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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : rpoC
DDBJ      :rpoC         RNA polymerase (beta' subunit)
Swiss-Prot:RPOC_BACSU   RecName: Full=DNA-directed RNA polymerase subunit beta';         Short=RNAP subunit beta';         EC=2.7.7.6;AltName: Full=Transcriptase subunit beta';AltName: Full=RNA polymerase subunit beta';

Homologs  Archaea  68/68 : Bacteria  906/915 : Eukaryota  196/199 : Viruses  2/175   --->[See Alignment]
e.29.1
:1199 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   10->1176 2ghoD PDBj 0.0 53.4 %
:RPS:PDB   7->186 2ab4A PDBj 6e-26 8.7 %
:RPS:PDB   220->1186 1ddqD PDBj 0.0 51.6 %
:RPS:SCOP  6->1181 2ghoD1  e.29.1.2 * 0.0 53.1 %
:HMM:SCOP  1->1180 1i50A_ e.29.1.2 * 0 48.9 %
:RPS:PFM   10->330 PF04997 * RNA_pol_Rpb1_1 9e-90 62.3 %
:RPS:PFM   333->475 PF00623 * RNA_pol_Rpb1_2 2e-39 60.1 %
:RPS:PFM   478->663 PF04983 * RNA_pol_Rpb1_3 1e-16 38.6 %
:RPS:PFM   692->758 PF05000 * RNA_pol_Rpb1_4 2e-10 49.3 %
:RPS:PFM   770->962,990->1136 PF04998 * RNA_pol_Rpb1_5 3e-64 60.6 %
:HMM:PFM   6->331 PF04997 * RNA_pol_Rpb1_1 1.2e-102 43.5 308/338  
:HMM:PFM   770->1135 PF04998 * RNA_pol_Rpb1_5 2.8e-78 37.6 274/277  
:HMM:PFM   333->474 PF00623 * RNA_pol_Rpb1_2 2.4e-54 52.8 142/166  
:HMM:PFM   478->663 PF04983 * RNA_pol_Rpb1_3 5.4e-39 35.1 151/157  
:HMM:PFM   692->759 PF05000 * RNA_pol_Rpb1_4 5.9e-17 29.4 68/108  
:BLT:SWISS 1->1199 RPOC_BACSU 0.0 100.0 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB11884.2 GT:GENE rpoC GT:PRODUCT RNA polymerase (beta' subunit) GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 125562..129161 GB:FROM 125562 GB:TO 129161 GB:DIRECTION + GB:GENE rpoC GB:PRODUCT RNA polymerase (beta' subunit) GB:FUNCTION 16.2: Construct biomass (Anabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10672039, 10675340, 10910724, 11029421, 9795209, 10438769; Product type e : enzyme GB:PROTEIN_ID CAB11884.2 GB:DB_XREF GOA:P37871 HSSP:1HQM InterPro:IPR012754 SubtiList:BG10729 UniProtKB/Swiss-Prot:P37871 GB:GENE:GENE rpoC LENGTH 1199 SQ:AASEQ MLDVNNFEYMNIGLASPDKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECHCGKYKRVRYKGVVCDRCGVEVTRAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEVIYFASYVVTDPANTPLEKKQLLSEKEYRAYLDKYGNKFQASMGAEAIHKLLQDIDLVKEVDMLKEELKTSQGQRRTRAIKRLEVLEAFRNSGNKPSWMILDVLPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPSIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPHLKMYQCGLPKEMALELFKPFVMKELVEKGLAHNIKSAKRKIERVQPEVWDVLESVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCTAYNADFDGDQMAVHVPLSAEAQAEARILMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERAGAVGEGMVFKNTDEALLAYQNGYVHLHTRVAVAANSLKNVTFTEEQRSKLLITTVGKLVFNEILPESFPYMNEPTKSNIEEKTPDRFFLEKGADVKAVIAQQPINAPFKKGILGKIIAEIFKRFHITETSKMLDRMKNLGFKYSTKAGITVGVSDIVVLDDKQEILEEAQSKVDNVMKQFRRGLITEEERYERVISIWSAAKDVIQGKLMKSLDELNPIYMMSDSGARGNASNFTQLAGMRGLMANPAGRIIELPIKSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIIRETDCGTDRGILAKPLKEGTETIERLEERLIGRFARKQVKHPETGEVLVNENELIDEDKALEIVEAGIEEVWIRSAFTCNTPHGVCKRCYGRNLATGSDVEVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRIQELFEARNPKGQATITEIDGTVVEINEVRDKQQEIVVQGAVETRSYTAPYNSRLKVAEGDKITRGQVLTEGSIDPKELLKVTDLTTVQEYLLHEVQKVYRMQGVEIGDKHVEVMVRQMLRKVRVIDAGDTDVLPGTLLDIHQFTEANKKVLLEGNRPATGRPVLLGITKASLETDSFLSAASFQETTRVLTDAAIKGKRDELLGLKENVIIGKLVPAGTGMMKYRKVKPVSNVQPTDDMVPVE