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Bacillus subtilis subsp. subtilis str. 168 (bsub0)
Gene : yheH
DDBJ      :yheH         ABC transporter (ATP-binding protein) involved in the signalling pathway that activates KinA during sporulation initiation
Swiss-Prot:YHEH_BACSU   RecName: Full=Probable multidrug resistance ABC transporter ATP-binding/permease protein yheH;         EC=3.6.3.-;

Homologs  Archaea  68/68 : Bacteria  908/915 : Eukaryota  197/199 : Viruses  1/175   --->[See Alignment]
c.37.1f.37.1
:673 amino acids
:PSIPRED
:DISOPRED
:BLT:PDB   151->665 2hydA PDBj 4e-86 34.6 %
:RPS:PDB   168->667 3b60A PDBj 7e-71 27.6 %
:RPS:SCOP  149->413 2hydA2  f.37.1.1 * 1e-49 22.9 %
:RPS:SCOP  430->640 1sgwA  c.37.1.12 * 1e-41 24.0 %
:HMM:SCOP  1->421 1pf4A2 f.37.1.1 * 1.2e-69 27.7 %
:HMM:SCOP  430->650 1pf4A1 c.37.1.12 * 6.5e-64 39.8 %
:RPS:PFM   145->382 PF00664 * ABC_membrane 6e-25 28.2 %
:RPS:PFM   425->487 PF03193 * DUF258 6e-04 37.9 %
:RPS:PFM   470->595 PF00005 * ABC_tran 3e-12 43.2 %
:HMM:PFM   152->385 PF00664 * ABC_membrane 1.3e-34 24.2 231/275  
:HMM:PFM   470->595 PF00005 * ABC_tran 5.5e-21 36.8 114/118  
:HMM:PFM   440->487 PF03193 * DUF258 2.1e-06 34.0 47/161  
:BLT:SWISS 1->673 YHEH_BACSU 0.0 100.0 %
:PROS 567->581|PS00211|ABC_TRANSPORTER_1
:TM
:SEG

SeqInfo AminoSeq See neighboring genes
Links GIB DAD Abbreviations Back to title page
GT:ID CAB12811.1 GT:GENE yheH GT:PRODUCT ABC transporter (ATP-binding protein) involved in the signalling pathway that activates KinA during sporulation initiation GT:DATABASE GIB00011CH01 GT:ORG bsub0 GB:ACCESSION GIB00011CH01 GB:LOCATION 1047072..1049093 GB:FROM 1047072 GB:TO 1049093 GB:DIRECTION + GB:GENE yheH GB:PRODUCT ABC transporter (ATP-binding protein) involved in the signalling pathway that activates KinA during sporulation initiation GB:FUNCTION 16.1: Circulate 16.3: Control GB:NOTE Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15855514, 16487324; Product type t: transporter GB:PROTEIN_ID CAB12811.1 GB:DB_XREF GOA:O07549 HSSP:1MV5 InterPro:IPR003593 SubtiList:BG13040 UniProtKB/Swiss-Prot:O07549 GB:GENE:GENE yheH LENGTH 673 SQ:AASEQ MKIGKTLWRYALLYRKLLITAVLLLTVAVGAELTGPFIGKKMIDDHILGIEKTWYEAAEKDKNAVQFHGVSYVREDRLQEPVSKAKEAHIYQVGMAFYFVDQAVSFDGNRTVSDGKLTITNGDKSRAYAAEKLTKQELFQFYQPEIKGMVLLICLYGGLLVFSVFFQYGQHYLLQMSANRIIQKMRQDVFSHIQKMPIRYFDNLPAGKVVARITNDTEAIRDLYVTVLSTFVTSGIYMFGIFTALFLLDVKLAFVCLAIVPIIWLWSVIYRRYASYYNQKIRSINSDINAKMNESIQGMTIIQAFRHQKETMREFEELNESHFYFQNRMLNLNSLMSHNLVNVIRNLAFVCLIWHFGGASLNAAGIVSIGVLYAFVDYLNRLFQPITGIVNQFSKLELARVSAGRVFELLEEKNTEEAGEPAKERALGRVEFRDVSFAYQEGEEVLKHISFTAQKGETVALVGHTGSGKSSILNLLFRFYDAQKGDVLIDGKSIYNMSRQELRSHMGIVLQDPYLFSGTIGSNVSLDDERMTEEEIKNALRQVGAEPLLKKLPKGINEPVIEKGSTLSSGERQLISFARALAFDPAILILDEATAHIDTETEAVIQKALDVVKQGRTTFVIAHRLSTIRNADQILVLDKGEIVERGNHEELMALEGQYYQMYELQKGQKHSIA GT:EXON 1|1-673:0| SW:ID YHEH_BACSU SW:DE RecName: Full=Probable multidrug resistance ABC transporter ATP-binding/permease protein yheH; EC=3.6.3.-; SW:GN Name=yheH; OrderedLocusNames=BSU09720; SW:KW Antibiotic resistance; ATP-binding; Cell membrane; Complete proteome;Hydrolase; Membrane; Nucleotide-binding; Transmembrane; Transport. SW:EXACT T SW:FUNC + BL:SWS:NREP 1 BL:SWS:REP 1->673|YHEH_BACSU|0.0|100.0|673/673| GO:SWS:NREP 8 GO:SWS GO:0046677|"GO:response to antibiotic"|Antibiotic resistance| GO:SWS GO:0005524|"GO:ATP binding"|ATP-binding| GO:SWS GO:0005886|"GO:plasma membrane"|Cell membrane| GO:SWS GO:0016787|"GO:hydrolase activity"|Hydrolase| GO:SWS GO:0016020|"GO:membrane"|Membrane| GO:SWS GO:0000166|"GO:nucleotide binding"|Nucleotide-binding| GO:SWS GO:0016021|"GO:integral to membrane"|Transmembrane| GO:SWS GO:0006810|"GO:transport"|Transport| PROS 567->581|PS00211|ABC_TRANSPORTER_1|PDOC00185| TM:NTM 4 TM:REGION 8->30| TM:REGION 144->166| TM:REGION 220->242| TM:REGION 248->270| SEG 17->34|llitavllltvavgaelt| SEG 329->343|mlnlnslmshnlvnv| BL:PDB:NREP 1 BL:PDB:REP 151->665|2hydA|4e-86|34.6|512/578| RP:PDB:NREP 1 RP:PDB:REP 168->667|3b60A|7e-71|27.6|497/572| RP:PFM:NREP 3 RP:PFM:REP 145->382|PF00664|6e-25|28.2|234/274|ABC_membrane| RP:PFM:REP 425->487|PF03193|6e-04|37.9|58/160|DUF258| RP:PFM:REP 470->595|PF00005|3e-12|43.2|111/123|ABC_tran| HM:PFM:NREP 3 HM:PFM:REP 152->385|PF00664|1.3e-34|24.2|231/275|ABC_membrane| HM:PFM:REP 470->595|PF00005|5.5e-21|36.8|114/118|ABC_tran| HM:PFM:REP 440->487|PF03193|2.1e-06|34.0|47/161|DUF258| GO:PFM:NREP 9 GO:PFM GO:0005524|"GO:ATP binding"|PF00664|IPR001140| GO:PFM GO:0006810|"GO:transport"|PF00664|IPR001140| GO:PFM GO:0016021|"GO:integral to membrane"|PF00664|IPR001140| GO:PFM GO:0042626|"GO:ATPase activity, coupled to transmembrane movement of substances"|PF00664|IPR001140| GO:PFM GO:0055085|"GO:transmembrane transport"|PF00664|IPR001140| GO:PFM GO:0003924|"GO:GTPase activity"|PF03193|IPR004881| GO:PFM GO:0005525|"GO:GTP