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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : metC
DDBJ      :metC         cystathionine beta-lyase
Swiss-Prot:METC_BACSU   RecName: Full=Cystathionine beta-lyase metC;         Short=CBL;         EC=4.4.1.8;AltName: Full=Beta-cystathionase;AltName: Full=Cysteine lyase;

Homologs  Archaea  47/68 : Bacteria  756/915 : Eukaryota  190/199 : Viruses  0/175   --->[See Alignment]
c.67.1
:390 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   25->382 1ibjA PDBj 2e-94 46.4 %
:RPS:PDB   8->380 3e6gA PDBj e-122 47.8 %
:RPS:SCOP  8->384 1cs1A  c.67.1.3 * 4e-78 39.0 %
:HMM:SCOP  9->387 1cs1A_ c.67.1.3 * 8.5e-120 40.9 %
:RPS:PFM   10->381 PF01053 * Cys_Met_Meta_PP e-107 54.2 %
:HMM:PFM   9->382 PF01053 * Cys_Met_Meta_PP 3.2e-154 56.1 374/386  
:BLT:SWISS 1->390 METC_BACSU 0.0 100.0 %
:PROS 192->206|PS00868|CYS_MET_METAB_PP

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB13045.1 GT:GENE metC GT:PRODUCT cystathionine beta-lyase GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 1259606..1260778 GB:FROM 1259606 GB:TO 1260778 GB:DIRECTION + GB:GENE metC GB:PRODUCT cystathionine beta-lyase GB:FUNCTION 16.2: Construct biomass (Anabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11832514, 11948165; Product type e: enzyme GB:PROTEIN_ID CAB13045.1 GB:DB_XREF GOA:O31632 HSSP:1IBJ InterPro:IPR015422 SubtiList:BG13163 UniProtKB/Swiss-Prot:O31632 GB:GENE:GENE metC LENGTH 390 SQ:AASEQ MSKHNWTLETQLVHNPFKTDGGTGAVSVPIQHASTFHQSSFEEFGAYDYSRSGTPTRTALEETIAALEGGTRGFAFSSGMAAISTAFLLLSQGDHVLVTEDVYGGTFRMVTEVLTRFGIEHTFVDMTDRNEVARSIKPNTKVIYMETPSNPTLGITDIKAVVQLAKENGCLTFLDNTFMTPALQRPLDLGVDIVLHSATKFLSGHSDVLSGLAAVKDEELGKQLYKLQNAFGAVLGVQDCWLVLRGLKTLQVRLEKASQTAQRLAEFFQKHPAVKRVYYPGLADHPGAETHKSQSTGAGAVLSFELESKEAVKKLVENVSLPVFAVSLGAVESILSYPATMSHAAMPKEEREKRGITDGLLRLSVGVEHADDLEHDFEQALKEIAPVSVR GT:EXON 1|1-390:0| SW:ID METC_BACSU SW:DE RecName: Full=Cystathionine beta-lyase metC; Short=CBL; EC=4.4.1.8;AltName: Full=Beta-cystathionase;AltName: Full=Cysteine lyase; SW:GN Name=metC; Synonyms=yjcJ; OrderedLocusNames=BSU11880; SW:KW Amino-acid biosynthesis; Complete proteome; Cytoplasm; Lyase;Methionine biosynthesis; Pyridoxal phosphate. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->390|METC_BACSU|0.0|100.0|390/390| GO:SWS:NREP 4 GO:SWS GO:0008652|"GO:cellular amino acid biosynthetic process"|Amino-acid biosynthesis| GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016829|"GO:lyase activity"|Lyase| GO:SWS GO:0009086|"GO:methionine biosynthetic process"|Methionine biosynthesis| PROS 192->206|PS00868|CYS_MET_METAB_PP|PDOC00677| BL:PDB:NREP 1 BL:PDB:REP 25->382|1ibjA|2e-94|46.4|358/380| RP:PDB:NREP 1 RP:PDB:REP 8->380|3e6gA|e-122|47.8|362/368| RP:PFM:NREP 1 RP:PFM:REP 10->381|PF01053|e-107|54.2|371/384|Cys_Met_Meta_PP| HM:PFM:NREP 1 HM:PFM:REP 9->382|PF01053|3.2e-154|56.1|374/386|Cys_Met_Meta_PP| GO:PFM:NREP 2 GO:PFM GO:0006520|"GO:cellular amino acid metabolic process"|PF01053|IPR000277| GO:PFM GO:0030170|"GO:pyridoxal phosphate binding"|PF01053|IPR000277| RP:SCP:NREP 1 RP:SCP:REP 8->384|1cs1A|4e-78|39.0|377/384|c.67.1.3| HM:SCP:REP 9->387|1cs1A_|8.5e-120|40.9|379/0|c.67.1.3|1/1|PLP-dependent transferases| OP:NHOMO 3126 OP:NHOMOORG 993 OP:PATTERN 22-1-11111111111-111111-3332233321--------1451-1-1221-111-1--2221--- 1741421233222144433-34223533333244443567133365423442446566--324-433334345554441-131-----33222211---11435442344---------------2323322431144444---43---2--1--11333331----2-1-33323333323334322--12435555555555555556633435553453511333333752333333333333323334422-11113-1-331112-1-253323-------222122221211111111111112111222333222-241573333333231227721113241-6333-22--1-242333321317-33335-----35867543C567544444443446167766846783-555666665866443543434544345222222224222335811-----------------------11112346424643463344754444333844441453465441143343555745665323111343222222222244221123-2-241----565354423445442112231122212112111111123121113332314434335455444444544355442--3321------52332332222222222-2222222232222222223333334462222222222222222422222222-32233333333322-311111111112214333334-22212223333332312231333344251656424221--------122232222223422332323333311111131221122--------1----------------------------11--22222-32 ----213-631-675565567869796444544574754544555555676AB86655555555645535635558846765555543-68465493222333544-4734151121111111122111372-2131121111211111111111111211135241112233523235n4443465696644343335 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 388 STR:RPRED 99.5 SQ:SECSTR cccccTTHHHHHHHTTccccTTTcccccccccccccccccccHHHHccccccccHHHHHHHHHHHHHHTccEEEEEccHHHHHHHHHTTccTTcEEEEEccccHHHHHHHHHHHHHHccEEEEEcTTcHHHHHHHccTTEEEEEEEcccTTTcccccHHHHHHHHHHTTcEEEEEcccccTTTccGGGGTccEEEEETTTTTTcccccccEEEEEccHHHHHHHHHHHHHHcccccHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHTcTTEEEEEcTTcTTcTTHHHHHHHccccccEEEEEETHHHHHHHHHHHccccEEcccccccccEEEcTTTTTTcccccTTTTTccccccEEEEEcccccHHHHHHHHTTcTHHHcccc## DISOP:02AL 1-5| PSIPRED cccccccccHHHEEcccccccccccccccccccEEEEEcccccccccEEcccccHHHHHHHHHHHHHHcccEEEEEccHHHHHHHHHHHHccccEEEEEccccHHHHHHHHHHHHHcccEEEEEccccHHHHHHHccccccEEEEEcccccccccccHHHHHHHHHHcccEEEEEcccccccccccHHHcccEEEEEccccccccHHHcccEEEEccHHHHHHHHHHHHHHcccccHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHccccccHHHcccccccccHHHHHHHHccccEEEEEEEccHHHHHHHHHHcccEEEEccccccEEEEEEcccHHHHcccHHHHHHccccccEEEEEEEcccHHHHHHHHHHHHHHHcccccc //