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Bacteriophage 44RR2.8t (bp441)
Gene : 60plus39
DDBJ      :60plus39     topoisomerase II large subunit
Swiss-Prot:             

Homologs  Archaea  21/68 : Bacteria  860/915 : Eukaryota  193/199 : Viruses  10/175   --->[See Alignment]
c.52.1d.122.1d.14.1e.11.1
:607 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   9->362 1zxnA PDBj 1e-30 31.0 %
:BLT:PDB   405->605 3fofD PDBj 4e-15 33.7 %
:RPS:PDB   37->149 1b1jA PDBj 2e-12 12.8 %
:RPS:PDB   288->592 1dc1B PDBj 2e-35 7.9 %
:RPS:SCOP  2->225 1pvgA2  d.122.1.2 * 2e-25 27.6 %
:RPS:SCOP  294->592 1dc1A  c.52.1.11 * 1e-33 8.5 %
:HMM:SCOP  1->230 1pvgA2 d.122.1.2 * 4.2e-40 29.2 %
:HMM:SCOP  220->371 1pvgA1 d.14.1.3 * 5.2e-28 30.9 %
:HMM:SCOP  385->607 1bjtA_ e.11.1.1 * 1e-46 29.7 %
:RPS:PFM   256->366 PF00204 * DNA_gyraseB 6e-07 33.3 %
:HMM:PFM   248->382 PF00204 * DNA_gyraseB 3.6e-31 32.8 131/173  
:HMM:PFM   45->187 PF02518 * HATPase_c 8.5e-15 27.2 103/111  
:HMM:PFM   585->605 PF00986 * DNA_gyraseB_C 0.00051 42.9 21/65  
:HMM:PFM   179->221 PF08469 * NPHI_C 0.00065 23.3 43/148  
:BLT:SWISS 1->469 TOPL_BPT4 e-136 59.9 %
:BLT:SWISS 476->607 TOPS_BPT4 4e-45 59.1 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links DAD DDBJ Abbreviations Back to title page
GT:ID AAQ81326.1 GT:GENE 60plus39 GT:PRODUCT topoisomerase II large subunit GT:DATABASE AY375531 GT:ORG bp441 GB:ACCESSION AY375531 GB:LOCATION complement(4246..6069) GB:FROM 4246 GB:TO 6069 GB:DIRECTION - GB:GENE 60plus39 GB:PRODUCT topoisomerase II large subunit GB:NOTE similar to T4 accessions NP_049618.1; NP_049621.1; in T4 an insertion splits the large topoisomerase II subunit in two parts (gp60 and gp39); gp60plus39 GB:PROTEIN_ID AAQ81326.1 GB:DB_XREF GI:34732788 GB:GENE:GENE 60plus39 LENGTH 607 SQ:AASEQ MSDEFKVLTPREHVILRPNMYVGSVAYEPHERFLFGKFQSVSYVPGLVKIIDEIIDNSVDEGIRTDFKFANKIDIRFDLLEGSVTVVDNGRGIPQSMVETPDGEMPKPVAAWTQTMAGSNFDDTNRVSMGMNGVGSSLTNFFSKKFIGETCDGKNFLTVTCSEGASNIDWETKPGKIKGTSVYFIPDEKHFEGRTIDQQIIDIISDRITALSVVFPQIKFTINGQIASMKFADYAKMFGDESLIVESDRFSIAICNSPEGFRQVSYVNGLNIKNGGSHIDYLVDGISEELMPAIKKKHKIEISKARVKECLTMVVVVRGMSNLRFDSQTKERLTNPAGEVKSHFDLDFKKLSKQIMNTDAILQPIIEAALARHLAAEKAAMTKAQKAAAKTNCAKHIKAGEWGRNDIETTLFLTEGESAIGYLLKVKDENLHGGYALRGKVMNTWGMKGSDVLKNNELSDICAITGLDLANPDDISQRKYKNIAIMTDADPDGQGSIYPCLLAFFARWPKLFDEGSVRFVKTPVVILNKGKNTKWFYTLTEFEKEKKDYKGWDLRYIKGLGSLREHEYSDVVNNPNYDIVDLGDDWEELFEMLLGDDAALRKEWMSQ GT:EXON 1|1-607:0| BL:SWS:NREP 2 BL:SWS:REP 1->469|TOPL_BPT4|e-136|59.9|466/516| BL:SWS:REP 476->607|TOPS_BPT4|4e-45|59.1|132/160| SEG 194->209|rtidqqiidiisdrit| SEG 367->395|eaalarhlaaekaamtkaqkaaaktncak| BL:PDB:NREP 2 BL:PDB:REP 9->362|1zxnA|1e-30|31.0|336/366| BL:PDB:REP 405->605|3fofD|4e-15|33.7|184/199| RP:PDB:NREP 2 RP:PDB:REP 37->149|1b1jA|2e-12|12.8|109/123| RP:PDB:REP 288->592|1dc1B|2e-35|7.9|290/311| RP:PFM:NREP 1 RP:PFM:REP 256->366|PF00204|6e-07|33.3|108/169|DNA_gyraseB| HM:PFM:NREP 4 HM:PFM:REP 248->382|PF00204|3.6e-31|32.8|131/173|DNA_gyraseB| HM:PFM:REP 45->187|PF02518|8.5e-15|27.2|103/111|HATPase_c| HM:PFM:REP 585->605|PF00986|0.00051|42.9|21/65|DNA_gyraseB_C| HM:PFM:REP 179->221|PF08469|0.00065|23.3|43/148|NPHI_C| GO:PFM:NREP 5 GO:PFM GO:0003677|"GO:DNA binding"|PF00204|IPR013506| GO:PFM GO:0003918|"GO:DNA topoisomerase (ATP-hydrolyzing) activity"|PF00204|IPR013506| GO:PFM