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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : gltA
DDBJ      :gltA         glutamate synthase (large subunit)
Swiss-Prot:GLTA_BACSU   RecName: Full=Glutamate synthase [NADPH] large chain;         EC=1.4.1.13;AltName: Full=NADPH-GOGAT;

Homologs  Archaea  48/68 : Bacteria  659/915 : Eukaryota  133/199 : Viruses  0/175   --->[See Alignment]
b.80.4c.1.4d.153.1
:1520 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   22->1482 2vdcA PDBj 0.0 46.1 %
:RPS:PDB   22->1382 1ea0A PDBj e-160 44.6 %
:RPS:SCOP  22->440 1ea0A3  d.153.1.1 * 4e-84 39.4 %
:RPS:SCOP  438->1204 1ea0A2  c.1.4.1 * 0.0 49.7 %
:RPS:SCOP  1215->1478 1ea0A1  b.80.4.1 * 1e-95 43.1 %
:HMM:SCOP  22->442 1llwA3 d.153.1.1 * 7.4e-195 52.0 %
:HMM:SCOP  437->1207 1ea0A2 c.1.4.1 * 4.7e-268 48.2 %
:HMM:SCOP  1213->1484 1ea0A1 b.80.4.1 * 2.7e-99 50.7 %
:RPS:PFM   196->387 PF00310 * GATase_2 1e-50 59.9 %
:RPS:PFM   461->741 PF04898 * Glu_syn_central 4e-98 60.1 %
:RPS:PFM   832->1167 PF01645 * Glu_synthase e-130 68.0 %
:RPS:PFM   1248->1428 PF01493 * GXGXG 3e-58 57.2 %
:HMM:PFM   799->1167 PF01645 * Glu_synthase 5.5e-166 62.1 364/368  
:HMM:PFM   22->387 PF00310 * GATase_2 1.1e-148 53.2 359/362  
:HMM:PFM   462->741 PF04898 * Glu_syn_central 9e-122 57.5 280/288  
:HMM:PFM   1244->1438 PF01493 * GXGXG 4.8e-69 51.8 195/202  
:BLT:SWISS 1->1520 GLTA_BACSU 0.0 100.0 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB13728.2 GT:GENE gltA GT:PRODUCT glutamate synthase (large subunit) GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION complement(2010070..2014632) GB:FROM 2010070 GB:TO 2014632 GB:DIRECTION - GB:GENE gltA GB:PRODUCT glutamate synthase (large subunit) GB:FUNCTION 16.2: Construct biomass (Anabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14570271, 39113, 6769440, 6774712, 7559359; Product type e: enzyme GB:PROTEIN_ID CAB13728.2 GB:DB_XREF GOA:P39812 HSSP:1LM1 InterPro:IPR002932 SubtiList:BG10811 UniProtKB/Swiss-Prot:P39812 GB:GENE:GENE gltA LENGTH 1520 SQ:AASEQ MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHDIVKQGLKMLCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKNINLPEKERYGVGMVFFSQKEDERKKIEKQINALIEQEGQVVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGASSDLKDNLSFERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSAFALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNKILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHSSLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVLYKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDPESREEEQFSDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQSLFNYFKQLFAQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSNEQFYALKTIVHPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNERLTPIPPLLAVSALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLAYATYKQEIDEGRLDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFSGTASQLGGIDLQTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWACRRNDYNLFKQYTKAADEERIGFLRNLFAFDGNRKPLKLEEVESAESIVKRFKTGAMSFGSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDRRSAIKQIASGRFGVKSHYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTSIKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAPLVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGFKTFDEMIGRTDVLHASERAKEHWKASQLDLSTLLYQPEGVRTFQSPQNHKIDQSLDITTILPAVQEAIESGKEADISIEINNTNRVAGTITGSEISKRYGEEGLPEDTIKLHFTGSAGQSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSSEGFNSASDDNVIIGNVAFYGATSGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGDVGKNFAAGMSGGIAYVLTEDVKAFKRKCNLEMILFESLEDEKEIQQIKAMLERHTAYTNSQKAEDLLDQWEDSVKKFVKVIPKNYKQMLASIEEQKAAGLSDEEAIMFAFEANTKPKQNTAASGQKQAVVQ GT:EXON 1|1-1520:0| SW:ID GLTA_BACSU SW:DE RecName: Full=Glutamate synthase [NADPH] large chain; EC=1.4.1.13;AltName: Full=NADPH-GOGAT; SW:GN Name=gltA; OrderedLocusNames=BSU18450; SW:KW 3Fe-4S; Amino-acid biosynthesis; Complete proteome; FAD; Flavoprotein;FMN; Glutamate biosynthesis; Glutamine amidotransferase; Iron;Iron-sulfur; Metal-binding; NADP; Oxidoreductase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1520|GLTA_BACSU|0.0|100.0|1520/1520| GO:SWS:NREP 8 GO:SWS GO:0051538|"GO:3 iron, 4 sulfur cluster binding"|3Fe-4S| GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0006537|"GO:glutamate biosynthetic process"|Glutamate biosynthesis| GO:SWS GO:0006541|"GO:glutamine metabolic process"|Glutamine amidotransferase| GO:SWS GO:0051536|"GO:iron-sulfur cluster binding"|Iron-sulfur| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| GO:SWS GO:0016491|"GO:oxidoreductase activity"|Oxidoreductase| GO:SWS GO:0055114|"GO:oxidation reduction"|Oxidoreductase| BL:PDB:NREP 1 BL:PDB:REP 22->1482|2vdcA|0.0|46.1|1446/1472| RP:PDB:NREP 1 RP:PDB:REP 22->1382|1ea0A|e-160|44.6|1340/1452| RP:PFM:NREP 4 RP:PFM:REP 196->387|PF00310|1e-50|59.9|167/175|GATase_2| RP:PFM:REP 461->741|PF04898|4e-98|60.1|281/288|Glu_syn_central| RP:PFM:REP 832->1167|PF01645|e-130|68.0|331/342|Glu_synthase| RP:PFM:REP 1248->1428|PF01493|3e-58|57.2|180/195|GXGXG| HM:PFM:NREP 4 HM:PFM:REP 799->1167|PF01645|5.5e-166|62.1|364/368|Glu_synthase| HM:PFM:REP 22->387|PF00310|1.1e-148|53.2|359/362|GATase_2| HM:PFM:REP 462->741|PF04898|9e-122|57.5|280/288|Glu_syn_central| HM:PFM:REP 1244->1438|PF01493|4.8e-69|51.8|195/202|GXGXG| GO:PFM:NREP 9 GO:PFM GO:0008152|"GO:metabolic process"|PF00310|IPR000583| GO:PFM GO:0006807|"GO:nitrogen compound metabolic process"|PF04898|IPR006982| GO:PFM