GT:EXON 1|1-1199:0| SW:ID RPOC_BACSU SW:DE RecName: Full=DNA-directed RNA polymerase subunit beta'; Short=RNAP subunit beta'; EC=2.7.7.6;AltName: Full=Transcriptase subunit beta';AltName: Full=RNA polymerase subunit beta'; SW:GN Name=rpoC; Synonyms=lpm, std; OrderedLocusNames=BSU01080; SW:KW Antibiotic resistance; Complete proteome; DNA-directed RNA polymerase;Nucleotidyltransferase; Transcription; Transferase. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->1199|RPOC_BACSU|0.0|100.0|1199/1199| GO:SWS:NREP 5 GO:SWS GO:0046677|"GO:response to antibiotic"|Antibiotic resistance| GO:SWS GO:0003899|"GO:DNA-directed RNA polymerase activity"|DNA-directed RNA polymerase| GO:SWS GO:0016779|"GO:nucleotidyltransferase activity"|Nucleotidyltransferase| GO:SWS GO:0006350|"GO:transcription"|Transcription| GO:SWS GO:0016740|"GO:transferase activity"|Transferase| SEG 259->272|rrvinrnnrlkrll| BL:PDB:NREP 1 BL:PDB:REP 10->1176|2ghoD|0.0|53.4|1140/1196| RP:PDB:NREP 2 RP:PDB:REP 7->186|2ab4A|6e-26|8.7|173/300| RP:PDB:REP 220->1186|1ddqD|0.0|51.6|951/1077| RP:PFM:NREP 5 RP:PFM:REP 10->330|PF04997|9e-90|62.3|302/326|RNA_pol_Rpb1_1| RP:PFM:REP 333->475|PF00623|2e-39|60.1|143/166|RNA_pol_Rpb1_2| RP:PFM:REP 478->663|PF04983|1e-16|38.6|145/145|RNA_pol_Rpb1_3| RP:PFM:REP 692->758|PF05000|2e-10|49.3|67/107|RNA_pol_Rpb1_4| RP:PFM:REP 770->962,990->1136|PF04998|3e-64|60.6|340/471|RNA_pol_Rpb1_5| HM:PFM:NREP 5 HM:PFM:REP 6->331|PF04997|1.2e-102|43.5|308/338|RNA_pol_Rpb1_1| HM:PFM:REP 770->1135|PF04998|2.8e-78|37.6|274/277|RNA_pol_Rpb1_5| HM:PFM:REP 333->474|PF00623|2.4e-54|52.8|142/166|RNA_pol_Rpb1_2| HM:PFM:REP 478->663|PF04983|5.4e-39|35.1|151/157|RNA_pol_Rpb1_3| HM:PFM:REP 692->759|PF05000|5.9e-17|29.4|68/108|RNA_pol_Rpb1_4| GO:PFM:NREP 15 GO:PFM GO:0003677|"GO:DNA binding"|PF04997|IPR007080| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF04997|IPR007080| GO:PFM GO:0006350|"GO:transcription"|PF04997|IPR007080| GO:PFM GO:0003677|"GO:DNA binding"|PF00623|IPR000722| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF00623|IPR000722| GO:PFM GO:0006350|"GO:transcription"|PF00623|IPR000722| GO:PFM GO:0003677|"GO:DNA binding"|PF04983|IPR007066| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF04983|IPR007066| GO:PFM GO:0006350|"GO:transcription"|PF04983|IPR007066| GO:PFM GO:0003677|"GO:DNA binding"|PF05000|IPR007083| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF05000|IPR007083| GO:PFM GO:0006350|"GO:transcription"|PF05000|IPR007083| GO:PFM GO:0003677|"GO:DNA binding"|PF04998|IPR007081| GO:PFM GO:0003899|"GO:DNA-directed RNA polymerase activity"|PF04998|IPR007081| GO:PFM GO:0006350|"GO:transcription"|PF04998|IPR007081| RP:SCP:NREP 1 RP:SCP:REP 6->1181|2ghoD1|0.0|53.1|1150/1196|e.29.1.2| HM:SCP:REP 1->1180|1i50A_|0|48.9|1082/1449|e.29.1.2|1/1|beta and beta-prime subunits of DNA dependent RNA-polymerase| OP:NHOMO 1818 OP:NHOMOORG 1172 OP:PATTERN 22222222222222222222222222221121122212111122224222222222222222221111 