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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : aprX
DDBJ      :aprX         alkaline serine protease
Swiss-Prot:             

Homologs  Archaea  20/68 : Bacteria  259/915 : Eukaryota  170/199 : Viruses  0/175   --->[See Alignment]
c.41.1
:442 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   132->436 1y4dE PDBj 7e-33 41.7 %
:RPS:PDB   142->439 3cnqS PDBj 2e-49 39.7 %
:RPS:SCOP  142->436 1a2qA  c.41.1.1 * 7e-53 43.8 %
:HMM:SCOP  56->439 1r6vA_ c.41.1.1 * 2e-84 36.0 %
:RPS:PFM   145->410 PF00082 * Peptidase_S8 6e-41 48.8 %
:HMM:PFM   143->424 PF00082 * Peptidase_S8 1.7e-59 44.0 243/307  
:HMM:PFM   64->123 PF05922 * Inhibitor_I9 0.00095 22.0 50/87  
:BLT:SWISS 111->435 ELYA_BACHD 3e-34 38.3 %
:PROS 151->161|PS00136|SUBTILASE_ASP
:PROS 187->197|PS00137|SUBTILASE_HIS
:PROS 382->392|PS00138|SUBTILASE_SER
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB13610.1 GT:GENE aprX GT:PRODUCT alkaline serine protease GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION complement(1861384..1862712) GB:FROM 1861384 GB:TO 1862712 GB:DIRECTION - GB:GENE aprX GB:PRODUCT alkaline serine protease GB:FUNCTION 16.6: Maintain 16.11: Scavenge (Catabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10589719, 16267290, 17884659; Product type e: enzyme GB:PROTEIN_ID CAB13610.1 GB:DB_XREF GOA:O31788 HSSP:1MPT InterPro:IPR000209 SubtiList:BG12567 UniProtKB/TrEMBL:O31788 GB:GENE:GENE aprX LENGTH 442 SQ:AASEQ MFGYSMVQMVRANAHKLDWPLRETVLQLYKPFKWTPCFLHKFFETKLQNRKKMSVIIEFEEGCHETGFQMAGEVLQKEKRSKLKSRFNKINCCSAEVTPSALHSLLSECSNIRKVYLNREVKALLDTATEASHAKEVVRNGQTLTGKGVTVAVVDTGIYPHPDLEGRIIGFADMVNQKTEPYDDNGHGTHCAGDVASSGASSSGQYRGPAPEANLIGVKVLNKQGSGTLADIIEGVEWCIQYNEDNPDEPIDIMSMSLGGDALRYDHEQEDPLVRAVEEAWSAGIVVCVAAGNSGPDSQTIASPGVSEKVITVGALDDNNTASSDDDTVASFSSRGPTVYGKEKPDILAPGVNIISLRSPNSYIDKLQKSSRVGSQYFTMSGTSMATPICAGIAALILQQNPDLTPDEVKELLKNGTDKWKDEDPNIYGAGAVNAENSVPGQ GT:EXON 1|1-442:0| BL:SWS:NREP 1 BL:SWS:REP 111->435|ELYA_BACHD|3e-34|38.3|277/361| PROS 151->161|PS00136|SUBTILASE_ASP|PDOC00125| PROS 187->197|PS00137|SUBTILASE_HIS|PDOC00125| PROS 382->392|PS00138|SUBTILASE_SER|PDOC00125| SEG 196->204|assgasssg| SEG 315->328|alddnntassdddt| BL:PDB:NREP 1 BL:PDB:REP 132->436|1y4dE|7e-33|41.7|259/276| RP:PDB:NREP 1 RP:PDB:REP 142->439|3cnqS|2e-49|39.7|242/264| RP:PFM:NREP 1 RP:PFM:REP 145->410|PF00082|6e-41|48.8|242/285|Peptidase_S8| HM:PFM:NREP 2 HM:PFM:REP 143->424|PF00082|1.7e-59|44.0|243/307|Peptidase_S8| HM:PFM:REP 64->123|PF05922|0.00095|22.0|50/87|Inhibitor_I9| GO:PFM:NREP 2 GO:PFM GO:0004252|"GO:serine-type endopeptidase activity"|PF00082|IPR000209| GO:PFM GO:0006508|"GO:proteolysis"|PF00082|IPR000209| RP:SCP:NREP 1 RP:SCP:REP 142->436|1a2qA|7e-53|43.8|249/275|c.41.1.1| HM:SCP:REP 56->439|1r6vA_|2e-84|36.0|353/0|c.41.1.1|1/1|Subtilisin-like| OP:NHOMO 1292 OP:NHOMOORG 449 OP:PATTERN 111-------------1-11-1-2------13--------------1812-2---3-234------1- ------1-111---1---------1------1------3121-1-3-2-1-1--421---6911B3397C------------21-1--111--------1-122-11121---------------1--1---1-3134456-1-81243-11111----11-211-16343----1--1----C32-1--1-263333344436435445988774633233733------931--------------------1--------1----11-------------------------------------------1---------311231111111111-122111111---4111---22124312212-2--1-1------------1-1-------------------1----2-------------1-------1-------------------------------------------------------------------1----1-1111---12222-211-1-1------1--------------------------1111--4---------1----122-413----1-53-1-------1-------------------1--21-4211-2-11141-322-11---13--3-----------------------------------------------------1---------------------------1--------------9---------1-1-----------------11111------1------1---------------------1-11111121111--22123-----------------------------------------------------2-121-------- ---1451-1---135556323323223332222987886887812211978A8A5573312283322213333333323324444422-1-154-11-111218BA1193D3111311--1-2-54-2-4B2142311-11-21211-1-3-1311223--33911-111---11-122G221432BBW5HDB559581 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 381 STR:RPRED 86.2 SQ:SECSTR #####################################################EEEEEEcTT#######TccHHHHHHTTcEEEEEccccccEEEEccccccccG#GGTTTEEEEETcccccccccccccHHHHHHHTTccTTcccTTcEEEEEEccccTTcccccccEEEEccTTcccTTcccccHHHHHHHHHHccccccccHHHHHcTTcEEEEEEcccTTccccHHHHHHHHHHHHHTTHHHHcccccEEEEccccccEcccHcccHHHHHHHHHHHHTTcEEEEEcccccccccccccTTTcTTcEEEEEEcTTcccTEEEEcccEEcTTccccTTccTccEEEEcccEEEEETTTEEEcGGcEEEETTTEEEEEccHHHHHHHHHHHHHHHHHHcTTccHHHHHHHHHHTccccccccHHHHTTccccHHHHTTTE DISOP:02AL 44-54, 63-81| PSIPRED cccHHHHHHHHHccccccHHHHHHEEEEEEHHHccEEEEHHHHHHHHHcccccEEEEEEcccccHHHHHHHHHHHHHHHccEEEEEEccEEEEEEEEcHHHHHHHHHccccEEEEEEccEEEEEEccccccccccHHHHcccccccccEEEEEEEccccccHHHcccEEEEEcEEEcccccccccccHHHHHHHHHHcccccccEEEEcccccEEEEEEEEcccccccHHHHHHHHHHHHHHHHHHccccEEEEEEccccccccccccccHHHHHHHHHHHHcccEEEEEcccccccccccccccccccEEEEEEEccccccccccccccccccccccccccccccEEEcccccEEccccccccccccccccccccEEEEcccHHHHHHHHHHHHHHHHHcccccHHHHHHHHHHccccccccccccEEEEEEEHHHccccc //