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Bacteriophage 44RR2.8t (bp441)
Gene : 52
DDBJ      :52           topoisomerase II medium subunit
Swiss-Prot:             

Homologs  Archaea  22/68 : Bacteria  908/915 : Eukaryota  195/199 : Viruses  9/175   --->[See Alignment]
e.11.1
:555 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   90->505 1bjtA PDBj 2e-38 29.7 %
:RPS:PDB   133->550 1ab4A PDBj 2e-59 24.3 %
:RPS:SCOP  133->550 1ab4A  e.11.1.1 * 3e-60 24.3 %
:HMM:SCOP  90->553 1bjtA_ e.11.1.1 * 1.3e-100 28.2 %
:RPS:PFM   134->525 PF00521 * DNA_topoisoIV 2e-35 32.4 %
:HMM:PFM   134->548 PF00521 * DNA_topoisoIV 6.8e-92 32.2 395/426  
:BLT:SWISS 109->553 TOP5_BPT4 e-116 47.0 %

SeqInfo AminoSeq See neighboring genes
Links DAD DDBJ Abbreviations Back to title page
GT:ID AAQ81559.1 GT:GENE 52 GT:PRODUCT topoisomerase II medium subunit GT:DATABASE AY375531 GT:ORG bp441 GB:ACCESSION AY375531 GB:LOCATION complement(167065..168732) GB:FROM 167065 GB:TO 168732 GB:DIRECTION - GB:GENE 52 GB:PRODUCT topoisomerase II medium subunit GB:NOTE similar to T4 accession NP_049875.1; gp52 GB:PROTEIN_ID AAQ81559.1 GB:DB_XREF GI:34733022 GB:GENE:GENE 52 LENGTH 555 SQ:AASEQ MNFSLDAFFDEEPASPAQKQTSNPETPPWDVEVDLTLGAKEDVWFAPAGYQRGLIEVEPGDTGEIEVIEPMEHPTEDEVISEQIRQCEDALAQEIPAWKRTILSNHLTELHNRSLQSIINHEALEFAMYTVEERAIPSLIDGLKPVQRFFMYRALEYAKQNRSKFNKVAALAGGVSEAGYHHGEGSAAGAGQLIANTWNNNIPILEGDGNFGSRMVQQAAAPRYVFCRVHQNFWDIYRDIELAPVHPEPEHLPPRYYLPVIPMVLANGVKGIATGYATNIFPHSYKSLIKCTKAAIEGKPIPRLEVQFPEFSGVIRRVSAKTIEVEGLYELSGQTKLTITELPVKFDRLSYVILLDKLKDQGKIVSYKEQHKNGFRFDVTLKRQDKFGEQLQNNPEATHEKIIKMFGLRQVLTQNITVLNPEGKLAEYECAEDVIRDFVEHRRKFTAERVEYERQKSEHARDLAWAKFKFINMVIDDKITIKGKQKAELVKEIASNPDFKGFENELVGMSIYRMTEDETYKLQDEAIKQGKLFDYWLGTTPEAEYINDLNSLKGK GT:EXON 1|1-555:0| BL:SWS:NREP 1 BL:SWS:REP 109->553|TOP5_BPT4|e-116|47.0|440/442| BL:PDB:NREP 1 BL:PDB:REP 90->505|1bjtA|2e-38|29.7|401/679| RP:PDB:NREP 1 RP:PDB:REP 133->550|1ab4A|2e-59|24.3|391/477| RP:PFM:NREP 1 RP:PFM:REP 134->525|PF00521|2e-35|32.4|373/434|DNA_topoisoIV| HM:PFM:NREP 1 HM:PFM:REP 134->548|PF00521|6.8e-92|32.2|395/426|DNA_topoisoIV| GO:PFM:NREP 5 GO:PFM GO:0003677|"GO:DNA binding"|PF00521|IPR002205| GO:PFM GO:0003918|"GO:DNA topoisomerase (ATP-hydrolyzing) activity"|PF00521|IPR002205| GO:PFM GO:0005524|"GO:ATP binding"|PF00521|IPR002205| GO:PFM GO:0005694|"GO:chromosome"|PF00521|IPR002205| GO:PFM GO:0006265|"GO:DNA topological change"|PF00521|IPR002205| RP:SCP:NREP 1 RP:SCP:REP 133->550|1ab4A|3e-60|24.3|391/477|e.11.1.1| HM:SCP:REP 90->553|1bjtA_|1.3e-100|28.2|454/760|e.11.1.1|1/1|Type II DNA topoisomerase| OP:NHOMO 1999 OP:NHOMOORG 1134 OP:PATTERN -----------------------111111111-----------1111111111--------111---- 1111211111111111112-11--1211111111211111211122221222222221222222121222222222221111111111222212222112222222222222222222222222211111111111111111111122222222222222222222222222222222222221111111112222222222222222222222222222212222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222222211122222222222221222222221111221122111121111111111112222222222222222222222222222222222-22223222222222222222222222222222222222222222222222222221111111111112222222222222111112222222222222222222222222222222232222222222222222222222221121222222222111222112121111111111111111111111122111111111111111111111111111222222222222222222222222222222221-2222211111122222222222222222-22222222222222222222222222222222222222222222222222221222222222222112222222222222222222222222112222222122222222222222222222222222222222222222222222222222222222222222222212222222222222221211112-22222222222222222231111111111122 22112211622111211111111111111111111111112111111111111111111111111111-111111111111-111111-12111111111121111114222223342221222221319K2-4262112212232221221231422213911161111444113222F2232231231233433222 ---1---------------1---------------111-1----------------------------------------------------------------------------------------------------------------------------------111-- STR:NPRED 463 STR:RPRED 83.4 SQ:SECSTR #########################################################################################THHHHHHHHHHHHHHHHHHcccccccccccTHHHHHHHHHHHHTTTcccTTTcccHHHHHHHHHHHHTTcccccccEEHHHHHHHHHHHTccccHHHHHHHHHHTTcTTTcccccEEEEcccccTTccccccTTTcEEEEcTTHHHHcTTTTTTcccEEEcTEEEccccccccHHHHHcEEEccccccEEEccccHHHHHHHHHHHHHcTTccHHHcccccccccEEcccHHHHHHEEEEEEEcEEEEEEEEccTTccHHHHHHHHHHHHTTTccccEEEcccccccEEEEccHHHEEEEEEEEccHHHHHHHHHHcTTEEEEEEEcEEEETTTTEEEEccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHTTHHHHHcccHHHHHHHHHHccEEccGGGTTcccccccTTccTTcEEcccEHHHHHHHHEEcTcHHHHHHHHTccHH### DISOP:02AL 1-1,555-556| PSIPRED cccEEEHHHccccccHHHHHHccccccccEEEEEcccccccHHHHHccHHHHHHHHHccccccHHHHHHHccccccHHHHHHHHHHccHHHHHHHHHHcccccccccccEEEccHHHHHHHHHHHHHHHHHHHHccccHHHcccHHHHHHHHHHHHcccccccccEEHHHHHHHHHHccccccHHHHHHHHHHHcccHHcccEEEccccccccccccccHHHHHHHHHHHHHHHHHHcccccccccccccccccEEEcccccEEEEEccccHHcccccccccccHHHHHHHHHHHHHcccccHHcccccccccEEEEEcccEEEEEEEEEEEcccEEEEEEccccccHHHHHHHHHHHHHccccccEEccccccEEEEEEEcccccHHHHHHccHHHHHHHHHHHccccEEEEEEEEEEEccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEccccHHHHHHHHHHccccHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHcc //