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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : ureC
DDBJ      :ureC         urease (alpha subunit)
Swiss-Prot:URE1_BACSU   RecName: Full=Urease subunit alpha;         EC=3.5.1.5;AltName: Full=Urea amidohydrolase subunit alpha;

Homologs  Archaea  6/68 : Bacteria  321/915 : Eukaryota  90/199 : Viruses  0/175   --->[See Alignment]
b.92.1c.1.9
:569 amino acids
:SECSTR
:PSIPRED
:DISOPRED
:BLT:PDB   1->569 1ubpC PDBj 0.0 60.2 %
:RPS:PDB   2->569 1ejtC PDBj e-121 61.5 %
:RPS:SCOP  2->145 1a5kC1  b.92.1.1 * 7e-34 57.1 %
:RPS:SCOP  133->569 1a5kC2  c.1.9.2 * e-110 59.1 %
:HMM:SCOP  2->182 1e9yB1 b.92.1.1 * 3.4e-66 55.3 %
:HMM:SCOP  132->569 4ubpC2 c.1.9.2 * 1e-193 69.2 %
:RPS:PFM   2->122 PF00449 * Urease_alpha 2e-42 72.0 %
:RPS:PFM   229->305 PF04452 * Methyltrans_RNA 6e-05 28.4 %
:RPS:PFM   410->438 PF01979 * Amidohydro_1 5e-04 58.6 %
:HMM:PFM   128->438 PF01979 * Amidohydro_1 5.9e-67 26.4 288/328  
:HMM:PFM   1->122 PF00449 * Urease_alpha 2.4e-58 73.6 121/121  
:BLT:SWISS 1->569 URE1_BACSU 0.0 100.0 %
:PROS 320->336|PS00145|UREASE_2
:PROS 130->143|PS01120|UREASE_1
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB15681.1 GT:GENE ureC GT:PRODUCT urease (alpha subunit) GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION complement(3766714..3768423) GB:FROM 3766714 GB:TO 3768423 GB:DIRECTION - GB:GENE ureC GB:PRODUCT urease (alpha subunit) GB:FUNCTION 16.11: Scavenge (Catabolism) 16.8: Protect GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12401490, 16199586, 9287005; Product type e: enzyme GB:PROTEIN_ID CAB15681.1 GB:DB_XREF GOA:P77837 HSSP:1FWB InterPro:IPR017950 SubtiList:BG11983 UniProtKB/Swiss-Prot:P77837 GB:GENE:GENE ureC LENGTH 569 SQ:AASEQ MKMSREEYAELFGPTTGDKIRLGDTDLWIEVEKDFTVYGEEMIFGGGKTIRDGMGQNGRITGKDGALDLVITNVVLLDYTGIVKADVGVKDGRIVGVGKSGNPDIMDGVDPHMVIGAGTEVISGEGKILTAGGVDTHIHFICPQQMEVALSSGVTTLLGGGTGPATGSKATTCTSGAWYMARMLEAAEEFPINVGFLGKGNASDKAPLIEQVEAGAIGLKLHEDWGTTPSAIKTCMEVVDEADIQVAIHTDTINEAGFLENTLDAIGDRVIHTYHIEGAGGGHAPDIMKLASYANILPSSTTPTIPYTVNTMDEHLDMMMVCHHLDAKVPEDVAFSHSRIRAATIAAEDILHDIGAISMTSSDSQAMGRVGEVIIRTWQVADKMKKQRGALAGENGNDNVRAKRYIAKYTINPAITHGLSHEVGSVEKGKLADLVLWDPVFFGVKPELVLKGGMIARAQMGDPNASIPTPEPVFMRQMYASYGKANRSTSITFMSQASIERGVAESLGLEKRISPVKNIRKLSKLDMKLNSALPKIEIDPKTYQVFADGEELSCQPVDYVPLGQRYFLF GT:EXON 1|1-569:0| SW:ID URE1_BACSU SW:DE RecName: Full=Urease subunit alpha; EC=3.5.1.5;AltName: Full=Urea amidohydrolase subunit alpha; SW:GN Name=ureC; OrderedLocusNames=BSU36640; SW:KW Complete proteome; Cytoplasm; Hydrolase; Metal-binding; Nickel. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->569|URE1_BACSU|0.0|100.0|569/569| GO:SWS:NREP 3 GO:SWS GO:0005737|"GO:cytoplasm"|Cytoplasm| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0046872|"GO:metal ion binding"|Metal-binding| PROS 320->336|PS00145|UREASE_2|PDOC00133| PROS 130->143|PS01120|UREASE_1|PDOC00133| SEG 149->172|alssgvttllgggtgpatgskatt| BL:PDB:NREP 1 BL:PDB:REP 1->569|1ubpC|0.0|60.2|568/569| RP:PDB:NREP 1 RP:PDB:REP 2->569|1ejtC|e-121|61.5|563/565| RP:PFM:NREP 3 RP:PFM:REP 2->122|PF00449|2e-42|72.0|118/119|Urease_alpha| RP:PFM:REP 229->305|PF04452|6e-05|28.4|74/225|Methyltrans_RNA| RP:PFM:REP 410->438|PF01979|5e-04|58.6|29/271|Amidohydro_1| HM:PFM:NREP 2 HM:PFM:REP 