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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : nadC
DDBJ      :nadC         nicotinate-nucleotide pyrophosphorylase
Swiss-Prot:NADC_BACSU   RecName: Full=Probable nicotinate-nucleotide pyrophosphorylase [carboxylating];         EC=2.4.2.19;AltName: Full=Quinolinate phosphoribosyltransferase [decarboxylating];         Short=QAPRTase;AltName: Full=General stress protein 70;         Short=GSP70;

Homologs  Archaea  53/68 : Bacteria  687/915 : Eukaryota  152/199 : Viruses  0/175   --->[See Alignment]
c.1.17d.41.2
:289 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   16->272 1qapA PDBj 4e-49 41.0 %
:RPS:PDB   5->274 3c2vA PDBj 8e-52 34.5 %
:RPS:SCOP  4->107 1qapA2  d.41.2.1 * 3e-20 32.7 %
:RPS:SCOP  108->274 1o4uA1  c.1.17.1 * 1e-36 39.5 %
:HMM:SCOP  1->107 1qapA2 d.41.2.1 * 9.6e-31 42.1 %
:HMM:SCOP  108->276 1o4uA1 c.1.17.1 * 6.4e-60 50.9 %
:RPS:PFM   19->106 PF02749 * QRPTase_N 8e-18 46.6 %
:RPS:PFM   108->273 PF01729 * QRPTase_C 4e-51 59.0 %
:HMM:PFM   108->273 PF01729 * QRPTase_C 6.2e-68 52.4 166/169  
:HMM:PFM   18->106 PF02749 * QRPTase_N 4.2e-28 44.8 87/88  
:BLT:SWISS 1->289 NADC_BACSU e-166 100.0 %

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB14746.1 GT:GENE nadC GT:PRODUCT nicotinate-nucleotide pyrophosphorylase GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION complement(2847048..2847917) GB:FROM 2847048 GB:TO 2847917 GB:DIRECTION - GB:GENE nadC GB:PRODUCT nicotinate-nucleotide pyrophosphorylase GB:FUNCTION 16.2: Construct biomass (Anabolism) GB:NOTE Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8419294; Product type e: enzyme GB:PROTEIN_ID CAB14746.1 GB:DB_XREF GOA:P39666 HSSP:1QAP InterPro:IPR002638 SubtiList:BG10868 UniProtKB/Swiss-Prot:P39666 GB:GENE:GENE nadC LENGTH 289 SQ:AASEQ MNHLQLKKLLNHFFLEDIGTGDLTSQSIFGEQSCEAEIVAKSEGIFAGAAIIKEGFSLLDENVQSILHKKDGDMLHKGEVIAELHGPAAALLSGERVVLNLIQRLSGIATMTREAVRCLDDEQIKICDTRKTTPGLRMLEKYAVRAGGGYNHRFGLYDGIMIKDNHIAACGSILEACKKARQAAGHMVNIEVEIETEEQLREAIAAGADVIMFDNCPPDTVRHFAKLTPANIKTEASGGITLESLPAFKGTGVNYISLGFLTHSVKSLDISMDVTLSNESVEECCYVNS GT:EXON 1|1-289:0| SW:ID NADC_BACSU SW:DE RecName: Full=Probable nicotinate-nucleotide pyrophosphorylase [carboxylating]; EC=2.4.2.19;AltName: Full=Quinolinate phosphoribosyltransferase [decarboxylating]; Short=QAPRTase;AltName: Full=General stress protein 70; Short=GSP70; SW:GN Name=nadC; Synonyms=yrxB; OrderedLocusNames=BSU27860; SW:KW Complete proteome; Direct protein sequencing; Glycosyltransferase;Pyridine nucleotide biosynthesis; Stress response; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->289|NADC_BACSU|e-166|100.0|289/289| GO:SWS:NREP 4 GO:SWS GO:0016757|"GO:transferase activity, transferring glycosyl groups"|Glycosyltransferase| GO:SWS GO:0019363|"GO:pyridine nucleotide biosynthetic process"|Pyridine nucleotide biosynthesis| GO:SWS GO:0006950|"GO:response to stress"|Stress response| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| BL:PDB:NREP 1 BL:PDB:REP 