[GTOP] [HELP] [ORGANISMS] [SEARCH] [SUMMARY]
Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : dnaE
DDBJ      :dnaE         DNA polymerase III (alpha subunit)
Swiss-Prot:DPO3A_BACSU  RecName: Full=DNA polymerase III subunit alpha;         EC=2.7.7.7;

Homologs  Archaea  0/68 : Bacteria  908/915 : Eukaryota  3/199 : Viruses  3/175   --->[See Alignment]
a.4.6b.29.1b.40.4b.42.4c.6.3d.58.1
:1115 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->989 3e0dA PDBj 0.0 45.4 %
:RPS:PDB   1->1082 3e0dA PDBj 0.0 41.3 %
:RPS:SCOP  86->152 1q16B  d.58.1.5 * 3e-11 6.0 %
:RPS:SCOP  264->403 1r8nA  b.42.4.1 * 2e-35 19.1 %
:RPS:SCOP  380->487 1fc3A  a.4.6.3 * 1e-21 7.5 %
:RPS:SCOP  656->836 1kitA2  b.29.1.8 * 4e-48 9.1 %
:RPS:SCOP  915->1023 1asyA1  b.40.4.1 * 1e-12 15.9 %
:HMM:SCOP  2->254 1m65A_ c.6.3.1 * 1.7e-17 25.2 %
:RPS:PFM   6->132 PF02811 * PHP 3e-09 38.0 %
:RPS:PFM   281->699 PF07733 * DNA_pol3_alpha e-150 61.3 %
:RPS:PFM   967->1030 PF01336 * tRNA_anti 7e-07 31.2 %
:HMM:PFM   281->703 PF07733 * DNA_pol3_alpha 7.4e-179 57.2 418/422  
:HMM:PFM   4->166 PF02811 * PHP 9.2e-30 28.9 159/175  
:HMM:PFM   963->1030 PF01336 * tRNA_anti 1.3e-10 29.4 68/76  
:BLT:SWISS 1->1115 DPO3A_BACSU 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB14883.1 GT:GENE dnaE GT:PRODUCT DNA polymerase III (alpha subunit) GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION complement(2991269..2994616) GB:FROM 2991269 GB:TO 2994616 GB:DIRECTION - GB:GENE dnaE GB:PRODUCT DNA polymerase III (alpha subunit) GB:FUNCTION 16.9: Replicate GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14593098, 9799485, 9822387, 10354411; Product type e: enzyme GB:PROTEIN_ID CAB14883.1 GB:DB_XREF GOA:O34623 InterPro:IPR004805 SubtiList:BG12583 UniProtKB/Swiss-Prot:O34623 GB:GENE:GENE dnaE LENGTH 1115 SQ:AASEQ MSFVHLQVHSGYSLLNSAAAVEELVSEADRLGYASLALTDDHVMYGAIQFYKACKARGINPIIGLTASVFTDDSELEAYPLVLLAKSNTGYQNLLKISSVLQSKSKGGLKPKWLHSYREGIIAITPGEKGYIETLLEGGLFEQAAQASLEFQSIFGKGAFYFSYQPFKGNQVLSEQILKLSEETGIPVTATGDVHYIRKEDKAAYRCLKAIKAGEKLTDAPAEDLPDLDLKPLEEMQNIYREHPEALQASVEIAEQCRVDVSLGQTRLPSFPTPDGTSADDYLTDICMEGLRSRFGKPDERYLRRLQYELDVIKRMKFSDYFLIVWDFMKHAHEKGIVTGPGRGSAAGSLVAYVLYITDVDPIKHHLLFERFLNPERVSMPDIDIDFPDTRRDEVIQYVQQKYGAMHVAQIITFGTLAAKAALRDVGRVFGVSPKEADQLAKLIPSRPGMTLDEARQQSPQLDKRLRESSLLQQVYSIARKIEGLPRHASTHAAGVVLSEEPLTDVVPLQEGHEGIYLTQYAMDHLEDLGLLKMDFLGLRNLTLIESITSMIEKEENIKIDLSSISYSDDKTFSLLSKGDTTGIFQLESAGMRSVLKRLKPSGLEDIVAVNALYRPGPMENIPLFIDRKHGRAPVHYPHEDLRSILEDTYGVIVYQEQIMMIASRMAGFSLGEADLLRRAVSKKKKEILDRERSHFVEGCLKKEYSVDTANEVYDLIVKFANYGFNRSHAVAYSMIGCQLAYLKAHYPLYFMCGLLTSVIGNEDKISQYLYEAKGSGIRILPPSVNKSSFPFTVENGSVRYSLRAIKSVGVSAVKDIYKARKEKPFEDLFDFCFRVPSKSVNRKMLEALIFSGAMDEFGQNRATLLASIDVALEHAELFAADDDQMGLFLDESFSIKPKYVETEELPLVDLLAFEKETLGIYFSNHPLSAFRKQLTAQGAVSILQAQRAVKRQLSLGVLLSKIKTIRTKTGQNMAFLTLSDETGEMEAVVFPEQFRQLSPVLREGALLFTAGKCEVRQDKIQFIMSRAELLEDMDAEKAPSVYIKIESSQHSQEILAKIKRILLEHKGETGVYLYYERQKQTIKLPESFHINADHQVLYRLKELLGQKNVVLKQW