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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : rpoB
DDBJ      :rpoB         RNA polymerase (beta subunit)
Swiss-Prot:RPOB_BACSU   RecName: Full=DNA-directed RNA polymerase subunit beta;         Short=RNAP subunit beta;         EC=2.7.7.6;AltName: Full=Transcriptase subunit beta;AltName: Full=RNA polymerase subunit beta;

Homologs  Archaea  68/68 : Bacteria  905/915 : Eukaryota  194/199 : Viruses  2/175   --->[See Alignment]
e.29.1
:1193 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   15->281 1ynjC PDBj 5e-54 37.7 %
:BLT:PDB   361->1145 1ynjC PDBj 0.0 60.6 %
:RPS:PDB   8->1144 2e2iB PDBj 0.0 22.8 %
:RPS:SCOP  13->1144 1i6vC  e.29.1.1 * 0.0 52.6 %
:HMM:SCOP  4->1152 1i50B_ e.29.1.1 * 0 49.8 %
:RPS:PFM   29->292 PF04563 * RNA_pol_Rpb2_1 2e-77 57.1 %
:RPS:PFM   369->465 PF04563 * RNA_pol_Rpb2_1 6e-33 60.6 %
:RPS:PFM   469->537 PF04565 * RNA_pol_Rpb2_3 1e-30 80.9 %
:RPS:PFM   555->614 PF10385 * RNA_pol_Rpb2_45 8e-17 63.3 %
:RPS:PFM   620->648,710->1069 PF00562 * RNA_pol_Rpb2_6 e-161 76.9 %
:RPS:PFM   1071->1147 PF04560 * RNA_pol_Rpb2_7 4e-12 51.9 %
:HMM:PFM   623->1069 PF00562 * RNA_pol_Rpb2_6 1.5e-164 63.9 382/386  
:HMM:PFM   28->465 PF04563 * RNA_pol_Rpb2_1 8.1e-40 43.0 165/229  
:HMM:PFM   1071->1144 PF04560 * RNA_pol_Rpb2_7 5e-33 68.9 74/83  
:HMM:PFM   469->538 PF04565 * RNA_pol_Rpb2_3 1.4e-31 57.4 68/68  
:HMM:PFM   547->614 PF10385 * RNA_pol_Rpb2_45 1.6e-27 57.6 66/66  
:BLT:SWISS 1->1193 RPOB_BACSU 0.0 100.0 %
:PROS 922->934|PS01166|RNA_POL_BETA
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB11883.2 GT:GENE rpoB GT:PRODUCT RNA polymerase (beta subunit) GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 121919..125500 GB:FROM 121919 GB:TO 125500 GB:DIRECTION + GB:GENE rpoB GB:PRODUCT RNA polymerase (beta subunit) GB:FUNCTION 16.2: Construct biomass (Anabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10049799, 10744988, 12455702, 12682299, 15060052; Product type e: enzyme GB:PROTEIN_ID CAB11883.2 GB:DB_XREF GOA:P37870 HSSP:1HQM InterPro:IPR007642 SubtiList:BG10728 UniProtKB/Swiss-Prot:P37870 GB:GENE:GENE rpoB LENGTH 1193 SQ:AASEQ MTGQLVQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEGLREMFQDISPIEDFTGNLSLEFIDYSLGEPKYPVEESKERDVTYSAPLRVKVRLINKETGEVKDQDVFMGDFPIMTDTGTFIINGAERVIVSQLVRSPSVYFSGKVDKNGKKGFTATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEILDLIGENEYLRNTLDKDNTENSDKALLEIYERLRPGEPPTVENAKSLLDSRFFDPKRYDLANVGRYKINKKLHIKNRLFNQRLAETLVDPETGEILAEKGQILDRRTLDKVLPYLENGIGFRKLYPNGGVVEDEVTLQSIKIFAPTDQEGEQVINVIGNAYIEEEIKNITPADIISSISYFFNLLHGVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTNTITPQQLINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNRFGFIETPYRRVDPETGKVTGRIDYLTADEEDNYVVAQANARLDDEGAFIDDSIVARFRGENTVVSRNRVDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMQPEAPFVGTGMEYVSGKDSGAAVICKHPGIVERVEAKNVWVRRYEEVDGQKVKGNLDKYSLLKFVRSNQGTCYNQRPIVSVGDEVVKGEILADGPSMELGELALGRNVMVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVGEDALRNLDDRGIIRIGAEVKDGDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIIHDVKVFNREDGDELPPGVNQLVRVYIVQKRKISEGDKMAGRHGNKGVISKILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVLELHMGMAARYLGIHIASPVFDGAREEDVWETLEEAGMSRDAKTVLYDGRTGEPFDNRVSVGIMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGDNVPEPGVPESFKVLIKELQSLGMDVKILSGDEEEIEMRDLEDEEDAKQADGLALSGDEEPEETASADVERDVVTKE