GO:0015930|"GO:glutamate synthase activity"|PF04898|IPR006982| GO:PFM GO:0055114|"GO:oxidation reduction"|PF04898|IPR006982| GO:PFM GO:0006537|"GO:glutamate biosynthetic process"|PF01645|IPR002932| GO:PFM GO:0015930|"GO:glutamate synthase activity"|PF01645|IPR002932| GO:PFM GO:0008152|"GO:metabolic process"|PF01493|IPR002489| GO:PFM GO:0016491|"GO:oxidoreductase activity"|PF01493|IPR002489| GO:PFM GO:0055114|"GO:oxidation reduction"|PF01493|IPR002489| RP:SCP:NREP 3 RP:SCP:REP 22->440|1ea0A3|4e-84|39.4|416/419|d.153.1.1| RP:SCP:REP 438->1204|1ea0A2|0.0|49.7|753/763|c.1.4.1| RP:SCP:REP 1215->1478|1ea0A1|1e-95|43.1|262/270|b.80.4.1| HM:SCP:REP 22->442|1llwA3|7.4e-195|52.0|417/422|d.153.1.1|1/1|N-terminal nucleophile aminohydrolases (Ntn hydrolases)| HM:SCP:REP 437->1207|1ea0A2|4.7e-268|48.2|765/0|c.1.4.1|1/1|FMN-linked oxidoreductases| HM:SCP:REP 1213->1484|1ea0A1|2.7e-99|50.7|270/0|b.80.4.1|1/1|Alpha subunit of glutamate synthase, C-terminal domain| OP:NHOMO 1290 OP:NHOMOORG 840 OP:PATTERN ---1--1111111111121111111--111112131112111112-21111111-2-----1------ 11113--111111121111-13112411111234442487122211-11111121222--112111231211111111----111111--1111-----1-213222212---------------2112231123211111111112121112111111111112111111111111111111111111--122222222221222222111122222211-21211111132-2222222222222222122----11---------11----1-111--------11----------------------------------21-11-------1-1-111------1--1111122111-1-112214---2111111-----142332122222211111111111-22122122112-1221111111113321223111112231111111121111311-----------------------------4213112222222222222222222322222222211211222222111211222222121211-------11212111213221112223-121122232111111111--1-11111----------2111311111222422222232312322223233223---3223------1111111111111-111-1111111111111111111111111111111--1---11111121111111--111111111111---111111111112222-----------1---222221312222222232233343312221-111111-21112222222342222111111111111111-221222--------------------------------------1--1-111111 11----1-1---11111121111111111211111111111111111111111122111111111111-11-11121-1111111111-12111111111121212-12-2---------------------------------------------------133154114115-1222V1113262281442272132 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 1467 STR:RPRED 96.5 SQ:SECSTR #####################cEEcEEEETTccccHHHHHHHHHHHTccGGGccccTTccccccccEEEEccHHHHHHHHHHTTccccccEEEEEEEEccccHHHHHHHHHHHHHHHHTTcEEEEEEEccccGGGccHHHHHHccEEEEEEEEcTTcccHHHHHHHHHHHHHHHHHHHHHHTccccEEEEEEccEEEccccccGGGHHHHcGGGGcTTccccEEEEEEccccccccccTTccccccEEEEEccTTHHHHHHHHHHHGGGccccTTGGGHHHHcccccTTccHHHHHHHHHHHHHHTTccHHHHHHHHcccccTTcccccHHHHHHHHHHHHHcccccccEEEEEccccEEEEEccTTcccccEEEEETTcEEEEccccTTccccGGGEEEEEEccTTcEEEEETTTTEEEcHHHHHHHHHHTTTHHHHHTTcccTTHHHHHHHHTTcTHHHHHHHHTTTccHHHHHTTTHHHHHHccccEEccccccccGGGccccccGGGTEEEcccccccccccTTTTGGGccccEEEcccccTTcccGGGcccEEEccccccHHHHHHHHHHHGGGEEEEEcEEEcTTHHHHHHHHHHHHHHHHHHHTccEEEEEcTTccTTEEEccHHHHHHHHHHHHHTTTcGGGcEEEEEccccccHHHHHHHHTTTccEEEcHHHHHHHHHHHTTTTTTccHHHHHHHHHHHHHHHHHHHHHTTTcccHHHHTTcccEEEccccHHHHHHHccccccccccccHHHHHHHHHHHHHHHHHcccccccccccccccccccccccccHHHHHHHHHHHHHTcHHHHHHHHHHHHTcccccGGGGEEEccccccccGGGcccHHHHHTTEEEEEcccTTccHHHHHHHHHHHHHTTcEEEccTTcccGGGccccTTcccccccEEEEccccTTccHHHHTcccEEEEEcccTTcTTTccEEcGGGccHHHHHHHTccTTccEEcccccTTcccHHHHHHHHHHHHHHcTTcEEEEEEEccTTHHHHHHHHHHTTccEEEEEcTTcccccEETTHHHHccccHHHHHHHHHHHHHTTTcTTTcEEEEEcccccHHHHHHHHHTTccEEEccHHHHHHHTccccccTTTTccTTccccccTTGGGcccccHHHHHHHHHHHHHHHHHHHHHHTccccGGGTTcGGGEEEcccccHHHcHHHHHHHHHHHHccccHccccccccccccccTHHHHHHHTHHHHHHcccEEEEEEEcTTcccTTHHHHHHHHHHTTTTcccTTcEEEEEEEEEcccTTTTccTTEEEEEEEEEcccTTTTcEEEEEEEEccTTccccGGGcEEEcccTTTTccEEEEEEccEEcTTTTTTcEEEEEEEccccccTTTTccEEEEEcTTEEccTTcHHHHHHHHHGGGGcccEHHHHHHHHEEEEEcccHHHHHHTTTccEcEEEEEccHHHHHHHHHHHHHHcccEEEcccHHHHHHHHEHHHHHHTT################################ DISOP:02AL 1520-1521| PSIPRED ccccccccccccccHHHcccccEEEEEEEccccccHHHHHHHHHHHHcccccccccccccccccEEEHHHHHHHHHHHHHHcccccccccEEEEEEEccccHHHHHHHHHHHHHHHHHcccEEEEEEccccccHHHcccHHHcccEEEEEEEccccccccHHHHHHHHHHHHHHHHHHHHcccccEEEEccccccEEEEccccHHHHHHHHHHccccccEEEEEEEEEcccccccccccccccEEEEEEccccccHHHHHHHHHHHHHHHccccHHHHHHHHcccccccccHHHHHHHHHHHHHHccccHHHHHHHHcccHHHHcccccHHHHHHHHHHHHHcccccccEEEEEEEccEEEEEEccccccEEEEEEEcccEEEEEEccEEEEccHHHEEEcccccccEEEEEEccccEEEccHHHHHHHHccccHHHHHHHHHEEccccccccccccHHHHHHHHHHHcccHHHHHHHHHHHHHccccEEEcccccccHHHHccccccHHHHHHHHHHHcccccccHHHHHHEEEEEEEEcccccccccccccccEEEEccccccHHHHHHHHHcccccccEEEEEccccHHHHHHHHHHHHHHHHHHHccccEEEEcccccccccccccHHHHHHHHHHHHHHccccccccEEEEccccccHHHHHHHHHHccccccHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccEEcccccHHHHHHHccccccEEccccHHHHHHHHHHHHHHHcccccccccccccEEEEccccccccccHHHHHHHHHHHHcccHHHHHHHHHHHHcccccHHHHHcccccccccccHHHcccHHHHcccEEEcccccccccHHHHHHHHHHHHHccccEEcccccccHHHHccccccccccEEEEEEccccccccHHHHccccEEEEEEEccccccccccccHHHccHHHHHHccccccccccccccccccccHHHHHHHHHHHHHHcccccEEEEEEccccHHHHHHHHHHHcccEEEEccccccccHHHHHHHHccccHHHHHHHHHHHHHHHccccccEEEEEEcccccHHHHHHHHHHcccEEHHcHHHHHHHHHHHHHHcccccccEEEEcccHHHHHHHcccHHHHHHHHHHHHHHHHHHHHHcccccHHHHHccHHHHcccccccccHHHcccccHHHHcccccccccccccccccccHHHHHHHHHHHHHHHHcccEEEEEEEEEEccccccHHHHHHHHHHHHHcccccccEEEEEEEccHHHHHcccccccEEEEEEcccccccccccccEEEEEccccccccccccEEccHHHHHcccccEEEEEcccccEEEEEccccEEEEEcccHHHHHHHHccEEEEEccHHHHHccccccEEEEEEccccccHHHHcccHHEEEEccccHHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHccEEEccHHHHHHHHHHHHHHHHcccHHHHHHHHHHHccccccHHHHccccccccc 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