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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : lytF
DDBJ      :lytF         gamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin)
Swiss-Prot:LYTF_BACSU   RecName: Full=Endopeptidase lytF;         EC=3.4.-.-;AltName: Full=Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF;AltName: Full=Cell wall-associated polypeptide CWBP49;Flags: Precursor;

Homologs  Archaea  0/68 : Bacteria  506/915 : Eukaryota  3/199 : Viruses  1/175   --->[See Alignment]
d.3.1d.7.1
:488 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   28->71 1y7mA PDBj 8e-04 40.9 %
:BLT:PDB   385->486 2k1gA PDBj 6e-17 45.5 %
:RPS:PDB   22->71 2djpA PDBj 7e-09 25.5 %
:RPS:PDB   100->137 2djpA PDBj 6e-07 25.6 %
:RPS:PDB   173->215 2djpA PDBj 4e-08 25.0 %
:RPS:PDB   239->283 1e01A PDBj 5e-11 29.5 %
:RPS:PDB   317->349 2djpA PDBj 1e-04 32.4 %
:RPS:SCOP  28->71 1y7mA2  d.7.1.1 * 4e-11 40.9 %
:RPS:SCOP  100->137 1y7mA2  d.7.1.1 * 2e-07 28.9 %
:RPS:SCOP  175->215 1y7mA2  d.7.1.1 * 3e-08 31.7 %
:RPS:SCOP  239->283 1e0gA  d.7.1.1 * 2e-11 29.5 %
:RPS:SCOP  317->349 1y7mA2  d.7.1.1 * 3e-05 27.3 %
:RPS:SCOP  377->488 2evrA2  d.3.1.16 * 8e-33 29.7 %
:HMM:SCOP  25->73 1e0gA_ d.7.1.1 * 1.3e-09 41.7 %
:HMM:SCOP  90->138 1e0gA_ d.7.1.1 * 9.6e-11 47.9 %
:HMM:SCOP  172->220 1e0gA_ d.7.1.1 * 3.3e-08 39.6 %
:HMM:SCOP  238->286 1e0gA_ d.7.1.1 * 6.3e-12 41.7 %
:HMM:SCOP  306->353 1y7mA2 d.7.1.1 * 5.6e-12 45.8 %
:HMM:SCOP  361->488 2evrA2 d.3.1.16 * 1.3e-38 43.3 %
:RPS:PFM   31->70 PF01476 * LysM 2e-04 51.2 %
:RPS:PFM   176->215 PF01476 * LysM 6e-04 43.9 %
:RPS:PFM   242->281 PF01476 * LysM 2e-06 55.0 %
:RPS:PFM   385->480 PF00877 * NLPC_P60 3e-19 45.8 %
:HMM:PFM   30->71 PF01476 * LysM 2.3e-16 47.6 42/44  
:HMM:PFM   94->136 PF01476 * LysM 7.5e-19 48.8 43/44  
:HMM:PFM   176->216 PF01476 * LysM 1.6e-14 46.3 41/44  
:HMM:PFM   242->283 PF01476 * LysM 6e-20 52.4 42/44  
:HMM:PFM   309->351 PF01476 * LysM 1.6e-18 48.8 43/44  
:HMM:PFM   385->485 PF00877 * NLPC_P60 1.8e-31 47.5 99/105  
:BLT:SWISS 1->488 LYTF_BACSU 0.0 100.0 %
:REPEAT 5|35->68|100->133|182->215|248->281|313->348
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB12776.2 GT:GENE lytF GT:PRODUCT gamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin) GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION complement(1011792..1013258) GB:FROM 1011792 GB:TO 1013258 GB:DIRECTION - GB:GENE lytF GB:PRODUCT gamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin) GB:FUNCTION 16.13: Shape GB:NOTE Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10206711, 14594841, 18761694, 18761696; Product type e: enzyme GB:PROTEIN_ID CAB12776.2 GB:DB_XREF GOA:O07532 InterPro:IPR002482 SubtiList:BG13010 UniProtKB/Swiss-Prot:O07532 GB:GENE:GENE lytF LENGTH 488 SQ:AASEQ MKKKLAAGLTASAIVGTTLVVTPAEAATIKVKSGDSLWKLAQTYNTSVAALTSANHLSTTVLSIGQTLTIPGSKSSTSSSTSSSTTKKSGSSVYTVKSGDSLWLIANEFKMTVQELKKLNGLSSDLIRAGQKLKVSGTVSSSSSSSKKSNSNKSSSSSSKSSSNKSSSSSSSTGTYKVQLGDSLWKIANKVNMSIAELKVLNNLKSDTIYVNQVLKTKSSGSDTSSKDNSSKSNQTSATTKYTVKSGDSLWKIANNYNLTVQQIRNINNLKSDVLYVGQVLKLTGKASSGSSSSSSSSSNASSGTTTTYTVKSGDSLWVIAQKFNVTAQQIREKNNLKTDVLQVGQKLVISGKASSSSSSGSSNTTSSTSAKINTMISAAKAQLGVPYRWGGTTPSGFDCSGFIYYVLNKVTSVSRLTAAGYWNTMKSVSQPAVGDFVFFSTYKAGPSHVGIYLGNGEFINANDSGVVISNMNNSYWKQRYLGAKRYF GT:EXON 1|1-488:0| SW:ID LYTF_BACSU SW:DE RecName: Full=Endopeptidase lytF; EC=3.4.-.-;AltName: Full=Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF;AltName: Full=Cell wall-associated polypeptide CWBP49;Flags: Precursor; SW:GN Name=lytF; Synonyms=yhdD; OrderedLocusNames=BSU09370; SW:KW Cell wall; Cell wall biogenesis/degradation; Complete proteome;Direct protein sequencing; Hydrolase; Repeat; Secreted; Signal. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->488|LYTF_BACSU|0.0|100.0|488/488| GO:SWS:NREP 4 GO:SWS GO:0005618|"GO:cell wall"|Cell wall| GO:SWS GO:0007047|"GO:cellular cell wall organization"|Cell wall biogenesis/degradation| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0005576|"GO:extracellular region"|Secreted| NREPEAT 1 REPEAT 5|35->68|100->133|182->215|248->281|313->348| SEG 72->99|gsksstssstsssttkksgssvytvksg| SEG 140->172|ssssssskksnsnkssssssksssnksssssss| SEG 216->237|ktkssgsdtsskdnssksnqts| SEG 284->316|tgkassgsssssssssnassgttttytvksgds| SEG 350->375|isgkassssssgssnttsstsakint| BL:PDB:NREP 2 BL:PDB:REP 28->71|1y7mA|8e-04|40.9|44/161| BL:PDB:REP 385->486|2k1gA|6e-17|45.5|101/129| RP:PDB:NREP 5 RP:PDB:REP 22->71|2djpA|7e-09|25.5|50/77| RP:PDB:REP 100->137|2djpA|6e-07|25.6|38/77| RP:PDB:REP 173->215|2djpA|4e-08|25.0|43/77| RP:PDB:REP 239->283|1e01A|5e-11|29.5|44/48| RP:PDB:REP 317->349|2djpA|1e-04|32.4|33/77| RP:PFM:NREP 4 RP:PFM:REP 31->70|PF01476|2e-04|51.2|40/44|LysM| RP:PFM:REP 176->215|PF01476|6e-04|43.9|40/44|LysM| RP:PFM:REP 242->281|PF01476|2e-06|55.0|40/44|LysM| RP:PFM:REP 385->480|PF00877|3e-19|45.8|96/100|NLPC_P60| HM:PFM:NREP 6 HM:PFM:REP 30->71|PF01476|2.3e-16|47.6|42/44|LysM| HM:PFM:REP 94->136|PF01476|7.5e-19|48.8|43/44|LysM| HM:PFM:REP 176->216|PF01476|1.6e-14|46.3|41/44|LysM| HM:PFM:REP 242->283|PF01476|6e-20|52.4|42/44|LysM| HM:PFM:REP 309->351|PF01476|1.6e-18|48.8|43/44|LysM| HM:PFM:REP 385->485|PF00877|1.8e-31|47.5|99/105|NLPC_P60| GO:PFM:NREP 3 GO:PFM GO:0016998|"GO:cell wall macromolecule catabolic process"|PF01476|IPR018392| GO:PFM GO:0016998|"GO:cell wall macromolecule catabolic process"|PF01476|IPR018392| GO:PFM GO:0016998|"GO:cell wall macromolecule catabolic process"|PF01476|IPR018392| RP:SCP:NREP 6 RP:SCP:REP 28->71|1y7mA2|4e-11|40.9|44/48|d.7.1.1| RP:SCP:REP 100->137|1y7mA2|2e-07|28.9|38/48|d.7.1.1| RP:SCP:REP 175->215|1y7mA2|3e-08|31.7|41/48|d.7.1.1| RP:SCP:REP 239->283|1e0gA|2e-11|29.5|44/48|d.7.1.1| RP:SCP:REP 317->349|1y7mA2|3e-05|27.3|33/48|d.7.1.1| RP:SCP:REP 