GT:EXON 1|1-1115:0| SW:ID DPO3A_BACSU SW:DE RecName: Full=DNA polymerase III subunit alpha; EC=2.7.7.7; SW:GN Name=dnaE; OrderedLocusNames=BSU29230; SW:KW Complete proteome; Cytoplasm; DNA replication;DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1115|DPO3A_BACSU|0.0|100.0|1115/1115| GO:SWS:NREP 5 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006260|"GO:DNA replication"|DNA replication| GO:SWS GO:0003887|"GO:DNA-directed DNA polymerase activity"|DNA-directed DNA polymerase| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| SEG 17->28|saaaveelvsea| SEG 219->235|dapaedlpdldlkplee| BL:PDB:NREP 1 BL:PDB:REP 1->989|3e0dA|0.0|45.4|955/1148| RP:PDB:NREP 1 RP:PDB:REP 1->1082|3e0dA|0.0|41.3|1046/1148| RP:PFM:NREP 3 RP:PFM:REP 6->132|PF02811|3e-09|38.0|121/177|PHP| RP:PFM:REP 281->699|PF07733|e-150|61.3|419/428|DNA_pol3_alpha| RP:PFM:REP 967->1030|PF01336|7e-07|31.2|64/74|tRNA_anti| HM:PFM:NREP 3 HM:PFM:REP 281->703|PF07733|7.4e-179|57.2|418/422|DNA_pol3_alpha| HM:PFM:REP 4->166|PF02811|9.2e-30|28.9|159/175|PHP| HM:PFM:REP 963->1030|PF01336|1.3e-10|29.4|68/76|tRNA_anti| GO:PFM:NREP 5 GO:PFM GO:0003824|"GO:catalytic activity"|PF02811|IPR004013| GO:PFM GO:0005737|"GO:cytoplasm"|PF07733|IPR011708| GO:PFM GO:0006260|"GO:DNA replication"|PF07733|IPR011708| GO:PFM GO:0008408|"GO:3'-5' exonuclease activity"|PF07733|IPR011708| GO:PFM GO:0003676|"GO:nucleic acid binding"|PF01336|IPR004365| RP:SCP:NREP 5 RP:SCP:REP 86->152|1q16B|3e-11|6.0|67/509|d.58.1.5| RP:SCP:REP 264->403|1r8nA|2e-35|19.1|131/185|b.42.4.1| RP:SCP:REP 380->487|1fc3A|1e-21|7.5|106/119|a.4.6.3| RP:SCP:REP 656->836|1kitA2|4e-48|9.1|175/197|b.29.1.8| RP:SCP:REP 915->1023|1asyA1|1e-12|15.9|107/137|b.40.4.1| HM:SCP:REP 2->254|1m65A_|1.7e-17|25.2|230/0|c.6.3.1|1/1|PHP domain-like| OP:NHOMO 1266 OP:NHOMOORG 914 OP:PATTERN -------------------------------------------------------------------- 3222222222222222222-22112222222222222222222232222211242221112222113232111112111111211111111111111112131224141311111111111111111111-111111111111112222122211221111112221222211111111111121111111211111111111111121111112111111111111111112111111111111111212211111111111111111211111111111111111111111111111111111111111111111111111111211211121111111111-2111112112111111112211111112212322211111222223222222222122221213122223222322-3442332333232322232221222221111111124221211111111111111111111111111111111222212221242532232222333223222224222221122223422222231222211111111111111222222131111111111121211112122222212111111111111111111111111122111222121112111111111112112111111122111111111111111111111111-11111111111111111111111111111111111111211111111111111112112222111111111111111121211111111111-11111111111111111222222222222222221111111111111111111222222222222222111111111111111111111111111111-11111111111111111111111122222121 -------------------------------------------------------------------------------------------------------------------------------------------------------------------1---------1--------------3---------- --------------1-----------------------------------------------------------------1---------------------------------------------1------------------------------------------------ STR:NPRED 1077 STR:RPRED 96.6 SQ:SECSTR ccccccccccTTcTTTccccHHHHHHHHHHHcccEEEEEEETccTTHHHHHHHHHTTTcEEEEEEEEEETTccccccEEEEEEEEccHHHHHHHHHHHHHHHHTcccEEcHHHHHHTcTTEEEEcccTTcHHHHHHHTTcHHHHHHHHHHHHHHHGTGGEEEEEcccHHHHHHHHHHHHHHHHTTccEEEccccccccGGGHHHHHHHHHHHTTccccccccccccccccccHHHHHHHccHHHHHHHHHHHHHHTcccccccTTcccccccccccccHHHHHHHHHHHHHHHHcTTTHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHHHHHHTTTcccccccGGGGGcHHHHHTTcccccTTTTTccHHHHccTTcccccccEEEEETTTHHHHHHHHHHHHcTTTEEEEEEEccccHHHHHHHHHHHTTccHHHHHHHHTTccccccccTTTTTcccTTTTTHHHHcHHHHHHHHHHHHcTTccccEEEcccEEEEccccGGGTccEEEcTTccEEEEEEHHHHHTTTcEEEEEEEEHHHHHHHHHHHHHHHHHcccccGGGccTTcHHHHHHHHTTccTTcTTcccHHHHHHHHHHccccHHHHHHHHHHccTTGGGHHHHHHHHHTTccccccTHHHHHHHHGGGTTccccHHHHHHHHHHHccccHHHHHHHHHHHHHTcTTTHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHTTccccHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHTTTcHHHHHHHHHHHHTTcccEEcccTTTcccccEEETTEEEcccTTcccccHHHHHHHHHHHHHcccccHHHHHHHccTTTccHHHHHHHHHHTTTGGGcccHHHHHHHHHHHHHHHHHHHHHHTccccccccc###cccccccccccHHHHHHHHHHHHcccccccGGGTcHHHHccccGGGHHHHHcccccc#EEEEEcccccEEEEEEEEccccEEEEETTEEEEEccTTHHHHHHHHHccTcEEEEEEEEEEEccEEEEEEccHHHHTcccccTccccEEEEEcccc#cTTTccHHHHHHHTcEEEEEEEEEEEccccE################################# DISOP:02AL 879-899| PSIPRED ccEEEEEcccccHHHHHcccHHHHHHHHHHccccEEEEEcccHHHHHHHHHHHHHHccccEEEEEEEEEEcccccccccEEEEEEccHHHHHHHHHHHHHHHHcccccccHHHHHHHHccEEEEEccccccHHHHHHcccHHHHHHHHHHHHHHccccEEEEEEcccccHHHHHHHHHHHHHHHcccEEEccccccccHHHHHHHHHHHHHHccccccccccccccccccccHHHHHHHHHHHHHHHHHHHHHHHHHccHHHccccccccccccccccHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHcccEEcccccHHHHHHHHHHHHcccccccccccccccccccccccccEEEcccccccHHHHHHHHHHHcccccEEEEEEEccHHHHHHHHHHHHHHcccHHHHHHHHHHccccccccHHHHHHHcccHHHHHHccHHHHHHHHHHHHHcccccccccccEEEEEcccccEEEcccEEcccccEEEEccHHHHHHcccEEEEEEccccHHHHHHHHHHHHHHccccccHHHcccccHHHHHHHHcccEEEEcccccHHHHHHHHHcccccHHHHHHHHHccccccHHHHHHHHHccccccccccccHHHHHHHHHHccEEEEHHHHHHHHHHHccccHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHcccccHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHcccccHHHHHHHHHHHHHcccEEccccccccccEEEEEccEEEccHHHcccccHHHHHHHHHHHcccccccHHHHHHHcccccccHHHHHHHHHccccccccHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccHHHcccccccccccHHHHHHHHHHHHcEEEcccHHHHHHHHHHHHccccHHHHHcccccEEEEEEEEEEEEEEccccccEEEEEEEEccccEEEEEEHHHHHHHHHHHHccccEEEEEEEEEEEccEEEEEEEEcccHHHHHHHccccEEEEEEcccccHHHHHHHHHHHHHcccccEEEEEEEcccEEEEEcccEEEcccHHHHHHHHHHcccccEEEEEc //