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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : nasF
DDBJ      :nasF         uroporphyrin-III C-methyltransferase
Swiss-Prot:NASF_BACSU   RecName: Full=Uroporphyrinogen-III C-methyltransferase;         Short=Urogen III methylase;         EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;         Short=UROM;

Homologs  Archaea  56/68 : Bacteria  647/915 : Eukaryota  115/199 : Viruses  0/175   --->[See Alignment]
c.113.1c.90.1
:483 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   6->250 1pjtB PDBj 1e-54 44.5 %
:RPS:PDB   8->252 2ek7A PDBj 7e-61 13.7 %
:RPS:SCOP  6->250 1pjqA2  c.90.1.1 * 2e-80 44.6 %
:RPS:SCOP  260->376 1wd7A  c.113.1.1 * 1e-05 23.0 %
:HMM:SCOP  3->260 1s4dA_ c.90.1.1 * 2.5e-76 41.9 %
:HMM:SCOP  255->449 1wd7A_ c.113.1.1 * 1.2e-09 19.1 %
:RPS:PFM   7->219 PF00590 * TP_methylase 4e-21 35.1 %
:HMM:PFM   8->219 PF00590 * TP_methylase 9.5e-50 33.8 204/210  
:HMM:PFM   269->360 PF02602 * HEM4 7.2e-10 28.3 92/229  
:BLT:SWISS 1->483 NASF_BACSU 0.0 100.0 %
:PROS 11->25|PS00839|SUMT_1
:PROS 86->119|PS00840|SUMT_2

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB12122.1 GT:GENE nasF GT:PRODUCT uroporphyrin-III C-methyltransferase GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION complement(353900..355351) GB:FROM 353900 GB:TO 355351 GB:DIRECTION - GB:GENE nasF GB:PRODUCT uroporphyrin-III C-methyltransferase GB:FUNCTION 16.2: Construct biomass (Anabolism) 16.10: Respire GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217486, 15028686, 9765565; Product type e: enzyme GB:PROTEIN_ID CAB12122.1 GB:DB_XREF GOA:P42437 InterPro:IPR006366 SubtiList:BG11098 UniProtKB/Swiss-Prot:P42437 GB:GENE:GENE nasF LENGTH 483 SQ:AASEQ MIMKNGIVYFVGAGPGDPGLLTIKGKQALKEADVILYDRLANPKLLEFASPDCQFIYCGKLPNRHFMKQKEINALLVEKALNGLTVVRLKGGDPSVFGRVGEEADALHEHGIRYEMVPGITSGIAAPLYAGIPVTHRDFASSFAMITAHDKSLKGTPNLDWEGLARSVQTLVFYMGVKNLSYICQQLISYGKSPSVPVIVIQWGTWGRQRSVKGTLENIQQKVQEHQITNPAIIVIGDIVNFQTHSWFESKPLIGRHLMVVTHGEDEDPLADKLRDSGADLIEWPKWRTENMPVNEEILRKIGTFEDVFFTSRRAVCEFFRALASQKIDIRQLTAKLSAASEQAKTELEKRGFLVTAIQPDSEKRLVVGSRHAVENMQKHESCSFYITHENVIDDRFTHMIQRTISESPLHMVICPNKLSVQQLINGGEQIGILPEPSASRPPIVCIGDDSAAGIYGFTAVQEQDELLAFIHNQHAEKKLLHT GT:EXON 1|1-483:0| SW:ID NASF_BACSU SW:DE RecName: Full=Uroporphyrinogen-III C-methyltransferase; Short=Urogen III methylase; EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase; Short=UROM; SW:GN Name=nasF; Synonyms=nasBE; OrderedLocusNames=BSU03280; SW:KW Complete proteome; Methyltransferase; Porphyrin biosynthesis;S-adenosyl-L-methionine; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->483|NASF_BACSU|0.0|100.0|483/483| GO:SWS:NREP 3 GO:SWS GO:0008168|"GO:methyltransferase activity"|Methyltransferase| GO:SWS GO:0006779|"GO:porphyrin biosynthetic process"|Porphyrin biosynthesis| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 11->25|PS00839|SUMT_1|PDOC00656| PROS 86->119|PS00840|SUMT_2|PDOC00656| BL:PDB:NREP 1 BL:PDB:REP 