GT:EXON 1|1-1193:0| SW:ID RPOB_BACSU SW:DE RecName: Full=DNA-directed RNA polymerase subunit beta; Short=RNAP subunit beta; EC=2.7.7.6;AltName: Full=Transcriptase subunit beta;AltName: Full=RNA polymerase subunit beta; SW:GN Name=rpoB; Synonyms=crsE, rfm; OrderedLocusNames=BSU01070; SW:KW Antibiotic resistance; Complete proteome; DNA-directed RNA polymerase;Nucleotidyltransferase; Transcription; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1193|RPOB_BACSU|0.0|100.0|1193/1193| GO:SWS:NREP 5 GO:SWS GO:0046677|"GO:response to antibiotic"|Antibiotic resistance| GO:SWS GO:0003899|"GO:DNA-directed RNA polymerase activity"|DNA-directed RNA polymerase| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| PROS 922->934|PS01166|RNA_POL_BETA|PDOC00896| SEG 1148->1162|deeeiemrdledeed| BL:PDB:NREP 2 BL:PDB:REP 15->281|1ynjC|5e-54|37.7|266/1114| BL:PDB:REP 361->1145|1ynjC|0.0|60.6|774/1114| RP:PDB:NREP 1 RP:PDB:REP 8->1144|2e2iB|0.0|22.8|1038/1143| RP:PFM:NREP 6 RP:PFM:REP 29->292|PF04563|2e-77|57.1|261/364|RNA_pol_Rpb2_1| RP:PFM:REP 369->465|PF04563|6e-33|60.6|97/364|RNA_pol_Rpb2_1| RP:PFM:REP 469->537|PF04565|1e-30|80.9|68/69|RNA_pol_Rpb2_3| RP:PFM:REP 555->614|PF10385|8e-17|63.3|60/66|RNA_pol_Rpb2_45| RP:PFM:REP 620->648,710->1069|PF00562|e-161|76.9|384/386|RNA_pol_Rpb2_6| RP:PFM:REP 1071->1147|PF04560|4e-12|51.9|77/86|RNA_pol_Rpb2_7| HM:PFM:NREP 5 HM:PFM:REP 623->1069|PF00562|1.5e-164|63.9|382/386|RNA_pol_Rpb2_6| HM:PFM:REP 28->465|PF04563|8.1e-40|43.0|165/229|RNA_pol_Rpb2_1| HM:PFM:REP 1071->1144|PF04560|5e-33|68.9|74/83|RNA_pol_Rpb2_7| HM:PFM:REP 469->538|PF04565|1.4e-31|57.4|68/68|RNA_pol_Rpb2_3| HM:PFM:REP 547->614|PF10385|1.6e-27|57.6|66/66|RNA_pol_Rpb2_45| GO:PFM:NREP 17 GO:PFM GO:0003677|"GO:DNA binding"|PF04563|IPR007644| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF04563|IPR007644| GO:PFM GO:0006350|"GO:transcription"|PF04563|IPR007644| GO:PFM GO:0003677|"GO:DNA binding"|PF04563|IPR007644| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF04563|IPR007644| GO:PFM GO:0006350|"GO:transcription"|PF04563|IPR007644| GO:PFM GO:0003677|"GO:DNA binding"|PF04565|IPR007645| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF04565|IPR007645| GO:PFM GO:0006350|"GO:transcription"|PF04565|IPR007645| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF10385|IPR019462| GO:PFM GO:0006351|"GO:transcription, DNA-dependent"|PF10385|IPR019462| GO:PFM GO:0003677|"GO:DNA binding"|PF00562|IPR007120| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF00562|IPR007120| GO:PFM GO:0006350|"GO:transcription"|PF00562|IPR007120| GO:PFM GO:0003677|"GO:DNA binding"|PF04560|IPR007641| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF04560|IPR007641| GO:PFM GO:0006350|"GO:transcription"|PF04560|IPR007641| RP:SCP:NREP 1 RP:SCP:REP 13->1144|1i6vC|0.0|52.6|1040/1113|e.29.1.1| HM:SCP:REP 4->1152|1i50B_|0|49.8|964/1207|e.29.1.1|1/1|beta and beta-prime subunits of DNA dependent RNA-polymerase| OP:NHOMO 1765 OP:NHOMOORG 1169 OP:PATTERN 11111111111111211111111222222222222222222222224222222211111111111211 