128->438|PF01979|5.9e-67|26.4|288/328|Amidohydro_1| HM:PFM:REP 1->122|PF00449|2.4e-58|73.6|121/121|Urease_alpha| GO:PFM:NREP 6 GO:PFM GO:0009039|"GO:urease activity"|PF00449|IPR011612| GO:PFM GO:0016151|"GO:nickel ion binding"|PF00449|IPR011612| GO:PFM GO:0019627|"GO:urea metabolic process"|PF00449|IPR011612| GO:PFM GO:0006364|"GO:rRNA processing"|PF04452|IPR006700| GO:PFM GO:0008168|"GO:methyltransferase activity"|PF04452|IPR006700| GO:PFM GO:0016787|"GO:hydrolase activity"|PF01979|IPR006680| RP:SCP:NREP 2 RP:SCP:REP 2->145|1a5kC1|7e-34|57.1|140/181|b.92.1.1| RP:SCP:REP 133->569|1a5kC2|e-110|59.1|384/385|c.1.9.2| HM:SCP:REP 2->182|1e9yB1|3.4e-66|55.3|179/0|b.92.1.1|1/2|Composite domain of metallo-dependent hydrolases| HM:SCP:REP 132->569|4ubpC2|1e-193|69.2|390/391|c.1.9.2|1/1|Metallo-dependent hydrolases| OP:NHOMO 483 OP:NHOMOORG 417 OP:PATTERN ------1--------1--------1---1--1----------------------------------1- ----1--1111-111--11-12--1211111111111211-1111-1-----11111-------1-3223-----1----------------1--------1---11-------------------------------------111-11--111--1111-1111-111111-11111-1-1--1-------1------1---------1---1----1-1----------1-11111111111111111-1---------------------------------------------------------------111---------------------------1-11-------------------1---------------11133---1111122222222222-3413313211--111111111111111--111111111111111111----1---------------------------------------111-1111111111111211111111111111-1111111--111111-11-1-1-1---------1-11--------------------------11-1--1----------211111111---------1111---11-------1--------------11-1------1---11--12--------1---------1--------111--111--------------------------11111111111111------------1111111----1111----1121111-2-1-11111111111111112-----------11---------------------------1----------------------------------------111-----------1- -------------2111111121111111111111111111111111111211211111111------------------------11-12111211111121221--2-3----------------------------------------------------21--------2-----8111--1-111111111113 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- STR:NPRED 569 STR:RPRED 100.0 SQ:SECSTR HcccHHHHHHHHcccTTcEEEcTTcccEEEccEEcccTTccccccTTcccccTTTcccccccGGGcccEEEEEEEEEETTEEEEEEEEEETTEEEEEEcEEcTTTcccccGcEEccTTcEEEEcTTcEEEEcEEEEEEEcccTHHHHHHHHHTEEEEEEEcccccHHHHHcccccHHHHHHHHHHHHTTcccEEEEEEEcccccHHHHHHHHHHTccEEEEcGGGcccHHHHHHHHHHHHHHTcEEEEcccTTcccccHHHHHHHHTTccEEETTTTcTTcccTTTGGGGGGcTTEEEEEEcTTccccTTHHHHHHHHHHHHHTccTTcHHHHHHHHTTccHHHHHHHHHHHHTTcccEEEccTTccccTTcHHHHHHHHHHHHHHHHcccTTcccccHHHHHHHHHTTTHHHHHHTTcTTTcccccTTccccEEEEcGGGTTTcccEEEETTEEEEEEEccTTcccccccccEEEEcGGGcHHHHHHHcEEEEcHHHHHTTHHHHHTcccEEEEcccTTTccGGGcTTccccccEEEcTTTccEEETTEEccccccccccccTTTccc DISOP:02AL 1-3, 52-65| PSIPRED ccccHHHHHHHHccccccEEEEEcccEEEEEEccccccccEEEEccccEEcccccccccccccccccEEEEEccEEEcccccEEEEEEEEccEEEEEccccccccccccccccccccccEEEEccccEEEcccEEEEEEEEccccHHHHHHcccEEEEEcccccccccccccccccHHHHHHHHHHHHcccccEEEEEccccccHHHHHHHHHccEEEEEEEccccccHHHHHHHHHHHHHcccEEEEEEcccccccHHHHHHHHHccccEEEEEccccccccHHHHHHHHccccccccccccccccHHHHHHHHHHHHHHHHccccccHHHHHHHHHcccHHHHHHHHHHHHHHHHEEEccccHHccccccEEEEHHHHHHHHHHHHccccccccccHHHHHHHHHHHcccHHHHHcHHHHccccccccEEEEEEEccccccccccEEEEccEEEEEEccccccccccccccccccHHHHccccccccEEEEEEHHHHHcccHHHcccccEEEEEcccccccHHHHHcccccccEEEcccEEEEEEccEEEEcccccccccccccccc //