6->250|1pjtB|1e-54|44.5|238/455| RP:PDB:NREP 1 RP:PDB:REP 8->252|2ek7A|7e-61|13.7|241/265| RP:PFM:NREP 1 RP:PFM:REP 7->219|PF00590|4e-21|35.1|205/206|TP_methylase| HM:PFM:NREP 2 HM:PFM:REP 8->219|PF00590|9.5e-50|33.8|204/210|TP_methylase| HM:PFM:REP 269->360|PF02602|7.2e-10|28.3|92/229|HEM4| GO:PFM:NREP 2 GO:PFM GO:0008152|"GO:metabolic process"|PF00590|IPR000878| GO:PFM GO:0008168|"GO:methyltransferase activity"|PF00590|IPR000878| RP:SCP:NREP 2 RP:SCP:REP 6->250|1pjqA2|2e-80|44.6|231/233|c.90.1.1| RP:SCP:REP 260->376|1wd7A|1e-05|23.0|113/254|c.113.1.1| HM:SCP:REP 3->260|1s4dA_|2.5e-76|41.9|258/0|c.90.1.1|1/1|Tetrapyrrole methylase| HM:SCP:REP 255->449|1wd7A_|1.2e-09|19.1|194/0|c.113.1.1|1/1|HemD-like| OP:NHOMO 1597 OP:NHOMOORG 818 OP:PATTERN 11-1-13433333332-2423233222221222322222222222222222222-------222--32 1122323222223233333-33113333333333333333244411112---222111--44433442333--------1122111-211-11111-----2-11312-1---------------3413211113323322---1-334333333332222222333333322221112222122122---13222222212222222221221222233341--2222223211111111111111122221-------------22---------------------------------------------2---------12222222222222222222222321---2222232221-23221-1-32-112222-----232221123333333333333333-42222221131-3444334333342222154333335342222222221112413------------------------------13222111124444443333344443333234442222-211224222233131222121231--21111111232-22121222222221222222232-11-12121-------------------11-11114242222-21211111221111111221421--1331---11122222121111111111-1111111111111111111333333322222222222222222311111111-52112222222211-1---------2122211-1-1---------11111111222244442233333333333---------111131111123233--222221111111112-222222--------1------------------------------22-----111 ------2-------311111111111111111111111111-111111111111-111111111211111111111111111121111-121111111111-1222--1----------------------------------------------------------------1-2222F2222221211111222222 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 250 STR:RPRED 51.8 SQ:SECSTR ##cEccEEEEEEcccccGGGccHHHHHHHHTccEEEEcccccccTTccHHHHHHHHHTccEEEccHHHHHHHHHHHTGGGGGTcEEEEEEcccTTTTccTHHHHHHHHHTTcEEEEEccccHHHHHGGGGTccGGGccccEEEccccTTccccHccEEEEEcEEGGGTEEccHHHHHHHHHHHHHHHccccccTTcEEEEEEcTTccccEEEEEEHHHHTTcccccccccEEEEEcccccHHHHHHHTcccc####################################################################################################################################################################################################################################### DISOP:02AL 1-3| PSIPRED ccccccEEEEEEcccccHHHHHHHHHHHHHHccEEEEEccccHHHHHHcccccEEEEEccccccccccHHHHHHHHHHHHHccccEEEEEcccccccHHHHHHHHHHHHccccEEEEcccHHHHHHHHHHccHHcccccccEEEEEEEcccccccccHHHHHHHHccccEEEEEcccccHHHHHHHHHHHccccccEEEEEEEccccccEEEEEcHHHHHHHHHHccccccEEEEEEccccHHHHHHHcccHHccccEEEEccccccHHHHHHHHHccccEEEEEEEEEcccccHHHHHHHHccccEEEEEcHHHHHHHHHHHHHcccccHHHccEEEEEcHHHHHHHHHcccccEEEccccccEEEEccccccccHHccccccEEEEccccccccHHHHHHHHHHcccEEEEEEccHHHHHHHHHHHHHccccccHHHHccEEEEEccHHHHHHHccccEEccHHHEEEcccccEEHEEEcc //