377->488|2evrA2|8e-33|29.7|111/148|d.3.1.16| HM:SCP:REP 25->73|1e0gA_|1.3e-09|41.7|48/48|d.7.1.1|1/5|LysM domain| HM:SCP:REP 90->138|1e0gA_|9.6e-11|47.9|48/48|d.7.1.1|2/5|LysM domain| HM:SCP:REP 172->220|1e0gA_|3.3e-08|39.6|48/48|d.7.1.1|3/5|LysM domain| HM:SCP:REP 238->286|1e0gA_|6.3e-12|41.7|48/48|d.7.1.1|4/5|LysM domain| HM:SCP:REP 306->353|1y7mA2|5.6e-12|45.8|48/0|d.7.1.1|5/5|LysM domain| HM:SCP:REP 361->488|2evrA2|1.3e-38|43.3|127/0|d.3.1.16|1/1|Cysteine proteinases| OP:NHOMO 1163 OP:NHOMOORG 510 OP:PATTERN -------------------------------------------------------------------- -11-2222222211-11----11111-----11122--232213312-1111-1---1--11-11--1216--------22-1-2-11111--1-----111-1-12--1---------------222222-121111111---21-------------------------------------22311---336344553354454555317757443534554465565521311111111111211111-24254223111-214422311-111111------------111-11-1--------1-----11---2-1-1214744456752516C2211--22313--3215423213-122221--2-1-----------------------------------------------------------------------------------------------------------------------------22222222222222222222222222222222212222112222212212221111222222222211222--1-11-11212221333222222------211----1111---1-------1---122221-------1111111111112-111211--1---1------45333434444444344-4444444444444444444444332223333333333333333334434442-333333333333---1---------1112-111211122211--1----------2-44443334433333333----------2223222222212222212112222222------1111--------1---------------------------1-----1------ --------------------------------------------------------------------------------------------------------------------------------------------------------------1-----------------------------1-----1---- --------------------------------------------------------------------------------------------------------------1---------------------------------------------------------------- STR:NPRED 315 STR:RPRED 64.5 SQ:SECSTR #####################ccEccEEEEEcTTccHHHHHHHHTccHHHHHHHcccccccccTTEEEEEc############################ccHHHHHHHHTccHHHHHHHcccccccccTTEEEEEEE###################################EEEEEEcTTccHHHHHHHHTccHHHHHHHcccccccccTTEEE#######################cEEEEEcTTccHHHHHHHHTccHHHHHHHcccccccccTTEEEEE#################################HHHHHHHHTccHHHHHHHcccccccccTTEEEE###############################HHTcTcccccccccTTcccHHHHHHHHHHHTTcccccccHHHHGGGEEEcGGGcTEEEEEEETTTEEEEEEEEEETTEEEEEETTEEEEEETTcHHHHHHEEEEEE## PSIPRED ccccccccccccccccccccccccccEEEEEcccccHHHHHHHHcccHHHHHHHcccccccEEcccEEEccccccccccccccccccccccccEEEcccccHHHHHHHHcccHHHHHHHccccccccccccEEEccccccccccccccccccccccccccccccccccccccccccccccccHHHHHHHHHcccHHHHHHHcccccccEEcccEEEEEccccccccccccccccccccccEEEEcccccHHHHHHHHcccHHHHHHHcccccccEEccEEEEEccccccccccccccccccccccccEEEEcccccHHHHHHHccccHHHHHHHcccccccccccccEEEcccccccccccccccccccccccHHHHHHHHHHcccccccccccccccccHHHHHHHHHHHcccccccHHHHHHHcccHHHcccccEEEEccccccccEEEEEEEccEEEEEccccEEEEEccccHHHccEEEEEEcc //