16->272|1qapA|4e-49|41.0|256/289| RP:PDB:NREP 1 RP:PDB:REP 5->274|3c2vA|8e-52|34.5|252/270| RP:PFM:NREP 2 RP:PFM:REP 19->106|PF02749|8e-18|46.6|88/88|QRPTase_N| RP:PFM:REP 108->273|PF01729|4e-51|59.0|166/169|QRPTase_C| HM:PFM:NREP 2 HM:PFM:REP 108->273|PF01729|6.2e-68|52.4|166/169|QRPTase_C| HM:PFM:REP 18->106|PF02749|4.2e-28|44.8|87/88|QRPTase_N| GO:PFM:NREP 4 GO:PFM GO:0004514|"GO:nicotinate-nucleotide diphosphorylase (carboxylating) activity"|PF02749|IPR002638| GO:PFM GO:0009435|"GO:NAD biosynthetic process"|PF02749|IPR002638| GO:PFM GO:0004514|"GO:nicotinate-nucleotide diphosphorylase (carboxylating) activity"|PF01729|IPR002638| GO:PFM GO:0009435|"GO:NAD biosynthetic process"|PF01729|IPR002638| RP:SCP:NREP 2 RP:SCP:REP 4->107|1qapA2|3e-20|32.7|104/122|d.41.2.1| RP:SCP:REP 108->274|1o4uA1|1e-36|39.5|157/162|c.1.17.1| HM:SCP:REP 1->107|1qapA2|9.6e-31|42.1|107/122|d.41.2.1|1/1|Nicotinate/Quinolinate PRTase N-terminal domain-like| HM:SCP:REP 108->276|1o4uA1|6.4e-60|50.9|167/0|c.1.17.1|1/1|Nicotinate/Quinolinate PRTase C-terminal domain-like| OP:NHOMO 986 OP:NHOMOORG 892 OP:PATTERN ---1-1-111111111-11--1211111-1-111111122222111121222211111111-----11 11111-111111-111111-11111111111111111111111111111--111111---111-1111111----111--1111211111111111---1-111111111---------------222222322221111111111112111111111111111111111111111111111111-111111111111111111111111111111111111-1111111-11---------------1----------------------------------------111111111111111111111111----------11-111111111-1111221111--1--11111221111112-11-1-1-1111111-----1121211111112----------1-11111111131-11111111111122111--1-11111111111111111-11111111111111-------------------111112111111111111111122111111111212221113111111112111-11111111111111111-111111-1111111111111112111111111111111-2-------1111111112311122113111111111111111111111-111111--1111------21111111222122211-11112221211221111111111111111111111111111111112222111111111111111--1111111111111111----1---1-----11111111111111111111111111111111111111111111111111111111111111111111111-111111---------------------------------------111-111111 ----11------2111111111111111111111111111111111111-1111-11111111111-1-1--11111111111111---21111111111111111-11121211---1-111111111281---11---1-21--1-1-1--11--11111111--------21111141111111121211111111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 271 STR:RPRED 93.8 SQ:SECSTR ###cHHHHHHHHHHHHHccccccHHHHHccccEEEEEEEEcccEEcccHHHHHHHHHHTTEcccTTcEEcTTccccccEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTccEEEccccccTTTHHHHHHHHHHHTcccccccTTccEEEccccTTccccHHHHHHHHHHHHcTTccEEEEcccHHHHHHHHHHTccEEEcccccHHHHHHHHHHHcTcccEEEEccccTTcccccHTccccEEEcGGGTTTcccccEEEEE############### DISOP:02AL 288-289| PSIPRED ccHHHHHHHHHHHHHHccccccEEEEEEccccEEEEEEEEccccEEEcHHHHHHHHHHccccEEEEEEcccccEEccccEEEEEEEcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccEEEEEcccccHHHHHHHHHHHHHcccccccccccccEEEcHHHHHHHccHHHHHHHHHHHcccccEEEEEEccHHHHHHHHHHcccEEEEccccHHHHHHHHHHccccEEEEEEccccHHHHHHHHHccccEEEEccccccccEEEEEEEEEEEcccHHHccEEcc //