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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : mtlA
DDBJ      :mtlA         phosphotransferase system (PTS) mannitol-specific enzyme IICB component
Swiss-Prot:PTMCB_BACSU  RecName: Full=PTS system mannitol-specific EIICB component;AltName: Full=EIICB-Mtl;         Short=EII-Mtl;Includes:  RecName: Full=Mannitol permease IIC component;  AltName: Full=PTS system mannitol-specific EIIC component;Includes:  RecName: Full=Mannitol-specific phosphotransferase enzyme IIB component;           EC=2.7.1.69;  AltName: Full=PTS system mannitol-specific EIIB component;

Homologs  Archaea  0/68 : Bacteria  197/915 : Eukaryota  1/199 : Viruses  0/175   --->[See Alignment]
c.44.2c.8.2
:478 amino acids
:SECSTR
:PSIPRED
:BLT:PDB   389->476 1vkrA PDBj 3e-20 53.4 %
:RPS:PDB   391->477 3czcA PDBj 4e-12 22.1 %
:RPS:SCOP  170->272 1l5jA2  c.8.2.1 * 7e-10 18.4 %
:RPS:SCOP  391->478 1vkrA  c.44.2.1 * 2e-28 63.6 %
:HMM:SCOP  387->478 1vkrA_ c.44.2.1 * 1.9e-26 40.2 %
:HMM:PFM   24->282 PF02378 * PTS_EIIC 5.5e-20 22.2 248/321  
:HMM:PFM   391->475 PF02302 * PTS_IIB 5.8e-15 22.4 85/90  
:HMM:PFM   320->382 PF04612 * GspM 0.00064 16.1 62/160  
:BLT:SWISS 17->478 PTMCB_BACSU 0.0 100.0 %
:TM
:COIL
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB12206.2 GT:GENE mtlA GT:PRODUCT phosphotransferase system (PTS) mannitol-specific enzyme IICB component GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 449724..451160 GB:FROM 449724 GB:TO 451160 GB:DIRECTION + GB:GENE mtlA GB:PRODUCT phosphotransferase system (PTS) mannitol-specific enzyme IICB component GB:FUNCTION 16.1: Circulate 16.11: Scavenge (Catabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type t: transporter GB:PROTEIN_ID CAB12206.2 GB:DB_XREF GOA:P42956 HSSP:1A3A InterPro:IPR004718 SubtiList:BG11215 UniProtKB/Swiss-Prot:P42956 GB:GENE:GENE mtlA LENGTH 478 SQ:AASEQ MQQQEQQQGGMKVKVQRFGSYLSGMIMPNIGAFIAWGIITALFIPAGWFPNEQLNTLVSPMITYLLPLLIAYTGGKMIYDHRGGVVGATAAIGVIVGSDIPMFLGAMIMGPLGGYLIKQTDKLFKDKVKQGFEMLINNFTAGIVGAALTILAFYAIGPVVLTLNKLLAAGVEVIVHANLLPVASVFVEPAKVLFLNNAINHGILSPIGIEQASQTGKSILFLVEANPGPGLGILLAYMFFGKGSSKSTAPGAAIIHFFGGIHEIYFPYILMKPALILAAIAGGASGLLTFTIFNAGLVAAASPGSIIALMAMTPRGGYFGVLAGVLVAAAVSFIVSAVILKSSKASEEDLAAATEKMQSMKGKKSQAAAALEAEQAKAEEASELSPESVNKIIFACDAGMGSSAMGASILRNKVKKAELDISVTNTAINNLPSDADIVITHKDLTDRAKAKLPNATHISVDNFLNSPKYDELIEKLKK GT:EXON 1|1-478:0| SW:ID PTMCB_BACSU SW:DE RecName: Full=PTS system mannitol-specific EIICB component;AltName: Full=EIICB-Mtl; Short=EII-Mtl;Includes: RecName: Full=Mannitol permease IIC component; AltName: Full=PTS system mannitol-specific EIIC component;Includes: RecName: Full=Mannitol-specific phosphotransferase enzyme IIB component; EC=2.7.1.69; AltName: Full=PTS system mannitol-specific EIIB component; SW:GN Name=mtlA; OrderedLocusNames=BSU03981; ORFNames=BSU03980; SW:KW Cell membrane; Complete proteome; Kinase; Membrane;Phosphotransferase system; Sugar transport; Transferase;Transmembrane; Transport. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 17->478|PTMCB_BACSU|0.0|100.0|462/478| GO:SWS:NREP 8 GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0016301|"GO:kinase activity"|Kinase| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0009401|"GO:phosphoenolpyruvate-dependent sugar phosphotransferase system"|Phosphotransferase system| GO:SWS GO:0008643|"GO:carbohydrate transport"|Sugar transport| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| GO:SWS GO:0016021|"GO:integral to membrane"|Transmembrane| GO:SWS GO:0006810|"GO:transport"|Transport| COIL:NAA 37 COIL:NSEG 1 COIL:REGION 347->383| TM:NTM 7 TM:REGION 24->46| TM:REGION 55->77| TM:REGION 90->112| TM:REGION 140->162| TM:REGION 165->187| TM:REGION 280->302| TM:REGION 320->342| SEG 1->16|mqqqeqqqggmkvkvq| SEG 83->97|ggvvgataaigvivg| SEG 274->288|alilaaiaggasgll| SEG 320->340|gvlagvlvaaavsfivsavil| SEG 363->385|kksqaaaaleaeqakaeeasels| BL:PDB:NREP 1 BL:PDB:REP 389->476|1vkrA|3e-20|53.4|88/97| RP:PDB:NREP 1 RP:PDB:REP 391->477|3czcA|4e-12|22.1|86/89| HM:PFM:NREP 3 HM:PFM:REP 24->282|PF02378|5.5e-20|22.2|248/321|PTS_EIIC| HM:PFM:REP 391->475|PF02302|5.8e-15|22.4|85/90|PTS_IIB| HM:PFM:REP 320->382|PF04612|0.00064|16.1|62/160|GspM| RP:SCP:NREP 2 RP:SCP:REP 170->272|1l5jA2|7e-10|18.4|98/212|c.8.2.1| RP:SCP:REP 391->478|1vkrA|2e-28|63.6|88/97|c.44.2.1| HM:SCP:REP 387->478|1vkrA_|1.9e-26|40.2|92/0|c.44.2.1|1/1|PTS system, Lactose/Cellobiose specific IIB subunit| OP:NHOMO 245 OP:NHOMOORG 198 OP:PATTERN -------------------------------------------------------------------- ----2----------------1----------1----------2--1--111111-----2-11--------------------------------------------------------------------------------2----------------------------------------------111---------------111-11----11-11111111-11-111111111111111--112---12-----11--11-1-----11--------1111111111-1-----1-----------------2-2-12-----------1--------------------------111------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1--------------------------------------------------------111-------2--------------------------11-11121-1-112222222222-221212222222222222212111---1211121211111111122111111-111111111111------------------1111-1------111---------------------------------------11111111112-11-------------------------------------------21---111-1-12----------------- -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 89 STR:RPRED 18.6 SQ:SECSTR ####################################################################################################################################################################################################################################################################################################################################################################################################ccEEEEEccccHHHHHHHHHHHHHHTTcccEEEEEEcHHHHHHGGGccEEEEETTTGGGTTTcccccEEEEEccTcHHHHHHHHHHHHc# PSIPRED ccccccccccEEEEHHHHHHHHcccccccHHHHHHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHccHHcccccHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHccHHHHHHHHHHHHHHHHHHHHHHHHHcccEEEEEEcccccccHHHHHHHHHHcccHHHHcccHHHHHHHHccHHHHHHHHHHHHHHHHHHHHccccHHHHHEEHcccccccccccHHHHHHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccHHHcEEEEEEEEccccHHHHHHHHHHHHHHHccccEEEEEEEHHHccccccEEEEEHHHHHHHHHHcccccEEEHHHHcccHHHHHHHHHHcc //