1111111111111111111-11111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111111111111111111111111111-112111111111111111111111111111111111111111111111111111111111111111111111111111111111111112111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111121111111111111111111111111111111111111111111111111111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111--1-1111-11111111111111111111-11111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111 33233333833333233333333333333332333333334433333332232333333333333333-33333333-3333333333-35333333333333335337353534243333333342637a3-5443332333423323232353434337G5334233-533944343e33334D56A35C3343334 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-- STR:NPRED 1139 STR:RPRED 95.5 SQ:SECSTR #######ccccccTTHHHHHHHHHHTTcccHHHHHHHHHHHHTHHHHHHcccccccccccEEccEEEEEEEcccEccHHHHHHTTcccEEEEEEEEEcccccccccccccEEEEEEEccTTcTTccGGGccHHHHHHTTccTTccccccTTccccHHHHccEEETTEEEEEcEEEEEccccEEETTEEEcccEEEEEcccEccccccEEEccccccTcEEEEEccccccEEEEEEEEEcccccccccEHEEEEEEEccTTcccccEEEEcTTccccEEHHHHHHHTTcccTTTTGGGTcccTTHHHHHTTcHHHHHHHHHHHHTTTTcccccTTTcccHHHHccccccccccccccccHHHTccTTTccccccHHHHHHHHHHHHHHHHHHHTTccccccTTcGGGEEEEcHHHHHHHHHHHHHHHHTTTcccccccccHHHHHHHHHHHHccTTccccccGGGGTcccccccccHHHHHHHHTEEEcHHHHcccccccccccccccGGGTTTcccccccccTTTTTEEEccTTcEEccccccHHHHHHHTTTEEEcTTccTTTccccEEEEEcccEEEEEccHHHHHHHHHHHHHHTcccTTcEEEEETTTTEEEEEccTTcEEEccEEEccccccccEEcccHHHHHHHHHHHHHHHHTcccEETTGGGTccEEccHHHHcccccccTTccEEcccGGGGcccGGGGccccTTccHHHHHHHHHHGGGccccccTTTTTccccGTTTGGGccccccccEEEcccccTTccccEEEcHHHHHHTTTcEEEEEEEEEccccccTTcccEEcTcccccccccTTccTTccccTTcEEEcccEEEcEEcccccccccTTHHHHTTcccccccccccccEEccTTcEEEEEEEEEEEcTTcccccTTTcEEEEEEEEEEEccccccEEEcccccEEEEEEcccTTTccEETTcccccEEEcGGGcTTTTcHHHHHHHHHHHHHHHHTccEEccccccccHHHHHHHHHHHcccTTcEEcEEcTTTcccccccEEccccccEEccccHHHHcccccccccccccccccccTTTTccccccHHHHHHHHHHTcHHHHHHTTTTccccEEcccccTTccccTccEEEEEEcHHHHHHHHHHHTTTccccccT############################################### DISOP:02AL 1193-1194| PSIPRED ccccEEEEcccEEEEEHHccccccccccHHHHHHHHHHHHHHHHHHHHHHHHccEEcccccEEEEEEEEEEEcccccHHHHHHccccEEEEEEEEEEEEEccccEEEEEEEEEEEEEEEccccEEEEccHHHHHHHHHHHccccEEEccccccccEEEEEEEEEccccEEEEEEccccEEEEEEcccccEEEEEEEHHcccccHHHHHHHHccccHHHHHHHHcccccHHHHHHHHHHHHccccccccHHHHHHHHHHHccHHHHHHHHHccccccEEEEccHHHHHHHHccccccccHHHHHHHHHHHccHHHHHHHHHHHHccccEEEEEccccccHHHHHHHHHHHccccccHHHHHHHHHHccccccccccccHHHHHHHHHHHHHHHHcccccccHHHHcccccccHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccHHHHHHHHHHHccccccEEEEccccHHHHHHHHHcccccccccccccccccccccccHHccEEEEEccccccccccHHHHcEEEEEEcccccccccHHccccccEEEEcEEEcccHHHccccEEEccccEEccccEEEccEEEEEEEccEEEEEEEEEEEEEEEEccEEEEEEEEEcccccccccccccccHHccccccccccHHHcccccEEEEEEcccccEEEEccccEEccccccEEEEEccccccccccccccccEEEcccccccccccEEcccccccccEEEccEEEcccccccccccccccEEEEEEEEcccccccccEEEEHHHHHcccEEEEEEEEEEEEEEEccccccccccccccccHHHHHHHHcccccccccEEccccEEEEEEcccccccccccccEEEEEcccccccEEEEEEEccccccEEEEEEEEEEcccccccccccEEEEEEEEEccccccHHHHHHHccccEEEEEEEEccccccccccccEEEEEEccccccHHccHHHHHHHHHHHHHHHcccEEEEcccccccHHHHHHHHHHccccccccEEEEccccccEEcccEEEEHHHHHHHHHHHcccEEEEEcccccHHHcccccccccccccccccHHHHHHHHHHHHHHHHHHHHcccccEEEccHHHcEEEcccccccccccHHHHHHHHHHHHccccEEEEEccccccccccccccccccccccccccccccHHHccHHHHHccccccc //