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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : hutU
DDBJ      :hutU         urocanase
Swiss-Prot:HUTU_BACSU   RecName: Full=Urocanate hydratase;         Short=Urocanase;         EC=4.2.1.49;AltName: Full=Imidazolonepropionate hydrolase;

Homologs  Archaea  8/68 : Bacteria  347/915 : Eukaryota  60/199 : Viruses  0/175   --->[See Alignment]
e.51.1
:552 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   7->552 2fknB PDBj 0.0 100.0 %
:RPS:SCOP  8->550 1uwkA  e.51.1.1 * 0.0 61.0 %
:HMM:SCOP  4->553 1uwkA_ e.51.1.1 * 1e-257 64.2 %
:RPS:PFM   7->549 PF01175 * Urocanase 0.0 66.5 %
:HMM:PFM   8->551 PF01175 * Urocanase 7.4e-282 68.9 544/546  
:BLT:SWISS 1->552 HUTU_BACSU 0.0 100.0 %
:PROS 438->453|PS01233|UROCANASE
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB15972.1 GT:GENE hutU GT:PRODUCT urocanase GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 4043574..4045232 GB:FROM 4043574 GB:TO 4045232 GB:DIRECTION + GB:GENE hutU GB:PRODUCT urocanase GB:FUNCTION 16.11: Scavenge (Catabolism) GB:NOTE Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15313616, 17395359; Product type e: enzyme GB:PROTEIN_ID CAB15972.1 GB:DB_XREF GOA:P25503 InterPro:IPR000193 PDB:2FKN SubtiList:BG10668 UniProtKB/Swiss-Prot:P25503 GB:GENE:GENE hutU LENGTH 552 SQ:AASEQ MTDVKKSIRANRGTELECLGWEQEAVLRMLRNNLDPEVAEKPEDLIVYGGIGKAARDWDAFHAIEHSLKTLKNDETLLVQSGKPVGMFRTHPQAPRVLLANSVLVPKWADWEHFHELEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKGTLTLTAGLGGMGGAQPLSVTMNEGVVIAVEVDEKRIDKRIETKYCDRKTASIEEALAWAEEAKLAGKPLSIALLGNAAEVHHTLLNRGVKIDIVTDQTSAHDPLIGYVPEGYSLDEADRLRQDTPELYVRLAKQSMKKHVEAMLAFQQKGSIVFDYGNNIRQVAKDEGLENAFDFPGFVPAYIRPLFCEGKGPFRWAALSGDPADIYRTDALLKELFPTNKALHRWIDMAQEKVTFQGLPSRICWLGYGERKKMGLAINELVRTGELKAPVVIGRDHLDCGSVASPNRETEAMKDGSDAVGDWAVLNALVNTAAGASWVSFHHGGGVGMGYSLHAGMVAVADGSELADERLARVLTSDPGMGIIRHADAGYERAVEVAKEQDIIVPMQK GT:EXON 1|1-552:0| SW:ID HUTU_BACSU SW:DE RecName: Full=Urocanate hydratase; Short=Urocanase; EC=4.2.1.49;AltName: Full=Imidazolonepropionate hydrolase; SW:GN Name=hutU; OrderedLocusNames=BSU39360; ORFNames=EE57A; SW:KW 3D-structure; Complete proteome; Cytoplasm; Histidine metabolism;Lyase; NAD. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->552|HUTU_BACSU|0.0|100.0|552/552| GO:SWS:NREP 3 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0006547|"GO:histidine metabolic process"|Histidine metabolism| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| PROS 438->453|PS01233|UROCANASE|PDOC00947| SEG 158->176|ggslkgtltltaglggmgg| SEG 216->228|eealawaeeakla| BL:PDB:NREP 1 BL:PDB:REP 7->552|2fknB|0.0|100.0|546/546| RP:PFM:NREP 1 RP:PFM:REP 7->549|PF01175|0.0|66.5|543/545|Urocanase| HM:PFM:NREP 1 HM:PFM:REP 8->551|PF01175|7.4e-282|68.9|544/546|Urocanase| GO:PFM:NREP 