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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : thiD
DDBJ      :thiD         phosphomethylpyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase
Swiss-Prot:             

Homologs  Archaea  59/68 : Bacteria  747/915 : Eukaryota  110/199 : Viruses  0/175   --->[See Alignment]
c.72.1
:271 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   2->265 2i5bD PDBj 3e-48 43.2 %
:RPS:PDB   25->259 2ajpB PDBj 7e-40 23.9 %
:RPS:SCOP  25->260 1lhpA  c.72.1.5 * 7e-46 25.2 %
:HMM:SCOP  1->266 1jxhA_ c.72.1.2 * 3e-83 41.1 %
:RPS:PFM   25->251 PF08543 * Phos_pyr_kin 3e-55 49.6 %
:HMM:PFM   13->258 PF08543 * Phos_pyr_kin 2e-99 51.4 245/246  
:BLT:SWISS 25->264 THID_HAEIN 1e-56 48.5 %
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB13028.1 GT:GENE thiD GT:PRODUCT phosphomethylpyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 1246837..1247652 GB:FROM 1246837 GB:TO 1247652 GB:DIRECTION + GB:GENE thiD GB:PRODUCT phosphomethylpyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase GB:FUNCTION 16.2: Construct biomass (Anabolism) 16.11: Scavenge (Catabolism) GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 12627963, 14973012, 16952958, 17012797; Product type e: enzyme GB:PROTEIN_ID CAB13028.1 GB:DB_XREF GOA:O31620 HSSP:1JXH InterPro:IPR004399 SubtiList:BG13151 UniProtKB/TrEMBL:O31620 GB:GENE:GENE thiD LENGTH 271 SQ:AASEQ MSIYKALTIAGSDSGGGAGIQADIKTFQELDVFGMSAITAVTAQNTLGVHGVHPLTVETLRQQIDAVAEDLRPDAVKTGMLWNADMIEEVARKIDEYGFNRVIVDPVMIAKGGASLLRDESVATLKELLIPRSYAITPNVPEAETLTGMTISSLDDRKKAAEQLVKMGAQHVIIKGGHQPEDNHITDLLFDGSMFMQITHPYINTKHTHGTGCTFAAALTAQTAKGDSIHQAFEVAANFVREAVENTLGIGSGHGPTNHFAFKRNSLNTSR GT:EXON 1|1-271:0| BL:SWS:NREP 1 BL:SWS:REP 25->264|THID_HAEIN|1e-56|48.5|239/269| SEG 9->24|iagsdsgggagiqadi| BL:PDB:NREP 1 BL:PDB:REP 2->265|2i5bD|3e-48|43.2|264/267| RP:PDB:NREP 1 RP:PDB:REP 25->259|2ajpB|7e-40|23.9|234/301| RP:PFM:NREP 1 RP:PFM:REP 25->251|PF08543|3e-55|49.6|226/245|Phos_pyr_kin| HM:PFM:NREP 1 HM:PFM:REP 13->258|PF08543|2e-99|51.4|245/246|Phos_pyr_kin| RP:SCP:NREP 1 RP:SCP:REP 25->260|1lhpA|7e-46|25.2|234/306|c.72.1.5| HM:SCP:REP 1->266|1jxhA_|3e-83|41.1|265/0|c.72.1.2|1/1|Ribokinase-like| OP:NHOMO 1115 OP:NHOMOORG 916 OP:PATTERN 1111112222222222-1111111111111111111--111---111111111-11111-11111-11 1111111233211111111-1111121111111111121111111131211-222222--111212211112111111111-111111112211-----------11111---------------1111111111111111---111111--11111------1--111111---111-1--11-11111-11322222222222222231222222222222222222222122222221222222122222313-22-2111112222312241222222111111122222222222111111111111112211122211111122222221211111122211-112212-111111-1-11111111111111112222111111111111111111111111-11111111111-111111111111111111-1111121111111111111111111111111111-------------------111111111111111112111111112222121111112-1111111112111111111312111111111111111-111111111122111111111112112111114111111111--111111--1--111111111111121-----11-----112-211--1111------11111111111111111-111111111111111111111111111111111111111111111111111-1111111111111---1111111111111211-1211-111-2211111111111111111111111111111111--------111111111111111111111111111111112111111--------11------------------------------------1-1 -1-----------1111-1111111111111111111111111111-11111111111111111111111111212323311111133-1211111211-111111--11-----------------------------------------------------1-----------1-11-111111132-1111----2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 266 STR:RPRED 98.2 SQ:SECSTR #ccEEEEEEEEEETTcccHHHHHHHHHHHTTccEEEEEEEEEEcccTTcccccEccHHHHHHHHHHHHHTccccEEEEcccccHHHHHHHHHHHHHHHHHcEEEccccEEEcEEEcccGGGHHHHHHTHHHHccEEcccHHHHHHHHTcccccHHHHHHHHHHHHHHcccEEEEcccccccTTcccEEEEEEEEEEEcTTccEEEEEcccHHHHHHHHHHHHHHHcTcHHHHHHHHHHHHHHHHHHHHHHHHHccTTTTcccTTHHH#### DISOP:02AL 268-271| PSIPRED ccccEEEEEEccccccccHHHHHHHHHHHccccccEEccEEEEcccccEEEEEEccHHHHHHHHHHHHHcccccEEEEcccccHHHHHHHHHHHHHcccccEEEccEEEcccccccccHHHHHHHHHHHHcccEEEEccHHHHHHHcccccccHHHHHHHHHHHHHccccEEEEEcccccccccEEEEEEcccEEEEEEcccccccccccHHHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHHHHHcccccccccHHHHccccccccc //