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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : acoL
DDBJ      :acoL         acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase)
Swiss-Prot:DLDH3_BACSU  RecName: Full=Dihydrolipoyl dehydrogenase;         EC=1.8.1.4;AltName: Full=Dihydrolipoamide dehydrogenase;AltName: Full=E3 component of acetoin cleaving system;

Homologs  Archaea  61/68 : Bacteria  866/915 : Eukaryota  194/199 : Viruses  0/175   --->[See Alignment]
c.3.1d.87.1
:458 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   31->457 1lpfA PDBj 4e-72 35.8 %
:RPS:PDB   24->457 1dxlA PDBj 2e-67 33.3 %
:RPS:SCOP  32->149 1aogA1  c.3.1.5 * 6e-15 22.6 %
:RPS:SCOP  125->335 1gv4A1  c.3.1.5 * 2e-28 14.5 %
:RPS:SCOP  337->457 1bhyA3  d.87.1.1 * 5e-31 27.3 %
:HMM:SCOP  1->314 1d5tA1 c.3.1.3 * 1.8e-59 33.9 %
:HMM:SCOP  335->457 1aogA3 d.87.1.1 * 5.8e-32 39.0 %
:RPS:PFM   26->310 PF07992 * Pyr_redox_2 3e-18 36.5 %
:RPS:PFM   339->448 PF02852 * Pyr_redox_dim 3e-21 45.9 %
:HMM:PFM   3->309 PF07992 * Pyr_redox_2 9.2e-52 42.3 194/202  
:HMM:PFM   339->447 PF02852 * Pyr_redox_dim 2.6e-35 37.6 109/110  
:BLT:SWISS 24->458 DLDH3_BACSU 0.0 100.0 %
:PROS 35->45|PS00076|PYRIDINE_REDOX_1
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB12638.1 GT:GENE acoL GT:PRODUCT acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase) GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 882266..883642 GB:FROM 882266 GB:TO 883642 GB:DIRECTION + GB:GENE acoL GB:PRODUCT acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase) GB:FUNCTION 16.11: Scavenge (Catabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type e: enzyme GB:PROTEIN_ID CAB12638.1 GB:DB_XREF GOA:O34324 HSSP:1LPF InterPro:IPR001327 SubtiList:BG12561 UniProtKB/Swiss-Prot:O34324 GB:GENE:GENE acoL LENGTH 458 SQ:AASEQ MTLAIIGGGPAGYAAAVSAAQQGRNVLLIDKGKLGGTCLNEGCIPTKSLLESANVLDKIKHADSFGIELPAGAISVDWSKMQSRKQQVVSQLVQGVQYLMKKNQIQVVKGTASFLSERKLLIEGENGKEIREADQVLIASGSEPIELPFAPFDGEWILDSKDALSLSEIPSSLVIVGGGVIGCEYAGLFARLGSQVTIIETADRLIPAEDEDIARLFQEKLEEDGVEVHTSSRLGRVDQTAKTAIWKSGQREFKTKADYVLVAIGRKPRLDGLQLEQAGVDFSPKGIPVNGHMQTNVPHIYACGDAIGGIQLAHAAFHEGIIAASHASGRDVKINEKHVPRCIYTSPEIACIGMTERQARSIYGDVKIGEFSFSANGKALIKQQAEGKVKIMAEPEFGEIVGVSMIGPDVTELIGQAAAIMNGEMTADMAEHFIAAHPTLSETLHEALLSTIGLAVHA GT:EXON 1|1-458:0| SW:ID DLDH3_BACSU SW:DE RecName: Full=Dihydrolipoyl dehydrogenase; EC=1.8.1.4;AltName: Full=Dihydrolipoamide dehydrogenase;AltName: Full=E3 component of acetoin cleaving system; SW:GN Name=acoL; Synonyms=yfjH; OrderedLocusNames=BSU08090; SW:KW Acetoin catabolism; Complete proteome; Cytoplasm; Disulfide bond; FAD;Flavoprotein; Glycolysis; NAD; Oxidoreductase; Redox-active center. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 24->458|DLDH3_BACSU|0.0|100.0|435/458| GO:SWS:NREP 5 GO:SWS GO:0045150|"GO:acetoin catabolic process"|Acetoin catabolism| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006096|"GO:glycolysis"|Glycolysis| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| PROS 35->45|PS00076|PYRIDINE_REDOX_1|PDOC00073| SEG 4->23|aiigggpagyaaavsaaqqg| SEG 86->97|qqvvsqlvqgvq| SEG 174->182|vivgggvig| BL:PDB:NREP 1 BL:PDB:REP 31->457|1lpfA|4e-72|35.8|425/472| RP:PDB:NREP 1 RP:PDB:REP 24->457|1dxlA|2e-67|33.3|433/467| RP:PFM:NREP 