2 GO:PFM GO:0006548|"GO:histidine catabolic process"|PF01175|IPR000193| GO:PFM GO:0016153|"GO:urocanate hydratase activity"|PF01175|IPR000193| RP:SCP:NREP 1 RP:SCP:REP 8->550|1uwkA|0.0|61.0|543/554|e.51.1.1| HM:SCP:REP 4->553|1uwkA_|1e-257|64.2|550/554|e.51.1.1|1/1|Urocanase| OP:NHOMO 458 OP:NHOMOORG 415 OP:PATTERN -----------------1-1----111----------------------------------111---- -11111-------------------1----------1111----1111----111111--11111-1111------------1-----1111-111---1-11111---1--------------------------111-----1--------------------------------------111-------111111111111111111---11111111---------1-1111111111111111---1-----------------------------1---1-------------11111111111111--11------11---------------------1---1-----------1---11-12-1--1111-------111--------11111111111---1--1--31--211122122211---11--21-11111--------1--1--11--------------------------------11------1111111111111112221212112322--111--1--1-2-11-------1-----------1--1-2-1-------------------111111-1---------------------------11-1--111111111111111111111111-------------1-11-11-------------------1----------111--11-111-11111111-1-11---------111111111111---1-----1111--1-1---------------111211--111-1111111111111-111----------111111111111111111111111----------------------1---------------------------11111-1------ ----11-----------------------------------------------------------------------------------------------------1-2222122-111111112-21231-212--1-21111--11-11-1-11111321111-----1111--1----------1-----21221 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 546 STR:RPRED 98.9 SQ:SECSTR ######ccccccccccccccHHHHHHHHHHHHTTcTTTcccGGGTEEETTTEEccccHHHHHHHHHHHHHccTTEEEEEETTEEEEEEEccTTcccEEEEEccccGGGccHHHHHHHHHTTcccccTTTTTTTcccTTHHHHHHHHHHHHHHHHHHcTTccTTcEEEEEcccTTTTHHHHHHHTTTcEEEEEEccHHHHHHHHHTTcccEEEccHHHHHHHHHHHHHHTccEEEEEEccHHHHHHHHHHTTccccEEcccccTTcTTTccccTTccHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHTTcEEccccccHHHHHHHHTcTTGGGcccHHHHTTHHHHTTTcccEEEEETTccHHHHHHHHHHHHHHcTTcHHHHHHHHHHHHHcccccccEEEccccTTHHHHHHHHHHHHHHHTcccccEEEEEccccTTcEEcTTTTTTTcTTccTTccHHHHHHHHHHHHHTccEEEEEEcTTTcTTccEEEEEEEEEcccHHHHHHHHHHHHHHHHHHHHHHHHHTcHHHHHHHHHHTcccTTcc DISOP:02AL 1-4| PSIPRED ccccccEEEcccccccccccHHHHHHHHHHHHcccHHHHcccccEEEEccccHHHccHHHHHHHHHHHHccccccEEEEEcccEEEEccccccccEEEEEEcccccccccHHHHHHHHHcccccccccccccEEEEccccEEEHHHHHHHHHHHHHHccccEEEEEEEEcccccccccHHHHHHccEEEEEEEccHHHHHHHHHHccHHHHcccHHHHHHHHHHHHHccccEEEEEcccHHHHHHHHHHcccEEEEEcccccccccccccccccccHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEccHHHHHHHHHcccHHcccccccHHHHHHHHHHcccccEEEEEEcccHHHHHHHHHHHHHHccccHHHHHHHHHHHHcccccccHHHHHHcccHHHHHHHHHHHHHHHcccccccEEEEcccccccccccccHHHHcccccHHHHHHHHHHHHHHHHHcccEEEEEEEcccEEEEEEEEccEEEEEcccHHHHHHHHHHHcccccccEEEEcccccHHHHHHHHHccccccccc //