltransferase;Nucleotide biosynthesis; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->264|TYSY_AGRT5|e-147|100.0|264/264| GO:SWS:NREP 4 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0008168|"GO:methyltransferase activity"|Methyltransferase| GO:SWS GO:0009165|"GO:nucleotide biosynthetic process"|Nucleotide biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 126->154|PS00091|THYMIDYLATE_SYNTHASE|PDOC00086| TM:NTM 1 TM:REGION 170->192| SEG 14->28|tgsdrgdrtgtgtrs| BL:PDB:NREP 1 BL:PDB:REP 1->250|3ix6B|e-118|81.4|242/248| RP:PDB:NREP 1 RP:PDB:REP 1->264|1bq2A|e-121|59.8|264/264| RP:PFM:NREP 1 RP:PFM:REP 1->263|PF00303|e-116|70.7|263/264|Thymidylat_synt| HM:PFM:NREP 1 HM:PFM:REP 2->264|PF00303|5.1e-125|66.2|263/266|Thymidylat_synt| GO:PFM:NREP 2 GO:PFM GO:0004799|"GO:thymidylate synthase activity"|PF00303|IPR000398| GO:PFM GO:0006231|"GO:dTMP biosynthetic process"|PF00303|IPR000398| RP:SCP:NREP 1 RP:SCP:REP 2->264|1aiqA|e-123|59.7|263/265|d.117.1.1| HM:SCP:REP 1->264|1qzfA2|1.2e-137|64.8|264/341|d.117.1.1|1/1|Thymidylate synthase/dCMP hydroxymethylase| OP:NHOMO 908 OP:NHOMOORG 817 OP:PATTERN ---------------------------11-11------1--111111-11111--------------- ----111111111111111-11112111111111111111----11111--1121111----11-------11111111---------111111111--11111111111-------------------------------------------------------------------------1-1------11111111111111111111112111111111111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111---11-------2-11---------1--1-1----1------------11--1211111111111111111111311111111111-111111111111111111111111-1111---111111--------------11-------------------------------11111111111111111111111111111111121111111111211111121111112111111111111111111---------------------------1------------------------------1111111111111111111111111111111-1111111-11111111111111111111-11111111111111111111111111111111111211211112111111111111111111111--1111111111111111111111111111111111112111111111111111112111111111111111111111111111111111111111111111-1----------------111111------11---1-1111-------------1-1 1111--1-311-11211111111111-11111111-1211-111111111111111111111111111111111111-1111111111-1211111111111111131211211-1411-111111331381-31411-15112-111111--21121223111121111-11211121M1111112-51312111111 ---1---------------1-1-------------111-1--------------------------------------------------------------------------1---------------------------------------------1---1-----1-1-- STR:NPRED 264 STR:RPRED 100.0 SQ:SECSTR cHHHHHHHHHHHHHcEEEEcTTccEEEEEEEEEEEEEGGGcccccTTTTccHHHHHHHHHHHHTTcccTHHHHTTTccTTTTTccTTccccccHHHHHHcEEcTTccEEcHHHHHHHHHHHcTTccccEEEcccGGGGGGccccccccEEEEEEETTEEEEEEEEEEEETTTHHHHHHHHHHHHHHHHHHHTTcEEEEEEEEEEEEEEEGGGHHHHHHHTTcccccccEEEEccccccGGGccGGGEEEEcccccccccccccc PSIPRED cHHHHHHHHHHHHccEEccccccccEEEEEccEEEEEcccccEEEEEcccHHHHHHHHHHHHHcccccHHHHHHHcccEEHHHHHHcccccccHHHHHHHccccccccccHHHHHHHHHHccccccEEEEEEccHHHHHHccccccEEEEEEEEEccEEEEEEEEEEcccHHHHHHHHHHHHHHHHHHHHHHccccEEEEEEEEEEEEcHHHHHHHHHHHccccccccEEEEccccccHHHcccccEEEEcccccccccccccc //