1111111111111111111-1111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111112222222222222222222222222222222222222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111211111111111111111111111111112111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-111111111111--1-1111-11111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111111111111111111111111111-11111111111111111111111111111111 35333333934333333342333333333333333333334433333333333233333333333333133243333-4333333333-34333323333333334335473533433323333562324L3-3463323333222323242263133235L633G4323G33634373W33315B63B3582353334 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------1-1-- STR:NPRED 1195 STR:RPRED 99.7 SQ:SECSTR ##cccccccEEcccccHHHHHHHcccccccccccccTTccccccccccccccccccccccccccEEEccTTcEEcccccccTTTTcccccccEEEEEEEEEcccTTHHHHHHHTTTETTEEcccTTccHHHHHTTcccHHHHHHHHGGGccTcccccccccccccccccccccccccEEEEccccEEEEcccEEcHHHHHHHHHcccTHHHHHccccTTccccccccccccccccccGccccccccccccGGGTTTTTcHHHHHHHHTTTcccccccTHHHHHHHHHHHHHHHHHTTccccccccccccccccccTTTTTTTccccccTTcccccccccEEEEEEEccccTTTcccccTTHHHHHHHHHHHHHHHHTcccccHHHHHHHTccccHHHHTTHHHHTTTccEEccccccccGGGTcEEcccccccccEEEcTTTHHHHcccccccEEEEcccccGGGTTTTcccccTTTcccccTTccccccccTTTHHHHHHTccccccccccccccccccHHHHHTTccccccccccccccccccccccccccTTTHHHHHTTcccccccccTTcccccccccccHHHHHHHHHHHHHTTcTTTTTTcccccTTccccHHHHHHHHHHTTcTHHHHHHHHHHHHHHHHHHHHHHccccccTTTcccTTHHHHHHHTTTTTHHHHHHHTTTcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccTTTTTTcccccHHHHHHHcccccccccTTcccccccccTTccccTTcTTHHHHHHHHHHTTTGGGTTTTTcccTHHHHHHTTTTccccccccEccccEcEEEccEEcTTTccEEcccHHHTTccccEEEccccccEEEcccccHHHHHHHHHTcccEEEEccccccccTTTcccccccccTTcccccccccccHHHHGGGGTTGGGccccccccccccccccccccHHHHHHHHTTccccccccccccccHcccccccccccHccccccccccccccccccccccccccccccccccTTcccccccHHHHccHHHHHHHHHHHHHHHHHHTTccccTTcTHHHHHHHHTcEEEEccccccccccccEEHHHHHHHHHTTTcccccccccEEEccccTHHHHHcccccTTTTTcccTTHHHHHHHHccccGGGGccTTHHHHTcccccccccccccccTTGEEEEEcTTccE## DISOP:02AL 1198-1200| PSIPRED ccccccccEEEEEcccHHHHHHHcEEEEEcccccccccccccccccccHHccccccccEEcccccccccccccccccccccccccccccccccEEEEccccccHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHccccccHHHHHHHccHHHHHHHHcccccccccccccHHHHHHHHcccHHHHHHHHHHHHHccccHHHHHcccccHHHHHHcccccccccEEEEEEEccccccccEEEEccccccccHHHHHHHHHHHHHHHHHHHHHcccHHHHHHHHHHHHHHHHHHHHcccccccccccccccccccHHHHHHHHccHHHHHcccccccccccEEEcccccEEEcEEcccHHHHHHHcccHHHHHHHHcccccEEccccHHHHHHccccccHHHHHccccEEEEEcccccccccEEEEEEEEEcccEEEEcHHHcccccccccccEEEEEccccHHHHHHHHHHHcccccEEccccccEEEEEHHHHHHHHHHHHHccccccccccEEccHHHHHHHHHccccccccccccccccccccccccccEEEEEEccccHHHHHHHccccccccccccccccccccccEEEEEcccEEEEEEccHHHccccccHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHccEEEEccccccHHHHHHHHHHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHHHHHHccccccEEEEEcccccccHHHHHHHHHHHHHHHccccccccccccHHHHccccHHHHHHHHHHcHHHHHHHccccccccEEHHHEEHHHccEEEEEcccEEEccEEEEEEEEcccEEEcccccEEEEEEccEEcccccccHHccccccccHHHHHHHHHccccccccHHHHccccHHHHHHHHHcccccccccccHHHHHcHHHHcccccHHHHHHHHHHcccccccccccccccEEEccEEEEEccccEEEEEccccEEEccccccccEEEEEccccEEEEEEcccccEEEEEccccEEEEEEEEcccccHHHHEEEccHHHHHHHHHHHHHHHcccccccccccEEEEEEEccccEEEEEEccccEEEccccccHHHHHHHHHHHHHcccccEEEEEEEEcccccccccccHHHccccccHHHHHHHHHHcccccccccccEEEEEcccccccccHHHHHHHHHHccccccccccccc 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