GO:0005524|"GO:ATP binding"|PF00204|IPR013506| GO:PFM GO:0005694|"GO:chromosome"|PF00204|IPR013506| GO:PFM GO:0006265|"GO:DNA topological change"|PF00204|IPR013506| RP:SCP:NREP 2 RP:SCP:REP 2->225|1pvgA2|2e-25|27.6|221/239|d.122.1.2| RP:SCP:REP 294->592|1dc1A|1e-33|8.5|284/310|c.52.1.11| HM:SCP:REP 1->230|1pvgA2|4.2e-40|29.2|226/239|d.122.1.2|1/1|ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase| HM:SCP:REP 220->371|1pvgA1|5.2e-28|30.9|149/161|d.14.1.3|1/1|Ribosomal protein S5 domain 2-like| HM:SCP:REP 385->607|1bjtA_|1e-46|29.7|222/760|e.11.1.1|1/1|Type II DNA topoisomerase| OP:NHOMO 1733 OP:NHOMOORG 1084 OP:PATTERN -----------------------11111-111-----------1111111111--------111---- 1111211111111111112-12111311111122221111211111222222222122222221221111222222221111111111222212222-1222222222222222222222222221111111111111111111-111-111111111111111111111111111111111111111111122222222222222222222222222222222222222222222222222222222222222222222222222222212122222222222222222222222222222222222222222222222222111221111111212111121112221112211221111211111111111-21222----11-22211111111------------111111111-21-111--1---112111111111112221111111111111112--111-------221112122222211111221211111122222222222222222222223222222222222222122211221--111222211111-1212-12121111-111111111111111111211--111-111111111111111-11--111121111111122222222222222222221-221121-111122122212212222222-2212222222222222222222122222222222222222222222222222-222222222222111222222111121121222111222212221222222211121222211111111111111111111112222222222222221111111111111122112222222222222221211112-22222222222222222221111111111-12 11-1221152211121111111111111111111111111-111111111111111111111111111-111111111111-111111-12112111111121111113212223341222222222319I2-4262222212332222221131432213912351111443323222G2222242341333423221 ---11--------------1---------------111-2----------------------------------------------------------------------------------------------------------------------------------111-- STR:NPRED 606 STR:RPRED 99.8 SQ:SECSTR #HHHcccccHHHHHHHcHHHHHccccHHEEEEEEEEHHHHHHcHHHHHHHHHHHHHHHHHHHHTHHGTcccEEEEEEcTTTccEEEEEEcccHHHHHHHHHHHHHTccGGHTEEEEEEEEcccccEEEEEETTEEcccHHHHHHccccccccHHTTcccEEEEEEEcccccccTTTTcEEEEEEEEcTTTccTTTcccccHHHHHHHHHHHHHHcTTcEEEEEETTTTEEHHHHHHHHHTTcccccccEEEEEEEEcccccEEEEEETTEEcTTccHHHHHHHHHHHcGGGGTcccGGGccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHTcccGGGGGcGGGHHHHHHHTTccHHHHTTccHHHHHHHHHHHHHHTEEEcTTccEETTTTGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEETTcTTcccEEEcccccTTGGGGEEEEEETTEEEEEEEEEEETTTTEEEEEHEEEEcccccHGGGEEEEEEccccHHHHHHHHHHHHHHHHHHHHHHHHTTccccEEEEEEccccHHHHHHHHHHHHHTcccEEEETHHHHHHHHHHHTccccTHHHHHHHHHHH DISOP:02AL 1-2,167-173,382-391,607-608| PSIPRED cccccEEcccccHHHcccccEEEccccccEEEEEEccccccccccHHHHHHHHHHHHHHHHHHHcccccccEEEEEEEEEccEEEEEEccccccEEEEcccccccccEEEEEEEEEcccccccccEEEEccccHHHHHEEEEccEEEEEEEEccEEEEEEEEccEEcccEEEccccccEEEEEEEEcHHHHccccHHHHHHHHHHHHHHHHHHcccccEEEEEccEEEEEHHHHHHHcccccEEEEccccEEEEEEcccccEEEEEEccccccccccHHHHHHHHHHHHHHHHHHHHccccccHHHHHccEEEEEEEcccccccccccccccccccHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccHHHcEEEEEEccccHHHHHHccccccEEEEEccccEEEHHcccHHHHHccHHHHHHHHHHcccccccccHHHccccEEEEEEcccccccHHHHHHHHHHHHHHHHHHHccEEEEEEccEEEEEccccEEEEccHHHHHHHHHcccccEEEEEEccccccHHHHHHHHHcccEEEEccccHHHHHHHHHHcccHHHHHHHHcc //