2 RP:PFM:REP 26->310|PF07992|3e-18|36.5|241/275|Pyr_redox_2| RP:PFM:REP 339->448|PF02852|3e-21|45.9|109/110|Pyr_redox_dim| HM:PFM:NREP 2 HM:PFM:REP 3->309|PF07992|9.2e-52|42.3|194/202|Pyr_redox_2| HM:PFM:REP 339->447|PF02852|2.6e-35|37.6|109/110|Pyr_redox_dim| GO:PFM:NREP 5 GO:PFM GO:0005737|"GO:cytoplasm"|PF02852|IPR004099| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF02852|IPR004099| GO:PFM GO:0045454|"GO:cell redox homeostasis"|PF02852|IPR004099| GO:PFM GO:0050660|"GO:FAD binding"|PF02852|IPR004099| GO:PFM GO:0055114|"GO:oxidation reduction"|PF02852|IPR004099| RP:SCP:NREP 3 RP:SCP:REP 32->149|1aogA1|6e-15|22.6|118/238|c.3.1.5| RP:SCP:REP 125->335|1gv4A1|2e-28|14.5|207/224|c.3.1.5| RP:SCP:REP 337->457|1bhyA3|5e-31|27.3|121/128|d.87.1.1| HM:SCP:REP 1->314|1d5tA1|1.8e-59|33.9|307/0|c.3.1.3|1/1|FAD/NAD(P)-binding domain| HM:SCP:REP 335->457|1aogA3|5.8e-32|39.0|123/130|d.87.1.1|1/1|FAD/NAD-linked reductases, dimerisation (C-terminal) domain| OP:NHOMO 3992 OP:NHOMOORG 1121 OP:PATTERN 221-115344445455233-31134222145112211-1111122-2111332222221113341--- 4445743344533394555-7611865455535444378634455545555256A44433449464555321111222--113231114442-32212222227333232111111111111113121222112122331211132444444312332222232224547422222222222232244111153444444443445444353353444242326654444454333333333333333385644231541322255333325464243453344444433333323333322332222222224333333333224--33322321211433--1122--13-11153142234135543112216533433333356343343333344454444445-4454654767534554668777773A55555444445653333333353324343223222222211222222222222222221535724545867776864444663555553456647583245444366545452365311133333333357353223412432333222-324245331333344-3111-------------------112564447754535622222242422332223231-1764511111143434334445455544-4444455444454343444444333334444454444364445433333343145555555555511331111144542475522222222222222254445345543356675555455564433444445344344554444464545433443422222222231443333--------1-322211-1-22111222121122---2211131313541 4411225-C55-2222222132323222222222212222222221333335482223222222222222222233323322222222-53222222222222425-38674734465444554CA1E2N*9-B6J3333A4565345545458486566AE34321533755754554*44445665A2849A88679 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 435 STR:RPRED 95.0 SQ:SECSTR #######################cEEEEEccccccccHHHHcHHHHHHHHHHHHHHHHHHHTHHHHTccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHHTcEEEEccEEEEETTEEEEcccccccEEEccEEEEcccEEEcccTTcccccccEEcHHHHTTccccccEEEEccccHHHHHHHHHHHHHTcEEEEEcccccccTTccHHHHHHHHHHHHHccccEEccEEEEEEEcccccEEEEcccccEEEEEcEEEccccEEEccTTcccTTTTcccccccccccTTcccccTTEEEccTTccccccHHHHHHHHHHHHHHHTTccccccTTcccEEEccccEEEEEEccHHHHHHTTccEEEEEEEGGGcHHHHHHcccccEEEEEEETTTccEEEEEEEETTHHHHHHHHHHHHHTTccHHHHHTcccccccTTHHHHHHHHHHHcccccc PSIPRED cEEEEEcccHHHHHHHHHHHHcccEEEEEEcccccEEEEEEccccHHHHHHHHHHHHHHHHHHHcccEEEccccEEcHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEEEEccccEEEEEEccccEEEEEEEEEEEcccccccccccccccccEEEHHHHHcHHHcccEEEEEcccHHHHHHHHHHHHcccEEEEEEccccccccccHHHHHHHHHHHHHcccEEEcccEEEEEEEcccEEEEEEccccEEEEEcEEEEEcccEEEcccccHHHccEEEcccEEEEccccccccccEEEEEEccccccccHHHHHHHHHHHHHHcccccccccccccEEEEEcccEEEEEccHHHHHHccccEEEEEEEccccccEEcccccEEEEEEEEEcccccEEEEEEEEccHHHHHHHHHHHHHccccHHHHHcccccccccHHHHHHHHHHHccccccc //