binding"|PF03193|IPR004881| GO:PFM GO:0005524|"GO:ATP binding"|PF00005|IPR003439| GO:PFM GO:0016887|"GO:ATPase activity"|PF00005|IPR003439| RP:SCP:NREP 2 RP:SCP:REP 149->413|2hydA2|1e-49|22.9|262/323|f.37.1.1| RP:SCP:REP 430->640|1sgwA|1e-41|24.0|196/200|c.37.1.12| HM:SCP:REP 1->421|1pf4A2|1.2e-69|27.7|311/311|f.37.1.1|1/1|ABC transporter transmembrane region| HM:SCP:REP 430->650|1pf4A1|6.5e-64|39.8|221/244|c.37.1.12|1/1|P-loop containing nucleoside triphosphate hydrolases| OP:NHOMO 43696 OP:NHOMOORG 1174 OP:PATTERN JIG8MFGHNMLIOKPGaCDCCFDRjGJQaGVLE7BCC7CCEB8ORKMgFP*pX6NVMMNHLHD7Q175 LOfF*VVXiiiRPQQNOII-IV88R*IIIIIIdYWZg***EnP*jlmaiWSKvsqILcBCZdhY*Zl***WWYXXpaXcJ*bcCAAADUUMJ4JEHJ--DEQJJGVKWGR67767766865555ESLHRZLJSSXOUednlDCDxNoiiobbdUSOPOHKJNHVaWc***TKQHKJJHOKLJKQPQFEoi9Uhz************************bku**jnvvwttu**ajkkkkhfiijjjihVZVWYxlYbz*aNicqtqPP**cVPZikilnppuzwrz*rrsuspqntuoqrZaZYZaccebbZawqpmkkqpsjl*u*********f*en***Vddb*mgqyvhnNG**oeMTffSSlboiOYaPLTMLLIJLHIMdN***UNf*wp*m**z****uy**-bf*cY*az**NB**************HHGrx**v***x*ONOOOOOOgRUHMcLv77656777766868AC79896977985A6GB9F9Ev**h*w*****pijkfxx**vossaw*y*rt*k8KomdvabaXzo*t**PcYIQGLZLDFCBDBBNMNRYVYi*NaOdaQZmRRYGVUXOMRbOYGJMFhlXqKIGOEFGGHIE799999999GMEFJHHnjnNeNUFSJoOSUVRLQXSSTRPUaYUXV5-FGOKI322333*m**S*squuxrvuxop-spqqrotosstxtnopnno*****mnghmfhgiiihhhghghg*mihmmkmT5************24IECFCCDLLMMGExc*ZXWZXVIRSQPSQUdKNQNNFQEGReZhijjo*v*juvnkY***DBCBBECBBHbnlzjkjjju*uuwJNLEIFFIHJDDDD77KRQPGGHI67664656*8WCA86D-ACB8DFAOOKAAJA8AAAAVhpVUg*kliCWJ 5688ebL-fJ8AWcWMQRJNTWSjXjQNNDHHHVWRGQPNOLKFFGWPSeZcjgNMXMOIJKHDD89A3EA5DEFBD2FE8DDAFE8A-XlFQSTRHHIMEBLVSJ6M*o*jkb*r*SMQMPcMxxN*I**u2*Z*PNTImQU*jHUMPHjLI*PdVauTt*U*YbP*Yh*ws*bHJJF*AG9JLxlj*Ls*LN*oz*Z ------------------------------------------------------------------------------------------------------------------------------1------------------------------------------------ DISOP:02AL 1-2, 58-72, 74-84, 412-426, 665-673| PSIPRED ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccEEEccccEEEEcccccccccccccccccccEEEEEEccccccccccEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccHHHHcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccccccccccccccEEEEEEEEEEEcccccHHHccccEEEccccEEEEEccccccHHHHHHHHHHcccccccEEEEccEEcccccHHHHHHHccccccccEEEcccHHHHHHHccccccHHHHHHHHHHHHHHHHHHHccHHccccccccccccccHHHHHHHHHHHHHHcccEEEEEHHHHHccHHHHHHHHHHHHHHHHcccEEEEEccHHHHHHccEEEEEEccEEEEEccHHHHHHcccHHHHHHHHHHHHHHccc //